TL08_01860 5c7ba75b3d2f279cbeaafa7455263d98 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 122 135 3.0E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_01860 5c7ba75b3d2f279cbeaafa7455263d98 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 3.0E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_01860 5c7ba75b3d2f279cbeaafa7455263d98 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 170 190 3.0E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_01860 5c7ba75b3d2f279cbeaafa7455263d98 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 95 206 8.6E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_01860 5c7ba75b3d2f279cbeaafa7455263d98 235 SUPERFAMILY SSF56784 7 212 4.72E-32 T 12-10-2018 IPR036412 HAD-like superfamily TL08_01860 5c7ba75b3d2f279cbeaafa7455263d98 235 Gene3D G3DSA:3.40.50.1000 4 225 1.2E-28 T 12-10-2018 IPR023214 HAD superfamily TL08_01860 5c7ba75b3d2f279cbeaafa7455263d98 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 73 207 1.1E-11 T 12-10-2018 TL08_01860 5c7ba75b3d2f279cbeaafa7455263d98 235 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 149 200 8.0E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 Gene3D G3DSA:3.30.930.10 13 478 2.3E-207 T 12-10-2018 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 Gene3D G3DSA:3.40.50.800 5 565 2.3E-207 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 581 36.323 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 Pfam PF04073 Aminoacyl-tRNA editing domain 259 387 3.6E-21 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 SUPERFAMILY SSF55681 12 491 5.51E-86 T 12-10-2018 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 SUPERFAMILY SSF52954 477 580 1.52E-28 T 12-10-2018 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 471 4.7E-36 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 1.9E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 1.9E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 1.9E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 1.9E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 Pfam PF03129 Anticodon binding domain 489 578 6.5E-19 T 12-10-2018 IPR004154 Anticodon-binding TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 577 9.3E-166 T 12-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 SUPERFAMILY SSF55826 282 383 5.1E-9 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TL08_09125 9652c4c7e9eb267d9a3032145ed4378d 582 Gene3D G3DSA:3.90.960.10 242 402 2.3E-207 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TL08_11160 9cc373982820abbb8157f2ad1f495234 425 SUPERFAMILY SSF51445 7 323 5.97E-96 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_11160 9cc373982820abbb8157f2ad1f495234 425 Gene3D G3DSA:3.20.20.80 8 323 1.0E-108 T 12-10-2018 TL08_11160 9cc373982820abbb8157f2ad1f495234 425 Pfam PF01120 Alpha-L-fucosidase 7 320 4.9E-87 T 12-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TL08_11160 9cc373982820abbb8157f2ad1f495234 425 PIRSF PIRSF001092 2 390 4.9E-112 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TL08_11160 9cc373982820abbb8157f2ad1f495234 425 SMART SM00812 2 363 2.7E-114 T 12-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TL08_11160 9cc373982820abbb8157f2ad1f495234 425 PRINTS PR00741 Glycosyl hydrolase family 29 signature 273 294 9.9E-22 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TL08_11160 9cc373982820abbb8157f2ad1f495234 425 PRINTS PR00741 Glycosyl hydrolase family 29 signature 117 136 9.9E-22 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TL08_11160 9cc373982820abbb8157f2ad1f495234 425 PRINTS PR00741 Glycosyl hydrolase family 29 signature 72 88 9.9E-22 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TL08_11160 9cc373982820abbb8157f2ad1f495234 425 PRINTS PR00741 Glycosyl hydrolase family 29 signature 306 328 9.9E-22 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TL08_11160 9cc373982820abbb8157f2ad1f495234 425 Gene3D G3DSA:2.60.40.1180 324 386 1.0E-108 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 SMART SM00490 490 576 2.9E-17 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 35 715 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 Hamap MF_00204 UvrABC system protein B [uvrB]. 34 717 42.592 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 Gene3D G3DSA:3.40.50.300 28 271 2.6E-73 T 12-10-2018 TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 SUPERFAMILY SSF52540 64 609 1.97E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 Pfam PF00271 Helicase conserved C-terminal domain 471 574 2.2E-17 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 Pfam PF02151 UvrB/uvrC motif 684 717 4.2E-6 T 12-10-2018 IPR001943 UVR domain GO:0005515 TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 SMART SM00487 40 456 1.3E-24 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 Gene3D G3DSA:3.40.50.300 305 444 6.3E-52 T 12-10-2018 TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 SUPERFAMILY SSF52540 36 445 2.66E-130 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 Pfam PF12344 Ultra-violet resistance protein B 582 623 1.6E-20 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 Pfam PF04851 Type III restriction enzyme, res subunit 46 150 3.6E-8 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 Gene3D G3DSA:3.40.50.300 445 626 2.1E-47 T 12-10-2018 TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 Gene3D G3DSA:4.10.860.10 668 721 8.0E-7 T 12-10-2018 TL08_10280 3c6ee6ef22a760b040ffbe2432245346 727 SUPERFAMILY SSF46600 674 718 6.93E-10 T 12-10-2018 IPR036876 UVR domain superfamily TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 PIRSF PIRSF000343 1 220 1.1E-60 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 Pfam PF01126 Heme oxygenase 10 209 1.9E-50 T 12-10-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 PRINTS PR00088 Haem oxygenase signature 70 95 1.6E-23 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 PRINTS PR00088 Haem oxygenase signature 123 144 1.6E-23 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 PRINTS PR00088 Haem oxygenase signature 197 215 1.6E-23 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 PRINTS PR00088 Haem oxygenase signature 165 186 1.6E-23 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 PRINTS PR00088 Haem oxygenase signature 45 70 1.6E-23 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 PRINTS PR00088 Haem oxygenase signature 10 35 1.6E-23 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 SUPERFAMILY SSF48613 9 215 5.11E-55 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_26555 b87839fe58430e9e9d4f9a0b999ab4c8 230 Gene3D G3DSA:1.20.910.10 9 220 2.3E-62 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 PRINTS PR00173 Glutamate-aspartate symporter signature 202 221 5.5E-28 T 12-10-2018 TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 PRINTS PR00173 Glutamate-aspartate symporter signature 21 41 5.5E-28 T 12-10-2018 TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 PRINTS PR00173 Glutamate-aspartate symporter signature 303 329 5.5E-28 T 12-10-2018 TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 PRINTS PR00173 Glutamate-aspartate symporter signature 338 357 5.5E-28 T 12-10-2018 TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 PRINTS PR00173 Glutamate-aspartate symporter signature 88 113 5.5E-28 T 12-10-2018 TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 PRINTS PR00173 Glutamate-aspartate symporter signature 155 177 5.5E-28 T 12-10-2018 TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 Gene3D G3DSA:1.10.3860.10 14 426 8.6E-109 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 Pfam PF00375 Sodium:dicarboxylate symporter family 23 411 3.3E-97 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 50 65 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site TL08_17275 a3a4659e7d353dc2f8dc7a838fd8709a 470 SUPERFAMILY SSF118215 23 412 3.79E-105 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TL08_12610 c3047a6cc55f7f23b251a8ca2ebf2296 960 SUPERFAMILY SSF52540 1 211 2.92E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12610 c3047a6cc55f7f23b251a8ca2ebf2296 960 SMART SM00421 854 911 5.2E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_12610 c3047a6cc55f7f23b251a8ca2ebf2296 960 Gene3D G3DSA:1.10.10.10 831 913 2.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12610 c3047a6cc55f7f23b251a8ca2ebf2296 960 Pfam PF00196 Bacterial regulatory proteins, luxR family 856 910 5.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_12610 c3047a6cc55f7f23b251a8ca2ebf2296 960 Pfam PF13191 AAA ATPase domain 1 140 5.8E-8 T 12-10-2018 TL08_12610 c3047a6cc55f7f23b251a8ca2ebf2296 960 SUPERFAMILY SSF46894 845 912 9.86E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_12610 c3047a6cc55f7f23b251a8ca2ebf2296 960 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 857 871 1.9E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_12610 c3047a6cc55f7f23b251a8ca2ebf2296 960 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 871 887 1.9E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_12610 c3047a6cc55f7f23b251a8ca2ebf2296 960 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 887 899 1.9E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20440 ae982392e232a8974fc1fbbbb1c41eb8 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 194 3.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20440 ae982392e232a8974fc1fbbbb1c41eb8 216 Gene3D G3DSA:1.10.10.10 140 210 2.8E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_20440 ae982392e232a8974fc1fbbbb1c41eb8 216 SUPERFAMILY SSF46894 136 195 1.19E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_20440 ae982392e232a8974fc1fbbbb1c41eb8 216 SMART SM00421 143 205 4.7E-4 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26725 6551d10f975e95bc97362d4591fe8af9 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 290 2.6E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_26725 6551d10f975e95bc97362d4591fe8af9 309 Gene3D G3DSA:1.10.3720.10 77 294 1.4E-45 T 12-10-2018 IPR035906 MetI-like superfamily TL08_26725 6551d10f975e95bc97362d4591fe8af9 309 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 87 182 2.4E-17 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TL08_26725 6551d10f975e95bc97362d4591fe8af9 309 SUPERFAMILY SSF161098 87 276 1.44E-37 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04640 bc8ff49b721175b261cff48150f237af 216 Gene3D G3DSA:3.40.50.150 7 215 3.7E-57 T 12-10-2018 TL08_04640 bc8ff49b721175b261cff48150f237af 216 Pfam PF01596 O-methyltransferase 41 214 4.1E-27 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 TL08_04640 bc8ff49b721175b261cff48150f237af 216 SUPERFAMILY SSF53335 36 214 1.08E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_15345 7ad32a1edd8b33380293698ec180dcd8 774 SUPERFAMILY SSF50952 104 488 7.72E-13 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TL08_15345 7ad32a1edd8b33380293698ec180dcd8 774 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 642 764 6.9E-7 T 12-10-2018 TL08_15345 7ad32a1edd8b33380293698ec180dcd8 774 Gene3D G3DSA:2.120.10.30 99 487 1.5E-45 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_15345 7ad32a1edd8b33380293698ec180dcd8 774 Gene3D G3DSA:2.60.120.200 580 773 1.3E-12 T 12-10-2018 TL08_15345 7ad32a1edd8b33380293698ec180dcd8 774 SUPERFAMILY SSF49899 500 770 1.62E-15 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TL08_15345 7ad32a1edd8b33380293698ec180dcd8 774 Pfam PF07995 Glucose / Sorbosone dehydrogenase 137 450 6.6E-21 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 Gene3D G3DSA:3.30.465.10 328 418 5.5E-18 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 SUPERFAMILY SSF56176 332 405 1.39E-13 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 Pfam PF01595 Domain of unknown function DUF21 6 181 1.9E-35 T 12-10-2018 IPR002550 CNNM, transmembrane domain TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 Pfam PF03471 Transporter associated domain 338 405 3.1E-12 T 12-10-2018 IPR005170 Transporter-associated domain TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 SMART SM01091 337 419 2.6E-20 T 12-10-2018 IPR005170 Transporter-associated domain TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 Gene3D G3DSA:3.10.580.10 177 327 5.8E-53 T 12-10-2018 TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 Pfam PF00571 CBS domain 197 253 6.2E-7 T 12-10-2018 IPR000644 CBS domain TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 Pfam PF00571 CBS domain 268 321 1.5E-5 T 12-10-2018 IPR000644 CBS domain TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 SUPERFAMILY SSF54631 184 324 7.2E-33 T 12-10-2018 TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 SMART SM00116 273 321 5.7 T 12-10-2018 IPR000644 CBS domain TL08_21375 2ffeb60ec2937691d1bbe514ef49baa0 443 SMART SM00116 206 255 0.092 T 12-10-2018 IPR000644 CBS domain TL08_04230 363815fbb566b0fbd57b9166c35e8d16 1038 Pfam PF13476 AAA domain 5 219 7.8E-22 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain TL08_04230 363815fbb566b0fbd57b9166c35e8d16 1038 Pfam PF13558 Putative exonuclease SbcCD, C subunit 935 996 3.3E-11 T 12-10-2018 TL08_04230 363815fbb566b0fbd57b9166c35e8d16 1038 Gene3D G3DSA:3.40.50.300 804 1036 2.5E-24 T 12-10-2018 TL08_04230 363815fbb566b0fbd57b9166c35e8d16 1038 SUPERFAMILY SSF52540 2 1028 1.35E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04230 363815fbb566b0fbd57b9166c35e8d16 1038 Gene3D G3DSA:3.40.50.300 1 366 2.2E-35 T 12-10-2018 TL08_09905 492fc7070ae5248ba0d58361962f7f68 288 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 278 2.1E-67 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TL08_09905 492fc7070ae5248ba0d58361962f7f68 288 Gene3D G3DSA:3.90.850.10 69 285 1.3E-77 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TL08_09905 492fc7070ae5248ba0d58361962f7f68 288 SUPERFAMILY SSF56529 69 280 1.02E-71 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 PIRSF PIRSF000097 1 271 1.9E-86 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 SUPERFAMILY SSF51430 8 266 5.89E-93 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 Gene3D G3DSA:3.20.20.100 1 273 3.5E-114 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 PRINTS PR00069 Aldo-keto reductase signature 37 61 3.4E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 PRINTS PR00069 Aldo-keto reductase signature 159 188 3.4E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 PRINTS PR00069 Aldo-keto reductase signature 125 142 3.4E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 PRINTS PR00069 Aldo-keto reductase signature 196 220 3.4E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 PRINTS PR00069 Aldo-keto reductase signature 93 111 3.4E-47 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_17740 c95d3a06029c5a1c72ce7dc8a8731c4c 274 Pfam PF00248 Aldo/keto reductase family 24 260 1.6E-48 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_08100 019db477b0403e3c54c800614315a273 883 Gene3D G3DSA:3.40.50.620 33 530 2.1E-291 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_08100 019db477b0403e3c54c800614315a273 883 TIGRFAM TIGR00422 valS: valine--tRNA ligase 14 853 0.0 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_08100 019db477b0403e3c54c800614315a273 883 SUPERFAMILY SSF46589 811 875 5.75E-13 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TL08_08100 019db477b0403e3c54c800614315a273 883 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 811 875 2.7E-19 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 TL08_08100 019db477b0403e3c54c800614315a273 883 Gene3D G3DSA:1.10.287.380 804 876 3.5E-17 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 TL08_08100 019db477b0403e3c54c800614315a273 883 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 65 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_08100 019db477b0403e3c54c800614315a273 883 Hamap MF_02004 Valine--tRNA ligase [valS]. 13 876 15.031 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_08100 019db477b0403e3c54c800614315a273 883 PRINTS PR00986 Valyl-tRNA synthetase signature 47 58 5.1E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_08100 019db477b0403e3c54c800614315a273 883 PRINTS PR00986 Valyl-tRNA synthetase signature 239 256 5.1E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_08100 019db477b0403e3c54c800614315a273 883 PRINTS PR00986 Valyl-tRNA synthetase signature 355 368 5.1E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_08100 019db477b0403e3c54c800614315a273 883 PRINTS PR00986 Valyl-tRNA synthetase signature 480 498 5.1E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_08100 019db477b0403e3c54c800614315a273 883 PRINTS PR00986 Valyl-tRNA synthetase signature 449 470 5.1E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_08100 019db477b0403e3c54c800614315a273 883 SUPERFAMILY SSF47323 581 823 7.29E-49 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_08100 019db477b0403e3c54c800614315a273 883 Gene3D G3DSA:3.90.740.10 186 351 2.1E-291 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TL08_08100 019db477b0403e3c54c800614315a273 883 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 434 6.4E-144 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_08100 019db477b0403e3c54c800614315a273 883 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 446 566 2.6E-45 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_08100 019db477b0403e3c54c800614315a273 883 SUPERFAMILY SSF50677 201 343 7.06E-55 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TL08_08100 019db477b0403e3c54c800614315a273 883 Gene3D G3DSA:1.10.730.10 13 743 2.1E-291 T 12-10-2018 TL08_08100 019db477b0403e3c54c800614315a273 883 SUPERFAMILY SSF52374 12 579 5.2E-132 T 12-10-2018 TL08_08100 019db477b0403e3c54c800614315a273 883 Pfam PF08264 Anticodon-binding domain of tRNA 611 753 1.9E-39 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TL08_08645 1203b1a1287d30c958acf3859e638337 668 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 120 421 2.3E-65 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TL08_08645 1203b1a1287d30c958acf3859e638337 668 Gene3D G3DSA:2.60.120.260 501 655 3.1E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_08645 1203b1a1287d30c958acf3859e638337 668 Gene3D G3DSA:3.40.50.1820 350 482 2.9E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_08645 1203b1a1287d30c958acf3859e638337 668 Gene3D G3DSA:3.40.50.1820 104 336 9.6E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_08645 1203b1a1287d30c958acf3859e638337 668 SUPERFAMILY SSF49785 514 657 4.04E-35 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_08645 1203b1a1287d30c958acf3859e638337 668 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 448 649 2.0E-39 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TL08_08645 1203b1a1287d30c958acf3859e638337 668 SMART SM00939 436 652 1.0E-39 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TL08_08645 1203b1a1287d30c958acf3859e638337 668 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 90 102 2.1E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 TL08_08645 1203b1a1287d30c958acf3859e638337 668 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 106 116 2.1E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 TL08_08645 1203b1a1287d30c958acf3859e638337 668 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 300 316 2.1E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 TL08_08645 1203b1a1287d30c958acf3859e638337 668 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 124 133 2.1E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 TL08_08645 1203b1a1287d30c958acf3859e638337 668 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 141 157 2.1E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 TL08_08645 1203b1a1287d30c958acf3859e638337 668 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 620 635 2.1E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 TL08_08645 1203b1a1287d30c958acf3859e638337 668 SUPERFAMILY SSF53474 90 471 6.85E-76 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07760 69225d2e6fd9df84b39f684732360f19 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 1.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07760 69225d2e6fd9df84b39f684732360f19 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07760 69225d2e6fd9df84b39f684732360f19 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07760 69225d2e6fd9df84b39f684732360f19 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 1.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07760 69225d2e6fd9df84b39f684732360f19 154 Gene3D G3DSA:1.10.10.10 6 152 6.4E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07760 69225d2e6fd9df84b39f684732360f19 154 SMART SM00347 32 135 3.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07760 69225d2e6fd9df84b39f684732360f19 154 Pfam PF12802 MarR family 38 98 4.2E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07760 69225d2e6fd9df84b39f684732360f19 154 SUPERFAMILY SSF46785 5 150 6.75E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF55048 2357 2409 3.53E-8 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5668 5683 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 3166 3187 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.90.180.10 3021 3347 1.2E-121 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.90.180.10 5030 5355 9.2E-119 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.30.70.3290 4170 4566 2.6E-145 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1650 1665 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF51735 1344 1536 1.86E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.50.11460 4859 5026 4.5E-48 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.50.11460 2855 3020 3.9E-47 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3661 3676 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 5174 5195 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF50129 5061 5179 1.07E-26 T 12-10-2018 IPR011032 GroES-like superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1715 1965 1.5E-89 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 5.4E-90 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3726 3976 6.0E-87 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF51735 5145 5282 1.35E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.50.720 5356 5604 5.1E-65 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.50.720 3348 3590 5.5E-65 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF47336 1618 1730 6.94E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF00698 Acyl transferase domain 2246 2529 3.9E-48 T 12-10-2018 IPR014043 Acyl transferase TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF00698 Acyl transferase domain 565 848 8.8E-46 T 12-10-2018 IPR014043 Acyl transferase TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF00698 Acyl transferase domain 4254 4537 1.2E-45 T 12-10-2018 IPR014043 Acyl transferase TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 566 830 4.3E-107 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2247 2511 5.5E-106 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4255 4519 4.3E-107 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF47336 3629 3741 1.57E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.30.70.3290 2160 2558 8.3E-146 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF53901 1711 2086 1.19E-103 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00823 Phosphopantetheine attachment site 5641 5713 1.7E-31 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00823 Phosphopantetheine attachment site 1623 1695 4.3E-31 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00823 Phosphopantetheine attachment site 3634 3706 8.7E-31 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF51735 4856 5026 7.48E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF52151 4251 4507 2.09E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF47336 5635 5717 8.38E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF55048 676 728 5.49E-8 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.47.10 25 471 3.3E-187 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.47.10 1706 2149 4.6E-187 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.47.10 3717 4169 1.9E-184 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF51735 2852 3019 2.76E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2091 2211 6.7E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4102 4219 8.0E-17 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 529 9.7E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF55048 4365 4417 5.49E-8 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3354 3530 4.1E-56 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1345 1521 2.7E-51 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5362 5538 4.4E-48 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF50129 3054 3171 6.13E-27 T 12-10-2018 IPR011032 GroES-like superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM01294 1624 1691 0.001 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM01294 5642 5709 1.0E-4 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM01294 3635 3702 6.9E-4 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00829 3039 3344 2.1E-165 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00829 5047 5352 7.5E-166 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF14765 Polyketide synthase dehydratase 896 1156 7.7E-52 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF14765 Polyketide synthase dehydratase 2577 2845 1.9E-55 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF14765 Polyketide synthase dehydratase 4585 4848 4.2E-57 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3889 3905 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.366.10 564 833 1.9E-145 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.366.10 4253 4522 2.6E-145 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.366.10 2245 2514 8.3E-146 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.40.50.720 1164 1594 2.2E-112 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF53901 3722 4096 1.97E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF52151 2243 2499 6.54E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:1.10.1200.10 5621 5714 5.0E-33 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 5066 5123 3.5E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3058 3114 1.3E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF51735 3138 3275 9.02E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.30.70.3290 479 877 1.9E-145 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF53901 31 405 2.25E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF51735 3352 3564 1.64E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF52151 562 818 2.07E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF08659 KR domain 5362 5536 2.6E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF08659 KR domain 1345 1519 4.7E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF08659 KR domain 3354 3529 9.7E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF00550 Phosphopantetheine attachment site 3636 3701 1.3E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF00550 Phosphopantetheine attachment site 1625 1690 2.2E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF00550 Phosphopantetheine attachment site 5643 5709 9.9E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 1.6E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3984 4099 8.9E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1973 2088 4.5E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1878 1894 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF13602 Zinc-binding dehydrogenase 5222 5352 4.0E-17 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF13602 Zinc-binding dehydrogenase 3214 3344 1.6E-16 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.10.129.110 4574 4853 2.3E-108 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.10.129.110 885 1160 8.9E-102 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:3.10.129.110 2566 2849 4.4E-107 T 12-10-2018 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:1.10.1200.10 1605 1698 1.0E-31 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Gene3D G3DSA:1.10.1200.10 3616 3709 1.8E-32 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00825 Beta-ketoacyl synthase 3728 4152 1.4E-217 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00825 Beta-ketoacyl synthase 36 460 7.3E-219 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00825 Beta-ketoacyl synthase 1717 2141 7.1E-221 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 Pfam PF08990 Erythronolide synthase docking 5 27 9.0E-9 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF51735 5360 5572 9.89E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00826 896 1053 1.3E-71 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00826 2577 2735 1.4E-76 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SMART SM00826 4585 4743 1.2E-83 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16010 8dc20e4f495e1cf7fceb504259e79b86 5797 SUPERFAMILY SSF51735 1165 1332 1.97E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_01660 3b17a1c0b32b93758f6f9d61a0a78beb 182 Pfam PF00156 Phosphoribosyl transferase domain 14 162 2.9E-23 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TL08_01660 3b17a1c0b32b93758f6f9d61a0a78beb 182 SUPERFAMILY SSF53271 3 180 1.84E-54 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_01660 3b17a1c0b32b93758f6f9d61a0a78beb 182 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 176 4.2E-68 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 TL08_01660 3b17a1c0b32b93758f6f9d61a0a78beb 182 Gene3D G3DSA:3.40.50.2020 1 181 1.7E-66 T 12-10-2018 TL08_13015 29d84d383ea974dd93687fbd17c86d63 277 Gene3D G3DSA:3.40.50.300 24 269 3.5E-68 T 12-10-2018 TL08_13015 29d84d383ea974dd93687fbd17c86d63 277 SMART SM00382 53 234 8.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13015 29d84d383ea974dd93687fbd17c86d63 277 Pfam PF00005 ABC transporter 44 183 6.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13015 29d84d383ea974dd93687fbd17c86d63 277 SUPERFAMILY SSF52540 29 239 5.72E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13015 29d84d383ea974dd93687fbd17c86d63 277 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_23610 3f89344376acd7564ad4d1ae9ba85ced 110 Pfam PF01909 Nucleotidyltransferase domain 34 67 5.9E-8 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TL08_23610 3f89344376acd7564ad4d1ae9ba85ced 110 SUPERFAMILY SSF81301 20 109 2.39E-15 T 12-10-2018 TL08_23610 3f89344376acd7564ad4d1ae9ba85ced 110 Gene3D G3DSA:3.30.460.10 16 110 1.4E-19 T 12-10-2018 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 Pfam PF00108 Thiolase, N-terminal domain 5 262 5.6E-97 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 Gene3D G3DSA:3.40.47.10 126 389 3.5E-136 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 Pfam PF02803 Thiolase, C-terminal domain 271 391 9.0E-39 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 SUPERFAMILY SSF53901 272 390 7.4E-34 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.9E-130 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 PIRSF PIRSF000429 2 394 3.6E-112 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 SUPERFAMILY SSF53901 5 270 1.59E-83 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 Gene3D G3DSA:3.40.47.10 5 276 3.5E-136 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_07470 9d564acecf21e04d137ccea1aaabca8d 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.30.70.3290 2016 2448 4.7E-160 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF55048 685 750 4.84E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF51735 2513 2723 1.54E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.47.10 3106 3560 1.5E-181 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1197 1376 8.3E-51 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4564 4744 6.8E-64 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2735 2914 3.7E-55 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF53474 4879 5225 1.54E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00825 Beta-ketoacyl synthase 1572 1996 6.6E-213 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00825 Beta-ketoacyl synthase 37 456 1.6E-206 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00825 Beta-ketoacyl synthase 3117 3545 3.9E-208 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.50.720 4336 4820 1.1E-119 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF53901 1567 1933 1.35E-101 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.50.1820 4948 5229 5.5E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.30.70.3290 3583 4017 1.0E-148 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF55048 3791 3850 2.49E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF51735 4333 4524 2.01E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 191 207 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF47336 3016 3130 2.62E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:1.10.1200.10 1463 1554 8.0E-35 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:1.10.1200.10 4830 4923 3.6E-24 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF51735 4562 4810 2.57E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF101173 3 35 1.18E-6 T 12-10-2018 IPR036299 Polyketide synthase, docking domain superfmaily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1946 2066 2.3E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3495 3631 1.4E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 406 524 8.8E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.30.70.3290 473 909 2.3E-150 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00824 Thioesterase 5006 5224 1.0E-86 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF51735 973 1184 1.38E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1507 1522 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.50.720 926 1446 1.4E-166 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.50.720 2467 2982 8.5E-173 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF52151 2101 2399 3.66E-69 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF08659 KR domain 4564 4742 3.8E-59 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF08659 KR domain 2735 2912 1.2E-60 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF08659 KR domain 1197 1374 4.4E-58 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1570 1818 4.1E-86 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 278 8.0E-83 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3115 3367 9.7E-82 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00698 Acyl transferase domain 2104 2410 5.7E-50 T 12-10-2018 IPR014043 Acyl transferase TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00698 Acyl transferase domain 560 880 1.1E-84 T 12-10-2018 IPR014043 Acyl transferase TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00698 Acyl transferase domain 3667 3988 2.7E-78 T 12-10-2018 IPR014043 Acyl transferase TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.10.129.110 4026 4329 1.6E-99 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF51735 1194 1425 1.16E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 286 403 1.1E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1826 1943 2.8E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3375 3492 5.3E-46 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM01294 3021 3088 9.6E-5 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM01294 1481 1548 1.6E-4 T 12-10-2018 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00823 Phosphopantetheine attachment site 4848 4920 4.7E-21 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00823 Phosphopantetheine attachment site 3020 3092 3.0E-24 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00823 Phosphopantetheine attachment site 1480 1552 2.0E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:1.10.1200.10 2999 3093 3.9E-29 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF51735 2731 2962 4.91E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF52151 3665 3953 6.8E-61 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF55048 2231 2295 7.72E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF53901 3112 3489 2.38E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.47.10 16 457 2.7E-181 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.47.10 1558 1997 5.8E-185 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF53901 32 400 7.17E-101 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF08990 Erythronolide synthase docking 5 28 9.5E-9 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.366.10 3666 3972 1.0E-148 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.366.10 2102 2403 4.7E-160 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Gene3D G3DSA:3.40.366.10 559 864 2.3E-150 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF47336 4844 4935 8.06E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1731 1747 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00975 Thioesterase domain 5004 5223 1.0E-21 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3280 3296 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3668 3969 8.0E-99 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 561 861 2.8E-106 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2104 2400 1.2E-114 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00550 Phosphopantetheine attachment site 1482 1548 1.6E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00550 Phosphopantetheine attachment site 4851 4914 3.2E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF00550 Phosphopantetheine attachment site 3023 3088 6.5E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF47336 1478 1585 1.15E-24 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 Pfam PF14765 Polyketide synthase dehydratase 4037 4324 6.1E-47 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SUPERFAMILY SSF52151 559 848 2.35E-64 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15850 28b580e79b9c6f88b7bb7f377b2ac000 5232 SMART SM00826 4037 4202 1.9E-67 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 Pfam PF01025 GrpE 98 251 1.6E-31 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 Hamap MF_01151 Protein GrpE [grpE]. 11 252 16.007 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 Gene3D G3DSA:3.90.20.20 93 195 4.9E-14 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 SUPERFAMILY SSF58014 109 196 1.7E-15 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 Gene3D G3DSA:2.30.22.10 196 251 4.8E-16 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 SUPERFAMILY SSF51064 198 252 3.4E-14 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 PRINTS PR00773 GrpE protein signature 129 145 1.7E-20 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 PRINTS PR00773 GrpE protein signature 231 250 1.7E-20 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 PRINTS PR00773 GrpE protein signature 204 219 1.7E-20 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 PRINTS PR00773 GrpE protein signature 157 172 1.7E-20 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TL08_26425 6df152ce7173a58cc2146f83f0c1fa10 289 ProSitePatterns PS01071 grpE protein signature. 207 250 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 SMART SM00421 156 218 1.6E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 3.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 3.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 3.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 Gene3D G3DSA:3.40.50.12740 5 216 1.2E-42 T 12-10-2018 TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 SUPERFAMILY SSF52172 3 167 9.95E-18 T 12-10-2018 IPR011006 CheY-like superfamily TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 SMART SM00448 5 128 2.0E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 203 3.3E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 Pfam PF00072 Response regulator receiver domain 7 103 3.1E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_16360 29dde6be379d8f05815e1d819f8fd963 221 SUPERFAMILY SSF46894 152 205 2.55E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 Gene3D G3DSA:3.40.50.2000 461 643 8.5E-36 T 12-10-2018 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 111 712 6.7E-228 T 12-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 PIRSF PIRSF000460 1 800 1.7E-252 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 Pfam PF11897 Protein of unknown function (DUF3417) 13 123 7.0E-34 T 12-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 Pfam PF00343 Carbohydrate phosphorylase 277 624 1.3E-15 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 Pfam PF00343 Carbohydrate phosphorylase 128 173 2.0E-4 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 602 614 - T 12-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 SUPERFAMILY SSF53756 4 746 3.65E-196 T 12-10-2018 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 Gene3D G3DSA:3.40.50.2000 121 195 4.1E-9 T 12-10-2018 TL08_06555 0d3b078f7628fab612b1dffa1e77806a 852 Gene3D G3DSA:3.40.50.2000 265 430 1.5E-14 T 12-10-2018 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 Gene3D G3DSA:3.40.50.1980 29 236 5.5E-61 T 12-10-2018 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 436 38.14 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 435 2.4E-139 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 237 269 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 Pfam PF00815 Histidinol dehydrogenase 22 435 3.6E-154 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 Gene3D G3DSA:3.40.50.1980 237 380 1.9E-48 T 12-10-2018 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 PRINTS PR00083 Histidinol dehydrogenase signature 259 278 1.3E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 1.3E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 1.3E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 PRINTS PR00083 Histidinol dehydrogenase signature 208 233 1.3E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 1.3E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 PRINTS PR00083 Histidinol dehydrogenase signature 237 258 1.3E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 1.3E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 1.3E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 SUPERFAMILY SSF53720 24 435 1.31E-69 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_09680 68317e3caf09017e4b7f7fe0476ea68a 438 PIRSF PIRSF000099 1 437 1.1E-148 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SUPERFAMILY SSF48452 870 1185 5.96E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 Gene3D G3DSA:1.25.40.10 1375 1569 1.8E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 Gene3D G3DSA:1.25.40.10 1570 1716 5.5E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 Gene3D G3DSA:1.25.40.10 1219 1374 1.3E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 Gene3D G3DSA:1.25.40.10 2 270 2.0E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 Gene3D G3DSA:1.25.40.10 276 490 4.1E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 Gene3D G3DSA:1.25.40.10 1067 1214 6.5E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00671 941 972 150.0 T 12-10-2018 IPR006597 Sel1-like repeat TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00671 1538 1569 200.0 T 12-10-2018 IPR006597 Sel1-like repeat TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00671 347 378 110.0 T 12-10-2018 IPR006597 Sel1-like repeat TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00671 1307 1338 100.0 T 12-10-2018 IPR006597 Sel1-like repeat TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00671 1574 1605 30.0 T 12-10-2018 IPR006597 Sel1-like repeat TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00671 1610 1641 59.0 T 12-10-2018 IPR006597 Sel1-like repeat TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SUPERFAMILY SSF81901 18 143 4.71E-6 T 12-10-2018 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SUPERFAMILY SSF81901 172 382 9.94E-17 T 12-10-2018 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SUPERFAMILY SSF81901 1245 1520 1.36E-12 T 12-10-2018 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 680 713 450.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 1087 1120 0.71 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 1682 1715 67.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 275 308 170.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 1307 1340 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 1271 1304 300.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 1431 1464 15.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 1235 1268 400.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 311 344 84.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SMART SM00028 941 974 20.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 Pfam PF13432 Tetratricopeptide repeat 415 466 0.0019 T 12-10-2018 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 Pfam PF13432 Tetratricopeptide repeat 322 378 4.6E-4 T 12-10-2018 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 SUPERFAMILY SSF81901 1516 1713 3.01E-12 T 12-10-2018 TL08_17710 da8078a3138e80c9deab75ae9cb5a303 1727 Gene3D G3DSA:1.25.40.10 864 1049 5.4E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_00365 020665b9ac7c42d9d6d9c8dc3e104649 107 Pfam PF00581 Rhodanese-like domain 12 91 1.5E-14 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_00365 020665b9ac7c42d9d6d9c8dc3e104649 107 Gene3D G3DSA:3.40.250.10 4 100 1.6E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_00365 020665b9ac7c42d9d6d9c8dc3e104649 107 SMART SM00450 1 95 1.1E-23 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_00365 020665b9ac7c42d9d6d9c8dc3e104649 107 SUPERFAMILY SSF52821 4 98 9.43E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 Gene3D G3DSA:3.40.50.620 1 185 1.4E-62 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 SUPERFAMILY SSF82114 174 314 8.5E-40 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 PIRSF PIRSF004491 1 317 3.2E-98 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 Pfam PF01687 Riboflavin kinase 184 313 1.5E-34 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 Pfam PF06574 FAD synthetase 13 166 2.8E-51 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 18 83 3.1E-7 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 SUPERFAMILY SSF52374 16 176 2.35E-34 T 12-10-2018 TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 313 1.3E-72 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 Gene3D G3DSA:2.40.30.30 186 317 5.1E-44 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TL08_09235 08bf5f09a5a2fb6b38901baeca0c00a8 317 SMART SM00904 183 314 7.8E-52 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 Pfam PF00067 Cytochrome P450 223 371 1.6E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 SUPERFAMILY SSF48264 25 406 2.36E-89 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00359 B-class P450 signature 160 175 4.1E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00359 B-class P450 signature 197 219 4.1E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00359 B-class P450 signature 325 340 4.1E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00359 B-class P450 signature 346 355 4.1E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00359 B-class P450 signature 355 366 4.1E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00359 B-class P450 signature 279 290 4.1E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00359 B-class P450 signature 96 107 4.1E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00359 B-class P450 signature 297 324 4.1E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00359 B-class P450 signature 143 159 4.1E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 Gene3D G3DSA:1.10.630.10 20 406 7.9E-118 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00385 P450 superfamily signature 346 355 3.1E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00385 P450 superfamily signature 279 290 3.1E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00385 P450 superfamily signature 242 259 3.1E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 PRINTS PR00385 P450 superfamily signature 355 366 3.1E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16205 f5a44c66e4e276b8e2255cfe5f25fc96 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF53901 31 406 1.28E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF14765 Polyketide synthase dehydratase 2533 2798 1.0E-47 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF14765 Polyketide synthase dehydratase 870 1132 2.2E-41 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF51735 3081 3217 1.06E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.40.366.10 543 812 3.0E-112 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.40.366.10 2178 2470 4.7E-141 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF08659 KR domain 1295 1463 2.6E-50 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF08659 KR domain 3298 3472 1.7E-54 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.40.50.720 3292 3543 1.0E-61 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1595 1610 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00826 2533 2690 1.6E-63 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00826 870 1025 1.2E-50 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF55048 2301 2364 2.09E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.40.50.11460 2804 2961 1.7E-30 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1660 1910 5.2E-90 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.6E-89 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF53901 1657 2029 1.92E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF50129 2985 3119 2.2E-22 T 12-10-2018 IPR011032 GroES-like superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.30.70.3290 476 855 3.0E-112 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.90.180.10 2964 3291 2.7E-114 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF00107 Zinc-binding dehydrogenase 3121 3212 3.0E-14 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3003 3057 3.0E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF52151 543 806 2.49E-58 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.40.50.720 1131 1546 9.8E-92 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF51735 1142 1279 1.54E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF52151 2176 2453 1.67E-66 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.40.47.10 1654 2098 2.2E-180 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF47336 3572 3655 2.49E-20 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF00698 Acyl transferase domain 2179 2452 2.6E-52 T 12-10-2018 IPR014043 Acyl transferase TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF00698 Acyl transferase domain 545 803 2.8E-41 T 12-10-2018 IPR014043 Acyl transferase TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF00550 Phosphopantetheine attachment site 3582 3647 4.0E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF00550 Phosphopantetheine attachment site 1570 1636 4.7E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:1.10.1200.10 3561 3653 2.6E-33 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:1.10.1200.10 1549 1639 2.9E-34 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF51735 2829 2959 3.07E-16 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.10.129.110 863 1130 3.6E-77 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.10.129.110 2523 2801 8.5E-93 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1918 2032 3.2E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 3.5E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.30.70.3290 2100 2515 4.7E-141 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2036 2137 4.8E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 523 1.9E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 3110 3131 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF51735 3298 3547 3.98E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1823 1839 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF51735 1295 1490 6.05E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF55048 652 709 2.62E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00823 Phosphopantetheine attachment site 3580 3652 5.6E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00823 Phosphopantetheine attachment site 1568 1640 6.7E-33 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Pfam PF08990 Erythronolide synthase docking 2 26 5.2E-6 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 545 811 8.2E-84 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2180 2467 6.2E-105 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3607 3622 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3298 3475 4.5E-54 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1295 1465 4.0E-49 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM01294 1569 1636 3.0E-6 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM01294 3581 3648 1.3E-4 T 12-10-2018 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SUPERFAMILY SSF47336 1565 1675 3.8E-25 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 Gene3D G3DSA:3.40.47.10 30 465 1.2E-184 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00829 2983 3288 7.1E-158 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00825 Beta-ketoacyl synthase 1662 2084 1.0E-207 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14650 e28f35757e6eca5135b169cdf587e9e6 3731 SMART SM00825 Beta-ketoacyl synthase 36 460 6.2E-217 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_12040 36be369dc430eebc6bf358b02127c982 598 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 55 576 5.3E-256 T 12-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 TL08_12040 36be369dc430eebc6bf358b02127c982 598 Gene3D G3DSA:1.10.8.60 429 475 2.0E-61 T 12-10-2018 TL08_12040 36be369dc430eebc6bf358b02127c982 598 ProSitePatterns PS00674 AAA-protein family signature. 398 416 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TL08_12040 36be369dc430eebc6bf358b02127c982 598 SMART SM00382 273 430 9.9E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12040 36be369dc430eebc6bf358b02127c982 598 SUPERFAMILY SSF52540 235 547 2.98E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12040 36be369dc430eebc6bf358b02127c982 598 Gene3D G3DSA:3.40.50.300 236 428 2.0E-61 T 12-10-2018 TL08_12040 36be369dc430eebc6bf358b02127c982 598 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 57 577 50.638 T 12-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 TL08_12040 36be369dc430eebc6bf358b02127c982 598 Gene3D G3DSA:2.40.50.140 156 235 3.9E-24 T 12-10-2018 TL08_12040 36be369dc430eebc6bf358b02127c982 598 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 277 428 4.0E-48 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_12040 36be369dc430eebc6bf358b02127c982 598 Pfam PF16450 Proteasomal ATPase OB/ID domain 99 234 2.4E-51 T 12-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain TL08_12040 36be369dc430eebc6bf358b02127c982 598 Gene3D G3DSA:2.40.50.140 96 155 1.9E-27 T 12-10-2018 TL08_12040 36be369dc430eebc6bf358b02127c982 598 Gene3D G3DSA:1.20.5.170 54 95 5.4E-17 T 12-10-2018 TL08_14790 76dc62a934ecc283d0212b84c8ffe1cc 276 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_14790 76dc62a934ecc283d0212b84c8ffe1cc 276 SUPERFAMILY SSF52540 21 251 1.43E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14790 76dc62a934ecc283d0212b84c8ffe1cc 276 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 264 1.3E-7 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_14790 76dc62a934ecc283d0212b84c8ffe1cc 276 Gene3D G3DSA:3.40.50.300 9 275 1.7E-85 T 12-10-2018 TL08_14790 76dc62a934ecc283d0212b84c8ffe1cc 276 Pfam PF00005 ABC transporter 29 179 1.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_14790 76dc62a934ecc283d0212b84c8ffe1cc 276 SMART SM00382 37 229 9.5E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 SMART SM00220 25 286 1.6E-54 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 Gene3D G3DSA:1.10.510.10 110 295 5.8E-50 T 12-10-2018 TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 148 160 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 SUPERFAMILY SSF56112 14 288 8.36E-70 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 Pfam PF03793 PASTA domain 518 582 2.2E-9 T 12-10-2018 IPR005543 PASTA domain TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 Pfam PF03793 PASTA domain 454 513 1.9E-9 T 12-10-2018 IPR005543 PASTA domain TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 Pfam PF03793 PASTA domain 588 651 1.9E-9 T 12-10-2018 IPR005543 PASTA domain TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 Pfam PF00069 Protein kinase domain 26 275 4.7E-44 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 Gene3D G3DSA:3.30.10.20 448 516 3.1E-11 T 12-10-2018 TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 Gene3D G3DSA:3.30.10.20 517 585 6.5E-12 T 12-10-2018 TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 Gene3D G3DSA:3.30.200.20 14 108 2.0E-28 T 12-10-2018 TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 SMART SM00740 584 652 8.9E-8 T 12-10-2018 IPR005543 PASTA domain TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 SMART SM00740 655 712 2.2 T 12-10-2018 IPR005543 PASTA domain TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 SMART SM00740 448 514 1.6E-6 T 12-10-2018 IPR005543 PASTA domain TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 SMART SM00740 515 583 0.11 T 12-10-2018 IPR005543 PASTA domain TL08_21570 4b5a781b8cf90e8fec5cd82c9aa559f1 713 Gene3D G3DSA:3.30.10.20 588 654 7.1E-13 T 12-10-2018 TL08_06295 6d6999cf14e51fcfa573eebdacbc34ed 300 SUPERFAMILY SSF56112 46 294 2.73E-21 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_06295 6d6999cf14e51fcfa573eebdacbc34ed 300 Gene3D G3DSA:3.90.1200.10 111 300 6.7E-7 T 12-10-2018 TL08_14305 5fc467cc13bae397fcec12a5989cc8e3 707 Gene3D G3DSA:3.40.50.300 287 569 4.4E-38 T 12-10-2018 TL08_14305 5fc467cc13bae397fcec12a5989cc8e3 707 SUPERFAMILY SSF52540 279 533 7.17E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14305 5fc467cc13bae397fcec12a5989cc8e3 707 Pfam PF01580 FtsK/SpoIIIE family 344 509 2.6E-7 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TL08_22595 608c8dd49b6919c761816a54fa24f889 478 SUPERFAMILY SSF46785 19 93 5.44E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_22595 608c8dd49b6919c761816a54fa24f889 478 Gene3D G3DSA:3.40.640.10 107 463 2.4E-79 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_22595 608c8dd49b6919c761816a54fa24f889 478 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 89 5.1E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22595 608c8dd49b6919c761816a54fa24f889 478 Gene3D G3DSA:1.10.10.10 16 90 8.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22595 608c8dd49b6919c761816a54fa24f889 478 SUPERFAMILY SSF53383 84 468 1.36E-68 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_22595 608c8dd49b6919c761816a54fa24f889 478 Pfam PF00155 Aminotransferase class I and II 150 430 4.9E-15 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_22595 608c8dd49b6919c761816a54fa24f889 478 SMART SM00345 30 89 1.3E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22595 608c8dd49b6919c761816a54fa24f889 478 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 9.2E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22595 608c8dd49b6919c761816a54fa24f889 478 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 9.2E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_15440 f7fcb2517c0f9ca479e275c75bcbcbe3 356 Pfam PF00331 Glycosyl hydrolase family 10 55 353 4.5E-116 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_15440 f7fcb2517c0f9ca479e275c75bcbcbe3 356 PRINTS PR00134 Glycosyl hydrolase family 10 signature 164 175 3.9E-19 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_15440 f7fcb2517c0f9ca479e275c75bcbcbe3 356 PRINTS PR00134 Glycosyl hydrolase family 10 signature 237 249 3.9E-19 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_15440 f7fcb2517c0f9ca479e275c75bcbcbe3 356 PRINTS PR00134 Glycosyl hydrolase family 10 signature 208 219 3.9E-19 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_15440 f7fcb2517c0f9ca479e275c75bcbcbe3 356 PRINTS PR00134 Glycosyl hydrolase family 10 signature 120 132 3.9E-19 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_15440 f7fcb2517c0f9ca479e275c75bcbcbe3 356 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 271 281 - T 12-10-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_15440 f7fcb2517c0f9ca479e275c75bcbcbe3 356 SUPERFAMILY SSF51445 54 353 1.16E-117 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_15440 f7fcb2517c0f9ca479e275c75bcbcbe3 356 Gene3D G3DSA:3.20.20.80 47 355 3.3E-124 T 12-10-2018 TL08_15440 f7fcb2517c0f9ca479e275c75bcbcbe3 356 SMART SM00633 89 356 5.3E-129 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_13700 aceedfc4af896da742a0a66399bd6755 285 SMART SM00382 47 235 1.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13700 aceedfc4af896da742a0a66399bd6755 285 Pfam PF00005 ABC transporter 39 186 1.7E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13700 aceedfc4af896da742a0a66399bd6755 285 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_13700 aceedfc4af896da742a0a66399bd6755 285 SUPERFAMILY SSF52540 23 247 5.82E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13700 aceedfc4af896da742a0a66399bd6755 285 Gene3D G3DSA:3.40.50.300 16 273 2.4E-65 T 12-10-2018 TL08_17905 a67f459ffa56e69f0b451d7019b7fabd 160 Gene3D G3DSA:3.30.70.1450 86 159 3.3E-18 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TL08_17905 a67f459ffa56e69f0b451d7019b7fabd 160 PIRSF PIRSF005028 1 160 1.4E-50 T 12-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT TL08_17905 a67f459ffa56e69f0b451d7019b7fabd 160 Pfam PF02080 TrkA-C domain 89 157 3.8E-15 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TL08_17905 a67f459ffa56e69f0b451d7019b7fabd 160 SUPERFAMILY SSF116726 84 157 9.94E-17 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 Gene3D G3DSA:3.40.50.1000 10 211 1.1E-37 T 12-10-2018 IPR023214 HAD superfamily TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 1.6E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 160 1.6E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 162 182 1.6E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 8 19 1.6E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 189 202 1.6E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 109 198 3.5E-5 T 12-10-2018 TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 103 199 4.7E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 Gene3D G3DSA:1.10.150.240 22 98 1.1E-37 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TL08_24100 72b3be91de7fd3f7ca74007988daa38d 221 SUPERFAMILY SSF56784 10 208 3.87E-27 T 12-10-2018 IPR036412 HAD-like superfamily TL08_17725 1cb7c54b65fa2440cc91360010058d8a 54 Pfam PF00471 Ribosomal protein L33 9 54 1.0E-16 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17725 1cb7c54b65fa2440cc91360010058d8a 54 Gene3D G3DSA:2.20.28.120 1 54 5.6E-25 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17725 1cb7c54b65fa2440cc91360010058d8a 54 SUPERFAMILY SSF57829 4 54 1.4E-17 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TL08_17725 1cb7c54b65fa2440cc91360010058d8a 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 4.2E-23 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17725 1cb7c54b65fa2440cc91360010058d8a 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.377 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_22830 7716874560c6e30dc25cefbafbcf31d7 99 Gene3D G3DSA:1.10.20.60 2 94 7.0E-23 T 12-10-2018 TL08_22830 7716874560c6e30dc25cefbafbcf31d7 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 5.4E-23 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TL08_22830 7716874560c6e30dc25cefbafbcf31d7 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.554 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TL08_22830 7716874560c6e30dc25cefbafbcf31d7 99 SUPERFAMILY SSF141000 3 94 3.79E-28 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 TL08_22830 7716874560c6e30dc25cefbafbcf31d7 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 2.8E-16 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TL08_20345 b4f9cbb2cebbaa7bc5a853411ed21664 275 Pfam PF01975 Survival protein SurE 3 179 6.0E-40 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TL08_20345 b4f9cbb2cebbaa7bc5a853411ed21664 275 Gene3D G3DSA:3.40.1210.10 1 256 1.1E-53 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TL08_20345 b4f9cbb2cebbaa7bc5a853411ed21664 275 SUPERFAMILY SSF64167 2 237 1.7E-41 T 12-10-2018 TL08_11870 45ba623b767a8b086d24161d66a9659d 300 Gene3D G3DSA:1.10.260.40 25 96 8.1E-7 T 12-10-2018 TL08_11870 45ba623b767a8b086d24161d66a9659d 300 Gene3D G3DSA:3.30.450.180 110 285 6.3E-13 T 12-10-2018 TL08_11870 45ba623b767a8b086d24161d66a9659d 300 SUPERFAMILY SSF47413 30 76 5.93E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_11870 45ba623b767a8b086d24161d66a9659d 300 Pfam PF13560 Helix-turn-helix domain 7 86 3.7E-16 T 12-10-2018 TL08_11870 45ba623b767a8b086d24161d66a9659d 300 SMART SM00530 10 83 2.8E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_22835 ec6afbef495db2805cdca84e4e4cb839 241 SUPERFAMILY SSF55021 27 87 1.04E-5 T 12-10-2018 TL08_11835 ad3ca5bdbfd0c32c297807c76c7e3595 139 SUPERFAMILY SSF117916 37 133 1.31E-26 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TL08_11835 ad3ca5bdbfd0c32c297807c76c7e3595 139 Gene3D G3DSA:3.30.300.130 31 134 2.5E-30 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TL08_11835 ad3ca5bdbfd0c32c297807c76c7e3595 139 Pfam PF01883 Iron-sulfur cluster assembly protein 37 102 1.1E-19 T 12-10-2018 IPR002744 MIP18 family-like TL08_00145 49c9ae198c10864f0e25d1cb4f3204fe 151 SMART SM00240 78 128 2.7E-13 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TL08_00145 49c9ae198c10864f0e25d1cb4f3204fe 151 Gene3D G3DSA:2.60.200.20 43 151 3.1E-26 T 12-10-2018 TL08_00145 49c9ae198c10864f0e25d1cb4f3204fe 151 SUPERFAMILY SSF49879 48 150 1.82E-24 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TL08_00145 49c9ae198c10864f0e25d1cb4f3204fe 151 Pfam PF00498 FHA domain 79 142 1.0E-14 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TL08_20230 2afec4820471506391e6694aca373bab 681 Gene3D G3DSA:2.60.120.260 357 541 6.5E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_20230 2afec4820471506391e6694aca373bab 681 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 315 530 6.6E-52 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TL08_20230 2afec4820471506391e6694aca373bab 681 Gene3D G3DSA:3.40.50.1820 17 303 4.2E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_20230 2afec4820471506391e6694aca373bab 681 SUPERFAMILY SSF49785 293 537 1.15E-57 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_20230 2afec4820471506391e6694aca373bab 681 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 23 274 1.1E-60 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TL08_20230 2afec4820471506391e6694aca373bab 681 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 20 512 6.8E-59 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 TL08_20230 2afec4820471506391e6694aca373bab 681 Gene3D G3DSA:1.10.3020.10 154 227 4.2E-58 T 12-10-2018 TL08_20230 2afec4820471506391e6694aca373bab 681 SMART SM00939 291 556 7.0E-73 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TL08_20230 2afec4820471506391e6694aca373bab 681 SUPERFAMILY SSF53474 7 345 1.39E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14215 e1b66999a26ed799a5323c99cb2c5739 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 38 255 2.4E-44 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 TL08_14215 e1b66999a26ed799a5323c99cb2c5739 277 Gene3D G3DSA:3.40.50.150 71 274 1.1E-45 T 12-10-2018 TL08_14215 e1b66999a26ed799a5323c99cb2c5739 277 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 13 275 3.2E-119 T 12-10-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase TL08_14215 e1b66999a26ed799a5323c99cb2c5739 277 Gene3D G3DSA:1.10.8.10 18 70 1.1E-5 T 12-10-2018 TL08_14215 e1b66999a26ed799a5323c99cb2c5739 277 Pfam PF05175 Methyltransferase small domain 109 188 1.8E-9 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TL08_14215 e1b66999a26ed799a5323c99cb2c5739 277 SUPERFAMILY SSF53335 49 241 5.58E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_05065 aea4f78473539b65443670a41abad435 596 SMART SM00823 Phosphopantetheine attachment site 492 561 0.0058 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_05065 aea4f78473539b65443670a41abad435 596 Gene3D G3DSA:3.30.559.30 206 452 1.1E-117 T 12-10-2018 TL08_05065 aea4f78473539b65443670a41abad435 596 Gene3D G3DSA:1.10.1200.10 485 564 1.4E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_05065 aea4f78473539b65443670a41abad435 596 SUPERFAMILY SSF52777 208 455 4.22E-51 T 12-10-2018 TL08_05065 aea4f78473539b65443670a41abad435 596 SUPERFAMILY SSF52777 25 202 1.45E-39 T 12-10-2018 TL08_05065 aea4f78473539b65443670a41abad435 596 Gene3D G3DSA:3.30.559.10 24 393 1.1E-117 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_05065 aea4f78473539b65443670a41abad435 596 SUPERFAMILY SSF47336 488 558 3.17E-14 T 12-10-2018 IPR036736 ACP-like superfamily TL08_05065 aea4f78473539b65443670a41abad435 596 Pfam PF00668 Condensation domain 23 455 9.0E-67 T 12-10-2018 IPR001242 Condensation domain TL08_05065 aea4f78473539b65443670a41abad435 596 Pfam PF00550 Phosphopantetheine attachment site 495 556 8.2E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_02960 335183f361680ee2cd9538c9081c1989 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.759 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TL08_02960 335183f361680ee2cd9538c9081c1989 156 SUPERFAMILY SSF47973 1 149 1.02E-56 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TL08_02960 335183f361680ee2cd9538c9081c1989 156 PIRSF PIRSF002122 5 156 2.8E-55 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 TL08_02960 335183f361680ee2cd9538c9081c1989 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_02960 335183f361680ee2cd9538c9081c1989 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.4E-59 T 12-10-2018 IPR023798 Ribosomal protein S7 domain TL08_02960 335183f361680ee2cd9538c9081c1989 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 7.7E-65 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TL08_02960 335183f361680ee2cd9538c9081c1989 156 Gene3D G3DSA:1.10.455.10 2 156 1.7E-56 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TL08_09240 7d261b36c0218cd11b2ca18473444279 158 SUPERFAMILY SSF47413 21 60 3.56E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_09240 7d261b36c0218cd11b2ca18473444279 158 Gene3D G3DSA:1.10.260.40 19 84 9.3E-6 T 12-10-2018 TL08_24320 ee2ea166a11e36708880e8771ec41673 319 SUPERFAMILY SSF46785 1 83 8.28E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_24320 ee2ea166a11e36708880e8771ec41673 319 SUPERFAMILY SSF46689 100 159 3.28E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_24320 ee2ea166a11e36708880e8771ec41673 319 SUPERFAMILY SSF48498 168 313 1.89E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_24320 ee2ea166a11e36708880e8771ec41673 319 Gene3D G3DSA:1.10.357.10 158 312 1.1E-35 T 12-10-2018 TL08_24320 ee2ea166a11e36708880e8771ec41673 319 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 1.1E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_24320 ee2ea166a11e36708880e8771ec41673 319 Gene3D G3DSA:1.10.10.10 1 74 4.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_24320 ee2ea166a11e36708880e8771ec41673 319 SMART SM00345 14 73 4.9E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_24320 ee2ea166a11e36708880e8771ec41673 319 Pfam PF00440 Bacterial regulatory proteins, tetR family 106 148 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_24320 ee2ea166a11e36708880e8771ec41673 319 Gene3D G3DSA:1.10.10.60 98 157 3.7E-28 T 12-10-2018 TL08_24320 ee2ea166a11e36708880e8771ec41673 319 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 162 310 3.3E-17 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 TL08_02595 22a02fca21ffbaeb79207fb8f1e308e7 214 Gene3D G3DSA:3.40.50.150 4 212 1.3E-53 T 12-10-2018 TL08_02595 22a02fca21ffbaeb79207fb8f1e308e7 214 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 212 30.747 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TL08_02595 22a02fca21ffbaeb79207fb8f1e308e7 214 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 211 3.6E-51 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TL08_02595 22a02fca21ffbaeb79207fb8f1e308e7 214 SUPERFAMILY SSF53335 1 208 3.1E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_02595 22a02fca21ffbaeb79207fb8f1e308e7 214 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 1 210 6.2E-64 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TL08_02595 22a02fca21ffbaeb79207fb8f1e308e7 214 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 120 134 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TL08_17420 3eed9e491fd0af82bc0f66b5ca018fe5 304 Pfam PF01738 Dienelactone hydrolase family 98 227 5.0E-5 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TL08_17420 3eed9e491fd0af82bc0f66b5ca018fe5 304 SUPERFAMILY SSF53474 59 289 9.92E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_17420 3eed9e491fd0af82bc0f66b5ca018fe5 304 Gene3D G3DSA:3.40.50.1820 40 304 1.1E-84 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15445 9f703fbf6f98290dc0a696a121256640 350 Pfam PF13377 Periplasmic binding protein-like domain 182 343 4.4E-44 T 12-10-2018 TL08_15445 9f703fbf6f98290dc0a696a121256640 350 Gene3D G3DSA:3.40.50.2300 175 303 3.7E-74 T 12-10-2018 TL08_15445 9f703fbf6f98290dc0a696a121256640 350 Gene3D G3DSA:3.40.50.2300 82 335 3.7E-74 T 12-10-2018 TL08_15445 9f703fbf6f98290dc0a696a121256640 350 SUPERFAMILY SSF53822 75 347 4.88E-79 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_15445 9f703fbf6f98290dc0a696a121256640 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 62 1.8E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_15445 9f703fbf6f98290dc0a696a121256640 350 Gene3D G3DSA:1.10.260.40 11 73 3.1E-15 T 12-10-2018 TL08_15445 9f703fbf6f98290dc0a696a121256640 350 SMART SM00354 17 84 1.5E-7 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_15445 9f703fbf6f98290dc0a696a121256640 350 SUPERFAMILY SSF47413 17 70 5.81E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_00375 2daa69fb158e306cbd86e32f7f38897d 172 SUPERFAMILY SSF88659 99 159 7.1E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_00375 2daa69fb158e306cbd86e32f7f38897d 172 Pfam PF08281 Sigma-70, region 4 102 155 1.1E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_00375 2daa69fb158e306cbd86e32f7f38897d 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 158 2.5E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_00375 2daa69fb158e306cbd86e32f7f38897d 172 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 8 160 3.0E-45 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 TL08_00375 2daa69fb158e306cbd86e32f7f38897d 172 SUPERFAMILY SSF88946 10 76 1.69E-8 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_00375 2daa69fb158e306cbd86e32f7f38897d 172 Gene3D G3DSA:1.10.10.10 86 161 2.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_00375 2daa69fb158e306cbd86e32f7f38897d 172 Pfam PF04542 Sigma-70 region 2 22 79 2.8E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_00375 2daa69fb158e306cbd86e32f7f38897d 172 Gene3D G3DSA:1.10.1740.10 4 81 3.6E-7 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2347 2778 3.6E-117 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF53901 9 436 3.04E-96 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 549 846 1.8E-99 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF53474 2941 3159 4.27E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:1.20.890.40 3044 3096 6.0E-58 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:1.10.1200.10 1745 1817 4.2E-9 T 12-10-2018 IPR036736 ACP-like superfamily TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF52777 2027 2270 2.22E-56 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.40.50.720 1199 1726 6.3E-110 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 175 191 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SMART SM00826 907 1066 4.1E-39 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF00698 Acyl transferase domain 547 862 3.5E-70 T 12-10-2018 IPR014043 Acyl transferase TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SMART SM00824 Thioesterase 2954 3148 3.1E-5 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.40.47.10 2 456 1.2E-187 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.30.70.3290 458 892 1.2E-133 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 391 503 6.2E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.40.50.1820 2945 3158 6.0E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.40.366.10 547 849 1.2E-133 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF00550 Phosphopantetheine attachment site 1750 1805 1.6E-6 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF00550 Phosphopantetheine attachment site 2867 2926 4.9E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF00501 AMP-binding enzyme 2311 2754 1.4E-89 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF52151 546 834 5.23E-63 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:1.10.1200.10 2854 2931 5.4E-17 T 12-10-2018 IPR036736 ACP-like superfamily TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.30.300.30 2749 2853 1.7E-31 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF47336 2855 2928 5.23E-15 T 12-10-2018 IPR036736 ACP-like superfamily TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF55048 672 736 9.16E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 262 1.4E-79 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1774 1789 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF51735 1453 1714 8.29E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF47336 1747 1816 1.44E-9 T 12-10-2018 IPR036736 ACP-like superfamily TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SMART SM00825 Beta-ketoacyl synthase 13 440 3.1E-208 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1457 1651 4.3E-41 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 270 387 8.4E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF56801 2271 2870 3.66E-147 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.10.129.110 906 1186 1.0E-66 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.30.559.30 2025 2270 7.4E-125 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SMART SM00823 Phosphopantetheine attachment site 1748 1819 3.5E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SMART SM00823 Phosphopantetheine attachment site 2863 2932 0.0013 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF00668 Condensation domain 1843 2287 9.8E-100 T 12-10-2018 IPR001242 Condensation domain TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.40.50.12780 2299 2746 2.6E-115 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF08659 KR domain 1457 1649 4.7E-56 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF00975 Thioesterase domain 2951 3146 2.4E-22 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF14765 Polyketide synthase dehydratase 907 1188 2.6E-70 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Gene3D G3DSA:3.30.559.10 1845 2214 7.4E-125 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2486 2497 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF52777 1846 2021 6.45E-40 T 12-10-2018 TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 Pfam PF13193 AMP-binding enzyme C-terminal domain 2762 2837 2.5E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_13540 d2a69b1bf9062bc27fa294471dc3a502 3167 SUPERFAMILY SSF51735 1196 1440 1.26E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_13950 cf12298d2f31c42df923f5df88da094c 335 Gene3D G3DSA:1.10.443.10 132 318 5.6E-31 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TL08_13950 cf12298d2f31c42df923f5df88da094c 335 SUPERFAMILY SSF56349 18 319 1.21E-34 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_13950 cf12298d2f31c42df923f5df88da094c 335 Gene3D G3DSA:1.10.150.130 20 114 2.8E-6 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_13950 cf12298d2f31c42df923f5df88da094c 335 Pfam PF00589 Phage integrase family 151 310 5.3E-20 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_20170 cbd89165433ed1fc3f2f869eaa620fad 379 PIRSF PIRSF000443 25 379 3.6E-123 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TL08_20170 cbd89165433ed1fc3f2f869eaa620fad 379 Gene3D G3DSA:1.10.1740.110 196 300 1.1E-130 T 12-10-2018 TL08_20170 cbd89165433ed1fc3f2f869eaa620fad 379 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 34 375 6.2E-133 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TL08_20170 cbd89165433ed1fc3f2f869eaa620fad 379 Gene3D G3DSA:3.40.50.1820 37 369 1.1E-130 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_20170 cbd89165433ed1fc3f2f869eaa620fad 379 Pfam PF00561 alpha/beta hydrolase fold 61 362 2.0E-33 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_20170 cbd89165433ed1fc3f2f869eaa620fad 379 SUPERFAMILY SSF53474 36 376 1.31E-93 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_20170 cbd89165433ed1fc3f2f869eaa620fad 379 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 6 376 30.536 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TL08_00400 287c7c5cb815f72507cc0fefca133250 274 SMART SM00850 164 263 2.0E-28 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 TL08_00400 287c7c5cb815f72507cc0fefca133250 274 Gene3D G3DSA:2.40.50.40 156 223 2.0E-9 T 12-10-2018 TL08_00400 287c7c5cb815f72507cc0fefca133250 274 SUPERFAMILY SSF52172 10 146 1.04E-22 T 12-10-2018 IPR011006 CheY-like superfamily TL08_00400 287c7c5cb815f72507cc0fefca133250 274 SMART SM00448 10 134 3.3E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_00400 287c7c5cb815f72507cc0fefca133250 274 Pfam PF00072 Response regulator receiver domain 12 134 7.6E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_00400 287c7c5cb815f72507cc0fefca133250 274 Pfam PF04397 LytTr DNA-binding domain 166 262 9.3E-23 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 TL08_00400 287c7c5cb815f72507cc0fefca133250 274 Gene3D G3DSA:3.40.50.2300 6 146 1.9E-22 T 12-10-2018 TL08_19610 2afb0d9d9370150b4483a0f9653eb838 1188 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1063 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_19610 2afb0d9d9370150b4483a0f9653eb838 1188 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 321 761 1.3E-160 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_19610 2afb0d9d9370150b4483a0f9653eb838 1188 Gene3D G3DSA:3.20.20.140 2 296 4.6E-93 T 12-10-2018 TL08_19610 2afb0d9d9370150b4483a0f9653eb838 1188 SUPERFAMILY SSF89550 5 273 1.69E-28 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TL08_19610 2afb0d9d9370150b4483a0f9653eb838 1188 Gene3D G3DSA:1.10.10.1600 454 543 7.3E-15 T 12-10-2018 TL08_19610 2afb0d9d9370150b4483a0f9653eb838 1188 SMART SM00481 6 73 1.2E-32 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TL08_19610 2afb0d9d9370150b4483a0f9653eb838 1188 Pfam PF02811 PHP domain 7 199 8.4E-50 T 12-10-2018 IPR004013 PHP domain GO:0003824 TL08_19610 2afb0d9d9370150b4483a0f9653eb838 1188 Pfam PF14579 Helix-hairpin-helix motif 835 923 2.7E-25 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_19610 2afb0d9d9370150b4483a0f9653eb838 1188 Pfam PF01336 OB-fold nucleic acid binding domain 1026 1096 2.2E-6 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TL08_15040 6d259fabb94427fe9b35d0179f8e8618 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 300 7.9E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_15040 6d259fabb94427fe9b35d0179f8e8618 308 Gene3D G3DSA:1.10.3720.10 66 305 1.1E-52 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15040 6d259fabb94427fe9b35d0179f8e8618 308 SUPERFAMILY SSF161098 69 295 1.06E-47 T 12-10-2018 IPR035906 MetI-like superfamily TL08_22495 5e1c977e76025c8f4511601d4124e6b2 221 SMART SM00345 15 72 7.2E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22495 5e1c977e76025c8f4511601d4124e6b2 221 SUPERFAMILY SSF48008 77 212 2.14E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_22495 5e1c977e76025c8f4511601d4124e6b2 221 Pfam PF07729 FCD domain 82 203 7.5E-26 T 12-10-2018 IPR011711 GntR, C-terminal TL08_22495 5e1c977e76025c8f4511601d4124e6b2 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 69 1.5E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22495 5e1c977e76025c8f4511601d4124e6b2 221 SUPERFAMILY SSF46785 9 76 1.17E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_22495 5e1c977e76025c8f4511601d4124e6b2 221 SMART SM00895 82 205 2.6E-19 T 12-10-2018 IPR011711 GntR, C-terminal TL08_22495 5e1c977e76025c8f4511601d4124e6b2 221 Gene3D G3DSA:1.10.10.10 2 73 3.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22495 5e1c977e76025c8f4511601d4124e6b2 221 Gene3D G3DSA:1.20.120.530 77 218 1.5E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_21555 ba51fa07f6b6cf85632098902425db9f 383 SUPERFAMILY SSF48576 30 382 8.87E-73 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_21555 ba51fa07f6b6cf85632098902425db9f 383 Gene3D G3DSA:1.10.600.10 19 383 1.1E-111 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_21555 ba51fa07f6b6cf85632098902425db9f 383 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 113 127 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TL08_21555 ba51fa07f6b6cf85632098902425db9f 383 Pfam PF00348 Polyprenyl synthetase 62 320 1.3E-45 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TL08_02885 3ab2bd913f429c000eb37285e96366a2 238 PIRSF PIRSF002155 1 227 3.2E-73 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_02885 3ab2bd913f429c000eb37285e96366a2 238 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 5.6E-100 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TL08_02885 3ab2bd913f429c000eb37285e96366a2 238 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 5.7E-51 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TL08_02885 3ab2bd913f429c000eb37285e96366a2 238 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_02885 3ab2bd913f429c000eb37285e96366a2 238 SUPERFAMILY SSF56808 6 227 3.53E-80 T 12-10-2018 IPR023674 Ribosomal protein L1-like TL08_02885 3ab2bd913f429c000eb37285e96366a2 238 Gene3D G3DSA:3.40.50.790 68 159 2.1E-79 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TL08_02885 3ab2bd913f429c000eb37285e96366a2 238 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.541 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TL08_02885 3ab2bd913f429c000eb37285e96366a2 238 Gene3D G3DSA:3.30.190.20 21 225 2.1E-79 T 12-10-2018 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 Gene3D G3DSA:3.40.50.12740 5 218 9.8E-68 T 12-10-2018 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 SUPERFAMILY SSF52172 4 139 7.97E-31 T 12-10-2018 IPR011006 CheY-like superfamily TL08_06830 6467e656d0d450d565d00c422e6b3297 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 3.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 3.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 3.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 SMART SM00421 155 212 3.4E-27 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 SMART SM00448 5 120 3.2E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 9.3E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 SUPERFAMILY SSF46894 151 218 7.82E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_06830 6467e656d0d450d565d00c422e6b3297 219 Pfam PF00072 Response regulator receiver domain 7 119 3.3E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_15755 11d6eb8a0a97bc7a9c7428b96e706067 366 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 126 1.9E-10 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TL08_15755 11d6eb8a0a97bc7a9c7428b96e706067 366 SUPERFAMILY SSF54826 9 130 1.29E-24 T 12-10-2018 TL08_15755 11d6eb8a0a97bc7a9c7428b96e706067 366 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 101 126 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TL08_15755 11d6eb8a0a97bc7a9c7428b96e706067 366 Pfam PF13378 Enolase C-terminal domain-like 150 358 7.8E-50 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_15755 11d6eb8a0a97bc7a9c7428b96e706067 366 Gene3D G3DSA:3.20.20.120 119 356 4.2E-110 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_15755 11d6eb8a0a97bc7a9c7428b96e706067 366 Gene3D G3DSA:3.30.390.10 18 118 4.2E-110 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_15755 11d6eb8a0a97bc7a9c7428b96e706067 366 SUPERFAMILY SSF51604 114 365 2.36E-55 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_15755 11d6eb8a0a97bc7a9c7428b96e706067 366 SMART SM00922 146 246 5.2E-17 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_10975 3a591f92edcdfd4b637788a95361c451 240 Gene3D G3DSA:3.40.50.12500 2 235 4.3E-53 T 12-10-2018 TL08_10975 3a591f92edcdfd4b637788a95361c451 240 PIRSF PIRSF015736 3 239 8.6E-51 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase TL08_10975 3a591f92edcdfd4b637788a95361c451 240 Pfam PF01177 Asp/Glu/Hydantoin racemase 53 218 8.0E-7 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_08760 1cb62f28c2f16dfcf6ed53af8eac282b 150 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 4.8E-29 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08760 1cb62f28c2f16dfcf6ed53af8eac282b 150 Gene3D G3DSA:3.30.1320.10 1 148 2.3E-28 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08760 1cb62f28c2f16dfcf6ed53af8eac282b 150 Pfam PF00886 Ribosomal protein S16 9 67 3.1E-22 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08760 1cb62f28c2f16dfcf6ed53af8eac282b 150 SUPERFAMILY SSF54565 2 90 4.84E-31 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08760 1cb62f28c2f16dfcf6ed53af8eac282b 150 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.449 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_05640 c9e027b0c46ca0e13d6ebab368606bdb 369 Gene3D G3DSA:3.40.640.10 3 244 4.1E-78 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_05640 c9e027b0c46ca0e13d6ebab368606bdb 369 Gene3D G3DSA:3.90.1150.10 247 367 2.9E-36 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_05640 c9e027b0c46ca0e13d6ebab368606bdb 369 PIRSF PIRSF000390 5 368 3.1E-101 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TL08_05640 c9e027b0c46ca0e13d6ebab368606bdb 369 SUPERFAMILY SSF53383 8 366 1.15E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_05640 c9e027b0c46ca0e13d6ebab368606bdb 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 363 8.9E-111 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TL08_06900 07a934abf30edbcbbf183e7023d56b9f 337 Gene3D G3DSA:2.40.128.290 2 79 1.3E-36 T 12-10-2018 IPR038646 Atu4866-like superfamily TL08_06900 07a934abf30edbcbbf183e7023d56b9f 337 Gene3D G3DSA:2.40.128.290 245 320 4.8E-32 T 12-10-2018 IPR038646 Atu4866-like superfamily TL08_06900 07a934abf30edbcbbf183e7023d56b9f 337 SUPERFAMILY SSF51338 98 205 3.18E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_06900 07a934abf30edbcbbf183e7023d56b9f 337 Gene3D G3DSA:2.30.40.10 103 182 4.8E-9 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_06900 07a934abf30edbcbbf183e7023d56b9f 337 Pfam PF11512 Agrobacterium tumefaciens protein Atu4866 248 318 3.6E-33 T 12-10-2018 IPR020955 Uncharacterised protein family Atu4866 TL08_06900 07a934abf30edbcbbf183e7023d56b9f 337 Pfam PF11512 Agrobacterium tumefaciens protein Atu4866 4 77 1.2E-37 T 12-10-2018 IPR020955 Uncharacterised protein family Atu4866 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:1.10.1200.10 2533 2613 5.0E-25 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.30 3865 4152 8.5E-70 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.30 1270 1540 1.9E-78 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.30 221 466 7.8E-149 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 40 217 6.0E-52 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00550 Phosphopantetheine attachment site 1018 1079 2.1E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00550 Phosphopantetheine attachment site 3615 3677 2.0E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00550 Phosphopantetheine attachment site 2543 2608 2.7E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.40.50.12780 3095 3498 3.8E-132 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.10 40 410 7.8E-149 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.300.30 899 1005 7.2E-36 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.300.30 3499 3608 3.4E-32 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.300.30 2423 2532 1.9E-31 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 3884 4152 2.56E-35 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.40.50.12780 2025 2422 7.2E-149 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 1099 1274 1.06E-33 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3242 3253 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00501 AMP-binding enzyme 511 905 3.5E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00501 AMP-binding enzyme 2034 2430 2.9E-107 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00501 AMP-binding enzyme 3101 3505 2.4E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 2824 3085 1.56E-55 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.10 1090 1269 1.6E-47 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.10 3681 3864 7.1E-50 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF47336 3607 3677 2.22E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.10 2640 3010 1.0E-135 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.40.50.12780 500 898 1.6E-131 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 1755 2019 2.11E-57 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 224 464 5.89E-60 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SMART SM01294 2542 2608 0.0053 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 ProSitePatterns PS00455 Putative AMP-binding domain signature. 653 664 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.30 1755 2010 7.6E-129 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1409 1563 4.0E-40 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF56801 1992 2554 4.06E-170 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:1.10.1200.10 3609 3680 6.2E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:1.10.1200.10 1009 1080 2.1E-19 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2054 2450 2.1E-140 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3122 3527 1.6E-123 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 532 928 1.9E-128 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 1570 1769 1.17E-38 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3640 3655 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF47336 2535 2651 7.33E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00668 Condensation domain 3694 4154 3.5E-54 T 12-10-2018 IPR001242 Condensation domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00668 Condensation domain 1570 2013 9.8E-83 T 12-10-2018 IPR001242 Condensation domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00668 Condensation domain 2638 3081 5.1E-95 T 12-10-2018 IPR001242 Condensation domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00668 Condensation domain 1100 1546 6.0E-75 T 12-10-2018 IPR001242 Condensation domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF00668 Condensation domain 35 478 7.9E-103 T 12-10-2018 IPR001242 Condensation domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.30 2821 3064 1.0E-135 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF47336 1010 1112 1.96E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Gene3D G3DSA:3.30.559.10 1576 1945 7.6E-129 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF56801 3060 3627 1.05E-154 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF13193 AMP-binding enzyme C-terminal domain 913 988 3.2E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF13193 AMP-binding enzyme C-terminal domain 2438 2513 2.9E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 Pfam PF13193 AMP-binding enzyme C-terminal domain 3513 3587 3.3E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SMART SM00823 Phosphopantetheine attachment site 3614 3684 0.0018 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SMART SM00823 Phosphopantetheine attachment site 1016 1086 0.027 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SMART SM00823 Phosphopantetheine attachment site 2541 2612 1.3E-10 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 3693 3869 5.56E-35 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 1286 1539 2.56E-39 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF52777 2640 2817 1.22E-45 T 12-10-2018 TL08_16325 71d0def791323e0a1875cb13ebed03a2 4160 SUPERFAMILY SSF56801 460 1028 5.63E-147 T 12-10-2018 TL08_25770 bc9fc54614494572042ebe21ed444005 315 Gene3D G3DSA:3.40.50.1820 7 305 3.5E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_25770 bc9fc54614494572042ebe21ed444005 315 SUPERFAMILY SSF53474 11 303 2.03E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_25770 bc9fc54614494572042ebe21ed444005 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 6.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_25770 bc9fc54614494572042ebe21ed444005 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 6.9E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_25770 bc9fc54614494572042ebe21ed444005 315 Pfam PF00561 alpha/beta hydrolase fold 24 122 3.6E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_07990 f252b0af1a2635013d2dfdf1ab900fbb 348 Pfam PF00005 ABC transporter 18 166 1.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_07990 f252b0af1a2635013d2dfdf1ab900fbb 348 Pfam PF03459 TOBE domain 286 344 3.8E-5 T 12-10-2018 IPR005116 Transport-associated OB, type 1 TL08_07990 f252b0af1a2635013d2dfdf1ab900fbb 348 SMART SM00382 25 223 5.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_07990 f252b0af1a2635013d2dfdf1ab900fbb 348 SUPERFAMILY SSF50331 252 346 2.11E-10 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TL08_07990 f252b0af1a2635013d2dfdf1ab900fbb 348 Gene3D G3DSA:2.40.50.140 257 345 7.0E-6 T 12-10-2018 TL08_07990 f252b0af1a2635013d2dfdf1ab900fbb 348 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_07990 f252b0af1a2635013d2dfdf1ab900fbb 348 Gene3D G3DSA:2.40.50.100 275 341 7.0E-6 T 12-10-2018 TL08_07990 f252b0af1a2635013d2dfdf1ab900fbb 348 SUPERFAMILY SSF52540 8 240 8.62E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07990 f252b0af1a2635013d2dfdf1ab900fbb 348 Gene3D G3DSA:3.40.50.300 17 241 8.8E-60 T 12-10-2018 TL08_03885 81b0a567af9539351f0986933f3b71d5 255 SUPERFAMILY SSF46785 5 79 7.25E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_03885 81b0a567af9539351f0986933f3b71d5 255 Pfam PF01614 Bacterial transcriptional regulator 124 248 3.5E-32 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_03885 81b0a567af9539351f0986933f3b71d5 255 SMART SM00346 5 96 6.4E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_03885 81b0a567af9539351f0986933f3b71d5 255 Gene3D G3DSA:1.10.10.10 3 80 3.7E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03885 81b0a567af9539351f0986933f3b71d5 255 SUPERFAMILY SSF55781 72 251 2.42E-50 T 12-10-2018 TL08_03885 81b0a567af9539351f0986933f3b71d5 255 Pfam PF09339 IclR helix-turn-helix domain 7 58 7.8E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_03885 81b0a567af9539351f0986933f3b71d5 255 Gene3D G3DSA:3.30.450.40 81 254 3.2E-57 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF52151 572 882 4.45E-71 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF53901 32 406 1.2E-100 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 576 917 1.6E-116 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4281 4613 4.4E-91 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2395 2761 3.9E-110 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:1.10.1200.10 5228 5320 6.3E-30 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:1.10.1200.10 1745 1836 2.0E-32 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 538 4.0E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2230 2357 5.0E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4113 4240 2.2E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF51735 3357 3553 4.82E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.40.366.10 574 920 8.7E-155 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.30.70.3290 488 964 8.7E-155 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF47336 1757 1867 1.31E-25 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF08990 Erythronolide synthase docking 2 26 3.0E-7 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.40.366.10 2393 2764 4.6E-143 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.40.50.720 4676 5211 2.1E-153 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF14765 Polyketide synthase dehydratase 2828 3122 1.5E-47 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF14765 Polyketide synthase dehydratase 983 1253 3.4E-54 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF08659 KR domain 1476 1655 1.5E-58 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF08659 KR domain 3360 3537 5.9E-60 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF08659 KR domain 4962 5138 4.2E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF55048 4404 4485 3.14E-7 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.10.129.110 972 1256 6.5E-105 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.10.129.110 2817 3126 8.8E-91 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1852 2102 2.4E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.4E-89 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3735 3985 1.8E-91 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.40.366.10 4279 4616 5.5E-139 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF53901 3733 4107 1.84E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF51735 1260 1445 1.02E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1789 1804 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF55048 715 784 1.12E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2015 2031 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00826 2828 3001 4.6E-56 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00826 983 1142 3.4E-68 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF51735 3134 3318 5.9E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF00698 Acyl transferase domain 576 934 2.9E-54 T 12-10-2018 IPR014043 Acyl transferase TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF00698 Acyl transferase domain 4279 4632 1.8E-70 T 12-10-2018 IPR014043 Acyl transferase TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF00698 Acyl transferase domain 2395 2710 1.1E-47 T 12-10-2018 IPR014043 Acyl transferase TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.30.70.3290 2307 2809 4.6E-143 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF51735 1475 1688 1.24E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF55048 2533 2614 5.36E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.40.50.720 1262 1738 1.7E-121 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00823 Phosphopantetheine attachment site 1762 1834 9.2E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00823 Phosphopantetheine attachment site 3643 3715 6.7E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00823 Phosphopantetheine attachment site 5245 5317 3.5E-28 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.30.70.3290 4190 4662 5.5E-139 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF53901 1849 2225 9.34E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF51735 4959 5192 1.2E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF51735 4729 4945 2.68E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00825 Beta-ketoacyl synthase 1854 2280 1.1E-227 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00825 Beta-ketoacyl synthase 36 462 7.6E-224 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00825 Beta-ketoacyl synthase 3737 4163 2.1E-228 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3898 3914 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2110 2227 2.1E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3993 4110 1.6E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 4.8E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3670 3685 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF47336 5239 5323 8.64E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF00550 Phosphopantetheine attachment site 5249 5313 4.7E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF00550 Phosphopantetheine attachment site 3649 3711 5.4E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Pfam PF00550 Phosphopantetheine attachment site 1764 1830 5.4E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1476 1657 2.9E-53 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3359 3539 2.8E-49 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4961 5140 1.5E-50 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.40.50.720 3127 3621 2.4E-119 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM01294 1763 1830 9.5E-5 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM01294 3648 3711 8.6E-5 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SMART SM01294 5245 5313 2.1E-6 T 12-10-2018 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.40.47.10 1846 2299 2.4E-189 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.40.47.10 3730 4189 2.4E-189 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:3.40.47.10 25 482 8.4E-188 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 Gene3D G3DSA:1.10.1200.10 3623 3715 3.9E-31 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF52151 4279 4580 5.23E-63 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF52151 2391 2710 2.2E-64 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 SUPERFAMILY SSF47336 3637 3749 9.55E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15930 ae445e6e1c6521d5e6761988005e12e1 5412 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5272 5287 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Gene3D G3DSA:3.40.50.720 1667 1912 6.4E-65 T 12-10-2018 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SMART SM00823 Phosphopantetheine attachment site 1956 2028 2.4E-24 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1378 1433 1.1E-4 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SUPERFAMILY SSF52151 548 829 2.14E-64 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1673 1849 2.1E-49 T 12-10-2018 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Gene3D G3DSA:3.40.50.1820 2048 2318 1.2E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF00550 Phosphopantetheine attachment site 1958 2024 1.3E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SUPERFAMILY SSF51735 1456 1594 2.48E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 413 525 3.1E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF00975 Thioesterase domain 2116 2204 2.6E-11 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Gene3D G3DSA:3.40.47.10 26 475 3.6E-187 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SUPERFAMILY SSF53901 32 408 6.92E-105 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 6.5E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 7.2E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Gene3D G3DSA:1.10.1200.10 1940 2030 9.2E-28 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SUPERFAMILY SSF50129 1373 1485 3.3E-24 T 12-10-2018 IPR011032 GroES-like superfamily TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1983 1998 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Gene3D G3DSA:3.10.129.110 892 1165 2.5E-100 T 12-10-2018 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SUPERFAMILY SSF55048 671 733 8.63E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SMART SM00824 Thioesterase 2103 2316 3.3E-56 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Gene3D G3DSA:3.40.366.10 549 845 5.9E-148 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF13602 Zinc-binding dehydrogenase 1533 1663 5.4E-17 T 12-10-2018 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SMART SM00829 1358 1663 1.2E-160 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Gene3D G3DSA:3.30.70.3290 477 889 5.9E-148 T 12-10-2018 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SUPERFAMILY SSF51735 1168 1336 1.18E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Gene3D G3DSA:3.40.50.11460 1171 1337 2.6E-47 T 12-10-2018 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SUPERFAMILY SSF51735 1671 1877 8.3E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF14765 Polyketide synthase dehydratase 897 1160 2.4E-51 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF00698 Acyl transferase domain 549 858 6.3E-86 T 12-10-2018 IPR014043 Acyl transferase TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SMART SM01294 1961 2024 2.1E-4 T 12-10-2018 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1485 1506 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SUPERFAMILY SSF53474 1986 2318 2.55E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Pfam PF08659 KR domain 1673 1847 1.5E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 Gene3D G3DSA:3.90.180.10 1341 1666 1.6E-117 T 12-10-2018 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SMART SM00825 Beta-ketoacyl synthase 37 463 4.0E-220 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SMART SM00826 897 1055 1.4E-75 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15995 aa0f222b3bd57c926b44c06d07f457e6 2319 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 551 842 1.0E-111 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_24270 3aae92733fb2f3280d105c2a25fd121d 224 SUPERFAMILY SSF53335 21 223 1.42E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_24270 3aae92733fb2f3280d105c2a25fd121d 224 Pfam PF13649 Methyltransferase domain 64 152 7.2E-18 T 12-10-2018 TL08_24270 3aae92733fb2f3280d105c2a25fd121d 224 Gene3D G3DSA:3.40.50.150 17 222 1.3E-49 T 12-10-2018 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 359 42.494 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 Pfam PF06071 Protein of unknown function (DUF933) 275 358 7.1E-38 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 Gene3D G3DSA:3.10.20.30 48 357 1.1E-138 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 Pfam PF01926 50S ribosome-binding GTPase 5 123 1.9E-21 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 Gene3D G3DSA:1.10.150.300 113 198 1.1E-138 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 359 1.0E-131 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 PIRSF PIRSF006641 1 359 2.4E-139 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 4.6E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 4.6E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.6E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 4.6E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 SUPERFAMILY SSF81271 275 359 4.14E-34 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 SUPERFAMILY SSF52540 3 297 1.69E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04240 c216bc530d3d15f68a5d78d25ef26afe 359 Gene3D G3DSA:3.40.50.300 4 274 1.1E-138 T 12-10-2018 TL08_02805 205b1effe3bad0bd4ae7ae0cd6df9d19 313 SMART SM00342 224 307 2.6E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_02805 205b1effe3bad0bd4ae7ae0cd6df9d19 313 Pfam PF12852 Cupin 2 192 2.6E-52 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain TL08_02805 205b1effe3bad0bd4ae7ae0cd6df9d19 313 Gene3D G3DSA:1.10.10.60 210 311 3.5E-23 T 12-10-2018 TL08_02805 205b1effe3bad0bd4ae7ae0cd6df9d19 313 Pfam PF12833 Helix-turn-helix domain 230 307 5.7E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_02805 205b1effe3bad0bd4ae7ae0cd6df9d19 313 SUPERFAMILY SSF46689 260 307 9.96E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_02805 205b1effe3bad0bd4ae7ae0cd6df9d19 313 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 303 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TL08_02805 205b1effe3bad0bd4ae7ae0cd6df9d19 313 SUPERFAMILY SSF46689 207 257 1.05E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_07590 bdeda0ffdd7d85b07d86cd73b2cd95d0 661 SUPERFAMILY SSF51011 572 652 1.51E-24 T 12-10-2018 TL08_07590 bdeda0ffdd7d85b07d86cd73b2cd95d0 661 SUPERFAMILY SSF51445 209 571 1.22E-63 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_07590 bdeda0ffdd7d85b07d86cd73b2cd95d0 661 SUPERFAMILY SSF74650 4 207 3.45E-30 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TL08_07590 bdeda0ffdd7d85b07d86cd73b2cd95d0 661 Gene3D G3DSA:2.60.40.1180 574 652 3.4E-29 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_07590 bdeda0ffdd7d85b07d86cd73b2cd95d0 661 Gene3D G3DSA:3.20.20.80 220 570 1.3E-103 T 12-10-2018 TL08_07590 bdeda0ffdd7d85b07d86cd73b2cd95d0 661 Pfam PF01055 Glycosyl hydrolases family 31 202 655 1.5E-118 T 12-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 TL08_07590 bdeda0ffdd7d85b07d86cd73b2cd95d0 661 Gene3D G3DSA:2.60.40.1760 8 219 2.7E-44 T 12-10-2018 TL08_20010 fd57de321ed83feabaf4dd08d636b763 338 SUPERFAMILY SSF103481 220 323 6.8E-15 T 12-10-2018 TL08_20010 fd57de321ed83feabaf4dd08d636b763 338 Pfam PF00892 EamA-like transporter family 182 318 6.4E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_20010 fd57de321ed83feabaf4dd08d636b763 338 Pfam PF00892 EamA-like transporter family 31 169 1.7E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_20010 fd57de321ed83feabaf4dd08d636b763 338 SUPERFAMILY SSF103481 67 172 7.45E-8 T 12-10-2018 TL08_01200 5127415b4383bf594891459a82aa2570 156 Pfam PF09424 Yqey-like protein 5 154 1.9E-42 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 TL08_01200 5127415b4383bf594891459a82aa2570 156 Gene3D G3DSA:1.10.10.410 94 154 2.7E-13 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TL08_01200 5127415b4383bf594891459a82aa2570 156 Gene3D G3DSA:1.10.1510.10 2 93 1.7E-22 T 12-10-2018 TL08_01200 5127415b4383bf594891459a82aa2570 156 SUPERFAMILY SSF89095 4 154 1.94E-31 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TL08_16115 08ca8b79db648e38134ef71b0e890fe1 361 SUPERFAMILY SSF46894 289 356 3.4E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_16115 08ca8b79db648e38134ef71b0e890fe1 361 SMART SM00421 297 354 5.4E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16115 08ca8b79db648e38134ef71b0e890fe1 361 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 330 342 2.3E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16115 08ca8b79db648e38134ef71b0e890fe1 361 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 300 314 2.3E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16115 08ca8b79db648e38134ef71b0e890fe1 361 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 314 330 2.3E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16115 08ca8b79db648e38134ef71b0e890fe1 361 Gene3D G3DSA:1.10.10.10 237 359 4.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16115 08ca8b79db648e38134ef71b0e890fe1 361 Pfam PF00196 Bacterial regulatory proteins, luxR family 300 354 8.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16115 08ca8b79db648e38134ef71b0e890fe1 361 ProSitePatterns PS00622 LuxR-type HTH domain signature. 314 341 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21835 0dcc3135ca6391887554d6cab46dc6b7 246 Pfam PF02654 Cobalamin-5-phosphate synthase 8 240 1.7E-44 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TL08_21835 0dcc3135ca6391887554d6cab46dc6b7 246 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 246 41.725 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TL08_10790 f45c65fcf97236a41bbd69a6fb0e42b5 484 Pfam PF03471 Transporter associated domain 360 434 6.9E-24 T 12-10-2018 IPR005170 Transporter-associated domain TL08_10790 f45c65fcf97236a41bbd69a6fb0e42b5 484 Pfam PF01595 Domain of unknown function DUF21 13 205 1.4E-31 T 12-10-2018 IPR002550 CNNM, transmembrane domain TL08_10790 f45c65fcf97236a41bbd69a6fb0e42b5 484 SUPERFAMILY SSF54631 212 351 1.1E-24 T 12-10-2018 TL08_10790 f45c65fcf97236a41bbd69a6fb0e42b5 484 SUPERFAMILY SSF56176 356 442 1.96E-23 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_10790 f45c65fcf97236a41bbd69a6fb0e42b5 484 SMART SM01091 358 436 2.6E-26 T 12-10-2018 IPR005170 Transporter-associated domain TL08_10790 f45c65fcf97236a41bbd69a6fb0e42b5 484 Gene3D G3DSA:3.10.580.10 202 351 2.2E-41 T 12-10-2018 TL08_10790 f45c65fcf97236a41bbd69a6fb0e42b5 484 Gene3D G3DSA:3.30.465.10 352 434 6.1E-23 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.30.70.3290 1460 1883 7.1E-162 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.47.10 4378 4810 3.3E-183 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.50.720 5250 5734 1.5E-126 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00823 Phosphopantetheine attachment site 930 1002 1.7E-18 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00823 Phosphopantetheine attachment site 2604 2676 5.3E-28 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00823 Phosphopantetheine attachment site 5763 5835 1.9E-26 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00823 Phosphopantetheine attachment site 4291 4363 1.4E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00698 Acyl transferase domain 4901 5212 1.6E-85 T 12-10-2018 IPR014043 Acyl transferase TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00698 Acyl transferase domain 548 864 7.1E-44 T 12-10-2018 IPR014043 Acyl transferase TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00698 Acyl transferase domain 3221 3539 2.5E-87 T 12-10-2018 IPR014043 Acyl transferase TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00698 Acyl transferase domain 1542 1855 4.5E-62 T 12-10-2018 IPR014043 Acyl transferase TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00826 3588 3748 1.5E-70 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00826 1902 2059 7.0E-71 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF47336 926 1035 6.54E-19 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5790 5805 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF52151 3220 3508 2.88E-65 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:1.10.1200.10 5742 5835 2.8E-29 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:1.10.1200.10 2584 2677 6.8E-30 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.50.720 2173 2572 4.5E-108 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2631 2646 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4318 4333 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.10.129.110 3578 3858 8.1E-92 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.10.129.110 1891 2172 1.7E-99 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1182 1198 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3072 3175 2.6E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1397 1511 5.9E-18 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 377 510 1.7E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4757 4869 2.5E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.30.70.3290 4821 5240 9.3E-155 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF55048 676 740 5.89E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:1.10.1200.10 915 1004 4.2E-20 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:1.10.1200.10 4277 4365 3.3E-31 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00825 Beta-ketoacyl synthase 4384 4807 3.0E-213 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00825 Beta-ketoacyl synthase 10 427 2.6E-189 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00825 Beta-ketoacyl synthase 2696 3122 2.0E-216 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00825 Beta-ketoacyl synthase 1022 1446 8.3E-210 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF51735 5298 5479 1.97E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF55048 1663 1727 6.15E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF55048 5023 5085 1.44E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF47336 2599 2709 1.57E-23 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 258 374 2.0E-36 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2952 3069 1.1E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1277 1394 3.9E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4639 4754 7.5E-46 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF51735 4011 4209 2.23E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF52151 545 830 6.02E-67 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.30.70.3290 3136 3570 2.2E-155 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF52151 4900 5181 1.28E-62 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF55048 3346 3411 5.62E-14 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 ProSitePatterns PS00012 Phosphopantetheine attachment site. 957 972 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4544 4560 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF53901 2690 3066 1.26E-101 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF51735 2324 2531 2.04E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2857 2873 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF53901 6 370 1.48E-88 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.366.10 3221 3525 2.2E-155 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.366.10 1541 1840 7.1E-162 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.366.10 547 850 1.1E-157 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.366.10 4901 5197 9.3E-155 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00550 Phosphopantetheine attachment site 5766 5831 4.2E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00550 Phosphopantetheine attachment site 4298 4359 3.1E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00550 Phosphopantetheine attachment site 2607 2672 9.9E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00550 Phosphopantetheine attachment site 943 998 2.1E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM01294 4292 4359 1.1E-6 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM01294 2605 2672 5.5E-5 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF51735 2125 2312 2.56E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.30.70.3290 465 894 1.1E-157 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.50.720 3859 4275 6.6E-120 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.47.10 1010 1456 2.1E-185 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.47.10 2685 3131 1.8E-184 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Gene3D G3DSA:3.40.47.10 1 437 1.3E-177 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3223 3522 6.5E-119 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4903 5194 6.5E-110 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1543 1837 3.4E-121 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 549 847 8.7E-109 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF51735 5485 5714 1.01E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF53901 1017 1432 1.82E-98 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF53901 4379 4752 2.58E-103 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF47336 4284 4397 1.26E-24 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF14765 Polyketide synthase dehydratase 1902 2168 1.7E-53 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF14765 Polyketide synthase dehydratase 3588 3851 8.7E-51 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF52151 1540 1823 1.31E-73 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2694 2944 8.5E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 250 4.7E-82 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4382 4631 2.5E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1020 1269 7.6E-89 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF08659 KR domain 4014 4195 1.0E-58 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF08659 KR domain 2325 2503 2.7E-58 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 Pfam PF08659 KR domain 5489 5662 2.7E-50 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5489 5664 1.1E-44 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2325 2505 3.4E-58 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4014 4196 1.2E-54 T 12-10-2018 TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF47336 5754 5840 7.59E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15990 9c3caa9eef2dda067e650951cb379005 5914 SUPERFAMILY SSF51735 3860 4002 5.67E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_12935 d43eccf374059cf16c6891ff1bbadb87 257 SUPERFAMILY SSF46955 4 105 5.86E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_12935 d43eccf374059cf16c6891ff1bbadb87 257 Gene3D G3DSA:1.10.1660.10 6 205 5.1E-27 T 12-10-2018 TL08_12935 d43eccf374059cf16c6891ff1bbadb87 257 Pfam PF13411 MerR HTH family regulatory protein 4 69 2.5E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_12935 d43eccf374059cf16c6891ff1bbadb87 257 SMART SM00422 3 72 1.7E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_13200 e28c3e3b87b6708f453eee2d52581c62 368 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 5 288 1.4E-71 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TL08_13200 e28c3e3b87b6708f453eee2d52581c62 368 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 6 282 1.3E-45 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TL08_13200 e28c3e3b87b6708f453eee2d52581c62 368 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 368 69.27 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TL08_13200 e28c3e3b87b6708f453eee2d52581c62 368 SUPERFAMILY SSF55931 2 360 3.83E-81 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TL08_13200 e28c3e3b87b6708f453eee2d52581c62 368 Gene3D G3DSA:3.30.590.20 1 361 2.9E-99 T 12-10-2018 TL08_23115 1406172a22db8b16e87712f9f54f2e6d 380 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_23115 1406172a22db8b16e87712f9f54f2e6d 380 Pfam PF00005 ABC transporter 19 163 1.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23115 1406172a22db8b16e87712f9f54f2e6d 380 SUPERFAMILY SSF52540 1 239 8.68E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23115 1406172a22db8b16e87712f9f54f2e6d 380 Gene3D G3DSA:3.40.50.300 1 246 5.6E-71 T 12-10-2018 TL08_23115 1406172a22db8b16e87712f9f54f2e6d 380 SMART SM00382 27 212 1.2E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 SUPERFAMILY SSF52922 468 586 1.31E-25 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 Gene3D G3DSA:3.40.50.920 466 590 1.3E-29 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 203 245 9.7E-8 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 7 197 1.0E-84 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 ProSitePatterns PS00802 Transketolase signature 2. 387 403 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 SMART SM00861 281 445 2.6E-52 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 Gene3D G3DSA:3.40.50.970 278 450 1.1E-57 T 12-10-2018 TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 Pfam PF02780 Transketolase, C-terminal domain 468 578 9.6E-26 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 Gene3D G3DSA:3.40.50.970 1 254 5.4E-81 T 12-10-2018 TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 SUPERFAMILY SSF52518 257 441 8.13E-54 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 6 587 37.861 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 ProSitePatterns PS00801 Transketolase signature 1. 32 51 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 SUPERFAMILY SSF52518 25 328 1.97E-70 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_18475 f7ff1b2534a8eb76fcc031f6cc6340cd 602 Pfam PF02779 Transketolase, pyrimidine binding domain 281 442 1.0E-37 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_14775 fe7ed301f3c631ddd1d7afa777d8c1c5 219 Gene3D G3DSA:1.20.120.530 75 212 8.1E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_14775 fe7ed301f3c631ddd1d7afa777d8c1c5 219 SMART SM00345 13 71 4.8E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_14775 fe7ed301f3c631ddd1d7afa777d8c1c5 219 SUPERFAMILY SSF48008 78 209 3.14E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_14775 fe7ed301f3c631ddd1d7afa777d8c1c5 219 SUPERFAMILY SSF46785 3 75 2.3E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_14775 fe7ed301f3c631ddd1d7afa777d8c1c5 219 Gene3D G3DSA:1.10.10.10 5 73 9.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_14775 fe7ed301f3c631ddd1d7afa777d8c1c5 219 SMART SM00895 81 205 1.1E-14 T 12-10-2018 IPR011711 GntR, C-terminal TL08_14775 fe7ed301f3c631ddd1d7afa777d8c1c5 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 9.7E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_14775 fe7ed301f3c631ddd1d7afa777d8c1c5 219 Pfam PF07729 FCD domain 81 204 1.7E-21 T 12-10-2018 IPR011711 GntR, C-terminal TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 SUPERFAMILY SSF46946 162 242 4.06E-18 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 SUPERFAMILY SSF57716 251 295 1.71E-11 T 12-10-2018 TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 Gene3D G3DSA:3.20.190.10 25 135 5.6E-14 T 12-10-2018 IPR035937 MutM-like, N-terminal TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 Pfam PF06827 Zinc finger found in FPG and IleRS 267 295 4.4E-7 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 SMART SM00898 25 148 1.1E-22 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 SMART SM01232 162 249 1.6E-23 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 173 242 8.2E-14 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 25 109 5.7E-16 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 Gene3D G3DSA:1.10.8.50 162 295 3.8E-30 T 12-10-2018 TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 ProSitePatterns PS01242 Zinc finger FPG-type signature. 270 294 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 TL08_00355 ade64f1cc92a5f295d419cd695e7e1f9 310 SUPERFAMILY SSF81624 25 165 1.27E-21 T 12-10-2018 IPR035937 MutM-like, N-terminal TL08_03385 92a36efb277ac450fb28cf54d2858014 366 SMART SM00304 86 139 1.2E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_03385 92a36efb277ac450fb28cf54d2858014 366 SUPERFAMILY SSF47384 123 203 1.8E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_03385 92a36efb277ac450fb28cf54d2858014 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 338 5.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03385 92a36efb277ac450fb28cf54d2858014 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 312 5.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03385 92a36efb277ac450fb28cf54d2858014 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 5.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03385 92a36efb277ac450fb28cf54d2858014 366 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 357 5.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03385 92a36efb277ac450fb28cf54d2858014 366 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 250 358 4.1E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_03385 92a36efb277ac450fb28cf54d2858014 366 Gene3D G3DSA:1.10.287.130 90 200 2.0E-22 T 12-10-2018 TL08_03385 92a36efb277ac450fb28cf54d2858014 366 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 202 3.4E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_03385 92a36efb277ac450fb28cf54d2858014 366 SUPERFAMILY SSF158472 88 137 1.29E-6 T 12-10-2018 TL08_03385 92a36efb277ac450fb28cf54d2858014 366 SMART SM00387 246 360 5.8E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_03385 92a36efb277ac450fb28cf54d2858014 366 SUPERFAMILY SSF55874 203 361 6.02E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_03385 92a36efb277ac450fb28cf54d2858014 366 Gene3D G3DSA:3.30.565.10 201 359 2.6E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_03385 92a36efb277ac450fb28cf54d2858014 366 SMART SM00388 140 204 8.5E-5 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_19695 18e097ce61fbc3e406552f3a2747b1ac 238 Pfam PF01925 Sulfite exporter TauE/SafE 10 230 6.1E-18 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 SMART SM00823 Phosphopantetheine attachment site 1009 1077 1.4E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 Gene3D G3DSA:3.30.559.30 215 471 2.3E-123 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 SUPERFAMILY SSF56801 473 1022 2.62E-139 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 Gene3D G3DSA:3.40.50.12780 497 895 9.2E-122 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 SUPERFAMILY SSF52777 33 211 4.78E-39 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 Gene3D G3DSA:3.30.300.30 896 997 7.8E-32 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 Pfam PF00501 AMP-binding enzyme 509 901 1.6E-82 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 SUPERFAMILY SSF47336 1002 1074 1.2E-17 T 12-10-2018 IPR036736 ACP-like superfamily TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 Pfam PF00550 Phosphopantetheine attachment site 1010 1073 3.9E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 Pfam PF00668 Condensation domain 31 482 1.5E-78 T 12-10-2018 IPR001242 Condensation domain TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 Gene3D G3DSA:3.40.50.1820 998 1109 1.2E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 ProSitePatterns PS00455 Putative AMP-binding domain signature. 648 659 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 Gene3D G3DSA:3.30.559.10 33 405 2.3E-123 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 SUPERFAMILY SSF52777 219 470 2.15E-55 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 Pfam PF13193 AMP-binding enzyme C-terminal domain 912 983 1.6E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 530 925 1.1E-117 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 PIRSF PIRSF001617 220 620 2.0E-14 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 PIRSF PIRSF001617 830 869 3.4 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 PIRSF PIRSF001617 615 789 1.7E-11 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 PIRSF PIRSF001617 943 1099 6.3E-20 T 12-10-2018 TL08_05010 1e0662c2ae8b6d9702e7eec86d5c632d 1119 PIRSF PIRSF001617 862 948 8.4E-16 T 12-10-2018 TL08_16280 bf376e4ea7d8246b0996a3218b07c69b 506 Gene3D G3DSA:1.20.1720.10 9 217 5.7E-41 T 12-10-2018 TL08_16280 bf376e4ea7d8246b0996a3218b07c69b 506 SUPERFAMILY SSF103473 3 488 9.42E-63 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_16280 bf376e4ea7d8246b0996a3218b07c69b 506 Pfam PF07690 Major Facilitator Superfamily 15 283 6.3E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_16280 bf376e4ea7d8246b0996a3218b07c69b 506 Pfam PF00083 Sugar (and other) transporter 294 406 5.3E-7 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TL08_16280 bf376e4ea7d8246b0996a3218b07c69b 506 Gene3D G3DSA:1.20.1250.20 262 490 7.0E-19 T 12-10-2018 TL08_16280 bf376e4ea7d8246b0996a3218b07c69b 506 PRINTS PR01036 Tetracycline resistance protein TetB signature 72 94 1.4E-6 T 12-10-2018 TL08_16280 bf376e4ea7d8246b0996a3218b07c69b 506 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 1.4E-6 T 12-10-2018 TL08_16280 bf376e4ea7d8246b0996a3218b07c69b 506 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 1.4E-6 T 12-10-2018 TL08_01940 df81d4694f1985c60f66362645ae2e56 300 SUPERFAMILY SSF161098 24 300 2.71E-69 T 12-10-2018 IPR035906 MetI-like superfamily TL08_01940 df81d4694f1985c60f66362645ae2e56 300 Gene3D G3DSA:1.10.3720.10 21 287 1.1E-60 T 12-10-2018 IPR035906 MetI-like superfamily TL08_01940 df81d4694f1985c60f66362645ae2e56 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 291 1.4E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_11915 8c997690b78bcbe320544589500deefe 241 Pfam PF13580 SIS domain 13 143 1.3E-36 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TL08_11915 8c997690b78bcbe320544589500deefe 241 Gene3D G3DSA:3.40.50.10490 4 233 8.6E-55 T 12-10-2018 TL08_11915 8c997690b78bcbe320544589500deefe 241 SUPERFAMILY SSF53697 16 193 7.34E-18 T 12-10-2018 TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 Pfam PF16193 AAA C-terminal domain 211 287 8.6E-27 T 12-10-2018 IPR032423 AAA C-terminal domain TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 76 180 6.2E-16 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 Gene3D G3DSA:1.20.272.10 261 365 1.1E-47 T 12-10-2018 TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 Gene3D G3DSA:1.10.3710.10 366 464 2.5E-23 T 12-10-2018 TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 SUPERFAMILY SSF52540 38 255 6.74E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 SMART SM00382 72 188 1.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 Pfam PF12002 MgsA AAA+ ATPase C terminal 288 453 8.0E-70 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 Gene3D G3DSA:1.10.8.60 189 259 6.9E-11 T 12-10-2018 TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 Gene3D G3DSA:3.40.50.300 28 188 4.7E-38 T 12-10-2018 TL08_11320 4813299cc06fcc8b581d2fc44e66ac2c 465 SUPERFAMILY SSF48019 273 456 1.15E-73 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TL08_03530 78f04c04021e8054029441480f725f45 593 Pfam PF09334 tRNA synthetases class I (M) 2 407 1.3E-143 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_03530 78f04c04021e8054029441480f725f45 593 Gene3D G3DSA:2.20.28.20 136 170 5.6E-144 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_03530 78f04c04021e8054029441480f725f45 593 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 542 6.5E-147 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TL08_03530 78f04c04021e8054029441480f725f45 593 Gene3D G3DSA:3.40.50.620 2 390 5.6E-144 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_03530 78f04c04021e8054029441480f725f45 593 SUPERFAMILY SSF47323 396 577 4.49E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_03530 78f04c04021e8054029441480f725f45 593 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 588 37.318 T 12-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_03530 78f04c04021e8054029441480f725f45 593 SUPERFAMILY SSF52374 4 395 5.63E-92 T 12-10-2018 TL08_03530 78f04c04021e8054029441480f725f45 593 Gene3D G3DSA:1.10.730.10 391 584 2.6E-36 T 12-10-2018 TL08_03530 78f04c04021e8054029441480f725f45 593 PRINTS PR01041 Methionyl-tRNA synthetase signature 249 260 1.5E-24 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TL08_03530 78f04c04021e8054029441480f725f45 593 PRINTS PR01041 Methionyl-tRNA synthetase signature 84 95 1.5E-24 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TL08_03530 78f04c04021e8054029441480f725f45 593 PRINTS PR01041 Methionyl-tRNA synthetase signature 289 304 1.5E-24 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TL08_03530 78f04c04021e8054029441480f725f45 593 PRINTS PR01041 Methionyl-tRNA synthetase signature 36 50 1.5E-24 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TL08_03530 78f04c04021e8054029441480f725f45 593 PRINTS PR01041 Methionyl-tRNA synthetase signature 3 16 1.5E-24 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TL08_03530 78f04c04021e8054029441480f725f45 593 PRINTS PR01041 Methionyl-tRNA synthetase signature 395 406 1.5E-24 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TL08_03530 78f04c04021e8054029441480f725f45 593 SUPERFAMILY SSF57770 136 169 5.1E-11 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_01105 5e6cc26818faf53fd7c7b41e9554f057 392 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 258 347 1.0E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_01105 5e6cc26818faf53fd7c7b41e9554f057 392 ProSitePatterns PS00211 ABC transporters family signature. 180 194 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_01105 5e6cc26818faf53fd7c7b41e9554f057 392 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 259 325 2.9E-15 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_01105 5e6cc26818faf53fd7c7b41e9554f057 392 Gene3D G3DSA:3.40.50.300 25 363 5.4E-102 T 12-10-2018 TL08_01105 5e6cc26818faf53fd7c7b41e9554f057 392 SUPERFAMILY SSF52540 28 279 4.55E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01105 5e6cc26818faf53fd7c7b41e9554f057 392 SMART SM00382 64 257 7.7E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01105 5e6cc26818faf53fd7c7b41e9554f057 392 Pfam PF00005 ABC transporter 56 207 2.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05120 da0c532f17baa0f8c14d125cbe9e11d7 109 SUPERFAMILY SSF46785 1 94 1.07E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05120 da0c532f17baa0f8c14d125cbe9e11d7 109 Gene3D G3DSA:1.10.10.10 1 102 2.7E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05120 da0c532f17baa0f8c14d125cbe9e11d7 109 SMART SM00418 3 81 6.5E-24 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_05120 da0c532f17baa0f8c14d125cbe9e11d7 109 Pfam PF01022 Bacterial regulatory protein, arsR family 11 55 2.1E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_05120 da0c532f17baa0f8c14d125cbe9e11d7 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.1E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_05120 da0c532f17baa0f8c14d125cbe9e11d7 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.1E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_05120 da0c532f17baa0f8c14d125cbe9e11d7 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.1E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 Gene3D G3DSA:3.50.50.60 48 410 2.0E-129 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 361 367 3.4E-33 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 391 403 3.4E-33 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 60 70 3.4E-33 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 47 59 3.4E-33 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 76 88 3.4E-33 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 122 134 3.4E-33 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 SUPERFAMILY SSF51905 38 276 2.87E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 52 69 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 424 549 4.8E-34 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 Gene3D G3DSA:1.10.8.870 435 578 2.9E-33 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 Pfam PF01266 FAD dependent oxidoreductase 48 396 5.9E-53 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 Gene3D G3DSA:3.30.9.10 126 368 2.0E-129 T 12-10-2018 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 SUPERFAMILY SSF54373 275 367 2.16E-6 T 12-10-2018 TL08_23795 6a209df06485be9158c7cf38b68e15f7 596 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 396 406 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TL08_08250 7377fa959f90035e8bdfb6b4aaa8cc1f 274 SUPERFAMILY SSF47781 203 273 6.0E-26 T 12-10-2018 IPR010994 RuvA domain 2-like TL08_08250 7377fa959f90035e8bdfb6b4aaa8cc1f 274 SMART SM00278 252 271 3.8 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TL08_08250 7377fa959f90035e8bdfb6b4aaa8cc1f 274 SMART SM00278 222 241 0.0049 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TL08_08250 7377fa959f90035e8bdfb6b4aaa8cc1f 274 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 210 273 3.1E-15 T 12-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain TL08_08250 7377fa959f90035e8bdfb6b4aaa8cc1f 274 Pfam PF12836 Helix-hairpin-helix motif 213 273 3.5E-21 T 12-10-2018 TL08_08250 7377fa959f90035e8bdfb6b4aaa8cc1f 274 Gene3D G3DSA:1.10.150.320 198 273 2.3E-22 T 12-10-2018 TL08_08250 7377fa959f90035e8bdfb6b4aaa8cc1f 274 Gene3D G3DSA:3.10.560.10 119 189 7.9E-10 T 12-10-2018 TL08_08250 7377fa959f90035e8bdfb6b4aaa8cc1f 274 Pfam PF10531 SLBB domain 130 184 9.8E-12 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 Gene3D G3DSA:3.30.70.270 251 430 5.4E-37 T 12-10-2018 TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 SUPERFAMILY SSF55785 119 243 5.72E-21 T 12-10-2018 IPR035965 PAS domain superfamily TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 SMART SM00267 245 417 9.8E-31 T 12-10-2018 IPR000160 GGDEF domain TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 Pfam PF00990 Diguanylate cyclase, GGDEF domain 257 412 2.7E-29 T 12-10-2018 IPR000160 GGDEF domain TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 Gene3D G3DSA:3.30.450.20 116 243 3.9E-19 T 12-10-2018 TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 SUPERFAMILY SSF141868 436 682 4.97E-37 T 12-10-2018 IPR035919 EAL domain superfamily TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 126 251 6.0E-18 T 12-10-2018 IPR000014 PAS domain TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 Pfam PF13426 PAS domain 147 244 2.5E-10 T 12-10-2018 IPR000014 PAS domain TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 SMART SM00091 130 196 2.2E-9 T 12-10-2018 IPR000014 PAS domain TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 SMART SM00052 427 674 1.9E-12 T 12-10-2018 IPR001633 EAL domain TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 SUPERFAMILY SSF55073 261 419 1.8E-31 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 Pfam PF00563 EAL domain 436 670 8.3E-36 T 12-10-2018 IPR001633 EAL domain TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 254 415 2.3E-24 T 12-10-2018 IPR000160 GGDEF domain TL08_06415 9c169825bb19f7e436405cff7b2b5a36 685 Gene3D G3DSA:3.20.20.450 431 684 1.0E-47 T 12-10-2018 IPR035919 EAL domain superfamily TL08_15515 66ecc79a6fb285f833bbe10091f549bc 273 SMART SM00530 13 68 9.3E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_15515 66ecc79a6fb285f833bbe10091f549bc 273 SUPERFAMILY SSF47413 7 67 1.04E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_15515 66ecc79a6fb285f833bbe10091f549bc 273 Gene3D G3DSA:1.10.260.40 6 78 1.4E-13 T 12-10-2018 TL08_15515 66ecc79a6fb285f833bbe10091f549bc 273 Pfam PF13560 Helix-turn-helix domain 10 69 5.0E-13 T 12-10-2018 TL08_23560 58d28b97752a503674a24664fb2dccfc 224 SUPERFAMILY SSF52172 4 122 6.12E-41 T 12-10-2018 IPR011006 CheY-like superfamily TL08_23560 58d28b97752a503674a24664fb2dccfc 224 SMART SM00448 2 113 1.1E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_23560 58d28b97752a503674a24664fb2dccfc 224 SMART SM00862 143 221 4.2E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_23560 58d28b97752a503674a24664fb2dccfc 224 Gene3D G3DSA:1.10.10.10 121 224 3.8E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23560 58d28b97752a503674a24664fb2dccfc 224 SUPERFAMILY SSF46894 124 223 9.07E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_23560 58d28b97752a503674a24664fb2dccfc 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 221 9.3E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_23560 58d28b97752a503674a24664fb2dccfc 224 Gene3D G3DSA:3.40.50.2300 1 120 3.0E-37 T 12-10-2018 TL08_23560 58d28b97752a503674a24664fb2dccfc 224 Pfam PF00072 Response regulator receiver domain 4 114 1.8E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_10500 9cc49c5860fd0d6eed2574d6f046ff44 206 SUPERFAMILY SSF46785 10 186 1.72E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_10500 9cc49c5860fd0d6eed2574d6f046ff44 206 Gene3D G3DSA:1.10.10.10 2 105 1.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_10500 9cc49c5860fd0d6eed2574d6f046ff44 206 Pfam PF03551 Transcriptional regulator PadR-like family 14 89 5.5E-12 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 SUPERFAMILY SSF55874 370 537 6.16E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 Pfam PF00672 HAMP domain 266 314 1.4E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 SMART SM00304 265 317 4.1E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 SMART SM00388 318 381 9.5E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 SUPERFAMILY SSF47384 301 381 1.71E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 SUPERFAMILY SSF158472 267 314 1.96E-7 T 12-10-2018 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 530 5.4E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 487 1.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 1.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 529 1.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 1.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 Gene3D G3DSA:3.30.565.10 411 537 7.9E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 Pfam PF00512 His Kinase A (phospho-acceptor) domain 319 380 6.1E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 Gene3D G3DSA:1.10.287.130 269 382 1.3E-31 T 12-10-2018 TL08_18330 dfb54dc9d48865bdfbf1922cc28c2f0d 548 SMART SM00387 422 532 2.7E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.30.70.3290 1902 2279 1.9E-121 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:1.10.1200.10 2783 2877 2.6E-31 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:1.10.1200.10 4243 4335 8.3E-30 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:1.10.1200.10 1362 1455 8.7E-33 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.30.70.3290 471 848 4.7E-119 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF51735 3805 3963 2.44E-16 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF52151 3402 3690 1.2E-60 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF51735 3972 4235 2.91E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF51735 908 1087 3.62E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF55048 2077 2134 3.4E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF08659 KR domain 1101 1278 7.1E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF08659 KR domain 3976 4154 2.0E-51 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF08659 KR domain 2526 2699 5.0E-48 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00823 Phosphopantetheine attachment site 1382 1454 3.9E-31 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00823 Phosphopantetheine attachment site 2804 2876 1.5E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00823 Phosphopantetheine attachment site 4263 4335 2.8E-28 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4290 4305 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF47336 2799 2910 1.7E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF47336 4257 4334 8.24E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF55048 3526 3591 2.62E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF52151 1967 2225 9.94E-61 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF00550 Phosphopantetheine attachment site 2808 2872 2.2E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF00550 Phosphopantetheine attachment site 1384 1450 3.7E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF00550 Phosphopantetheine attachment site 4265 4331 4.6E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF51735 1097 1329 6.97E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2526 2701 8.6E-46 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1101 1280 3.8E-50 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3976 4156 1.8E-45 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF53901 38 402 5.03E-97 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF51735 2338 2515 2.24E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF55048 646 703 3.92E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2831 2846 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 539 805 3.9E-91 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1970 2236 1.1E-92 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3406 3700 1.6E-106 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF53901 2893 3251 1.85E-94 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1721 1836 6.3E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3140 3253 2.5E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 404 9.2E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3045 3061 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.30.70.3290 3322 3746 1.3E-145 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM01294 1383 1450 1.0E-6 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM01294 2805 2872 8.4E-4 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM01294 4264 4331 1.8E-6 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF53901 1469 1834 1.58E-100 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.40.50.720 3760 4230 1.8E-127 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.40.50.720 2292 2773 1.4E-136 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF47336 1378 1488 1.44E-25 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.40.50.720 861 1352 3.1E-135 T 12-10-2018 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF51735 2522 2733 3.21E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1839 1952 1.2E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3258 3366 7.1E-11 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 407 521 4.0E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.40.366.10 3404 3703 1.3E-145 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.40.366.10 537 805 4.7E-119 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.40.366.10 1968 2237 1.9E-121 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1626 1642 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1409 1424 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF00698 Acyl transferase domain 539 786 1.9E-43 T 12-10-2018 IPR014043 Acyl transferase TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF00698 Acyl transferase domain 3404 3719 6.9E-82 T 12-10-2018 IPR014043 Acyl transferase TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF00698 Acyl transferase domain 1971 2240 6.3E-44 T 12-10-2018 IPR014043 Acyl transferase TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.40.47.10 1461 1890 3.2E-180 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.40.47.10 23 458 1.6E-176 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Gene3D G3DSA:3.40.47.10 2883 3307 1.1E-173 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SUPERFAMILY SSF52151 536 799 8.89E-61 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 194 210 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00825 Beta-ketoacyl synthase 2897 3308 3.9E-198 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00825 Beta-ketoacyl synthase 43 457 1.0E-197 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 SMART SM00825 Beta-ketoacyl synthase 1475 1889 4.7E-205 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1473 1713 1.6E-80 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 41 281 8.6E-75 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14585 e1ea8b93a840cfc9e0cb762d3f6e6658 4412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2895 3132 2.0E-80 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_24140 0c92864caa90531fd63cc4c058f3d7c4 270 Gene3D G3DSA:1.10.10.10 1 99 5.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_24140 0c92864caa90531fd63cc4c058f3d7c4 270 SMART SM01043 103 248 5.0E-44 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_24140 0c92864caa90531fd63cc4c058f3d7c4 270 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 83 3.4E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_24140 0c92864caa90531fd63cc4c058f3d7c4 270 Gene3D G3DSA:1.25.40.10 101 269 6.2E-42 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_24140 0c92864caa90531fd63cc4c058f3d7c4 270 SUPERFAMILY SSF48452 98 265 1.66E-36 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_24140 0c92864caa90531fd63cc4c058f3d7c4 270 SMART SM00862 17 96 6.3E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_24140 0c92864caa90531fd63cc4c058f3d7c4 270 SUPERFAMILY SSF46894 3 80 1.45E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_24140 0c92864caa90531fd63cc4c058f3d7c4 270 Pfam PF03704 Bacterial transcriptional activator domain 103 248 5.3E-40 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_20875 971b049716ff4f25373be34b9f25fec6 391 Gene3D G3DSA:1.10.260.40 17 90 7.2E-16 T 12-10-2018 TL08_20875 971b049716ff4f25373be34b9f25fec6 391 SMART SM00530 29 84 3.7E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_20875 971b049716ff4f25373be34b9f25fec6 391 Pfam PF06114 IrrE N-terminal-like domain 172 286 1.1E-20 T 12-10-2018 IPR010359 IrrE N-terminal-like domain TL08_20875 971b049716ff4f25373be34b9f25fec6 391 Pfam PF13560 Helix-turn-helix domain 32 81 4.8E-12 T 12-10-2018 TL08_20875 971b049716ff4f25373be34b9f25fec6 391 SUPERFAMILY SSF47413 23 88 1.66E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_05955 d4db33d4c77b851acbc6af017af93a79 86 Pfam PF00196 Bacterial regulatory proteins, luxR family 9 61 3.2E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05955 d4db33d4c77b851acbc6af017af93a79 86 Gene3D G3DSA:1.10.10.10 3 67 4.0E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05955 d4db33d4c77b851acbc6af017af93a79 86 SUPERFAMILY SSF46894 7 68 2.62E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_05955 d4db33d4c77b851acbc6af017af93a79 86 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 23 39 4.8E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05955 d4db33d4c77b851acbc6af017af93a79 86 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 39 51 4.8E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05955 d4db33d4c77b851acbc6af017af93a79 86 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 9 23 4.8E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05955 d4db33d4c77b851acbc6af017af93a79 86 SMART SM00421 6 63 4.9E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_22655 816c1ad5c37c7febedb057ef4049d29f 233 Pfam PF09339 IclR helix-turn-helix domain 10 56 3.0E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_22655 816c1ad5c37c7febedb057ef4049d29f 233 Gene3D G3DSA:3.30.450.40 72 232 7.9E-37 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_22655 816c1ad5c37c7febedb057ef4049d29f 233 SUPERFAMILY SSF55781 63 233 1.37E-35 T 12-10-2018 TL08_22655 816c1ad5c37c7febedb057ef4049d29f 233 Gene3D G3DSA:1.10.10.10 2 71 6.