locus-tag	class	description
NYE86_00010	COG0592	DNA-directed DNA polymerase activity
NYE86_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NYE86_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NYE86_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NYE86_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NYE86_00065	COG0515	serine threonine protein kinase
NYE86_00085	COG0667	Aldo Keto reductase
NYE86_00120	COG0640	Transcriptional regulator
NYE86_00130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NYE86_00145	COG0477	Major facilitator Superfamily
NYE86_00160	COG0705	Rhomboid family
NYE86_00190	COG3764	Sortase (surface protein transpeptidase)
NYE86_00195	COG0515	serine threonine protein kinase
NYE86_00220	COG1716	ATPase activity
NYE86_00225	COG1716	ATPase activity
NYE86_00235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NYE86_00265	COG2172	sigma factor antagonist activity
NYE86_00265	COG2208	phosphoserine phosphatase activity
NYE86_00265	COG1366	Belongs to the anti-sigma-factor antagonist family
NYE86_00310	COG1250	3-hydroxyacyl-CoA dehydrogenase
NYE86_00315	COG1309	transcriptional regulator
NYE86_00325	COG1522	sequence-specific DNA binding
NYE86_00365	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NYE86_00400	COG3033	Beta-eliminating lyase
NYE86_00405	COG0604	alcohol dehydrogenase
NYE86_00405	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_00405	COG3321	synthase
NYE86_00415	COG1136	(ABC) transporter
NYE86_00415	COG4591	ABC-type transport system involved in lipoprotein release permease component
NYE86_00430	COG0515	serine threonine protein kinase
NYE86_00435	COG0515	serine threonine protein kinase
NYE86_00455	COG0022	dehydrogenase e1 component
NYE86_00515	COG1362	aminopeptidase activity
NYE86_00520	COG1960	acyl-CoA dehydrogenase activity
NYE86_00530	COG1741	Belongs to the pirin family
NYE86_00555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NYE86_00605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NYE86_00610	COG1595	DNA-templated transcription, initiation
NYE86_00620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NYE86_00660	COG4591	ABC-type transport system involved in lipoprotein release permease component
NYE86_00660	COG1136	(ABC) transporter
NYE86_00665	COG0577	efflux transmembrane transporter activity
NYE86_00665	COG1136	(ABC) transporter
NYE86_00675	COG0745	RESPONSE REGULATOR receiver
NYE86_00680	COG2205	protein histidine kinase activity
NYE86_00700	COG0667	Aldo Keto reductase
NYE86_00705	COG1280	lysine exporter protein (LysE YggA)
NYE86_00755	COG0667	Aldo Keto reductase
NYE86_00760	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NYE86_00765	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NYE86_00770	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NYE86_00785	COG0667	Aldo Keto reductase
NYE86_00795	COG2197	response regulator
NYE86_00805	COG1136	(ABC) transporter
NYE86_00805	COG0577	efflux transmembrane transporter activity
NYE86_00830	COG0667	Aldo Keto reductase
NYE86_00835	COG0726	polysaccharide deacetylase
NYE86_00855	COG2205	protein histidine kinase activity
NYE86_00860	COG0745	RESPONSE REGULATOR receiver
NYE86_00870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NYE86_00890	COG3509	depolymerase
NYE86_00900	COG1609	Transcriptional regulator
NYE86_00915	COG1396	sequence-specific DNA binding
NYE86_00920	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
NYE86_00935	COG0640	Transcriptional regulator
NYE86_00975	COG4632	Exopolysaccharide biosynthesis protein
NYE86_00975	COG5434	Belongs to the glycosyl hydrolase 28 family
NYE86_01005	COG4566	intracellular signal transduction
NYE86_01010	COG1136	(ABC) transporter
NYE86_01010	COG0577	efflux transmembrane transporter activity
NYE86_01060	COG2837	iron assimilation
NYE86_01070	COG0640	Transcriptional regulator
NYE86_01085	COG1309	transcriptional regulator
NYE86_01090	COG3979	chitinase
NYE86_01105	COG1408	metallophosphoesterase
NYE86_01175	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NYE86_01180	COG2318	DinB family
NYE86_01230	COG1595	DNA-templated transcription, initiation
NYE86_01240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NYE86_01250	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NYE86_01265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NYE86_01320	COG0402	S-adenosylhomocysteine deaminase activity
NYE86_01325	COG1414	Transcriptional regulator
NYE86_01330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NYE86_01380	COG0477	Major facilitator Superfamily
NYE86_01400	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_01405	COG0657	acetylesterase activity
NYE86_01415	COG1278	Cold shock
NYE86_01430	COG1376	ErfK ybiS ycfS ynhG family protein
NYE86_01465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NYE86_01470	COG0326	Molecular chaperone. Has ATPase activity
NYE86_01505	COG3226	Transcriptional regulator
NYE86_01545	COG2318	DinB family
NYE86_01585	COG0604	alcohol dehydrogenase
NYE86_01605	COG0539	negative regulation of cytoplasmic translation
NYE86_01680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NYE86_01695	COG1408	metallophosphoesterase
NYE86_01700	COG1610	YqeY-like protein
NYE86_01705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NYE86_01715	COG0003	Pfam Anion-transporting ATPase
NYE86_01740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NYE86_01745	COG2124	cytochrome p450
NYE86_01750	COG3559	Exporter of polyketide antibiotics
NYE86_01755	COG1131	(ABC) transporter
NYE86_01770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NYE86_01785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NYE86_01790	COG1802	Transcriptional regulator
NYE86_01805	COG0151	Belongs to the GarS family
NYE86_01820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NYE86_01840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NYE86_01845	COG0047	phosphoribosylformylglycinamidine synthase activity
NYE86_01850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NYE86_01865	COG3629	intracellular signal transduction
NYE86_01865	COG3903	Transcriptional regulator
NYE86_01885	COG2318	DinB family
NYE86_01990	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NYE86_02000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NYE86_02020	COG1643	Atp-dependent helicase
NYE86_02045	COG0662	Cupin 2, conserved barrel domain protein
NYE86_02055	COG2319	Wd-40 repeat
NYE86_02055	COG4249	Peptidase C14 caspase catalytic subunit p20
NYE86_02075	COG1609	Transcriptional regulator
NYE86_02080	COG0395	ABC-type sugar transport system, permease component
NYE86_02085	COG4209	transmembrane transport
NYE86_02125	COG2197	response regulator
NYE86_02130	COG0823	Involved in the tonB-independent uptake of proteins
NYE86_02140	COG1222	aaa ATPase
NYE86_02250	COG0640	Transcriptional regulator
NYE86_02255	COG3629	intracellular signal transduction
NYE86_02255	COG3903	Transcriptional regulator
NYE86_02305	COG0513	Belongs to the DEAD box helicase family
NYE86_02385	COG1051	belongs to the nudix hydrolase family
NYE86_02390	COG0494	nUDIX hydrolase
NYE86_02460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NYE86_02480	COG2197	response regulator
NYE86_02525	COG1846	Transcriptional regulator
NYE86_02530	COG0477	Major facilitator Superfamily
NYE86_02570	COG0741	lytic transglycosylase activity
NYE86_02570	COG1196	nuclear chromosome segregation
NYE86_02570	COG0739	heme binding
NYE86_02590	COG0556	nucleotide-excision repair
NYE86_02605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NYE86_02610	COG0579	oxidoreductase
NYE86_02625	COG0697	spore germination
NYE86_02635	COG0470	DNA polymerase III
NYE86_02645	COG0596	Alpha beta hydrolase
NYE86_02660	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_02685	COG4221	oxidoreductase activity
NYE86_02700	COG1252	NADH dehydrogenase
NYE86_02705	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_02730	COG0477	Major facilitator Superfamily
NYE86_02745	COG0326	Molecular chaperone. Has ATPase activity
NYE86_02755	COG0657	acetylesterase activity
NYE86_02805	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_02810	COG3903	Transcriptional regulator
NYE86_02810	COG3629	intracellular signal transduction
NYE86_02815	COG1088	dTDP-glucose 4,6-dehydratase activity
NYE86_02830	COG1819	glycosyl
NYE86_02865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYE86_02880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NYE86_02885	COG0022	dehydrogenase e1 component
NYE86_02890	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_02895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYE86_02930	COG3458	cephalosporin-C deacetylase activity
NYE86_02935	COG1609	Transcriptional regulator
NYE86_02940	COG4209	transmembrane transport
NYE86_02945	COG0395	ABC-type sugar transport system, permease component
NYE86_02950	COG1653	transport
NYE86_02980	COG0714	Associated with various cellular activities
NYE86_03005	COG0640	Transcriptional regulator
NYE86_03065	COG1309	transcriptional regulator
NYE86_03070	COG0300	oxidoreductase activity
NYE86_03075	COG0189	ligase activity
NYE86_03085	COG0657	acetylesterase activity
NYE86_03110	COG0412	Dienelactone hydrolase
NYE86_03120	COG2814	Major facilitator Superfamily
NYE86_03135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NYE86_03150	COG2353	YceI-like domain
NYE86_03185	COG0671	phosphoesterase, PA-phosphatase related
NYE86_03190	COG0586	Pfam SNARE associated Golgi protein
NYE86_03200	COG0501	Belongs to the peptidase M48B family
NYE86_03225	COG3795	YCII-related domain
NYE86_03230	COG4941	Belongs to the sigma-70 factor family
NYE86_03240	COG3903	Transcriptional regulator
NYE86_03240	COG3629	intracellular signal transduction
NYE86_03300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NYE86_03330	COG0515	serine threonine protein kinase
NYE86_03330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NYE86_03350	COG2161	toxin-antitoxin pair type II binding
NYE86_03355	COG4115	mRNA cleavage
NYE86_03360	COG1077	Cell shape determining protein MreB Mrl
NYE86_03370	COG3360	Dodecin
NYE86_03385	COG0076	glutamate decarboxylase activity
NYE86_03390	COG3842	ATPase activity
NYE86_03395	COG0586	Pfam SNARE associated Golgi protein
NYE86_03405	COG2027	D-alanyl-D-alanine carboxypeptidase
NYE86_03410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NYE86_03420	COG0037	tRNA processing
NYE86_03435	COG0302	gtp cyclohydrolase
NYE86_03445	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NYE86_03445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NYE86_03450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NYE86_03460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NYE86_03465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NYE86_03490	COG1174	glycine betaine transport
NYE86_03510	COG1595	DNA-templated transcription, initiation
NYE86_03515	COG0649	NAD binding
NYE86_03530	COG1105	Belongs to the carbohydrate kinase PfkB family
NYE86_03575	COG0463	Glycosyl transferase, family 2
NYE86_03590	COG1278	Cold shock
NYE86_03605	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NYE86_03610	COG1737	Transcriptional regulator
NYE86_03625	COG0326	Molecular chaperone. Has ATPase activity
NYE86_03650	COG0148	phosphopyruvate hydratase activity
NYE86_03680	COG1131	(ABC) transporter
NYE86_03690	COG3973	AAA domain
NYE86_03715	COG1061	Type III restriction enzyme res subunit
NYE86_03745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NYE86_03750	COG1120	ATPase activity
NYE86_03755	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYE86_03760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYE86_03780	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NYE86_03785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NYE86_03795	COG2814	Major facilitator Superfamily
NYE86_03810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NYE86_03820	COG2252	PERMEase
NYE86_03845	COG0667	Aldo Keto reductase
NYE86_03870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NYE86_03875	COG0247	lactate metabolic process
NYE86_03875	COG0277	FAD linked oxidase domain protein
NYE86_03885	COG0259	pyridoxamine-phosphate oxidase activity
NYE86_03895	COG4821	SIS domain
NYE86_03905	COG0596	Alpha beta hydrolase
NYE86_03905	COG2945	thiolester hydrolase activity
NYE86_03980	COG2814	Major facilitator Superfamily
NYE86_04045	COG4977	sequence-specific DNA binding
NYE86_04055	COG2072	flavoprotein involved in K transport
NYE86_04065	COG1309	transcriptional regulator
NYE86_04075	COG0515	serine threonine protein kinase
NYE86_04075	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NYE86_04115	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NYE86_04135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYE86_04155	COG1686	Belongs to the peptidase S11 family
NYE86_04185	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NYE86_04200	COG0564	pseudouridine synthase activity
NYE86_04215	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NYE86_04250	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_04270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_04290	COG1119	ATPase activity
NYE86_04315	COG3384	dioxygenase
NYE86_04320	COG1247	-acetyltransferase
NYE86_04350	COG1970	mechanosensitive ion channel activity
NYE86_04360	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NYE86_04375	COG3263	regulation of cellular component size
NYE86_04385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NYE86_04390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NYE86_04400	COG0315	cyclic pyranopterin monophosphate synthase activity
NYE86_04405	COG0521	Mo-molybdopterin cofactor biosynthetic process
NYE86_04410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NYE86_04425	COG0679	Auxin Efflux Carrier
NYE86_04430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NYE86_04440	COG2409	Drug exporters of the RND superfamily
NYE86_04450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NYE86_04475	COG2072	flavoprotein involved in K transport
NYE86_04480	COG2267	carboxylic ester hydrolase activity
NYE86_04485	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_04495	COG1515	deoxyribonuclease V activity
NYE86_04500	COG0793	Belongs to the peptidase S41A family
NYE86_04500	COG4946	Tricorn protease homolog
NYE86_04515	COG5297	Belongs to the glycosyl hydrolase family 6
NYE86_04585	COG0084	hydrolase, TatD family'
NYE86_04595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NYE86_04600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NYE86_04605	COG0488	(ABC) transporter
NYE86_04630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NYE86_04635	COG2197	response regulator
NYE86_04645	COG4106	trans-aconitate 2-methyltransferase activity
NYE86_04655	COG0193	aminoacyl-tRNA hydrolase activity
NYE86_04660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NYE86_04665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NYE86_04670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NYE86_04685	COG1309	transcriptional regulator
NYE86_04690	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NYE86_04695	COG4585	Histidine kinase
NYE86_04735	COG1136	(ABC) transporter
NYE86_04740	COG1136	(ABC) transporter
NYE86_04740	COG0577	efflux transmembrane transporter activity
NYE86_04750	COG0823	Involved in the tonB-independent uptake of proteins
NYE86_04775	COG0515	serine threonine protein kinase
NYE86_04775	COG2815	serine threonine protein kinase
NYE86_04800	COG2124	cytochrome p450
NYE86_04815	COG0148	phosphopyruvate hydratase activity
NYE86_04840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NYE86_04880	COG0183	Belongs to the thiolase family
NYE86_04885	COG2755	lipolytic protein G-D-S-L family
NYE86_04900	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_04905	COG2409	Drug exporters of the RND superfamily
NYE86_04930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NYE86_04935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NYE86_04945	COG1228	amidohydrolase
NYE86_04950	COG1191	sigma factor activity
NYE86_04965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYE86_04975	COG0745	RESPONSE REGULATOR receiver
NYE86_04980	COG2205	protein histidine kinase activity
NYE86_04995	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NYE86_05015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NYE86_05020	COG1316	TRANSCRIPTIONal
NYE86_05035	COG1316	TRANSCRIPTIONal
NYE86_05045	COG1316	TRANSCRIPTIONal
NYE86_05055	COG1316	TRANSCRIPTIONal
NYE86_05070	COG1316	TRANSCRIPTIONal
NYE86_05085	COG0778	Nitroreductase
NYE86_05085	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
NYE86_05090	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NYE86_05125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NYE86_05140	COG1482	cell wall glycoprotein biosynthetic process
NYE86_05150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NYE86_05185	COG0745	RESPONSE REGULATOR receiver
NYE86_05190	COG5000	phosphorelay sensor kinase activity
NYE86_05190	COG5002	protein histidine kinase activity
NYE86_05195	COG0823	Involved in the tonB-independent uptake of proteins
NYE86_05205	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NYE86_05210	COG2197	response regulator
NYE86_05215	COG3214	Protein conserved in bacteria
NYE86_05225	COG0653	protein targeting
NYE86_05245	COG2902	Dehydrogenase
NYE86_05290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NYE86_05315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NYE86_05320	COG1216	Glycosyl transferase, family 2
NYE86_05320	COG1442	glycosyl transferase family 8
NYE86_05325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NYE86_05340	COG0395	ABC-type sugar transport system, permease component
NYE86_05345	COG1175	transmembrane transport
NYE86_05355	COG1674	ftsk spoiiie
NYE86_05370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NYE86_05430	COG2884	Cell division ATP-binding protein ftsE
NYE86_05435	COG2177	Part of the ABC transporter FtsEX involved in
NYE86_05440	COG0793	Belongs to the peptidase S41A family
NYE86_05445	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NYE86_05455	COG2223	nitrite transmembrane transporter activity
NYE86_05470	COG3973	AAA domain
NYE86_05480	COG0776	regulation of translation
NYE86_05485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NYE86_05490	COG1678	Uncharacterized ACR, COG1678
NYE86_05505	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NYE86_05520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NYE86_05570	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NYE86_05575	COG0277	FAD linked oxidase domain protein
NYE86_05605	COG1335	isochorismatase
NYE86_05615	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NYE86_05645	COG1234	tRNA 3'-trailer cleavage
NYE86_05650	COG1263	PTS System
NYE86_05655	COG1263	PTS System
NYE86_05660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NYE86_05665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NYE86_05670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NYE86_05705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NYE86_05735	COG0604	alcohol dehydrogenase
NYE86_05745	COG2733	membrane
NYE86_05750	COG0179	Fumarylacetoacetate (FAA) hydrolase
NYE86_05755	COG4702	Belongs to the UPF0303 family
NYE86_05760	COG0673	inositol 2-dehydrogenase activity
NYE86_05790	COG0277	FAD linked oxidase domain protein
NYE86_05790	COG0247	lactate metabolic process
NYE86_05820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_05850	COG0406	alpha-ribazole phosphatase activity
NYE86_05895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NYE86_05895	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NYE86_05925	COG0745	RESPONSE REGULATOR receiver
NYE86_05935	COG3979	chitinase
NYE86_05945	COG0395	ABC-type sugar transport system, permease component
NYE86_05985	COG4733	cellulase activity
NYE86_05985	COG5297	Belongs to the glycosyl hydrolase family 6
NYE86_05990	COG0181	hydroxymethylbilane synthase activity
NYE86_06000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NYE86_06010	COG4977	sequence-specific DNA binding
NYE86_06015	COG0589	response to stress
NYE86_06020	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NYE86_06030	COG1960	acyl-CoA dehydrogenase activity
NYE86_06045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NYE86_06050	COG1309	transcriptional regulator
NYE86_06055	COG1960	acyl-CoA dehydrogenase activity
NYE86_06060	COG1946	Acyl-CoA thioesterase
NYE86_06065	COG4585	Histidine kinase
NYE86_06070	COG2197	response regulator
NYE86_06090	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_06160	COG0488	(ABC) transporter
NYE86_06195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NYE86_06215	COG2197	response regulator
NYE86_06290	COG1609	Transcriptional regulator
NYE86_06295	COG0673	inositol 2-dehydrogenase activity
NYE86_06310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NYE86_06335	COG2409	Drug exporters of the RND superfamily
NYE86_06350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NYE86_06360	COG1846	Transcriptional regulator
NYE86_06385	COG0629	single-stranded DNA binding
NYE86_06410	COG1136	(ABC) transporter
NYE86_06410	COG0577	efflux transmembrane transporter activity
NYE86_06430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NYE86_06450	COG0515	serine threonine protein kinase
NYE86_06460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NYE86_06475	COG1486	melibiose metabolic process
NYE86_06480	COG0395	ABC-type sugar transport system, permease component
NYE86_06485	COG1175	transmembrane transport
NYE86_06500	COG0668	transmembrane transport
NYE86_06540	COG1136	(ABC) transporter
NYE86_06540	COG4591	ABC-type transport system involved in lipoprotein release permease component
NYE86_06565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NYE86_06570	COG0346	lactoylglutathione lyase activity
NYE86_06590	COG4552	Acetyltransferase involved in intracellular survival and related
NYE86_06625	COG0544	peptidyl-prolyl cis-trans isomerase activity
NYE86_06630	COG0740	serine-type endopeptidase activity
NYE86_06635	COG0740	serine-type endopeptidase activity
NYE86_06640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NYE86_06655	COG0525	valine-tRNA ligase activity
NYE86_06660	COG0285	dihydrofolate synthase activity
NYE86_06670	COG0105	UTP biosynthetic process
NYE86_06675	COG1077	Cell shape determining protein MreB Mrl
NYE86_06695	COG0772	Belongs to the SEDS family
NYE86_06740	COG1530	ribonuclease E activity
NYE86_06745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NYE86_06750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NYE86_06755	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NYE86_06760	COG1216	Glycosyl transferase, family 2
NYE86_06765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NYE86_06765	COG0463	Glycosyl transferase, family 2
NYE86_06770	COG0438	transferase activity, transferring glycosyl groups
NYE86_06810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NYE86_06820	COG0463	Glycosyl transferase, family 2
NYE86_06835	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NYE86_06845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NYE86_06860	COG0501	Belongs to the peptidase M48B family
NYE86_06870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NYE86_06885	COG0588	phosphoglycerate mutase activity
NYE86_06900	COG0477	Major facilitator Superfamily
NYE86_06905	COG1902	pentaerythritol trinitrate reductase activity
NYE86_06945	COG0495	leucyl-tRNA aminoacylation
NYE86_06955	COG1307	EDD domain protein, DegV family
NYE86_06960	COG1555	photosystem II stabilization
NYE86_06995	COG0268	Binds directly to 16S ribosomal RNA
NYE86_07000	COG0481	GTPase activity
NYE86_07005	COG1022	Amp-dependent synthetase and ligase
NYE86_07030	COG1420	regulation of RNA biosynthetic process
NYE86_07035	COG0484	heat shock protein binding
NYE86_07080	COG0537	adenosine 5'-monophosphoramidase activity
NYE86_07085	COG1234	tRNA 3'-trailer cleavage
NYE86_07095	COG1486	melibiose metabolic process
NYE86_07100	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NYE86_07100	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NYE86_07110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NYE86_07145	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NYE86_07155	COG0477	Major facilitator Superfamily
NYE86_07165	COG3953	SLT domain
NYE86_07165	COG5280	Phage tail tape measure protein TP901
NYE86_07195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NYE86_07205	COG2409	Drug exporters of the RND superfamily
NYE86_07210	COG4585	Histidine kinase
NYE86_07215	COG2197	response regulator
NYE86_07220	COG1381	Involved in DNA repair and RecF pathway recombination
NYE86_07225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NYE86_07235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NYE86_07240	COG1121	(ABC) transporter
NYE86_07250	COG0423	glycine-tRNA ligase activity
NYE86_07260	COG0477	Major facilitator Superfamily
NYE86_07270	COG1309	transcriptional regulator
NYE86_07290	COG0574	Belongs to the PEP-utilizing enzyme family
NYE86_07290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NYE86_07300	COG1609	Transcriptional regulator
NYE86_07315	COG2146	nitrite reductase [NAD(P)H] activity
NYE86_07315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NYE86_07335	COG1802	Transcriptional regulator
NYE86_07340	COG2949	membrane
NYE86_07360	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NYE86_07375	COG0358	DNA primase activity
NYE86_07400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_07405	COG2814	Major facilitator Superfamily
NYE86_07415	COG0477	Major facilitator Superfamily
NYE86_07440	COG1070	Carbohydrate kinase
NYE86_07565	COG1940	carbohydrate kinase activity
NYE86_07565	COG1846	Transcriptional regulator
NYE86_07570	COG0673	inositol 2-dehydrogenase activity
NYE86_07605	COG1653	transport
NYE86_07610	COG1764	response to oxidative stress
NYE86_07615	COG2130	NADP-dependent
NYE86_07635	COG2837	iron assimilation
NYE86_07650	COG0477	Major facilitator Superfamily
NYE86_07670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYE86_07675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYE86_07680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYE86_07705	COG0789	Transcriptional regulator
NYE86_07710	COG0667	Aldo Keto reductase
NYE86_07725	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NYE86_07770	COG1358	cellular component organization or biogenesis
NYE86_07780	COG1072	(Pantothenic acid kinase))
NYE86_07810	COG1132	(ABC) transporter
NYE86_07815	COG1132	(ABC) transporter
NYE86_07820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NYE86_07835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NYE86_07840	COG0022	dehydrogenase e1 component
NYE86_07845	COG0508	dehydrogenase complex catalyzes the overall conversion of
NYE86_07850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYE86_07885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NYE86_07900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NYE86_07910	COG3409	Peptidoglycan-binding domain 1 protein
NYE86_07910	COG3773	Cell wall hydrolase
NYE86_07930	COG3845	ABC transporter
NYE86_07960	COG0515	serine threonine protein kinase
NYE86_07970	COG1132	(ABC) transporter
NYE86_07985	COG2197	response regulator
NYE86_07995	COG0300	oxidoreductase activity
NYE86_08000	COG1309	transcriptional regulator
NYE86_08005	COG0438	transferase activity, transferring glycosyl groups
NYE86_08010	COG2226	methyltransferase
NYE86_08035	COG0860	N-Acetylmuramoyl-L-alanine amidase
NYE86_08050	COG2197	response regulator
NYE86_08090	COG1131	(ABC) transporter
NYE86_08100	COG4585	Histidine kinase
NYE86_08115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NYE86_08120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NYE86_08135	COG0800	Aldolase
NYE86_08140	COG3022	response to hydroperoxide
NYE86_08175	COG1011	Hydrolase
NYE86_08195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NYE86_08250	COG1857	crispr-associated protein
NYE86_08270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NYE86_08290	COG0640	Transcriptional regulator
NYE86_08310	COG0697	spore germination
NYE86_08360	COG1846	Transcriptional regulator
NYE86_08370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NYE86_08370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NYE86_08390	COG3537	Alpha-1,2-mannosidase
NYE86_08395	COG3920	Histidine kinase
NYE86_08400	COG1940	carbohydrate kinase activity
NYE86_08435	COG2154	pterin-4-alpha-carbinolamine dehydratase
NYE86_08445	COG2814	Major facilitator Superfamily
NYE86_08455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NYE86_08460	COG3391	amine dehydrogenase activity
NYE86_08465	COG0726	polysaccharide deacetylase
NYE86_08480	COG0297	glycogen (starch) synthase activity
NYE86_08500	COG0438	transferase activity, transferring glycosyl groups
NYE86_08520	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NYE86_08525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYE86_08530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NYE86_08540	COG2801	Transposase and inactivated derivatives
NYE86_08540	COG3415	Transposase
NYE86_08545	COG0598	Magnesium transport protein CorA
NYE86_08575	COG1834	amidinotransferase
NYE86_08585	COG0604	alcohol dehydrogenase
NYE86_08595	COG1994	Peptidase M50
NYE86_08625	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NYE86_08630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NYE86_08635	COG0477	Major facilitator Superfamily
NYE86_08640	COG1309	transcriptional regulator
NYE86_08650	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NYE86_08650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NYE86_08655	COG0366	Alpha amylase catalytic
NYE86_08660	COG0395	ABC-type sugar transport system, permease component
NYE86_08665	COG1175	transmembrane transport
NYE86_08720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NYE86_08775	COG0174	glutamine synthetase
NYE86_08790	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_08810	COG3511	phospholipase C
NYE86_08830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NYE86_08840	COG1609	Transcriptional regulator
NYE86_08845	COG0366	Alpha amylase catalytic
NYE86_08850	COG3833	ABC-type maltose transport systems, permease component
NYE86_08855	COG1175	transmembrane transport
NYE86_08860	COG2182	Extracellular solute-binding protein
NYE86_08915	COG2304	oxidoreductase activity
NYE86_08925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NYE86_08975	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NYE86_08980	COG0321	lipoyl(octanoyl) transferase activity
NYE86_09005	COG0456	acetyltransferase
NYE86_09010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NYE86_09025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NYE86_09030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NYE86_09045	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NYE86_09060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NYE86_09085	COG4585	Histidine kinase
NYE86_09095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NYE86_09115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NYE86_09125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NYE86_09130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NYE86_09140	COG1376	ErfK ybiS ycfS ynhG family protein
NYE86_09150	COG1845	cytochrome c oxidase, subunit III
NYE86_09155	COG2010	Cytochrome c
NYE86_09160	COG0723	plastoquinol--plastocyanin reductase activity
NYE86_09165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NYE86_09170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NYE86_09175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NYE86_09185	COG0705	Rhomboid family
NYE86_09200	COG0791	NLP P60 protein
NYE86_09200	COG1388	LysM domain
NYE86_09200	COG3103	Sh3 type 3 domain protein
NYE86_09220	COG0501	Belongs to the peptidase M48B family
NYE86_09240	COG1940	carbohydrate kinase activity
NYE86_09285	COG4585	Histidine kinase
NYE86_09290	COG2197	response regulator
NYE86_09295	COG0205	6-phosphofructokinase activity
NYE86_09300	COG0572	uridine kinase
NYE86_09315	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NYE86_09325	COG2193	ferroxidase activity
NYE86_09330	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NYE86_09340	COG2022	thiamine diphosphate biosynthetic process
NYE86_09350	COG2022	thiamine diphosphate biosynthetic process