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22655 816c1ad5c37c7febedb057ef4049d29f 233 SMART SM00346 7 92 2.0E-21 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_22655 816c1ad5c37c7febedb057ef4049d29f 233 Pfam PF01614 Bacterial transcriptional regulator 124 230 1.1E-14 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_22655 816c1ad5c37c7febedb057ef4049d29f 233 SUPERFAMILY SSF46785 8 74 8.03E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_09615 3e992dd99fdc899a5da922486c9f9f77 242 PIRSF PIRSF006755 1 208 1.1E-34 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 TL08_09615 3e992dd99fdc899a5da922486c9f9f77 242 Pfam PF13500 AAA domain 4 201 2.6E-34 T 12-10-2018 TL08_09615 3e992dd99fdc899a5da922486c9f9f77 242 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 203 23.714 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 TL08_09615 3e992dd99fdc899a5da922486c9f9f77 242 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 169 7.2E-29 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 TL08_09615 3e992dd99fdc899a5da922486c9f9f77 242 SUPERFAMILY SSF52540 1 202 5.05E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09615 3e992dd99fdc899a5da922486c9f9f77 242 Gene3D G3DSA:3.40.50.300 2 224 1.1E-57 T 12-10-2018 TL08_22505 60c517e8453584a73958d98add4b1c7b 345 Gene3D G3DSA:3.40.190.10 147 272 2.7E-64 T 12-10-2018 TL08_22505 60c517e8453584a73958d98add4b1c7b 345 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 74 343 6.1E-27 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TL08_22505 60c517e8453584a73958d98add4b1c7b 345 SUPERFAMILY SSF53850 133 252 7.33E-7 T 12-10-2018 TL08_22505 60c517e8453584a73958d98add4b1c7b 345 Gene3D G3DSA:3.40.190.150 54 336 2.7E-64 T 12-10-2018 TL08_22505 60c517e8453584a73958d98add4b1c7b 345 PIRSF PIRSF017082 15 345 2.6E-84 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 SUPERFAMILY SSF46785 2 62 3.12E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 Gene3D G3DSA:1.10.60.10 74 140 7.4E-30 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 SMART SM00529 26 125 1.4E-41 T 12-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 Gene3D G3DSA:1.10.10.10 1 72 2.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 2.8E-28 T 12-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 SUPERFAMILY SSF50037 130 228 4.17E-19 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 Pfam PF04023 FeoA domain 161 229 1.0E-5 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 Gene3D G3DSA:2.30.30.90 151 229 3.8E-11 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 SUPERFAMILY SSF47979 65 137 1.44E-25 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TL08_08670 05e9c6636fcf0b381823dbabf42b526c 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 5.0E-20 T 12-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 TL08_20310 7efff2a34f0fb7006a7927614ad81cf7 106 Gene3D G3DSA:3.30.750.24 4 103 1.2E-26 T 12-10-2018 IPR036513 STAS domain superfamily TL08_20310 7efff2a34f0fb7006a7927614ad81cf7 106 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 4 99 1.6E-23 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 TL08_20310 7efff2a34f0fb7006a7927614ad81cf7 106 SUPERFAMILY SSF52091 10 100 6.67E-21 T 12-10-2018 IPR036513 STAS domain superfamily TL08_20310 7efff2a34f0fb7006a7927614ad81cf7 106 Pfam PF13466 STAS domain 14 95 1.5E-18 T 12-10-2018 IPR002645 STAS domain TL08_06000 8da0a1035dcf94e19e0f6b5a1933cb40 641 Gene3D G3DSA:3.30.2010.10 73 164 4.8E-5 T 12-10-2018 TL08_06000 8da0a1035dcf94e19e0f6b5a1933cb40 641 Pfam PF01435 Peptidase family M48 77 304 1.2E-13 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TL08_05195 d7110762556dbed2ebbe55a33457da64 401 Gene3D G3DSA:1.20.1250.20 9 389 4.6E-53 T 12-10-2018 TL08_05195 d7110762556dbed2ebbe55a33457da64 401 SUPERFAMILY SSF103473 6 390 7.19E-61 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_05195 d7110762556dbed2ebbe55a33457da64 401 Pfam PF07690 Major Facilitator Superfamily 19 331 5.9E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_08770 5489c4be29286803c30fffb5631c2844 183 Gene3D G3DSA:2.40.30.60 9 98 3.1E-21 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 TL08_08770 5489c4be29286803c30fffb5631c2844 183 SUPERFAMILY SSF50346 106 176 1.7E-15 T 12-10-2018 IPR011033 PRC-barrel-like superfamily TL08_08770 5489c4be29286803c30fffb5631c2844 183 Gene3D G3DSA:2.30.30.240 102 182 2.3E-13 T 12-10-2018 TL08_08770 5489c4be29286803c30fffb5631c2844 183 Pfam PF05239 PRC-barrel domain 104 176 2.3E-10 T 12-10-2018 IPR027275 PRC-barrel domain TL08_08770 5489c4be29286803c30fffb5631c2844 183 SUPERFAMILY SSF50447 9 99 6.36E-17 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_08770 5489c4be29286803c30fffb5631c2844 183 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 11 176 1.3E-37 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TL08_08770 5489c4be29286803c30fffb5631c2844 183 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 10 176 23.713 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TL08_08770 5489c4be29286803c30fffb5631c2844 183 Pfam PF01782 RimM N-terminal domain 13 95 3.0E-19 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 TL08_16545 b8af115e0f219d7325ef183dcf87b363 175 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 28 146 5.1E-12 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TL08_16545 b8af115e0f219d7325ef183dcf87b363 175 SUPERFAMILY SSF55961 12 153 1.14E-28 T 12-10-2018 TL08_16545 b8af115e0f219d7325ef183dcf87b363 175 Gene3D G3DSA:3.30.530.20 4 173 5.1E-32 T 12-10-2018 IPR023393 START-like domain superfamily TL08_24815 5f05340406e35e5260c4949fc35e3d3d 542 Pfam PF09423 PhoD-like phosphatase 177 511 1.0E-110 T 12-10-2018 IPR018946 Alkaline phosphatase D-related TL08_24815 5f05340406e35e5260c4949fc35e3d3d 542 Gene3D G3DSA:2.60.40.380 58 167 8.5E-37 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 TL08_24815 5f05340406e35e5260c4949fc35e3d3d 542 SUPERFAMILY SSF56300 177 515 1.25E-32 T 12-10-2018 TL08_24815 5f05340406e35e5260c4949fc35e3d3d 542 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 66 164 5.3E-32 T 12-10-2018 IPR032093 Phospholipase D, N-terminal TL08_24815 5f05340406e35e5260c4949fc35e3d3d 542 Gene3D G3DSA:3.60.21.70 174 542 1.6E-141 T 12-10-2018 IPR038607 PhoD-like superfamily TL08_02615 651cf89f854837e3dae3132861854bd1 257 SUPERFAMILY SSF143243 101 253 2.09E-49 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02615 651cf89f854837e3dae3132861854bd1 257 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 115 236 4.3E-44 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02615 651cf89f854837e3dae3132861854bd1 257 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 165 226 1.0E-19 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02615 651cf89f854837e3dae3132861854bd1 257 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 116 237 7.1E-45 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02615 651cf89f854837e3dae3132861854bd1 257 Gene3D G3DSA:3.30.460.80 68 217 1.7E-48 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02615 651cf89f854837e3dae3132861854bd1 257 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 85 245 29.571 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_13060 c151f4d8c8b701212c89e4840e051398 288 Gene3D G3DSA:3.30.1360.130 131 271 6.4E-83 T 12-10-2018 TL08_13060 c151f4d8c8b701212c89e4840e051398 288 Pfam PF04951 D-aminopeptidase 14 273 3.4E-91 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TL08_13060 c151f4d8c8b701212c89e4840e051398 288 PIRSF PIRSF015853 14 285 8.1E-89 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TL08_13060 c151f4d8c8b701212c89e4840e051398 288 SUPERFAMILY SSF63992 14 279 2.35E-81 T 12-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily TL08_13060 c151f4d8c8b701212c89e4840e051398 288 Gene3D G3DSA:3.40.50.10780 14 226 6.4E-83 T 12-10-2018 IPR027476 D-aminopeptidase, N-terminal TL08_00270 c384751e758b8b11dc44dd89fea4b2c5 330 SUPERFAMILY SSF53850 52 325 2.77E-60 T 12-10-2018 TL08_00270 c384751e758b8b11dc44dd89fea4b2c5 330 Gene3D G3DSA:3.40.190.10 54 320 3.5E-94 T 12-10-2018 TL08_00270 c384751e758b8b11dc44dd89fea4b2c5 330 Gene3D G3DSA:3.40.190.120 154 264 3.5E-94 T 12-10-2018 TL08_00270 c384751e758b8b11dc44dd89fea4b2c5 330 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 53 321 8.3E-59 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 301 2.5E-21 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 305 38.956 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 1.2E-16 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 1.2E-16 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 1.2E-16 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 1.2E-16 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 303 1.5E-88 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 Gene3D G3DSA:3.40.50.1370 136 282 1.2E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 Gene3D G3DSA:3.40.50.1370 5 298 1.2E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 2.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 2.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 2.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 2.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 2.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 2.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 149 5.9E-41 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 SUPERFAMILY SSF53671 1 304 1.7E-93 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TL08_11480 97f4ada9d011b7a7836c9906db009fca 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_12465 116a00a0c69873ac590f5c7d9638e166 381 Gene3D G3DSA:3.30.390.10 11 373 1.8E-135 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_12465 116a00a0c69873ac590f5c7d9638e166 381 Gene3D G3DSA:3.20.20.120 102 343 1.8E-135 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_12465 116a00a0c69873ac590f5c7d9638e166 381 SMART SM00922 125 230 1.0E-16 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_12465 116a00a0c69873ac590f5c7d9638e166 381 SUPERFAMILY SSF54826 1 112 6.43E-32 T 12-10-2018 TL08_12465 116a00a0c69873ac590f5c7d9638e166 381 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TL08_12465 116a00a0c69873ac590f5c7d9638e166 381 SUPERFAMILY SSF51604 95 358 5.3E-71 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_12465 116a00a0c69873ac590f5c7d9638e166 381 Pfam PF13378 Enolase C-terminal domain-like 129 354 2.5E-55 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_12465 116a00a0c69873ac590f5c7d9638e166 381 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TL08_12465 116a00a0c69873ac590f5c7d9638e166 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 107 3.2E-24 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TL08_21670 a51cccb2461b9ec9cd6f10a5fcfe1b11 256 SUPERFAMILY SSF53474 18 247 2.79E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21670 a51cccb2461b9ec9cd6f10a5fcfe1b11 256 Gene3D G3DSA:3.40.50.1820 2 246 1.3E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21670 a51cccb2461b9ec9cd6f10a5fcfe1b11 256 PIRSF PIRSF017388 3 249 8.3E-59 T 12-10-2018 IPR012354 Esterase/lipase GO:0052689 TL08_21670 a51cccb2461b9ec9cd6f10a5fcfe1b11 256 Pfam PF12146 Serine aminopeptidase, S33 20 225 2.1E-18 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 TL08_10700 7ed8a2532ba86eba565e563ce6755aa4 209 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 2.8E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_10700 7ed8a2532ba86eba565e563ce6755aa4 209 SUPERFAMILY SSF56281 11 201 3.5E-45 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_10700 7ed8a2532ba86eba565e563ce6755aa4 209 SMART SM00849 24 188 2.9E-37 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_10700 7ed8a2532ba86eba565e563ce6755aa4 209 Gene3D G3DSA:3.60.15.10 19 206 5.5E-50 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 Gene3D G3DSA:2.60.40.10 722 835 5.1E-28 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 373 718 1.1E-60 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 PRINTS PR00133 Glycosyl hydrolase family 3 signature 80 99 6.3E-7 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 PRINTS PR00133 Glycosyl hydrolase family 3 signature 169 185 6.3E-7 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 SMART SM01217 755 825 1.9E-25 T 12-10-2018 IPR026891 Fibronectin type III-like domain TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 SUPERFAMILY SSF52279 373 721 3.92E-49 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 65 320 1.7E-37 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 Gene3D G3DSA:2.60.120.260 844 992 1.1E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 SUPERFAMILY SSF49785 846 943 2.76E-6 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 Gene3D G3DSA:3.20.20.300 33 721 5.8E-197 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 Gene3D G3DSA:3.40.50.1700 366 685 5.8E-197 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 SUPERFAMILY SSF50405 475 566 8.5E-9 T 12-10-2018 IPR008999 Actin-crosslinking TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 Pfam PF14310 Fibronectin type III-like domain 755 825 1.5E-18 T 12-10-2018 IPR026891 Fibronectin type III-like domain TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 SUPERFAMILY SSF51445 17 372 7.05E-70 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_07580 e4d4e9c33c215e6061ebd62f54822eec 1000 Gene3D G3DSA:2.60.120.380 450 577 5.8E-197 T 12-10-2018 TL08_00605 9d2e0656ef51b423b88a1f1803d219ff 329 Gene3D G3DSA:3.30.70.260 204 299 1.4E-30 T 12-10-2018 TL08_00605 9d2e0656ef51b423b88a1f1803d219ff 329 SUPERFAMILY SSF53850 3 205 2.55E-39 T 12-10-2018 TL08_00605 9d2e0656ef51b423b88a1f1803d219ff 329 Pfam PF00800 Prephenate dehydratase 4 199 3.1E-37 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TL08_00605 9d2e0656ef51b423b88a1f1803d219ff 329 SUPERFAMILY SSF55021 202 293 4.96E-24 T 12-10-2018 TL08_00605 9d2e0656ef51b423b88a1f1803d219ff 329 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 241 248 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TL08_00605 9d2e0656ef51b423b88a1f1803d219ff 329 Pfam PF01842 ACT domain 215 279 7.7E-11 T 12-10-2018 IPR002912 ACT domain TL08_00605 9d2e0656ef51b423b88a1f1803d219ff 329 PIRSF PIRSF001500 1 295 1.1E-53 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TL08_00605 9d2e0656ef51b423b88a1f1803d219ff 329 Gene3D G3DSA:3.40.190.10 111 191 3.9E-23 T 12-10-2018 TL08_00605 9d2e0656ef51b423b88a1f1803d219ff 329 Gene3D G3DSA:3.40.190.10 1 110 5.5E-20 T 12-10-2018 TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 8.5E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 8.5E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 8.5E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 SUPERFAMILY SSF53474 12 285 1.47E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 PRINTS PR00412 Epoxide hydrolase signature 115 128 3.7E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 PRINTS PR00412 Epoxide hydrolase signature 261 283 3.7E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 PRINTS PR00412 Epoxide hydrolase signature 38 56 3.7E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 PRINTS PR00412 Epoxide hydrolase signature 228 244 3.7E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 Gene3D G3DSA:3.40.50.1820 14 286 1.7E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21005 92a6f15eeefc8fa14d85e75ede22ef86 292 Pfam PF00561 alpha/beta hydrolase fold 32 269 1.9E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_19310 1eae30acdb4e14f9301da1474ec9c3c5 253 SUPERFAMILY SSF100950 74 234 2.3E-29 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_19310 1eae30acdb4e14f9301da1474ec9c3c5 253 Pfam PF00455 DeoR C terminal sensor domain 75 232 3.9E-50 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain TL08_19310 1eae30acdb4e14f9301da1474ec9c3c5 253 SMART SM00420 6 58 6.2E-12 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_19310 1eae30acdb4e14f9301da1474ec9c3c5 253 SUPERFAMILY SSF46785 5 60 1.12E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_19310 1eae30acdb4e14f9301da1474ec9c3c5 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 8.2E-13 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_19310 1eae30acdb4e14f9301da1474ec9c3c5 253 SMART SM01134 73 234 8.6E-70 T 12-10-2018 TL08_19310 1eae30acdb4e14f9301da1474ec9c3c5 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.3E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_19310 1eae30acdb4e14f9301da1474ec9c3c5 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.3E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_17075 233600a53cafccfdf4faa0a58d4369b7 496 Gene3D G3DSA:3.30.200.20 2 95 3.1E-28 T 12-10-2018 TL08_17075 233600a53cafccfdf4faa0a58d4369b7 496 Pfam PF00069 Protein kinase domain 12 264 4.8E-49 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_17075 233600a53cafccfdf4faa0a58d4369b7 496 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_17075 233600a53cafccfdf4faa0a58d4369b7 496 Gene3D G3DSA:1.10.510.10 98 277 1.3E-44 T 12-10-2018 TL08_17075 233600a53cafccfdf4faa0a58d4369b7 496 SMART SM00220 12 272 2.9E-64 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_17075 233600a53cafccfdf4faa0a58d4369b7 496 SUPERFAMILY SSF56112 4 268 2.83E-72 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_17075 233600a53cafccfdf4faa0a58d4369b7 496 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 5.3E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 5.3E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 5.3E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 5.3E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 302 1.2E-51 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 SUPERFAMILY SSF53671 2 305 2.36E-99 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 305 77.392 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 Gene3D G3DSA:3.40.50.1370 9 300 4.2E-122 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 141 7.5E-49 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 304 8.8E-114 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 Gene3D G3DSA:3.40.50.1370 131 291 4.2E-122 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 221 231 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_18105 b6c7a164f5dc967993d22d52ce40c9ea 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_18045 2ca57732ecb70253593cd52dcafb0a2a 291 SUPERFAMILY SSF55174 4 61 1.4E-11 T 12-10-2018 TL08_18045 2ca57732ecb70253593cd52dcafb0a2a 291 Pfam PF01728 FtsJ-like methyltransferase 64 246 6.2E-19 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 TL08_18045 2ca57732ecb70253593cd52dcafb0a2a 291 Gene3D G3DSA:3.40.50.150 58 272 2.5E-74 T 12-10-2018 TL08_18045 2ca57732ecb70253593cd52dcafb0a2a 291 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 242 5.1E-59 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 TL08_18045 2ca57732ecb70253593cd52dcafb0a2a 291 Pfam PF01479 S4 domain 5 48 1.4E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_18045 2ca57732ecb70253593cd52dcafb0a2a 291 SUPERFAMILY SSF53335 62 248 2.41E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_18045 2ca57732ecb70253593cd52dcafb0a2a 291 PIRSF PIRSF005578 1 269 1.5E-90 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 TL08_18045 2ca57732ecb70253593cd52dcafb0a2a 291 SMART SM00363 5 72 7.4E-5 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_18045 2ca57732ecb70253593cd52dcafb0a2a 291 Gene3D G3DSA:3.10.290.10 1 57 3.8E-14 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 Pfam PF07702 UTRA domain 107 243 4.5E-35 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 SUPERFAMILY SSF64288 74 250 4.55E-47 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 85 2.0E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 Gene3D G3DSA:3.40.1410.10 91 252 3.2E-44 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 SUPERFAMILY SSF46785 26 96 1.09E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 SMART SM00345 30 86 2.4E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 SMART SM00866 105 243 3.6E-38 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 1.2E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 1.2E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_11395 3cd55b4b47ec3e3936f1b8025f9eafb0 268 Gene3D G3DSA:1.10.10.10 22 90 9.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 SUPERFAMILY SSF54427 225 343 2.51E-12 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 34 353 4.0E-106 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 Gene3D G3DSA:1.10.1740.10 19 114 1.7E-28 T 12-10-2018 TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 63 94 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 212 1.6E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 SUPERFAMILY SSF88946 26 110 4.71E-27 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 SUPERFAMILY SSF88659 154 212 1.08E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 Pfam PF08281 Sigma-70, region 4 157 207 1.7E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 Pfam PF04542 Sigma-70 region 2 42 105 2.9E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 Gene3D G3DSA:3.10.450.50 217 344 4.6E-11 T 12-10-2018 TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 Gene3D G3DSA:1.10.10.10 137 214 5.8E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16540 eb4cf24690e079e92137bc3f5ee62c5d 357 Pfam PF12680 SnoaL-like domain 234 339 2.1E-6 T 12-10-2018 IPR037401 SnoaL-like domain TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 SUPERFAMILY SSF51735 3 230 2.86E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 Gene3D G3DSA:3.40.50.720 1 233 1.0E-74 T 12-10-2018 TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 1.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 1.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 1.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 175 3.5E-6 T 12-10-2018 TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 4.5E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 4.5E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 4.5E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.5E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 4.5E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 4.5E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24105 17ac188e27715a19c6769706ac4ab00c 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 229 2.2E-53 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF52151 1431 1715 2.88E-63 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4772 4787 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF50129 4155 4277 2.67E-24 T 12-10-2018 IPR011032 GroES-like superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00826 3589 3773 2.0E-51 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00826 1797 1952 1.1E-34 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1061 1077 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1435 1729 9.0E-106 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3200 3523 2.0E-109 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 419 716 7.4E-96 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF53901 20 202 4.4E-5 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF08659 KR domain 4456 4634 2.6E-58 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF08659 KR domain 2267 2446 3.7E-60 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF51735 2064 2252 6.69E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM01294 811 874 1.2E-4 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM01294 2555 2622 3.7E-4 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:1.10.1200.10 4726 4817 2.3E-29 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:1.10.1200.10 2535 2627 1.1E-30 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF55048 542 606 2.88E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF51735 3897 4097 1.14E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.30.70.3290 3112 3570 3.5E-154 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:1.10.1200.10 789 880 1.7E-25 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.30.70.3290 332 754 5.9E-132 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF47336 2552 2674 6.28E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF14765 Polyketide synthase dehydratase 3589 3888 6.6E-48 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF14765 Polyketide synthase dehydratase 1797 2055 8.8E-27 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF53901 895 1270 1.36E-100 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2267 2447 1.7E-62 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4456 4636 1.6E-52 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF55048 1555 1620 9.29E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.30.70.3290 1346 1777 3.5E-158 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 898 1148 5.3E-91 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2659 2908 1.6E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF51735 2265 2498 2.53E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF47336 800 912 7.33E-19 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.10.129.110 1786 2061 1.5E-59 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.10.129.110 3578 3894 2.0E-90 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.90.180.10 4122 4450 8.6E-106 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF51735 4241 4408 6.08E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF52151 3196 3503 5.75E-72 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF00107 Zinc-binding dehydrogenase 4279 4370 1.5E-15 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2821 2837 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2581 2596 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF55048 3329 3406 3.92E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF51735 4448 4673 6.2E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00823 Phosphopantetheine attachment site 4745 4817 2.7E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00823 Phosphopantetheine attachment site 806 878 7.5E-21 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00823 Phosphopantetheine attachment site 2554 2626 5.8E-26 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF52151 417 706 8.11E-62 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF47336 4738 4817 8.64E-20 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF00550 Phosphopantetheine attachment site 4748 4813 1.4E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF00550 Phosphopantetheine attachment site 822 874 1.5E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF00550 Phosphopantetheine attachment site 2556 2622 4.6E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 ProSitePatterns PS00012 Phosphopantetheine attachment site. 833 848 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2916 3033 3.4E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1156 1273 4.5E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.40.50.720 4451 4701 1.4E-64 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.40.50.720 2066 2525 5.8E-127 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.40.47.10 2651 3103 3.3E-186 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.40.47.10 891 1344 2.0E-189 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.40.50.11460 3899 4096 2.0E-46 T 12-10-2018 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF00698 Acyl transferase domain 1434 1748 8.3E-85 T 12-10-2018 IPR014043 Acyl transferase TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF00698 Acyl transferase domain 3200 3503 9.3E-57 T 12-10-2018 IPR014043 Acyl transferase TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF00698 Acyl transferase domain 418 735 4.3E-81 T 12-10-2018 IPR014043 Acyl transferase TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 4268 4289 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1276 1397 1.1E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3036 3162 1.3E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.40.366.10 3198 3526 3.5E-154 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.40.366.10 417 719 5.9E-132 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 Gene3D G3DSA:3.40.366.10 1433 1732 3.5E-158 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SUPERFAMILY SSF53901 2657 3031 4.71E-101 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00829 4138 4446 2.0E-146 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00825 Beta-ketoacyl synthase 2661 3086 2.0E-216 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15890 b11f27a4ecaf2e5e9cbf82585686642e 4897 SMART SM00825 Beta-ketoacyl synthase 900 1326 4.8E-216 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 SUPERFAMILY SSF141868 612 858 2.62E-84 T 12-10-2018 IPR035919 EAL domain superfamily TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 Pfam PF00990 Diguanylate cyclase, GGDEF domain 436 587 6.0E-20 T 12-10-2018 IPR000160 GGDEF domain TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 Pfam PF00563 EAL domain 612 845 1.1E-69 T 12-10-2018 IPR001633 EAL domain TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 Gene3D G3DSA:3.20.20.450 606 859 1.9E-92 T 12-10-2018 IPR035919 EAL domain superfamily TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 Gene3D G3DSA:3.30.70.270 432 596 5.0E-29 T 12-10-2018 TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 Gene3D G3DSA:3.30.450.40 290 431 2.1E-12 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 433 587 4.2E-12 T 12-10-2018 IPR000160 GGDEF domain TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 Pfam PF01590 GAF domain 294 421 6.4E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 SMART SM00052 605 850 2.2E-105 T 12-10-2018 IPR001633 EAL domain TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 SMART SM00267 425 598 8.7E-26 T 12-10-2018 IPR000160 GGDEF domain TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 SUPERFAMILY SSF55781 293 434 1.81E-10 T 12-10-2018 TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 SMART SM00065 288 433 3.1E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 TL08_02835 1fc6f41d04e5d5fbb9b65e4ccb8a7472 875 SUPERFAMILY SSF55073 441 589 3.37E-23 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 Gene3D G3DSA:1.10.8.50 124 268 1.6E-36 T 12-10-2018 TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 102 3.0E-6 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 SUPERFAMILY SSF57716 223 268 2.57E-12 T 12-10-2018 TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 Gene3D G3DSA:3.20.190.10 2 123 2.1E-11 T 12-10-2018 IPR035937 MutM-like, N-terminal TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 SUPERFAMILY SSF81624 2 123 1.7E-23 T 12-10-2018 IPR035937 MutM-like, N-terminal TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 Pfam PF06827 Zinc finger found in FPG and IleRS 242 268 2.5E-5 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 SUPERFAMILY SSF46946 121 206 4.71E-23 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 SMART SM01232 122 214 3.7E-30 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 SMART SM00898 2 108 6.5E-19 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TL08_07960 784a11c3bbec52fc889f74c1c5e91c59 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 207 1.3E-18 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TL08_21255 ae28e92e07a0cdf6e2dc309f7b71059e 202 Pfam PF02698 DUF218 domain 36 182 7.3E-23 T 12-10-2018 IPR003848 Domain of unknown function DUF218 TL08_13365 f86878bc93609083328948aaa62bda84 123 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 50 70 - T 12-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 TL08_13365 f86878bc93609083328948aaa62bda84 123 Pfam PF01152 Bacterial-like globin 3 115 2.8E-25 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 TL08_13365 f86878bc93609083328948aaa62bda84 123 PIRSF PIRSF002030 1 118 8.9E-39 T 12-10-2018 IPR016339 Truncated hemoglobin, group 1 TL08_13365 f86878bc93609083328948aaa62bda84 123 Gene3D G3DSA:1.10.490.10 1 122 1.2E-38 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TL08_13365 f86878bc93609083328948aaa62bda84 123 SUPERFAMILY SSF46458 3 116 5.04E-30 T 12-10-2018 IPR009050 Globin-like superfamily TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 SUPERFAMILY SSF69075 325 424 5.49E-15 T 12-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 325 423 1.3E-19 T 12-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 424 2.5E-117 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 Gene3D G3DSA:3.40.50.720 162 317 1.4E-35 T 12-10-2018 TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.8E-41 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 Gene3D G3DSA:3.30.460.30 1 158 7.1E-53 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 12-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 173 310 7.3E-27 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 SUPERFAMILY SSF51735 164 310 7.45E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 SUPERFAMILY SSF69742 1 158 7.85E-42 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TL08_02380 4ef45add4309c67e7509a08bbdaca42b 524 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 421 25.344 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TL08_13695 57af72346f51fd3795d65e8a3d8a215e 206 Pfam PF01300 Telomere recombination 23 198 6.9E-41 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 TL08_13695 57af72346f51fd3795d65e8a3d8a215e 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 2.7E-52 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 TL08_13695 57af72346f51fd3795d65e8a3d8a215e 206 Gene3D G3DSA:3.90.870.10 1 206 2.3E-57 T 12-10-2018 TL08_13695 57af72346f51fd3795d65e8a3d8a215e 206 SUPERFAMILY SSF55821 1 204 6.71E-58 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TL08_26380 e7dab4ab85e7217007f0b51c80787241 267 Gene3D G3DSA:1.20.1440.20 17 187 1.0E-56 T 12-10-2018 IPR023353 LemA-like domain superfamily TL08_26380 e7dab4ab85e7217007f0b51c80787241 267 SUPERFAMILY SSF140478 26 178 1.44E-46 T 12-10-2018 IPR023353 LemA-like domain superfamily TL08_26380 e7dab4ab85e7217007f0b51c80787241 267 Pfam PF04011 LemA family 7 181 7.1E-61 T 12-10-2018 IPR007156 LemA TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 Gene3D G3DSA:3.40.50.1000 326 586 5.0E-79 T 12-10-2018 IPR023214 HAD superfamily TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 120 613 2.2E-80 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 SUPERFAMILY SSF81665 97 606 1.44E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 SUPERFAMILY SSF56784 344 634 5.26E-47 T 12-10-2018 IPR036412 HAD-like superfamily TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 Gene3D G3DSA:3.40.1110.10 356 467 5.0E-79 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 347 353 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 196 210 3.6E-25 T 12-10-2018 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 345 359 3.6E-25 T 12-10-2018 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 471 3.6E-25 T 12-10-2018 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 3.6E-25 T 12-10-2018 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 558 570 3.6E-25 T 12-10-2018 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 482 492 3.6E-25 T 12-10-2018 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 PRINTS PR00941 Cadmium-transporting ATPase signature 231 245 5.9E-5 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 PRINTS PR00941 Cadmium-transporting ATPase signature 212 228 5.9E-5 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 PRINTS PR00941 Cadmium-transporting ATPase signature 131 151 5.9E-5 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 96 638 1.3E-146 T 12-10-2018 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 SUPERFAMILY SSF81653 149 246 1.57E-19 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 Gene3D G3DSA:2.70.150.20 135 250 2.4E-30 T 12-10-2018 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 97 636 1.0E-166 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 Pfam PF00122 E1-E2 ATPase 147 322 6.0E-43 T 12-10-2018 TL08_05375 858d70964366aa2e9988b10ff8f7546c 663 Pfam PF00702 haloacid dehalogenase-like hydrolase 342 547 1.6E-38 T 12-10-2018 TL08_23425 a35fbba6251a90945bc1b63259f4edab 364 SUPERFAMILY SSF53756 22 363 2.32E-58 T 12-10-2018 TL08_23425 a35fbba6251a90945bc1b63259f4edab 364 Gene3D G3DSA:3.40.50.2000 181 343 3.9E-49 T 12-10-2018 TL08_23425 a35fbba6251a90945bc1b63259f4edab 364 Gene3D G3DSA:3.40.50.2000 24 359 3.9E-49 T 12-10-2018 TL08_23425 a35fbba6251a90945bc1b63259f4edab 364 Pfam PF13692 Glycosyl transferases group 1 204 327 2.8E-20 T 12-10-2018 TL08_23425 a35fbba6251a90945bc1b63259f4edab 364 Pfam PF13579 Glycosyl transferase 4-like domain 24 180 8.5E-11 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 Gene3D G3DSA:2.60.34.10 491 645 6.4E-17 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 SUPERFAMILY SSF100920 493 593 6.67E-12 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 Pfam PF00012 Hsp70 protein 9 371 9.3E-64 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 Pfam PF00012 Hsp70 protein 494 710 2.4E-8 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 11 18 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 SUPERFAMILY SSF53067 9 166 1.08E-32 T 12-10-2018 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 Gene3D G3DSA:3.90.640.10 208 294 2.3E-94 T 12-10-2018 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 PRINTS PR00301 70kDa heat shock protein signature 353 373 4.0E-16 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 PRINTS PR00301 70kDa heat shock protein signature 7 20 4.0E-16 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 PRINTS PR00301 70kDa heat shock protein signature 121 141 4.0E-16 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 PRINTS PR00301 70kDa heat shock protein signature 319 335 4.0E-16 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 PRINTS PR00301 70kDa heat shock protein signature 182 192 4.0E-16 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 Gene3D G3DSA:3.30.420.40 169 355 2.3E-94 T 12-10-2018 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 Gene3D G3DSA:3.30.420.40 10 365 2.3E-94 T 12-10-2018 TL08_18935 f1fc1e301c0491f8a18eef7c153cb257 828 SUPERFAMILY SSF53067 171 369 1.88E-34 T 12-10-2018 TL08_11900 453fe1b44a04a7ca933319766581b462 268 Gene3D G3DSA:3.90.226.10 13 265 5.5E-58 T 12-10-2018 TL08_11900 453fe1b44a04a7ca933319766581b462 268 SUPERFAMILY SSF52096 17 259 5.39E-55 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_11900 453fe1b44a04a7ca933319766581b462 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 253 2.2E-37 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TL08_11900 453fe1b44a04a7ca933319766581b462 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 122 142 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 SUPERFAMILY SSF46565 3 102 6.41E-30 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 383 36.504 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 SUPERFAMILY SSF57938 133 213 2.49E-17 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 Pfam PF00684 DnaJ central domain 146 210 1.2E-11 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 SUPERFAMILY SSF49493 114 265 2.35E-16 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 Pfam PF00226 DnaJ domain 4 65 4.6E-23 T 12-10-2018 IPR001623 DnaJ domain TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 SUPERFAMILY SSF49493 262 351 3.92E-19 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 Gene3D G3DSA:2.10.230.10 146 210 1.5E-31 T 12-10-2018 TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 PRINTS PR00625 DnaJ domain signature 6 24 1.3E-21 T 12-10-2018 IPR001623 DnaJ domain TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 PRINTS PR00625 DnaJ domain signature 60 79 1.3E-21 T 12-10-2018 IPR001623 DnaJ domain TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 PRINTS PR00625 DnaJ domain signature 40 60 1.3E-21 T 12-10-2018 IPR001623 DnaJ domain TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 PRINTS PR00625 DnaJ domain signature 24 39 1.3E-21 T 12-10-2018 IPR001623 DnaJ domain TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 Pfam PF01556 DnaJ C terminal domain 121 340 1.4E-35 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 Gene3D G3DSA:2.60.260.20 116 252 1.5E-31 T 12-10-2018 TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 SMART SM00271 3 60 5.3E-28 T 12-10-2018 IPR001623 DnaJ domain TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 Gene3D G3DSA:1.10.287.110 1 111 9.4E-29 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TL08_21400 cea0bbd900c50f7822bbee8a8dfedd79 387 Gene3D G3DSA:2.60.260.20 257 370 2.0E-27 T 12-10-2018 TL08_08525 740eb993a01c6f18fd86a93d9812db38 298 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 59 280 1.3E-46 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_08525 740eb993a01c6f18fd86a93d9812db38 298 Gene3D G3DSA:3.40.190.10 147 248 2.6E-60 T 12-10-2018 TL08_08525 740eb993a01c6f18fd86a93d9812db38 298 SMART SM00079 58 285 0.0097 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 TL08_08525 740eb993a01c6f18fd86a93d9812db38 298 Gene3D G3DSA:3.40.190.10 60 280 2.6E-60 T 12-10-2018 TL08_08525 740eb993a01c6f18fd86a93d9812db38 298 SMART SM00062 58 286 3.4E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_08525 740eb993a01c6f18fd86a93d9812db38 298 SUPERFAMILY SSF53850 1 280 3.1E-52 T 12-10-2018 TL08_08525 740eb993a01c6f18fd86a93d9812db38 298 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 82 95 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 251 7.8E-25 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 365 3.1E-26 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 Gene3D G3DSA:3.40.120.10 5 139 1.4E-44 T 12-10-2018 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 370 447 2.1E-15 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 Gene3D G3DSA:3.40.120.10 248 365 4.2E-36 T 12-10-2018 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 SUPERFAMILY SSF53738 7 122 8.24E-30 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 Gene3D G3DSA:3.30.310.50 366 449 5.4E-20 T 12-10-2018 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 SUPERFAMILY SSF53738 257 361 1.45E-30 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 Gene3D G3DSA:3.40.120.10 170 247 2.1E-32 T 12-10-2018 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 131 1.2E-30 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 231 246 5.1E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 168 187 5.1E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 5.1E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 202 215 5.1E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 SUPERFAMILY SSF55957 365 448 9.94E-18 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23355 80e3b15bcc09bb7e77d5502f765ffde2 449 SUPERFAMILY SSF53738 152 253 7.46E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_04860 5fb582f8e4e0d74feaeab8314a2c6ba5 430 Gene3D G3DSA:3.30.830.10 226 423 5.5E-31 T 12-10-2018 TL08_04860 5fb582f8e4e0d74feaeab8314a2c6ba5 430 SUPERFAMILY SSF63411 237 422 7.5E-18 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TL08_04860 5fb582f8e4e0d74feaeab8314a2c6ba5 430 Gene3D G3DSA:3.30.830.10 2 223 1.1E-58 T 12-10-2018 TL08_04860 5fb582f8e4e0d74feaeab8314a2c6ba5 430 Pfam PF00675 Insulinase (Peptidase family M16) 17 131 4.0E-18 T 12-10-2018 IPR011765 Peptidase M16, N-terminal TL08_04860 5fb582f8e4e0d74feaeab8314a2c6ba5 430 Pfam PF05193 Peptidase M16 inactive domain 173 353 3.1E-19 T 12-10-2018 IPR007863 Peptidase M16, C-terminal TL08_04860 5fb582f8e4e0d74feaeab8314a2c6ba5 430 SUPERFAMILY SSF63411 5 220 1.04E-48 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TL08_26585 515c2fcb4c27c3e96714dc6a3e0a763a 151 PRINTS PR00502 NUDIX hydrolase family signature 33 47 4.6E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_26585 515c2fcb4c27c3e96714dc6a3e0a763a 151 PRINTS PR00502 NUDIX hydrolase family signature 47 62 4.6E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_26585 515c2fcb4c27c3e96714dc6a3e0a763a 151 SUPERFAMILY SSF55811 3 128 1.04E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_26585 515c2fcb4c27c3e96714dc6a3e0a763a 151 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_26585 515c2fcb4c27c3e96714dc6a3e0a763a 151 Pfam PF00293 NUDIX domain 7 118 2.9E-18 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_26585 515c2fcb4c27c3e96714dc6a3e0a763a 151 Gene3D G3DSA:3.90.79.10 5 130 2.7E-28 T 12-10-2018 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 50 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 Gene3D G3DSA:3.10.50.30 81 160 2.6E-9 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 Pfam PF03449 Transcription elongation factor, N-terminal 8 76 2.4E-25 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 PIRSF PIRSF006092 1 159 7.4E-31 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 27.797 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 SUPERFAMILY SSF54534 83 157 1.57E-10 T 12-10-2018 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 Gene3D G3DSA:1.10.287.180 5 76 7.7E-24 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 156 1.4E-12 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TL08_04045 046930c9e7b1399e3c9b28a5885ec937 162 SUPERFAMILY SSF46557 7 78 2.35E-23 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TL08_09595 813c37a1507f064c7d41fbc06fd9316c 387 Gene3D G3DSA:1.10.10.10 41 85 5.9E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_09595 813c37a1507f064c7d41fbc06fd9316c 387 Pfam PF13404 AsnC-type helix-turn-helix domain 41 80 4.6E-7 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_03670 bada8ae4ac290e1792eea697772bd56c 146 SUPERFAMILY SSF54593 3 143 1.03E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03670 bada8ae4ac290e1792eea697772bd56c 146 Gene3D G3DSA:3.10.180.10 1 146 6.1E-58 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03670 bada8ae4ac290e1792eea697772bd56c 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 130 5.0E-9 T 12-10-2018 TL08_27130 6b49acbfea4c20b8b38a708dcf9e5d43 309 SUPERFAMILY SSF52540 7 307 2.31E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_27130 6b49acbfea4c20b8b38a708dcf9e5d43 309 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 10 308 7.0E-121 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TL08_27130 6b49acbfea4c20b8b38a708dcf9e5d43 309 Hamap MF_00215 Pantothenate kinase [coaA]. 1 309 166.101 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TL08_27130 6b49acbfea4c20b8b38a708dcf9e5d43 309 Gene3D G3DSA:3.40.50.300 2 309 1.8E-91 T 12-10-2018 TL08_27130 6b49acbfea4c20b8b38a708dcf9e5d43 309 PIRSF PIRSF000545 1 309 5.4E-136 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TL08_27130 6b49acbfea4c20b8b38a708dcf9e5d43 309 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 89 224 1.7E-11 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 SUPERFAMILY SSF55347 116 226 1.33E-37 T 12-10-2018 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 Gene3D G3DSA:3.40.50.720 13 244 3.9E-82 T 12-10-2018 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 54 254 9.2E-55 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 11 115 1.1E-23 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 137 154 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 Gene3D G3DSA:3.30.360.10 116 224 3.9E-82 T 12-10-2018 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 PIRSF PIRSF000161 9 256 3.2E-64 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 118 245 4.8E-30 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 11 255 28.454 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_09300 fd96bd9af419e015d2616458d48d0503 256 SUPERFAMILY SSF51735 9 142 1.39E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 112 123 7.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 198 217 7.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 179 187 7.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 Gene3D G3DSA:3.40.50.720 5 287 9.7E-68 T 12-10-2018 TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 SUPERFAMILY SSF51735 7 284 2.3E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 185 213 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 50 284 8.4E-43 T 12-10-2018 TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 236 1.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 249 269 1.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 217 1.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19415 3ee6377ebbb14fc5be12b075a7f51d67 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 189 1.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12325 c808c18033c5cab3b6ccaeb93b55e9ba 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 142 1.3E-9 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase TL08_12325 c808c18033c5cab3b6ccaeb93b55e9ba 145 SUPERFAMILY SSF55961 1 116 1.32E-19 T 12-10-2018 TL08_12325 c808c18033c5cab3b6ccaeb93b55e9ba 145 Gene3D G3DSA:3.30.530.20 2 144 9.6E-28 T 12-10-2018 IPR023393 START-like domain superfamily TL08_12240 94525d49e8759123a11838c729bef9cd 538 Pfam PF00005 ABC transporter 19 170 1.3E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12240 94525d49e8759123a11838c729bef9cd 538 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12240 94525d49e8759123a11838c729bef9cd 538 SUPERFAMILY SSF52540 2 232 8.5E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12240 94525d49e8759123a11838c729bef9cd 538 Gene3D G3DSA:3.40.50.300 272 514 1.7E-49 T 12-10-2018 TL08_12240 94525d49e8759123a11838c729bef9cd 538 SMART SM00382 28 227 2.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12240 94525d49e8759123a11838c729bef9cd 538 SMART SM00382 311 492 1.7E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12240 94525d49e8759123a11838c729bef9cd 538 Pfam PF00005 ABC transporter 303 443 9.3E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12240 94525d49e8759123a11838c729bef9cd 538 SUPERFAMILY SSF52540 279 507 1.18E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12240 94525d49e8759123a11838c729bef9cd 538 Gene3D G3DSA:3.40.50.300 1 238 1.2E-61 T 12-10-2018 TL08_07280 91d2fd70fdf8542d977df860408ebf70 290 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 191 197 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TL08_07280 91d2fd70fdf8542d977df860408ebf70 290 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 28 282 1.6E-62 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TL08_07280 91d2fd70fdf8542d977df860408ebf70 290 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 18 286 1.7E-38 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 TL08_07280 91d2fd70fdf8542d977df860408ebf70 290 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 286 36.339 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TL08_07280 91d2fd70fdf8542d977df860408ebf70 290 Pfam PF05175 Methyltransferase small domain 113 198 1.9E-12 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TL08_07280 91d2fd70fdf8542d977df860408ebf70 290 Gene3D G3DSA:3.40.50.150 86 289 1.8E-48 T 12-10-2018 TL08_07280 91d2fd70fdf8542d977df860408ebf70 290 SUPERFAMILY SSF53335 13 283 3.06E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_07280 91d2fd70fdf8542d977df860408ebf70 290 Gene3D G3DSA:1.10.8.10 6 79 6.9E-10 T 12-10-2018 TL08_10100 c0d2c5d85ead2204478be456011684df 196 SUPERFAMILY SSF46689 15 84 3.19E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_10100 c0d2c5d85ead2204478be456011684df 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10100 c0d2c5d85ead2204478be456011684df 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 4.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10100 c0d2c5d85ead2204478be456011684df 196 Gene3D G3DSA:1.10.357.10 1 196 4.7E-58 T 12-10-2018 TL08_10100 c0d2c5d85ead2204478be456011684df 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.1E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10100 c0d2c5d85ead2204478be456011684df 196 SUPERFAMILY SSF48498 86 192 1.0E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_14335 c3b96cfc6aacdf3aba5323e339f924db 117 SUPERFAMILY SSF51182 20 115 1.43E-8 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_14335 c3b96cfc6aacdf3aba5323e339f924db 117 Gene3D G3DSA:2.60.120.10 27 112 9.7E-7 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_14660 8b29a97d69b46c932ab8c1eb81f6bcc5 287 SUPERFAMILY SSF48179 190 287 1.79E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_14660 8b29a97d69b46c932ab8c1eb81f6bcc5 287 Gene3D G3DSA:3.40.50.720 7 191 5.5E-56 T 12-10-2018 TL08_14660 8b29a97d69b46c932ab8c1eb81f6bcc5 287 PIRSF PIRSF000105 1 287 1.5E-80 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 TL08_14660 8b29a97d69b46c932ab8c1eb81f6bcc5 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 286 1.5E-30 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TL08_14660 8b29a97d69b46c932ab8c1eb81f6bcc5 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 187 1.0E-53 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TL08_14660 8b29a97d69b46c932ab8c1eb81f6bcc5 287 Gene3D G3DSA:1.10.1040.10 192 287 5.8E-31 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TL08_14660 8b29a97d69b46c932ab8c1eb81f6bcc5 287 SUPERFAMILY SSF51735 8 187 1.36E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_20625 8deac054476f7117096609beedfce776 710 SUPERFAMILY SSF52096 36 317 2.57E-41 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_20625 8deac054476f7117096609beedfce776 710 SUPERFAMILY SSF51735 338 522 3.89E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_20625 8deac054476f7117096609beedfce776 710 Gene3D G3DSA:3.40.50.720 338 525 4.2E-62 T 12-10-2018 TL08_20625 8deac054476f7117096609beedfce776 710 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 341 520 4.4E-57 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TL08_20625 8deac054476f7117096609beedfce776 710 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 524 605 2.4E-12 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TL08_20625 8deac054476f7117096609beedfce776 710 Gene3D G3DSA:3.90.226.10 32 332 1.0E-55 T 12-10-2018 TL08_20625 8deac054476f7117096609beedfce776 710 Pfam PF00378 Enoyl-CoA hydratase/isomerase 79 238 2.2E-25 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TL08_20625 8deac054476f7117096609beedfce776 710 SUPERFAMILY SSF48179 522 624 1.28E-15 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_20625 8deac054476f7117096609beedfce776 710 Gene3D G3DSA:1.10.1040.50 526 705 5.6E-34 T 12-10-2018 TL08_20625 8deac054476f7117096609beedfce776 710 SUPERFAMILY SSF48179 635 702 3.49E-12 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 250 6.6E-60 T 12-10-2018 TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.5E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.5E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.5E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.5E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.5E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.5E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 Gene3D G3DSA:3.40.50.720 5 253 2.6E-77 T 12-10-2018 TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 SUPERFAMILY SSF51735 7 252 1.95E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 5.0E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 5.0E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 5.0E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 7 253 2.2E-102 T 12-10-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.127|MetaCyc: PWY-6507|MetaCyc: PWY-7562 TL08_17700 40ca8d40c0c57d2343d1dcf03dcf3b23 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 179 0.0076 T 12-10-2018 TL08_21725 4f1c20f1dd16fbffe5af3e63e45d018d 347 Gene3D G3DSA:3.90.1720.10 138 345 1.8E-46 T 12-10-2018 TL08_21725 4f1c20f1dd16fbffe5af3e63e45d018d 347 SUPERFAMILY SSF54001 224 345 7.36E-37 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TL08_21725 4f1c20f1dd16fbffe5af3e63e45d018d 347 Pfam PF00877 NlpC/P60 family 243 337 1.4E-23 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain TL08_20275 d2dd923644c5b546b87bafac47951682 756 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 443 449 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TL08_20275 d2dd923644c5b546b87bafac47951682 756 Gene3D G3DSA:3.30.70.100 9 79 1.1E-18 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 163 743 4.4E-169 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TL08_20275 d2dd923644c5b546b87bafac47951682 756 Gene3D G3DSA:3.40.50.1000 422 693 1.8E-86 T 12-10-2018 IPR023214 HAD superfamily TL08_20275 d2dd923644c5b546b87bafac47951682 756 SUPERFAMILY SSF56784 439 740 1.65E-51 T 12-10-2018 IPR036412 HAD-like superfamily TL08_20275 d2dd923644c5b546b87bafac47951682 756 ProSitePatterns PS01047 Heavy-metal-associated domain. 18 46 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TL08_20275 d2dd923644c5b546b87bafac47951682 756 Gene3D G3DSA:3.40.1110.10 452 573 1.8E-86 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TL08_20275 d2dd923644c5b546b87bafac47951682 756 SUPERFAMILY SSF81665 342 433 1.12E-12 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TL08_20275 d2dd923644c5b546b87bafac47951682 756 Pfam PF00403 Heavy-metal-associated domain 20 74 2.4E-10 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TL08_20275 d2dd923644c5b546b87bafac47951682 756 Pfam PF00122 E1-E2 ATPase 242 419 2.5E-50 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 206 744 2.9E-143 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 SUPERFAMILY SSF81653 246 338 8.11E-22 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TL08_20275 d2dd923644c5b546b87bafac47951682 756 SUPERFAMILY SSF55008 11 79 1.7E-18 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 588 598 1.2E-24 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 641 660 1.2E-24 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 291 305 1.2E-24 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 441 455 1.2E-24 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 664 676 1.2E-24 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 216 721 2.3E-80 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00943 Copper-transporting ATPase signature 364 378 7.6E-7 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00943 Copper-transporting ATPase signature 55 75 7.6E-7 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00943 Copper-transporting ATPase signature 424 439 7.6E-7 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00943 Copper-transporting ATPase signature 148 167 7.6E-7 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 PRINTS PR00943 Copper-transporting ATPase signature 618 635 7.6E-7 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 ProSitePatterns PS01229 Hypothetical cof family signature 2. 641 663 - T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 Gene3D G3DSA:2.70.150.20 234 346 2.7E-28 T 12-10-2018 TL08_20275 d2dd923644c5b546b87bafac47951682 756 Pfam PF00702 haloacid dehalogenase-like hydrolase 437 655 6.7E-43 T 12-10-2018 TL08_08155 af311ef815918c62b7ab15308c3e2f23 951 Gene3D G3DSA:2.40.50.140 369 459 1.5E-28 T 12-10-2018 TL08_08155 af311ef815918c62b7ab15308c3e2f23 951 Pfam PF00575 S1 RNA binding domain 375 452 8.1E-5 T 12-10-2018 IPR003029 S1 domain GO:0003676 TL08_08155 af311ef815918c62b7ab15308c3e2f23 951 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 351 752 2.9E-150 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 TL08_08155 af311ef815918c62b7ab15308c3e2f23 951 SUPERFAMILY SSF50249 376 459 6.2E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_08155 af311ef815918c62b7ab15308c3e2f23 951 SMART SM00316 374 453 1.6E-7 T 12-10-2018 IPR022967 RNA-binding domain, S1 TL08_08155 af311ef815918c62b7ab15308c3e2f23 951 Pfam PF10150 Ribonuclease E/G family 455 726 5.0E-102 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TL08_08155 af311ef815918c62b7ab15308c3e2f23 951 Gene3D G3DSA:1.10.10.2480 25 85 1.4E-7 T 12-10-2018 TL08_08155 af311ef815918c62b7ab15308c3e2f23 951 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 24 72 2.4E-9 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal TL08_00085 edb3a6da5c3885a21d17484f5f22f3d3 309 Gene3D G3DSA:1.20.1540.10 77 269 6.2E-38 T 12-10-2018 IPR035952 Rhomboid-like superfamily TL08_00085 edb3a6da5c3885a21d17484f5f22f3d3 309 Pfam PF01694 Rhomboid family 125 255 9.5E-29 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TL08_00085 edb3a6da5c3885a21d17484f5f22f3d3 309 SUPERFAMILY SSF144091 80 265 2.62E-42 T 12-10-2018 TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 SUPERFAMILY SSF49265 61 141 5.28E-6 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 463 809 2.8E-41 T 12-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 354 454 1.0E-6 T 12-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 178 328 1.6E-15 T 12-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 SUPERFAMILY SSF48208 464 885 3.66E-39 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 Gene3D G3DSA:2.60.420.10 462 882 5.5E-107 T 12-10-2018 TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 Gene3D G3DSA:2.60.120.260 337 456 7.7E-11 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 820 885 9.6E-7 T 12-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 Gene3D G3DSA:2.60.120.260 143 328 1.3E-36 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 Gene3D G3DSA:2.60.40.10 38 142 3.4E-26 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_18850 b542d8b4ff655bc823d7f0b45b9c0279 927 Gene3D G3DSA:1.50.10.10 469 818 5.5E-107 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_13295 e03e0879082450ac5887f2538988fd5e 460 Gene3D G3DSA:3.40.50.720 8 164 2.2E-11 T 12-10-2018 TL08_13295 e03e0879082450ac5887f2538988fd5e 460 SUPERFAMILY SSF51735 71 152 3.41E-7 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_13295 e03e0879082450ac5887f2538988fd5e 460 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 74 150 2.5E-5 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TL08_02715 bfcd4ede971588c359f331f7580d3e09 224 SUPERFAMILY SSF46894 120 217 6.24E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_02715 bfcd4ede971588c359f331f7580d3e09 224 Gene3D G3DSA:1.10.10.10 126 223 2.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_02715 bfcd4ede971588c359f331f7580d3e09 224 Pfam PF00072 Response regulator receiver domain 3 112 8.8E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_02715 bfcd4ede971588c359f331f7580d3e09 224 SUPERFAMILY SSF52172 1 118 1.99E-31 T 12-10-2018 IPR011006 CheY-like superfamily TL08_02715 bfcd4ede971588c359f331f7580d3e09 224 SMART SM00862 145 217 1.2E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_02715 bfcd4ede971588c359f331f7580d3e09 224 SMART SM00448 1 112 8.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_02715 bfcd4ede971588c359f331f7580d3e09 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 216 7.4E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_02715 bfcd4ede971588c359f331f7580d3e09 224 Gene3D G3DSA:3.40.50.2300 1 125 3.8E-31 T 12-10-2018 TL08_01950 823a5df8055c1f225977f57fdea1646b 419 Pfam PF13416 Bacterial extracellular solute-binding protein 59 356 2.9E-44 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_01950 823a5df8055c1f225977f57fdea1646b 419 Gene3D G3DSA:3.40.190.10 148 400 4.9E-97 T 12-10-2018 TL08_01950 823a5df8055c1f225977f57fdea1646b 419 SUPERFAMILY SSF53850 36 406 3.4E-79 T 12-10-2018 TL08_01950 823a5df8055c1f225977f57fdea1646b 419 Gene3D G3DSA:3.40.190.10 61 371 4.9E-97 T 12-10-2018 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 201 3.8E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 2.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 2.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 2.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 Gene3D G3DSA:3.40.50.12740 5 208 1.1E-63 T 12-10-2018 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 SUPERFAMILY SSF46894 135 208 1.87E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 SMART SM00448 5 119 8.5E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 Pfam PF00072 Response regulator receiver domain 8 119 3.8E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 SUPERFAMILY SSF52172 4 137 2.28E-29 T 12-10-2018 IPR011006 CheY-like superfamily TL08_18960 5cbe7d54cc10eaee1d21311d6698dca8 210 SMART SM00421 145 202 5.5E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_13185 998c6992d9bb18a3f2cd60523002a142 328 Gene3D G3DSA:1.20.1530.20 12 315 9.4E-22 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TL08_13185 998c6992d9bb18a3f2cd60523002a142 328 Pfam PF01758 Sodium Bile acid symporter family 47 218 3.9E-11 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TL08_15615 3d53de340ffee5e519d1e32af1a59029 495 Pfam PF11066 Protein of unknown function (DUF2867) 328 472 4.7E-37 T 12-10-2018 IPR021295 Protein of unknown function DUF2867 TL08_15615 3d53de340ffee5e519d1e32af1a59029 495 Gene3D G3DSA:3.40.50.720 2 276 9.8E-45 T 12-10-2018 TL08_15615 3d53de340ffee5e519d1e32af1a59029 495 SUPERFAMILY SSF51735 2 236 8.71E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15615 3d53de340ffee5e519d1e32af1a59029 495 Pfam PF13460 NAD(P)H-binding 7 111 9.4E-21 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_15615 3d53de340ffee5e519d1e32af1a59029 495 SUPERFAMILY SSF55961 333 477 9.3E-6 T 12-10-2018 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 Gene3D G3DSA:3.40.220.10 16 172 4.1E-5 T 12-10-2018 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 204 511 8.3E-109 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 Gene3D G3DSA:3.40.630.10 185 519 2.3E-115 T 12-10-2018 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 SUPERFAMILY SSF53187 199 514 1.76E-102 T 12-10-2018 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 367 374 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 PRINTS PR00481 Cytosol aminopeptidase signature 282 299 2.1E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 PRINTS PR00481 Cytosol aminopeptidase signature 363 383 2.1E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 PRINTS PR00481 Cytosol aminopeptidase signature 392 407 2.1E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 PRINTS PR00481 Cytosol aminopeptidase signature 304 325 2.1E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_04615 0c592ccdeea91e575586590f72fb8a6c 523 PRINTS PR00481 Cytosol aminopeptidase signature 341 362 2.1E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 Pfam PF13662 Toprim domain 263 337 2.1E-16 T 12-10-2018 IPR006171 TOPRIM domain TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 Pfam PF08278 DNA primase DnaG DnaB-binding 487 614 3.5E-22 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 Gene3D G3DSA:3.90.980.10 111 243 4.3E-34 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 SUPERFAMILY SSF57783 4 98 2.72E-32 T 12-10-2018 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 Gene3D G3DSA:3.40.1360.10 244 378 9.9E-35 T 12-10-2018 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 SMART SM00766 486 615 1.6E-15 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 TIGRFAM TIGR01391 dnaG: DNA primase 5 427 2.0E-110 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 SUPERFAMILY SSF56731 117 434 1.05E-89 T 12-10-2018 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 3.4E-35 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 SMART SM00400 37 91 5.5E-35 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 Gene3D G3DSA:3.90.580.10 1 101 9.5E-36 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 Hamap MF_00974 DNA primase [dnaG]. 4 620 25.934 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 SMART SM00493 262 344 2.5E-9 T 12-10-2018 IPR006171 TOPRIM domain TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 Pfam PF01807 CHC2 zinc finger 7 99 1.5E-32 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 Pfam PF10410 DnaB-helicase binding domain of primase 381 434 1.3E-16 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 TL08_21235 457d26dbc8d2c345b4f9c6616f556a36 637 PIRSF PIRSF002811 2 626 3.6E-140 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 33.971 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 Gene3D G3DSA:3.30.70.141 1 136 9.2E-56 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 SMART SM00562 2 136 4.1E-70 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 12-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 Pfam PF00334 Nucleoside diphosphate kinase 3 135 1.6E-51 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 SUPERFAMILY SSF54919 3 135 2.23E-52 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 1.4E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.4E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.4E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 1.4E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08115 1ac1ffd9a67d5a78406056faf68157ed 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 1.4E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_11000 36fc087999769d580d5e815750cd3fd3 325 SUPERFAMILY SSF53850 81 311 4.66E-55 T 12-10-2018 TL08_11000 36fc087999769d580d5e815750cd3fd3 325 Gene3D G3DSA:3.40.190.10 181 269 4.3E-74 T 12-10-2018 TL08_11000 36fc087999769d580d5e815750cd3fd3 325 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 114 127 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site TL08_11000 36fc087999769d580d5e815750cd3fd3 325 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 91 310 8.4E-47 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_11000 36fc087999769d580d5e815750cd3fd3 325 Gene3D G3DSA:3.40.190.10 79 310 4.3E-74 T 12-10-2018 TL08_11000 36fc087999769d580d5e815750cd3fd3 325 SMART SM00062 90 312 1.1E-62 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_16940 d3e3dfda7cd5052825afd19045a12dd5 317 Gene3D G3DSA:1.10.3720.10 31 304 1.1E-63 T 12-10-2018 IPR035906 MetI-like superfamily TL08_16940 d3e3dfda7cd5052825afd19045a12dd5 317 SUPERFAMILY SSF161098 35 317 3.53E-69 T 12-10-2018 IPR035906 MetI-like superfamily TL08_16940 d3e3dfda7cd5052825afd19045a12dd5 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 127 310 1.1E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_23045 17baa52c0f9ce5399ac836c1e3329094 450 SUPERFAMILY SSF51556 53 376 4.0E-63 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_23045 17baa52c0f9ce5399ac836c1e3329094 450 Gene3D G3DSA:2.30.40.10 21 429 5.0E-134 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_23045 17baa52c0f9ce5399ac836c1e3329094 450 Gene3D G3DSA:3.20.20.140 55 432 5.0E-134 T 12-10-2018 TL08_23045 17baa52c0f9ce5399ac836c1e3329094 450 Pfam PF01979 Amidohydrolase family 51 424 4.4E-40 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_23045 17baa52c0f9ce5399ac836c1e3329094 450 SUPERFAMILY SSF51338 356 449 3.1E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_23045 17baa52c0f9ce5399ac836c1e3329094 450 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 4 444 1.2E-133 T 12-10-2018 IPR010252 Formiminoglutamate deiminase TL08_15410 0c82fba1b52677cfdbba4ceaee86d141 319 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_15410 0c82fba1b52677cfdbba4ceaee86d141 319 Gene3D G3DSA:3.40.50.300 1 259 1.4E-66 T 12-10-2018 TL08_15410 0c82fba1b52677cfdbba4ceaee86d141 319 Pfam PF00005 ABC transporter 23 164 5.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_15410 0c82fba1b52677cfdbba4ceaee86d141 319 SMART SM00382 30 214 1.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_15410 0c82fba1b52677cfdbba4ceaee86d141 319 SUPERFAMILY SSF52540 2 226 2.09E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 Pfam PF00012 Hsp70 protein 88 350 8.7E-29 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 Gene3D G3DSA:3.30.420.40 5 349 8.1E-94 T 12-10-2018 TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 SUPERFAMILY SSF53067 3 156 1.26E-20 T 12-10-2018 TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 Gene3D G3DSA:3.90.640.10 203 290 8.1E-94 T 12-10-2018 TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 312 326 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 SUPERFAMILY SSF53067 166 350 9.36E-32 T 12-10-2018 TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 PRINTS PR00301 70kDa heat shock protein signature 309 325 2.1E-6 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 PRINTS PR00301 70kDa heat shock protein signature 177 187 2.1E-6 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 PRINTS PR00301 70kDa heat shock protein signature 2 15 2.1E-6 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_21510 1e4f54d363aa27489961eb6be17c9279 646 Gene3D G3DSA:3.30.420.40 165 340 8.1E-94 T 12-10-2018 TL08_17095 70db57e13262d3a19913b8ae84f8458e 199 SUPERFAMILY SSF52540 18 193 3.98E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17095 70db57e13262d3a19913b8ae84f8458e 199 Gene3D G3DSA:3.40.50.300 13 193 4.4E-15 T 12-10-2018 TL08_17095 70db57e13262d3a19913b8ae84f8458e 199 Pfam PF03029 Conserved hypothetical ATP binding protein 24 191 1.5E-22 T 12-10-2018 IPR004130 GPN-loop GTPase TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 ProSitePatterns PS00683 Rhodanese C-terminal signature. 258 268 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 Gene3D G3DSA:3.40.250.10 1 147 4.3E-42 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 SUPERFAMILY SSF52821 147 279 1.31E-27 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 Pfam PF00581 Rhodanese-like domain 164 269 2.0E-8 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 Pfam PF00581 Rhodanese-like domain 7 126 1.8E-17 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 ProSitePatterns PS00380 Rhodanese signature 1. 38 49 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 SMART SM00450 151 274 1.3E-14 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 SMART SM00450 6 130 2.1E-24 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 SUPERFAMILY SSF52821 2 148 5.11E-36 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_08675 275a5c40da9685aec135f5ec32ef6bf2 283 Gene3D G3DSA:3.40.250.10 155 277 1.4E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_14655 bb3090224ec77202f19990529814b226 448 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 65 187 7.1E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_14655 bb3090224ec77202f19990529814b226 448 Gene3D G3DSA:3.90.180.10 15 434 7.4E-216 T 12-10-2018 TL08_14655 bb3090224ec77202f19990529814b226 448 Gene3D G3DSA:3.40.50.720 216 362 7.4E-216 T 12-10-2018 TL08_14655 bb3090224ec77202f19990529814b226 448 SUPERFAMILY SSF51735 192 379 2.95E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14655 bb3090224ec77202f19990529814b226 448 SMART SM00829 46 412 8.5E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_14655 bb3090224ec77202f19990529814b226 448 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 32 424 1.6E-170 T 12-10-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 TL08_14655 bb3090224ec77202f19990529814b226 448 SUPERFAMILY SSF50129 49 227 2.2E-30 T 12-10-2018 IPR011032 GroES-like superfamily TL08_14655 bb3090224ec77202f19990529814b226 448 Pfam PF00107 Zinc-binding dehydrogenase 233 376 3.9E-28 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_05090 f45c132bf574fc94e6204769bc525eaf 1905 Gene3D G3DSA:1.25.40.10 937 1192 2.2E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05090 f45c132bf574fc94e6204769bc525eaf 1905 SUPERFAMILY SSF48452 1152 1355 3.99E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05090 f45c132bf574fc94e6204769bc525eaf 1905 Pfam PF12770 CHAT domain 1616 1904 1.3E-45 T 12-10-2018 IPR024983 CHAT domain TL08_05090 f45c132bf574fc94e6204769bc525eaf 1905 Gene3D G3DSA:1.25.40.10 755 936 4.1E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05090 f45c132bf574fc94e6204769bc525eaf 1905 Gene3D G3DSA:1.25.40.10 1210 1403 7.2E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_02700 eff19567595909799e367be1272f6aaf 167 SUPERFAMILY SSF54909 67 149 9.12E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_02700 eff19567595909799e367be1272f6aaf 167 SMART SM00344 4 111 2.6E-30 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TL08_02700 eff19567595909799e367be1272f6aaf 167 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TL08_02700 eff19567595909799e367be1272f6aaf 167 Gene3D G3DSA:3.30.70.920 55 145 4.5E-15 T 12-10-2018 TL08_02700 eff19567595909799e367be1272f6aaf 167 SUPERFAMILY SSF46785 3 64 1.92E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_02700 eff19567595909799e367be1272f6aaf 167 Pfam PF01037 Lrp/AsnC ligand binding domain 88 140 4.7E-10 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TL08_02700 eff19567595909799e367be1272f6aaf 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.2E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_02700 eff19567595909799e367be1272f6aaf 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.2E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_02700 eff19567595909799e367be1272f6aaf 167 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.2E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_02700 eff19567595909799e367be1272f6aaf 167 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 2.6E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_02700 eff19567595909799e367be1272f6aaf 167 Gene3D G3DSA:1.10.10.10 1 54 1.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 SUPERFAMILY SSF51905 6 304 1.55E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 304 2.4E-120 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.7E-34 T 12-10-2018 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.7E-34 T 12-10-2018 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-34 T 12-10-2018 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 1.7E-34 T 12-10-2018 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.7E-34 T 12-10-2018 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 Gene3D G3DSA:3.50.50.60 116 238 1.3E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 4.3E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 4.3E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 253 4.3E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 285 4.3E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 194 210 4.3E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 4.3E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 4.3E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 4.3E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 4.3E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 293 3.1E-48 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 Gene3D G3DSA:3.50.50.60 7 298 1.3E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_27085 22c56eb01cc845d8ea0c30a8c87f8ef1 327 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 SUPERFAMILY SSF51735 3 239 1.35E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 9.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 238 1.8E-36 T 12-10-2018 TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 Gene3D G3DSA:3.40.50.720 1 239 5.8E-52 T 12-10-2018 TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 4.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 4.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_22420 f19b7e695c1bc18c4802f95f0dda571a 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 4.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14110 f7c0f27f87f86262200cd34d2a3b7221 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 3.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14110 f7c0f27f87f86262200cd34d2a3b7221 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 127 140 3.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14110 f7c0f27f87f86262200cd34d2a3b7221 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 69 84 3.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14110 f7c0f27f87f86262200cd34d2a3b7221 275 Gene3D G3DSA:3.40.50.1820 27 262 1.9E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14110 f7c0f27f87f86262200cd34d2a3b7221 275 Pfam PF12697 Alpha/beta hydrolase family 46 252 6.8E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14110 f7c0f27f87f86262200cd34d2a3b7221 275 SUPERFAMILY SSF53474 28 260 4.95E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_11775 1813438abccd1be1561a5e54602bc51a 160 Pfam PF12802 MarR family 26 79 1.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_11775 1813438abccd1be1561a5e54602bc51a 160 Gene3D G3DSA:1.10.10.10 2 91 1.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11775 1813438abccd1be1561a5e54602bc51a 160 SUPERFAMILY SSF46785 33 149 1.3E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 Pfam PF00128 Alpha amylase, catalytic domain 188 277 1.7E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 Pfam PF00128 Alpha amylase, catalytic domain 312 529 9.9E-5 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 Gene3D G3DSA:2.60.40.10 1 136 1.0E-44 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 7.1E-18 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 SUPERFAMILY SSF81296 5 147 1.43E-44 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 Gene3D G3DSA:3.20.20.80 138 582 6.2E-184 T 12-10-2018 TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 SUPERFAMILY SSF51011 590 715 2.73E-22 T 12-10-2018 TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 SUPERFAMILY SSF51445 133 576 9.75E-138 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 Gene3D G3DSA:2.60.40.1180 589 715 7.4E-17 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 SMART SM00642 158 568 4.4E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_17790 115c5e9c6d495ca4a7c91234afcebeca 722 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 676 0.0 T 12-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 TL08_22280 63815a7535548d7c19f6251b14e6ebf8 243 Pfam PF01471 Putative peptidoglycan binding domain 44 103 2.4E-12 T 12-10-2018 IPR002477 Peptidoglycan binding-like TL08_22280 63815a7535548d7c19f6251b14e6ebf8 243 SUPERFAMILY SSF55166 117 240 2.04E-30 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TL08_22280 63815a7535548d7c19f6251b14e6ebf8 243 SUPERFAMILY SSF47090 33 108 1.26E-17 T 12-10-2018 IPR036365 PGBD-like superfamily TL08_22280 63815a7535548d7c19f6251b14e6ebf8 243 Gene3D G3DSA:1.10.101.10 31 115 9.3E-27 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TL08_22280 63815a7535548d7c19f6251b14e6ebf8 243 Gene3D G3DSA:3.30.1380.10 117 242 1.4E-36 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TL08_22280 63815a7535548d7c19f6251b14e6ebf8 243 Pfam PF08291 Peptidase M15 117 227 3.3E-24 T 12-10-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 TL08_14710 9a8cb60e41431ce1d47b9ec316951a13 382 Gene3D G3DSA:1.10.260.40 14 78 1.5E-18 T 12-10-2018 TL08_14710 9a8cb60e41431ce1d47b9ec316951a13 382 Pfam PF00356 Bacterial regulatory proteins, lacI family 24 69 1.3E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_14710 9a8cb60e41431ce1d47b9ec316951a13 382 Gene3D G3DSA:3.40.50.2300 190 349 4.2E-37 T 12-10-2018 TL08_14710 9a8cb60e41431ce1d47b9ec316951a13 382 Gene3D G3DSA:3.40.50.2300 107 348 4.2E-37 T 12-10-2018 TL08_14710 9a8cb60e41431ce1d47b9ec316951a13 382 SMART SM00354 19 92 1.8E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_14710 9a8cb60e41431ce1d47b9ec316951a13 382 SUPERFAMILY SSF53822 100 359 4.17E-27 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_14710 9a8cb60e41431ce1d47b9ec316951a13 382 SUPERFAMILY SSF47413 22 76 4.58E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_14710 9a8cb60e41431ce1d47b9ec316951a13 382 Pfam PF13377 Periplasmic binding protein-like domain 198 356 3.2E-19 T 12-10-2018 TL08_02425 0751a38bc9c6d43248d6e3ceec9f5eea 446 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 16 437 93.558 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 TL08_02425 0751a38bc9c6d43248d6e3ceec9f5eea 446 SUPERFAMILY SSF53383 14 433 1.22E-111 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_02425 0751a38bc9c6d43248d6e3ceec9f5eea 446 Pfam PF00202 Aminotransferase class-III 47 430 2.9E-80 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_02425 0751a38bc9c6d43248d6e3ceec9f5eea 446 Gene3D G3DSA:3.90.1150.10 21 424 1.6E-151 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_02425 0751a38bc9c6d43248d6e3ceec9f5eea 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 247 283 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_02425 0751a38bc9c6d43248d6e3ceec9f5eea 446 Gene3D G3DSA:3.40.640.10 82 330 1.6E-151 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_02425 0751a38bc9c6d43248d6e3ceec9f5eea 446 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 17 433 1.8E-176 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 TL08_11515 c4a203573acf21bf412220aad8e21ec6 212 Hamap MF_00328 Guanylate kinase [gmk]. 6 191 35.865 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TL08_11515 c4a203573acf21bf412220aad8e21ec6 212 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 8 187 1.2E-64 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TL08_11515 c4a203573acf21bf412220aad8e21ec6 212 ProSitePatterns PS00856 Guanylate kinase-like signature. 42 59 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TL08_11515 c4a203573acf21bf412220aad8e21ec6 212 SMART SM00072 7 191 1.1E-62 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TL08_11515 c4a203573acf21bf412220aad8e21ec6 212 Gene3D G3DSA:3.30.63.10 39 102 2.4E-63 T 12-10-2018 TL08_11515 c4a203573acf21bf412220aad8e21ec6 212 Gene3D G3DSA:3.40.50.300 9 183 2.4E-63 T 12-10-2018 TL08_11515 c4a203573acf21bf412220aad8e21ec6 212 Pfam PF00625 Guanylate kinase 8 187 3.8E-41 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TL08_11515 c4a203573acf21bf412220aad8e21ec6 212 SUPERFAMILY SSF52540 6 188 9.08E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03375 f7426b2dbf73a2dbf7d506065e6cfc9c 877 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 30 327 4.5E-83 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TL08_03375 f7426b2dbf73a2dbf7d506065e6cfc9c 877 SUPERFAMILY SSF56059 15 355 2.12E-91 T 12-10-2018 TL08_03375 f7426b2dbf73a2dbf7d506065e6cfc9c 877 Gene3D G3DSA:3.30.470.20 198 327 2.2E-41 T 12-10-2018 TL08_03375 f7426b2dbf73a2dbf7d506065e6cfc9c 877 SUPERFAMILY SSF52009 774 874 6.8E-27 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TL08_03375 f7426b2dbf73a2dbf7d506065e6cfc9c 877 Pfam PF00391 PEP-utilising enzyme, mobile domain 800 871 9.7E-21 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TL08_03375 f7426b2dbf73a2dbf7d506065e6cfc9c 877 Gene3D G3DSA:3.30.1490.20 3 197 2.7E-67 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TL08_03375 f7426b2dbf73a2dbf7d506065e6cfc9c 877 Gene3D G3DSA:3.50.30.10 774 876 2.5E-30 T 12-10-2018 TL08_01770 970de3e91230c0d7f0dd4a7397ac7aa5 294 SMART SM00478 40 192 2.9E-41 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TL08_01770 970de3e91230c0d7f0dd4a7397ac7aa5 294 Pfam PF00633 Helix-hairpin-helix motif 101 129 9.9E-7 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 TL08_01770 970de3e91230c0d7f0dd4a7397ac7aa5 294 SUPERFAMILY SSF48150 10 219 9.89E-62 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TL08_01770 970de3e91230c0d7f0dd4a7397ac7aa5 294 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 157 6.2E-17 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TL08_01770 970de3e91230c0d7f0dd4a7397ac7aa5 294 Gene3D G3DSA:1.10.340.30 21 133 6.5E-70 T 12-10-2018 TL08_01770 970de3e91230c0d7f0dd4a7397ac7aa5 294 Gene3D G3DSA:1.10.1670.10 10 213 6.5E-70 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TL08_15085 116aa26445d5c1da727f67cf34bd2034 275 Gene3D G3DSA:3.40.710.10 5 274 1.4E-77 T 12-10-2018 TL08_15085 116aa26445d5c1da727f67cf34bd2034 275 Pfam PF00144 Beta-lactamase 35 251 2.0E-33 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_15085 116aa26445d5c1da727f67cf34bd2034 275 SUPERFAMILY SSF56601 12 267 2.35E-54 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_23720 24cf0c86c781214ae690a7360f4de27b 369 SUPERFAMILY SSF54506 2 166 1.73E-50 T 12-10-2018 TL08_23720 24cf0c86c781214ae690a7360f4de27b 369 Gene3D G3DSA:3.10.310.10 4 356 4.1E-105 T 12-10-2018 TL08_23720 24cf0c86c781214ae690a7360f4de27b 369 SUPERFAMILY SSF54506 170 361 5.18E-44 T 12-10-2018 TL08_23720 24cf0c86c781214ae690a7360f4de27b 369 Pfam PF04303 PrpF protein 2 358 2.4E-97 T 12-10-2018 IPR007400 PrpF protein TL08_23720 24cf0c86c781214ae690a7360f4de27b 369 Gene3D G3DSA:3.10.310.10 165 345 4.1E-105 T 12-10-2018 TL08_08530 4821fceddf8580d4d9f97163c10b92f6 242 Gene3D G3DSA:3.40.50.300 1 242 6.3E-78 T 12-10-2018 TL08_08530 4821fceddf8580d4d9f97163c10b92f6 242 SUPERFAMILY SSF52540 1 235 1.56E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08530 4821fceddf8580d4d9f97163c10b92f6 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_08530 4821fceddf8580d4d9f97163c10b92f6 242 SMART SM00382 26 213 1.0E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08530 4821fceddf8580d4d9f97163c10b92f6 242 Pfam PF00005 ABC transporter 17 165 6.8E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_08530 4821fceddf8580d4d9f97163c10b92f6 242 PIRSF PIRSF039085 1 241 9.9E-111 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 SUPERFAMILY SSF46894 4 95 5.39E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 Gene3D G3DSA:3.40.50.300 265 424 4.4E-28 T 12-10-2018 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 SUPERFAMILY SSF48452 673 823 9.67E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 Pfam PF00931 NB-ARC domain 296 478 1.0E-8 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 SUPERFAMILY SSF48452 101 265 6.45E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 PRINTS PR00364 Disease resistance protein signature 300 315 6.5E-7 T 12-10-2018 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 PRINTS PR00364 Disease resistance protein signature 380 394 6.5E-7 T 12-10-2018 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 PRINTS PR00364 Disease resistance protein signature 468 482 6.5E-7 T 12-10-2018 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 SMART SM01043 102 246 1.9E-5 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 Pfam PF00486 Transcriptional regulatory protein, C terminal 18 95 1.3E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 Gene3D G3DSA:1.25.40.10 800 969 1.6E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 Pfam PF03704 Bacterial transcriptional activator domain 102 243 7.8E-9 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 Pfam PF13374 Tetratricopeptide repeat 759 792 0.0024 T 12-10-2018 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 Gene3D G3DSA:1.10.10.10 1 98 6.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 SUPERFAMILY SSF48452 840 949 8.35E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 SMART SM00862 17 95 1.8E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 Gene3D G3DSA:1.25.40.10 101 264 2.0E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 SUPERFAMILY SSF52540 270 530 7.91E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20015 be12b3c7957e0aec41c2e5d9873e8b2c 972 Gene3D G3DSA:1.25.40.10 671 799 6.9E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 SUPERFAMILY SSF54211 236 406 1.08E-59 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_00030 368aa88f71ba71c40fcce985923a2972 655 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 587 643 2.8E-27 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 ProSitePatterns PS00177 DNA topoisomerase II signature. 437 445 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 235 257 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 196 209 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 389 409 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 485 494 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 375 389 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 181 196 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 608 620 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 327 343 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 624 640 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR01159 DNA gyrase subunit B signature 8 18 1.4E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 175 6.2E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_00030 368aa88f71ba71c40fcce985923a2972 655 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 655 93.05 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 Gene3D G3DSA:3.30.230.10 235 407 1.3E-74 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_00030 368aa88f71ba71c40fcce985923a2972 655 Pfam PF01751 Toprim domain 434 545 1.7E-16 T 12-10-2018 IPR006171 TOPRIM domain TL08_00030 368aa88f71ba71c40fcce985923a2972 655 Gene3D G3DSA:3.30.565.10 4 221 1.6E-84 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_00030 368aa88f71ba71c40fcce985923a2972 655 Pfam PF00204 DNA gyrase B 236 405 1.2E-62 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 Gene3D G3DSA:3.40.50.670 413 655 4.8E-100 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 SMART SM00387 33 176 2.3E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR00418 DNA topoisomerase II family signature 539 551 2.8E-71 T 12-10-2018 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR00418 DNA topoisomerase II family signature 501 517 2.8E-71 T 12-10-2018 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR00418 DNA topoisomerase II family signature 283 296 2.8E-71 T 12-10-2018 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR00418 DNA topoisomerase II family signature 587 603 2.8E-71 T 12-10-2018 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR00418 DNA topoisomerase II family signature 72 85 2.8E-71 T 12-10-2018 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR00418 DNA topoisomerase II family signature 519 536 2.8E-71 T 12-10-2018 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR00418 DNA topoisomerase II family signature 115 129 2.8E-71 T 12-10-2018 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR00418 DNA topoisomerase II family signature 435 449 2.8E-71 T 12-10-2018 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 PRINTS PR00418 DNA topoisomerase II family signature 37 52 2.8E-71 T 12-10-2018 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 655 6.8E-294 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 SUPERFAMILY SSF56719 409 650 4.18E-84 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 SMART SM00433 37 648 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TL08_00030 368aa88f71ba71c40fcce985923a2972 655 SUPERFAMILY SSF55874 8 210 1.83E-69 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_04970 ad21ba3457224c4f739f5f5b6528b2a0 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 3.9E-56 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 TL08_04970 ad21ba3457224c4f739f5f5b6528b2a0 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 4.0E-50 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 TL08_04970 ad21ba3457224c4f739f5f5b6528b2a0 159 SUPERFAMILY SSF74982 4 133 1.96E-51 T 12-10-2018 IPR023620 Small protein B TL08_04970 ad21ba3457224c4f739f5f5b6528b2a0 159 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site TL08_04970 ad21ba3457224c4f739f5f5b6528b2a0 159 Pfam PF01668 SmpB protein 10 150 6.8E-59 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 TL08_04970 ad21ba3457224c4f739f5f5b6528b2a0 159 Gene3D G3DSA:2.40.280.10 3 130 2.6E-47 T 12-10-2018 IPR023620 Small protein B TL08_04970 ad21ba3457224c4f739f5f5b6528b2a0 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 157 71.445 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 TL08_00560 d73f7f193392a83a51e483c3f0b99e08 510 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 475 6.9E-165 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TL08_00560 d73f7f193392a83a51e483c3f0b99e08 510 PIRSF PIRSF006446 1 495 5.3E-133 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TL08_23650 0274da1abe02d89f2b88bde4de51d99a 656 Gene3D G3DSA:3.40.50.1820 274 415 1.8E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_23650 0274da1abe02d89f2b88bde4de51d99a 656 Gene3D G3DSA:3.40.50.1820 56 249 6.8E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_23650 0274da1abe02d89f2b88bde4de51d99a 656 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 70 246 7.8E-22 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 TL08_23650 0274da1abe02d89f2b88bde4de51d99a 656 SUPERFAMILY SSF49785 441 621 6.59E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_23650 0274da1abe02d89f2b88bde4de51d99a 656 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 72 343 5.1E-51 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TL08_23650 0274da1abe02d89f2b88bde4de51d99a 656 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 370 611 4.4E-33 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TL08_23650 0274da1abe02d89f2b88bde4de51d99a 656 SMART SM00939 358 625 1.3E-40 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TL08_23650 0274da1abe02d89f2b88bde4de51d99a 656 SUPERFAMILY SSF53474 40 392 9.74E-68 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_11700 facb6c151e96faa41af335b705c41cf0 734 TIGRFAM TIGR00232 tktlase_bact: transketolase 60 725 9.1E-242 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TL08_11700 facb6c151e96faa41af335b705c41cf0 734 Gene3D G3DSA:3.40.50.970 37 389 7.8E-118 T 12-10-2018 TL08_11700 facb6c151e96faa41af335b705c41cf0 734 SUPERFAMILY SSF52922 595 729 1.11E-39 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_11700 facb6c151e96faa41af335b705c41cf0 734 Gene3D G3DSA:3.40.50.970 390 601 2.4E-85 T 12-10-2018 TL08_11700 facb6c151e96faa41af335b705c41cf0 734 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 58 393 1.3E-139 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_11700 facb6c151e96faa41af335b705c41cf0 734 Gene3D G3DSA:3.40.50.920 602 728 6.1E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_11700 facb6c151e96faa41af335b705c41cf0 734 ProSitePatterns PS00801 Transketolase signature 1. 66 86 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_11700 facb6c151e96faa41af335b705c41cf0 734 Pfam PF02779 Transketolase, pyrimidine binding domain 409 589 3.6E-49 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_11700 facb6c151e96faa41af335b705c41cf0 734 SUPERFAMILY SSF52518 50 379 5.49E-103 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_11700 facb6c151e96faa41af335b705c41cf0 734 ProSitePatterns PS00802 Transketolase signature 2. 532 548 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_11700 facb6c151e96faa41af335b705c41cf0 734 SMART SM00861 410 590 7.6E-74 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_11700 facb6c151e96faa41af335b705c41cf0 734 SUPERFAMILY SSF52518 402 591 1.26E-68 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_11700 facb6c151e96faa41af335b705c41cf0 734 Pfam PF02780 Transketolase, C-terminal domain 612 719 5.4E-14 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TL08_12725 12be77c4c95aecdb67dcf26fd2d5f914 261 SUPERFAMILY SSF53167 17 256 1.7E-52 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TL08_12725 12be77c4c95aecdb67dcf26fd2d5f914 261 Pfam PF01048 Phosphorylase superfamily 30 250 1.0E-33 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TL08_12725 12be77c4c95aecdb67dcf26fd2d5f914 261 Gene3D G3DSA:3.40.50.1580 16 257 1.8E-55 T 12-10-2018 TL08_18130 823221e9396e6617ed3085599b7b80d2 341 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 15 326 8.3E-114 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria TL08_18130 823221e9396e6617ed3085599b7b80d2 341 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 42 73 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_18130 823221e9396e6617ed3085599b7b80d2 341 Gene3D G3DSA:1.10.1740.10 18 107 3.1E-23 T 12-10-2018 TL08_18130 823221e9396e6617ed3085599b7b80d2 341 SUPERFAMILY SSF88946 21 92 4.71E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_18130 823221e9396e6617ed3085599b7b80d2 341 Gene3D G3DSA:3.10.450.50 202 327 1.3E-14 T 12-10-2018 TL08_18130 823221e9396e6617ed3085599b7b80d2 341 Gene3D G3DSA:1.10.10.10 121 196 3.9E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18130 823221e9396e6617ed3085599b7b80d2 341 SUPERFAMILY SSF88659 137 193 4.67E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_18130 823221e9396e6617ed3085599b7b80d2 341 Pfam PF08281 Sigma-70, region 4 140 192 6.9E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_18130 823221e9396e6617ed3085599b7b80d2 341 Pfam PF04542 Sigma-70 region 2 21 88 8.6E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_18130 823221e9396e6617ed3085599b7b80d2 341 SUPERFAMILY SSF54427 207 302 1.84E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_18130 823221e9396e6617ed3085599b7b80d2 341 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 193 2.2E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_18130 823221e9396e6617ed3085599b7b80d2 341 Pfam PF12680 SnoaL-like domain 215 317 3.0E-8 T 12-10-2018 IPR037401 SnoaL-like domain TL08_10060 b8d62cc9d414a5bde84b3370894270be 220 SUPERFAMILY SSF52172 4 181 1.4E-29 T 12-10-2018 IPR011006 CheY-like superfamily TL08_10060 b8d62cc9d414a5bde84b3370894270be 220 SMART SM00421 148 205 2.8E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_10060 b8d62cc9d414a5bde84b3370894270be 220 Pfam PF00072 Response regulator receiver domain 5 117 8.8E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_10060 b8d62cc9d414a5bde84b3370894270be 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_10060 b8d62cc9d414a5bde84b3370894270be 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_10060 b8d62cc9d414a5bde84b3370894270be 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_10060 b8d62cc9d414a5bde84b3370894270be 220 Gene3D G3DSA:3.40.50.12740 4 209 9.3E-62 T 12-10-2018 TL08_10060 b8d62cc9d414a5bde84b3370894270be 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 205 1.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_10060 b8d62cc9d414a5bde84b3370894270be 220 SMART SM00448 3 116 1.0E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 SUPERFAMILY SSF52935 289 435 7.06E-36 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 Gene3D G3DSA:3.40.1380.20 310 436 7.2E-31 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 Pfam PF00224 Pyruvate kinase, barrel domain 1 304 2.6E-105 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 ProSitePatterns PS00110 Pyruvate kinase active site signature. 181 193 - T 12-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 SUPERFAMILY SSF51621 1 305 5.23E-82 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 1 434 2.3E-154 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 Gene3D G3DSA:2.40.33.10 39 133 5.9E-120 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 PRINTS PR01050 Pyruvate kinase family signature 235 259 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 PRINTS PR01050 Pyruvate kinase family signature 27 43 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 PRINTS PR01050 Pyruvate kinase family signature 210 234 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 PRINTS PR01050 Pyruvate kinase family signature 260 278 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 PRINTS PR01050 Pyruvate kinase family signature 152 166 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 PRINTS PR01050 Pyruvate kinase family signature 279 295 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 PRINTS PR01050 Pyruvate kinase family signature 183 209 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 SUPERFAMILY SSF50800 38 132 6.63E-26 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 Gene3D G3DSA:3.20.20.60 1 298 5.9E-120 T 12-10-2018 TL08_17860 7aa3c385c05a6bd80cccca78de2a6513 441 Pfam PF02887 Pyruvate kinase, alpha/beta domain 322 433 1.6E-24 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TL08_22930 fefb353f799cb8dbfe3476aa30b592b8 209 SUPERFAMILY SSF46689 12 80 6.48E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_22930 fefb353f799cb8dbfe3476aa30b592b8 209 Gene3D G3DSA:1.10.357.10 61 201 1.1E-30 T 12-10-2018 TL08_22930 fefb353f799cb8dbfe3476aa30b592b8 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 4.0E-19 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_22930 fefb353f799cb8dbfe3476aa30b592b8 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 8.9E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_22930 fefb353f799cb8dbfe3476aa30b592b8 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 8.9E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_22930 fefb353f799cb8dbfe3476aa30b592b8 209 Gene3D G3DSA:1.10.10.60 17 59 6.0E-22 T 12-10-2018 TL08_22930 fefb353f799cb8dbfe3476aa30b592b8 209 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00359 B-class P450 signature 308 317 1.6E-36 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00359 B-class P450 signature 317 328 1.6E-36 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00359 B-class P450 signature 240 251 1.6E-36 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00359 B-class P450 signature 54 65 1.6E-36 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00359 B-class P450 signature 158 180 1.6E-36 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00359 B-class P450 signature 258 285 1.6E-36 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00359 B-class P450 signature 104 120 1.6E-36 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 Pfam PF00067 Cytochrome P450 48 232 2.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 Pfam PF00067 Cytochrome P450 239 338 3.7E-15 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 Gene3D G3DSA:1.10.630.10 1 371 5.2E-125 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00385 P450 superfamily signature 308 317 3.9E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00385 P450 superfamily signature 317 328 3.9E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00385 P450 superfamily signature 205 222 3.9E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 PRINTS PR00385 P450 superfamily signature 240 251 3.9E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 310 319 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_17105 6b06dd6ce97fd0f08551df4c9c9af530 374 SUPERFAMILY SSF48264 2 368 9.69E-86 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15350 ca1e75eb73cf4d4aee9ee594e41f479e 288 Gene3D G3DSA:3.60.20.10 76 287 2.8E-70 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_15350 ca1e75eb73cf4d4aee9ee594e41f479e 288 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 72 281 1.9E-82 T 12-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 TL08_15350 ca1e75eb73cf4d4aee9ee594e41f479e 288 Pfam PF00227 Proteasome subunit 74 253 9.4E-36 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TL08_15350 ca1e75eb73cf4d4aee9ee594e41f479e 288 SUPERFAMILY SSF56235 71 281 2.44E-49 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_15350 ca1e75eb73cf4d4aee9ee594e41f479e 288 PRINTS PR00141 Proteasome component signature 210 221 6.3E-7 T 12-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TL08_15350 ca1e75eb73cf4d4aee9ee594e41f479e 288 PRINTS PR00141 Proteasome component signature 221 232 6.3E-7 T 12-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TL08_15350 ca1e75eb73cf4d4aee9ee594e41f479e 288 PRINTS PR00141 Proteasome component signature 83 98 6.3E-7 T 12-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TL08_21110 e7ef3505c550ddbee6da4a0e0a150fb8 305 SUPERFAMILY SSF53448 28 208 8.34E-28 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_21110 e7ef3505c550ddbee6da4a0e0a150fb8 305 Gene3D G3DSA:3.90.550.10 10 240 3.7E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_21110 e7ef3505c550ddbee6da4a0e0a150fb8 305 Pfam PF00535 Glycosyl transferase family 2 29 131 8.2E-10 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_06870 3938284f30c43c8fdc61298b6e514a07 678 Gene3D G3DSA:2.70.98.10 39 283 3.2E-71 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TL08_06870 3938284f30c43c8fdc61298b6e514a07 678 Pfam PF10566 Glycoside hydrolase 97 295 576 3.9E-91 T 12-10-2018 IPR019563 Glycosyl-hydrolase 97, catalytic domain TL08_06870 3938284f30c43c8fdc61298b6e514a07 678 Pfam PF14508 Glycosyl-hydrolase 97 N-terminal 41 290 5.9E-64 T 12-10-2018 IPR029486 Glycosyl-hydrolase 97, N-terminal domain TL08_06870 3938284f30c43c8fdc61298b6e514a07 678 Pfam PF14509 Glycosyl-hydrolase 97 C-terminal, oligomerisation 579 675 1.9E-26 T 12-10-2018 IPR029483 Glycosyl-hydrolase 97, C-terminal oligomerisation domain TL08_06870 3938284f30c43c8fdc61298b6e514a07 678 Gene3D G3DSA:3.20.20.70 287 678 2.0E-142 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_06870 3938284f30c43c8fdc61298b6e514a07 678 SUPERFAMILY SSF51445 324 560 1.54E-9 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 295 7.9E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 Gene3D G3DSA:1.10.287.130 182 295 4.4E-20 T 12-10-2018 TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 Gene3D G3DSA:3.30.565.10 301 444 8.4E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 SUPERFAMILY SSF47384 213 296 7.26E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 SUPERFAMILY SSF55874 285 442 3.8E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 442 9.1E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 SMART SM00388 230 295 1.7E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 SMART SM00387 335 444 4.6E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 442 1.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 1.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 1.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_04410 e8f8a250e05a371adc71c2dcbc9130ea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 398 1.1E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 SUPERFAMILY SSF50494 201 376 1.51E-34 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 SUPERFAMILY SSF54806 132 189 3.4E-5 T 12-10-2018 IPR037295 Alpha-lytic protease prodomain TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 PIRSF PIRSF001134 1 383 2.2E-127 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 Pfam PF00089 Trypsin 200 372 5.5E-9 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 331 342 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 282 302 1.3E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 322 345 1.3E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 222 236 1.3E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 303 320 1.3E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 346 360 1.3E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 Pfam PF02983 Alpha-lytic protease prodomain 125 182 1.5E-9 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 Gene3D G3DSA:2.40.10.10 202 379 1.8E-71 T 12-10-2018 TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 Gene3D G3DSA:3.30.300.50 41 120 2.4E-8 T 12-10-2018 IPR035070 Streptogrisin prodomain TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 Gene3D G3DSA:3.30.300.50 121 192 9.2E-8 T 12-10-2018 IPR035070 Streptogrisin prodomain TL08_02110 f2b9f45f36b4c98e09c3d9b5fd1b1c94 383 Gene3D G3DSA:2.40.10.10 270 368 1.8E-71 T 12-10-2018 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 SUPERFAMILY SSF140490 333 426 8.11E-34 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 348 359 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 SUPERFAMILY SSF142019 12 246 5.36E-88 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 SMART SM00928 335 380 1.9E-23 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 Pfam PF10531 SLBB domain 251 296 5.9E-11 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 Gene3D G3DSA:3.40.50.11540 60 238 9.4E-79 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 55 226 1.1E-46 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 Gene3D G3DSA:3.10.20.600 239 332 1.7E-29 T 12-10-2018 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 339 418 7.2E-31 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 SUPERFAMILY SSF142984 248 330 1.12E-22 T 12-10-2018 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 16 418 2.9E-187 T 12-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 174 189 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02630 01ff5a85518256f26d50ca8597c43785 441 Gene3D G3DSA:1.20.1440.230 334 432 1.2E-31 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 SUPERFAMILY SSF55424 333 457 1.08E-29 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 Gene3D G3DSA:3.30.390.30 336 458 4.0E-33 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 Gene3D G3DSA:3.50.50.60 144 261 1.1E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 2.1E-69 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.1E-69 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 2.1E-69 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 2.1E-69 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 2.1E-69 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 2.1E-69 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 2.1E-69 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 2.1E-69 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 2.1E-69 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 317 5.3E-74 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PIRSF PIRSF000350 2 449 3.7E-75 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 SUPERFAMILY SSF51905 3 326 9.07E-62 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 6.7E-38 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 6.7E-38 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.7E-38 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 6.7E-38 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 6.7E-38 T 12-10-2018 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 447 6.9E-25 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 457 8.1E-139 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 Gene3D G3DSA:3.50.50.60 7 322 1.1E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_21865 e1b3fe3243df7cac78e1243b01dc11d9 460 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TL08_05055 ada2146ec6ae7e2774f44d89d6885aee 464 Pfam PF00501 AMP-binding enzyme 35 381 2.7E-38 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_05055 ada2146ec6ae7e2774f44d89d6885aee 464 SUPERFAMILY SSF56801 36 455 2.09E-61 T 12-10-2018 TL08_05055 ada2146ec6ae7e2774f44d89d6885aee 464 Gene3D G3DSA:3.40.50.12780 31 374 7.6E-49 T 12-10-2018 TL08_04645 b6eb07e8adb24f34003f02b121e1b26c 234 Gene3D G3DSA:1.10.10.10 166 226 1.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04645 b6eb07e8adb24f34003f02b121e1b26c 234 Pfam PF04542 Sigma-70 region 2 70 135 3.0E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_04645 b6eb07e8adb24f34003f02b121e1b26c 234 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 66 222 4.5E-29 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_04645 b6eb07e8adb24f34003f02b121e1b26c 234 Pfam PF08281 Sigma-70, region 4 168 218 1.0E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_04645 b6eb07e8adb24f34003f02b121e1b26c 234 SUPERFAMILY SSF88659 164 223 4.67E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_04645 b6eb07e8adb24f34003f02b121e1b26c 234 Gene3D G3DSA:1.10.1740.10 57 136 2.2E-24 T 12-10-2018 TL08_04645 b6eb07e8adb24f34003f02b121e1b26c 234 SUPERFAMILY SSF88946 66 144 9.26E-24 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 Pfam PF01225 Mur ligase family, catalytic domain 32 79 4.5E-8 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 Pfam PF08245 Mur ligase middle domain 121 319 8.1E-38 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 SUPERFAMILY SSF63418 25 110 1.01E-15 T 12-10-2018 IPR035911 MurE/MurF, N-terminal TL08_09460 817a111a352323564b881c4c6b1f52a4 505 SUPERFAMILY SSF53244 339 498 3.79E-44 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 30 496 3.5E-136 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 423 1.2E-18 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 Gene3D G3DSA:3.40.1190.10 112 340 1.7E-76 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 7 496 31.644 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 Gene3D G3DSA:3.40.1390.10 4 111 2.0E-29 T 12-10-2018 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 SUPERFAMILY SSF53623 112 337 8.9E-63 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_09460 817a111a352323564b881c4c6b1f52a4 505 Gene3D G3DSA:3.90.190.20 341 501 1.7E-52 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_12840 43f1cbe450ba84784325495f30e7127a 187 Pfam PF04542 Sigma-70 region 2 22 89 7.9E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_12840 43f1cbe450ba84784325495f30e7127a 187 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 13 168 5.9E-49 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 TL08_12840 43f1cbe450ba84784325495f30e7127a 187 Pfam PF08281 Sigma-70, region 4 111 163 8.8E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_12840 43f1cbe450ba84784325495f30e7127a 187 Gene3D G3DSA:1.10.1740.10 8 89 3.1E-11 T 12-10-2018 TL08_12840 43f1cbe450ba84784325495f30e7127a 187 SUPERFAMILY SSF88659 110 168 4.67E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_12840 43f1cbe450ba84784325495f30e7127a 187 SUPERFAMILY SSF88946 12 101 3.14E-16 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_12840 43f1cbe450ba84784325495f30e7127a 187 Gene3D G3DSA:1.10.10.10 90 169 3.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12840 43f1cbe450ba84784325495f30e7127a 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 167 5.0E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_09610 8658d7f0b3c6b6b653f94f78a99e0d98 435 Gene3D G3DSA:3.90.1150.10 14 424 6.7E-154 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_09610 8658d7f0b3c6b6b653f94f78a99e0d98 435 Gene3D G3DSA:3.40.640.10 70 341 6.7E-154 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_09610 8658d7f0b3c6b6b653f94f78a99e0d98 435 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 18 431 5.3E-161 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 TL08_09610 8658d7f0b3c6b6b653f94f78a99e0d98 435 Pfam PF00202 Aminotransferase class-III 33 431 9.3E-110 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_09610 8658d7f0b3c6b6b653f94f78a99e0d98 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 253 290 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_09610 8658d7f0b3c6b6b653f94f78a99e0d98 435 SUPERFAMILY SSF53383 9 431 9.82E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 Gene3D G3DSA:3.40.50.2300 1 99 8.7E-15 T 12-10-2018 TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.4E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.4E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.4E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 SMART SM00421 148 211 1.1E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 SMART SM00448 1 120 2.2E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 195 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 Gene3D G3DSA:1.10.10.10 103 214 1.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 SUPERFAMILY SSF52172 1 179 3.44E-19 T 12-10-2018 IPR011006 CheY-like superfamily TL08_05130 bcbfd572d2c8120bff27cb94656487e1 214 Pfam PF00072 Response regulator receiver domain 3 108 1.0E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 Gene3D G3DSA:3.30.1490.20 120 182 2.3E-11 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 411 38.637 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 323 408 6.0E-25 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 SUPERFAMILY SSF51246 321 410 4.47E-22 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 SMART SM01210 322 411 2.8E-34 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 2.5E-28 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 SMART SM01209 101 287 5.3E-107 T 12-10-2018 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 Gene3D G3DSA:3.40.50.20 2 93 2.1E-30 T 12-10-2018 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 287 2.8E-65 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 12-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 SUPERFAMILY SSF52440 2 101 1.12E-29 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_26150 ad468b9f1d2693d37d3577756c516101 423 SUPERFAMILY SSF56059 102 312 2.23E-49 T 12-10-2018 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 Gene3D G3DSA:3.30.470.20 183 319 1.1E-50 T 12-10-2018 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 Gene3D G3DSA:3.90.600.10 322 408 8.4E-25 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26150 ad468b9f1d2693d37d3577756c516101 423 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 410 2.9E-143 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_23985 64d44e54b69cdbe56c0d31735c65b025 117 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 103 2.8E-21 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TL08_23985 64d44e54b69cdbe56c0d31735c65b025 117 Pfam PF03334 Na+/H+ antiporter subunit 11 89 8.6E-24 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TL08_13620 bed6ed857a7f187adae05fb3b4749d7a 207 SUPERFAMILY SSF52218 3 179 4.54E-26 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_13620 bed6ed857a7f187adae05fb3b4749d7a 207 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 6 201 5.9E-87 T 12-10-2018 IPR023932 Uncharacterised protein family, CE1759 TL08_13620 bed6ed857a7f187adae05fb3b4749d7a 207 Gene3D G3DSA:3.40.50.360 1 182 1.9E-47 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_13620 bed6ed857a7f187adae05fb3b4749d7a 207 Pfam PF03358 NADPH-dependent FMN reductase 5 156 3.9E-35 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 Pfam PF16921 Tex protein YqgF-like domain 349 474 3.1E-50 T 12-10-2018 IPR032639 Tex protein, YqgF-like domain TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 SUPERFAMILY SSF158832 14 343 6.41E-113 T 12-10-2018 TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 SUPERFAMILY SSF47781 583 654 6.67E-18 T 12-10-2018 IPR010994 RuvA domain 2-like TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 Gene3D G3DSA:2.40.50.140 654 746 1.4E-25 T 12-10-2018 TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 Pfam PF00575 S1 RNA binding domain 672 743 1.3E-18 T 12-10-2018 IPR003029 S1 domain GO:0003676 TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 SUPERFAMILY SSF53098 344 492 6.83E-50 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 SMART SM00316 672 743 1.8E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 SMART SM00732 348 447 4.7E-39 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 Pfam PF09371 Tex-like protein N-terminal domain 22 205 6.9E-67 T 12-10-2018 IPR018974 Tex-like protein, N-terminal TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 Gene3D G3DSA:1.10.3500.10 125 521 6.3E-149 T 12-10-2018 IPR023323 Tex-like domain superfamily TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 Gene3D G3DSA:3.30.420.140 347 474 6.3E-149 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 Gene3D G3DSA:1.10.150.310 522 653 3.8E-47 T 12-10-2018 TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 SUPERFAMILY SSF50249 661 749 5.45E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 Gene3D G3DSA:1.10.10.650 12 122 1.4E-38 T 12-10-2018 IPR023319 Tex-like protein, HTH domain superfamily TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 Pfam PF12836 Helix-hairpin-helix motif 514 578 5.3E-28 T 12-10-2018 TL08_20180 66e22e4d0aff8edccdd43724955cafbd 825 SUPERFAMILY SSF47781 493 581 7.34E-27 T 12-10-2018 IPR010994 RuvA domain 2-like TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 Gene3D G3DSA:3.40.50.1000 346 613 3.5E-89 T 12-10-2018 IPR023214 HAD superfamily TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 365 379 7.1E-29 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 583 7.1E-29 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 216 230 7.1E-29 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 489 500 7.1E-29 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 511 521 7.1E-29 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 587 599 7.1E-29 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 367 373 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 84 673 1.8E-168 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 SUPERFAMILY SSF56784 364 669 4.36E-58 T 12-10-2018 IPR036412 HAD-like superfamily TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 Pfam PF00122 E1-E2 ATPase 166 344 2.5E-46 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 Pfam PF00702 haloacid dehalogenase-like hydrolase 361 577 1.1E-45 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 Gene3D G3DSA:2.70.150.20 159 271 1.6E-33 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 SUPERFAMILY SSF81665 113 357 4.05E-12 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 138 642 9.1E-81 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 Gene3D G3DSA:3.40.1110.10 376 496 3.5E-89 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 SUPERFAMILY SSF81653 174 266 4.84E-23 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00943 Copper-transporting ATPase signature 87 106 2.2E-8 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00943 Copper-transporting ATPase signature 637 651 2.2E-8 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00943 Copper-transporting ATPase signature 289 303 2.2E-8 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00943 Copper-transporting ATPase signature 348 363 2.2E-8 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00943 Copper-transporting ATPase signature 155 173 2.2E-8 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 PRINTS PR00943 Copper-transporting ATPase signature 541 558 2.2E-8 T 12-10-2018 TL08_05975 6d90c64fa0c650eb4833109e0ab9600a 681 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 102 671 8.5E-173 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TL08_05230 2d9829acb29daae9729908f6dc517d35 278 Pfam PF02517 CAAX protease self-immunity 121 210 1.4E-17 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TL08_14245 8d47225a726501e1cfa3111f7cc1edbd 338 SMART SM00342 238 321 3.7E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_14245 8d47225a726501e1cfa3111f7cc1edbd 338 Gene3D G3DSA:1.10.10.60 224 326 3.4E-25 T 12-10-2018 TL08_14245 8d47225a726501e1cfa3111f7cc1edbd 338 SUPERFAMILY SSF52317 10 203 2.0E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_14245 8d47225a726501e1cfa3111f7cc1edbd 338 Pfam PF12833 Helix-turn-helix domain 244 322 1.4E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_14245 8d47225a726501e1cfa3111f7cc1edbd 338 SUPERFAMILY SSF46689 227 271 6.27E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14245 8d47225a726501e1cfa3111f7cc1edbd 338 Gene3D G3DSA:3.40.50.880 7 215 2.0E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_14245 8d47225a726501e1cfa3111f7cc1edbd 338 SUPERFAMILY SSF46689 275 325 1.39E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14245 8d47225a726501e1cfa3111f7cc1edbd 338 Pfam PF01965 DJ-1/PfpI family 10 181 9.9E-13 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TL08_21750 36a73df4a06d8a0613bc7d1dfd253987 374 SUPERFAMILY SSF50022 289 372 1.44E-24 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_21750 36a73df4a06d8a0613bc7d1dfd253987 374 Pfam PF00355 Rieske [2Fe-2S] domain 263 346 6.2E-11 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TL08_21750 36a73df4a06d8a0613bc7d1dfd253987 374 Gene3D G3DSA:2.102.10.10 207 370 3.2E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_04125 741f25262fb576e24e3cfa0f369b09f4 472 Gene3D G3DSA:3.40.50.300 260 467 2.2E-52 T 12-10-2018 TL08_04125 741f25262fb576e24e3cfa0f369b09f4 472 SUPERFAMILY SSF52540 201 422 3.26E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04125 741f25262fb576e24e3cfa0f369b09f4 472 SMART SM00670 45 172 7.0E-20 T 12-10-2018 IPR002716 PIN domain TL08_04125 741f25262fb576e24e3cfa0f369b09f4 472 Gene3D G3DSA:3.40.50.1010 40 187 2.9E-18 T 12-10-2018 TL08_04125 741f25262fb576e24e3cfa0f369b09f4 472 Pfam PF02562 PhoH-like protein 262 466 3.5E-53 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 TL08_04125 741f25262fb576e24e3cfa0f369b09f4 472 Pfam PF13638 PIN domain 47 185 1.9E-27 T 12-10-2018 IPR002716 PIN domain TL08_04125 741f25262fb576e24e3cfa0f369b09f4 472 SUPERFAMILY SSF88723 46 179 3.58E-9 T 12-10-2018 IPR029060 PIN-like domain superfamily TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 Gene3D G3DSA:3.40.50.1380 8 210 5.5E-83 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 PIRSF PIRSF000414 10 533 6.3E-188 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 SUPERFAMILY SSF52335 16 205 1.57E-63 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 Pfam PF01808 AICARFT/IMPCHase bienzyme 148 467 3.7E-108 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 Gene3D G3DSA:3.40.140.20 405 533 7.5E-49 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 16 533 40.268 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 SMART SM00798 147 468 7.0E-164 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 SUPERFAMILY SSF53927 225 533 7.62E-110 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 17 533 2.7E-161 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 Gene3D G3DSA:3.40.140.20 222 382 6.5E-54 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 Pfam PF02142 MGS-like domain 29 141 2.6E-24 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain TL08_24570 3030ddc8d6fe9bf0760fb8aae9fa690e 533 SMART SM00851 28 142 1.6E-45 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 SUPERFAMILY SSF52540 59 288 1.31E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 Pfam PF00196 Bacterial regulatory proteins, luxR family 906 957 1.3E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 SUPERFAMILY SSF46894 898 960 3.4E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 SUPERFAMILY SSF48452 645 785 4.55E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 Gene3D G3DSA:3.40.50.300 53 223 1.9E-7 T 12-10-2018 TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 907 921 6.3E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 937 949 6.3E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 921 937 6.3E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 Pfam PF13191 AAA ATPase domain 64 221 3.6E-17 T 12-10-2018 TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 Gene3D G3DSA:1.25.40.10 626 817 4.1E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 Gene3D G3DSA:1.10.10.10 878 961 2.8E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_14525 047de8a161ebea9ab5c773b8117b66f4 966 SMART SM00421 904 961 3.6E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_22755 bc9f76c56525a4047bdeb6f016a49072 287 Pfam PF13560 Helix-turn-helix domain 12 74 1.3E-10 T 12-10-2018 TL08_22755 bc9f76c56525a4047bdeb6f016a49072 287 SMART SM00530 16 71 1.3E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_22755 bc9f76c56525a4047bdeb6f016a49072 287 SUPERFAMILY SSF47413 10 70 2.22E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_22755 bc9f76c56525a4047bdeb6f016a49072 287 Gene3D G3DSA:1.10.260.40 11 80 5.6E-8 T 12-10-2018 TL08_22225 bfdcf2cc75e3652313a7bf59df1470cb 412 Gene3D G3DSA:3.40.47.10 1 255 2.1E-75 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_22225 bfdcf2cc75e3652313a7bf59df1470cb 412 SMART SM00825 Beta-ketoacyl synthase 6 399 2.4E-14 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_22225 bfdcf2cc75e3652313a7bf59df1470cb 412 SUPERFAMILY SSF53901 5 251 1.47E-64 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_22225 bfdcf2cc75e3652313a7bf59df1470cb 412 Gene3D G3DSA:3.40.47.10 259 407 2.7E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_22225 bfdcf2cc75e3652313a7bf59df1470cb 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_22225 bfdcf2cc75e3652313a7bf59df1470cb 412 SUPERFAMILY SSF53901 214 407 2.77E-63 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_22225 bfdcf2cc75e3652313a7bf59df1470cb 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 365 9.2E-32 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_22225 bfdcf2cc75e3652313a7bf59df1470cb 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 245 1.2E-54 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 405 4.7E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 282 6.3E-84 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Gene3D G3DSA:1.10.1200.10 1479 1573 1.0E-27 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SUPERFAMILY SSF47336 1492 1577 2.09E-17 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SUPERFAMILY SSF55048 683 748 1.57E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 408 513 2.1E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Pfam PF08990 Erythronolide synthase docking 2 27 4.9E-5 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Pfam PF00550 Phosphopantetheine attachment site 1504 1568 3.8E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Gene3D G3DSA:3.40.366.10 557 865 5.2E-153 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Pfam PF00698 Acyl transferase domain 557 879 4.9E-83 T 12-10-2018 IPR014043 Acyl transferase TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 559 862 1.8E-105 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SUPERFAMILY SSF51735 1200 1320 1.81E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SMART SM00823 Phosphopantetheine attachment site 1500 1572 2.8E-22 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SMART SM00826 927 1088 1.3E-62 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SMART SM01294 1501 1568 8.8E-4 T 12-10-2018 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SUPERFAMILY SSF53901 30 395 4.99E-94 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Gene3D G3DSA:3.40.47.10 16 458 2.5E-170 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SMART SM00825 Beta-ketoacyl synthase 36 458 2.8E-191 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Gene3D G3DSA:3.30.70.3290 472 908 5.2E-153 T 12-10-2018 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 SUPERFAMILY SSF52151 556 841 7.85E-65 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Gene3D G3DSA:3.10.129.110 916 1198 2.3E-86 T 12-10-2018 TL08_14645 7fb94f5360466705ea4e80640564e82b 1644 Pfam PF14765 Polyketide synthase dehydratase 927 1195 2.0E-47 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Gene3D G3DSA:2.60.40.10 794 876 1.4E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Pfam PF06439 Domain of Unknown Function (DUF1080) 1141 1320 2.7E-36 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 SMART SM00606 983 1116 1.2E-26 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Gene3D G3DSA:2.120.10.30 328 793 6.6E-68 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 SUPERFAMILY SSF49785 990 1114 2.38E-20 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 SUPERFAMILY SSF52317 101 317 1.69E-46 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Pfam PF03422 Carbohydrate binding module (family 6) 991 1115 2.5E-24 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 SUPERFAMILY SSF49299 790 878 8.89E-18 T 12-10-2018 IPR035986 PKD domain superfamily TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Gene3D G3DSA:2.60.120.560 1134 1318 2.8E-39 T 12-10-2018 TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Pfam PF00801 PKD domain 804 867 3.1E-11 T 12-10-2018 IPR000601 PKD domain TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 SUPERFAMILY SSF50952 336 770 2.48E-21 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 SMART SM00089 793 879 2.1E-19 T 12-10-2018 IPR022409 PKD/Chitinase domain TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Pfam PF06283 Trehalose utilisation 103 312 9.1E-85 T 12-10-2018 IPR029010 ThuA-like domain TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Gene3D G3DSA:2.60.40.10 1422 1505 7.9E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Gene3D G3DSA:2.60.120.260 981 1115 1.1E-28 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Pfam PF07995 Glucose / Sorbosone dehydrogenase 354 626 1.4E-34 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Gene3D G3DSA:3.40.50.880 89 321 1.9E-90 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_23880 3b1e91626549a6cef7c6849506db8840 1685 Gene3D G3DSA:2.60.40.10 1319 1420 5.6E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_17235 3fa9ab1a6e7f1db5e0aaafb0d7bff619 140 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 93 109 8.8E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_17235 3fa9ab1a6e7f1db5e0aaafb0d7bff619 140 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 78 93 8.8E-7 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_17235 3fa9ab1a6e7f1db5e0aaafb0d7bff619 140 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 63 105 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TL08_17235 3fa9ab1a6e7f1db5e0aaafb0d7bff619 140 Gene3D G3DSA:1.10.10.60 6 63 2.1E-12 T 12-10-2018 TL08_17235 3fa9ab1a6e7f1db5e0aaafb0d7bff619 140 Gene3D G3DSA:1.10.10.60 64 115 7.1E-17 T 12-10-2018 TL08_17235 3fa9ab1a6e7f1db5e0aaafb0d7bff619 140 Pfam PF12833 Helix-turn-helix domain 32 111 2.8E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_17235 3fa9ab1a6e7f1db5e0aaafb0d7bff619 140 SUPERFAMILY SSF46689 9 60 6.27E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_17235 3fa9ab1a6e7f1db5e0aaafb0d7bff619 140 SMART SM00342 26 109 2.9E-32 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_17235 3fa9ab1a6e7f1db5e0aaafb0d7bff619 140 SUPERFAMILY SSF46689 62 114 1.79E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_19495 e646996eede185d13327c690e4696080 286 SMART SM00346 32 123 3.0E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_19495 e646996eede185d13327c690e4696080 286 Pfam PF01614 Bacterial transcriptional regulator 151 272 6.8E-30 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_19495 e646996eede185d13327c690e4696080 286 SUPERFAMILY SSF46785 32 105 5.54E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_19495 e646996eede185d13327c690e4696080 286 SUPERFAMILY SSF55781 101 273 2.49E-44 T 12-10-2018 TL08_19495 e646996eede185d13327c690e4696080 286 Gene3D G3DSA:1.10.10.10 29 100 1.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19495 e646996eede185d13327c690e4696080 286 Gene3D G3DSA:3.30.450.40 101 281 4.4E-49 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_19495 e646996eede185d13327c690e4696080 286 Pfam PF09339 IclR helix-turn-helix domain 34 85 1.1E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_15620 81ce787b1a767a6ad205043b9b284c27 199 SUPERFAMILY SSF46689 5 78 2.89E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_15620 81ce787b1a767a6ad205043b9b284c27 199 Gene3D G3DSA:1.10.357.10 57 190 3.7E-19 T 12-10-2018 TL08_15620 81ce787b1a767a6ad205043b9b284c27 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 7.4E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15620 81ce787b1a767a6ad205043b9b284c27 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_15620 81ce787b1a767a6ad205043b9b284c27 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15620 81ce787b1a767a6ad205043b9b284c27 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15620 81ce787b1a767a6ad205043b9b284c27 199 Gene3D G3DSA:1.10.10.60 5 56 2.0E-20 T 12-10-2018 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 Gene3D G3DSA:2.102.10.10 35 159 2.1E-35 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 SUPERFAMILY SSF50022 12 150 1.19E-43 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 Gene3D G3DSA:3.90.380.10 224 375 8.2E-31 T 12-10-2018 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 SUPERFAMILY SSF55961 173 371 9.42E-41 T 12-10-2018 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 179 371 2.0E-42 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 Pfam PF00355 Rieske [2Fe-2S] domain 37 122 1.6E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 72 92 2.7E-26 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 135 161 2.7E-26 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 2.7E-26 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 179 201 2.7E-26 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 51 66 2.7E-26 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TL08_06785 1c26b7f18d4b30753d88a3f7d5f7c95d 376 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 21 46 2.7E-26 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TL08_23605 ee4c631f4863645e9ffb510740b58da3 286 Gene3D G3DSA:2.30.30.100 236 284 2.6E-16 T 12-10-2018 TL08_23605 ee4c631f4863645e9ffb510740b58da3 286 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 30 282 1.2E-37 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_23605 ee4c631f4863645e9ffb510740b58da3 286 Pfam PF02237 Biotin protein ligase C terminal domain 235 282 5.9E-9 T 12-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_23605 ee4c631f4863645e9ffb510740b58da3 286 SUPERFAMILY SSF55681 28 221 1.99E-44 T 12-10-2018 TL08_23605 ee4c631f4863645e9ffb510740b58da3 286 SUPERFAMILY SSF50037 239 282 1.01E-5 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal TL08_23605 ee4c631f4863645e9ffb510740b58da3 286 Gene3D G3DSA:3.30.930.10 1 231 3.2E-63 T 12-10-2018 TL08_23605 ee4c631f4863645e9ffb510740b58da3 286 Pfam PF03099 Biotin/lipoate A/B protein ligase family 51 164 3.1E-10 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TL08_18090 be38c79f0e99e2b59421bda9dbe37126 225 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 15 208 5.4E-53 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TL08_18090 be38c79f0e99e2b59421bda9dbe37126 225 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 20 204 1.2E-58 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TL08_18090 be38c79f0e99e2b59421bda9dbe37126 225 SUPERFAMILY SSF50486 14 214 1.65E-57 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 TL08_18090 be38c79f0e99e2b59421bda9dbe37126 225 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 14 208 30.091 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TL08_18090 be38c79f0e99e2b59421bda9dbe37126 225 Gene3D G3DSA:3.10.300.10 12 218 1.8E-59 T 12-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TL08_06345 0a8e6158239b5cdd122771f4a15e6a42 116 SUPERFAMILY SSF143120 5 47 1.01E-6 T 12-10-2018 IPR036165 YefM-like superfamily TL08_06345 0a8e6158239b5cdd122771f4a15e6a42 116 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 48 6.0E-7 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TL08_06345 0a8e6158239b5cdd122771f4a15e6a42 116 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 49 4.3E-8 T 12-10-2018 TL08_24825 261990dab65b700001970fa0761a85fa 180 SUPERFAMILY SSF55729 1 153 4.97E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_24825 261990dab65b700001970fa0761a85fa 180 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 69 163 7.0E-27 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 TL08_24825 261990dab65b700001970fa0761a85fa 180 Pfam PF00583 Acetyltransferase (GNAT) family 61 143 2.3E-18 T 12-10-2018 IPR000182 GNAT domain TL08_24825 261990dab65b700001970fa0761a85fa 180 Gene3D G3DSA:3.40.630.30 5 179 1.9E-38 T 12-10-2018 TL08_18620 007bfaad2af1a71c3d87a9f34ad73289 278 PRINTS PR00412 Epoxide hydrolase signature 47 62 3.3E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_18620 007bfaad2af1a71c3d87a9f34ad73289 278 PRINTS PR00412 Epoxide hydrolase signature 27 45 3.3E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_18620 007bfaad2af1a71c3d87a9f34ad73289 278 PRINTS PR00412 Epoxide hydrolase signature 104 117 3.3E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_18620 007bfaad2af1a71c3d87a9f34ad73289 278 PRINTS PR00412 Epoxide hydrolase signature 248 270 3.3E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_18620 007bfaad2af1a71c3d87a9f34ad73289 278 Pfam PF12697 Alpha/beta hydrolase family 23 263 1.2E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_18620 007bfaad2af1a71c3d87a9f34ad73289 278 SUPERFAMILY SSF53474 4 273 2.58E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18620 007bfaad2af1a71c3d87a9f34ad73289 278 Gene3D G3DSA:3.40.50.1820 2 271 3.7E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_19315 6bd88ba403b2d3862403c609246a2804 257 SUPERFAMILY SSF53335 55 228 6.54E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_19315 6bd88ba403b2d3862403c609246a2804 257 Pfam PF05175 Methyltransferase small domain 79 209 5.3E-17 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TL08_19315 6bd88ba403b2d3862403c609246a2804 257 Gene3D G3DSA:3.40.50.150 40 236 3.8E-34 T 12-10-2018 TL08_19315 6bd88ba403b2d3862403c609246a2804 257 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 159 165 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TL08_14495 5b4df7c1b59b1b30f0b9f9fc28ea6d2f 318 Gene3D G3DSA:3.90.180.10 12 312 3.5E-71 T 12-10-2018 TL08_14495 5b4df7c1b59b1b30f0b9f9fc28ea6d2f 318 SUPERFAMILY SSF50129 10 138 1.05E-31 T 12-10-2018 IPR011032 GroES-like superfamily TL08_14495 5b4df7c1b59b1b30f0b9f9fc28ea6d2f 318 SUPERFAMILY SSF51735 110 244 2.26E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14495 5b4df7c1b59b1b30f0b9f9fc28ea6d2f 318 Pfam PF00107 Zinc-binding dehydrogenase 151 253 3.3E-16 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_14495 5b4df7c1b59b1b30f0b9f9fc28ea6d2f 318 Gene3D G3DSA:3.40.50.720 122 263 3.5E-71 T 12-10-2018 TL08_14495 5b4df7c1b59b1b30f0b9f9fc28ea6d2f 318 SMART SM00829 11 316 7.1E-12 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_14495 5b4df7c1b59b1b30f0b9f9fc28ea6d2f 318 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 1.1E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 4.3E-68 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.991 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 SUPERFAMILY SSF50249 2 123 1.37E-52 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 Gene3D G3DSA:2.40.50.140 1 124 1.4E-63 T 12-10-2018 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 1.7E-43 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02955 c9a8c1d78985faa83ae51d6f260e4a9e 124 PIRSF PIRSF002133 1 124 4.6E-55 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_11405 5446fec219fa92dd5813d3bc7381e8b4 164 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 80 92 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 TL08_11405 5446fec219fa92dd5813d3bc7381e8b4 164 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 16 138 3.2E-40 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 TL08_11405 5446fec219fa92dd5813d3bc7381e8b4 164 Gene3D G3DSA:2.70.70.10 4 161 4.5E-44 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_11405 5446fec219fa92dd5813d3bc7381e8b4 164 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 17 135 2.2E-31 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 TL08_11405 5446fec219fa92dd5813d3bc7381e8b4 164 SUPERFAMILY SSF51261 15 160 4.19E-38 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 SMART SM00636 52 442 5.5E-124 T 12-10-2018 IPR011583 Chitinase II GO:0008061 TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 SMART SM00495 483 528 1.9E-15 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 ProSitePatterns PS01095 Chitinases family 18 active site. 210 218 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 Pfam PF00704 Glycosyl hydrolases family 18 54 442 5.3E-84 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 SUPERFAMILY SSF51055 480 531 1.16E-14 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 SUPERFAMILY SSF54556 348 414 6.26E-12 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 Gene3D G3DSA:2.10.10.20 480 531 1.2E-17 T 12-10-2018 TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 Gene3D G3DSA:3.20.20.80 55 451 6.8E-146 T 12-10-2018 TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 Gene3D G3DSA:3.10.50.10 356 423 6.8E-146 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily TL08_24055 92e09430ddd36ea0eb7b899684c5c475 531 SUPERFAMILY SSF51445 49 449 6.77E-91 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_19715 cf87f2842bf4c2b025e1bb3def19318f 318 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 141 311 1.4E-17 T 12-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain TL08_19715 cf87f2842bf4c2b025e1bb3def19318f 318 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 77 311 3.7E-33 T 12-10-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain TL08_24905 6cecc7598d05b10e76d42c4050b8580d 1008 SUPERFAMILY SSF140453 178 255 1.57E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_24905 6cecc7598d05b10e76d42c4050b8580d 1008 Gene3D G3DSA:1.10.287.1060 175 267 1.4E-6 T 12-10-2018 TL08_11165 bbf6d0635179b46b3e09dd43bf35520c 230 SMART SM00345 7 66 2.0E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_11165 bbf6d0635179b46b3e09dd43bf35520c 230 SUPERFAMILY SSF48008 88 221 5.49E-29 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_11165 bbf6d0635179b46b3e09dd43bf35520c 230 Gene3D G3DSA:1.20.120.530 88 226 4.4E-32 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_11165 bbf6d0635179b46b3e09dd43bf35520c 230 Pfam PF07729 FCD domain 92 213 1.0E-28 T 12-10-2018 IPR011711 GntR, C-terminal TL08_11165 bbf6d0635179b46b3e09dd43bf35520c 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.1E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_11165 bbf6d0635179b46b3e09dd43bf35520c 230 Gene3D G3DSA:1.10.10.10 2 70 1.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11165 bbf6d0635179b46b3e09dd43bf35520c 230 SUPERFAMILY SSF46785 2 70 1.04E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_11165 bbf6d0635179b46b3e09dd43bf35520c 230 SMART SM00895 92 214 3.3E-22 T 12-10-2018 IPR011711 GntR, C-terminal TL08_00555 fcfb4fdb9f245e1383075440b256df59 232 SUPERFAMILY SSF55781 87 232 7.19E-17 T 12-10-2018 TL08_00555 fcfb4fdb9f245e1383075440b256df59 232 SUPERFAMILY SSF46785 31 100 6.15E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_00555 fcfb4fdb9f245e1383075440b256df59 232 Pfam PF09339 IclR helix-turn-helix domain 31 83 8.1E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_00555 fcfb4fdb9f245e1383075440b256df59 232 Gene3D G3DSA:3.30.450.40 171 232 4.4E-5 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_00555 fcfb4fdb9f245e1383075440b256df59 232 Gene3D G3DSA:3.30.450.40 101 169 6.8E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_00555 fcfb4fdb9f245e1383075440b256df59 232 Gene3D G3DSA:1.10.10.10 24 98 3.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_00555 fcfb4fdb9f245e1383075440b256df59 232 SMART SM00346 29 116 1.2E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_17900 2d1cb97b65c75bcd3237f1a5aea60b94 259 Gene3D G3DSA:3.40.50.300 4 254 3.3E-65 T 12-10-2018 TL08_17900 2d1cb97b65c75bcd3237f1a5aea60b94 259 SUPERFAMILY SSF52540 4 232 1.3E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17900 2d1cb97b65c75bcd3237f1a5aea60b94 259 Pfam PF00005 ABC transporter 21 167 2.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_17900 2d1cb97b65c75bcd3237f1a5aea60b94 259 SMART SM00382 29 217 1.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17900 2d1cb97b65c75bcd3237f1a5aea60b94 259 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_25265 17e6ef5765c81bee78c9f11559ee9ca0 352 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 41 52 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25265 17e6ef5765c81bee78c9f11559ee9ca0 352 Gene3D G3DSA:3.20.20.70 23 352 2.2E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_25265 17e6ef5765c81bee78c9f11559ee9ca0 352 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 26 352 2.2E-112 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25265 17e6ef5765c81bee78c9f11559ee9ca0 352 Pfam PF13353 4Fe-4S single cluster domain 42 128 4.5E-7 T 12-10-2018 TL08_25265 17e6ef5765c81bee78c9f11559ee9ca0 352 Pfam PF04055 Radical SAM superfamily 41 201 4.4E-30 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_25265 17e6ef5765c81bee78c9f11559ee9ca0 352 Pfam PF06463 Molybdenum Cofactor Synthesis C 208 334 8.8E-38 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25265 17e6ef5765c81bee78c9f11559ee9ca0 352 SMART SM00729 35 237 4.1E-10 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_25265 17e6ef5765c81bee78c9f11559ee9ca0 352 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 26 352 40.345 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25265 17e6ef5765c81bee78c9f11559ee9ca0 352 SUPERFAMILY SSF102114 25 323 6.02E-74 T 12-10-2018 TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 Gene3D G3DSA:3.40.50.300 23 478 1.9E-138 T 12-10-2018 TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 SUPERFAMILY SSF52540 26 466 1.37E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 Gene3D G3DSA:3.40.50.300 505 822 6.4E-109 T 12-10-2018 TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 Gene3D G3DSA:1.10.8.280 169 291 1.9E-138 T 12-10-2018 TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 Gene3D G3DSA:1.20.1580.10 577 716 6.4E-109 T 12-10-2018 TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 Pfam PF00005 ABC transporter 522 749 3.8E-8 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 Gene3D G3DSA:1.20.1580.10 108 376 1.9E-138 T 12-10-2018 TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 ProSitePatterns PS00211 ABC transporters family signature. 716 730 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 SUPERFAMILY SSF52540 518 797 2.23E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 SMART SM00382 40 451 1.3 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_05360 ed1614bc7d909ddd0974cccd789fa5ed 841 SMART SM00382 521 832 1.2E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 6.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 6.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 6.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 SUPERFAMILY SSF46894 149 221 6.8E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 Gene3D G3DSA:3.40.50.12740 15 221 8.1E-68 T 12-10-2018 TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 SMART SM00448 15 129 4.0E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 214 9.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 SUPERFAMILY SSF52172 15 136 5.41E-30 T 12-10-2018 IPR011006 CheY-like superfamily TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 Pfam PF00072 Response regulator receiver domain 17 129 7.4E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 SMART SM00421 158 215 1.9E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_09040 0d1d42d8ae9ac3090bcf17b9a9ba2447 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 Pfam PF04539 Sigma-70 region 3 124 188 3.8E-10 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 36 252 1.5E-78 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 SUPERFAMILY SSF88946 18 110 4.32E-27 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 SUPERFAMILY SSF88659 179 254 2.24E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 Gene3D G3DSA:1.10.10.10 175 256 2.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 Pfam PF04545 Sigma-70, region 4 202 250 1.3E-14 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 SUPERFAMILY SSF88659 114 183 8.72E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 PRINTS PR00046 Major sigma-70 factor signature 65 78 2.0E-8 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 PRINTS PR00046 Major sigma-70 factor signature 206 218 2.0E-8 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 PRINTS PR00046 Major sigma-70 factor signature 238 249 2.0E-8 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 PRINTS PR00046 Major sigma-70 factor signature 223 238 2.0E-8 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 251 1.0E-33 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 Pfam PF04542 Sigma-70 region 2 41 110 5.9E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 Gene3D G3DSA:1.20.120.1810 3 109 2.0E-18 T 12-10-2018 TL08_20300 a43fbdb6f986991b2ff14db5dc8437a4 259 Gene3D G3DSA:1.10.10.10 111 163 1.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23200 2003aa6d72058bf650fb1374add28ac7 257 Pfam PF02586 SOS response associated peptidase (SRAP) 1 229 5.4E-61 T 12-10-2018 IPR003738 SOS response associated peptidase (SRAP) TL08_23200 2003aa6d72058bf650fb1374add28ac7 257 Gene3D G3DSA:3.90.1680.10 1 241 6.2E-64 T 12-10-2018 IPR036590 SOS response associated peptidase-like TL08_23200 2003aa6d72058bf650fb1374add28ac7 257 SUPERFAMILY SSF143081 2 241 2.35E-61 T 12-10-2018 IPR036590 SOS response associated peptidase-like TL08_22960 704768824b99b7244744507b461bd925 367 Pfam PF07690 Major Facilitator Superfamily 4 330 1.6E-24 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_22960 704768824b99b7244744507b461bd925 367 Gene3D G3DSA:1.20.1250.20 1 361 1.8E-35 T 12-10-2018 TL08_22960 704768824b99b7244744507b461bd925 367 ProSitePatterns PS00217 Sugar transport proteins signature 2. 