NYE86_09350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NYE86_09365	COG0352	thiamine-phosphate diphosphorylase activity
NYE86_09405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NYE86_09425	COG0714	Associated with various cellular activities
NYE86_09435	COG2001	Belongs to the MraZ family
NYE86_09440	COG0275	rRNA processing
NYE86_09450	COG0768	penicillin binding
NYE86_09455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NYE86_09465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NYE86_09470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NYE86_09480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NYE86_09485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NYE86_09490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NYE86_09495	COG1496	oxidoreductase activity
NYE86_09505	COG1799	cell septum assembly
NYE86_09515	COG3599	regulation of cell shape
NYE86_09520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NYE86_09530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NYE86_09540	COG2153	protein acetylation
NYE86_09565	COG0587	DNA-directed DNA polymerase activity
NYE86_09575	COG1432	Conserved Protein
NYE86_09595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NYE86_09610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NYE86_09615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NYE86_09620	COG0131	Imidazoleglycerol-phosphate dehydratase
NYE86_09630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NYE86_09635	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NYE86_09640	COG0251	oxidation-reduction process
NYE86_09645	COG0107	imidazoleglycerol-phosphate synthase activity
NYE86_09675	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NYE86_09705	COG0134	indole-3-glycerol-phosphate synthase activity
NYE86_09710	COG0133	tryptophan synthase activity
NYE86_09715	COG0159	tryptophan synthase activity
NYE86_09725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NYE86_09735	COG0067	glutamate synthase
NYE86_09735	COG0069	glutamate synthase activity
NYE86_09735	COG0070	glutamate synthase
NYE86_09765	COG0737	Belongs to the 5'-nucleotidase family
NYE86_09815	COG2050	protein possibly involved in aromatic compounds catabolism
NYE86_09830	COG1643	Atp-dependent helicase
NYE86_09840	COG0539	negative regulation of cytoplasmic translation
NYE86_09850	COG0237	dephospho-CoA kinase activity
NYE86_09860	COG0330	HflC and HflK could
NYE86_09870	COG0556	nucleotide-excision repair
NYE86_09895	COG2378	regulation of single-species biofilm formation
NYE86_09920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NYE86_09930	COG0322	excinuclease ABC activity
NYE86_09935	COG1660	Displays ATPase and GTPase activities
NYE86_09940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NYE86_09945	COG1481	regulation of sporulation
NYE86_09950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NYE86_09955	COG0126	phosphoglycerate kinase activity
NYE86_09960	COG0149	triose-phosphate isomerase activity
NYE86_09965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NYE86_09975	COG0166	Belongs to the GPI family
NYE86_09980	COG0363	glucosamine-6-phosphate deaminase activity
NYE86_09995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NYE86_10005	COG0109	protoheme IX farnesyltransferase activity
NYE86_10030	COG1131	(ABC) transporter
NYE86_10045	COG0719	Fe-S assembly protein
NYE86_10055	COG0396	ATPase activity
NYE86_10060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NYE86_10065	COG0822	iron-sulfur transferase activity
NYE86_10080	COG2171	N-acyltransferase activity
NYE86_10125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYE86_10130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NYE86_10155	COG1414	Transcriptional regulator
NYE86_10185	COG4977	sequence-specific DNA binding
NYE86_10200	COG0515	serine threonine protein kinase
NYE86_10210	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NYE86_10240	COG1797	cobyrinic acid a,c-diamide synthase activity
NYE86_10260	COG1492	cobalamin metabolic process
NYE86_10280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NYE86_10280	COG0723	plastoquinol--plastocyanin reductase activity
NYE86_10285	COG0235	Class ii aldolase
NYE86_10300	COG0488	(ABC) transporter
NYE86_10310	COG1024	Enoyl-CoA hydratase
NYE86_10365	COG3387	PFAM Glycoside hydrolase 15-related
NYE86_10395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NYE86_10410	COG2261	transglycosylase associated protein
NYE86_10415	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NYE86_10450	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_10455	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NYE86_10460	COG2186	Transcriptional regulator
NYE86_10465	COG2807	transmembrane transport
NYE86_10485	COG0560	Phosphoserine phosphatase
NYE86_10485	COG3830	Belongs to the UPF0237 family
NYE86_10490	COG0842	Transport permease protein
NYE86_10490	COG1131	(ABC) transporter
NYE86_10490	COG1716	ATPase activity
NYE86_10500	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NYE86_10505	COG4221	oxidoreductase activity
NYE86_10510	COG4585	Histidine kinase
NYE86_10515	COG2197	response regulator
NYE86_10525	COG1119	ATPase activity
NYE86_10550	COG1881	PFAM PEBP family protein
NYE86_10565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NYE86_10600	COG0647	UMP catabolic process
NYE86_10625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NYE86_10630	COG0497	DNA recombination
NYE86_10645	COG3387	PFAM Glycoside hydrolase 15-related
NYE86_10650	COG0504	CTP synthase activity
NYE86_10655	COG0494	nUDIX hydrolase
NYE86_10690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NYE86_10695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NYE86_10715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NYE86_10725	COG1160	GTP binding
NYE86_10745	COG0438	transferase activity, transferring glycosyl groups
NYE86_10755	COG0671	phosphoesterase, PA-phosphatase related
NYE86_10760	COG0477	Major facilitator Superfamily
NYE86_10765	COG1960	acyl-CoA dehydrogenase activity
NYE86_10770	COG2409	Drug exporters of the RND superfamily
NYE86_10775	COG1799	cell septum assembly
NYE86_10800	COG3467	pyridoxamine 5'-phosphate
NYE86_10830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NYE86_10845	COG1846	Transcriptional regulator
NYE86_10850	COG1725	Transcriptional regulator
NYE86_10870	COG2188	Transcriptional regulator
NYE86_10875	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NYE86_10885	COG0477	Major facilitator Superfamily
NYE86_10895	COG1309	transcriptional regulator
NYE86_10900	COG3383	formate dehydrogenase (NAD+) activity
NYE86_10925	COG1960	acyl-CoA dehydrogenase activity
NYE86_10950	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NYE86_10965	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_10970	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_10975	COG3226	Transcriptional regulator
NYE86_10995	COG4948	Mandelate Racemase Muconate Lactonizing
NYE86_11005	COG3265	gluconokinase activity
NYE86_11010	COG1802	Transcriptional regulator
NYE86_11020	COG2149	membrane
NYE86_11040	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NYE86_11060	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NYE86_11085	COG0492	ferredoxin-NADP+ reductase activity
NYE86_11100	COG0477	Major facilitator Superfamily
NYE86_11125	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NYE86_11135	COG0667	Aldo Keto reductase
NYE86_11190	COG0366	Alpha amylase catalytic
NYE86_11195	COG3281	Trehalose synthase
NYE86_11215	COG4175	Glycine betaine
NYE86_11215	COG3448	diguanylate cyclase activity
NYE86_11220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NYE86_11225	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NYE86_11225	COG1672	PFAM Archaeal ATPase
NYE86_11265	COG2132	Multicopper oxidase
NYE86_11280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NYE86_11315	COG0667	Aldo Keto reductase
NYE86_11320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_11330	COG0588	phosphoglycerate mutase activity
NYE86_11345	COG0215	cysteine-tRNA ligase activity
NYE86_11370	COG4948	Mandelate Racemase Muconate Lactonizing
NYE86_11375	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_11385	COG1129	ABC transporter
NYE86_11390	COG4214	carbohydrate transport
NYE86_11405	COG2186	Transcriptional regulator
NYE86_11425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NYE86_11430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NYE86_11435	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NYE86_11445	COG0646	methionine synthase
NYE86_11445	COG1410	methionine synthase
NYE86_11460	COG0601	transmembrane transport
NYE86_11465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NYE86_11475	COG4608	Belongs to the ABC transporter superfamily
NYE86_11480	COG4166	transmembrane transport
NYE86_11485	COG2197	response regulator
NYE86_11495	COG0517	IMP dehydrogenase activity
NYE86_11495	COG1994	Peptidase M50
NYE86_11515	COG1222	aaa ATPase
NYE86_11520	COG4122	O-methyltransferase activity
NYE86_11530	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NYE86_11535	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NYE86_11540	COG1609	Transcriptional regulator
NYE86_11550	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NYE86_11555	COG0545	Peptidyl-prolyl cis-trans isomerase
NYE86_11570	COG2378	regulation of single-species biofilm formation
NYE86_11585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NYE86_11590	COG0805	protein transport
NYE86_11685	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NYE86_11705	COG2188	Transcriptional regulator
NYE86_11710	COG0726	polysaccharide deacetylase
NYE86_11715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NYE86_11760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NYE86_11770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NYE86_11775	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NYE86_11780	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NYE86_11785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NYE86_11790	COG5002	protein histidine kinase activity
NYE86_11795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NYE86_11800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NYE86_11800	COG0072	phenylalanine-tRNA ligase activity
NYE86_11825	COG1134	teichoic acid transport
NYE86_11840	COG1649	PFAM Uncharacterised BCR, COG1649
NYE86_11860	COG3903	Transcriptional regulator
NYE86_11860	COG3629	intracellular signal transduction
NYE86_11885	COG2813	Specifically methylates the guanine in position
NYE86_11910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NYE86_11915	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NYE86_11920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NYE86_11925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NYE86_11930	COG1438	arginine binding
NYE86_11935	COG0137	argininosuccinate synthase activity
NYE86_11940	COG0165	Argininosuccinate lyase
NYE86_11945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NYE86_11950	COG0204	Acyl-transferase
NYE86_11950	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_11985	COG2011	ABC-type metal ion transport system permease component
NYE86_11990	COG1464	Belongs to the NlpA lipoprotein family
NYE86_12010	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NYE86_12015	COG1648	precorrin-2 dehydrogenase activity
NYE86_12015	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NYE86_12040	COG1960	acyl-CoA dehydrogenase activity
NYE86_12045	COG1960	acyl-CoA dehydrogenase activity
NYE86_12055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NYE86_12060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NYE86_12165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NYE86_12170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NYE86_12190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NYE86_12195	COG1560	Kdo2-lipid A biosynthetic process
NYE86_12200	COG0438	transferase activity, transferring glycosyl groups
NYE86_12210	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NYE86_12215	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NYE86_12220	COG0217	transcriptional regulatory protein
NYE86_12225	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NYE86_12230	COG0632	four-way junction helicase activity
NYE86_12235	COG2255	four-way junction helicase activity
NYE86_12245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NYE86_12250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NYE86_12255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NYE86_12260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NYE86_12265	COG1196	nuclear chromosome segregation
NYE86_12270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NYE86_12280	COG0124	histidyl-tRNA synthetase
NYE86_12295	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NYE86_12315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NYE86_12320	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NYE86_12330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NYE86_12335	COG0739	heme binding
NYE86_12340	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NYE86_12345	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NYE86_12350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NYE86_12355	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NYE86_12365	COG0006	proline dipeptidase activity
NYE86_12370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NYE86_12375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NYE86_12385	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NYE86_12395	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NYE86_12400	COG0540	Belongs to the ATCase OTCase family
NYE86_12405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NYE86_12415	COG0505	Belongs to the CarA family
NYE86_12420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NYE86_12425	COG0167	dihydroorotate dehydrogenase activity
NYE86_12430	COG0284	orotidine-5'-phosphate decarboxylase activity
NYE86_12445	COG1758	RNA polymerase activity
NYE86_12455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NYE86_12470	COG0242	peptide deformylase activity
NYE86_12475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NYE86_12485	COG2409	Drug exporters of the RND superfamily
NYE86_12490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NYE86_12495	COG2390	Transcriptional regulator
NYE86_12520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NYE86_12540	COG2233	PERMEase
NYE86_12545	COG2223	nitrite transmembrane transporter activity
NYE86_12550	COG1940	carbohydrate kinase activity
NYE86_12565	COG3201	nicotinamide mononucleotide transporter
NYE86_12570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NYE86_12570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NYE86_12575	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NYE86_12580	COG0140	phosphoribosyl-ATP diphosphatase activity
NYE86_12585	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NYE86_12610	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NYE86_12610	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NYE86_12625	COG3469	chitinase activity
NYE86_12635	COG3300	MHYT domain
NYE86_12635	COG5001	Diguanylate cyclase
NYE86_12650	COG1960	acyl-CoA dehydrogenase activity
NYE86_12660	COG0277	FAD linked oxidase domain protein
NYE86_12680	COG1216	Glycosyl transferase, family 2
NYE86_12700	COG2364	Membrane
NYE86_12705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYE86_12755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NYE86_12765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_12775	COG2801	Transposase and inactivated derivatives
NYE86_12775	COG3415	Transposase
NYE86_12785	COG0667	Aldo Keto reductase
NYE86_12815	COG3979	chitinase
NYE86_12820	COG1968	undecaprenyl-diphosphatase activity
NYE86_12830	COG0673	inositol 2-dehydrogenase activity
NYE86_12840	COG1082	Xylose isomerase domain protein TIM barrel
NYE86_12845	COG0673	inositol 2-dehydrogenase activity
NYE86_12850	COG1940	carbohydrate kinase activity
NYE86_12870	COG1609	Transcriptional regulator
NYE86_12875	COG1172	Belongs to the binding-protein-dependent transport system permease family