95 120 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_22960 704768824b99b7244744507b461bd925 367 SUPERFAMILY SSF103473 2 358 1.44E-38 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_00645 c9c84f95e87327fac2decf7b75761d4d 217 SUPERFAMILY SSF47413 37 105 8.04E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_00645 c9c84f95e87327fac2decf7b75761d4d 217 Pfam PF13560 Helix-turn-helix domain 41 99 4.7E-17 T 12-10-2018 TL08_00645 c9c84f95e87327fac2decf7b75761d4d 217 SUPERFAMILY SSF51182 84 211 4.46E-19 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_00645 c9c84f95e87327fac2decf7b75761d4d 217 SMART SM00530 44 99 2.7E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_00645 c9c84f95e87327fac2decf7b75761d4d 217 Pfam PF07883 Cupin domain 144 211 7.3E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TL08_00645 c9c84f95e87327fac2decf7b75761d4d 217 Gene3D G3DSA:1.10.260.40 39 110 2.6E-19 T 12-10-2018 TL08_00645 c9c84f95e87327fac2decf7b75761d4d 217 Gene3D G3DSA:2.60.120.10 111 212 8.3E-14 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_18185 b45533b6038c02a4e89e36f6bd8ffe2f 64 Pfam PF01632 Ribosomal protein L35 2 62 7.8E-24 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18185 b45533b6038c02a4e89e36f6bd8ffe2f 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_18185 b45533b6038c02a4e89e36f6bd8ffe2f 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.9E-14 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TL08_18185 b45533b6038c02a4e89e36f6bd8ffe2f 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.9E-14 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TL08_18185 b45533b6038c02a4e89e36f6bd8ffe2f 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.9E-14 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TL08_18185 b45533b6038c02a4e89e36f6bd8ffe2f 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 7.1E-23 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TL08_18185 b45533b6038c02a4e89e36f6bd8ffe2f 64 SUPERFAMILY SSF143034 2 63 6.8E-21 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18185 b45533b6038c02a4e89e36f6bd8ffe2f 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 16.876 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TL08_18185 b45533b6038c02a4e89e36f6bd8ffe2f 64 Gene3D G3DSA:2.40.50.530 1 63 1.9E-23 T 12-10-2018 TL08_11460 23b9b81992525db64baa3bb02c40774b 187 Gene3D G3DSA:2.40.50.140 128 187 3.9E-24 T 12-10-2018 TL08_11460 23b9b81992525db64baa3bb02c40774b 187 Gene3D G3DSA:2.30.30.30 1 62 4.7E-27 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 TL08_11460 23b9b81992525db64baa3bb02c40774b 187 Gene3D G3DSA:2.40.50.140 64 127 1.8E-23 T 12-10-2018 TL08_11460 23b9b81992525db64baa3bb02c40774b 187 SUPERFAMILY SSF50249 129 185 3.77E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_11460 23b9b81992525db64baa3bb02c40774b 187 SUPERFAMILY SSF50104 2 63 1.02E-19 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TL08_11460 23b9b81992525db64baa3bb02c40774b 187 SMART SM01185 67 121 4.2E-26 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TL08_11460 23b9b81992525db64baa3bb02c40774b 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 8.3E-75 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TL08_11460 23b9b81992525db64baa3bb02c40774b 187 PIRSF PIRSF005901 1 186 7.7E-65 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP TL08_11460 23b9b81992525db64baa3bb02c40774b 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 6.1E-26 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like TL08_11460 23b9b81992525db64baa3bb02c40774b 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 8.3E-24 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TL08_11460 23b9b81992525db64baa3bb02c40774b 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 119 8.2E-21 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TL08_11460 23b9b81992525db64baa3bb02c40774b 187 SMART SM00841 129 184 1.2E-29 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TL08_11460 23b9b81992525db64baa3bb02c40774b 187 SUPERFAMILY SSF50249 65 126 7.71E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_11460 23b9b81992525db64baa3bb02c40774b 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site TL08_11460 23b9b81992525db64baa3bb02c40774b 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 47.951 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 PIRSF PIRSF001348 3 605 2.4E-279 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 SUPERFAMILY SSF53795 243 604 1.92E-152 T 12-10-2018 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 267 275 - T 12-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 243 604 2.5E-167 T 12-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 SUPERFAMILY SSF68923 12 242 9.94E-99 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 605 49.884 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 Gene3D G3DSA:3.40.449.10 21 242 4.8E-273 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 22 239 3.3E-101 T 12-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 Gene3D G3DSA:3.90.228.20 243 600 4.8E-273 T 12-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TL08_26675 d142b706bff7d4b67a9df9886c75e156 605 Gene3D G3DSA:2.170.8.10 57 398 4.8E-273 T 12-10-2018 TL08_08210 6b3835b48fc55808e3f488f6145ba981 465 SUPERFAMILY SSF53720 52 462 1.19E-113 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_08210 6b3835b48fc55808e3f488f6145ba981 465 Gene3D G3DSA:3.40.605.10 66 457 5.4E-158 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_08210 6b3835b48fc55808e3f488f6145ba981 465 Gene3D G3DSA:3.40.309.10 272 420 5.4E-158 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_08210 6b3835b48fc55808e3f488f6145ba981 465 Pfam PF00171 Aldehyde dehydrogenase family 51 332 1.9E-15 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_08210 6b3835b48fc55808e3f488f6145ba981 465 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 51 462 41.194 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TL08_08210 6b3835b48fc55808e3f488f6145ba981 465 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 59 452 3.3E-143 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TL08_08210 6b3835b48fc55808e3f488f6145ba981 465 PIRSF PIRSF000151 46 463 6.1E-167 T 12-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 TL08_04315 e4cac7385937476d43ce10322ebd941e 104 Pfam PF06013 Proteins of 100 residues with WXG 5 94 3.8E-7 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like TL08_04315 e4cac7385937476d43ce10322ebd941e 104 SUPERFAMILY SSF140453 5 102 4.05E-9 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_04315 e4cac7385937476d43ce10322ebd941e 104 Gene3D G3DSA:1.10.287.1060 3 102 2.1E-15 T 12-10-2018 TL08_07020 e9e4d5b2baadb80fd4e40a88bdb917fe 443 SUPERFAMILY SSF48452 6 175 2.3E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_07020 e9e4d5b2baadb80fd4e40a88bdb917fe 443 Gene3D G3DSA:1.25.40.10 2 122 2.8E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_07020 e9e4d5b2baadb80fd4e40a88bdb917fe 443 Pfam PF12688 Tetratrico peptide repeat 8 115 2.4E-4 T 12-10-2018 TL08_07020 e9e4d5b2baadb80fd4e40a88bdb917fe 443 Gene3D G3DSA:1.25.40.10 123 201 1.3E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_07020 e9e4d5b2baadb80fd4e40a88bdb917fe 443 SMART SM00028 145 178 87.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_07020 e9e4d5b2baadb80fd4e40a88bdb917fe 443 SMART SM00028 6 39 140.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_07020 e9e4d5b2baadb80fd4e40a88bdb917fe 443 SMART SM00028 40 73 1.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_07020 e9e4d5b2baadb80fd4e40a88bdb917fe 443 SMART SM00028 74 107 51.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_07020 e9e4d5b2baadb80fd4e40a88bdb917fe 443 Pfam PF13432 Tetratricopeptide repeat 127 177 0.0053 T 12-10-2018 TL08_11705 a88ca21cd0d6b6a19fa8206eb3fd2bad 318 Gene3D G3DSA:1.10.357.140 39 192 1.1E-16 T 12-10-2018 TL08_11705 a88ca21cd0d6b6a19fa8206eb3fd2bad 318 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 29 306 3.8E-96 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TL08_11705 a88ca21cd0d6b6a19fa8206eb3fd2bad 318 Pfam PF01040 UbiA prenyltransferase family 42 290 3.4E-65 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TL08_11705 a88ca21cd0d6b6a19fa8206eb3fd2bad 318 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 26 308 19.167 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TL08_23120 4a7e6d1415b62daf396e295d11b5beba 552 SUPERFAMILY SSF53335 177 302 8.0E-12 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_23120 4a7e6d1415b62daf396e295d11b5beba 552 Gene3D G3DSA:3.40.50.150 119 327 2.1E-56 T 12-10-2018 TL08_23120 4a7e6d1415b62daf396e295d11b5beba 552 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 235 241 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TL08_23120 4a7e6d1415b62daf396e295d11b5beba 552 Pfam PF01861 Protein of unknown function DUF43 131 306 4.1E-30 T 12-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal TL08_11380 b0cb6cd55f2700d70838e97cf60fc615 287 SUPERFAMILY SSF53223 3 106 2.99E-25 T 12-10-2018 TL08_11380 b0cb6cd55f2700d70838e97cf60fc615 287 SUPERFAMILY SSF51735 107 276 7.6E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_11380 b0cb6cd55f2700d70838e97cf60fc615 287 Gene3D G3DSA:3.40.50.10860 10 267 5.5E-80 T 12-10-2018 TL08_11380 b0cb6cd55f2700d70838e97cf60fc615 287 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 7 274 2.6E-71 T 12-10-2018 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+1.1.1.25+4.2.1.10+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TL08_11380 b0cb6cd55f2700d70838e97cf60fc615 287 Gene3D G3DSA:3.40.50.720 107 252 5.5E-80 T 12-10-2018 TL08_11380 b0cb6cd55f2700d70838e97cf60fc615 287 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 11 93 9.6E-21 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 377 469 8.4E-17 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 Pfam PF00550 Phosphopantetheine attachment site 743 804 8.3E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 SMART SM00823 Phosphopantetheine attachment site 741 810 0.0049 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 Gene3D G3DSA:1.10.1200.10 726 811 6.8E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 SUPERFAMILY SSF53901 6 423 7.61E-72 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 249 1.1E-59 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 ProSitePatterns PS00012 Phosphopantetheine attachment site. 765 780 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 Gene3D G3DSA:3.40.366.10 533 650 9.5E-8 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 SUPERFAMILY SSF47336 737 807 6.67E-15 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 Gene3D G3DSA:3.40.47.10 4 495 3.6E-158 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 SMART SM00825 Beta-ketoacyl synthase 10 427 1.8E-144 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14880 5feb0ceaeeece190be84fddabbe2514f 835 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 257 373 1.7E-38 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_13790 829785c70c9175496fe819fd0adc76bf 269 Gene3D G3DSA:3.40.50.11590 137 250 1.5E-6 T 12-10-2018 TL08_13790 829785c70c9175496fe819fd0adc76bf 269 Pfam PF04016 Putative heavy-metal chelation 140 247 1.5E-10 T 12-10-2018 IPR007161 Putative heavy-metal chelation domain TL08_13790 829785c70c9175496fe819fd0adc76bf 269 SUPERFAMILY SSF159713 52 248 6.93E-19 T 12-10-2018 TL08_22730 4ad135f66fb73684846e01d4755f7b55 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 7.8E-64 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TL08_22730 4ad135f66fb73684846e01d4755f7b55 168 SUPERFAMILY SSF55021 3 76 1.17E-23 T 12-10-2018 TL08_22730 4ad135f66fb73684846e01d4755f7b55 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 4 74 3.0E-31 T 12-10-2018 TL08_22730 4ad135f66fb73684846e01d4755f7b55 168 Pfam PF01842 ACT domain 4 69 2.6E-18 T 12-10-2018 IPR002912 ACT domain TL08_22730 4ad135f66fb73684846e01d4755f7b55 168 Gene3D G3DSA:3.30.70.1150 84 164 7.5E-30 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal TL08_22730 4ad135f66fb73684846e01d4755f7b55 168 Gene3D G3DSA:3.30.70.260 1 79 3.3E-36 T 12-10-2018 TL08_22730 4ad135f66fb73684846e01d4755f7b55 168 SUPERFAMILY SSF55021 81 163 4.58E-26 T 12-10-2018 TL08_22730 4ad135f66fb73684846e01d4755f7b55 168 Pfam PF10369 Small subunit of acetolactate synthase 85 158 1.7E-28 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 7.1E-5 T 12-10-2018 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 7.1E-5 T 12-10-2018 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 SUPERFAMILY SSF56425 236 354 2.09E-40 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 Gene3D G3DSA:3.90.700.10 246 349 1.0E-158 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.7E-5 T 12-10-2018 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 1.7E-5 T 12-10-2018 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 593 2.8E-247 T 12-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 593 3.0E-280 T 12-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 Gene3D G3DSA:1.20.58.100 428 541 6.7E-33 T 12-10-2018 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 12-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 Gene3D G3DSA:3.50.50.60 7 411 1.0E-158 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 Pfam PF00890 FAD binding domain 7 400 2.4E-114 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 SUPERFAMILY SSF46977 446 593 1.83E-42 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 593 3.0E-40 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 SUPERFAMILY SSF51905 2 433 2.11E-73 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_24435 c5bb25cc31b0d012f384752946cbb643 593 PIRSF PIRSF000171 1 565 3.9E-45 T 12-10-2018 TL08_15795 bf906a441fac6db0c529ef2ad4c478b4 493 Gene3D G3DSA:3.30.300.30 390 484 3.7E-15 T 12-10-2018 TL08_15795 bf906a441fac6db0c529ef2ad4c478b4 493 Pfam PF00501 AMP-binding enzyme 50 389 7.0E-29 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_15795 bf906a441fac6db0c529ef2ad4c478b4 493 Gene3D G3DSA:3.40.50.12780 16 383 1.4E-38 T 12-10-2018 TL08_15795 bf906a441fac6db0c529ef2ad4c478b4 493 Pfam PF13193 AMP-binding enzyme C-terminal domain 399 473 1.9E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_15795 bf906a441fac6db0c529ef2ad4c478b4 493 SUPERFAMILY SSF56801 37 485 1.31E-66 T 12-10-2018 TL08_03485 8e087056fe1bae9e5d28d94a26377917 439 SUPERFAMILY SSF55874 276 414 1.01E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_03485 8e087056fe1bae9e5d28d94a26377917 439 Pfam PF07730 Histidine kinase 215 280 2.4E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_03485 8e087056fe1bae9e5d28d94a26377917 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 394 7.9E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03485 8e087056fe1bae9e5d28d94a26377917 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 413 7.9E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03485 8e087056fe1bae9e5d28d94a26377917 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 7.9E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03485 8e087056fe1bae9e5d28d94a26377917 439 SMART SM00387 319 416 5.6E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_03485 8e087056fe1bae9e5d28d94a26377917 439 PIRSF PIRSF037434 6 419 4.9E-63 T 12-10-2018 IPR017205 Signal transduction histidine kinase, ChrS TL08_03485 8e087056fe1bae9e5d28d94a26377917 439 Gene3D G3DSA:3.30.565.10 286 415 1.3E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_03485 8e087056fe1bae9e5d28d94a26377917 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 414 1.5E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_12075 b4b6ad89fe444ef3b5b7fb0f832f2784 161 Gene3D G3DSA:3.40.50.620 6 156 1.3E-30 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_12075 b4b6ad89fe444ef3b5b7fb0f832f2784 161 SUPERFAMILY SSF52402 11 150 2.6E-21 T 12-10-2018 TL08_12075 b4b6ad89fe444ef3b5b7fb0f832f2784 161 PRINTS PR01438 Universal stress protein signature 8 26 2.6E-8 T 12-10-2018 IPR006015 Universal stress protein A TL08_12075 b4b6ad89fe444ef3b5b7fb0f832f2784 161 PRINTS PR01438 Universal stress protein signature 125 147 2.6E-8 T 12-10-2018 IPR006015 Universal stress protein A TL08_12075 b4b6ad89fe444ef3b5b7fb0f832f2784 161 Pfam PF00582 Universal stress protein family 11 147 9.0E-18 T 12-10-2018 IPR006016 UspA TL08_05265 9ff4387e3e265ba039f59ffd5d4d8367 462 Pfam PF01595 Domain of unknown function DUF21 14 206 4.6E-34 T 12-10-2018 IPR002550 CNNM, transmembrane domain TL08_05265 9ff4387e3e265ba039f59ffd5d4d8367 462 SUPERFAMILY SSF54631 211 347 1.46E-24 T 12-10-2018 TL08_05265 9ff4387e3e265ba039f59ffd5d4d8367 462 Pfam PF00571 CBS domain 285 338 0.0019 T 12-10-2018 IPR000644 CBS domain TL08_05265 9ff4387e3e265ba039f59ffd5d4d8367 462 Pfam PF00571 CBS domain 228 276 6.0E-6 T 12-10-2018 IPR000644 CBS domain TL08_05265 9ff4387e3e265ba039f59ffd5d4d8367 462 Gene3D G3DSA:3.30.465.10 352 447 2.5E-17 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TL08_05265 9ff4387e3e265ba039f59ffd5d4d8367 462 Gene3D G3DSA:3.10.580.10 206 351 5.1E-35 T 12-10-2018 TL08_05265 9ff4387e3e265ba039f59ffd5d4d8367 462 SMART SM01091 354 448 2.4E-11 T 12-10-2018 IPR005170 Transporter-associated domain TL08_05265 9ff4387e3e265ba039f59ffd5d4d8367 462 Pfam PF03471 Transporter associated domain 357 447 1.7E-13 T 12-10-2018 IPR005170 Transporter-associated domain TL08_05265 9ff4387e3e265ba039f59ffd5d4d8367 462 SUPERFAMILY SSF56176 352 451 2.02E-14 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_03405 4064fc3f25d65dbad700a06d52b540b4 135 Gene3D G3DSA:3.10.180.10 2 135 4.2E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03405 4064fc3f25d65dbad700a06d52b540b4 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 131 1.9E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_03405 4064fc3f25d65dbad700a06d52b540b4 135 SUPERFAMILY SSF54593 3 133 7.52E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_14515 7bc51e0f76e9484d3ef7466bc99a2be9 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 127 4.6E-23 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_14515 7bc51e0f76e9484d3ef7466bc99a2be9 368 SUPERFAMILY SSF50129 5 195 3.04E-57 T 12-10-2018 IPR011032 GroES-like superfamily TL08_14515 7bc51e0f76e9484d3ef7466bc99a2be9 368 Gene3D G3DSA:3.90.180.10 9 362 2.0E-123 T 12-10-2018 TL08_14515 7bc51e0f76e9484d3ef7466bc99a2be9 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_14515 7bc51e0f76e9484d3ef7466bc99a2be9 368 SUPERFAMILY SSF51735 160 334 2.56E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14515 7bc51e0f76e9484d3ef7466bc99a2be9 368 Gene3D G3DSA:3.40.50.720 176 311 2.0E-123 T 12-10-2018 TL08_14515 7bc51e0f76e9484d3ef7466bc99a2be9 368 Pfam PF00107 Zinc-binding dehydrogenase 199 313 9.3E-19 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_14515 7bc51e0f76e9484d3ef7466bc99a2be9 368 SMART SM00829 15 365 6.8E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 Gene3D G3DSA:3.40.1190.10 131 351 3.6E-65 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 SUPERFAMILY SSF53244 353 497 2.29E-44 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 SUPERFAMILY SSF51984 39 129 3.01E-23 T 12-10-2018 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 Pfam PF02875 Mur ligase family, glutamate ligase domain 354 439 2.3E-24 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 Gene3D G3DSA:3.40.50.720 39 130 2.8E-29 T 12-10-2018 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 SUPERFAMILY SSF53623 128 352 1.24E-52 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 41 495 1.5E-142 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 Pfam PF01225 Mur ligase family, catalytic domain 41 140 2.3E-24 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 Pfam PF08245 Mur ligase middle domain 147 333 3.8E-26 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 Gene3D G3DSA:3.90.190.20 352 505 9.0E-53 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_09490 9c9ed2e616449c02e35d06d2353f3d8c 505 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 38 501 38.054 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_21115 c1ce45695a165d1a6416d4c94921824d 217 SUPERFAMILY SSF54909 120 191 3.1E-11 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_21115 c1ce45695a165d1a6416d4c94921824d 217 Pfam PF03992 Antibiotic biosynthesis monooxygenase 12 85 3.6E-8 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TL08_21115 c1ce45695a165d1a6416d4c94921824d 217 Pfam PF03992 Antibiotic biosynthesis monooxygenase 122 186 3.3E-6 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TL08_21115 c1ce45695a165d1a6416d4c94921824d 217 Gene3D G3DSA:3.30.70.100 117 215 6.8E-20 T 12-10-2018 TL08_21115 c1ce45695a165d1a6416d4c94921824d 217 Gene3D G3DSA:3.30.70.100 8 105 4.6E-20 T 12-10-2018 TL08_21115 c1ce45695a165d1a6416d4c94921824d 217 SUPERFAMILY SSF54909 8 104 8.72E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM01294 2010 2077 1.0E-5 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF47336 2004 2121 5.63E-23 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.40.366.10 2617 2914 3.3E-155 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.40.366.10 568 869 6.0E-148 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 409 2.7E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2355 2470 1.3E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.10.129.110 920 1209 3.4E-104 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.10.129.110 2964 3237 7.9E-85 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF51735 1721 1965 1.76E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF00550 Phosphopantetheine attachment site 3676 3741 1.1E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF00550 Phosphopantetheine attachment site 2012 2077 4.1E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00826 2974 3128 3.9E-56 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00826 931 1095 2.6E-70 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2106 2347 1.8E-78 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.5E-87 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2260 2276 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF50129 1407 1545 1.48E-23 T 12-10-2018 IPR011032 GroES-like superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:1.10.1200.10 3654 3747 1.7E-27 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:1.10.1200.10 1989 2081 3.4E-34 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3393 3573 1.1E-57 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1724 1904 2.4E-58 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.40.50.720 3238 3648 1.8E-110 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF52151 2616 2899 5.75E-69 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF08659 KR domain 1724 1902 1.2E-56 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF08659 KR domain 3393 3572 4.8E-59 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.30.70.3290 481 911 6.0E-148 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.40.50.720 1718 1970 3.4E-68 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1429 1485 4.5E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2473 2584 1.6E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 528 5.4E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF00698 Acyl transferase domain 2619 2927 5.2E-53 T 12-10-2018 IPR014043 Acyl transferase TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF00698 Acyl transferase domain 568 883 3.9E-72 T 12-10-2018 IPR014043 Acyl transferase TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00823 Phosphopantetheine attachment site 3674 3746 7.9E-25 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00823 Phosphopantetheine attachment site 2009 2081 1.4E-31 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF55048 2740 2801 8.89E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2619 2911 1.5E-114 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 570 866 2.4E-101 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3701 3716 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.30.70.3290 2536 2958 3.3E-155 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.40.47.10 2092 2524 7.4E-174 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.90.180.10 1391 1717 1.1E-117 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF53901 30 401 1.73E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF53901 2104 2467 1.33E-93 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.40.50.11460 1211 1386 5.0E-42 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF51735 1508 1685 6.84E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF51735 3238 3381 9.45E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00829 1409 1714 5.9E-165 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF08990 Erythronolide synthase docking 2 27 3.3E-5 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF51735 3392 3619 1.25E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF51735 1210 1387 2.49E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF52151 567 857 6.8E-63 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1536 1557 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF55048 692 753 3.92E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF13602 Zinc-binding dehydrogenase 1583 1714 7.9E-18 T 12-10-2018 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00825 Beta-ketoacyl synthase 2108 2523 9.1E-192 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SMART SM00825 Beta-ketoacyl synthase 36 462 9.0E-214 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 SUPERFAMILY SSF47336 3668 3747 3.53E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF14765 Polyketide synthase dehydratase 931 1203 1.7E-59 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Pfam PF14765 Polyketide synthase dehydratase 2974 3234 2.9E-49 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14590 3488d2f51d7fe6ea929a89d2fd0ebc95 3827 Gene3D G3DSA:3.40.47.10 25 480 1.3E-186 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05430 192ebda37677d5974fd864d9a14c267a 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 143 3.5E-29 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_05430 192ebda37677d5974fd864d9a14c267a 349 SUPERFAMILY SSF51735 148 311 4.03E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05430 192ebda37677d5974fd864d9a14c267a 349 SMART SM00829 8 341 1.5E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_05430 192ebda37677d5974fd864d9a14c267a 349 Gene3D G3DSA:3.90.180.10 13 341 6.4E-137 T 12-10-2018 TL08_05430 192ebda37677d5974fd864d9a14c267a 349 SUPERFAMILY SSF50129 6 172 4.11E-54 T 12-10-2018 IPR011032 GroES-like superfamily TL08_05430 192ebda37677d5974fd864d9a14c267a 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_05430 192ebda37677d5974fd864d9a14c267a 349 Gene3D G3DSA:3.40.50.720 159 313 6.4E-137 T 12-10-2018 TL08_05430 192ebda37677d5974fd864d9a14c267a 349 Pfam PF00107 Zinc-binding dehydrogenase 185 307 3.0E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_16555 7bf3d1655a1fa4566f43d7987c9132c8 342 Pfam PF00248 Aldo/keto reductase family 18 307 3.8E-72 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_16555 7bf3d1655a1fa4566f43d7987c9132c8 342 Gene3D G3DSA:3.20.20.100 1 314 7.2E-117 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_16555 7bf3d1655a1fa4566f43d7987c9132c8 342 SUPERFAMILY SSF51430 1 308 6.29E-101 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_16555 7bf3d1655a1fa4566f43d7987c9132c8 342 PRINTS PR00069 Aldo-keto reductase signature 105 123 9.4E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_16555 7bf3d1655a1fa4566f43d7987c9132c8 342 PRINTS PR00069 Aldo-keto reductase signature 41 65 9.4E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_16555 7bf3d1655a1fa4566f43d7987c9132c8 342 PRINTS PR00069 Aldo-keto reductase signature 136 153 9.4E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_01275 608c616cd0ac27c3b5048532da43130b 376 SUPERFAMILY SSF55979 4 118 1.92E-14 T 12-10-2018 TL08_01275 608c616cd0ac27c3b5048532da43130b 376 Gene3D G3DSA:3.10.150.10 126 245 7.6E-23 T 12-10-2018 TL08_01275 608c616cd0ac27c3b5048532da43130b 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 7 117 1.1E-17 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TL08_01275 608c616cd0ac27c3b5048532da43130b 376 Gene3D G3DSA:3.10.150.10 1 123 7.6E-20 T 12-10-2018 TL08_01275 608c616cd0ac27c3b5048532da43130b 376 SUPERFAMILY SSF55979 133 245 1.06E-17 T 12-10-2018 TL08_01275 608c616cd0ac27c3b5048532da43130b 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 133 242 3.3E-16 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 TL08_01275 608c616cd0ac27c3b5048532da43130b 376 SMART SM00480 19 364 1.9E-16 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TL08_01275 608c616cd0ac27c3b5048532da43130b 376 Gene3D G3DSA:3.10.150.10 251 368 1.3E-9 T 12-10-2018 TL08_01275 608c616cd0ac27c3b5048532da43130b 376 SUPERFAMILY SSF55979 249 367 2.51E-8 T 12-10-2018 TL08_08295 526ae21e5d043a21e50abfdca39cc34c 127 Gene3D G3DSA:3.10.180.10 8 115 4.1E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_08295 526ae21e5d043a21e50abfdca39cc34c 127 SUPERFAMILY SSF54593 12 116 1.28E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_08295 526ae21e5d043a21e50abfdca39cc34c 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 108 8.1E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_09285 91cc3812c389183a29cc91e580b034a6 89 SMART SM01387 8 88 1.0E-50 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_09285 91cc3812c389183a29cc91e580b034a6 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 6.3E-39 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_09285 91cc3812c389183a29cc91e580b034a6 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-20 T 12-10-2018 TL08_09285 91cc3812c389183a29cc91e580b034a6 89 Pfam PF00312 Ribosomal protein S15 8 88 4.5E-37 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_09285 91cc3812c389183a29cc91e580b034a6 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_09285 91cc3812c389183a29cc91e580b034a6 89 Gene3D G3DSA:1.10.287.10 2 89 5.3E-34 T 12-10-2018 TL08_09285 91cc3812c389183a29cc91e580b034a6 89 SUPERFAMILY SSF47060 3 89 5.59E-35 T 12-10-2018 IPR009068 S15/NS1, RNA-binding TL08_09285 91cc3812c389183a29cc91e580b034a6 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.368 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18670 5af37878bd750eaa26ee8a705b06f857 322 Pfam PF10099 Anti-sigma-K factor rskA 65 318 2.4E-12 T 12-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 TL08_18670 5af37878bd750eaa26ee8a705b06f857 322 Gene3D G3DSA:1.10.10.1320 13 78 8.5E-12 T 12-10-2018 TL08_00215 34ddc4da7302a280b4b4dec83b89ee94 460 Pfam PF01381 Helix-turn-helix 35 83 4.6E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_00215 34ddc4da7302a280b4b4dec83b89ee94 460 SUPERFAMILY SSF47413 30 78 1.3E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_00215 34ddc4da7302a280b4b4dec83b89ee94 460 SMART SM00530 32 87 4.0E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_00215 34ddc4da7302a280b4b4dec83b89ee94 460 Gene3D G3DSA:1.10.260.40 16 83 1.2E-7 T 12-10-2018 TL08_00215 34ddc4da7302a280b4b4dec83b89ee94 460 SUPERFAMILY SSF48452 211 349 5.06E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_00215 34ddc4da7302a280b4b4dec83b89ee94 460 Gene3D G3DSA:1.25.40.10 184 450 9.2E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15490 71a7ad3769952231c7b1ee15a643c0d8 298 SUPERFAMILY SSF161098 54 280 4.71E-54 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15490 71a7ad3769952231c7b1ee15a643c0d8 298 Gene3D G3DSA:1.10.3720.10 52 289 5.0E-61 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15490 71a7ad3769952231c7b1ee15a643c0d8 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 283 1.1E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_14770 d31b0886f374622bc67f968f2ceea0a1 396 Gene3D G3DSA:3.50.50.60 4 363 1.6E-86 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14770 d31b0886f374622bc67f968f2ceea0a1 396 SUPERFAMILY SSF54373 223 323 3.27E-11 T 12-10-2018 TL08_14770 d31b0886f374622bc67f968f2ceea0a1 396 Gene3D G3DSA:3.30.9.10 90 324 1.6E-86 T 12-10-2018 TL08_14770 d31b0886f374622bc67f968f2ceea0a1 396 Pfam PF01266 FAD dependent oxidoreductase 4 362 1.2E-59 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_14770 d31b0886f374622bc67f968f2ceea0a1 396 SUPERFAMILY SSF51905 2 381 4.6E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_16665 e472327c9047bc15e7524ce543f079e8 329 Gene3D G3DSA:3.90.180.10 12 325 2.1E-105 T 12-10-2018 TL08_16665 e472327c9047bc15e7524ce543f079e8 329 Pfam PF00107 Zinc-binding dehydrogenase 150 275 2.4E-19 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_16665 e472327c9047bc15e7524ce543f079e8 329 SMART SM00829 12 325 1.3E-5 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_16665 e472327c9047bc15e7524ce543f079e8 329 SUPERFAMILY SSF51735 115 292 8.16E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16665 e472327c9047bc15e7524ce543f079e8 329 SUPERFAMILY SSF50129 6 133 3.06E-26 T 12-10-2018 IPR011032 GroES-like superfamily TL08_16665 e472327c9047bc15e7524ce543f079e8 329 Pfam PF16884 N-terminal domain of oxidoreductase 7 102 9.8E-22 T 12-10-2018 TL08_16665 e472327c9047bc15e7524ce543f079e8 329 Gene3D G3DSA:3.40.50.720 118 296 2.1E-105 T 12-10-2018 TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 1 430 1.6E-143 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 Pfam PF04055 Radical SAM superfamily 137 308 4.7E-31 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 Pfam PF00919 Uncharacterized protein family UPF0004 1 90 1.4E-21 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 1 402 5.9E-137 T 12-10-2018 TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 SUPERFAMILY SSF102114 119 359 7.98E-61 T 12-10-2018 TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 Gene3D G3DSA:3.40.50.12160 1 120 3.7E-27 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 434 64.738 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 SMART SM00729 133 352 7.2E-58 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 Gene3D G3DSA:3.80.30.20 131 365 9.3E-91 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TL08_08535 59f6e6092f0fe5cb986108d0070efad6 480 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 137 157 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TL08_06895 4e6839a4bebd7fb5d8c0bce13bfe7a87 351 Gene3D G3DSA:2.60.40.3780 2 91 4.0E-29 T 12-10-2018 TL08_06895 4e6839a4bebd7fb5d8c0bce13bfe7a87 351 Gene3D G3DSA:2.40.440.10 194 336 3.4E-92 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TL08_06895 4e6839a4bebd7fb5d8c0bce13bfe7a87 351 Gene3D G3DSA:2.60.40.3710 102 348 3.4E-92 T 12-10-2018 TL08_06895 4e6839a4bebd7fb5d8c0bce13bfe7a87 351 SUPERFAMILY SSF141523 194 318 4.71E-27 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TL08_06895 4e6839a4bebd7fb5d8c0bce13bfe7a87 351 Pfam PF03734 L,D-transpeptidase catalytic domain 208 318 4.5E-15 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 Gene3D G3DSA:3.40.190.10 75 357 7.8E-108 T 12-10-2018 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 PIRSF PIRSF019574 29 390 1.1E-101 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 SUPERFAMILY SSF53850 71 390 2.03E-85 T 12-10-2018 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 Gene3D G3DSA:3.40.190.10 176 386 7.8E-108 T 12-10-2018 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 93 2.9E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 93 114 2.9E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 183 2.9E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 136 149 2.9E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 335 361 2.9E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 210 229 2.9E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 290 309 2.9E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 120 134 2.9E-48 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TL08_08920 c1ec407658a51ac4fe023f3976d01a59 390 Pfam PF13416 Bacterial extracellular solute-binding protein 91 356 2.4E-33 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 Gene3D G3DSA:3.30.565.10 267 411 2.4E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 SMART SM00387 308 409 4.9E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 Pfam PF00672 HAMP domain 149 197 6.3E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 SMART SM00388 202 266 0.002 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 SUPERFAMILY SSF55874 268 411 1.57E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 SUPERFAMILY SSF47384 186 261 2.94E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 357 3.4E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 389 3.4E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 Gene3D G3DSA:1.10.287.130 153 266 2.7E-15 T 12-10-2018 TL08_23555 cc8e70ed6bad8bd340b9f818eb6b2ed6 425 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 402 8.6E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_18325 c718fb8e81f7fe340432c182e431ffc5 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 218 1.1E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_18325 c718fb8e81f7fe340432c182e431ffc5 219 SUPERFAMILY SSF52172 1 177 8.46E-37 T 12-10-2018 IPR011006 CheY-like superfamily TL08_18325 c718fb8e81f7fe340432c182e431ffc5 219 Gene3D G3DSA:3.40.50.2300 1 121 2.3E-36 T 12-10-2018 TL08_18325 c718fb8e81f7fe340432c182e431ffc5 219 SMART SM00862 147 218 6.3E-31 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_18325 c718fb8e81f7fe340432c182e431ffc5 219 Pfam PF00072 Response regulator receiver domain 4 114 5.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_18325 c718fb8e81f7fe340432c182e431ffc5 219 SMART SM00448 2 113 2.0E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_18325 c718fb8e81f7fe340432c182e431ffc5 219 Gene3D G3DSA:1.10.10.10 126 219 2.3E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Gene3D G3DSA:3.30.470.20 120 402 2.6E-118 T 12-10-2018 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 SUPERFAMILY SSF56059 680 955 8.84E-94 T 12-10-2018 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 5.0E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 5.0E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 5.0E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 5.0E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 5.0E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 5.0E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 5.0E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Gene3D G3DSA:1.10.1030.10 407 551 1.0E-35 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 SUPERFAMILY SSF52440 559 681 8.49E-45 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 SUPERFAMILY SSF48108 396 548 5.23E-40 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 SUPERFAMILY SSF52440 1 127 4.6E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 SMART SM01096 422 545 6.5E-56 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1085 12.985 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 845 852 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Gene3D G3DSA:3.40.50.20 1 116 7.4E-48 T 12-10-2018 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 SUPERFAMILY SSF52335 964 1093 2.09E-35 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Pfam PF02142 MGS-like domain 978 1064 2.9E-19 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Gene3D G3DSA:3.40.50.1380 958 1097 9.5E-40 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 545 5.6E-35 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 SMART SM00851 977 1064 4.7E-30 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Gene3D G3DSA:3.40.50.20 557 669 1.1E-46 T 12-10-2018 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 SUPERFAMILY SSF56059 128 400 5.83E-102 T 12-10-2018 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 716 730 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.4E-66 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 881 6.7E-35 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_11500 e7b85af072326c8017c4d1bacf790478 1101 Gene3D G3DSA:3.30.470.20 672 957 1.0E-105 T 12-10-2018 TL08_00720 ed27adda49a4d95fdcb7c902a95d14d1 311 Pfam PF01061 ABC-2 type transporter 63 272 4.0E-25 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 Gene3D G3DSA:1.10.3060.10 615 831 2.6E-71 T 12-10-2018 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 Gene3D G3DSA:3.40.50.300 21 394 3.6E-178 T 12-10-2018 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 Pfam PF07516 SecA Wing and Scaffold domain 611 828 2.8E-65 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 Hamap MF_01382 Protein translocase subunit SecA [secA]. 2 831 19.77 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 SUPERFAMILY SSF81886 614 832 1.14E-68 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 SUPERFAMILY SSF52540 9 394 9.55E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 Gene3D G3DSA:3.40.50.300 397 613 5.5E-90 T 12-10-2018 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 SUPERFAMILY SSF81767 224 347 9.42E-44 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 ProSitePatterns PS01312 SecA family signature. 479 494 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 PRINTS PR00906 SecA protein signature 355 372 6.4E-69 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 PRINTS PR00906 SecA protein signature 60 84 6.4E-69 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 PRINTS PR00906 SecA protein signature 167 187 6.4E-69 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 PRINTS PR00906 SecA protein signature 392 405 6.4E-69 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 PRINTS PR00906 SecA protein signature 114 124 6.4E-69 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 PRINTS PR00906 SecA protein signature 98 112 6.4E-69 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 PRINTS PR00906 SecA protein signature 318 340 6.4E-69 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 25 816 0.0 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 Pfam PF07517 SecA DEAD-like domain 6 381 3.4E-126 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 SUPERFAMILY SSF52540 397 612 5.21E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 Pfam PF01043 SecA preprotein cross-linking domain 229 337 3.2E-36 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 SMART SM00958 225 337 4.8E-65 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 SMART SM00957 3 381 1.2E-272 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TL08_23260 0c15bc0625d9352cc1e94b06d0269b7b 975 Gene3D G3DSA:3.90.1440.10 226 347 3.6E-178 T 12-10-2018 TL08_16105 1c3b96da181ecf7d54d07d276cb08ac8 153 ProSitePatterns PS00552 MerR-type HTH domain signature. 12 34 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_16105 1c3b96da181ecf7d54d07d276cb08ac8 153 Pfam PF13411 MerR HTH family regulatory protein 10 76 3.7E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_16105 1c3b96da181ecf7d54d07d276cb08ac8 153 Gene3D G3DSA:1.10.1660.10 8 132 5.7E-31 T 12-10-2018 TL08_16105 1c3b96da181ecf7d54d07d276cb08ac8 153 SMART SM00422 9 79 3.9E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_16105 1c3b96da181ecf7d54d07d276cb08ac8 153 SUPERFAMILY SSF46955 9 125 5.86E-27 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_19055 998a21db222e60a050dc4645e8c4ca07 285 Gene3D G3DSA:3.20.20.30 1 280 6.5E-53 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_19055 998a21db222e60a050dc4645e8c4ca07 285 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 10 233 8.5E-87 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c TL08_19055 998a21db222e60a050dc4645e8c4ca07 285 SUPERFAMILY SSF51679 5 258 5.5E-52 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_19055 998a21db222e60a050dc4645e8c4ca07 285 Pfam PF00296 Luciferase-like monooxygenase 20 233 7.9E-39 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_14520 fc2549c388d93318d1797bbe9b657c6f 360 Gene3D G3DSA:3.60.15.10 55 264 1.1E-35 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_14520 fc2549c388d93318d1797bbe9b657c6f 360 SUPERFAMILY SSF56281 35 274 2.03E-38 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_14520 fc2549c388d93318d1797bbe9b657c6f 360 SMART SM00849 70 238 3.3E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_14520 fc2549c388d93318d1797bbe9b657c6f 360 Pfam PF00753 Metallo-beta-lactamase superfamily 74 210 3.8E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 3.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 Gene3D G3DSA:3.40.50.720 4 252 6.5E-81 T 12-10-2018 TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 SUPERFAMILY SSF51735 10 248 1.54E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 189 2.6E-5 T 12-10-2018 TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 247 5.2E-66 T 12-10-2018 TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12455 aaff5c6720b7bf7ff66ae739d509658c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05035 1877b0382dcc59b288907f533080ed56 150 SUPERFAMILY SSF54637 16 143 1.7E-26 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_05035 1877b0382dcc59b288907f533080ed56 150 Gene3D G3DSA:3.10.129.10 9 147 3.8E-26 T 12-10-2018 TL08_05035 1877b0382dcc59b288907f533080ed56 150 Pfam PF03061 Thioesterase superfamily 29 110 4.7E-10 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TL08_11750 633de86ae0dae061b28c3b8084e7bc83 237 Gene3D G3DSA:3.40.50.300 1 229 1.1E-56 T 12-10-2018 TL08_11750 633de86ae0dae061b28c3b8084e7bc83 237 Pfam PF00005 ABC transporter 18 156 8.4E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_11750 633de86ae0dae061b28c3b8084e7bc83 237 SUPERFAMILY SSF52540 2 220 1.71E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11750 633de86ae0dae061b28c3b8084e7bc83 237 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_11750 633de86ae0dae061b28c3b8084e7bc83 237 SMART SM00382 26 204 4.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 SUPERFAMILY SSF50621 244 376 6.02E-48 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 40 50 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 PRINTS PR00992 Alanine racemase signature 304 321 4.1E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 PRINTS PR00992 Alanine racemase signature 211 238 4.1E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 PRINTS PR00992 Alanine racemase signature 132 144 4.1E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 PRINTS PR00992 Alanine racemase signature 266 281 4.1E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 PRINTS PR00992 Alanine racemase signature 359 372 4.1E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 PRINTS PR00992 Alanine racemase signature 35 51 4.1E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 PRINTS PR00992 Alanine racemase signature 71 89 4.1E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 PRINTS PR00992 Alanine racemase signature 283 298 4.1E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 PRINTS PR00992 Alanine racemase signature 169 180 4.1E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 Gene3D G3DSA:3.20.20.10 17 233 3.2E-124 T 12-10-2018 IPR029066 PLP-binding barrel TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 TIGRFAM TIGR00492 alr: alanine racemase 12 374 8.0E-86 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 Hamap MF_01201 Alanine racemase. 8 378 31.437 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 SMART SM01005 250 378 5.7E-63 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 Gene3D G3DSA:2.40.37.10 15 375 3.2E-124 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 Pfam PF00842 Alanine racemase, C-terminal domain 250 375 3.1E-43 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 SUPERFAMILY SSF51419 15 251 2.13E-56 T 12-10-2018 IPR029066 PLP-binding barrel TL08_24865 8de88b4bfe92e4e6e08f2a9e0f27e197 397 Pfam PF01168 Alanine racemase, N-terminal domain 15 238 1.8E-59 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_15270 c83e926068e70170acaaabf2e3fabe52 322 SUPERFAMILY SSF103481 53 149 3.92E-14 T 12-10-2018 TL08_15270 c83e926068e70170acaaabf2e3fabe52 322 SUPERFAMILY SSF103481 196 294 5.1E-12 T 12-10-2018 TL08_15270 c83e926068e70170acaaabf2e3fabe52 322 Pfam PF00892 EamA-like transporter family 18 146 5.4E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_15270 c83e926068e70170acaaabf2e3fabe52 322 Pfam PF00892 EamA-like transporter family 164 293 1.9E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_12330 dcbfcef3f87af934288fb4da40c9d475 330 Pfam PF01758 Sodium Bile acid symporter family 45 222 6.0E-41 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TL08_12330 dcbfcef3f87af934288fb4da40c9d475 330 Gene3D G3DSA:1.20.1530.20 4 310 6.2E-105 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 SMART SM00382 360 527 1.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 SMART SM00382 26 242 7.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 Pfam PF00005 ABC transporter 18 197 3.2E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 Gene3D G3DSA:3.40.50.300 1 297 9.2E-48 T 12-10-2018 TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 SUPERFAMILY SSF52540 317 527 1.4E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 Pfam PF00005 ABC transporter 353 481 1.0E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 Pfam PF12848 ABC transporter 239 309 1.7E-9 T 12-10-2018 IPR032781 ABC-transporter extension domain TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 Gene3D G3DSA:3.40.50.300 301 540 1.8E-54 T 12-10-2018 TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 SUPERFAMILY SSF52540 3 239 1.13E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11890 1ec6f21e04863c1ce8f74861a14d4f5a 542 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_20280 18309b779dbddb7026c174e0f9a3d2d8 758 Pfam PF13245 AAA domain 172 548 1.9E-11 T 12-10-2018 TL08_20280 18309b779dbddb7026c174e0f9a3d2d8 758 Pfam PF13538 UvrD-like helicase C-terminal domain 686 734 2.2E-8 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain TL08_20280 18309b779dbddb7026c174e0f9a3d2d8 758 SUPERFAMILY SSF52540 160 737 3.26E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20280 18309b779dbddb7026c174e0f9a3d2d8 758 Gene3D G3DSA:3.40.50.300 576 750 2.6E-14 T 12-10-2018 TL08_20280 18309b779dbddb7026c174e0f9a3d2d8 758 Gene3D G3DSA:3.40.50.300 428 575 5.3E-8 T 12-10-2018 TL08_20280 18309b779dbddb7026c174e0f9a3d2d8 758 Gene3D G3DSA:3.40.50.300 157 309 9.0E-10 T 12-10-2018 TL08_24720 6c3e1ab79b34dd41b0125b13b0d5c373 447 Pfam PF04024 PspC domain 31 84 4.5E-13 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal TL08_24720 6c3e1ab79b34dd41b0125b13b0d5c373 447 Pfam PF13581 Histidine kinase-like ATPase domain 349 408 1.1E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_24720 6c3e1ab79b34dd41b0125b13b0d5c373 447 Gene3D G3DSA:3.30.565.10 314 445 4.1E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_24720 6c3e1ab79b34dd41b0125b13b0d5c373 447 SUPERFAMILY SSF55874 321 442 2.05E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_24030 f37bd5a139ae239c03c8268ac8109ae2 293 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 54 290 6.9E-98 T 12-10-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 TL08_24030 f37bd5a139ae239c03c8268ac8109ae2 293 SUPERFAMILY SSF53167 38 290 2.5E-78 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TL08_24030 f37bd5a139ae239c03c8268ac8109ae2 293 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 108 149 - T 12-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 TL08_24030 f37bd5a139ae239c03c8268ac8109ae2 293 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 54 290 5.8E-78 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TL08_24030 f37bd5a139ae239c03c8268ac8109ae2 293 Pfam PF01048 Phosphorylase superfamily 54 290 4.2E-40 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TL08_24030 f37bd5a139ae239c03c8268ac8109ae2 293 PIRSF PIRSF000477 27 293 1.1E-91 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TL08_24030 f37bd5a139ae239c03c8268ac8109ae2 293 Gene3D G3DSA:3.40.50.1580 28 292 4.2E-89 T 12-10-2018 TL08_08885 ccebd05c0a4829b6661e9239df1c02f5 187 Hamap MF_00040 Ribosome-recycling factor [frr]. 5 187 26.37 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 TL08_08885 ccebd05c0a4829b6661e9239df1c02f5 187 Gene3D G3DSA:1.10.132.20 14 184 1.0E-63 T 12-10-2018 TL08_08885 ccebd05c0a4829b6661e9239df1c02f5 187 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 187 5.0E-63 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 TL08_08885 ccebd05c0a4829b6661e9239df1c02f5 187 Gene3D G3DSA:3.30.1360.40 33 107 1.0E-63 T 12-10-2018 TL08_08885 ccebd05c0a4829b6661e9239df1c02f5 187 Pfam PF01765 Ribosome recycling factor 23 185 6.2E-59 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 TL08_08885 ccebd05c0a4829b6661e9239df1c02f5 187 SUPERFAMILY SSF55194 5 186 1.2E-66 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 TL08_18560 1c867990d2e5160282ae1dda50ca8029 227 SUPERFAMILY SSF46689 16 94 2.57E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18560 1c867990d2e5160282ae1dda50ca8029 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 75 5.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18560 1c867990d2e5160282ae1dda50ca8029 227 Gene3D G3DSA:1.10.357.10 25 217 4.4E-28 T 12-10-2018 TL08_18430 eaa3535ecf879ad90a60c041538edaa8 336 Gene3D G3DSA:1.10.260.40 3 64 4.4E-20 T 12-10-2018 TL08_18430 eaa3535ecf879ad90a60c041538edaa8 336 Gene3D G3DSA:3.40.50.2300 164 291 3.7E-28 T 12-10-2018 TL08_18430 eaa3535ecf879ad90a60c041538edaa8 336 Gene3D G3DSA:3.40.50.2300 65 306 3.7E-28 T 12-10-2018 TL08_18430 eaa3535ecf879ad90a60c041538edaa8 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 58 2.3E-11 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_18430 eaa3535ecf879ad90a60c041538edaa8 336 SMART SM00354 9 81 1.5E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_18430 eaa3535ecf879ad90a60c041538edaa8 336 SUPERFAMILY SSF53822 70 333 7.07E-26 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_18430 eaa3535ecf879ad90a60c041538edaa8 336 SUPERFAMILY SSF47413 8 69 2.33E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_18430 eaa3535ecf879ad90a60c041538edaa8 336 Pfam PF13377 Periplasmic binding protein-like domain 172 331 2.9E-25 T 12-10-2018 TL08_17290 e279e4df375f9bfa84f8547c43e95cfa 335 PIRSF PIRSF006278 1 335 1.2E-116 T 12-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase TL08_17290 e279e4df375f9bfa84f8547c43e95cfa 335 Gene3D G3DSA:3.40.50.1100 16 331 7.8E-110 T 12-10-2018 TL08_17290 e279e4df375f9bfa84f8547c43e95cfa 335 SUPERFAMILY SSF53686 5 333 3.16E-94 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_17290 e279e4df375f9bfa84f8547c43e95cfa 335 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 334 5.8E-156 T 12-10-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 TL08_17290 e279e4df375f9bfa84f8547c43e95cfa 335 Gene3D G3DSA:3.40.50.1100 67 165 7.8E-110 T 12-10-2018 TL08_17290 e279e4df375f9bfa84f8547c43e95cfa 335 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 320 4.5E-43 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_00140 7fab0529ed7878c28ff4fd4485059094 498 Pfam PF13672 Protein phosphatase 2C 18 197 1.6E-11 T 12-10-2018 TL08_00140 7fab0529ed7878c28ff4fd4485059094 498 SMART SM00332 2 233 1.7E-24 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_00140 7fab0529ed7878c28ff4fd4485059094 498 Gene3D G3DSA:3.60.40.10 2 236 6.8E-65 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_00140 7fab0529ed7878c28ff4fd4485059094 498 SMART SM00331 11 235 2.5E-39 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_00140 7fab0529ed7878c28ff4fd4485059094 498 SUPERFAMILY SSF81606 4 234 1.96E-62 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_24555 25f750148c44287893ef53420d2648a3 602 SUPERFAMILY SSF56672 41 267 3.02E-35 T 12-10-2018 TL08_24555 25f750148c44287893ef53420d2648a3 602 Gene3D G3DSA:2.30.40.20 67 105 2.7E-15 T 12-10-2018 TL08_24555 25f750148c44287893ef53420d2648a3 602 Gene3D G3DSA:3.30.70.270 106 266 2.7E-15 T 12-10-2018 TL08_24555 25f750148c44287893ef53420d2648a3 602 Gene3D G3DSA:1.10.150.20 202 260 2.7E-15 T 12-10-2018 TL08_24555 25f750148c44287893ef53420d2648a3 602 Pfam PF00817 impB/mucB/samB family 55 181 9.7E-13 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TL08_10175 05603e351a2b7b1937f2595c9f445a6d 430 Pfam PF00589 Phage integrase family 237 398 2.4E-18 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_10175 05603e351a2b7b1937f2595c9f445a6d 430 SUPERFAMILY SSF56349 79 409 8.54E-55 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_10175 05603e351a2b7b1937f2595c9f445a6d 430 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 80 134 1.5E-6 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TL08_10175 05603e351a2b7b1937f2595c9f445a6d 430 Gene3D G3DSA:1.10.150.130 75 213 1.6E-21 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_10175 05603e351a2b7b1937f2595c9f445a6d 430 Gene3D G3DSA:1.10.443.10 218 414 4.8E-38 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 Gene3D G3DSA:1.10.260.40 1 58 6.4E-20 T 12-10-2018 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 SUPERFAMILY SSF53822 62 341 8.52E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.5E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 Gene3D G3DSA:3.40.50.2300 64 314 9.6E-69 T 12-10-2018 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.4E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.4E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 SUPERFAMILY SSF47413 3 60 2.69E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 SMART SM00354 2 72 3.8E-25 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 Gene3D G3DSA:3.40.50.2300 170 299 9.6E-69 T 12-10-2018 TL08_20415 a8c937e7e40416fd507a8fca7b1cc20b 354 Pfam PF13377 Periplasmic binding protein-like domain 178 338 7.3E-34 T 12-10-2018 TL08_00740 08e8130c58b3f17aaa3b8056187fb914 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 4.4E-8 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_00740 08e8130c58b3f17aaa3b8056187fb914 328 Gene3D G3DSA:3.40.50.720 120 262 1.4E-98 T 12-10-2018 TL08_00740 08e8130c58b3f17aaa3b8056187fb914 328 SUPERFAMILY SSF50129 1 138 1.83E-37 T 12-10-2018 IPR011032 GroES-like superfamily TL08_00740 08e8130c58b3f17aaa3b8056187fb914 328 Pfam PF00107 Zinc-binding dehydrogenase 151 263 4.5E-26 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_00740 08e8130c58b3f17aaa3b8056187fb914 328 SUPERFAMILY SSF51735 111 270 1.47E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_00740 08e8130c58b3f17aaa3b8056187fb914 328 SMART SM00829 10 326 3.1E-30 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_00740 08e8130c58b3f17aaa3b8056187fb914 328 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 327 3.8E-132 T 12-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 TL08_00740 08e8130c58b3f17aaa3b8056187fb914 328 Gene3D G3DSA:3.90.180.10 13 326 1.4E-98 T 12-10-2018 TL08_25395 d8bfbb04dc29772b767800169123b71c 200 SUPERFAMILY SSF88659 125 193 2.62E-7 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_25395 d8bfbb04dc29772b767800169123b71c 200 Pfam PF04542 Sigma-70 region 2 40 105 1.8E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_25395 d8bfbb04dc29772b767800169123b71c 200 SUPERFAMILY SSF88946 24 117 5.97E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_25395 d8bfbb04dc29772b767800169123b71c 200 Gene3D G3DSA:1.10.1740.10 19 106 3.7E-14 T 12-10-2018 TL08_25395 d8bfbb04dc29772b767800169123b71c 200 Gene3D G3DSA:1.10.10.10 116 195 5.7E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25395 d8bfbb04dc29772b767800169123b71c 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 192 2.1E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_20100 c07b42542c325043807d7efdb9354f46 195 Gene3D G3DSA:3.40.630.30 5 184 2.7E-17 T 12-10-2018 TL08_20100 c07b42542c325043807d7efdb9354f46 195 Pfam PF00583 Acetyltransferase (GNAT) family 84 168 4.3E-9 T 12-10-2018 IPR000182 GNAT domain TL08_20100 c07b42542c325043807d7efdb9354f46 195 SUPERFAMILY SSF55729 4 192 1.98E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_11665 4896dfc045043fc676e1422c28552cbf 145 SUPERFAMILY SSF54427 1 127 1.37E-31 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_11665 4896dfc045043fc676e1422c28552cbf 145 Pfam PF12680 SnoaL-like domain 10 115 3.8E-14 T 12-10-2018 IPR037401 SnoaL-like domain TL08_11665 4896dfc045043fc676e1422c28552cbf 145 Gene3D G3DSA:3.10.450.50 1 136 6.4E-37 T 12-10-2018 TL08_13820 2f08c4813331962c16bf03347ad4f9f5 228 SUPERFAMILY SSF46689 179 226 5.38E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_13820 2f08c4813331962c16bf03347ad4f9f5 228 SMART SM00342 141 225 1.3E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_13820 2f08c4813331962c16bf03347ad4f9f5 228 Gene3D G3DSA:1.10.10.60 130 228 3.6E-19 T 12-10-2018 TL08_13820 2f08c4813331962c16bf03347ad4f9f5 228 Pfam PF12833 Helix-turn-helix domain 149 227 3.5E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_07465 547407520e82397a11d7ef9a56bd5ca4 285 Pfam PF06267 Family of unknown function (DUF1028) 2 187 2.7E-48 T 12-10-2018 IPR010430 Protein of unknown function DUF1028 TL08_07465 547407520e82397a11d7ef9a56bd5ca4 285 SUPERFAMILY SSF56235 2 198 6.56E-46 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_07465 547407520e82397a11d7ef9a56bd5ca4 285 Gene3D G3DSA:3.60.20.10 1 206 7.2E-55 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_14700 fa8b645e94490b17da1f3965821d1e98 739 SUPERFAMILY SSF53067 30 518 9.29E-9 T 12-10-2018 TL08_14700 fa8b645e94490b17da1f3965821d1e98 739 Gene3D G3DSA:3.30.420.40 28 140 9.8E-6 T 12-10-2018 TL08_14700 fa8b645e94490b17da1f3965821d1e98 739 Pfam PF01968 Hydantoinase/oxoprolinase 217 524 1.8E-70 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TL08_14700 fa8b645e94490b17da1f3965821d1e98 739 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 30 196 1.1E-22 T 12-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 TL08_24170 e2f9dd5fe8269c04d5cacf3ee54d655d 377 Gene3D G3DSA:3.40.50.1820 91 376 1.8E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_24170 e2f9dd5fe8269c04d5cacf3ee54d655d 377 Pfam PF12146 Serine aminopeptidase, S33 128 357 9.0E-9 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 TL08_24170 e2f9dd5fe8269c04d5cacf3ee54d655d 377 SUPERFAMILY SSF53474 82 376 7.61E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15030 7b86fbd7a781d0f1007e824c5f64dc53 444 Gene3D G3DSA:3.40.190.10 65 363 9.6E-105 T 12-10-2018 TL08_15030 7b86fbd7a781d0f1007e824c5f64dc53 444 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 154 171 - T 12-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 TL08_15030 7b86fbd7a781d0f1007e824c5f64dc53 444 Pfam PF01547 Bacterial extracellular solute-binding protein 59 340 1.3E-29 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_15030 7b86fbd7a781d0f1007e824c5f64dc53 444 Gene3D G3DSA:3.40.190.10 158 412 9.6E-105 T 12-10-2018 TL08_15030 7b86fbd7a781d0f1007e824c5f64dc53 444 SUPERFAMILY SSF53850 50 429 1.88E-65 T 12-10-2018 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 SUPERFAMILY SSF50104 127 270 9.63E-55 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 3.3E-124 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 SUPERFAMILY SSF50249 3 126 1.3E-48 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 SMART SM01382 125 253 1.1E-86 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 PIRSF PIRSF002158 3 274 5.7E-93 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 5.6E-54 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 SMART SM01383 42 119 1.7E-40 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 Gene3D G3DSA:4.10.950.10 197 272 2.0E-29 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 Gene3D G3DSA:2.40.50.140 1 115 2.5E-46 T 12-10-2018 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 47.042 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 119 3.6E-32 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03000 b22aeef68a33ae345de3bde234c8c8ed 277 Gene3D G3DSA:2.30.30.30 119 196 7.5E-32 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 TL08_19470 9ea5c13cd6e2b67d8260001d3dfdb9c4 316 Gene3D G3DSA:1.10.3720.10 90 310 1.1E-21 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19470 9ea5c13cd6e2b67d8260001d3dfdb9c4 316 SUPERFAMILY SSF161098 89 296 2.75E-19 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19470 9ea5c13cd6e2b67d8260001d3dfdb9c4 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.9E-34 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 PRINTS PR00151 Porphobilinogen deaminase signature 226 243 8.3E-25 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 PRINTS PR00151 Porphobilinogen deaminase signature 71 90 8.3E-25 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 PRINTS PR00151 Porphobilinogen deaminase signature 119 136 8.3E-25 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 PRINTS PR00151 Porphobilinogen deaminase signature 138 155 8.3E-25 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 PIRSF PIRSF001438 1 310 4.8E-106 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 299 2.5E-90 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 223 299 1.0E-15 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 Gene3D G3DSA:3.40.190.10 5 210 3.0E-75 T 12-10-2018 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 206 1.6E-68 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 227 243 - T 12-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 301 34.099 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 Gene3D G3DSA:3.30.160.40 217 307 1.8E-16 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 SUPERFAMILY SSF53850 3 211 1.63E-66 T 12-10-2018 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 Gene3D G3DSA:3.40.190.10 95 194 3.0E-75 T 12-10-2018 TL08_02385 30df6d2f2aa9c6aa2c1477237d552085 311 SUPERFAMILY SSF54782 216 304 1.29E-14 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_19155 54cc2e29dce64b837fd99a36b3a7f7b5 238 Gene3D G3DSA:3.40.50.12740 19 225 2.7E-29 T 12-10-2018 TL08_19155 54cc2e29dce64b837fd99a36b3a7f7b5 238 SUPERFAMILY SSF52172 18 143 1.37E-5 T 12-10-2018 IPR011006 CheY-like superfamily TL08_19155 54cc2e29dce64b837fd99a36b3a7f7b5 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 219 1.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_19155 54cc2e29dce64b837fd99a36b3a7f7b5 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 1.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_19155 54cc2e29dce64b837fd99a36b3a7f7b5 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 1.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_19155 54cc2e29dce64b837fd99a36b3a7f7b5 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 1.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_19155 54cc2e29dce64b837fd99a36b3a7f7b5 238 SMART SM00421 162 219 1.1E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_19155 54cc2e29dce64b837fd99a36b3a7f7b5 238 SUPERFAMILY SSF46894 156 225 4.42E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_19155 54cc2e29dce64b837fd99a36b3a7f7b5 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02150 4c5a2c77425e2ed8b9e2bec386c920d4 347 Gene3D G3DSA:3.40.50.10490 6 188 2.1E-42 T 12-10-2018 TL08_02150 4c5a2c77425e2ed8b9e2bec386c920d4 347 Gene3D G3DSA:3.40.50.10490 195 346 1.0E-33 T 12-10-2018 TL08_02150 4c5a2c77425e2ed8b9e2bec386c920d4 347 Pfam PF01380 SIS domain 207 326 3.8E-11 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TL08_02150 4c5a2c77425e2ed8b9e2bec386c920d4 347 Pfam PF01380 SIS domain 46 167 1.0E-14 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TL08_02150 4c5a2c77425e2ed8b9e2bec386c920d4 347 SUPERFAMILY SSF53697 10 345 1.22E-64 T 12-10-2018 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 PRINTS PR00142 RecA protein signature 96 125 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 PRINTS PR00142 RecA protein signature 130 159 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 PRINTS PR00142 RecA protein signature 300 317 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 PRINTS PR00142 RecA protein signature 246 275 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 PRINTS PR00142 RecA protein signature 213 241 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 PRINTS PR00142 RecA protein signature 168 197 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 Gene3D G3DSA:3.40.50.300 29 270 3.7E-84 T 12-10-2018 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 SUPERFAMILY SSF54752 271 329 1.02E-20 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 7 327 3.0E-173 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 SMART SM00382 60 231 4.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 Gene3D G3DSA:3.30.250.10 271 349 3.5E-31 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 Pfam PF00154 recA bacterial DNA recombination protein 10 271 5.3E-143 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 SUPERFAMILY SSF52540 7 270 3.67E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 Hamap MF_00268 Protein RecA [recA]. 8 332 52.852 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TL08_08480 33f7f998b12bc1295a0676c4317aef7e 349 ProSitePatterns PS00321 recA signature. 216 224 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 TL08_14990 a16ba2c864c90327d86c575f989e1304 644 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 641 29.935 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 TL08_14990 a16ba2c864c90327d86c575f989e1304 644 SUPERFAMILY SSF110942 524 640 1.03E-30 T 12-10-2018 IPR037196 HSP90, C-terminal domain TL08_14990 a16ba2c864c90327d86c575f989e1304 644 SUPERFAMILY SSF55874 5 218 4.45E-58 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_14990 a16ba2c864c90327d86c575f989e1304 644 Gene3D G3DSA:3.30.230.80 242 409 2.6E-66 T 12-10-2018 TL08_14990 a16ba2c864c90327d86c575f989e1304 644 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 183 1.3E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_14990 a16ba2c864c90327d86c575f989e1304 644 Gene3D G3DSA:3.40.50.11260 410 497 6.6E-32 T 12-10-2018 TL08_14990 a16ba2c864c90327d86c575f989e1304 644 Gene3D G3DSA:3.30.565.10 1 230 1.2E-71 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_14990 a16ba2c864c90327d86c575f989e1304 644 SUPERFAMILY SSF54211 243 496 4.32E-96 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_14990 a16ba2c864c90327d86c575f989e1304 644 SMART SM00387 28 185 3.7E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_14990 a16ba2c864c90327d86c575f989e1304 644 PRINTS PR00775 90kDa heat shock protein signature 123 145 2.9E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TL08_14990 a16ba2c864c90327d86c575f989e1304 644 PRINTS PR00775 90kDa heat shock protein signature 27 49 2.9E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TL08_14990 a16ba2c864c90327d86c575f989e1304 644 PRINTS PR00775 90kDa heat shock protein signature 94 111 2.9E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TL08_14990 a16ba2c864c90327d86c575f989e1304 644 PRINTS PR00775 90kDa heat shock protein signature 196 214 2.9E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TL08_14990 a16ba2c864c90327d86c575f989e1304 644 PRINTS PR00775 90kDa heat shock protein signature 76 93 2.9E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TL08_14990 a16ba2c864c90327d86c575f989e1304 644 PRINTS PR00775 90kDa heat shock protein signature 173 190 2.9E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TL08_14990 a16ba2c864c90327d86c575f989e1304 644 PRINTS PR00775 90kDa heat shock protein signature 6 26 2.9E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal TL08_14990 a16ba2c864c90327d86c575f989e1304 644 PIRSF PIRSF002583 2 644 8.3E-215 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 TL08_14990 a16ba2c864c90327d86c575f989e1304 644 Gene3D G3DSA:1.20.120.790 502 640 2.6E-38 T 12-10-2018 IPR037196 HSP90, C-terminal domain TL08_14990 a16ba2c864c90327d86c575f989e1304 644 Pfam PF00183 Hsp90 protein 237 642 1.3E-130 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 TL08_14850 d78977439cd3a361c4b4f10dd0525a97 336 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 7 329 3.1E-129 T 12-10-2018 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB TL08_14850 d78977439cd3a361c4b4f10dd0525a97 336 PIRSF PIRSF001439 2 329 5.5E-79 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TL08_14850 d78977439cd3a361c4b4f10dd0525a97 336 Gene3D G3DSA:3.40.50.720 135 302 3.0E-90 T 12-10-2018 TL08_14850 d78977439cd3a361c4b4f10dd0525a97 336 SUPERFAMILY SSF51735 8 328 1.9E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14850 d78977439cd3a361c4b4f10dd0525a97 336 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 24 319 4.9E-32 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TL08_14850 d78977439cd3a361c4b4f10dd0525a97 336 Gene3D G3DSA:3.30.1780.10 16 321 3.0E-90 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 TL08_10765 7d627b0fba6b8214ea730d826904bf0f 970 Pfam PF02347 Glycine cleavage system P-protein 468 747 8.4E-13 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TL08_10765 7d627b0fba6b8214ea730d826904bf0f 970 Pfam PF02347 Glycine cleavage system P-protein 30 456 9.4E-171 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TL08_10765 7d627b0fba6b8214ea730d826904bf0f 970 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 31 962 0.0 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TL08_10765 7d627b0fba6b8214ea730d826904bf0f 970 SUPERFAMILY SSF53383 485 964 4.98E-99 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_10765 7d627b0fba6b8214ea730d826904bf0f 970 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 22 968 24.983 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TL08_10765 7d627b0fba6b8214ea730d826904bf0f 970 Gene3D G3DSA:3.90.1150.10 779 917 7.2E-37 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_10765 7d627b0fba6b8214ea730d826904bf0f 970 SUPERFAMILY SSF53383 31 456 1.1E-97 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_10765 7d627b0fba6b8214ea730d826904bf0f 970 Gene3D G3DSA:3.40.640.10 110 370 9.7E-102 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_10765 7d627b0fba6b8214ea730d826904bf0f 970 Gene3D G3DSA:3.40.640.10 537 758 5.4E-60 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_03615 8460089e828f427667dc1a3e2bdfd63e 310 SUPERFAMILY SSF54427 172 290 1.41E-12 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_03615 8460089e828f427667dc1a3e2bdfd63e 310 Gene3D G3DSA:1.10.1740.10 4 75 4.8E-10 T 12-10-2018 TL08_03615 8460089e828f427667dc1a3e2bdfd63e 310 Pfam PF08281 Sigma-70, region 4 109 159 2.1E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_03615 8460089e828f427667dc1a3e2bdfd63e 310 Pfam PF04542 Sigma-70 region 2 10 72 4.6E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_03615 8460089e828f427667dc1a3e2bdfd63e 310 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 160 1.0E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_03615 8460089e828f427667dc1a3e2bdfd63e 310 Gene3D G3DSA:3.10.450.50 167 299 3.3E-9 T 12-10-2018 TL08_03615 8460089e828f427667dc1a3e2bdfd63e 310 Gene3D G3DSA:1.10.10.10 94 164 8.7E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03615 8460089e828f427667dc1a3e2bdfd63e 310 SUPERFAMILY SSF88659 81 160 1.0E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_03615 8460089e828f427667dc1a3e2bdfd63e 310 SUPERFAMILY SSF88946 9 90 5.49E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_12660 3e17fdf840ce206c8c3234077cad8783 259 Gene3D G3DSA:3.40.50.300 4 249 1.5E-58 T 12-10-2018 TL08_12660 3e17fdf840ce206c8c3234077cad8783 259 Pfam PF00005 ABC transporter 26 172 5.7E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12660 3e17fdf840ce206c8c3234077cad8783 259 SMART SM00382 35 222 1.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12660 3e17fdf840ce206c8c3234077cad8783 259 SUPERFAMILY SSF52540 11 230 2.89E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12660 3e17fdf840ce206c8c3234077cad8783 259 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_08815 8eaed9cead7478bddf0f000bf098a264 314 SUPERFAMILY SSF161098 87 267 1.02E-22 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08815 8eaed9cead7478bddf0f000bf098a264 314 Gene3D G3DSA:1.10.3720.10 79 296 3.8E-19 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08815 8eaed9cead7478bddf0f000bf098a264 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 296 2.8E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_01650 15a1dce7a1daa9d9f2aafe2db13f8a00 358 Gene3D G3DSA:1.20.150.30 19 140 2.2E-21 T 12-10-2018 TL08_01650 15a1dce7a1daa9d9f2aafe2db13f8a00 358 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 19 357 1.0E-118 T 12-10-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated TL08_01650 15a1dce7a1daa9d9f2aafe2db13f8a00 358 Pfam PF10103 Zincin-like metallopeptidase 19 353 4.0E-105 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 TL08_01650 15a1dce7a1daa9d9f2aafe2db13f8a00 358 SUPERFAMILY SSF55486 18 356 2.34E-94 T 12-10-2018 TL08_01650 15a1dce7a1daa9d9f2aafe2db13f8a00 358 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 19 357 1.5E-100 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 SUPERFAMILY SSF81464 17 115 2.29E-21 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 Gene3D G3DSA:1.10.287.90 40 114 5.6E-15 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 182 235 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 Gene3D G3DSA:2.60.40.420 115 287 8.9E-37 T 12-10-2018 IPR008972 Cupredoxin TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 129 241 1.0E-13 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 43 251 8.1E-45 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 34 107 9.7E-5 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 224 241 6.7E-8 T 12-10-2018 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 206 223 6.7E-8 T 12-10-2018 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 88 100 6.7E-8 T 12-10-2018 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 123 142 6.7E-8 T 12-10-2018 TL08_21785 79243f635052f56e7a8ca4818124fa2c 305 SUPERFAMILY SSF49503 122 260 1.22E-33 T 12-10-2018 IPR008972 Cupredoxin TL08_07840 395d7ee9b696878ccb3b2b44b8af9611 1670 SUPERFAMILY SSF51735 1000 1271 5.84E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_07840 395d7ee9b696878ccb3b2b44b8af9611 1670 PIRSF PIRSF036761 10 1670 0.0 T 12-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 TL08_07840 395d7ee9b696878ccb3b2b44b8af9611 1670 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 85 1666 0.0 T 12-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 TL08_07840 395d7ee9b696878ccb3b2b44b8af9611 1670 SUPERFAMILY SSF53223 814 1011 1.63E-22 T 12-10-2018 TL08_06650 71e1bd1d56bde62a5cd00e0fc9079fd5 250 Gene3D G3DSA:3.40.50.150 21 201 1.8E-33 T 12-10-2018 TL08_06650 71e1bd1d56bde62a5cd00e0fc9079fd5 250 Pfam PF08241 Methyltransferase domain 48 138 4.0E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_06650 71e1bd1d56bde62a5cd00e0fc9079fd5 250 SUPERFAMILY SSF53335 26 193 2.66E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 SUPERFAMILY SSF47336 833 909 6.81E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 SUPERFAMILY SSF52151 514 730 1.07E-45 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Pfam PF00698 Acyl transferase domain 529 637 2.2E-21 T 12-10-2018 IPR014043 Acyl transferase TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 241 4.3E-61 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Gene3D G3DSA:3.30.70.3290 431 512 3.4E-60 T 12-10-2018 TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Gene3D G3DSA:3.40.366.10 513 638 3.4E-60 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Pfam PF00550 Phosphopantetheine attachment site 842 907 1.4E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Gene3D G3DSA:3.40.47.10 3 418 1.3E-146 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Gene3D G3DSA:1.10.1200.10 823 911 1.9E-25 T 12-10-2018 IPR036736 ACP-like superfamily TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 SUPERFAMILY SSF53901 12 410 1.92E-75 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 368 480 2.2E-20 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Gene3D G3DSA:3.40.366.10 644 748 1.2E-31 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 249 365 2.9E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 SMART SM00825 Beta-ketoacyl synthase 15 418 8.5E-146 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 528 745 4.6E-18 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 SMART SM00823 Phosphopantetheine attachment site 840 911 0.0036 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_04995 8e7bb2804b4ce9b0f520f04d59397bd4 911 Gene3D G3DSA:3.30.70.3290 749 793 1.2E-31 T 12-10-2018 TL08_21805 f1bfeae8a78d8e7e72a601983eca6341 384 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 11 380 5.8E-96 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TL08_21805 f1bfeae8a78d8e7e72a601983eca6341 384 PIRSF PIRSF006078 10 383 3.1E-99 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TL08_21805 f1bfeae8a78d8e7e72a601983eca6341 384 Gene3D G3DSA:3.40.50.10350 10 367 5.0E-100 T 12-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold TL08_21805 f1bfeae8a78d8e7e72a601983eca6341 384 Pfam PF02595 Glycerate kinase family 12 381 5.3E-105 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TL08_21805 f1bfeae8a78d8e7e72a601983eca6341 384 Gene3D G3DSA:3.90.1510.10 51 284 5.0E-100 T 12-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 TL08_21805 f1bfeae8a78d8e7e72a601983eca6341 384 SUPERFAMILY SSF110738 10 381 2.88E-92 T 12-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 Gene3D G3DSA:2.60.120.260 29 172 3.5E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 SUPERFAMILY SSF48208 275 747 1.55E-128 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 Gene3D G3DSA:2.60.40.290 754 860 1.3E-32 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 Pfam PF02018 Carbohydrate binding domain 35 156 1.3E-14 T 12-10-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 718 736 - T 12-10-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 SMART SM00637 759 859 2.0E-38 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 Gene3D G3DSA:2.60.40.10 183 272 2.6E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 Gene3D G3DSA:1.50.10.10 274 750 1.4E-188 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 SUPERFAMILY SSF81296 184 272 2.8E-19 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 SUPERFAMILY SSF49785 31 171 1.87E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 Pfam PF00759 Glycosyl hydrolase family 9 276 741 2.0E-101 T 12-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 Pfam PF02927 Cellulase N-terminal ig-like domain 183 265 1.9E-19 T 12-10-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 SUPERFAMILY SSF49384 755 859 2.79E-32 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 TL08_07570 3537bcdf7928785f86a6104dcd748f55 860 Pfam PF00553 Cellulose binding domain 759 859 3.2E-32 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TL08_09380 5512787c0666b6f2bfc7ef507446dc68 181 Gene3D G3DSA:3.90.950.20 15 179 1.7E-51 T 12-10-2018 IPR036653 CinA-like, C-terminal TL08_09380 5512787c0666b6f2bfc7ef507446dc68 181 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 32 172 5.7E-36 T 12-10-2018 IPR008136 CinA, C-terminal TL08_09380 5512787c0666b6f2bfc7ef507446dc68 181 SUPERFAMILY SSF142433 25 176 1.83E-43 T 12-10-2018 IPR036653 CinA-like, C-terminal TL08_09380 5512787c0666b6f2bfc7ef507446dc68 181 Pfam PF02464 Competence-damaged protein 27 174 3.2E-46 T 12-10-2018 IPR008136 CinA, C-terminal TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 SUPERFAMILY SSF52518 4 184 3.19E-48 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 Gene3D G3DSA:3.40.50.970 2 180 1.2E-54 T 12-10-2018 TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 SUPERFAMILY SSF52467 156 358 2.05E-41 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 SUPERFAMILY SSF52518 366 567 1.55E-51 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 Gene3D G3DSA:3.40.50.970 357 583 4.1E-55 T 12-10-2018 TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 171 3.4E-48 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 Gene3D G3DSA:3.40.50.1220 188 343 3.0E-41 T 12-10-2018 TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 329 6.4E-26 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TL08_15750 035de57ac13ecd1f89c9b0486db3c352 597 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 544 4.9E-28 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TL08_12395 63016b89e8541e2bfb479a70c794d6d4 128 Pfam PF01022 Bacterial regulatory protein, arsR family 45 87 8.6E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_12395 63016b89e8541e2bfb479a70c794d6d4 128 SUPERFAMILY SSF46785 26 115 2.15E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_12395 63016b89e8541e2bfb479a70c794d6d4 128 Gene3D G3DSA:1.10.10.10 18 121 2.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12395 63016b89e8541e2bfb479a70c794d6d4 128 SMART SM00418 35 113 3.5E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_12395 63016b89e8541e2bfb479a70c794d6d4 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 6.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_12395 63016b89e8541e2bfb479a70c794d6d4 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 6.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_12395 63016b89e8541e2bfb479a70c794d6d4 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 6.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_16055 5c11888798afaf80d29f81e400623a3d 491 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 429 443 1.8E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16055 5c11888798afaf80d29f81e400623a3d 491 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 443 459 1.8E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16055 5c11888798afaf80d29f81e400623a3d 491 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 459 471 1.8E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16055 5c11888798afaf80d29f81e400623a3d 491 Gene3D G3DSA:1.10.10.10 368 490 2.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16055 5c11888798afaf80d29f81e400623a3d 491 SMART SM00421 426 483 1.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16055 5c11888798afaf80d29f81e400623a3d 491 Pfam PF00196 Bacterial regulatory proteins, luxR family 433 481 2.0E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16055 5c11888798afaf80d29f81e400623a3d 491 SUPERFAMILY SSF46894 420 488 2.35E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_16740 3fdfd46c314765ce0ef27f48a94db069 311 PIRSF PIRSF000535 1 304 2.5E-68 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TL08_16740 3fdfd46c314765ce0ef27f48a94db069 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 242 255 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TL08_16740 3fdfd46c314765ce0ef27f48a94db069 311 Pfam PF00294 pfkB family carbohydrate kinase 12 280 4.7E-32 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_16740 3fdfd46c314765ce0ef27f48a94db069 311 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 4.9E-82 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TL08_16740 3fdfd46c314765ce0ef27f48a94db069 311 Gene3D G3DSA:3.40.1190.20 1 310 2.3E-95 T 12-10-2018 IPR029056 Ribokinase-like TL08_16740 3fdfd46c314765ce0ef27f48a94db069 311 SUPERFAMILY SSF53613 2 281 1.47E-54 T 12-10-2018 IPR029056 Ribokinase-like TL08_26400 31241d2775dd9f6ff2e9aa8b27f914fe 652 Gene3D G3DSA:2.120.10.30 365 475 2.8E-13 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_26400 31241d2775dd9f6ff2e9aa8b27f914fe 652 Gene3D G3DSA:2.120.10.30 277 358 3.4E-8 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_26400 31241d2775dd9f6ff2e9aa8b27f914fe 652 Gene3D G3DSA:2.120.10.30 197 276 1.0E-5 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_26400 31241d2775dd9f6ff2e9aa8b27f914fe 652 SUPERFAMILY SSF52833 61 209 3.14E-28 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_26400 31241d2775dd9f6ff2e9aa8b27f914fe 652 Pfam PF01436 NHL repeat 445 472 1.9E-4 T 12-10-2018 IPR001258 NHL repeat GO:0005515 TL08_26400 31241d2775dd9f6ff2e9aa8b27f914fe 652 Pfam PF00578 AhpC/TSA family 60 166 1.7E-8 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TL08_26400 31241d2775dd9f6ff2e9aa8b27f914fe 652 SUPERFAMILY SSF101898 200 509 3.92E-30 T 12-10-2018 TL08_26400 31241d2775dd9f6ff2e9aa8b27f914fe 652 Gene3D G3DSA:3.40.30.10 34 195 1.9E-30 T 12-10-2018 TL08_09625 3e5325f470a67c1a318f50392edef0f7 340 SMART SM00729 63 270 1.1E-30 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_09625 3e5325f470a67c1a318f50392edef0f7 340 Pfam PF04055 Radical SAM superfamily 70 230 1.8E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_09625 3e5325f470a67c1a318f50392edef0f7 340 TIGRFAM TIGR00433 bioB: biotin synthase 35 331 6.4E-98 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TL08_09625 3e5325f470a67c1a318f50392edef0f7 340 SUPERFAMILY SSF102114 24 321 9.94E-58 T 12-10-2018 TL08_09625 3e5325f470a67c1a318f50392edef0f7 340 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 241 329 7.8E-12 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TL08_09625 3e5325f470a67c1a318f50392edef0f7 340 Hamap MF_01694 Biotin synthase [bioB]. 11 334 35.909 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TL08_09625 3e5325f470a67c1a318f50392edef0f7 340 PIRSF PIRSF001619 6 339 1.3E-96 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TL08_09625 3e5325f470a67c1a318f50392edef0f7 340 Gene3D G3DSA:3.20.20.70 26 334 3.4E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_09625 3e5325f470a67c1a318f50392edef0f7 340 SMART SM00876 241 333 3.7E-26 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 333 345 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 SMART SM01086 747 836 2.5E-30 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 SUPERFAMILY SSF52540 198 477 6.73E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 242 356 8.5E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 605 623 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Gene3D G3DSA:3.40.50.300 382 498 1.3E-37 T 12-10-2018 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Gene3D G3DSA:1.10.1780.10 37 172 7.3E-26 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 3.7E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 575 593 3.7E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 682 696 3.7E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 620 638 3.7E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Pfam PF07724 AAA domain (Cdc48 subfamily) 570 741 3.0E-49 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 58 99 0.11 T 12-10-2018 IPR004176 Clp, N-terminal TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 125 172 1.6E-13 T 12-10-2018 IPR004176 Clp, N-terminal TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 747 827 3.3E-22 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Gene3D G3DSA:3.40.50.300 189 381 3.7E-67 T 12-10-2018 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Gene3D G3DSA:1.10.8.60 747 850 1.2E-24 T 12-10-2018 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Gene3D G3DSA:3.40.50.300 501 745 1.3E-91 T 12-10-2018 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 Pfam PF02151 UvrB/uvrC motif 455 488 9.3E-7 T 12-10-2018 IPR001943 UVR domain GO:0005515 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 SUPERFAMILY SSF52540 520 835 1.6E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 SUPERFAMILY SSF81923 41 170 1.41E-14 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 SMART SM00382 571 748 1.6E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_11105 65337d789b9ec822ac80b30b96cff2f8 852 SMART SM00382 237 382 3.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_16620 d8a5328f4993a0c46a8fa0a0ff3e2ee3 196 Pfam PF07883 Cupin domain 123 180 3.1E-10 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TL08_16620 d8a5328f4993a0c46a8fa0a0ff3e2ee3 196 Gene3D G3DSA:2.60.120.10 98 181 7.2E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_16620 d8a5328f4993a0c46a8fa0a0ff3e2ee3 196 SUPERFAMILY SSF47413 8 78 8.73E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_16620 d8a5328f4993a0c46a8fa0a0ff3e2ee3 196 SMART SM00530 18 73 7.7E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_16620 d8a5328f4993a0c46a8fa0a0ff3e2ee3 196 SUPERFAMILY SSF51182 70 179 5.09E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_16620 d8a5328f4993a0c46a8fa0a0ff3e2ee3 196 Gene3D G3DSA:1.10.260.40 14 84 1.6E-16 T 12-10-2018 TL08_16620 d8a5328f4993a0c46a8fa0a0ff3e2ee3 196 Pfam PF13560 Helix-turn-helix domain 16 72 2.4E-14 T 12-10-2018 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 PRINTS PR00315 GTP-binding elongation factor signature 28 41 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 PRINTS PR00315 GTP-binding elongation factor signature 78 86 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 PRINTS PR00315 GTP-binding elongation factor signature 98 108 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 PRINTS PR00315 GTP-binding elongation factor signature 150 159 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 PRINTS PR00315 GTP-binding elongation factor signature 114 125 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 SUPERFAMILY SSF54980 404 477 1.51E-10 T 12-10-2018 IPR035647 EF-G domain III/V-like TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 71 86 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 Gene3D G3DSA:3.40.50.300 27 389 1.4E-93 T 12-10-2018 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 Gene3D G3DSA:3.40.50.300 34 285 1.4E-93 T 12-10-2018 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 Pfam PF16658 Class II release factor RF3, C-terminal domain 398 523 6.2E-36 T 12-10-2018 IPR032090 Peptide chain release factor 3, C-terminal TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 SUPERFAMILY SSF52540 23 287 1.08E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 SUPERFAMILY SSF50447 272 399 6.56E-24 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 18 535 6.6E-157 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 17 537 47.247 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 Pfam PF00009 Elongation factor Tu GTP binding domain 26 287 9.3E-49 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 Gene3D G3DSA:3.30.70.3280 401 538 6.7E-37 T 12-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily TL08_10585 ba3f61243b983413d41d118c4c9f073c 540 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 30 161 1.6E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TL08_12310 0b721b53d0c174940a72642529fd9763 713 Pfam PF00199 Catalase 34 419 2.2E-172 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 Pfam PF06628 Catalase-related immune-responsive 451 513 9.2E-22 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 SUPERFAMILY SSF52317 545 660 1.79E-17 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_12310 0b721b53d0c174940a72642529fd9763 713 ProSitePatterns PS00438 Catalase proximal active site signature. 70 86 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 365 373 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 PRINTS PR00067 Catalase signature 151 169 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 PRINTS PR00067 Catalase signature 320 347 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 PRINTS PR00067 Catalase signature 111 129 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 PRINTS PR00067 Catalase signature 352 378 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 PRINTS PR00067 Catalase signature 47 70 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 PRINTS PR00067 Catalase signature 132 149 3.0E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 SMART SM01060 34 423 1.2E-261 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12310 0b721b53d0c174940a72642529fd9763 713 Gene3D G3DSA:3.40.50.880 541 712 3.3E-38 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_12310 0b721b53d0c174940a72642529fd9763 713 Gene3D G3DSA:2.40.180.10 2 445 1.6E-201 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 TL08_12310 0b721b53d0c174940a72642529fd9763 713 Gene3D G3DSA:1.20.1370.20 446 540 5.9E-31 T 12-10-2018 TL08_12310 0b721b53d0c174940a72642529fd9763 713 Pfam PF01965 DJ-1/PfpI family 548 658 7.0E-10 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TL08_12310 0b721b53d0c174940a72642529fd9763 713 PIRSF PIRSF038927 3 711 0.0 T 12-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 TL08_12310 0b721b53d0c174940a72642529fd9763 713 SUPERFAMILY SSF56634 17 539 2.88E-213 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_12800 6aa4497cd730b25b4d2f0518f8eaa904 187 Gene3D G3DSA:1.10.357.10 1 186 3.1E-51 T 12-10-2018 TL08_12800 6aa4497cd730b25b4d2f0518f8eaa904 187 SUPERFAMILY SSF46689 5 71 4.59E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_12800 6aa4497cd730b25b4d2f0518f8eaa904 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 54 1.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_12800 6aa4497cd730b25b4d2f0518f8eaa904 187 SUPERFAMILY SSF48498 79 183 2.71E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_26015 5a65d780413db26f1111c0c666cdc7ae 528 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 36 483 4.4E-156 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TL08_26015 5a65d780413db26f1111c0c666cdc7ae 528 SUPERFAMILY SSF53271 277 491 3.67E-68 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_26015 5a65d780413db26f1111c0c666cdc7ae 528 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 35 482 45.733 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TL08_26015 5a65d780413db26f1111c0c666cdc7ae 528 Pfam PF13522 Glutamine amidotransferase domain 93 236 8.0E-13 T 12-10-2018 TL08_26015 5a65d780413db26f1111c0c666cdc7ae 528 Gene3D G3DSA:3.40.50.2020 301 465 2.1E-144 T 12-10-2018 TL08_26015 5a65d780413db26f1111c0c666cdc7ae 528 PIRSF PIRSF000485 32 495 3.0E-157 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TL08_26015 5a65d780413db26f1111c0c666cdc7ae 528 Gene3D G3DSA:3.60.20.10 36 484 2.1E-144 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_26015 5a65d780413db26f1111c0c666cdc7ae 528 SUPERFAMILY SSF56235 36 294 1.29E-62 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_26015 5a65d780413db26f1111c0c666cdc7ae 528 Pfam PF00156 Phosphoribosyl transferase domain 305 412 1.3E-6 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 521 7.5E-82 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 SUPERFAMILY SSF54849 137 203 5.95E-19 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 Gene3D G3DSA:3.50.7.10 191 371 3.4E-210 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 Gene3D G3DSA:3.30.260.10 136 409 3.4E-210 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 SUPERFAMILY SSF48592 7 520 9.99E-68 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 SUPERFAMILY SSF52029 184 375 4.01E-75 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 Hamap MF_00600 60 kDa chaperonin [groL]. 2 534 38.85 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 Gene3D G3DSA:1.10.560.10 8 520 3.4E-210 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 PRINTS PR00298 60kDa chaperonin signature 27 53 3.3E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 PRINTS PR00298 60kDa chaperonin signature 83 110 3.3E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 PRINTS PR00298 60kDa chaperonin signature 267 290 3.3E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 PRINTS PR00298 60kDa chaperonin signature 397 418 3.3E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 PRINTS PR00298 60kDa chaperonin signature 349 374 3.3E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 ProSitePatterns PS00296 Chaperonins cpn60 signature. 404 415 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_24805 b9a63a5a0dd9a7d0a5be1ea224941dab 536 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 1.0E-224 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_19655 4333d75734cc8de266c0bfcf2152d794 541 Pfam PF00171 Aldehyde dehydrogenase family 28 445 6.0E-42 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_19655 4333d75734cc8de266c0bfcf2152d794 541 Gene3D G3DSA:3.40.605.10 53 536 6.0E-193 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_19655 4333d75734cc8de266c0bfcf2152d794 541 Gene3D G3DSA:3.40.309.10 278 471 6.0E-193 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_19655 4333d75734cc8de266c0bfcf2152d794 541 SUPERFAMILY SSF53720 30 533 1.57E-94 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_03565 10e7d4c02932a210712ac7d95b7b393b 207 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 150 204 1.2E-16 T 12-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type TL08_03565 10e7d4c02932a210712ac7d95b7b393b 207 Gene3D G3DSA:1.10.357.10 72 206 5.5E-34 T 12-10-2018 TL08_03565 10e7d4c02932a210712ac7d95b7b393b 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.3E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_03565 10e7d4c02932a210712ac7d95b7b393b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_03565 10e7d4c02932a210712ac7d95b7b393b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_03565 10e7d4c02932a210712ac7d95b7b393b 207 Gene3D G3DSA:1.10.10.60 9 64 9.7E-19 T 12-10-2018 TL08_03565 10e7d4c02932a210712ac7d95b7b393b 207 SUPERFAMILY SSF46689 10 73 5.08E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_03565 10e7d4c02932a210712ac7d95b7b393b 207 SUPERFAMILY SSF48498 81 203 3.47E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 Pfam PF07650 KH domain 37 109 1.1E-17 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 SUPERFAMILY SSF54814 2 105 5.76E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 Gene3D G3DSA:3.30.1140.32 108 208 7.9E-38 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 5.1E-36 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 7.3E-94 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 SMART SM00322 59 124 3.3E-7 T 12-10-2018 IPR004087 K Homology domain GO:0003676 TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 Gene3D G3DSA:3.30.300.20 17 106 5.4E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 SUPERFAMILY SSF54821 109 206 3.79E-35 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03015 db1903d1b7091d5f6f25b0226aa3b71a 275 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 37.884 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TL08_09145 07a58c4b2de5e371dd3ba68a3c01599c 343 Gene3D G3DSA:3.40.640.10 25 269 1.6E-47 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_09145 07a58c4b2de5e371dd3ba68a3c01599c 343 SUPERFAMILY SSF53383 12 342 3.36E-44 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_09145 07a58c4b2de5e371dd3ba68a3c01599c 343 Gene3D G3DSA:3.90.1150.10 15 337 1.6E-47 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_09145 07a58c4b2de5e371dd3ba68a3c01599c 343 Pfam PF00266 Aminotransferase class-V 15 290 1.4E-9 T 12-10-2018 IPR000192 Aminotransferase class V domain TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 49 376 2.4E-68 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 SUPERFAMILY SSF52279 426 666 4.32E-47 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 SUPERFAMILY SSF51445 27 425 2.0E-93 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 426 663 1.1E-45 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 Pfam PF14310 Fibronectin type III-like domain 724 793 2.6E-21 T 12-10-2018 IPR026891 Fibronectin type III-like domain TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 Gene3D G3DSA:3.20.20.300 36 391 2.5E-102 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 PRINTS PR00133 Glycosyl hydrolase family 3 signature 194 210 1.0E-18 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 PRINTS PR00133 Glycosyl hydrolase family 3 signature 125 141 1.0E-18 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 PRINTS PR00133 Glycosyl hydrolase family 3 signature 148 167 1.0E-18 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 PRINTS PR00133 Glycosyl hydrolase family 3 signature 225 241 1.0E-18 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 PRINTS PR00133 Glycosyl hydrolase family 3 signature 296 314 1.0E-18 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 Gene3D G3DSA:3.40.50.1700 412 664 1.9E-63 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 Gene3D G3DSA:2.60.40.10 695 809 6.3E-31 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_15500 5cbb3b614d749b0c7eeecc1f552ebf92 832 SMART SM01217 724 793 8.5E-30 T 12-10-2018 IPR026891 Fibronectin type III-like domain TL08_06780 316659ef0cc330f199592ae891036ab1 832 SUPERFAMILY SSF103025 440 738 6.44E-89 T 12-10-2018 TL08_06780 316659ef0cc330f199592ae891036ab1 832 SUPERFAMILY SSF51905 5 433 1.59E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06780 316659ef0cc330f199592ae891036ab1 832 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 728 818 9.5E-16 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TL08_06780 316659ef0cc330f199592ae891036ab1 832 SUPERFAMILY SSF101790 745 831 2.29E-20 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TL08_06780 316659ef0cc330f199592ae891036ab1 832 SUPERFAMILY SSF54373 226 350 4.71E-27 T 12-10-2018 TL08_06780 316659ef0cc330f199592ae891036ab1 832 Pfam PF16350 FAD dependent oxidoreductase central domain 390 445 2.2E-19 T 12-10-2018 IPR032503 FAD dependent oxidoreductase, central domain TL08_06780 316659ef0cc330f199592ae891036ab1 832 Gene3D G3DSA:3.50.50.60 7 406 1.3E-140 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06780 316659ef0cc330f199592ae891036ab1 832 Gene3D G3DSA:3.30.1360.120 440 710 2.9E-106 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TL08_06780 316659ef0cc330f199592ae891036ab1 832 Gene3D G3DSA:2.40.30.110 742 818 4.8E-27 T 12-10-2018 TL08_06780 316659ef0cc330f199592ae891036ab1 832 Pfam PF01571 Aminomethyltransferase folate-binding domain 447 721 2.5E-70 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TL08_06780 316659ef0cc330f199592ae891036ab1 832 Pfam PF01266 FAD dependent oxidoreductase 6 387 5.0E-48 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_06780 316659ef0cc330f199592ae891036ab1 832 Gene3D G3DSA:3.30.70.1400 516 735 2.9E-106 T 12-10-2018 TL08_06780 316659ef0cc330f199592ae891036ab1 832 Gene3D G3DSA:3.30.9.10 92 350 1.3E-140 T 12-10-2018 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 Pfam PF00067 Cytochrome P450 234 333 9.5E-18 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 Pfam PF00067 Cytochrome P450 167 227 3.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00359 B-class P450 signature 253 280 7.0E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00359 B-class P450 signature 116 131 7.0E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00359 B-class P450 signature 153 175 7.0E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00359 B-class P450 signature 235 246 7.0E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00359 B-class P450 signature 50 61 7.0E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00359 B-class P450 signature 99 115 7.0E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00359 B-class P450 signature 312 323 7.0E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00359 B-class P450 signature 303 312 7.0E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 Gene3D G3DSA:1.10.630.10 1 365 7.8E-129 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 305 314 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 SUPERFAMILY SSF48264 2 365 5.63E-90 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00385 P450 superfamily signature 200 217 1.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00385 P450 superfamily signature 235 246 1.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00385 P450 superfamily signature 312 323 1.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17125 4e8532101dbd65512b7385541c55cba2 368 PRINTS PR00385 P450 superfamily signature 303 312 1.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15645 5ea6a00386a0c086fea0622668d30e6e 311 Pfam PF06675 Protein of unknown function (DUF1177) 39 306 1.3E-131 T 12-10-2018 IPR009561 Protein of unknown function DUF1177 TL08_10755 f679f87f389a7582f3a0c0e080e526fc 161 Gene3D G3DSA:3.10.690.10 1 140 2.6E-47 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 TL08_10755 f679f87f389a7582f3a0c0e080e526fc 161 SUPERFAMILY SSF103256 3 137 3.14E-46 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 TL08_10755 f679f87f389a7582f3a0c0e080e526fc 161 Pfam PF02577 Bifunctional nuclease 7 128 5.6E-45 T 12-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 PRINTS PR00147 DNA photolyase signature 322 338 1.8E-21 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 PRINTS PR00147 DNA photolyase signature 138 154 1.8E-21 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 PRINTS PR00147 DNA photolyase signature 342 360 1.8E-21 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 PRINTS PR00147 DNA photolyase signature 381 395 1.8E-21 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 Gene3D G3DSA:3.40.50.620 8 206 9.5E-71 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 SUPERFAMILY SSF52425 4 176 5.76E-44 T 12-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 Pfam PF00875 DNA photolyase 8 162 7.5E-41 T 12-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 SUPERFAMILY SSF48173 193 464 4.84E-94 T 12-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 Gene3D G3DSA:1.10.579.10 291 467 7.1E-68 T 12-10-2018 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 Gene3D G3DSA:1.25.40.80 127 283 9.5E-71 T 12-10-2018 TL08_25100 d65d714b0003cac422691c4620ca9bdc 468 Pfam PF03441 FAD binding domain of DNA photolyase 270 462 6.3E-74 T 12-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 TL08_04140 70c61ee58171de683bd0a2a820b5d3bc 305 Pfam PF00892 EamA-like transporter family 15 147 2.5E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_04140 70c61ee58171de683bd0a2a820b5d3bc 305 Pfam PF00892 EamA-like transporter family 155 289 1.3E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_04140 70c61ee58171de683bd0a2a820b5d3bc 305 SUPERFAMILY SSF103481 210 291 2.48E-7 T 12-10-2018 TL08_04140 70c61ee58171de683bd0a2a820b5d3bc 305 SUPERFAMILY SSF103481 48 151 2.48E-11 T 12-10-2018 TL08_09980 eab2a7bc6172be9e7e3567b637e53783 395 Gene3D G3DSA:3.90.1150.10 34 389 4.4E-91 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_09980 eab2a7bc6172be9e7e3567b637e53783 395 Gene3D G3DSA:3.40.640.10 43 292 4.4E-91 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_09980 eab2a7bc6172be9e7e3567b637e53783 395 SUPERFAMILY SSF53383 36 394 3.79E-75 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_09980 eab2a7bc6172be9e7e3567b637e53783 395 Pfam PF00266 Aminotransferase class-V 66 382 1.8E-28 T 12-10-2018 IPR000192 Aminotransferase class V domain TL08_09980 eab2a7bc6172be9e7e3567b637e53783 395 PIRSF PIRSF000524 29 395 2.3E-66 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 Gene3D G3DSA:1.20.970.10 3 71 8.8E-24 T 12-10-2018 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 Gene3D G3DSA:3.40.1030.10 81 326 3.6E-133 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 114 129 - T 12-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 SUPERFAMILY SSF52418 76 323 1.96E-80 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 Pfam PF00591 Glycosyl transferase family, a/b domain 81 306 3.4E-34 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 SMART SM00941 341 415 7.9E-27 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 PIRSF PIRSF000478 4 430 1.4E-150 T 12-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 Gene3D G3DSA:3.90.1170.30 327 414 3.6E-133 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 SUPERFAMILY SSF47648 6 73 1.1E-20 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 Pfam PF02885 Glycosyl transferase family, helical bundle domain 8 70 4.2E-18 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 8 414 5.4E-164 T 12-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 SUPERFAMILY SSF54680 328 419 4.97E-23 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_24395 20728878bf8811493cec0c0e2cb359fb 437 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 342 414 9.6E-19 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_11505 d6c8b0bf22435221b7b003942c8c2f18 280 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 92 105 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11505 d6c8b0bf22435221b7b003942c8c2f18 280 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 3 277 33.546 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11505 d6c8b0bf22435221b7b003942c8c2f18 280 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 5 267 4.9E-79 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11505 d6c8b0bf22435221b7b003942c8c2f18 280 Gene3D G3DSA:3.20.20.70 4 278 1.5E-87 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_11505 d6c8b0bf22435221b7b003942c8c2f18 280 SUPERFAMILY SSF51366 5 273 1.37E-59 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TL08_11505 d6c8b0bf22435221b7b003942c8c2f18 280 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 18 266 1.2E-35 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_11505 d6c8b0bf22435221b7b003942c8c2f18 280 SMART SM00934 18 267 7.4E-35 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_22210 5b914c46104dd8cd71b5262bac9d5ccf 322 Gene3D G3DSA:3.40.366.10 1 264 2.6E-76 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_22210 5b914c46104dd8cd71b5262bac9d5ccf 322 Gene3D G3DSA:3.30.70.250 111 174 2.6E-76 T 12-10-2018 TL08_22210 5b914c46104dd8cd71b5262bac9d5ccf 322 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 49 290 5.9E-14 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_22210 5b914c46104dd8cd71b5262bac9d5ccf 322 SUPERFAMILY SSF52151 1 288 2.88E-53 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_22210 5b914c46104dd8cd71b5262bac9d5ccf 322 Pfam PF00698 Acyl transferase domain 20 267 3.7E-19 T 12-10-2018 IPR014043 Acyl transferase TL08_22210 5b914c46104dd8cd71b5262bac9d5ccf 322 SUPERFAMILY SSF55048 113 162 3.27E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_23520 ccf943a2b3638ea9fb7011822d51783a 174 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 9 156 2.7E-61 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TL08_23520 ccf943a2b3638ea9fb7011822d51783a 174 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 9 160 30.836 T 12-10-2018 IPR033747 Class I PurE TL08_23520 ccf943a2b3638ea9fb7011822d51783a 174 PIRSF PIRSF001338 4 171 1.1E-65 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 TL08_23520 ccf943a2b3638ea9fb7011822d51783a 174 SMART SM01001 7 156 1.2E-87 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TL08_23520 ccf943a2b3638ea9fb7011822d51783a 174 SUPERFAMILY SSF52255 7 168 7.72E-62 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TL08_23520 ccf943a2b3638ea9fb7011822d51783a 174 Pfam PF00731 AIR carboxylase 9 151 3.5E-62 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TL08_23520 ccf943a2b3638ea9fb7011822d51783a 174 Gene3D G3DSA:3.40.50.7700 1 173 3.3E-70 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TL08_21465 0eac7e019e17b81d8868cb2ff1e3b010 277 Gene3D G3DSA:3.40.50.150 35 201 6.8E-14 T 12-10-2018 TL08_21465 0eac7e019e17b81d8868cb2ff1e3b010 277 SUPERFAMILY SSF53335 57 182 2.36E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_21465 0eac7e019e17b81d8868cb2ff1e3b010 277 Pfam PF13489 Methyltransferase domain 53 175 5.4E-7 T 12-10-2018 TL08_17760 dfe4b4c675a1740eb7012ce7519e1999 206 SMART SM00382 27 206 3.0E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17760 dfe4b4c675a1740eb7012ce7519e1999 206 SUPERFAMILY SSF52540 2 202 5.33E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17760 dfe4b4c675a1740eb7012ce7519e1999 206 Pfam PF00005 ABC transporter 18 158 1.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_17760 dfe4b4c675a1740eb7012ce7519e1999 206 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_17760 dfe4b4c675a1740eb7012ce7519e1999 206 Gene3D G3DSA:3.40.50.300 1 205 2.1E-50 T 12-10-2018 TL08_17585 cd34c0cb7b6b1699af0b17f6a45763c7 244 SUPERFAMILY SSF53335 31 206 1.24E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_17585 cd34c0cb7b6b1699af0b17f6a45763c7 244 Gene3D G3DSA:3.40.50.150 30 191 2.4E-23 T 12-10-2018 TL08_17585 cd34c0cb7b6b1699af0b17f6a45763c7 244 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 48 135 5.3E-7 T 12-10-2018 TL08_08075 e4d481d67c95ad0fb54ddaf38c8d6de2 306 SUPERFAMILY SSF53927 4 273 4.51E-80 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TL08_08075 e4d481d67c95ad0fb54ddaf38c8d6de2 306 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 273 34.686 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TL08_08075 e4d481d67c95ad0fb54ddaf38c8d6de2 306 PIRSF PIRSF015626 1 277 2.3E-87 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TL08_08075 e4d481d67c95ad0fb54ddaf38c8d6de2 306 Gene3D G3DSA:3.10.20.10 28 120 2.3E-6 T 12-10-2018 TL08_08075 e4d481d67c95ad0fb54ddaf38c8d6de2 306 Gene3D G3DSA:3.40.140.10 126 280 6.1E-55 T 12-10-2018 TL08_08075 e4d481d67c95ad0fb54ddaf38c8d6de2 306 Pfam PF02634 FdhD/NarQ family 26 272 1.6E-84 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TL08_08075 e4d481d67c95ad0fb54ddaf38c8d6de2 306 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 272 4.0E-51 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TL08_05735 12f16fd6a0b5d2a3c07558135d9017dd 174 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 8 75 1.7E-7 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_05735 12f16fd6a0b5d2a3c07558135d9017dd 174 SUPERFAMILY SSF56214 8 81 3.84E-8 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_05735 12f16fd6a0b5d2a3c07558135d9017dd 174 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 11 80 4.0E-4 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TL08_05735 12f16fd6a0b5d2a3c07558135d9017dd 174 Gene3D G3DSA:3.90.470.20 4 122 6.5E-9 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_15455 c6168da0cf0d2423aa4f826e3ad922f7 375 Gene3D G3DSA:3.40.50.720 10 318 3.9E-81 T 12-10-2018 TL08_15455 c6168da0cf0d2423aa4f826e3ad922f7 375 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 250 4.4E-13 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TL08_15455 c6168da0cf0d2423aa4f826e3ad922f7 375 Gene3D G3DSA:3.30.360.10 133 340 3.9E-81 T 12-10-2018 TL08_15455 c6168da0cf0d2423aa4f826e3ad922f7 375 SUPERFAMILY SSF55347 137 273 1.34E-27 T 12-10-2018 TL08_15455 c6168da0cf0d2423aa4f826e3ad922f7 375 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 118 1.9E-19 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_15455 c6168da0cf0d2423aa4f826e3ad922f7 375 SUPERFAMILY SSF51735 4 162 1.35E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14875 c62af73503482a30f11acccc4f35286d 1083 Gene3D G3DSA:3.30.559.30 233 486 4.0E-26 T 12-10-2018 TL08_14875 c62af73503482a30f11acccc4f35286d 1083 SUPERFAMILY SSF56801 479 1015 1.44E-131 T 12-10-2018 TL08_14875 c62af73503482a30f11acccc4f35286d 1083 SUPERFAMILY SSF52777 48 225 2.22E-32 T 12-10-2018 TL08_14875 c62af73503482a30f11acccc4f35286d 1083 Pfam PF00550 Phosphopantetheine attachment site 1004 1069 1.2E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14875 c62af73503482a30f11acccc4f35286d 1083 ProSitePatterns PS00455 Putative AMP-binding domain signature. 634 645 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_14875 c62af73503482a30f11acccc4f35286d 1083 SMART SM00823 Phosphopantetheine attachment site 1002 1073 4.6E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14875 c62af73503482a30f11acccc4f35286d 1083 Gene3D G3DSA:3.30.559.10 44 232 2.5E-33 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_14875 c62af73503482a30f11acccc4f35286d 1083 Pfam PF00501 AMP-binding enzyme 501 892 5.0E-83 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_14875 c62af73503482a30f11acccc4f35286d 1083 Gene3D G3DSA:3.30.300.30 886 993 7.7E-21 T 12-10-2018 TL08_14875 c62af73503482a30f11acccc4f35286d 1083 Gene3D G3DSA:3.40.50.12780 491 884 3.1E-115 T 12-10-2018 TL08_14875 c62af73503482a30f11acccc4f35286d 1083 Gene3D G3DSA:1.10.1200.10 994 1074 8.5E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14875 c62af73503482a30f11acccc4f35286d 1083 SUPERFAMILY SSF47336 996 1070 2.88E-12 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14875 c62af73503482a30f11acccc4f35286d 1083 SUPERFAMILY SSF52777 233 464 2.67E-27 T 12-10-2018 TL08_14875 c62af73503482a30f11acccc4f35286d 1083 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 521 916 7.3E-109 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_14875 c62af73503482a30f11acccc4f35286d 1083 Pfam PF00668 Condensation domain 48 468 7.0E-31 T 12-10-2018 IPR001242 Condensation domain TL08_15135 5c79fc916cfc887c51a11994b3612375 158 SUPERFAMILY SSF55961 8 157 5.15E-33 T 12-10-2018 TL08_15135 5c79fc916cfc887c51a11994b3612375 158 Gene3D G3DSA:3.30.530.20 2 157 1.2E-38 T 12-10-2018 IPR023393 START-like domain superfamily TL08_15135 5c79fc916cfc887c51a11994b3612375 158 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 133 6.7E-15 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 SUPERFAMILY SSF55785 147 273 1.34E-24 T 12-10-2018 IPR035965 PAS domain superfamily TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 SMART SM00052 457 708 7.6E-113 T 12-10-2018 IPR001633 EAL domain TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 283 445 2.0E-33 T 12-10-2018 IPR000160 GGDEF domain TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 156 282 4.0E-24 T 12-10-2018 IPR000014 PAS domain TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 SMART SM00086 233 275 1.8E-4 T 12-10-2018 IPR001610 PAC motif TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 Pfam PF00563 EAL domain 466 703 1.6E-70 T 12-10-2018 IPR001633 EAL domain TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 Gene3D G3DSA:3.30.70.270 280 459 1.7E-50 T 12-10-2018 TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 SUPERFAMILY SSF141868 466 714 3.4E-81 T 12-10-2018 IPR035919 EAL domain superfamily TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 Pfam PF13426 PAS domain 173 274 2.3E-11 T 12-10-2018 IPR000014 PAS domain TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 Pfam PF00990 Diguanylate cyclase, GGDEF domain 286 442 1.6E-38 T 12-10-2018 IPR000160 GGDEF domain TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 SMART SM00091 160 226 5.7E-8 T 12-10-2018 IPR000014 PAS domain TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 Gene3D G3DSA:3.30.450.20 146 273 2.2E-25 T 12-10-2018 TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 SMART SM00267 275 447 1.1E-54 T 12-10-2018 IPR000160 GGDEF domain TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 SUPERFAMILY SSF55073 291 449 1.39E-40 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_26030 55fcb89462847c5e90c24e4c8ba5f731 719 Gene3D G3DSA:3.20.20.450 460 719 1.1E-96 T 12-10-2018 IPR035919 EAL domain superfamily TL08_17680 a9dc23e7b66de3cd2bb20cc3b2e43c1f 344 Gene3D G3DSA:3.40.50.2300 87 336 3.6E-73 T 12-10-2018 TL08_17680 a9dc23e7b66de3cd2bb20cc3b2e43c1f 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 9.4E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_17680 a9dc23e7b66de3cd2bb20cc3b2e43c1f 344 SUPERFAMILY SSF53822 86 344 5.98E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_17680 a9dc23e7b66de3cd2bb20cc3b2e43c1f 344 Pfam PF13377 Periplasmic binding protein-like domain 185 344 3.9E-37 T 12-10-2018 TL08_17680 a9dc23e7b66de3cd2bb20cc3b2e43c1f 344 Gene3D G3DSA:1.10.260.40 9 69 3.6E-23 T 12-10-2018 TL08_17680 a9dc23e7b66de3cd2bb20cc3b2e43c1f 344 SMART SM00354 12 82 1.1E-23 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_17680 a9dc23e7b66de3cd2bb20cc3b2e43c1f 344 Gene3D G3DSA:3.40.50.2300 176 338 3.6E-73 T 12-10-2018 TL08_17680 a9dc23e7b66de3cd2bb20cc3b2e43c1f 344 SUPERFAMILY SSF47413 12 69 2.36E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_11375 b39b4a9af567967e16e7d9de3615387a 406 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 39 403 25.242 T 12-10-2018 IPR003770 Endolytic murein transglycosylase TL08_11375 b39b4a9af567967e16e7d9de3615387a 406 Pfam PF02618 YceG-like family 79 395 1.1E-53 T 12-10-2018 IPR003770 Endolytic murein transglycosylase TL08_11375 b39b4a9af567967e16e7d9de3615387a 406 Gene3D G3DSA:1.10.8.1150 74 144 4.1E-8 T 12-10-2018 TL08_11375 b39b4a9af567967e16e7d9de3615387a 406 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 44 394 9.9E-35 T 12-10-2018 IPR003770 Endolytic murein transglycosylase TL08_03180 ce5427a94927d6f476a20cf989320481 306 Gene3D G3DSA:3.40.190.10 165 266 1.2E-30 T 12-10-2018 TL08_03180 ce5427a94927d6f476a20cf989320481 306 Gene3D G3DSA:1.10.10.10 1 86 8.3E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03180 ce5427a94927d6f476a20cf989320481 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_03180 ce5427a94927d6f476a20cf989320481 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_03180 ce5427a94927d6f476a20cf989320481 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.3E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_03180 ce5427a94927d6f476a20cf989320481 306 SUPERFAMILY SSF46785 2 112 8.39E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_03180 ce5427a94927d6f476a20cf989320481 306 Pfam PF03466 LysR substrate binding domain 88 290 5.8E-31 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_03180 ce5427a94927d6f476a20cf989320481 306 SUPERFAMILY SSF53850 91 293 4.71E-28 T 12-10-2018 TL08_03180 ce5427a94927d6f476a20cf989320481 306 Gene3D G3DSA:3.40.190.10 92 274 1.2E-30 T 12-10-2018 TL08_03180 ce5427a94927d6f476a20cf989320481 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.1E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.6E-38 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.6E-38 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.6E-38 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 Gene3D G3DSA:1.10.720.90 2 55 2.9E-19 T 12-10-2018 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 Gene3D G3DSA:1.10.1900.20 56 120 2.8E-27 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 2.0E-21 T 12-10-2018 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 114 3.0E-44 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 Pfam PF00453 Ribosomal protein L20 3 108 7.1E-45 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.504 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_18180 7ae088662d6e9d164a8aa7f4916b7360 127 SUPERFAMILY SSF74731 3 117 4.97E-46 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_10830 669436dd9585327a84a4c9db53952cd4 655 ProSitePatterns PS00080 Multicopper oxidases signature 2. 618 629 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 TL08_10830 669436dd9585327a84a4c9db53952cd4 655 Gene3D G3DSA:2.60.40.420 253 429 1.1E-52 T 12-10-2018 IPR008972 Cupredoxin TL08_10830 669436dd9585327a84a4c9db53952cd4 655 Gene3D G3DSA:2.60.40.420 431 655 1.7E-52 T 12-10-2018 IPR008972 Cupredoxin TL08_10830 669436dd9585327a84a4c9db53952cd4 655 ProSitePatterns PS00079 Multicopper oxidases signature 1. 613 633 - T 12-10-2018 IPR033138 Multicopper oxidases, conserved site TL08_10830 669436dd9585327a84a4c9db53952cd4 655 Gene3D G3DSA:2.60.40.420 68 252 2.7E-52 T 12-10-2018 IPR008972 Cupredoxin TL08_10830 669436dd9585327a84a4c9db53952cd4 655 SUPERFAMILY SSF49503 299 636 2.01E-23 T 12-10-2018 IPR008972 Cupredoxin TL08_10830 669436dd9585327a84a4c9db53952cd4 655 SUPERFAMILY SSF49503 75 256 1.79E-20 T 12-10-2018 IPR008972 Cupredoxin TL08_10830 669436dd9585327a84a4c9db53952cd4 655 Pfam PF07731 Multicopper oxidase 506 638 8.1E-22 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 TL08_10830 669436dd9585327a84a4c9db53952cd4 655 Pfam PF07732 Multicopper oxidase 113 147 9.6E-5 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TL08_10830 669436dd9585327a84a4c9db53952cd4 655 Pfam PF07732 Multicopper oxidase 190 255 5.1E-6 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TL08_10830 669436dd9585327a84a4c9db53952cd4 655 SUPERFAMILY SSF49503 260 386 7.54E-12 T 12-10-2018 IPR008972 Cupredoxin TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 266 0.0011 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 532 564 1.0E-4 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 Pfam PF00005 ABC transporter 24 180 2.0E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 Gene3D G3DSA:3.40.50.300 309 592 3.0E-75 T 12-10-2018 TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 Gene3D G3DSA:3.40.50.300 1 308 1.8E-81 T 12-10-2018 TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 SUPERFAMILY SSF52540 3 252 7.31E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 Pfam PF00005 ABC transporter 331 481 3.7E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 SMART SM00382 339 530 5.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 SMART SM00382 32 230 1.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 SUPERFAMILY SSF52540 321 552 1.42E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13085 e3b8b3aab96b4f72bae94ad50ae89f30 647 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 SMART SM00382 312 440 3.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 Gene3D G3DSA:1.10.8.60 446 516 4.7E-25 T 12-10-2018 TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 Gene3D G3DSA:3.40.50.300 268 444 2.8E-52 T 12-10-2018 TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 SMART SM00760 524 593 5.6E-35 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 345 359 1.4E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 377 391 1.4E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 313 333 1.4E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 574 593 1.4E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 411 438 1.4E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 ProSitePatterns PS01008 DnaA protein signature. 574 593 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 615 31.778 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 527 593 2.5E-28 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 SUPERFAMILY SSF48295 511 616 2.56E-35 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 SUPERFAMILY SSF52540 279 491 1.19E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 Pfam PF00308 Bacterial dnaA protein 280 497 7.7E-102 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 Gene3D G3DSA:1.10.1750.10 520 620 2.1E-36 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TL08_00005 74fc2ddad56471ce74264a30bc9dfc76 620 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 268 614 2.2E-149 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 Gene3D G3DSA:1.10.1200.190 173 380 8.3E-146 T 12-10-2018 TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 Gene3D G3DSA:3.30.70.2100 574 641 4.6E-30 T 12-10-2018 TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 Gene3D G3DSA:1.10.10.1620 666 713 5.6E-20 T 12-10-2018 TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 SUPERFAMILY SSF51905 101 711 1.62E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 SUPERFAMILY SSF54373 569 658 1.57E-18 T 12-10-2018 TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 Gene3D G3DSA:1.10.10.1790 487 532 2.3E-24 T 12-10-2018 TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 Gene3D G3DSA:3.50.50.60 102 406 8.3E-146 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 Pfam PF01593 Flavin containing amine oxidoreductase 112 501 4.6E-31 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 Pfam PF01593 Flavin containing amine oxidoreductase 572 710 8.0E-20 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 Gene3D G3DSA:1.10.405.10 279 369 8.3E-146 T 12-10-2018 TL08_08465 3def938747c3e1e0e44a6cb9fa101144 716 Gene3D G3DSA:3.30.160.490 242 278 8.3E-146 T 12-10-2018 TL08_13985 6ff69f4758a3aa2c4899b03e87e9156f 609 Gene3D G3DSA:1.20.1560.10 12 336 1.3E-57 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_13985 6ff69f4758a3aa2c4899b03e87e9156f 609 Pfam PF00664 ABC transporter transmembrane region 39 308 3.0E-30 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_13985 6ff69f4758a3aa2c4899b03e87e9156f 609 SUPERFAMILY SSF52540 343 585 6.76E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13985 6ff69f4758a3aa2c4899b03e87e9156f 609 SUPERFAMILY SSF90123 24 331 2.09E-59 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_13985 6ff69f4758a3aa2c4899b03e87e9156f 609 Gene3D G3DSA:3.40.50.300 344 589 2.7E-69 T 12-10-2018 TL08_13985 6ff69f4758a3aa2c4899b03e87e9156f 609 SMART SM00382 376 561 7.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13985 6ff69f4758a3aa2c4899b03e87e9156f 609 Pfam PF00005 ABC transporter 367 515 2.6E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05890 6a8fea458f7791295075fbd98c74759f 546 Gene3D G3DSA:3.50.50.60 17 198 1.8E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05890 6a8fea458f7791295075fbd98c74759f 546 Gene3D G3DSA:3.50.50.60 219 353 1.3E-6 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05890 6a8fea458f7791295075fbd98c74759f 546 Pfam PF00732 GMC oxidoreductase 24 296 2.1E-13 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TL08_05890 6a8fea458f7791295075fbd98c74759f 546 Pfam PF05199 GMC oxidoreductase 395 515 2.2E-27 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 TL08_05890 6a8fea458f7791295075fbd98c74759f 546 SUPERFAMILY SSF51905 20 522 8.19E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05890 6a8fea458f7791295075fbd98c74759f 546 Gene3D G3DSA:3.50.50.60 434 527 2.5E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_13640 99738971f2b429c710682224321c5377 1404 SUPERFAMILY SSF48208 316 788 6.32E-24 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_13640 99738971f2b429c710682224321c5377 1404 SUPERFAMILY SSF49299 1040 1098 2.94E-5 T 12-10-2018 IPR035986 PKD domain superfamily TL08_13640 99738971f2b429c710682224321c5377 1404 Gene3D G3DSA:1.50.10.10 386 624 2.3E-11 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_13640 99738971f2b429c710682224321c5377 1404 Gene3D G3DSA:2.60.120.260 1100 1250 5.3E-34 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_13640 99738971f2b429c710682224321c5377 1404 Gene3D G3DSA:2.60.120.260 852 996 4.9E-23 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_13640 99738971f2b429c710682224321c5377 1404 Pfam PF07532 Bacterial Ig-like domain (group 4) 1337 1391 2.8E-15 T 12-10-2018 IPR011081 Bacterial Ig-related TL08_13640 99738971f2b429c710682224321c5377 1404 Pfam PF07532 Bacterial Ig-like domain (group 4) 1256 1310 8.0E-5 T 12-10-2018 IPR011081 Bacterial Ig-related TL08_13640 99738971f2b429c710682224321c5377 1404 Gene3D G3DSA:2.60.40.10 1012 1099 1.2E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_13640 99738971f2b429c710682224321c5377 1404 SUPERFAMILY SSF49785 1101 1238 7.83E-6 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_13640 99738971f2b429c710682224321c5377 1404 Pfam PF00754 F5/8 type C domain 865 989 2.9E-10 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain TL08_13640 99738971f2b429c710682224321c5377 1404 SUPERFAMILY SSF49785 854 996 2.21E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_00165 0adb22a7e81f5c9156345c1c67dceae6 426 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 157 203 1.9E-4 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 TL08_00165 0adb22a7e81f5c9156345c1c67dceae6 426 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 260 298 1.7E-4 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 TL08_00165 0adb22a7e81f5c9156345c1c67dceae6 426 Gene3D G3DSA:3.40.50.1820 66 415 1.0E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_00165 0adb22a7e81f5c9156345c1c67dceae6 426 SUPERFAMILY SSF53474 101 405 1.69E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06885 fcf6517410c4ff59c311c0f6a1c640ea 300 SUPERFAMILY SSF53335 45 277 2.61E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_06885 fcf6517410c4ff59c311c0f6a1c640ea 300 Pfam PF13649 Methyltransferase domain 69 165 5.0E-18 T 12-10-2018 TL08_06885 fcf6517410c4ff59c311c0f6a1c640ea 300 Gene3D G3DSA:3.40.50.150 40 271 1.9E-34 T 12-10-2018 TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 SUPERFAMILY SSF51445 174 503 2.11E-69 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 SUPERFAMILY SSF55545 47 169 1.2E-14 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 PRINTS PR00738 Glycosyl hydrolase family 20 signature 242 259 5.4E-17 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 PRINTS PR00738 Glycosyl hydrolase family 20 signature 317 330 5.4E-17 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 PRINTS PR00738 Glycosyl hydrolase family 20 signature 130 150 5.4E-17 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 PRINTS PR00738 Glycosyl hydrolase family 20 signature 295 313 5.4E-17 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 Gene3D G3DSA:2.60.120.260 517 653 6.4E-20 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 48 168 1.8E-16 T 12-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 175 437 1.8E-49 T 12-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 SUPERFAMILY SSF49785 534 637 1.49E-16 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 Gene3D G3DSA:3.20.20.80 172 514 1.4E-74 T 12-10-2018 TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 Pfam PF00754 F5/8 type C domain 533 635 6.1E-15 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain TL08_16755 3e23bb775058ab879a9ac3325ae8e04b 654 Gene3D G3DSA:3.30.379.10 33 165 2.0E-24 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 TL08_14460 a5042e5bd59524816b5179631fd7aa1c 230 SUPERFAMILY SSF48498 75 211 1.11E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_14460 a5042e5bd59524816b5179631fd7aa1c 230 Gene3D G3DSA:1.10.10.60 2 64 1.3E-18 T 12-10-2018 TL08_14460 a5042e5bd59524816b5179631fd7aa1c 230 Gene3D G3DSA:1.10.357.10 67 218 3.7E-24 T 12-10-2018 TL08_14460 a5042e5bd59524816b5179631fd7aa1c 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 53 1.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14460 a5042e5bd59524816b5179631fd7aa1c 230 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 71 209 2.3E-13 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 TL08_14460 a5042e5bd59524816b5179631fd7aa1c 230 SUPERFAMILY SSF46689 6 66 1.03E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_17280 47c1ffb03284aa364e372cf09144fd58 240 Pfam PF01551 Peptidase family M23 134 228 3.0E-30 T 12-10-2018 IPR016047 Peptidase M23 TL08_17280 47c1ffb03284aa364e372cf09144fd58 240 SUPERFAMILY SSF51261 81 232 1.26E-46 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_17280 47c1ffb03284aa364e372cf09144fd58 240 Gene3D G3DSA:2.70.70.10 87 235 1.2E-42 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_25080 a8017907bfeef38326ecbf0a8c101795 90 Gene3D G3DSA:1.10.260.40 12 75 4.8E-20 T 12-10-2018 TL08_25080 a8017907bfeef38326ecbf0a8c101795 90 SMART SM00530 15 70 9.6E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_25080 a8017907bfeef38326ecbf0a8c101795 90 SUPERFAMILY SSF47413 12 74 3.38E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_25080 a8017907bfeef38326ecbf0a8c101795 90 Pfam PF01381 Helix-turn-helix 16 67 1.7E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 SUPERFAMILY SSF46894 146 214 5.1E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 6.6E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 SMART SM00448 3 116 4.2E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 SUPERFAMILY SSF52172 2 134 2.99E-34 T 12-10-2018 IPR011006 CheY-like superfamily TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 Gene3D G3DSA:3.40.50.12740 3 214 9.8E-72 T 12-10-2018 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 SMART SM00421 151 208 5.1E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20910 a63cf825e8a1d75d6f84d0831fa013af 218 Pfam PF00072 Response regulator receiver domain 5 116 3.4E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_07440 8d61b1c6122323088a6c754286b89cdc 215 SUPERFAMILY SSF101473 4 205 3.27E-50 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TL08_07440 8d61b1c6122323088a6c754286b89cdc 215 Pfam PF02734 DAK2 domain 32 205 4.7E-50 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TL08_07440 8d61b1c6122323088a6c754286b89cdc 215 SMART SM01120 32 206 1.5E-66 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TL08_07440 8d61b1c6122323088a6c754286b89cdc 215 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 15 205 2.1E-66 T 12-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 TL08_07440 8d61b1c6122323088a6c754286b89cdc 215 Gene3D G3DSA:1.25.40.340 3 209 3.3E-58 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TL08_06690 01e1c8f910461300d29bfc71a30d80b9 364 Gene3D G3DSA:3.40.50.620 1 211 7.3E-73 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_06690 01e1c8f910461300d29bfc71a30d80b9 364 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 359 3.2E-85 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TL08_06690 01e1c8f910461300d29bfc71a30d80b9 364 SUPERFAMILY SSF52402 1 244 1.08E-45 T 12-10-2018 TL08_06690 01e1c8f910461300d29bfc71a30d80b9 364 Gene3D G3DSA:2.30.30.280 213 278 1.7E-9 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TL08_06690 01e1c8f910461300d29bfc71a30d80b9 364 Gene3D G3DSA:2.40.30.10 279 364 1.8E-9 T 12-10-2018 TL08_06690 01e1c8f910461300d29bfc71a30d80b9 364 Pfam PF03054 tRNA methyl transferase 1 359 1.1E-111 T 12-10-2018 TL08_06690 01e1c8f910461300d29bfc71a30d80b9 364 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 361 36.005 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TL08_20850 2e366ce4027e80ee364f8d4eda7a03a6 691 Gene3D G3DSA:3.40.50.1820 426 684 2.7E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_20850 2e366ce4027e80ee364f8d4eda7a03a6 691 SUPERFAMILY SSF53474 429 679 2.44E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_20850 2e366ce4027e80ee364f8d4eda7a03a6 691 Pfam PF07676 WD40-like Beta Propeller Repeat 74 107 0.14 T 12-10-2018 IPR011659 WD40-like Beta Propeller TL08_20850 2e366ce4027e80ee364f8d4eda7a03a6 691 Gene3D G3DSA:2.120.10.30 5 149 1.4E-5 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_20850 2e366ce4027e80ee364f8d4eda7a03a6 691 Gene3D G3DSA:2.120.10.30 196 405 3.5E-30 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_20850 2e366ce4027e80ee364f8d4eda7a03a6 691 SUPERFAMILY SSF82171 33 394 1.57E-35 T 12-10-2018 TL08_20850 2e366ce4027e80ee364f8d4eda7a03a6 691 Pfam PF00326 Prolyl oligopeptidase family 473 679 2.1E-42 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_24850 a068e4208a7c460c31b672c2ca6830e4 369 SUPERFAMILY SSF53474 58 347 6.57E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_24850 a068e4208a7c460c31b672c2ca6830e4 369 Gene3D G3DSA:3.40.50.1820 53 357 3.3E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_24850 a068e4208a7c460c31b672c2ca6830e4 369 Pfam PF12697 Alpha/beta hydrolase family 83 342 1.0E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_26000 a6dfba27e9cf66e385482b2791dd9aca 287 SMART SM00530 15 68 1.5E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_26000 a6dfba27e9cf66e385482b2791dd9aca 287 SUPERFAMILY SSF47413 9 63 1.05E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_26000 a6dfba27e9cf66e385482b2791dd9aca 287 Gene3D G3DSA:1.10.260.40 9 68 8.2E-10 T 12-10-2018 TL08_26000 a6dfba27e9cf66e385482b2791dd9aca 287 Pfam PF13560 Helix-turn-helix domain 12 71 5.2E-11 T 12-10-2018 TL08_02095 6deafdefe8d346163e3fbea9c9300231 277 SUPERFAMILY SSF51679 16 274 1.23E-27 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_02095 6deafdefe8d346163e3fbea9c9300231 277 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 5 275 1.3E-111 T 12-10-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted TL08_02095 6deafdefe8d346163e3fbea9c9300231 277 Gene3D G3DSA:3.20.20.30 120 275 3.8E-12 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_02095 6deafdefe8d346163e3fbea9c9300231 277 Gene3D G3DSA:3.20.20.30 13 119 9.4E-7 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_02095 6deafdefe8d346163e3fbea9c9300231 277 Pfam PF00296 Luciferase-like monooxygenase 18 115 5.1E-5 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_19925 c93e8897d8693816ffe214585bd4e28d 317 SUPERFAMILY SSF161098 77 301 4.32E-57 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19925 c93e8897d8693816ffe214585bd4e28d 317 Gene3D G3DSA:1.10.3720.10 73 312 1.2E-61 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19925 c93e8897d8693816ffe214585bd4e28d 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 308 1.5E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_05555 bc4cf13b2a28abdf51b0dbd6ae7a1d82 309 SUPERFAMILY SSF46785 6 109 5.46E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05555 bc4cf13b2a28abdf51b0dbd6ae7a1d82 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.8E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_05555 bc4cf13b2a28abdf51b0dbd6ae7a1d82 309 Gene3D G3DSA:1.10.10.10 2 90 2.7E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05555 bc4cf13b2a28abdf51b0dbd6ae7a1d82 309 SUPERFAMILY SSF53850 89 293 2.47E-34 T 12-10-2018 TL08_05555 bc4cf13b2a28abdf51b0dbd6ae7a1d82 309 Pfam PF03466 LysR substrate binding domain 88 293 9.9E-39 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_05555 bc4cf13b2a28abdf51b0dbd6ae7a1d82 309 Gene3D G3DSA:3.40.190.290 92 295 2.6E-38 T 12-10-2018 TL08_16260 bab78aa2da02659632e00e4a2e8b3ed0 261 SUPERFAMILY SSF51735 3 253 2.51E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16260 bab78aa2da02659632e00e4a2e8b3ed0 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 252 1.9E-17 T 12-10-2018 TL08_16260 bab78aa2da02659632e00e4a2e8b3ed0 261 Gene3D G3DSA:3.40.50.720 5 258 6.5E-40 T 12-10-2018 TL08_16260 bab78aa2da02659632e00e4a2e8b3ed0 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16260 bab78aa2da02659632e00e4a2e8b3ed0 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 62 73 8.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16260 bab78aa2da02659632e00e4a2e8b3ed0 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16260 bab78aa2da02659632e00e4a2e8b3ed0 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16260 bab78aa2da02659632e00e4a2e8b3ed0 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_04700 9f4b893cd0e15f86012465350b9d87a2 392 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_04700 9f4b893cd0e15f86012465350b9d87a2 392 SUPERFAMILY SSF50331 237 388 8.22E-20 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TL08_04700 9f4b893cd0e15f86012465350b9d87a2 392 SUPERFAMILY SSF52540 4 243 1.73E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04700 9f4b893cd0e15f86012465350b9d87a2 392 Gene3D G3DSA:2.40.50.940 223 381 5.9E-28 T 12-10-2018 TL08_04700 9f4b893cd0e15f86012465350b9d87a2 392 Gene3D G3DSA:2.40.50.140 287 372 5.9E-28 T 12-10-2018 TL08_04700 9f4b893cd0e15f86012465350b9d87a2 392 Pfam PF00005 ABC transporter 21 162 8.6E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_04700 9f4b893cd0e15f86012465350b9d87a2 392 SMART SM00382 29 212 1.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_04700 9f4b893cd0e15f86012465350b9d87a2 392 Gene3D G3DSA:3.40.50.300 4 222 2.8E-65 T 12-10-2018 TL08_24260 22f081af6ab84c7bacbc9d180e1733d9 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 3.1E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_24260 22f081af6ab84c7bacbc9d180e1733d9 211 SUPERFAMILY SSF46689 9 72 8.98E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_24260 22f081af6ab84c7bacbc9d180e1733d9 211 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 150 204 1.8E-18 T 12-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type TL08_24260 22f081af6ab84c7bacbc9d180e1733d9 211 SUPERFAMILY SSF48498 81 203 4.71E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_24260 22f081af6ab84c7bacbc9d180e1733d9 211 Gene3D G3DSA:1.10.10.60 8 64 1.9E-18 T 12-10-2018 TL08_24260 22f081af6ab84c7bacbc9d180e1733d9 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_24260 22f081af6ab84c7bacbc9d180e1733d9 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_24260 22f081af6ab84c7bacbc9d180e1733d9 211 Gene3D G3DSA:1.10.357.10 72 206 2.7E-35 T 12-10-2018 TL08_25275 9f0277735bb65d9b879ba5edad4ba33c 228 SUPERFAMILY SSF53955 41 120 4.93E-32 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_25275 9f0277735bb65d9b879ba5edad4ba33c 228 Gene3D G3DSA:3.10.350.10 182 226 1.3E-13 T 12-10-2018 IPR036779 LysM domain superfamily TL08_25275 9f0277735bb65d9b879ba5edad4ba33c 228 Pfam PF06737 Transglycosylase-like domain 41 114 9.4E-35 T 12-10-2018 IPR010618 Transglycosylase-like TL08_25275 9f0277735bb65d9b879ba5edad4ba33c 228 SMART SM00257 182 228 6.4E-10 T 12-10-2018 IPR018392 LysM domain TL08_25275 9f0277735bb65d9b879ba5edad4ba33c 228 Pfam PF01476 LysM domain 183 227 2.9E-12 T 12-10-2018 IPR018392 LysM domain TL08_25275 9f0277735bb65d9b879ba5edad4ba33c 228 SUPERFAMILY SSF54106 183 227 2.62E-8 T 12-10-2018 TL08_25275 9f0277735bb65d9b879ba5edad4ba33c 228 Gene3D G3DSA:1.10.530.10 12 121 2.6E-37 T 12-10-2018 TL08_07225 e5832f27ce7e24d423e1e0e46a2c46b1 320 Pfam PF11303 Protein of unknown function (DUF3105) 84 210 9.0E-42 T 12-10-2018 IPR021454 Protein of unknown function DUF3105 TL08_04380 c687552236258dfc16a7ae39a11e447a 551 SUPERFAMILY SSF161098 26 256 3.14E-43 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04380 c687552236258dfc16a7ae39a11e447a 551 Gene3D G3DSA:1.10.3720.10 286 544 4.4E-43 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04380 c687552236258dfc16a7ae39a11e447a 551 Gene3D G3DSA:1.10.3720.10 26 268 2.2E-49 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04380 c687552236258dfc16a7ae39a11e447a 551 SUPERFAMILY SSF161098 281 543 1.28E-41 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04380 c687552236258dfc16a7ae39a11e447a 551 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 360 531 2.1E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_04380 c687552236258dfc16a7ae39a11e447a 551 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 262 4.1E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 SUPERFAMILY SSF52540 490 798 4.69E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 3.9E-17 T 12-10-2018 IPR004176 Clp, N-terminal TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 6.5E-18 T 12-10-2018 IPR004176 Clp, N-terminal TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 SUPERFAMILY SSF81923 3 144 2.75E-32 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 796 1.1E-24 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Pfam PF02151 UvrB/uvrC motif 421 453 5.7E-8 T 12-10-2018 IPR001943 UVR domain GO:0005515 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Gene3D G3DSA:1.10.1780.10 1 148 5.4E-64 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Gene3D G3DSA:3.40.50.300 471 717 4.0E-96 T 12-10-2018 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 7.5E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 7.5E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 7.5E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 7.5E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 SMART SM00382 541 720 7.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 SMART SM00382 204 349 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Gene3D G3DSA:3.40.50.300 164 352 4.9E-72 T 12-10-2018 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 SMART SM01086 719 815 4.4E-32 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 SUPERFAMILY SSF52540 167 471 5.62E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Gene3D G3DSA:3.40.50.300 353 469 1.7E-39 T 12-10-2018 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Pfam PF07724 AAA domain (Cdc48 subfamily) 540 713 1.5E-50 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 338 4.5E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_01745 6acf383b10261ec94ce1fa5ac64204ea 852 Gene3D G3DSA:1.10.8.60 719 814 4.4E-26 T 12-10-2018 TL08_07285 7488b1f706a994ae7821fa972f9d39eb 215 Pfam PF01300 Telomere recombination 23 197 3.9E-48 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 TL08_07285 7488b1f706a994ae7821fa972f9d39eb 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 11 205 4.0E-62 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 TL08_07285 7488b1f706a994ae7821fa972f9d39eb 215 Gene3D G3DSA:3.90.870.10 3 213 2.1E-67 T 12-10-2018 TL08_07285 7488b1f706a994ae7821fa972f9d39eb 215 SUPERFAMILY SSF55821 5 206 7.63E-58 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TL08_15775 853fe54474602895affcc960e816704d 782 Pfam PF00550 Phosphopantetheine attachment site 714 777 2.8E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15775 853fe54474602895affcc960e816704d 782 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 236 631 6.8E-106 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_15775 853fe54474602895affcc960e816704d 782 Gene3D G3DSA:3.30.300.30 601 698 2.8E-24 T 12-10-2018 TL08_15775 853fe54474602895affcc960e816704d 782 Gene3D G3DSA:3.40.50.12780 204 600 5.0E-99 T 12-10-2018 TL08_15775 853fe54474602895affcc960e816704d 782 ProSitePatterns PS00455 Putative AMP-binding domain signature. 351 362 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_15775 853fe54474602895affcc960e816704d 782 SMART SM00823 Phosphopantetheine attachment site 712 781 5.2E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15775 853fe54474602895affcc960e816704d 782 Gene3D G3DSA:1.10.1200.10 699 782 5.1E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15775 853fe54474602895affcc960e816704d 782 SUPERFAMILY SSF47336 709 778 1.26E-12 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15775 853fe54474602895affcc960e816704d 782 SUPERFAMILY SSF56801 203 724 1.57E-116 T 12-10-2018 TL08_15775 853fe54474602895affcc960e816704d 782 Pfam PF00501 AMP-binding enzyme 216 607 1.3E-75 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_15775 853fe54474602895affcc960e816704d 782 Pfam PF13193 AMP-binding enzyme C-terminal domain 618 686 2.2E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 96 5.9E-16 T 12-10-2018 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Pfam PF00384 Molybdopterin oxidoreductase 554 681 1.7E-6 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Pfam PF00384 Molybdopterin oxidoreductase 320 463 2.7E-10 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Gene3D G3DSA:3.40.50.740 326 396 1.1E-13 T 12-10-2018 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Gene3D G3DSA:3.40.50.740 514 737 2.8E-27 T 12-10-2018 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 SUPERFAMILY SSF54292 18 93 2.03E-17 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Gene3D G3DSA:2.40.40.20 738 844 2.2E-5 T 12-10-2018 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 120 132 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Gene3D G3DSA:2.20.25.90 264 316 1.9E-9 T 12-10-2018 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 144 5.4E-16 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 SUPERFAMILY SSF53706 254 717 7.54E-71 T 12-10-2018 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Pfam PF01568 Molydopterin dinucleotide binding domain 752 830 6.4E-7 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 SUPERFAMILY SSF50692 746 829 6.12E-10 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 47 64 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Gene3D G3DSA:3.40.228.10 397 458 1.1E-13 T 12-10-2018 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 SMART SM00929 105 145 3.1E-19 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 SMART SM00926 263 317 2.1E-5 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 168 178 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 SUPERFAMILY SSF54862 98 259 2.89E-28 T 12-10-2018 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Gene3D G3DSA:3.10.20.740 18 145 6.8E-32 T 12-10-2018 TL08_02635 4f9a8b893482e7365f2cc4bd3df70a7c 856 Gene3D G3DSA:3.30.70.20 151 210 2.3E-5 T 12-10-2018 TL08_11255 aea95655aa9c727930892081bea471d7 308 Pfam PF00005 ABC transporter 18 150 1.6E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_11255 aea95655aa9c727930892081bea471d7 308 SUPERFAMILY SSF52540 2 206 5.12E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11255 aea95655aa9c727930892081bea471d7 308 Gene3D G3DSA:3.40.50.300 1 211 2.5E-35 T 12-10-2018 TL08_11255 aea95655aa9c727930892081bea471d7 308 SMART SM00382 27 205 1.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 554 959 2.2E-110 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Pfam PF00550 Phosphopantetheine attachment site 1048 1109 3.4E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 SUPERFAMILY SSF47336 1041 1111 1.83E-11 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Gene3D G3DSA:3.30.559.10 76 437 1.9E-124 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Gene3D G3DSA:1.10.1200.10 1033 1117 1.7E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Pfam PF13193 AMP-binding enzyme C-terminal domain 944 1018 2.0E-5 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 SUPERFAMILY SSF52777 78 246 8.15E-45 T 12-10-2018 TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Gene3D G3DSA:3.40.50.12780 517 929 5.4E-111 T 12-10-2018 TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Gene3D G3DSA:1.10.10.1830 3 55 5.7E-12 T 12-10-2018 TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Pfam PF00668 Condensation domain 75 510 4.6E-85 T 12-10-2018 IPR001242 Condensation domain TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1070 1085 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 SUPERFAMILY SSF52777 253 499 4.89E-53 T 12-10-2018 TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Gene3D G3DSA:3.30.559.30 250 496 1.9E-124 T 12-10-2018 TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Gene3D G3DSA:3.30.300.30 930 1032 2.0E-23 T 12-10-2018 TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 Pfam PF00501 AMP-binding enzyme 535 935 4.4E-87 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 ProSitePatterns PS00455 Putative AMP-binding domain signature. 