NYE86_12885	COG1129	ABC transporter
NYE86_12890	COG1879	ABC-type sugar transport system periplasmic component
NYE86_12920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NYE86_12925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYE86_12940	COG0438	transferase activity, transferring glycosyl groups
NYE86_12975	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_12995	COG3979	chitinase
NYE86_13005	COG2814	Major facilitator Superfamily
NYE86_13015	COG0477	Major facilitator Superfamily
NYE86_13025	COG1132	(ABC) transporter
NYE86_13050	COG0477	Major facilitator Superfamily
NYE86_13055	COG3012	SEC-C Motif Domain Protein
NYE86_13065	COG1793	dna ligase
NYE86_13090	COG2226	methyltransferase
NYE86_13105	COG3511	phospholipase C
NYE86_13130	COG5297	Belongs to the glycosyl hydrolase family 6
NYE86_13145	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_13150	COG4941	Belongs to the sigma-70 factor family
NYE86_13155	COG3795	YCII-related domain
NYE86_13160	COG3619	membrane
NYE86_13165	COG2271	Major facilitator Superfamily
NYE86_13170	COG1609	Transcriptional regulator
NYE86_13200	COG1191	sigma factor activity
NYE86_13205	COG3458	cephalosporin-C deacetylase activity
NYE86_13215	COG0297	glycogen (starch) synthase activity
NYE86_13220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NYE86_13225	COG3537	Alpha-1,2-mannosidase
NYE86_13245	COG1609	Transcriptional regulator
NYE86_13250	COG0656	L-ascorbic acid biosynthetic process
NYE86_13290	COG1309	transcriptional regulator
NYE86_13315	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_13355	COG1755	Isoprenylcysteine carboxyl methyltransferase
NYE86_13375	COG1609	Transcriptional regulator
NYE86_13390	COG4213	ABC transporter substrate-binding protein
NYE86_13400	COG3275	phosphorelay sensor kinase activity
NYE86_13405	COG3279	Response regulator of the LytR AlgR family
NYE86_13415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NYE86_13420	COG1584	GPR1 FUN34 yaaH family protein
NYE86_13425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NYE86_13435	COG0395	ABC-type sugar transport system, permease component
NYE86_13440	COG1175	transmembrane transport
NYE86_13455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYE86_13460	COG1309	transcriptional regulator
NYE86_13490	COG1595	DNA-templated transcription, initiation
NYE86_13495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NYE86_13530	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NYE86_13535	COG0714	Associated with various cellular activities
NYE86_13565	COG1175	transmembrane transport
NYE86_13570	COG0395	ABC-type sugar transport system, permease component
NYE86_13580	COG1595	DNA-templated transcription, initiation
NYE86_13595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NYE86_13625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NYE86_13645	COG1609	Transcriptional regulator
NYE86_13665	COG3469	chitinase activity
NYE86_13675	COG2205	protein histidine kinase activity
NYE86_13695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYE86_13705	COG0372	Belongs to the citrate synthase family
NYE86_13715	COG0501	Belongs to the peptidase M48B family
NYE86_13740	COG0477	Major facilitator Superfamily
NYE86_13775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NYE86_13780	COG0183	Belongs to the thiolase family
NYE86_13805	COG2183	response to ionizing radiation
NYE86_13825	COG0366	Alpha amylase catalytic
NYE86_13825	COG1874	Beta-galactosidase
NYE86_13830	COG0446	pyridine nucleotide-disulphide oxidoreductase
NYE86_13850	COG1742	UPF0060 membrane protein
NYE86_13875	COG1132	(ABC) transporter
NYE86_13880	COG1132	(ABC) transporter
NYE86_13895	COG1846	Transcriptional regulator
NYE86_13900	COG1132	(ABC) transporter
NYE86_13905	COG1556	Lactate utilization protein
NYE86_13915	COG0247	lactate metabolic process
NYE86_13925	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_13935	COG1793	dna ligase
NYE86_13950	COG4977	sequence-specific DNA binding
NYE86_13965	COG2706	6-phosphogluconolactonase activity
NYE86_13985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NYE86_13995	COG1132	(ABC) transporter
NYE86_14010	COG3903	Transcriptional regulator
NYE86_14010	COG3629	intracellular signal transduction
NYE86_14020	COG1309	transcriptional regulator
NYE86_14045	COG0584	glycerophosphoryl diester phosphodiesterase
NYE86_14090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NYE86_14110	COG0477	Major facilitator Superfamily
NYE86_14120	COG1660	Displays ATPase and GTPase activities
NYE86_14145	COG4585	Histidine kinase
NYE86_14150	COG2197	response regulator
NYE86_14170	COG0738	Major facilitator superfamily
NYE86_14175	COG1940	carbohydrate kinase activity
NYE86_14185	COG1136	(ABC) transporter
NYE86_14200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYE86_14225	COG1349	DNA-binding transcription factor activity
NYE86_14260	COG1215	transferase activity, transferring glycosyl groups
NYE86_14265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NYE86_14290	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NYE86_14300	COG2376	Dihydroxyacetone kinase
NYE86_14315	COG0596	Alpha beta hydrolase
NYE86_14340	COG0745	RESPONSE REGULATOR receiver
NYE86_14345	COG2205	protein histidine kinase activity
NYE86_14350	COG1335	isochorismatase
NYE86_14375	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NYE86_14375	COG1672	PFAM Archaeal ATPase
NYE86_14385	COG0510	thiamine kinase activity
NYE86_14410	COG0438	transferase activity, transferring glycosyl groups
NYE86_14420	COG1984	allophanate hydrolase subunit 2
NYE86_14425	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NYE86_14430	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NYE86_14460	COG2018	Roadblock/LC7 domain
NYE86_14475	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NYE86_14480	COG0494	nUDIX hydrolase
NYE86_14500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NYE86_14505	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NYE86_14520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NYE86_14525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYE86_14540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NYE86_14570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NYE86_14610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NYE86_14620	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NYE86_14620	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NYE86_14645	COG0384	phenazine biosynthesis protein PhzF
NYE86_14655	COG4106	trans-aconitate 2-methyltransferase activity
NYE86_14665	COG0346	lactoylglutathione lyase activity
NYE86_14670	COG4977	sequence-specific DNA binding
NYE86_14675	COG1695	Transcriptional regulator
NYE86_14685	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_14705	COG0697	spore germination
NYE86_14720	COG0697	spore germination
NYE86_14755	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NYE86_14775	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NYE86_14810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NYE86_14820	COG1116	anion transmembrane transporter activity
NYE86_14825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_14835	COG0604	alcohol dehydrogenase
NYE86_14835	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_14835	COG3321	synthase
NYE86_14845	COG1309	transcriptional regulator
NYE86_14855	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NYE86_14860	COG3285	dna ligase
NYE86_14860	COG1793	dna ligase
NYE86_14870	COG1846	Transcriptional regulator
NYE86_14870	COG1940	carbohydrate kinase activity
NYE86_14935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NYE86_14940	COG0583	DNA-binding transcription factor activity
NYE86_14945	COG1349	DNA-binding transcription factor activity
NYE86_14980	COG2226	methyltransferase
NYE86_15010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYE86_15020	COG0662	Cupin 2, conserved barrel domain protein
NYE86_15035	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_15040	COG0395	ABC-type sugar transport system, permease component
NYE86_15045	COG1175	transmembrane transport
NYE86_15080	COG2197	response regulator
NYE86_15085	COG4585	Histidine kinase
NYE86_15090	COG1131	(ABC) transporter
NYE86_15145	COG3833	ABC-type maltose transport systems, permease component
NYE86_15150	COG1175	transmembrane transport
NYE86_15160	COG1940	carbohydrate kinase activity
NYE86_15165	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NYE86_15180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NYE86_15185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NYE86_15205	COG1397	ADP-ribosylglycohydrolase
NYE86_15220	COG1175	transmembrane transport
NYE86_15230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NYE86_15240	COG2186	Transcriptional regulator
NYE86_15265	COG3795	YCII-related domain
NYE86_15290	COG1556	Lactate utilization protein
NYE86_15295	COG1139	Iron-sulfur cluster binding protein
NYE86_15305	COG1070	Carbohydrate kinase
NYE86_15310	COG3347	Dehydrogenase
NYE86_15310	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_15315	COG4952	isomerase
NYE86_15320	COG1129	ABC transporter
NYE86_15325	COG1172	Belongs to the binding-protein-dependent transport system permease family
NYE86_15345	COG1609	Transcriptional regulator
NYE86_15360	COG0596	Alpha beta hydrolase
NYE86_15375	COG2208	phosphoserine phosphatase activity
NYE86_15375	COG2770	Histidine kinase
NYE86_15390	COG3795	YCII-related domain
NYE86_15395	COG4941	Belongs to the sigma-70 factor family
NYE86_15430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NYE86_15435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NYE86_15440	COG0477	Major facilitator Superfamily
NYE86_15465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYE86_15510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYE86_15520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYE86_15545	COG2124	cytochrome p450
NYE86_15555	COG0702	epimerase
NYE86_15565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYE86_15590	COG3795	YCII-related domain
NYE86_15605	COG0583	DNA-binding transcription factor activity
NYE86_15620	COG1846	Transcriptional regulator
NYE86_15645	COG3693	PFAM glycoside hydrolase, family 10
NYE86_15780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NYE86_15790	COG2814	Major facilitator Superfamily
NYE86_15795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NYE86_15830	COG0110	maltose O-acetyltransferase activity
NYE86_15840	COG1832	CoA-binding protein
NYE86_15845	COG1739	Uncharacterized protein family UPF0029
NYE86_15850	COG4948	Mandelate Racemase Muconate Lactonizing
NYE86_15855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NYE86_15860	COG0420	3'-5' exonuclease activity
NYE86_15870	COG0419	ATPase involved in DNA repair
NYE86_15875	COG1522	sequence-specific DNA binding
NYE86_15900	COG0626	cystathionine gamma-synthase activity
NYE86_15910	COG0745	RESPONSE REGULATOR receiver
NYE86_15920	COG0475	glutathione-regulated potassium exporter activity
NYE86_15925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NYE86_15940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYE86_15965	COG0477	Major facilitator Superfamily
NYE86_16020	COG0477	Major facilitator Superfamily
NYE86_16025	COG0431	NADPH-dependent FMN reductase
NYE86_16055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYE86_16065	COG2252	PERMEase
NYE86_16070	COG1595	DNA-templated transcription, initiation
NYE86_16075	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_16080	COG2188	Transcriptional regulator
NYE86_16085	COG1940	carbohydrate kinase activity
NYE86_16095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NYE86_16110	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_16145	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NYE86_16150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NYE86_16155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NYE86_16160	COG0156	8-amino-7-oxononanoate synthase activity
NYE86_16190	COG0740	serine-type endopeptidase activity
NYE86_16200	COG0831	urea catabolic process
NYE86_16205	COG0832	Belongs to the urease beta subunit family
NYE86_16210	COG0804	urea catabolic process
NYE86_16220	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NYE86_16225	COG0829	nickel cation binding
NYE86_16230	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NYE86_16240	COG1120	ATPase activity
NYE86_16245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYE86_16250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NYE86_16260	COG3251	PFAM MbtH domain protein
NYE86_16265	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NYE86_16270	COG1132	(ABC) transporter
NYE86_16285	COG0504	CTP synthase activity
NYE86_16300	COG0204	Acyl-transferase
NYE86_16310	COG0205	6-phosphofructokinase activity
NYE86_16315	COG3442	glutamine amidotransferase
NYE86_16330	COG1960	acyl-CoA dehydrogenase activity
NYE86_16385	COG0714	Associated with various cellular activities
NYE86_16400	COG3250	beta-galactosidase activity
NYE86_16415	COG1175	transmembrane transport
NYE86_16425	COG2890	protein-(glutamine-N5) methyltransferase activity
NYE86_16440	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NYE86_16485	COG1131	(ABC) transporter
NYE86_16495	COG4585	Histidine kinase
NYE86_16500	COG2197	response regulator
NYE86_16510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NYE86_16510	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NYE86_16520	COG2268	Band 7 protein
NYE86_16525	COG1302	Protein conserved in bacteria
NYE86_16720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NYE86_16900	COG2378	regulation of single-species biofilm formation
NYE86_16905	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_16935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NYE86_16940	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_17000	COG1960	acyl-CoA dehydrogenase activity
NYE86_17005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYE86_17010	COG2197	response regulator
NYE86_17015	COG0475	glutathione-regulated potassium exporter activity
NYE86_17020	COG2197	response regulator
NYE86_17075	COG1404	Belongs to the peptidase S8 family
NYE86_17085	COG2814	Major facilitator Superfamily
NYE86_17155	COG0406	alpha-ribazole phosphatase activity
NYE86_17180	COG3903	Transcriptional regulator
NYE86_17180	COG3629	intracellular signal transduction
NYE86_17190	COG0590	tRNA wobble adenosine to inosine editing
NYE86_17265	COG1720	tRNA m6t6A37 methyltransferase activity
NYE86_17270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NYE86_17280	COG1309	transcriptional regulator
NYE86_17330	COG1120	ATPase activity
NYE86_17345	COG0667	Aldo Keto reductase
NYE86_17355	COG1404	Belongs to the peptidase S8 family
NYE86_17360	COG2319	Wd-40 repeat
NYE86_17360	COG4249	Peptidase C14 caspase catalytic subunit p20
NYE86_17380	COG3321	synthase
NYE86_17380	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_17380	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_17380	COG0300	oxidoreductase activity
NYE86_17380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYE86_17390	COG0667	Aldo Keto reductase
NYE86_17395	COG1017	nitric oxide dioxygenase activity
NYE86_17395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NYE86_17410	COG1404	Belongs to the peptidase S8 family
NYE86_17420	COG1902	pentaerythritol trinitrate reductase activity
NYE86_17425	COG1309	transcriptional regulator
NYE86_17450	COG2815	serine threonine protein kinase
NYE86_17450	COG0515	serine threonine protein kinase
NYE86_17460	COG4221	oxidoreductase activity
NYE86_17470	COG1309	transcriptional regulator
NYE86_17480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_17495	COG0577	efflux transmembrane transporter activity
NYE86_17495	COG1136	(ABC) transporter
NYE86_17500	COG1136	(ABC) transporter
NYE86_17500	COG0577	efflux transmembrane transporter activity
NYE86_17515	COG0745	RESPONSE REGULATOR receiver
NYE86_17520	COG2205	protein histidine kinase activity
NYE86_17525	COG1619	proteins homologs of microcin C7 resistance protein MccF
NYE86_17545	COG0596	Alpha beta hydrolase
NYE86_17550	COG3548	integral membrane protein
NYE86_17605	COG1309	transcriptional regulator
NYE86_17610	COG4941	Belongs to the sigma-70 factor family
NYE86_17645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NYE86_17670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NYE86_17675	COG1121	(ABC) transporter
NYE86_17680	COG0803	Belongs to the bacterial solute-binding protein 9 family
NYE86_17690	COG2226	methyltransferase
NYE86_17715	COG1595	DNA-templated transcription, initiation
NYE86_17725	COG0456	acetyltransferase
NYE86_17740	COG0254	rRNA binding
NYE86_17745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NYE86_17765	COG0667	Aldo Keto reductase
NYE86_17780	COG0583	DNA-binding transcription factor activity
NYE86_17820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NYE86_17830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NYE86_17835	COG0300	oxidoreductase activity
NYE86_17855	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NYE86_17860	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NYE86_17865	COG1733	regulation of RNA biosynthetic process
NYE86_17880	COG0596	Alpha beta hydrolase
NYE86_17890	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_17905	COG0667	Aldo Keto reductase
NYE86_17950	COG2226	methyltransferase
NYE86_17955	COG0330	HflC and HflK could
NYE86_17965	COG0667	Aldo Keto reductase
NYE86_17985	COG1174	glycine betaine transport
NYE86_17990	COG1174	glycine betaine transport
NYE86_18005	COG1609	Transcriptional regulator
NYE86_18015	COG0395	ABC-type sugar transport system, permease component
NYE86_18035	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_18055	COG2132	Multicopper oxidase
NYE86_18075	COG1982	Orn Lys Arg decarboxylase major
NYE86_18080	COG0300	oxidoreductase activity
NYE86_18110	COG0009	L-threonylcarbamoyladenylate synthase
NYE86_18120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NYE86_18125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NYE86_18135	COG2770	Histidine kinase
NYE86_18135	COG2208	phosphoserine phosphatase activity
NYE86_18140	COG0456	acetyltransferase
NYE86_18150	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_18210	COG1335	isochorismatase
NYE86_18215	COG2146	nitrite reductase [NAD(P)H] activity
NYE86_18250	COG2890	protein-(glutamine-N5) methyltransferase activity
NYE86_18255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_18260	COG0247	lactate metabolic process
NYE86_18260	COG0277	FAD linked oxidase domain protein
NYE86_18265	COG0028	Belongs to the TPP enzyme family
NYE86_18270	COG4948	Mandelate Racemase Muconate Lactonizing
NYE86_18280	COG0181	hydroxymethylbilane synthase activity
NYE86_18285	COG1091	dTDP-4-dehydrorhamnose reductase activity
NYE86_18290	COG4948	Mandelate Racemase Muconate Lactonizing
NYE86_18385	COG1595	DNA-templated transcription, initiation
NYE86_18405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NYE86_18475	COG3250	beta-galactosidase activity
NYE86_18485	COG1609	Transcriptional regulator
NYE86_18495	COG1653	transport
NYE86_18500	COG1175	transmembrane transport
NYE86_18505	COG0395	ABC-type sugar transport system, permease component
NYE86_18510	COG3458	cephalosporin-C deacetylase activity
NYE86_18535	COG1233	COG1233 Phytoene dehydrogenase and related
NYE86_18555	COG4209	transmembrane transport
NYE86_18560	COG0395	ABC-type sugar transport system, permease component
NYE86_18575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NYE86_18605	COG4257	antibiotic catabolic process
NYE86_18650	COG0583	DNA-binding transcription factor activity
NYE86_18680	COG2409	Drug exporters of the RND superfamily
NYE86_18685	COG1937	Protein conserved in bacteria
NYE86_18705	COG0516	GMP reductase activity
NYE86_18705	COG0517	IMP dehydrogenase activity
NYE86_18710	COG3509	depolymerase
NYE86_18815	COG0038	chloride channel
NYE86_18825	COG0659	secondary active sulfate transmembrane transporter activity
NYE86_18845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NYE86_18850	COG1595	DNA-templated transcription, initiation
NYE86_18860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NYE86_18860	COG0512	Glutamine amidotransferase of anthranilate synthase
NYE86_18925	COG0395	ABC-type sugar transport system, permease component
NYE86_18950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NYE86_18955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NYE86_18960	COG2080	2 iron, 2 sulfur cluster binding
NYE86_18985	COG2755	lipolytic protein G-D-S-L family
NYE86_18985	COG0657	acetylesterase activity
NYE86_19000	COG3507	Belongs to the glycosyl hydrolase 43 family
NYE86_19015	COG1653	transport
NYE86_19035	COG1609	Transcriptional regulator
NYE86_19090	COG0110	maltose O-acetyltransferase activity
NYE86_19115	COG0384	phenazine biosynthesis protein PhzF
NYE86_19175	COG2274	protein secretion by the type I secretion system
NYE86_19185	COG2837	iron assimilation
NYE86_19215	COG1595	DNA-templated transcription, initiation
NYE86_19245	COG0515	serine threonine protein kinase
NYE86_19245	COG2815	serine threonine protein kinase
NYE86_19265	COG0443	Heat shock 70 kDa protein
NYE86_19280	COG3866	Pectate lyase
NYE86_19300	COG0395	ABC-type sugar transport system, permease component
NYE86_19320	COG1802	Transcriptional regulator
NYE86_19325	COG0328	RNA-DNA hybrid ribonuclease activity
NYE86_19385	COG1796	DNA polymerase
NYE86_19385	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NYE86_19390	COG3409	Peptidoglycan-binding domain 1 protein
NYE86_19390	COG3757	hydrolase, family 25
NYE86_19400	COG0586	Pfam SNARE associated Golgi protein
NYE86_19410	COG2326	polyphosphate kinase activity
NYE86_19425	COG0300	oxidoreductase activity
NYE86_19440	COG0657	acetylesterase activity
NYE86_19470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NYE86_19490	COG1501	Belongs to the glycosyl hydrolase 31 family
NYE86_19500	COG2409	Drug exporters of the RND superfamily
NYE86_19510	COG3845	ABC transporter
NYE86_19540	COG3693	PFAM glycoside hydrolase, family 10
NYE86_19565	COG0702	epimerase
NYE86_19595	COG0596	Alpha beta hydrolase
NYE86_19600	COG1846	Transcriptional regulator
NYE86_19605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NYE86_19610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NYE86_19625	COG1846	Transcriptional regulator
NYE86_19660	COG1309	transcriptional regulator
NYE86_19665	COG0667	Aldo Keto reductase
NYE86_19715	COG1175	transmembrane transport
NYE86_19720	COG0395	ABC-type sugar transport system, permease component
NYE86_19740	COG3135	benzoate transporter
NYE86_19745	COG1609	Transcriptional regulator
NYE86_19750	COG0477	Major facilitator Superfamily
NYE86_19780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NYE86_19785	COG1053	succinate dehydrogenase
NYE86_19795	COG0583	DNA-binding transcription factor activity
NYE86_19805	COG1733	regulation of RNA biosynthetic process
NYE86_19815	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NYE86_19835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NYE86_19840	COG2151	metal-sulfur cluster biosynthetic enzyme
NYE86_19845	COG3396	Phenylacetate-CoA oxygenase
NYE86_19850	COG3460	Phenylacetate-CoA oxygenase
NYE86_19855	COG3396	Phenylacetate-CoA oxygenase
NYE86_19870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NYE86_19875	COG3345	alpha-galactosidase
NYE86_19885	COG3511	phospholipase C
NYE86_19900	COG1136	(ABC) transporter
NYE86_19900	COG4591	ABC-type transport system involved in lipoprotein release permease component
NYE86_19930	COG0559	Belongs to the binding-protein-dependent transport system permease family
NYE86_19975	COG0702	epimerase
NYE86_19995	COG1940	carbohydrate kinase activity
NYE86_20010	COG4213	ABC transporter substrate-binding protein
NYE86_20015	COG1172	Belongs to the binding-protein-dependent transport system permease family
NYE86_20020	COG1129	ABC transporter
NYE86_20035	COG2267	carboxylic ester hydrolase activity
NYE86_20060	COG0477	Major facilitator Superfamily
NYE86_20080	COG0583	DNA-binding transcription factor activity
NYE86_20120	COG3401	FG-GAP repeat protein
NYE86_20140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NYE86_20145	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NYE86_20155	COG0667	Aldo Keto reductase
NYE86_20165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NYE86_20225	COG3250	beta-galactosidase activity
NYE86_20335	COG2186	Transcriptional regulator
NYE86_20480	COG0667	Aldo Keto reductase
NYE86_20540	COG1175	transmembrane transport
NYE86_20545	COG0395	ABC-type sugar transport system, permease component
NYE86_20570	COG2267	carboxylic ester hydrolase activity
NYE86_20580	COG1470	cell adhesion involved in biofilm formation
NYE86_20580	COG0366	Alpha amylase catalytic
NYE86_20585	COG3345	alpha-galactosidase
NYE86_20600	COG1175	transmembrane transport
NYE86_20645	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NYE86_20650	COG1595	DNA-templated transcription, initiation
NYE86_20680	COG1140	nitrate reductase beta subunit
NYE86_20685	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NYE86_20725	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NYE86_20750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NYE86_20760	COG4608	Belongs to the ABC transporter superfamily
NYE86_20795	COG1131	(ABC) transporter
NYE86_20820	COG1301	dicarboxylic acid transport
NYE86_20835	COG3345	alpha-galactosidase
NYE86_20840	COG1940	carbohydrate kinase activity
NYE86_20840	COG1846	Transcriptional regulator
NYE86_20900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYE86_20920	COG1216	Glycosyl transferase, family 2
NYE86_20925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYE86_20950	COG1132	(ABC) transporter
NYE86_20970	COG1175	transmembrane transport
NYE86_20975	COG0395	ABC-type sugar transport system, permease component
NYE86_20980	COG0366	Alpha amylase catalytic
NYE86_21025	COG2815	serine threonine protein kinase
NYE86_21025	COG0515	serine threonine protein kinase
NYE86_21045	COG1595	DNA-templated transcription, initiation
NYE86_21055	COG1595	DNA-templated transcription, initiation
NYE86_21080	COG3507	Belongs to the glycosyl hydrolase 43 family
NYE86_21095	COG1082	Xylose isomerase domain protein TIM barrel
NYE86_21130	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_21135	COG1024	Enoyl-CoA hydratase
NYE86_21205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NYE86_21225	COG1051	belongs to the nudix hydrolase family
NYE86_21245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYE86_21275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NYE86_21285	COG1175	transmembrane transport
NYE86_21290	COG0395	ABC-type sugar transport system, permease component
NYE86_21315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NYE86_21345	COG2205	protein histidine kinase activity
NYE86_21350	COG0745	RESPONSE REGULATOR receiver
NYE86_21370	COG1063	alcohol dehydrogenase
NYE86_21425	COG2770	Histidine kinase
NYE86_21425	COG2208	phosphoserine phosphatase activity
NYE86_21465	COG1126	abc transporter atp-binding protein
NYE86_21485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_21490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_21515	COG2132	Multicopper oxidase
NYE86_21545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_21555	COG1404	Belongs to the peptidase S8 family
NYE86_21585	COG0405	Gamma-glutamyltransferase
NYE86_21605	COG2315	Protein conserved in bacteria
NYE86_21625	COG3104	oligopeptide transport
NYE86_21645	COG0488	(ABC) transporter
NYE86_21660	COG4134	Bacterial extracellular solute-binding protein
NYE86_21665	COG3842	ATPase activity
NYE86_21670	COG1175	transmembrane transport
NYE86_21675	COG4149	molybdate abc transporter
NYE86_21685	COG0640	Transcriptional regulator
NYE86_21695	COG0789	Transcriptional regulator
NYE86_21725	COG0596	Alpha beta hydrolase
NYE86_21730	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_21745	COG3261	NADH dehydrogenase
NYE86_21745	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NYE86_21750	COG0651	ATP synthesis coupled electron transport
NYE86_21760	COG0650	Formate hydrogenlyase subunit 4
NYE86_21770	COG3260	NADH ubiquinone oxidoreductase 20
NYE86_21790	COG1959	2 iron, 2 sulfur cluster binding
NYE86_21810	COG2124	cytochrome p450
NYE86_21820	COG2124	cytochrome p450
NYE86_21825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYE86_21840	COG0740	serine-type endopeptidase activity
NYE86_21845	COG0740	serine-type endopeptidase activity
NYE86_21870	COG1609	Transcriptional regulator
NYE86_21890	COG4821	SIS domain
NYE86_21905	COG3458	cephalosporin-C deacetylase activity
NYE86_21950	COG4948	Mandelate Racemase Muconate Lactonizing
NYE86_21965	COG1175	transmembrane transport
NYE86_22035	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NYE86_22045	COG0745	RESPONSE REGULATOR receiver
NYE86_22050	COG2205	protein histidine kinase activity
NYE86_22055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NYE86_22105	COG4209	transmembrane transport
NYE86_22110	COG0395	ABC-type sugar transport system, permease component
NYE86_22120	COG1609	Transcriptional regulator
NYE86_22130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NYE86_22220	COG2409	Drug exporters of the RND superfamily
NYE86_22260	COG0443	Heat shock 70 kDa protein
NYE86_22300	COG3387	PFAM Glycoside hydrolase 15-related
NYE86_22315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NYE86_22325	COG1294	oxidase, subunit
NYE86_22330	COG1271	oxidase subunit
NYE86_22340	COG1136	(ABC) transporter
NYE86_22355	COG3511	phospholipase C
NYE86_22365	COG0598	Magnesium transport protein CorA
NYE86_22385	COG1902	pentaerythritol trinitrate reductase activity
NYE86_22400	COG0640	Transcriptional regulator
NYE86_22405	COG3794	PFAM blue (type 1) copper domain protein
NYE86_22420	COG1116	anion transmembrane transporter activity
NYE86_22425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NYE86_22435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_22450	COG3537	Alpha-1,2-mannosidase
NYE86_22490	COG0534	Mate efflux family protein
NYE86_22495	COG0590	tRNA wobble adenosine to inosine editing
NYE86_22570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NYE86_22595	COG1136	(ABC) transporter
NYE86_22640	COG1737	Transcriptional regulator
NYE86_22665	COG2160	L-arabinose isomerase activity
NYE86_22680	COG1609	Transcriptional regulator
NYE86_22690	COG3507	Belongs to the glycosyl hydrolase 43 family
NYE86_22700	COG1609	Transcriptional regulator
NYE86_22720	COG1175	transmembrane transport
NYE86_22725	COG0395	ABC-type sugar transport system, permease component
NYE86_22750	COG1609	Transcriptional regulator
NYE86_22760	COG1175	transmembrane transport
NYE86_22790	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NYE86_22795	COG1691	(AIR) carboxylase
NYE86_22800	COG3875	lactate racemase activity
NYE86_22805	COG2186	Transcriptional regulator
NYE86_22810	COG4948	Mandelate Racemase Muconate Lactonizing
NYE86_22815	COG1879	ABC-type sugar transport system periplasmic component
NYE86_22825	COG4214	carbohydrate transport
NYE86_22860	COG3345	alpha-galactosidase
NYE86_22880	COG1175	transmembrane transport
NYE86_22885	COG0395	ABC-type sugar transport system, permease component
NYE86_22895	COG0667	Aldo Keto reductase
NYE86_22910	COG1063	alcohol dehydrogenase
NYE86_22915	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_22940	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_22945	COG1172	Belongs to the binding-protein-dependent transport system permease family
NYE86_22950	COG1172	Belongs to the binding-protein-dependent transport system permease family
NYE86_22960	COG1879	ABC-type sugar transport system periplasmic component
NYE86_22995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NYE86_23000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYE86_23005	COG0736	holo-[acyl-carrier-protein] synthase activity
NYE86_23010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYE86_23015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYE86_23020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NYE86_23025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NYE86_23050	COG0367	asparagine synthase
NYE86_23055	COG2304	oxidoreductase activity
NYE86_23080	COG3629	intracellular signal transduction
NYE86_23080	COG3903	Transcriptional regulator