673 684 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_14885 1f89f4a665a4eb6524051b5bc2600419 1149 SUPERFAMILY SSF56801 490 1058 1.05E-132 T 12-10-2018 TL08_11470 90e8e3c611f260a65604d812a1803965 162 Gene3D G3DSA:1.10.10.1930 75 162 7.4E-34 T 12-10-2018 IPR038099 BldD-like, C-terminal domain superfamily TL08_11470 90e8e3c611f260a65604d812a1803965 162 SUPERFAMILY SSF47413 4 71 2.03E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_11470 90e8e3c611f260a65604d812a1803965 162 Pfam PF01381 Helix-turn-helix 12 68 7.4E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_11470 90e8e3c611f260a65604d812a1803965 162 Gene3D G3DSA:1.10.260.40 1 70 1.3E-32 T 12-10-2018 TL08_11470 90e8e3c611f260a65604d812a1803965 162 SMART SM00530 11 68 3.3E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_00330 3bced890b3823cff7b64027a63a8048b 219 Gene3D G3DSA:3.30.1060.10 5 219 1.4E-91 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TL08_00330 3bced890b3823cff7b64027a63a8048b 219 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 47 210 36.326 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TL08_00330 3bced890b3823cff7b64027a63a8048b 219 Pfam PF01625 Peptide methionine sulfoxide reductase 49 204 1.2E-66 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TL08_00330 3bced890b3823cff7b64027a63a8048b 219 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 49 204 4.0E-65 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TL08_00330 3bced890b3823cff7b64027a63a8048b 219 SUPERFAMILY SSF55068 14 214 2.49E-78 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 Gene3D G3DSA:1.10.10.10 276 354 4.5E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 25 254 2.2E-105 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 272 347 1.0E-29 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 SUPERFAMILY SSF46785 275 349 1.74E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 272 345 5.8E-28 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 365 154.053 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 43 345 1.2E-132 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 SMART SM00382 70 203 1.7E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 SUPERFAMILY SSF52540 39 270 2.36E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 Gene3D G3DSA:3.40.50.300 39 200 3.4E-35 T 12-10-2018 TL08_10520 debf7b71d89eb7f4e10ce761bcab7f51 365 Gene3D G3DSA:1.10.8.60 201 275 3.2E-30 T 12-10-2018 TL08_11550 bb02125443cf1740b25ecdc750ba91b6 253 Gene3D G3DSA:3.40.50.150 12 193 1.5E-19 T 12-10-2018 TL08_11550 bb02125443cf1740b25ecdc750ba91b6 253 Gene3D G3DSA:1.10.8.900 137 201 1.5E-19 T 12-10-2018 TL08_11550 bb02125443cf1740b25ecdc750ba91b6 253 SUPERFAMILY SSF53335 21 145 2.71E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_11550 bb02125443cf1740b25ecdc750ba91b6 253 Pfam PF08241 Methyltransferase domain 40 126 2.0E-10 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_15000 559d7a4f1e16c637ae78618fb04423d1 254 Gene3D G3DSA:2.40.10.10 58 139 3.9E-13 T 12-10-2018 TL08_15000 559d7a4f1e16c637ae78618fb04423d1 254 Pfam PF00089 Trypsin 55 248 3.8E-23 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_15000 559d7a4f1e16c637ae78618fb04423d1 254 SMART SM00020 47 248 9.4E-15 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_15000 559d7a4f1e16c637ae78618fb04423d1 254 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 200 212 4.4E-7 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_15000 559d7a4f1e16c637ae78618fb04423d1 254 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 118 132 4.4E-7 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_15000 559d7a4f1e16c637ae78618fb04423d1 254 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 72 87 4.4E-7 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_15000 559d7a4f1e16c637ae78618fb04423d1 254 SUPERFAMILY SSF50494 43 252 3.14E-36 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_12020 5f4bcb5ad3d6d2dca157f4be9c8d8310 277 Gene3D G3DSA:3.40.50.150 71 266 2.8E-58 T 12-10-2018 TL08_12020 5f4bcb5ad3d6d2dca157f4be9c8d8310 277 PIRSF PIRSF017269 2 272 2.7E-84 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TL08_12020 5f4bcb5ad3d6d2dca157f4be9c8d8310 277 Gene3D G3DSA:3.10.330.20 2 69 1.2E-25 T 12-10-2018 TL08_12020 5f4bcb5ad3d6d2dca157f4be9c8d8310 277 SUPERFAMILY SSF53335 7 260 1.18E-71 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_12020 5f4bcb5ad3d6d2dca157f4be9c8d8310 277 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 237 4.0E-19 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TL08_12020 5f4bcb5ad3d6d2dca157f4be9c8d8310 277 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 5 55 1.6E-29 T 12-10-2018 TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 SMART SM00788 3 423 3.1E-274 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 Gene3D G3DSA:3.90.170.10 266 428 1.7E-67 T 12-10-2018 TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 Gene3D G3DSA:1.10.300.10 101 200 8.3E-96 T 12-10-2018 TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 Pfam PF00709 Adenylosuccinate synthetase 4 422 4.6E-174 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 Gene3D G3DSA:3.40.440.10 7 256 8.3E-96 T 12-10-2018 TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 4.7E-163 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 198.855 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 SUPERFAMILY SSF52540 1 426 6.05E-168 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26160 7ce0c9f0f78b97bac6fa33e7f00770e4 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TL08_21825 0efade2bc65ae7045c884064f7dc18e2 192 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 13 191 9.0E-49 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 TL08_21825 0efade2bc65ae7045c884064f7dc18e2 192 SUPERFAMILY SSF52540 13 191 3.48E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21825 0efade2bc65ae7045c884064f7dc18e2 192 PIRSF PIRSF006135 11 192 6.1E-45 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 TL08_21825 0efade2bc65ae7045c884064f7dc18e2 192 Gene3D G3DSA:3.40.50.300 13 192 1.4E-46 T 12-10-2018 TL08_10785 909f247190423ae90825bd5339263200 353 Pfam PF00571 CBS domain 226 271 2.5E-4 T 12-10-2018 IPR000644 CBS domain TL08_10785 909f247190423ae90825bd5339263200 353 Gene3D G3DSA:3.10.580.10 199 344 4.8E-27 T 12-10-2018 TL08_10785 909f247190423ae90825bd5339263200 353 SMART SM00116 288 336 27.0 T 12-10-2018 IPR000644 CBS domain TL08_10785 909f247190423ae90825bd5339263200 353 SMART SM00116 226 274 8.9E-4 T 12-10-2018 IPR000644 CBS domain TL08_10785 909f247190423ae90825bd5339263200 353 SUPERFAMILY SSF54631 210 342 3.28E-21 T 12-10-2018 TL08_10785 909f247190423ae90825bd5339263200 353 Pfam PF01595 Domain of unknown function DUF21 8 202 1.0E-42 T 12-10-2018 IPR002550 CNNM, transmembrane domain TL08_06350 7a2a50548f813400d41d714ea5150f22 379 SUPERFAMILY SSF46565 1 64 3.27E-22 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TL08_06350 7a2a50548f813400d41d714ea5150f22 379 Pfam PF08378 Nuclease-related domain 222 288 1.3E-4 T 12-10-2018 IPR011528 Nuclease-related domain, NERD TL08_06350 7a2a50548f813400d41d714ea5150f22 379 PRINTS PR00625 DnaJ domain signature 23 38 3.9E-7 T 12-10-2018 IPR001623 DnaJ domain TL08_06350 7a2a50548f813400d41d714ea5150f22 379 PRINTS PR00625 DnaJ domain signature 5 23 3.9E-7 T 12-10-2018 IPR001623 DnaJ domain TL08_06350 7a2a50548f813400d41d714ea5150f22 379 Pfam PF00226 DnaJ domain 3 61 1.1E-16 T 12-10-2018 IPR001623 DnaJ domain TL08_06350 7a2a50548f813400d41d714ea5150f22 379 SMART SM00271 2 56 8.8E-19 T 12-10-2018 IPR001623 DnaJ domain TL08_06350 7a2a50548f813400d41d714ea5150f22 379 Gene3D G3DSA:1.10.287.110 1 78 1.5E-20 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TL08_06350 7a2a50548f813400d41d714ea5150f22 379 ProSitePatterns PS00636 Nt-dnaJ domain signature. 41 60 - T 12-10-2018 IPR018253 DnaJ domain, conserved site TL08_09470 630e1bbe4302365d035bd29981d19dd7 356 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 342 3.6E-92 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_09470 630e1bbe4302365d035bd29981d19dd7 356 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 7.2E-6 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_09470 630e1bbe4302365d035bd29981d19dd7 356 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 346 23.174 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_09470 630e1bbe4302365d035bd29981d19dd7 356 ProSitePatterns PS01348 MraY family signature 2. 175 186 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_09470 630e1bbe4302365d035bd29981d19dd7 356 Pfam PF00953 Glycosyl transferase family 4 82 272 9.0E-38 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TL08_09470 630e1bbe4302365d035bd29981d19dd7 356 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 Gene3D G3DSA:1.25.40.10 636 945 4.4E-93 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 Pfam PF00069 Protein kinase domain 353 559 3.5E-30 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 SUPERFAMILY SSF48452 713 821 4.38E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 SMART SM00220 353 608 3.3E-25 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 Gene3D G3DSA:1.25.40.10 627 787 4.4E-93 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 Gene3D G3DSA:1.10.510.10 441 609 1.7E-103 T 12-10-2018 TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 Pfam PF16919 Protein kinase G rubredoxin domain 240 352 4.3E-33 T 12-10-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 SUPERFAMILY SSF56112 338 609 1.04E-47 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 Pfam PF16918 Protein kinase G tetratricopeptide repeat 624 948 7.7E-85 T 12-10-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 TL08_11005 ab62ef42751aae0cdaeccf7592f83055 950 Gene3D G3DSA:3.30.200.20 305 440 1.7E-103 T 12-10-2018 TL08_10125 d606b43b1a39b438842fd555486b1a24 93 Pfam PF12728 Helix-turn-helix domain 14 61 4.6E-11 T 12-10-2018 TL08_10125 d606b43b1a39b438842fd555486b1a24 93 Gene3D G3DSA:1.10.1660.10 9 68 3.2E-6 T 12-10-2018 TL08_10125 d606b43b1a39b438842fd555486b1a24 93 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 13 61 5.2E-9 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TL08_14935 d39a9aec52775a550d62d71edc648855 260 Pfam PF00561 alpha/beta hydrolase fold 20 125 4.4E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14935 d39a9aec52775a550d62d71edc648855 260 Gene3D G3DSA:3.40.50.1820 1 260 3.3E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14935 d39a9aec52775a550d62d71edc648855 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 1.3E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14935 d39a9aec52775a550d62d71edc648855 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.3E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14935 d39a9aec52775a550d62d71edc648855 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 1.3E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14935 d39a9aec52775a550d62d71edc648855 260 SUPERFAMILY SSF53474 1 259 7.1E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_17950 0ea5b3a9e481b8791a928e2f2addcc6e 202 Pfam PF13302 Acetyltransferase (GNAT) domain 28 168 5.9E-20 T 12-10-2018 IPR000182 GNAT domain TL08_17950 0ea5b3a9e481b8791a928e2f2addcc6e 202 Gene3D G3DSA:3.40.630.30 5 186 4.9E-29 T 12-10-2018 TL08_17950 0ea5b3a9e481b8791a928e2f2addcc6e 202 SUPERFAMILY SSF55729 23 176 9.61E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF52151 1546 1833 6.02E-56 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.40.366.10 3068 3367 3.5E-161 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.40.366.10 1546 1847 4.6E-132 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.40.366.10 551 850 6.9E-156 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF08990 Erythronolide synthase docking 2 27 3.9E-7 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3896 3911 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.30.70.3290 469 895 6.9E-156 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF55048 3192 3256 1.24E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.40.47.10 16 452 1.3E-174 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF47336 933 1039 2.75E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.30.70.3290 1460 1890 4.6E-132 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF53901 30 396 1.36E-95 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF00698 Acyl transferase domain 3069 3349 2.0E-59 T 12-10-2018 IPR014043 Acyl transferase TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF00698 Acyl transferase domain 1546 1863 1.2E-73 T 12-10-2018 IPR014043 Acyl transferase TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF00698 Acyl transferase domain 552 864 2.5E-52 T 12-10-2018 IPR014043 Acyl transferase TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF55048 1675 1731 4.05E-7 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 189 205 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:1.10.1200.10 2435 2528 9.0E-29 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 276 1.7E-78 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2547 2797 3.7E-86 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1024 1265 9.2E-85 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM01294 2454 2521 3.3E-5 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM01294 935 1002 3.2E-5 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM01294 3870 3937 2.1E-4 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2480 2495 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2174 2354 4.2E-33 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3584 3764 1.2E-42 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF47336 3864 3957 1.96E-17 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 553 847 1.0E-108 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3070 3364 5.8E-115 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1548 1844 4.4E-88 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2710 2726 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF08659 KR domain 3584 3762 2.6E-50 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF08659 KR domain 2174 2352 1.2E-47 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF55048 674 738 6.67E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.40.47.10 2538 2990 4.6E-182 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.40.47.10 1015 1456 2.0E-178 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF51735 1952 2161 5.9E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF52151 3067 3360 4.71E-74 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2805 2920 1.0E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1273 1388 2.3E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 284 399 7.8E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF53901 2544 2917 5.29E-94 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00823 Phosphopantetheine attachment site 934 1006 1.6E-23 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00823 Phosphopantetheine attachment site 3869 3941 4.0E-22 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00823 Phosphopantetheine attachment site 2453 2525 1.8E-26 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF52151 550 822 2.2E-66 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF47336 2446 2562 6.15E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00825 Beta-ketoacyl synthase 1026 1441 5.0E-194 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00825 Beta-ketoacyl synthase 2549 2973 6.8E-202 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SMART SM00825 Beta-ketoacyl synthase 36 452 2.4E-198 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF53901 1020 1385 3.51E-98 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.30.70.3290 2991 3412 3.5E-161 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.40.50.720 3418 3848 2.5E-99 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 ProSitePatterns PS00012 Phosphopantetheine attachment site. 961 976 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1178 1194 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF51735 3426 3568 1.14E-16 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:3.40.50.720 1905 2424 1.0E-140 T 12-10-2018 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF51735 3582 3803 2.72E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 402 516 6.5E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2923 3034 3.2E-17 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1391 1510 6.5E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:1.10.1200.10 917 1007 3.2E-26 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Gene3D G3DSA:1.10.1200.10 3853 3941 1.1E-23 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 SUPERFAMILY SSF51735 2172 2394 8.47E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF00550 Phosphopantetheine attachment site 3872 3937 6.8E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF00550 Phosphopantetheine attachment site 937 1002 1.5E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14600 bdd7681c7c5aa0577921e091e758fcf5 4029 Pfam PF00550 Phosphopantetheine attachment site 2455 2521 1.4E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_08615 a0b2ca9d34d15b6ffd2234ac0a08f6e5 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.3E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_08615 a0b2ca9d34d15b6ffd2234ac0a08f6e5 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 8.3E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_08615 a0b2ca9d34d15b6ffd2234ac0a08f6e5 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.3E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_08615 a0b2ca9d34d15b6ffd2234ac0a08f6e5 145 SUPERFAMILY SSF46955 1 116 2.23E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_08615 a0b2ca9d34d15b6ffd2234ac0a08f6e5 145 Gene3D G3DSA:1.10.1660.10 1 134 1.3E-27 T 12-10-2018 TL08_08615 a0b2ca9d34d15b6ffd2234ac0a08f6e5 145 SMART SM00422 1 69 1.1E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_08615 a0b2ca9d34d15b6ffd2234ac0a08f6e5 145 Pfam PF13411 MerR HTH family regulatory protein 1 68 1.2E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24760 a34185e45ff63989efc520fd7544436f 173 Gene3D G3DSA:1.10.10.10 5 169 2.2E-40 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_24760 a34185e45ff63989efc520fd7544436f 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 110 3.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_24760 a34185e45ff63989efc520fd7544436f 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 130 3.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_24760 a34185e45ff63989efc520fd7544436f 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 144 164 3.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_24760 a34185e45ff63989efc520fd7544436f 173 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 94 3.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_24760 a34185e45ff63989efc520fd7544436f 173 SMART SM00347 51 154 2.1E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_24760 a34185e45ff63989efc520fd7544436f 173 SUPERFAMILY SSF46785 18 169 6.03E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_24760 a34185e45ff63989efc520fd7544436f 173 Pfam PF12802 MarR family 56 118 1.2E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PRINTS PR00397 Sirohaem Fe-binding site signature 669 687 1.7E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PRINTS PR00397 Sirohaem Fe-binding site signature 626 644 1.7E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PIRSF PIRSF037149 1 825 0.0 T 12-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 SUPERFAMILY SSF55124 492 631 9.32E-24 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 Pfam PF04324 BFD-like [2Fe-2S] binding domain 418 465 2.9E-10 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 SUPERFAMILY SSF51905 2 186 5.86E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 550 611 1.4E-10 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 5.6E-7 T 12-10-2018 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 5.6E-7 T 12-10-2018 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 5.6E-7 T 12-10-2018 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 SUPERFAMILY SSF51905 148 307 6.32E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.6E-17 T 12-10-2018 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 3.6E-17 T 12-10-2018 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.6E-17 T 12-10-2018 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 3.6E-17 T 12-10-2018 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 Gene3D G3DSA:3.30.413.10 621 780 1.1E-34 T 12-10-2018 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 282 4.2E-48 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 Gene3D G3DSA:3.50.50.60 109 245 1.4E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 622 763 5.0E-20 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 SUPERFAMILY SSF56014 623 797 1.14E-49 T 12-10-2018 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 Gene3D G3DSA:3.50.50.60 6 282 1.4E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 5 791 0.0 T 12-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 669 685 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_09265 2c8dd3cbabb0e5f4d65af4c4466942f3 833 Gene3D G3DSA:1.10.10.1100 417 470 2.0E-10 T 12-10-2018 TL08_04160 94c582c351b0093bc6d7f3788dd7463e 283 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 78 93 1.1E-14 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_04160 94c582c351b0093bc6d7f3788dd7463e 283 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 136 150 1.1E-14 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_04160 94c582c351b0093bc6d7f3788dd7463e 283 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 221 233 1.1E-14 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_04160 94c582c351b0093bc6d7f3788dd7463e 283 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 88 93 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 TL08_04160 94c582c351b0093bc6d7f3788dd7463e 283 Gene3D G3DSA:2.40.10.10 44 283 1.6E-39 T 12-10-2018 TL08_04160 94c582c351b0093bc6d7f3788dd7463e 283 SMART SM00020 51 278 1.8E-31 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_04160 94c582c351b0093bc6d7f3788dd7463e 283 SUPERFAMILY SSF50494 44 282 1.87E-46 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_04160 94c582c351b0093bc6d7f3788dd7463e 283 Pfam PF00089 Trypsin 56 247 4.5E-32 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_04160 94c582c351b0093bc6d7f3788dd7463e 283 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 222 233 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site TL08_13425 ef52fcd5642468a473973a9660f289cc 173 Gene3D G3DSA:1.20.120.1630 2 168 7.5E-22 T 12-10-2018 TL08_13425 ef52fcd5642468a473973a9660f289cc 173 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 76 166 7.2E-32 T 12-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 TL08_10760 0aba740c1651c8b577235ac339513948 188 Pfam PF13411 MerR HTH family regulatory protein 30 99 5.3E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_10760 0aba740c1651c8b577235ac339513948 188 SUPERFAMILY SSF46955 33 118 6.59E-15 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_10760 0aba740c1651c8b577235ac339513948 188 Gene3D G3DSA:1.10.1660.10 29 101 1.8E-13 T 12-10-2018 TL08_10760 0aba740c1651c8b577235ac339513948 188 SMART SM00422 30 102 4.0E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_18870 64059cc437c93428a7c2be7cf5894908 233 Gene3D G3DSA:1.10.287.1060 79 167 1.3E-5 T 12-10-2018 TL08_18870 64059cc437c93428a7c2be7cf5894908 233 SUPERFAMILY SSF140453 89 147 4.05E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_09855 1f62819c686474f019671c547ff57b48 185 SUPERFAMILY SSF55729 6 182 2.36E-45 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_09855 1f62819c686474f019671c547ff57b48 185 Gene3D G3DSA:3.40.630.30 1 184 1.4E-60 T 12-10-2018 TL08_09855 1f62819c686474f019671c547ff57b48 185 SMART SM01006 21 69 5.7E-14 T 12-10-2018 IPR019432 Siderophore biosynthesis protein, conserved domain TL08_09855 1f62819c686474f019671c547ff57b48 185 Pfam PF13523 Acetyltransferase (GNAT) domain 28 170 7.1E-47 T 12-10-2018 TL08_16415 543b1274006423f8afb2798225184bfb 277 SUPERFAMILY SSF51430 10 262 1.83E-80 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_16415 543b1274006423f8afb2798225184bfb 277 PRINTS PR00069 Aldo-keto reductase signature 157 186 1.6E-39 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_16415 543b1274006423f8afb2798225184bfb 277 PRINTS PR00069 Aldo-keto reductase signature 35 59 1.6E-39 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_16415 543b1274006423f8afb2798225184bfb 277 PRINTS PR00069 Aldo-keto reductase signature 91 109 1.6E-39 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_16415 543b1274006423f8afb2798225184bfb 277 PRINTS PR00069 Aldo-keto reductase signature 123 140 1.6E-39 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_16415 543b1274006423f8afb2798225184bfb 277 PRINTS PR00069 Aldo-keto reductase signature 195 219 1.6E-39 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_16415 543b1274006423f8afb2798225184bfb 277 Pfam PF00248 Aldo/keto reductase family 16 258 4.7E-41 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_16415 543b1274006423f8afb2798225184bfb 277 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TL08_16415 543b1274006423f8afb2798225184bfb 277 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TL08_16415 543b1274006423f8afb2798225184bfb 277 Gene3D G3DSA:3.20.20.100 6 271 2.2E-91 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_16415 543b1274006423f8afb2798225184bfb 277 PIRSF PIRSF000097 6 273 5.3E-67 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_21640 f8020111b3b6bb095124508a1586b412 1683 SUPERFAMILY SSF140453 83 136 5.1E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Gene3D G3DSA:3.90.930.1 779 886 3.5E-8 T 12-10-2018 TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Pfam PF05593 RHS Repeat 603 639 9.0E-8 T 12-10-2018 IPR031325 RHS repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Pfam PF05593 RHS Repeat 833 869 1.3E-9 T 12-10-2018 IPR031325 RHS repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Pfam PF05593 RHS Repeat 539 574 1.6E-5 T 12-10-2018 IPR031325 RHS repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Pfam PF05593 RHS Repeat 727 764 2.1E-6 T 12-10-2018 IPR031325 RHS repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Pfam PF05593 RHS Repeat 790 827 1.3E-4 T 12-10-2018 IPR031325 RHS repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Pfam PF05593 RHS Repeat 896 928 1.2E-4 T 12-10-2018 IPR031325 RHS repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Pfam PF05593 RHS Repeat 935 970 1.2E-6 T 12-10-2018 IPR031325 RHS repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Gene3D G3DSA:3.90.930.1 634 774 9.0E-13 T 12-10-2018 TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Gene3D G3DSA:1.10.287.1060 78 168 3.0E-5 T 12-10-2018 TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Gene3D G3DSA:2.180.10.10 934 1374 2.1E-37 T 12-10-2018 TL08_21640 f8020111b3b6bb095124508a1586b412 1683 Pfam PF14436 Bacterial EndoU nuclease 1541 1648 5.1E-6 T 12-10-2018 IPR029501 Bacterial EndoU nuclease TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1302 1374 1.1E-23 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1144 1180 0.0021 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1168 1202 4.0E-7 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 832 873 9.3E-9 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 874 914 0.0011 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 728 767 1.2E-7 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 604 643 1.2E-6 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 778 808 2.4E-5 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 669 707 2.2E-5 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 947 973 4.8E-4 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 645 674 8.6E-5 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 624 664 3.8E-8 T 12-10-2018 IPR006530 YD repeat TL08_21640 f8020111b3b6bb095124508a1586b412 1683 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 539 568 2.6E-5 T 12-10-2018 IPR006530 YD repeat TL08_11990 10d7b326e9e150d7180ac45c704d91f0 473 Pfam PF07690 Major Facilitator Superfamily 19 406 2.9E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_11990 10d7b326e9e150d7180ac45c704d91f0 473 Gene3D G3DSA:1.20.1720.10 12 225 7.2E-47 T 12-10-2018 TL08_11990 10d7b326e9e150d7180ac45c704d91f0 473 SUPERFAMILY SSF103473 3 467 2.7E-64 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_11990 10d7b326e9e150d7180ac45c704d91f0 473 Gene3D G3DSA:1.20.1250.20 259 469 2.4E-15 T 12-10-2018 TL08_00640 cdc3e4a808cdf871fb9204dc1342e138 230 SUPERFAMILY SSF48150 48 215 2.92E-5 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TL08_21020 c648b9831f42b8b81fe23662eb5788dd 305 SUPERFAMILY SSF51735 29 267 4.31E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_21020 c648b9831f42b8b81fe23662eb5788dd 305 Gene3D G3DSA:3.90.25.10 151 287 7.0E-62 T 12-10-2018 TL08_21020 c648b9831f42b8b81fe23662eb5788dd 305 Gene3D G3DSA:3.40.50.720 29 285 7.0E-62 T 12-10-2018 TL08_21020 c648b9831f42b8b81fe23662eb5788dd 305 Pfam PF13460 NAD(P)H-binding 32 201 1.3E-11 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_14930 c57c0886caa65729bd3c6ed68a324b78 207 SUPERFAMILY SSF48498 102 156 1.57E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_14930 c57c0886caa65729bd3c6ed68a324b78 207 Gene3D G3DSA:1.10.357.10 1 202 8.0E-62 T 12-10-2018 TL08_14930 c57c0886caa65729bd3c6ed68a324b78 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 2.0E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14930 c57c0886caa65729bd3c6ed68a324b78 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 2.0E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14930 c57c0886caa65729bd3c6ed68a324b78 207 SUPERFAMILY SSF46689 2 69 7.18E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14930 c57c0886caa65729bd3c6ed68a324b78 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 51 3.5E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_04810 27221f88158e25da91cc3b82e38e1f90 278 SUPERFAMILY SSF69618 9 271 9.02E-51 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_04810 27221f88158e25da91cc3b82e38e1f90 278 Gene3D G3DSA:3.40.50.10090 40 177 2.3E-61 T 12-10-2018 TL08_04810 27221f88158e25da91cc3b82e38e1f90 278 Pfam PF02602 Uroporphyrinogen-III synthase HemD 22 262 1.9E-37 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_04810 27221f88158e25da91cc3b82e38e1f90 278 Gene3D G3DSA:3.40.50.10090 14 261 2.3E-61 T 12-10-2018 TL08_19840 7881511d97e8b309eae69eee86c7798b 278 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 2 258 32.663 T 12-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 TL08_19840 7881511d97e8b309eae69eee86c7798b 278 Pfam PF00149 Calcineurin-like phosphoesterase 5 202 1.5E-15 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_19840 7881511d97e8b309eae69eee86c7798b 278 Gene3D G3DSA:3.60.21.10 1 275 1.1E-61 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_19840 7881511d97e8b309eae69eee86c7798b 278 SUPERFAMILY SSF56300 3 255 1.07E-43 T 12-10-2018 TL08_26235 813c9e1e34024c30d1c20ae9e5918744 467 SUPERFAMILY SSF55103 226 465 6.05E-53 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TL08_26235 813c9e1e34024c30d1c20ae9e5918744 467 Pfam PF02913 FAD linked oxidases, C-terminal domain 222 462 3.9E-56 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TL08_26235 813c9e1e34024c30d1c20ae9e5918744 467 Gene3D G3DSA:3.30.465.40 8 240 3.3E-74 T 12-10-2018 TL08_26235 813c9e1e34024c30d1c20ae9e5918744 467 Gene3D G3DSA:3.30.70.2740 341 423 1.6E-10 T 12-10-2018 TL08_26235 813c9e1e34024c30d1c20ae9e5918744 467 Pfam PF01565 FAD binding domain 46 185 5.3E-43 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TL08_26235 813c9e1e34024c30d1c20ae9e5918744 467 Gene3D G3DSA:1.10.45.10 424 463 4.7E-9 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TL08_26235 813c9e1e34024c30d1c20ae9e5918744 467 SUPERFAMILY SSF56176 9 222 6.07E-77 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_18570 98250a1fea82f16f0d64e9592971bbd0 493 Pfam PF00561 alpha/beta hydrolase fold 87 269 7.8E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_18570 98250a1fea82f16f0d64e9592971bbd0 493 Pfam PF08386 TAP-like protein 389 490 1.8E-22 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal TL08_18570 98250a1fea82f16f0d64e9592971bbd0 493 SUPERFAMILY SSF53474 77 464 2.68E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_01715 92a44316275c9215fbf54abd75d996b5 327 Hamap MF_00158 Pantothenate synthetase [panC]. 23 298 37.598 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TL08_01715 92a44316275c9215fbf54abd75d996b5 327 Gene3D G3DSA:3.30.1300.10 197 311 2.4E-33 T 12-10-2018 TL08_01715 92a44316275c9215fbf54abd75d996b5 327 SUPERFAMILY SSF52374 22 300 6.52E-99 T 12-10-2018 TL08_01715 92a44316275c9215fbf54abd75d996b5 327 Pfam PF02569 Pantoate-beta-alanine ligase 26 296 2.3E-93 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TL08_01715 92a44316275c9215fbf54abd75d996b5 327 Gene3D G3DSA:3.40.50.620 13 196 4.9E-75 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_01715 92a44316275c9215fbf54abd75d996b5 327 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 29 298 2.4E-85 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TL08_00195 7b91915e712fed844d5da43537799b2c 208 Gene3D G3DSA:1.10.357.10 19 206 8.3E-57 T 12-10-2018 TL08_00195 7b91915e712fed844d5da43537799b2c 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_00195 7b91915e712fed844d5da43537799b2c 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_00195 7b91915e712fed844d5da43537799b2c 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_00195 7b91915e712fed844d5da43537799b2c 208 SUPERFAMILY SSF46689 14 85 8.98E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_00195 7b91915e712fed844d5da43537799b2c 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 1.7E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 SUPERFAMILY SSF52172 2 133 2.13E-35 T 12-10-2018 IPR011006 CheY-like superfamily TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 Gene3D G3DSA:3.40.50.12740 2 229 4.7E-65 T 12-10-2018 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 SUPERFAMILY SSF46894 156 227 3.74E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 SMART SM00448 2 115 2.7E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 Pfam PF00072 Response regulator receiver domain 4 116 3.3E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 201 2.6E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 213 2.6E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 185 2.6E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 185 212 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 170 224 1.7E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15205 6d2f8ceabccb63180796f1570c67d2f7 230 SMART SM00421 168 225 7.5E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_11655 e78643609e6883b5f2562c57316ac53d 229 Gene3D G3DSA:3.40.50.360 1 211 4.3E-28 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_11655 e78643609e6883b5f2562c57316ac53d 229 SUPERFAMILY SSF52218 1 177 4.19E-23 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_11655 e78643609e6883b5f2562c57316ac53d 229 Pfam PF02525 Flavodoxin-like fold 1 177 6.6E-21 T 12-10-2018 IPR003680 Flavodoxin-like fold TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 SUPERFAMILY SSF52518 7 188 2.06E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 205 338 3.9E-32 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 440 459 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 SUPERFAMILY SSF52518 375 560 4.88E-47 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 Gene3D G3DSA:3.40.50.970 2 182 2.2E-56 T 12-10-2018 TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 Gene3D G3DSA:3.40.50.1220 195 373 1.2E-44 T 12-10-2018 TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 Gene3D G3DSA:3.40.50.970 374 563 9.4E-48 T 12-10-2018 TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 404 550 1.7E-30 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 12 178 1.2E-48 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TL08_12910 e555ec6e283ffaeb1c6859ee43fc00c6 572 SUPERFAMILY SSF52467 163 371 7.7E-40 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TL08_16515 3f4237b701d98bb8c4d62143f5ca7db0 267 Gene3D G3DSA:3.40.630.30 23 259 3.5E-23 T 12-10-2018 TL08_16515 3f4237b701d98bb8c4d62143f5ca7db0 267 Pfam PF13673 Acetyltransferase (GNAT) domain 177 258 2.6E-6 T 12-10-2018 IPR000182 GNAT domain TL08_16515 3f4237b701d98bb8c4d62143f5ca7db0 267 SUPERFAMILY SSF55729 136 264 3.49E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_04135 8652963babeb858f6dc43e5f65eb4589 506 Pfam PF00155 Aminotransferase class I and II 143 462 1.5E-18 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_04135 8652963babeb858f6dc43e5f65eb4589 506 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 87 3.0E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_04135 8652963babeb858f6dc43e5f65eb4589 506 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 1.5E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_04135 8652963babeb858f6dc43e5f65eb4589 506 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 1.5E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_04135 8652963babeb858f6dc43e5f65eb4589 506 Gene3D G3DSA:3.40.640.10 99 461 6.9E-101 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_04135 8652963babeb858f6dc43e5f65eb4589 506 SUPERFAMILY SSF46785 23 91 1.36E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_04135 8652963babeb858f6dc43e5f65eb4589 506 SUPERFAMILY SSF53383 106 467 1.88E-78 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_04135 8652963babeb858f6dc43e5f65eb4589 506 Gene3D G3DSA:1.10.10.10 21 92 9.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04135 8652963babeb858f6dc43e5f65eb4589 506 SMART SM00345 28 87 9.3E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_04850 b2ee4d524f7f92c6965520b3e676e462 396 PRINTS PR01217 Proline rich extensin signature 7 23 2.8E-9 T 12-10-2018 TL08_04850 b2ee4d524f7f92c6965520b3e676e462 396 PRINTS PR01217 Proline rich extensin signature 56 77 2.8E-9 T 12-10-2018 TL08_04850 b2ee4d524f7f92c6965520b3e676e462 396 PRINTS PR01217 Proline rich extensin signature 37 49 2.8E-9 T 12-10-2018 TL08_04850 b2ee4d524f7f92c6965520b3e676e462 396 PRINTS PR01217 Proline rich extensin signature 151 163 2.8E-9 T 12-10-2018 TL08_04850 b2ee4d524f7f92c6965520b3e676e462 396 PRINTS PR01217 Proline rich extensin signature 118 143 2.8E-9 T 12-10-2018 TL08_04850 b2ee4d524f7f92c6965520b3e676e462 396 Pfam PF04228 Putative neutral zinc metallopeptidase 208 387 4.6E-19 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative TL08_04395 f41c65b474e9e7bbc9c19896a28ac6dc 337 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_04395 f41c65b474e9e7bbc9c19896a28ac6dc 337 Pfam PF00005 ABC transporter 48 192 3.2E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_04395 f41c65b474e9e7bbc9c19896a28ac6dc 337 SMART SM00382 56 240 4.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_04395 f41c65b474e9e7bbc9c19896a28ac6dc 337 Gene3D G3DSA:3.40.50.300 21 264 1.4E-57 T 12-10-2018 TL08_04395 f41c65b474e9e7bbc9c19896a28ac6dc 337 SUPERFAMILY SSF52540 29 255 6.88E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08725 134bc7126e9ff5dcb005ce796ba25896 717 Pfam PF03235 Protein of unknown function DUF262 14 232 4.6E-27 T 12-10-2018 IPR004919 Domain of unknown function DUF262 TL08_25665 2842cd68b7a8e6fb00e112e3322792e4 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 7 173 2.4E-51 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TL08_25665 2842cd68b7a8e6fb00e112e3322792e4 181 SUPERFAMILY SSF51182 3 177 2.02E-52 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_25665 2842cd68b7a8e6fb00e112e3322792e4 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 8 170 2.0E-46 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TL08_25665 2842cd68b7a8e6fb00e112e3322792e4 181 Gene3D G3DSA:2.60.120.10 2 181 6.5E-51 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_14080 92476d28350d6556b7a32061f5bfb05d 292 Gene3D G3DSA:3.90.25.10 140 270 3.3E-83 T 12-10-2018 TL08_14080 92476d28350d6556b7a32061f5bfb05d 292 Gene3D G3DSA:3.40.50.720 5 269 3.3E-83 T 12-10-2018 TL08_14080 92476d28350d6556b7a32061f5bfb05d 292 SUPERFAMILY SSF51735 4 247 6.76E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14080 92476d28350d6556b7a32061f5bfb05d 292 Pfam PF13460 NAD(P)H-binding 8 188 1.3E-21 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_03220 91516fe06561892ecb013eececbf4b85 473 SUPERFAMILY SSF55874 311 469 1.03E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_03220 91516fe06561892ecb013eececbf4b85 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 320 1.1E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_03220 91516fe06561892ecb013eececbf4b85 473 Gene3D G3DSA:1.10.287.130 200 321 4.7E-26 T 12-10-2018 TL08_03220 91516fe06561892ecb013eececbf4b85 473 Pfam PF00672 HAMP domain 196 241 8.8E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_03220 91516fe06561892ecb013eececbf4b85 473 SMART SM00387 361 472 8.6E-34 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_03220 91516fe06561892ecb013eececbf4b85 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 2.2E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03220 91516fe06561892ecb013eececbf4b85 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 2.2E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03220 91516fe06561892ecb013eececbf4b85 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 2.2E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03220 91516fe06561892ecb013eececbf4b85 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 2.2E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_03220 91516fe06561892ecb013eececbf4b85 473 SUPERFAMILY SSF47384 232 322 1.29E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_03220 91516fe06561892ecb013eececbf4b85 473 SMART SM00304 196 248 2.7E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_03220 91516fe06561892ecb013eececbf4b85 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 469 3.7E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_03220 91516fe06561892ecb013eececbf4b85 473 SUPERFAMILY SSF158472 196 244 1.83E-5 T 12-10-2018 TL08_03220 91516fe06561892ecb013eececbf4b85 473 SMART SM00388 249 321 9.8E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_03220 91516fe06561892ecb013eececbf4b85 473 Gene3D G3DSA:3.30.565.10 323 472 1.0E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 SUPERFAMILY SSF51971 4 316 5.47E-60 T 12-10-2018 TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 SUPERFAMILY SSF51971 254 442 7.3E-10 T 12-10-2018 TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 174 3.8E-12 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 Gene3D G3DSA:3.40.50.720 7 442 5.6E-150 T 12-10-2018 TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 9.8E-21 T 12-10-2018 TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 PRINTS PR00419 Adrenodoxin reductase family signature 74 84 9.8E-21 T 12-10-2018 TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 PRINTS PR00419 Adrenodoxin reductase family signature 31 44 9.8E-21 T 12-10-2018 TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 PRINTS PR00419 Adrenodoxin reductase family signature 145 159 9.8E-21 T 12-10-2018 TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 PIRSF PIRSF000362 1 448 5.8E-165 T 12-10-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TL08_09635 d1af75634a4fc1e2ff37aadfedeef7f3 448 Gene3D G3DSA:3.50.50.60 48 321 5.6E-150 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_10875 4c3645ca7dd58389efbe0d28bd1d0411 360 Gene3D G3DSA:1.10.8.300 215 332 4.4E-36 T 12-10-2018 TL08_10875 4c3645ca7dd58389efbe0d28bd1d0411 360 PIRSF PIRSF002849 3 337 1.4E-132 T 12-10-2018 TL08_10875 4c3645ca7dd58389efbe0d28bd1d0411 360 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 56 186 3.7E-58 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TL08_10875 4c3645ca7dd58389efbe0d28bd1d0411 360 SUPERFAMILY SSF52540 24 307 1.24E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10875 4c3645ca7dd58389efbe0d28bd1d0411 360 Gene3D G3DSA:3.40.50.300 37 203 6.7E-43 T 12-10-2018 TL08_05910 42df03fb1b71e90b52cb5bf8e369f7b5 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 131 2.5E-22 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_05910 42df03fb1b71e90b52cb5bf8e369f7b5 332 SUPERFAMILY SSF51735 141 296 1.82E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05910 42df03fb1b71e90b52cb5bf8e369f7b5 332 SUPERFAMILY SSF50129 7 173 9.59E-41 T 12-10-2018 IPR011032 GroES-like superfamily TL08_05910 42df03fb1b71e90b52cb5bf8e369f7b5 332 Gene3D G3DSA:3.90.180.10 13 316 3.7E-74 T 12-10-2018 TL08_05910 42df03fb1b71e90b52cb5bf8e369f7b5 332 Gene3D G3DSA:3.40.50.720 151 278 3.7E-74 T 12-10-2018 TL08_05910 42df03fb1b71e90b52cb5bf8e369f7b5 332 Pfam PF00107 Zinc-binding dehydrogenase 175 291 3.2E-13 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_08350 ae41a01e57016c66fa43b2fd06b4d8f0 268 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 59 212 5.2E-27 T 12-10-2018 IPR006342 Methyltransferase FkbM TL08_08350 ae41a01e57016c66fa43b2fd06b4d8f0 268 Gene3D G3DSA:3.40.50.150 39 239 1.3E-33 T 12-10-2018 TL08_08350 ae41a01e57016c66fa43b2fd06b4d8f0 268 Pfam PF05050 Methyltransferase FkbM domain 62 236 2.3E-18 T 12-10-2018 IPR006342 Methyltransferase FkbM TL08_08350 ae41a01e57016c66fa43b2fd06b4d8f0 268 SUPERFAMILY SSF53335 34 244 9.83E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_08940 4854cbdb58d00791c26f282a28761f10 418 Gene3D G3DSA:3.40.50.720 8 171 2.5E-43 T 12-10-2018 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 SUPERFAMILY SSF55347 149 285 4.58E-53 T 12-10-2018 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 Gene3D G3DSA:1.10.1740.10 323 408 6.1E-28 T 12-10-2018 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 Pfam PF13288 DXP reductoisomerase C-terminal domain 283 400 5.7E-32 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 16 155 4.6E-35 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 PIRSF PIRSF006205 13 410 3.5E-132 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 15 404 1.3E-112 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 16 405 43.123 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 SUPERFAMILY SSF69055 314 406 8.76E-25 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 167 250 1.6E-35 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TL08_08940 4854cbdb58d00791c26f282a28761f10 418 SUPERFAMILY SSF51735 14 171 1.13E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16090 9d1748663ee571d3ded14a9d5149ef44 215 Gene3D G3DSA:3.40.50.150 7 145 1.2E-28 T 12-10-2018 TL08_16090 9d1748663ee571d3ded14a9d5149ef44 215 SUPERFAMILY SSF53335 21 186 3.07E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_16090 9d1748663ee571d3ded14a9d5149ef44 215 Pfam PF13649 Methyltransferase domain 39 129 3.3E-16 T 12-10-2018 TL08_12505 84417f778be5ef3e2a90e9693da65d33 445 Gene3D G3DSA:1.10.10.10 2 68 9.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12505 84417f778be5ef3e2a90e9693da65d33 445 SUPERFAMILY SSF53383 82 436 2.2E-64 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_12505 84417f778be5ef3e2a90e9693da65d33 445 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.9E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_12505 84417f778be5ef3e2a90e9693da65d33 445 SMART SM00345 7 66 4.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_12505 84417f778be5ef3e2a90e9693da65d33 445 Pfam PF00155 Aminotransferase class I and II 125 429 1.6E-19 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_12505 84417f778be5ef3e2a90e9693da65d33 445 Gene3D G3DSA:3.90.1150.10 118 434 3.1E-59 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_12505 84417f778be5ef3e2a90e9693da65d33 445 Gene3D G3DSA:3.40.640.10 119 333 3.1E-59 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_12505 84417f778be5ef3e2a90e9693da65d33 445 SUPERFAMILY SSF46785 4 70 4.08E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23435 7e834704cd427de0782eb178f2bb2d21 333 SUPERFAMILY SSF51735 1 323 2.9E-96 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_23435 7e834704cd427de0782eb178f2bb2d21 333 Gene3D G3DSA:3.40.50.720 2 306 3.5E-120 T 12-10-2018 TL08_23435 7e834704cd427de0782eb178f2bb2d21 333 Gene3D G3DSA:3.90.25.10 193 314 3.5E-120 T 12-10-2018 TL08_23435 7e834704cd427de0782eb178f2bb2d21 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 321 3.7E-133 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 TL08_23435 7e834704cd427de0782eb178f2bb2d21 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 307 3.9E-77 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_01180 f84d9827f6da1765545585ce7f695054 332 PRINTS PR00839 V8 serine protease family signature 231 244 8.7E-24 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TL08_01180 f84d9827f6da1765545585ce7f695054 332 PRINTS PR00839 V8 serine protease family signature 281 293 8.7E-24 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TL08_01180 f84d9827f6da1765545585ce7f695054 332 PRINTS PR00839 V8 serine protease family signature 111 128 8.7E-24 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TL08_01180 f84d9827f6da1765545585ce7f695054 332 PRINTS PR00839 V8 serine protease family signature 264 280 8.7E-24 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TL08_01180 f84d9827f6da1765545585ce7f695054 332 PRINTS PR00839 V8 serine protease family signature 136 153 8.7E-24 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 TL08_01180 f84d9827f6da1765545585ce7f695054 332 Gene3D G3DSA:2.40.10.10 108 293 1.6E-57 T 12-10-2018 TL08_01180 f84d9827f6da1765545585ce7f695054 332 Pfam PF13365 Trypsin-like peptidase domain 136 289 8.2E-9 T 12-10-2018 TL08_01180 f84d9827f6da1765545585ce7f695054 332 ProSitePatterns PS00673 Serine proteases, V8 family, serine active site. 270 280 - T 12-10-2018 IPR000126 Serine proteases, V8 family, serine active site GO:0006508|GO:0008236 TL08_01180 f84d9827f6da1765545585ce7f695054 332 Gene3D G3DSA:2.40.10.10 121 221 1.6E-57 T 12-10-2018 TL08_01180 f84d9827f6da1765545585ce7f695054 332 SUPERFAMILY SSF50494 101 316 4.76E-28 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_08560 44fde67c078c09d425ea6dd497367104 291 Gene3D G3DSA:3.10.310.10 6 141 8.9E-85 T 12-10-2018 TL08_08560 44fde67c078c09d425ea6dd497367104 291 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 282 28.236 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TL08_08560 44fde67c078c09d425ea6dd497367104 291 Pfam PF01678 Diaminopimelate epimerase 151 274 1.0E-21 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TL08_08560 44fde67c078c09d425ea6dd497367104 291 Pfam PF01678 Diaminopimelate epimerase 6 133 6.7E-34 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TL08_08560 44fde67c078c09d425ea6dd497367104 291 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 280 3.1E-64 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TL08_08560 44fde67c078c09d425ea6dd497367104 291 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 75 89 - T 12-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 TL08_08560 44fde67c078c09d425ea6dd497367104 291 SUPERFAMILY SSF54506 141 280 3.14E-27 T 12-10-2018 TL08_08560 44fde67c078c09d425ea6dd497367104 291 SUPERFAMILY SSF54506 4 135 1.24E-35 T 12-10-2018 TL08_08560 44fde67c078c09d425ea6dd497367104 291 Gene3D G3DSA:3.10.310.10 142 278 8.9E-85 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF51735 1362 1572 6.26E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.10.129.110 906 1184 1.6E-110 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.10.129.110 2582 2843 2.2E-84 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF47336 3275 3356 8.38E-19 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF55048 680 742 1.44E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF47336 1636 1747 4.19E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00826 2593 2735 2.5E-56 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00826 917 1075 6.7E-82 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF08990 Erythronolide synthase docking 4 27 3.5E-7 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00823 Phosphopantetheine attachment site 1641 1713 1.3E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00823 Phosphopantetheine attachment site 3280 3352 1.4E-26 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.40.366.10 2261 2530 8.8E-144 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.40.366.10 558 854 5.1E-155 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF53901 31 405 7.6E-107 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM01294 1642 1709 6.2E-4 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 560 851 1.5E-115 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2263 2527 1.5E-105 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.40.50.720 1186 1615 8.6E-118 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.40.50.720 2849 3251 1.5E-95 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1895 1911 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.40.47.10 24 477 3.8E-188 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.40.47.10 1723 2175 1.7E-188 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 526 1.2E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2108 2227 2.8E-17 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.30.70.3290 2176 2574 8.8E-144 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3025 3201 1.8E-32 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1363 1539 7.9E-57 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF55048 2373 2425 4.32E-8 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF14765 Polyketide synthase dehydratase 2593 2839 1.7E-42 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF14765 Polyketide synthase dehydratase 917 1179 4.8E-56 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF51735 3024 3225 2.97E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF52151 557 842 8.89E-66 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 1.6E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1990 2105 1.5E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 6.2E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1732 1982 4.2E-89 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3307 3322 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF51735 2845 3012 5.51E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF00698 Acyl transferase domain 2262 2545 2.8E-47 T 12-10-2018 IPR014043 Acyl transferase TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF00698 Acyl transferase domain 558 869 1.2E-86 T 12-10-2018 IPR014043 Acyl transferase TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF51735 1184 1350 4.72E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00825 Beta-ketoacyl synthase 1734 2158 2.9E-224 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SMART SM00825 Beta-ketoacyl synthase 36 460 1.2E-218 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:3.30.70.3290 478 898 5.1E-155 T 12-10-2018 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF00550 Phosphopantetheine attachment site 3283 3348 1.6E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF00550 Phosphopantetheine attachment site 1643 1709 1.4E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF53901 1728 2103 4.16E-105 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:1.10.1200.10 3263 3355 7.3E-29 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Gene3D G3DSA:1.10.1200.10 1623 1715 4.3E-31 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 SUPERFAMILY SSF52151 2259 2515 9.16E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1668 1683 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF08659 KR domain 1363 1538 2.5E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16000 19acfffcac89237ad6bdc20c3952ad7c 3428 Pfam PF08659 KR domain 3025 3199 1.2E-45 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_10450 005d4c061243e59aa52641a3db0c2bbe 129 Pfam PF04486 SchA/CurD like domain 1 119 1.8E-45 T 12-10-2018 IPR007575 SchA/CurD-like domain TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 188 200 1.6E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 355 363 1.6E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 266 285 1.6E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 291 300 1.6E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 Gene3D G3DSA:3.40.50.80 256 389 9.4E-28 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 Pfam PF00042 Globin 26 118 3.4E-10 T 12-10-2018 IPR000971 Globin GO:0020037 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 Gene3D G3DSA:2.40.30.10 157 253 5.4E-20 T 12-10-2018 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 SUPERFAMILY SSF63380 160 255 3.05E-22 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 Pfam PF00175 Oxidoreductase NAD-binding domain 267 368 5.0E-15 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 SUPERFAMILY SSF46458 24 151 1.87E-31 T 12-10-2018 IPR009050 Globin-like superfamily TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 Gene3D G3DSA:1.10.490.10 22 156 1.4E-34 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 266 285 4.3E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 355 363 4.3E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 188 198 4.3E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 Pfam PF00970 Oxidoreductase FAD-binding domain 163 255 9.2E-14 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TL08_26300 6953bc39c1de1ffa4411d71cb5811a64 390 SUPERFAMILY SSF52343 259 388 1.07E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TL08_02640 f2376230e4abd9bf9510c78564319b7b 460 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 12 348 24.94 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02640 f2376230e4abd9bf9510c78564319b7b 460 Pfam PF00146 NADH dehydrogenase 19 341 1.8E-124 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02640 f2376230e4abd9bf9510c78564319b7b 460 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 58 73 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02640 f2376230e4abd9bf9510c78564319b7b 460 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 223 236 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_05425 7fc893b95e6734828b15fdcbd3466b69 298 Gene3D G3DSA:1.10.260.40 27 101 6.0E-6 T 12-10-2018 TL08_05425 7fc893b95e6734828b15fdcbd3466b69 298 Pfam PF13560 Helix-turn-helix domain 14 86 9.9E-11 T 12-10-2018 TL08_05425 7fc893b95e6734828b15fdcbd3466b69 298 SUPERFAMILY SSF47413 28 76 6.68E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_05425 7fc893b95e6734828b15fdcbd3466b69 298 Gene3D G3DSA:3.30.450.180 112 289 5.1E-13 T 12-10-2018 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 Pfam PF00005 ABC transporter 945 1079 1.4E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 Gene3D G3DSA:3.40.50.300 364 579 6.7E-42 T 12-10-2018 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 SUPERFAMILY SSF52540 364 569 6.71E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 Pfam PF00664 ABC transporter transmembrane region 12 286 9.0E-16 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 SUPERFAMILY SSF90123 603 896 4.19E-29 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 Pfam PF00005 ABC transporter 389 537 2.0E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 ProSitePatterns PS00211 ABC transporters family signature. 1049 1063 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 SUPERFAMILY SSF90123 8 322 4.58E-34 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 SMART SM00382 402 597 1.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 SMART SM00382 954 1132 4.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 Gene3D G3DSA:3.40.50.300 910 1140 2.7E-56 T 12-10-2018 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 601 1108 1.3E-131 T 12-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 9 576 1.4E-135 T 12-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 Gene3D G3DSA:1.20.1560.10 583 899 8.2E-18 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 Gene3D G3DSA:1.20.1560.10 2 327 1.3E-30 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_00570 01c9179c63ec14bd3a0a838bc7099e09 1163 SUPERFAMILY SSF52540 927 1130 2.76E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20775 9e8c09ca7891ced7d0c536415d6cdd46 682 SUPERFAMILY SSF51445 17 371 1.12E-112 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_20775 9e8c09ca7891ced7d0c536415d6cdd46 682 Pfam PF08533 Beta-galactosidase C-terminal domain 616 677 3.0E-5 T 12-10-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_20775 9e8c09ca7891ced7d0c536415d6cdd46 682 PIRSF PIRSF001084 9 680 9.0E-253 T 12-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_20775 9e8c09ca7891ced7d0c536415d6cdd46 682 Pfam PF08532 Beta-galactosidase trimerisation domain 400 607 9.4E-58 T 12-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_20775 9e8c09ca7891ced7d0c536415d6cdd46 682 Gene3D G3DSA:3.40.50.880 397 611 1.9E-63 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_20775 9e8c09ca7891ced7d0c536415d6cdd46 682 Pfam PF02449 Beta-galactosidase 20 389 1.3E-148 T 12-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_20775 9e8c09ca7891ced7d0c536415d6cdd46 682 Gene3D G3DSA:3.20.20.80 11 392 2.6E-137 T 12-10-2018 TL08_20775 9e8c09ca7891ced7d0c536415d6cdd46 682 SUPERFAMILY SSF52317 397 607 9.77E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_20775 9e8c09ca7891ced7d0c536415d6cdd46 682 Gene3D G3DSA:2.60.40.1180 614 679 6.0E-12 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_02085 b96e8e5e9a15759c433c737ce51f6d41 397 Gene3D G3DSA:3.50.50.60 11 362 9.1E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_02085 b96e8e5e9a15759c433c737ce51f6d41 397 SUPERFAMILY SSF51905 10 380 5.31E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_02085 b96e8e5e9a15759c433c737ce51f6d41 397 Gene3D G3DSA:3.30.9.10 96 323 9.1E-84 T 12-10-2018 TL08_02085 b96e8e5e9a15759c433c737ce51f6d41 397 Pfam PF01266 FAD dependent oxidoreductase 10 358 9.6E-65 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_02085 b96e8e5e9a15759c433c737ce51f6d41 397 SUPERFAMILY SSF54373 230 323 3.53E-18 T 12-10-2018 TL08_02085 b96e8e5e9a15759c433c737ce51f6d41 397 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 11 364 5.5E-104 T 12-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 TL08_05270 1ef5526ca17d581666573a027104ebdf 347 Pfam PF01595 Domain of unknown function DUF21 9 199 1.7E-33 T 12-10-2018 IPR002550 CNNM, transmembrane domain TL08_05270 1ef5526ca17d581666573a027104ebdf 347 SMART SM00116 284 331 0.0019 T 12-10-2018 IPR000644 CBS domain TL08_05270 1ef5526ca17d581666573a027104ebdf 347 Pfam PF00571 CBS domain 282 331 8.4E-6 T 12-10-2018 IPR000644 CBS domain TL08_05270 1ef5526ca17d581666573a027104ebdf 347 Gene3D G3DSA:3.10.580.10 202 333 6.8E-15 T 12-10-2018 TL08_05270 1ef5526ca17d581666573a027104ebdf 347 SUPERFAMILY SSF54631 207 331 1.26E-16 T 12-10-2018 TL08_27050 787dad3648e239e0d742de3de5b3dd91 509 Gene3D G3DSA:1.10.3090.10 189 485 1.6E-45 T 12-10-2018 TL08_27050 787dad3648e239e0d742de3de5b3dd91 509 SUPERFAMILY SSF81891 185 497 2.35E-62 T 12-10-2018 TL08_27050 787dad3648e239e0d742de3de5b3dd91 509 Pfam PF01743 Poly A polymerase head domain 51 182 5.1E-28 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TL08_27050 787dad3648e239e0d742de3de5b3dd91 509 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 213 273 1.3E-15 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TL08_27050 787dad3648e239e0d742de3de5b3dd91 509 Pfam PF01966 HD domain 288 386 4.3E-14 T 12-10-2018 IPR006674 HD domain TL08_27050 787dad3648e239e0d742de3de5b3dd91 509 SUPERFAMILY SSF81301 34 180 7.96E-33 T 12-10-2018 TL08_27050 787dad3648e239e0d742de3de5b3dd91 509 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 26 497 8.2E-232 T 12-10-2018 IPR014065 tRNA adenylyltransferase TL08_27050 787dad3648e239e0d742de3de5b3dd91 509 TIGRFAM TIGR00277 HDIG: HDIG domain 285 367 8.0E-17 T 12-10-2018 IPR006675 HDIG domain TL08_27050 787dad3648e239e0d742de3de5b3dd91 509 Gene3D G3DSA:3.30.460.10 22 180 6.6E-33 T 12-10-2018 TL08_12070 d26e2e4e746217a64c3532217308afcd 263 SUPERFAMILY SSF56235 10 230 2.15E-40 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_12070 d26e2e4e746217a64c3532217308afcd 263 Gene3D G3DSA:3.60.20.10 1 244 1.7E-65 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_12070 d26e2e4e746217a64c3532217308afcd 263 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 235 47.621 T 12-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 TL08_12070 d26e2e4e746217a64c3532217308afcd 263 Pfam PF00227 Proteasome subunit 25 188 1.2E-29 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TL08_12070 d26e2e4e746217a64c3532217308afcd 263 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 231 3.5E-105 T 12-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 TL08_19290 bdb8eca7bd4d03bf83d48ae1cf0c37cf 94 SUPERFAMILY SSF55594 3 90 4.71E-18 T 12-10-2018 IPR035895 HPr-like superfamily TL08_19290 bdb8eca7bd4d03bf83d48ae1cf0c37cf 94 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 5.1E-21 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_19290 bdb8eca7bd4d03bf83d48ae1cf0c37cf 94 PRINTS PR00107 Phosphocarrier protein signature 58 75 9.3E-11 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_19290 bdb8eca7bd4d03bf83d48ae1cf0c37cf 94 PRINTS PR00107 Phosphocarrier protein signature 43 58 9.3E-11 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_19290 bdb8eca7bd4d03bf83d48ae1cf0c37cf 94 PRINTS PR00107 Phosphocarrier protein signature 13 29 9.3E-11 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_19290 bdb8eca7bd4d03bf83d48ae1cf0c37cf 94 Gene3D G3DSA:3.30.1340.10 1 90 1.1E-19 T 12-10-2018 IPR035895 HPr-like superfamily TL08_19290 bdb8eca7bd4d03bf83d48ae1cf0c37cf 94 Pfam PF00381 PTS HPr component phosphorylation site 4 83 1.7E-20 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_19290 bdb8eca7bd4d03bf83d48ae1cf0c37cf 94 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TL08_17370 e0f2b4e0c2b6a368100da98387a3796a 391 SUPERFAMILY SSF75005 36 333 2.71E-56 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_17370 e0f2b4e0c2b6a368100da98387a3796a 391 Pfam PF04616 Glycosyl hydrolases family 43 37 332 1.8E-51 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 TL08_17370 e0f2b4e0c2b6a368100da98387a3796a 391 Gene3D G3DSA:2.115.10.20 28 339 8.0E-79 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_22005 2409b522255045eda3eea94bd3ba1212 327 Gene3D G3DSA:1.20.1050.10 165 327 3.9E-70 T 12-10-2018 TL08_22005 2409b522255045eda3eea94bd3ba1212 327 SUPERFAMILY SSF47616 151 288 4.73E-32 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily TL08_22005 2409b522255045eda3eea94bd3ba1212 327 SUPERFAMILY SSF52833 25 144 1.39E-7 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_22005 2409b522255045eda3eea94bd3ba1212 327 Pfam PF13410 Glutathione S-transferase, C-terminal domain 191 259 1.5E-10 T 12-10-2018 TL08_22005 2409b522255045eda3eea94bd3ba1212 327 PIRSF PIRSF015753 2 309 4.9E-112 T 12-10-2018 IPR016639 Glutathione S-transferase Omega/GSH GO:0004364 TL08_22005 2409b522255045eda3eea94bd3ba1212 327 Pfam PF13409 Glutathione S-transferase, N-terminal domain 49 137 3.0E-11 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TL08_22005 2409b522255045eda3eea94bd3ba1212 327 Gene3D G3DSA:3.40.30.130 2 164 4.1E-60 T 12-10-2018 TL08_02490 bd04b0104702dc95c6e35c27c9dbde47 371 Gene3D G3DSA:3.40.50.1100 49 155 2.1E-68 T 12-10-2018 TL08_02490 bd04b0104702dc95c6e35c27c9dbde47 371 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 33 313 3.3E-47 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_02490 bd04b0104702dc95c6e35c27c9dbde47 371 SUPERFAMILY SSF53686 21 334 8.77E-73 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_02490 bd04b0104702dc95c6e35c27c9dbde47 371 Gene3D G3DSA:3.40.50.1100 34 321 2.1E-68 T 12-10-2018 TL08_20420 965b07baafcfca5d0820d6f913ec1343 385 Pfam PF06187 Protein of unknown function (DUF993) 3 383 5.8E-183 T 12-10-2018 IPR009334 Protein of unknown function DUF993 TL08_20420 965b07baafcfca5d0820d6f913ec1343 385 Gene3D G3DSA:3.20.20.500 1 379 1.0E-176 T 12-10-2018 TL08_20420 965b07baafcfca5d0820d6f913ec1343 385 SUPERFAMILY SSF51569 56 331 2.72E-12 T 12-10-2018 TL08_08265 a5604e7e2392400cb005e20078a0aafa 327 Gene3D G3DSA:3.40.50.300 3 127 4.0E-11 T 12-10-2018 TL08_08265 a5604e7e2392400cb005e20078a0aafa 327 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 9 317 2.7E-28 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 TL08_08265 a5604e7e2392400cb005e20078a0aafa 327 Gene3D G3DSA:1.20.272.10 201 325 2.7E-16 T 12-10-2018 TL08_08265 a5604e7e2392400cb005e20078a0aafa 327 Pfam PF06144 DNA polymerase III, delta subunit 13 173 1.1E-7 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 TL08_08265 a5604e7e2392400cb005e20078a0aafa 327 SUPERFAMILY SSF52540 5 175 1.35E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08265 a5604e7e2392400cb005e20078a0aafa 327 SUPERFAMILY SSF48019 203 317 5.61E-12 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TL08_21810 9ebddb036ccebfcb821fb6debbf52647 237 Pfam PF11241 Protein of unknown function (DUF3043) 56 222 2.7E-58 T 12-10-2018 IPR021403 Protein of unknown function DUF3043 TL08_00675 ad859cc2c1d1db9a76100c0812a8cf50 228 Gene3D G3DSA:3.90.550.10 3 225 1.2E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00675 ad859cc2c1d1db9a76100c0812a8cf50 228 SUPERFAMILY SSF53448 5 209 8.63E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00675 ad859cc2c1d1db9a76100c0812a8cf50 228 Pfam PF00535 Glycosyl transferase family 2 9 132 3.9E-23 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_16650 149369bd6f29da1db0659058015940d0 285 Pfam PF00296 Luciferase-like monooxygenase 32 238 2.5E-39 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_16650 149369bd6f29da1db0659058015940d0 285 Gene3D G3DSA:3.20.20.30 2 284 1.5E-55 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_16650 149369bd6f29da1db0659058015940d0 285 SUPERFAMILY SSF51679 8 282 6.28E-53 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 Gene3D G3DSA:3.40.50.300 49 260 3.2E-40 T 12-10-2018 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 Pfam PF13481 AAA domain 46 204 8.5E-17 T 12-10-2018 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 SUPERFAMILY SSF52540 53 271 7.6E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 SUPERFAMILY SSF54211 237 433 2.66E-30 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 PRINTS PR01874 DNA repair protein radA signature 106 123 3.9E-73 T 12-10-2018 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 PRINTS PR01874 DNA repair protein radA signature 195 223 3.9E-73 T 12-10-2018 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 PRINTS PR01874 DNA repair protein radA signature 304 327 3.9E-73 T 12-10-2018 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 PRINTS PR01874 DNA repair protein radA signature 156 180 3.9E-73 T 12-10-2018 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 PRINTS PR01874 DNA repair protein radA signature 230 256 3.9E-73 T 12-10-2018 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 PRINTS PR01874 DNA repair protein radA signature 63 91 3.9E-73 T 12-10-2018 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 Pfam PF13541 Subunit ChlI of Mg-chelatase 350 410 5.1E-7 T 12-10-2018 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 SMART SM00382 71 226 1.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 Hamap MF_01498 DNA repair protein RadA [radA]. 5 435 42.556 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 TIGRFAM TIGR00416 sms: DNA repair protein RadA 2 411 1.2E-146 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 TL08_01780 d96fff44568240801a994f6ec0c9ed3e 438 Gene3D G3DSA:3.30.230.10 307 420 3.2E-12 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 Pfam PF00072 Response regulator receiver domain 9 119 3.0E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 SMART SM00448 6 119 4.0E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 Gene3D G3DSA:3.40.50.12740 6 218 6.7E-67 T 12-10-2018 TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 SUPERFAMILY SSF52172 4 146 8.4E-37 T 12-10-2018 IPR011006 CheY-like superfamily TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 SUPERFAMILY SSF46894 149 219 8.16E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 SMART SM00421 155 212 4.7E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 208 4.4E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 3.5E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 3.5E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15055 73e7e5190533f11f9deb9e5e5fc5755e 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 3.5E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_16565 ce2ac5e8c64a4ccd948bba1c18e54bfb 176 SUPERFAMILY SSF47598 112 174 7.41E-8 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 Gene3D G3DSA:1.10.1060.10 16 152 5.9E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 Gene3D G3DSA:3.50.50.60 153 288 2.2E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 PRINTS PR00419 Adrenodoxin reductase family signature 178 191 4.0E-24 T 12-10-2018 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 4.0E-24 T 12-10-2018 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 PRINTS PR00419 Adrenodoxin reductase family signature 155 177 4.0E-24 T 12-10-2018 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 PRINTS PR00419 Adrenodoxin reductase family signature 220 230 4.0E-24 T 12-10-2018 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 SUPERFAMILY SSF51971 382 479 2.59E-11 T 12-10-2018 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 488 2.2E-187 T 12-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 SUPERFAMILY SSF46548 6 164 5.23E-30 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 38 141 2.4E-19 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 Gene3D G3DSA:3.50.50.60 289 480 9.3E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 SUPERFAMILY SSF51971 153 415 1.88E-63 T 12-10-2018 TL08_17880 cfb34e7c4d8e24199e6f8a911922f1e5 501 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 154 470 1.9E-28 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_03860 342abadbd40547b986b57b936de23704 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 3.0E-133 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_03860 342abadbd40547b986b57b936de23704 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 1.9E-58 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TL08_03860 342abadbd40547b986b57b936de23704 406 SUPERFAMILY SSF53901 3 281 1.08E-65 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_03860 342abadbd40547b986b57b936de23704 406 Gene3D G3DSA:3.40.47.10 2 405 2.3E-129 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_03860 342abadbd40547b986b57b936de23704 406 PIRSF PIRSF000429 1 406 2.2E-126 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_03860 342abadbd40547b986b57b936de23704 406 Pfam PF02803 Thiolase, C-terminal domain 282 404 6.0E-47 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TL08_03860 342abadbd40547b986b57b936de23704 406 SUPERFAMILY SSF53901 283 404 1.92E-43 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_03860 342abadbd40547b986b57b936de23704 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TL08_20880 6b3755b29105020bade7cc1c053740ac 61 Pfam PF04149 Domain of unknown function (DUF397) 5 56 2.4E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_09165 f6a36e6c5dafe9ca96adc1f32a6d3eae 214 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 26 172 20.99 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 TL08_09165 f6a36e6c5dafe9ca96adc1f32a6d3eae 214 SUPERFAMILY SSF75420 30 108 1.27E-16 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily TL08_09165 f6a36e6c5dafe9ca96adc1f32a6d3eae 214 Gene3D G3DSA:3.30.300.70 22 105 6.2E-13 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily TL08_09165 f6a36e6c5dafe9ca96adc1f32a6d3eae 214 Pfam PF02576 RimP N-terminal domain 31 108 3.2E-16 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal TL08_09165 f6a36e6c5dafe9ca96adc1f32a6d3eae 214 Pfam PF17384 RimP C-terminal SH3 domain 111 172 1.2E-7 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal TL08_11800 92368e94d4aa89aa902fa15775fff8f4 323 Pfam PF13412 Winged helix-turn-helix DNA-binding 85 120 2.1E-5 T 12-10-2018 TL08_11800 92368e94d4aa89aa902fa15775fff8f4 323 Gene3D G3DSA:1.10.10.10 75 158 5.4E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11800 92368e94d4aa89aa902fa15775fff8f4 323 SUPERFAMILY SSF46785 77 261 2.01E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_04535 e1b1ce6d4bc4261e80a86390ebbf2e16 175 Pfam PF05103 DivIVA protein 56 111 1.2E-6 T 12-10-2018 IPR007793 DivIVA family TL08_04535 e1b1ce6d4bc4261e80a86390ebbf2e16 175 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 56 88 3.4E-12 T 12-10-2018 IPR019933 DivIVA domain TL08_22485 bb875e342679e46efa9cb727cadaca56 217 SMART SM01006 47 94 6.2E-10 T 12-10-2018 IPR019432 Siderophore biosynthesis protein, conserved domain TL08_22485 bb875e342679e46efa9cb727cadaca56 217 SUPERFAMILY SSF55729 26 206 4.91E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_22485 bb875e342679e46efa9cb727cadaca56 217 Pfam PF13523 Acetyltransferase (GNAT) domain 52 194 1.0E-40 T 12-10-2018 TL08_22485 bb875e342679e46efa9cb727cadaca56 217 Gene3D G3DSA:3.40.630.30 6 208 1.6E-49 T 12-10-2018 TL08_01675 534760339d175107f4009af41de95450 280 SUPERFAMILY SSF51717 11 275 3.14E-92 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_01675 534760339d175107f4009af41de95450 280 Gene3D G3DSA:3.20.20.20 2 278 6.3E-106 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_01675 534760339d175107f4009af41de95450 280 Pfam PF00809 Pterin binding enzyme 15 259 2.3E-85 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_01675 534760339d175107f4009af41de95450 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 47 60 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_01675 534760339d175107f4009af41de95450 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 13 28 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_01675 534760339d175107f4009af41de95450 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 273 9.0E-92 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TL08_26665 6b0a1d314881a34ae4dc6b1da519b7fd 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_26665 6b0a1d314881a34ae4dc6b1da519b7fd 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_26665 6b0a1d314881a34ae4dc6b1da519b7fd 199 Gene3D G3DSA:1.10.357.10 3 198 5.5E-50 T 12-10-2018 TL08_26665 6b0a1d314881a34ae4dc6b1da519b7fd 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.4E-19 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_26665 6b0a1d314881a34ae4dc6b1da519b7fd 199 SUPERFAMILY SSF46689 5 89 2.15E-21 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_15735 8f3da08b67bb0ea44622c9cbb61a061e 246 Gene3D G3DSA:3.40.50.1820 2 242 4.6E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15735 8f3da08b67bb0ea44622c9cbb61a061e 246 SUPERFAMILY SSF53474 6 242 1.36E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15735 8f3da08b67bb0ea44622c9cbb61a061e 246 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 1.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_15735 8f3da08b67bb0ea44622c9cbb61a061e 246 PRINTS PR00111 Alpha/beta hydrolase fold signature 79 92 1.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_15735 8f3da08b67bb0ea44622c9cbb61a061e 246 PRINTS PR00111 Alpha/beta hydrolase fold signature 188 202 1.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_15735 8f3da08b67bb0ea44622c9cbb61a061e 246 PRINTS PR00111 Alpha/beta hydrolase fold signature 36 51 1.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_15735 8f3da08b67bb0ea44622c9cbb61a061e 246 Pfam PF12697 Alpha/beta hydrolase family 13 236 6.5E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_03865 d7ec895ece94d1a62864ed0ec1e79ac4 329 SUPERFAMILY SSF52266 99 288 2.5E-25 T 12-10-2018 TL08_03865 d7ec895ece94d1a62864ed0ec1e79ac4 329 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 100 276 3.6E-18 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain TL08_03865 d7ec895ece94d1a62864ed0ec1e79ac4 329 Gene3D G3DSA:3.40.50.1110 99 290 9.2E-18 T 12-10-2018 IPR036514 SGNH hydrolase superfamily TL08_22845 4b772b32df9f7cea52c335c10ca4210a 178 Gene3D G3DSA:3.40.630.30 1 175 4.6E-31 T 12-10-2018 TL08_22845 4b772b32df9f7cea52c335c10ca4210a 178 Pfam PF00583 Acetyltransferase (GNAT) family 39 146 9.9E-17 T 12-10-2018 IPR000182 GNAT domain TL08_22845 4b772b32df9f7cea52c335c10ca4210a 178 SUPERFAMILY SSF55729 8 153 9.26E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_26415 d2690ae6b0e990f37312232da2d02907 142 SUPERFAMILY SSF46955 18 102 3.39E-18 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_26415 d2690ae6b0e990f37312232da2d02907 142 Gene3D G3DSA:1.10.1660.10 14 108 4.0E-22 T 12-10-2018 TL08_26415 d2690ae6b0e990f37312232da2d02907 142 SMART SM00422 17 86 4.1E-23 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26415 d2690ae6b0e990f37312232da2d02907 142 Pfam PF13411 MerR HTH family regulatory protein 19 84 1.4E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26415 d2690ae6b0e990f37312232da2d02907 142 ProSitePatterns PS00552 MerR-type HTH domain signature. 20 42 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_08570 8b3cafa3d851440854f309011266693f 472 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 54 414 9.8E-132 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 TL08_08570 8b3cafa3d851440854f309011266693f 472 PIRSF PIRSF006809 45 471 3.5E-155 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 TL08_08570 8b3cafa3d851440854f309011266693f 472 PIRSF PIRSF006809 4 51 410.0 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 TL08_08570 8b3cafa3d851440854f309011266693f 472 Hamap MF_00900 GTPase HflX [hflX]. 73 444 48.637 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 TL08_08570 8b3cafa3d851440854f309011266693f 472 Gene3D G3DSA:3.40.50.300 249 418 2.1E-39 T 12-10-2018 TL08_08570 8b3cafa3d851440854f309011266693f 472 SUPERFAMILY SSF52540 250 425 2.62E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08570 8b3cafa3d851440854f309011266693f 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 319 337 3.5E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_08570 8b3cafa3d851440854f309011266693f 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 252 272 3.5E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_08570 8b3cafa3d851440854f309011266693f 472 Pfam PF16360 GTP-binding GTPase Middle Region 160 244 1.6E-29 T 12-10-2018 IPR032305 GTP-binding protein, middle domain TL08_08570 8b3cafa3d851440854f309011266693f 472 Pfam PF13167 GTP-binding GTPase N-terminal 70 158 2.5E-33 T 12-10-2018 IPR025121 GTPase HflX, N-terminal TL08_08570 8b3cafa3d851440854f309011266693f 472 Pfam PF01926 50S ribosome-binding GTPase 252 374 1.7E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_08570 8b3cafa3d851440854f309011266693f 472 Gene3D G3DSA:3.40.50.11060 64 185 1.7E-41 T 12-10-2018 TL08_08955 011696fd829d68721ec4425f2d3541f4 273 Pfam PF13312 Domain of unknown function (DUF4081) 43 145 2.3E-42 T 12-10-2018 IPR025289 Domain of unknown function DUF4081 TL08_08955 011696fd829d68721ec4425f2d3541f4 273 Pfam PF08445 FR47-like protein 201 264 1.2E-12 T 12-10-2018 IPR013653 FR47-like GO:0016747 TL08_08955 011696fd829d68721ec4425f2d3541f4 273 PIRSF PIRSF021603 1 273 3.5E-115 T 12-10-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like TL08_08955 011696fd829d68721ec4425f2d3541f4 273 Gene3D G3DSA:3.40.630.30 62 272 1.4E-20 T 12-10-2018 TL08_08955 011696fd829d68721ec4425f2d3541f4 273 SUPERFAMILY SSF55729 70 268 1.51E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_02075 aaaf2b773c6ec6258130653a73149903 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 249 2.6E-102 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TL08_02075 aaaf2b773c6ec6258130653a73149903 256 Gene3D G3DSA:3.20.20.70 1 253 8.9E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_02075 aaaf2b773c6ec6258130653a73149903 256 SUPERFAMILY SSF110399 3 241 2.22E-78 T 12-10-2018 TL08_02075 aaaf2b773c6ec6258130653a73149903 256 Hamap MF_00443 Thiazole synthase [thiG]. 4 256 40.947 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TL08_23545 55321b73b7d604ba7eb1e234652f23fc 175 Pfam PF04138 GtrA-like protein 27 157 1.2E-21 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TL08_07690 fbef7227aee93c2cb59ba4c2c18ff696 608 Gene3D G3DSA:3.40.50.620 196 368 5.3E-20 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_07690 fbef7227aee93c2cb59ba4c2c18ff696 608 SUPERFAMILY SSF52402 188 556 7.82E-30 T 12-10-2018 TL08_07690 fbef7227aee93c2cb59ba4c2c18ff696 608 Gene3D G3DSA:3.40.50.620 430 550 7.9E-6 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_07690 fbef7227aee93c2cb59ba4c2c18ff696 608 Pfam PF00733 Asparagine synthase 206 592 2.2E-37 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TL08_13195 79b0a2da66c697ed98bdd0659463abcd 242 Pfam PF02698 DUF218 domain 44 166 2.4E-22 T 12-10-2018 IPR003848 Domain of unknown function DUF218 TL08_22415 613b8730171dccf4f791696736cec761 191 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 9 184 3.3E-45 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 TL08_22415 613b8730171dccf4f791696736cec761 191 PIRSF PIRSF004553 7 189 9.3E-54 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 TL08_22415 613b8730171dccf4f791696736cec761 191 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 122 128 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TL08_22415 613b8730171dccf4f791696736cec761 191 Gene3D G3DSA:3.40.50.150 7 189 2.0E-55 T 12-10-2018 TL08_22415 613b8730171dccf4f791696736cec761 191 SUPERFAMILY SSF53335 8 185 4.53E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_22415 613b8730171dccf4f791696736cec761 191 Pfam PF03602 Conserved hypothetical protein 95 8 184 6.5E-47 T 12-10-2018 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Pfam PF04565 RNA polymerase Rpb2, domain 3 426 493 4.4E-28 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Gene3D G3DSA:2.40.270.10 29 1025 0.0 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Gene3D G3DSA:3.90.1110.10 173 361 0.0 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Gene3D G3DSA:3.90.1100.10 31 631 0.0 T 12-10-2018 TL08_02905 87a6fe949fba52c198981856830a8677 1164 SUPERFAMILY SSF64484 25 1135 0.0 T 12-10-2018 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Pfam PF10385 RNA polymerase beta subunit external 1 domain 504 570 7.0E-24 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Gene3D G3DSA:2.40.50.100 632 706 0.0 T 12-10-2018 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Pfam PF04561 RNA polymerase Rpb2, domain 2 168 367 1.4E-25 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Gene3D G3DSA:3.90.1800.10 1034 1088 1.5E-10 T 12-10-2018 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Pfam PF04560 RNA polymerase Rpb2, domain 7 1049 1123 1.1E-26 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 26 1125 12.214 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Gene3D G3DSA:2.40.50.150 742 868 0.0 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 242 844 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 ProSitePatterns PS01166 RNA polymerases beta chain signature. 870 882 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Pfam PF00562 RNA polymerase Rpb2, domain 6 631 1047 5.8E-158 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Pfam PF04563 RNA polymerase beta subunit 87 411 7.4E-22 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02905 87a6fe949fba52c198981856830a8677 1164 Gene3D G3DSA:2.30.150.10 507 574 0.0 T 12-10-2018 TL08_03980 0bedfe1fcb21623cad8af2940d0dae30 78 SUPERFAMILY SSF51735 24 64 4.6E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_03980 0bedfe1fcb21623cad8af2940d0dae30 78 Gene3D G3DSA:3.40.50.720 27 64 2.6E-20 T 12-10-2018 TL08_03980 0bedfe1fcb21623cad8af2940d0dae30 78 Gene3D G3DSA:3.90.180.10 13 26 2.6E-20 T 12-10-2018 TL08_05915 e2b5cfcd9ccd32a6a3d3cbd61cfdb734 420 Gene3D G3DSA:3.40.50.2000 217 399 5.8E-77 T 12-10-2018 TL08_05915 e2b5cfcd9ccd32a6a3d3cbd61cfdb734 420 Gene3D G3DSA:3.40.50.2000 38 416 5.8E-77 T 12-10-2018 TL08_05915 e2b5cfcd9ccd32a6a3d3cbd61cfdb734 420 Pfam PF13439 Glycosyltransferase Family 4 38 220 2.1E-21 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_05915 e2b5cfcd9ccd32a6a3d3cbd61cfdb734 420 SUPERFAMILY SSF53756 32 419 7.33E-84 T 12-10-2018 TL08_05915 e2b5cfcd9ccd32a6a3d3cbd61cfdb734 420 Pfam PF00534 Glycosyl transferases group 1 232 397 1.5E-34 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_10415 384c59910219746d8402eca3645bab82 633 SUPERFAMILY SSF52540 282 508 8.33E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10415 384c59910219746d8402eca3645bab82 633 Gene3D G3DSA:1.25.40.10 108 278 4.1E-49 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10415 384c59910219746d8402eca3645bab82 633 Pfam PF03704 Bacterial transcriptional activator domain 110 255 3.7E-45 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_10415 384c59910219746d8402eca3645bab82 633 SMART SM01043 110 255 4.4E-50 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_10415 384c59910219746d8402eca3645bab82 633 SUPERFAMILY SSF48452 106 267 1.82E-42 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10415 384c59910219746d8402eca3645bab82 633 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 77 1.5E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_10415 384c59910219746d8402eca3645bab82 633 PRINTS PR00364 Disease resistance protein signature 475 489 3.3E-6 T 12-10-2018 TL08_10415 384c59910219746d8402eca3645bab82 633 PRINTS PR00364 Disease resistance protein signature 313 328 3.3E-6 T 12-10-2018 TL08_10415 384c59910219746d8402eca3645bab82 633 PRINTS PR00364 Disease resistance protein signature 390 404 3.3E-6 T 12-10-2018 TL08_10415 384c59910219746d8402eca3645bab82 633 SMART SM00862 15 103 6.2E-4 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_10415 384c59910219746d8402eca3645bab82 633 Pfam PF00931 NB-ARC domain 294 492 5.0E-8 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_10415 384c59910219746d8402eca3645bab82 633 Gene3D G3DSA:3.40.50.300 279 434 1.3E-21 T 12-10-2018 TL08_10415 384c59910219746d8402eca3645bab82 633 Gene3D G3DSA:1.10.10.10 1 106 5.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_10415 384c59910219746d8402eca3645bab82 633 SUPERFAMILY SSF46894 2 81 2.83E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_14050 dabd3cfb09b701d90b3a89c95ffef090 798 Gene3D G3DSA:1.20.1580.10 106 373 1.0E-152 T 12-10-2018 TL08_14050 dabd3cfb09b701d90b3a89c95ffef090 798 Gene3D G3DSA:1.20.1580.10 585 623 6.1E-106 T 12-10-2018 TL08_14050 dabd3cfb09b701d90b3a89c95ffef090 798 SUPERFAMILY SSF52540 497 769 2.5E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14050 dabd3cfb09b701d90b3a89c95ffef090 798 SUPERFAMILY SSF52540 20 456 2.59E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14050 dabd3cfb09b701d90b3a89c95ffef090 798 Gene3D G3DSA:1.10.8.280 186 295 1.0E-152 T 12-10-2018 TL08_14050 dabd3cfb09b701d90b3a89c95ffef090 798 Pfam PF00005 ABC transporter 504 716 8.0E-13 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_14050 dabd3cfb09b701d90b3a89c95ffef090 798 Gene3D G3DSA:3.40.50.300 20 473 1.0E-152 T 12-10-2018 TL08_14050 dabd3cfb09b701d90b3a89c95ffef090 798 Gene3D G3DSA:3.40.50.300 498 792 6.1E-106 T 12-10-2018 TL08_20195 305f1dcde192433f59d2b3a6c126ba10 387 Gene3D G3DSA:3.30.565.10 265 383 3.1E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_20195 305f1dcde192433f59d2b3a6c126ba10 387 Pfam PF07730 Histidine kinase 189 254 3.2E-19 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_20195 305f1dcde192433f59d2b3a6c126ba10 387 SUPERFAMILY SSF55874 278 383 7.83E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_23500 9cc7954d2bc4ff3054da3da47a16e241 508 Gene3D G3DSA:3.40.50.300 8 259 8.8E-56 T 12-10-2018 TL08_23500 9cc7954d2bc4ff3054da3da47a16e241 508 Pfam PF00005 ABC transporter 280 433 6.3E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23500 9cc7954d2bc4ff3054da3da47a16e241 508 SUPERFAMILY SSF52540 14 238 3.3E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23500 9cc7954d2bc4ff3054da3da47a16e241 508 SUPERFAMILY SSF52540 255 488 2.62E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23500 9cc7954d2bc4ff3054da3da47a16e241 508 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_23500 9cc7954d2bc4ff3054da3da47a16e241 508 SMART SM00382 39 222 1.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23500 9cc7954d2bc4ff3054da3da47a16e241 508 SMART SM00382 288 482 4.6E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23500 9cc7954d2bc4ff3054da3da47a16e241 508 Pfam PF00005 ABC transporter 30 180 7.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23500 9cc7954d2bc4ff3054da3da47a16e241 508 Gene3D G3DSA:3.40.50.300 265 505 1.7E-46 T 12-10-2018 TL08_06445 1f0b2ceb7d0e318e39885d861a36b2e1 197 Pfam PF02632 BioY family 51 189 4.8E-36 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TL08_06445 1f0b2ceb7d0e318e39885d861a36b2e1 197 Gene3D G3DSA:1.10.1760.20 22 194 7.1E-49 T 12-10-2018 TL08_06445 1f0b2ceb7d0e318e39885d861a36b2e1 197 PIRSF PIRSF016661 14 197 1.5E-39 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 Gene3D G3DSA:2.40.30.10 227 327 1.0E-31 T 12-10-2018 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 SUPERFAMILY SSF50447 179 328 3.73E-32 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 SUPERFAMILY SSF52540 13 234 1.72E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 SUPERFAMILY SSF54980 330 416 1.77E-10 T 12-10-2018 IPR035647 EF-G domain III/V-like TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 159 4.7E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 Gene3D G3DSA:3.30.70.870 335 618 5.1E-116 T 12-10-2018 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 Pfam PF00679 Elongation factor G C-terminus 425 508 1.5E-21 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 16 626 1.7E-271 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 PRINTS PR00315 GTP-binding elongation factor signature 18 31 3.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 PRINTS PR00315 GTP-binding elongation factor signature 86 96 3.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 PRINTS PR00315 GTP-binding elongation factor signature 138 147 3.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 PRINTS PR00315 GTP-binding elongation factor signature 102 113 3.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 Pfam PF00009 Elongation factor Tu GTP binding domain 16 223 7.0E-51 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 Gene3D G3DSA:2.40.50.250 511 626 5.1E-116 T 12-10-2018 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 Gene3D G3DSA:3.30.70.240 418 510 5.1E-116 T 12-10-2018 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 SMART SM00838 424 512 0.0033 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 Pfam PF03144 Elongation factor Tu domain 2 247 317 1.8E-13 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 Gene3D G3DSA:3.40.50.300 14 226 4.2E-55 T 12-10-2018 TL08_04420 e62271f2e5ae28a7fba14775d2508c3d 637 SUPERFAMILY SSF54980 427 541 3.21E-27 T 12-10-2018 IPR035647 EF-G domain III/V-like TL08_20580 c352b28bc082a9736d44eeb901d55d21 373 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 18 355 7.8E-122 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TL08_20580 c352b28bc082a9736d44eeb901d55d21 373 Gene3D G3DSA:3.20.20.210 6 360 1.2E-141 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TL08_20580 c352b28bc082a9736d44eeb901d55d21 373 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 15 357 47.415 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TL08_20580 c352b28bc082a9736d44eeb901d55d21 373 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 148 164 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TL08_20580 c352b28bc082a9736d44eeb901d55d21 373 SUPERFAMILY SSF51726 18 358 4.19E-101 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TL08_20580 c352b28bc082a9736d44eeb901d55d21 373 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 31 40 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TL08_20580 c352b28bc082a9736d44eeb901d55d21 373 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 15 355 2.6E-125 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TL08_07715 f08a5b8970687f07ebb7f7c6f591b445 287 PIRSF PIRSF006648 12 287 6.1E-63 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_07715 f08a5b8970687f07ebb7f7c6f591b445 287 Pfam PF01061 ABC-2 type transporter 37 251 4.5E-32 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_07715 f08a5b8970687f07ebb7f7c6f591b445 287 PRINTS PR00164 ABC-2 type transport system membrane protein signature 56 77 1.1E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_07715 f08a5b8970687f07ebb7f7c6f591b445 287 PRINTS PR00164 ABC-2 type transport system membrane protein signature 210 229 1.1E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_07715 f08a5b8970687f07ebb7f7c6f591b445 287 PRINTS PR00164 ABC-2 type transport system membrane protein signature 230 249 1.1E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_17455 9b3da3fd990cede1fc4c502be049c495 219 Pfam PF09684 Phage tail protein (Tail_P2_I) 31 137 4.8E-14 T 12-10-2018 IPR006521 Tail protein I TL08_17455 9b3da3fd990cede1fc4c502be049c495 219 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 18 118 1.6E-26 T 12-10-2018 IPR011748 Uncharacterised protein family, phage tail-like TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 Gene3D G3DSA:3.30.70.80 43 123 4.1E-19 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 209 219 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 SUPERFAMILY SSF52743 108 404 2.75E-75 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 354 370 8.8E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 167 186 8.8E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 205 218 8.8E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 355 365 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 SUPERFAMILY SSF54897 51 122 2.66E-12 T 12-10-2018 TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 Pfam PF00082 Subtilase family 167 393 4.4E-36 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 172 183 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 Pfam PF05922 Peptidase inhibitor I9 52 123 5.4E-10 T 12-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TL08_25520 8df1c8fc73e058c1e63d2fae9a60948c 413 Gene3D G3DSA:3.40.50.200 141 411 1.9E-88 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_26545 3a84b127e7a3e097affa921671e9ecf9 339 Pfam PF01497 Periplasmic binding protein 86 313 2.2E-34 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TL08_26545 3a84b127e7a3e097affa921671e9ecf9 339 Gene3D G3DSA:3.40.50.1980 199 338 1.4E-43 T 12-10-2018 TL08_26545 3a84b127e7a3e097affa921671e9ecf9 339 SUPERFAMILY SSF53807 84 335 9.81E-44 T 12-10-2018 TL08_26545 3a84b127e7a3e097affa921671e9ecf9 339 Gene3D G3DSA:3.40.50.1980 76 198 1.1E-33 T 12-10-2018 TL08_21755 9a385d404ff231c58b7276172e394220 269 Gene3D G3DSA:1.10.760.10 9 133 2.6E-11 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TL08_21755 9a385d404ff231c58b7276172e394220 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 54 129 1.5E-6 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21755 9a385d404ff231c58b7276172e394220 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 150 223 4.8E-12 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21755 9a385d404ff231c58b7276172e394220 269 SUPERFAMILY SSF46626 135 225 1.86E-28 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TL08_21755 9a385d404ff231c58b7276172e394220 269 PIRSF PIRSF000007 1 269 2.9E-117 T 12-10-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 TL08_21755 9a385d404ff231c58b7276172e394220 269 Gene3D G3DSA:1.10.760.10 149 230 3.8E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TL08_21755 9a385d404ff231c58b7276172e394220 269 SUPERFAMILY SSF46626 23 135 1.86E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 611 628 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 SUPERFAMILY SSF51246 332 449 1.46E-36 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 2.7E-34 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 4.1E-69 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 SUPERFAMILY SSF52440 2 113 1.08E-44 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 7.0E-42 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 Gene3D G3DSA:2.40.50.100 588 654 6.8E-21 T 12-10-2018 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 SUPERFAMILY SSF51230 587 654 3.53E-19 T 12-10-2018 IPR011053 Single hybrid motif TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 SUPERFAMILY SSF56059 83 345 7.95E-62 T 12-10-2018 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 Pfam PF00364 Biotin-requiring enzyme 589 653 4.4E-15 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 SMART SM00878 337 443 6.0E-52 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_22920 c406da35c1bc1192fc9b5092e50e162b 670 Gene3D G3DSA:3.30.470.130 1 450 4.1E-182 T 12-10-2018 TL08_22995 4126e6b55f0acf315cbfc031cb608af7 388 SMART SM00382 32 210 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_22995 4126e6b55f0acf315cbfc031cb608af7 388 Gene3D G3DSA:3.40.50.300 2 240 1.7E-56 T 12-10-2018 TL08_22995 4126e6b55f0acf315cbfc031cb608af7 388 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_22995 4126e6b55f0acf315cbfc031cb608af7 388 SUPERFAMILY SSF52540 5 226 1.99E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_22995 4126e6b55f0acf315cbfc031cb608af7 388 Pfam PF00005 ABC transporter 24 162 1.9E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12460 412fae10f2e5cce7e210dc187a83a432 256 Pfam PF07729 FCD domain 100 221 2.8E-21 T 12-10-2018 IPR011711 GntR, C-terminal TL08_12460 412fae10f2e5cce7e210dc187a83a432 256 SUPERFAMILY SSF46785 13 75 6.82E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_12460 412fae10f2e5cce7e210dc187a83a432 256 SUPERFAMILY SSF48008 98 227 7.59E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_12460 412fae10f2e5cce7e210dc187a83a432 256 Gene3D G3DSA:1.10.10.10 9 72 1.2E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12460 412fae10f2e5cce7e210dc187a83a432 256 Gene3D G3DSA:1.20.120.530 97 225 3.9E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_12460 412fae10f2e5cce7e210dc187a83a432 256 SMART SM00895 100 222 4.5E-21 T 12-10-2018 IPR011711 GntR, C-terminal TL08_12460 412fae10f2e5cce7e210dc187a83a432 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 71 3.4E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_12460 412fae10f2e5cce7e210dc187a83a432 256 SMART SM00345 13 71 7.0E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_13910 ea1796c2185f99534c37ecfa35bdeb10 266 SUPERFAMILY SSF53448 14 236 1.46E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_13910 ea1796c2185f99534c37ecfa35bdeb10 266 Pfam PF00535 Glycosyl transferase family 2 20 188 6.8E-34 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_13910 ea1796c2185f99534c37ecfa35bdeb10 266 Gene3D G3DSA:3.90.550.10 2 261 2.2E-55 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_15485 660cab8b7b17fb484ce72b8bff531aa0 298 SUPERFAMILY SSF161098 33 293 1.14E-52 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15485 660cab8b7b17fb484ce72b8bff531aa0 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 287 1.1E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_15485 660cab8b7b17fb484ce72b8bff531aa0 298 Gene3D G3DSA:1.10.3720.10 32 286 9.6E-48 T 12-10-2018 IPR035906 MetI-like superfamily TL08_17920 a48c33019915a3a5e23790a23271298b 296 Pfam PF03466 LysR substrate binding domain 76 279 7.9E-36 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_17920 a48c33019915a3a5e23790a23271298b 296 Gene3D G3DSA:3.40.190.10 157 256 2.2E-38 T 12-10-2018 TL08_17920 a48c33019915a3a5e23790a23271298b 296 SUPERFAMILY SSF46785 1 99 8.84E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17920 a48c33019915a3a5e23790a23271298b 296 Gene3D G3DSA:3.40.190.10 81 266 2.2E-38 T 12-10-2018 TL08_17920 a48c33019915a3a5e23790a23271298b 296 SUPERFAMILY SSF53850 77 284 7.78E-33 T 12-10-2018 TL08_17920 a48c33019915a3a5e23790a23271298b 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 50 1.6E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_17920 a48c33019915a3a5e23790a23271298b 296 Gene3D G3DSA:1.10.10.10 1 80 5.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25690 03e337d44addbfce767c4cc534614c1c 505 Pfam PF02397 Bacterial sugar transferase 311 499 1.9E-67 T 12-10-2018 IPR003362 Bacterial sugar transferase TL08_25690 03e337d44addbfce767c4cc534614c1c 505 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 50 505 2.5E-125 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase TL08_25690 03e337d44addbfce767c4cc534614c1c 505 Pfam PF13727 CoA-binding domain 106 240 2.8E-8 T 12-10-2018 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 218 408 1.3E-71 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 Gene3D G3DSA:3.40.50.10990 217 388 4.1E-74 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 PIRSF PIRSF001259 10 414 6.7E-178 T 12-10-2018 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 Gene3D G3DSA:3.90.870.10 6 216 1.1E-89 T 12-10-2018 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 10 214 38.226 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 210 3.2E-73 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 SUPERFAMILY SSF142695 216 387 4.32E-71 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 215 411 40.801 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 11 407 55.345 T 12-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 SUPERFAMILY SSF55821 13 217 5.49E-81 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 Pfam PF00925 GTP cyclohydrolase II 218 384 5.1E-71 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TL08_11585 9625fb79cf648ea112f721b1e27871f3 428 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 16 209 9.5E-85 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_27055 ca3a71ef2a878453f38266d0fb0b7635 156 PRINTS PR00502 NUDIX hydrolase family signature 32 46 4.8E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_27055 ca3a71ef2a878453f38266d0fb0b7635 156 PRINTS PR00502 NUDIX hydrolase family signature 46 61 4.8E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_27055 ca3a71ef2a878453f38266d0fb0b7635 156 Gene3D G3DSA:3.90.79.10 1 139 7.4E-32 T 12-10-2018 TL08_27055 ca3a71ef2a878453f38266d0fb0b7635 156 Pfam PF00293 NUDIX domain 20 130 1.8E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_27055 ca3a71ef2a878453f38266d0fb0b7635 156 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_27055 ca3a71ef2a878453f38266d0fb0b7635 156 SUPERFAMILY SSF55811 20 133 3.52E-30 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 Gene3D G3DSA:1.20.1050.60 418 510 3.0E-203 T 12-10-2018 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 Gene3D G3DSA:3.60.21.10 1098 1424 8.2E-28 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 SUPERFAMILY SSF48208 328 712 3.74E-12 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 Gene3D G3DSA:2.60.40.380 1000 1096 1.1E-6 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 Gene3D G3DSA:3.30.2080.10 364 787 3.0E-203 T 12-10-2018 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 Pfam PF00149 Calcineurin-like phosphoesterase 1101 1332 2.1E-15 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 Gene3D G3DSA:2.70.98.10 64 417 3.0E-203 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 SUPERFAMILY SSF56300 1100 1407 2.92E-37 T 12-10-2018 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 SUPERFAMILY SSF49363 983 1094 1.96E-17 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 Gene3D G3DSA:1.20.1610.10 511 659 3.0E-203 T 12-10-2018 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 37 787 4.8E-123 T 12-10-2018 IPR005887 Alpha-1,2-mannosidase, putative TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 1001 1093 2.5E-18 T 12-10-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 TL08_16405 ed27be14d260585efaaffca4b5a5f52a 1457 Pfam PF07971 Glycosyl hydrolase family 92 308 784 1.3E-128 T 12-10-2018 IPR012939 Glycosyl hydrolase family 92 TL08_10580 092b548035c31680bd7ead3476e5e177 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 143 21.97 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TL08_10580 092b548035c31680bd7ead3476e5e177 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 141 3.1E-22 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TL08_10580 092b548035c31680bd7ead3476e5e177 143 SMART SM00649 11 142 1.1E-39 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TL08_10580 092b548035c31680bd7ead3476e5e177 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 42 74 9.0E-4 T 12-10-2018 TL08_10580 092b548035c31680bd7ead3476e5e177 143 SUPERFAMILY SSF54747 13 85 2.22E-11 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TL08_10580 092b548035c31680bd7ead3476e5e177 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 128 143 - T 12-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_10580 092b548035c31680bd7ead3476e5e177 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 13 67 1.8E-9 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal TL08_10580 092b548035c31680bd7ead3476e5e177 143 Gene3D G3DSA:3.30.1550.10 6 73 5.0E-12 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TL08_10580 092b548035c31680bd7ead3476e5e177 143 Gene3D G3DSA:1.10.10.250 74 142 3.3E-24 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TL08_10580 092b548035c31680bd7ead3476e5e177 143 SUPERFAMILY SSF46906 69 142 1.24E-20 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 Gene3D G3DSA:3.30.70.920 58 138 6.4E-20 T 12-10-2018 TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 SMART SM00344 5 112 3.2E-38 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 SUPERFAMILY SSF46785 4 71 1.99E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 3.0E-18 T 12-10-2018 TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 Gene3D G3DSA:1.10.10.10 6 57 8.3E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 2.5E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 2.5E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 2.5E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 SMART SM00418 3 89 0.0038 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 SUPERFAMILY SSF54909 66 144 1.74E-13 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_12140 2bf468c711c7b03985b0051550b32c5f 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 141 7.8E-14 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TL08_12775 de2292169146982407adf2bfa704f77d 284 Gene3D G3DSA:1.10.3720.10 76 280 1.2E-17 T 12-10-2018 IPR035906 MetI-like superfamily TL08_12775 de2292169146982407adf2bfa704f77d 284 SUPERFAMILY SSF161098 81 268 4.19E-23 T 12-10-2018 IPR035906 MetI-like superfamily TL08_12775 de2292169146982407adf2bfa704f77d 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 277 2.5E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_05280 71dd5c19cabadd9b135d5dbd6e965da7 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 258 303 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TL08_05280 71dd5c19cabadd9b135d5dbd6e965da7 319 SMART SM00342 222 307 2.7E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_05280 71dd5c19cabadd9b135d5dbd6e965da7 319 Pfam PF12833 Helix-turn-helix domain 228 307 1.5E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_05280 71dd5c19cabadd9b135d5dbd6e965da7 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 276 291 1.5E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_05280 71dd5c19cabadd9b135d5dbd6e965da7 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 291 307 1.5E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_05280 71dd5c19cabadd9b135d5dbd6e965da7 319 Pfam PF14525 AraC-binding-like domain 19 190 3.4E-13 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like TL08_05280 71dd5c19cabadd9b135d5dbd6e965da7 319 SUPERFAMILY SSF46689 258 309 3.05E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_05280 71dd5c19cabadd9b135d5dbd6e965da7 319 Gene3D G3DSA:1.10.10.60 201 312 7.5E-24 T 12-10-2018 TL08_04170 1ee4b2df88eb59d876351819b83afa54 355 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 26 337 1.5E-114 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TL08_04170 1ee4b2df88eb59d876351819b83afa54 355 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 26 333 2.7E-143 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TL08_04170 1ee4b2df88eb59d876351819b83afa54 355 Gene3D G3DSA:3.40.190.90 146 307 9.5E-133 T 12-10-2018 TL08_04170 1ee4b2df88eb59d876351819b83afa54 355 PIRSF PIRSF004532 24 344 1.8E-148 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TL08_04170 1ee4b2df88eb59d876351819b83afa54 355 Gene3D G3DSA:3.30.540.10 30 333 9.5E-133 T 12-10-2018 TL08_04170 1ee4b2df88eb59d876351819b83afa54 355 SUPERFAMILY SSF56655 24 336 2.02E-113 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.50.720 1227 1704 1.6E-114 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.50.720 4676 5141 1.2E-123 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF14765 Polyketide synthase dehydratase 4370 4672 1.0E-46 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF14765 Polyketide synthase dehydratase 950 1221 2.8E-54 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00550 Phosphopantetheine attachment site 5162 5228 6.8E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00550 Phosphopantetheine attachment site 3336 3401 2.6E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00550 Phosphopantetheine attachment site 1729 1794 8.3E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF55048 4111 4176 2.75E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF51735 2817 3025 4.72E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM01294 3334 3401 1.3E-7 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM01294 5161 5228 6.9E-7 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM01294 1731 1794 5.8E-5 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.30.70.3290 498 930 1.8E-156 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:1.10.1200.10 3315 3407 2.7E-32 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:1.10.1200.10 5144 5234 4.3E-33 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2071 2188 1.2E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 409 1.1E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3680 3797 3.0E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF47336 3327 3438 5.76E-23 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF53901 32 407 3.08E-99 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF55048 707 770 2.09E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.30.70.3290 2263 2347 1.9E-74 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.30.70.3290 2711 2756 6.9E-59 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF51735 4681 4863 2.72E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF53901 3421 3794 3.19E-99 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF51735 1232 1425 3.9E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.30.70.3290 3871 4351 1.8E-145 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1441 1621 1.6E-52 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3048 3227 1.8E-57 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4877 5057 2.1E-64 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3423 3672 2.2E-89 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1818 2063 3.0E-87 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 8.6E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.366.10 2521 2710 6.9E-59 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF51735 1439 1621 2.26E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1753 1768 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF53901 1815 2185 3.26E-103 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.366.10 3957 4307 1.8E-145 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.366.10 583 885 1.8E-156 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.366.10 2348 2495 1.9E-74 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00823 Phosphopantetheine attachment site 5160 5232 3.6E-32 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00823 Phosphopantetheine attachment site 1726 1798 6.4E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00823 Phosphopantetheine attachment site 3333 3405 4.0E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF51735 3045 3273 7.66E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00826 950 1112 1.6E-70 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00826 4370 4556 1.8E-47 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00825 Beta-ketoacyl synthase 3425 3850 5.3E-223 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00825 Beta-ketoacyl synthase 1819 2241 1.4E-225 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00825 Beta-ketoacyl synthase 37 462 3.0E-212 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1976 1992 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF52151 581 868 3.92E-65 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:1.10.1200.10 1706 1798 1.5E-31 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF55048 2520 2571 3.27E-7 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.50.720 2771 3298 3.6E-165 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.47.10 3415 3867 9.0E-189 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.47.10 26 488 4.3E-184 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.40.47.10 1812 2262 8.4E-185 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5187 5202 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2191 2310 8.1E-17 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 549 1.3E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3800 3921 2.0E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2350 2707 6.5E-86 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 585 882 1.6E-101 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3959 4304 6.5E-111 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF47336 1725 1832 1.05E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF52151 2347 2659 6.02E-60 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF52151 3955 4271 1.23E-67 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF08659 KR domain 3048 3225 2.9E-59 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF08659 KR domain 4877 5056 1.8E-62 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF08659 KR domain 1441 1619 4.0E-56 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF47336 5155 5232 6.67E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.10.129.110 939 1226 3.6E-105 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Gene3D G3DSA:3.10.129.110 4359 4675 7.0E-92 T 12-10-2018 TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3585 3601 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00698 Acyl transferase domain 2349 2487 5.1E-42 T 12-10-2018 IPR014043 Acyl transferase TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00698 Acyl transferase domain 583 900 1.3E-81 T 12-10-2018 IPR014043 Acyl transferase TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00698 Acyl transferase domain 2529 2690 1.4E-21 T 12-10-2018 IPR014043 Acyl transferase TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 Pfam PF00698 Acyl transferase domain 3959 4273 7.8E-56 T 12-10-2018 IPR014043 Acyl transferase TL08_15925 7516a7a3679c3808b8a5f87b142e4dae 5314 SUPERFAMILY SSF51735 4876 5132 1.01E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 SUPERFAMILY SSF75620 11 351 1.57E-121 T 12-10-2018 TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 Gene3D G3DSA:3.30.70.1660 106 340 1.2E-92 T 12-10-2018 TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 Pfam PF03462 PCRF domain 12 202 8.6E-64 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 2 355 37.022 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 353 1.4E-146 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 Gene3D G3DSA:1.20.58.410 3 97 2.2E-6 T 12-10-2018 TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 Pfam PF00472 RF-1 domain 210 319 1.8E-37 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 Gene3D G3DSA:3.30.160.20 209 295 1.2E-92 T 12-10-2018 TL08_07270 825c6c18bbcb8aa68fdde5ceef41fe3c 358 SMART SM00937 64 177 3.0E-52 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 TL08_04580 5c6d52242c65ccdf909121276065bd37 285 Gene3D G3DSA:1.10.260.40 10 74 8.9E-15 T 12-10-2018 TL08_04580 5c6d52242c65ccdf909121276065bd37 285 SMART SM00530 16 71 2.3E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_04580 5c6d52242c65ccdf909121276065bd37 285 Pfam PF13560 Helix-turn-helix domain 12 72 3.1E-13 T 12-10-2018 TL08_04580 5c6d52242c65ccdf909121276065bd37 285 SUPERFAMILY SSF47413 12 71 9.29E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_06300 1f66ade5c16a1d8ca7a81af76354a60f 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 93 9.7E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_06300 1f66ade5c16a1d8ca7a81af76354a60f 325 Pfam PF00107 Zinc-binding dehydrogenase 154 267 2.9E-18 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_06300 1f66ade5c16a1d8ca7a81af76354a60f 325 SUPERFAMILY SSF50129 2 156 4.4E-23 T 12-10-2018 IPR011032 GroES-like superfamily TL08_06300 1f66ade5c16a1d8ca7a81af76354a60f 325 SUPERFAMILY SSF51735 116 267 2.56E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_06300 1f66ade5c16a1d8ca7a81af76354a60f 325 Gene3D G3DSA:3.40.50.720 127 270 1.3E-71 T 12-10-2018 TL08_06300 1f66ade5c16a1d8ca7a81af76354a60f 325 Gene3D G3DSA:3.90.180.10 10 319 1.3E-71 T 12-10-2018 TL08_06300 1f66ade5c16a1d8ca7a81af76354a60f 325 SMART SM00829 10 323 3.3E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_09890 bee0632bbbd7d2ead88b89f1a4323648 395 SUPERFAMILY SSF53474 125 377 9.99E-10 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_09890 bee0632bbbd7d2ead88b89f1a4323648 395 Pfam PF06259 Alpha/beta hydrolase 147 332 9.1E-47 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 TL08_25790 a0504b0e0ef6412e2e01674c81762cdf 737 SUPERFAMILY SSF52540 97 325 2.3E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25790 a0504b0e0ef6412e2e01674c81762cdf 737 Pfam PF00931 NB-ARC domain 103 332 9.8E-7 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_25790 a0504b0e0ef6412e2e01674c81762cdf 737 Gene3D G3DSA:1.25.40.10 507 734 1.4E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_25790 a0504b0e0ef6412e2e01674c81762cdf 737 Gene3D G3DSA:3.40.50.300 85 222 7.2E-13 T 12-10-2018 TL08_25790 a0504b0e0ef6412e2e01674c81762cdf 737 SUPERFAMILY SSF48452 523 665 2.98E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17050 932b5eb0f8fb9d06c9d067ae059777fa 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 290 4.1E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_17050 932b5eb0f8fb9d06c9d067ae059777fa 291 SUPERFAMILY SSF161098 85 274 5.76E-29 T 12-10-2018 IPR035906 MetI-like superfamily TL08_17050 932b5eb0f8fb9d06c9d067ae059777fa 291 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 60 9.0E-11 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TL08_17050 932b5eb0f8fb9d06c9d067ae059777fa 291 Gene3D G3DSA:1.10.3720.10 80 286 9.6E-24 T 12-10-2018 IPR035906 MetI-like superfamily TL08_18110 d0d0fc91e239ea77da4341f515487697 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 258 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_18110 d0d0fc91e239ea77da4341f515487697 406 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 18 396 68.611 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TL08_18110 d0d0fc91e239ea77da4341f515487697 406 Gene3D G3DSA:3.40.640.10 62 303 2.7E-142 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_18110 d0d0fc91e239ea77da4341f515487697 406 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 19 393 3.4E-144 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TL08_18110 d0d0fc91e239ea77da4341f515487697 406 SUPERFAMILY SSF53383 20 393 2.26E-125 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_18110 d0d0fc91e239ea77da4341f515487697 406 Gene3D G3DSA:3.90.1150.10 28 384 2.7E-142 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_18110 d0d0fc91e239ea77da4341f515487697 406 Pfam PF00202 Aminotransferase class-III 26 389 3.2E-113 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_18110 d0d0fc91e239ea77da4341f515487697 406 PIRSF PIRSF000521 19 131 1.4E-11 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_18110 d0d0fc91e239ea77da4341f515487697 406 PIRSF PIRSF000521 125 159 0.58 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_18110 d0d0fc91e239ea77da4341f515487697 406 PIRSF PIRSF000521 171 396 2.3E-32 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_18580 8498bf5bd2b5a5db83c734fad3e59171 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 276 291 1.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_18580 8498bf5bd2b5a5db83c734fad3e59171 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 291 307 1.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_18580 8498bf5bd2b5a5db83c734fad3e59171 328 Gene3D G3DSA:1.10.10.60 202 313 1.0E-24 T 12-10-2018 TL08_18580 8498bf5bd2b5a5db83c734fad3e59171 328 Pfam PF12852 Cupin 2 191 4.9E-46 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain TL08_18580 8498bf5bd2b5a5db83c734fad3e59171 328 Pfam PF12833 Helix-turn-helix domain 229 308 1.6E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_18580 8498bf5bd2b5a5db83c734fad3e59171 328 SUPERFAMILY SSF46689 259 309 2.78E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18580 8498bf5bd2b5a5db83c734fad3e59171 328 SMART SM00342 223 307 1.5E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_18580 8498bf5bd2b5a5db83c734fad3e59171 328 SUPERFAMILY SSF46689 206 256 2.26E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18580 8498bf5bd2b5a5db83c734fad3e59171 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 260 303 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TL08_11055 bc13e004c31ab7171bbf410aefc01658 417 Pfam PF13579 Glycosyl transferase 4-like domain 22 199 2.6E-28 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_11055 bc13e004c31ab7171bbf410aefc01658 417 SUPERFAMILY SSF53756 1 396 3.84E-82 T 12-10-2018 TL08_11055 bc13e004c31ab7171bbf410aefc01658 417 Gene3D G3DSA:3.40.50.2000 200 378 3.9E-103 T 12-10-2018 TL08_11055 bc13e004c31ab7171bbf410aefc01658 417 Gene3D G3DSA:3.40.50.2000 5 395 3.9E-103 T 12-10-2018 TL08_11055 bc13e004c31ab7171bbf410aefc01658 417 Pfam PF00534 Glycosyl transferases group 1 214 371 7.1E-35 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_01350 31e853672de0439818e8a2bcaaa74cb5 144 Pfam PF02575 YbaB/EbfC DNA-binding family 14 97 9.6E-11 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_01350 31e853672de0439818e8a2bcaaa74cb5 144 Gene3D G3DSA:3.30.1310.10 7 105 6.8E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_01350 31e853672de0439818e8a2bcaaa74cb5 144 SUPERFAMILY SSF82607 12 95 3.4E-8 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_26560 4d6cf8b2e35e7399ebf6a6c299a8e85b 666 SUPERFAMILY SSF49319 187 303 5.1E-7 T 12-10-2018 IPR027273 Neocarzinostatin-like TL08_26560 4d6cf8b2e35e7399ebf6a6c299a8e85b 666 SUPERFAMILY SSF49319 445 569 2.94E-11 T 12-10-2018 IPR027273 Neocarzinostatin-like TL08_26560 4d6cf8b2e35e7399ebf6a6c299a8e85b 666 SUPERFAMILY SSF49319 46 180 1.26E-10 T 12-10-2018 IPR027273 Neocarzinostatin-like TL08_26560 4d6cf8b2e35e7399ebf6a6c299a8e85b 666 Gene3D G3DSA:2.60.40.230 310 414 6.8E-10 T 12-10-2018 TL08_26560 4d6cf8b2e35e7399ebf6a6c299a8e85b 666 Pfam PF00960 Neocarzinostatin family 313 406 6.6E-9 T 12-10-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 TL08_26560 4d6cf8b2e35e7399ebf6a6c299a8e85b 666 Gene3D G3DSA:2.60.40.230 186 302 5.1E-5 T 12-10-2018 TL08_26560 4d6cf8b2e35e7399ebf6a6c299a8e85b 666 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 67 - T 12-10-2018 IPR010916 TonB box, conserved site TL08_26560 4d6cf8b2e35e7399ebf6a6c299a8e85b 666 SUPERFAMILY SSF49319 310 422 6.8E-17 T 12-10-2018 IPR027273 Neocarzinostatin-like TL08_03640 1dc62069d530a0e683f4d04ec6b9e788 321 Gene3D G3DSA:3.30.230.10 3 169 2.4E-61 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_03640 1dc62069d530a0e683f4d04ec6b9e788 321 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 9 282 7.3E-52 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TL08_03640 1dc62069d530a0e683f4d04ec6b9e788 321 PIRSF PIRSF010376 8 307 2.6E-80 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TL08_03640 1dc62069d530a0e683f4d04ec6b9e788 321 SUPERFAMILY SSF55060 173 293 9.35E-22 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TL08_03640 1dc62069d530a0e683f4d04ec6b9e788 321 Pfam PF08544 GHMP kinases C terminal 213 285 1.4E-8 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain TL08_03640 1dc62069d530a0e683f4d04ec6b9e788 321 Pfam PF00288 GHMP kinases N terminal domain 96 154 1.5E-8 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TL08_03640 1dc62069d530a0e683f4d04ec6b9e788 321 SUPERFAMILY SSF54211 8 167 1.21E-42 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_03640 1dc62069d530a0e683f4d04ec6b9e788 321 Gene3D G3DSA:3.30.70.890 170 312 7.0E-44 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TL08_03640 1dc62069d530a0e683f4d04ec6b9e788 321 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 9 298 31.28 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TL08_18365 9f5dcc8e7ad849ed30833a8b838ee10f 302 Pfam PF14100 Methane oxygenase PmoA 14 294 5.4E-75 T 12-10-2018 IPR029475 Methane oxygenase PmoA TL08_21160 a8a10a1a48b2c9d44b17ea13b746d884 405 Pfam PF04235 Protein of unknown function (DUF418) 232 394 1.9E-35 T 12-10-2018 IPR007349 Domain of unknown function DUF418 TL08_03410 3022bea2c3a39677a8dbbd1e27f2e38d 132 SUPERFAMILY SSF46689 52 101 4.03E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_03410 3022bea2c3a39677a8dbbd1e27f2e38d 132 Gene3D G3DSA:1.10.10.60 1 105 1.1E-27 T 12-10-2018 TL08_03410 3022bea2c3a39677a8dbbd1e27f2e38d 132 Pfam PF12833 Helix-turn-helix domain 22 100 1.2E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_03410 3022bea2c3a39677a8dbbd1e27f2e38d 132 SUPERFAMILY SSF46689 2 50 1.03E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_03410 3022bea2c3a39677a8dbbd1e27f2e38d 132 SMART SM00342 16 99 2.8E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_10735 77b902d7404b5d9e4f249fb26c858cb4 224 PIRSF PIRSF000847 32 218 1.6E-44 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 TL08_10735 77b902d7404b5d9e4f249fb26c858cb4 224 Gene3D G3DSA:1.20.120.1760 30 217 6.6E-11 T 12-10-2018 TL08_10735 77b902d7404b5d9e4f249fb26c858cb4 224 Pfam PF01066 CDP-alcohol phosphatidyltransferase 37 101 3.3E-15 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TL08_10735 77b902d7404b5d9e4f249fb26c858cb4 224 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 79 101 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 Gene3D G3DSA:2.40.110.10 126 239 9.1E-42 T 12-10-2018 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 SUPERFAMILY SSF47203 233 386 5.64E-58 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 Gene3D G3DSA:1.10.540.10 13 124 2.3E-40 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 PIRSF PIRSF016578 6 99 4.4E-9 T 12-10-2018 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 PIRSF PIRSF016578 130 386 2.3E-17 T 12-10-2018 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 SUPERFAMILY SSF56645 8 247 3.01E-78 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 1.7E-28 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 385 6.8E-50 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 122 2.1E-31 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 128 140 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TL08_23510 9a1c0ae102be4fe722e7d5041640c34b 387 Gene3D G3DSA:1.20.140.10 240 387 6.0E-56 T 12-10-2018 TL08_02445 31d11c808450a086f77f10b7aa0fb338 512 Gene3D G3DSA:3.30.200.20 1 62 2.7E-9 T 12-10-2018 TL08_02445 31d11c808450a086f77f10b7aa0fb338 512 Gene3D G3DSA:1.10.510.10 63 263 2.3E-42 T 12-10-2018 TL08_02445 31d11c808450a086f77f10b7aa0fb338 512 SUPERFAMILY SSF56112 1 273 2.7E-57 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_02445 31d11c808450a086f77f10b7aa0fb338 512 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 105 117 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_02445 31d11c808450a086f77f10b7aa0fb338 512 SMART SM00220 1 244 2.3E-30 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_02445 31d11c808450a086f77f10b7aa0fb338 512 Pfam PF00069 Protein kinase domain 4 233 5.4E-36 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 5.7E-33 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PIRSF PIRSF000350 1 462 9.0E-86 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 SUPERFAMILY SSF51905 1 336 4.49E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 2.3E-63 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 2.3E-63 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 2.3E-63 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 2.3E-63 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 2.3E-63 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.3E-63 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.3E-63 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 2.3E-63 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 2.3E-63 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 Gene3D G3DSA:3.30.390.30 346 466 7.0E-44 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 Gene3D G3DSA:3.50.50.60 5 332 1.5E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 Gene3D G3DSA:3.50.50.60 150 270 1.5E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 2.0E-33 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 2.0E-33 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 2.0E-33 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 2.0E-33 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.0E-33 T 12-10-2018 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 SUPERFAMILY SSF55424 343 465 6.53E-37 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 327 1.1E-64 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 466 4.5E-165 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TL08_06395 b7fd061968854dbf7a73c8955bc003d7 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 SUPERFAMILY SSF101353 249 446 4.32E-54 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 Gene3D G3DSA:3.10.310.40 772 886 3.5E-18 T 12-10-2018 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 1.5E-238 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 660 704 3.0E-15 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 SUPERFAMILY SSF55681 3 248 2.98E-87 T 12-10-2018 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 164.351 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 Gene3D G3DSA:3.30.54.20 631 685 9.8E-36 T 12-10-2018 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 Pfam PF01411 tRNA synthetases class II (A) 5 562 7.1E-193 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 Gene3D G3DSA:3.30.930.10 1 245 9.5E-92 T 12-10-2018 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 1.6E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 1.6E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 1.6E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.6E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 1.6E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 Pfam PF02272 DHHA1 domain 740 883 3.4E-16 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 Gene3D G3DSA:3.30.980.10 571 705 9.8E-36 T 12-10-2018 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 SMART SM00863 660 704 7.5E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 SUPERFAMILY SSF55186 559 719 2.09E-40 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 SUPERFAMILY SSF50447 460 559 3.39E-15 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_11360 e4ee82f2cd7ea11afe319ab39e90948a 892 Gene3D G3DSA:2.40.30.130 471 558 2.5E-9 T 12-10-2018 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 SUPERFAMILY SSF52218 492 642 6.64E-37 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 Gene3D G3DSA:3.40.50.80 886 1035 1.2E-45 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 Gene3D G3DSA:1.20.990.10 707 824 9.7E-52 T 12-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 Pfam PF00667 FAD binding domain 667 865 7.9E-27 T 12-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 Gene3D G3DSA:3.40.50.360 492 642 1.4E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 SUPERFAMILY SSF63380 663 877 1.14E-49 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 SUPERFAMILY SSF52343 885 1035 4.06E-39 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 Pfam PF00175 Oxidoreductase NAD-binding domain 898 1007 2.3E-12 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 Gene3D G3DSA:2.40.30.10 671 874 9.7E-52 T 12-10-2018 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 Gene3D G3DSA:1.10.630.10 10 479 2.0E-143 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 Pfam PF00067 Cytochrome P450 13 459 9.6E-82 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PIRSF PIRSF000209 6 1035 0.0 T 12-10-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 SUPERFAMILY SSF48264 11 464 9.43E-110 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00463 E-class P450 group I signature 43 62 2.5E-25 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00463 E-class P450 group I signature 367 391 2.5E-25 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00463 E-class P450 group I signature 327 345 2.5E-25 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00463 E-class P450 group I signature 285 311 2.5E-25 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00463 E-class P450 group I signature 265 282 2.5E-25 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00463 E-class P450 group I signature 402 412 2.5E-25 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00463 E-class P450 group I signature 412 435 2.5E-25 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 405 414 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00385 P450 superfamily signature 412 423 3.1E-10 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00385 P450 superfamily signature 403 412 3.1E-10 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00385 P450 superfamily signature 328 339 3.1E-10 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 PRINTS PR00385 P450 superfamily signature 276 293 3.1E-10 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_06025 83896717a336968cebb674ad0a95e1b0 1035 Pfam PF00258 Flavodoxin 497 619 1.3E-17 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 Pfam PF02779 Transketolase, pyrimidine binding domain 317 478 4.0E-38 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 Gene3D G3DSA:3.40.50.970 314 487 6.9E-58 T 12-10-2018 TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 SMART SM00861 317 482 2.8E-53 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 653 40.654 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 SUPERFAMILY SSF52518 311 479 1.07E-52 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 481 1.6E-157 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 Gene3D G3DSA:3.40.50.920 525 656 1.1E-27 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 SUPERFAMILY SSF52922 529 651 4.84E-25 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 Pfam PF02780 Transketolase, C-terminal domain 530 644 2.7E-26 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 280 3.7E-106 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 SUPERFAMILY SSF52518 3 348 2.44E-67 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_08450 f1f29f02af4cf81aecfdf050d4a6491d 671 ProSitePatterns PS00802 Transketolase signature 2. 423 439 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_19815 43712f4d10c110d76c0f488b92b9d81e 337 Gene3D G3DSA:3.40.47.10 16 337 1.1E-108 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_19815 43712f4d10c110d76c0f488b92b9d81e 337 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 250 337 4.6E-27 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TL08_19815 43712f4d10c110d76c0f488b92b9d81e 337 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 121 192 3.2E-21 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TL08_19815 43712f4d10c110d76c0f488b92b9d81e 337 SUPERFAMILY SSF53901 16 337 1.05E-54 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_12430 3c339588147ff7448f6d780e3b922d62 332 SUPERFAMILY SSF53822 37 312 7.07E-49 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_12430 3c339588147ff7448f6d780e3b922d62 332 Gene3D G3DSA:3.40.50.2300 143 280 4.6E-48 T 12-10-2018 TL08_12430 3c339588147ff7448f6d780e3b922d62 332 Gene3D G3DSA:3.40.50.2300 44 308 4.6E-48 T 12-10-2018 TL08_12430 3c339588147ff7448f6d780e3b922d62 332 Pfam PF13407 Periplasmic binding protein domain 40 301 5.4E-35 T 12-10-2018 IPR025997 Periplasmic binding protein TL08_24930 6400f2c2bdf9c930d492ac3b8c9d3763 96 SUPERFAMILY SSF140453 4 95 6.02E-21 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_24930 6400f2c2bdf9c930d492ac3b8c9d3763 96 Gene3D G3DSA:1.10.287.1060 1 96 1.7E-22 T 12-10-2018 TL08_24930 6400f2c2bdf9c930d492ac3b8c9d3763 96 Pfam PF06013 Proteins of 100 residues with WXG 5 89 6.0E-13 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like TL08_24930 6400f2c2bdf9c930d492ac3b8c9d3763 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 9.7E-18 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like TL08_25235 8e1b6a895415974c251cee650e50381b 128 Pfam PF00313 'Cold-shock' DNA-binding domain 4 63 4.9E-16 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_25235 8e1b6a895415974c251cee650e50381b 128 PRINTS PR00050 Cold shock protein signature 4 19 3.5E-12 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_25235 8e1b6a895415974c251cee650e50381b 128 PRINTS PR00050 Cold shock protein signature 38 56 3.5E-12 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_25235 8e1b6a895415974c251cee650e50381b 128 PRINTS PR00050 Cold shock protein signature 24 33 3.5E-12 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_25235 8e1b6a895415974c251cee650e50381b 128 SMART SM00357 3 65 2.1E-21 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 TL08_25235 8e1b6a895415974c251cee650e50381b 128 SUPERFAMILY SSF50249 3 65 9.06E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_25235 8e1b6a895415974c251cee650e50381b 128 Gene3D G3DSA:2.40.50.140 3 64 8.5E-20 T 12-10-2018 TL08_00380 b3af0842fd4ef55bcfb896cd411fe233 543 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 52 461 2.3E-57 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TL08_00380 b3af0842fd4ef55bcfb896cd411fe233 543 Pfam PF00474 Sodium:solute symporter family 52 461 6.8E-93 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TL08_00380 b3af0842fd4ef55bcfb896cd411fe233 543 Gene3D G3DSA:1.20.1730.10 39 491 2.7E-55 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 Gene3D G3DSA:1.25.40.10 91 215 1.9E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 Gene3D G3DSA:3.40.50.300 216 339 1.3E-5 T 12-10-2018 TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 SUPERFAMILY SSF46894 4 87 7.09E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 SMART SM00862 17 88 1.2E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 PRINTS PR00364 Disease resistance protein signature 235 250 1.4E-9 T 12-10-2018 TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 PRINTS PR00364 Disease resistance protein signature 297 311 1.4E-9 T 12-10-2018 TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 PRINTS PR00364 Disease resistance protein signature 380 394 1.4E-9 T 12-10-2018 TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 76 1.6E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 Pfam PF03704 Bacterial transcriptional activator domain 98 198 6.4E-19 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 SUPERFAMILY SSF52540 211 446 1.12E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 Gene3D G3DSA:1.10.10.10 1 90 2.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 SMART SM01043 77 198 5.1E-20 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_19270 08cbfc19a70f042236ea6f2a627fe191 511 SUPERFAMILY SSF48452 136 203 8.72E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 Gene3D G3DSA:3.30.70.2450 180 263 5.8E-101 T 12-10-2018 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 Pfam PF01494 FAD binding domain 5 339 2.6E-68 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 Gene3D G3DSA:3.40.30.120 395 522 4.3E-8 T 12-10-2018 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 SUPERFAMILY SSF51905 5 370 4.54E-63 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 341 1.2E-40 T 12-10-2018 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.2E-40 T 12-10-2018 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 1.2E-40 T 12-10-2018 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 1.2E-40 T 12-10-2018 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 325 1.2E-40 T 12-10-2018 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 1.2E-40 T 12-10-2018 TL08_24155 39bce423ffb598ce6a9a2a94637b4025 537 Gene3D G3DSA:3.50.50.60 7 338 5.8E-101 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_21710 af8fbb865877c114a6feec7dcab11c7a 603 SUPERFAMILY SSF56801 17 591 2.22E-97 T 12-10-2018 TL08_21710 af8fbb865877c114a6feec7dcab11c7a 603 Gene3D G3DSA:3.40.50.12780 325 470 1.7E-36 T 12-10-2018 TL08_21710 af8fbb865877c114a6feec7dcab11c7a 603 Pfam PF00501 AMP-binding enzyme 25 472 2.9E-84 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_21710 af8fbb865877c114a6feec7dcab11c7a 603 Gene3D G3DSA:3.40.50.12780 3 320 1.7E-43 T 12-10-2018 TL08_02690 3912f085a865d62f92647786e157ddbc 354 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 70 217 8.3E-31 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TL08_02690 3912f085a865d62f92647786e157ddbc 354 Gene3D G3DSA:3.40.50.970 96 230 5.9E-28 T 12-10-2018 TL08_02690 3912f085a865d62f92647786e157ddbc 354 SUPERFAMILY SSF52518 27 353 2.85E-84 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_14835 f417c5a40d4199ac485d731742093eac 301 Pfam PF01048 Phosphorylase superfamily 2 241 5.1E-27 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TL08_14835 f417c5a40d4199ac485d731742093eac 301 SUPERFAMILY SSF53167 2 244 1.24E-37 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TL08_14835 f417c5a40d4199ac485d731742093eac 301 Gene3D G3DSA:3.40.50.1580 1 258 2.0E-49 T 12-10-2018 TL08_13880 90b5ea5d33de26495a26b0f2c448ef05 205 Pfam PF01872 RibD C-terminal domain 4 189 1.2E-28 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TL08_13880 90b5ea5d33de26495a26b0f2c448ef05 205 SUPERFAMILY SSF53597 4 195 7.2E-26 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_13880 90b5ea5d33de26495a26b0f2c448ef05 205 Gene3D G3DSA:3.40.430.10 1 195 1.9E-42 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_22925 2c6cb1b600444ec04adedbd824e0f4a2 537 Pfam PF01039 Carboxyl transferase domain 50 526 1.5E-151 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TL08_22925 2c6cb1b600444ec04adedbd824e0f4a2 537 Gene3D G3DSA:3.90.226.10 275 537 1.6E-105 T 12-10-2018 TL08_22925 2c6cb1b600444ec04adedbd824e0f4a2 537 SUPERFAMILY SSF52096 27 271 1.24E-67 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_22925 2c6cb1b600444ec04adedbd824e0f4a2 537 SUPERFAMILY SSF52096 239 519 4.3E-90 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_22925 2c6cb1b600444ec04adedbd824e0f4a2 537 Gene3D G3DSA:3.90.226.10 11 273 7.7E-93 T 12-10-2018 TL08_08585 72bd6977bcd13ed1efb679fdc1310583 165 Gene3D G3DSA:3.10.350.10 107 158 3.7E-8 T 12-10-2018 IPR036779 LysM domain superfamily TL08_08585 72bd6977bcd13ed1efb679fdc1310583 165 Pfam PF01476 LysM domain 111 157 3.2E-6 T 12-10-2018 IPR018392 LysM domain TL08_08585 72bd6977bcd13ed1efb679fdc1310583 165 SMART SM00257 108 157 0.0098 T 12-10-2018 IPR018392 LysM domain TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 Pfam PF00067 Cytochrome P450 204 361 5.2E-17 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 Gene3D G3DSA:1.10.630.10 7 391 1.5E-100 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 PRINTS PR00359 B-class P450 signature 188 210 6.4E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 PRINTS PR00359 B-class P450 signature 282 309 6.4E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 PRINTS PR00359 B-class P450 signature 152 167 6.4E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 PRINTS PR00359 B-class P450 signature 310 325 6.4E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 PRINTS PR00359 B-class P450 signature 340 351 6.4E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 PRINTS PR00359 B-class P450 signature 264 275 6.4E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 PRINTS PR00359 B-class P450 signature 135 151 6.4E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 PRINTS PR00359 B-class P450 signature 331 340 6.4E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20000 3a12e4472c6d7f73f3a408a3eb8fefee 391 SUPERFAMILY SSF48264 13 391 2.1E-73 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_02300 bb235cf393b094a3c22dbcba85eff09e 226 Gene3D G3DSA:1.10.10.10 121 226 8.2E-40 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_02300 bb235cf393b094a3c22dbcba85eff09e 226 Gene3D G3DSA:3.40.50.2300 1 120 1.4E-36 T 12-10-2018 TL08_02300 bb235cf393b094a3c22dbcba85eff09e 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 6.3E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_02300 bb235cf393b094a3c22dbcba85eff09e 226 SUPERFAMILY SSF52172 1 125 2.56E-41 T 12-10-2018 IPR011006 CheY-like superfamily TL08_02300 bb235cf393b094a3c22dbcba85eff09e 226 SMART SM00448 2 112 3.3E-44 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_02300 bb235cf393b094a3c22dbcba85eff09e 226 Pfam PF00072 Response regulator receiver domain 4 113 2.0E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_02300 bb235cf393b094a3c22dbcba85eff09e 226 SUPERFAMILY SSF46894 124 225 7.09E-33 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_02300 bb235cf393b094a3c22dbcba85eff09e 226 SMART SM00862 148 224 1.9E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_20570 39a625b0178bd3b8afbd1e56e59de763 230 SUPERFAMILY SSF54909 6 229 6.7E-78 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_20570 39a625b0178bd3b8afbd1e56e59de763 230 Pfam PF06778 Chlorite dismutase 32 220 6.6E-73 T 12-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase TL08_20570 39a625b0178bd3b8afbd1e56e59de763 230 Gene3D G3DSA:3.30.70.1100 126 229 2.8E-35 T 12-10-2018 TL08_16195 676d2c027cddac7955fd3435c720bd00 1313 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 43 379 3.3E-35 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 TL08_16195 676d2c027cddac7955fd3435c720bd00 1313 SUPERFAMILY SSF51998 554 1307 4.44E-99 T 12-10-2018 TL08_16195 676d2c027cddac7955fd3435c720bd00 1313 Pfam PF02901 Pyruvate formate lyase-like 573 1123 4.6E-122 T 12-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 TL08_16195 676d2c027cddac7955fd3435c720bd00 1313 Gene3D G3DSA:3.20.70.20 557 1308 8.2E-189 T 12-10-2018 TL08_16195 676d2c027cddac7955fd3435c720bd00 1313 Pfam PF04261 Dyp-type peroxidase family 141 377 3.6E-18 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 TL08_16195 676d2c027cddac7955fd3435c720bd00 1313 SUPERFAMILY SSF54909 40 379 6.79E-33 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_18035 aabb26176d31afe890912396ccc84447 596 SUPERFAMILY SSF52540 5 532 3.32E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18035 aabb26176d31afe890912396ccc84447 596 Gene3D G3DSA:3.40.50.300 1 229 1.5E-33 T 12-10-2018 TL08_18035 aabb26176d31afe890912396ccc84447 596 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 529 3.0E-14 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TL08_18035 aabb26176d31afe890912396ccc84447 596 SUPERFAMILY SSF52540 2 221 1.55E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18035 aabb26176d31afe890912396ccc84447 596 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 574 1.4E-172 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TL08_18035 aabb26176d31afe890912396ccc84447 596 PIRSF PIRSF003128 1 579 5.7E-153 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TL08_18035 aabb26176d31afe890912396ccc84447 596 Gene3D G3DSA:3.40.50.300 252 575 2.0E-50 T 12-10-2018 TL08_08875 4c26b767b4368b042b11de551124ad78 272 SUPERFAMILY SSF46934 3 56 3.65E-15 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 TL08_08875 4c26b767b4368b042b11de551124ad78 272 Hamap MF_00050 Elongation factor Ts [tsf]. 1 272 63.558 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TL08_08875 4c26b767b4368b042b11de551124ad78 272 SUPERFAMILY SSF54713 58 270 4.5E-40 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TL08_08875 4c26b767b4368b042b11de551124ad78 272 ProSitePatterns PS01127 Elongation factor Ts signature 2. 71 81 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TL08_08875 4c26b767b4368b042b11de551124ad78 272 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 272 1.3E-73 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TL08_08875 4c26b767b4368b042b11de551124ad78 272 Gene3D G3DSA:3.30.479.20 57 143 1.5E-18 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TL08_08875 4c26b767b4368b042b11de551124ad78 272 Pfam PF00889 Elongation factor TS 67 271 2.8E-62 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 TL08_08875 4c26b767b4368b042b11de551124ad78 272 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TL08_08875 4c26b767b4368b042b11de551124ad78 272 Gene3D G3DSA:1.10.286.20 190 236 6.8E-38 T 12-10-2018 TL08_08875 4c26b767b4368b042b11de551124ad78 272 Gene3D G3DSA:1.10.8.10 1 56 1.2E-21 T 12-10-2018 TL08_08875 4c26b767b4368b042b11de551124ad78 272 Gene3D G3DSA:3.30.479.20 160 270 6.8E-38 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TL08_25195 52768304bba5a0a731e39b82a3bd24e8 162 SMART SM00347 46 146 5.4E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_25195 52768304bba5a0a731e39b82a3bd24e8 162 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TL08_25195 52768304bba5a0a731e39b82a3bd24e8 162 SUPERFAMILY SSF46785 25 158 1.95E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_25195 52768304bba5a0a731e39b82a3bd24e8 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 2.6E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_25195 52768304bba5a0a731e39b82a3bd24e8 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 2.6E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_25195 52768304bba5a0a731e39b82a3bd24e8 162 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 2.6E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_25195 52768304bba5a0a731e39b82a3bd24e8 162 Gene3D G3DSA:1.10.10.10 28 161 2.0E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25195 52768304bba5a0a731e39b82a3bd24e8 162 Pfam PF01047 MarR family 54 110 2.3E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00845 a45ba065249fae5d3aeb7ef5ec0ac501 219 Pfam PF04542 Sigma-70 region 2 53 121 1.1E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_00845 a45ba065249fae5d3aeb7ef5ec0ac501 219 Gene3D G3DSA:1.10.1740.10 40 137 7.8E-23 T 12-10-2018 TL08_00845 a45ba065249fae5d3aeb7ef5ec0ac501 219 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 215 5.3E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_00845 a45ba065249fae5d3aeb7ef5ec0ac501 219 SUPERFAMILY SSF88946 43 131 3.66E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_00845 a45ba065249fae5d3aeb7ef5ec0ac501 219 Pfam PF08281 Sigma-70, region 4 159 211 4.2E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_00845 a45ba065249fae5d3aeb7ef5ec0ac501 219 Gene3D G3DSA:1.10.10.10 155 217 2.2E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_00845 a45ba065249fae5d3aeb7ef5ec0ac501 219 SUPERFAMILY SSF88659 156 213 8.07E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_23725 4959a5c87a7adf9c2cf399817b589e01 320 Gene3D G3DSA:3.40.190.10 170 270 6.2E-43 T 12-10-2018 TL08_23725 4959a5c87a7adf9c2cf399817b589e01 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.6E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_23725 4959a5c87a7adf9c2cf399817b589e01 320 Gene3D G3DSA:3.40.190.10 93 279 6.2E-43 T 12-10-2018 TL08_23725 4959a5c87a7adf9c2cf399817b589e01 320 Pfam PF03466 LysR substrate binding domain 90 288 2.1E-37 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_23725 4959a5c87a7adf9c2cf399817b589e01 320 SUPERFAMILY SSF46785 2 110 5.79E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23725 4959a5c87a7adf9c2cf399817b589e01 320 Gene3D G3DSA:1.10.10.10 2 90 3.