NYE86_23085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NYE86_23090	COG2226	methyltransferase
NYE86_23095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NYE86_23100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NYE86_23105	COG2986	histidine ammonia-lyase
NYE86_23110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NYE86_23150	COG3237	CsbD-like
NYE86_23180	COG1733	regulation of RNA biosynthetic process
NYE86_23215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NYE86_23230	COG1940	carbohydrate kinase activity
NYE86_23245	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_23250	COG0492	ferredoxin-NADP+ reductase activity
NYE86_23285	COG1228	amidohydrolase
NYE86_23305	COG0515	serine threonine protein kinase
NYE86_23340	COG2197	response regulator
NYE86_23350	COG3220	belongs to the UPF0276 family
NYE86_23370	COG0613	PHP domain protein
NYE86_23385	COG2890	protein-(glutamine-N5) methyltransferase activity
NYE86_23415	COG2815	serine threonine protein kinase
NYE86_23415	COG0515	serine threonine protein kinase
NYE86_23420	COG3507	Belongs to the glycosyl hydrolase 43 family
NYE86_23420	COG2382	esterase
NYE86_23420	COG3693	PFAM glycoside hydrolase, family 10
NYE86_23440	COG2226	methyltransferase
NYE86_23445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NYE86_23470	COG1404	Belongs to the peptidase S8 family
NYE86_23485	COG0583	DNA-binding transcription factor activity
NYE86_23500	COG4941	Belongs to the sigma-70 factor family
NYE86_23560	COG2188	Transcriptional regulator
NYE86_23580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NYE86_23585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NYE86_23630	COG2755	lipolytic protein G-D-S-L family
NYE86_23650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NYE86_23665	COG1657	PFAM Prenyltransferase squalene oxidase
NYE86_23675	COG1233	COG1233 Phytoene dehydrogenase and related
NYE86_23685	COG1562	ergosterol biosynthetic process
NYE86_23690	COG1134	teichoic acid transport
NYE86_23710	COG0371	Dehydrogenase
NYE86_23730	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NYE86_23765	COG0488	(ABC) transporter
NYE86_23780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NYE86_23845	COG2313	pseudouridylate synthase activity
NYE86_23865	COG0287	Prephenate dehydrogenase
NYE86_23865	COG1605	Chorismate mutase
NYE86_23870	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NYE86_23875	COG0583	DNA-binding transcription factor activity
NYE86_23915	COG1309	transcriptional regulator
NYE86_23990	COG4266	Belongs to the allantoicase family
NYE86_24010	COG0138	bifunctional purine biosynthesis protein purh
NYE86_24015	COG1024	Enoyl-CoA hydratase
NYE86_24115	COG0745	RESPONSE REGULATOR receiver
NYE86_24120	COG2205	protein histidine kinase activity
NYE86_24130	COG1619	proteins homologs of microcin C7 resistance protein MccF
NYE86_24140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NYE86_24145	COG2362	D-Aminopeptidase
NYE86_24150	COG2226	methyltransferase
NYE86_24155	COG2208	phosphoserine phosphatase activity
NYE86_24155	COG1366	Belongs to the anti-sigma-factor antagonist family
NYE86_24155	COG2172	sigma factor antagonist activity
NYE86_24185	COG1250	3-hydroxyacyl-CoA dehydrogenase
NYE86_24200	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NYE86_24200	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NYE86_24210	COG1960	acyl-CoA dehydrogenase activity
NYE86_24215	COG0688	phosphatidylethanolamine metabolic process
NYE86_24225	COG1929	Belongs to the glycerate kinase type-1 family
NYE86_24255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NYE86_24260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NYE86_24295	COG1335	isochorismatase
NYE86_24315	COG3959	Transketolase, thiamine diphosphate binding domain
NYE86_24320	COG0765	amino acid transport
NYE86_24325	COG0765	amino acid transport
NYE86_24330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NYE86_24335	COG1126	abc transporter atp-binding protein
NYE86_24360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NYE86_24370	COG1940	carbohydrate kinase activity
NYE86_24375	COG1129	ABC transporter
NYE86_24390	COG2188	Transcriptional regulator
NYE86_24395	COG0673	inositol 2-dehydrogenase activity
NYE86_24410	COG3718	enzyme involved in inositol metabolism
NYE86_24415	COG3962	Belongs to the TPP enzyme family
NYE86_24460	COG3655	Transcriptional regulator
NYE86_24470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NYE86_24485	COG1940	carbohydrate kinase activity
NYE86_24495	COG1175	transmembrane transport
NYE86_24500	COG0395	ABC-type sugar transport system, permease component
NYE86_24505	COG2723	6-phospho-beta-galactosidase activity
NYE86_24510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NYE86_24515	COG1414	Transcriptional regulator
NYE86_24540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NYE86_24555	COG2351	hydroxyisourate hydrolase activity
NYE86_24600	COG1131	(ABC) transporter
NYE86_24635	COG3622	Belongs to the hyi family
NYE86_24640	COG2084	Dehydrogenase
NYE86_24650	COG3960	tartronate-semialdehyde synthase activity
NYE86_24655	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_24660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NYE86_24670	COG1280	lysine exporter protein (LysE YggA)
NYE86_24695	COG2188	Transcriptional regulator
NYE86_24700	COG2182	Extracellular solute-binding protein
NYE86_24705	COG1175	transmembrane transport
NYE86_24710	COG0395	ABC-type sugar transport system, permease component
NYE86_24755	COG2252	PERMEase
NYE86_24760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NYE86_24775	COG2508	Transcriptional regulator
NYE86_24775	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NYE86_24810	COG0028	Belongs to the TPP enzyme family
NYE86_24840	COG1131	(ABC) transporter
NYE86_24850	COG4585	Histidine kinase
NYE86_24855	COG2197	response regulator
NYE86_24865	COG1162	GTPase activity
NYE86_24890	COG0477	Major facilitator Superfamily
NYE86_24900	COG2226	methyltransferase
NYE86_24920	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_24925	COG0725	ABC transporter, periplasmic molybdate-binding protein
NYE86_24970	COG1960	acyl-CoA dehydrogenase activity
NYE86_24980	COG1846	Transcriptional regulator
NYE86_24980	COG0456	acetyltransferase
NYE86_24995	COG0175	sulfate reduction
NYE86_25000	COG0529	Catalyzes the synthesis of activated sulfate
NYE86_25025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NYE86_25085	COG4221	oxidoreductase activity
NYE86_25100	COG0583	DNA-binding transcription factor activity
NYE86_25105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NYE86_25120	COG2326	polyphosphate kinase activity
NYE86_25140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NYE86_25145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NYE86_25165	COG1063	alcohol dehydrogenase
NYE86_25170	COG1733	regulation of RNA biosynthetic process
NYE86_25175	COG3253	May function as heme-dependent peroxidase
NYE86_25180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NYE86_25195	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NYE86_25215	COG0183	Belongs to the thiolase family
NYE86_25220	COG1024	Enoyl-CoA hydratase
NYE86_25220	COG1250	3-hydroxyacyl-CoA dehydrogenase
NYE86_25240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NYE86_25245	COG4214	carbohydrate transport
NYE86_25255	COG4213	ABC transporter substrate-binding protein
NYE86_25260	COG1940	carbohydrate kinase activity
NYE86_25265	COG0395	ABC-type sugar transport system, permease component
NYE86_25270	COG1175	transmembrane transport
NYE86_25275	COG1653	transport
NYE86_25280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NYE86_25295	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NYE86_25305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NYE86_25315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NYE86_25320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NYE86_25325	COG2235	arginine
NYE86_25330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NYE86_25375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NYE86_25385	COG2376	Dihydroxyacetone kinase
NYE86_25390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NYE86_25395	COG0531	amino acid
NYE86_25400	COG0569	domain protein
NYE86_25430	COG4591	ABC-type transport system involved in lipoprotein release permease component
NYE86_25430	COG1136	(ABC) transporter
NYE86_25435	COG1136	(ABC) transporter
NYE86_25435	COG0577	efflux transmembrane transporter activity
NYE86_25455	COG0756	dUTP diphosphatase activity
NYE86_25480	COG2205	protein histidine kinase activity
NYE86_25485	COG0745	RESPONSE REGULATOR receiver
NYE86_25495	COG0483	inositol monophosphate 1-phosphatase activity
NYE86_25500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NYE86_25535	COG0673	inositol 2-dehydrogenase activity
NYE86_25545	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_25575	COG4948	Mandelate Racemase Muconate Lactonizing
NYE86_25580	COG1414	Transcriptional regulator
NYE86_25590	COG1175	transmembrane transport
NYE86_25595	COG0395	ABC-type sugar transport system, permease component
NYE86_25600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NYE86_25615	COG1435	thymidine kinase activity
NYE86_25635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NYE86_25640	COG1802	Transcriptional regulator
NYE86_25650	COG0612	Peptidase, M16
NYE86_25655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NYE86_25670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NYE86_25680	COG3290	protein histidine kinase activity
NYE86_25685	COG4565	transcriptional regulatory protein
NYE86_25690	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NYE86_25700	COG2197	response regulator
NYE86_25705	COG4585	Histidine kinase
NYE86_25720	COG0714	Associated with various cellular activities
NYE86_25725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NYE86_25730	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NYE86_25735	COG4715	Zinc finger, swim domain protein
NYE86_25740	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_25745	COG2045	Belongs to the ComB family
NYE86_25795	COG0187	DNA topoisomerase II activity
NYE86_25810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NYE86_25815	COG2186	Transcriptional regulator
NYE86_25820	COG3842	ATPase activity
NYE86_25875	COG1222	aaa ATPase
NYE86_25945	COG0514	ATP-dependent DNA helicase (RecQ)
NYE86_25960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NYE86_25970	COG0588	phosphoglycerate mutase activity
NYE86_25975	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_25990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NYE86_25995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NYE86_26000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NYE86_26050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NYE86_26055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NYE86_26060	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NYE86_26070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NYE86_26085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NYE86_26095	COG2205	protein histidine kinase activity
NYE86_26100	COG0745	RESPONSE REGULATOR receiver
NYE86_26115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NYE86_26145	COG1201	RNA secondary structure unwinding
NYE86_26150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NYE86_26160	COG0783	Belongs to the Dps family
NYE86_26165	COG1396	sequence-specific DNA binding
NYE86_26170	COG1058	Belongs to the CinA family
NYE86_26170	COG1546	Belongs to the CinA family
NYE86_26180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NYE86_26190	COG1674	ftsk spoiiie
NYE86_26200	COG0784	Response regulator, receiver
NYE86_26200	COG2205	protein histidine kinase activity
NYE86_26205	COG2208	phosphoserine phosphatase activity
NYE86_26205	COG2770	Histidine kinase
NYE86_26215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NYE86_26235	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NYE86_26240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NYE86_26245	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NYE86_26260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NYE86_26265	COG0612	Peptidase, M16
NYE86_26270	COG1185	polyribonucleotide nucleotidyltransferase activity
NYE86_26275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NYE86_26285	COG1674	ftsk spoiiie
NYE86_26325	COG1404	Belongs to the peptidase S8 family
NYE86_26375	COG1131	(ABC) transporter
NYE86_26385	COG4585	Histidine kinase
NYE86_26390	COG2197	response regulator
NYE86_26405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NYE86_26410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NYE86_26435	COG0779	Required for maturation of 30S ribosomal subunits
NYE86_26455	COG0456	acetyltransferase
NYE86_26465	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NYE86_26470	COG0750	zinc metalloprotease
NYE86_26475	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NYE86_26495	COG2508	Transcriptional regulator
NYE86_26525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NYE86_26530	COG1177	transmembrane transport
NYE86_26535	COG1176	ABC-type spermidine putrescine transport system, permease component I
NYE86_26540	COG3842	ATPase activity
NYE86_26550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NYE86_26560	COG1012	belongs to the aldehyde dehydrogenase family
NYE86_26570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NYE86_26595	COG3842	ATPase activity
NYE86_26600	COG4149	molybdate abc transporter
NYE86_26610	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NYE86_26615	COG0575	Belongs to the CDS family
NYE86_26620	COG0233	cytoplasmic translational termination
NYE86_26625	COG0528	UMP kinase activity
NYE86_26630	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NYE86_26635	COG0052	Belongs to the universal ribosomal protein uS2 family
NYE86_26650	COG1191	sigma factor activity
NYE86_26665	COG4974	Belongs to the 'phage' integrase family
NYE86_26760	COG0210	DNA helicase
NYE86_26785	COG2826	transposase and inactivated derivatives, IS30 family
NYE86_26805	COG0792	nuclease activity
NYE86_26815	COG0681	Belongs to the peptidase S26 family
NYE86_26820	COG0681	Belongs to the peptidase S26 family
NYE86_26825	COG0681	Belongs to the peptidase S26 family
NYE86_26835	COG0335	large ribosomal subunit rRNA binding
NYE86_26840	COG0336	Belongs to the RNA methyltransferase TrmD family
NYE86_26845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NYE86_26850	COG1837	Belongs to the UPF0109 family
NYE86_26855	COG0228	four-way junction DNA binding
NYE86_26865	COG0442	prolyl-tRNA aminoacylation
NYE86_26890	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NYE86_26920	COG0477	Major facilitator Superfamily
NYE86_26935	COG1254	Belongs to the acylphosphatase family
NYE86_26940	COG2340	Cysteine-rich secretory protein family
NYE86_26945	COG1733	regulation of RNA biosynthetic process
NYE86_26950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NYE86_26955	COG0571	ribonuclease III activity
NYE86_26960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NYE86_26975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NYE86_26980	COG0742	ribosomal rna small subunit methyltransferase
NYE86_26995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NYE86_27000	COG1461	Dihydroxyacetone kinase
NYE86_27005	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NYE86_27010	COG0351	phosphomethylpyrimidine kinase
NYE86_27030	COG1181	Belongs to the D-alanine--D-alanine ligase family
NYE86_27035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NYE86_27045	COG1920	GTP binding
NYE86_27055	COG0776	regulation of translation
NYE86_27065	COG0066	3-isopropylmalate dehydratase activity
NYE86_27070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NYE86_27075	COG1414	Transcriptional regulator
NYE86_27095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NYE86_27100	COG0179	Fumarylacetoacetate (FAA) hydrolase
NYE86_27115	COG2018	Roadblock/LC7 domain
NYE86_27135	COG2018	Roadblock/LC7 domain
NYE86_27155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NYE86_27165	COG2301	Belongs to the HpcH HpaI aldolase family