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23725 4959a5c87a7adf9c2cf399817b589e01 320 SUPERFAMILY SSF53850 92 298 2.64E-32 T 12-10-2018 TL08_17805 5afc55bbb63383ebeb61426bbbb138ca 391 SUPERFAMILY SSF56512 2 357 3.01E-152 T 12-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 TL08_17805 5afc55bbb63383ebeb61426bbbb138ca 391 Gene3D G3DSA:3.90.1230.10 190 296 1.1E-148 T 12-10-2018 TL08_17805 5afc55bbb63383ebeb61426bbbb138ca 391 Pfam PF02898 Nitric oxide synthase, oxygenase domain 2 356 9.6E-151 T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 TL08_17805 5afc55bbb63383ebeb61426bbbb138ca 391 PIRSF PIRSF037219 1 364 3.8E-154 T 12-10-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.14.47|KEGG: 00330+1.14.14.47 TL08_17805 5afc55bbb63383ebeb61426bbbb138ca 391 Gene3D G3DSA:3.90.440.10 76 189 1.1E-148 T 12-10-2018 TL08_17805 5afc55bbb63383ebeb61426bbbb138ca 391 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 59 66 - T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 TL08_17805 5afc55bbb63383ebeb61426bbbb138ca 391 Gene3D G3DSA:3.90.340.10 2 351 1.1E-148 T 12-10-2018 TL08_02050 89b9a5ce25758bdfca0d74334b9a3108 571 Gene3D G3DSA:3.20.20.540 151 465 7.0E-150 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TL08_02050 89b9a5ce25758bdfca0d74334b9a3108 571 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 109 532 8.2E-207 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TL08_02050 89b9a5ce25758bdfca0d74334b9a3108 571 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 108 534 95.429 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TL08_02050 89b9a5ce25758bdfca0d74334b9a3108 571 Pfam PF01964 Radical SAM ThiC family 109 529 2.5E-198 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TL08_02050 89b9a5ce25758bdfca0d74334b9a3108 571 Pfam PF13667 ThiC-associated domain 36 99 2.8E-15 T 12-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TL08_04890 c58450313b1beb435cd18374061d8e51 123 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 100 110 - T 12-10-2018 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 TL08_04890 c58450313b1beb435cd18374061d8e51 123 Pfam PF02467 Transcription factor WhiB 42 90 1.3E-15 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TL08_04890 c58450313b1beb435cd18374061d8e51 123 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 26 104 16.262 T 12-10-2018 IPR003482 Transcription factor WhiB TL08_18360 e9085994e5ee023d18caee4d234b4a37 362 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 109 2.5E-23 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_18360 e9085994e5ee023d18caee4d234b4a37 362 SUPERFAMILY SSF51735 1 151 1.2E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_18360 e9085994e5ee023d18caee4d234b4a37 362 SUPERFAMILY SSF55347 127 273 5.56E-26 T 12-10-2018 TL08_18360 e9085994e5ee023d18caee4d234b4a37 362 Gene3D G3DSA:3.30.360.10 122 329 3.1E-89 T 12-10-2018 TL08_18360 e9085994e5ee023d18caee4d234b4a37 362 Gene3D G3DSA:3.40.50.720 1 306 3.1E-89 T 12-10-2018 TL08_18360 e9085994e5ee023d18caee4d234b4a37 362 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 129 236 5.1E-11 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 192 208 - T 12-10-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 Gene3D G3DSA:3.20.20.40 127 414 1.0E-85 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 PRINTS PR00733 Glycosyl hydrolase family 6 signature 187 200 3.8E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 PRINTS PR00733 Glycosyl hydrolase family 6 signature 148 167 3.8E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 PRINTS PR00733 Glycosyl hydrolase family 6 signature 302 312 3.8E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 PRINTS PR00733 Glycosyl hydrolase family 6 signature 351 371 3.8E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 PRINTS PR00733 Glycosyl hydrolase family 6 signature 337 350 3.8E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 PRINTS PR00733 Glycosyl hydrolase family 6 signature 376 390 3.8E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 PRINTS PR00733 Glycosyl hydrolase family 6 signature 272 285 3.8E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 SUPERFAMILY SSF51989 126 412 1.96E-69 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 Pfam PF01341 Glycosyl hydrolases family 6 150 396 6.7E-63 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_25625 f3dfac6ad1e7c257a127978143452c39 415 PIRSF PIRSF001100 66 414 1.4E-76 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_07500 0af1eece8b2c6afaace13d90f60975c1 592 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 53 591 2.0E-197 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TL08_07500 0af1eece8b2c6afaace13d90f60975c1 592 SUPERFAMILY SSF51703 31 586 1.33E-185 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TL08_07500 0af1eece8b2c6afaace13d90f60975c1 592 Gene3D G3DSA:3.20.20.240 15 592 1.8E-220 T 12-10-2018 TL08_07500 0af1eece8b2c6afaace13d90f60975c1 592 Pfam PF01642 Methylmalonyl-CoA mutase 54 584 5.0E-209 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.6E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.1E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 3.1E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.1E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 3.1E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.1E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 SUPERFAMILY SSF51735 7 235 4.78E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 Gene3D G3DSA:3.40.50.720 3 240 4.0E-68 T 12-10-2018 TL08_21605 82c75a05353994cb95d96bd8dc7b7078 241 Pfam PF00106 short chain dehydrogenase 8 204 3.2E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17755 37e50a70010ccbad5905bc7b992ae60d 255 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 1.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_17755 37e50a70010ccbad5905bc7b992ae60d 255 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 1.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_17755 37e50a70010ccbad5905bc7b992ae60d 255 SUPERFAMILY SSF48498 98 212 2.62E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_17755 37e50a70010ccbad5905bc7b992ae60d 255 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 1.1E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_17755 37e50a70010ccbad5905bc7b992ae60d 255 Gene3D G3DSA:1.10.10.60 17 66 3.0E-21 T 12-10-2018 TL08_17755 37e50a70010ccbad5905bc7b992ae60d 255 Gene3D G3DSA:1.10.357.10 67 212 6.5E-29 T 12-10-2018 TL08_17755 37e50a70010ccbad5905bc7b992ae60d 255 SUPERFAMILY SSF46689 17 101 2.59E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Gene3D G3DSA:3.30.70.270 623 794 3.1E-46 T 12-10-2018 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SUPERFAMILY SSF55785 142 242 2.09E-11 T 12-10-2018 IPR035965 PAS domain superfamily TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Gene3D G3DSA:3.20.20.450 795 1044 1.2E-83 T 12-10-2018 IPR035919 EAL domain superfamily TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Pfam PF00990 Diguanylate cyclase, GGDEF domain 623 777 1.1E-33 T 12-10-2018 IPR000160 GGDEF domain TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SMART SM00052 792 1037 5.1E-87 T 12-10-2018 IPR001633 EAL domain TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Pfam PF08448 PAS fold 507 614 5.9E-17 T 12-10-2018 IPR013656 PAS fold-4 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SMART SM00086 318 359 2.9 T 12-10-2018 IPR001610 PAC motif TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SMART SM00086 571 612 7.3 T 12-10-2018 IPR001610 PAC motif TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SMART SM00086 198 240 3.0E-4 T 12-10-2018 IPR001610 PAC motif TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SMART SM00086 444 485 6.8 T 12-10-2018 IPR001610 PAC motif TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Gene3D G3DSA:3.30.450.20 242 357 1.9E-7 T 12-10-2018 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SUPERFAMILY SSF141868 797 1042 1.16E-76 T 12-10-2018 IPR035919 EAL domain superfamily TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Gene3D G3DSA:2.10.70.100 440 486 1.1E-7 T 12-10-2018 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Gene3D G3DSA:2.10.70.100 195 241 2.5E-7 T 12-10-2018 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Pfam PF08447 PAS fold 149 234 2.5E-9 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Pfam PF08447 PAS fold 394 478 2.8E-12 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SUPERFAMILY SSF55073 628 781 3.49E-37 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SMART SM00267 612 782 2.0E-50 T 12-10-2018 IPR000160 GGDEF domain TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Gene3D G3DSA:3.30.450.20 495 622 3.3E-22 T 12-10-2018 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 619 781 8.5E-33 T 12-10-2018 IPR000160 GGDEF domain TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Gene3D G3DSA:3.30.450.20 368 437 3.4E-16 T 12-10-2018 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Gene3D G3DSA:3.30.450.20 122 189 4.3E-11 T 12-10-2018 TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SMART SM00091 497 563 1.8E-10 T 12-10-2018 IPR000014 PAS domain TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SMART SM00091 368 438 7.8 T 12-10-2018 IPR000014 PAS domain TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SMART SM00091 17 83 270.0 T 12-10-2018 IPR000014 PAS domain TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SUPERFAMILY SSF55785 356 483 1.92E-18 T 12-10-2018 IPR035965 PAS domain superfamily TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SUPERFAMILY SSF55785 483 610 8.54E-22 T 12-10-2018 IPR035965 PAS domain superfamily TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 Pfam PF00563 EAL domain 798 1032 7.9E-64 T 12-10-2018 IPR001633 EAL domain TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 494 619 4.7E-22 T 12-10-2018 IPR000014 PAS domain TL08_23130 086177a5a6aeb35ae988b353f2223f84 1053 SUPERFAMILY SSF55785 287 367 1.29E-5 T 12-10-2018 IPR035965 PAS domain superfamily TL08_27000 87e4d174d5a219d2e4db5183287bb105 252 SUPERFAMILY SSF48498 91 234 1.51E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_27000 87e4d174d5a219d2e4db5183287bb105 252 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_27000 87e4d174d5a219d2e4db5183287bb105 252 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 4.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_27000 87e4d174d5a219d2e4db5183287bb105 252 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 4.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_27000 87e4d174d5a219d2e4db5183287bb105 252 Gene3D G3DSA:1.10.357.10 1 243 4.4E-61 T 12-10-2018 TL08_27000 87e4d174d5a219d2e4db5183287bb105 252 SUPERFAMILY SSF46689 6 80 1.15E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_15180 85ccfed30cb2beb049529172ad86fbff 361 Gene3D G3DSA:3.40.50.2300 179 317 6.3E-83 T 12-10-2018 TL08_15180 85ccfed30cb2beb049529172ad86fbff 361 Gene3D G3DSA:3.40.50.2300 76 334 6.3E-83 T 12-10-2018 TL08_15180 85ccfed30cb2beb049529172ad86fbff 361 SUPERFAMILY SSF53822 72 343 2.04E-69 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_15180 85ccfed30cb2beb049529172ad86fbff 361 Pfam PF13407 Periplasmic binding protein domain 75 335 7.9E-53 T 12-10-2018 IPR025997 Periplasmic binding protein TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.40.50.720 4186 4731 4.3E-163 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.40.50.720 948 1476 1.1E-95 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.40.50.720 2512 3103 1.8E-156 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF52151 2138 2429 3.14E-64 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4792 4807 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF55048 711 772 1.44E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF00550 Phosphopantetheine attachment site 3140 3205 3.8E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF00550 Phosphopantetheine attachment site 4767 4833 4.4E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF00550 Phosphopantetheine attachment site 1508 1573 2.6E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM01294 4766 4833 2.7E-5 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM01294 3139 3206 4.4E-7 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM01294 1506 1573 1.3E-4 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3393 3409 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.40.47.10 16 455 1.6E-183 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.40.47.10 3218 3659 4.1E-181 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF55048 2265 2333 2.62E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF51735 2849 3083 7.26E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 189 205 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.30.70.3290 2052 2491 3.4E-154 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF00698 Acyl transferase domain 3780 4139 1.9E-54 T 12-10-2018 IPR014043 Acyl transferase TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF00698 Acyl transferase domain 2139 2461 9.7E-80 T 12-10-2018 IPR014043 Acyl transferase TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF00698 Acyl transferase domain 562 904 4.3E-56 T 12-10-2018 IPR014043 Acyl transferase TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00823 Phosphopantetheine attachment site 4765 4837 7.4E-28 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00823 Phosphopantetheine attachment site 3138 3210 1.4E-32 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00823 Phosphopantetheine attachment site 1505 1577 1.3E-26 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2141 2443 7.4E-109 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3780 4121 2.5E-112 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 562 887 2.7E-114 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF51735 4235 4465 3.66E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.40.47.10 1591 2043 6.9E-194 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF08990 Erythronolide synthase docking 2 27 2.5E-11 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.40.366.10 3778 4124 4.8E-149 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.40.366.10 560 890 5.5E-157 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.40.366.10 2139 2446 3.4E-154 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3608 3742 2.2E-11 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1977 2103 3.4E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 404 524 8.6E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.30.70.3290 474 933 5.5E-157 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:1.10.1200.10 1487 1579 7.5E-31 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:1.10.1200.10 4747 4840 2.1E-32 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:1.10.1200.10 3120 3212 1.9E-34 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF47336 1499 1614 1.83E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF52151 3776 4090 4.19E-70 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF52151 558 871 8.63E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF55048 3922 3993 4.58E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4480 4659 4.0E-48 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2853 3032 5.8E-54 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF53901 3228 3603 5.29E-100 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1762 1778 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF51735 2561 2813 2.79E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3165 3180 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF53901 1596 1970 1.19E-105 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 284 401 2.2E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3488 3605 2.5E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1857 1974 5.7E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF51735 4476 4724 2.15E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00825 Beta-ketoacyl synthase 3234 3658 1.9E-208 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00825 Beta-ketoacyl synthase 1601 2027 4.7E-227 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SMART SM00825 Beta-ketoacyl synthase 36 454 2.6E-213 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF47336 4757 4843 2.88E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF51735 1223 1463 1.14E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Gene3D G3DSA:3.30.70.3290 3693 4167 4.8E-149 T 12-10-2018 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF47336 3132 3246 9.29E-23 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF53901 31 399 3.27E-97 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF08659 KR domain 4480 4658 1.5E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF08659 KR domain 2853 3031 4.7E-60 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF08659 KR domain 1238 1401 1.2E-9 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1599 1849 4.6E-91 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3232 3480 3.1E-82 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 276 7.7E-84 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1532 1547 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15885 c7ca0cb704cc6eb22fa4d68009ce415c 4918 SUPERFAMILY SSF51735 999 1211 3.94E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_04340 77358cd424e2320106093d92a979ee3e 651 Pfam PF02687 FtsX-like permease family 551 637 4.6E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TL08_04340 77358cd424e2320106093d92a979ee3e 651 Pfam PF02687 FtsX-like permease family 89 178 2.2E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TL08_17360 b7f203addd86980d5cd9c0790a370e74 715 Pfam PF00931 NB-ARC domain 73 305 3.1E-8 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_17360 b7f203addd86980d5cd9c0790a370e74 715 SUPERFAMILY SSF48452 506 694 2.28E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17360 b7f203addd86980d5cd9c0790a370e74 715 SUPERFAMILY SSF52540 57 310 3.96E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17360 b7f203addd86980d5cd9c0790a370e74 715 Gene3D G3DSA:1.25.40.10 461 712 3.3E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17360 b7f203addd86980d5cd9c0790a370e74 715 Gene3D G3DSA:3.40.50.300 45 210 1.7E-21 T 12-10-2018 TL08_17360 b7f203addd86980d5cd9c0790a370e74 715 PRINTS PR00364 Disease resistance protein signature 83 98 1.1E-10 T 12-10-2018 TL08_17360 b7f203addd86980d5cd9c0790a370e74 715 PRINTS PR00364 Disease resistance protein signature 161 175 1.1E-10 T 12-10-2018 TL08_17360 b7f203addd86980d5cd9c0790a370e74 715 PRINTS PR00364 Disease resistance protein signature 249 263 1.1E-10 T 12-10-2018 TL08_13055 71cf7fe1de06f36a2ea26c7f245ed26d 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 3.4E-6 T 12-10-2018 TL08_13055 71cf7fe1de06f36a2ea26c7f245ed26d 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 372 391 3.4E-6 T 12-10-2018 TL08_13055 71cf7fe1de06f36a2ea26c7f245ed26d 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 3.4E-6 T 12-10-2018 TL08_13055 71cf7fe1de06f36a2ea26c7f245ed26d 529 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 3.4E-6 T 12-10-2018 TL08_13055 71cf7fe1de06f36a2ea26c7f245ed26d 529 Pfam PF07690 Major Facilitator Superfamily 21 418 5.6E-51 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_13055 71cf7fe1de06f36a2ea26c7f245ed26d 529 SUPERFAMILY SSF103473 7 521 6.8E-59 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_13055 71cf7fe1de06f36a2ea26c7f245ed26d 529 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 426 1.6E-71 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TL08_13055 71cf7fe1de06f36a2ea26c7f245ed26d 529 Gene3D G3DSA:1.20.1720.10 18 221 9.6E-43 T 12-10-2018 TL08_12640 d6d34fc5312c937b237f954e6262343d 400 SUPERFAMILY SSF50129 40 224 3.65E-49 T 12-10-2018 IPR011032 GroES-like superfamily TL08_12640 d6d34fc5312c937b237f954e6262343d 400 Gene3D G3DSA:3.40.50.720 205 341 2.1E-105 T 12-10-2018 TL08_12640 d6d34fc5312c937b237f954e6262343d 400 SUPERFAMILY SSF51735 190 362 4.68E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_12640 d6d34fc5312c937b237f954e6262343d 400 Pfam PF00107 Zinc-binding dehydrogenase 228 351 1.2E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_12640 d6d34fc5312c937b237f954e6262343d 400 SMART SM00829 40 396 1.4E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_12640 d6d34fc5312c937b237f954e6262343d 400 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 99 113 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_12640 d6d34fc5312c937b237f954e6262343d 400 Gene3D G3DSA:3.90.180.10 50 395 2.1E-105 T 12-10-2018 TL08_12640 d6d34fc5312c937b237f954e6262343d 400 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 66 186 1.6E-24 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 SUPERFAMILY SSF47413 12 70 6.7E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 Gene3D G3DSA:3.40.50.300 113 278 1.8E-28 T 12-10-2018 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 PRINTS PR00364 Disease resistance protein signature 316 330 5.2E-12 T 12-10-2018 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 PRINTS PR00364 Disease resistance protein signature 231 245 5.2E-12 T 12-10-2018 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 PRINTS PR00364 Disease resistance protein signature 154 169 5.2E-12 T 12-10-2018 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 SUPERFAMILY SSF48452 587 775 1.57E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 SMART SM00530 18 74 1.7E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 SUPERFAMILY SSF52540 115 383 2.72E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 Gene3D G3DSA:1.10.260.40 13 76 3.1E-11 T 12-10-2018 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 Pfam PF13560 Helix-turn-helix domain 15 75 7.5E-10 T 12-10-2018 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 Pfam PF00931 NB-ARC domain 150 387 1.3E-14 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 Gene3D G3DSA:1.25.40.10 683 818 5.2E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 Gene3D G3DSA:1.25.40.10 542 682 4.5E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_17590 3e745eb58b206325e721efff3bb4ba23 825 Pfam PF13424 Tetratricopeptide repeat 657 719 9.2E-8 T 12-10-2018 TL08_07195 797752ada97c2023120e3350c6391f8e 137 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 36.39 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 TL08_07195 797752ada97c2023120e3350c6391f8e 137 Pfam PF06339 Ectoine synthase 1 125 2.6E-55 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 TL08_07195 797752ada97c2023120e3350c6391f8e 137 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 2.0E-35 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 TL08_07195 797752ada97c2023120e3350c6391f8e 137 Gene3D G3DSA:2.60.120.10 1 115 3.2E-41 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_07195 797752ada97c2023120e3350c6391f8e 137 SUPERFAMILY SSF51182 8 125 1.45E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_01570 1c944fcdfb0b8d20585fec0218f46aae 156 SUPERFAMILY SSF55811 8 150 7.85E-31 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_01570 1c944fcdfb0b8d20585fec0218f46aae 156 Gene3D G3DSA:3.90.79.10 4 153 9.6E-32 T 12-10-2018 TL08_01570 1c944fcdfb0b8d20585fec0218f46aae 156 Pfam PF00293 NUDIX domain 20 130 4.9E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_01570 1c944fcdfb0b8d20585fec0218f46aae 156 PRINTS PR00502 NUDIX hydrolase family signature 44 58 3.4E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_01570 1c944fcdfb0b8d20585fec0218f46aae 156 PRINTS PR00502 NUDIX hydrolase family signature 58 73 3.4E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_01570 1c944fcdfb0b8d20585fec0218f46aae 156 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_02935 accfa9bbd3a46f3c2c72dda23011bdbe 392 Pfam PF07730 Histidine kinase 198 263 2.1E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_02935 accfa9bbd3a46f3c2c72dda23011bdbe 392 Gene3D G3DSA:3.30.565.10 264 385 4.1E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_02935 accfa9bbd3a46f3c2c72dda23011bdbe 392 SUPERFAMILY SSF55874 271 376 9.7E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_02935 accfa9bbd3a46f3c2c72dda23011bdbe 392 SMART SM00387 295 385 1.5E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_18210 4b14d395a518a5d1b378f2d2f7e727b0 265 Gene3D G3DSA:1.20.120.450 25 178 3.9E-47 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_18210 4b14d395a518a5d1b378f2d2f7e727b0 265 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 42 248 5.8E-31 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type TL08_18210 4b14d395a518a5d1b378f2d2f7e727b0 265 SUPERFAMILY SSF109854 31 178 2.75E-39 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_18210 4b14d395a518a5d1b378f2d2f7e727b0 265 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 38 172 1.3E-25 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 TL08_18210 4b14d395a518a5d1b378f2d2f7e727b0 265 SUPERFAMILY SSF55718 182 264 5.65E-9 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 971 1186 1.2E-30 T 12-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Gene3D G3DSA:3.10.196.10 909 1186 4.0E-45 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 SMART SM01018 638 720 1.9E-39 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Gene3D G3DSA:1.10.1240.10 630 717 3.1E-28 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Gene3D G3DSA:3.20.20.20 329 625 3.0E-97 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 PIRSF PIRSF000381 3 1187 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Gene3D G3DSA:3.40.50.280 722 877 2.2E-39 T 12-10-2018 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Pfam PF02607 B12 binding domain 642 713 2.7E-22 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 SUPERFAMILY SSF51717 340 611 1.96E-76 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 SUPERFAMILY SSF82282 7 382 1.1E-105 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Pfam PF00809 Pterin binding enzyme 344 579 6.1E-47 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Gene3D G3DSA:1.10.288.10 925 985 4.0E-45 T 12-10-2018 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 TIGRFAM TIGR02082 metH: methionine synthase 14 1186 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Pfam PF02574 Homocysteine S-methyltransferase 18 308 2.5E-62 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 SUPERFAMILY SSF52242 720 857 4.06E-36 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 SUPERFAMILY SSF47644 636 719 3.4E-23 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Gene3D G3DSA:3.20.20.330 4 320 9.4E-93 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 Pfam PF02310 B12 binding domain 726 843 2.9E-18 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TL08_13210 4629d099ec7fcba335d766a4cc9a2bea 1187 SUPERFAMILY SSF56507 900 1187 4.84E-84 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_09465 f839f797299370691a0daa0aebd42f71 500 Gene3D G3DSA:3.40.1190.10 107 339 3.1E-68 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_09465 f839f797299370691a0daa0aebd42f71 500 SUPERFAMILY SSF63418 2 81 7.19E-19 T 12-10-2018 IPR035911 MurE/MurF, N-terminal TL08_09465 f839f797299370691a0daa0aebd42f71 500 Pfam PF01225 Mur ligase family, catalytic domain 30 74 1.9E-8 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TL08_09465 f839f797299370691a0daa0aebd42f71 500 Pfam PF02875 Mur ligase family, glutamate ligase domain 345 432 1.1E-21 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TL08_09465 f839f797299370691a0daa0aebd42f71 500 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 487 5.4E-121 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_09465 f839f797299370691a0daa0aebd42f71 500 Gene3D G3DSA:3.40.1390.10 1 81 1.7E-24 T 12-10-2018 TL08_09465 f839f797299370691a0daa0aebd42f71 500 Pfam PF08245 Mur ligase middle domain 132 322 2.8E-41 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TL08_09465 f839f797299370691a0daa0aebd42f71 500 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 489 31.206 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_09465 f839f797299370691a0daa0aebd42f71 500 Gene3D G3DSA:3.90.190.20 342 496 8.0E-35 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_09465 f839f797299370691a0daa0aebd42f71 500 SUPERFAMILY SSF53623 127 338 2.49E-51 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_09465 f839f797299370691a0daa0aebd42f71 500 SUPERFAMILY SSF53244 345 487 7.33E-32 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_09790 c76e2c2ce5f5a39876413874d03c9959 271 Gene3D G3DSA:3.20.20.70 1 268 4.9E-86 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_09790 c76e2c2ce5f5a39876413874d03c9959 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TL08_09790 c76e2c2ce5f5a39876413874d03c9959 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 262 31.063 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TL08_09790 c76e2c2ce5f5a39876413874d03c9959 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 257 2.1E-61 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TL08_09790 c76e2c2ce5f5a39876413874d03c9959 271 SUPERFAMILY SSF51366 1 239 2.92E-75 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TL08_09790 c76e2c2ce5f5a39876413874d03c9959 271 Pfam PF00290 Tryptophan synthase alpha chain 8 257 3.3E-67 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 9.3E-23 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 SUPERFAMILY SSF64288 67 260 3.93E-36 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 Gene3D G3DSA:3.40.1410.10 92 257 2.4E-41 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 SMART SM00866 112 254 1.5E-27 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 SUPERFAMILY SSF46785 16 92 4.92E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 Pfam PF07702 UTRA domain 113 252 4.5E-27 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 6.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 6.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 SMART SM00345 20 79 5.2E-23 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22470 910f2ef3e37d49b6d90fec9380ac80d5 263 Gene3D G3DSA:1.10.10.10 18 91 4.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_00255 62cfad91c5f1736a42de91b4d58991cf 215 Gene3D G3DSA:1.10.3720.10 14 206 2.3E-24 T 12-10-2018 IPR035906 MetI-like superfamily TL08_00255 62cfad91c5f1736a42de91b4d58991cf 215 SUPERFAMILY SSF161098 13 198 9.94E-30 T 12-10-2018 IPR035906 MetI-like superfamily TL08_00255 62cfad91c5f1736a42de91b4d58991cf 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 205 1.8E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 SUPERFAMILY SSF48264 38 397 6.42E-89 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 Pfam PF00067 Cytochrome P450 190 371 1.6E-21 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 Gene3D G3DSA:1.10.630.10 9 397 1.8E-112 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00359 B-class P450 signature 337 346 7.8E-44 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00359 B-class P450 signature 346 357 7.8E-44 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00359 B-class P450 signature 287 314 7.8E-44 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00359 B-class P450 signature 90 101 7.8E-44 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00359 B-class P450 signature 270 281 7.8E-44 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00359 B-class P450 signature 191 213 7.8E-44 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00359 B-class P450 signature 154 169 7.8E-44 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00359 B-class P450 signature 137 153 7.8E-44 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00385 P450 superfamily signature 235 252 2.2E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00385 P450 superfamily signature 270 281 2.2E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00385 P450 superfamily signature 346 357 2.2E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18515 bcf0ae74a9dc7b7027b47d9341f62de0 397 PRINTS PR00385 P450 superfamily signature 337 346 2.2E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15045 83604a2f5022c94381126b22326ecedd 548 Gene3D G3DSA:3.40.50.1820 45 548 4.2E-139 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15045 83604a2f5022c94381126b22326ecedd 548 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 215 230 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site TL08_15045 83604a2f5022c94381126b22326ecedd 548 Pfam PF00135 Carboxylesterase family 50 521 3.9E-108 T 12-10-2018 IPR002018 Carboxylesterase, type B TL08_15045 83604a2f5022c94381126b22326ecedd 548 SUPERFAMILY SSF53474 50 546 1.82E-112 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10375 aeec3367347098fd781069e2e10a0f9d 310 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 20 310 53.392 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_10375 aeec3367347098fd781069e2e10a0f9d 310 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 25 310 9.4E-146 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_10375 aeec3367347098fd781069e2e10a0f9d 310 SUPERFAMILY SSF51366 34 280 4.14E-63 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TL08_10375 aeec3367347098fd781069e2e10a0f9d 310 Pfam PF01680 SOR/SNZ family 23 228 4.0E-107 T 12-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_10375 aeec3367347098fd781069e2e10a0f9d 310 PIRSF PIRSF029271 12 310 4.5E-151 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_10375 aeec3367347098fd781069e2e10a0f9d 310 Gene3D G3DSA:3.20.20.70 18 310 3.5E-151 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_10375 aeec3367347098fd781069e2e10a0f9d 310 ProSitePatterns PS01235 PdxS/SNZ family signature. 221 239 - T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_12815 9f06d2bfe16ad3d8c3cf567a166b63c8 198 SUPERFAMILY SSF52540 16 188 3.34E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12815 9f06d2bfe16ad3d8c3cf567a166b63c8 198 Gene3D G3DSA:3.40.50.300 7 193 1.8E-15 T 12-10-2018 TL08_12815 9f06d2bfe16ad3d8c3cf567a166b63c8 198 Pfam PF03029 Conserved hypothetical ATP binding protein 21 184 1.5E-24 T 12-10-2018 IPR004130 GPN-loop GTPase TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 Gene3D G3DSA:3.40.50.620 1 157 1.9E-54 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 SUPERFAMILY SSF52374 1 153 5.9E-44 T 12-10-2018 TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 Pfam PF01467 Cytidylyltransferase-like 5 132 4.3E-19 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 154 1.4E-60 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 58 5.8E-18 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.6E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.6E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.6E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 1.6E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.6E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TL08_22410 d343577bb809fa0eba6fa209a50c90e0 162 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 34.211 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TL08_14355 0c55f903c9d3edca810c3bd784ab501e 765 Pfam PF00271 Helicase conserved C-terminal domain 310 410 4.0E-17 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_14355 0c55f903c9d3edca810c3bd784ab501e 765 Gene3D G3DSA:3.40.50.300 11 215 5.9E-49 T 12-10-2018 TL08_14355 0c55f903c9d3edca810c3bd784ab501e 765 Gene3D G3DSA:3.40.50.300 300 436 8.8E-26 T 12-10-2018 TL08_14355 0c55f903c9d3edca810c3bd784ab501e 765 SMART SM00487 25 228 1.1E-37 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_14355 0c55f903c9d3edca810c3bd784ab501e 765 Pfam PF00270 DEAD/DEAH box helicase 31 199 6.3E-28 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_14355 0c55f903c9d3edca810c3bd784ab501e 765 SUPERFAMILY SSF52540 38 415 7.72E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14355 0c55f903c9d3edca810c3bd784ab501e 765 SMART SM00490 331 412 8.2E-21 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_04200 7cb153f6bc8c2520cd72c62341ccd830 433 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 24 424 23.119 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TL08_04200 7cb153f6bc8c2520cd72c62341ccd830 433 Pfam PF13742 OB-fold nucleic acid binding domain 31 125 3.0E-15 T 12-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 TL08_04200 7cb153f6bc8c2520cd72c62341ccd830 433 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 32 423 6.3E-109 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TL08_04200 7cb153f6bc8c2520cd72c62341ccd830 433 Pfam PF02601 Exonuclease VII, large subunit 148 351 2.3E-56 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 TL08_06005 f4798cabc538cbdf458ff923d3731c3f 214 Pfam PF12464 Maltose acetyltransferase 38 88 1.1E-9 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 TL08_06005 f4798cabc538cbdf458ff923d3731c3f 214 Gene3D G3DSA:2.160.10.10 33 214 1.4E-59 T 12-10-2018 TL08_06005 f4798cabc538cbdf458ff923d3731c3f 214 SUPERFAMILY SSF51161 38 213 3.6E-46 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TL08_06005 f4798cabc538cbdf458ff923d3731c3f 214 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 161 195 7.2E-10 T 12-10-2018 IPR001451 Hexapeptide repeat TL08_06005 f4798cabc538cbdf458ff923d3731c3f 214 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 169 197 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TL08_06005 f4798cabc538cbdf458ff923d3731c3f 214 SMART SM01266 36 89 8.0E-13 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 TL08_02985 dc906634e3658a089a3c885f00ce8ee0 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 6 212 39.566 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02985 dc906634e3658a089a3c885f00ce8ee0 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site TL08_02985 dc906634e3658a089a3c885f00ce8ee0 216 Gene3D G3DSA:2.40.50.620 37 101 3.4E-17 T 12-10-2018 TL08_02985 dc906634e3658a089a3c885f00ce8ee0 216 SUPERFAMILY SSF50447 5 213 9.71E-82 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_02985 dc906634e3658a089a3c885f00ce8ee0 216 Pfam PF00297 Ribosomal protein L3 99 186 3.5E-17 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02985 dc906634e3658a089a3c885f00ce8ee0 216 Gene3D G3DSA:2.40.30.10 127 215 2.1E-16 T 12-10-2018 TL08_02985 dc906634e3658a089a3c885f00ce8ee0 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 8 209 2.3E-88 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08370 48867b301b3563dc41ff7e77b04af6d7 387 Pfam PF00480 ROK family 85 379 3.0E-48 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_08370 48867b301b3563dc41ff7e77b04af6d7 387 Gene3D G3DSA:1.10.10.10 3 76 4.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08370 48867b301b3563dc41ff7e77b04af6d7 387 Gene3D G3DSA:3.30.420.40 204 366 7.0E-69 T 12-10-2018 TL08_08370 48867b301b3563dc41ff7e77b04af6d7 387 Gene3D G3DSA:3.30.420.40 92 376 7.0E-69 T 12-10-2018 TL08_08370 48867b301b3563dc41ff7e77b04af6d7 387 SUPERFAMILY SSF53067 84 382 5.94E-41 T 12-10-2018 TL08_08370 48867b301b3563dc41ff7e77b04af6d7 387 SUPERFAMILY SSF46785 10 74 1.33E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 Gene3D G3DSA:3.50.50.60 7 369 2.6E-105 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 342 360 7.7E-39 T 12-10-2018 TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 175 190 7.7E-39 T 12-10-2018 TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 324 7.7E-39 T 12-10-2018 TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 324 340 7.7E-39 T 12-10-2018 TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 360 376 7.7E-39 T 12-10-2018 TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 7.7E-39 T 12-10-2018 TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 Pfam PF01494 FAD binding domain 5 374 1.7E-98 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 Gene3D G3DSA:3.40.30.120 432 590 5.7E-51 T 12-10-2018 TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 SUPERFAMILY SSF51905 6 386 1.26E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_18505 15b08aef4eb4f4ea633eec6967d2a675 597 Gene3D G3DSA:3.30.9.50 72 306 2.6E-105 T 12-10-2018 TL08_01960 4d992168c41c4fe06be1c6038ab774b5 379 SMART SM00354 23 94 6.6E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_01960 4d992168c41c4fe06be1c6038ab774b5 379 Gene3D G3DSA:1.10.260.40 15 77 8.2E-17 T 12-10-2018 TL08_01960 4d992168c41c4fe06be1c6038ab774b5 379 Pfam PF13377 Periplasmic binding protein-like domain 191 366 1.4E-28 T 12-10-2018 TL08_01960 4d992168c41c4fe06be1c6038ab774b5 379 SUPERFAMILY SSF53822 96 360 1.92E-45 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_01960 4d992168c41c4fe06be1c6038ab774b5 379 Pfam PF00356 Bacterial regulatory proteins, lacI family 26 67 4.7E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_01960 4d992168c41c4fe06be1c6038ab774b5 379 SUPERFAMILY SSF47413 23 81 4.22E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_01960 4d992168c41c4fe06be1c6038ab774b5 379 Gene3D G3DSA:3.40.50.2300 78 343 1.9E-57 T 12-10-2018 TL08_01960 4d992168c41c4fe06be1c6038ab774b5 379 Gene3D G3DSA:3.40.50.2300 183 328 1.9E-57 T 12-10-2018 TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 SUPERFAMILY SSF54909 64 138 7.11E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 Pfam PF01037 Lrp/AsnC ligand binding domain 84 134 2.4E-9 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 9.8E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 9.8E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 9.8E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 SMART SM00344 3 110 3.3E-27 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 Gene3D G3DSA:1.10.10.10 1 54 1.1E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 SUPERFAMILY SSF46785 2 62 5.4E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 Gene3D G3DSA:3.30.70.920 55 138 2.6E-16 T 12-10-2018 TL08_25745 cff1f9dab83fd816d1fe5f34f2a51c7a 153 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 8.4E-19 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_11885 7a3884b209840b42cc51d4528350b1f7 232 Gene3D G3DSA:3.30.420.60 95 208 1.3E-12 T 12-10-2018 TL08_11885 7a3884b209840b42cc51d4528350b1f7 232 SUPERFAMILY SSF53137 94 222 5.89E-20 T 12-10-2018 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 Pfam PF02803 Thiolase, C-terminal domain 274 393 6.6E-41 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 Pfam PF00108 Thiolase, N-terminal domain 7 265 1.5E-77 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 Gene3D G3DSA:3.40.47.10 141 392 1.1E-146 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 SUPERFAMILY SSF53901 274 393 8.64E-38 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 Gene3D G3DSA:3.40.47.10 8 278 1.1E-146 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 3.8E-135 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 PIRSF PIRSF000429 1 396 3.8E-131 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TL08_12630 338ecd4c5a2f0a95eabfd4ce7da4896f 399 SUPERFAMILY SSF53901 5 271 6.88E-78 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_21535 2c3ad0cc64a6d0f3bf58f21660d2bd03 189 Pfam PF13508 Acetyltransferase (GNAT) domain 103 164 6.2E-7 T 12-10-2018 IPR000182 GNAT domain TL08_21535 2c3ad0cc64a6d0f3bf58f21660d2bd03 189 Gene3D G3DSA:3.40.630.30 11 186 7.9E-15 T 12-10-2018 TL08_21535 2c3ad0cc64a6d0f3bf58f21660d2bd03 189 SUPERFAMILY SSF55729 33 179 1.05E-14 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_17215 1d81e5b5cdf3764f4fdb14a25d25a099 121 Pfam PF01022 Bacterial regulatory protein, arsR family 39 86 4.5E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_17215 1d81e5b5cdf3764f4fdb14a25d25a099 121 SUPERFAMILY SSF46785 16 111 1.06E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17215 1d81e5b5cdf3764f4fdb14a25d25a099 121 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 12-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 TL08_17215 1d81e5b5cdf3764f4fdb14a25d25a099 121 SMART SM00418 32 112 3.6E-32 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_17215 1d81e5b5cdf3764f4fdb14a25d25a099 121 Gene3D G3DSA:1.10.10.10 15 117 6.6E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17215 1d81e5b5cdf3764f4fdb14a25d25a099 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 1.5E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_17215 1d81e5b5cdf3764f4fdb14a25d25a099 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.5E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_17215 1d81e5b5cdf3764f4fdb14a25d25a099 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 1.5E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_17215 1d81e5b5cdf3764f4fdb14a25d25a099 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 49 1.5E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_12215 4e391ed44bbf9d30707a07e265de061f 244 Gene3D G3DSA:3.40.50.1110 40 243 1.3E-63 T 12-10-2018 IPR036514 SGNH hydrolase superfamily TL08_12215 4e391ed44bbf9d30707a07e265de061f 244 SUPERFAMILY SSF52266 33 236 4.43E-33 T 12-10-2018 TL08_12215 4e391ed44bbf9d30707a07e265de061f 244 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 45 224 2.6E-17 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain TL08_23335 699f1d1791d44aa5870fdbdd44592267 511 Gene3D G3DSA:1.20.1740.10 24 494 6.6E-114 T 12-10-2018 TL08_23335 699f1d1791d44aa5870fdbdd44592267 511 PIRSF PIRSF006060 6 502 6.9E-87 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TL08_23335 699f1d1791d44aa5870fdbdd44592267 511 Pfam PF13520 Amino acid permease 30 459 1.2E-49 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TL08_16410 e3979da73f6754f45df73025ae1eae44 577 Gene3D G3DSA:3.40.50.970 1 173 5.0E-53 T 12-10-2018 TL08_16410 e3979da73f6754f45df73025ae1eae44 577 Gene3D G3DSA:3.40.50.970 349 573 1.5E-64 T 12-10-2018 TL08_16410 e3979da73f6754f45df73025ae1eae44 577 SUPERFAMILY SSF52467 182 351 9.51E-43 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TL08_16410 e3979da73f6754f45df73025ae1eae44 577 SUPERFAMILY SSF52518 1 169 1.33E-40 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_16410 e3979da73f6754f45df73025ae1eae44 577 Gene3D G3DSA:3.40.50.1220 179 332 3.0E-47 T 12-10-2018 TL08_16410 e3979da73f6754f45df73025ae1eae44 577 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 318 3.9E-30 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TL08_16410 e3979da73f6754f45df73025ae1eae44 577 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TL08_16410 e3979da73f6754f45df73025ae1eae44 577 SUPERFAMILY SSF52518 357 557 6.28E-58 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_16410 e3979da73f6754f45df73025ae1eae44 577 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 167 8.7E-39 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TL08_16410 e3979da73f6754f45df73025ae1eae44 577 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 526 6.9E-38 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TL08_16985 6c30d745824486dc40140b9144c139e2 177 Pfam PF16859 Bacterial transcriptional repressor C-terminal 62 166 4.0E-20 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TL08_16985 6c30d745824486dc40140b9144c139e2 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 49 3.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16985 6c30d745824486dc40140b9144c139e2 177 SUPERFAMILY SSF48498 64 171 1.33E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_16985 6c30d745824486dc40140b9144c139e2 177 SUPERFAMILY SSF46689 3 56 4.08E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16985 6c30d745824486dc40140b9144c139e2 177 Gene3D G3DSA:1.10.10.60 1 42 3.2E-15 T 12-10-2018 TL08_16985 6c30d745824486dc40140b9144c139e2 177 Gene3D G3DSA:1.10.357.10 45 173 3.3E-23 T 12-10-2018 TL08_18975 52acb66b0476b2e6524536451a6299e9 226 Pfam PF00005 ABC transporter 23 171 2.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_18975 52acb66b0476b2e6524536451a6299e9 226 Gene3D G3DSA:3.40.50.300 2 224 3.5E-65 T 12-10-2018 TL08_18975 52acb66b0476b2e6524536451a6299e9 226 SMART SM00382 31 219 1.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_18975 52acb66b0476b2e6524536451a6299e9 226 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_18975 52acb66b0476b2e6524536451a6299e9 226 SUPERFAMILY SSF52540 3 220 3.25E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01630 b12596ecae85c8e979b4b5ec4108e6c4 175 ProSitePatterns PS01117 MarR-type HTH domain signature. 80 114 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TL08_01630 b12596ecae85c8e979b4b5ec4108e6c4 175 SMART SM00347 42 141 4.9E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_01630 b12596ecae85c8e979b4b5ec4108e6c4 175 SUPERFAMILY SSF46785 25 156 1.94E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_01630 b12596ecae85c8e979b4b5ec4108e6c4 175 Pfam PF12802 MarR family 52 105 4.6E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_01630 b12596ecae85c8e979b4b5ec4108e6c4 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 101 117 5.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_01630 b12596ecae85c8e979b4b5ec4108e6c4 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 81 5.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_01630 b12596ecae85c8e979b4b5ec4108e6c4 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 131 151 5.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_01630 b12596ecae85c8e979b4b5ec4108e6c4 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 97 5.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_01630 b12596ecae85c8e979b4b5ec4108e6c4 175 Gene3D G3DSA:1.10.10.10 2 157 6.9E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_27065 4be175a714bde05e157b2a446efb49b9 568 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 41 558 5.3E-79 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TL08_27065 4be175a714bde05e157b2a446efb49b9 568 PRINTS PR01806 Virulence factor MviN signature 72 91 1.9E-22 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TL08_27065 4be175a714bde05e157b2a446efb49b9 568 PRINTS PR01806 Virulence factor MviN signature 91 107 1.9E-22 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TL08_27065 4be175a714bde05e157b2a446efb49b9 568 PRINTS PR01806 Virulence factor MviN signature 305 331 1.9E-22 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TL08_27065 4be175a714bde05e157b2a446efb49b9 568 PRINTS PR01806 Virulence factor MviN signature 194 215 1.9E-22 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TL08_27065 4be175a714bde05e157b2a446efb49b9 568 PRINTS PR01806 Virulence factor MviN signature 402 421 1.9E-22 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TL08_27065 4be175a714bde05e157b2a446efb49b9 568 PRINTS PR01806 Virulence factor MviN signature 170 194 1.9E-22 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TL08_27065 4be175a714bde05e157b2a446efb49b9 568 Pfam PF03023 MviN-like protein 71 510 4.2E-89 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 5.5E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 5.5E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 5.5E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 5.5E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 5.5E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 Gene3D G3DSA:3.50.50.60 121 232 1.5E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 SUPERFAMILY SSF51905 1 303 1.73E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 294 1.2E-17 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 Gene3D G3DSA:3.50.50.60 5 302 1.5E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 8.2E-13 T 12-10-2018 TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 8.2E-13 T 12-10-2018 TL08_14010 75bf48e5c7c2599a2b76dae1965511bf 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 8.2E-13 T 12-10-2018 TL08_17120 95f1662e587e5d90c066cb59e81bf2be 476 PRINTS PR00359 B-class P450 signature 215 237 5.3E-7 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17120 95f1662e587e5d90c066cb59e81bf2be 476 PRINTS PR00359 B-class P450 signature 116 127 5.3E-7 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17120 95f1662e587e5d90c066cb59e81bf2be 476 PRINTS PR00359 B-class P450 signature 162 178 5.3E-7 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17120 95f1662e587e5d90c066cb59e81bf2be 476 PRINTS PR00359 B-class P450 signature 356 365 5.3E-7 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17120 95f1662e587e5d90c066cb59e81bf2be 476 SUPERFAMILY SSF48264 19 416 1.02E-58 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17120 95f1662e587e5d90c066cb59e81bf2be 476 Gene3D G3DSA:1.10.630.10 25 421 7.9E-84 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_03625 8747385e1412e867df6e22ef325f26c6 339 SMART SM00930 257 330 2.0E-10 T 12-10-2018 IPR018449 NIL domain TL08_03625 8747385e1412e867df6e22ef325f26c6 339 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_03625 8747385e1412e867df6e22ef325f26c6 339 SUPERFAMILY SSF52540 1 238 1.44E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03625 8747385e1412e867df6e22ef325f26c6 339 SMART SM00382 30 217 3.4E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_03625 8747385e1412e867df6e22ef325f26c6 339 SUPERFAMILY SSF55021 241 327 3.2E-8 T 12-10-2018 TL08_03625 8747385e1412e867df6e22ef325f26c6 339 Pfam PF09383 NIL domain 262 326 6.9E-9 T 12-10-2018 IPR018449 NIL domain TL08_03625 8747385e1412e867df6e22ef325f26c6 339 Pfam PF00005 ABC transporter 21 169 3.0E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_03625 8747385e1412e867df6e22ef325f26c6 339 Gene3D G3DSA:3.40.50.300 1 262 5.6E-83 T 12-10-2018 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 12-10-2018 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 SUPERFAMILY SSF47413 10 68 1.09E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 Gene3D G3DSA:3.40.50.2300 64 320 4.4E-57 T 12-10-2018 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 6.0E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 22 32 6.0E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 2.4E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 Pfam PF13377 Periplasmic binding protein-like domain 182 342 5.8E-28 T 12-10-2018 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 Gene3D G3DSA:1.10.260.40 2 63 1.8E-23 T 12-10-2018 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 SMART SM00354 10 80 2.1E-27 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 Gene3D G3DSA:3.40.50.2300 174 303 4.4E-57 T 12-10-2018 TL08_24735 fa495dfd533db3269e48dea780b1b292 343 SUPERFAMILY SSF53822 83 342 6.85E-53 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_06735 2767f09053aae620afe58a36477860c2 1036 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 531 834 6.2E-64 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_06735 2767f09053aae620afe58a36477860c2 1036 SUPERFAMILY SSF53901 9 434 6.65E-81 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_06735 2767f09053aae620afe58a36477860c2 1036 Gene3D G3DSA:3.40.50.1820 934 1035 1.0E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06735 2767f09053aae620afe58a36477860c2 1036 Gene3D G3DSA:3.40.366.10 527 818 6.9E-121 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_06735 2767f09053aae620afe58a36477860c2 1036 SUPERFAMILY SSF55048 649 702 5.1E-7 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_06735 2767f09053aae620afe58a36477860c2 1036 Pfam PF00698 Acyl transferase domain 531 804 2.4E-37 T 12-10-2018 IPR014043 Acyl transferase TL08_06735 2767f09053aae620afe58a36477860c2 1036 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 269 386 2.3E-38 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_06735 2767f09053aae620afe58a36477860c2 1036 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 174 190 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_06735 2767f09053aae620afe58a36477860c2 1036 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 260 1.3E-64 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_06735 2767f09053aae620afe58a36477860c2 1036 SMART SM00825 Beta-ketoacyl synthase 13 438 2.0E-161 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_06735 2767f09053aae620afe58a36477860c2 1036 SUPERFAMILY SSF47336 938 1010 1.07E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_06735 2767f09053aae620afe58a36477860c2 1036 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 389 498 1.0E-18 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_06735 2767f09053aae620afe58a36477860c2 1036 SMART SM00823 Phosphopantetheine attachment site 945 1014 3.2E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_06735 2767f09053aae620afe58a36477860c2 1036 Gene3D G3DSA:3.40.47.10 9 439 2.0E-156 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_06735 2767f09053aae620afe58a36477860c2 1036 Gene3D G3DSA:3.30.70.3290 451 847 6.9E-121 T 12-10-2018 TL08_06735 2767f09053aae620afe58a36477860c2 1036 Pfam PF00550 Phosphopantetheine attachment site 947 1010 3.0E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_06735 2767f09053aae620afe58a36477860c2 1036 Gene3D G3DSA:3.30.70.250 650 713 6.9E-121 T 12-10-2018 TL08_06735 2767f09053aae620afe58a36477860c2 1036 SUPERFAMILY SSF52151 528 808 4.71E-52 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 Pfam PF00083 Sugar (and other) transporter 27 471 1.1E-99 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 ProSitePatterns PS00216 Sugar transport proteins signature 1. 325 342 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 PRINTS PR00171 Sugar transporter signature 117 136 8.0E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 PRINTS PR00171 Sugar transporter signature 400 412 8.0E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 PRINTS PR00171 Sugar transporter signature 377 398 8.0E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 PRINTS PR00171 Sugar transporter signature 281 291 8.0E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 PRINTS PR00171 Sugar transporter signature 34 44 8.0E-25 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 SUPERFAMILY SSF103473 17 470 1.44E-65 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 Gene3D G3DSA:1.20.1250.20 17 471 2.8E-118 T 12-10-2018 TL08_26615 06fa26e3f059dc0b9df61268dc52e01a 471 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 15 471 3.2E-102 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_06570 2d83f5aff7f80e7a202e39bc334798f3 130 SUPERFAMILY SSF52821 8 126 9.3E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_06570 2d83f5aff7f80e7a202e39bc334798f3 130 Gene3D G3DSA:3.40.250.10 1 123 5.1E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_06570 2d83f5aff7f80e7a202e39bc334798f3 130 Pfam PF00581 Rhodanese-like domain 19 116 7.5E-11 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_06570 2d83f5aff7f80e7a202e39bc334798f3 130 SMART SM00450 16 120 1.6E-16 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_16930 414f3b63cd2e8afe9e56686d81cb0f0e 323 Pfam PF05448 Acetyl xylan esterase (AXE1) 20 307 8.0E-68 T 12-10-2018 IPR008391 Acetyl xylan esterase TL08_16930 414f3b63cd2e8afe9e56686d81cb0f0e 323 SUPERFAMILY SSF53474 21 313 1.02E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16930 414f3b63cd2e8afe9e56686d81cb0f0e 323 Gene3D G3DSA:3.40.50.1820 4 309 1.2E-74 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07395 c25d32fd119d642051100e6639e91614 271 Pfam PF00005 ABC transporter 34 192 1.0E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_07395 c25d32fd119d642051100e6639e91614 271 SMART SM00382 43 241 2.0E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_07395 c25d32fd119d642051100e6639e91614 271 PIRSF PIRSF039085 15 269 8.7E-99 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TL08_07395 c25d32fd119d642051100e6639e91614 271 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_07395 c25d32fd119d642051100e6639e91614 271 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 19 268 8.2E-112 T 12-10-2018 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein TL08_07395 c25d32fd119d642051100e6639e91614 271 SUPERFAMILY SSF52540 19 263 9.94E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07395 c25d32fd119d642051100e6639e91614 271 Gene3D G3DSA:3.40.50.300 16 271 6.5E-81 T 12-10-2018 TL08_01605 10b198bc70a34028d87e52eee7231e94 203 Pfam PF13302 Acetyltransferase (GNAT) domain 36 174 3.3E-20 T 12-10-2018 IPR000182 GNAT domain TL08_01605 10b198bc70a34028d87e52eee7231e94 203 SUPERFAMILY SSF55729 30 199 3.92E-38 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_01605 10b198bc70a34028d87e52eee7231e94 203 Gene3D G3DSA:3.40.630.30 30 200 2.2E-37 T 12-10-2018 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 219 7.0E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 SUPERFAMILY SSF52172 8 134 3.13E-32 T 12-10-2018 IPR011006 CheY-like superfamily TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 5.3E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 5.3E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 5.3E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 SMART SM00448 8 121 6.6E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 SMART SM00421 163 220 7.8E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 Gene3D G3DSA:3.40.50.12740 8 224 3.3E-60 T 12-10-2018 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 Pfam PF00072 Response regulator receiver domain 10 121 1.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_07800 ac37a65528fc5b47fab7c7a854a8b53b 225 SUPERFAMILY SSF46894 155 221 3.74E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_05485 3bcfbbf436bfc6de53dd2e6e065e33be 227 Pfam PF11361 Protein of unknown function (DUF3159) 31 214 1.1E-55 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 TL08_05485 3bcfbbf436bfc6de53dd2e6e065e33be 227 PIRSF PIRSF010219 7 226 7.1E-59 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 TL08_10470 ea813af2ab05e12133835faaf49fa0c4 418 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 246 1.3E-30 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_10470 ea813af2ab05e12133835faaf49fa0c4 418 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 277 366 3.7E-18 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_10470 ea813af2ab05e12133835faaf49fa0c4 418 SMART SM00825 Beta-ketoacyl synthase 10 412 0.0075 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_10470 ea813af2ab05e12133835faaf49fa0c4 418 Gene3D G3DSA:3.40.47.10 264 411 2.6E-35 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_10470 ea813af2ab05e12133835faaf49fa0c4 418 SUPERFAMILY SSF53901 218 408 7.95E-44 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_10470 ea813af2ab05e12133835faaf49fa0c4 418 Gene3D G3DSA:3.40.47.10 10 263 2.2E-53 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_10470 ea813af2ab05e12133835faaf49fa0c4 418 SUPERFAMILY SSF53901 9 253 1.13E-55 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_08290 fdc21b528bffc258df77c87080735a85 304 SMART SM00244 72 236 2.6E-9 T 12-10-2018 IPR001107 Band 7 domain TL08_08290 fdc21b528bffc258df77c87080735a85 304 Gene3D G3DSA:3.30.479.30 103 238 5.6E-10 T 12-10-2018 TL08_08290 fdc21b528bffc258df77c87080735a85 304 Pfam PF01145 SPFH domain / Band 7 family 76 248 2.7E-23 T 12-10-2018 IPR001107 Band 7 domain TL08_08290 fdc21b528bffc258df77c87080735a85 304 SUPERFAMILY SSF117892 107 237 1.83E-12 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily TL08_02130 1d69865699adfdf9620de05be0775fda 421 Gene3D G3DSA:3.40.190.10 29 415 3.2E-77 T 12-10-2018 TL08_02130 1d69865699adfdf9620de05be0775fda 421 Pfam PF01547 Bacterial extracellular solute-binding protein 55 338 6.7E-43 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_02130 1d69865699adfdf9620de05be0775fda 421 SUPERFAMILY SSF53850 19 418 2.3E-75 T 12-10-2018 TL08_10025 7042d4927df45a67c995bdd14856cad1 338 Gene3D G3DSA:3.40.50.620 10 338 4.1E-108 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_10025 7042d4927df45a67c995bdd14856cad1 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 19 35 2.7E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TL08_10025 7042d4927df45a67c995bdd14856cad1 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 2.7E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TL08_10025 7042d4927df45a67c995bdd14856cad1 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 218 2.7E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TL08_10025 7042d4927df45a67c995bdd14856cad1 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 153 174 2.7E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TL08_10025 7042d4927df45a67c995bdd14856cad1 338 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 7 338 5.3E-83 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TL08_10025 7042d4927df45a67c995bdd14856cad1 338 SUPERFAMILY SSF52374 10 338 8.7E-78 T 12-10-2018 TL08_10025 7042d4927df45a67c995bdd14856cad1 338 Pfam PF00579 tRNA synthetases class I (W and Y) 10 291 6.4E-54 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_10025 7042d4927df45a67c995bdd14856cad1 338 Gene3D G3DSA:1.10.240.10 203 306 4.1E-108 T 12-10-2018 TL08_10025 7042d4927df45a67c995bdd14856cad1 338 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_13110 2d20e2f68e01a12a5d593f652268e6cb 263 Gene3D G3DSA:3.40.50.150 78 262 1.3E-18 T 12-10-2018 TL08_13110 2d20e2f68e01a12a5d593f652268e6cb 263 SUPERFAMILY SSF53335 85 238 7.99E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13110 2d20e2f68e01a12a5d593f652268e6cb 263 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 120 191 1.3E-8 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 Gene3D G3DSA:3.50.50.60 4 330 5.0E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 Gene3D G3DSA:3.50.50.60 153 274 5.0E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 2 458 6.7E-201 T 12-10-2018 IPR017817 Mycothione reductase MetaCyc: PWY-6421 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PIRSF PIRSF000350 1 447 4.6E-87 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 SUPERFAMILY SSF55424 342 456 3.44E-31 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.5E-25 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 8.5E-25 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 8.5E-25 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 8.5E-25 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 8.5E-25 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 SUPERFAMILY SSF51905 2 317 1.13E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 Gene3D G3DSA:3.30.390.30 344 461 1.3E-34 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 320 4.9E-47 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 453 1.7E-26 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 7.1E-43 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 7.1E-43 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.1E-43 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 7.1E-43 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 7.1E-43 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 7.1E-43 T 12-10-2018 TL08_09015 14c84a4e77d11ecd74c61d9a42294bf2 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 7.1E-43 T 12-10-2018 TL08_20045 6ad5d85ad01b50c927c970cd553ad98e 226 Gene3D G3DSA:3.30.70.1200 1 90 1.1E-23 T 12-10-2018 TL08_20045 6ad5d85ad01b50c927c970cd553ad98e 226 Pfam PF08798 CRISPR associated protein 2 221 9.8E-56 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 TL08_20045 6ad5d85ad01b50c927c970cd553ad98e 226 Gene3D G3DSA:3.30.70.1210 94 221 1.2E-29 T 12-10-2018 TL08_20045 6ad5d85ad01b50c927c970cd553ad98e 226 SUPERFAMILY SSF117987 1 80 6.28E-20 T 12-10-2018 TL08_20045 6ad5d85ad01b50c927c970cd553ad98e 226 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 3 221 1.8E-22 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 TL08_20045 6ad5d85ad01b50c927c970cd553ad98e 226 SUPERFAMILY SSF117987 95 221 3.14E-27 T 12-10-2018 TL08_20045 6ad5d85ad01b50c927c970cd553ad98e 226 SMART SM01101 1 221 5.2E-67 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 TL08_24185 293fd9a3a6655837942a4fc227afce33 228 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 24 226 2.4E-71 T 12-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TL08_24185 293fd9a3a6655837942a4fc227afce33 228 SUPERFAMILY SSF53271 24 226 6.95E-59 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_24185 293fd9a3a6655837942a4fc227afce33 228 Pfam PF14681 Uracil phosphoribosyltransferase 26 227 1.4E-59 T 12-10-2018 TL08_24185 293fd9a3a6655837942a4fc227afce33 228 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 23 228 39.418 T 12-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TL08_24185 293fd9a3a6655837942a4fc227afce33 228 Gene3D G3DSA:3.40.50.2020 19 227 1.4E-69 T 12-10-2018 TL08_02065 ff78721360b916bf527b41513083eb2c 297 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 1.6E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_02065 ff78721360b916bf527b41513083eb2c 297 SMART SM00829 10 295 3.0E-12 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_02065 ff78721360b916bf527b41513083eb2c 297 Pfam PF13602 Zinc-binding dehydrogenase 197 295 3.1E-9 T 12-10-2018 TL08_02065 ff78721360b916bf527b41513083eb2c 297 SUPERFAMILY SSF51735 111 234 2.13E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_02065 ff78721360b916bf527b41513083eb2c 297 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 138 159 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TL08_02065 ff78721360b916bf527b41513083eb2c 297 Gene3D G3DSA:3.90.180.10 8 293 1.7E-71 T 12-10-2018 TL08_02065 ff78721360b916bf527b41513083eb2c 297 Gene3D G3DSA:3.40.50.720 122 246 1.7E-71 T 12-10-2018 TL08_02065 ff78721360b916bf527b41513083eb2c 297 SUPERFAMILY SSF50129 1 147 1.67E-30 T 12-10-2018 IPR011032 GroES-like superfamily TL08_11545 51430d0dd2656c0f26fd04b1ed90e428 65 Gene3D G3DSA:3.30.70.20 1 65 4.5E-20 T 12-10-2018 TL08_11545 51430d0dd2656c0f26fd04b1ed90e428 65 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 5.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_11545 51430d0dd2656c0f26fd04b1ed90e428 65 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 5.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_11545 51430d0dd2656c0f26fd04b1ed90e428 65 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 5.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_11545 51430d0dd2656c0f26fd04b1ed90e428 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 2.4E-13 T 12-10-2018 TL08_11545 51430d0dd2656c0f26fd04b1ed90e428 65 SUPERFAMILY SSF54862 2 62 2.66E-13 T 12-10-2018 TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 Pfam PF01336 OB-fold nucleic acid binding domain 1053 1128 4.0E-7 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 SUPERFAMILY SSF89550 100 308 3.73E-23 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 391 806 4.7E-140 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 99 1140 12.757 T 12-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 100 981 2.3E-199 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 SMART SM00481 100 167 1.0E-25 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 Pfam PF02811 PHP domain 101 270 4.0E-32 T 12-10-2018 IPR004013 PHP domain GO:0003824 TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 Gene3D G3DSA:3.20.20.140 66 369 4.2E-83 T 12-10-2018 TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 Pfam PF14579 Helix-hairpin-helix motif 879 974 1.4E-22 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_24550 d24320be42c000eef9d6c223508d79fa 1140 Gene3D G3DSA:2.40.50.140 1034 1126 2.1E-5 T 12-10-2018 TL08_18120 7d4ef5bf38fdcff0a3b0b37b797e4254 403 Gene3D G3DSA:3.10.20.340 278 403 1.3E-40 T 12-10-2018 TL08_18120 7d4ef5bf38fdcff0a3b0b37b797e4254 403 Gene3D G3DSA:3.60.70.12 10 198 4.3E-69 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TL08_18120 7d4ef5bf38fdcff0a3b0b37b797e4254 403 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 19 402 5.4E-113 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TL08_18120 7d4ef5bf38fdcff0a3b0b37b797e4254 403 SUPERFAMILY SSF56266 24 399 2.49E-125 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TL08_18120 7d4ef5bf38fdcff0a3b0b37b797e4254 403 Pfam PF01960 ArgJ family 28 403 2.1E-132 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TL08_18120 7d4ef5bf38fdcff0a3b0b37b797e4254 403 Gene3D G3DSA:3.30.2330.10 199 277 1.5E-26 T 12-10-2018 TL08_18120 7d4ef5bf38fdcff0a3b0b37b797e4254 403 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 403 131.393 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TL08_18120 7d4ef5bf38fdcff0a3b0b37b797e4254 403 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 42 401 1.0E-94 T 12-10-2018 TL08_19690 2217704403dc929ddd7a194c38528446 374 SMART SM00382 52 246 7.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_19690 2217704403dc929ddd7a194c38528446 374 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_19690 2217704403dc929ddd7a194c38528446 374 Gene3D G3DSA:3.40.50.300 17 336 1.6E-93 T 12-10-2018 TL08_19690 2217704403dc929ddd7a194c38528446 374 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 316 2.9E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_19690 2217704403dc929ddd7a194c38528446 374 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 246 325 1.5E-23 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_19690 2217704403dc929ddd7a194c38528446 374 SUPERFAMILY SSF52540 19 267 8.48E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19690 2217704403dc929ddd7a194c38528446 374 Pfam PF00005 ABC transporter 43 196 7.8E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 SMART SM01193 4 134 6.7E-86 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 SMART SM01192 139 423 3.7E-215 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 418 3.1E-130 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 PRINTS PR00148 Enolase signature 332 346 1.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 PRINTS PR00148 Enolase signature 361 378 1.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 PRINTS PR00148 Enolase signature 161 174 1.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 PRINTS PR00148 Enolase signature 107 123 1.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 PRINTS PR00148 Enolase signature 309 320 1.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 PRINTS PR00148 Enolase signature 37 51 1.3E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 PIRSF PIRSF001400 1 422 2.0E-189 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 7.1E-205 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 Pfam PF03952 Enolase, N-terminal domain 4 134 1.3E-56 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 Gene3D G3DSA:3.20.20.120 128 423 1.1E-131 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 Hamap MF_00318 Enolase [eno]. 2 409 45.168 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 SUPERFAMILY SSF51604 138 421 3.54E-126 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 Gene3D G3DSA:3.30.390.10 1 127 2.4E-53 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 ProSitePatterns PS00164 Enolase signature. 332 345 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_03770 9c0c2e1bacb1ed32c4386fdca0f9e881 428 SUPERFAMILY SSF54826 4 136 1.7E-51 T 12-10-2018 TL08_20410 9140d151054ae758bbff71e1b604e954 113 Gene3D G3DSA:3.30.60.230 1 60 2.1E-24 T 12-10-2018 TL08_20410 9140d151054ae758bbff71e1b604e954 113 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 111 8.0E-22 T 12-10-2018 IPR024412 Lsr2 TL08_20410 9140d151054ae758bbff71e1b604e954 113 Pfam PF11774 Lsr2 2 111 1.0E-39 T 12-10-2018 IPR024412 Lsr2 TL08_20410 9140d151054ae758bbff71e1b604e954 113 Gene3D G3DSA:1.20.890.50 79 113 2.3E-15 T 12-10-2018 TL08_26490 7f72e0ce4cd5bddc366bb1504012f7d4 125 Pfam PF02675 S-adenosylmethionine decarboxylase 3 107 2.8E-22 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TL08_26490 7f72e0ce4cd5bddc366bb1504012f7d4 125 SUPERFAMILY SSF56276 3 107 5.1E-24 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TL08_26490 7f72e0ce4cd5bddc366bb1504012f7d4 125 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 107 6.8E-23 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TL08_26490 7f72e0ce4cd5bddc366bb1504012f7d4 125 Gene3D G3DSA:3.60.90.10 2 117 9.1E-26 T 12-10-2018 TL08_17335 ffa2826b12507c34c90d9de47abb3aa8 364 Gene3D G3DSA:3.20.20.190 50 364 4.5E-119 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_17335 ffa2826b12507c34c90d9de47abb3aa8 364 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 126 218 1.5E-9 T 12-10-2018 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent TL08_17335 ffa2826b12507c34c90d9de47abb3aa8 364 SUPERFAMILY SSF51695 52 243 3.87E-10 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_19455 72c893312f875015cc3b8c8086ffb75d 270 SMART SM00422 2 72 1.9E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_19455 72c893312f875015cc3b8c8086ffb75d 270 Gene3D G3DSA:3.20.80.10 120 270 8.3E-22 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily TL08_19455 72c893312f875015cc3b8c8086ffb75d 270 Pfam PF06445 GyrI-like small molecule binding domain 120 265 3.2E-9 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain TL08_19455 72c893312f875015cc3b8c8086ffb75d 270 Pfam PF13411 MerR HTH family regulatory protein 4 71 2.1E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_19455 72c893312f875015cc3b8c8086ffb75d 270 SUPERFAMILY SSF55136 120 269 3.4E-14 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily TL08_19455 72c893312f875015cc3b8c8086ffb75d 270 Gene3D G3DSA:1.10.1660.10 1 119 8.8E-22 T 12-10-2018 TL08_19455 72c893312f875015cc3b8c8086ffb75d 270 SUPERFAMILY SSF46955 2 116 4.03E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_19455 72c893312f875015cc3b8c8086ffb75d 270 SMART SM00871 119 270 1.9E-12 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding TL08_13945 521f7e032a2b90826975c094bc387bec 246 SUPERFAMILY SSF54593 121 230 5.92E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_13945 521f7e032a2b90826975c094bc387bec 246 Gene3D G3DSA:3.10.180.10 115 229 2.0E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_11345 e083c91ebe1901d5784fa8bab8ff6772 541 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 112 430 1.1E-44 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 TL08_11345 e083c91ebe1901d5784fa8bab8ff6772 541 Gene3D G3DSA:3.90.1150.170 68 485 6.2E-109 T 12-10-2018 TL08_11345 e083c91ebe1901d5784fa8bab8ff6772 541 Gene3D G3DSA:3.40.640.10 126 375 6.2E-109 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_11345 e083c91ebe1901d5784fa8bab8ff6772 541 SUPERFAMILY SSF53383 69 497 5.24E-103 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 Gene3D G3DSA:3.90.740.10 214 410 1.7E-226 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 Pfam PF08264 Anticodon-binding domain of tRNA 710 849 6.7E-21 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 14 1048 13.809 T 12-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 SUPERFAMILY SSF50677 217 406 4.4E-49 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 648 2.2E-182 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 Gene3D G3DSA:1.10.730.10 656 841 2.1E-37 T 12-10-2018 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 Gene3D G3DSA:3.40.50.620 26 640 1.7E-226 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 SUPERFAMILY SSF47323 668 890 2.8E-42 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 SUPERFAMILY SSF52374 16 645 4.29E-123 T 12-10-2018 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 17 861 1.2E-240 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 63 74 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 236 259 2.6E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 404 419 2.6E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 56 67 2.6E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 573 582 2.6E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TL08_09560 59353fa4907ab65c2efb9a400d6824b8 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 533 546 2.6E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 SUPERFAMILY SSF51905 17 315 2.25E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 Gene3D G3DSA:3.50.50.60 19 311 1.6E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 293 1.9E-13 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 Gene3D G3DSA:3.50.50.60 135 245 1.6E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 2.3E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 156 2.3E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 159 183 2.3E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 122 130 2.3E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 2.3E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 8.3E-8 T 12-10-2018 TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 8.3E-8 T 12-10-2018 TL08_06875 cca7f8b12f0489a4dad4a7555ffb0b7e 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 121 139 8.3E-8 T 12-10-2018 TL08_25955 df618b8e846eab19d92a13593516b0d0 283 SUPERFAMILY SSF56752 5 279 1.01E-54 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TL08_25955 df618b8e846eab19d92a13593516b0d0 283 Gene3D G3DSA:3.20.10.10 116 281 1.1E-51 T 12-10-2018 TL08_25955 df618b8e846eab19d92a13593516b0d0 283 Pfam PF01063 Amino-transferase class IV 31 254 3.1E-42 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TL08_25955 df618b8e846eab19d92a13593516b0d0 283 Gene3D G3DSA:3.30.470.10 2 112 6.3E-31 T 12-10-2018 TL08_01020 46c7b35fb5afcfd1454b9218810f34fc 352 Gene3D G3DSA:3.40.50.360 1 204 3.1E-43 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_01020 46c7b35fb5afcfd1454b9218810f34fc 352 Pfam PF03358 NADPH-dependent FMN reductase 7 152 3.7E-31 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TL08_01020 46c7b35fb5afcfd1454b9218810f34fc 352 SUPERFAMILY SSF55729 208 340 4.61E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_01020 46c7b35fb5afcfd1454b9218810f34fc 352 Gene3D G3DSA:3.40.630.30 208 345 1.4E-17 T 12-10-2018 TL08_01020 46c7b35fb5afcfd1454b9218810f34fc 352 Pfam PF00583 Acetyltransferase (GNAT) family 241 335 3.0E-11 T 12-10-2018 IPR000182 GNAT domain TL08_01020 46c7b35fb5afcfd1454b9218810f34fc 352 SUPERFAMILY SSF52218 7 180 1.4E-32 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_22480 ab0d74ba165066a5e66ce3bd14438034 431 Pfam PF08241 Methyltransferase domain 238 333 9.8E-23 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_22480 ab0d74ba165066a5e66ce3bd14438034 431 Pfam PF04229 GrpB protein 29 187 4.7E-50 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase TL08_22480 ab0d74ba165066a5e66ce3bd14438034 431 SUPERFAMILY SSF81301 31 189 8.5E-46 T 12-10-2018 TL08_22480 ab0d74ba165066a5e66ce3bd14438034 431 Gene3D G3DSA:3.30.460.10 25 192 5.8E-49 T 12-10-2018 TL08_22480 ab0d74ba165066a5e66ce3bd14438034 431 Gene3D G3DSA:3.40.50.150 220 428 4.4E-46 T 12-10-2018 TL08_22480 ab0d74ba165066a5e66ce3bd14438034 431 SUPERFAMILY SSF53335 199 402 7.83E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_25480 6fa30d696d381ad182de94bd55850eed 214 SUPERFAMILY SSF88946 4 107 2.67E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_25480 6fa30d696d381ad182de94bd55850eed 214 Pfam PF04542 Sigma-70 region 2 28 95 9.5E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_25480 6fa30d696d381ad182de94bd55850eed 214 Gene3D G3DSA:1.10.10.10 106 190 1.1E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25480 6fa30d696d381ad182de94bd55850eed 214 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 186 4.1E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_25480 6fa30d696d381ad182de94bd55850eed 214 SUPERFAMILY SSF88659 106 188 3.36E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_25480 6fa30d696d381ad182de94bd55850eed 214 Gene3D G3DSA:1.10.1740.10 6 95 2.0E-17 T 12-10-2018 TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 Pfam PF00005 ABC transporter 642 782 3.0E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 SMART SM00382 650 838 3.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 45 310 1.5E-15 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 SMART SM00939 347 582 2.8E-6 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 SUPERFAMILY SSF53474 19 355 4.73E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 Gene3D G3DSA:3.40.50.300 625 863 1.5E-57 T 12-10-2018 TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 ProSitePatterns PS00211 ABC transporters family signature. 754 768 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 SUPERFAMILY SSF52540 621 846 1.18E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 SUPERFAMILY SSF49785 429 575 1.91E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 441 560 4.9E-6 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TL08_10295 9e3e5b04c1a024849eef677bb29d585d 923 Gene3D G3DSA:2.60.120.260 400 580 2.3E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_23470 472e34cde22e679459174078240320d7 289 Pfam PF00005 ABC transporter 15 153 4.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23470 472e34cde22e679459174078240320d7 289 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_23470 472e34cde22e679459174078240320d7 289 SUPERFAMILY SSF52540 1 218 3.18E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23470 472e34cde22e679459174078240320d7 289 SMART SM00382 23 223 9.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23470 472e34cde22e679459174078240320d7 289 Gene3D G3DSA:3.40.50.300 1 250 1.0E-57 T 12-10-2018 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 Gene3D G3DSA:3.40.1010.10 172 287 8.0E-38 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 174 407 1.8E-79 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 Gene3D G3DSA:3.30.950.10 288 416 3.2E-42 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 SUPERFAMILY SSF51735 19 116 1.48E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 SUPERFAMILY SSF53790 172 407 3.79E-71 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 Gene3D G3DSA:3.40.50.720 15 139 7.0E-29 T 12-10-2018 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 174 385 6.3E-48 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 19 139 2.0E-19 T 12-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 PIRSF PIRSF036426 146 413 1.2E-89 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 PIRSF PIRSF036426 11 164 2.7E-28 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TL08_09100 eb72f01b913ddcaf2528dd9423cec3a6 418 Pfam PF13241 Putative NAD(P)-binding 19 124 6.2E-20 T 12-10-2018 TL08_26910 0cdca95ce755db49b0c0a89422b1050e 285 Pfam PF00990 Diguanylate cyclase, GGDEF domain 139 245 4.8E-20 T 12-10-2018 IPR000160 GGDEF domain TL08_26910 0cdca95ce755db49b0c0a89422b1050e 285 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 138 241 1.5E-16 T 12-10-2018 IPR000160 GGDEF domain TL08_26910 0cdca95ce755db49b0c0a89422b1050e 285 SUPERFAMILY SSF55073 142 281 1.26E-20 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_26910 0cdca95ce755db49b0c0a89422b1050e 285 Gene3D G3DSA:3.30.70.270 136 284 9.0E-24 T 12-10-2018 TL08_26910 0cdca95ce755db49b0c0a89422b1050e 285 SMART SM00267 128 282 1.7E-6 T 12-10-2018 IPR000160 GGDEF domain TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 Pfam PF05746 DALR anticodon binding domain 466 582 1.9E-29 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 31 582 1.7E-141 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 127 138 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 SUPERFAMILY SSF52374 113 458 1.09E-83 T 12-10-2018 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 SUPERFAMILY SSF47323 460 582 7.19E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 Pfam PF00750 tRNA synthetases class I (R) 102 452 1.8E-102 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 Gene3D G3DSA:3.30.1360.70 5 110 6.4E-25 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 SMART SM01016 8 91 1.1E-22 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 310 331 6.1E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 158 171 6.1E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 134 6.1E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 134 150 6.1E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 Gene3D G3DSA:3.40.50.620 114 459 3.7E-96 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 13 91 1.5E-20 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 SUPERFAMILY SSF55190 13 102 4.32E-18 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 582 25.021 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 Gene3D G3DSA:1.10.730.10 460 582 5.1E-31 T 12-10-2018 TL08_00170 d1efeb93d749106b7a9de8292a33ca06 582 SMART SM00836 466 582 3.0E-39 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TL08_23875 3b1237c03b9f8677c2a82c2b87f02e08 408 Pfam PF07994 Myo-inositol-1-phosphate synthase 14 389 2.9E-41 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TL08_23875 3b1237c03b9f8677c2a82c2b87f02e08 408 SUPERFAMILY SSF55347 229 333 7.46E-27 T 12-10-2018 TL08_23875 3b1237c03b9f8677c2a82c2b87f02e08 408 PIRSF PIRSF015578 2 406 1.9E-79 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TL08_23875 3b1237c03b9f8677c2a82c2b87f02e08 408 Pfam PF01658 Myo-inositol-1-phosphate synthase 230 334 5.2E-24 T 12-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TL08_23875 3b1237c03b9f8677c2a82c2b87f02e08 408 Gene3D G3DSA:3.40.50.720 17 381 1.7E-122 T 12-10-2018 TL08_23875 3b1237c03b9f8677c2a82c2b87f02e08 408 SUPERFAMILY SSF51735 15 391 3.7E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_23875 3b1237c03b9f8677c2a82c2b87f02e08 408 Gene3D G3DSA:3.30.360.10 230 330 1.7E-122 T 12-10-2018 TL08_21430 681d10d3460a10af4a2b37a84bfab9fa 326 SUPERFAMILY SSF52402 34 233 2.43E-62 T 12-10-2018 TL08_21430 681d10d3460a10af4a2b37a84bfab9fa 326 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 35 326 1.1E-137 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TL08_21430 681d10d3460a10af4a2b37a84bfab9fa 326 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 56 280 2.4E-46 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TL08_21430 681d10d3460a10af4a2b37a84bfab9fa 326 PIRSF PIRSF002936 27 326 9.6E-133 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TL08_21430 681d10d3460a10af4a2b37a84bfab9fa 326 Gene3D G3DSA:3.40.50.620 33 236 2.3E-56 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 Gene3D G3DSA:1.10.10.10 391 468 3.0E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 259 272 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 Gene3D G3DSA:1.10.601.10 164 199 4.9E-9 T 12-10-2018 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 Gene3D G3DSA:1.10.601.10 200 307 1.9E-52 T 12-10-2018 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 428 454 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 63 468 32.991 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 SUPERFAMILY SSF88659 308 381 2.06E-22 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 Pfam PF04542 Sigma-70 region 2 235 304 1.7E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 Gene3D G3DSA:1.10.10.10 308 383 2.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 Pfam PF04545 Sigma-70, region 4 403 456 1.4E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 231 467 2.0E-113 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 Pfam PF00140 Sigma-70 factor, region 1.2 166 197 8.9E-16 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 Pfam PF04539 Sigma-70 region 3 314 389 1.6E-28 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 SUPERFAMILY SSF88946 163 305 1.28E-53 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 SUPERFAMILY SSF88659 367 467 2.88E-26 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 231 456 1.9E-35 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 PRINTS PR00046 Major sigma-70 factor signature 407 419 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 PRINTS PR00046 Major sigma-70 factor signature 259 272 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 PRINTS PR00046 Major sigma-70 factor signature 428 443 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 PRINTS PR00046 Major sigma-70 factor signature 443 454 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08380 b880f2dd1abfe3cbed2603e61d417e0b 468 PRINTS PR00046 Major sigma-70 factor signature 283 291 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_26270 5a8323aeb96e9f906faecace1417500e 670 Pfam PF00012 Hsp70 protein 89 352 7.1E-29 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26270 5a8323aeb96e9f906faecace1417500e 670 Gene3D G3DSA:3.90.640.10 206 292 2.7E-89 T 12-10-2018 TL08_26270 5a8323aeb96e9f906faecace1417500e 670 SUPERFAMILY SSF53067 4 155 9.71E-25 T 12-10-2018 TL08_26270 5a8323aeb96e9f906faecace1417500e 670 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 314 328 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TL08_26270 5a8323aeb96e9f906faecace1417500e 670 SUPERFAMILY SSF53067 168 353 2.18E-29 T 12-10-2018 TL08_26270 5a8323aeb96e9f906faecace1417500e 670 Gene3D G3DSA:3.30.420.40 167 342 2.7E-89 T 12-10-2018 TL08_26270 5a8323aeb96e9f906faecace1417500e 670 Gene3D G3DSA:3.30.420.40 4 352 2.7E-89 T 12-10-2018 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Gene3D G3DSA:3.90.470.20 1327 1443 1.6E-7 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 414 493 2.5E-9 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Pfam PF00698 Acyl transferase domain 599 788 8.5E-15 T 12-10-2018 IPR014043 Acyl transferase TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 SUPERFAMILY SSF56214 1338 1441 3.14E-7 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Gene3D G3DSA:3.90.470.20 1447 1547 1.1E-11 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Gene3D G3DSA:3.40.366.10 578 795 1.7E-38 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 SUPERFAMILY SSF56214 1446 1539 1.22E-14 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Gene3D G3DSA:3.30.70.250 644 711 1.7E-38 T 12-10-2018 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 SUPERFAMILY SSF52151 560 814 1.62E-24 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 282 2.1E-50 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Pfam PF14765 Polyketide synthase dehydratase 1038 1289 1.7E-10 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 1446 1557 1.2E-9 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 SUPERFAMILY SSF53901 5 457 7.7E-63 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 SMART SM00825 Beta-ketoacyl synthase 8 461 5.4E-70 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 563 802 8.3E-12 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 409 1.7E-29 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_18350 69a03492657b6d68e9bc1724911bafba 1569 SUPERFAMILY SSF55048 652 710 3.66E-5 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_22610 fe9edcbc531d3cdb8bbed12ecf881b6d 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 51 379 2.3E-77 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TL08_22610 fe9edcbc531d3cdb8bbed12ecf881b6d 381 SUPERFAMILY SSF53383 52 380 9.46E-71 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_22610 fe9edcbc531d3cdb8bbed12ecf881b6d 381 PIRSF PIRSF001434 5 381 2.7E-99 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TL08_22610 fe9edcbc531d3cdb8bbed12ecf881b6d 381 Gene3D G3DSA:3.90.1150.10 260 381 3.6E-30 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_22610 fe9edcbc531d3cdb8bbed12ecf881b6d 381 Gene3D G3DSA:3.40.640.10 11 259 4.7E-58 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_11790 3e463a7504e23c2ae0cb950b0f70551d 310 SMART SM00382 34 212 3.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_11790 3e463a7504e23c2ae0cb950b0f70551d 310 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_11790 3e463a7504e23c2ae0cb950b0f70551d 310 Pfam PF00005 ABC transporter 26 164 2.0E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_11790 3e463a7504e23c2ae0cb950b0f70551d 310 Gene3D G3DSA:3.40.50.300 3 234 2.3E-62 T 12-10-2018 TL08_11790 3e463a7504e23c2ae0cb950b0f70551d 310 SUPERFAMILY SSF52540 5 229 1.05E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 SUPERFAMILY SSF53738 311 456 1.88E-26 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 Gene3D G3DSA:3.40.120.10 210 330 1.4E-19 T 12-10-2018 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 55 189 5.0E-40 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 Gene3D G3DSA:3.40.120.10 45 197 8.4E-46 T 12-10-2018 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 150 159 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 SUPERFAMILY SSF53738 45 217 9.42E-43 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 332 449 9.1E-19 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 Gene3D G3DSA:3.30.310.50 463 539 4.3E-5 T 12-10-2018 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 478 529 3.7E-7 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 SUPERFAMILY SSF53738 212 318 1.18E-17 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 233 318 9.6E-21 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 303 318 5.6E-6 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 149 163 5.6E-6 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 Gene3D G3DSA:3.40.120.10 331 454 8.7E-27 T 12-10-2018 TL08_24035 8e9f47cb27c1cc17ab43e85461ef5c0b 583 SUPERFAMILY SSF55957 460 533 3.14E-9 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_23165 c881f9d1164d46730c97efc3446149bd 307 Gene3D G3DSA:3.40.50.10330 1 125 1.2E-33 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TL08_23165 c881f9d1164d46730c97efc3446149bd 307 Gene3D G3DSA:2.60.200.40 128 300 3.4E-18 T 12-10-2018 TL08_23165 c881f9d1164d46730c97efc3446149bd 307 SMART SM00046 2 131 1.6E-12 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TL08_23165 c881f9d1164d46730c97efc3446149bd 307 SUPERFAMILY SSF111331 2 306 2.22E-57 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TL08_23165 c881f9d1164d46730c97efc3446149bd 307 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 117 8.6E-28 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TL08_25010 4c347e16073ba2deefea7c7250fed86f 602 Gene3D G3DSA:3.40.50.12780 330 468 2.3E-37 T 12-10-2018 TL08_25010 4c347e16073ba2deefea7c7250fed86f 602 Pfam PF00501 AMP-binding enzyme 26 470 2.3E-95 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_25010 4c347e16073ba2deefea7c7250fed86f 602 SUPERFAMILY SSF56801 18 600 3.27E-108 T 12-10-2018 TL08_25010 4c347e16073ba2deefea7c7250fed86f 602 Gene3D G3DSA:3.40.50.12780 8 316 1.4E-49 T 12-10-2018 TL08_25010 4c347e16073ba2deefea7c7250fed86f 602 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 SUPERFAMILY SSF51569 12 300 1.88E-86 T 12-10-2018 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 16 291 2.4E-79 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 SMART SM01130 12 299 4.0E-112 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 50 67 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 145 175 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 Pfam PF00701 Dihydrodipicolinate synthetase family 13 290 6.0E-74 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 Gene3D G3DSA:3.20.20.70 7 302 3.8E-101 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 12 297 53.555 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 PIRSF PIRSF001365 10 304 1.9E-74 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 140 157 4.7E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 83 101 4.7E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 47 68 4.7E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09340 e368f1eff0a51e3f64f29fe31ebfeaf8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 115 131 4.7E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 SUPERFAMILY SSF50447 176 297 3.28E-24 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 SUPERFAMILY SSF54980 301 380 3.96E-19 T 12-10-2018 IPR035647 EF-G domain III/V-like TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 Pfam PF00679 Elongation factor G C-terminus 408 494 1.1E-21 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 Gene3D G3DSA:3.40.50.300 11 195 1.1E-68 T 12-10-2018 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 TIGRFAM TIGR01393 lepA: elongation factor 4 14 604 5.1E-290 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 16 184 1.1E-17 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 Gene3D G3DSA:3.30.70.3380 378 487 3.4E-38 T 12-10-2018 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 SUPERFAMILY SSF54980 408 503 1.82E-22 T 12-10-2018 IPR035647 EF-G domain III/V-like TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 Gene3D G3DSA:3.30.70.870 296 377 8.4E-35 T 12-10-2018 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 Pfam PF06421 GTP-binding protein LepA C-terminus 498 602 9.6E-49 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 Gene3D G3DSA:3.30.70.2570 489 563 3.0E-33 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 Pfam PF00009 Elongation factor Tu GTP binding domain 14 191 9.3E-51 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 PRINTS PR00315 GTP-binding elongation factor signature 60 68 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 PRINTS PR00315 GTP-binding elongation factor signature 17 30 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 SMART SM00838 410 491 3.5E-4 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 SUPERFAMILY SSF52540 9 214 3.7E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 282.578 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 TL08_08475 51abb751a15ca98ac4a32a5e55e08bfc 615 Gene3D G3DSA:2.40.30.10 196 295 2.5E-32 T 12-10-2018 TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 Pfam PF13522 Glutamine amidotransferase domain 72 209 3.0E-21 T 12-10-2018 TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 SUPERFAMILY SSF53697 261 628 1.02E-105 T 12-10-2018 TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 Gene3D G3DSA:3.60.20.10 9 256 7.0E-73 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 SUPERFAMILY SSF56235 9 248 1.46E-66 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 9 628 7.3E-247 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 Pfam PF01380 SIS domain 478 606 1.3E-20 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 Pfam PF01380 SIS domain 305 429 4.1E-32 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 Gene3D G3DSA:3.40.50.10490 462 613 4.8E-139 T 12-10-2018 TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 Gene3D G3DSA:3.40.50.10490 266 627 4.8E-139 T 12-10-2018 TL08_24875 bfe1bcdb9fd2e7269f77ac9498bc7933 628 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 8 628 40.625 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TL08_10430 b287397a05a8a261defac561beeb2598 126 Pfam PF04486 SchA/CurD like domain 1 119 1.1E-46 T 12-10-2018 IPR007575 SchA/CurD-like domain TL08_06060 ef5d6dd05d011c4e2e7b109751a89d52 468 SUPERFAMILY SSF53092 40 160 1.62E-21 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TL08_06060 ef5d6dd05d011c4e2e7b109751a89d52 468 SMART SM01011 37 174 8.5E-33 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 TL08_06060 ef5d6dd05d011c4e2e7b109751a89d52 468 SUPERFAMILY SSF55920 198 465 1.7E-59 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TL08_06060 ef5d6dd05d011c4e2e7b109751a89d52 468 Pfam PF05195 Aminopeptidase P, N-terminal domain 40 157 3.2E-18 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 TL08_06060 ef5d6dd05d011c4e2e7b109751a89d52 468 Gene3D G3DSA:3.90.230.10 197 468 1.0E-69 T 12-10-2018 TL08_06060 ef5d6dd05d011c4e2e7b109751a89d52 468 Pfam PF00557 Metallopeptidase family M24 206 441 3.8E-45 T 12-10-2018 IPR000994 Peptidase M24 TL08_06060 ef5d6dd05d011c4e2e7b109751a89d52 468 Gene3D G3DSA:3.40.350.10 36 169 1.8E-14 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TL08_24645 829cc7e29d2781d86c6de28d58165e90 435 Gene3D G3DSA:3.40.50.300 237 396 1.2E-6 T 12-10-2018 TL08_24645 829cc7e29d2781d86c6de28d58165e90 435 SUPERFAMILY SSF52540 2 367 2.27E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24645 829cc7e29d2781d86c6de28d58165e90 435 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 43 365 6.8E-31 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 759 1.2E-52 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Gene3D G3DSA:3.40.50.300 350 546 3.6E-72 T 12-10-2018 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 6.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 6.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 6.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 6.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 851 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 SUPERFAMILY SSF81923 7 157 1.28E-32 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 318 3.2E-12 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 SUPERFAMILY SSF52540 548 850 2.17E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Gene3D G3DSA:1.10.1780.10 7 147 1.4E-27 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 SMART SM01086 766 857 2.3E-35 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Gene3D G3DSA:1.10.8.60 766 864 5.0E-30 T 12-10-2018 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 846 3.8E-26 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 SMART SM00382 599 746 6.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 SMART SM00382 199 345 6.6E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 SUPERFAMILY SSF52540 161 547 1.7E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Gene3D G3DSA:3.40.50.300 159 349 4.1E-71 T 12-10-2018 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Gene3D G3DSA:3.40.50.300 552 765 7.4E-84 T 12-10-2018 TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 4.3E-13 T 12-10-2018 IPR004176 Clp, N-terminal TL08_26330 80eac2cbb13d28dc0a7980b7c1aec5b3 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 1.6E-9 T 12-10-2018 IPR004176 Clp, N-terminal TL08_13630 4768ea6bb69bf3eda00c32029c1c7639 249 Gene3D G3DSA:1.10.357.10 94 248 6.2E-36 T 12-10-2018 TL08_13630 4768ea6bb69bf3eda00c32029c1c7639 249 SUPERFAMILY SSF46689 24 90 2.19E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_13630 4768ea6bb69bf3eda00c32029c1c7639 249 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 96 237 1.8E-17 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 TL08_13630 4768ea6bb69bf3eda00c32029c1c7639 249 Gene3D G3DSA:1.10.10.60 11 86 2.7E-23 T 12-10-2018 TL08_13630 4768ea6bb69bf3eda00c32029c1c7639 249 SUPERFAMILY SSF48498 99 240 3.11E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_13630 4768ea6bb69bf3eda00c32029c1c7639 249 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 79 2.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 SUPERFAMILY SSF56553 48 169 3.4E-43 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 SMART SM00662 18 225 1.9E-97 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 SUPERFAMILY SSF55257 8 220 1.24E-25 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 320 3.0E-24 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 1.9E-25 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 243 302 1.4E-25 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 311 34.799 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 Gene3D G3DSA:1.10.150.20 239 311 2.3E-28 T 12-10-2018 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 Gene3D G3DSA:3.30.1360.10 12 216 1.7E-83 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 SUPERFAMILY SSF47789 246 318 1.02E-23 T 12-10-2018 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 7.0E-114 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 Gene3D G3DSA:2.170.120.12 48 168 1.7E-83 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_03135 ee5b719bd2ab35971b260e99e846271f 352 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.2E-19 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_12900 0c371c5f60f458ad812607fdbaa291df 322 Gene3D G3DSA:3.10.129.10 182 305 1.6E-18 T 12-10-2018 TL08_12900 0c371c5f60f458ad812607fdbaa291df 322 Gene3D G3DSA:3.10.129.10 1 144 5.6E-14 T 12-10-2018 TL08_12900 0c371c5f60f458ad812607fdbaa291df 322 Pfam PF01575 MaoC like domain 186 292 2.0E-6 T 12-10-2018 IPR002539 MaoC-like dehydratase domain TL08_12900 0c371c5f60f458ad812607fdbaa291df 322 SUPERFAMILY SSF54637 11 136 1.58E-14 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_12900 0c371c5f60f458ad812607fdbaa291df 322 SUPERFAMILY SSF54637 184 305 1.73E-15 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 238 398 1.3E-40 T 12-10-2018 IPR000160 GGDEF domain TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 SUPERFAMILY SSF55073 247 400 4.24E-45 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 Gene3D G3DSA:3.20.20.450 407 657 5.6E-77 T 12-10-2018 IPR035919 EAL domain superfamily TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 SUPERFAMILY SSF55785 125 229 2.62E-12 T 12-10-2018 IPR035965 PAS domain superfamily TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 Pfam PF00563 EAL domain 414 646 1.7E-64 T 12-10-2018 IPR001633 EAL domain TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 SMART SM00267 231 398 5.4E-54 T 12-10-2018 IPR000160 GGDEF domain TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 Pfam PF00990 Diguanylate cyclase, GGDEF domain 244 394 1.9E-39 T 12-10-2018 IPR000160 GGDEF domain TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 Gene3D G3DSA:3.30.70.270 236 405 1.3E-52 T 12-10-2018 TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 SMART SM00052 408 651 2.0E-66 T 12-10-2018 IPR001633 EAL domain TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 SMART SM00091 116 181 63.0 T 12-10-2018 IPR000014 PAS domain TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 SMART SM00091 6 73 0.0014 T 12-10-2018 IPR000014 PAS domain TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 SUPERFAMILY SSF55785 5 76 7.68E-7 T 12-10-2018 IPR035965 PAS domain superfamily TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 SUPERFAMILY SSF141868 414 655 2.62E-71 T 12-10-2018 IPR035919 EAL domain superfamily TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 Pfam PF08447 PAS fold 137 224 4.0E-10 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 Gene3D G3DSA:3.30.450.20 125 235 1.1E-17 T 12-10-2018 TL08_13940 9811dba84319ddc4e504393e5d6606e9 662 Gene3D G3DSA:3.30.450.20 2 108 1.4E-6 T 12-10-2018 TL08_18765 1b3d11cddc01fa55e24e493ddc2bf580 343 SMART SM01236 165 270 5.2E-40 T 12-10-2018 TL08_18765 1b3d11cddc01fa55e24e493ddc2bf580 343 SUPERFAMILY SSF48613 123 314 4.08E-15 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_18765 1b3d11cddc01fa55e24e493ddc2bf580 343 Pfam PF14518 Iron-containing redox enzyme 133 309 1.5E-49 T 12-10-2018 TL08_18765 1b3d11cddc01fa55e24e493ddc2bf580 343 Gene3D G3DSA:1.20.910.10 111 322 2.7E-33 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_03125 2076e3d2c207ff5afa30c9e8366310bb 135 SUPERFAMILY SSF53137 20 135 3.99E-49 T 12-10-2018 TL08_03125 2076e3d2c207ff5afa30c9e8366310bb 135 ProSitePatterns PS00054 Ribosomal protein S11 signature. 103 125 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site TL08_03125 2076e3d2c207ff5afa30c9e8366310bb 135 Pfam PF00411 Ribosomal protein S11 25 134 1.1E-48 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TL08_03125 2076e3d2c207ff5afa30c9e8366310bb 135 Gene3D G3DSA:3.30.420.80 9 135 8.8E-54 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TL08_03125 2076e3d2c207ff5afa30c9e8366310bb 135 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 135 33.894 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TL08_03125 2076e3d2c207ff5afa30c9e8366310bb 135 PIRSF PIRSF002131 6 135 1.9E-53 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TL08_03125 2076e3d2c207ff5afa30c9e8366310bb 135 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 16 132 1.5E-58 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_22275 5193b85ef5be0411ee303dcc1f63de9f 454 ProSitePatterns PS01219 Ammonium transporters signature. 169 194 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 TL08_22275 5193b85ef5be0411ee303dcc1f63de9f 454 Gene3D G3DSA:1.10.3430.10 1 420 7.0E-141 T 12-10-2018 IPR029020 Ammonium/urea transporter TL08_22275 5193b85ef5be0411ee303dcc1f63de9f 454 Pfam PF00909 Ammonium Transporter Family 7 413 2.1E-126 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 TL08_22275 5193b85ef5be0411ee303dcc1f63de9f 454 TIGRFAM TIGR00836 amt: ammonium transporter 5 413 8.3E-140 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 TL08_22275 5193b85ef5be0411ee303dcc1f63de9f 454 SUPERFAMILY SSF111352 2 394 1.06E-120 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 434 29.236 T 12-10-2018 IPR026593 Protein translocase subunit SecY TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 ProSitePatterns PS00755 Protein secY signature 1. 75 94 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 Pfam PF00344 SecY translocase 75 418 2.9E-116 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 Gene3D G3DSA:1.10.3370.10 1 430 8.3E-161 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 430 1.1E-129 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PIRSF PIRSF004557 1 435 2.5E-123 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 1.5E-99 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 1.5E-99 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 367 385 1.5E-99 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.5E-99 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 1.5E-99 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 403 421 1.5E-99 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 1.5E-99 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 312 334 1.5E-99 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 1.5E-99 T 12-10-2018 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_03090 e698dbf84d1494e691db12e4f81f2ced 435 SUPERFAMILY SSF103491 2 425 4.18E-124 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 SUPERFAMILY SSF51126 3 534 1.26E-31 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 SMART SM00710 360 382 110.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 SMART SM00710 411 433 3200.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 SMART SM00710 383 410 1000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 SMART SM00710 434 461 3100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 SMART SM00710 468 493 3500.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 SMART SM00710 337 359 2300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 Gene3D G3DSA:2.160.20.10 265 559 1.4E-17 T 12-10-2018 IPR012334 Pectin lyase fold TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 Pfam PF13229 Right handed beta helix region 354 516 3.1E-17 T 12-10-2018 IPR039448 Right handed beta helix domain TL08_00885 ac0781bfc270c619c14f31587cbbf415 577 Gene3D G3DSA:2.160.20.10 1 144 4.0E-14 T 12-10-2018 IPR012334 Pectin lyase fold TL08_07310 cff4ced28972da660883e9912516f17f 91 ProSitePatterns PS00605 ATP synthase c subunit signature. 53 74 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07310 cff4ced28972da660883e9912516f17f 91 Hamap MF_01396 ATP synthase subunit c [atpH]. 23 88 14.407 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07310 cff4ced28972da660883e9912516f17f 91 PRINTS PR00124 ATP synthase C subunit signature 46 61 1.4E-14 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07310 cff4ced28972da660883e9912516f17f 91 PRINTS PR00124 ATP synthase C subunit signature 63 88 1.4E-14 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07310 cff4ced28972da660883e9912516f17f 91 PRINTS PR00124 ATP synthase C subunit signature 25 44 1.4E-14 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07310 cff4ced28972da660883e9912516f17f 91 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 33 87 5.7E-19 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TL08_07310 cff4ced28972da660883e9912516f17f 91 Gene3D G3DSA:1.20.20.10 24 87 1.1E-20 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07310 cff4ced28972da660883e9912516f17f 91 Pfam PF00137 ATP synthase subunit C 26 86 5.7E-12 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TL08_07310 cff4ced28972da660883e9912516f17f 91 SUPERFAMILY SSF81333 27 87 1.05E-16 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TL08_08385 0ee5663e01419c96fb8f47e06b56622a 252 SUPERFAMILY SSF53067 8 251 6.89E-34 T 12-10-2018 TL08_08385 0ee5663e01419c96fb8f47e06b56622a 252 Gene3D G3DSA:3.30.420.40 112 251 1.6E-37 T 12-10-2018 TL08_08385 0ee5663e01419c96fb8f47e06b56622a 252 Gene3D G3DSA:3.30.420.40 4 106 1.1E-20 T 12-10-2018 TL08_08385 0ee5663e01419c96fb8f47e06b56622a 252 Pfam PF00480 ROK family 9 167 1.7E-15 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 Gene3D G3DSA:1.20.140.10 240 385 1.9E-49 T 12-10-2018 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 1.2E-47 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 Gene3D G3DSA:1.10.540.10 1 121 1.1E-39 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 SUPERFAMILY SSF47203 231 381 5.48E-50 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 SUPERFAMILY SSF56645 2 246 3.53E-77 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 2.8E-35 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 221 6.5E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TL08_22915 5c6295d8e1f325a480adbda33cf3ab67 385 Gene3D G3DSA:2.40.110.10 122 239 1.5E-35 T 12-10-2018 TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 Gene3D G3DSA:1.10.10.10 1 74 1.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 SUPERFAMILY SSF46785 4 87 1.9E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 SMART SM00866 96 233 8.8E-30 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.7E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.7E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 SUPERFAMILY SSF64288 62 239 5.65E-40 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 72 1.6E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 Gene3D G3DSA:3.40.1410.10 81 255 1.4E-37 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 Pfam PF07702 UTRA domain 97 232 1.7E-32 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_08625 41a4c4c27a4cdf92ff2f2df14b44f603 295 SMART SM00345 15 74 1.5E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 SMART SM00228 396 470 3.8E-9 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 SUPERFAMILY SSF50156 367 472 6.84E-18 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 Gene3D G3DSA:2.30.42.10 394 485 8.3E-19 T 12-10-2018 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 PRINTS PR00834 HtrA/DegQ protease family signature 344 361 5.1E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 PRINTS PR00834 HtrA/DegQ protease family signature 428 440 5.1E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 PRINTS PR00834 HtrA/DegQ protease family signature 242 262 5.1E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 PRINTS PR00834 HtrA/DegQ protease family signature 282 306 5.1E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 PRINTS PR00834 HtrA/DegQ protease family signature 322 339 5.1E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 PRINTS PR00834 HtrA/DegQ protease family signature 216 228 5.1E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 SUPERFAMILY SSF50494 181 402 4.15E-51 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 Pfam PF13180 PDZ domain 396 479 2.2E-12 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 Pfam PF13365 Trypsin-like peptidase domain 207 351 6.6E-33 T 12-10-2018 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 Gene3D G3DSA:2.40.10.10 178 271 1.4E-23 T 12-10-2018 TL08_04655 146dc16e7cae6079cdd6ee625a48cfb6 485 Gene3D G3DSA:2.40.10.10 273 393 1.9E-38 T 12-10-2018 TL08_26980 d209def8826206269dc4e6f6b3403170 511 SMART SM00382 287 481 4.8E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_26980 d209def8826206269dc4e6f6b3403170 511 SMART SM00382 40 228 4.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_26980 d209def8826206269dc4e6f6b3403170 511 Pfam PF00005 ABC transporter 279 432 1.4E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_26980 d209def8826206269dc4e6f6b3403170 511 Pfam PF00005 ABC transporter 31 180 4.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_26980 d209def8826206269dc4e6f6b3403170 511 SUPERFAMILY SSF52540 14 229 1.31E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26980 d209def8826206269dc4e6f6b3403170 511 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_26980 d209def8826206269dc4e6f6b3403170 511 Gene3D G3DSA:3.40.50.300 265 509 3.6E-44 T 12-10-2018 TL08_26980 d209def8826206269dc4e6f6b3403170 511 SUPERFAMILY SSF52540 275 493 1.29E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26980 d209def8826206269dc4e6f6b3403170 511 Gene3D G3DSA:3.40.50.300 13 242 1.6E-54 T 12-10-2018 TL08_01935 a5714e354db14b4eabca774795ce1280 364 SMART SM00382 31 214 5.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01935 a5714e354db14b4eabca774795ce1280 364 SUPERFAMILY SSF52540 11 244 1.36E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01935 a5714e354db14b4eabca774795ce1280 364 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_01935 a5714e354db14b4eabca774795ce1280 364 Gene3D G3DSA:2.40.50.140 285 344 5.6E-26 T 12-10-2018 TL08_01935 a5714e354db14b4eabca774795ce1280 364 SUPERFAMILY SSF50331 239 361 3.89E-23 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TL08_01935 a5714e354db14b4eabca774795ce1280 364 Gene3D G3DSA:2.40.50.940 225 354 5.6E-26 T 12-10-2018 TL08_01935 a5714e354db14b4eabca774795ce1280 364 Pfam PF00005 ABC transporter 23 164 7.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_01935 a5714e354db14b4eabca774795ce1280 364 Gene3D G3DSA:3.40.50.300 9 224 2.0E-60 T 12-10-2018 TL08_01935 a5714e354db14b4eabca774795ce1280 364 Pfam PF08402 TOBE domain 278 353 3.8E-5 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TL08_20395 a5714e354db14b4eabca774795ce1280 364 SMART SM00382 31 214 5.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_20395 a5714e354db14b4eabca774795ce1280 364 SUPERFAMILY SSF52540 11 244 1.36E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20395 a5714e354db14b4eabca774795ce1280 364 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_20395 a5714e354db14b4eabca774795ce1280 364 Gene3D G3DSA:2.40.50.140 285 344 5.6E-26 T 12-10-2018 TL08_20395 a5714e354db14b4eabca774795ce1280 364 SUPERFAMILY SSF50331 239 361 3.89E-23 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TL08_20395 a5714e354db14b4eabca774795ce1280 364 Gene3D G3DSA:2.40.50.940 225 354 5.6E-26 T 12-10-2018 TL08_20395 a5714e354db14b4eabca774795ce1280 364 Pfam PF00005 ABC transporter 23 164 7.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_20395 a5714e354db14b4eabca774795ce1280 364 Gene3D G3DSA:3.40.50.300 9 224 2.0E-60 T 12-10-2018 TL08_20395 a5714e354db14b4eabca774795ce1280 364 Pfam PF08402 TOBE domain 278 353 3.8E-5 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TL08_11095 1836813b490a9059758ae7a56fb30727 244 PIRSF PIRSF008292 1 235 4.9E-88 T 12-10-2018 IPR016538 Uncharacterised conserved protein UCP008292 TL08_11095 1836813b490a9059758ae7a56fb30727 244 Pfam PF00149 Calcineurin-like phosphoesterase 2 204 4.7E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_11095 1836813b490a9059758ae7a56fb30727 244 Gene3D G3DSA:3.60.21.10 2 238 1.1E-16 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_11095 1836813b490a9059758ae7a56fb30727 244 SUPERFAMILY SSF56300 2 225 1.44E-29 T 12-10-2018 TL08_26140 967e69220f9cdcc7665752acc2b64bdd 392 Pfam PF00155 Aminotransferase class I and II 37 384 1.6E-58 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_26140 967e69220f9cdcc7665752acc2b64bdd 392 SUPERFAMILY SSF53383 14 388 7.1E-97 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_26140 967e69220f9cdcc7665752acc2b64bdd 392 Gene3D G3DSA:3.40.640.10 8 392 5.5E-124 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_26140 967e69220f9cdcc7665752acc2b64bdd 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TL08_00340 32385866590f9787626b42604f4c2ca6 1254 PRINTS PR00723 Subtilisin serine protease family (S8) signature 233 252 1.1E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_00340 32385866590f9787626b42604f4c2ca6 1254 PRINTS PR00723 Subtilisin serine protease family (S8) signature 271 284 1.1E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_00340 32385866590f9787626b42604f4c2ca6 1254 PRINTS PR00723 Subtilisin serine protease family (S8) signature 446 462 1.1E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_00340 32385866590f9787626b42604f4c2ca6 1254 SUPERFAMILY SSF52743 214 506 3.01E-87 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_00340 32385866590f9787626b42604f4c2ca6 1254 Gene3D G3DSA:3.40.50.200 208 507 9.6E-98 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_00340 32385866590f9787626b42604f4c2ca6 1254 Pfam PF00082 Subtilase family 233 496 1.1E-57 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_00340 32385866590f9787626b42604f4c2ca6 1254 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 447 457 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_12210 436f65cab7b9c6d9caf731157389d48e 489 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 62 1.4E-9 T 12-10-2018 TL08_12210 436f65cab7b9c6d9caf731157389d48e 489 Gene3D G3DSA:3.90.660.50 90 403 1.2E-17 T 12-10-2018 TL08_12210 436f65cab7b9c6d9caf731157389d48e 489 SUPERFAMILY SSF51905 8 473 1.88E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_12210 436f65cab7b9c6d9caf731157389d48e 489 Gene3D G3DSA:3.50.50.60 10 287 1.2E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_04920 3ef0bb1b00f52c3ebd102678fb2d9f34 480 Gene3D G3DSA:1.20.150.30 95 225 5.7E-8 T 12-10-2018 TL08_04920 3ef0bb1b00f52c3ebd102678fb2d9f34 480 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 95 445 7.3E-116 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 TL08_04920 3ef0bb1b00f52c3ebd102678fb2d9f34 480 Pfam PF10103 Zincin-like metallopeptidase 95 443 3.7E-114 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 TL08_04920 3ef0bb1b00f52c3ebd102678fb2d9f34 480 SUPERFAMILY SSF55486 94 445 5.86E-109 T 12-10-2018 TL08_18260 15cc67c8d557a413822dd49bf8c1cb0d 263 Pfam PF14011 EspG family 9 252 3.4E-59 T 12-10-2018 IPR025734 EspG family TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 PRINTS PR01607 Apyrase family signature 549 568 6.6E-10 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 PRINTS PR01607 Apyrase family signature 250 267 6.6E-10 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 PRINTS PR01607 Apyrase family signature 455 478 6.6E-10 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 PRINTS PR01607 Apyrase family signature 43 61 6.6E-10 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 PRINTS PR01607 Apyrase family signature 270 293 6.6E-10 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 PRINTS PR01607 Apyrase family signature 318 338 6.6E-10 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 SUPERFAMILY SSF56300 43 377 3.8E-46 T 12-10-2018 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 SUPERFAMILY SSF55816 388 595 1.28E-29 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 Pfam PF02872 5'-nucleotidase, C-terminal domain 390 572 4.4E-28 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 Gene3D G3DSA:3.90.780.10 389 614 2.6E-46 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 Gene3D G3DSA:3.60.21.10 43 378 1.8E-61 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_05145 0af17b432315792d3e62ea105c5ec48f 618 ProSitePatterns PS00786 5'-nucleotidase signature 2. 146 157 - T 12-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TL08_26815 8a6e53d824e629a4317ae4b92400de58 821 Pfam PF00912 Transglycosylase 125 285 1.5E-45 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_26815 8a6e53d824e629a4317ae4b92400de58 821 Gene3D G3DSA:3.40.710.10 318 702 2.0E-92 T 12-10-2018 TL08_26815 8a6e53d824e629a4317ae4b92400de58 821 SUPERFAMILY SSF56601 267 692 6.84E-66 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_26815 8a6e53d824e629a4317ae4b92400de58 821 Pfam PF00905 Penicillin binding protein transpeptidase domain 376 639 2.2E-28 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TL08_26815 8a6e53d824e629a4317ae4b92400de58 821 Gene3D G3DSA:1.10.3810.10 116 300 1.3E-50 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_26815 8a6e53d824e629a4317ae4b92400de58 821 SUPERFAMILY SSF53955 103 301 7.31E-53 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 Gene3D G3DSA:3.30.70.580 99 256 7.6E-51 T 12-10-2018 TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 Pfam PF01479 S4 domain 36 78 9.6E-14 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 SMART SM00363 35 96 5.2E-12 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 101 259 4.0E-44 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 Pfam PF00849 RNA pseudouridylate synthase 96 228 1.1E-21 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 Gene3D G3DSA:3.10.290.10 30 93 1.5E-21 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 SUPERFAMILY SSF55174 32 87 8.05E-14 T 12-10-2018 TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 SUPERFAMILY SSF55120 88 270 5.4E-45 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 Gene3D G3DSA:3.30.70.1560 158 248 7.6E-51 T 12-10-2018 TL08_17955 ff4b7a526124b5c7fc5abcae1c6ff430 272 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 134 148 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 TL08_18540 c6d6de12727205e3f0c422ec026a3ac0 338 SUPERFAMILY SSF48576 38 337 2.08E-74 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_18540 c6d6de12727205e3f0c422ec026a3ac0 338 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TL08_18540 c6d6de12727205e3f0c422ec026a3ac0 338 Gene3D G3DSA:1.10.600.10 7 338 6.9E-102 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_18540 c6d6de12727205e3f0c422ec026a3ac0 338 Pfam PF00348 Polyprenyl synthetase 55 287 1.3E-52 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TL08_09290 65caa61109ee5a026d8183979f44b739 752 SMART SM00316 653 724 4.2E-15 T 12-10-2018 IPR022967 RNA-binding domain, S1 TL08_09290 65caa61109ee5a026d8183979f44b739 752 Pfam PF01138 3' exoribonuclease family, domain 1 352 484 8.6E-15 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_09290 65caa61109ee5a026d8183979f44b739 752 Pfam PF01138 3' exoribonuclease family, domain 1 21 152 8.7E-17 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_09290 65caa61109ee5a026d8183979f44b739 752 Gene3D G3DSA:3.30.230.70 261 581 3.3E-102 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_09290 65caa61109ee5a026d8183979f44b739 752 Gene3D G3DSA:2.40.50.140 582 706 5.8E-46 T 12-10-2018 TL08_09290 65caa61109ee5a026d8183979f44b739 752 SUPERFAMILY SSF54211 323 519 1.62E-42 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_09290 65caa61109ee5a026d8183979f44b739 752 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 18 722 7.0E-263 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TL08_09290 65caa61109ee5a026d8183979f44b739 752 SUPERFAMILY SSF46915 264 349 1.99E-15 T 12-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TL08_09290 65caa61109ee5a026d8183979f44b739 752 PIRSF PIRSF005499 8 752 1.7E-281 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TL08_09290 65caa61109ee5a026d8183979f44b739 752 SUPERFAMILY SSF50249 651 721 4.18E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_09290 65caa61109ee5a026d8183979f44b739 752 Gene3D G3DSA:3.30.230.70 5 250 1.5E-82 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_09290 65caa61109ee5a026d8183979f44b739 752 SMART SM00322 583 648 1.8E-10 T 12-10-2018 IPR004087 K Homology domain GO:0003676 TL08_09290 65caa61109ee5a026d8183979f44b739 752 Pfam PF00013 KH domain 587 644 5.2E-10 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TL08_09290 65caa61109ee5a026d8183979f44b739 752 SUPERFAMILY SSF55666 153 259 2.14E-26 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_09290 65caa61109ee5a026d8183979f44b739 752 Pfam PF00575 S1 RNA binding domain 652 721 2.0E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 TL08_09290 65caa61109ee5a026d8183979f44b739 752 Pfam PF03725 3' exoribonuclease family, domain 2 487 561 1.5E-5 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_09290 65caa61109ee5a026d8183979f44b739 752 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 268 347 1.4E-18 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TL08_09290 65caa61109ee5a026d8183979f44b739 752 SUPERFAMILY SSF54211 10 152 1.47E-45 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_09290 65caa61109ee5a026d8183979f44b739 752 SUPERFAMILY SSF54791 586 672 1.66E-17 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TL08_09290 65caa61109ee5a026d8183979f44b739 752 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 10 727 26.876 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TL08_09290 65caa61109ee5a026d8183979f44b739 752 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 7 723 0.0 T 12-10-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TL08_09290 65caa61109ee5a026d8183979f44b739 752 SUPERFAMILY SSF55666 478 577 4.74E-24 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_10815 056d877c1c77f4ce16baee75a5d37d70 324 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 19 319 6.6E-110 T 12-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 TL08_10815 056d877c1c77f4ce16baee75a5d37d70 324 Gene3D G3DSA:3.40.50.150 46 221 9.2E-55 T 12-10-2018 TL08_10815 056d877c1c77f4ce16baee75a5d37d70 324 Gene3D G3DSA:3.40.50.150 267 322 3.8E-7 T 12-10-2018 TL08_10815 056d877c1c77f4ce16baee75a5d37d70 324 SUPERFAMILY SSF53335 38 316 6.63E-12 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_10815 056d877c1c77f4ce16baee75a5d37d70 324 PIRSF PIRSF018005 2 323 1.6E-123 T 12-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 TL08_10815 056d877c1c77f4ce16baee75a5d37d70 324 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 6 322 54.47 T 12-10-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 TL08_10815 056d877c1c77f4ce16baee75a5d37d70 324 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 20 321 4.2E-109 T 12-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent TL08_05420 f79dd194b2b529459defc7e77e0ebf1c 509 Pfam PF07690 Major Facilitator Superfamily 24 410 8.0E-42 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_05420 f79dd194b2b529459defc7e77e0ebf1c 509 Gene3D G3DSA:1.20.1250.20 267 497 5.1E-9 T 12-10-2018 TL08_05420 f79dd194b2b529459defc7e77e0ebf1c 509 PRINTS PR01035 Tetracycline resistance protein signature 142 164 3.7E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_05420 f79dd194b2b529459defc7e77e0ebf1c 509 PRINTS PR01035 Tetracycline resistance protein signature 29 45 3.7E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_05420 f79dd194b2b529459defc7e77e0ebf1c 509 PRINTS PR01035 Tetracycline resistance protein signature 59 78 3.7E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_05420 f79dd194b2b529459defc7e77e0ebf1c 509 SUPERFAMILY SSF103473 7 500 1.44E-57 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_05420 f79dd194b2b529459defc7e77e0ebf1c 509 Gene3D G3DSA:1.20.1720.10 17 248 5.8E-36 T 12-10-2018 TL08_06355 55a125e344ab63119e43a8548880e854 397 SUPERFAMILY SSF55874 266 378 5.52E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_06355 55a125e344ab63119e43a8548880e854 397 Gene3D G3DSA:3.30.565.10 250 379 8.6E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_06355 55a125e344ab63119e43a8548880e854 397 Pfam PF07730 Histidine kinase 176 241 1.3E-10 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_21180 7b46782317d959909f532cf57bc602b1 427 SUPERFAMILY SSF55874 290 419 6.55E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_21180 7b46782317d959909f532cf57bc602b1 427 SMART SM00387 324 422 2.1E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_21180 7b46782317d959909f532cf57bc602b1 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 419 5.4E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_21180 7b46782317d959909f532cf57bc602b1 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 1.2E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_21180 7b46782317d959909f532cf57bc602b1 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 374 1.2E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_21180 7b46782317d959909f532cf57bc602b1 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 1.2E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_21180 7b46782317d959909f532cf57bc602b1 427 Gene3D G3DSA:3.30.565.10 284 421 5.6E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_21180 7b46782317d959909f532cf57bc602b1 427 PIRSF PIRSF037434 4 425 3.9E-65 T 12-10-2018 IPR017205 Signal transduction histidine kinase, ChrS TL08_21180 7b46782317d959909f532cf57bc602b1 427 Pfam PF07730 Histidine kinase 220 285 8.5E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 Pfam PF00365 Phosphofructokinase 2 296 4.6E-103 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 321 7.7E-151 T 12-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.2E-71 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.2E-71 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.2E-71 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.2E-71 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 2.2E-71 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.2E-71 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 2.2E-71 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.2E-71 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.2E-71 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 SUPERFAMILY SSF53784 1 333 4.05E-119 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 PIRSF PIRSF000532 1 338 1.7E-119 T 12-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 12-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 Gene3D G3DSA:3.40.50.450 3 322 2.0E-111 T 12-10-2018 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 Gene3D G3DSA:3.40.50.460 140 277 2.0E-111 T 12-10-2018 TL08_21655 f932d040d542b4fbfe4c685476f2beee 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 43.741 T 12-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TL08_16065 019a4f6c9e809d49f5664891994dc774 260 PIRSF PIRSF006648 7 252 1.4E-14 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_16065 019a4f6c9e809d49f5664891994dc774 260 Pfam PF01061 ABC-2 type transporter 14 213 3.8E-18 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_05175 7977f6125a68ad643b613bffb1e70b69 224 Pfam PF01814 Hemerythrin HHE cation binding domain 14 144 2.3E-14 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TL08_05175 7977f6125a68ad643b613bffb1e70b69 224 Gene3D G3DSA:1.20.120.520 6 161 5.5E-27 T 12-10-2018 TL08_06050 0ebedda32de343c57a8ce5ed60dba821 136 SUPERFAMILY SSF102462 4 135 2.56E-42 T 12-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TL08_06050 0ebedda32de343c57a8ce5ed60dba821 136 Gene3D G3DSA:3.40.1490.10 3 136 4.3E-52 T 12-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TL08_06050 0ebedda32de343c57a8ce5ed60dba821 136 Pfam PF09391 Protein of unknown function (DUF2000) 5 135 2.9E-42 T 12-10-2018 IPR018988 Protein of unknown function DUF2000 TL08_26600 09a5968f97e48d66cb83fb594ce6f8af 193 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 34.188 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TL08_26600 09a5968f97e48d66cb83fb594ce6f8af 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 4.5E-63 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TL08_26600 09a5968f97e48d66cb83fb594ce6f8af 193 SUPERFAMILY SSF51283 2 183 2.38E-56 T 12-10-2018 IPR036157 dUTPase-like superfamily TL08_26600 09a5968f97e48d66cb83fb594ce6f8af 193 Gene3D G3DSA:2.70.40.10 1 186 1.8E-58 T 12-10-2018 IPR036157 dUTPase-like superfamily TL08_26600 09a5968f97e48d66cb83fb594ce6f8af 193 Pfam PF00692 dUTPase 70 175 1.7E-9 T 12-10-2018 IPR029054 dUTPase-like TL08_00600 60dbca4a482c887a84d4473f0219f2b8 150 Gene3D G3DSA:3.40.220.10 1 148 6.4E-37 T 12-10-2018 TL08_00600 60dbca4a482c887a84d4473f0219f2b8 150 SMART SM00506 1 138 7.7E-7 T 12-10-2018 IPR002589 Macro domain TL08_00600 60dbca4a482c887a84d4473f0219f2b8 150 Pfam PF01661 Macro domain 10 136 2.6E-12 T 12-10-2018 IPR002589 Macro domain TL08_00600 60dbca4a482c887a84d4473f0219f2b8 150 SUPERFAMILY SSF52949 3 145 1.4E-24 T 12-10-2018 TL08_11145 26a976d2f79268d20d0e1578ef731820 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 8.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_11145 26a976d2f79268d20d0e1578ef731820 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 8.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_11145 26a976d2f79268d20d0e1578ef731820 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 8.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_11145 26a976d2f79268d20d0e1578ef731820 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 8.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_11145 26a976d2f79268d20d0e1578ef731820 255 SUPERFAMILY SSF55920 1 254 2.09E-71 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TL08_11145 26a976d2f79268d20d0e1578ef731820 255 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 35.651 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_11145 26a976d2f79268d20d0e1578ef731820 255 Pfam PF00557 Metallopeptidase family M24 12 246 1.2E-41 T 12-10-2018 IPR000994 Peptidase M24 TL08_11145 26a976d2f79268d20d0e1578ef731820 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 253 2.2E-75 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_11145 26a976d2f79268d20d0e1578ef731820 255 Gene3D G3DSA:3.90.230.10 1 255 1.1E-83 T 12-10-2018 TL08_17070 e7572c04fef3eb0a0c0687794ae339bb 284 Gene3D G3DSA:3.90.25.10 134 266 4.8E-78 T 12-10-2018 TL08_17070 e7572c04fef3eb0a0c0687794ae339bb 284 Pfam PF13460 NAD(P)H-binding 6 180 4.2E-29 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_17070 e7572c04fef3eb0a0c0687794ae339bb 284 Gene3D G3DSA:3.40.50.720 3 264 4.8E-78 T 12-10-2018 TL08_17070 e7572c04fef3eb0a0c0687794ae339bb 284 SUPERFAMILY SSF51735 2 275 8.01E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_17875 07fd26cee10c8c18d8d45923c6571770 277 Gene3D G3DSA:3.40.50.80 140 277 1.7E-41 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TL08_17875 07fd26cee10c8c18d8d45923c6571770 277 SUPERFAMILY SSF63380 10 141 2.4E-13 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TL08_17875 07fd26cee10c8c18d8d45923c6571770 277 Pfam PF04954 Siderophore-interacting protein 144 265 9.7E-34 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain TL08_17875 07fd26cee10c8c18d8d45923c6571770 277 Pfam PF08021 Siderophore-interacting FAD-binding domain 21 136 4.5E-34 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting TL08_17875 07fd26cee10c8c18d8d45923c6571770 277 Gene3D G3DSA:2.40.30.10 1 137 3.7E-46 T 12-10-2018 TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 168 184 - T 12-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 SUPERFAMILY SSF55347 173 337 1.44E-43 T 12-10-2018 TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 Gene3D G3DSA:3.40.50.720 32 355 7.3E-115 T 12-10-2018 TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 30 369 4.1E-112 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 Gene3D G3DSA:3.30.360.10 177 342 7.3E-115 T 12-10-2018 TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 31 155 1.3E-25 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 186 340 7.2E-19 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 SMART SM00859 31 163 9.4E-44 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 SUPERFAMILY SSF51735 30 197 7.14E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_18125 217eba9bd30cde9fa96345f7633d1f64 369 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 30 363 38.518 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_01165 dc0d97eed7a977e83d374a78398c3cc1 141 Gene3D G3DSA:2.20.25.10 1 45 5.1E-17 T 12-10-2018 TL08_01165 dc0d97eed7a977e83d374a78398c3cc1 141 Gene3D G3DSA:3.30.300.20 46 139 1.8E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_01165 dc0d97eed7a977e83d374a78398c3cc1 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 138 2.4E-48 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 TL08_01165 dc0d97eed7a977e83d374a78398c3cc1 141 SUPERFAMILY SSF82784 1 140 5.76E-40 T 12-10-2018 IPR036102 OsmC/Ohr superfamily TL08_01165 dc0d97eed7a977e83d374a78398c3cc1 141 Pfam PF02566 OsmC-like protein 41 137 1.6E-19 T 12-10-2018 IPR003718 OsmC/Ohr family TL08_12305 8b6e2a0eb990a48c0ec784a05040dc24 138 Pfam PF00571 CBS domain 5 58 4.9E-7 T 12-10-2018 IPR000644 CBS domain TL08_12305 8b6e2a0eb990a48c0ec784a05040dc24 138 Pfam PF00571 CBS domain 77 123 4.2E-7 T 12-10-2018 IPR000644 CBS domain TL08_12305 8b6e2a0eb990a48c0ec784a05040dc24 138 Gene3D G3DSA:3.10.580.10 1 127 5.2E-28 T 12-10-2018 TL08_12305 8b6e2a0eb990a48c0ec784a05040dc24 138 SUPERFAMILY SSF54631 3 123 2.4E-25 T 12-10-2018 TL08_12305 8b6e2a0eb990a48c0ec784a05040dc24 138 SMART SM00116 11 59 0.062 T 12-10-2018 IPR000644 CBS domain TL08_12305 8b6e2a0eb990a48c0ec784a05040dc24 138 SMART SM00116 77 124 5.2E-5 T 12-10-2018 IPR000644 CBS domain TL08_19480 f6a86d5acd1354d9178516dc70b80793 285 Gene3D G3DSA:3.40.50.300 13 277 1.9E-76 T 12-10-2018 TL08_19480 f6a86d5acd1354d9178516dc70b80793 285 SMART SM00382 41 239 3.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_19480 f6a86d5acd1354d9178516dc70b80793 285 SUPERFAMILY SSF52540 15 261 5.77E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19480 f6a86d5acd1354d9178516dc70b80793 285 Pfam PF00005 ABC transporter 33 189 2.7E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_19480 f6a86d5acd1354d9178516dc70b80793 285 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_26995 9d3c561576feb827dcf43ba0577e048a 724 SUPERFAMILY SSF82866 136 334 7.72E-31 T 12-10-2018 TL08_26995 9d3c561576feb827dcf43ba0577e048a 724 Gene3D G3DSA:1.20.1640.10 158 338 6.7E-10 T 12-10-2018 TL08_26995 9d3c561576feb827dcf43ba0577e048a 724 SUPERFAMILY SSF82866 462 689 8.24E-29 T 12-10-2018 TL08_26995 9d3c561576feb827dcf43ba0577e048a 724 Pfam PF03176 MMPL family 47 366 6.8E-45 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TL08_26995 9d3c561576feb827dcf43ba0577e048a 724 Pfam PF03176 MMPL family 396 692 8.1E-27 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TL08_25000 11f9effeeedc65050e8345baa361c2d1 222 Gene3D G3DSA:1.20.1440.130 28 211 5.5E-17 T 12-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 TL08_25000 11f9effeeedc65050e8345baa361c2d1 222 Pfam PF07884 Vitamin K epoxide reductase family 40 172 1.9E-29 T 12-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 TL08_25000 11f9effeeedc65050e8345baa361c2d1 222 SMART SM00756 35 176 8.4E-48 T 12-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 TL08_19570 8dfe9eb0b3202246e01da93215988a46 499 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 415 464 1.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_19570 8dfe9eb0b3202246e01da93215988a46 499 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 328 466 3.6E-30 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 TL08_19570 8dfe9eb0b3202246e01da93215988a46 499 SUPERFAMILY SSF56784 328 492 5.93E-44 T 12-10-2018 IPR036412 HAD-like superfamily TL08_19570 8dfe9eb0b3202246e01da93215988a46 499 Pfam PF13242 HAD-hyrolase-like 418 490 1.8E-16 T 12-10-2018 TL08_19570 8dfe9eb0b3202246e01da93215988a46 499 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 328 464 5.7E-34 T 12-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 TL08_19570 8dfe9eb0b3202246e01da93215988a46 499 Gene3D G3DSA:3.90.550.10 2 199 5.6E-27 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_19570 8dfe9eb0b3202246e01da93215988a46 499 Pfam PF00535 Glycosyl transferase family 2 5 118 6.7E-15 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_19570 8dfe9eb0b3202246e01da93215988a46 499 Gene3D G3DSA:3.40.50.1000 310 494 2.0E-48 T 12-10-2018 IPR023214 HAD superfamily TL08_19570 8dfe9eb0b3202246e01da93215988a46 499 SUPERFAMILY SSF53448 3 191 4.15E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_10105 91b5d58b9f4ad28093b4589755b98bbe 769 Gene3D G3DSA:3.40.50.300 193 370 1.1E-7 T 12-10-2018 TL08_10105 91b5d58b9f4ad28093b4589755b98bbe 769 Pfam PF05729 NACHT domain 241 387 7.1E-8 T 12-10-2018 IPR007111 NACHT nucleoside triphosphatase TL08_10105 91b5d58b9f4ad28093b4589755b98bbe 769 SUPERFAMILY SSF52540 225 360 1.47E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SUPERFAMILY SSF51126 36 358 9.58E-71 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 Pfam PF13229 Right handed beta helix region 632 818 2.9E-10 T 12-10-2018 IPR039448 Right handed beta helix domain TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 Gene3D G3DSA:2.160.20.10 534 891 2.9E-90 T 12-10-2018 IPR012334 Pectin lyase fold TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SUPERFAMILY SSF51126 538 878 2.03E-47 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 Gene3D G3DSA:2.160.20.10 35 358 6.8E-96 T 12-10-2018 IPR012334 Pectin lyase fold TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SMART SM00656 75 287 5.3E-16 T 12-10-2018 IPR002022 Pectate lyase TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SMART SM00710 748 782 3400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SMART SM00710 271 308 5100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SMART SM00710 719 741 170.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SMART SM00710 655 677 940.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SMART SM00710 135 166 780.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SMART SM00710 786 808 7100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 Gene3D G3DSA:2.60.120.260 404 514 8.9E-15 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 Pfam PF00544 Pectate lyase 77 281 5.8E-34 T 12-10-2018 IPR002022 Pectate lyase TL08_04085 fdb01f197d858fb7b68f57b270b64b99 898 SUPERFAMILY SSF49785 397 512 7.23E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_12155 af3e943aa9dc087ee51527b7edfd9bef 228 Gene3D G3DSA:3.40.50.300 9 228 2.5E-56 T 12-10-2018 TL08_12155 af3e943aa9dc087ee51527b7edfd9bef 228 SUPERFAMILY SSF52540 10 227 1.36E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12155 af3e943aa9dc087ee51527b7edfd9bef 228 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12155 af3e943aa9dc087ee51527b7edfd9bef 228 SMART SM00382 40 224 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12155 af3e943aa9dc087ee51527b7edfd9bef 228 Pfam PF00005 ABC transporter 31 177 2.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_18235 42beb960cd78339b71dc5fa644a25847 274 SUPERFAMILY SSF53098 36 175 3.04E-51 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_18235 42beb960cd78339b71dc5fa644a25847 274 Hamap MF_00042 Ribonuclease H [rnhA]. 34 183 31.916 T 12-10-2018 IPR022892 Ribonuclease HI GO:0004523 TL08_18235 42beb960cd78339b71dc5fa644a25847 274 Pfam PF00075 RNase H 36 174 2.1E-46 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 TL08_18235 42beb960cd78339b71dc5fa644a25847 274 Gene3D G3DSA:3.30.420.10 30 187 3.3E-55 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_25345 ed99b21274e769e99ab9b6b638ec5cad 273 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_25345 ed99b21274e769e99ab9b6b638ec5cad 273 SUPERFAMILY SSF52540 4 230 3.73E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25345 ed99b21274e769e99ab9b6b638ec5cad 273 Gene3D G3DSA:3.40.50.300 1 268 3.7E-68 T 12-10-2018 TL08_25345 ed99b21274e769e99ab9b6b638ec5cad 273 SMART SM00382 32 229 1.5E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_25345 ed99b21274e769e99ab9b6b638ec5cad 273 Pfam PF00005 ABC transporter 24 165 3.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_03140 6a0c8debb34ac47016cd58f9f00137db 176 Gene3D G3DSA:3.90.1030.10 3 125 5.7E-43 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03140 6a0c8debb34ac47016cd58f9f00137db 176 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 116 1.5E-38 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03140 6a0c8debb34ac47016cd58f9f00137db 176 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.527 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03140 6a0c8debb34ac47016cd58f9f00137db 176 SUPERFAMILY SSF64263 1 118 2.22E-45 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03140 6a0c8debb34ac47016cd58f9f00137db 176 Pfam PF01196 Ribosomal protein L17 20 116 3.5E-34 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_13070 849e6879a41ec3ea9ceea53beb4e4295 602 Gene3D G3DSA:3.40.190.10 11 285 3.3E-69 T 12-10-2018 TL08_13070 849e6879a41ec3ea9ceea53beb4e4295 602 SUPERFAMILY SSF53850 36 540 6.34E-122 T 12-10-2018 TL08_13070 849e6879a41ec3ea9ceea53beb4e4295 602 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 452 3.6E-85 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_13070 849e6879a41ec3ea9ceea53beb4e4295 602 PIRSF PIRSF002741 4 550 1.4E-91 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_13070 849e6879a41ec3ea9ceea53beb4e4295 602 Gene3D G3DSA:3.10.105.10 296 518 7.9E-49 T 12-10-2018 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 Pfam PF01084 Ribosomal protein S18 26 75 4.5E-24 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 Gene3D G3DSA:4.10.640.10 2 83 6.5E-26 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 TIGRFAM TIGR00165 S18: ribosomal protein bS18 14 77 1.8E-23 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 77 1.0E-17 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 2.1E-17 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 2.1E-17 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 2.1E-17 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 2.1E-17 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 SUPERFAMILY SSF46911 9 79 8.24E-25 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17735 564607235d61fe3b0208b0114c7dc959 83 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 11 80 19.662 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02250 a09ee8e2741d1c89b1dec85b2687e4c9 307 SUPERFAMILY SSF51735 118 248 5.47E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_02250 a09ee8e2741d1c89b1dec85b2687e4c9 307 SUPERFAMILY SSF50129 4 150 5.17E-34 T 12-10-2018 IPR011032 GroES-like superfamily TL08_02250 a09ee8e2741d1c89b1dec85b2687e4c9 307 Pfam PF13602 Zinc-binding dehydrogenase 191 304 4.6E-13 T 12-10-2018 TL08_02250 a09ee8e2741d1c89b1dec85b2687e4c9 307 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 92 4.5E-8 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_02250 a09ee8e2741d1c89b1dec85b2687e4c9 307 Gene3D G3DSA:3.40.50.720 129 255 3.6E-70 T 12-10-2018 TL08_02250 a09ee8e2741d1c89b1dec85b2687e4c9 307 Gene3D G3DSA:3.90.180.10 9 303 3.6E-70 T 12-10-2018 TL08_02250 a09ee8e2741d1c89b1dec85b2687e4c9 307 SMART SM00829 11 304 1.2E-12 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_00410 f4b22094ce3dec4d2181329bcf3fd46a 471 SMART SM00387 280 390 2.4E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_00410 f4b22094ce3dec4d2181329bcf3fd46a 471 Gene3D G3DSA:3.30.565.10 244 389 1.7E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_00410 f4b22094ce3dec4d2181329bcf3fd46a 471 Pfam PF06580 Histidine kinase 190 266 2.7E-24 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 TL08_00410 f4b22094ce3dec4d2181329bcf3fd46a 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 288 387 6.3E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_00410 f4b22094ce3dec4d2181329bcf3fd46a 471 SUPERFAMILY SSF55874 258 387 2.62E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_19675 f0c96a56c18e37653b2c93d855316e23 309 SUPERFAMILY SSF161098 89 291 2.13E-15 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19675 f0c96a56c18e37653b2c93d855316e23 309 Gene3D G3DSA:1.10.3720.10 85 299 1.9E-21 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19675 f0c96a56c18e37653b2c93d855316e23 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 305 4.2E-37 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_14965 dd918055d415b8d63320351100872ee9 176 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 41 169 8.8E-7 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 Gene3D G3DSA:2.40.340.10 347 414 4.5E-129 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 Pfam PF03454 MoeA C-terminal region (domain IV) 356 419 2.1E-14 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 SMART SM00852 200 336 3.3E-39 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 196 332 3.4E-32 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 SUPERFAMILY SSF63867 355 421 1.44E-15 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 Pfam PF03453 MoeA N-terminal region (domain I and II) 24 187 8.0E-42 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 SUPERFAMILY SSF53218 195 340 1.11E-39 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 Gene3D G3DSA:3.40.980.10 195 346 4.5E-129 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 SUPERFAMILY SSF63882 22 196 1.44E-49 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 Gene3D G3DSA:3.90.105.10 42 194 4.5E-129 T 12-10-2018 TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 Gene3D G3DSA:2.170.190.11 65 161 4.5E-129 T 12-10-2018 TL08_25425 e8efb859e4f4aba515f47f03edfe1431 433 Pfam PF00994 Probable molybdopterin binding domain 201 334 1.2E-24 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_16295 ba6f3658a7ab6deac425786fe1cf8bdf 381 SUPERFAMILY SSF53383 66 377 2.16E-36 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_16295 ba6f3658a7ab6deac425786fe1cf8bdf 381 TIGRFAM TIGR04462 endura_MppP: enduracididine biosynthesis enzyme MppP 89 377 1.4E-146 T 12-10-2018 IPR031020 Enduracididine biosynthesis enzyme MppP TL08_16295 ba6f3658a7ab6deac425786fe1cf8bdf 381 Pfam PF00155 Aminotransferase class I and II 72 370 2.2E-16 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_16295 ba6f3658a7ab6deac425786fe1cf8bdf 381 Gene3D G3DSA:3.90.1150.10 28 367 1.1E-116 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_16295 ba6f3658a7ab6deac425786fe1cf8bdf 381 Gene3D G3DSA:3.40.640.10 36 270 1.1E-116 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_10210 52cf25add997857816d6e74ef2aaa9b0 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_10210 52cf25add997857816d6e74ef2aaa9b0 237 PIRSF PIRSF039137 1 237 5.6E-110 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 TL08_10210 52cf25add997857816d6e74ef2aaa9b0 237 Pfam PF00005 ABC transporter 19 164 2.3E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_10210 52cf25add997857816d6e74ef2aaa9b0 237 Gene3D G3DSA:3.40.50.300 1 237 8.6E-68 T 12-10-2018 TL08_10210 52cf25add997857816d6e74ef2aaa9b0 237 SMART SM00382 28 215 2.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_10210 52cf25add997857816d6e74ef2aaa9b0 237 SUPERFAMILY SSF52540 3 234 1.2E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23775 ed0205573132b584be57e75558600c70 150 SUPERFAMILY SSF110857 3 120 1.31E-16 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily TL08_23775 ed0205573132b584be57e75558600c70 150 Gene3D G3DSA:3.10.490.10 2 147 7.3E-39 T 12-10-2018 TL08_23775 ed0205573132b584be57e75558600c70 150 Pfam PF13772 AIG2-like family 59 137 1.3E-21 T 12-10-2018 TL08_17605 35c26b5389c6b6869253567da37cad83 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 70 113 1.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_17605 35c26b5389c6b6869253567da37cad83 241 Gene3D G3DSA:1.10.357.10 53 240 6.1E-24 T 12-10-2018 TL08_17605 35c26b5389c6b6869253567da37cad83 241 SUPERFAMILY SSF46689 59 128 3.89E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_02695 123aef91ab1756ab3d13accfc535cbf8 637 Gene3D G3DSA:3.40.920.10 26 232 2.4E-15 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TL08_02695 123aef91ab1756ab3d13accfc535cbf8 637 Gene3D G3DSA:3.40.50.970 240 441 7.9E-63 T 12-10-2018 TL08_02695 123aef91ab1756ab3d13accfc535cbf8 637 SUPERFAMILY SSF52518 250 516 3.98E-60 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_02695 123aef91ab1756ab3d13accfc535cbf8 637 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 276 493 3.6E-53 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TL08_02695 123aef91ab1756ab3d13accfc535cbf8 637 SUPERFAMILY SSF52922 533 633 2.69E-12 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_02695 123aef91ab1756ab3d13accfc535cbf8 637 Gene3D G3DSA:3.40.50.920 529 633 1.5E-17 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_02695 123aef91ab1756ab3d13accfc535cbf8 637 SUPERFAMILY SSF53323 32 243 6.67E-17 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TL08_02695 123aef91ab1756ab3d13accfc535cbf8 637 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 38 226 3.9E-26 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TL08_02695 123aef91ab1756ab3d13accfc535cbf8 637 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 30 626 1.6E-197 T 12-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 TL08_11610 8a1a84a80a2ccc2fe9be3cbc0fcd4905 300 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 16 299 40.926 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 TL08_11610 8a1a84a80a2ccc2fe9be3cbc0fcd4905 300 PIRSF PIRSF005052 16 300 1.3E-110 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 TL08_11610 8a1a84a80a2ccc2fe9be3cbc0fcd4905 300 Gene3D G3DSA:3.40.50.300 17 181 2.5E-5 T 12-10-2018 TL08_11610 8a1a84a80a2ccc2fe9be3cbc0fcd4905 300 SUPERFAMILY SSF52540 20 170 2.54E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11610 8a1a84a80a2ccc2fe9be3cbc0fcd4905 300 Pfam PF03668 P-loop ATPase protein family 16 300 4.0E-109 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 TL08_11580 b54ff53bf863de1b7cb50212e772ddbe 212 PIRSF PIRSF000498 1 208 5.7E-72 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_11580 b54ff53bf863de1b7cb50212e772ddbe 212 Gene3D G3DSA:2.40.30.20 1 88 1.6E-27 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_11580 b54ff53bf863de1b7cb50212e772ddbe 212 Pfam PF00677 Lumazine binding domain 3 86 3.6E-22 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_11580 b54ff53bf863de1b7cb50212e772ddbe 212 Pfam PF00677 Lumazine binding domain 99 183 2.2E-26 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_11580 b54ff53bf863de1b7cb50212e772ddbe 212 Gene3D G3DSA:2.40.30.20 101 199 9.5E-36 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_11580 b54ff53bf863de1b7cb50212e772ddbe 212 SUPERFAMILY SSF63380 2 87 1.62E-24 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TL08_11580 b54ff53bf863de1b7cb50212e772ddbe 212 SUPERFAMILY SSF63380 92 193 1.62E-33 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TL08_11580 b54ff53bf863de1b7cb50212e772ddbe 212 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 192 3.5E-64 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_07865 0e34cd644a876c16ee4e7e1a38a8c058 320 Pfam PF00924 Mechanosensitive ion channel 109 308 2.5E-39 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TL08_07865 0e34cd644a876c16ee4e7e1a38a8c058 320 Gene3D G3DSA:3.30.70.100 218 307 4.4E-22 T 12-10-2018 TL08_07865 0e34cd644a876c16ee4e7e1a38a8c058 320 Gene3D G3DSA:2.30.30.60 167 216 1.7E-18 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TL08_07865 0e34cd644a876c16ee4e7e1a38a8c058 320 SUPERFAMILY SSF82861 95 150 8.89E-10 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TL08_07865 0e34cd644a876c16ee4e7e1a38a8c058 320 SUPERFAMILY SSF82689 217 313 1.83E-14 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TL08_07865 0e34cd644a876c16ee4e7e1a38a8c058 320 SUPERFAMILY SSF50182 151 209 1.28E-11 T 12-10-2018 IPR010920 LSM domain superfamily TL08_18205 138a574607dc1071eb934e966b920de7 950 Gene3D G3DSA:1.20.1580.10 91 503 3.5E-262 T 12-10-2018 TL08_18205 138a574607dc1071eb934e966b920de7 950 Gene3D G3DSA:3.40.50.300 6 606 3.5E-262 T 12-10-2018 TL08_18205 138a574607dc1071eb934e966b920de7 950 SUPERFAMILY SSF52540 10 580 2.45E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18205 138a574607dc1071eb934e966b920de7 950 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 950 22.662 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 TL08_18205 138a574607dc1071eb934e966b920de7 950 Gene3D G3DSA:3.30.190.20 131 248 3.5E-262 T 12-10-2018 TL08_18205 138a574607dc1071eb934e966b920de7 950 Gene3D G3DSA:3.40.50.300 627 946 1.3E-142 T 12-10-2018 TL08_18205 138a574607dc1071eb934e966b920de7 950 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_18205 138a574607dc1071eb934e966b920de7 950 Gene3D G3DSA:1.10.8.280 292 409 3.5E-262 T 12-10-2018 TL08_18205 138a574607dc1071eb934e966b920de7 950 Gene3D G3DSA:1.20.1580.10 702 840 1.3E-142 T 12-10-2018 TL08_18205 138a574607dc1071eb934e966b920de7 950 Pfam PF00005 ABC transporter 635 870 5.7E-9 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_18205 138a574607dc1071eb934e966b920de7 950 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 934 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 TL08_18205 138a574607dc1071eb934e966b920de7 950 SUPERFAMILY SSF52540 626 924 7.34E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18205 138a574607dc1071eb934e966b920de7 950 ProSitePatterns PS00211 ABC transporters family signature. 840 854 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_21415 44764bbea887307325bfe2a171591931 573 SUPERFAMILY SSF56014 426 572 1.57E-34 T 12-10-2018 TL08_21415 44764bbea887307325bfe2a171591931 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 107 168 6.2E-20 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_21415 44764bbea887307325bfe2a171591931 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 353 417 1.1E-13 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_21415 44764bbea887307325bfe2a171591931 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 433 567 1.1E-7 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_21415 44764bbea887307325bfe2a171591931 573 SUPERFAMILY SSF55124 347 423 1.23E-18 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_21415 44764bbea887307325bfe2a171591931 573 Gene3D G3DSA:3.30.413.10 170 348 2.9E-125 T 12-10-2018 TL08_21415 44764bbea887307325bfe2a171591931 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 178 331 6.7E-38 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_21415 44764bbea887307325bfe2a171591931 573 Gene3D G3DSA:3.30.413.10 427 573 7.1E-41 T 12-10-2018 TL08_21415 44764bbea887307325bfe2a171591931 573 SUPERFAMILY SSF56014 176 357 2.22E-46 T 12-10-2018 TL08_21415 44764bbea887307325bfe2a171591931 573 PRINTS PR00397 Sirohaem Fe-binding site signature 430 448 1.4E-9 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_21415 44764bbea887307325bfe2a171591931 573 PRINTS PR00397 Sirohaem Fe-binding site signature 479 497 1.4E-9 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_21415 44764bbea887307325bfe2a171591931 573 SUPERFAMILY SSF55124 27 177 3.76E-39 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_21415 44764bbea887307325bfe2a171591931 573 Gene3D G3DSA:3.90.480.20 40 415 2.9E-125 T 12-10-2018 TL08_21415 44764bbea887307325bfe2a171591931 573 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 479 495 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 376 4.4E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 Gene3D G3DSA:1.10.287.130 107 224 3.1E-28 T 12-10-2018 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 Gene3D G3DSA:3.30.565.10 228 378 1.1E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 SMART SM00388 157 224 1.4E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 Pfam PF00672 HAMP domain 104 152 1.9E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1 12 7.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 332 7.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 7.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 356 7.3E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 SUPERFAMILY SSF47384 140 222 8.83E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 223 2.4E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 SMART SM00387 267 378 3.1E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 SUPERFAMILY SSF55874 231 375 1.31E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 SUPERFAMILY SSF158472 104 153 1.7E-7 T 12-10-2018 TL08_08460 04071c69f8b8ff9f3cdacbbe140434f9 378 SMART SM00304 103 156 1.2E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_19175 69637a20df6fb67ea408183d24dc9297 465 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 12 365 2.8E-113 T 12-10-2018 IPR010839 Acyclic terpene utilisation TL08_21910 042edb4c7d67f8c8d7754a63a6ecc61c 176 Pfam PF06271 RDD family 98 169 2.2E-5 T 12-10-2018 IPR010432 RDD TL08_21910 042edb4c7d67f8c8d7754a63a6ecc61c 176 PIRSF PIRSF021697 21 175 1.2E-44 T 12-10-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane TL08_18600 b6217e053ca60f0b650dd5e4380e1124 249 SUPERFAMILY SSF53474 2 246 1.02E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18600 b6217e053ca60f0b650dd5e4380e1124 249 Gene3D G3DSA:3.40.50.1820 1 247 3.8E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18600 b6217e053ca60f0b650dd5e4380e1124 249 Pfam PF12697 Alpha/beta hydrolase family 3 235 7.9E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_13395 e82af998949f640d5794165bf3711248 449 PIRSF PIRSF000136 35 265 3.5E-42 T 12-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 TL08_13395 e82af998949f640d5794165bf3711248 449 PIRSF PIRSF000136 315 448 2.1E-9 T 12-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 TL08_13395 e82af998949f640d5794165bf3711248 449 Pfam PF01565 FAD binding domain 54 180 1.7E-21 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TL08_13395 e82af998949f640d5794165bf3711248 449 Gene3D G3DSA:3.30.43.10 37 101 1.0E-21 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TL08_13395 e82af998949f640d5794165bf3711248 449 SUPERFAMILY SSF56176 33 209 1.18E-38 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_13395 e82af998949f640d5794165bf3711248 449 Gene3D G3DSA:3.30.70.2520 316 409 1.1E-32 T 12-10-2018 TL08_13395 e82af998949f640d5794165bf3711248 449 Pfam PF04030 D-arabinono-1,4-lactone oxidase 318 442 1.3E-19 T 12-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 TL08_13395 e82af998949f640d5794165bf3711248 449 Gene3D G3DSA:3.30.70.2530 212 297 4.1E-78 T 12-10-2018 TL08_13395 e82af998949f640d5794165bf3711248 449 Gene3D G3DSA:3.30.465.10 107 314 4.1E-78 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TL08_13395 e82af998949f640d5794165bf3711248 449 Gene3D G3DSA:1.10.45.10 410 444 5.5E-7 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TL08_22825 0007f175a11b48777e562dbd0c21897a 505 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 13 489 91.586 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_22825 0007f175a11b48777e562dbd0c21897a 505 Pfam PF01425 Amidase 26 476 2.2E-158 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_22825 0007f175a11b48777e562dbd0c21897a 505 SUPERFAMILY SSF75304 4 485 8.76E-159 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_22825 0007f175a11b48777e562dbd0c21897a 505 ProSitePatterns PS00571 Amidases signature. 155 186 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TL08_22825 0007f175a11b48777e562dbd0c21897a 505 Gene3D G3DSA:3.90.1300.10 5 495 2.1E-186 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_22825 0007f175a11b48777e562dbd0c21897a 505 PIRSF PIRSF001221 4 451 1.7E-43 T 12-10-2018 TL08_22825 0007f175a11b48777e562dbd0c21897a 505 PIRSF PIRSF001221 454 489 2.4 T 12-10-2018 TL08_22825 0007f175a11b48777e562dbd0c21897a 505 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 15 486 3.1E-187 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_06685 d78317451d88ebc0d8a8ae2dc7e1619e 458 Gene3D G3DSA:3.40.640.10 13 260 4.0E-137 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_06685 d78317451d88ebc0d8a8ae2dc7e1619e 458 Pfam PF00266 Aminotransferase class-V 3 379 6.3E-59 T 12-10-2018 IPR000192 Aminotransferase class V domain TL08_06685 d78317451d88ebc0d8a8ae2dc7e1619e 458 SUPERFAMILY SSF53383 2 388 3.72E-90 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_06685 d78317451d88ebc0d8a8ae2dc7e1619e 458 Gene3D G3DSA:3.90.1150.10 3 379 4.0E-137 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_06685 d78317451d88ebc0d8a8ae2dc7e1619e 458 PIRSF PIRSF005572 1 393 7.5E-106 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TL08_23705 cd20969b3d8d1e881b314afcfcb0ea1a 369 Gene3D G3DSA:3.40.190.10 166 277 2.8E-48 T 12-10-2018 TL08_23705 cd20969b3d8d1e881b314afcfcb0ea1a 369 Pfam PF13343 Bacterial extracellular solute-binding protein 117 330 2.4E-23 T 12-10-2018 TL08_23705 cd20969b3d8d1e881b314afcfcb0ea1a 369 SUPERFAMILY SSF53850 59 361 4.8E-49 T 12-10-2018 TL08_23705 cd20969b3d8d1e881b314afcfcb0ea1a 369 Gene3D G3DSA:3.40.190.10 66 328 2.8E-48 T 12-10-2018 TL08_11030 fa885fe568c47cd19becdd0dde4a6501 392 Pfam PF00108 Thiolase, N-terminal domain 5 262 1.5E-57 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TL08_11030 fa885fe568c47cd19becdd0dde4a6501 392 SUPERFAMILY SSF53901 270 391 4.78E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_11030 fa885fe568c47cd19becdd0dde4a6501 392 Gene3D G3DSA:3.40.47.10 127 386 3.5E-130 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_11030 fa885fe568c47cd19becdd0dde4a6501 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TL08_11030 fa885fe568c47cd19becdd0dde4a6501 392 PIRSF PIRSF000429 1 392 5.9E-113 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_11030 fa885fe568c47cd19becdd0dde4a6501 392 SUPERFAMILY SSF53901 1 266 2.51E-68 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_11030 fa885fe568c47cd19becdd0dde4a6501 392 Gene3D G3DSA:3.40.47.10 6 275 3.5E-130 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_11030 fa885fe568c47cd19becdd0dde4a6501 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 2.0E-128 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_11030 fa885fe568c47cd19becdd0dde4a6501 392 Pfam PF02803 Thiolase, C-terminal domain 270 391 1.8E-39 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TL08_09810 2d4fce9a5a57718d6f59bf7e40ebdc10 241 Pfam PF01553 Acyltransferase 46 168 1.8E-19 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_09810 2d4fce9a5a57718d6f59bf7e40ebdc10 241 SMART SM00563 61 171 4.9E-29 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_09810 2d4fce9a5a57718d6f59bf7e40ebdc10 241 SUPERFAMILY SSF69593 34 229 2.48E-34 T 12-10-2018 TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 39.371 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 44 284 1.6E-88 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 SUPERFAMILY SSF55920 4 284 1.02E-88 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 5.2E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 5.2E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 5.2E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 5.2E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 Gene3D G3DSA:3.90.230.10 3 285 9.1E-114 T 12-10-2018 TL08_08965 b8c120599f3b594728f919dbb7d5be61 285 Pfam PF00557 Metallopeptidase family M24 48 276 3.6E-50 T 12-10-2018 IPR000994 Peptidase M24 TL08_18020 d2eaf130c57d5affd806c1f530298bd8 569 Gene3D G3DSA:3.40.50.880 296 551 1.5E-99 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_18020 d2eaf130c57d5affd806c1f530298bd8 569 Gene3D G3DSA:3.40.50.300 2 295 8.7E-133 T 12-10-2018 TL08_18020 d2eaf130c57d5affd806c1f530298bd8 569 Pfam PF00117 Glutamine amidotransferase class-I 311 542 1.9E-47 T 12-10-2018 IPR017926 Glutamine amidotransferase TL08_18020 d2eaf130c57d5affd806c1f530298bd8 569 TIGRFAM TIGR00337 PyrG: CTP synthase 6 543 1.0E-227 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TL08_18020 d2eaf130c57d5affd806c1f530298bd8 569 SUPERFAMILY SSF52317 299 549 1.57E-74 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_18020 d2eaf130c57d5affd806c1f530298bd8 569 Pfam PF06418 CTP synthase N-terminus 8 276 1.3E-121 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TL08_18020 d2eaf130c57d5affd806c1f530298bd8 569 SUPERFAMILY SSF52540 8 276 6.45E-118 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18020 d2eaf130c57d5affd806c1f530298bd8 569 Hamap MF_01227 CTP synthase [pyrG]. 7 548 50.186 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TL08_09230 2556cff08f42706250908a04ed314e44 284 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 220 274 2.2E-15 T 12-10-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_09230 2556cff08f42706250908a04ed314e44 284 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 11 163 2.5E-49 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TL08_09230 2556cff08f42706250908a04ed314e44 284 SUPERFAMILY SSF88697 220 274 7.95E-10 T 12-10-2018 IPR015947 PUA-like superfamily TL08_09230 2556cff08f42706250908a04ed314e44 284 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 200 3.1E-61 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_09230 2556cff08f42706250908a04ed314e44 284 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 272 14.228 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_09230 2556cff08f42706250908a04ed314e44 284 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 164 204 2.8E-11 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TL08_09230 2556cff08f42706250908a04ed314e44 284 Gene3D G3DSA:3.30.2350.10 1 211 9.4E-80 T 12-10-2018 TL08_09230 2556cff08f42706250908a04ed314e44 284 SUPERFAMILY SSF55120 1 206 5.18E-65 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_09230 2556cff08f42706250908a04ed314e44 284 Gene3D G3DSA:2.30.130.10 212 274 8.2E-16 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 TL08_16315 0f63ec2e1947f3b8e8be78864c04cf82 457 Pfam PF05977 Transmembrane secretion effector 39 437 8.4E-24 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_16315 0f63ec2e1947f3b8e8be78864c04cf82 457 SUPERFAMILY SSF103473 39 442 6.8E-42 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_16315 0f63ec2e1947f3b8e8be78864c04cf82 457 Gene3D G3DSA:1.20.1250.20 36 436 8.4E-37 T 12-10-2018 TL08_03920 debde21ab01c330670a96fe88fa0f9ce 505 Gene3D G3DSA:2.60.40.1180 13 502 1.1E-219 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_03920 debde21ab01c330670a96fe88fa0f9ce 505 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 297 497 1.1E-42 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 TL08_03920 debde21ab01c330670a96fe88fa0f9ce 505 SMART SM00813 297 497 3.7E-80 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 TL08_03920 debde21ab01c330670a96fe88fa0f9ce 505 Gene3D G3DSA:3.20.20.80 24 387 1.1E-219 T 12-10-2018 TL08_03920 debde21ab01c330670a96fe88fa0f9ce 505 SUPERFAMILY SSF51445 24 386 1.83E-110 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_03920 debde21ab01c330670a96fe88fa0f9ce 505 SUPERFAMILY SSF51011 375 504 1.65E-35 T 12-10-2018 TL08_25385 f8f4835cea3c3cf0b310a2286102f6de 224 Gene3D G3DSA:3.20.20.380 5 224 1.2E-48 T 12-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 TL08_25385 f8f4835cea3c3cf0b310a2286102f6de 224 SUPERFAMILY SSF110395 5 220 3.4E-43 T 12-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 TL08_25385 f8f4835cea3c3cf0b310a2286102f6de 224 Pfam PF03932 CutC family 6 198 5.5E-32 T 12-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 TL08_00825 0815f21002831e5e697205ca0fd9951d 325 Gene3D G3DSA:3.40.50.720 4 171 6.3E-88 T 12-10-2018 TL08_00825 0815f21002831e5e697205ca0fd9951d 325 SUPERFAMILY SSF51735 4 167 1.42E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_00825 0815f21002831e5e697205ca0fd9951d 325 Pfam PF02153 Prephenate dehydrogenase 31 244 1.4E-42 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TL08_00825 0815f21002831e5e697205ca0fd9951d 325 SUPERFAMILY SSF48179 172 263 2.49E-20 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_00825 0815f21002831e5e697205ca0fd9951d 325 Gene3D G3DSA:1.10.3660.10 172 277 6.3E-88 T 12-10-2018 TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 Gene3D G3DSA:3.40.50.720 4 228 6.7E-50 T 12-10-2018 TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 Pfam PF00106 short chain dehydrogenase 7 185 1.3E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 SUPERFAMILY SSF51735 6 211 6.58E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.2E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.2E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.2E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.2E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 209 1.2E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.2E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 173 0.0045 T 12-10-2018 TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 7.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 7.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19590 ae3ec9eb335f91e9011865667dc24238 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 7.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00925 44b9e51f170465f254172cc9b7523b77 317 Pfam PF00248 Aldo/keto reductase family 7 304 4.2E-63 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_00925 44b9e51f170465f254172cc9b7523b77 317 Gene3D G3DSA:3.20.20.100 2 317 1.2E-96 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_00925 44b9e51f170465f254172cc9b7523b77 317 PRINTS PR00069 Aldo-keto reductase signature 126 143 4.4E-8 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_00925 44b9e51f170465f254172cc9b7523b77 317 PRINTS PR00069 Aldo-keto reductase signature 95 113 4.4E-8 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_00925 44b9e51f170465f254172cc9b7523b77 317 SUPERFAMILY SSF51430 6 313 3.27E-79 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_00925 44b9e51f170465f254172cc9b7523b77 317 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TL08_18155 2690b868630af8f2c4d3d93245052546 861 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 111 860 1.8E-158 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TL08_18155 2690b868630af8f2c4d3d93245052546 861 SUPERFAMILY SSF54991 765 860 1.96E-26 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TL08_18155 2690b868630af8f2c4d3d93245052546 861 SUPERFAMILY SSF50249 109 233 5.71E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_18155 2690b868630af8f2c4d3d93245052546 861 SMART SM00896 767 860 3.0E-41 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TL08_18155 2690b868630af8f2c4d3d93245052546 861 Pfam PF03484 tRNA synthetase B5 domain 448 514 5.8E-12 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TL08_18155 2690b868630af8f2c4d3d93245052546 861 Gene3D G3DSA:3.30.56.10 441 518 1.3E-14 T 12-10-2018 TL08_18155 2690b868630af8f2c4d3d93245052546 861 Pfam PF01588 Putative tRNA binding domain 110 181 2.6E-9 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TL08_18155 2690b868630af8f2c4d3d93245052546 861 SUPERFAMILY SSF55681 510 755 2.44E-39 T 12-10-2018 TL08_18155 2690b868630af8f2c4d3d93245052546 861 Pfam PF03147 Ferredoxin-fold anticodon binding domain 767 860 8.2E-25 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TL08_18155 2690b868630af8f2c4d3d93245052546 861 SMART SM00873 252 425 2.7E-72 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TL08_18155 2690b868630af8f2c4d3d93245052546 861 Gene3D G3DSA:3.30.70.380 768 861 2.4E-27 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TL08_18155 2690b868630af8f2c4d3d93245052546 861 SMART SM00874 441 514 1.0E-17 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TL08_18155 2690b868630af8f2c4d3d93245052546 861 SUPERFAMILY SSF56037 239 435 1.6E-62 T 12-10-2018 TL08_18155 2690b868630af8f2c4d3d93245052546 861 Pfam PF03483 B3/4 domain 252 422 8.1E-60 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TL08_18155 2690b868630af8f2c4d3d93245052546 861 Gene3D G3DSA:3.50.40.10 239 434 8.6E-70 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 TL08_18155 2690b868630af8f2c4d3d93245052546 861 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 854 38.448 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TL08_18155 2690b868630af8f2c4d3d93245052546 861 Gene3D G3DSA:3.30.930.10 530 756 1.3E-53 T 12-10-2018 TL08_18155 2690b868630af8f2c4d3d93245052546 861 SUPERFAMILY SSF46955 443 518 8.7E-12 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_16825 4023df30b92aafa0051c76ee6c66e5ae 268 SUPERFAMILY SSF51735 6 217 7.82E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16825 4023df30b92aafa0051c76ee6c66e5ae 268 Gene3D G3DSA:3.40.50.720 3 257 1.6E-42 T 12-10-2018 TL08_16825 4023df30b92aafa0051c76ee6c66e5ae 268 Pfam PF13460 NAD(P)H-binding 9 182 9.2E-21 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_23525 19533178b5b1d9768ce15fc9e3554460 401 SUPERFAMILY SSF51246 314 392 6.2E-17 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TL08_23525 19533178b5b1d9768ce15fc9e3554460 401 SUPERFAMILY SSF52440 3 95 2.16E-23 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_23525 19533178b5b1d9768ce15fc9e3554460 401 Pfam PF02222 ATP-grasp domain 109 288 3.6E-51 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TL08_23525 19533178b5b1d9768ce15fc9e3554460 401 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 3 370 39.543 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TL08_23525 19533178b5b1d9768ce15fc9e3554460 401 Gene3D G3DSA:3.30.1490.20 105 180 4.8E-16 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TL08_23525 19533178b5b1d9768ce15fc9e3554460 401 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 4 371 2.3E-118 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TL08_23525 19533178b5b1d9768ce15fc9e3554460 401 Gene3D G3DSA:3.40.50.20 1 104 1.5E-28 T 12-10-2018 TL08_23525 19533178b5b1d9768ce15fc9e3554460 401 Gene3D G3DSA:3.30.470.20 181 400 5.8E-68 T 12-10-2018 TL08_23525 19533178b5b1d9768ce15fc9e3554460 401 SUPERFAMILY SSF56059 100 308 2.47E-55 T 12-10-2018 TL08_23565 91e6b919385906859969b53932ae3d9d 261 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TL08_23565 91e6b919385906859969b53932ae3d9d 261 Pfam PF00459 Inositol monophosphatase family 9 241 5.8E-49 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_23565 91e6b919385906859969b53932ae3d9d 261 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 7 258 6.8E-86 T 12-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 TL08_23565 91e6b919385906859969b53932ae3d9d 261 Gene3D G3DSA:3.30.540.10 2 138 8.0E-44 T 12-10-2018 TL08_23565 91e6b919385906859969b53932ae3d9d 261 Gene3D G3DSA:3.40.190.80 146 259 4.0E-20 T 12-10-2018 TL08_23565 91e6b919385906859969b53932ae3d9d 261 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 TL08_23565 91e6b919385906859969b53932ae3d9d 261 SUPERFAMILY SSF56655 6 259 8.12E-73 T 12-10-2018 TL08_23565 91e6b919385906859969b53932ae3d9d 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 1.4E-21 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_23565 91e6b919385906859969b53932ae3d9d 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 1.4E-21 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_23565 91e6b919385906859969b53932ae3d9d 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 1.4E-21 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_23565 91e6b919385906859969b53932ae3d9d 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 1.4E-21 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_04820 2d4890442eed94353cde669cd94fab9f 1128 SUPERFAMILY SSF52540 3 787 1.42E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04820 2d4890442eed94353cde669cd94fab9f 1128 Gene3D G3DSA:3.40.50.300 2 287 3.5E-44 T 12-10-2018 TL08_04820 2d4890442eed94353cde669cd94fab9f 1128 Pfam PF13361 UvrD-like helicase C-terminal domain 681 769 2.9E-9 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TL08_04820 2d4890442eed94353cde669cd94fab9f 1128 Gene3D G3DSA:3.40.50.300 582 798 1.8E-20 T 12-10-2018 TL08_04820 2d4890442eed94353cde669cd94fab9f 1128 Gene3D G3DSA:1.10.10.160 102 208 3.5E-44 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily TL08_04820 2d4890442eed94353cde669cd94fab9f 1128 Gene3D G3DSA:3.40.50.300 435 531 1.5E-8 T 12-10-2018 TL08_04820 2d4890442eed94353cde669cd94fab9f 1128 Pfam PF12705 PD-(D/E)XK nuclease superfamily 870 1118 7.2E-34 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TL08_04820 2d4890442eed94353cde669cd94fab9f 1128 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 289 3.5E-33 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TL08_15610 011b659334045e55987e9545b00b50f0 805 SMART SM00958 255 363 2.9E-26 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TL08_15610 011b659334045e55987e9545b00b50f0 805 PRINTS PR00906 SecA protein signature 124 138 1.5E-36 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_15610 011b659334045e55987e9545b00b50f0 805 PRINTS PR00906 SecA protein signature 193 213 1.5E-36 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_15610 011b659334045e55987e9545b00b50f0 805 PRINTS PR00906 SecA protein signature 381 398 1.5E-36 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_15610 011b659334045e55987e9545b00b50f0 805 PRINTS PR00906 SecA protein signature 418 431 1.5E-36 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_15610 011b659334045e55987e9545b00b50f0 805 PRINTS PR00906 SecA protein signature 86 110 1.5E-36 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_15610 011b659334045e55987e9545b00b50f0 805 PRINTS PR00906 SecA protein signature 344 366 1.5E-36 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_15610 011b659334045e55987e9545b00b50f0 805 SMART SM00957 12 407 1.8E-129 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TL08_15610 011b659334045e55987e9545b00b50f0 805 SUPERFAMILY SSF52540 10 578 2.18E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_15610 011b659334045e55987e9545b00b50f0 805 Gene3D G3DSA:3.40.50.300 78 420 5.9E-114 T 12-10-2018 TL08_15610 011b659334045e55987e9545b00b50f0 805 Pfam PF01043 SecA preprotein cross-linking domain 260 363 5.4E-22 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TL08_15610 011b659334045e55987e9545b00b50f0 805 Pfam PF07517 SecA DEAD-like domain 14 406 6.7E-80 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TL08_15610 011b659334045e55987e9545b00b50f0 805 Gene3D G3DSA:3.90.1440.10 252 373 5.9E-114 T 12-10-2018 TL08_15610 011b659334045e55987e9545b00b50f0 805 Gene3D G3DSA:3.40.50.300 525 596 2.4E-18 T 12-10-2018 TL08_15610 011b659334045e55987e9545b00b50f0 805 Gene3D G3DSA:3.40.50.300 422 524 2.4E-36 T 12-10-2018 TL08_15610 011b659334045e55987e9545b00b50f0 805 Pfam PF07516 SecA Wing and Scaffold domain 657 736 4.8E-12 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TL08_15610 011b659334045e55987e9545b00b50f0 805 SUPERFAMILY SSF52540 422 584 2.56E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_15610 011b659334045e55987e9545b00b50f0 805 SUPERFAMILY SSF81767 261 371 7.32E-29 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 TL08_15610 011b659334045e55987e9545b00b50f0 805 SUPERFAMILY SSF81886 604 749 7.85E-26 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily TL08_15610 011b659334045e55987e9545b00b50f0 805 Gene3D G3DSA:1.10.3060.10 602 752 3.1E-22 T 12-10-2018 TL08_15610 011b659334045e55987e9545b00b50f0 805 Hamap MF_01382 Protein translocase subunit SecA [secA]. 11 748 14.904 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TL08_15610 011b659334045e55987e9545b00b50f0 805 ProSitePatterns PS01312 SecA family signature. 505 520 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 TL08_15610 011b659334045e55987e9545b00b50f0 805 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 9 787 0.0 T 12-10-2018 IPR026389 Protein translocase subunit SecA, Actinobacteria-type TL08_13800 37f9f8f3bcbd1148a54883bf41c57189 180 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 21 87 5.0E-5 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TL08_13800 37f9f8f3bcbd1148a54883bf41c57189 180 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 91 170 8.6E-36 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TL08_13800 37f9f8f3bcbd1148a54883bf41c57189 180 SUPERFAMILY SSF46767 90 171 7.85E-33 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TL08_13800 37f9f8f3bcbd1148a54883bf41c57189 180 Gene3D G3DSA:3.30.160.70 18 86 5.3E-21 T 12-10-2018 TL08_13800 37f9f8f3bcbd1148a54883bf41c57189 180 SUPERFAMILY SSF53155 19 95 1.31E-19 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TL08_13800 37f9f8f3bcbd1148a54883bf41c57189 180 Gene3D G3DSA:1.10.10.10 89 173 8.8E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_13800 37f9f8f3bcbd1148a54883bf41c57189 180 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 92 171 2.2E-34 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TL08_13800 37f9f8f3bcbd1148a54883bf41c57189 180 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 141 147 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TL08_13800 37f9f8f3bcbd1148a54883bf41c57189 180 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 22 171 43.11 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 TL08_24785 308a05ac2e1a53fd56f4c07712183091 190 SUPERFAMILY SSF88659 110 185 2.62E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_24785 308a05ac2e1a53fd56f4c07712183091 190 SUPERFAMILY SSF88946 12 112 2.51E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_24785 308a05ac2e1a53fd56f4c07712183091 190 Gene3D G3DSA:1.10.1740.10 6 96 5.8E-14 T 12-10-2018 TL08_24785 308a05ac2e1a53fd56f4c07712183091 190 Pfam PF04542 Sigma-70 region 2 26 98 3.8E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_24785 308a05ac2e1a53fd56f4c07712183091 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 184 6.0E-26 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_24785 308a05ac2e1a53fd56f4c07712183091 190 Gene3D G3DSA:1.10.10.10 110 188 7.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_24785 308a05ac2e1a53fd56f4c07712183091 190 Pfam PF08281 Sigma-70, region 4 130 180 5.4E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_26535 8e8d842a93f81c541e340e2a9e967afc 288 SUPERFAMILY SSF52540 18 248 5.85E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26535 8e8d842a93f81c541e340e2a9e967afc 288 SMART SM00382 50 235 1.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_26535 8e8d842a93f81c541e340e2a9e967afc 288 Pfam PF00005 ABC transporter 41 188 1.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_26535 8e8d842a93f81c541e340e2a9e967afc 288 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_26535 8e8d842a93f81c541e340e2a9e967afc 288 Gene3D G3DSA:3.40.50.300 18 276 2.5E-67 T 12-10-2018 TL08_25035 8f495e89ce4381eb6f38962fae80350d 215 SUPERFAMILY SSF53335 37 211 3.98E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_25035 8f495e89ce4381eb6f38962fae80350d 215 Pfam PF01596 O-methyltransferase 22 209 8.5E-37 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 TL08_25035 8f495e89ce4381eb6f38962fae80350d 215 Gene3D G3DSA:3.40.50.150 7 212 6.4E-65 T 12-10-2018 TL08_19510 449fe02c66aa65d79f58adf14b68d97a 197 SUPERFAMILY SSF48498 99 192 5.09E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_19510 449fe02c66aa65d79f58adf14b68d97a 197 Gene3D G3DSA:1.10.357.10 66 195 6.0E-16 T 12-10-2018 TL08_19510 449fe02c66aa65d79f58adf14b68d97a 197 Gene3D G3DSA:1.10.10.60 1 65 9.5E-26 T 12-10-2018 TL08_19510 449fe02c66aa65d79f58adf14b68d97a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.9E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19510 449fe02c66aa65d79f58adf14b68d97a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.9E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19510 449fe02c66aa65d79f58adf14b68d97a 197 SUPERFAMILY SSF46689 3 82 3.18E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_19510 449fe02c66aa65d79f58adf14b68d97a 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 4.6E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_04270 e9242d74c24f866b384184d21a80ace2 293 Gene3D G3DSA:1.10.10.10 93 165 2.1E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04270 e9242d74c24f866b384184d21a80ace2 293 Pfam PF04542 Sigma-70 region 2 13 77 2.8E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_04270 e9242d74c24f866b384184d21a80ace2 293 Pfam PF04545 Sigma-70, region 4 114 160 1.0E-7 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TL08_04270 e9242d74c24f866b384184d21a80ace2 293 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 161 9.7E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_04270 e9242d74c24f866b384184d21a80ace2 293 SUPERFAMILY SSF88946 10 91 7.46E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_04270 e9242d74c24f866b384184d21a80ace2 293 Gene3D G3DSA:1.10.1740.10 2 80 8.3E-7 T 12-10-2018 TL08_04270 e9242d74c24f866b384184d21a80ace2 293 SUPERFAMILY SSF54427 175 285 1.21E-13 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_04270 e9242d74c24f866b384184d21a80ace2 293 Gene3D G3DSA:3.10.450.50 168 287 4.6E-5 T 12-10-2018 TL08_04270 e9242d74c24f866b384184d21a80ace2 293 SUPERFAMILY SSF88659 79 163 3.18E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_04270 e9242d74c24f866b384184d21a80ace2 293 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 12 285 3.8E-103 T 12-10-2018 IPR014303 RNA polymerase sigma-70, ECF type TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 50 279 3.3E-77 T 12-10-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 Pfam PF00881 Nitroreductase family 297 465 4.3E-25 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 SUPERFAMILY SSF144010 51 283 4.97E-65 T 12-10-2018 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 Gene3D G3DSA:3.40.109.10 281 484 1.3E-50 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 SUPERFAMILY SSF55469 291 484 3.14E-36 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 54 486 49.285 T 12-10-2018 IPR023661 Coenzyme F420:L-glutamate ligase, Actinobacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 Gene3D G3DSA:3.90.1660.10 97 279 4.9E-67 T 12-10-2018 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 Pfam PF01996 F420-0:Gamma-glutamyl ligase 113 256 1.3E-32 T 12-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 Pfam PF01996 F420-0:Gamma-glutamyl ligase 57 100 6.4E-7 T 12-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 292 484 3.1E-92 T 12-10-2018 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 TL08_23385 d543aa0c70eb10d9483d56e92daebc7f 486 Gene3D G3DSA:3.30.1330.100 52 265 4.9E-67 T 12-10-2018 TL08_11955 08bfd16d1a94d50ee711b917a13fabee 340 SUPERFAMILY SSF48576 8 310 5.12E-70 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_11955 08bfd16d1a94d50ee711b917a13fabee 340 Gene3D G3DSA:1.10.600.10 2 327 1.3E-80 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_11955 08bfd16d1a94d50ee711b917a13fabee 340 Pfam PF00348 Polyprenyl synthetase 38 268 1.4E-56 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TL08_11955 08bfd16d1a94d50ee711b917a13fabee 340 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 209 221 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TL08_04735 a451d8e47c0893057a1cbc418cb72dbc 310 Gene3D G3DSA:1.10.150.650 121 193 8.6E-73 T 12-10-2018 TL08_04735 a451d8e47c0893057a1cbc418cb72dbc 310 Pfam PF02811 PHP domain 25 102 4.1E-7 T 12-10-2018 IPR004013 PHP domain GO:0003824 TL08_04735 a451d8e47c0893057a1cbc418cb72dbc 310 SUPERFAMILY SSF89550 22 281 4.45E-41 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TL08_04735 a451d8e47c0893057a1cbc418cb72dbc 310 Gene3D G3DSA:3.20.20.140 24 274 8.6E-73 T 12-10-2018 TL08_04735 a451d8e47c0893057a1cbc418cb72dbc 310 SMART SM00481 24 88 5.7E-15 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TL08_11650 afe7b059f2f7ae5f2050e89e7fed1ee2 310 Pfam PF04542 Sigma-70 region 2 11 74 5.4E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_11650 afe7b059f2f7ae5f2050e89e7fed1ee2 310 Pfam PF08281 Sigma-70, region 4 116 168 2.5E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_11650 afe7b059f2f7ae5f2050e89e7fed1ee2 310 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 170 3.0E-16 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_11650 afe7b059f2f7ae5f2050e89e7fed1ee2 310 SUPERFAMILY SSF54427 181 290 9.87E-8 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_11650 afe7b059f2f7ae5f2050e89e7fed1ee2 310 Gene3D G3DSA:1.10.1740.10 1 78 3.7E-11 T 12-10-2018 TL08_11650 afe7b059f2f7ae5f2050e89e7fed1ee2 310 SUPERFAMILY SSF88659 109 170 1.08E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_11650 afe7b059f2f7ae5f2050e89e7fed1ee2 310 SUPERFAMILY SSF88946 7 89 1.53E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_11650 afe7b059f2f7ae5f2050e89e7fed1ee2 310 Gene3D G3DSA:1.10.10.10 89 174 1.3E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11435 78c5948c0c6680c308e49686d45fae6e 144 Gene3D G3DSA:3.40.50.9100 1 143 1.7E-57 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TL08_11435 78c5948c0c6680c308e49686d45fae6e 144 Pfam PF01220 Dehydroquinase class II 4 138 8.1E-53 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TL08_11435 78c5948c0c6680c308e49686d45fae6e 144 SUPERFAMILY SSF52304 2 141 2.22E-54 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TL08_11435 78c5948c0c6680c308e49686d45fae6e 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 140 2.4E-56 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TL08_11435 78c5948c0c6680c308e49686d45fae6e 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 6 23 - T 12-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TL08_11435 78c5948c0c6680c308e49686d45fae6e 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 140 1.0E-40 T 12-10-2018 TL08_11435 78c5948c0c6680c308e49686d45fae6e 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 59.884 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TL08_11435 78c5948c0c6680c308e49686d45fae6e 144 PIRSF PIRSF001399 1 143 5.7E-56 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TL08_06055 517c4d71a6e0bf706eb704e8485cae0d 280 SUPERFAMILY SSF51215 27 143 1.2E-22 T 12-10-2018 IPR037923 Transcription regulator HTH-like TL08_06055 517c4d71a6e0bf706eb704e8485cae0d 280 Gene3D G3DSA:1.10.10.60 177 279 1.9E-26 T 12-10-2018 TL08_06055 517c4d71a6e0bf706eb704e8485cae0d 280 SUPERFAMILY SSF46689 228 275 1.65E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06055 517c4d71a6e0bf706eb704e8485cae0d 280 Pfam PF12833 Helix-turn-helix domain 198 275 6.1E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_06055 517c4d71a6e0bf706eb704e8485cae0d 280 Pfam PF02311 AraC-like ligand binding domain 21 144 2.7E-24 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TL08_06055 517c4d71a6e0bf706eb704e8485cae0d 280 SUPERFAMILY SSF46689 178 227 3.94E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06055 517c4d71a6e0bf706eb704e8485cae0d 280 SMART SM00342 192 274 1.5E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_07750 383f61f9b5bd416bdd7f6a41808bdf2e 224 SMART SM00448 3 114 9.1E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_07750 383f61f9b5bd416bdd7f6a41808bdf2e 224 Gene3D G3DSA:1.10.10.10 125 222 1.5E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07750 383f61f9b5bd416bdd7f6a41808bdf2e 224 Pfam PF00072 Response regulator receiver domain 5 114 1.5E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_07750 383f61f9b5bd416bdd7f6a41808bdf2e 224 Gene3D G3DSA:3.40.50.2300 1 124 2.5E-29 T 12-10-2018 TL08_07750 383f61f9b5bd416bdd7f6a41808bdf2e 224 SUPERFAMILY SSF52172 3 180 1.27E-34 T 12-10-2018 IPR011006 CheY-like superfamily TL08_07750 383f61f9b5bd416bdd7f6a41808bdf2e 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 219 3.9E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_07750 383f61f9b5bd416bdd7f6a41808bdf2e 224 SMART SM00862 147 219 1.6E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_13705 81af578dddda0615023b34251cf3e305 353 Gene3D G3DSA:1.10.3470.10 27 351 2.1E-70 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_13705 81af578dddda0615023b34251cf3e305 353 Pfam PF01032 FecCD transport family 42 346 6.5E-66 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_13705 81af578dddda0615023b34251cf3e305 353 SUPERFAMILY SSF81345 23 346 1.83E-57 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_08120 526cbd55ced571dc8d45a346c134a00e 310 Pfam PF00005 ABC transporter 25 166 2.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_08120 526cbd55ced571dc8d45a346c134a00e 310 Gene3D G3DSA:3.40.50.300 4 239 1.9E-68 T 12-10-2018 TL08_08120 526cbd55ced571dc8d45a346c134a00e 310 SMART SM00382 32 215 1.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08120 526cbd55ced571dc8d45a346c134a00e 310 SUPERFAMILY SSF52540 7 230 3.45E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08120 526cbd55ced571dc8d45a346c134a00e 310 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_18455 eb7edccde35844c93a692af199272b07 433 Pfam PF00144 Beta-lactamase 74 414 6.1E-53 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_18455 eb7edccde35844c93a692af199272b07 433 SUPERFAMILY SSF56601 67 410 2.51E-66 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_18455 eb7edccde35844c93a692af199272b07 433 Gene3D G3DSA:3.40.710.10 62 410 1.1E-82 T 12-10-2018 TL08_04175 d77319fe8b07add34b6daf49cea70aef 201 Pfam PF14030 Protein of unknown function (DUF4245) 17 192 2.7E-37 T 12-10-2018 IPR025339 Protein of unknown function DUF4245 TL08_16390 c852cba65c42488775acb007f0d7bfa0 171 SUPERFAMILY SSF81296 31 171 1.68E-30 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_16390 c852cba65c42488775acb007f0d7bfa0 171 Gene3D G3DSA:2.70.50.50 31 171 1.7E-46 T 12-10-2018 TL08_16390 c852cba65c42488775acb007f0d7bfa0 171 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 168 2.3E-11 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal TL08_01760 d3276264dabd62af5e93d5842ce552cc 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 74 1.4E-18 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TL08_01760 d3276264dabd62af5e93d5842ce552cc 103 SUPERFAMILY SSF54909 1 97 1.36E-24 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_01760 d3276264dabd62af5e93d5842ce552cc 103 Gene3D G3DSA:3.30.70.100 1 99 4.8E-38 T 12-10-2018 TL08_00670 1ba28a823b1ea6815ebb24826d461d47 138 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 3 106 3.8E-22 T 12-10-2018 IPR019277 Protein of unknown function DUF2304 TL08_14900 7eac3b3bf0ede0c0723f6bd3191c9e91 339 PIRSF PIRSF000446 12 321 4.2E-84 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TL08_14900 7eac3b3bf0ede0c0723f6bd3191c9e91 339 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 18 331 5.7E-37 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14900 7eac3b3bf0ede0c0723f6bd3191c9e91 339 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 14 294 1.8E-84 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TL08_14900 7eac3b3bf0ede0c0723f6bd3191c9e91 339 SUPERFAMILY SSF55048 137 207 2.75E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14900 7eac3b3bf0ede0c0723f6bd3191c9e91 339 SUPERFAMILY SSF52151 15 319 1.05E-69 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14900 7eac3b3bf0ede0c0723f6bd3191c9e91 339 Gene3D G3DSA:3.40.366.10 16 295 5.5E-91 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14900 7eac3b3bf0ede0c0723f6bd3191c9e91 339 Pfam PF00698 Acyl transferase domain 18 292 1.2E-35 T 12-10-2018 IPR014043 Acyl transferase TL08_14900 7eac3b3bf0ede0c0723f6bd3191c9e91 339 Gene3D G3DSA:3.30.70.250 137 207 5.5E-91 T 12-10-2018 TL08_23205 95c8a168c400bbf7472d0d8a398f58db 261 Gene3D G3DSA:3.90.1680.10 1 243 1.7E-63 T 12-10-2018 IPR036590 SOS response associated peptidase-like TL08_23205 95c8a168c400bbf7472d0d8a398f58db 261 SUPERFAMILY SSF143081 2 241 1.57E-63 T 12-10-2018 IPR036590 SOS response associated peptidase-like TL08_23205 95c8a168c400bbf7472d0d8a398f58db 261 Pfam PF02586 SOS response associated peptidase (SRAP) 1 232 5.8E-63 T 12-10-2018 IPR003738 SOS response associated peptidase (SRAP) TL08_19305 6a255be81969e544204d9b85a51fe8da 314 Gene3D G3DSA:3.40.1190.20 1 307 1.1E-94 T 12-10-2018 IPR029056 Ribokinase-like TL08_19305 6a255be81969e544204d9b85a51fe8da 314 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 2.9E-92 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TL08_19305 6a255be81969e544204d9b85a51fe8da 314 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 299 6.2E-90 T 12-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 TL08_19305 6a255be81969e544204d9b85a51fe8da 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TL08_19305 6a255be81969e544204d9b85a51fe8da 314 PIRSF PIRSF000535 1 304 4.8E-69 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TL08_19305 6a255be81969e544204d9b85a51fe8da 314 SUPERFAMILY SSF53613 2 291 3.59E-59 T 12-10-2018 IPR029056 Ribokinase-like TL08_19305 6a255be81969e544204d9b85a51fe8da 314 Pfam PF00294 pfkB family carbohydrate kinase 23 291 2.7E-42 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_20635 5711b8f79df1313b83a005d8c8e447f1 142 Gene3D G3DSA:3.30.70.2010 17 136 4.2E-6 T 12-10-2018 TL08_02375 dce282ae5e942cf5f02cecded050d833 275 Gene3D G3DSA:3.40.50.720 106 237 9.8E-43 T 12-10-2018 TL08_02375 dce282ae5e942cf5f02cecded050d833 275 Pfam PF06971 Putative DNA-binding protein N-terminus 35 82 5.8E-18 T 12-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 TL08_02375 dce282ae5e942cf5f02cecded050d833 275 Gene3D G3DSA:1.10.10.10 34 105 2.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_02375 dce282ae5e942cf5f02cecded050d833 275 SMART SM00881 108 209 8.0E-17 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TL08_02375 dce282ae5e942cf5f02cecded050d833 275 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 30 238 34.637 T 12-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 TL08_02375 dce282ae5e942cf5f02cecded050d833 275 Pfam PF02629 CoA binding domain 111 208 9.7E-19 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TL08_02375 dce282ae5e942cf5f02cecded050d833 275 SUPERFAMILY SSF51735 113 233 5.06E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_02375 dce282ae5e942cf5f02cecded050d833 275 SUPERFAMILY SSF46785 36 108 2.58E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_20095 2cc8bbe144d50e725cb15404650b31f5 202 SUPERFAMILY SSF46689 11 75 5.49E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_20095 2cc8bbe144d50e725cb15404650b31f5 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 1.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_20095 2cc8bbe144d50e725cb15404650b31f5 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_20095 2cc8bbe144d50e725cb15404650b31f5 202 Gene3D G3DSA:1.10.357.10 15 192 2.3E-31 T 12-10-2018 TL08_20095 2cc8bbe144d50e725cb15404650b31f5 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 62 9.2E-19 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_20095 2cc8bbe144d50e725cb15404650b31f5 202 SUPERFAMILY SSF48498 105 182 4.45E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_16035 6fd942d19f02e405c337471366f2dd12 143 SUPERFAMILY SSF103473 1 140 6.28E-12 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_16035 6fd942d19f02e405c337471366f2dd12 143 Gene3D G3DSA:1.20.1250.20 1 136 3.9E-9 T 12-10-2018 TL08_19995 704cb16c0e71a26bc5f23a7e771fb496 200 Gene3D G3DSA:3.40.50.300 15 196 3.0E-15 T 12-10-2018 TL08_19995 704cb16c0e71a26bc5f23a7e771fb496 200 Pfam PF03029 Conserved hypothetical ATP binding protein 23 188 2.7E-24 T 12-10-2018 IPR004130 GPN-loop GTPase TL08_19995 704cb16c0e71a26bc5f23a7e771fb496 200 SUPERFAMILY SSF52540 19 192 5.02E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06605 6a95f0063697c90fb12d5910ca744554 267 SUPERFAMILY SSF52540 5 242 1.46E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06605 6a95f0063697c90fb12d5910ca744554 267 Pfam PF00005 ABC transporter 25 175 3.4E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_06605 6a95f0063697c90fb12d5910ca744554 267 SMART SM00382 33 256 3.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_06605 6a95f0063697c90fb12d5910ca744554 267 Gene3D G3DSA:3.40.50.300 1 263 4.2E-54 T 12-10-2018 TL08_18445 60ecbcd54e31ec01e47ccf8b3c2c660c 527 SUPERFAMILY SSF63829 307 517 1.28E-28 T 12-10-2018 TL08_18445 60ecbcd54e31ec01e47ccf8b3c2c660c 527 SUPERFAMILY SSF63825 8 203 4.58E-28 T 12-10-2018 TL08_18445 60ecbcd54e31ec01e47ccf8b3c2c660c 527 Gene3D G3DSA:2.120.10.30 309 527 2.5E-24 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_18445 60ecbcd54e31ec01e47ccf8b3c2c660c 527 Gene3D G3DSA:2.120.10.30 168 288 7.6E-11 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_18445 60ecbcd54e31ec01e47ccf8b3c2c660c 527 SUPERFAMILY SSF63829 205 277 1.44E-7 T 12-10-2018 TL08_18445 60ecbcd54e31ec01e47ccf8b3c2c660c 527 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 313 523 1.0E-8 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region TL08_18445 60ecbcd54e31ec01e47ccf8b3c2c660c 527 Gene3D G3DSA:2.120.10.30 4 144 1.5E-16 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 PRINTS PR00364 Disease resistance protein signature 239 253 2.2E-5 T 12-10-2018 TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 PRINTS PR00364 Disease resistance protein signature 78 93 2.2E-5 T 12-10-2018 TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 PRINTS PR00364 Disease resistance protein signature 154 168 2.2E-5 T 12-10-2018 TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 Gene3D G3DSA:1.25.40.10 558 731 4.5E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 Gene3D G3DSA:3.40.50.300 40 203 1.5E-25 T 12-10-2018 TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 SUPERFAMILY SSF48452 569 687 1.9E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 Pfam PF13374 Tetratricopeptide repeat 615 656 3.3E-4 T 12-10-2018 TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 SUPERFAMILY SSF52540 75 263 1.44E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 Gene3D G3DSA:1.25.40.10 416 557 5.5E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 SUPERFAMILY SSF48452 444 559 2.14E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05760 d8be397a4788f0e10f9b2d721d64d008 752 Pfam PF00931 NB-ARC domain 81 256 1.4E-13 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_13345 da57e31f27361fcb37b964d25efcab17 222 SUPERFAMILY SSF81296 25 221 3.64E-31 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_13345 da57e31f27361fcb37b964d25efcab17 222 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 25 219 3.1E-32 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal TL08_13345 da57e31f27361fcb37b964d25efcab17 222 Gene3D G3DSA:2.70.50.50 25 222 2.8E-62 T 12-10-2018 TL08_17620 55474dc7869b994127038c681aa48a99 272 SUPERFAMILY SSF53335 33 256 5.84E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_17620 55474dc7869b994127038c681aa48a99 272 Pfam PF13847 Methyltransferase domain 62 183 1.0E-13 T 12-10-2018 IPR025714 Methyltransferase domain TL08_17620 55474dc7869b994127038c681aa48a99 272 Gene3D G3DSA:3.40.50.150 30 272 2.3E-76 T 12-10-2018 TL08_03715 96b4572a811f82f4b172296ef11b32c8 318 PRINTS PR00075 Fatty acid desaturase family 1 signature 217 238 3.4E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 TL08_03715 96b4572a811f82f4b172296ef11b32c8 318 PRINTS PR00075 Fatty acid desaturase family 1 signature 57 79 3.4E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 TL08_03715 96b4572a811f82f4b172296ef11b32c8 318 PRINTS PR00075 Fatty acid desaturase family 1 signature 80 100 3.4E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 TL08_03715 96b4572a811f82f4b172296ef11b32c8 318 PRINTS PR00075 Fatty acid desaturase family 1 signature 260 274 3.4E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 TL08_03715 96b4572a811f82f4b172296ef11b32c8 318 Pfam PF00487 Fatty acid desaturase 57 276 7.5E-21 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 TL08_25090 d59dbb34b83fe4434144ba87425a8bea 306 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_25090 d59dbb34b83fe4434144ba87425a8bea 306 Pfam PF13732 Domain of unknown function (DUF4162) 218 300 5.0E-9 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 TL08_25090 d59dbb34b83fe4434144ba87425a8bea 306 Gene3D G3DSA:3.40.50.300 2 234 2.6E-63 T 12-10-2018 TL08_25090 d59dbb34b83fe4434144ba87425a8bea 306 Pfam PF00005 ABC transporter 24 164 6.9E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_25090 d59dbb34b83fe4434144ba87425a8bea 306 SMART SM00382 33 212 7.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_25090 d59dbb34b83fe4434144ba87425a8bea 306 SUPERFAMILY SSF52540 8 226 3.11E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24600 2f2c4d93b2e70f302e6b619b7b115346 135 Gene3D G3DSA:3.40.50.280 2 134 9.9E-58 T 12-10-2018 TL08_24600 2f2c4d93b2e70f302e6b619b7b115346 135 SUPERFAMILY SSF52242 3 130 4.32E-49 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TL08_24600 2f2c4d93b2e70f302e6b619b7b115346 135 Pfam PF02310 B12 binding domain 5 115 1.4E-22 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TL08_24600 2f2c4d93b2e70f302e6b619b7b115346 135 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 4 131 3.4E-50 T 12-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TL08_23135 66c55ff7c0cf1964a1391b9823a8f7de 394 Pfam PF03949 Malic enzyme, NAD binding domain 170 387 8.9E-19 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TL08_23135 66c55ff7c0cf1964a1391b9823a8f7de 394 SUPERFAMILY SSF53223 17 166 1.15E-48 T 12-10-2018 TL08_23135 66c55ff7c0cf1964a1391b9823a8f7de 394 Gene3D G3DSA:3.40.50.10380 9 165 1.4E-61 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 TL08_23135 66c55ff7c0cf1964a1391b9823a8f7de 394 SUPERFAMILY SSF51735 168 392 2.06E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_23135 66c55ff7c0cf1964a1391b9823a8f7de 394 Pfam PF00390 Malic enzyme, N-terminal domain 33 119 1.0E-18 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TL08_23135 66c55ff7c0cf1964a1391b9823a8f7de 394 SMART SM00919 168 388 6.0E-98 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TL08_23135 66c55ff7c0cf1964a1391b9823a8f7de 394 SMART SM01274 23 156 1.5E-67 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TL08_23135 66c55ff7c0cf1964a1391b9823a8f7de 394 PIRSF PIRSF000106 38 394 5.3E-64 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TL08_23135 66c55ff7c0cf1964a1391b9823a8f7de 394 Gene3D G3DSA:3.40.50.720 166 393 7.0E-66 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1446 1457 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 176 192 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SUPERFAMILY SSF53901 14 432 4.05E-71 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:1.10.1200.10 1803 1885 2.6E-19 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SUPERFAMILY SSF56801 1300 1825 2.88E-116 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:3.30.70.3050 483 536 1.3E-162 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:3.40.47.10 16 482 1.3E-162 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:3.30.559.10 849 1216 2.2E-109 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:3.30.559.30 2058 2298 2.4E-11 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SMART SM00823 Phosphopantetheine attachment site 758 827 0.019 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SMART SM00823 Phosphopantetheine attachment site 1814 1883 1.8E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:3.30.300.30 1698 1802 2.4E-30 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SUPERFAMILY SSF47336 753 860 2.36E-12 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1838 1853 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Pfam PF00550 Phosphopantetheine attachment site 764 823 3.1E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Pfam PF00550 Phosphopantetheine attachment site 1816 1878 7.1E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:3.30.559.30 1025 1272 2.2E-109 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SUPERFAMILY SSF52777 850 1021 8.67E-35 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 270 388 1.4E-37 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1329 1726 5.2E-101 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Pfam PF00668 Condensation domain 1919 2222 3.5E-18 T 12-10-2018 IPR001242 Condensation domain TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Pfam PF00668 Condensation domain 848 1276 7.7E-74 T 12-10-2018 IPR001242 Condensation domain TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SMART SM00825 Beta-ketoacyl synthase 16 438 2.6E-146 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Pfam PF13193 AMP-binding enzyme C-terminal domain 1711 1788 4.3E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:3.30.559.10 1886 2043 5.9E-19 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SUPERFAMILY SSF52777 1027 1272 4.89E-54 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:3.40.50.12780 1294 1697 8.4E-104 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SUPERFAMILY SSF47336 1810 1879 4.32E-15 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SUPERFAMILY SSF52777 1916 2060 5.45E-20 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 15 262 8.5E-58 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Pfam PF00501 AMP-binding enzyme 1310 1703 5.8E-71 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 391 493 1.3E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 SUPERFAMILY SSF52777 2082 2290 1.56E-13 T 12-10-2018 TL08_14890 a38469ce414ba56899d20e0babaf8171 2299 Gene3D G3DSA:1.10.1200.10 747 829 1.7E-11 T 12-10-2018 IPR036736 ACP-like superfamily TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 SUPERFAMILY SSF143548 325 453 1.31E-31 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 Gene3D G3DSA:3.40.50.720 101 282 3.1E-120 T 12-10-2018 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 Pfam PF01842 ACT domain 459 517 2.6E-9 T 12-10-2018 IPR002912 ACT domain TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 Gene3D G3DSA:3.30.1330.90 319 457 1.1E-42 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 Gene3D G3DSA:3.30.70.260 458 531 3.3E-19 T 12-10-2018 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 SUPERFAMILY SSF52283 6 137 8.32E-37 T 12-10-2018 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 SUPERFAMILY SSF51735 103 285 7.53E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 10 316 3.8E-34 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 Gene3D G3DSA:3.40.50.720 10 308 3.1E-120 T 12-10-2018 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 10 529 6.6E-187 T 12-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 SUPERFAMILY SSF55021 456 526 1.93E-13 T 12-10-2018 TL08_22715 6fe610d842baa89e01272e34bb6d1707 532 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 284 5.4E-60 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TL08_09480 2ffa7821761cb2e109aa3a3d6f90ed6c 449 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 15 366 1.3E-114 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_09480 2ffa7821761cb2e109aa3a3d6f90ed6c 449 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 325 349 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_09480 2ffa7821761cb2e109aa3a3d6f90ed6c 449 Pfam PF01098 Cell cycle protein 14 367 2.5E-113 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 Gene3D G3DSA:3.30.420.10 33 203 1.5E-48 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 SUPERFAMILY SSF82771 238 316 1.07E-14 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 SMART SM00479 37 205 5.9E-46 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 SMART SM00465 238 319 8.8E-11 T 12-10-2018 IPR000305 GIY-YIG endonuclease TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 SUPERFAMILY SSF46600 413 456 8.89E-6 T 12-10-2018 IPR036876 UVR domain superfamily TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 Pfam PF01541 GIY-YIG catalytic domain 240 314 2.4E-5 T 12-10-2018 IPR000305 GIY-YIG endonuclease TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 33 200 1.7E-31 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 Pfam PF00929 Exonuclease 39 196 9.0E-34 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 SUPERFAMILY SSF53098 32 217 3.35E-54 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_21735 aeb25c89f331e83be29b6524e1616dc2 585 Gene3D G3DSA:3.40.1440.10 224 321 3.9E-23 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TL08_07645 ec10bb4dc677c647691193b88a8bef03 474 Gene3D G3DSA:3.60.40.10 2 237 6.4E-62 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_07645 ec10bb4dc677c647691193b88a8bef03 474 SUPERFAMILY SSF81606 5 235 4.45E-59 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_07645 ec10bb4dc677c647691193b88a8bef03 474 Pfam PF13672 Protein phosphatase 2C 19 197 3.6E-11 T 12-10-2018 TL08_07645 ec10bb4dc677c647691193b88a8bef03 474 SMART SM00331 11 236 4.1E-37 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_07645 ec10bb4dc677c647691193b88a8bef03 474 SMART SM00332 2 234 3.1E-21 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_20140 af6fc1f25ade7ef85458704d37a3bcd7 255 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 225 2.3E-56 T 12-10-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 TL08_20140 af6fc1f25ade7ef85458704d37a3bcd7 255 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 223 2.8E-43 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 TL08_20140 af6fc1f25ade7ef85458704d37a3bcd7 255 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 42 8.9E-10 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 1.9E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 1.9E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 1.9E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 1.9E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 1.9E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 1.9E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 Gene3D G3DSA:3.20.20.70 1 325 5.9E-133 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 SMART SM01004 2 322 3.5E-203 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 PIRSF PIRSF001415 1 325 3.2E-141 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 Pfam PF00490 Delta-aminolevulinic acid dehydratase 5 321 4.3E-134 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TL08_02395 ebd7e99b5630be3b0bf6ede11354ffd7 325 SUPERFAMILY SSF51569 1 324 2.34E-127 T 12-10-2018 TL08_14085 4011d27672f653f06ead0ba01464833e 142 Gene3D G3DSA:1.10.10.10 21 141 7.5E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_14085 4011d27672f653f06ead0ba01464833e 142 SUPERFAMILY SSF46785 28 138 1.54E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_14085 4011d27672f653f06ead0ba01464833e 142 Pfam PF01638 HxlR-like helix-turn-helix 42 128 6.4E-23 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_04100 d7bb632907a86af5f6d965792b252dd9 702 SUPERFAMILY SSF48208 187 559 6.8E-69 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_04100 d7bb632907a86af5f6d965792b252dd9 702 SUPERFAMILY SSF52833 2 127 2.16E-29 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_04100 d7bb632907a86af5f6d965792b252dd9 702 PIRSF PIRSF006402 1 702 1.8E-204 T 12-10-2018 IPR024705 Spermatogenesis-associated protein 20 TL08_04100 d7bb632907a86af5f6d965792b252dd9 702 Gene3D G3DSA:3.40.30.10 1 169 1.9E-67 T 12-10-2018 TL08_04100 d7bb632907a86af5f6d965792b252dd9 702 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 225 313 0.6 T 12-10-2018 TL08_04100 d7bb632907a86af5f6d965792b252dd9 702 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 502 552 0.24 T 12-10-2018 TL08_04100 d7bb632907a86af5f6d965792b252dd9 702 Pfam PF03190 Protein of unknown function, DUF255 3 162 2.0E-73 T 12-10-2018 IPR004879 Domain of unknown function DUF255 TL08_06510 a0ab10895fc8f9d98df4e7c4f0f82736 192 SUPERFAMILY SSF144091 4 177 1.57E-23 T 12-10-2018 TL08_06510 a0ab10895fc8f9d98df4e7c4f0f82736 192 Gene3D G3DSA:1.20.1540.10 4 180 1.4E-12 T 12-10-2018 IPR035952 Rhomboid-like superfamily TL08_06510 a0ab10895fc8f9d98df4e7c4f0f82736 192 Pfam PF01694 Rhomboid family 42 176 6.9E-21 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TL08_04290 4412a7ccc16d5db18a22418853b85898 282 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 40 67 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TL08_04290 4412a7ccc16d5db18a22418853b85898 282 SMART SM00650 24 185 3.3E-55 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TL08_04290 4412a7ccc16d5db18a22418853b85898 282 Pfam PF00398 Ribosomal RNA adenine dimethylase 10 255 8.3E-29 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TL08_04290 4412a7ccc16d5db18a22418853b85898 282 Gene3D G3DSA:3.40.50.150 4 186 6.2E-38 T 12-10-2018 TL08_04290 4412a7ccc16d5db18a22418853b85898 282 SUPERFAMILY SSF53335 11 258 5.68E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_05475 485ecd72d4b85fbf63f2a3532df21081 253 Pfam PF13411 MerR HTH family regulatory protein 5 68 3.6E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_05475 485ecd72d4b85fbf63f2a3532df21081 253 SMART SM00422 3 72 1.8E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_05475 485ecd72d4b85fbf63f2a3532df21081 253 SUPERFAMILY SSF46955 4 106 2.12E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_05475 485ecd72d4b85fbf63f2a3532df21081 253 Gene3D G3DSA:1.10.1660.10 6 249 1.2E-23 T 12-10-2018 TL08_03935 bd5e4ef1306db3c9095d0fde655a032b 249 SMART SM00530 7 67 2.1E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_03935 bd5e4ef1306db3c9095d0fde655a032b 249 SUPERFAMILY SSF47413 15 66 1.09E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_03935 bd5e4ef1306db3c9095d0fde655a032b 249 Pfam PF13560 Helix-turn-helix domain 15 70 9.4E-15 T 12-10-2018 TL08_03935 bd5e4ef1306db3c9095d0fde655a032b 249 Gene3D G3DSA:3.30.450.180 91 247 3.2E-7 T 12-10-2018 TL08_03935 bd5e4ef1306db3c9095d0fde655a032b 249 Gene3D G3DSA:1.10.260.40 6 78 3.2E-9 T 12-10-2018 TL08_17795 43dbe26ce961397ea86c2e03e856a879 792 SUPERFAMILY SSF51445 3 704 4.88E-118 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_17795 43dbe26ce961397ea86c2e03e856a879 792 Gene3D G3DSA:1.10.10.470 521 611 8.8E-173 T 12-10-2018 TL08_17795 43dbe26ce961397ea86c2e03e856a879 792 Pfam PF00128 Alpha amylase, catalytic domain 25 99 4.6E-13 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_17795 43dbe26ce961397ea86c2e03e856a879 792 Gene3D G3DSA:1.10.150.200 338 477 8.8E-173 T 12-10-2018 TL08_17795 43dbe26ce961397ea86c2e03e856a879 792 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 4 790 9.5E-249 T 12-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 TL08_17795 43dbe26ce961397ea86c2e03e856a879 792 SMART SM00642 4 690 3.7E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_17795 43dbe26ce961397ea86c2e03e856a879 792 Gene3D G3DSA:3.30.1590.10 90 226 8.8E-173 T 12-10-2018 TL08_17795 43dbe26ce961397ea86c2e03e856a879 792 Gene3D G3DSA:3.20.20.80 6 698 8.8E-173 T 12-10-2018 TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 Gene3D G3DSA:3.40.50.200 160 464 8.9E-39 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 Gene3D G3DSA:3.40.50.200 485 676 4.6E-30 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 Pfam PF02225 PA domain 443 532 1.6E-5 T 12-10-2018 IPR003137 PA domain TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 Pfam PF00082 Subtilase family 180 644 4.4E-42 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 PRINTS PR00723 Subtilisin serine protease family (S8) signature 257 270 1.1E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 PRINTS PR00723 Subtilisin serine protease family (S8) signature 607 623 1.1E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 PRINTS PR00723 Subtilisin serine protease family (S8) signature 180 199 1.1E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 SUPERFAMILY SSF52743 164 673 4.71E-66 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 608 618 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 261 271 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_22705 514ee7dfa9bfcc96fb1edcf62b0ed1b5 1110 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 185 196 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 Gene3D G3DSA:3.30.360.10 151 319 3.0E-146 T 12-10-2018 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 3.9E-35 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 317 1.8E-65 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 329 1.4E-131 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 SMART SM00846 3 152 4.0E-87 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 1.4E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 1.4E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 1.4E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 1.4E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 1.4E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 SUPERFAMILY SSF51735 3 168 2.01E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 Gene3D G3DSA:3.40.50.720 4 330 3.0E-146 T 12-10-2018 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 PIRSF PIRSF000149 1 338 3.3E-129 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11625 1798cddb7dd1b06f32799f29e8631153 339 SUPERFAMILY SSF55347 151 317 3.87E-70 T 12-10-2018 TL08_16015 60c683b06a044f200bafe18cf7d15093 406 Gene3D G3DSA:3.50.50.60 13 349 1.2E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_16015 60c683b06a044f200bafe18cf7d15093 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 1.4E-10 T 12-10-2018 TL08_16015 60c683b06a044f200bafe18cf7d15093 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 1.4E-10 T 12-10-2018 TL08_16015 60c683b06a044f200bafe18cf7d15093 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 1.4E-10 T 12-10-2018 TL08_16015 60c683b06a044f200bafe18cf7d15093 406 SUPERFAMILY SSF51905 10 379 5.46E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_16015 60c683b06a044f200bafe18cf7d15093 406 Pfam PF01494 FAD binding domain 120 324 1.8E-11 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_16015 60c683b06a044f200bafe18cf7d15093 406 Gene3D G3DSA:3.30.9.50 46 278 1.2E-57 T 12-10-2018 TL08_20990 743b96b5f3cf745bb03a082c67ff68fa 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.7E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20990 743b96b5f3cf745bb03a082c67ff68fa 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.7E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20990 743b96b5f3cf745bb03a082c67ff68fa 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.7E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20990 743b96b5f3cf745bb03a082c67ff68fa 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.7E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20990 743b96b5f3cf745bb03a082c67ff68fa 249 SUPERFAMILY SSF51735 4 245 9.52E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_20990 743b96b5f3cf745bb03a082c67ff68fa 249 Gene3D G3DSA:3.40.50.720 1 248 1.4E-43 T 12-10-2018 TL08_20990 743b96b5f3cf745bb03a082c67ff68fa 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 2.9E-37 T 12-10-2018 TL08_10170 7e1e86a1cdb29996c0f52379e45a6c77 441 SUPERFAMILY SSF47413 40 94 4.44E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_10170 7e1e86a1cdb29996c0f52379e45a6c77 441 SMART SM00530 45 100 5.6E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_10170 7e1e86a1cdb29996c0f52379e45a6c77 441 Pfam PF13560 Helix-turn-helix domain 41 102 6.5E-12 T 12-10-2018 TL08_10170 7e1e86a1cdb29996c0f52379e45a6c77 441 Gene3D G3DSA:1.10.260.40 24 101 2.9E-7 T 12-10-2018 TL08_10170 7e1e86a1cdb29996c0f52379e45a6c77 441 Gene3D G3DSA:1.25.40.10 216 439 1.2E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_01870 9b73318aadd3f7580f5a7cd0eea6a58b 319 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 76 316 5.6E-63 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 TL08_01870 9b73318aadd3f7580f5a7cd0eea6a58b 319 Gene3D G3DSA:3.30.1330.30 65 148 2.1E-9 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_01870 9b73318aadd3f7580f5a7cd0eea6a58b 319 SUPERFAMILY SSF75217 140 317 4.32E-43 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TL08_01870 9b73318aadd3f7580f5a7cd0eea6a58b 319 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 77 151 1.5E-16 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TL08_01870 9b73318aadd3f7580f5a7cd0eea6a58b 319 Pfam PF00588 SpoU rRNA Methylase family 169 309 8.4E-36 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TL08_01870 9b73318aadd3f7580f5a7cd0eea6a58b 319 Gene3D G3DSA:3.40.1280.10 153 317 2.7E-51 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TL08_01870 9b73318aadd3f7580f5a7cd0eea6a58b 319 SMART SM00967 76 152 1.6E-16 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TL08_01870 9b73318aadd3f7580f5a7cd0eea6a58b 319 SUPERFAMILY SSF55315 72 149 2.0E-15 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 485 832 2.3E-152 T 12-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 55 384 8.0E-143 T 12-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 SMART SM00729 58 292 1.2E-5 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 SMART SM00729 521 750 0.0026 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 Pfam PF04055 Radical SAM superfamily 62 239 3.5E-11 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 SUPERFAMILY SSF102114 487 820 2.75E-46 T 12-10-2018 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 Hamap MF_01611 FO synthase subunit 1 [cofG]. 54 386 49.395 T 12-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 Pfam PF04055 Radical SAM superfamily 525 696 2.2E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 Gene3D G3DSA:3.20.20.70 479 834 1.3E-48 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 Gene3D G3DSA:3.20.20.70 1 303 2.7E-50 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 SUPERFAMILY SSF102114 56 356 1.26E-38 T 12-10-2018 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 Hamap MF_01612 FO synthase subunit 2 [cofH]. 460 833 48.686 T 12-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 TL08_13605 ad7fa034ec300f294382ac622bb01c96 844 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 517 829 3.0E-109 T 12-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.2E-20 T 12-10-2018 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.2E-20 T 12-10-2018 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.2E-20 T 12-10-2018 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.2E-20 T 12-10-2018 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.2E-20 T 12-10-2018 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 Pfam PF14759 Reductase C-terminal 337 406 3.7E-14 T 12-10-2018 IPR028202 Reductase, C-terminal TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 Gene3D G3DSA:3.30.390.30 337 409 7.5E-15 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 SUPERFAMILY SSF51905 143 310 3.46E-23 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 SUPERFAMILY SSF51905 3 187 2.52E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 5.5E-16 T 12-10-2018 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 5.5E-16 T 12-10-2018 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 5.5E-16 T 12-10-2018 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 5.5E-16 T 12-10-2018 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 SUPERFAMILY SSF55424 333 406 7.69E-20 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 302 2.4E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 Gene3D G3DSA:3.50.50.60 4 302 7.3E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06765 58a9aef873e26d6d976201ac4c018e2a 410 Gene3D G3DSA:3.50.50.60 113 240 7.3E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_19945 de04821199931110e42445d16d602e6b 403 Pfam PF00107 Zinc-binding dehydrogenase 190 259 3.8E-11 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_19945 de04821199931110e42445d16d602e6b 403 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_19945 de04821199931110e42445d16d602e6b 403 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 3.5E-10 T 12-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated TL08_19945 de04821199931110e42445d16d602e6b 403 SUPERFAMILY SSF50129 1 194 6.13E-55 T 12-10-2018 IPR011032 GroES-like superfamily TL08_19945 de04821199931110e42445d16d602e6b 403 SUPERFAMILY SSF51735 156 363 6.47E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19945 de04821199931110e42445d16d602e6b 403 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 143 2.3E-25 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_19945 de04821199931110e42445d16d602e6b 403 SMART SM00829 8 323 7.2E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_19945 de04821199931110e42445d16d602e6b 403 Gene3D G3DSA:3.90.180.10 4 390 4.1E-108 T 12-10-2018 TL08_19945 de04821199931110e42445d16d602e6b 403 Gene3D G3DSA:3.40.50.720 169 362 4.1E-108 T 12-10-2018 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 Pfam PF00288 GHMP kinases N terminal domain 81 140 2.4E-10 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 SUPERFAMILY SSF55060 164 264 5.76E-20 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 TIGRFAM TIGR00191 thrB: homoserine kinase 4 264 3.9E-55 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 PIRSF PIRSF000676 1 272 2.2E-68 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 PRINTS PR00958 Homoserine kinase signature 94 109 8.8E-32 T 12-10-2018 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 PRINTS PR00958 Homoserine kinase signature 11 26 8.8E-32 T 12-10-2018 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 PRINTS PR00958 Homoserine kinase signature 127 140 8.8E-32 T 12-10-2018 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 PRINTS PR00958 Homoserine kinase signature 245 260 8.8E-32 T 12-10-2018 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 PRINTS PR00958 Homoserine kinase signature 168 185 8.8E-32 T 12-10-2018 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 Hamap MF_00384 Homoserine kinase [thrB]. 6 290 26.909 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 87 98 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 Gene3D G3DSA:3.30.230.10 6 160 1.1E-70 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 SUPERFAMILY SSF54211 4 148 1.06E-26 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_07250 c2c40abf7f0bebdab956d9200eba31f9 292 Gene3D G3DSA:3.30.70.890 161 260 1.1E-70 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TL08_02335 b960d12ff414714a1475af9d4e2e3f87 349 SUPERFAMILY SSF69593 81 337 1.44E-32 T 12-10-2018 TL08_02335 b960d12ff414714a1475af9d4e2e3f87 349 Pfam PF01553 Acyltransferase 121 251 8.6E-16 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_02335 b960d12ff414714a1475af9d4e2e3f87 349 SMART SM00563 135 254 8.3E-15 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_02335 b960d12ff414714a1475af9d4e2e3f87 349 PIRSF PIRSF016753 40 349 1.1E-99 T 12-10-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted TL08_06425 84dbc70071de6225888e0f9284b33aae 594 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 37 480 1.8E-148 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 3.1E-96 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 Gene3D G3DSA:1.20.210.10 16 541 1.5E-204 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 SUPERFAMILY SSF81442 26 535 4.06E-175 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_06425 84dbc70071de6225888e0f9284b33aae 594 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 1.0E-215 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TL08_12520 9258eabc6b7da608785c78f374bd581d 137 SUPERFAMILY SSF50475 28 134 4.58E-10 T 12-10-2018 TL08_12520 9258eabc6b7da608785c78f374bd581d 137 Gene3D G3DSA:2.30.110.10 1 135 9.2E-48 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_12520 9258eabc6b7da608785c78f374bd581d 137 Pfam PF04075 F420H(2)-dependent quinone reductase 11 134 8.8E-38 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_12520 9258eabc6b7da608785c78f374bd581d 137 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 21 133 9.9E-29 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_01915 eb3c1d6e954b857cea63fc3ee3b2fd1a 274 SUPERFAMILY SSF52540 10 236 4.87E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01915 eb3c1d6e954b857cea63fc3ee3b2fd1a 274 SMART SM00382 35 222 5.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01915 eb3c1d6e954b857cea63fc3ee3b2fd1a 274 Pfam PF00005 ABC transporter 27 172 1.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_01915 eb3c1d6e954b857cea63fc3ee3b2fd1a 274 Gene3D G3DSA:3.40.50.300 2 256 3.4E-59 T 12-10-2018 TL08_01915 eb3c1d6e954b857cea63fc3ee3b2fd1a 274 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_24210 2399e15bccc286c7c2ec4d3ef4889fba 311 Pfam PF13560 Helix-turn-helix domain 37 101 1.1E-11 T 12-10-2018 TL08_24210 2399e15bccc286c7c2ec4d3ef4889fba 311 Gene3D G3DSA:1.10.260.40 28 102 5.4E-9 T 12-10-2018 TL08_24210 2399e15bccc286c7c2ec4d3ef4889fba 311 SUPERFAMILY SSF47413 33 95 1.93E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_24210 2399e15bccc286c7c2ec4d3ef4889fba 311 SMART SM00530 41 98 2.1E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_11565 22200c823a5b81049895da4c78ef439e 309 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 1.3E-18 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TL08_11565 22200c823a5b81049895da4c78ef439e 309 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 30.352 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 TL08_11565 22200c823a5b81049895da4c78ef439e 309 Gene3D G3DSA:3.10.25.10 208 307 1.2E-18 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TL08_11565 22200c823a5b81049895da4c78ef439e 309 SUPERFAMILY SSF50486 206 305 3.92E-23 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 TL08_11565 22200c823a5b81049895da4c78ef439e 309 Gene3D G3DSA:3.40.50.170 1 206 1.8E-60 T 12-10-2018 TL08_11565 22200c823a5b81049895da4c78ef439e 309 Pfam PF00551 Formyl transferase 4 178 2.1E-27 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TL08_11565 22200c823a5b81049895da4c78ef439e 309 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 303 9.7E-61 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 TL08_11565 22200c823a5b81049895da4c78ef439e 309 SUPERFAMILY SSF53328 1 204 6.54E-53 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 Gene3D G3DSA:1.10.10.10 864 917 7.4E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 SUPERFAMILY SSF46894 852 915 2.48E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 SMART SM00421 857 914 7.9E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 Pfam PF00196 Bacterial regulatory proteins, luxR family 859 909 4.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 890 902 6.9E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 874 890 6.9E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 860 874 6.9E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 Gene3D G3DSA:1.25.40.10 525 863 5.3E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 ProSitePatterns PS00622 LuxR-type HTH domain signature. 874 901 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 SUPERFAMILY SSF52540 6 234 1.75E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_15950 621ccd01bbcaf97ee1118c6f22a59781 926 Pfam PF13191 AAA ATPase domain 4 159 7.4E-15 T 12-10-2018 TL08_14685 81f2379313b4d69e21d1dd7d13d12f9f 126 Pfam PF02810 SEC-C motif 1 19 6.7E-6 T 12-10-2018 IPR004027 SEC-C motif TL08_14685 81f2379313b4d69e21d1dd7d13d12f9f 126 Gene3D G3DSA:3.10.450.50 3 126 1.2E-36 T 12-10-2018 TL08_14685 81f2379313b4d69e21d1dd7d13d12f9f 126 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 1 124 27.039 T 12-10-2018 IPR023006 Uncharacterised protein family UPF0225 TL08_14685 81f2379313b4d69e21d1dd7d13d12f9f 126 SUPERFAMILY SSF54427 26 125 8.76E-32 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_08495 d41fd70ec95d85250e729f39e6a71028 211 SUPERFAMILY SSF51569 4 208 2.2E-67 T 12-10-2018 TL08_08495 d41fd70ec95d85250e729f39e6a71028 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 208 2.5E-77 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TL08_08495 d41fd70ec95d85250e729f39e6a71028 211 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 12-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TL08_08495 d41fd70ec95d85250e729f39e6a71028 211 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 12-10-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TL08_08495 d41fd70ec95d85250e729f39e6a71028 211 Gene3D G3DSA:3.20.20.70 1 210 1.1E-73 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_08495 d41fd70ec95d85250e729f39e6a71028 211 Pfam PF01081 KDPG and KHG aldolase 14 201 2.2E-69 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TL08_26200 05473aee20a8017e03f03592c02dad20 306 Pfam PF06197 Protein of unknown function (DUF998) 35 228 1.6E-14 T 12-10-2018 IPR009339 Protein of unknown function DUF998 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 SUPERFAMILY SSF48179 196 290 2.21E-27 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 SMART SM00984 316 417 1.8E-38 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 Gene3D G3DSA:3.40.50.720 2 196 1.8E-58 T 12-10-2018 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 SUPERFAMILY SSF52413 307 426 5.1E-31 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 PIRSF PIRSF000124 3 432 1.4E-115 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 Gene3D G3DSA:1.20.5.100 197 226 3.0E-12 T 12-10-2018 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 288 2.1E-32 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 SUPERFAMILY SSF51735 6 183 5.15E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 416 9.5E-28 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 Gene3D G3DSA:3.40.50.720 227 437 7.9E-66 T 12-10-2018 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 174 1.6E-47 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 413 1.2E-118 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TL08_19600 8606668ae9b4711c002fbb34baf0dbef 438 PIRSF PIRSF500134 3 435 7.1E-135 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 TL08_18370 9d0e03de61b438475c737750dce8992e 258 Gene3D G3DSA:2.60.120.10 15 132 7.6E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_18370 9d0e03de61b438475c737750dce8992e 258 SUPERFAMILY SSF51182 14 146 2.76E-13 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_18370 9d0e03de61b438475c737750dce8992e 258 Pfam PF07883 Cupin domain 39 98 1.7E-6 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TL08_08455 8e93a5db15845705e53847370b0de271 217 Gene3D G3DSA:3.40.50.2300 1 97 9.1E-26 T 12-10-2018 TL08_08455 8e93a5db15845705e53847370b0de271 217 Pfam PF00072 Response regulator receiver domain 2 89 7.5E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_08455 8e93a5db15845705e53847370b0de271 217 SUPERFAMILY SSF52172 3 147 6.96E-28 T 12-10-2018 IPR011006 CheY-like superfamily TL08_08455 8e93a5db15845705e53847370b0de271 217 Gene3D G3DSA:1.10.10.10 100 205 7.7E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08455 8e93a5db15845705e53847370b0de271 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 122 192 2.5E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_08455 8e93a5db15845705e53847370b0de271 217 SMART SM00448 1 88 8.0E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_08455 8e93a5db15845705e53847370b0de271 217 SMART SM00862 121 193 9.7E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_22000 299a30c6eb9ae9ca91c7482797de977e 296 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 35 295 42.48 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TL08_22000 299a30c6eb9ae9ca91c7482797de977e 296 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 36 296 7.8E-91 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TL08_22000 299a30c6eb9ae9ca91c7482797de977e 296 PIRSF PIRSF000388 26 296 1.3E-108 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TL08_22000 299a30c6eb9ae9ca91c7482797de977e 296 SUPERFAMILY SSF51621 34 294 1.69E-102 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TL08_22000 299a30c6eb9ae9ca91c7482797de977e 296 Gene3D G3DSA:3.20.20.60 32 295 8.0E-110 T 12-10-2018 TL08_22000 299a30c6eb9ae9ca91c7482797de977e 296 Pfam PF02548 Ketopantoate hydroxymethyltransferase 34 290 2.0E-107 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TL08_18160 64bcdde6bd9936f188811dce5c1832ef 389 Gene3D G3DSA:3.30.930.10 59 387 1.8E-100 T 12-10-2018 TL08_18160 64bcdde6bd9936f188811dce5c1832ef 389 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 59 385 43.484 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 TL08_18160 64bcdde6bd9936f188811dce5c1832ef 389 SUPERFAMILY SSF46589 65 149 1.73E-14 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TL08_18160 64bcdde6bd9936f188811dce5c1832ef 389 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 71 138 2.9E-16 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TL08_18160 64bcdde6bd9936f188811dce5c1832ef 389 SUPERFAMILY SSF55681 143 382 5.39E-71 T 12-10-2018 TL08_18160 64bcdde6bd9936f188811dce5c1832ef 389 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 104 381 2.8E-84 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TL08_18160 64bcdde6bd9936f188811dce5c1832ef 389 Pfam PF01409 tRNA synthetases class II core domain (F) 143 382 1.8E-95 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TL08_10055 18d6f35f3786955af01fead727fc4655 384 Gene3D G3DSA:2.40.10.10 270 369 7.0E-72 T 12-10-2018 TL08_10055 18d6f35f3786955af01fead727fc4655 384 Gene3D G3DSA:3.30.300.50 119 189 5.3E-10 T 12-10-2018 IPR035070 Streptogrisin prodomain TL08_10055 18d6f35f3786955af01fead727fc4655 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 304 321 1.1E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_10055 18d6f35f3786955af01fead727fc4655 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 222 236 1.1E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_10055 18d6f35f3786955af01fead727fc4655 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 323 346 1.1E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_10055 18d6f35f3786955af01fead727fc4655 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 283 303 1.1E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_10055 18d6f35f3786955af01fead727fc4655 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 347 361 1.1E-44 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_10055 18d6f35f3786955af01fead727fc4655 384 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 332 343 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site TL08_10055 18d6f35f3786955af01fead727fc4655 384 Gene3D G3DSA:3.30.300.50 36 118 1.3E-7 T 12-10-2018 IPR035070 Streptogrisin prodomain TL08_10055 18d6f35f3786955af01fead727fc4655 384 SUPERFAMILY SSF50494 205 375 2.05E-35 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_10055 18d6f35f3786955af01fead727fc4655 384 Gene3D G3DSA:2.40.10.10 201 380 7.0E-72 T 12-10-2018 TL08_10055 18d6f35f3786955af01fead727fc4655 384 PIRSF PIRSF001134 3 384 4.0E-125 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_10055 18d6f35f3786955af01fead727fc4655 384 Pfam PF00089 Trypsin 224 374 3.7E-9 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_10055 18d6f35f3786955af01fead727fc4655 384 Pfam PF02983 Alpha-lytic protease prodomain 120 180 6.3E-13 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 TIGRFAM TIGR00131 gal_kin: galactokinase 23 408 2.7E-80 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 SUPERFAMILY SSF54211 20 229 2.58E-56 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 Gene3D G3DSA:3.30.230.10 37 228 9.1E-118 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 139 150 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 Pfam PF10509 Galactokinase galactose-binding signature 26 72 3.2E-21 T 12-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 Gene3D G3DSA:3.30.70.890 229 384 9.1E-118 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 ProSitePatterns PS00106 Galactokinase signature. 43 54 - T 12-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 Pfam PF08544 GHMP kinases C terminal 316 388 3.4E-11 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 PRINTS PR00959 Mevalonate kinase family signature 41 65 1.9E-40 T 12-10-2018 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 PRINTS PR00959 Mevalonate kinase family signature 189 208 1.9E-40 T 12-10-2018 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 PRINTS PR00959 Mevalonate kinase family signature 137 159 1.9E-40 T 12-10-2018 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 PRINTS PR00959 Mevalonate kinase family signature 356 373 1.9E-40 T 12-10-2018 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 Pfam PF00288 GHMP kinases N terminal domain 133 207 1.1E-14 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 PIRSF PIRSF000530 17 412 1.4E-112 T 12-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 PRINTS PR00473 Galactokinase signature 43 61 9.4E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 PRINTS PR00473 Galactokinase signature 110 121 9.4E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 PRINTS PR00473 Galactokinase signature 130 148 9.4E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 PRINTS PR00473 Galactokinase signature 293 307 9.4E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TL08_08665 4c8ee7156bea1aec87ea57644b8df83e 415 SUPERFAMILY SSF55060 234 408 1.12E-42 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TL08_26060 fbf53a7a0d980f317b88e9585d4cc998 296 ProSitePatterns PS01057 SAICAR synthetase signature 1. 97 111 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_26060 fbf53a7a0d980f317b88e9585d4cc998 296 SUPERFAMILY SSF56104 7 291 2.45E-100 T 12-10-2018 TL08_26060 fbf53a7a0d980f317b88e9585d4cc998 296 Pfam PF01259 SAICAR synthetase 12 260 5.3E-103 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_26060 fbf53a7a0d980f317b88e9585d4cc998 296 ProSitePatterns PS01058 SAICAR synthetase signature 2. 196 204 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_26060 fbf53a7a0d980f317b88e9585d4cc998 296 Gene3D G3DSA:3.30.200.20 2 95 2.8E-31 T 12-10-2018 TL08_26060 fbf53a7a0d980f317b88e9585d4cc998 296 Gene3D G3DSA:3.30.470.20 96 240 1.2E-60 T 12-10-2018 TL08_26060 fbf53a7a0d980f317b88e9585d4cc998 296 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 9 288 26.928 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_26060 fbf53a7a0d980f317b88e9585d4cc998 296 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 12 289 1.0E-74 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TL08_05115 13b6501b847f026bb618b12d9fb42753 386 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 349 356 1.2E-5 T 12-10-2018 TL08_05115 13b6501b847f026bb618b12d9fb42753 386 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.2E-5 T 12-10-2018 TL08_05115 13b6501b847f026bb618b12d9fb42753 386 Gene3D G3DSA:3.90.660.50 79 170 1.8E-14 T 12-10-2018 TL08_05115 13b6501b847f026bb618b12d9fb42753 386 SUPERFAMILY SSF51971 1 378 7.42E-24 T 12-10-2018 TL08_05115 13b6501b847f026bb618b12d9fb42753 386 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 64 2.7E-8 T 12-10-2018 TL08_05115 13b6501b847f026bb618b12d9fb42753 386 Gene3D G3DSA:3.50.50.60 7 207 1.8E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 SUPERFAMILY SSF52540 3 224 2.39E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 Pfam PF00005 ABC transporter 20 175 6.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 ProSitePatterns PS00211 ABC transporters family signature. 384 398 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 Gene3D G3DSA:3.40.50.300 1 246 7.8E-57 T 12-10-2018 TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 Gene3D G3DSA:3.40.50.300 247 462 4.2E-49 T 12-10-2018 TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 SMART SM00382 271 462 6.1E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 SMART SM00382 28 228 9.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 Pfam PF00005 ABC transporter 265 412 7.5E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_14480 dac4a421e7c3a1e1ceffe5ef03db39e0 462 SUPERFAMILY SSF52540 246 461 4.18E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09770 76787eac60c71675be0a792f2950ffa6 246 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 70 242 7.1E-32 T 12-10-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 339 566 4.2E-75 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 SUPERFAMILY SSF52777 327 566 5.19E-79 T 12-10-2018 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 Gene3D G3DSA:2.40.50.100 122 226 1.0E-27 T 12-10-2018 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 Gene3D G3DSA:2.40.50.100 2 101 6.3E-27 T 12-10-2018 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 SUPERFAMILY SSF51230 129 220 1.7E-27 T 12-10-2018 IPR011053 Single hybrid motif TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 Pfam PF00364 Biotin-requiring enzyme 130 201 3.6E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 Pfam PF00364 Biotin-requiring enzyme 5 76 3.1E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 SUPERFAMILY SSF47005 264 308 7.85E-12 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 Gene3D G3DSA:3.30.559.10 319 572 2.1E-84 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 152 181 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 Gene3D G3DSA:4.10.320.10 265 309 1.6E-15 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 Pfam PF02817 e3 binding domain 270 304 3.3E-14 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 575 8.5E-261 T 12-10-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 TL08_21870 6e1f74fb98e8bf896db18e5c91753376 575 SUPERFAMILY SSF51230 1 96 5.63E-27 T 12-10-2018 IPR011053 Single hybrid motif TL08_07115 8829df9d59e1bbac8501b81fe481ca47 222 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 65 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_07115 8829df9d59e1bbac8501b81fe481ca47 222 Gene3D G3DSA:1.10.357.10 79 222 3.3E-23 T 12-10-2018 TL08_07115 8829df9d59e1bbac8501b81fe481ca47 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 2.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_07115 8829df9d59e1bbac8501b81fe481ca47 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 7.3E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_07115 8829df9d59e1bbac8501b81fe481ca47 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 7.3E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_07115 8829df9d59e1bbac8501b81fe481ca47 222 SUPERFAMILY SSF46689 13 88 2.72E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_07115 8829df9d59e1bbac8501b81fe481ca47 222 Gene3D G3DSA:1.10.10.60 11 67 4.7E-16 T 12-10-2018 TL08_09925 c63753e2a835a16d00446684c17dcbf8 141 SUPERFAMILY SSF54909 1 119 6.7E-34 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_09925 c63753e2a835a16d00446684c17dcbf8 141 Gene3D G3DSA:3.30.70.1060 1 118 1.2E-33 T 12-10-2018 TL08_09925 c63753e2a835a16d00446684c17dcbf8 141 Pfam PF03795 YCII-related domain 1 116 1.2E-24 T 12-10-2018 IPR005545 YCII-related TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 4.9E-272 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 Gene3D G3DSA:3.40.50.10730 138 344 5.2E-243 T 12-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 Pfam PF17391 Urocanase N-terminal domain 8 134 3.9E-58 T 12-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 Pfam PF01175 Urocanase Rossmann-like domain 137 344 2.9E-83 T 12-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 PIRSF PIRSF001423 2 552 1.2E-272 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 ProSitePatterns PS01233 Urocanase signature. 437 452 - T 12-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 Hamap MF_00577 Urocanate hydratase [hutU]. 3 551 49.702 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 SUPERFAMILY SSF111326 5 548 6.93E-245 T 12-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 Gene3D G3DSA:3.40.1770.10 16 537 5.2E-243 T 12-10-2018 TL08_23075 4a5c5c061d7047a8fcec4ebe1734eb93 552 Pfam PF17392 Urocanase C-terminal domain 347 541 1.3E-91 T 12-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Gene3D G3DSA:3.40.50.300 576 815 1.0E-227 T 12-10-2018 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SUPERFAMILY SSF52540 387 496 1.06E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SMART SM00490 860 944 3.3E-18 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Gene3D G3DSA:3.30.2060.10 148 235 2.8E-59 T 12-10-2018 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Gene3D G3DSA:2.30.30.840 513 575 1.0E-227 T 12-10-2018 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SMART SM00982 1045 1155 3.4E-32 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 43 1155 27.221 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SUPERFAMILY SSF52540 560 817 5.43E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SUPERFAMILY SSF141259 502 582 1.96E-18 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Gene3D G3DSA:3.40.50.11180 53 315 2.8E-59 T 12-10-2018 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Pfam PF00270 DEAD/DEAH box helicase 659 800 2.1E-16 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Pfam PF03461 TRCF domain 1046 1140 2.3E-17 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SUPERFAMILY SSF52540 816 1023 3.19E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SUPERFAMILY SSF143517 1032 1206 1.09E-28 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Gene3D G3DSA:3.90.1150.50 1041 1168 9.3E-19 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SMART SM01058 509 610 2.2E-48 T 12-10-2018 IPR003711 CarD-like/TRCF domain TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 165 1131 0.0 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SMART SM00487 634 830 4.0E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Pfam PF00271 Helicase conserved C-terminal domain 844 943 4.4E-15 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Pfam PF02559 CarD-like/TRCF domain 510 609 3.8E-31 T 12-10-2018 IPR003711 CarD-like/TRCF domain TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 Gene3D G3DSA:3.40.50.300 510 1022 1.0E-227 T 12-10-2018 TL08_03730 732e18a62d3140d9f85d9b34ca05ea31 1219 SUPERFAMILY SSF52540 27 368 3.98E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01575 5dff3716f0aa20025b04dca32243cc64 185 SUPERFAMILY SSF109604 21 128 2.97E-11 T 12-10-2018 TL08_01575 5dff3716f0aa20025b04dca32243cc64 185 Gene3D G3DSA:1.10.3210.10 16 105 1.2E-5 T 12-10-2018 TL08_01575 5dff3716f0aa20025b04dca32243cc64 185 Pfam PF01966 HD domain 22 95 3.7E-5 T 12-10-2018 IPR006674 HD domain TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 369 9.4E-161 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 Gene3D G3DSA:3.40.50.720 3 353 1.0E-136 T 12-10-2018 TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 137 1.1E-47 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 PIRSF PIRSF000183 1 371 7.0E-158 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.7E-77 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 SMART SM01003 4 137 2.4E-79 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 SUPERFAMILY SSF52283 1 359 4.59E-67 T 12-10-2018 TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 SUPERFAMILY SSF51735 137 303 4.04E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 Gene3D G3DSA:3.40.50.720 130 305 1.0E-136 T 12-10-2018 TL08_22980 06a03cbcfebde6c3a4e72159b1d0b22b 372 SMART SM01002 149 297 6.7E-79 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TL08_05575 b971b003221eea41a73f28d4b056a9c4 310 SUPERFAMILY SSF46785 5 87 1.65E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05575 b971b003221eea41a73f28d4b056a9c4 310 Pfam PF03466 LysR substrate binding domain 96 295 7.7E-15 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_05575 b971b003221eea41a73f28d4b056a9c4 310 Gene3D G3DSA:3.40.190.10 166 270 4.0E-17 T 12-10-2018 TL08_05575 b971b003221eea41a73f28d4b056a9c4 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.7E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_05575 b971b003221eea41a73f28d4b056a9c4 310 Gene3D G3DSA:1.10.10.10 1 87 1.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05575 b971b003221eea41a73f28d4b056a9c4 310 SUPERFAMILY SSF53850 97 299 9.51E-16 T 12-10-2018 TL08_05575 b971b003221eea41a73f28d4b056a9c4 310 Gene3D G3DSA:3.40.190.10 97 288 4.0E-17 T 12-10-2018 TL08_19650 229de2283bafe70949b3b2785518addf 320 SUPERFAMILY SSF52283 11 139 2.13E-27 T 12-10-2018 TL08_19650 229de2283bafe70949b3b2785518addf 320 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 152 179 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TL08_19650 229de2283bafe70949b3b2785518addf 320 Gene3D G3DSA:3.40.50.720 106 289 4.0E-110 T 12-10-2018 TL08_19650 229de2283bafe70949b3b2785518addf 320 Gene3D G3DSA:3.40.50.720 25 310 4.0E-110 T 12-10-2018 TL08_19650 229de2283bafe70949b3b2785518addf 320 SUPERFAMILY SSF51735 106 287 2.97E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19650 229de2283bafe70949b3b2785518addf 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 23 317 6.5E-21 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TL08_19650 229de2283bafe70949b3b2785518addf 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 286 2.9E-49 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TL08_19135 bf7a13b3a00d28b32725927c1e087ef2 222 SUPERFAMILY SSF46689 40 110 6.48E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_19135 bf7a13b3a00d28b32725927c1e087ef2 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 51 88 4.3E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19135 bf7a13b3a00d28b32725927c1e087ef2 222 Gene3D G3DSA:1.10.357.10 32 210 7.2E-27 T 12-10-2018 TL08_19635 accc3dcff7159c3e1c4333e50ac20fde 345 SUPERFAMILY SSF50129 19 145 1.52E-26 T 12-10-2018 IPR011032 GroES-like superfamily TL08_19635 accc3dcff7159c3e1c4333e50ac20fde 345 Gene3D G3DSA:3.40.50.720 131 289 3.3E-78 T 12-10-2018 TL08_19635 accc3dcff7159c3e1c4333e50ac20fde 345 SUPERFAMILY SSF51735 125 262 1.92E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19635 accc3dcff7159c3e1c4333e50ac20fde 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 95 3.8E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_19635 accc3dcff7159c3e1c4333e50ac20fde 345 Pfam PF13602 Zinc-binding dehydrogenase 191 343 1.7E-20 T 12-10-2018 TL08_19635 accc3dcff7159c3e1c4333e50ac20fde 345 Gene3D G3DSA:3.90.180.10 20 339 3.3E-78 T 12-10-2018 TL08_19635 accc3dcff7159c3e1c4333e50ac20fde 345 SMART SM00829 16 343 1.2E-13 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_12525 7ca647ab1306467d468553009e93525d 411 Gene3D G3DSA:1.20.1250.20 238 411 2.4E-17 T 12-10-2018 TL08_12525 7ca647ab1306467d468553009e93525d 411 Gene3D G3DSA:1.20.1250.20 18 237 3.4E-28 T 12-10-2018 TL08_12525 7ca647ab1306467d468553009e93525d 411 Pfam PF07690 Major Facilitator Superfamily 240 403 4.2E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_12525 7ca647ab1306467d468553009e93525d 411 Pfam PF07690 Major Facilitator Superfamily 29 227 5.1E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_12525 7ca647ab1306467d468553009e93525d 411 SUPERFAMILY SSF103473 22 392 1.19E-49 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_12525 7ca647ab1306467d468553009e93525d 411 ProSitePatterns PS00216 Sugar transport proteins signature 1. 274 290 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 PIRSF PIRSF004749 1 167 5.7E-42 T 12-10-2018 IPR023635 Peptide deformylase TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 Hamap MF_00163 Peptide deformylase [def]. 2 160 26.784 T 12-10-2018 IPR023635 Peptide deformylase TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 7 150 2.4E-35 T 12-10-2018 IPR023635 Peptide deformylase TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 PRINTS PR01576 Peptide deformylase signature 87 98 8.4E-30 T 12-10-2018 IPR023635 Peptide deformylase TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 PRINTS PR01576 Peptide deformylase signature 118 147 8.4E-30 T 12-10-2018 IPR023635 Peptide deformylase TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 PRINTS PR01576 Peptide deformylase signature 99 117 8.4E-30 T 12-10-2018 IPR023635 Peptide deformylase TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 PRINTS PR01576 Peptide deformylase signature 33 62 8.4E-30 T 12-10-2018 IPR023635 Peptide deformylase TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 Pfam PF01327 Polypeptide deformylase 4 149 8.1E-42 T 12-10-2018 IPR023635 Peptide deformylase TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 Gene3D G3DSA:3.90.45.10 1 173 1.6E-49 T 12-10-2018 IPR036821 Peptide deformylase superfamily TL08_11570 d3b07e10753ab97723db5b7812b8ae07 179 SUPERFAMILY SSF56420 3 163 3.66E-50 T 12-10-2018 IPR036821 Peptide deformylase superfamily TL08_22680 96bd01f059356f39796d17fcff2ea466 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 4.6E-22 T 12-10-2018 TL08_22680 96bd01f059356f39796d17fcff2ea466 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 4.6E-22 T 12-10-2018 TL08_22680 96bd01f059356f39796d17fcff2ea466 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 4.6E-22 T 12-10-2018 TL08_22680 96bd01f059356f39796d17fcff2ea466 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 4.6E-22 T 12-10-2018 TL08_22680 96bd01f059356f39796d17fcff2ea466 444 SUPERFAMILY SSF51905 14 370 1.0E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_22680 96bd01f059356f39796d17fcff2ea466 444 Pfam PF01494 FAD binding domain 13 346 1.9E-55 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_22680 96bd01f059356f39796d17fcff2ea466 444 Gene3D G3DSA:3.50.50.60 4 191 1.7E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_22680 96bd01f059356f39796d17fcff2ea466 444 Gene3D G3DSA:3.50.50.60 239 372 1.9E-19 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05405 c796af9776fc0871b184b4a974ddda31 459 Gene3D G3DSA:3.20.20.80 54 365 1.6E-120 T 12-10-2018 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 SUPERFAMILY SSF51445 59 357 2.34E-106 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_05405 c796af9776fc0871b184b4a974ddda31 459 PRINTS PR00134 Glycosyl hydrolase family 10 signature 248 260 5.8E-17 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 PRINTS PR00134 Glycosyl hydrolase family 10 signature 131 143 5.8E-17 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 PRINTS PR00134 Glycosyl hydrolase family 10 signature 173 184 5.8E-17 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 PRINTS PR00134 Glycosyl hydrolase family 10 signature 218 229 5.8E-17 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 Gene3D G3DSA:2.60.40.290 370 459 1.1E-20 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 282 292 - T 12-10-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 SUPERFAMILY SSF49384 371 456 1.46E-16 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 Pfam PF00331 Glycosyl hydrolase family 10 58 354 2.2E-109 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 SMART SM00637 373 456 2.0E-12 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TL08_05405 c796af9776fc0871b184b4a974ddda31 459 SMART SM00633 100 356 3.0E-131 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 Gene3D G3DSA:2.40.50.140 1 107 2.3E-32 T 12-10-2018 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 580 2.3E-206 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 SUPERFAMILY SSF50249 2 104 4.0E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_11305 0bf4278c1eaaa862289ded763461332d 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 5.9E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 5.9E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 5.9E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 5.9E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 557 2.2E-98 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 SUPERFAMILY SSF55681 115 583 1.24E-98 T 12-10-2018 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 SUPERFAMILY SSF55261 290 412 1.55E-33 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 Gene3D G3DSA:3.30.930.10 117 580 1.8E-177 T 12-10-2018 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 Gene3D G3DSA:3.30.1360.30 273 412 1.8E-177 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 Pfam PF02938 GAD domain 313 394 1.3E-12 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 584 31.706 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 TL08_11305 0bf4278c1eaaa862289ded763461332d 590 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 3.9E-15 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TL08_04620 bd5308bf4cf9d6f2b9a4a95f8311754c 318 Gene3D G3DSA:1.10.10.10 13 100 6.6E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04620 bd5308bf4cf9d6f2b9a4a95f8311754c 318 SUPERFAMILY SSF53850 98 302 1.41E-41 T 12-10-2018 TL08_04620 bd5308bf4cf9d6f2b9a4a95f8311754c 318 Gene3D G3DSA:3.40.190.290 101 301 1.0E-50 T 12-10-2018 TL08_04620 bd5308bf4cf9d6f2b9a4a95f8311754c 318 Pfam PF03466 LysR substrate binding domain 97 297 3.4E-45 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_04620 bd5308bf4cf9d6f2b9a4a95f8311754c 318 SUPERFAMILY SSF46785 15 120 2.86E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_04620 bd5308bf4cf9d6f2b9a4a95f8311754c 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 72 6.4E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_24485 a42fa9b2163ef5dd0a1202ad4e417a67 405 SUPERFAMILY SSF53659 2 404 7.68E-150 T 12-10-2018 TL08_24485 a42fa9b2163ef5dd0a1202ad4e417a67 405 Gene3D G3DSA:3.40.718.10 1 405 9.0E-215 T 12-10-2018 TL08_24485 a42fa9b2163ef5dd0a1202ad4e417a67 405 PIRSF PIRSF000108 1 405 2.7E-220 T 12-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 TL08_24485 a42fa9b2163ef5dd0a1202ad4e417a67 405 SMART SM01329 9 396 6.4E-138 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TL08_24485 a42fa9b2163ef5dd0a1202ad4e417a67 405 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 404 1.2E-209 T 12-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 TL08_24485 a42fa9b2163ef5dd0a1202ad4e417a67 405 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 389 1.5E-69 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TL08_24485 a42fa9b2163ef5dd0a1202ad4e417a67 405 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 271 290 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 Gene3D G3DSA:1.10.357.20 265 441 3.0E-55 T 12-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 SMART SM00924 25 128 6.7E-24 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 Gene3D G3DSA:1.25.60.10 2 123 6.7E-20 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 SMART SM00116 198 246 4.3E-6 T 12-10-2018 IPR000644 CBS domain TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 SMART SM00116 135 188 3.6 T 12-10-2018 IPR000644 CBS domain TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 Pfam PF01769 Divalent cation transporter 313 434 2.4E-28 T 12-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 SUPERFAMILY SSF158791 5 125 1.7E-23 T 12-10-2018 TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 TIGRFAM TIGR00400 mgtE: magnesium transporter 18 441 4.3E-120 T 12-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 SUPERFAMILY SSF54631 128 264 2.78E-28 T 12-10-2018 TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 SUPERFAMILY SSF161093 270 440 6.93E-49 T 12-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 Pfam PF03448 MgtE intracellular N domain 27 126 5.2E-21 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 Gene3D G3DSA:3.10.580.10 124 250 7.4E-35 T 12-10-2018 TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 Pfam PF00571 CBS domain 199 245 2.2E-7 T 12-10-2018 IPR000644 CBS domain TL08_22175 5bbcf2962aad1e3dbea183c5c9d7ff99 442 Pfam PF00571 CBS domain 128 184 2.9E-7 T 12-10-2018 IPR000644 CBS domain TL08_18720 62a688b16d4abe2733ccf541e1acb54c 571 SUPERFAMILY SSF143975 4 367 5.62E-111 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_18720 62a688b16d4abe2733ccf541e1acb54c 571 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_18720 62a688b16d4abe2733ccf541e1acb54c 571 Pfam PF00920 Dehydratase family 36 553 2.9E-169 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_18720 62a688b16d4abe2733ccf541e1acb54c 571 Gene3D G3DSA:3.50.30.80 371 523 2.1E-50 T 12-10-2018 TL08_18720 62a688b16d4abe2733ccf541e1acb54c 571 SUPERFAMILY SSF52016 371 558 1.1E-55 T 12-10-2018 TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 ProSitePatterns PS00056 Ribosomal protein S17 signature. 65 77 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 14 85 8.9E-33 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 Pfam PF00366 Ribosomal protein S17 19 86 6.7E-29 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 14 89 23.416 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 SUPERFAMILY SSF50249 14 91 4.71E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 14 85 2.0E-28 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 Gene3D G3DSA:2.40.50.140 13 92 2.9E-32 T 12-10-2018 TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 PRINTS PR00973 Ribosomal protein S17 family signature 33 56 3.6E-10 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 PRINTS PR00973 Ribosomal protein S17 family signature 75 82 3.6E-10 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03030 51e4913df3c5acbc58ed70d7bd2b7adb 92 PRINTS PR00973 Ribosomal protein S17 family signature 65 75 3.6E-10 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_24690 7c71682c5e026e9f2da15321f9fba24e 311 SUPERFAMILY SSF46785 15 125 6.12E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_24690 7c71682c5e026e9f2da15321f9fba24e 311 Gene3D G3DSA:3.40.190.10 106 290 8.1E-41 T 12-10-2018 TL08_24690 7c71682c5e026e9f2da15321f9fba24e 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 76 7.6E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_24690 7c71682c5e026e9f2da15321f9fba24e 311 Gene3D G3DSA:3.40.190.10 181 283 8.1E-41 T 12-10-2018 TL08_24690 7c71682c5e026e9f2da15321f9fba24e 311 SUPERFAMILY SSF53850 104 310 6.27E-36 T 12-10-2018 TL08_24690 7c71682c5e026e9f2da15321f9fba24e 311 Pfam PF03466 LysR substrate binding domain 102 309 2.9E-37 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_24690 7c71682c5e026e9f2da15321f9fba24e 311 Gene3D G3DSA:1.10.10.10 15 104 1.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18095 8db64c647eb4354895fbe074798770e8 477 Hamap MF_00006 Argininosuccinate lyase [argH]. 10 462 39.117 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TL08_18095 8db64c647eb4354895fbe074798770e8 477 Gene3D G3DSA:1.20.200.10 116 453 9.7E-131 T 12-10-2018 TL08_18095 8db64c647eb4354895fbe074798770e8 477 SUPERFAMILY SSF48557 14 465 4.4E-132 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 TL08_18095 8db64c647eb4354895fbe074798770e8 477 Gene3D G3DSA:1.10.40.30 371 441 9.7E-131 T 12-10-2018 TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 3.1E-26 T 12-10-2018 IPR000362 Fumarate lyase family TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 3.1E-26 T 12-10-2018 IPR000362 Fumarate lyase family TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 3.1E-26 T 12-10-2018 IPR000362 Fumarate lyase family TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 3.1E-26 T 12-10-2018 IPR000362 Fumarate lyase family TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 5.5E-53 T 12-10-2018 TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 5.5E-53 T 12-10-2018 TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 5.5E-53 T 12-10-2018 TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 5.5E-53 T 12-10-2018 TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 5.5E-53 T 12-10-2018 TL08_18095 8db64c647eb4354895fbe074798770e8 477 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 5.5E-53 T 12-10-2018 TL08_18095 8db64c647eb4354895fbe074798770e8 477 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TL08_18095 8db64c647eb4354895fbe074798770e8 477 Pfam PF00206 Lyase 15 309 4.4E-61 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal TL08_18095 8db64c647eb4354895fbe074798770e8 477 TIGRFAM TIGR00838 argH: argininosuccinate lyase 11 456 2.6E-177 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TL08_18095 8db64c647eb4354895fbe074798770e8 477 Gene3D G3DSA:1.10.275.50 7 115 4.7E-31 T 12-10-2018 TL08_18095 8db64c647eb4354895fbe074798770e8 477 Pfam PF14698 Argininosuccinate lyase C-terminal 372 440 3.4E-23 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TL08_16165 c4d7925e9ad3554e3ef79d42cb5d5da2 380 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 113 138 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TL08_16165 c4d7925e9ad3554e3ef79d42cb5d5da2 380 Pfam PF13378 Enolase C-terminal domain-like 161 363 2.2E-62 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_16165 c4d7925e9ad3554e3ef79d42cb5d5da2 380 Gene3D G3DSA:3.30.390.10 10 364 3.0E-153 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_16165 c4d7925e9ad3554e3ef79d42cb5d5da2 380 SMART SM00922 158 254 4.5E-24 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_16165 c4d7925e9ad3554e3ef79d42cb5d5da2 380 SUPERFAMILY SSF54826 9 139 1.25E-29 T 12-10-2018 TL08_16165 c4d7925e9ad3554e3ef79d42cb5d5da2 380 Gene3D G3DSA:3.20.20.120 131 362 3.0E-153 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_16165 c4d7925e9ad3554e3ef79d42cb5d5da2 380 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 204 235 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TL08_16165 c4d7925e9ad3554e3ef79d42cb5d5da2 380 SUPERFAMILY SSF51604 126 365 7.73E-71 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_16165 c4d7925e9ad3554e3ef79d42cb5d5da2 380 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 41 138 3.1E-15 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TL08_04010 ff44cc2863407de7276949afec3e6c0c 402 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 23 392 8.5E-131 T 12-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 TL08_04010 ff44cc2863407de7276949afec3e6c0c 402 SUPERFAMILY SSF55021 325 371 3.88E-5 T 12-10-2018 TL08_04010 ff44cc2863407de7276949afec3e6c0c 402 Gene3D G3DSA:3.40.50.1100 52 148 3.4E-115 T 12-10-2018 TL08_04010 ff44cc2863407de7276949afec3e6c0c 402 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 44 57 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TL08_04010 ff44cc2863407de7276949afec3e6c0c 402 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 304 4.8E-86 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_04010 ff44cc2863407de7276949afec3e6c0c 402 SUPERFAMILY SSF53686 8 311 1.28E-95 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_04010 ff44cc2863407de7276949afec3e6c0c 402 Gene3D G3DSA:3.40.50.1100 9 308 3.4E-115 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF52151 4596 4856 2.09E-58 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF53901 974 1350 1.63E-98 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00698 Acyl transferase domain 4538 4852 6.4E-44 T 12-10-2018 IPR014043 Acyl transferase TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00698 Acyl transferase domain 3140 3453 1.7E-79 T 12-10-2018 IPR014043 Acyl transferase TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00698 Acyl transferase domain 518 826 5.4E-83 T 12-10-2018 IPR014043 Acyl transferase TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00698 Acyl transferase domain 1497 1765 3.8E-53 T 12-10-2018 IPR014043 Acyl transferase TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF51735 5481 5618 7.89E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2242 2418 4.7E-50 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3729 3909 2.4E-50 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5698 5873 5.8E-51 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4035 4050 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF51735 5696 5946 7.4E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1140 1156 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00823 Phosphopantetheine attachment site 2521 2593 6.6E-26 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00823 Phosphopantetheine attachment site 5976 6048 2.2E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00823 Phosphopantetheine attachment site 887 959 9.3E-27 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00823 Phosphopantetheine attachment site 4008 4080 2.7E-27 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM01294 5977 6044 9.4E-4 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM01294 4013 4076 7.1E-4 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.30.70.3290 3062 3480 4.7E-140 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:1.10.1200.10 3987 4080 3.0E-29 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:1.10.1200.10 2501 2593 8.4E-30 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4254 4270 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF50129 5393 5515 1.57E-26 T 12-10-2018 IPR011032 GroES-like superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF53901 4098 4461 1.67E-96 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF47336 5974 6056 2.75E-20 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:1.10.1200.10 874 961 2.6E-26 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:1.10.1200.10 5958 6051 3.2E-33 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF51735 2240 2455 1.18E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF53901 2614 2986 3.09E-96 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF51735 3724 3966 6.71E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4349 4464 6.2E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1235 1352 7.5E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 380 6.7E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2874 2987 2.1E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF52151 3140 3423 2.51E-56 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.47.10 4087 4517 3.7E-177 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF47336 4004 4115 7.2E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF51735 2053 2228 8.37E-9 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.30.70.3290 4531 4907 7.4E-119 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00826 4927 5085 7.7E-60 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00826 1829 1996 5.4E-53 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.50.11460 5202 5364 1.5E-27 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4599 4865 1.0E-89 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 520 807 9.9E-100 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1498 1781 5.0E-111 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3142 3435 6.6E-104 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.30.70.3290 1420 1826 7.6E-145 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2779 2795 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF52151 1494 1769 1.44E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF47336 886 992 2.36E-20 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF55048 4706 4763 3.79E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF52151 518 799 1.86E-64 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.366.10 1496 1784 7.6E-145 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.366.10 518 810 3.4E-140 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.366.10 4597 4865 7.4E-119 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.366.10 3140 3438 4.7E-140 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.50.720 3492 3979 8.2E-145 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF55048 1620 1683 1.1E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2548 2563 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF47336 2515 2630 1.44E-20 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF51735 3533 3717 8.86E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF53901 8 376 6.2E-91 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 5510 5531 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00829 5383 5688 8.7E-157 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.47.10 2608 3059 2.9E-179 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.47.10 968 1417 3.8E-186 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.47.10 3 444 2.4E-181 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.90.180.10 5368 5692 9.6E-116 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF51735 5200 5367 3.23E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.50.720 5693 5942 3.2E-66 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF14765 Polyketide synthase dehydratase 4927 5193 2.8E-52 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF14765 Polyketide synthase dehydratase 1847 2100 1.4E-43 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1355 1466 4.4E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2992 3109 4.0E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4467 4579 4.8E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 383 497 4.2E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 255 2.2E-81 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4101 4341 1.4E-84 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 977 1227 9.7E-89 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2616 2866 1.5E-83 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00107 Zinc-binding dehydrogenase 5521 5612 2.0E-17 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF55048 3263 3326 9.94E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SUPERFAMILY SSF55048 642 701 6.28E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF08659 KR domain 3729 3907 2.4E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF08659 KR domain 2242 2416 5.7E-51 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF08659 KR domain 5699 5871 7.6E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00550 Phosphopantetheine attachment site 4011 4075 3.6E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00550 Phosphopantetheine attachment site 5978 6044 1.2E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00550 Phosphopantetheine attachment site 2524 2588 4.9E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Pfam PF00550 Phosphopantetheine attachment site 891 955 1.5E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.30.70.3290 450 855 3.4E-140 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00825 Beta-ketoacyl synthase 4103 4517 2.2E-205 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00825 Beta-ketoacyl synthase 12 433 8.0E-196 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00825 Beta-ketoacyl synthase 2618 3041 4.0E-196 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 SMART SM00825 Beta-ketoacyl synthase 979 1405 1.4E-221 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.40.50.720 2110 2475 6.6E-92 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.10.129.110 4916 5197 2.5E-90 T 12-10-2018 TL08_14605 7f8cb622abede2b9b62420ff146f7ec5 6134 Gene3D G3DSA:3.10.129.110 1828 2109 5.9E-78 T 12-10-2018 TL08_13590 177be579aba14f7ced1b5f3681b6564a 319 Pfam PF03180 NLPA lipoprotein 60 294 6.6E-64 T 12-10-2018 IPR004872 Lipoprotein NlpA family TL08_13590 177be579aba14f7ced1b5f3681b6564a 319 Gene3D G3DSA:3.40.190.10 61 283 8.3E-82 T 12-10-2018 TL08_13590 177be579aba14f7ced1b5f3681b6564a 319 Gene3D G3DSA:3.40.190.10 137 246 8.3E-82 T 12-10-2018 TL08_13590 177be579aba14f7ced1b5f3681b6564a 319 SUPERFAMILY SSF53850 60 308 1.26E-65 T 12-10-2018 TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 SUPERFAMILY SSF46785 5 112 2.3E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 Gene3D G3DSA:3.40.190.10 163 255 1.1E-37 T 12-10-2018 TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 Gene3D G3DSA:3.40.190.10 97 261 1.1E-37 T 12-10-2018 TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 SUPERFAMILY SSF53850 91 281 5.74E-27 T 12-10-2018 TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 Gene3D G3DSA:1.10.10.10 1 88 1.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 Pfam PF03466 LysR substrate binding domain 95 272 1.0E-26 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_16640 ca92c8f648d682aa9d67caad97c4dc58 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 4.1E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_02770 4c1193661f8b2584ba15950b7702e2e1 181 Pfam PF13521 AAA domain 9 172 1.3E-41 T 12-10-2018 IPR038727 NadR/Ttd14, AAA domain TL08_02770 4c1193661f8b2584ba15950b7702e2e1 181 Gene3D G3DSA:3.40.50.300 2 47 2.3E-5 T 12-10-2018 TL08_02770 4c1193661f8b2584ba15950b7702e2e1 181 SUPERFAMILY SSF52540 5 176 1.14E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14120 cb9332fad80ea727a8a59d0a2e71e506 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 3.5E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14120 cb9332fad80ea727a8a59d0a2e71e506 193 SUPERFAMILY SSF48498 121 163 5.48E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_14120 cb9332fad80ea727a8a59d0a2e71e506 193 Gene3D G3DSA:1.10.357.10 3 192 3.2E-54 T 12-10-2018 TL08_14120 cb9332fad80ea727a8a59d0a2e71e506 193 SUPERFAMILY SSF46689 14 79 6.48E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_17855 5a714d2b19d6a49bb60d3656e0e406ef 323 SUPERFAMILY SSF54637 155 320 5.19E-50 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_17855 5a714d2b19d6a49bb60d3656e0e406ef 323 Pfam PF13622 Thioesterase-like superfamily 69 319 2.7E-60 T 12-10-2018 TL08_17855 5a714d2b19d6a49bb60d3656e0e406ef 323 Gene3D G3DSA:3.10.129.90 41 323 2.2E-105 T 12-10-2018 TL08_17855 5a714d2b19d6a49bb60d3656e0e406ef 323 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 51 320 4.3E-92 T 12-10-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 TL08_17855 5a714d2b19d6a49bb60d3656e0e406ef 323 SUPERFAMILY SSF54637 44 153 2.14E-41 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 Pfam PF01628 HrcA protein C terminal domain 104 323 6.2E-62 T 12-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 Gene3D G3DSA:3.30.390.60 128 229 4.9E-38 T 12-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 Pfam PF08220 DeoR-like helix-turn-helix domain 17 63 4.2E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 Gene3D G3DSA:1.10.10.10 1 85 2.8E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 336 6.7E-94 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 2 330 27.504 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 PIRSF PIRSF005485 1 340 8.6E-101 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 SUPERFAMILY SSF55781 72 338 4.51E-56 T 12-10-2018 TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 Gene3D G3DSA:3.30.450.40 105 335 4.9E-38 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_21405 35706b5340ae7459c3436d61dd2fbd7a 340 SUPERFAMILY SSF46785 4 83 3.1E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23925 3f4ce55ab36e1cbd053b683fac2c578d 117 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 43 99 1.8E-8 T 12-10-2018 IPR026496 Putative ATP-grasp target RiPP TL08_02625 7afbc26f06016abe3514b947b873b1f0 275 Gene3D G3DSA:1.10.10.1590 45 115 1.2E-20 T 12-10-2018 TL08_02625 7afbc26f06016abe3514b947b873b1f0 275 PIRSF PIRSF000216 4 260 1.5E-61 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02625 7afbc26f06016abe3514b947b873b1f0 275 SUPERFAMILY SSF52833 50 209 1.34E-43 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_02625 7afbc26f06016abe3514b947b873b1f0 275 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 55 201 6.8E-45 T 12-10-2018 TL08_02625 7afbc26f06016abe3514b947b873b1f0 275 Gene3D G3DSA:3.40.30.10 116 220 4.1E-21 T 12-10-2018 TL08_15550 c401b7b83127647fb6ce8a89540b65be 113 PIRSF PIRSF000077 1 104 3.6E-26 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TL08_15550 c401b7b83127647fb6ce8a89540b65be 113 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TL08_15550 c401b7b83127647fb6ce8a89540b65be 113 PRINTS PR00421 Thioredoxin family signature 29 38 3.7E-8 T 12-10-2018 TL08_15550 c401b7b83127647fb6ce8a89540b65be 113 PRINTS PR00421 Thioredoxin family signature 21 29 3.7E-8 T 12-10-2018 TL08_15550 c401b7b83127647fb6ce8a89540b65be 113 PRINTS PR00421 Thioredoxin family signature 68 79 3.7E-8 T 12-10-2018 TL08_15550 c401b7b83127647fb6ce8a89540b65be 113 Gene3D G3DSA:3.40.30.10 1 113 7.1E-29 T 12-10-2018 TL08_15550 c401b7b83127647fb6ce8a89540b65be 113 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 2.0E-30 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TL08_15550 c401b7b83127647fb6ce8a89540b65be 113 SUPERFAMILY SSF52833 4 103 1.22E-31 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_15550 c401b7b83127647fb6ce8a89540b65be 113 Pfam PF00085 Thioredoxin 4 102 9.5E-25 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 TL08_16375 a930d06faf73888716405b1e566a9bfa 342 SUPERFAMILY SSF51197 27 331 9.62E-50 T 12-10-2018 TL08_16375 a930d06faf73888716405b1e566a9bfa 342 Gene3D G3DSA:3.60.130.10 2 342 8.2E-99 T 12-10-2018 TL08_16375 a930d06faf73888716405b1e566a9bfa 342 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 132 320 6.9E-13 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 TL08_16375 a930d06faf73888716405b1e566a9bfa 342 PIRSF PIRSF019543 2 342 2.0E-117 T 12-10-2018 IPR014503 Clavaminate synthase-like GO:0005506|GO:0016491|GO:0055114 TL08_18295 01d701a1bd4486744ace5dd77f04e6d4 290 Gene3D G3DSA:1.10.260.40 1 81 5.4E-10 T 12-10-2018 TL08_18295 01d701a1bd4486744ace5dd77f04e6d4 290 SUPERFAMILY SSF47413 13 69 2.62E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_18295 01d701a1bd4486744ace5dd77f04e6d4 290 Pfam PF13560 Helix-turn-helix domain 12 73 1.7E-10 T 12-10-2018 TL08_18295 01d701a1bd4486744ace5dd77f04e6d4 290 SMART SM00530 16 71 4.6E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_13745 ba436a72776cb2d8ffe885781968f0cf 354 SMART SM00829 16 350 3.5E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_13745 ba436a72776cb2d8ffe885781968f0cf 354 Gene3D G3DSA:3.40.50.720 162 297 2.2E-81 T 12-10-2018 TL08_13745 ba436a72776cb2d8ffe885781968f0cf 354 SUPERFAMILY SSF51735 148 316 2.85E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_13745 ba436a72776cb2d8ffe885781968f0cf 354 Gene3D G3DSA:3.90.180.10 18 336 2.2E-81 T 12-10-2018 TL08_13745 ba436a72776cb2d8ffe885781968f0cf 354 Pfam PF00107 Zinc-binding dehydrogenase 185 312 6.4E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_13745 ba436a72776cb2d8ffe885781968f0cf 354 SUPERFAMILY SSF50129 11 184 1.0E-37 T 12-10-2018 IPR011032 GroES-like superfamily TL08_13745 ba436a72776cb2d8ffe885781968f0cf 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 144 2.9E-24 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_23960 29c150ba6a7c60582d56b360df31066d 407 Gene3D G3DSA:1.10.10.10 15 85 2.5E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23960 29c150ba6a7c60582d56b360df31066d 407 SUPERFAMILY SSF46785 22 84 8.73E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23960 29c150ba6a7c60582d56b360df31066d 407 Pfam PF00480 ROK family 92 397 4.0E-58 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_23960 29c150ba6a7c60582d56b360df31066d 407 SUPERFAMILY SSF53067 91 397 6.98E-59 T 12-10-2018 TL08_23960 29c150ba6a7c60582d56b360df31066d 407 ProSitePatterns PS01125 ROK family signature. 222 249 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_23960 29c150ba6a7c60582d56b360df31066d 407 Gene3D G3DSA:3.30.420.40 96 395 6.6E-89 T 12-10-2018 TL08_23960 29c150ba6a7c60582d56b360df31066d 407 Gene3D G3DSA:3.30.420.40 212 385 6.6E-89 T 12-10-2018 TL08_13650 04c6efa7b7d41b393b6af507d6527dbd 347 Gene3D G3DSA:3.40.50.2300 164 341 1.0E-48 T 12-10-2018 TL08_13650 04c6efa7b7d41b393b6af507d6527dbd 347 SUPERFAMILY SSF47413 12 70 7.15E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_13650 04c6efa7b7d41b393b6af507d6527dbd 347 Gene3D G3DSA:1.10.260.40 5 69 6.9E-23 T 12-10-2018 TL08_13650 04c6efa7b7d41b393b6af507d6527dbd 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 12-10-2018 TL08_13650 04c6efa7b7d41b393b6af507d6527dbd 347 SMART SM00354 12 82 2.5E-24 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_13650 04c6efa7b7d41b393b6af507d6527dbd 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 2.6E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_13650 04c6efa7b7d41b393b6af507d6527dbd 347 SUPERFAMILY SSF53822 72 341 3.39E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_13650 04c6efa7b7d41b393b6af507d6527dbd 347 Pfam PF13377 Periplasmic binding protein-like domain 178 339 5.7E-34 T 12-10-2018 TL08_13650 04c6efa7b7d41b393b6af507d6527dbd 347 Gene3D G3DSA:3.40.50.2300 70 157 1.5E-13 T 12-10-2018 TL08_23085 fea7befc31aab72197881a52ad3fad7c 264 Pfam PF01614 Bacterial transcriptional regulator 127 253 6.3E-16 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_23085 fea7befc31aab72197881a52ad3fad7c 264 Gene3D G3DSA:3.30.450.40 83 261 1.2E-39 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_23085 fea7befc31aab72197881a52ad3fad7c 264 SUPERFAMILY SSF46785 7 80 9.63E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23085 fea7befc31aab72197881a52ad3fad7c 264 SUPERFAMILY SSF55781 72 258 4.19E-39 T 12-10-2018 TL08_23085 fea7befc31aab72197881a52ad3fad7c 264 Gene3D G3DSA:1.10.10.10 5 81 3.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23085 fea7befc31aab72197881a52ad3fad7c 264 Pfam PF09339 IclR helix-turn-helix domain 9 57 8.0E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_23085 fea7befc31aab72197881a52ad3fad7c 264 SMART SM00346 7 97 2.4E-18 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_18995 cc18335d57d98e3ffb631282a915cd13 332 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_18995 cc18335d57d98e3ffb631282a915cd13 332 SMART SM00382 29 212 2.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_18995 cc18335d57d98e3ffb631282a915cd13 332 Pfam PF00005 ABC transporter 21 163 1.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_18995 cc18335d57d98e3ffb631282a915cd13 332 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 2.8E-7 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 TL08_18995 cc18335d57d98e3ffb631282a915cd13 332 Gene3D G3DSA:3.40.50.300 1 245 2.0E-67 T 12-10-2018 TL08_18995 cc18335d57d98e3ffb631282a915cd13 332 SUPERFAMILY SSF52540 5 225 7.5E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18995 cc18335d57d98e3ffb631282a915cd13 332 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 3.3E-107 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TL08_05040 534bf6da829422c3244e34f12dc1b918 172 SUPERFAMILY SSF54637 13 162 4.25E-25 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_05040 534bf6da829422c3244e34f12dc1b918 172 Pfam PF07977 FabA-like domain 33 154 2.3E-8 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TL08_05040 534bf6da829422c3244e34f12dc1b918 172 Gene3D G3DSA:3.10.129.10 20 165 1.0E-29 T 12-10-2018 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 SUPERFAMILY SSF48264 18 412 2.62E-89 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00385 P450 superfamily signature 251 268 2.2E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00385 P450 superfamily signature 353 362 2.2E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00385 P450 superfamily signature 362 373 2.2E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00385 P450 superfamily signature 286 297 2.2E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 Gene3D G3DSA:1.10.630.10 15 412 5.1E-122 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 355 364 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00359 B-class P450 signature 362 373 2.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00359 B-class P450 signature 332 347 2.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00359 B-class P450 signature 304 331 2.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00359 B-class P450 signature 161 176 2.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00359 B-class P450 signature 97 108 2.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00359 B-class P450 signature 286 297 2.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00359 B-class P450 signature 144 160 2.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 PRINTS PR00359 B-class P450 signature 353 362 2.0E-51 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 Pfam PF00067 Cytochrome P450 287 376 1.4E-13 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07160 8af86d856d3ee1fa9138e5a34c0d5228 412 Pfam PF00067 Cytochrome P450 194 277 1.1E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_12780 beacca28abd7f7eb086bd25def560f72 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 310 2.3E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_12780 beacca28abd7f7eb086bd25def560f72 315 SUPERFAMILY SSF161098 97 296 1.83E-12 T 12-10-2018 IPR035906 MetI-like superfamily TL08_12780 beacca28abd7f7eb086bd25def560f72 315 Gene3D G3DSA:1.10.3720.10 91 303 1.4E-15 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 Pfam PF00574 Clp protease 23 197 1.1E-77 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 Gene3D G3DSA:3.90.226.10 2 200 4.5E-72 T 12-10-2018 TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 8 198 39.694 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 117 130 - T 12-10-2018 IPR033135 ClpP, histidine active site TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 SUPERFAMILY SSF52096 24 199 6.4E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 PRINTS PR00127 Clp protease catalytic subunit P signature 173 192 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 PRINTS PR00127 Clp protease catalytic subunit P signature 24 39 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 PRINTS PR00127 Clp protease catalytic subunit P signature 64 84 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 PRINTS PR00127 Clp protease catalytic subunit P signature 95 112 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08050 52ffe859cc4afb8d62a80db540ab2fa0 210 PRINTS PR00127 Clp protease catalytic subunit P signature 116 135 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 Pfam PF00561 alpha/beta hydrolase fold 40 282 8.9E-26 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 PRINTS PR00111 Alpha/beta hydrolase fold signature 66 81 2.8E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 PRINTS PR00111 Alpha/beta hydrolase fold signature 240 254 2.8E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 2.8E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 PRINTS PR00412 Epoxide hydrolase signature 66 81 5.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 PRINTS PR00412 Epoxide hydrolase signature 238 254 5.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 PRINTS PR00412 Epoxide hydrolase signature 271 293 5.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 PRINTS PR00412 Epoxide hydrolase signature 124 137 5.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 SUPERFAMILY SSF53474 12 296 1.77E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16520 b9307e9fc9e7d7921810d862bab07384 300 Gene3D G3DSA:3.40.50.1820 5 299 1.0E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_01685 9e3d7af9a40462eecc4c0c6f82f5f8a1 169 SUPERFAMILY SSF55083 1 151 2.75E-46 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TL08_01685 9e3d7af9a40462eecc4c0c6f82f5f8a1 169 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 84 95 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TL08_01685 9e3d7af9a40462eecc4c0c6f82f5f8a1 169 Gene3D G3DSA:3.30.70.560 1 161 1.9E-44 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TL08_01685 9e3d7af9a40462eecc4c0c6f82f5f8a1 169 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 129 4.8E-37 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TL08_01685 9e3d7af9a40462eecc4c0c6f82f5f8a1 169 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 129 9.2E-31 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TL08_24415 bc3f047cceb20b6858bf5e2267f185fd 549 SUPERFAMILY SSF52540 264 498 7.01E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24415 bc3f047cceb20b6858bf5e2267f185fd 549 Pfam PF00005 ABC transporter 33 177 5.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_24415 bc3f047cceb20b6858bf5e2267f185fd 549 Pfam PF00005 ABC transporter 282 438 1.9E-11 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_24415 bc3f047cceb20b6858bf5e2267f185fd 549 Gene3D G3DSA:3.40.50.300 11 247 6.1E-54 T 12-10-2018 TL08_24415 bc3f047cceb20b6858bf5e2267f185fd 549 ProSitePatterns PS00211 ABC transporters family signature. 411 425 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_24415 bc3f047cceb20b6858bf5e2267f185fd 549 Gene3D G3DSA:3.40.50.300 250 508 1.3E-35 T 12-10-2018 TL08_24415 bc3f047cceb20b6858bf5e2267f185fd 549 SUPERFAMILY SSF52540 15 236 3.22E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24415 bc3f047cceb20b6858bf5e2267f185fd 549 SMART SM00382 40 225 3.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 SUPERFAMILY SSF81271 416 488 2.13E-22 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 Gene3D G3DSA:3.30.70.260 686 766 2.3E-16 T 12-10-2018 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 SUPERFAMILY SSF81301 228 406 2.94E-60 T 12-10-2018 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 Pfam PF04607 Region found in RelA / SpoT proteins 271 380 4.0E-36 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 64 762 1.5E-263 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 SMART SM00954 271 381 2.1E-60 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 Gene3D G3DSA:1.10.3210.10 35 227 5.7E-78 T 12-10-2018 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 SUPERFAMILY SSF109604 40 226 6.8E-70 T 12-10-2018 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 Pfam PF13291 ACT domain 686 762 3.0E-16 T 12-10-2018 IPR002912 ACT domain TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 SUPERFAMILY SSF55021 686 765 4.16E-14 T 12-10-2018 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 Gene3D G3DSA:3.10.20.30 422 493 1.4E-31 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 Pfam PF02824 TGS domain 429 488 6.8E-23 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 Pfam PF13328 HD domain 64 211 8.2E-48 T 12-10-2018 IPR003607 HD/PDEase domain TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 SMART SM00471 79 189 1.2E-12 T 12-10-2018 IPR003607 HD/PDEase domain TL08_10530 a1d2ad1ae07f5b5663796215621b2c98 767 Gene3D G3DSA:3.30.460.10 229 361 8.2E-45 T 12-10-2018 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 Pfam PF00072 Response regulator receiver domain 33 136 3.7E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 SUPERFAMILY SSF52172 32 152 3.7E-25 T 12-10-2018 IPR011006 CheY-like superfamily TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 Gene3D G3DSA:3.40.50.12740 32 237 3.7E-50 T 12-10-2018 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 231 1.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 SMART SM00421 174 231 6.6E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 SMART SM00448 31 143 2.6E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 1.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 1.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 1.