NYE86_27205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NYE86_27210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NYE86_27215	COG0473	3-isopropylmalate dehydrogenase activity
NYE86_27220	COG1012	belongs to the aldehyde dehydrogenase family
NYE86_27225	COG0506	proline dehydrogenase activity
NYE86_27235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NYE86_27240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NYE86_27245	COG0440	acetolactate synthase activity
NYE86_27265	COG0667	Aldo Keto reductase
NYE86_27270	COG2133	pyrroloquinoline quinone binding
NYE86_27275	COG2197	response regulator
NYE86_27295	COG2409	Drug exporters of the RND superfamily
NYE86_27300	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NYE86_27310	COG0154	amidase activity
NYE86_27315	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NYE86_27325	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NYE86_27340	COG1611	Belongs to the LOG family
NYE86_27345	COG0482	sulfurtransferase activity
NYE86_27375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NYE86_27380	COG0509	glycine decarboxylation via glycine cleavage system
NYE86_27385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NYE86_27390	COG1760	l-serine dehydratase
NYE86_27415	COG1595	DNA-templated transcription, initiation
NYE86_27490	COG2267	carboxylic ester hydrolase activity
NYE86_27530	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_27535	COG1132	(ABC) transporter
NYE86_27540	COG1132	(ABC) transporter
NYE86_27555	COG1278	Cold shock
NYE86_27560	COG0513	Belongs to the DEAD box helicase family
NYE86_27565	COG0058	SHG alpha-glucan phosphorylase activity
NYE86_27570	COG0366	Alpha amylase catalytic
NYE86_27575	COG0366	Alpha amylase catalytic
NYE86_27580	COG3281	Trehalose synthase
NYE86_27585	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NYE86_27590	COG0205	6-phosphofructokinase activity
NYE86_27595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NYE86_27600	COG0280	phosphate acetyltransferase
NYE86_27600	COG0857	belongs to the CobB CobQ family
NYE86_27605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NYE86_27645	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NYE86_27645	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NYE86_27670	COG1595	DNA-templated transcription, initiation
NYE86_27730	COG1695	Transcriptional regulator
NYE86_27750	COG2318	DinB family
NYE86_27760	COG0183	Belongs to the thiolase family
NYE86_27805	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NYE86_27825	COG1250	3-hydroxyacyl-CoA dehydrogenase
NYE86_27840	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NYE86_27845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NYE86_27850	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NYE86_27855	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NYE86_27860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NYE86_27865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NYE86_27870	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NYE86_27885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NYE86_27900	COG2890	protein-(glutamine-N5) methyltransferase activity
NYE86_27905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NYE86_27910	COG0254	rRNA binding
NYE86_27930	COG0083	homoserine kinase activity
NYE86_27935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NYE86_27945	COG0019	diaminopimelate decarboxylase activity
NYE86_27950	COG0018	arginyl-trna synthetase
NYE86_28075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NYE86_28080	COG1733	regulation of RNA biosynthetic process
NYE86_28085	COG0477	Major facilitator Superfamily
NYE86_28095	COG3537	Alpha-1,2-mannosidase
NYE86_28120	COG3424	synthase
NYE86_28125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NYE86_28130	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NYE86_28185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NYE86_28190	COG3629	intracellular signal transduction
NYE86_28190	COG3903	Transcriptional regulator
NYE86_28200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NYE86_28215	COG0463	Glycosyl transferase, family 2
NYE86_28275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NYE86_28275	COG4124	Belongs to the glycosyl hydrolase 26 family
NYE86_28295	COG1172	Belongs to the binding-protein-dependent transport system permease family
NYE86_28300	COG1129	ABC transporter
NYE86_28340	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NYE86_28370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NYE86_28385	COG2160	L-arabinose isomerase activity
NYE86_28400	COG1609	Transcriptional regulator
NYE86_28425	COG0559	Belongs to the binding-protein-dependent transport system permease family
NYE86_28430	COG1172	Belongs to the binding-protein-dependent transport system permease family
NYE86_28440	COG3629	intracellular signal transduction
NYE86_28440	COG3903	Transcriptional regulator
NYE86_28505	COG1309	transcriptional regulator
NYE86_28575	COG2318	DinB family
NYE86_28580	COG1733	regulation of RNA biosynthetic process
NYE86_28590	COG0673	inositol 2-dehydrogenase activity
NYE86_28610	COG0386	Belongs to the glutathione peroxidase family
NYE86_28625	COG0768	penicillin binding
NYE86_28635	COG2843	Capsule synthesis protein
NYE86_28725	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NYE86_28740	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NYE86_28745	COG0745	RESPONSE REGULATOR receiver
NYE86_28750	COG2205	protein histidine kinase activity
NYE86_28790	COG2255	four-way junction helicase activity
NYE86_28815	COG0604	alcohol dehydrogenase
NYE86_28825	COG0681	Belongs to the peptidase S26 family
NYE86_28835	COG1126	abc transporter atp-binding protein
NYE86_28840	COG0765	amino acid transport
NYE86_28850	COG0281	malic enzyme
NYE86_28855	COG3118	belongs to the thioredoxin family
NYE86_28855	COG0492	ferredoxin-NADP+ reductase activity
NYE86_28860	COG0789	Transcriptional regulator
NYE86_28880	COG1737	Transcriptional regulator
NYE86_28885	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NYE86_28905	COG1597	lipid kinase activity
NYE86_28930	COG0363	glucosamine-6-phosphate deaminase activity
NYE86_28945	COG2188	Transcriptional regulator
NYE86_28950	COG2182	Extracellular solute-binding protein
NYE86_28955	COG1175	transmembrane transport
NYE86_28960	COG0395	ABC-type sugar transport system, permease component
NYE86_28965	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_28990	COG0242	peptide deformylase activity
NYE86_29005	COG5662	AntiSigma factor
NYE86_29010	COG1595	DNA-templated transcription, initiation
NYE86_29020	COG2135	peptidase activity
NYE86_29030	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NYE86_29035	COG1162	GTPase activity
NYE86_29040	COG2076	Multidrug Resistance protein
NYE86_29050	COG0483	inositol monophosphate 1-phosphatase activity
NYE86_29060	COG0753	catalase activity
NYE86_29095	COG1615	UPF0182 protein
NYE86_29195	COG0210	DNA helicase
NYE86_29205	COG0210	DNA helicase
NYE86_29300	COG0513	Belongs to the DEAD box helicase family
NYE86_29315	COG2095	MarC family integral membrane protein
NYE86_29330	COG2814	Major facilitator Superfamily
NYE86_29340	COG0598	Magnesium transport protein CorA
NYE86_29380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NYE86_29390	COG1595	DNA-templated transcription, initiation
NYE86_29405	COG1024	Enoyl-CoA hydratase
NYE86_29410	COG0519	Catalyzes the synthesis of GMP from XMP
NYE86_29420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NYE86_29425	COG1611	Belongs to the LOG family
NYE86_29435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NYE86_29460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NYE86_29460	COG0456	acetyltransferase
NYE86_29465	COG2912	Transglutaminase-like superfamily
NYE86_29485	COG2197	response regulator
NYE86_29505	COG1131	(ABC) transporter
NYE86_29515	COG4585	Histidine kinase
NYE86_29530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NYE86_29545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NYE86_29550	COG4166	transmembrane transport
NYE86_29555	COG0601	transmembrane transport
NYE86_29560	COG0444	Belongs to the ABC transporter superfamily
NYE86_29565	COG4608	Belongs to the ABC transporter superfamily
NYE86_29570	COG4608	Belongs to the ABC transporter superfamily
NYE86_29575	COG0444	Belongs to the ABC transporter superfamily
NYE86_29580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NYE86_29585	COG0601	transmembrane transport
NYE86_29595	COG4608	Belongs to the ABC transporter superfamily
NYE86_29605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NYE86_29610	COG0601	transmembrane transport
NYE86_29615	COG4166	transmembrane transport
NYE86_29620	COG1217	gtp-binding protein TYPA
NYE86_29645	COG1053	succinate dehydrogenase
NYE86_29665	COG1842	Phage shock protein A
NYE86_29690	COG0698	ribose 5-phosphate isomerase
NYE86_29715	COG0583	DNA-binding transcription factor activity
NYE86_29745	COG3629	intracellular signal transduction
NYE86_29745	COG3903	Transcriptional regulator
NYE86_29780	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NYE86_29795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NYE86_29855	COG0012	GTP binding
NYE86_29865	COG1940	carbohydrate kinase activity
NYE86_29870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NYE86_29880	COG1570	exodeoxyribonuclease VII activity
NYE86_29885	COG1722	exodeoxyribonuclease VII activity
NYE86_29890	COG0778	Nitroreductase
NYE86_29915	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NYE86_29915	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NYE86_29925	COG0596	Alpha beta hydrolase
NYE86_29935	COG0114	fumarate hydratase activity
NYE86_29945	COG2226	methyltransferase
NYE86_29970	COG1136	(ABC) transporter
NYE86_29990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NYE86_29995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NYE86_30000	COG0667	Aldo Keto reductase
NYE86_30055	COG2894	cell division
NYE86_30080	COG1414	Transcriptional regulator
NYE86_30095	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NYE86_30110	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NYE86_30120	COG0477	Major facilitator Superfamily
NYE86_30130	COG1331	Highly conserved protein containing a thioredoxin domain
NYE86_30170	COG0367	asparagine synthase
NYE86_30190	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
NYE86_30205	COG1136	(ABC) transporter
NYE86_30225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NYE86_30235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NYE86_30250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NYE86_30290	COG1070	Carbohydrate kinase
NYE86_30295	COG1940	carbohydrate kinase activity
NYE86_30310	COG2986	histidine ammonia-lyase
NYE86_30320	COG1024	Enoyl-CoA hydratase
NYE86_30340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NYE86_30370	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NYE86_30380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NYE86_30395	COG0424	maF-like protein
NYE86_30405	COG4770	biotin carboxylase activity
NYE86_30420	COG1349	DNA-binding transcription factor activity
NYE86_30445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NYE86_30475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NYE86_30505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NYE86_30535	COG1012	belongs to the aldehyde dehydrogenase family
NYE86_30540	COG1012	belongs to the aldehyde dehydrogenase family
NYE86_30545	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NYE86_30565	COG1595	DNA-templated transcription, initiation
NYE86_30570	COG0745	RESPONSE REGULATOR receiver
NYE86_30575	COG2205	protein histidine kinase activity
NYE86_30595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NYE86_30615	COG1079	Belongs to the binding-protein-dependent transport system permease family
NYE86_30620	COG4603	Belongs to the binding-protein-dependent transport system permease family
NYE86_30625	COG3845	ABC transporter
NYE86_30630	COG1744	ABC transporter substrate-binding protein PnrA-like
NYE86_30635	COG1473	amidohydrolase
NYE86_30635	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NYE86_30650	COG2089	acid synthase
NYE86_30655	COG1083	cytidylyl-transferase
NYE86_30665	COG1216	Glycosyl transferase, family 2
NYE86_30675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NYE86_30675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NYE86_30705	COG2009	succinate dehydrogenase
NYE86_30715	COG1053	succinate dehydrogenase
NYE86_30750	COG2205	protein histidine kinase activity
NYE86_30755	COG0745	RESPONSE REGULATOR receiver
NYE86_30760	COG2409	Drug exporters of the RND superfamily
NYE86_30775	COG1309	transcriptional regulator
NYE86_30785	COG1686	Belongs to the peptidase S11 family
NYE86_30800	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NYE86_30825	COG0180	Tryptophanyl-tRNA synthetase
NYE86_30830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NYE86_30840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NYE86_30845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYE86_30850	COG0039	L-malate dehydrogenase activity
NYE86_30865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NYE86_30880	COG0138	bifunctional purine biosynthesis protein purh
NYE86_30910	COG0045	succinate-CoA ligase (ADP-forming) activity
NYE86_30915	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NYE86_30925	COG0714	Associated with various cellular activities
NYE86_30960	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NYE86_30960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NYE86_30970	COG0739	heme binding
NYE86_31020	COG2197	response regulator
NYE86_31040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NYE86_31040	COG0519	Catalyzes the synthesis of GMP from XMP
NYE86_31050	COG1012	belongs to the aldehyde dehydrogenase family
NYE86_31055	COG0515	serine threonine protein kinase
NYE86_31055	COG2815	serine threonine protein kinase
NYE86_31060	COG0515	serine threonine protein kinase
NYE86_31070	COG2815	serine threonine protein kinase
NYE86_31070	COG0515	serine threonine protein kinase
NYE86_31075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NYE86_31090	COG0516	GMP reductase activity
NYE86_31100	COG1595	DNA-templated transcription, initiation
NYE86_31150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NYE86_31160	COG0726	polysaccharide deacetylase
NYE86_31170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NYE86_31195	COG0802	atpase or kinase
NYE86_31205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NYE86_31225	COG0736	holo-[acyl-carrier-protein] synthase activity
NYE86_31230	COG1072	(Pantothenic acid kinase))
NYE86_31235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NYE86_31240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NYE86_31245	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NYE86_31250	COG0488	(ABC) transporter
NYE86_31265	COG0101	tRNA pseudouridine synthase activity
NYE86_31270	COG0203	ribosomal protein L17
NYE86_31280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NYE86_31285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NYE86_31290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NYE86_31295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NYE86_31300	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NYE86_31310	COG0563	adenylate kinase activity
NYE86_31320	COG0200	Binds to the 23S rRNA
NYE86_31325	COG1841	ribosomal large subunit assembly
NYE86_31330	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NYE86_31335	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NYE86_31340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NYE86_31345	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NYE86_31350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NYE86_31355	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NYE86_31360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NYE86_31365	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NYE86_31370	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NYE86_31375	COG0255	Belongs to the universal ribosomal protein uL29 family