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 191 218 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20590 0caf06f635f5b197d6bf56eaa432603d 238 SUPERFAMILY SSF46894 171 237 2.45E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_20050 4cfaf03e74e07fb2cabd4983ba7066c6 261 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 5 236 4.5E-43 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 TL08_20050 4cfaf03e74e07fb2cabd4983ba7066c6 261 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 5 151 1.6E-41 T 12-10-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 TL08_20050 4cfaf03e74e07fb2cabd4983ba7066c6 261 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 5 45 6.3E-8 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal TL08_20050 4cfaf03e74e07fb2cabd4983ba7066c6 261 Gene3D G3DSA:3.30.70.2660 3 250 2.0E-48 T 12-10-2018 TL08_08225 c254f6fac2fa0b8a6d3416e685e5a47e 190 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 1 185 4.0E-53 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TL08_08225 c254f6fac2fa0b8a6d3416e685e5a47e 190 SUPERFAMILY SSF52374 1 185 2.13E-50 T 12-10-2018 TL08_08225 c254f6fac2fa0b8a6d3416e685e5a47e 190 Pfam PF01467 Cytidylyltransferase-like 2 160 1.8E-28 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TL08_08225 c254f6fac2fa0b8a6d3416e685e5a47e 190 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 186 26.806 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TL08_08225 c254f6fac2fa0b8a6d3416e685e5a47e 190 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 62 2.2E-9 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TL08_08225 c254f6fac2fa0b8a6d3416e685e5a47e 190 Gene3D G3DSA:3.40.50.620 1 189 4.9E-59 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_07675 423ceeb6725cd3ae5eb268b50437b476 272 Gene3D G3DSA:1.25.40.10 101 257 3.3E-36 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_07675 423ceeb6725cd3ae5eb268b50437b476 272 SMART SM00862 15 96 5.5E-11 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_07675 423ceeb6725cd3ae5eb268b50437b476 272 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 76 6.0E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_07675 423ceeb6725cd3ae5eb268b50437b476 272 SUPERFAMILY SSF48452 99 252 8.25E-29 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_07675 423ceeb6725cd3ae5eb268b50437b476 272 SMART SM01043 103 244 4.3E-34 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_07675 423ceeb6725cd3ae5eb268b50437b476 272 Gene3D G3DSA:1.10.10.10 1 98 2.9E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07675 423ceeb6725cd3ae5eb268b50437b476 272 SUPERFAMILY SSF46894 3 95 1.73E-13 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_07675 423ceeb6725cd3ae5eb268b50437b476 272 Pfam PF03704 Bacterial transcriptional activator domain 103 244 3.8E-29 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_20755 5c6b61ae55b66e2efd3c4d78e3c44542 178 Gene3D G3DSA:3.30.1310.10 23 123 3.7E-12 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_20755 5c6b61ae55b66e2efd3c4d78e3c44542 178 SUPERFAMILY SSF82607 25 113 5.75E-9 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_20755 5c6b61ae55b66e2efd3c4d78e3c44542 178 Pfam PF02575 YbaB/EbfC DNA-binding family 27 113 3.2E-13 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_09705 fad05f1fca869ae2b5fe12f920c925be 199 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TL08_09705 fad05f1fca869ae2b5fe12f920c925be 199 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 161 173 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TL08_09705 fad05f1fca869ae2b5fe12f920c925be 199 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 179 1.6E-58 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TL08_09705 fad05f1fca869ae2b5fe12f920c925be 199 SUPERFAMILY SSF54211 88 184 1.41E-28 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_09705 fad05f1fca869ae2b5fe12f920c925be 199 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 199 40.576 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TL08_09705 fad05f1fca869ae2b5fe12f920c925be 199 Gene3D G3DSA:3.30.230.40 1 90 4.5E-36 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TL08_09705 fad05f1fca869ae2b5fe12f920c925be 199 Gene3D G3DSA:3.30.230.40 91 199 7.0E-35 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TL08_09705 fad05f1fca869ae2b5fe12f920c925be 199 SUPERFAMILY SSF54211 3 86 3.54E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 291 5.7E-45 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 90 108 4.7E-14 T 12-10-2018 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 222 238 4.7E-14 T 12-10-2018 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 268 4.7E-14 T 12-10-2018 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 4.7E-14 T 12-10-2018 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 SUPERFAMILY SSF51905 2 179 6.91E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 Gene3D G3DSA:3.30.390.30 311 386 1.4E-12 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 Gene3D G3DSA:3.50.50.60 1 292 8.2E-95 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 93 102 6.8E-17 T 12-10-2018 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 223 237 6.8E-17 T 12-10-2018 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 268 6.8E-17 T 12-10-2018 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 159 6.8E-17 T 12-10-2018 TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 Gene3D G3DSA:3.50.50.60 103 229 8.2E-95 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 SUPERFAMILY SSF51905 132 299 3.78E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 Pfam PF14759 Reductase C-terminal 311 382 4.8E-12 T 12-10-2018 IPR028202 Reductase, C-terminal TL08_07660 8e49dcd240fe8a1629660bddf72d7643 387 SUPERFAMILY SSF55424 302 380 4.67E-19 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_06535 deea98c495a6c0c2d2fa52dd1c820b52 251 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 238 3.8E-104 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 TL08_06535 deea98c495a6c0c2d2fa52dd1c820b52 251 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 12-10-2018 IPR018336 Ribonuclease PH, conserved site TL08_06535 deea98c495a6c0c2d2fa52dd1c820b52 251 Pfam PF03725 3' exoribonuclease family, domain 2 160 226 3.4E-10 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_06535 deea98c495a6c0c2d2fa52dd1c820b52 251 SUPERFAMILY SSF54211 2 183 1.06E-40 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_06535 deea98c495a6c0c2d2fa52dd1c820b52 251 SUPERFAMILY SSF55666 156 242 8.25E-22 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_06535 deea98c495a6c0c2d2fa52dd1c820b52 251 Hamap MF_00564 Ribonuclease PH [rph]. 12 239 41.831 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 TL08_06535 deea98c495a6c0c2d2fa52dd1c820b52 251 Gene3D G3DSA:3.30.230.70 17 246 3.8E-57 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_06535 deea98c495a6c0c2d2fa52dd1c820b52 251 Pfam PF01138 3' exoribonuclease family, domain 1 12 141 2.1E-20 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 Gene3D G3DSA:3.40.50.2300 161 290 5.5E-77 T 12-10-2018 TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 SUPERFAMILY SSF47413 2 59 3.84E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 SMART SM00354 1 71 1.7E-31 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.8E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 59 314 1.1E-38 T 12-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 SUPERFAMILY SSF53822 61 330 1.14E-73 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 Gene3D G3DSA:3.40.50.2300 56 307 5.5E-77 T 12-10-2018 TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.4E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_26985 83c60d3182aa3593b26d634bece3ddf1 340 Gene3D G3DSA:1.10.260.40 1 55 3.2E-24 T 12-10-2018 TL08_05150 652ae13ca005b017b88237ccdda1a594 841 Pfam PF00271 Helicase conserved C-terminal domain 228 344 7.9E-12 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_05150 652ae13ca005b017b88237ccdda1a594 841 Pfam PF08482 ATP-dependent helicase C-terminal 698 829 6.0E-52 T 12-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal TL08_05150 652ae13ca005b017b88237ccdda1a594 841 SMART SM00487 25 206 1.5E-20 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_05150 652ae13ca005b017b88237ccdda1a594 841 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 27 841 6.9E-247 T 12-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 TL08_05150 652ae13ca005b017b88237ccdda1a594 841 Pfam PF04408 Helicase associated domain (HA2) 407 488 3.5E-9 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 TL08_05150 652ae13ca005b017b88237ccdda1a594 841 SMART SM00847 404 497 4.1E-7 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 TL08_05150 652ae13ca005b017b88237ccdda1a594 841 Gene3D G3DSA:3.40.50.300 19 199 8.9E-51 T 12-10-2018 TL08_05150 652ae13ca005b017b88237ccdda1a594 841 SUPERFAMILY SSF52540 38 354 1.09E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05150 652ae13ca005b017b88237ccdda1a594 841 SMART SM00490 246 344 5.8E-17 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_05150 652ae13ca005b017b88237ccdda1a594 841 Gene3D G3DSA:1.20.120.1080 391 483 7.1E-6 T 12-10-2018 TL08_05150 652ae13ca005b017b88237ccdda1a594 841 Gene3D G3DSA:3.40.50.300 200 361 6.2E-46 T 12-10-2018 TL08_05150 652ae13ca005b017b88237ccdda1a594 841 PIRSF PIRSF005496 22 841 3.0E-280 T 12-10-2018 TL08_00650 9f54ab4166a159949b1c736f47936e3a 295 Pfam PF00296 Luciferase-like monooxygenase 21 232 1.8E-42 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_00650 9f54ab4166a159949b1c736f47936e3a 295 SUPERFAMILY SSF51679 2 288 9.42E-50 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_00650 9f54ab4166a159949b1c736f47936e3a 295 Gene3D G3DSA:3.20.20.30 1 291 5.6E-54 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 SUPERFAMILY SSF51735 5 243 5.3E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 3.0E-62 T 12-10-2018 TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 8.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 8.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 8.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05200 db75f8b1e211fc69763350be4dd610cb 244 Gene3D G3DSA:3.40.50.720 1 244 1.6E-75 T 12-10-2018 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 11 471 1.7E-202 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 169 1.0E-48 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 PIRSF PIRSF000109 4 479 1.5E-197 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 SUPERFAMILY SSF48179 182 472 5.99E-118 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 184 470 7.5E-122 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 SMART SM01350 184 471 1.8E-202 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 Gene3D G3DSA:1.20.5.320 439 473 4.8E-19 T 12-10-2018 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 Gene3D G3DSA:1.10.1040.10 186 438 1.6E-100 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 259 271 - T 12-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 SUPERFAMILY SSF51735 9 182 5.45E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 9 32 5.9E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 360 382 5.9E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 255 282 5.9E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 72 101 5.9E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 125 150 5.9E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 173 201 5.9E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_17845 ade25fc2cf3429abdde941191ae43e72 479 Gene3D G3DSA:3.40.50.720 3 185 3.9E-54 T 12-10-2018 TL08_09795 21913d20e33b9086b4b56aeae58c39a4 185 SUPERFAMILY SSF52980 14 151 2.09E-17 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TL08_09795 21913d20e33b9086b4b56aeae58c39a4 185 Gene3D G3DSA:3.90.1570.10 11 170 5.3E-16 T 12-10-2018 TL08_09795 21913d20e33b9086b4b56aeae58c39a4 185 Pfam PF05685 Putative restriction endonuclease 24 184 9.8E-20 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TL08_17410 93c010087b74c05255e189bb33fded93 1398 Gene3D G3DSA:2.120.10.30 267 709 5.4E-66 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_17410 93c010087b74c05255e189bb33fded93 1398 Pfam PF06283 Trehalose utilisation 38 258 4.4E-58 T 12-10-2018 IPR029010 ThuA-like domain TL08_17410 93c010087b74c05255e189bb33fded93 1398 SUPERFAMILY SSF50952 272 691 3.01E-17 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TL08_17410 93c010087b74c05255e189bb33fded93 1398 Pfam PF00801 PKD domain 721 786 3.9E-10 T 12-10-2018 IPR000601 PKD domain TL08_17410 93c010087b74c05255e189bb33fded93 1398 SUPERFAMILY SSF52317 36 264 6.18E-35 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_17410 93c010087b74c05255e189bb33fded93 1398 Gene3D G3DSA:2.60.40.10 1049 1141 5.6E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_17410 93c010087b74c05255e189bb33fded93 1398 SMART SM00606 905 1035 3.2E-24 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 TL08_17410 93c010087b74c05255e189bb33fded93 1398 SUPERFAMILY SSF49785 909 1034 3.4E-22 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_17410 93c010087b74c05255e189bb33fded93 1398 SUPERFAMILY SSF49299 714 801 1.28E-17 T 12-10-2018 IPR035986 PKD domain superfamily TL08_17410 93c010087b74c05255e189bb33fded93 1398 Gene3D G3DSA:3.40.50.880 24 266 2.0E-71 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_17410 93c010087b74c05255e189bb33fded93 1398 Gene3D G3DSA:2.60.40.10 710 800 4.0E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_17410 93c010087b74c05255e189bb33fded93 1398 Pfam PF07995 Glucose / Sorbosone dehydrogenase 284 546 3.7E-34 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TL08_17410 93c010087b74c05255e189bb33fded93 1398 Gene3D G3DSA:2.60.120.260 908 1035 5.1E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_17410 93c010087b74c05255e189bb33fded93 1398 SMART SM00089 716 799 4.9E-17 T 12-10-2018 IPR022409 PKD/Chitinase domain TL08_17410 93c010087b74c05255e189bb33fded93 1398 Pfam PF03422 Carbohydrate binding module (family 6) 913 1034 5.9E-25 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 TL08_04880 533803b38b1830134d7e869d353dd186 699 Pfam PF13361 UvrD-like helicase C-terminal domain 281 402 2.6E-16 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TL08_04880 533803b38b1830134d7e869d353dd186 699 SUPERFAMILY SSF52540 7 567 1.82E-131 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04880 533803b38b1830134d7e869d353dd186 699 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 274 3.3E-46 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TL08_04880 533803b38b1830134d7e869d353dd186 699 Pfam PF13361 UvrD-like helicase C-terminal domain 436 545 3.7E-23 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TL08_04880 533803b38b1830134d7e869d353dd186 699 Gene3D G3DSA:3.40.50.300 437 569 4.2E-26 T 12-10-2018 TL08_04880 533803b38b1830134d7e869d353dd186 699 SMART SM00341 616 699 2.2E-11 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TL08_04880 533803b38b1830134d7e869d353dd186 699 Pfam PF00570 HRDC domain 620 685 1.3E-17 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TL08_04880 533803b38b1830134d7e869d353dd186 699 Gene3D G3DSA:1.10.150.80 618 690 3.2E-20 T 12-10-2018 TL08_04880 533803b38b1830134d7e869d353dd186 699 Gene3D G3DSA:1.10.10.160 109 192 6.5E-74 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily TL08_04880 533803b38b1830134d7e869d353dd186 699 Gene3D G3DSA:3.40.50.300 283 390 5.5E-23 T 12-10-2018 TL08_04880 533803b38b1830134d7e869d353dd186 699 SUPERFAMILY SSF47819 610 689 6.98E-20 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TL08_04880 533803b38b1830134d7e869d353dd186 699 Gene3D G3DSA:3.40.50.300 11 275 6.5E-74 T 12-10-2018 TL08_22515 34cfd2b0c1bc743642960cf680b4f10a 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 437 4.3E-141 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TL08_23050 85161fceeffd9026551a14b1a1bd3d96 410 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 20 406 1.2E-86 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 TL08_23050 85161fceeffd9026551a14b1a1bd3d96 410 SUPERFAMILY SSF55031 221 329 3.84E-23 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TL08_23050 85161fceeffd9026551a14b1a1bd3d96 410 PIRSF PIRSF001235 13 410 4.0E-117 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 TL08_23050 85161fceeffd9026551a14b1a1bd3d96 410 Gene3D G3DSA:3.40.630.10 29 403 1.6E-116 T 12-10-2018 TL08_23050 85161fceeffd9026551a14b1a1bd3d96 410 SUPERFAMILY SSF53187 19 410 2.46E-66 T 12-10-2018 TL08_23050 85161fceeffd9026551a14b1a1bd3d96 410 Gene3D G3DSA:3.30.70.360 219 332 1.6E-116 T 12-10-2018 TL08_23050 85161fceeffd9026551a14b1a1bd3d96 410 Pfam PF01546 Peptidase family M20/M25/M40 83 407 2.5E-26 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TL08_19120 c8b12ad532661f87a60766761a73d3b6 268 PIRSF PIRSF001365 1 266 3.6E-45 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_19120 c8b12ad532661f87a60766761a73d3b6 268 Pfam PF00701 Dihydrodipicolinate synthetase family 3 256 1.6E-33 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_19120 c8b12ad532661f87a60766761a73d3b6 268 SUPERFAMILY SSF51569 2 256 2.51E-47 T 12-10-2018 TL08_19120 c8b12ad532661f87a60766761a73d3b6 268 Gene3D G3DSA:3.20.20.70 1 268 4.3E-55 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_19120 c8b12ad532661f87a60766761a73d3b6 268 SMART SM01130 1 265 6.6E-40 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_15785 ce5df5e80e07707cbe0da339113e4720 246 Gene3D G3DSA:3.40.225.10 12 226 1.2E-43 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TL08_15785 ce5df5e80e07707cbe0da339113e4720 246 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 24 195 4.9E-32 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TL08_15785 ce5df5e80e07707cbe0da339113e4720 246 SUPERFAMILY SSF53639 21 206 2.55E-41 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TL08_15785 ce5df5e80e07707cbe0da339113e4720 246 SMART SM01007 18 195 1.8E-31 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TL08_06950 a746cd4caa6c69d25899a3d8b1399e27 290 SMART SM00382 27 211 7.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_06950 a746cd4caa6c69d25899a3d8b1399e27 290 Gene3D G3DSA:3.40.50.300 1 264 1.5E-58 T 12-10-2018 TL08_06950 a746cd4caa6c69d25899a3d8b1399e27 290 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_06950 a746cd4caa6c69d25899a3d8b1399e27 290 SUPERFAMILY SSF52540 16 219 1.71E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06950 a746cd4caa6c69d25899a3d8b1399e27 290 Pfam PF00005 ABC transporter 19 165 1.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 PIRSF PIRSF005719 1 1196 4.9E-251 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1190 22.085 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 Gene3D G3DSA:3.40.50.300 1035 1196 6.6E-43 T 12-10-2018 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 624 7.8E-17 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 SUPERFAMILY SSF75553 465 659 1.57E-25 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1188 4.8E-280 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1181 3.0E-71 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 Gene3D G3DSA:3.40.50.300 1 292 1.1E-55 T 12-10-2018 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 SMART SM00968 512 625 8.8E-19 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 Gene3D G3DSA:3.30.70.1620 572 652 9.1E-21 T 12-10-2018 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 Gene3D G3DSA:1.20.1060.20 500 656 9.1E-21 T 12-10-2018 TL08_22320 8fd7e153f26aa2a05587ccee98b344ce 1230 SUPERFAMILY SSF52540 2 1180 9.77E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07445 d36d1401050033a6cef721b585d88e31 314 Pfam PF03610 PTS system fructose IIA component 5 116 2.3E-25 T 12-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 TL08_07445 d36d1401050033a6cef721b585d88e31 314 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 228 307 5.2E-21 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_07445 d36d1401050033a6cef721b585d88e31 314 Gene3D G3DSA:3.40.50.510 1 129 6.4E-44 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 TL08_07445 d36d1401050033a6cef721b585d88e31 314 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 240 247 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TL08_07445 d36d1401050033a6cef721b585d88e31 314 Pfam PF00381 PTS HPr component phosphorylation site 232 308 8.6E-21 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_07445 d36d1401050033a6cef721b585d88e31 314 SUPERFAMILY SSF55594 228 313 1.44E-21 T 12-10-2018 IPR035895 HPr-like superfamily TL08_07445 d36d1401050033a6cef721b585d88e31 314 Gene3D G3DSA:3.30.1340.10 228 309 1.4E-22 T 12-10-2018 IPR035895 HPr-like superfamily TL08_07445 d36d1401050033a6cef721b585d88e31 314 PRINTS PR00107 Phosphocarrier protein signature 265 280 8.5E-9 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_07445 d36d1401050033a6cef721b585d88e31 314 PRINTS PR00107 Phosphocarrier protein signature 280 297 8.5E-9 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_07445 d36d1401050033a6cef721b585d88e31 314 PRINTS PR00107 Phosphocarrier protein signature 240 256 8.5E-9 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_07445 d36d1401050033a6cef721b585d88e31 314 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 4 120 6.9E-37 T 12-10-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain TL08_07445 d36d1401050033a6cef721b585d88e31 314 SUPERFAMILY SSF53062 4 122 7.59E-31 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 Pfam PF00672 HAMP domain 166 214 3.2E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 SMART SM00387 325 433 3.1E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 273 4.8E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 Gene3D G3DSA:3.30.565.10 301 431 9.6E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 SMART SM00304 166 218 6.3E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 SUPERFAMILY SSF47384 206 267 1.24E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 Gene3D G3DSA:1.10.287.130 164 270 1.3E-18 T 12-10-2018 TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 SUPERFAMILY SSF55874 288 429 8.7E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 SMART SM00388 219 277 1.1E-4 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_08700 13c2dadc0ad3e09ae38312ea58f26490 441 SUPERFAMILY SSF158472 167 216 4.97E-5 T 12-10-2018 TL08_15095 d3c1b98788179e62e3c08388f019aaf8 205 Pfam PF01944 Stage II sporulation protein M 29 193 3.9E-7 T 12-10-2018 IPR002798 Stage II sporulation protein M-like TL08_17810 7497277746abb9fe6936105a83780222 356 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TL08_17810 7497277746abb9fe6936105a83780222 356 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 344 2.1E-85 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TL08_17810 7497277746abb9fe6936105a83780222 356 Gene3D G3DSA:3.40.718.10 1 351 2.0E-121 T 12-10-2018 TL08_17810 7497277746abb9fe6936105a83780222 356 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 349 1.3E-156 T 12-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 TL08_17810 7497277746abb9fe6936105a83780222 356 SMART SM01329 4 346 9.5E-163 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TL08_17810 7497277746abb9fe6936105a83780222 356 SUPERFAMILY SSF53659 1 349 2.69E-111 T 12-10-2018 TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 6 543 2.9E-224 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 Pfam PF11941 Domain of unknown function (DUF3459) 491 592 1.1E-11 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 PIRSF PIRSF006337 2 580 3.0E-223 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 Pfam PF00128 Alpha amylase, catalytic domain 114 196 7.8E-12 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 Gene3D G3DSA:3.20.20.80 90 499 4.5E-164 T 12-10-2018 TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 SMART SM00642 102 498 7.6E-9 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 Gene3D G3DSA:1.10.10.760 431 471 4.5E-164 T 12-10-2018 TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 SUPERFAMILY SSF81296 7 80 2.62E-19 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 6 55 2.6E-6 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 SUPERFAMILY SSF51445 77 504 2.94E-104 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_17800 82a7f325cd42386c439dc3237bd8cebd 601 Gene3D G3DSA:2.60.40.10 4 86 9.0E-26 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_17530 f89a1df5aa9807a01728097ef2ae6ca6 252 Gene3D G3DSA:3.40.50.300 22 250 3.2E-61 T 12-10-2018 TL08_17530 f89a1df5aa9807a01728097ef2ae6ca6 252 Pfam PF00005 ABC transporter 44 194 2.4E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_17530 f89a1df5aa9807a01728097ef2ae6ca6 252 SMART SM00382 53 246 1.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17530 f89a1df5aa9807a01728097ef2ae6ca6 252 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_17530 f89a1df5aa9807a01728097ef2ae6ca6 252 SUPERFAMILY SSF52540 24 246 5.6E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_15195 9600d37dd965647e73c53cbe939f2986 266 SUPERFAMILY SSF46785 5 59 7.04E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_15195 9600d37dd965647e73c53cbe939f2986 266 Gene3D G3DSA:1.10.10.10 2 55 6.6E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_15195 9600d37dd965647e73c53cbe939f2986 266 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 3.0E-16 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_15195 9600d37dd965647e73c53cbe939f2986 266 SMART SM01134 74 236 1.5E-59 T 12-10-2018 TL08_15195 9600d37dd965647e73c53cbe939f2986 266 SUPERFAMILY SSF100950 75 236 1.08E-33 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_15195 9600d37dd965647e73c53cbe939f2986 266 SMART SM00420 6 58 3.3E-17 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_15195 9600d37dd965647e73c53cbe939f2986 266 Pfam PF00455 DeoR C terminal sensor domain 76 234 4.3E-47 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain TL08_15195 9600d37dd965647e73c53cbe939f2986 266 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TL08_15195 9600d37dd965647e73c53cbe939f2986 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.5E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_15195 9600d37dd965647e73c53cbe939f2986 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.5E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 Hamap MF_00015 LexA repressor [lexA]. 34 242 34.007 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 SUPERFAMILY SSF46785 34 100 9.93E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 Gene3D G3DSA:2.10.109.10 127 242 1.8E-41 T 12-10-2018 TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 Pfam PF00717 Peptidase S24-like 161 224 6.7E-15 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 TIGRFAM TIGR00498 lexA: repressor LexA 33 241 1.8E-77 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 Pfam PF01726 LexA DNA binding domain 33 96 7.5E-29 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 Gene3D G3DSA:1.10.10.10 34 99 1.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 SUPERFAMILY SSF51306 121 240 4.19E-35 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 169 180 7.5E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 197 209 7.5E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TL08_08580 78aeca5a59063ca910749d6d3d5976c8 242 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 158 168 7.5E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TL08_03005 d901552bec15744b79ad68d27e93f833 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03005 d901552bec15744b79ad68d27e93f833 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.002 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03005 d901552bec15744b79ad68d27e93f833 93 PIRSF PIRSF002144 1 93 3.0E-30 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03005 d901552bec15744b79ad68d27e93f833 93 Gene3D G3DSA:3.30.860.10 1 93 8.4E-39 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03005 d901552bec15744b79ad68d27e93f833 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 6.2E-47 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 TL08_03005 d901552bec15744b79ad68d27e93f833 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.0E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03005 d901552bec15744b79ad68d27e93f833 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.0E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03005 d901552bec15744b79ad68d27e93f833 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.0E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03005 d901552bec15744b79ad68d27e93f833 93 Pfam PF00203 Ribosomal protein S19 3 83 6.4E-36 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03005 d901552bec15744b79ad68d27e93f833 93 SUPERFAMILY SSF54570 3 84 4.58E-35 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_21445 bf4f9f6c1017d4dbda880db4cfb715a1 269 Pfam PF00005 ABC transporter 38 159 2.7E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_21445 bf4f9f6c1017d4dbda880db4cfb715a1 269 SMART SM00382 47 237 3.5E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_21445 bf4f9f6c1017d4dbda880db4cfb715a1 269 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_21445 bf4f9f6c1017d4dbda880db4cfb715a1 269 Gene3D G3DSA:3.40.50.300 17 266 2.2E-60 T 12-10-2018 TL08_21445 bf4f9f6c1017d4dbda880db4cfb715a1 269 SUPERFAMILY SSF52540 19 241 1.05E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05370 7181aa3d7a8e1ceaa4e766bff0ba7ea4 279 Gene3D G3DSA:1.10.260.40 23 96 4.8E-6 T 12-10-2018 TL08_05370 7181aa3d7a8e1ceaa4e766bff0ba7ea4 279 SUPERFAMILY SSF47413 29 81 6.68E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_05370 7181aa3d7a8e1ceaa4e766bff0ba7ea4 279 SMART SM00530 10 82 3.2E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_05370 7181aa3d7a8e1ceaa4e766bff0ba7ea4 279 Pfam PF13560 Helix-turn-helix domain 7 85 1.2E-13 T 12-10-2018 TL08_24315 987817e6eb829a52d576df107516dd34 179 Gene3D G3DSA:3.40.630.30 1 179 2.7E-33 T 12-10-2018 TL08_24315 987817e6eb829a52d576df107516dd34 179 SUPERFAMILY SSF55729 76 172 4.43E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_24315 987817e6eb829a52d576df107516dd34 179 Pfam PF13508 Acetyltransferase (GNAT) domain 88 156 6.4E-7 T 12-10-2018 IPR000182 GNAT domain TL08_21985 6b7d66f3174703dd611c3922ddfea525 529 SUPERFAMILY SSF53474 97 505 1.12E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21985 6b7d66f3174703dd611c3922ddfea525 529 Pfam PF00561 alpha/beta hydrolase fold 118 505 1.2E-45 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_25230 48b1af87cd514ee8eaacf1f1e2e191d2 169 Pfam PF10969 Protein of unknown function (DUF2771) 29 159 1.8E-20 T 12-10-2018 IPR024495 Protein of unknown function DUF2771 TL08_25230 48b1af87cd514ee8eaacf1f1e2e191d2 169 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 34 148 9.0E-8 T 12-10-2018 IPR024495 Protein of unknown function DUF2771 TL08_03070 1c673f321dc084ce1680396604a035eb 201 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 4 186 33.821 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TL08_03070 1c673f321dc084ce1680396604a035eb 201 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 34 186 1.0E-66 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TL08_03070 1c673f321dc084ce1680396604a035eb 201 Gene3D G3DSA:3.30.160.20 28 95 8.7E-29 T 12-10-2018 TL08_03070 1c673f321dc084ce1680396604a035eb 201 SUPERFAMILY SSF54211 102 181 4.3E-24 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_03070 1c673f321dc084ce1680396604a035eb 201 Pfam PF00333 Ribosomal protein S5, N-terminal domain 36 98 8.6E-28 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TL08_03070 1c673f321dc084ce1680396604a035eb 201 Gene3D G3DSA:3.30.230.10 100 189 2.8E-34 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_03070 1c673f321dc084ce1680396604a035eb 201 SUPERFAMILY SSF54768 34 99 2.3E-22 T 12-10-2018 TL08_03070 1c673f321dc084ce1680396604a035eb 201 ProSitePatterns PS00585 Ribosomal protein S5 signature. 51 83 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site TL08_03070 1c673f321dc084ce1680396604a035eb 201 Pfam PF03719 Ribosomal protein S5, C-terminal domain 110 180 3.1E-28 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TL08_06170 19aab4cf28ad5eba6a175c4813a7dd2f 242 SUPERFAMILY SSF53335 11 217 2.13E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_06170 19aab4cf28ad5eba6a175c4813a7dd2f 242 Pfam PF08241 Methyltransferase domain 51 143 2.3E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_06170 19aab4cf28ad5eba6a175c4813a7dd2f 242 Gene3D G3DSA:3.40.50.150 6 221 4.9E-47 T 12-10-2018 TL08_26450 e79cf1cce41eb128b8ef3b7d4b5bfd01 278 Gene3D G3DSA:3.90.45.10 24 191 5.4E-36 T 12-10-2018 IPR036821 Peptide deformylase superfamily TL08_26450 e79cf1cce41eb128b8ef3b7d4b5bfd01 278 Pfam PF04149 Domain of unknown function (DUF397) 232 273 2.0E-11 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_26450 e79cf1cce41eb128b8ef3b7d4b5bfd01 278 PRINTS PR01576 Peptide deformylase signature 137 155 7.9E-14 T 12-10-2018 IPR023635 Peptide deformylase TL08_26450 e79cf1cce41eb128b8ef3b7d4b5bfd01 278 PRINTS PR01576 Peptide deformylase signature 156 185 7.9E-14 T 12-10-2018 IPR023635 Peptide deformylase TL08_26450 e79cf1cce41eb128b8ef3b7d4b5bfd01 278 PRINTS PR01576 Peptide deformylase signature 70 99 7.9E-14 T 12-10-2018 IPR023635 Peptide deformylase TL08_26450 e79cf1cce41eb128b8ef3b7d4b5bfd01 278 PRINTS PR01576 Peptide deformylase signature 125 136 7.9E-14 T 12-10-2018 IPR023635 Peptide deformylase TL08_26450 e79cf1cce41eb128b8ef3b7d4b5bfd01 278 Hamap MF_00163 Peptide deformylase [def]. 30 198 19.226 T 12-10-2018 IPR023635 Peptide deformylase TL08_26450 e79cf1cce41eb128b8ef3b7d4b5bfd01 278 SUPERFAMILY SSF56420 26 185 1.83E-33 T 12-10-2018 IPR036821 Peptide deformylase superfamily TL08_26450 e79cf1cce41eb128b8ef3b7d4b5bfd01 278 Pfam PF01327 Polypeptide deformylase 33 185 5.6E-30 T 12-10-2018 IPR023635 Peptide deformylase TL08_22525 8fb14949ed155461dfa6c38168b2b19c 583 SMART SM01121 242 583 1.2E-66 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain TL08_22525 8fb14949ed155461dfa6c38168b2b19c 583 Pfam PF02734 DAK2 domain 35 200 2.0E-33 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TL08_22525 8fb14949ed155461dfa6c38168b2b19c 583 SMART SM01120 35 201 2.4E-50 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TL08_22525 8fb14949ed155461dfa6c38168b2b19c 583 Pfam PF13684 Dihydroxyacetone kinase family 243 583 4.0E-68 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain TL08_22525 8fb14949ed155461dfa6c38168b2b19c 583 Gene3D G3DSA:1.25.40.340 3 203 1.2E-12 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TL08_22525 8fb14949ed155461dfa6c38168b2b19c 583 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 583 1.7E-132 T 12-10-2018 IPR019986 DAK2 domain-containing protein YloV TL08_22525 8fb14949ed155461dfa6c38168b2b19c 583 SUPERFAMILY SSF101473 5 202 6.02E-34 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TL08_16305 d16973679a6f18953469f9ef4b58d419 382 Gene3D G3DSA:3.20.10.10 192 364 1.1E-120 T 12-10-2018 TL08_16305 d16973679a6f18953469f9ef4b58d419 382 PIRSF PIRSF006468 22 382 5.7E-112 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 TL08_16305 d16973679a6f18953469f9ef4b58d419 382 Pfam PF01063 Amino-transferase class IV 91 336 4.4E-29 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TL08_16305 d16973679a6f18953469f9ef4b58d419 382 ProSitePatterns PS00770 Aminotransferases class-IV signature. 254 287 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 TL08_16305 d16973679a6f18953469f9ef4b58d419 382 SUPERFAMILY SSF56752 31 378 4.45E-103 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TL08_16305 d16973679a6f18953469f9ef4b58d419 382 Gene3D G3DSA:3.30.470.10 46 377 1.1E-120 T 12-10-2018 TL08_16305 d16973679a6f18953469f9ef4b58d419 382 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 65 380 2.9E-106 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 TL08_25720 a284f1245145f16b0c112dca38f760cf 323 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 85 228 1.2E-43 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TL08_25720 a284f1245145f16b0c112dca38f760cf 323 Gene3D G3DSA:1.10.260.150 48 316 3.3E-69 T 12-10-2018 TL08_25720 a284f1245145f16b0c112dca38f760cf 323 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 85 228 8.8E-40 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 SUPERFAMILY SSF49299 827 908 5.36E-15 T 12-10-2018 IPR035986 PKD domain superfamily TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Gene3D G3DSA:2.120.10.30 48 441 3.5E-74 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Gene3D G3DSA:2.60.40.10 488 577 2.6E-20 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 SUPERFAMILY SSF49299 494 579 9.55E-16 T 12-10-2018 IPR035986 PKD domain superfamily TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 SUPERFAMILY SSF49785 691 817 5.44E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Gene3D G3DSA:2.60.40.10 823 906 1.1E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Pfam PF07995 Glucose / Sorbosone dehydrogenase 71 325 1.1E-33 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 SUPERFAMILY SSF50952 54 472 1.57E-30 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Gene3D G3DSA:2.60.120.260 687 817 1.0E-18 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Gene3D G3DSA:2.60.120.560 1038 1222 3.1E-32 T 12-10-2018 TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Pfam PF00801 PKD domain 502 569 3.1E-9 T 12-10-2018 IPR000601 PKD domain TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Pfam PF00801 PKD domain 838 893 8.9E-12 T 12-10-2018 IPR000601 PKD domain TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 SMART SM00089 826 908 2.4E-11 T 12-10-2018 IPR022409 PKD/Chitinase domain TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 SMART SM00089 496 576 1.0E-11 T 12-10-2018 IPR022409 PKD/Chitinase domain TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Pfam PF06439 Domain of Unknown Function (DUF1080) 1046 1221 2.3E-30 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 Pfam PF03422 Carbohydrate binding module (family 6) 696 817 2.3E-16 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 TL08_11925 bf8122e34d189ed767856fe71177eca4 1581 SMART SM00606 688 818 1.2E-12 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 SUPERFAMILY SSF50129 4 98 7.44E-35 T 12-10-2018 IPR011032 GroES-like superfamily TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 PRINTS PR00297 10kDa chaperonin signature 28 49 5.4E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 PRINTS PR00297 10kDa chaperonin signature 6 21 5.4E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 PRINTS PR00297 10kDa chaperonin signature 63 75 5.4E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 PRINTS PR00297 10kDa chaperonin signature 84 97 5.4E-31 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 Pfam PF00166 Chaperonin 10 Kd subunit 5 97 2.1E-35 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 Gene3D G3DSA:2.30.33.40 2 98 7.0E-39 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 ProSitePatterns PS00681 Chaperonins cpn10 signature. 6 30 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 Hamap MF_00580 10 kDa chaperonin [groS]. 5 98 26.182 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_24810 28e7ac8f62fe899ac01de89b4a4c7431 98 SMART SM00883 5 97 5.0E-55 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_15635 4ec18fe9b763fd4266073ae5b5b01136 241 SUPERFAMILY SSF52317 3 205 8.86E-37 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_15635 4ec18fe9b763fd4266073ae5b5b01136 241 Pfam PF03575 Peptidase family S51 3 201 2.6E-56 T 12-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 TL08_15635 4ec18fe9b763fd4266073ae5b5b01136 241 Gene3D G3DSA:3.40.50.880 1 219 2.0E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 SUPERFAMILY SSF51905 3 200 9.5E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 Pfam PF04324 BFD-like [2Fe-2S] binding domain 422 469 3.2E-12 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 Gene3D G3DSA:3.50.50.60 119 244 2.9E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 Gene3D G3DSA:3.50.50.60 6 301 2.9E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 Gene3D G3DSA:1.10.10.1100 422 474 6.5E-10 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 SUPERFAMILY SSF51905 156 310 1.32E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.1E-15 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 2.1E-15 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 2.1E-15 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.1E-15 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.1E-15 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 6.0E-9 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 6.0E-9 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 6.0E-9 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 6.0E-9 T 12-10-2018 TL08_09275 1bc9dd6fe676db2697d7cca920b3887f 485 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 301 7.1E-44 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 68 83 4.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 126 139 4.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 4.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 Pfam PF12697 Alpha/beta hydrolase family 45 302 1.4E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 SUPERFAMILY SSF53474 20 307 6.11E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 PRINTS PR00412 Epoxide hydrolase signature 49 67 1.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 PRINTS PR00412 Epoxide hydrolase signature 126 139 1.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 PRINTS PR00412 Epoxide hydrolase signature 284 306 1.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 PRINTS PR00412 Epoxide hydrolase signature 112 125 1.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_03430 f40d6e6429156473535b7dfd426c4ed8 308 Gene3D G3DSA:3.40.50.1820 21 308 1.9E-87 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15540 ed941e49341fcdbbb72b5d05114bf67b 126 Pfam PF12840 Helix-turn-helix domain 4 63 5.6E-12 T 12-10-2018 TL08_15540 ed941e49341fcdbbb72b5d05114bf67b 126 SMART SM00418 2 84 6.1E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_15540 ed941e49341fcdbbb72b5d05114bf67b 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 7.1E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_15540 ed941e49341fcdbbb72b5d05114bf67b 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 7.1E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_15540 ed941e49341fcdbbb72b5d05114bf67b 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 7.1E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_15540 ed941e49341fcdbbb72b5d05114bf67b 126 Gene3D G3DSA:1.10.10.10 1 107 7.0E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_15540 ed941e49341fcdbbb72b5d05114bf67b 126 SUPERFAMILY SSF46785 3 113 5.08E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 162 176 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 14 492 2.1E-140 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 Pfam PF02637 GatB domain 349 493 3.1E-39 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 Gene3D G3DSA:1.10.10.410 436 495 1.7E-15 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 Pfam PF02934 GatB/GatE catalytic domain 17 311 1.5E-104 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 13 497 35.058 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 Gene3D G3DSA:1.10.150.380 319 434 9.7E-16 T 12-10-2018 TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 SUPERFAMILY SSF55931 16 317 9.16E-111 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 SMART SM00845 349 496 4.4E-54 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TL08_22805 92f303904ef3594347be2f8c0545ea0a 500 SUPERFAMILY SSF89095 349 493 1.05E-25 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TL08_18595 b42b71abd46841e6c70c8df4d1d2883b 182 Gene3D G3DSA:1.10.357.10 1 181 7.7E-28 T 12-10-2018 TL08_18595 b42b71abd46841e6c70c8df4d1d2883b 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 4.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18595 b42b71abd46841e6c70c8df4d1d2883b 182 SUPERFAMILY SSF46689 1 71 5.99E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_08365 9315fb0bbf32e2daeb48c93eb97cbf19 480 Pfam PF02653 Branched-chain amino acid transport system / permease component 164 464 1.1E-30 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_07290 7f59f275e770f500f142ac5e967f3c2b 427 PIRSF PIRSF000412 8 425 3.8E-157 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TL08_07290 7f59f275e770f500f142ac5e967f3c2b 427 Pfam PF00464 Serine hydroxymethyltransferase 13 389 2.4E-153 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TL08_07290 7f59f275e770f500f142ac5e967f3c2b 427 Gene3D G3DSA:3.40.640.10 42 292 9.0E-167 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_07290 7f59f275e770f500f142ac5e967f3c2b 427 SUPERFAMILY SSF53383 12 424 3.67E-160 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_07290 7f59f275e770f500f142ac5e967f3c2b 427 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 12 424 49.19 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TL08_07290 7f59f275e770f500f142ac5e967f3c2b 427 Gene3D G3DSA:3.90.1150.10 17 395 9.0E-167 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_02530 0cf2bc06545567d1a846deec56a0b7db 574 Gene3D G3DSA:3.40.50.970 363 565 1.1E-64 T 12-10-2018 TL08_02530 0cf2bc06545567d1a846deec56a0b7db 574 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 566 31.515 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 TL08_02530 0cf2bc06545567d1a846deec56a0b7db 574 SUPERFAMILY SSF52518 367 558 2.95E-18 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_02530 0cf2bc06545567d1a846deec56a0b7db 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 176 2.6E-27 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TL08_02530 0cf2bc06545567d1a846deec56a0b7db 574 PIRSF PIRSF004983 1 572 1.3E-129 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 TL08_02530 0cf2bc06545567d1a846deec56a0b7db 574 SUPERFAMILY SSF52518 8 181 4.71E-29 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_02530 0cf2bc06545567d1a846deec56a0b7db 574 Gene3D G3DSA:3.40.50.970 2 203 5.3E-66 T 12-10-2018 TL08_02530 0cf2bc06545567d1a846deec56a0b7db 574 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 427 2.0E-102 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 TL08_02530 0cf2bc06545567d1a846deec56a0b7db 574 Gene3D G3DSA:3.40.50.1220 213 360 2.9E-16 T 12-10-2018 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 85 99 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 SMART SM00996 13 486 0.0 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 PIRSF PIRSF001109 1 487 1.0E-188 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 9 479 47.614 T 12-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 Gene3D G3DSA:3.40.50.1480 16 487 1.1E-235 T 12-10-2018 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 13 486 4.1E-143 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 Gene3D G3DSA:3.40.50.720 248 408 1.1E-235 T 12-10-2018 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 14 479 5.7E-190 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 SMART SM00997 245 407 4.2E-105 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 245 407 5.5E-80 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 SUPERFAMILY SSF52283 12 487 4.7E-109 T 12-10-2018 TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 SUPERFAMILY SSF51735 245 407 1.7E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_23310 f5c05124fd2aeaa3cda04560cceb3f32 487 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 267 283 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TL08_26435 58aae4cb1aed69ef915132dad5b726f0 684 Gene3D G3DSA:2.40.10.10 221 295 1.9E-35 T 12-10-2018 TL08_26435 58aae4cb1aed69ef915132dad5b726f0 684 Gene3D G3DSA:2.40.10.10 296 393 1.9E-35 T 12-10-2018 TL08_26435 58aae4cb1aed69ef915132dad5b726f0 684 Gene3D G3DSA:2.60.40.10 429 505 9.9E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_26435 58aae4cb1aed69ef915132dad5b726f0 684 Gene3D G3DSA:2.60.40.10 518 599 1.0E-10 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_26435 58aae4cb1aed69ef915132dad5b726f0 684 Gene3D G3DSA:3.30.300.50 46 127 1.3E-7 T 12-10-2018 IPR035070 Streptogrisin prodomain TL08_26435 58aae4cb1aed69ef915132dad5b726f0 684 SUPERFAMILY SSF50494 221 390 7.15E-23 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_26435 58aae4cb1aed69ef915132dad5b726f0 684 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 362 373 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site TL08_12365 36ddb69665087ae99f9c3a9f346c5084 570 ProSitePatterns PS00211 ABC transporters family signature. 467 481 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12365 36ddb69665087ae99f9c3a9f346c5084 570 SUPERFAMILY SSF90123 7 318 7.59E-45 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_12365 36ddb69665087ae99f9c3a9f346c5084 570 Pfam PF00005 ABC transporter 366 494 3.5E-8 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12365 36ddb69665087ae99f9c3a9f346c5084 570 Gene3D G3DSA:1.20.1560.10 5 318 5.5E-44 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_12365 36ddb69665087ae99f9c3a9f346c5084 570 SUPERFAMILY SSF52540 338 566 1.58E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12365 36ddb69665087ae99f9c3a9f346c5084 570 Pfam PF00664 ABC transporter transmembrane region 26 283 7.3E-15 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_12365 36ddb69665087ae99f9c3a9f346c5084 570 Gene3D G3DSA:3.40.50.300 332 569 9.0E-43 T 12-10-2018 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 Pfam PF13424 Tetratricopeptide repeat 828 896 8.2E-11 T 12-10-2018 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 Gene3D G3DSA:1.10.10.10 8 110 5.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 Gene3D G3DSA:3.40.50.300 284 448 2.4E-20 T 12-10-2018 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 SUPERFAMILY SSF52540 292 563 1.23E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 PRINTS PR00364 Disease resistance protein signature 325 340 1.6E-6 T 12-10-2018 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 PRINTS PR00364 Disease resistance protein signature 408 422 1.6E-6 T 12-10-2018 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 PRINTS PR00364 Disease resistance protein signature 494 508 1.6E-6 T 12-10-2018 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 Gene3D G3DSA:1.25.40.10 112 281 5.8E-40 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 SUPERFAMILY SSF48452 108 270 1.02E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 Pfam PF00486 Transcriptional regulatory protein, C terminal 34 106 4.3E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 Pfam PF03704 Bacterial transcriptional activator domain 114 254 3.8E-34 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 SUPERFAMILY SSF46894 14 106 4.25E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 SMART SM00862 27 106 1.8E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 SMART SM00028 868 901 49.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 SMART SM00028 908 941 33.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 SMART SM00028 828 861 56.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 SUPERFAMILY SSF48452 756 941 5.48E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 Gene3D G3DSA:1.25.40.10 699 948 4.0E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_02015 fc43abd28a79762ed0593fbd94f370f9 990 SMART SM01043 113 254 1.4E-38 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_16085 d023e76b3d8080d483106aa4f9fe6f83 988 SMART SM00758 29 169 3.6E-28 T 12-10-2018 IPR011658 PA14 domain TL08_16085 d023e76b3d8080d483106aa4f9fe6f83 988 Pfam PF06439 Domain of Unknown Function (DUF1080) 797 986 6.3E-36 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 TL08_16085 d023e76b3d8080d483106aa4f9fe6f83 988 Gene3D G3DSA:2.60.120.380 63 162 5.3E-10 T 12-10-2018 TL08_16085 d023e76b3d8080d483106aa4f9fe6f83 988 Pfam PF16990 Carbohydrate binding module (family 35) 663 793 1.1E-6 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 TL08_16085 d023e76b3d8080d483106aa4f9fe6f83 988 Gene3D G3DSA:2.60.120.560 768 988 3.9E-71 T 12-10-2018 TL08_16085 d023e76b3d8080d483106aa4f9fe6f83 988 SUPERFAMILY SSF49785 662 791 1.87E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_16085 d023e76b3d8080d483106aa4f9fe6f83 988 SUPERFAMILY SSF56988 77 194 1.16E-7 T 12-10-2018 TL08_16085 d023e76b3d8080d483106aa4f9fe6f83 988 SUPERFAMILY SSF50952 197 511 1.7E-12 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TL08_16085 d023e76b3d8080d483106aa4f9fe6f83 988 Pfam PF07691 PA14 domain 30 166 4.1E-15 T 12-10-2018 IPR011658 PA14 domain TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 Gene3D G3DSA:3.75.10.10 15 405 4.2E-141 T 12-10-2018 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 Gene3D G3DSA:1.10.3930.10 77 158 4.2E-141 T 12-10-2018 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 Pfam PF02274 Amidinotransferase 27 404 3.1E-98 T 12-10-2018 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 PRINTS PR01466 Bacterial arginine deiminase signature 187 202 1.5E-48 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 PRINTS PR01466 Bacterial arginine deiminase signature 159 177 1.5E-48 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 PRINTS PR01466 Bacterial arginine deiminase signature 11 31 1.5E-48 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 PRINTS PR01466 Bacterial arginine deiminase signature 344 361 1.5E-48 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 PRINTS PR01466 Bacterial arginine deiminase signature 364 378 1.5E-48 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 PRINTS PR01466 Bacterial arginine deiminase signature 387 405 1.5E-48 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 TIGRFAM TIGR01078 arcA: arginine deiminase 15 408 1.0E-148 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 SUPERFAMILY SSF55909 11 408 5.1E-116 T 12-10-2018 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 Hamap MF_00242 Arginine deiminase [arcA]. 10 408 41.89 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TL08_00505 75264ee92f3251e04f32e156b54e89ba 409 PIRSF PIRSF006356 2 408 1.8E-138 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 TL08_03850 da070a93cf6680e557c37d32dfdadfc6 500 Gene3D G3DSA:2.60.40.10 326 445 1.4E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_11725 15e42e253f0bc73e713c64e46bb80541 191 SUPERFAMILY SSF54534 70 186 2.55E-23 T 12-10-2018 TL08_11725 15e42e253f0bc73e713c64e46bb80541 191 Gene3D G3DSA:3.10.50.40 69 187 2.0E-21 T 12-10-2018 TL08_11725 15e42e253f0bc73e713c64e46bb80541 191 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 96 184 5.1E-16 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TL08_06665 53ee87fbda485abab91b8c819e7a07f1 218 Gene3D G3DSA:1.10.357.10 80 217 1.4E-27 T 12-10-2018 TL08_06665 53ee87fbda485abab91b8c819e7a07f1 218 Gene3D G3DSA:1.10.10.60 12 68 2.9E-19 T 12-10-2018 TL08_06665 53ee87fbda485abab91b8c819e7a07f1 218 SUPERFAMILY SSF46689 14 90 4.84E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06665 53ee87fbda485abab91b8c819e7a07f1 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06665 53ee87fbda485abab91b8c819e7a07f1 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06665 53ee87fbda485abab91b8c819e7a07f1 218 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 160 213 1.9E-11 T 12-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type TL08_06665 53ee87fbda485abab91b8c819e7a07f1 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 5.7E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_22300 b900b4adeafe57dc6d0f234e7d7496e1 108 SUPERFAMILY SSF55729 11 98 7.98E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_22300 b900b4adeafe57dc6d0f234e7d7496e1 108 Pfam PF14542 GCN5-related N-acetyl-transferase 20 96 1.2E-19 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase TL08_22300 b900b4adeafe57dc6d0f234e7d7496e1 108 Gene3D G3DSA:3.40.630.30 11 102 2.6E-22 T 12-10-2018 TL08_21990 221229c770c460705653f84cf2010883 578 Pfam PF00795 Carbon-nitrogen hydrolase 9 254 4.6E-29 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TL08_21990 221229c770c460705653f84cf2010883 578 SUPERFAMILY SSF56317 4 254 2.75E-61 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TL08_21990 221229c770c460705653f84cf2010883 578 Gene3D G3DSA:3.40.50.620 297 575 1.9E-105 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_21990 221229c770c460705653f84cf2010883 578 SUPERFAMILY SSF52402 285 555 2.12E-71 T 12-10-2018 TL08_21990 221229c770c460705653f84cf2010883 578 TIGRFAM TIGR00552 nadE: NAD+ synthetase 303 550 4.2E-54 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TL08_21990 221229c770c460705653f84cf2010883 578 Gene3D G3DSA:3.60.110.10 4 289 6.4E-99 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TL08_21990 221229c770c460705653f84cf2010883 578 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 7 573 28.623 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TL08_21990 221229c770c460705653f84cf2010883 578 PIRSF PIRSF006630 4 575 4.7E-199 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TL08_21990 221229c770c460705653f84cf2010883 578 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 39 54 - T 12-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 TL08_21990 221229c770c460705653f84cf2010883 578 Pfam PF02540 NAD synthase 300 547 1.1E-67 T 12-10-2018 IPR022310 NAD/GMP synthase TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF14765 Polyketide synthase dehydratase 2364 2636 5.3E-46 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.30.70.3290 1969 2347 5.2E-114 T 12-10-2018 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:1.10.1200.10 3084 3176 5.9E-29 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF55048 683 745 7.19E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF08990 Erythronolide synthase docking 2 27 1.1E-8 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.40.50.720 915 1413 4.2E-141 T 12-10-2018 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.40.50.1820 3197 3470 3.4E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1470 1485 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00825 Beta-ketoacyl synthase 1536 1957 6.9E-210 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00825 Beta-ketoacyl synthase 36 459 8.6E-208 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2824 3004 1.0E-47 T 12-10-2018 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1161 1341 1.9E-46 T 12-10-2018 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF53474 3131 3469 2.63E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF51735 2821 3060 2.99E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.10.129.110 2355 2641 9.8E-80 T 12-10-2018 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00826 2364 2525 8.8E-55 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.40.50.720 2642 3074 3.6E-112 T 12-10-2018 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1787 1904 4.8E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 406 7.8E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF52151 559 843 1.36E-65 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF00550 Phosphopantetheine attachment site 3104 3168 1.8E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF00550 Phosphopantetheine attachment site 1445 1511 6.6E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.40.366.10 561 859 1.1E-152 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.40.366.10 2036 2304 5.2E-114 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF51735 1159 1372 9.12E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF00698 Acyl transferase domain 562 875 1.1E-82 T 12-10-2018 IPR014043 Acyl transferase TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF00698 Acyl transferase domain 2073 2292 3.2E-37 T 12-10-2018 IPR014043 Acyl transferase TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF51735 960 1148 5.91E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00824 Thioesterase 3254 3469 1.3E-79 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:1.10.1200.10 1423 1516 5.7E-30 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00823 Phosphopantetheine attachment site 3101 3173 2.5E-28 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00823 Phosphopantetheine attachment site 1443 1515 4.8E-26 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3128 3143 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF47336 3096 3187 4.32E-19 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.40.47.10 25 480 8.3E-182 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.40.47.10 1520 1957 3.8E-180 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Gene3D G3DSA:3.30.70.3290 481 902 1.1E-152 T 12-10-2018 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 283 2.8E-84 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1534 1779 1.6E-83 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF47336 1438 1549 1.44E-23 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 409 527 1.7E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1907 2018 1.4E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF53901 31 405 1.12E-95 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF55048 2145 2202 4.58E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF00975 Thioesterase domain 3279 3468 2.4E-19 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM01294 3101 3169 7.8E-7 T 12-10-2018 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM01294 1444 1511 2.0E-5 T 12-10-2018 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF52151 2037 2295 5.23E-56 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF08659 KR domain 2825 3002 6.9E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 Pfam PF08659 KR domain 1161 1340 3.8E-52 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 563 856 8.5E-111 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2038 2304 8.7E-83 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF53901 1530 1902 4.53E-97 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1692 1708 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_14575 6ea79a628aa537c255ae7baa3e7974d6 3472 SUPERFAMILY SSF51735 2643 2806 1.34E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24440 f9e0ce0096cbd0de89f9684507dce923 267 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 33 143 4.3E-34 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24440 f9e0ce0096cbd0de89f9684507dce923 267 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 36 259 1.2E-78 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24440 f9e0ce0096cbd0de89f9684507dce923 267 Pfam PF13183 4Fe-4S dicluster domain 177 249 3.5E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TL08_24440 f9e0ce0096cbd0de89f9684507dce923 267 Gene3D G3DSA:3.10.20.30 24 137 9.7E-32 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TL08_24440 f9e0ce0096cbd0de89f9684507dce923 267 SUPERFAMILY SSF54292 30 137 3.77E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TL08_24440 f9e0ce0096cbd0de89f9684507dce923 267 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 179 190 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TL08_24440 f9e0ce0096cbd0de89f9684507dce923 267 SUPERFAMILY SSF46548 138 264 5.23E-33 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TL08_24440 f9e0ce0096cbd0de89f9684507dce923 267 Gene3D G3DSA:1.10.1060.10 138 266 1.3E-47 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TL08_13115 f4f4f99c9d4dba11f804799d63ca2ed3 187 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 129 2.5E-15 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 TL08_13115 f4f4f99c9d4dba11f804799d63ca2ed3 187 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 185 2.5E-24 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type TL08_13115 f4f4f99c9d4dba11f804799d63ca2ed3 187 Gene3D G3DSA:1.20.120.450 1 133 4.8E-15 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_13115 f4f4f99c9d4dba11f804799d63ca2ed3 187 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 8 185 5.3E-45 T 12-10-2018 IPR017520 Conserved hypothetical protein CHP03086 TL08_13115 f4f4f99c9d4dba11f804799d63ca2ed3 187 SUPERFAMILY SSF109854 4 134 9.89E-26 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_24500 795579712f4dbf7b4239fa5205f5ae9c 290 Pfam PF00459 Inositol monophosphatase family 69 285 1.4E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_24500 795579712f4dbf7b4239fa5205f5ae9c 290 Gene3D G3DSA:3.30.540.10 30 166 9.1E-18 T 12-10-2018 TL08_24500 795579712f4dbf7b4239fa5205f5ae9c 290 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 112 124 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TL08_24500 795579712f4dbf7b4239fa5205f5ae9c 290 SUPERFAMILY SSF56655 34 285 5.37E-36 T 12-10-2018 TL08_24500 795579712f4dbf7b4239fa5205f5ae9c 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 196 217 1.9E-6 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_24500 795579712f4dbf7b4239fa5205f5ae9c 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 230 254 1.9E-6 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_24500 795579712f4dbf7b4239fa5205f5ae9c 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 111 127 1.9E-6 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_24500 795579712f4dbf7b4239fa5205f5ae9c 290 Gene3D G3DSA:3.40.190.80 171 283 1.8E-19 T 12-10-2018 TL08_03390 372fb4a7bffd52c99b8a53c7614cf564 232 SMART SM00862 145 217 3.1E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_03390 372fb4a7bffd52c99b8a53c7614cf564 232 Gene3D G3DSA:1.10.10.10 126 229 9.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03390 372fb4a7bffd52c99b8a53c7614cf564 232 SUPERFAMILY SSF52172 1 166 1.1E-34 T 12-10-2018 IPR011006 CheY-like superfamily TL08_03390 372fb4a7bffd52c99b8a53c7614cf564 232 Pfam PF00072 Response regulator receiver domain 3 112 6.3E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_03390 372fb4a7bffd52c99b8a53c7614cf564 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 217 9.2E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_03390 372fb4a7bffd52c99b8a53c7614cf564 232 Gene3D G3DSA:3.40.50.2300 1 121 9.7E-32 T 12-10-2018 TL08_03390 372fb4a7bffd52c99b8a53c7614cf564 232 SMART SM00448 1 112 1.5E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_16180 4166f762609f0e2909b634bc3b3d9902 198 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 63 195 4.0E-18 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 TL08_02580 4be6a4633f2040149c3619b44c295203 415 SUPERFAMILY SSF54292 277 400 1.27E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TL08_02580 4be6a4633f2040149c3619b44c295203 415 Pfam PF00175 Oxidoreductase NAD-binding domain 160 268 4.6E-16 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TL08_02580 4be6a4633f2040149c3619b44c295203 415 PRINTS PR00406 Cytochrome B5 reductase signature 136 150 8.2E-5 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 TL08_02580 4be6a4633f2040149c3619b44c295203 415 PRINTS PR00406 Cytochrome B5 reductase signature 195 206 8.2E-5 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 TL08_02580 4be6a4633f2040149c3619b44c295203 415 PRINTS PR00406 Cytochrome B5 reductase signature 159 178 8.2E-5 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 TL08_02580 4be6a4633f2040149c3619b44c295203 415 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 319 391 5.8E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TL08_02580 4be6a4633f2040149c3619b44c295203 415 SUPERFAMILY SSF63380 32 148 3.4E-17 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TL08_02580 4be6a4633f2040149c3619b44c295203 415 Gene3D G3DSA:2.40.30.10 28 146 3.2E-18 T 12-10-2018 TL08_02580 4be6a4633f2040149c3619b44c295203 415 Gene3D G3DSA:3.40.50.80 153 289 2.7E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TL08_02580 4be6a4633f2040149c3619b44c295203 415 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 349 357 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TL08_02580 4be6a4633f2040149c3619b44c295203 415 SUPERFAMILY SSF52343 139 284 6.55E-33 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TL08_02580 4be6a4633f2040149c3619b44c295203 415 Gene3D G3DSA:3.10.20.30 298 404 8.7E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 Gene3D G3DSA:3.40.50.720 7 261 1.3E-74 T 12-10-2018 TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 SUPERFAMILY SSF51735 18 260 9.13E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 30 258 1.3E-58 T 12-10-2018 TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 25 42 1.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 3.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 3.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_11175 1b5a0e6d66d2603a94926a0ef5e5fc2d 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26880 1569547d95fd66b822b64a44b47e2be8 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 3.1E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_26880 1569547d95fd66b822b64a44b47e2be8 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 3.1E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_26880 1569547d95fd66b822b64a44b47e2be8 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 3.1E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_26880 1569547d95fd66b822b64a44b47e2be8 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 3.1E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_26880 1569547d95fd66b822b64a44b47e2be8 259 Pfam PF00557 Metallopeptidase family M24 11 245 1.4E-43 T 12-10-2018 IPR000994 Peptidase M24 TL08_26880 1569547d95fd66b822b64a44b47e2be8 259 Hamap MF_01974 Methionine aminopeptidase [map]. 2 254 32.466 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_26880 1569547d95fd66b822b64a44b47e2be8 259 Gene3D G3DSA:3.90.230.10 1 258 6.8E-79 T 12-10-2018 TL08_26880 1569547d95fd66b822b64a44b47e2be8 259 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 2.0E-72 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_26880 1569547d95fd66b822b64a44b47e2be8 259 SUPERFAMILY SSF55920 1 253 9.94E-72 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TL08_03790 945d21733a77697b13cbd23d205a725b 332 SUPERFAMILY SSF53067 3 129 1.25E-34 T 12-10-2018 TL08_03790 945d21733a77697b13cbd23d205a725b 332 Gene3D G3DSA:3.30.420.40 1 127 3.1E-46 T 12-10-2018 TL08_03790 945d21733a77697b13cbd23d205a725b 332 Gene3D G3DSA:3.30.420.150 129 321 2.1E-61 T 12-10-2018 TL08_03790 945d21733a77697b13cbd23d205a725b 332 SUPERFAMILY SSF53067 133 317 3.56E-38 T 12-10-2018 TL08_03790 945d21733a77697b13cbd23d205a725b 332 Pfam PF02541 Ppx/GppA phosphatase family 25 314 2.4E-72 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 TL08_05390 0ae6b2bcf50302e0e89a3860b07bd78a 304 Gene3D G3DSA:1.10.10.10 5 92 5.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05390 0ae6b2bcf50302e0e89a3860b07bd78a 304 Pfam PF03466 LysR substrate binding domain 90 297 1.5E-26 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_05390 0ae6b2bcf50302e0e89a3860b07bd78a 304 SUPERFAMILY SSF53850 92 300 1.71E-26 T 12-10-2018 TL08_05390 0ae6b2bcf50302e0e89a3860b07bd78a 304 SUPERFAMILY SSF46785 9 114 5.83E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05390 0ae6b2bcf50302e0e89a3860b07bd78a 304 Gene3D G3DSA:3.40.190.10 173 266 1.7E-29 T 12-10-2018 TL08_05390 0ae6b2bcf50302e0e89a3860b07bd78a 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 64 2.7E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_05390 0ae6b2bcf50302e0e89a3860b07bd78a 304 Gene3D G3DSA:3.40.190.10 94 172 1.7E-29 T 12-10-2018 TL08_19000 9d804309c52919a20fccf8ed331c67d4 267 PIRSF PIRSF006648 1 266 3.5E-73 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_19000 9d804309c52919a20fccf8ed331c67d4 267 Pfam PF01061 ABC-2 type transporter 12 218 7.6E-29 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 PIRSF PIRSF000521 181 412 2.4E-31 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 PIRSF PIRSF000521 110 162 0.027 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 PIRSF PIRSF000521 2 127 1.9E-5 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 Pfam PF00202 Aminotransferase class-III 19 409 4.4E-74 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 2 410 5.0E-195 T 12-10-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 Gene3D G3DSA:3.90.1150.10 9 404 4.1E-105 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 412 1.9E-140 T 12-10-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 268 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 SUPERFAMILY SSF53383 9 409 3.17E-104 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_01995 a5334c7f73ac5c0544983c8e86b571ab 418 Gene3D G3DSA:3.40.640.10 54 314 4.1E-105 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 TIGRFAM TIGR00484 EF-G: translation elongation factor G 7 696 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 SUPERFAMILY SSF54980 608 694 1.29E-30 T 12-10-2018 IPR035647 EF-G domain III/V-like TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Gene3D G3DSA:3.30.230.10 486 692 4.7E-89 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Hamap MF_00054_B Elongation factor G [fusA]. 8 696 109.853 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Gene3D G3DSA:3.30.70.240 609 679 4.7E-89 T 12-10-2018 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Pfam PF03764 Elongation factor G, domain IV 481 603 4.0E-47 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Gene3D G3DSA:3.30.70.870 408 485 1.1E-31 T 12-10-2018 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 SUPERFAMILY SSF54980 406 483 9.71E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 4.1E-35 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Gene3D G3DSA:3.40.50.300 5 297 1.5E-112 T 12-10-2018 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 SUPERFAMILY SSF50447 267 406 3.53E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 SMART SM00889 482 603 6.6E-72 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 SMART SM00838 605 692 2.2E-58 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Gene3D G3DSA:2.40.30.10 298 407 5.6E-40 T 12-10-2018 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 SUPERFAMILY SSF52540 8 284 1.31E-108 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Pfam PF14492 Elongation Factor G, domain II 406 480 8.4E-34 T 12-10-2018 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Pfam PF03144 Elongation factor Tu domain 2 326 393 9.7E-14 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 PRINTS PR00315 GTP-binding elongation factor signature 80 90 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 PRINTS PR00315 GTP-binding elongation factor signature 60 68 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 PRINTS PR00315 GTP-binding elongation factor signature 96 107 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 PRINTS PR00315 GTP-binding elongation factor signature 132 141 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 SUPERFAMILY SSF54211 481 604 2.78E-40 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Pfam PF00679 Elongation factor G C-terminus 606 691 6.4E-31 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TL08_02965 3b34c54bf23d9545111618906f9ee0ad 699 Pfam PF00009 Elongation factor Tu GTP binding domain 11 284 2.5E-67 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_08065 0fd298cfda415a970c1c56210fa57483 204 Pfam PF06821 Serine hydrolase 6 181 3.6E-24 T 12-10-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 TL08_08065 0fd298cfda415a970c1c56210fa57483 204 Gene3D G3DSA:3.40.50.1820 1 189 5.0E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_08065 0fd298cfda415a970c1c56210fa57483 204 SUPERFAMILY SSF53474 5 185 1.08E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13325 16d2a3c9a7b619535829b05a6da3613f 292 SUPERFAMILY SSF53213 38 289 7.46E-68 T 12-10-2018 TL08_13325 16d2a3c9a7b619535829b05a6da3613f 292 PIRSF PIRSF006157 34 292 9.5E-71 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 TL08_13325 16d2a3c9a7b619535829b05a6da3613f 292 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 57 269 2.4E-32 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TL08_13325 16d2a3c9a7b619535829b05a6da3613f 292 Gene3D G3DSA:3.40.830.10 13 292 6.5E-66 T 12-10-2018 TL08_03080 96f3b7f92db3e3dd77525c2363293be9 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 144 8.4E-42 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03080 96f3b7f92db3e3dd77525c2363293be9 147 Gene3D G3DSA:3.100.10.10 67 147 2.9E-21 T 12-10-2018 TL08_03080 96f3b7f92db3e3dd77525c2363293be9 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 147 18.738 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TL08_03080 96f3b7f92db3e3dd77525c2363293be9 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 145 1.3E-30 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P TL08_03080 96f3b7f92db3e3dd77525c2363293be9 147 SUPERFAMILY SSF52080 8 146 6.02E-39 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TL08_03080 96f3b7f92db3e3dd77525c2363293be9 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 141 - T 12-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 Gene3D G3DSA:1.10.730.10 17 793 6.2E-189 T 12-10-2018 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 Gene3D G3DSA:3.40.50.620 28 582 6.2E-189 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 PRINTS PR00986 Valyl-tRNA synthetase signature 386 399 4.3E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 PRINTS PR00986 Valyl-tRNA synthetase signature 43 54 4.3E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 PRINTS PR00986 Valyl-tRNA synthetase signature 257 274 4.3E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 PRINTS PR00986 Valyl-tRNA synthetase signature 502 523 4.3E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 PRINTS PR00986 Valyl-tRNA synthetase signature 533 551 4.3E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 Hamap MF_02005 Valine--tRNA ligase [valS]. 8 837 27.506 T 12-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 SUPERFAMILY SSF50677 220 370 2.88E-32 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 SUPERFAMILY SSF52374 7 624 3.67E-101 T 12-10-2018 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 Pfam PF08264 Anticodon-binding domain of tRNA 658 806 4.0E-24 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 Gene3D G3DSA:3.90.740.10 203 382 6.2E-189 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 50 61 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 SUPERFAMILY SSF47323 633 843 3.36E-30 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 118 619 3.2E-68 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_17520 1b275120455cb99ba891af06e6c9b88d 855 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 104 1.7E-18 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_15420 345697178eeca40c86b5350303ac1bc5 187 SUPERFAMILY SSF46785 4 173 2.8E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_15420 345697178eeca40c86b5350303ac1bc5 187 Pfam PF03551 Transcriptional regulator PadR-like family 8 80 2.3E-8 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal TL08_15420 345697178eeca40c86b5350303ac1bc5 187 Gene3D G3DSA:1.10.10.10 1 100 2.6E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22890 94f8fcaae7e0bd28974aa3b470d587e9 242 SUPERFAMILY SSF46785 24 95 3.2E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_22890 94f8fcaae7e0bd28974aa3b470d587e9 242 SUPERFAMILY SSF55781 97 237 1.05E-21 T 12-10-2018 TL08_22890 94f8fcaae7e0bd28974aa3b470d587e9 242 Pfam PF01614 Bacterial transcriptional regulator 174 216 5.2E-5 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_22890 94f8fcaae7e0bd28974aa3b470d587e9 242 SMART SM00346 23 110 8.4E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_22890 94f8fcaae7e0bd28974aa3b470d587e9 242 Gene3D G3DSA:1.10.10.10 22 95 3.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22890 94f8fcaae7e0bd28974aa3b470d587e9 242 Gene3D G3DSA:3.30.450.40 96 172 3.9E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_22890 94f8fcaae7e0bd28974aa3b470d587e9 242 Pfam PF09339 IclR helix-turn-helix domain 26 74 2.2E-6 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_22890 94f8fcaae7e0bd28974aa3b470d587e9 242 Gene3D G3DSA:3.30.450.40 173 240 8.8E-11 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_10675 9fcb80150d76b97cfc49bec90ca45c50 323 SUPERFAMILY SSF52540 5 226 1.98E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10675 9fcb80150d76b97cfc49bec90ca45c50 323 Pfam PF00005 ABC transporter 23 165 9.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_10675 9fcb80150d76b97cfc49bec90ca45c50 323 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_10675 9fcb80150d76b97cfc49bec90ca45c50 323 Gene3D G3DSA:3.40.50.300 2 230 6.2E-65 T 12-10-2018 TL08_10675 9fcb80150d76b97cfc49bec90ca45c50 323 SMART SM00382 31 214 2.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_10675 9fcb80150d76b97cfc49bec90ca45c50 323 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 307 2.8E-103 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TL08_11635 72a9a4c82595a0f0aa9e22b59c019214 262 Gene3D G3DSA:3.20.20.70 2 262 1.2E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_11635 72a9a4c82595a0f0aa9e22b59c019214 262 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 255 59.75 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11635 72a9a4c82595a0f0aa9e22b59c019214 262 Pfam PF00121 Triosephosphate isomerase 7 253 5.6E-89 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11635 72a9a4c82595a0f0aa9e22b59c019214 262 SUPERFAMILY SSF51351 4 255 3.4E-90 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11635 72a9a4c82595a0f0aa9e22b59c019214 262 ProSitePatterns PS00171 Triosephosphate isomerase active site. 171 181 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11635 72a9a4c82595a0f0aa9e22b59c019214 262 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 7 247 6.8E-59 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_08845 d7544d97ca789f5ef2acf42a444f4865 506 Pfam PF01078 Magnesium chelatase, subunit ChlI 193 395 1.5E-79 T 12-10-2018 IPR000523 Magnesium chelatase ChlI domain TL08_08845 d7544d97ca789f5ef2acf42a444f4865 506 Gene3D G3DSA:3.30.230.10 1 169 2.7E-8 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_08845 d7544d97ca789f5ef2acf42a444f4865 506 Gene3D G3DSA:3.40.50.300 194 505 1.7E-42 T 12-10-2018 TL08_08845 d7544d97ca789f5ef2acf42a444f4865 506 SUPERFAMILY SSF54211 2 170 8.72E-30 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_08845 d7544d97ca789f5ef2acf42a444f4865 506 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 501 2.9E-134 T 12-10-2018 IPR004482 Mg chelatase-related protein TL08_08845 d7544d97ca789f5ef2acf42a444f4865 506 SUPERFAMILY SSF52540 193 500 2.08E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08845 d7544d97ca789f5ef2acf42a444f4865 506 SMART SM00382 213 395 3.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08845 d7544d97ca789f5ef2acf42a444f4865 506 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 2.1E-33 T 12-10-2018 TL08_08845 d7544d97ca789f5ef2acf42a444f4865 506 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 406 501 1.9E-23 T 12-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 Gene3D G3DSA:3.40.50.720 1 168 1.0E-41 T 12-10-2018 TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 103 1.2E-18 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 Gene3D G3DSA:1.10.3730.10 169 272 2.1E-38 T 12-10-2018 TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 SUPERFAMILY SSF48179 165 272 2.55E-34 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 270 26.496 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 270 1.3E-76 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 166 270 5.3E-37 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 PIRSF PIRSF000193 1 273 5.1E-67 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 SUPERFAMILY SSF51735 3 162 7.82E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_02320 fc5994141ebce394fa76acdf17d498d0 284 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 226 248 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Gene3D G3DSA:3.40.50.720 1268 1366 1.6E-37 T 12-10-2018 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Gene3D G3DSA:2.20.25.520 952 1014 2.4E-24 T 12-10-2018 IPR038576 Methyltransferase putative zinc binding domain superfamily TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 SUPERFAMILY SSF53335 1041 1216 2.56E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Gene3D G3DSA:3.40.50.150 1015 1216 1.4E-48 T 12-10-2018 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Pfam PF13489 Methyltransferase domain 1061 1199 1.5E-17 T 12-10-2018 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 SUPERFAMILY SSF52540 4 240 9.1E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Gene3D G3DSA:1.25.40.10 535 821 1.6E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 ProSitePatterns PS00622 LuxR-type HTH domain signature. 873 900 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Pfam PF00196 Bacterial regulatory proteins, luxR family 858 909 1.1E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Pfam PF08421 Putative zinc binding domain 965 1024 2.6E-19 T 12-10-2018 IPR013630 Methyltransferase putative zinc binding domain TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 SMART SM00382 24 200 0.0077 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 889 901 1.0E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 873 889 1.0E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 873 1.0E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 SUPERFAMILY SSF46894 854 910 5.44E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 SMART SM00421 856 913 1.0E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Gene3D G3DSA:3.40.50.300 4 176 5.8E-5 T 12-10-2018 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Pfam PF08484 C-methyltransferase C-terminal domain 1205 1361 3.8E-55 T 12-10-2018 IPR013691 C-methyltransferase TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Gene3D G3DSA:1.10.10.10 837 914 2.9E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 SUPERFAMILY SSF48452 606 739 3.79E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05820 ae6e2fcecb91d141c2be09642965c49b 1366 Pfam PF13191 AAA ATPase domain 7 168 5.1E-17 T 12-10-2018 TL08_26310 50645a3681d430c80e4c3af6d516d140 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 144 164 2.6E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_26310 50645a3681d430c80e4c3af6d516d140 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 110 2.6E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_26310 50645a3681d430c80e4c3af6d516d140 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 130 2.6E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_26310 50645a3681d430c80e4c3af6d516d140 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 94 2.6E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_26310 50645a3681d430c80e4c3af6d516d140 168 SMART SM00347 54 154 2.6E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_26310 50645a3681d430c80e4c3af6d516d140 168 SUPERFAMILY SSF46785 34 166 2.25E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_26310 50645a3681d430c80e4c3af6d516d140 168 Gene3D G3DSA:1.10.10.10 24 166 1.0E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26310 50645a3681d430c80e4c3af6d516d140 168 ProSitePatterns PS01117 MarR-type HTH domain signature. 93 127 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TL08_26310 50645a3681d430c80e4c3af6d516d140 168 Pfam PF12802 MarR family 61 118 7.0E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_05020 52dedf9e78a732a378263d75677c72a3 781 SMART SM00825 Beta-ketoacyl synthase 17 433 1.4E-143 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_05020 52dedf9e78a732a378263d75677c72a3 781 Gene3D G3DSA:3.40.366.10 704 715 7.9E-9 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_05020 52dedf9e78a732a378263d75677c72a3 781 Gene3D G3DSA:3.30.70.3290 716 758 7.9E-9 T 12-10-2018 TL08_05020 52dedf9e78a732a378263d75677c72a3 781 SUPERFAMILY SSF52151 541 641 8.63E-10 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_05020 52dedf9e78a732a378263d75677c72a3 781 Gene3D G3DSA:3.40.47.10 14 433 1.7E-138 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05020 52dedf9e78a732a378263d75677c72a3 781 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 544 758 5.9E-5 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_05020 52dedf9e78a732a378263d75677c72a3 781 Gene3D G3DSA:3.30.70.3290 446 524 2.8E-37 T 12-10-2018 TL08_05020 52dedf9e78a732a378263d75677c72a3 781 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 383 495 8.0E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_05020 52dedf9e78a732a378263d75677c72a3 781 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 168 184 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_05020 52dedf9e78a732a378263d75677c72a3 781 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 17 254 7.5E-55 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_05020 52dedf9e78a732a378263d75677c72a3 781 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 380 3.9E-37 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_05020 52dedf9e78a732a378263d75677c72a3 781 Gene3D G3DSA:3.40.366.10 525 635 2.8E-37 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_05020 52dedf9e78a732a378263d75677c72a3 781 SUPERFAMILY SSF53901 14 377 1.71E-69 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_21625 3ec08cd9ef7fa2ef17edea3a5345ace6 458 Gene3D G3DSA:3.20.20.70 207 458 7.4E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_21625 3ec08cd9ef7fa2ef17edea3a5345ace6 458 Pfam PF01474 Class-II DAHP synthetase family 31 453 3.5E-186 T 12-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TL08_21625 3ec08cd9ef7fa2ef17edea3a5345ace6 458 SUPERFAMILY SSF51569 11 457 3.44E-188 T 12-10-2018 TL08_21625 3ec08cd9ef7fa2ef17edea3a5345ace6 458 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 27 457 2.5E-211 T 12-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TL08_11125 75699ece4c441007e7178913204c4865 510 Pfam PF00232 Glycosyl hydrolase family 1 417 495 9.3E-26 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_11125 75699ece4c441007e7178913204c4865 510 Pfam PF00232 Glycosyl hydrolase family 1 16 385 2.1E-114 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_11125 75699ece4c441007e7178913204c4865 510 Gene3D G3DSA:3.20.20.80 11 499 2.4E-161 T 12-10-2018 TL08_11125 75699ece4c441007e7178913204c4865 510 SUPERFAMILY SSF51445 16 495 2.86E-147 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_11125 75699ece4c441007e7178913204c4865 510 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 21 35 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TL08_11125 75699ece4c441007e7178913204c4865 510 PRINTS PR00131 Glycosyl hydrolase family 1 signature 373 381 9.4E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_11125 75699ece4c441007e7178913204c4865 510 PRINTS PR00131 Glycosyl hydrolase family 1 signature 299 313 9.4E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_11125 75699ece4c441007e7178913204c4865 510 PRINTS PR00131 Glycosyl hydrolase family 1 signature 466 478 9.4E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_11125 75699ece4c441007e7178913204c4865 510 PRINTS PR00131 Glycosyl hydrolase family 1 signature 421 432 9.4E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_11125 75699ece4c441007e7178913204c4865 510 PRINTS PR00131 Glycosyl hydrolase family 1 signature 442 459 9.4E-22 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 26 513 86.377 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 SUPERFAMILY SSF55347 205 512 1.57E-110 T 12-10-2018 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 217 512 8.5E-110 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 Gene3D G3DSA:3.30.360.10 204 513 1.6E-118 T 12-10-2018 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 SUPERFAMILY SSF51735 16 218 2.76E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 PIRSF PIRSF000110 9 514 4.9E-174 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 247 264 4.4E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 354 380 4.4E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 195 223 4.4E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 265 281 4.4E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 171 184 4.4E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 26 513 6.9E-197 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 205 211 - T 12-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 Gene3D G3DSA:3.40.50.720 26 203 5.6E-52 T 12-10-2018 TL08_11685 0abfe806c50836a39554d05c4d2b0647 514 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 30 215 2.1E-60 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TL08_01910 bff889ee444ca16df0dbefca121fbe0a 283 Pfam PF00950 ABC 3 transport family 18 269 1.6E-42 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TL08_01910 bff889ee444ca16df0dbefca121fbe0a 283 SUPERFAMILY SSF81345 10 268 2.62E-32 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 SMART SM00388 209 274 7.8E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 430 2.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 384 2.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 2.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 411 2.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 SMART SM00304 155 208 8.6E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 430 3.3E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 SMART SM00387 316 433 1.4E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 SUPERFAMILY SSF55874 265 431 2.46E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 SUPERFAMILY SSF158472 156 205 8.89E-8 T 12-10-2018 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 Gene3D G3DSA:1.10.287.130 159 270 2.3E-24 T 12-10-2018 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 Pfam PF00672 HAMP domain 156 204 2.1E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 Pfam PF00512 His Kinase A (phospho-acceptor) domain 210 273 4.0E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 Gene3D G3DSA:3.30.565.10 271 431 1.4E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_02710 34f74d61e1c49f4d8c8eb08e0737d17a 439 SUPERFAMILY SSF47384 193 273 3.14E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_01300 3148cf44584987eb998b861686b965bc 189 Gene3D G3DSA:3.40.30.10 52 188 5.0E-20 T 12-10-2018 TL08_01300 3148cf44584987eb998b861686b965bc 189 Pfam PF08534 Redoxin 61 170 6.9E-8 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 TL08_01300 3148cf44584987eb998b861686b965bc 189 SUPERFAMILY SSF52833 58 184 1.24E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_01300 3148cf44584987eb998b861686b965bc 189 ProSitePatterns PS00194 Thioredoxin family active site. 79 97 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 SUPERFAMILY SSF100920 358 514 8.63E-59 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 Gene3D G3DSA:2.60.34.10 351 478 1.6E-58 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 Gene3D G3DSA:1.20.1270.10 481 581 3.2E-31 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 PRINTS PR00301 70kDa heat shock protein signature 31 43 7.5E-75 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 PRINTS PR00301 70kDa heat shock protein signature 307 323 7.5E-75 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 PRINTS PR00301 70kDa heat shock protein signature 443 459 7.5E-75 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 PRINTS PR00301 70kDa heat shock protein signature 114 134 7.5E-75 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 PRINTS PR00301 70kDa heat shock protein signature 174 184 7.5E-75 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 PRINTS PR00301 70kDa heat shock protein signature 362 381 7.5E-75 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 PRINTS PR00301 70kDa heat shock protein signature 54 62 7.5E-75 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 PRINTS PR00301 70kDa heat shock protein signature 3 16 7.5E-75 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 PRINTS PR00301 70kDa heat shock protein signature 339 359 7.5E-75 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 Gene3D G3DSA:3.30.420.40 162 339 1.3E-146 T 12-10-2018 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 618 35.879 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 Gene3D G3DSA:3.90.640.10 200 288 1.3E-146 T 12-10-2018 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 Pfam PF00012 Hsp70 protein 4 577 1.1E-238 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 577 4.2E-273 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 SUPERFAMILY SSF53067 1 159 3.02E-58 T 12-10-2018 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 Gene3D G3DSA:3.30.420.40 5 350 1.3E-146 T 12-10-2018 TL08_26430 741c2bf4a0eba80d21e4eafe6fc6079b 622 SUPERFAMILY SSF53067 162 356 2.41E-62 T 12-10-2018 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 282 51.232 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 309 1012 1.3E-152 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 308 1014 20.292 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 Gene3D G3DSA:3.30.930.10 1 205 7.6E-100 T 12-10-2018 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 281 2.5E-127 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 Gene3D G3DSA:1.20.58.180 206 286 6.0E-28 T 12-10-2018 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 1.2E-56 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 1.2E-56 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 1.2E-56 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 1.2E-56 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 242 258 1.2E-56 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 1.2E-56 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 287 1.7E-122 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 311 882 3.5E-169 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 SUPERFAMILY SSF55681 3 281 2.73E-110 T 12-10-2018 TL08_15575 c60e4fdd43217eb0f3036a5071fe88b4 1021 SUPERFAMILY SSF109604 714 818 3.45E-6 T 12-10-2018 TL08_20620 c50f9ca7bb51f203f7d6232c76a0e16a 406 SUPERFAMILY SSF53901 12 273 5.52E-56 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_20620 c50f9ca7bb51f203f7d6232c76a0e16a 406 Gene3D G3DSA:3.40.47.10 142 391 4.4E-119 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_20620 c50f9ca7bb51f203f7d6232c76a0e16a 406 Gene3D G3DSA:3.40.47.10 13 279 4.4E-119 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_20620 c50f9ca7bb51f203f7d6232c76a0e16a 406 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TL08_20620 c50f9ca7bb51f203f7d6232c76a0e16a 406 Pfam PF00108 Thiolase, N-terminal domain 13 266 3.6E-54 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TL08_20620 c50f9ca7bb51f203f7d6232c76a0e16a 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 16 397 8.0E-124 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_20620 c50f9ca7bb51f203f7d6232c76a0e16a 406 PIRSF PIRSF000429 8 400 5.2E-120 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_20620 c50f9ca7bb51f203f7d6232c76a0e16a 406 Pfam PF02803 Thiolase, C-terminal domain 276 397 1.4E-36 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TL08_20620 c50f9ca7bb51f203f7d6232c76a0e16a 406 SUPERFAMILY SSF53901 277 397 1.28E-38 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_24080 08f27b4fadc9e3e031464a8265b2c2e0 373 SUPERFAMILY SSF53901 8 237 4.76E-25 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_24080 08f27b4fadc9e3e031464a8265b2c2e0 373 SUPERFAMILY SSF53901 224 371 3.64E-13 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_24080 08f27b4fadc9e3e031464a8265b2c2e0 373 Gene3D G3DSA:3.40.47.10 256 346 6.3E-9 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_24080 08f27b4fadc9e3e031464a8265b2c2e0 373 Gene3D G3DSA:3.40.47.10 2 240 9.3E-26 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_24080 08f27b4fadc9e3e031464a8265b2c2e0 373 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 73 211 4.9E-13 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_24080 08f27b4fadc9e3e031464a8265b2c2e0 373 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 268 340 4.6E-5 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_02705 a14f0ea932a41b889fb0a0b13c319d44 303 Gene3D G3DSA:3.75.10.10 37 300 8.6E-53 T 12-10-2018 TL08_02705 a14f0ea932a41b889fb0a0b13c319d44 303 Pfam PF02274 Amidinotransferase 92 301 2.6E-10 T 12-10-2018 TL08_02705 a14f0ea932a41b889fb0a0b13c319d44 303 SUPERFAMILY SSF55909 32 302 2.75E-50 T 12-10-2018 TL08_06075 75f437750e0b369c1de64847f6b3c134 130 Gene3D G3DSA:1.10.1660.10 1 126 2.5E-29 T 12-10-2018 TL08_06075 75f437750e0b369c1de64847f6b3c134 130 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_06075 75f437750e0b369c1de64847f6b3c134 130 SMART SM00422 1 70 2.6E-34 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_06075 75f437750e0b369c1de64847f6b3c134 130 Pfam PF13411 MerR HTH family regulatory protein 1 69 7.9E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_06075 75f437750e0b369c1de64847f6b3c134 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.0E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_06075 75f437750e0b369c1de64847f6b3c134 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.0E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_06075 75f437750e0b369c1de64847f6b3c134 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.0E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_06075 75f437750e0b369c1de64847f6b3c134 130 SUPERFAMILY SSF46955 1 114 9.89E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_16745 edc62401556a4c8facb438828d4b7c02 293 SUPERFAMILY SSF53697 10 290 6.41E-41 T 12-10-2018 TL08_16745 edc62401556a4c8facb438828d4b7c02 293 Gene3D G3DSA:3.40.50.10490 8 155 9.1E-24 T 12-10-2018 TL08_16745 edc62401556a4c8facb438828d4b7c02 293 Gene3D G3DSA:3.40.50.10490 156 281 2.8E-18 T 12-10-2018 TL08_16745 edc62401556a4c8facb438828d4b7c02 293 Pfam PF01380 SIS domain 36 133 1.1E-5 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TL08_11520 086080f56dc3ed2a5b42e8bb2b0b1d2f 96 SMART SM01409 28 92 1.9E-13 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TL08_11520 086080f56dc3ed2a5b42e8bb2b0b1d2f 96 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 21 91 8.5E-26 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_11520 086080f56dc3ed2a5b42e8bb2b0b1d2f 96 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 21 93 13.975 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_11520 086080f56dc3ed2a5b42e8bb2b0b1d2f 96 SUPERFAMILY SSF63562 21 92 2.62E-22 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TL08_11520 086080f56dc3ed2a5b42e8bb2b0b1d2f 96 Pfam PF01192 RNA polymerase Rpb6 28 90 2.2E-14 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TL08_11520 086080f56dc3ed2a5b42e8bb2b0b1d2f 96 Gene3D G3DSA:3.90.940.10 21 96 7.3E-19 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TL08_14030 095fe862ca7c40183194fe14da7ab0fc 295 Pfam PF13560 Helix-turn-helix domain 21 100 2.6E-17 T 12-10-2018 TL08_14030 095fe862ca7c40183194fe14da7ab0fc 295 SUPERFAMILY SSF47413 45 96 3.1E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_14030 095fe862ca7c40183194fe14da7ab0fc 295 Gene3D G3DSA:1.10.260.40 44 117 1.2E-7 T 12-10-2018 TL08_14030 095fe862ca7c40183194fe14da7ab0fc 295 SMART SM00530 25 97 2.3E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 SUPERFAMILY SSF50447 207 304 4.57E-30 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 Gene3D G3DSA:2.40.30.10 208 337 2.5E-52 T 12-10-2018 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 Gene3D G3DSA:2.40.30.10 341 395 2.2E-24 T 12-10-2018 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 395 5.6E-217 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 Gene3D G3DSA:3.40.50.300 1 205 1.6E-68 T 12-10-2018 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 SUPERFAMILY SSF50465 305 397 4.6E-34 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.8E-57 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 Pfam PF03143 Elongation factor Tu C-terminal domain 303 395 8.2E-31 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 Pfam PF03144 Elongation factor Tu domain 2 227 297 1.7E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 58.075 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 SUPERFAMILY SSF52540 6 221 1.92E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TL08_02975 a1052998f997e4c3b488785851f6ac0b 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 5.2E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TL08_15495 ac89976c4318d228c80364edef4f0d4a 432 Gene3D G3DSA:3.40.190.10 68 393 2.5E-120 T 12-10-2018 TL08_15495 ac89976c4318d228c80364edef4f0d4a 432 Pfam PF13416 Bacterial extracellular solute-binding protein 55 367 7.5E-27 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_15495 ac89976c4318d228c80364edef4f0d4a 432 Gene3D G3DSA:3.40.190.10 152 418 2.5E-120 T 12-10-2018 TL08_15495 ac89976c4318d228c80364edef4f0d4a 432 SUPERFAMILY SSF53850 25 430 1.41E-58 T 12-10-2018 TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 Pfam PF00501 AMP-binding enzyme 511 910 2.1E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 SUPERFAMILY SSF52777 42 237 7.23E-32 T 12-10-2018 TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 Pfam PF13193 AMP-binding enzyme C-terminal domain 918 993 9.0E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 Pfam PF00668 Condensation domain 40 403 3.5E-40 T 12-10-2018 IPR001242 Condensation domain TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 Gene3D G3DSA:3.30.300.30 905 1009 1.8E-30 T 12-10-2018 TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 SUPERFAMILY SSF56801 494 1033 3.01E-149 T 12-10-2018 TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 Gene3D G3DSA:3.30.559.10 42 245 1.1E-50 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 SMART SM00823 Phosphopantetheine attachment site 1021 1090 4.4E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 Gene3D G3DSA:3.40.50.12780 498 904 3.9E-129 T 12-10-2018 TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 Gene3D G3DSA:3.40.50.1820 1010 1120 6.2E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 532 934 4.0E-124 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 SUPERFAMILY SSF47336 1014 1084 2.22E-17 T 12-10-2018 IPR036736 ACP-like superfamily TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 Pfam PF00550 Phosphopantetheine attachment site 1022 1085 3.7E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 ProSitePatterns PS00455 Putative AMP-binding domain signature. 662 673 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 SUPERFAMILY SSF52777 230 474 1.89E-26 T 12-10-2018 TL08_06730 a0956b6d2cb417f183c8fe3a64a1296f 1129 Gene3D G3DSA:3.30.559.30 267 485 1.1E-37 T 12-10-2018 TL08_17850 a0d4eadafca84b73af06ebe52b643f04 351 Pfam PF04018 Domain of unknown function (DUF368) 9 284 1.0E-60 T 12-10-2018 IPR007163 Protein of unknown function DUF368 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2673 3071 2.6E-123 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1136 1544 3.8E-119 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 73 471 2.1E-121 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2793 2804 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.30.559.30 2374 2629 3.9E-131 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1260 1271 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF52777 1902 2158 4.45E-38 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF00550 Phosphopantetheine attachment site 3165 3227 1.5E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF00550 Phosphopantetheine attachment site 1629 1690 1.4E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF00550 Phosphopantetheine attachment site 559 620 2.2E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2034 2181 1.6E-38 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF52777 641 844 2.78E-46 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.40.50.12780 1103 1514 1.0E-124 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.30.300.30 3041 3151 1.4E-35 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF47336 1620 1691 1.28E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.30.300.30 1515 1613 2.0E-30 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.30.559.10 646 1017 1.9E-141 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF00501 AMP-binding enzyme 50 447 5.3E-87 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF00501 AMP-binding enzyme 1116 1520 2.3E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF00501 AMP-binding enzyme 2652 3047 4.4E-89 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF52777 830 1075 3.0E-57 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.30.559.30 1886 2159 2.2E-76 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.30.559.10 1695 1885 9.6E-55 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.30.559.30 828 1073 1.9E-141 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF52777 2188 2388 4.74E-41 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF47336 550 621 9.21E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF52777 1702 1890 1.33E-36 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:1.10.1200.10 547 629 1.4E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:1.10.1200.10 1614 1694 3.6E-25 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.40.50.12780 39 439 1.2E-131 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.40.50.12780 2643 3039 5.3E-128 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF56801 21 570 5.89E-146 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF47336 3154 3228 6.28E-20 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.30.300.30 440 546 1.2E-34 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:1.10.1200.10 3152 3231 7.5E-27 T 12-10-2018 IPR036736 ACP-like superfamily TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF56801 2611 3170 1.83E-147 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3186 3201 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF00668 Condensation domain 2189 2631 8.4E-95 T 12-10-2018 IPR001242 Condensation domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF00668 Condensation domain 645 1087 1.1E-94 T 12-10-2018 IPR001242 Condensation domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF00668 Condensation domain 1705 2162 4.4E-72 T 12-10-2018 IPR001242 Condensation domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF56801 1066 1640 8.77E-139 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SMART SM00823 Phosphopantetheine attachment site 1627 1695 9.9E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SMART SM00823 Phosphopantetheine attachment site 557 627 3.6E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SMART SM00823 Phosphopantetheine attachment site 3162 3231 5.5E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 SUPERFAMILY SSF52777 2374 2616 3.22E-56 T 12-10-2018 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Gene3D G3DSA:3.30.559.10 2195 2564 3.9E-131 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF13193 AMP-binding enzyme C-terminal domain 1528 1602 4.1E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF13193 AMP-binding enzyme C-terminal domain 3055 3135 3.1E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_16350 758b19727627ac0a99802d8344ebf754 3241 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 530 5.2E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_26445 3c8f302a1ff32a7303d1b5afb22216a7 165 Pfam PF00293 NUDIX domain 11 134 6.2E-22 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_26445 3c8f302a1ff32a7303d1b5afb22216a7 165 ProSitePatterns PS00893 Nudix box signature. 46 67 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_26445 3c8f302a1ff32a7303d1b5afb22216a7 165 PRINTS PR00502 NUDIX hydrolase family signature 41 55 7.1E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_26445 3c8f302a1ff32a7303d1b5afb22216a7 165 PRINTS PR00502 NUDIX hydrolase family signature 55 70 7.1E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_26445 3c8f302a1ff32a7303d1b5afb22216a7 165 Gene3D G3DSA:3.90.79.10 1 153 1.7E-29 T 12-10-2018 TL08_26445 3c8f302a1ff32a7303d1b5afb22216a7 165 SUPERFAMILY SSF55811 9 155 5.01E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_10205 5f5e48d7ae3da1913bc5c8da643a6baf 329 SUPERFAMILY SSF52540 74 322 1.45E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10205 5f5e48d7ae3da1913bc5c8da643a6baf 329 SMART SM00382 100 300 2.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_10205 5f5e48d7ae3da1913bc5c8da643a6baf 329 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 301 322 6.6E-11 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TL08_10205 5f5e48d7ae3da1913bc5c8da643a6baf 329 Pfam PF00005 ABC transporter 91 251 2.4E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_10205 5f5e48d7ae3da1913bc5c8da643a6baf 329 Gene3D G3DSA:3.40.50.300 64 321 5.2E-65 T 12-10-2018 TL08_04385 336d103462063f67f65613ece33de136 355 SMART SM00382 27 218 4.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_04385 336d103462063f67f65613ece33de136 355 Pfam PF00005 ABC transporter 19 160 5.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_04385 336d103462063f67f65613ece33de136 355 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_04385 336d103462063f67f65613ece33de136 355 SUPERFAMILY SSF52540 3 240 2.23E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04385 336d103462063f67f65613ece33de136 355 Gene3D G3DSA:3.40.50.300 2 255 2.7E-72 T 12-10-2018 TL08_22900 be7421f6b4e7dfd25bb8bd4d1a0d8ac0 323 SUPERFAMILY SSF51679 1 318 8.77E-73 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_22900 be7421f6b4e7dfd25bb8bd4d1a0d8ac0 323 Gene3D G3DSA:3.20.20.30 1 319 1.3E-82 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_22900 be7421f6b4e7dfd25bb8bd4d1a0d8ac0 323 Pfam PF00296 Luciferase-like monooxygenase 1 294 2.0E-52 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_08865 784894bf15c7d87119c6d859d840e63a 209 Gene3D G3DSA:2.70.70.10 64 200 1.4E-17 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_08865 784894bf15c7d87119c6d859d840e63a 209 SUPERFAMILY SSF51261 68 199 6.28E-16 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_08865 784894bf15c7d87119c6d859d840e63a 209 Pfam PF01551 Peptidase family M23 101 195 6.2E-13 T 12-10-2018 IPR016047 Peptidase M23 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 Gene3D G3DSA:1.10.1160.10 256 339 9.9E-31 T 12-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 Gene3D G3DSA:1.10.10.350 398 498 2.5E-28 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 39 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 208 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 14 26 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 43 56 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 214 222 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 SUPERFAMILY SSF52374 11 323 6.48E-98 T 12-10-2018 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 Gene3D G3DSA:3.40.50.620 11 252 1.5E-89 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 11 491 1.7E-130 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 Gene3D G3DSA:3.90.800.10 80 199 1.5E-89 T 12-10-2018 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 11 327 1.8E-78 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 SUPERFAMILY SSF48163 324 494 1.24E-36 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TL08_22675 32dedc8e5fc63ec172c7a0ac870d4a10 498 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 10 494 31.448 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TL08_07615 590dff039da044157a6a441da9920337 167 SUPERFAMILY SSF55961 21 166 1.12E-32 T 12-10-2018 TL08_07615 590dff039da044157a6a441da9920337 167 Gene3D G3DSA:3.30.530.20 20 167 1.9E-33 T 12-10-2018 IPR023393 START-like domain superfamily TL08_07615 590dff039da044157a6a441da9920337 167 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 30 142 1.1E-16 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TL08_17830 22fb86075a32e6d616e08eaa01934d88 257 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 125 2.8E-10 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 TL08_17830 22fb86075a32e6d616e08eaa01934d88 257 Gene3D G3DSA:3.30.530.20 1 138 1.4E-28 T 12-10-2018 IPR023393 START-like domain superfamily TL08_17830 22fb86075a32e6d616e08eaa01934d88 257 SUPERFAMILY SSF55961 3 136 1.82E-18 T 12-10-2018 TL08_10265 b2a7111ab3e8a51a789928e1c4843a82 331 Gene3D G3DSA:3.40.50.300 1 197 4.2E-68 T 12-10-2018 TL08_10265 b2a7111ab3e8a51a789928e1c4843a82 331 Gene3D G3DSA:3.30.460.10 215 330 6.0E-10 T 12-10-2018 TL08_10265 b2a7111ab3e8a51a789928e1c4843a82 331 SUPERFAMILY SSF52540 3 195 2.11E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10265 b2a7111ab3e8a51a789928e1c4843a82 331 SUPERFAMILY SSF81301 218 328 1.44E-12 T 12-10-2018 TL08_10265 b2a7111ab3e8a51a789928e1c4843a82 331 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 183 1.8E-47 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TL08_10265 b2a7111ab3e8a51a789928e1c4843a82 331 Pfam PF04229 GrpB protein 218 329 2.5E-12 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase TL08_10265 b2a7111ab3e8a51a789928e1c4843a82 331 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 192 25.536 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TL08_10265 b2a7111ab3e8a51a789928e1c4843a82 331 Pfam PF01121 Dephospho-CoA kinase 4 180 1.2E-56 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TL08_09205 d31cd069ae2d36d0921ad4787f148f42 613 Pfam PF00561 alpha/beta hydrolase fold 80 207 2.2E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_09205 d31cd069ae2d36d0921ad4787f148f42 613 Gene3D G3DSA:3.40.50.1820 69 258 7.9E-17 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_09205 d31cd069ae2d36d0921ad4787f148f42 613 Gene3D G3DSA:3.40.50.1820 267 436 8.6E-10 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_09205 d31cd069ae2d36d0921ad4787f148f42 613 Pfam PF08386 TAP-like protein 368 466 3.7E-10 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal TL08_09205 d31cd069ae2d36d0921ad4787f148f42 613 SUPERFAMILY SSF53474 78 436 5.62E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16645 81eb2cb5ba857b0323a043f93f5b3bba 377 SUPERFAMILY SSF56601 13 373 1.07E-52 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_16645 81eb2cb5ba857b0323a043f93f5b3bba 377 Gene3D G3DSA:3.40.710.30 5 377 5.9E-108 T 12-10-2018 TL08_16645 81eb2cb5ba857b0323a043f93f5b3bba 377 Pfam PF00144 Beta-lactamase 21 359 3.4E-48 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_07530 e325cfc16ae0ae6144cd763b38f27c8b 668 SUPERFAMILY SSF51445 212 571 5.37E-79 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_07530 e325cfc16ae0ae6144cd763b38f27c8b 668 SMART SM00642 211 565 2.3E-4 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_07530 e325cfc16ae0ae6144cd763b38f27c8b 668 Gene3D G3DSA:2.60.40.10 16 205 4.2E-54 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_07530 e325cfc16ae0ae6144cd763b38f27c8b 668 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 13 667 44.16 T 12-10-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 TL08_07530 e325cfc16ae0ae6144cd763b38f27c8b 668 Gene3D G3DSA:1.20.58.280 105 186 4.2E-54 T 12-10-2018 TL08_07530 e325cfc16ae0ae6144cd763b38f27c8b 668 Gene3D G3DSA:2.60.40.1180 577 668 1.4E-34 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_07530 e325cfc16ae0ae6144cd763b38f27c8b 668 Gene3D G3DSA:3.20.20.80 206 576 2.2E-163 T 12-10-2018 TL08_07530 e325cfc16ae0ae6144cd763b38f27c8b 668 Pfam PF11896 Domain of unknown function (DUF3416) 15 205 2.9E-51 T 12-10-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 33 596 3.4E-231 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 Gene3D G3DSA:3.40.50.970 395 603 4.5E-71 T 12-10-2018 TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 33 198 9.7E-57 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 Gene3D G3DSA:3.40.50.970 28 205 7.8E-70 T 12-10-2018 TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 458 477 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 SUPERFAMILY SSF52467 216 388 2.65E-62 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 Gene3D G3DSA:3.40.50.1220 217 387 6.9E-65 T 12-10-2018 TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 SUPERFAMILY SSF52518 398 600 4.83E-68 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 573 6.1E-50 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 SUPERFAMILY SSF52518 28 212 6.63E-63 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_22735 ef3fddd320a7154747b23e485e05b3ee 608 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 222 357 6.8E-50 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TL08_21205 a7c38e269f16ae12eedfc7c690dee59c 118 Pfam PF12840 Helix-turn-helix domain 26 81 3.2E-6 T 12-10-2018 TL08_21205 a7c38e269f16ae12eedfc7c690dee59c 118 SUPERFAMILY SSF46785 14 104 3.27E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_21205 a7c38e269f16ae12eedfc7c690dee59c 118 SMART SM00418 26 104 8.8E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21205 a7c38e269f16ae12eedfc7c690dee59c 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 28 43 1.1E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21205 a7c38e269f16ae12eedfc7c690dee59c 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.1E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21205 a7c38e269f16ae12eedfc7c690dee59c 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 1.1E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21205 a7c38e269f16ae12eedfc7c690dee59c 118 Gene3D G3DSA:1.10.10.10 3 115 3.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19365 4c81fde65674949497c39a1512069b3d 790 SUPERFAMILY SSF51445 28 377 7.84E-57 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_19365 4c81fde65674949497c39a1512069b3d 790 Pfam PF01301 Glycosyl hydrolases family 35 38 378 7.0E-50 T 12-10-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_19365 4c81fde65674949497c39a1512069b3d 790 Gene3D G3DSA:3.20.20.80 26 387 2.4E-95 T 12-10-2018 TL08_19365 4c81fde65674949497c39a1512069b3d 790 PRINTS PR00742 Glycosyl hydrolase family 35 signature 115 134 1.0E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_19365 4c81fde65674949497c39a1512069b3d 790 PRINTS PR00742 Glycosyl hydrolase family 35 signature 169 184 1.0E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_19365 4c81fde65674949497c39a1512069b3d 790 PRINTS PR00742 Glycosyl hydrolase family 35 signature 320 335 1.0E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_19365 4c81fde65674949497c39a1512069b3d 790 PRINTS PR00742 Glycosyl hydrolase family 35 signature 39 56 1.0E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_19365 4c81fde65674949497c39a1512069b3d 790 PRINTS PR00742 Glycosyl hydrolase family 35 signature 60 78 1.0E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_19365 4c81fde65674949497c39a1512069b3d 790 PRINTS PR00742 Glycosyl hydrolase family 35 signature 342 358 1.0E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 SMART SM00387 257 369 1.1E-36 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 SUPERFAMILY SSF47384 138 210 1.8E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 Pfam PF00512 His Kinase A (phospho-acceptor) domain 147 211 4.4E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 Gene3D G3DSA:3.30.565.10 219 370 2.1E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 Gene3D G3DSA:1.10.287.130 139 211 4.6E-17 T 12-10-2018 TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 SUPERFAMILY SSF55874 202 367 4.32E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 308 5.2E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 322 5.2E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 347 5.2E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 5.2E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 SMART SM00388 146 212 1.9E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_02295 00fce9d15b066b6e50cde76d6230740f 408 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 367 3.5E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_10195 9e6df7162fd34ccefbf52e3f0712bc98 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 319 5.2E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_04000 696b839894c1d7a87c42787388e8a5e1 289 Gene3D G3DSA:2.120.10.30 1 284 9.6E-96 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_04000 696b839894c1d7a87c42787388e8a5e1 289 SUPERFAMILY SSF63829 11 282 4.14E-63 T 12-10-2018 TL08_04000 696b839894c1d7a87c42787388e8a5e1 289 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 14 253 3.0E-75 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region TL08_04000 696b839894c1d7a87c42787388e8a5e1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 193 210 5.7E-44 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_04000 696b839894c1d7a87c42787388e8a5e1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 130 152 5.7E-44 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_04000 696b839894c1d7a87c42787388e8a5e1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 153 173 5.7E-44 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_04000 696b839894c1d7a87c42787388e8a5e1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 235 253 5.7E-44 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_04000 696b839894c1d7a87c42787388e8a5e1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 5.7E-44 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_04000 696b839894c1d7a87c42787388e8a5e1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 89 110 5.7E-44 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 Pfam PF00270 DEAD/DEAH box helicase 296 450 7.7E-18 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 Gene3D G3DSA:3.40.50.300 476 666 1.5E-51 T 12-10-2018 TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 Gene3D G3DSA:3.40.50.300 216 464 5.0E-80 T 12-10-2018 TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 SUPERFAMILY SSF50249 12 185 1.71E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 Pfam PF00271 Helicase conserved C-terminal domain 553 624 3.0E-18 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 Gene3D G3DSA:2.40.50.140 43 141 2.3E-21 T 12-10-2018 TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 Pfam PF17191 RecG wedge domain 14 139 1.1E-9 T 12-10-2018 IPR033454 RecG, wedge domain TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 SMART SM00487 270 474 3.6E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 SUPERFAMILY SSF52540 293 636 7.22E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 24 701 7.4E-200 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 TL08_22520 18f1cd922e23ebe85332abaaf9031f49 737 SMART SM00490 540 625 6.2E-21 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_15910 9d8b26b711694b5294d27fc61e18cbbf 331 Gene3D G3DSA:3.40.50.720 9 133 2.5E-35 T 12-10-2018 TL08_15910 9d8b26b711694b5294d27fc61e18cbbf 331 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 127 9.6E-23 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_15910 9d8b26b711694b5294d27fc61e18cbbf 331 SUPERFAMILY SSF55347 134 301 8.18E-31 T 12-10-2018 TL08_15910 9d8b26b711694b5294d27fc61e18cbbf 331 Gene3D G3DSA:3.30.360.10 134 330 1.3E-42 T 12-10-2018 TL08_15910 9d8b26b711694b5294d27fc61e18cbbf 331 SUPERFAMILY SSF51735 7 160 2.85E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_12710 7273d3c59e4d7c048a24156036242169 246 Gene3D G3DSA:3.40.50.1000 10 216 2.8E-59 T 12-10-2018 IPR023214 HAD superfamily TL08_12710 7273d3c59e4d7c048a24156036242169 246 SUPERFAMILY SSF56784 8 234 1.38E-51 T 12-10-2018 IPR036412 HAD-like superfamily TL08_12710 7273d3c59e4d7c048a24156036242169 246 Gene3D G3DSA:1.10.720.60 21 105 2.8E-59 T 12-10-2018 TL08_12710 7273d3c59e4d7c048a24156036242169 246 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 6 234 37.006 T 12-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 TL08_12710 7273d3c59e4d7c048a24156036242169 246 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 8 234 5.4E-63 T 12-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 TL08_12790 53b049847192c043928219dc7333bba8 180 Gene3D G3DSA:2.30.110.10 11 178 2.6E-47 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_12790 53b049847192c043928219dc7333bba8 180 SUPERFAMILY SSF50475 20 174 8.83E-43 T 12-10-2018 TL08_12790 53b049847192c043928219dc7333bba8 180 SMART SM00903 29 173 3.1E-44 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TL08_12790 53b049847192c043928219dc7333bba8 180 Pfam PF01613 Flavin reductase like domain 29 174 5.5E-32 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TL08_16170 faeff512b9d7886564c9f67dd82cbb1a 444 Gene3D G3DSA:3.20.20.120 137 398 3.8E-170 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_16170 faeff512b9d7886564c9f67dd82cbb1a 444 Gene3D G3DSA:3.30.390.10 9 412 3.8E-170 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_16170 faeff512b9d7886564c9f67dd82cbb1a 444 SMART SM00922 184 284 6.8E-16 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_16170 faeff512b9d7886564c9f67dd82cbb1a 444 SUPERFAMILY SSF54826 7 135 9.55E-31 T 12-10-2018 TL08_16170 faeff512b9d7886564c9f67dd82cbb1a 444 SUPERFAMILY SSF51604 137 413 4.55E-78 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_16170 faeff512b9d7886564c9f67dd82cbb1a 444 Pfam PF13378 Enolase C-terminal domain-like 189 403 4.3E-39 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_06205 86f64b2887f61775cf28bb688624f88b 570 SUPERFAMILY SSF161098 76 260 3.66E-29 T 12-10-2018 IPR035906 MetI-like superfamily TL08_06205 86f64b2887f61775cf28bb688624f88b 570 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 322 569 4.4E-69 T 12-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 TL08_06205 86f64b2887f61775cf28bb688624f88b 570 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 27 270 9.6E-69 T 12-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 TL08_06205 86f64b2887f61775cf28bb688624f88b 570 SUPERFAMILY SSF161098 374 561 1.31E-30 T 12-10-2018 IPR035906 MetI-like superfamily TL08_06205 86f64b2887f61775cf28bb688624f88b 570 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 399 566 3.2E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_06205 86f64b2887f61775cf28bb688624f88b 570 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 264 8.6E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_06205 86f64b2887f61775cf28bb688624f88b 570 Gene3D G3DSA:1.10.3720.10 75 269 1.1E-25 T 12-10-2018 IPR035906 MetI-like superfamily TL08_06205 86f64b2887f61775cf28bb688624f88b 570 Gene3D G3DSA:1.10.3720.10 370 569 8.2E-29 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15400 c873c2f2baa867929a3381fc73f5b9fa 410 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TL08_15400 c873c2f2baa867929a3381fc73f5b9fa 410 Gene3D G3DSA:3.30.390.10 3 407 3.1E-156 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_15400 c873c2f2baa867929a3381fc73f5b9fa 410 SUPERFAMILY SSF51604 98 394 2.23E-70 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_15400 c873c2f2baa867929a3381fc73f5b9fa 410 Pfam PF13378 Enolase C-terminal domain-like 201 385 1.3E-40 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_15400 c873c2f2baa867929a3381fc73f5b9fa 410 SUPERFAMILY SSF54826 1 112 2.95E-30 T 12-10-2018 TL08_15400 c873c2f2baa867929a3381fc73f5b9fa 410 SMART SM00922 129 265 1.0E-17 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_15400 c873c2f2baa867929a3381fc73f5b9fa 410 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 6.7E-29 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TL08_15400 c873c2f2baa867929a3381fc73f5b9fa 410 Gene3D G3DSA:3.20.20.120 105 376 3.1E-156 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_09730 fdc5fd97b7fb375825b6603a437ffa4b 242 Gene3D G3DSA:3.20.20.70 1 242 3.3E-89 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_09730 fdc5fd97b7fb375825b6603a437ffa4b 242 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 2 242 5.5E-124 T 12-10-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 TL08_09730 fdc5fd97b7fb375825b6603a437ffa4b 242 Pfam PF00977 Histidine biosynthesis protein 5 234 2.5E-60 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TL08_09730 fdc5fd97b7fb375825b6603a437ffa4b 242 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 241 31.987 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TL08_09730 fdc5fd97b7fb375825b6603a437ffa4b 242 SUPERFAMILY SSF51366 3 240 7.85E-60 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TL08_18395 483d51a9b2440b1fdbc872741ea38d6d 134 Gene3D G3DSA:2.30.110.10 3 126 1.6E-27 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_18395 483d51a9b2440b1fdbc872741ea38d6d 134 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 91 1.5E-14 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_18395 483d51a9b2440b1fdbc872741ea38d6d 134 SUPERFAMILY SSF50475 6 131 6.36E-28 T 12-10-2018 TL08_18395 483d51a9b2440b1fdbc872741ea38d6d 134 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 128 2.3E-28 T 12-10-2018 IPR019920 F420-binding domain, putative TL08_03055 8ebb3252d70325de7fc93113368297d0 132 SUPERFAMILY SSF56047 3 132 3.14E-43 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03055 8ebb3252d70325de7fc93113368297d0 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.73 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03055 8ebb3252d70325de7fc93113368297d0 132 Gene3D G3DSA:3.30.1490.10 75 132 2.3E-22 T 12-10-2018 TL08_03055 8ebb3252d70325de7fc93113368297d0 132 Pfam PF00410 Ribosomal protein S8 5 132 9.3E-48 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03055 8ebb3252d70325de7fc93113368297d0 132 Gene3D G3DSA:3.30.1370.30 4 74 8.5E-27 T 12-10-2018 TL08_23820 02c85c120295e10f94fcabcf14fc943e 453 Gene3D G3DSA:3.30.70.360 234 348 5.3E-111 T 12-10-2018 TL08_23820 02c85c120295e10f94fcabcf14fc943e 453 Gene3D G3DSA:3.40.630.10 72 424 5.3E-111 T 12-10-2018 TL08_23820 02c85c120295e10f94fcabcf14fc943e 453 Pfam PF01546 Peptidase family M20/M25/M40 127 435 1.0E-25 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TL08_23820 02c85c120295e10f94fcabcf14fc943e 453 PIRSF PIRSF005962 60 442 4.0E-103 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 TL08_23820 02c85c120295e10f94fcabcf14fc943e 453 SUPERFAMILY SSF55031 235 352 1.15E-20 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TL08_23820 02c85c120295e10f94fcabcf14fc943e 453 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 72 427 8.1E-100 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 TL08_23820 02c85c120295e10f94fcabcf14fc943e 453 SUPERFAMILY SSF53187 61 439 2.2E-72 T 12-10-2018 TL08_05805 eeca9f83bff6984cdfdb7c6ba87a32d0 101 SMART SM00966 36 79 8.9E-7 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TL08_05805 eeca9f83bff6984cdfdb7c6ba87a32d0 101 SUPERFAMILY SSF89447 34 78 4.01E-9 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily TL08_05805 eeca9f83bff6984cdfdb7c6ba87a32d0 101 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 36 64 7.1E-6 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TL08_05805 eeca9f83bff6984cdfdb7c6ba87a32d0 101 Gene3D G3DSA:2.10.260.10 34 73 5.3E-7 T 12-10-2018 TL08_05805 eeca9f83bff6984cdfdb7c6ba87a32d0 101 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 36 73 1.5E-9 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 99 2.5E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 SUPERFAMILY SSF48452 102 266 1.25E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 Gene3D G3DSA:1.25.40.10 104 269 6.9E-43 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 SMART SM00862 19 99 4.9E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 PRINTS PR00364 Disease resistance protein signature 305 320 7.2E-6 T 12-10-2018 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 PRINTS PR00364 Disease resistance protein signature 383 397 7.2E-6 T 12-10-2018 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 PRINTS PR00364 Disease resistance protein signature 471 485 7.2E-6 T 12-10-2018 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 SUPERFAMILY SSF46894 6 99 1.45E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 Pfam PF03704 Bacterial transcriptional activator domain 106 248 1.6E-37 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_05650 d519f466a70535a72a7c2a27205cafee 524 SUPERFAMILY SSF52540 271 500 2.66E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05650 d519f466a70535a72a7c2a27205cafee 524 Gene3D G3DSA:3.40.50.300 270 454 3.4E-24 T 12-10-2018 TL08_05650 d519f466a70535a72a7c2a27205cafee 524 Gene3D G3DSA:1.10.10.10 2 101 4.5E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05650 d519f466a70535a72a7c2a27205cafee 524 SMART SM01043 106 248 1.6E-40 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_22355 89859390294e7310f2e98f651dedfcd5 214 Pfam PF02669 K+-transporting ATPase, c chain 14 206 9.3E-60 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TL08_22355 89859390294e7310f2e98f651dedfcd5 214 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 9 209 30.898 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TL08_22355 89859390294e7310f2e98f651dedfcd5 214 PIRSF PIRSF001296 8 213 9.9E-59 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TL08_22355 89859390294e7310f2e98f651dedfcd5 214 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 11 206 7.0E-48 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TL08_19975 df49134f0ebed391fd3fa5c5ef3dfdd6 313 SUPERFAMILY SSF51430 8 311 1.44E-61 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_19975 df49134f0ebed391fd3fa5c5ef3dfdd6 313 Pfam PF00248 Aldo/keto reductase family 11 309 6.3E-46 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_19975 df49134f0ebed391fd3fa5c5ef3dfdd6 313 Gene3D G3DSA:3.20.20.100 5 313 2.0E-70 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_09245 6e4223051d23de46d2a03d7ce8ff74d5 175 Gene3D G3DSA:3.90.1140.10 1 175 1.2E-29 T 12-10-2018 TL08_09245 6e4223051d23de46d2a03d7ce8ff74d5 175 SUPERFAMILY SSF55144 1 173 2.27E-23 T 12-10-2018 IPR009097 Cyclic phosphodiesterase TL08_09245 6e4223051d23de46d2a03d7ce8ff74d5 175 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 173 15.635 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TL08_09245 6e4223051d23de46d2a03d7ce8ff74d5 175 Pfam PF13563 2'-5' RNA ligase superfamily 15 144 6.4E-12 T 12-10-2018 TL08_26755 bf575d62fe421fa7c7482481600754ce 454 Pfam PF02817 e3 binding domain 171 205 1.3E-12 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TL08_26755 bf575d62fe421fa7c7482481600754ce 454 SUPERFAMILY SSF51230 4 93 1.57E-24 T 12-10-2018 IPR011053 Single hybrid motif TL08_26755 bf575d62fe421fa7c7482481600754ce 454 Gene3D G3DSA:2.40.50.100 1 100 9.8E-23 T 12-10-2018 TL08_26755 bf575d62fe421fa7c7482481600754ce 454 Gene3D G3DSA:4.10.320.10 163 213 6.6E-13 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TL08_26755 bf575d62fe421fa7c7482481600754ce 454 SUPERFAMILY SSF52777 214 451 1.07E-79 T 12-10-2018 TL08_26755 bf575d62fe421fa7c7482481600754ce 454 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TL08_26755 bf575d62fe421fa7c7482481600754ce 454 SUPERFAMILY SSF47005 165 210 1.57E-10 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TL08_26755 bf575d62fe421fa7c7482481600754ce 454 Gene3D G3DSA:3.30.559.10 214 449 5.4E-82 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_26755 bf575d62fe421fa7c7482481600754ce 454 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 224 451 3.2E-80 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TL08_26755 bf575d62fe421fa7c7482481600754ce 454 Pfam PF00364 Biotin-requiring enzyme 6 78 2.1E-19 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TL08_02915 3fac7c112c2528d5dbe04b870bedd593 286 Gene3D G3DSA:1.10.260.40 8 74 1.9E-8 T 12-10-2018 TL08_02915 3fac7c112c2528d5dbe04b870bedd593 286 SMART SM00530 16 71 4.1E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_02915 3fac7c112c2528d5dbe04b870bedd593 286 SUPERFAMILY SSF47413 9 72 1.49E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_02915 3fac7c112c2528d5dbe04b870bedd593 286 Pfam PF13560 Helix-turn-helix domain 13 70 9.8E-10 T 12-10-2018 TL08_03075 9b30dfad30a3e0854625c3e650dcdf36 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 12-10-2018 IPR018038 Ribosomal protein L30, conserved site TL08_03075 9b30dfad30a3e0854625c3e650dcdf36 60 PIRSF PIRSF002211 1 60 7.8E-28 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03075 9b30dfad30a3e0854625c3e650dcdf36 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 8.6E-18 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TL08_03075 9b30dfad30a3e0854625c3e650dcdf36 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.978 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03075 9b30dfad30a3e0854625c3e650dcdf36 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 3.4E-23 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03075 9b30dfad30a3e0854625c3e650dcdf36 60 Gene3D G3DSA:3.30.1390.20 1 60 3.8E-25 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TL08_03075 9b30dfad30a3e0854625c3e650dcdf36 60 SUPERFAMILY SSF55129 1 60 2.22E-21 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TL08_16285 fb3d6757e9f2bbc02629884f19355eef 278 TIGRFAM TIGR04460 endura_MppR: enduracididine biosynthesis enzyme MppR 8 263 2.1E-132 T 12-10-2018 IPR031022 Enduracididine biosynthesis enzyme MppR TL08_16285 fb3d6757e9f2bbc02629884f19355eef 278 SUPERFAMILY SSF160104 22 260 5.62E-37 T 12-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 TL08_16285 fb3d6757e9f2bbc02629884f19355eef 278 Pfam PF06314 Acetoacetate decarboxylase (ADC) 13 263 6.4E-46 T 12-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 TL08_16285 fb3d6757e9f2bbc02629884f19355eef 278 Gene3D G3DSA:2.40.400.10 7 267 5.8E-80 T 12-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 TL08_09900 a34f9c2444459571934371b7e07afe5c 432 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 36 134 9.8E-9 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TL08_09900 a34f9c2444459571934371b7e07afe5c 432 SMART SM00922 197 293 4.2E-26 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_09900 a34f9c2444459571934371b7e07afe5c 432 Gene3D G3DSA:3.30.390.10 1 129 4.1E-53 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_09900 a34f9c2444459571934371b7e07afe5c 432 SUPERFAMILY SSF51604 123 422 2.1E-68 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_09900 a34f9c2444459571934371b7e07afe5c 432 SUPERFAMILY SSF54826 3 136 1.68E-39 T 12-10-2018 TL08_09900 a34f9c2444459571934371b7e07afe5c 432 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 243 274 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TL08_09900 a34f9c2444459571934371b7e07afe5c 432 Pfam PF13378 Enolase C-terminal domain-like 200 412 4.2E-61 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_09900 a34f9c2444459571934371b7e07afe5c 432 Gene3D G3DSA:3.20.20.120 130 430 7.0E-109 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_13315 dc2c02b6087e6d7800a70183aa1da563 144 Gene3D G3DSA:1.10.357.10 1 93 5.4E-22 T 12-10-2018 TL08_13315 dc2c02b6087e6d7800a70183aa1da563 144 Pfam PF00440 Bacterial regulatory proteins, tetR family 3 47 1.2E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_13315 dc2c02b6087e6d7800a70183aa1da563 144 SUPERFAMILY SSF46689 3 61 4.44E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_11695 519577180cf33df37145e2a7cb423ae7 374 SUPERFAMILY SSF51569 9 365 4.64E-74 T 12-10-2018 TL08_11695 519577180cf33df37145e2a7cb423ae7 374 TIGRFAM TIGR00876 tal_mycobact: transaldolase 13 360 6.4E-136 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TL08_11695 519577180cf33df37145e2a7cb423ae7 374 Hamap MF_00493 Transaldolase [tal]. 1 372 154.007 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TL08_11695 519577180cf33df37145e2a7cb423ae7 374 Gene3D G3DSA:3.20.20.70 5 367 2.2E-155 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_11695 519577180cf33df37145e2a7cb423ae7 374 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 17 361 1.4E-78 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TL08_11695 519577180cf33df37145e2a7cb423ae7 374 ProSitePatterns PS01054 Transaldolase signature 1. 43 51 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TL08_11695 519577180cf33df37145e2a7cb423ae7 374 PIRSF PIRSF036915 1 374 6.4E-164 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TL08_04180 85eb64dc865df5ab25c312f1dbcc7337 221 Gene3D G3DSA:1.10.1740.10 8 87 2.7E-19 T 12-10-2018 TL08_04180 85eb64dc865df5ab25c312f1dbcc7337 221 Pfam PF08281 Sigma-70, region 4 126 176 3.7E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_04180 85eb64dc865df5ab25c312f1dbcc7337 221 SUPERFAMILY SSF88659 107 181 1.87E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_04180 85eb64dc865df5ab25c312f1dbcc7337 221 Gene3D G3DSA:1.10.10.10 102 183 2.3E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04180 85eb64dc865df5ab25c312f1dbcc7337 221 SUPERFAMILY SSF88946 13 93 3.34E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_04180 85eb64dc865df5ab25c312f1dbcc7337 221 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 180 9.0E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_04180 85eb64dc865df5ab25c312f1dbcc7337 221 Pfam PF04542 Sigma-70 region 2 23 91 3.6E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_16355 9675091077e469bc5d789d1e7f690a0c 349 SUPERFAMILY SSF51197 43 332 1.24E-79 T 12-10-2018 TL08_16355 9675091077e469bc5d789d1e7f690a0c 349 Gene3D G3DSA:3.60.130.10 16 333 2.1E-95 T 12-10-2018 TL08_16355 9675091077e469bc5d789d1e7f690a0c 349 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 48 331 7.4E-43 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 SMART SM01043 78 223 2.7E-40 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 SUPERFAMILY SSF46894 6 71 1.42E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 PRINTS PR00364 Disease resistance protein signature 433 447 6.5E-9 T 12-10-2018 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 PRINTS PR00364 Disease resistance protein signature 276 291 6.5E-9 T 12-10-2018 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 PRINTS PR00364 Disease resistance protein signature 348 362 6.5E-9 T 12-10-2018 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 SUPERFAMILY SSF52540 246 450 2.23E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 Gene3D G3DSA:1.10.10.10 1 73 1.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 SUPERFAMILY SSF48452 76 239 2.7E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 Gene3D G3DSA:1.25.40.10 75 240 9.7E-39 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 SMART SM00862 2 71 2.4E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 Gene3D G3DSA:3.40.50.300 241 391 5.2E-23 T 12-10-2018 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 Pfam PF00486 Transcriptional regulatory protein, C terminal 7 71 5.3E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 Pfam PF00931 NB-ARC domain 268 449 2.7E-7 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_05205 9a94afae59ecdf5de95fa65ee7221bb5 591 Pfam PF03704 Bacterial transcriptional activator domain 78 223 1.5E-36 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_10945 f37cd4ecdbb5e5c93bc29a6a9391b7cb 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10945 f37cd4ecdbb5e5c93bc29a6a9391b7cb 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 2 15 1.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10945 f37cd4ecdbb5e5c93bc29a6a9391b7cb 187 SUPERFAMILY SSF46689 2 68 5.99E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_10945 f37cd4ecdbb5e5c93bc29a6a9391b7cb 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 3 46 2.9E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10945 f37cd4ecdbb5e5c93bc29a6a9391b7cb 187 Gene3D G3DSA:1.10.357.10 1 185 6.2E-28 T 12-10-2018 TL08_16960 1f21c0ec7172c5e55cf4804b7eb852d4 128 Gene3D G3DSA:3.30.1310.10 22 120 8.8E-8 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_16960 1f21c0ec7172c5e55cf4804b7eb852d4 128 SUPERFAMILY SSF82607 25 116 6.41E-8 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_16960 1f21c0ec7172c5e55cf4804b7eb852d4 128 Pfam PF02575 YbaB/EbfC DNA-binding family 32 116 6.8E-10 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_21260 887a81bbd57f320003fc5499aa95c446 245 SUPERFAMILY SSF52317 37 212 5.41E-20 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_21260 887a81bbd57f320003fc5499aa95c446 245 Pfam PF03575 Peptidase family S51 40 209 8.2E-23 T 12-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 TL08_21260 887a81bbd57f320003fc5499aa95c446 245 Gene3D G3DSA:3.40.50.880 28 212 5.4E-26 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_01680 1e1543946035ba4193feb0f1635b87aa 127 Pfam PF02152 Dihydroneopterin aldolase 5 115 5.1E-33 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TL08_01680 1e1543946035ba4193feb0f1635b87aa 127 SUPERFAMILY SSF55620 3 119 3.95E-36 T 12-10-2018 TL08_01680 1e1543946035ba4193feb0f1635b87aa 127 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 3.2E-37 T 12-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TL08_01680 1e1543946035ba4193feb0f1635b87aa 127 SMART SM00905 5 117 5.5E-48 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TL08_01680 1e1543946035ba4193feb0f1635b87aa 127 TIGRFAM TIGR00526 folB_dom: FolB domain 3 120 7.6E-34 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TL08_01680 1e1543946035ba4193feb0f1635b87aa 127 Gene3D G3DSA:3.30.1130.10 1 119 7.0E-44 T 12-10-2018 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 1 350 3.1E-105 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 Pfam PF07478 D-ala D-ala ligase C-terminus 145 348 1.0E-65 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 351 38.492 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 PIRSF PIRSF039102 1 356 2.7E-107 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 105 116 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 SUPERFAMILY SSF52440 1 136 8.34E-34 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 Gene3D G3DSA:3.30.470.20 220 356 3.0E-43 T 12-10-2018 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 293 321 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 Pfam PF01820 D-ala D-ala ligase N-terminus 1 127 3.1E-32 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 Gene3D G3DSA:3.40.50.20 1 126 2.2E-39 T 12-10-2018 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 SUPERFAMILY SSF56059 138 351 1.94E-54 T 12-10-2018 TL08_22590 9a863efa2abeef77e8690b84802d96a5 358 Gene3D G3DSA:3.30.1490.20 154 219 4.2E-26 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TL08_06655 dc5aa720296b30ec7f575beea24060ee 571 Pfam PF00005 ABC transporter 386 520 8.9E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_06655 dc5aa720296b30ec7f575beea24060ee 571 SMART SM00382 60 261 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_06655 dc5aa720296b30ec7f575beea24060ee 571 SMART SM00382 393 561 2.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_06655 dc5aa720296b30ec7f575beea24060ee 571 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_06655 dc5aa720296b30ec7f575beea24060ee 571 Pfam PF00005 ABC transporter 51 216 4.9E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_06655 dc5aa720296b30ec7f575beea24060ee 571 Gene3D G3DSA:3.40.50.300 40 312 3.0E-49 T 12-10-2018 TL08_06655 dc5aa720296b30ec7f575beea24060ee 571 SUPERFAMILY SSF52540 29 291 3.1E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06655 dc5aa720296b30ec7f575beea24060ee 571 SUPERFAMILY SSF52540 386 557 1.83E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06655 dc5aa720296b30ec7f575beea24060ee 571 Gene3D G3DSA:3.40.50.300 374 561 2.2E-36 T 12-10-2018 TL08_05900 067a127853deb655d7d1c1a4367ee98d 375 Pfam PF04055 Radical SAM superfamily 21 162 1.1E-22 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_05900 067a127853deb655d7d1c1a4367ee98d 375 Pfam PF13394 4Fe-4S single cluster domain 21 109 7.7E-10 T 12-10-2018 TL08_05900 067a127853deb655d7d1c1a4367ee98d 375 PIRSF PIRSF037420 8 360 3.2E-37 T 12-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TL08_05900 067a127853deb655d7d1c1a4367ee98d 375 SUPERFAMILY SSF102114 9 356 2.88E-52 T 12-10-2018 TL08_05900 067a127853deb655d7d1c1a4367ee98d 375 Pfam PF13186 Iron-sulfur cluster-binding domain 291 352 1.5E-10 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain TL08_05900 067a127853deb655d7d1c1a4367ee98d 375 Gene3D G3DSA:3.20.20.70 10 346 9.2E-47 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_08445 1043237b197f9eaad2a550ed54257a78 450 Gene3D G3DSA:3.40.50.150 113 440 2.7E-52 T 12-10-2018 TL08_08445 1043237b197f9eaad2a550ed54257a78 450 SUPERFAMILY SSF53335 99 445 1.48E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_08445 1043237b197f9eaad2a550ed54257a78 450 SUPERFAMILY SSF50249 38 97 1.03E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_08445 1043237b197f9eaad2a550ed54257a78 450 Gene3D G3DSA:3.40.1350.30 160 262 2.7E-52 T 12-10-2018 TL08_08445 1043237b197f9eaad2a550ed54257a78 450 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 372 444 4.4E-8 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TL08_08445 1043237b197f9eaad2a550ed54257a78 450 Gene3D G3DSA:2.40.50.140 27 109 4.4E-20 T 12-10-2018 TL08_08445 1043237b197f9eaad2a550ed54257a78 450 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 428 438 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site TL08_08445 1043237b197f9eaad2a550ed54257a78 450 Pfam PF01938 TRAM domain 36 82 1.0E-9 T 12-10-2018 IPR002792 TRAM domain TL08_08960 b6be79dbccf67463de0baa3b5f94d36c 121 Pfam PF11255 Protein of unknown function (DUF3054) 12 112 3.4E-25 T 12-10-2018 IPR021414 Protein of unknown function DUF3054 TL08_07480 3930a4a143492908e96a697c21bc0699 474 Hamap MF_01113 DNA polymerase IV [dinB]. 1 353 31.134 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 TL08_07480 3930a4a143492908e96a697c21bc0699 474 Gene3D G3DSA:2.30.40.20 18 69 1.3E-46 T 12-10-2018 TL08_07480 3930a4a143492908e96a697c21bc0699 474 SUPERFAMILY SSF56672 1 236 3.11E-65 T 12-10-2018 TL08_07480 3930a4a143492908e96a697c21bc0699 474 SUPERFAMILY SSF100879 237 336 1.9E-21 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TL08_07480 3930a4a143492908e96a697c21bc0699 474 Pfam PF00817 impB/mucB/samB family 4 151 7.6E-36 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TL08_07480 3930a4a143492908e96a697c21bc0699 474 Gene3D G3DSA:1.10.150.20 167 234 1.8E-16 T 12-10-2018 TL08_07480 3930a4a143492908e96a697c21bc0699 474 Pfam PF11798 IMS family HHH motif 163 194 4.4E-6 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 TL08_07480 3930a4a143492908e96a697c21bc0699 474 Gene3D G3DSA:3.30.70.270 1 161 1.3E-46 T 12-10-2018 TL08_07480 3930a4a143492908e96a697c21bc0699 474 Pfam PF11799 impB/mucB/samB family C-terminal domain 231 343 1.1E-19 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TL08_07480 3930a4a143492908e96a697c21bc0699 474 Gene3D G3DSA:3.30.1490.100 235 347 5.7E-21 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 TL08_10900 a0b130d478e7c101f0f56c8ebdb54e80 362 TIGRFAM TIGR00109 hemH: ferrochelatase 10 316 2.9E-43 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TL08_10900 a0b130d478e7c101f0f56c8ebdb54e80 362 ProSitePatterns PS00534 Ferrochelatase signature. 181 200 - T 12-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TL08_10900 a0b130d478e7c101f0f56c8ebdb54e80 362 Hamap MF_00323 Ferrochelatase [hemH]. 