NYE86_31380	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NYE86_31385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NYE86_31390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NYE86_31395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NYE86_31400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NYE86_31405	COG0089	rRNA binding
NYE86_31410	COG0088	Forms part of the polypeptide exit tunnel
NYE86_31415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NYE86_31420	COG0051	transcription antitermination factor activity, RNA binding
NYE86_31425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NYE86_31430	COG1051	belongs to the nudix hydrolase family
NYE86_31435	COG3896	Chloramphenicol phosphotransferase-like protein
NYE86_31515	COG1116	anion transmembrane transporter activity
NYE86_31540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NYE86_31545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NYE86_31550	COG0049	tRNA binding
NYE86_31555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NYE86_31565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NYE86_31570	COG0085	RNA polymerase activity
NYE86_31575	COG0222	ribosome binding
NYE86_31580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NYE86_31590	COG0081	regulation of translation
NYE86_31595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NYE86_31600	COG2755	lipolytic protein G-D-S-L family
NYE86_31620	COG0436	Aminotransferase
NYE86_31625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NYE86_31640	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NYE86_31645	COG0477	Major facilitator Superfamily
NYE86_31660	COG2030	dehydratase
NYE86_31665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NYE86_31685	COG0702	epimerase
NYE86_31710	COG1666	GTP binding
NYE86_31715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NYE86_31720	COG3304	Inner membrane component domain
NYE86_31725	COG0501	Belongs to the peptidase M48B family
NYE86_31730	COG1007	ATP synthesis coupled electron transport
NYE86_31745	COG0713	ATP synthesis coupled electron transport
NYE86_31750	COG0839	Belongs to the complex I subunit 6 family
NYE86_31755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NYE86_31760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NYE86_31770	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NYE86_31775	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NYE86_31785	COG4585	Histidine kinase
NYE86_31800	COG0674	pyruvate-flavodoxin oxidoreductase activity
NYE86_31800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NYE86_31805	COG1013	pyruvate-flavodoxin oxidoreductase activity
NYE86_31820	COG0702	epimerase
NYE86_31830	COG0655	NAD(P)H dehydrogenase (quinone) activity
NYE86_31855	COG0142	geranyltranstransferase activity
NYE86_31860	COG3572	ergothioneine biosynthetic process
NYE86_31865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NYE86_31875	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NYE86_31900	COG1007	ATP synthesis coupled electron transport
NYE86_31910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NYE86_31915	COG0713	ATP synthesis coupled electron transport
NYE86_31925	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NYE86_31930	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NYE86_31935	COG1034	ATP synthesis coupled electron transport
NYE86_31940	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NYE86_31950	COG0649	NAD binding
NYE86_31955	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NYE86_31960	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NYE86_31980	COG0438	transferase activity, transferring glycosyl groups
NYE86_31995	COG1215	transferase activity, transferring glycosyl groups
NYE86_32030	COG2226	methyltransferase
NYE86_32090	COG2226	methyltransferase
NYE86_32095	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NYE86_32100	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NYE86_32105	COG1278	Cold shock
NYE86_32115	COG0183	Belongs to the thiolase family
NYE86_32155	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NYE86_32160	COG1522	sequence-specific DNA binding
NYE86_32165	COG0163	prenyltransferase activity
NYE86_32180	COG0109	protoheme IX farnesyltransferase activity
NYE86_32185	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NYE86_32190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NYE86_32195	COG1333	cytochrome c biogenesis protein
NYE86_32200	COG0785	Cytochrome C biogenesis protein
NYE86_32205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NYE86_32215	COG0406	alpha-ribazole phosphatase activity
NYE86_32220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NYE86_32235	COG1181	Belongs to the D-alanine--D-alanine ligase family
NYE86_32250	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NYE86_32255	COG0583	DNA-binding transcription factor activity
NYE86_32270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NYE86_32275	COG3404	Formiminotransferase-cyclodeaminase
NYE86_32285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NYE86_32315	COG1690	Belongs to the RtcB family
NYE86_32340	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
NYE86_32345	COG0018	arginyl-trna synthetase
NYE86_32360	COG0113	porphobilinogen synthase activity
NYE86_32370	COG0181	hydroxymethylbilane synthase activity
NYE86_32375	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NYE86_32380	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NYE86_32440	COG0123	including yeast histone deacetylase and acetoin utilization protein
NYE86_32450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NYE86_32470	COG0180	Tryptophanyl-tRNA synthetase
NYE86_32475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NYE86_32485	COG0842	Transport permease protein
NYE86_32485	COG1129	ABC transporter
NYE86_32530	COG2755	lipolytic protein G-D-S-L family
NYE86_32535	COG0129	dihydroxy-acid dehydratase activity
NYE86_32550	COG1082	Xylose isomerase domain protein TIM barrel
NYE86_32555	COG0248	Ppx GppA phosphatase
NYE86_32590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NYE86_32600	COG1194	a g-specific adenine glycosylase
NYE86_32605	COG1595	DNA-templated transcription, initiation
NYE86_32615	COG0745	RESPONSE REGULATOR receiver
NYE86_32620	COG2205	protein histidine kinase activity
NYE86_32645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NYE86_32675	COG1196	nuclear chromosome segregation
NYE86_32675	COG0739	heme binding
NYE86_32675	COG0741	lytic transglycosylase activity
NYE86_32695	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NYE86_32715	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NYE86_32725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NYE86_32730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NYE86_32740	COG4585	Histidine kinase
NYE86_32745	COG2197	response regulator
NYE86_32755	COG0604	alcohol dehydrogenase
NYE86_32755	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_32755	COG3321	synthase
NYE86_32770	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NYE86_32790	COG2197	response regulator
NYE86_32805	COG0076	glutamate decarboxylase activity
NYE86_32815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NYE86_32815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NYE86_32860	COG2197	response regulator
NYE86_32875	COG0277	FAD linked oxidase domain protein
NYE86_32970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NYE86_32975	COG2188	Transcriptional regulator
NYE86_32995	COG0563	adenylate kinase activity
NYE86_33020	COG2197	response regulator
NYE86_33050	COG2197	response regulator
NYE86_33090	COG3842	ATPase activity
NYE86_33110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NYE86_33115	COG0215	cysteine-tRNA ligase activity
NYE86_33120	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NYE86_33125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NYE86_33130	COG1329	Transcriptional regulator
NYE86_33145	COG5002	protein histidine kinase activity
NYE86_33160	COG1131	(ABC) transporter
NYE86_33170	COG4585	Histidine kinase
NYE86_33175	COG2197	response regulator
NYE86_33235	COG2188	Transcriptional regulator
NYE86_33265	COG0588	phosphoglycerate mutase activity
NYE86_33285	COG0438	transferase activity, transferring glycosyl groups
NYE86_33315	COG3321	synthase
NYE86_33315	COG1028	Short-chain dehydrogenase reductase Sdr
NYE86_33315	COG0604	alcohol dehydrogenase
NYE86_33345	COG1090	epimerase
NYE86_33360	COG0583	DNA-binding transcription factor activity
NYE86_33425	COG4552	Acetyltransferase involved in intracellular survival and related
NYE86_33435	COG1490	D-aminoacyl-tRNA deacylase activity
NYE86_33440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NYE86_33450	COG3485	protocatechuate 3,4-dioxygenase
NYE86_33485	COG2897	thiosulfate sulfurtransferase activity
NYE86_33510	COG0745	RESPONSE REGULATOR receiver
NYE86_33515	COG1609	Transcriptional regulator
NYE86_33520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NYE86_33525	COG0745	RESPONSE REGULATOR receiver
NYE86_33535	COG2271	Major facilitator Superfamily
NYE86_33540	COG0456	acetyltransferase
NYE86_33555	COG0494	nUDIX hydrolase
NYE86_33555	COG0406	alpha-ribazole phosphatase activity
NYE86_33575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NYE86_33580	COG0306	phosphate transporter
NYE86_33590	COG1937	Protein conserved in bacteria
NYE86_33610	COG0277	FAD linked oxidase domain protein
NYE86_33620	COG0739	heme binding
NYE86_33620	COG0741	lytic transglycosylase activity
NYE86_33620	COG1196	nuclear chromosome segregation
NYE86_33665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NYE86_33670	COG4209	transmembrane transport
NYE86_33675	COG0395	ABC-type sugar transport system, permease component
NYE86_33685	COG1609	Transcriptional regulator
NYE86_33735	COG1252	NADH dehydrogenase
NYE86_33760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NYE86_33765	COG1754	DNA topoisomerase type I activity
NYE86_33765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NYE86_33790	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NYE86_33795	COG2172	sigma factor antagonist activity
NYE86_33800	COG1366	Belongs to the anti-sigma-factor antagonist family
NYE86_33805	COG1205	dead DEAH box helicase
NYE86_33805	COG1111	helicase
NYE86_33870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NYE86_33875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NYE86_33885	COG2267	carboxylic ester hydrolase activity
NYE86_33920	COG3844	kynureninase activity
NYE86_33925	COG3483	tryptophan 2,3-dioxygenase activity
NYE86_33945	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NYE86_33960	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NYE86_33970	COG0302	gtp cyclohydrolase
NYE86_34005	COG2175	clavaminate synthase activity
NYE86_34010	COG1609	Transcriptional regulator
NYE86_34015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NYE86_34030	COG3842	ATPase activity
NYE86_34035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NYE86_34040	COG2076	Multidrug Resistance protein
NYE86_34055	COG0137	argininosuccinate synthase activity
NYE86_34060	COG2409	Drug exporters of the RND superfamily
NYE86_34080	COG0542	response to heat
NYE86_34090	COG0789	Transcriptional regulator
NYE86_34095	COG0484	heat shock protein binding
NYE86_34100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NYE86_34105	COG0443	Heat shock 70 kDa protein
NYE86_34115	COG0247	lactate metabolic process
NYE86_34115	COG2181	nitrate reductase activity
NYE86_34130	COG0717	Belongs to the dCTP deaminase family
NYE86_34155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NYE86_34160	COG0640	Transcriptional regulator
NYE86_34265	COG0477	Major facilitator Superfamily
NYE86_34285	COG0667	Aldo Keto reductase
NYE86_34290	COG1522	sequence-specific DNA binding
NYE86_34315	COG1309	transcriptional regulator
NYE86_34320	COG3158	transport of potassium into the cell
NYE86_34330	COG1063	alcohol dehydrogenase
NYE86_34360	COG0789	Transcriptional regulator
NYE86_34420	COG0789	Transcriptional regulator
NYE86_34425	COG0667	Aldo Keto reductase
NYE86_34430	COG3511	phospholipase C
NYE86_34450	COG1131	(ABC) transporter
NYE86_34455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NYE86_34540	COG0596	Alpha beta hydrolase
NYE86_34560	COG1309	transcriptional regulator
NYE86_34590	COG4977	sequence-specific DNA binding
NYE86_34630	COG3250	beta-galactosidase activity
NYE86_34690	COG1595	DNA-templated transcription, initiation
NYE86_34715	COG1595	DNA-templated transcription, initiation
NYE86_34770	COG2837	iron assimilation
NYE86_34820	COG2205	protein histidine kinase activity
NYE86_34895	COG1720	tRNA m6t6A37 methyltransferase activity
NYE86_35015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NYE86_35020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NYE86_35035	COG1595	DNA-templated transcription, initiation
NYE86_35070	COG2084	Dehydrogenase
NYE86_35105	COG2197	response regulator
NYE86_35110	COG4585	Histidine kinase
NYE86_35135	COG0243	molybdopterin cofactor binding
NYE86_35175	COG0438	transferase activity, transferring glycosyl groups
NYE86_35180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NYE86_35200	COG0438	transferase activity, transferring glycosyl groups
NYE86_35225	COG2304	oxidoreductase activity
NYE86_35245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NYE86_35250	COG1993	acr, cog1993
NYE86_35255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NYE86_35280	COG0477	Major facilitator Superfamily
NYE86_35285	COG0583	DNA-binding transcription factor activity
NYE86_35305	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NYE86_35350	COG1191	sigma factor activity
NYE86_35355	COG1191	sigma factor activity
NYE86_35385	COG2205	protein histidine kinase activity
NYE86_35390	COG0745	RESPONSE REGULATOR receiver
NYE86_35485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NYE86_35495	COG0318	PFAM AMP-dependent synthetase and ligase
NYE86_35500	COG1595	DNA-templated transcription, initiation
NYE86_35520	COG1959	2 iron, 2 sulfur cluster binding
NYE86_35585	COG2188	Transcriptional regulator
NYE86_35595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NYE86_35610	COG0653	protein targeting
NYE86_35625	COG0006	proline dipeptidase activity
NYE86_35655	COG2372	response to copper ion
NYE86_35660	COG2837	iron assimilation
NYE86_35670	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NYE86_35675	COG0561	phosphatase activity
NYE86_35690	COG1131	(ABC) transporter
NYE86_35700	COG1131	(ABC) transporter
NYE86_35725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NYE86_35730	COG0702	epimerase
NYE86_35740	COG0561	phosphatase activity
NYE86_35755	COG4988	ABC transporter
NYE86_35760	COG1294	oxidase, subunit
NYE86_35765	COG1271	oxidase subunit
NYE86_35770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NYE86_35775	COG1609	Transcriptional regulator
NYE86_35780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NYE86_35795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NYE86_35810	COG0662	Cupin 2, conserved barrel domain protein
NYE86_35815	COG1950	PFAM Membrane protein of
NYE86_35820	COG0626	cystathionine gamma-synthase activity
NYE86_35850	COG1472	Belongs to the glycosyl hydrolase 3 family
NYE86_35865	COG0305	Participates in initiation and elongation during chromosome replication
NYE86_35875	COG0359	binds to the 23S rRNA
NYE86_35880	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NYE86_35885	COG0629	single-stranded DNA binding
NYE86_35890	COG0360	Binds together with S18 to 16S ribosomal RNA
NYE86_35915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NYE86_35935	COG0617	tRNA 3'-terminal CCA addition
NYE86_35955	COG0515	serine threonine protein kinase
NYE86_35955	COG2815	serine threonine protein kinase
NYE86_35960	COG1595	DNA-templated transcription, initiation
NYE86_35970	COG0492	ferredoxin-NADP+ reductase activity
NYE86_35975	COG3118	belongs to the thioredoxin family
NYE86_35990	COG1192	Involved in chromosome partitioning
NYE86_35995	COG0357	Ribosomal RNA small subunit methyltransferase G
NYE86_36005	COG0706	membrane insertase activity
NYE86_36010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NYE86_36015	COG0594	ribonuclease P activity
NYE86_36020	COG0230	Belongs to the bacterial ribosomal protein bL34 family