7 318 32.045 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TL08_10900 a0b130d478e7c101f0f56c8ebdb54e80 362 Gene3D G3DSA:3.40.50.1400 11 314 1.4E-117 T 12-10-2018 TL08_10900 a0b130d478e7c101f0f56c8ebdb54e80 362 SUPERFAMILY SSF53800 7 324 5.23E-86 T 12-10-2018 TL08_10900 a0b130d478e7c101f0f56c8ebdb54e80 362 Pfam PF00762 Ferrochelatase 9 316 1.9E-97 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TL08_10900 a0b130d478e7c101f0f56c8ebdb54e80 362 Gene3D G3DSA:3.40.50.1400 151 299 1.4E-117 T 12-10-2018 TL08_22490 5d62f06f95a97ddb8f3df0e0ef17ccc5 599 Pfam PF04183 IucA / IucC family 139 389 7.1E-72 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 TL08_22490 5d62f06f95a97ddb8f3df0e0ef17ccc5 599 Gene3D G3DSA:1.10.274.90 1 128 4.6E-46 T 12-10-2018 TL08_22490 5d62f06f95a97ddb8f3df0e0ef17ccc5 599 Gene3D G3DSA:1.10.510.40 378 586 5.9E-69 T 12-10-2018 TL08_22490 5d62f06f95a97ddb8f3df0e0ef17ccc5 599 Pfam PF06276 Ferric iron reductase FhuF-like transporter 411 568 2.5E-40 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain TL08_14870 3643dd03521c65a2f12da11cfb9fbfb7 543 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 62 477 4.8E-120 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_14870 3643dd03521c65a2f12da11cfb9fbfb7 543 Gene3D G3DSA:3.40.50.12780 29 445 2.5E-116 T 12-10-2018 TL08_14870 3643dd03521c65a2f12da11cfb9fbfb7 543 Pfam PF00501 AMP-binding enzyme 39 452 5.4E-84 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_14870 3643dd03521c65a2f12da11cfb9fbfb7 543 Gene3D G3DSA:3.30.300.30 447 543 3.0E-29 T 12-10-2018 TL08_14870 3643dd03521c65a2f12da11cfb9fbfb7 543 SUPERFAMILY SSF56801 20 542 4.19E-130 T 12-10-2018 TL08_14870 3643dd03521c65a2f12da11cfb9fbfb7 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 461 535 2.9E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_12545 a5308c2b67c6a7fa6f58bf877155f072 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 232 2.4E-18 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TL08_12545 a5308c2b67c6a7fa6f58bf877155f072 398 SUPERFAMILY SSF56645 2 257 4.84E-55 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_12545 a5308c2b67c6a7fa6f58bf877155f072 398 Gene3D G3DSA:1.20.140.10 245 397 1.1E-39 T 12-10-2018 TL08_12545 a5308c2b67c6a7fa6f58bf877155f072 398 SUPERFAMILY SSF47203 243 396 3.22E-42 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_12545 a5308c2b67c6a7fa6f58bf877155f072 398 Gene3D G3DSA:2.40.110.10 129 244 3.9E-43 T 12-10-2018 TL08_12545 a5308c2b67c6a7fa6f58bf877155f072 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 394 8.9E-38 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TL08_12545 a5308c2b67c6a7fa6f58bf877155f072 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 126 1.3E-9 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TL08_12545 a5308c2b67c6a7fa6f58bf877155f072 398 Gene3D G3DSA:1.10.540.10 1 128 7.3E-43 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_23155 ea62350857a5efaf56b670b9de46770f 178 SUPERFAMILY SSF55729 9 174 2.74E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_23155 ea62350857a5efaf56b670b9de46770f 178 Gene3D G3DSA:3.40.630.30 9 174 5.4E-41 T 12-10-2018 TL08_23155 ea62350857a5efaf56b670b9de46770f 178 Pfam PF00583 Acetyltransferase (GNAT) family 40 147 2.2E-12 T 12-10-2018 IPR000182 GNAT domain TL08_02160 86ce1f1ee38a8bf035258e4073fd89e0 425 SMART SM00387 335 425 0.0044 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_02160 86ce1f1ee38a8bf035258e4073fd89e0 425 Pfam PF13796 Putative sensor 19 189 4.0E-19 T 12-10-2018 IPR025828 Putative sensor domain TL08_02160 86ce1f1ee38a8bf035258e4073fd89e0 425 Gene3D G3DSA:3.30.565.10 314 423 3.9E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_02160 86ce1f1ee38a8bf035258e4073fd89e0 425 SUPERFAMILY SSF55874 334 422 1.72E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_02160 86ce1f1ee38a8bf035258e4073fd89e0 425 Pfam PF07730 Histidine kinase 218 283 3.1E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 Pfam PF00067 Cytochrome P450 293 384 3.0E-12 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 Pfam PF00067 Cytochrome P450 97 286 7.3E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 363 372 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 SUPERFAMILY SSF48264 25 416 1.7E-88 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 Gene3D G3DSA:1.10.630.10 17 418 4.6E-125 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 PRINTS PR00359 B-class P450 signature 170 185 2.5E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 PRINTS PR00359 B-class P450 signature 295 306 2.5E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 PRINTS PR00359 B-class P450 signature 153 169 2.5E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 PRINTS PR00359 B-class P450 signature 213 235 2.5E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 PRINTS PR00359 B-class P450 signature 312 339 2.5E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 PRINTS PR00359 B-class P450 signature 361 370 2.5E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 PRINTS PR00359 B-class P450 signature 370 381 2.5E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 PRINTS PR00359 B-class P450 signature 340 355 2.5E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_00415 89516b9a3bf7553ee75e3187d5361e53 418 PRINTS PR00359 B-class P450 signature 103 114 2.5E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09335 1da533638ad63872ba75223d20f9020c 252 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 1 240 26.017 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TL08_09335 1da533638ad63872ba75223d20f9020c 252 SUPERFAMILY SSF69796 34 235 3.27E-61 T 12-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TL08_09335 1da533638ad63872ba75223d20f9020c 252 Pfam PF02511 Thymidylate synthase complementing protein 33 227 2.2E-54 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TL08_09335 1da533638ad63872ba75223d20f9020c 252 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 10 232 8.9E-60 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TL08_09335 1da533638ad63872ba75223d20f9020c 252 Gene3D G3DSA:3.30.70.3180 61 160 1.5E-23 T 12-10-2018 TL08_09335 1da533638ad63872ba75223d20f9020c 252 Gene3D G3DSA:3.30.70.3180 161 252 3.1E-34 T 12-10-2018 TL08_05225 35f44483f269422dede7ef42f8bcb2a6 384 Gene3D G3DSA:3.30.565.10 256 380 6.9E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_05225 35f44483f269422dede7ef42f8bcb2a6 384 SUPERFAMILY SSF55874 265 379 1.17E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_05225 35f44483f269422dede7ef42f8bcb2a6 384 Pfam PF07730 Histidine kinase 182 246 3.4E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_13535 335f998d4b24df7f2055c35ffd3d3d00 314 Pfam PF04116 Fatty acid hydroxylase superfamily 134 264 1.9E-24 T 12-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 SMART SM00345 8 67 8.7E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 7.7E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 7.7E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 Pfam PF07729 FCD domain 96 211 2.9E-22 T 12-10-2018 IPR011711 GntR, C-terminal TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 SMART SM00895 96 213 1.7E-15 T 12-10-2018 IPR011711 GntR, C-terminal TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 Gene3D G3DSA:1.10.10.10 5 73 2.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 SUPERFAMILY SSF46785 7 76 7.61E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 1.3E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 SUPERFAMILY SSF48008 94 219 7.59E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_09835 4fd333724cf42f1a44b25647ace255d6 225 Gene3D G3DSA:1.20.120.530 94 222 2.5E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_24025 f2973e591b657723a16e29680ba6bcc7 663 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 182 194 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_24025 f2973e591b657723a16e29680ba6bcc7 663 Gene3D G3DSA:1.10.510.10 145 328 8.1E-42 T 12-10-2018 TL08_24025 f2973e591b657723a16e29680ba6bcc7 663 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 65 88 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_24025 f2973e591b657723a16e29680ba6bcc7 663 Pfam PF00069 Protein kinase domain 59 267 7.7E-46 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_24025 f2973e591b657723a16e29680ba6bcc7 663 SUPERFAMILY SSF56112 42 322 2.43E-68 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_24025 f2973e591b657723a16e29680ba6bcc7 663 Gene3D G3DSA:3.30.200.20 48 142 2.7E-28 T 12-10-2018 TL08_24025 f2973e591b657723a16e29680ba6bcc7 663 SMART SM00220 59 318 1.6E-55 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_25575 f7d1cf83982180116a153d7d2ca1f53f 205 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 126 203 1.5E-29 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TL08_25575 f7d1cf83982180116a153d7d2ca1f53f 205 SUPERFAMILY SSF46767 125 203 5.62E-27 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TL08_25575 f7d1cf83982180116a153d7d2ca1f53f 205 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 174 180 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TL08_25575 f7d1cf83982180116a153d7d2ca1f53f 205 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 126 204 2.2E-27 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TL08_25575 f7d1cf83982180116a153d7d2ca1f53f 205 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 44 120 5.0E-11 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TL08_25575 f7d1cf83982180116a153d7d2ca1f53f 205 Gene3D G3DSA:3.30.160.70 43 119 3.2E-20 T 12-10-2018 TL08_25575 f7d1cf83982180116a153d7d2ca1f53f 205 Gene3D G3DSA:1.10.10.10 123 205 3.0E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25575 f7d1cf83982180116a153d7d2ca1f53f 205 SUPERFAMILY SSF53155 43 121 2.35E-18 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TL08_25575 f7d1cf83982180116a153d7d2ca1f53f 205 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 47 204 36.755 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 TL08_12475 13a17a83301d079de21b101a545513d1 314 SUPERFAMILY SSF53613 1 302 1.31E-72 T 12-10-2018 IPR029056 Ribokinase-like TL08_12475 13a17a83301d079de21b101a545513d1 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TL08_12475 13a17a83301d079de21b101a545513d1 314 Pfam PF00294 pfkB family carbohydrate kinase 19 298 3.0E-45 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_12475 13a17a83301d079de21b101a545513d1 314 Gene3D G3DSA:3.40.1190.20 1 306 4.8E-83 T 12-10-2018 IPR029056 Ribokinase-like TL08_17380 8c53f8243fd62c511a803ed832a2c655 441 Pfam PF16499 Alpha galactosidase A 174 353 2.5E-17 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_17380 8c53f8243fd62c511a803ed832a2c655 441 Gene3D G3DSA:3.20.20.70 8 354 1.4E-126 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_17380 8c53f8243fd62c511a803ed832a2c655 441 PRINTS PR00740 Glycosyl hydrolase family 27 signature 21 40 6.9E-13 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_17380 8c53f8243fd62c511a803ed832a2c655 441 PRINTS PR00740 Glycosyl hydrolase family 27 signature 209 227 6.9E-13 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_17380 8c53f8243fd62c511a803ed832a2c655 441 PRINTS PR00740 Glycosyl hydrolase family 27 signature 115 136 6.9E-13 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_17380 8c53f8243fd62c511a803ed832a2c655 441 PRINTS PR00740 Glycosyl hydrolase family 27 signature 309 330 6.9E-13 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_17380 8c53f8243fd62c511a803ed832a2c655 441 SUPERFAMILY SSF51011 360 438 6.23E-5 T 12-10-2018 TL08_17380 8c53f8243fd62c511a803ed832a2c655 441 SUPERFAMILY SSF51445 24 353 9.83E-62 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_17380 8c53f8243fd62c511a803ed832a2c655 441 Gene3D G3DSA:2.60.40.1180 356 441 4.5E-9 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_18625 5fcd65ff544a5e760575ac50f4203eae 192 Gene3D G3DSA:1.10.357.10 51 186 7.9E-28 T 12-10-2018 TL08_18625 5fcd65ff544a5e760575ac50f4203eae 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 2.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18625 5fcd65ff544a5e760575ac50f4203eae 192 Pfam PF13305 WHG domain 85 159 8.2E-6 T 12-10-2018 IPR025996 WHG domain TL08_18625 5fcd65ff544a5e760575ac50f4203eae 192 SUPERFAMILY SSF46689 3 74 1.55E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18625 5fcd65ff544a5e760575ac50f4203eae 192 Gene3D G3DSA:1.10.10.60 1 49 9.1E-19 T 12-10-2018 TL08_18625 5fcd65ff544a5e760575ac50f4203eae 192 SUPERFAMILY SSF48498 78 184 1.78E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_25915 a64f5b642d5f6c09a830992702f5c850 281 Gene3D G3DSA:3.40.50.1820 9 272 4.4E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_25915 a64f5b642d5f6c09a830992702f5c850 281 Pfam PF12146 Serine aminopeptidase, S33 47 170 1.7E-11 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 TL08_25915 a64f5b642d5f6c09a830992702f5c850 281 SUPERFAMILY SSF53474 39 264 1.89E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_27075 2336be8f4356709bf523bb626b5d60f7 164 Pfam PF04542 Sigma-70 region 2 2 52 1.7E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_27075 2336be8f4356709bf523bb626b5d60f7 164 Pfam PF08281 Sigma-70, region 4 80 132 5.5E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_27075 2336be8f4356709bf523bb626b5d60f7 164 SUPERFAMILY SSF88946 2 62 2.75E-16 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_27075 2336be8f4356709bf523bb626b5d60f7 164 Gene3D G3DSA:1.10.1740.10 1 54 3.5E-17 T 12-10-2018 TL08_27075 2336be8f4356709bf523bb626b5d60f7 164 SUPERFAMILY SSF88659 72 137 2.83E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_27075 2336be8f4356709bf523bb626b5d60f7 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 135 2.1E-26 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_27075 2336be8f4356709bf523bb626b5d60f7 164 Gene3D G3DSA:1.10.10.10 60 139 3.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_14425 fe802a9f001e9e2e3921af9cf748c6eb 648 SUPERFAMILY SSF51735 10 142 5.76E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14425 fe802a9f001e9e2e3921af9cf748c6eb 648 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 125 7.5E-19 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_14425 fe802a9f001e9e2e3921af9cf748c6eb 648 Gene3D G3DSA:3.40.50.720 10 351 1.2E-123 T 12-10-2018 TL08_14425 fe802a9f001e9e2e3921af9cf748c6eb 648 SUPERFAMILY SSF53335 404 618 1.86E-20 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_14425 fe802a9f001e9e2e3921af9cf748c6eb 648 Gene3D G3DSA:3.40.50.150 404 624 3.3E-19 T 12-10-2018 TL08_14425 fe802a9f001e9e2e3921af9cf748c6eb 648 TIGRFAM TIGR01761 thiaz-red: thiazolinyl imide reductase 10 360 1.8E-99 T 12-10-2018 IPR010091 Thiazolinyl imide reductase TL08_14425 fe802a9f001e9e2e3921af9cf748c6eb 648 Gene3D G3DSA:3.30.360.10 129 303 1.2E-123 T 12-10-2018 TL08_14425 fe802a9f001e9e2e3921af9cf748c6eb 648 Pfam PF13649 Methyltransferase domain 441 536 8.4E-8 T 12-10-2018 TL08_16855 94d58e436697a0b0f22b09acbd002c80 1182 SUPERFAMILY SSF52540 440 823 5.44E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_16855 94d58e436697a0b0f22b09acbd002c80 1182 Pfam PF08463 EcoEI R protein C-terminal 1004 1181 1.9E-28 T 12-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 TL08_16855 94d58e436697a0b0f22b09acbd002c80 1182 SMART SM00487 420 643 3.2E-15 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_16855 94d58e436697a0b0f22b09acbd002c80 1182 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 300 377 7.1E-8 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 TL08_16855 94d58e436697a0b0f22b09acbd002c80 1182 Pfam PF04851 Type III restriction enzyme, res subunit 424 611 1.3E-32 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TL08_16855 94d58e436697a0b0f22b09acbd002c80 1182 Gene3D G3DSA:3.40.50.300 626 863 4.9E-42 T 12-10-2018 TL08_16855 94d58e436697a0b0f22b09acbd002c80 1182 Gene3D G3DSA:3.40.50.300 414 622 3.6E-37 T 12-10-2018 TL08_16855 94d58e436697a0b0f22b09acbd002c80 1182 Gene3D G3DSA:3.90.1570.30 241 399 4.6E-10 T 12-10-2018 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 Pfam PF01479 S4 domain 92 138 7.7E-20 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 34.703 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 3.9E-30 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 Gene3D G3DSA:1.10.1050.10 6 201 7.6E-74 T 12-10-2018 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 SMART SM00363 91 156 8.5E-16 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 Gene3D G3DSA:3.10.290.10 90 186 7.6E-74 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 9.8E-79 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 SMART SM01390 3 90 1.4E-44 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 SUPERFAMILY SSF55174 3 201 9.55E-66 T 12-10-2018 TL08_03130 47fd14d13fabf6b087dec041076e4500 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_12125 6f8cdd25f4b348e0d1477effdcd5048a 433 Pfam PF13530 Sterol carrier protein domain 211 429 4.8E-51 T 12-10-2018 IPR025559 Enhanced intracellular survival protein domain TL08_12125 6f8cdd25f4b348e0d1477effdcd5048a 433 Hamap MF_01812 N-acetyltransferase Eis [eis]. 34 433 32.292 T 12-10-2018 IPR022902 N-acetyltransferase Eis TL08_12125 6f8cdd25f4b348e0d1477effdcd5048a 433 Gene3D G3DSA:3.40.630.30 32 166 2.3E-30 T 12-10-2018 TL08_12125 6f8cdd25f4b348e0d1477effdcd5048a 433 Pfam PF13527 Acetyltransferase (GNAT) domain 37 162 1.2E-25 T 12-10-2018 TL08_12125 6f8cdd25f4b348e0d1477effdcd5048a 433 SUPERFAMILY SSF55718 332 433 3.65E-20 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TL08_12125 6f8cdd25f4b348e0d1477effdcd5048a 433 SUPERFAMILY SSF55729 37 331 2.38E-52 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_12125 6f8cdd25f4b348e0d1477effdcd5048a 433 Gene3D G3DSA:3.30.1050.10 330 424 5.9E-24 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TL08_12125 6f8cdd25f4b348e0d1477effdcd5048a 433 Gene3D G3DSA:3.40.630.30 167 324 1.1E-40 T 12-10-2018 TL08_11365 abc26dbeb48ea76f0ee486d59b065085 182 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 29 166 22.588 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TL08_11365 abc26dbeb48ea76f0ee486d59b065085 182 Gene3D G3DSA:3.30.420.140 28 175 1.3E-42 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 TL08_11365 abc26dbeb48ea76f0ee486d59b065085 182 Pfam PF03652 Holliday junction resolvase 30 163 1.6E-41 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TL08_11365 abc26dbeb48ea76f0ee486d59b065085 182 SUPERFAMILY SSF53098 29 165 4.25E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_11365 abc26dbeb48ea76f0ee486d59b065085 182 SMART SM00732 29 131 2.4E-23 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 TL08_11365 abc26dbeb48ea76f0ee486d59b065085 182 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 32 163 3.8E-27 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TL08_09580 8d6f018cdb9889a5101e76f51b17e6ac 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 3.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_09580 8d6f018cdb9889a5101e76f51b17e6ac 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 3.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_09580 8d6f018cdb9889a5101e76f51b17e6ac 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 81 2.0E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_09580 8d6f018cdb9889a5101e76f51b17e6ac 224 SUPERFAMILY SSF48498 104 210 2.08E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_09580 8d6f018cdb9889a5101e76f51b17e6ac 224 SUPERFAMILY SSF46689 26 107 5.13E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_09580 8d6f018cdb9889a5101e76f51b17e6ac 224 Gene3D G3DSA:1.10.357.10 79 216 7.0E-16 T 12-10-2018 TL08_09580 8d6f018cdb9889a5101e76f51b17e6ac 224 Gene3D G3DSA:1.10.10.60 14 78 5.2E-15 T 12-10-2018 TL08_22345 29116643272caebe0850084d618235eb 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 3.8E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_22345 29116643272caebe0850084d618235eb 225 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_22345 29116643272caebe0850084d618235eb 225 SUPERFAMILY SSF52172 1 180 4.84E-41 T 12-10-2018 IPR011006 CheY-like superfamily TL08_22345 29116643272caebe0850084d618235eb 225 Gene3D G3DSA:3.40.50.2300 1 128 4.2E-36 T 12-10-2018 TL08_22345 29116643272caebe0850084d618235eb 225 SMART SM00448 2 112 4.0E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_22345 29116643272caebe0850084d618235eb 225 Gene3D G3DSA:1.10.10.10 129 225 6.3E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22345 29116643272caebe0850084d618235eb 225 SMART SM00862 147 223 1.0E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_01620 27119e44ee7a870f6b2a512a63d09982 298 Pfam PF12697 Alpha/beta hydrolase family 75 238 5.6E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_01620 27119e44ee7a870f6b2a512a63d09982 298 Gene3D G3DSA:3.40.50.1820 57 281 2.4E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_01620 27119e44ee7a870f6b2a512a63d09982 298 SUPERFAMILY SSF53474 44 281 3.98E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06930 12322b21c4d45ec7775284e83be693c2 186 Pfam PF08281 Sigma-70, region 4 126 177 1.5E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_06930 12322b21c4d45ec7775284e83be693c2 186 SUPERFAMILY SSF88659 118 181 1.85E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_06930 12322b21c4d45ec7775284e83be693c2 186 SUPERFAMILY SSF88946 5 103 1.02E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_06930 12322b21c4d45ec7775284e83be693c2 186 Gene3D G3DSA:1.10.10.10 120 186 6.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06930 12322b21c4d45ec7775284e83be693c2 186 Pfam PF04542 Sigma-70 region 2 27 93 4.3E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_06930 12322b21c4d45ec7775284e83be693c2 186 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 181 2.4E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_06930 12322b21c4d45ec7775284e83be693c2 186 Gene3D G3DSA:1.10.1740.10 2 115 1.2E-17 T 12-10-2018 TL08_25320 9dc6cf8469364095deeb5bd34f89c97a 1103 Pfam PF00672 HAMP domain 385 452 1.6E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_25320 9dc6cf8469364095deeb5bd34f89c97a 1103 SMART SM00387 567 679 2.7E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_25320 9dc6cf8469364095deeb5bd34f89c97a 1103 SUPERFAMILY SSF55874 554 681 2.49E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_25320 9dc6cf8469364095deeb5bd34f89c97a 1103 Pfam PF08376 Nitrate and nitrite sensing 110 347 6.1E-39 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein TL08_25320 9dc6cf8469364095deeb5bd34f89c97a 1103 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 571 671 1.4E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_25320 9dc6cf8469364095deeb5bd34f89c97a 1103 SMART SM00304 385 455 0.0015 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_25320 9dc6cf8469364095deeb5bd34f89c97a 1103 Gene3D G3DSA:3.30.565.10 504 670 4.7E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_14740 ab19e4e9513e9a91e145512831460acc 280 Pfam PF00106 short chain dehydrogenase 3 187 3.4E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14740 ab19e4e9513e9a91e145512831460acc 280 SUPERFAMILY SSF51735 2 252 4.6E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14740 ab19e4e9513e9a91e145512831460acc 280 Gene3D G3DSA:3.40.50.720 2 277 6.1E-75 T 12-10-2018 TL08_14740 ab19e4e9513e9a91e145512831460acc 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.5E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14740 ab19e4e9513e9a91e145512831460acc 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.5E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14740 ab19e4e9513e9a91e145512831460acc 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.5E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14740 ab19e4e9513e9a91e145512831460acc 280 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 188 0.0023 T 12-10-2018 TL08_14740 ab19e4e9513e9a91e145512831460acc 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 8.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14740 ab19e4e9513e9a91e145512831460acc 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14740 ab19e4e9513e9a91e145512831460acc 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 8.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14740 ab19e4e9513e9a91e145512831460acc 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 8.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14740 ab19e4e9513e9a91e145512831460acc 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 8.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26715 24490cab5c0f37da21c34686c2b39c05 446 Gene3D G3DSA:3.40.630.10 65 408 3.0E-118 T 12-10-2018 TL08_26715 24490cab5c0f37da21c34686c2b39c05 446 Pfam PF07687 Peptidase dimerisation domain 213 302 3.4E-8 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TL08_26715 24490cab5c0f37da21c34686c2b39c05 446 PIRSF PIRSF037226 44 440 1.5E-121 T 12-10-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted TL08_26715 24490cab5c0f37da21c34686c2b39c05 446 SUPERFAMILY SSF55031 210 320 7.2E-24 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TL08_26715 24490cab5c0f37da21c34686c2b39c05 446 SUPERFAMILY SSF53187 52 421 1.81E-53 T 12-10-2018 TL08_26715 24490cab5c0f37da21c34686c2b39c05 446 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 64 392 1.7E-70 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 TL08_26715 24490cab5c0f37da21c34686c2b39c05 446 Gene3D G3DSA:3.30.70.360 210 328 3.0E-118 T 12-10-2018 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 Gene3D G3DSA:2.40.10.10 338 461 1.1E-43 T 12-10-2018 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 SUPERFAMILY SSF50156 435 537 4.99E-16 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 SMART SM00228 464 536 1.2E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 Gene3D G3DSA:2.40.10.10 242 337 1.9E-30 T 12-10-2018 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 PRINTS PR00834 HtrA/DegQ protease family signature 412 429 1.7E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 PRINTS PR00834 HtrA/DegQ protease family signature 307 327 1.7E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 PRINTS PR00834 HtrA/DegQ protease family signature 283 295 1.7E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 PRINTS PR00834 HtrA/DegQ protease family signature 494 506 1.7E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 PRINTS PR00834 HtrA/DegQ protease family signature 348 372 1.7E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 PRINTS PR00834 HtrA/DegQ protease family signature 390 407 1.7E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 Pfam PF13180 PDZ domain 464 546 5.4E-16 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 Pfam PF13365 Trypsin-like peptidase domain 274 419 1.8E-31 T 12-10-2018 TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 SUPERFAMILY SSF50494 249 459 3.48E-55 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_03230 2e1237b14f6bf2e6e01838a4039eb75b 553 Gene3D G3DSA:2.30.42.10 462 552 1.8E-27 T 12-10-2018 TL08_22530 76b02d1b48e53448a7700d63fde4587e 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 15.995 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_22530 76b02d1b48e53448a7700d63fde4587e 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 1.1E-20 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_22530 76b02d1b48e53448a7700d63fde4587e 63 Gene3D G3DSA:2.30.170.40 19 63 1.3E-18 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_22530 76b02d1b48e53448a7700d63fde4587e 63 SUPERFAMILY SSF143800 2 62 9.22E-22 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_22530 76b02d1b48e53448a7700d63fde4587e 63 Pfam PF00830 Ribosomal L28 family 4 59 2.3E-21 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_07165 51087b583b89de0fec7500ce21465432 201 Gene3D G3DSA:3.40.50.450 1 192 5.1E-80 T 12-10-2018 TL08_07165 51087b583b89de0fec7500ce21465432 201 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 178 9.0E-61 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG TL08_07165 51087b583b89de0fec7500ce21465432 201 SUPERFAMILY SSF102405 2 178 8.85E-64 T 12-10-2018 TL08_07165 51087b583b89de0fec7500ce21465432 201 Pfam PF03641 Possible lysine decarboxylase 45 173 3.1E-43 T 12-10-2018 IPR031100 LOG family TL08_03115 2b40ccf80060da414bfd87960cf34569 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.567 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TL08_03115 2b40ccf80060da414bfd87960cf34569 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 2.9E-38 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TL08_03115 2b40ccf80060da414bfd87960cf34569 73 SUPERFAMILY SSF50249 4 72 3.94E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_03115 2b40ccf80060da414bfd87960cf34569 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 2.3E-29 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TL08_03115 2b40ccf80060da414bfd87960cf34569 73 Gene3D G3DSA:2.40.50.140 1 73 1.5E-38 T 12-10-2018 TL08_20830 5ed8385de6058f7eb2e50196c2f8f901 213 SUPERFAMILY SSF46785 131 208 9.24E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_20830 5ed8385de6058f7eb2e50196c2f8f901 213 Pfam PF13545 Crp-like helix-turn-helix domain 133 206 2.1E-10 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TL08_20830 5ed8385de6058f7eb2e50196c2f8f901 213 Gene3D G3DSA:2.60.120.10 1 129 6.1E-28 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_20830 5ed8385de6058f7eb2e50196c2f8f901 213 SMART SM00100 1 113 5.6E-10 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TL08_20830 5ed8385de6058f7eb2e50196c2f8f901 213 Pfam PF00027 Cyclic nucleotide-binding domain 14 99 4.6E-19 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TL08_20830 5ed8385de6058f7eb2e50196c2f8f901 213 SUPERFAMILY SSF51206 4 125 8.38E-27 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like TL08_20830 5ed8385de6058f7eb2e50196c2f8f901 213 Gene3D G3DSA:1.10.10.10 130 207 1.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_20830 5ed8385de6058f7eb2e50196c2f8f901 213 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 63 80 - T 12-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TL08_06030 4dfe57bf66ef67df458f2f58e5cea1af 650 SUPERFAMILY SSF56300 81 312 1.14E-19 T 12-10-2018 TL08_06030 4dfe57bf66ef67df458f2f58e5cea1af 650 SUPERFAMILY SSF49899 390 644 2.14E-22 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TL08_06030 4dfe57bf66ef67df458f2f58e5cea1af 650 Gene3D G3DSA:2.60.120.200 403 647 1.6E-17 T 12-10-2018 TL08_06030 4dfe57bf66ef67df458f2f58e5cea1af 650 Gene3D G3DSA:3.60.21.10 58 303 7.0E-11 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_06030 4dfe57bf66ef67df458f2f58e5cea1af 650 Pfam PF00149 Calcineurin-like phosphoesterase 82 245 6.3E-7 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_06030 4dfe57bf66ef67df458f2f58e5cea1af 650 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 483 643 2.9E-14 T 12-10-2018 TL08_00835 e7c8f21c2c3d9e0858d68b1bcf853c3c 160 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 60 98 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TL08_00835 e7c8f21c2c3d9e0858d68b1bcf853c3c 160 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 14 157 46.152 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 TL08_00835 e7c8f21c2c3d9e0858d68b1bcf853c3c 160 Pfam PF14437 MafB19-like deaminase 10 157 3.8E-26 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 TL08_00835 e7c8f21c2c3d9e0858d68b1bcf853c3c 160 Gene3D G3DSA:3.40.140.10 1 160 4.2E-51 T 12-10-2018 TL08_00835 e7c8f21c2c3d9e0858d68b1bcf853c3c 160 SUPERFAMILY SSF53927 4 158 2.83E-47 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TL08_19515 fadf818c919bc9d9df213d8b50bfdadf 157 SUPERFAMILY SSF69118 15 154 4.61E-38 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TL08_19515 fadf818c919bc9d9df213d8b50bfdadf 157 Gene3D G3DSA:1.20.1290.10 6 147 1.1E-41 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TL08_19515 fadf818c919bc9d9df213d8b50bfdadf 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 32 79 5.8E-15 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TL08_19515 fadf818c919bc9d9df213d8b50bfdadf 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 18 95 6.9E-18 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TL08_01455 f15637e7cb9d468db9d8407161e683c1 440 Pfam PF00437 Type II/IV secretion system protein 108 387 4.2E-69 T 12-10-2018 IPR001482 Type II/IV secretion system protein TL08_01455 f15637e7cb9d468db9d8407161e683c1 440 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 56 399 1.9E-148 T 12-10-2018 IPR022399 Helicase/secretion neighbourhood ATPase TL08_01455 f15637e7cb9d468db9d8407161e683c1 440 SUPERFAMILY SSF52540 90 393 1.6E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01455 f15637e7cb9d468db9d8407161e683c1 440 Gene3D G3DSA:3.40.50.300 208 410 6.0E-53 T 12-10-2018 TL08_01455 f15637e7cb9d468db9d8407161e683c1 440 Gene3D G3DSA:3.30.450.90 105 207 7.6E-21 T 12-10-2018 TL08_08950 9df89ba4ea03de04ec9ae63e4b70a6ea 382 Pfam PF04551 GcpE protein 21 361 1.2E-134 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TL08_08950 9df89ba4ea03de04ec9ae63e4b70a6ea 382 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.287 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TL08_08950 9df89ba4ea03de04ec9ae63e4b70a6ea 382 PIRSF PIRSF004640 12 373 2.0E-145 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TL08_08950 9df89ba4ea03de04ec9ae63e4b70a6ea 382 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 1.1E-127 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TL08_08950 9df89ba4ea03de04ec9ae63e4b70a6ea 382 SUPERFAMILY SSF56014 276 361 3.92E-12 T 12-10-2018 TL08_08950 9df89ba4ea03de04ec9ae63e4b70a6ea 382 Gene3D G3DSA:3.30.413.10 272 372 1.1E-36 T 12-10-2018 TL08_08950 9df89ba4ea03de04ec9ae63e4b70a6ea 382 SUPERFAMILY SSF51717 35 219 4.39E-9 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_08950 9df89ba4ea03de04ec9ae63e4b70a6ea 382 Gene3D G3DSA:3.20.20.20 13 271 5.7E-105 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_02645 f89f6894551fff6e739ef2182043eec5 188 Gene3D G3DSA:3.30.70.3270 26 182 7.9E-46 T 12-10-2018 TL08_02645 f89f6894551fff6e739ef2182043eec5 188 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TL08_02645 f89f6894551fff6e739ef2182043eec5 188 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TL08_02645 f89f6894551fff6e739ef2182043eec5 188 Pfam PF12838 4Fe-4S dicluster domain 52 110 5.1E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TL08_02645 f89f6894551fff6e739ef2182043eec5 188 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 9 136 2.4E-39 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02645 f89f6894551fff6e739ef2182043eec5 188 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 142 26.915 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02645 f89f6894551fff6e739ef2182043eec5 188 SUPERFAMILY SSF54862 26 153 5.44E-26 T 12-10-2018 TL08_25225 c32604986564b7f486581af616c366ae 745 Gene3D G3DSA:1.20.1250.20 315 693 2.7E-13 T 12-10-2018 TL08_25225 c32604986564b7f486581af616c366ae 745 SUPERFAMILY SSF103473 318 695 9.59E-24 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_25225 c32604986564b7f486581af616c366ae 745 Pfam PF07690 Major Facilitator Superfamily 319 662 1.4E-8 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_02355 04453cd5fb2c9ea317623e965f9fc7cb 80 Pfam PF05768 Glutaredoxin-like domain (DUF836) 6 78 7.1E-15 T 12-10-2018 IPR008554 Glutaredoxin-like TL08_02355 04453cd5fb2c9ea317623e965f9fc7cb 80 SUPERFAMILY SSF52833 2 79 1.79E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_02355 04453cd5fb2c9ea317623e965f9fc7cb 80 Gene3D G3DSA:3.40.30.10 1 79 3.4E-21 T 12-10-2018 TL08_14135 654e35dafb3f35a576461613a8bc9b35 281 Pfam PF13460 NAD(P)H-binding 7 178 1.0E-20 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_14135 654e35dafb3f35a576461613a8bc9b35 281 Gene3D G3DSA:3.40.50.720 4 276 2.7E-63 T 12-10-2018 TL08_14135 654e35dafb3f35a576461613a8bc9b35 281 SUPERFAMILY SSF51735 1 213 1.36E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 Gene3D G3DSA:3.40.50.720 235 469 2.7E-71 T 12-10-2018 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 SUPERFAMILY SSF53223 86 235 2.59E-55 T 12-10-2018 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 PIRSF PIRSF000106 20 469 1.5E-78 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 Pfam PF03949 Malic enzyme, NAD binding domain 239 458 3.2E-21 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 SUPERFAMILY SSF51735 237 465 4.09E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 SMART SM01274 92 225 2.5E-82 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 PRINTS PR00072 Malic enzyme signature 233 249 2.1E-6 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 PRINTS PR00072 Malic enzyme signature 264 280 2.1E-6 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 PRINTS PR00072 Malic enzyme signature 154 176 2.1E-6 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 Gene3D G3DSA:3.40.50.10380 79 234 8.1E-71 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 SMART SM00919 237 459 5.7E-105 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TL08_25290 ff1d2141b473cf6fe45050d6ea83928b 469 Pfam PF00390 Malic enzyme, N-terminal domain 94 225 4.0E-27 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TL08_05925 3e7809a2e51a027b81b724094abce7db 277 Gene3D G3DSA:3.40.50.150 26 185 2.7E-14 T 12-10-2018 TL08_05925 3e7809a2e51a027b81b724094abce7db 277 Pfam PF08241 Methyltransferase domain 46 125 9.4E-12 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_05925 3e7809a2e51a027b81b724094abce7db 277 SUPERFAMILY SSF53335 25 177 4.22E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_22650 832e233fef3db05e364bcd65c79bec11 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 59.522 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 2.8E-224 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 Gene3D G3DSA:3.30.499.20 4 287 7.4E-99 T 12-10-2018 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 PRINTS PR00415 Aconitase family signature 196 209 7.9E-45 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 PRINTS PR00415 Aconitase family signature 134 149 7.9E-45 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 PRINTS PR00415 Aconitase family signature 83 96 7.9E-45 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 PRINTS PR00415 Aconitase family signature 287 301 7.9E-45 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 PRINTS PR00415 Aconitase family signature 109 117 7.9E-45 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 PRINTS PR00415 Aconitase family signature 120 133 7.9E-45 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 PRINTS PR00415 Aconitase family signature 210 223 7.9E-45 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 PRINTS PR00415 Aconitase family signature 400 413 7.9E-45 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 PRINTS PR00415 Aconitase family signature 344 355 7.9E-45 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 Gene3D G3DSA:3.30.499.10 328 467 2.4E-48 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 1.2E-154 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_22650 832e233fef3db05e364bcd65c79bec11 467 SUPERFAMILY SSF53732 2 466 5.76E-160 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TL08_19670 5448c0335fc56207aabf1db8045824ae 526 PIRSF PIRSF002741 14 524 3.5E-70 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_19670 5448c0335fc56207aabf1db8045824ae 526 Gene3D G3DSA:3.10.105.10 284 490 2.5E-30 T 12-10-2018 TL08_19670 5448c0335fc56207aabf1db8045824ae 526 Gene3D G3DSA:3.40.190.10 49 283 3.0E-54 T 12-10-2018 TL08_19670 5448c0335fc56207aabf1db8045824ae 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 406 3.1E-68 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_19670 5448c0335fc56207aabf1db8045824ae 526 SUPERFAMILY SSF53850 47 513 8.32E-94 T 12-10-2018 TL08_17160 397bf5c10fa759776763134e3fa54430 267 Gene3D G3DSA:1.10.150.240 22 121 3.4E-52 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TL08_17160 397bf5c10fa759776763134e3fa54430 267 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 117 220 9.4E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_17160 397bf5c10fa759776763134e3fa54430 267 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 217 9.2E-17 T 12-10-2018 TL08_17160 397bf5c10fa759776763134e3fa54430 267 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 10 219 7.6E-49 T 12-10-2018 IPR010976 Beta-phosphoglucomutase hydrolase TL08_17160 397bf5c10fa759776763134e3fa54430 267 SUPERFAMILY SSF56784 9 247 1.18E-40 T 12-10-2018 IPR036412 HAD-like superfamily TL08_17160 397bf5c10fa759776763134e3fa54430 267 Gene3D G3DSA:3.40.50.1000 11 225 3.4E-52 T 12-10-2018 IPR023214 HAD superfamily TL08_25920 b7cc27a6053dc0d25a9ef6f5bcd9525a 262 Pfam PF11209 Protein of unknown function (DUF2993) 17 253 1.0E-41 T 12-10-2018 IPR021373 Protein of unknown function DUF2993 TL08_13340 7c9faf3a1db756347bb47c9c4958aaa5 194 SUPERFAMILY SSF55729 7 164 2.21E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_13340 7c9faf3a1db756347bb47c9c4958aaa5 194 Pfam PF13302 Acetyltransferase (GNAT) domain 13 153 3.8E-27 T 12-10-2018 IPR000182 GNAT domain TL08_13340 7c9faf3a1db756347bb47c9c4958aaa5 194 Gene3D G3DSA:3.40.630.30 4 191 4.8E-39 T 12-10-2018 TL08_15705 ab6ceb4eae18135baa484f121e60e8ea 524 Pfam PF00561 alpha/beta hydrolase fold 112 495 3.4E-44 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_15705 ab6ceb4eae18135baa484f121e60e8ea 524 SUPERFAMILY SSF53474 61 337 5.03E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_23825 803c2ed09591379efda5ba8a03a977f1 408 Gene3D G3DSA:3.40.630.10 26 367 4.7E-118 T 12-10-2018 TL08_23825 803c2ed09591379efda5ba8a03a977f1 408 Gene3D G3DSA:3.30.70.360 170 287 4.7E-118 T 12-10-2018 TL08_23825 803c2ed09591379efda5ba8a03a977f1 408 Pfam PF01546 Peptidase family M20/M25/M40 94 349 2.7E-8 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TL08_23825 803c2ed09591379efda5ba8a03a977f1 408 Pfam PF07687 Peptidase dimerisation domain 169 266 1.0E-8 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TL08_23825 803c2ed09591379efda5ba8a03a977f1 408 SUPERFAMILY SSF55031 172 278 2.22E-19 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TL08_23825 803c2ed09591379efda5ba8a03a977f1 408 SUPERFAMILY SSF53187 14 382 3.84E-57 T 12-10-2018 TL08_23825 803c2ed09591379efda5ba8a03a977f1 408 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 26 351 2.7E-57 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 TL08_23825 803c2ed09591379efda5ba8a03a977f1 408 PIRSF PIRSF037226 4 399 3.6E-136 T 12-10-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted TL08_05470 96bce6363e924876caa696d281d93543 514 Pfam PF05199 GMC oxidoreductase 364 504 3.9E-33 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 TL08_05470 96bce6363e924876caa696d281d93543 514 Gene3D G3DSA:3.30.410.40 153 446 1.0E-155 T 12-10-2018 TL08_05470 96bce6363e924876caa696d281d93543 514 Gene3D G3DSA:3.50.50.60 2 506 1.0E-155 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05470 96bce6363e924876caa696d281d93543 514 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 259 273 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TL08_05470 96bce6363e924876caa696d281d93543 514 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 85 108 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TL08_05470 96bce6363e924876caa696d281d93543 514 PIRSF PIRSF000137 350 512 7.9E-34 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TL08_05470 96bce6363e924876caa696d281d93543 514 PIRSF PIRSF000137 1 326 2.0E-74 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TL08_05470 96bce6363e924876caa696d281d93543 514 Pfam PF00732 GMC oxidoreductase 2 299 1.6E-65 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 TL08_05470 96bce6363e924876caa696d281d93543 514 SUPERFAMILY SSF54373 294 452 1.96E-9 T 12-10-2018 TL08_05470 96bce6363e924876caa696d281d93543 514 SUPERFAMILY SSF51905 1 510 6.64E-67 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_00630 b2bd7a80ece6b445fc4319901f3745e6 387 SUPERFAMILY SSF56059 3 384 8.47E-72 T 12-10-2018 TL08_00630 b2bd7a80ece6b445fc4319901f3745e6 387 SUPERFAMILY SSF52440 175 283 7.48E-33 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_00630 b2bd7a80ece6b445fc4319901f3745e6 387 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 385 1.3E-142 T 12-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain TL08_00630 b2bd7a80ece6b445fc4319901f3745e6 387 Gene3D G3DSA:3.30.1490.330 267 344 1.1E-24 T 12-10-2018 TL08_00580 5d6da75c85920654320d5ad59251225c 500 Gene3D G3DSA:3.30.70.2450 197 269 9.4E-9 T 12-10-2018 TL08_00580 5d6da75c85920654320d5ad59251225c 500 Gene3D G3DSA:3.40.30.120 399 499 3.6E-20 T 12-10-2018 TL08_00580 5d6da75c85920654320d5ad59251225c 500 Gene3D G3DSA:3.50.50.60 277 384 6.7E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_00580 5d6da75c85920654320d5ad59251225c 500 Gene3D G3DSA:3.50.50.60 1 192 3.6E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_00580 5d6da75c85920654320d5ad59251225c 500 SUPERFAMILY SSF51905 1 366 3.6E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_00580 5d6da75c85920654320d5ad59251225c 500 Pfam PF01494 FAD binding domain 2 352 4.0E-62 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_00580 5d6da75c85920654320d5ad59251225c 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 2.4E-25 T 12-10-2018 TL08_00580 5d6da75c85920654320d5ad59251225c 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 2.4E-25 T 12-10-2018 TL08_00580 5d6da75c85920654320d5ad59251225c 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.4E-25 T 12-10-2018 TL08_00580 5d6da75c85920654320d5ad59251225c 500 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 2.4E-25 T 12-10-2018 TL08_16475 f3d2982bed6bfe4baa486135fbcbb7e4 372 SUPERFAMILY SSF53474 93 341 2.4E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16475 f3d2982bed6bfe4baa486135fbcbb7e4 372 Gene3D G3DSA:3.40.50.1820 56 361 2.1E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16475 f3d2982bed6bfe4baa486135fbcbb7e4 372 Pfam PF00756 Putative esterase 96 322 4.1E-29 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TL08_19410 403bed7e59c4b56974786548aa6513a0 347 Gene3D G3DSA:3.30.470.30 52 175 1.4E-48 T 12-10-2018 TL08_19410 403bed7e59c4b56974786548aa6513a0 347 Gene3D G3DSA:3.30.1490.70 39 218 1.4E-48 T 12-10-2018 TL08_19410 403bed7e59c4b56974786548aa6513a0 347 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 37 342 1.5E-79 T 12-10-2018 IPR014146 DNA ligase D, ligase domain TL08_19410 403bed7e59c4b56974786548aa6513a0 347 Pfam PF01068 ATP dependent DNA ligase domain 41 219 1.7E-31 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 TL08_19410 403bed7e59c4b56974786548aa6513a0 347 SUPERFAMILY SSF50249 223 342 3.08E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_19410 403bed7e59c4b56974786548aa6513a0 347 Gene3D G3DSA:2.40.50.140 222 343 2.4E-39 T 12-10-2018 TL08_19410 403bed7e59c4b56974786548aa6513a0 347 SUPERFAMILY SSF56091 25 219 4.03E-42 T 12-10-2018 TL08_19410 403bed7e59c4b56974786548aa6513a0 347 Pfam PF04679 ATP dependent DNA ligase C terminal region 240 336 5.3E-24 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 TL08_14130 b3a7bb9401d29eadd3dc6f28b57ae6bb 177 Gene3D G3DSA:3.10.129.10 25 147 1.3E-20 T 12-10-2018 TL08_14130 b3a7bb9401d29eadd3dc6f28b57ae6bb 177 SUPERFAMILY SSF54637 28 165 2.16E-26 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_14130 b3a7bb9401d29eadd3dc6f28b57ae6bb 177 Pfam PF13279 Thioesterase-like superfamily 32 163 5.3E-18 T 12-10-2018 TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 Pfam PF00005 ABC transporter 20 155 3.5E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 Pfam PF00005 ABC transporter 303 436 2.2E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 SMART SM00382 311 480 1.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 SMART SM00382 29 207 1.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 SUPERFAMILY SSF52540 270 483 1.43E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 Gene3D G3DSA:3.40.50.300 266 513 1.8E-60 T 12-10-2018 TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 Gene3D G3DSA:3.40.50.300 2 235 5.9E-59 T 12-10-2018 TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 SUPERFAMILY SSF52540 5 203 6.9E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_03655 318e359bc2d450c00e4a8b7cfb8c17fb 599 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_00945 684714fb302eae22be4a1d6fe0d29b93 386 Pfam PF13378 Enolase C-terminal domain-like 153 373 9.4E-39 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_00945 684714fb302eae22be4a1d6fe0d29b93 386 Gene3D G3DSA:3.30.390.10 1 114 3.5E-18 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_00945 684714fb302eae22be4a1d6fe0d29b93 386 SUPERFAMILY SSF54826 21 123 7.07E-16 T 12-10-2018 TL08_00945 684714fb302eae22be4a1d6fe0d29b93 386 SUPERFAMILY SSF51604 123 382 7.66E-48 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_00945 684714fb302eae22be4a1d6fe0d29b93 386 Gene3D G3DSA:3.20.20.120 118 381 2.1E-59 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_00945 684714fb302eae22be4a1d6fe0d29b93 386 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 35 123 1.2E-7 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TL08_00945 684714fb302eae22be4a1d6fe0d29b93 386 SMART SM00922 147 248 1.8E-13 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_00220 e8d2672488b57af928a193367af87dab 304 Gene3D G3DSA:1.10.510.10 162 249 3.9E-8 T 12-10-2018 TL08_00220 e8d2672488b57af928a193367af87dab 304 Pfam PF01636 Phosphotransferase enzyme family 45 243 5.5E-18 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_00220 e8d2672488b57af928a193367af87dab 304 SUPERFAMILY SSF56112 22 269 2.93E-30 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 246 1.4E-58 T 12-10-2018 TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.4E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.4E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.4E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.4E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.4E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 SUPERFAMILY SSF51735 1 248 4.26E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 8.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 8.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 8.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_24265 5fc3db7a4bbec77851acd488fd69d1ea 259 Gene3D G3DSA:3.40.50.720 1 248 2.7E-74 T 12-10-2018 TL08_21895 0a0c863b850a9bcf7ba96b9096755a87 333 SUPERFAMILY SSF102114 35 296 6.93E-61 T 12-10-2018 TL08_21895 0a0c863b850a9bcf7ba96b9096755a87 333 Pfam PF04055 Radical SAM superfamily 81 235 9.5E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_21895 0a0c863b850a9bcf7ba96b9096755a87 333 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 2.3E-7 T 12-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TL08_21895 0a0c863b850a9bcf7ba96b9096755a87 333 PIRSF PIRSF005963 5 319 2.4E-119 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TL08_21895 0a0c863b850a9bcf7ba96b9096755a87 333 SMART SM00729 71 277 8.9E-15 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_21895 0a0c863b850a9bcf7ba96b9096755a87 333 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 137.789 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TL08_21895 0a0c863b850a9bcf7ba96b9096755a87 333 TIGRFAM TIGR00510 lipA: lipoyl synthase 17 303 1.4E-96 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TL08_21895 0a0c863b850a9bcf7ba96b9096755a87 333 Gene3D G3DSA:3.20.20.70 73 277 5.0E-18 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 SMART SM00436 112 200 9.2E-44 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 771 54.04 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Gene3D G3DSA:2.70.20.10 192 488 5.1E-171 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Pfam PF01751 Toprim domain 1 121 3.6E-28 T 12-10-2018 IPR006171 TOPRIM domain TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Pfam PF13368 Topoisomerase C-terminal repeat 750 803 2.8E-17 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Pfam PF13368 Topoisomerase C-terminal repeat 817 868 2.4E-20 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Pfam PF13368 Topoisomerase C-terminal repeat 625 681 1.1E-6 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Pfam PF13368 Topoisomerase C-terminal repeat 688 746 2.4E-13 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 SMART SM00437 271 541 8.1E-123 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Gene3D G3DSA:1.10.460.10 143 581 5.1E-171 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 SUPERFAMILY SSF56712 1 582 1.19E-174 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 308 322 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Gene3D G3DSA:3.40.50.140 1 142 9.3E-57 T 12-10-2018 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Pfam PF01131 DNA topoisomerase 136 578 1.2E-118 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 392 408 3.7E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 170 188 3.7E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 313 322 3.7E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 86 99 3.7E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 504 518 3.7E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 SMART SM00493 1 112 7.5E-36 T 12-10-2018 IPR006171 TOPRIM domain TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 Gene3D G3DSA:1.10.290.10 279 407 5.1E-171 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TL08_01505 ca12d45a5b11ddd76619bab28bfb6eff 920 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 1 648 8.2E-247 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 TL08_11190 e3c0ae82a4019e838690864eee43ae78 302 Gene3D G3DSA:3.20.20.140 4 300 1.3E-84 T 12-10-2018 TL08_11190 e3c0ae82a4019e838690864eee43ae78 302 SUPERFAMILY SSF51556 5 299 1.41E-61 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_11190 e3c0ae82a4019e838690864eee43ae78 302 Pfam PF04909 Amidohydrolase 7 299 5.0E-45 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 2.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 2.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 2.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 464 2.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 SMART SM00387 358 467 2.8E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_05535 de1ff75667be008d0fa595d39693ee00 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 465 2.1E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_05535 de1ff75667be008d0fa595d39693ee00 470 Gene3D G3DSA:3.30.565.10 323 469 8.2E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_05535 de1ff75667be008d0fa595d39693ee00 470 SUPERFAMILY SSF55874 307 465 2.1E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_05535 de1ff75667be008d0fa595d39693ee00 470 SMART SM00304 191 243 1.9E-14 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 SUPERFAMILY SSF158472 191 240 6.15E-9 T 12-10-2018 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 318 1.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 Gene3D G3DSA:1.20.1480.50 152 244 5.5E-11 T 12-10-2018 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 SMART SM00388 251 318 4.3E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 SUPERFAMILY SSF47384 234 318 5.3E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 Pfam PF00672 HAMP domain 191 239 3.4E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_05535 de1ff75667be008d0fa595d39693ee00 470 Gene3D G3DSA:1.10.287.130 245 322 9.4E-17 T 12-10-2018 TL08_13450 d4a0c5601691eef352aee479cff85984 275 Gene3D G3DSA:1.10.3720.10 2 262 1.8E-53 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13450 d4a0c5601691eef352aee479cff85984 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 268 9.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_13450 d4a0c5601691eef352aee479cff85984 275 SUPERFAMILY SSF161098 3 274 5.63E-65 T 12-10-2018 IPR035906 MetI-like superfamily TL08_11275 3d9e86c63a51c4f817de7990e1b87d38 345 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 221 1.1E-42 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal TL08_11275 3d9e86c63a51c4f817de7990e1b87d38 345 Pfam PF00553 Cellulose binding domain 244 344 1.5E-27 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TL08_11275 3d9e86c63a51c4f817de7990e1b87d38 345 SUPERFAMILY SSF81296 32 224 1.05E-45 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_11275 3d9e86c63a51c4f817de7990e1b87d38 345 SMART SM00637 244 344 2.8E-36 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TL08_11275 3d9e86c63a51c4f817de7990e1b87d38 345 Gene3D G3DSA:2.70.50.50 32 226 1.1E-67 T 12-10-2018 TL08_11275 3d9e86c63a51c4f817de7990e1b87d38 345 SUPERFAMILY SSF49384 243 344 1.33E-30 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 TL08_11275 3d9e86c63a51c4f817de7990e1b87d38 345 Gene3D G3DSA:2.60.40.290 240 345 4.7E-31 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 Pfam PF00106 short chain dehydrogenase 98 283 5.1E-55 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 116 5.7E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 263 280 5.7E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 179 5.7E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 299 319 5.7E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 232 5.7E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 242 261 5.7E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 242 261 1.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 222 230 1.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 179 1.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 Gene3D G3DSA:3.40.50.720 85 338 7.4E-71 T 12-10-2018 TL08_17415 6f08f215ebeae4f23d3082a2a5c1a2b3 338 SUPERFAMILY SSF51735 94 336 2.59E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15580 8648d4b5d85bb9207c7d0537ac819eb4 619 SUPERFAMILY SSF56112 12 266 5.53E-62 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_15580 8648d4b5d85bb9207c7d0537ac819eb4 619 Pfam PF00069 Protein kinase domain 17 264 3.0E-38 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_15580 8648d4b5d85bb9207c7d0537ac819eb4 619 Gene3D G3DSA:1.10.510.10 95 280 2.3E-47 T 12-10-2018 TL08_15580 8648d4b5d85bb9207c7d0537ac819eb4 619 SMART SM00220 15 264 4.8E-40 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_15580 8648d4b5d85bb9207c7d0537ac819eb4 619 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_15580 8648d4b5d85bb9207c7d0537ac819eb4 619 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_15580 8648d4b5d85bb9207c7d0537ac819eb4 619 Gene3D G3DSA:3.30.200.20 5 93 3.4E-16 T 12-10-2018 TL08_10285 a060ceed101228c3b4d643f75906824f 130 Gene3D G3DSA:3.10.180.10 1 115 9.9E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_10285 a060ceed101228c3b4d643f75906824f 130 SUPERFAMILY SSF54593 1 109 2.72E-5 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 SMART SM00245 883 1076 3.8E-19 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 Gene3D G3DSA:3.90.226.10 897 1110 7.2E-62 T 12-10-2018 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 SUPERFAMILY SSF69304 15 293 1.7E-30 T 12-10-2018 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 SUPERFAMILY SSF69304 397 660 5.89E-18 T 12-10-2018 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 Gene3D G3DSA:2.120.10.60 2 291 1.9E-87 T 12-10-2018 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 Pfam PF14685 Tricorn protease PDZ domain 777 856 3.9E-26 T 12-10-2018 IPR029414 Tricorn protease, PDZ domain TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 Gene3D G3DSA:3.30.750.44 697 765 3.0E-25 T 12-10-2018 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 PIRSF PIRSF036421 3 1109 0.0 T 12-10-2018 IPR012393 Tricorn protease GO:0008236 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 Pfam PF07676 WD40-like Beta Propeller Repeat 53 67 0.0092 T 12-10-2018 IPR011659 WD40-like Beta Propeller TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 Gene3D G3DSA:2.130.10.10 315 677 1.6E-90 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 SUPERFAMILY SSF50156 777 853 6.3E-9 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 Pfam PF14684 Tricorn protease C1 domain 698 763 1.3E-25 T 12-10-2018 IPR028204 Tricorn protease C1 domain TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 Pfam PF03572 Peptidase family S41 919 1075 1.6E-20 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TL08_03745 3d7df90ccc9073c69e0310dd13b9b88c 1117 SUPERFAMILY SSF52096 695 1100 1.18E-63 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_13830 5aa45390fe6056f4b3ece9b63b3e9853 149 SUPERFAMILY SSF50475 10 140 3.55E-22 T 12-10-2018 TL08_13830 5aa45390fe6056f4b3ece9b63b3e9853 149 Gene3D G3DSA:2.30.110.10 7 133 1.6E-18 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_13830 5aa45390fe6056f4b3ece9b63b3e9853 149 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 96 9.4E-13 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_13830 5aa45390fe6056f4b3ece9b63b3e9853 149 TIGRFAM TIGR04023 PPOX_MSMEG_5819: PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family 4 131 2.8E-33 T 12-10-2018 IPR024031 PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family KEGG: 00253+1.3.98.4|MetaCyc: PWY-7812 TL08_11230 57795bdfe522ae75904385be20770543 429 Pfam PF02817 e3 binding domain 129 162 5.9E-14 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TL08_11230 57795bdfe522ae75904385be20770543 429 SUPERFAMILY SSF51230 2 94 8.11E-27 T 12-10-2018 IPR011053 Single hybrid motif TL08_11230 57795bdfe522ae75904385be20770543 429 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 198 428 1.5E-80 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TL08_11230 57795bdfe522ae75904385be20770543 429 Gene3D G3DSA:3.30.559.10 183 426 1.1E-92 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_11230 57795bdfe522ae75904385be20770543 429 SUPERFAMILY SSF52777 198 427 3.07E-79 T 12-10-2018 TL08_11230 57795bdfe522ae75904385be20770543 429 Gene3D G3DSA:4.10.320.10 123 178 2.6E-17 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TL08_11230 57795bdfe522ae75904385be20770543 429 Pfam PF00364 Biotin-requiring enzyme 3 73 1.6E-20 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TL08_11230 57795bdfe522ae75904385be20770543 429 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 3 428 7.4E-134 T 12-10-2018 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 TL08_11230 57795bdfe522ae75904385be20770543 429 Gene3D G3DSA:2.40.50.100 1 101 3.2E-30 T 12-10-2018 TL08_11230 57795bdfe522ae75904385be20770543 429 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TL08_11230 57795bdfe522ae75904385be20770543 429 SUPERFAMILY SSF47005 124 166 1.7E-11 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TL08_13320 e01d48968f191acdcb14043f8944fda7 154 SUPERFAMILY SSF46785 7 146 6.84E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_13320 e01d48968f191acdcb14043f8944fda7 154 SMART SM00347 33 136 9.2E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13320 e01d48968f191acdcb14043f8944fda7 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 6.1E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13320 e01d48968f191acdcb14043f8944fda7 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 6.1E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13320 e01d48968f191acdcb14043f8944fda7 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 6.1E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13320 e01d48968f191acdcb14043f8944fda7 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 6.1E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13320 e01d48968f191acdcb14043f8944fda7 154 Pfam PF12802 MarR family 40 99 1.6E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13320 e01d48968f191acdcb14043f8944fda7 154 Gene3D G3DSA:1.10.10.10 7 148 1.1E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03505 da2a7ecc5e379bcd1f9f0019101d57e7 434 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 152 424 5.7E-99 T 12-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 TL08_03505 da2a7ecc5e379bcd1f9f0019101d57e7 434 Gene3D G3DSA:3.60.120.10 87 431 2.1E-103 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TL08_03505 da2a7ecc5e379bcd1f9f0019101d57e7 434 Pfam PF00425 chorismate binding enzyme 165 420 3.1E-77 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TL08_03505 da2a7ecc5e379bcd1f9f0019101d57e7 434 SUPERFAMILY SSF56322 90 429 2.09E-93 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TL08_03505 da2a7ecc5e379bcd1f9f0019101d57e7 434 PRINTS PR00095 Anthranilate synthase component I signature 278 291 1.5E-8 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_03505 da2a7ecc5e379bcd1f9f0019101d57e7 434 PRINTS PR00095 Anthranilate synthase component I signature 358 372 1.5E-8 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_03505 da2a7ecc5e379bcd1f9f0019101d57e7 434 PRINTS PR00095 Anthranilate synthase component I signature 373 387 1.5E-8 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_03505 da2a7ecc5e379bcd1f9f0019101d57e7 434 PRINTS PR00095 Anthranilate synthase component I signature 264 277 1.5E-8 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_09780 9fec8d49b076df5543bdb15148de3fe8 270 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 258 32.305 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TL08_09780 9fec8d49b076df5543bdb15148de3fe8 270 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 52 69 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 TL08_09780 9fec8d49b076df5543bdb15148de3fe8 270 SUPERFAMILY SSF51366 13 258 1.98E-76 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TL08_09780 9fec8d49b076df5543bdb15148de3fe8 270 Gene3D G3DSA:3.20.20.70 1 270 4.2E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_09780 9fec8d49b076df5543bdb15148de3fe8 270 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 256 1.5E-76 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TL08_03545 67eb9913bb273631e6250c8a23a0c424 271 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 7 265 4.5E-75 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TL08_03545 67eb9913bb273631e6250c8a23a0c424 271 Pfam PF00398 Ribosomal RNA adenine dimethylase 11 262 1.3E-43 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TL08_03545 67eb9913bb273631e6250c8a23a0c424 271 SMART SM00650 23 197 8.2E-65 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TL08_03545 67eb9913bb273631e6250c8a23a0c424 271 Gene3D G3DSA:1.10.8.100 205 269 3.7E-19 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 TL08_03545 67eb9913bb273631e6250c8a23a0c424 271 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 7 268 48.636 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TL08_03545 67eb9913bb273631e6250c8a23a0c424 271 Gene3D G3DSA:3.40.50.150 1 200 6.3E-58 T 12-10-2018 TL08_03545 67eb9913bb273631e6250c8a23a0c424 271 SUPERFAMILY SSF53335 7 265 2.74E-64 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_03545 67eb9913bb273631e6250c8a23a0c424 271 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 39 66 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TL08_02145 ee4489d4600b05f25b3a3148cfdbc0de 515 SUPERFAMILY SSF51445 15 336 4.95E-72 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_02145 ee4489d4600b05f25b3a3148cfdbc0de 515 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 35 337 7.1E-69 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_02145 ee4489d4600b05f25b3a3148cfdbc0de 515 PRINTS PR00133 Glycosyl hydrolase family 3 signature 88 107 3.6E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_02145 ee4489d4600b05f25b3a3148cfdbc0de 515 PRINTS PR00133 Glycosyl hydrolase family 3 signature 166 182 3.6E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_02145 ee4489d4600b05f25b3a3148cfdbc0de 515 PRINTS PR00133 Glycosyl hydrolase family 3 signature 241 259 3.6E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_02145 ee4489d4600b05f25b3a3148cfdbc0de 515 Gene3D G3DSA:3.20.20.300 4 338 6.4E-94 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 TL08_02230 fdc0d0208c8155dc801948fcd1e788d0 371 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 229 367 2.1E-36 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_02230 fdc0d0208c8155dc801948fcd1e788d0 371 SUPERFAMILY SSF56194 227 369 1.2E-29 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_02230 fdc0d0208c8155dc801948fcd1e788d0 371 Pfam PF01565 FAD binding domain 40 169 5.6E-21 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TL08_02230 fdc0d0208c8155dc801948fcd1e788d0 371 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 371 74.433 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_02230 fdc0d0208c8155dc801948fcd1e788d0 371 Gene3D G3DSA:3.30.465.10 89 241 1.9E-38 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TL08_02230 fdc0d0208c8155dc801948fcd1e788d0 371 Gene3D G3DSA:3.90.78.10 247 370 4.2E-34 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_02230 fdc0d0208c8155dc801948fcd1e788d0 371 SUPERFAMILY SSF56176 23 206 2.52E-35 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_02230 fdc0d0208c8155dc801948fcd1e788d0 371 Gene3D G3DSA:3.30.43.10 13 88 6.6E-21 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TL08_17100 6032433598048b9a23d1a1160a12516e 460 SUPERFAMILY SSF48264 11 404 1.57E-59 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17100 6032433598048b9a23d1a1160a12516e 460 PRINTS PR00359 B-class P450 signature 106 117 2.7E-16 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17100 6032433598048b9a23d1a1160a12516e 460 PRINTS PR00359 B-class P450 signature 298 325 2.7E-16 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17100 6032433598048b9a23d1a1160a12516e 460 PRINTS PR00359 B-class P450 signature 152 168 2.7E-16 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17100 6032433598048b9a23d1a1160a12516e 460 PRINTS PR00359 B-class P450 signature 202 224 2.7E-16 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17100 6032433598048b9a23d1a1160a12516e 460 PRINTS PR00359 B-class P450 signature 169 184 2.7E-16 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17100 6032433598048b9a23d1a1160a12516e 460 Gene3D G3DSA:1.10.630.10 18 409 1.0E-87 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16155 50585d50878d59fc6bcc9b3643f9d6a2 472 Gene3D G3DSA:3.30.70.2190 219 341 3.9E-35 T 12-10-2018 TL08_16155 50585d50878d59fc6bcc9b3643f9d6a2 472 Gene3D G3DSA:3.30.43.10 1 94 3.8E-25 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TL08_16155 50585d50878d59fc6bcc9b3643f9d6a2 472 SUPERFAMILY SSF55103 221 471 9.81E-56 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TL08_16155 50585d50878d59fc6bcc9b3643f9d6a2 472 Gene3D G3DSA:3.30.465.10 96 217 3.1E-46 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TL08_16155 50585d50878d59fc6bcc9b3643f9d6a2 472 SUPERFAMILY SSF56176 4 216 1.23E-73 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_16155 50585d50878d59fc6bcc9b3643f9d6a2 472 Gene3D G3DSA:3.30.70.2740 342 428 3.1E-28 T 12-10-2018 TL08_16155 50585d50878d59fc6bcc9b3643f9d6a2 472 Pfam PF01565 FAD binding domain 41 178 1.0E-33 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TL08_16155 50585d50878d59fc6bcc9b3643f9d6a2 472 Gene3D G3DSA:1.10.45.10 429 469 9.8E-17 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TL08_16155 50585d50878d59fc6bcc9b3643f9d6a2 472 Pfam PF02913 FAD linked oxidases, C-terminal domain 220 468 2.3E-49 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TL08_11280 3dcd674b6488d916484429d50004a427 169 SMART SM00347 32 135 4.7E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_11280 3dcd674b6488d916484429d50004a427 169 SUPERFAMILY SSF46785 5 148 6.92E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_11280 3dcd674b6488d916484429d50004a427 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 3.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_11280 3dcd674b6488d916484429d50004a427 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 3.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_11280 3dcd674b6488d916484429d50004a427 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 3.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_11280 3dcd674b6488d916484429d50004a427 169 Gene3D G3DSA:1.10.10.10 6 156 1.5E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11280 3dcd674b6488d916484429d50004a427 169 Pfam PF01047 MarR family 53 97 5.0E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_15075 83cb532f5ff24508c996d352c6684371 290 Pfam PF00561 alpha/beta hydrolase fold 28 143 1.1E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_15075 83cb532f5ff24508c996d352c6684371 290 SUPERFAMILY SSF53474 3 289 8.26E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15075 83cb532f5ff24508c996d352c6684371 290 Gene3D G3DSA:3.40.50.1820 1 290 1.2E-73 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15075 83cb532f5ff24508c996d352c6684371 290 PRINTS PR00412 Epoxide hydrolase signature 115 128 1.1E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_15075 83cb532f5ff24508c996d352c6684371 290 PRINTS PR00412 Epoxide hydrolase signature 101 114 1.1E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_15075 83cb532f5ff24508c996d352c6684371 290 PRINTS PR00412 Epoxide hydrolase signature 34 52 1.1E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_15075 83cb532f5ff24508c996d352c6684371 290 PRINTS PR00412 Epoxide hydrolase signature 265 287 1.1E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_08125 b6687b38397c23643f6eba1596f1aa1e 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 45 66 1.3E-12 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_08125 b6687b38397c23643f6eba1596f1aa1e 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 160 184 1.3E-12 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_08125 b6687b38397c23643f6eba1596f1aa1e 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 218 237 1.3E-12 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_08125 b6687b38397c23643f6eba1596f1aa1e 277 PRINTS PR00164 ABC-2 type transport system membrane protein signature 198 217 1.3E-12 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_08125 b6687b38397c23643f6eba1596f1aa1e 277 Pfam PF01061 ABC-2 type transporter 26 239 1.5E-16 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_08125 b6687b38397c23643f6eba1596f1aa1e 277 PIRSF PIRSF006648 1 276 5.8E-24 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_17645 ab23e03c6afda73837c0b0c191eb130e 466 Gene3D G3DSA:3.60.40.10 227 447 4.0E-54 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_17645 ab23e03c6afda73837c0b0c191eb130e 466 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 263 446 2.3E-40 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_17645 ab23e03c6afda73837c0b0c191eb130e 466 SUPERFAMILY SSF81606 249 444 2.62E-8 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_17645 ab23e03c6afda73837c0b0c191eb130e 466 SMART SM00331 232 446 1.8E-30 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_01530 113dc2b683f338e1d403164f08b00150 432 Pfam PF00589 Phage integrase family 204 414 7.1E-24 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_01530 113dc2b683f338e1d403164f08b00150 432 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 74 126 6.5E-5 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TL08_01530 113dc2b683f338e1d403164f08b00150 432 SUPERFAMILY SSF56349 73 422 2.65E-58 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_01530 113dc2b683f338e1d403164f08b00150 432 Gene3D G3DSA:1.10.150.130 70 178 1.7E-24 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_26440 2b1d425c1fa5f78789f67ce81905d753 768 SUPERFAMILY SSF46548 281 423 8.89E-21 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TL08_26440 2b1d425c1fa5f78789f67ce81905d753 768 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 395 406 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TL08_26440 2b1d425c1fa5f78789f67ce81905d753 768 Pfam PF13183 4Fe-4S dicluster domain 296 409 1.9E-13 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TL08_26440 2b1d425c1fa5f78789f67ce81905d753 768 Pfam PF02754 Cysteine-rich domain 608 694 1.9E-16 T 12-10-2018 IPR004017 Cysteine-rich domain TL08_26440 2b1d425c1fa5f78789f67ce81905d753 768 Pfam PF02754 Cysteine-rich domain 478 569 1.4E-14 T 12-10-2018 IPR004017 Cysteine-rich domain TL08_09880 3c720e73916b4076b56871708d11e3cb 308 SUPERFAMILY SSF48576 22 301 5.76E-70 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_09880 3c720e73916b4076b56871708d11e3cb 308 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 170 195 - T 12-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TL08_09880 3c720e73916b4076b56871708d11e3cb 308 Gene3D G3DSA:1.10.600.10 9 299 8.1E-85 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_09880 3c720e73916b4076b56871708d11e3cb 308 Pfam PF00494 Squalene/phytoene synthase 30 287 5.3E-63 T 12-10-2018 TL08_19350 58ae56ae4050af7ae5d4b13305e99f49 252 Gene3D G3DSA:1.10.1660.10 122 240 6.0E-20 T 12-10-2018 TL08_19350 58ae56ae4050af7ae5d4b13305e99f49 252 Gene3D G3DSA:1.10.1660.10 12 121 7.5E-11 T 12-10-2018 TL08_19350 58ae56ae4050af7ae5d4b13305e99f49 252 SMART SM00422 8 76 0.0015 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_19350 58ae56ae4050af7ae5d4b13305e99f49 252 SMART SM00422 127 196 1.5E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_19350 58ae56ae4050af7ae5d4b13305e99f49 252 SUPERFAMILY SSF46955 127 239 2.88E-18 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_19350 58ae56ae4050af7ae5d4b13305e99f49 252 SUPERFAMILY SSF46955 12 114 3.07E-11 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_19350 58ae56ae4050af7ae5d4b13305e99f49 252 Pfam PF13411 MerR HTH family regulatory protein 12 73 7.1E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_19350 58ae56ae4050af7ae5d4b13305e99f49 252 Pfam PF13411 MerR HTH family regulatory protein 128 194 4.0E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_04795 445a4029eaab50b7137bcc1a6e5e4589 389 Gene3D G3DSA:3.40.50.720 16 262 2.0E-86 T 12-10-2018 TL08_04795 445a4029eaab50b7137bcc1a6e5e4589 389 Pfam PF00899 ThiF family 24 255 5.3E-62 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TL08_04795 445a4029eaab50b7137bcc1a6e5e4589 389 SUPERFAMILY SSF69572 10 356 7.72E-98 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TL08_04795 445a4029eaab50b7137bcc1a6e5e4589 389 Gene3D G3DSA:3.40.250.10 283 382 1.4E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_04795 445a4029eaab50b7137bcc1a6e5e4589 389 SMART SM00450 287 384 2.7E-28 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_04795 445a4029eaab50b7137bcc1a6e5e4589 389 Pfam PF00581 Rhodanese-like domain 287 380 3.2E-13 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_10115 8759c07ee86eea7e2558d78c167c9237 379 SUPERFAMILY SSF48452 159 359 1.5E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_16200 c7478062ca578f21d92a830299358ef6 683 SUPERFAMILY SSF52540 174 300 2.55E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17665 305e028a3be7688cc3ebb67ecba606f5 297 SUPERFAMILY SSF161098 32 297 2.43E-62 T 12-10-2018 IPR035906 MetI-like superfamily TL08_17665 305e028a3be7688cc3ebb67ecba606f5 297 Gene3D G3DSA:1.10.3720.10 30 288 1.1E-53 T 12-10-2018 IPR035906 MetI-like superfamily TL08_17665 305e028a3be7688cc3ebb67ecba606f5 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 286 1.3E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 Pfam PF16124 RecQ zinc-binding 345 406 6.9E-17 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 SMART SM00341 542 613 6.4E-12 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 Gene3D G3DSA:1.10.10.10 343 530 1.9E-46 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 17 468 3.9E-149 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 Pfam PF00271 Helicase conserved C-terminal domain 226 332 1.2E-15 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 Pfam PF00270 DEAD/DEAH box helicase 30 187 1.6E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 Pfam PF09382 RQC domain 408 522 1.9E-34 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 SMART SM00487 23 217 5.0E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 SUPERFAMILY SSF52540 14 198 2.66E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 Gene3D G3DSA:1.10.150.80 546 614 1.1E-23 T 12-10-2018 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 SMART SM00490 252 333 4.9E-23 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 SUPERFAMILY SSF47819 543 613 2.09E-21 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 17 611 1.0E-229 T 12-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 Gene3D G3DSA:3.40.50.300 6 209 2.6E-77 T 12-10-2018 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 Pfam PF00570 HRDC domain 548 611 2.3E-23 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 SMART SM00956 413 519 1.0E-44 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 Gene3D G3DSA:3.40.50.300 210 342 1.2E-38 T 12-10-2018 TL08_10090 4937ff6e500ae1bfc3350d723f35e1ea 614 SUPERFAMILY SSF52540 209 460 4.71E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18805 372dfc5cfcb89f2d84060e77d05ee643 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18805 372dfc5cfcb89f2d84060e77d05ee643 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18805 372dfc5cfcb89f2d84060e77d05ee643 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 2.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18805 372dfc5cfcb89f2d84060e77d05ee643 197 Gene3D G3DSA:1.10.357.10 12 196 2.0E-47 T 12-10-2018 TL08_18805 372dfc5cfcb89f2d84060e77d05ee643 197 SUPERFAMILY SSF46689 5 78 8.72E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18805 372dfc5cfcb89f2d84060e77d05ee643 197 SUPERFAMILY SSF48498 81 193 2.22E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_08485 350a7ce8a765cf188e10756d0bcb8288 192 Hamap MF_01114 Regulatory protein RecX [recX]. 12 180 15.994 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 TL08_08485 350a7ce8a765cf188e10756d0bcb8288 192 Pfam PF02631 RecX family 56 175 2.7E-29 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 TL08_08485 350a7ce8a765cf188e10756d0bcb8288 192 Gene3D G3DSA:1.10.10.10 79 124 7.9E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08485 350a7ce8a765cf188e10756d0bcb8288 192 Gene3D G3DSA:1.10.10.2800 12 78 5.5E-7 T 12-10-2018 TL08_25940 2c73c22119804016bc20c8f7c8d44dbd 103 SUPERFAMILY SSF49478 25 82 9.42E-7 T 12-10-2018 TL08_25940 2c73c22119804016bc20c8f7c8d44dbd 103 Pfam PF07210 Protein of unknown function (DUF1416) 4 100 7.3E-34 T 12-10-2018 IPR010814 Protein of unknown function DUF1416 TL08_14045 f442e204f69ece222854d2a5f9866f62 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 74 2.4E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14045 f442e204f69ece222854d2a5f9866f62 224 SUPERFAMILY SSF48498 93 197 9.89E-16 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_14045 f442e204f69ece222854d2a5f9866f62 224 SUPERFAMILY SSF46689 16 96 1.05E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14045 f442e204f69ece222854d2a5f9866f62 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14045 f442e204f69ece222854d2a5f9866f62 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 1.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14045 f442e204f69ece222854d2a5f9866f62 224 Gene3D G3DSA:1.10.357.10 11 204 2.8E-49 T 12-10-2018 TL08_07045 a84999712df37f179159a231f824d8c1 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 294 4.8E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_07045 a84999712df37f179159a231f824d8c1 305 Gene3D G3DSA:1.10.3720.10 31 295 4.8E-59 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07045 a84999712df37f179159a231f824d8c1 305 SUPERFAMILY SSF161098 34 305 5.23E-66 T 12-10-2018 IPR035906 MetI-like superfamily TL08_22745 a912f3ce88a4c057ab7ce7a73ab653b6 614 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 611 44.344 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_22745 a912f3ce88a4c057ab7ce7a73ab653b6 614 Gene3D G3DSA:3.50.30.80 423 574 2.8E-54 T 12-10-2018 TL08_22745 a912f3ce88a4c057ab7ce7a73ab653b6 614 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 611 3.2E-232 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_22745 a912f3ce88a4c057ab7ce7a73ab653b6 614 Pfam PF00920 Dehydratase family 34 608 1.9E-210 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_22745 a912f3ce88a4c057ab7ce7a73ab653b6 614 SUPERFAMILY SSF52016 423 612 7.69E-58 T 12-10-2018 TL08_22745 a912f3ce88a4c057ab7ce7a73ab653b6 614 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_22745 a912f3ce88a4c057ab7ce7a73ab653b6 614 SUPERFAMILY SSF143975 4 422 2.35E-131 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_22745 a912f3ce88a4c057ab7ce7a73ab653b6 614 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_02340 ba8b984995397dd9f9c4a2e56a81e058 301 SUPERFAMILY SSF56784 49 266 4.88E-29 T 12-10-2018 IPR036412 HAD-like superfamily TL08_02340 ba8b984995397dd9f9c4a2e56a81e058 301 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 49 249 3.2E-55 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like TL08_02340 ba8b984995397dd9f9c4a2e56a81e058 301 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 49 237 4.6E-17 T 12-10-2018 TL08_02340 ba8b984995397dd9f9c4a2e56a81e058 301 Pfam PF12710 haloacid dehalogenase-like hydrolase 50 236 2.6E-26 T 12-10-2018 TL08_02340 ba8b984995397dd9f9c4a2e56a81e058 301 Gene3D G3DSA:1.20.1440.100 61 137 4.4E-62 T 12-10-2018 TL08_02340 ba8b984995397dd9f9c4a2e56a81e058 301 Gene3D G3DSA:3.40.50.1000 50 262 4.4E-62 T 12-10-2018 IPR023214 HAD superfamily TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 Pfam PF00686 Starch binding domain 522 605 7.4E-27 T 12-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 SUPERFAMILY SSF51011 420 508 3.66E-31 T 12-10-2018 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 SMART SM00632 423 509 7.9E-43 T 12-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 SMART SM00642 77 414 2.1E-74 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 Gene3D G3DSA:2.60.40.10 510 614 8.5E-31 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 SMART SM01065 518 610 1.9E-27 T 12-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 Gene3D G3DSA:3.20.20.80 76 419 3.0E-136 T 12-10-2018 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 SUPERFAMILY SSF49452 522 613 1.47E-30 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 Gene3D G3DSA:2.60.40.1180 420 509 1.1E-32 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 SUPERFAMILY SSF51445 75 416 1.82E-77 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 Pfam PF00128 Alpha amylase, catalytic domain 130 374 3.8E-18 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 426 506 5.1E-15 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 PRINTS PR00110 Alpha-amylase signature 152 163 7.9E-22 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 PRINTS PR00110 Alpha-amylase signature 328 340 7.9E-22 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 PRINTS PR00110 Alpha-amylase signature 120 137 7.9E-22 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 PRINTS PR00110 Alpha-amylase signature 270 288 7.9E-22 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TL08_13470 15af939fda6ffe1963bb10a2c4a16dca 614 PRINTS PR00110 Alpha-amylase signature 241 252 7.9E-22 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TL08_16950 e0f1be6323285c79837db5a75d4160a2 436 Gene3D G3DSA:3.40.190.10 46 391 2.3E-58 T 12-10-2018 TL08_16950 e0f1be6323285c79837db5a75d4160a2 436 Pfam PF13416 Bacterial extracellular solute-binding protein 51 365 1.1E-24 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_16950 e0f1be6323285c79837db5a75d4160a2 436 Gene3D G3DSA:3.40.190.10 145 419 2.3E-58 T 12-10-2018 TL08_16950 e0f1be6323285c79837db5a75d4160a2 436 SUPERFAMILY SSF53850 39 431 1.09E-54 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1516 1901 9.2E-131 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SUPERFAMILY SSF56801 447 962 3.92E-61 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:3.40.50.1820 1991 2315 9.8E-94 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Pfam PF13193 AMP-binding enzyme C-terminal domain 849 924 1.7E-5 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Pfam PF13193 AMP-binding enzyme C-terminal domain 1886 1976 2.1E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Pfam PF00975 Thioesterase domain 2089 2307 1.1E-28 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:3.30.559.10 4 366 8.4E-111 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:3.30.559.30 1214 1462 4.9E-135 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:3.40.50.12780 440 834 1.3E-56 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:3.40.50.12780 1482 1872 7.3E-145 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SUPERFAMILY SSF52777 4 174 9.23E-36 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:3.30.559.10 1034 1404 4.9E-135 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:3.30.300.30 839 939 8.4E-16 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SMART SM00823 Phosphopantetheine attachment site 949 1018 0.001 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SMART SM00823 Phosphopantetheine attachment site 2001 2070 7.9E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2025 2040 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:3.30.559.30 178 419 8.4E-111 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Pfam PF00668 Condensation domain 1034 1476 5.2E-81 T 12-10-2018 IPR001242 Condensation domain TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Pfam PF00668 Condensation domain 4 433 1.9E-82 T 12-10-2018 IPR001242 Condensation domain TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SUPERFAMILY SSF52777 1029 1230 9.0E-44 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:1.10.1200.10 940 1021 4.2E-23 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15825 1047452b34da64c81b91795e4bebe945 2317 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1621 1632 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SUPERFAMILY SSF52777 181 424 1.67E-55 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SUPERFAMILY SSF56801 1465 2014 1.83E-151 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SUPERFAMILY SSF53474 2067 2313 3.21E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Pfam PF00501 AMP-binding enzyme 453 835 5.7E-25 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Pfam PF00501 AMP-binding enzyme 1496 1878 5.1E-98 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Gene3D G3DSA:3.30.300.30 1873 1990 7.8E-29 T 12-10-2018 TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SUPERFAMILY SSF47336 942 1014 2.22E-15 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SUPERFAMILY SSF47336 1994 2066 3.27E-17 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Pfam PF00550 Phosphopantetheine attachment site 951 1011 4.6E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15825 1047452b34da64c81b91795e4bebe945 2317 Pfam PF00550 Phosphopantetheine attachment site 2003 2066 1.4E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15825 1047452b34da64c81b91795e4bebe945 2317 SUPERFAMILY SSF52777 1219 1460 2.0E-55 T 12-10-2018 TL08_08220 0e9f4453062f1ee79cac2a8fef334c7a 74 Gene3D G3DSA:3.30.70.20 2 63 1.3E-14 T 12-10-2018 TL08_08220 0e9f4453062f1ee79cac2a8fef334c7a 74 SUPERFAMILY SSF54862 5 61 3.67E-9 T 12-10-2018 TL08_08220 0e9f4453062f1ee79cac2a8fef334c7a 74 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 8 59 2.7E-9 T 12-10-2018 TL08_08220 0e9f4453062f1ee79cac2a8fef334c7a 74 PRINTS PR00352 3Fe-4S ferredoxin signature 19 29 5.3E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_08220 0e9f4453062f1ee79cac2a8fef334c7a 74 PRINTS PR00352 3Fe-4S ferredoxin signature 8 19 5.3E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_08220 0e9f4453062f1ee79cac2a8fef334c7a 74 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 5.3E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_13460 f00cc099e2b6dd1e0730c0b0792708c8 425 SUPERFAMILY SSF53850 53 416 3.14E-64 T 12-10-2018 TL08_13460 f00cc099e2b6dd1e0730c0b0792708c8 425 Pfam PF13416 Bacterial extracellular solute-binding protein 70 369 2.8E-36 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_13460 f00cc099e2b6dd1e0730c0b0792708c8 425 Gene3D G3DSA:3.40.190.10 71 382 1.2E-70 T 12-10-2018 TL08_13460 f00cc099e2b6dd1e0730c0b0792708c8 425 Gene3D G3DSA:3.40.190.10 167 410 1.2E-70 T 12-10-2018 TL08_04495 4b7103dedd7e3fde1dae1d39df0ece72 200 Gene3D G3DSA:3.30.2030.20 53 200 5.4E-11 T 12-10-2018 TL08_04495 4b7103dedd7e3fde1dae1d39df0ece72 200 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 52 194 8.8E-36 T 12-10-2018 IPR032018 Putative lipoprotein, pathogenic bacteria TL08_12605 1c46972afc896a2d64f20cb2b420bb73 329 SUPERFAMILY SSF51735 115 273 4.21E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_12605 1c46972afc896a2d64f20cb2b420bb73 329 SMART SM00829 13 325 8.9E-44 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_12605 1c46972afc896a2d64f20cb2b420bb73 329 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TL08_12605 1c46972afc896a2d64f20cb2b420bb73 329 Gene3D G3DSA:3.90.180.10 15 321 5.8E-92 T 12-10-2018 TL08_12605 1c46972afc896a2d64f20cb2b420bb73 329 Gene3D G3DSA:3.40.50.720 126 270 5.8E-92 T 12-10-2018 TL08_12605 1c46972afc896a2d64f20cb2b420bb73 329 SUPERFAMILY SSF50129 2 141 3.2E-32 T 12-10-2018 IPR011032 GroES-like superfamily TL08_12605 1c46972afc896a2d64f20cb2b420bb73 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 3.1E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_12605 1c46972afc896a2d64f20cb2b420bb73 329 Pfam PF00107 Zinc-binding dehydrogenase 154 269 1.4E-29 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_18755 5d38f02d3f21b52b48c2470442c14d20 147 Gene3D G3DSA:1.10.10.10 5 144 1.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18755 5d38f02d3f21b52b48c2470442c14d20 147 SUPERFAMILY SSF46785 12 140 2.78E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_18755 5d38f02d3f21b52b48c2470442c14d20 147 Pfam PF01047 MarR family 33 91 1.4E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_18755 5d38f02d3f21b52b48c2470442c14d20 147 SMART SM00347 26 125 2.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 190 212 2.9E-28 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 169 184 2.9E-28 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 51 73 2.9E-28 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 223 235 2.9E-28 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 9 428 42.355 T 12-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 Gene3D G3DSA:3.40.50.620 7 229 3.6E-80 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 SUPERFAMILY SSF55174 334 426 1.02E-13 T 12-10-2018 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 SUPERFAMILY SSF52374 10 331 8.44E-90 T 12-10-2018 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 Gene3D G3DSA:1.10.240.10 230 334 1.7E-34 T 12-10-2018 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 57 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 Pfam PF00579 tRNA synthetases class I (W and Y) 37 331 9.1E-78 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 10 426 2.4E-102 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TL08_18085 75f7bc90997fb575e85d87343a3c1fb9 430 Gene3D G3DSA:3.10.290.10 335 430 6.4E-28 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TL08_21480 14a44ce6c32fdfdf409a492d918e421e 322 SUPERFAMILY SSF51735 129 291 6.44E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_21480 14a44ce6c32fdfdf409a492d918e421e 322 SMART SM00829 14 320 1.6E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_21480 14a44ce6c32fdfdf409a492d918e421e 322 Gene3D G3DSA:3.40.50.720 138 270 3.3E-72 T 12-10-2018 TL08_21480 14a44ce6c32fdfdf409a492d918e421e 322 SUPERFAMILY SSF50129 13 157 2.11E-27 T 12-10-2018 IPR011032 GroES-like superfamily TL08_21480 14a44ce6c32fdfdf409a492d918e421e 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 123 3.0E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_21480 14a44ce6c32fdfdf409a492d918e421e 322 Pfam PF00107 Zinc-binding dehydrogenase 168 284 3.5E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_21480 14a44ce6c32fdfdf409a492d918e421e 322 Gene3D G3DSA:3.90.180.10 22 313 3.3E-72 T 12-10-2018 TL08_10400 49e0148433f44362b7d474edf4d3910c 250 Gene3D G3DSA:3.30.70.980 134 206 4.5E-51 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_10400 49e0148433f44362b7d474edf4d3910c 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 3.1E-97 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_10400 49e0148433f44362b7d474edf4d3910c 250 Gene3D G3DSA:3.30.70.980 86 237 4.5E-51 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_10400 49e0148433f44362b7d474edf4d3910c 250 SUPERFAMILY SSF75625 3 246 4.05E-87 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_10400 49e0148433f44362b7d474edf4d3910c 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.135 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_10400 49e0148433f44362b7d474edf4d3910c 250 Gene3D G3DSA:1.10.10.200 1 80 1.5E-30 T 12-10-2018 IPR017856 Integrase-like, N-terminal TL08_10400 49e0148433f44362b7d474edf4d3910c 250 Pfam PF01709 Transcriptional regulator 5 238 2.1E-86 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_26735 8426556eaa24bed1ba4e1946d7c7cd0e 276 SUPERFAMILY SSF53850 10 270 8.83E-53 T 12-10-2018 TL08_26735 8426556eaa24bed1ba4e1946d7c7cd0e 276 SMART SM00062 50 272 6.3E-46 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_26735 8426556eaa24bed1ba4e1946d7c7cd0e 276 Gene3D G3DSA:3.40.190.10 57 270 1.1E-54 T 12-10-2018 TL08_26735 8426556eaa24bed1ba4e1946d7c7cd0e 276 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 54 270 1.2E-52 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_26735 8426556eaa24bed1ba4e1946d7c7cd0e 276 Gene3D G3DSA:3.40.190.10 136 228 1.1E-54 T 12-10-2018 TL08_26735 8426556eaa24bed1ba4e1946d7c7cd0e 276 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 71 84 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site TL08_16730 ed3f6ffe33d1b78543fc9a98285deb1d 110 Gene3D G3DSA:2.30.110.10 3 79 1.6E-7 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_16730 ed3f6ffe33d1b78543fc9a98285deb1d 110 Pfam PF04075 F420H(2)-dependent quinone reductase 15 65 6.3E-5 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_06235 44deb65fd4aba9fea4ca9a73dece756c 374 Gene3D G3DSA:3.30.9.10 89 334 7.3E-37 T 12-10-2018 TL08_06235 44deb65fd4aba9fea4ca9a73dece756c 374 SUPERFAMILY SSF51905 11 321 1.68E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06235 44deb65fd4aba9fea4ca9a73dece756c 374 Pfam PF01266 FAD dependent oxidoreductase 12 365 5.4E-37 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_06235 44deb65fd4aba9fea4ca9a73dece756c 374 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 12 365 3.2E-122 T 12-10-2018 IPR017741 FAD-dependent oxidoreductase, HpnW TL08_06235 44deb65fd4aba9fea4ca9a73dece756c 374 Gene3D G3DSA:3.50.50.60 12 368 7.3E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_11250 74fe410886a3dcb8b1b8f521734bbdf1 133 Pfam PF12680 SnoaL-like domain 20 116 3.3E-6 T 12-10-2018 IPR037401 SnoaL-like domain TL08_11250 74fe410886a3dcb8b1b8f521734bbdf1 133 SUPERFAMILY SSF54427 1 131 2.66E-18 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_11250 74fe410886a3dcb8b1b8f521734bbdf1 133 Gene3D G3DSA:3.10.450.50 2 126 5.2E-25 T 12-10-2018 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 Gene3D G3DSA:1.10.1140.10 359 476 1.8E-51 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 143 356 4.7E-62 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 SUPERFAMILY SSF52540 90 361 8.5E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 Gene3D G3DSA:2.40.10.170 9 88 4.1E-28 T 12-10-2018 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 Gene3D G3DSA:3.40.50.300 89 358 2.1E-100 T 12-10-2018 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 SUPERFAMILY SSF47917 359 474 1.83E-48 T 12-10-2018 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 SMART SM00382 155 341 7.6E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 Hamap MF_01347 ATP synthase subunit beta [atpB]. 10 474 54.131 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 12 472 1.1E-241 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 15 86 9.8E-23 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 SUPERFAMILY SSF50615 12 87 1.36E-23 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_07335 5a9cf451f70ddd8a27a77f52e892632b 476 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 347 356 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_10225 486c7ef09b8c44d4e09211ba59792425 147 Gene3D G3DSA:3.10.180.10 24 147 7.6E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_10225 486c7ef09b8c44d4e09211ba59792425 147 SUPERFAMILY SSF54593 22 139 2.89E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_10225 486c7ef09b8c44d4e09211ba59792425 147 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 23 139 6.9E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_11050 6b3d683b694427eb0d7c4931932df771 214 SUPERFAMILY SSF56784 13 176 1.31E-42 T 12-10-2018 IPR036412 HAD-like superfamily TL08_11050 6b3d683b694427eb0d7c4931932df771 214 Gene3D G3DSA:3.40.50.1000 4 180 2.1E-43 T 12-10-2018 IPR023214 HAD superfamily TL08_11050 6b3d683b694427eb0d7c4931932df771 214 Pfam PF13242 HAD-hyrolase-like 111 176 4.4E-11 T 12-10-2018 TL08_11050 6b3d683b694427eb0d7c4931932df771 214 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 18 157 7.4E-34 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 TL08_11050 6b3d683b694427eb0d7c4931932df771 214 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 18 156 8.2E-32 T 12-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 Pfam PF13424 Tetratricopeptide repeat 630 694 3.6E-9 T 12-10-2018 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 Pfam PF13424 Tetratricopeptide repeat 551 622 3.0E-12 T 12-10-2018 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 Gene3D G3DSA:3.40.50.300 55 223 3.0E-22 T 12-10-2018 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 Pfam PF00931 NB-ARC domain 90 282 1.2E-9 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SUPERFAMILY SSF52540 59 328 4.04E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 Gene3D G3DSA:1.25.40.10 464 561 4.9E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 Pfam PF13374 Tetratricopeptide repeat 712 743 0.0082 T 12-10-2018 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 Pfam PF13374 Tetratricopeptide repeat 511 543 1.8E-4 T 12-10-2018 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SMART SM00028 670 703 5.9 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SMART SM00028 510 543 18.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SMART SM00028 710 743 12.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SMART SM00028 883 916 33.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SMART SM00028 550 583 16.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SMART SM00028 843 876 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SMART SM00028 590 623 0.057 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SMART SM00028 630 663 1.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SUPERFAMILY SSF48452 475 622 1.52E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 Gene3D G3DSA:1.25.40.10 562 773 6.9E-52 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 PRINTS PR00364 Disease resistance protein signature 175 189 1.8E-9 T 12-10-2018 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 PRINTS PR00364 Disease resistance protein signature 265 279 1.8E-9 T 12-10-2018 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 PRINTS PR00364 Disease resistance protein signature 90 105 1.8E-9 T 12-10-2018 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 Gene3D G3DSA:1.25.40.10 780 933 1.5E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SUPERFAMILY SSF48452 820 918 4.74E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03165 04523029cd59e1f4929fbd5f8bdb07f8 941 SUPERFAMILY SSF48452 607 766 8.41E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_06695 4c9529eba2648d2c4453544a1b7f4264 364 Gene3D G3DSA:1.10.10.10 14 102 8.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06695 4c9529eba2648d2c4453544a1b7f4264 364 SUPERFAMILY SSF46785 23 98 2.73E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_06695 4c9529eba2648d2c4453544a1b7f4264 364 SUPERFAMILY SSF53335 115 328 7.41E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_06695 4c9529eba2648d2c4453544a1b7f4264 364 PIRSF PIRSF005739 11 344 1.9E-36 T 12-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 TL08_06695 4c9529eba2648d2c4453544a1b7f4264 364 Gene3D G3DSA:3.40.50.150 103 338 2.6E-57 T 12-10-2018 TL08_06695 4c9529eba2648d2c4453544a1b7f4264 364 Pfam PF00891 O-methyltransferase 113 327 2.8E-38 T 12-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 SUPERFAMILY SSF47789 837 900 6.15E-5 T 12-10-2018 TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 Pfam PF00069 Protein kinase domain 262 487 1.5E-8 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 Pfam PF00069 Protein kinase domain 568 784 2.3E-14 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 535 565 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 Pfam PF08378 Nuclease-related domain 26 145 5.6E-8 T 12-10-2018 IPR011528 Nuclease-related domain, NERD TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 Gene3D G3DSA:1.10.510.10 268 499 4.3E-20 T 12-10-2018 TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 SUPERFAMILY SSF56112 265 495 9.7E-22 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 Gene3D G3DSA:1.10.510.10 522 837 2.0E-21 T 12-10-2018 TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 SMART SM00220 529 794 1.1E-9 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_14380 c1801d3fb3926c00b4a9247b3348072a 1438 SUPERFAMILY SSF56112 521 795 2.08E-26 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_08305 5222580da61a8507532c113c9f21b165 324 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 284 310 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 87 312 5.4E-36 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 SUPERFAMILY SSF88659 164 237 2.01E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_08305 5222580da61a8507532c113c9f21b165 324 Gene3D G3DSA:1.10.10.10 164 239 1.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08305 5222580da61a8507532c113c9f21b165 324 Pfam PF04545 Sigma-70, region 4 259 312 1.1E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 Gene3D G3DSA:1.20.120.1810 25 160 1.3E-51 T 12-10-2018 TL08_08305 5222580da61a8507532c113c9f21b165 324 Gene3D G3DSA:1.10.10.10 247 324 6.5E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08305 5222580da61a8507532c113c9f21b165 324 SUPERFAMILY SSF88946 26 161 7.46E-52 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 Pfam PF04542 Sigma-70 region 2 91 160 5.2E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 PRINTS PR00046 Major sigma-70 factor signature 263 275 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 PRINTS PR00046 Major sigma-70 factor signature 299 310 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 PRINTS PR00046 Major sigma-70 factor signature 139 147 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 PRINTS PR00046 Major sigma-70 factor signature 284 299 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 PRINTS PR00046 Major sigma-70 factor signature 115 128 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 SUPERFAMILY SSF88659 221 319 4.3E-26 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_08305 5222580da61a8507532c113c9f21b165 324 Pfam PF00140 Sigma-70 factor, region 1.2 26 59 1.9E-13 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_08305 5222580da61a8507532c113c9f21b165 324 Pfam PF04539 Sigma-70 region 3 170 246 2.2E-23 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TL08_08305 5222580da61a8507532c113c9f21b165 324 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 115 128 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_19630 e5e1535f1200e8e4a3705d6323e9145f 211 Pfam PF13305 WHG domain 102 185 2.2E-10 T 12-10-2018 IPR025996 WHG domain TL08_19630 e5e1535f1200e8e4a3705d6323e9145f 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 65 9.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19630 e5e1535f1200e8e4a3705d6323e9145f 211 Gene3D G3DSA:1.10.357.10 12 209 1.1E-41 T 12-10-2018 TL08_19630 e5e1535f1200e8e4a3705d6323e9145f 211 SUPERFAMILY SSF46689 12 94 1.45E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_19630 e5e1535f1200e8e4a3705d6323e9145f 211 SUPERFAMILY SSF48498 99 187 1.11E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Pfam PF00550 Phosphopantetheine attachment site 974 1039 7.1E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 SUPERFAMILY SSF56801 427 983 2.09E-153 T 12-10-2018 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Pfam PF00975 Thioesterase domain 1067 1298 4.5E-7 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Gene3D G3DSA:3.30.300.30 857 958 1.3E-35 T 12-10-2018 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 SUPERFAMILY SSF53474 999 1298 4.95E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Pfam PF07690 Major Facilitator Superfamily 1349 1639 2.3E-8 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Pfam PF00501 AMP-binding enzyme 469 863 1.5E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 491 887 3.6E-127 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Gene3D G3DSA:3.40.50.1820 1050 1301 6.4E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Gene3D G3DSA:3.30.559.10 24 381 1.5E-137 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 SUPERFAMILY SSF52777 24 190 1.22E-46 T 12-10-2018 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Gene3D G3DSA:1.20.1250.20 1334 1741 3.3E-15 T 12-10-2018 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Pfam PF00668 Condensation domain 23 447 2.4E-91 T 12-10-2018 IPR001242 Condensation domain TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Gene3D G3DSA:1.10.1200.10 959 1043 2.5E-23 T 12-10-2018 IPR036736 ACP-like superfamily TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 SMART SM00823 Phosphopantetheine attachment site 972 1043 7.8E-7 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Gene3D G3DSA:3.30.559.30 194 434 1.5E-137 T 12-10-2018 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Gene3D G3DSA:3.40.50.12780 459 855 2.2E-126 T 12-10-2018 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 Pfam PF13193 AMP-binding enzyme C-terminal domain 871 945 9.8E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 SUPERFAMILY SSF52777 197 432 1.45E-56 T 12-10-2018 TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 SUPERFAMILY SSF103473 1337 1736 2.88E-20 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_05000 133e14aa21cb868c208c34d6b4a23b9b 1776 ProSitePatterns PS00455 Putative AMP-binding domain signature. 605 616 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_15390 4f4c2ddf50bfef890ca905409b836f2a 297 SUPERFAMILY SSF161098 59 285 1.83E-55 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15390 4f4c2ddf50bfef890ca905409b836f2a 297 Gene3D G3DSA:1.10.3720.10 53 296 2.7E-63 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15390 4f4c2ddf50bfef890ca905409b836f2a 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 291 3.9E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_15390 4f4c2ddf50bfef890ca905409b836f2a 297 SUPERFAMILY SSF160964 10 43 1.96E-6 T 12-10-2018 TL08_14555 362748b9639fabe358b479bed5715feb 715 Gene3D G3DSA:3.50.50.60 9 502 6.4E-86 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14555 362748b9639fabe358b479bed5715feb 715 Pfam PF05199 GMC oxidoreductase 439 496 1.7E-16 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 TL08_14555 362748b9639fabe358b479bed5715feb 715 SUPERFAMILY SSF51905 6 504 2.36E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14555 362748b9639fabe358b479bed5715feb 715 Pfam PF01266 FAD dependent oxidoreductase 8 269 4.1E-7 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_14555 362748b9639fabe358b479bed5715feb 715 Gene3D G3DSA:3.30.410.10 125 437 6.4E-86 T 12-10-2018 TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 Gene3D G3DSA:3.40.50.720 2 234 7.4E-79 T 12-10-2018 TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 5.1E-6 T 12-10-2018 TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 5.1E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.1E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 5.1E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 5.1E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 5.1E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 5.1E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 SUPERFAMILY SSF51735 3 230 2.31E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_10890 1da358315216f8ba9cc03f0d054b61e2 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 2.0E-58 T 12-10-2018 TL08_21380 1eaf487391d6067597fbafbecf1ec3d8 198 Gene3D G3DSA:3.40.390.30 2 154 4.6E-37 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 TL08_21380 1eaf487391d6067597fbafbecf1ec3d8 198 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 121 131 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site TL08_21380 1eaf487391d6067597fbafbecf1ec3d8 198 Pfam PF02130 Uncharacterized protein family UPF0054 22 150 4.2E-36 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TL08_21380 1eaf487391d6067597fbafbecf1ec3d8 198 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 151 2.6E-31 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TL08_21380 1eaf487391d6067597fbafbecf1ec3d8 198 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 3 156 21.312 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TL08_21380 1eaf487391d6067597fbafbecf1ec3d8 198 SUPERFAMILY SSF55486 10 153 1.27E-37 T 12-10-2018 TL08_12410 cc9171ad46897fc31396a7fcbfe8131e 193 SUPERFAMILY SSF46689 4 76 5.49E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_12410 cc9171ad46897fc31396a7fcbfe8131e 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_12410 cc9171ad46897fc31396a7fcbfe8131e 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_12410 cc9171ad46897fc31396a7fcbfe8131e 193 Gene3D G3DSA:1.10.357.10 54 182 2.0E-26 T 12-10-2018 TL08_12410 cc9171ad46897fc31396a7fcbfe8131e 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 56 1.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_12410 cc9171ad46897fc31396a7fcbfe8131e 193 Gene3D G3DSA:1.10.10.60 1 53 6.8E-19 T 12-10-2018 TL08_03810 95e77d0055ca52fa1b3e34070e2c7dfb 190 Pfam PF12867 DinB superfamily 13 174 2.1E-19 T 12-10-2018 IPR024775 DinB-like domain TL08_03810 95e77d0055ca52fa1b3e34070e2c7dfb 190 SUPERFAMILY SSF109854 9 182 1.96E-16 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 31 941 0.0 T 12-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 SUPERFAMILY SSF53732 8 668 2.49E-218 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 Pfam PF00694 Aconitase C-terminal domain 733 866 5.4E-41 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 ProSitePatterns PS00450 Aconitase family signature 1. 468 484 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 Pfam PF00330 Aconitase family (aconitate hydratase) 73 603 1.8E-176 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 SUPERFAMILY SSF52016 672 941 5.89E-83 T 12-10-2018 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 Gene3D G3DSA:3.20.19.10 694 942 9.8E-102 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 ProSitePatterns PS01244 Aconitase family signature 2. 534 547 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 Gene3D G3DSA:3.30.499.20 12 374 3.8E-154 T 12-10-2018 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 PRINTS PR00415 Aconitase family signature 205 218 9.3E-43 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 PRINTS PR00415 Aconitase family signature 295 308 9.3E-43 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 PRINTS PR00415 Aconitase family signature 145 158 9.3E-43 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 PRINTS PR00415 Aconitase family signature 219 234 9.3E-43 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 PRINTS PR00415 Aconitase family signature 472 483 9.3E-43 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 PRINTS PR00415 Aconitase family signature 169 177 9.3E-43 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 PRINTS PR00415 Aconitase family signature 374 388 9.3E-43 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 PRINTS PR00415 Aconitase family signature 281 294 9.3E-43 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 PRINTS PR00415 Aconitase family signature 534 547 9.3E-43 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TL08_10835 df7c40255073ac4cfc9d32590e0184f5 943 Gene3D G3DSA:1.10.1440.20 632 693 8.9E-20 T 12-10-2018 TL08_24465 60854c3a706e230a3bee6fd97d99837f 265 Gene3D G3DSA:3.60.10.10 1 265 8.3E-77 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_24465 60854c3a706e230a3bee6fd97d99837f 265 SUPERFAMILY SSF56219 2 264 7.07E-73 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_24465 60854c3a706e230a3bee6fd97d99837f 265 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 263 7.1E-73 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TL08_24465 60854c3a706e230a3bee6fd97d99837f 265 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 5 263 2.3E-71 T 12-10-2018 TL08_24465 60854c3a706e230a3bee6fd97d99837f 265 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 256 1.1E-19 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TL08_25655 d438846236891026f4bb2a5b586a6b4f 320 SUPERFAMILY SSF53448 20 235 1.07E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_25655 d438846236891026f4bb2a5b586a6b4f 320 Gene3D G3DSA:3.90.550.10 7 245 3.4E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_25655 d438846236891026f4bb2a5b586a6b4f 320 Pfam PF00535 Glycosyl transferase family 2 24 186 5.7E-23 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_10120 f998473188c3f8906ee574fc1d056fce 128 Gene3D G3DSA:1.10.260.40 2 68 1.3E-5 T 12-10-2018 TL08_10120 f998473188c3f8906ee574fc1d056fce 128 SUPERFAMILY SSF47413 7 68 5.96E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_02560 e11da7cc5c2cd361fa387e44fd33f38f 324 Pfam PF05138 Phenylacetic acid catabolic protein 26 300 1.1E-96 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 TL08_02560 e11da7cc5c2cd361fa387e44fd33f38f 324 SUPERFAMILY SSF47240 36 279 8.11E-76 T 12-10-2018 IPR009078 Ferritin-like superfamily TL08_02560 e11da7cc5c2cd361fa387e44fd33f38f 324 Gene3D G3DSA:1.20.1260.10 9 318 8.2E-126 T 12-10-2018 IPR012347 Ferritin-like TL08_02560 e11da7cc5c2cd361fa387e44fd33f38f 324 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 16 304 4.0E-146 T 12-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 TL08_18175 fa47d1d53411ce89384c5c8c91ab1685 270 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 28 100 5.1E-8 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TL08_18175 fa47d1d53411ce89384c5c8c91ab1685 270 SUPERFAMILY SSF75217 94 268 3.79E-38 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TL08_18175 fa47d1d53411ce89384c5c8c91ab1685 270 Pfam PF00588 SpoU rRNA Methylase family 117 261 6.9E-34 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TL08_18175 fa47d1d53411ce89384c5c8c91ab1685 270 Gene3D G3DSA:3.30.1330.30 3 102 6.7E-12 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_18175 fa47d1d53411ce89384c5c8c91ab1685 270 SMART SM00967 28 106 3.3E-9 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TL08_18175 fa47d1d53411ce89384c5c8c91ab1685 270 SUPERFAMILY SSF55315 6 102 1.88E-16 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_18175 fa47d1d53411ce89384c5c8c91ab1685 270 Gene3D G3DSA:3.40.1280.10 107 270 6.0E-50 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TL08_07435 12d5637e6669a4009e352032e24ea6e8 333 SUPERFAMILY SSF82549 11 332 3.4E-121 T 12-10-2018 TL08_07435 12d5637e6669a4009e352032e24ea6e8 333 Gene3D G3DSA:3.30.1180.20 185 333 9.8E-51 T 12-10-2018 TL08_07435 12d5637e6669a4009e352032e24ea6e8 333 Gene3D G3DSA:3.40.50.10440 11 184 8.3E-66 T 12-10-2018 TL08_07435 12d5637e6669a4009e352032e24ea6e8 333 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 2.7E-142 T 12-10-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 TL08_07435 12d5637e6669a4009e352032e24ea6e8 333 Pfam PF02733 Dak1 domain 18 328 3.6E-126 T 12-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TL08_04210 ee3e001fdcd26a4c09b764da76efc008 341 Gene3D G3DSA:3.40.1010.20 124 220 2.3E-111 T 12-10-2018 TL08_04210 ee3e001fdcd26a4c09b764da76efc008 341 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 28 311 37.338 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TL08_04210 ee3e001fdcd26a4c09b764da76efc008 341 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 30 308 8.4E-99 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TL08_04210 ee3e001fdcd26a4c09b764da76efc008 341 Pfam PF02401 LytB protein 30 307 1.7E-91 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TL08_04210 ee3e001fdcd26a4c09b764da76efc008 341 Gene3D G3DSA:3.40.1010.20 33 307 2.3E-111 T 12-10-2018 TL08_04210 ee3e001fdcd26a4c09b764da76efc008 341 Gene3D G3DSA:3.40.50.11270 39 123 2.3E-111 T 12-10-2018 TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 SUPERFAMILY SSF140453 83 152 9.55E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Gene3D G3DSA:3.90.930.1 900 1041 4.5E-6 T 12-10-2018 TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Gene3D G3DSA:3.90.930.1 643 784 9.9E-12 T 12-10-2018 TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Gene3D G3DSA:1.10.287.1060 78 168 2.9E-5 T 12-10-2018 TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Gene3D G3DSA:3.90.930.1 789 899 2.0E-5 T 12-10-2018 TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF05593 RHS Repeat 637 669 1.9E-5 T 12-10-2018 IPR031325 RHS repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF05593 RHS Repeat 613 649 7.6E-6 T 12-10-2018 IPR031325 RHS repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF05593 RHS Repeat 907 938 8.8E-5 T 12-10-2018 IPR031325 RHS repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF05593 RHS Repeat 696 732 5.1E-6 T 12-10-2018 IPR031325 RHS repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF05593 RHS Repeat 843 880 5.1E-12 T 12-10-2018 IPR031325 RHS repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF05593 RHS Repeat 946 980 1.9E-7 T 12-10-2018 IPR031325 RHS repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF05593 RHS Repeat 527 554 1.1E-4 T 12-10-2018 IPR031325 RHS repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF05593 RHS Repeat 739 774 3.6E-8 T 12-10-2018 IPR031325 RHS repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF14410 HNH/ENDO VII superfamily nuclease with conserved GHE residues 1590 1655 1.6E-9 T 12-10-2018 IPR026835 UPF0720 protein yqcG TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1322 1395 1.0E-23 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 527 562 7.8E-4 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 679 710 3.5E-5 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 886 924 0.0012 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 848 880 3.3E-9 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 696 736 1.2E-6 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 792 821 2.8E-4 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 613 653 3.1E-8 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 926 955 1.1E-5 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 738 777 1.9E-6 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 822 857 6.2E-4 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1180 1212 0.0024 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 637 673 7.7E-7 T 12-10-2018 IPR006530 YD repeat TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Pfam PF03527 RHS protein 1293 1325 8.6E-10 T 12-10-2018 IPR001826 RHS protein TL08_21630 37ccb121f6de77715e26ff87930116ca 1688 Gene3D G3DSA:2.180.10.10 1084 1395 7.7E-41 T 12-10-2018 TL08_14035 eee953eba867fc682192cc6ed71ce44b 160 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 24 1.5E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_14035 eee953eba867fc682192cc6ed71ce44b 160 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 1.5E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_14035 eee953eba867fc682192cc6ed71ce44b 160 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 24 37 1.5E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_14035 eee953eba867fc682192cc6ed71ce44b 160 SUPERFAMILY SSF46955 12 125 6.23E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_14035 eee953eba867fc682192cc6ed71ce44b 160 Pfam PF13411 MerR HTH family regulatory protein 12 78 7.5E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_14035 eee953eba867fc682192cc6ed71ce44b 160 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_14035 eee953eba867fc682192cc6ed71ce44b 160 Gene3D G3DSA:1.10.1660.10 7 135 4.1E-28 T 12-10-2018 TL08_14035 eee953eba867fc682192cc6ed71ce44b 160 SMART SM00422 12 80 2.2E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_05590 2f5bdbfcafed2656a27b1b5d849b40cd 113 Pfam PF03795 YCII-related domain 2 113 2.7E-17 T 12-10-2018 IPR005545 YCII-related TL08_05590 2f5bdbfcafed2656a27b1b5d849b40cd 113 Gene3D G3DSA:3.30.70.1060 1 113 5.1E-31 T 12-10-2018 TL08_05590 2f5bdbfcafed2656a27b1b5d849b40cd 113 SUPERFAMILY SSF54909 2 112 9.38E-25 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_25645 893a4eb0cb2e298d1fad97f94329c171 463 Pfam PF04932 O-Antigen ligase 231 358 6.2E-6 T 12-10-2018 IPR007016 O-antigen ligase-related TL08_22270 afd97f1054892403ada3ba160dfe35f5 112 PRINTS PR00340 P-II protein signature 52 75 2.1E-32 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TL08_22270 afd97f1054892403ada3ba160dfe35f5 112 PRINTS PR00340 P-II protein signature 2 17 2.1E-32 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TL08_22270 afd97f1054892403ada3ba160dfe35f5 112 PRINTS PR00340 P-II protein signature 83 103 2.1E-32 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TL08_22270 afd97f1054892403ada3ba160dfe35f5 112 PRINTS PR00340 P-II protein signature 23 41 2.1E-32 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TL08_22270 afd97f1054892403ada3ba160dfe35f5 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 TL08_22270 afd97f1054892403ada3ba160dfe35f5 112 Gene3D G3DSA:3.30.70.120 1 112 2.2E-37 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TL08_22270 afd97f1054892403ada3ba160dfe35f5 112 SUPERFAMILY SSF54913 2 112 5.08E-36 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TL08_22270 afd97f1054892403ada3ba160dfe35f5 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.1E-33 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TL08_22270 afd97f1054892403ada3ba160dfe35f5 112 SMART SM00938 4 105 3.4E-45 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TL08_15630 44133ee4cdc0bd008b4e1df328f9ac00 115 Gene3D G3DSA:3.30.70.100 1 98 5.3E-22 T 12-10-2018 TL08_15630 44133ee4cdc0bd008b4e1df328f9ac00 115 SUPERFAMILY SSF54909 16 96 9.65E-19 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_15630 44133ee4cdc0bd008b4e1df328f9ac00 115 Pfam PF07045 Domain of unknown function (DUF1330) 3 96 2.5E-22 T 12-10-2018 IPR010753 Domain of unknown function DUF1330 TL08_24085 aa9b5138cb08926816127cf385691dc8 407 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 362 5.7E-32 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_24085 aa9b5138cb08926816127cf385691dc8 407 SUPERFAMILY SSF53901 7 249 6.55E-59 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_24085 aa9b5138cb08926816127cf385691dc8 407 Gene3D G3DSA:3.40.47.10 258 407 2.2E-43 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_24085 aa9b5138cb08926816127cf385691dc8 407 SMART SM00825 Beta-ketoacyl synthase 9 395 1.4E-17 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_24085 aa9b5138cb08926816127cf385691dc8 407 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 158 174 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_24085 aa9b5138cb08926816127cf385691dc8 407 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 244 3.7E-43 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_24085 aa9b5138cb08926816127cf385691dc8 407 SUPERFAMILY SSF53901 212 405 4.07E-61 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_24085 aa9b5138cb08926816127cf385691dc8 407 Gene3D G3DSA:3.40.47.10 2 252 3.1E-69 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_09805 646d50df3e01faa8f91d492b1364d666 241 Gene3D G3DSA:3.40.50.300 5 231 3.6E-69 T 12-10-2018 TL08_09805 646d50df3e01faa8f91d492b1364d666 241 Hamap MF_00238 Cytidylate kinase [cmk]. 8 231 28.779 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TL08_09805 646d50df3e01faa8f91d492b1364d666 241 TIGRFAM TIGR00017 cmk: cytidylate kinase 9 220 9.5E-57 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TL08_09805 646d50df3e01faa8f91d492b1364d666 241 SUPERFAMILY SSF52540 9 227 8.77E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09805 646d50df3e01faa8f91d492b1364d666 241 Pfam PF02224 Cytidylate kinase 10 221 1.0E-60 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TL08_19400 9723f9994a613b99cee5f8bb91ba705f 229 Gene3D G3DSA:3.30.460.10 6 161 6.5E-51 T 12-10-2018 TL08_19400 9723f9994a613b99cee5f8bb91ba705f 229 Pfam PF04607 Region found in RelA / SpoT proteins 56 176 3.6E-36 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 TL08_19400 9723f9994a613b99cee5f8bb91ba705f 229 Gene3D G3DSA:1.10.287.860 162 223 4.8E-19 T 12-10-2018 TL08_19400 9723f9994a613b99cee5f8bb91ba705f 229 SUPERFAMILY SSF81301 18 208 7.68E-56 T 12-10-2018 TL08_19400 9723f9994a613b99cee5f8bb91ba705f 229 SMART SM00954 56 179 3.5E-45 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 Pfam PF01433 Peptidase family M1 domain 217 449 1.7E-57 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 SUPERFAMILY SSF63737 6 201 4.97E-39 T 12-10-2018 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 Pfam PF11838 ERAP1-like C-terminal domain 534 840 3.7E-60 T 12-10-2018 IPR024571 ERAP1-like C-terminal domain TL08_07920 b8fa68fdc5e244299714456193ba811d 852 Gene3D G3DSA:2.60.40.1730 19 202 1.6E-25 T 12-10-2018 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 847 0.0 T 12-10-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 SUPERFAMILY SSF55486 216 458 6.15E-77 T 12-10-2018 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 Gene3D G3DSA:1.10.390.60 210 454 2.8E-70 T 12-10-2018 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 137 152 1.2E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 267 277 1.2E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 301 316 1.2E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 320 332 1.2E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TL08_07920 b8fa68fdc5e244299714456193ba811d 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 1.2E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 8 817 23.271 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Gene3D G3DSA:3.30.1360.40 244 341 5.3E-199 T 12-10-2018 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 480 3.1E-149 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Gene3D G3DSA:1.10.268.10 378 466 5.3E-199 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 13 815 0.0 T 12-10-2018 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Gene3D G3DSA:3.90.199.10 36 494 5.3E-199 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 SMART SM00434 15 473 1.2E-271 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 SUPERFAMILY SSF56719 35 495 1.44E-168 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 SUPERFAMILY SSF101904 507 822 1.01E-99 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 769 809 1.6E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 720 766 4.2E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 619 663 9.5E-10 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 666 714 1.5E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 562 608 1.6E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 512 559 1.2E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TL08_00035 03ac3ab0441ef348e7199a874995db01 850 Gene3D G3DSA:2.120.10.90 509 817 6.0E-124 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TL08_05320 5cdf56bd76ee9ff3c87b5703e01c8caa 306 SUPERFAMILY SSF52540 12 241 3.68E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05320 5cdf56bd76ee9ff3c87b5703e01c8caa 306 Pfam PF00005 ABC transporter 32 169 1.6E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05320 5cdf56bd76ee9ff3c87b5703e01c8caa 306 Gene3D G3DSA:3.40.50.300 8 240 1.3E-55 T 12-10-2018 TL08_05320 5cdf56bd76ee9ff3c87b5703e01c8caa 306 SMART SM00382 40 225 4.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_25490 d94fa4e1e4e38600e5c82eae5dc3822f 373 Pfam PF00155 Aminotransferase class I and II 11 370 2.5E-61 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_25490 d94fa4e1e4e38600e5c82eae5dc3822f 373 Gene3D G3DSA:3.90.1150.10 1 370 9.1E-139 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_25490 d94fa4e1e4e38600e5c82eae5dc3822f 373 Gene3D G3DSA:3.40.640.10 23 270 9.1E-139 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_25490 d94fa4e1e4e38600e5c82eae5dc3822f 373 SUPERFAMILY SSF53383 8 372 6.18E-97 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_26225 a7cfe269d10f4680d3a900b65aa7fa6a 388 Gene3D G3DSA:2.30.40.10 21 385 3.4E-124 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_26225 a7cfe269d10f4680d3a900b65aa7fa6a 388 SUPERFAMILY SSF51556 66 359 2.94E-92 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_26225 a7cfe269d10f4680d3a900b65aa7fa6a 388 Pfam PF01979 Amidohydrolase family 63 373 1.2E-27 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_26225 a7cfe269d10f4680d3a900b65aa7fa6a 388 Gene3D G3DSA:3.20.20.140 67 353 3.4E-124 T 12-10-2018 TL08_26225 a7cfe269d10f4680d3a900b65aa7fa6a 388 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 16 380 2.2E-85 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 TL08_26225 a7cfe269d10f4680d3a900b65aa7fa6a 388 PIRSF PIRSF038994 15 388 5.5E-112 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 TL08_26225 a7cfe269d10f4680d3a900b65aa7fa6a 388 SUPERFAMILY SSF51338 12 374 5.23E-14 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_09045 95d4d3f0a72c587b3940a21df33f97d7 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 145 1.3E-14 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase TL08_09045 95d4d3f0a72c587b3940a21df33f97d7 146 SUPERFAMILY SSF55961 5 144 1.52E-10 T 12-10-2018 TL08_09045 95d4d3f0a72c587b3940a21df33f97d7 146 PIRSF PIRSF017371 1 145 3.3E-53 T 12-10-2018 IPR014488 Uncharacterised conserved protein UCP017371 TL08_17205 f98753243626865e3539b6d49c2dedd0 274 SUPERFAMILY SSF53098 20 201 9.49E-41 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_17205 f98753243626865e3539b6d49c2dedd0 274 Gene3D G3DSA:3.30.420.10 19 205 5.3E-36 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_17205 f98753243626865e3539b6d49c2dedd0 274 SMART SM00479 24 199 1.2E-17 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_17205 f98753243626865e3539b6d49c2dedd0 274 Pfam PF00929 Exonuclease 27 189 1.2E-12 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 8.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 8.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 SUPERFAMILY SSF51735 4 260 4.96E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 PIRSF PIRSF000126 2 266 7.4E-64 T 12-10-2018 TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 Pfam PF00106 short chain dehydrogenase 9 199 7.1E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 194 4.7E-4 T 12-10-2018 TL08_18750 da433d9e87114bef6d20997ad2633ccd 270 Gene3D G3DSA:3.40.50.720 1 257 1.8E-57 T 12-10-2018 TL08_02390 5751a4b7bc800d8dc62bad793549aafb 509 Gene3D G3DSA:3.40.1010.10 1 117 1.9E-25 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TL08_02390 5751a4b7bc800d8dc62bad793549aafb 509 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TL08_02390 5751a4b7bc800d8dc62bad793549aafb 509 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 203 6.8E-39 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TL08_02390 5751a4b7bc800d8dc62bad793549aafb 509 SUPERFAMILY SSF69618 238 489 4.84E-70 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02390 5751a4b7bc800d8dc62bad793549aafb 509 Gene3D G3DSA:3.40.50.10090 241 477 5.4E-50 T 12-10-2018 TL08_02390 5751a4b7bc800d8dc62bad793549aafb 509 SUPERFAMILY SSF53790 6 241 7.07E-49 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TL08_02390 5751a4b7bc800d8dc62bad793549aafb 509 Pfam PF02602 Uroporphyrinogen-III synthase HemD 252 482 5.3E-66 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_02390 5751a4b7bc800d8dc62bad793549aafb 509 Gene3D G3DSA:3.40.50.10090 270 410 5.4E-50 T 12-10-2018 TL08_02390 5751a4b7bc800d8dc62bad793549aafb 509 Gene3D G3DSA:3.30.950.10 118 234 6.2E-22 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 364 569 2.2E-35 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 Gene3D G3DSA:3.30.54.20 136 213 7.2E-57 T 12-10-2018 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 198 245 6.6E-13 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 SMART SM00863 189 245 1.4E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 72 674 32.87 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 Pfam PF03129 Anticodon binding domain 581 669 6.1E-18 T 12-10-2018 IPR004154 Anticodon-binding TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 SUPERFAMILY SSF52954 569 675 1.81E-28 T 12-10-2018 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 SUPERFAMILY SSF55681 269 565 2.11E-89 T 12-10-2018 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 Gene3D G3DSA:3.30.980.10 75 248 7.2E-57 T 12-10-2018 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 369 397 1.8E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 547 560 1.8E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 574 586 1.8E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 402 425 1.8E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 PRINTS PR01047 Threonyl-tRNA synthetase signature 505 533 1.8E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 Gene3D G3DSA:3.30.930.10 252 572 2.1E-114 T 12-10-2018 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 SUPERFAMILY SSF55186 70 266 3.53E-50 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 Gene3D G3DSA:3.40.50.800 573 680 6.7E-25 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily TL08_10335 ab1f8c9d8683d247b130b5290b794c8b 691 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 78 668 1.2E-190 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_00660 b5b5a3650e784f7da9e76cac40bd1583 270 Gene3D G3DSA:3.40.50.1000 5 267 3.1E-58 T 12-10-2018 IPR023214 HAD superfamily TL08_00660 b5b5a3650e784f7da9e76cac40bd1583 270 Gene3D G3DSA:3.30.1240.10 85 195 3.1E-58 T 12-10-2018 TL08_00660 b5b5a3650e784f7da9e76cac40bd1583 270 SUPERFAMILY SSF56784 5 270 5.56E-60 T 12-10-2018 IPR036412 HAD-like superfamily TL08_00660 b5b5a3650e784f7da9e76cac40bd1583 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 239 7.3E-22 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 TL08_00660 b5b5a3650e784f7da9e76cac40bd1583 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 266 5.2E-53 T 12-10-2018 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1081 1098 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 SUPERFAMILY SSF56059 84 351 1.94E-67 T 12-10-2018 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 SUPERFAMILY SSF51569 517 829 3.3E-75 T 12-10-2018 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1124 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 SUPERFAMILY SSF52440 1 112 1.8E-40 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.8E-39 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Pfam PF02785 Biotin carboxylase C-terminal domain 339 447 2.6E-34 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Gene3D G3DSA:3.30.470.130 1 454 1.4E-183 T 12-10-2018 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 PIRSF PIRSF001594 1 1125 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 SMART SM00878 339 446 8.1E-54 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 SUPERFAMILY SSF89000 826 991 1.69E-38 T 12-10-2018 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Pfam PF02436 Conserved carboxylase domain 821 1008 1.0E-51 T 12-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Gene3D G3DSA:2.40.50.100 1049 1123 2.9E-17 T 12-10-2018 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Gene3D G3DSA:3.20.20.70 476 989 8.4E-227 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 SUPERFAMILY SSF51246 334 452 1.94E-37 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 SUPERFAMILY SSF51230 1049 1124 4.84E-16 T 12-10-2018 IPR011053 Single hybrid motif TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Gene3D G3DSA:3.10.600.10 459 1040 8.4E-227 T 12-10-2018 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Pfam PF00682 HMGL-like 527 797 1.4E-30 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Pfam PF00364 Biotin-requiring enzyme 1066 1123 2.5E-13 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TL08_22430 97c5fa1a163e36a5355c1becb4d2037c 1125 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 322 1.1E-67 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_07755 387e2257cd23f9c3d66d13a377aef219 571 Pfam PF00561 alpha/beta hydrolase fold 116 503 4.2E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_07755 387e2257cd23f9c3d66d13a377aef219 571 SUPERFAMILY SSF53474 90 509 8.71E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Pfam PF00550 Phosphopantetheine attachment site 1424 1463 6.7E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Pfam PF08242 Methyltransferase domain 1172 1272 8.4E-11 T 12-10-2018 IPR013217 Methyltransferase type 12 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Pfam PF00668 Condensation domain 92 484 4.3E-29 T 12-10-2018 IPR001242 Condensation domain TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1446 1461 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 SUPERFAMILY SSF56801 512 1430 6.14E-129 T 12-10-2018 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 SUPERFAMILY SSF47336 1416 1501 1.7E-12 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 SUPERFAMILY SSF53474 1513 1820 4.06E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Gene3D G3DSA:1.10.1200.10 1415 1508 2.0E-22 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Gene3D G3DSA:3.40.50.12780 514 913 2.7E-122 T 12-10-2018 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Gene3D G3DSA:3.30.559.10 66 245 6.3E-46 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 ProSitePatterns PS00455 Putative AMP-binding domain signature. 663 674 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Gene3D G3DSA:3.30.559.30 249 494 2.8E-74 T 12-10-2018 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Gene3D G3DSA:3.40.50.150 1154 1310 3.1E-15 T 12-10-2018 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 SUPERFAMILY SSF52777 250 488 1.02E-37 T 12-10-2018 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Gene3D G3DSA:1.10.10.1830 3 54 6.9E-14 T 12-10-2018 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 545 945 2.9E-122 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Gene3D G3DSA:3.30.300.30 915 1025 8.5E-11 T 12-10-2018 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 SUPERFAMILY SSF52777 69 264 5.11E-25 T 12-10-2018 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Pfam PF00501 AMP-binding enzyme 527 921 1.6E-91 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 SUPERFAMILY SSF53335 1156 1329 2.97E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Pfam PF00975 Thioesterase domain 1532 1637 7.0E-9 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_14435 8c819493948f1d61889788f2589c2e1f 1825 Gene3D G3DSA:3.30.300.30 1325 1414 2.4E-12 T 12-10-2018 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 SUPERFAMILY SSF47446 330 430 3.92E-32 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 Gene3D G3DSA:1.20.120.140 5 308 1.0E-118 T 12-10-2018 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 6.9E-68 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 Gene3D G3DSA:3.40.50.300 90 287 1.0E-118 T 12-10-2018 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 7.6E-177 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 SMART SM00962 100 298 4.9E-107 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 SMART SM00963 1 86 1.7E-33 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 Gene3D G3DSA:1.10.260.30 312 436 1.2E-38 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 SUPERFAMILY SSF52540 42 356 2.43E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 SMART SM00382 99 303 2.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.1E-20 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 473 33.106 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 TL08_08740 26400a35688f54e12d19f2e3417e7b63 528 Pfam PF02978 Signal peptide binding domain 330 427 4.4E-29 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TL08_01240 a638274decd12e0444fe92aca6571d53 157 SUPERFAMILY SSF55298 8 156 9.9E-53 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_01240 a638274decd12e0444fe92aca6571d53 157 Gene3D G3DSA:3.30.1330.40 1 157 2.6E-58 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_01240 a638274decd12e0444fe92aca6571d53 157 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 12 155 2.7E-28 T 12-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like TL08_04465 dd86869b1f2d61b7485359adad230870 106 SUPERFAMILY SSF54862 3 94 5.07E-21 T 12-10-2018 TL08_04465 dd86869b1f2d61b7485359adad230870 106 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TL08_04465 dd86869b1f2d61b7485359adad230870 106 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.7E-17 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TL08_04465 dd86869b1f2d61b7485359adad230870 106 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.7E-17 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TL08_04465 dd86869b1f2d61b7485359adad230870 106 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.7E-17 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TL08_04465 dd86869b1f2d61b7485359adad230870 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TL08_04465 dd86869b1f2d61b7485359adad230870 106 Gene3D G3DSA:3.30.70.20 2 106 5.2E-46 T 12-10-2018 TL08_23900 db330874be8317294f1dd8d1f044cc13 359 Pfam PF02653 Branched-chain amino acid transport system / permease component 82 347 1.8E-45 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 366 556 8.6E-41 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 4 124 1.4E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SUPERFAMILY SSF48452 971 1175 1.77E-36 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SUPERFAMILY SSF48452 9 330 3.51E-43 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SUPERFAMILY SSF48452 831 1006 4.03E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 580 660 7.2E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 1175 1317 1.6E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 217 288 5.5E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 289 365 1.1E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 232 286 2.7E-6 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 401 462 0.0051 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 1008 1070 1.4E-8 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 605 662 0.0068 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 1112 1174 2.8E-8 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 307 360 4.9E-4 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 130 189 2.9E-5 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 1180 1234 0.0017 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 470 530 1.0E-5 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 707 769 7.0E-5 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Pfam PF13432 Tetratricopeptide repeat 874 935 2.8E-5 T 12-10-2018 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 125 216 3.2E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 1004 1074 6.6E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 906 1003 2.9E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 1075 1174 6.9E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SUPERFAMILY SSF48452 228 534 5.42E-45 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 668 701 18.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 736 769 16.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 158 191 0.0027 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 1072 1105 15.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 22 55 0.81 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 1208 1241 58.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 902 935 1.1E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 600 633 1.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 328 361 0.024 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 1004 1037 0.0025 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 1140 1173 0.26 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 124 157 0.74 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 294 327 0.0035 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 834 867 6.9 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 362 395 370.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 970 1003 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 430 463 0.002 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 1106 1139 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 1242 1275 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 770 803 4.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 56 89 7.5E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 634 667 0.078 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 90 123 0.048 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 396 429 7.9E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 226 259 0.0034 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 1174 1207 0.25 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 192 225 18.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 498 531 0.0017 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 868 901 7.8E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 260 293 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 464 497 0.0013 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 936 969 0.044 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 1038 1071 0.018 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SMART SM00028 702 735 3.2E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 Gene3D G3DSA:1.25.40.10 661 905 3.6E-45 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SUPERFAMILY SSF48452 1115 1314 7.21E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10565 9e432c1b66d79054ed9fca5df7fbe309 1354 SUPERFAMILY SSF48452 583 804 6.83E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 SUPERFAMILY SSF51905 14 324 7.48E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 Pfam PF14759 Reductase C-terminal 334 396 5.4E-12 T 12-10-2018 IPR028202 Reductase, C-terminal TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 Gene3D G3DSA:3.30.390.30 334 417 4.6E-13 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 18 315 9.9E-48 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 Gene3D G3DSA:3.50.50.60 19 315 3.0E-98 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 18 40 2.0E-18 T 12-10-2018 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 185 2.0E-18 T 12-10-2018 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 261 2.0E-18 T 12-10-2018 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 285 292 2.0E-18 T 12-10-2018 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 Gene3D G3DSA:3.50.50.60 129 253 3.0E-98 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 2.5E-21 T 12-10-2018 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 2.5E-21 T 12-10-2018 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 2.5E-21 T 12-10-2018 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 2.5E-21 T 12-10-2018 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 2.5E-21 T 12-10-2018 TL08_16210 e8d76b73905687d9b3541f27f52f88f7 421 SUPERFAMILY SSF55424 326 398 5.91E-18 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_06645 e1d38f3a2e8b67a2b6be7ef32041bc05 512 Pfam PF09210 Domain of unknown function (DUF1957) 410 505 7.9E-20 T 12-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TL08_06645 e1d38f3a2e8b67a2b6be7ef32041bc05 512 Pfam PF03065 Glycosyl hydrolase family 57 14 270 9.1E-20 T 12-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TL08_06645 e1d38f3a2e8b67a2b6be7ef32041bc05 512 SUPERFAMILY SSF88688 402 507 3.6E-18 T 12-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TL08_06645 e1d38f3a2e8b67a2b6be7ef32041bc05 512 SUPERFAMILY SSF88713 11 395 2.31E-92 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TL08_06645 e1d38f3a2e8b67a2b6be7ef32041bc05 512 Gene3D G3DSA:3.20.110.10 9 395 1.0E-108 T 12-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily TL08_06645 e1d38f3a2e8b67a2b6be7ef32041bc05 512 Gene3D G3DSA:1.20.1430.10 404 509 2.8E-17 T 12-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TL08_23420 8def89928782980701dac4b6189057cd 834 Pfam PF13692 Glycosyl transferases group 1 581 737 3.5E-11 T 12-10-2018 TL08_23420 8def89928782980701dac4b6189057cd 834 SUPERFAMILY SSF53756 378 769 6.8E-24 T 12-10-2018 TL08_23420 8def89928782980701dac4b6189057cd 834 Gene3D G3DSA:3.90.550.10 2 234 2.9E-45 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_23420 8def89928782980701dac4b6189057cd 834 SUPERFAMILY SSF53448 7 250 2.17E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_23420 8def89928782980701dac4b6189057cd 834 Pfam PF00535 Glycosyl transferase family 2 11 124 3.6E-17 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_23420 8def89928782980701dac4b6189057cd 834 Gene3D G3DSA:3.40.50.2000 570 751 4.2E-23 T 12-10-2018 TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 1.2E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 1.2E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 SMART SM00345 35 94 7.8E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 Gene3D G3DSA:1.10.10.10 29 98 3.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 SUPERFAMILY SSF46785 32 98 4.35E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 Gene3D G3DSA:3.40.640.10 145 367 1.3E-77 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 94 1.9E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 SUPERFAMILY SSF53383 109 472 6.05E-73 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 Gene3D G3DSA:3.90.1150.10 127 470 1.3E-77 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_25595 009b7b943e52014bd2ac5638529dd6c9 491 Pfam PF00155 Aminotransferase class I and II 150 468 4.1E-22 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_18535 017d6efc00466c9ccce4c2c6aa81791e 459 Pfam PF01494 FAD binding domain 13 349 1.9E-11 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_18535 017d6efc00466c9ccce4c2c6aa81791e 459 Gene3D G3DSA:3.30.9.50 62 304 1.3E-27 T 12-10-2018 TL08_18535 017d6efc00466c9ccce4c2c6aa81791e 459 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 1.0E-5 T 12-10-2018 TL08_18535 017d6efc00466c9ccce4c2c6aa81791e 459 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 1.0E-5 T 12-10-2018 TL08_18535 017d6efc00466c9ccce4c2c6aa81791e 459 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 329 1.0E-5 T 12-10-2018 TL08_18535 017d6efc00466c9ccce4c2c6aa81791e 459 Gene3D G3DSA:3.50.50.60 13 350 1.3E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_18535 017d6efc00466c9ccce4c2c6aa81791e 459 SUPERFAMILY SSF51905 12 358 1.3E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_08975 ba451ea3238ee2b2884526a94f91af9f 508 SUPERFAMILY SSF52317 252 427 2.78E-36 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_08975 ba451ea3238ee2b2884526a94f91af9f 508 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 434 1.2E-47 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TL08_08975 ba451ea3238ee2b2884526a94f91af9f 508 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 1 224 6.2E-23 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TL08_08975 ba451ea3238ee2b2884526a94f91af9f 508 SUPERFAMILY SSF52540 1 233 3.54E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08975 ba451ea3238ee2b2884526a94f91af9f 508 Gene3D G3DSA:3.40.50.880 254 464 8.7E-25 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_08975 ba451ea3238ee2b2884526a94f91af9f 508 Gene3D G3DSA:3.40.50.300 1 237 6.5E-50 T 12-10-2018 TL08_08975 ba451ea3238ee2b2884526a94f91af9f 508 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 1 482 2.9E-145 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TL08_08975 ba451ea3238ee2b2884526a94f91af9f 508 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 491 178.505 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TL08_20405 65bb0c6a94a22c1b0c659eb2309755f2 163 Gene3D G3DSA:3.30.60.230 1 59 5.6E-25 T 12-10-2018 TL08_20405 65bb0c6a94a22c1b0c659eb2309755f2 163 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 90 9.0E-14 T 12-10-2018 IPR024412 Lsr2 TL08_20405 65bb0c6a94a22c1b0c659eb2309755f2 163 Pfam PF11774 Lsr2 1 94 1.4E-23 T 12-10-2018 IPR024412 Lsr2 TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 Pfam PF00005 ABC transporter 27 184 5.2E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 518 542 7.6E-6 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 266 1.0E-4 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 SMART SM00382 34 233 2.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 SMART SM00382 324 516 6.4E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 SUPERFAMILY SSF52540 295 538 1.74E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 Pfam PF00005 ABC transporter 316 466 2.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 SUPERFAMILY SSF52540 6 255 1.09E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 Gene3D G3DSA:3.40.50.300 291 567 5.8E-83 T 12-10-2018 TL08_12770 4b20c6940ecc947408d5dfa53b8c5c36 574 Gene3D G3DSA:3.40.50.300 3 290 5.4E-81 T 12-10-2018 TL08_10915 09f7376452acc1decdb636e2ec9b4ceb 275 Pfam PF11296 Protein of unknown function (DUF3097) 10 271 2.1E-116 T 12-10-2018 IPR021447 Protein of unknown function DUF3097 TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 639 790 8.7E-29 T 12-10-2018 TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 SUPERFAMILY SSF49303 194 288 6.91E-14 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 Gene3D G3DSA:3.20.20.80 298 576 4.0E-47 T 12-10-2018 TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 SUPERFAMILY SSF51445 284 571 4.22E-57 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 Pfam PF00703 Glycosyl hydrolases family 2 195 287 5.5E-10 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 Gene3D G3DSA:2.60.40.10 193 287 2.9E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 Gene3D G3DSA:2.60.120.260 23 191 7.3E-40 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 SUPERFAMILY SSF49785 19 191 1.08E-45 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 SMART SM00560 655 787 2.2E-24 T 12-10-2018 IPR006558 LamG-like jellyroll fold TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 Gene3D G3DSA:2.60.120.200 596 793 1.1E-36 T 12-10-2018 TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 63 185 6.3E-12 T 12-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_15190 47a35c81cf06d6461f917e86fd2b5931 804 SUPERFAMILY SSF49899 600 794 2.53E-33 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 156 323 3.4E-33 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 PIRSF PIRSF000185 6 391 3.6E-82 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 Gene3D G3DSA:3.40.50.720 156 388 2.0E-43 T 12-10-2018 TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 SMART SM00839 161 388 2.9E-41 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 58 72 7.1E-7 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 189 209 7.1E-7 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 SUPERFAMILY SSF51735 156 383 8.99E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 12 122 7.7E-19 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 Gene3D G3DSA:3.40.50.10860 9 125 5.0E-27 T 12-10-2018 TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 66 79 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TL08_07190 16f2a8c67cd66303f828c5a94c1b9430 397 SUPERFAMILY SSF53223 10 128 2.43E-29 T 12-10-2018 TL08_05990 347a14f13710025ac121f6e160e624d0 174 Gene3D G3DSA:1.10.1740.10 3 83 1.6E-7 T 12-10-2018 TL08_05990 347a14f13710025ac121f6e160e624d0 174 Pfam PF08281 Sigma-70, region 4 112 162 3.1E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_05990 347a14f13710025ac121f6e160e624d0 174 SUPERFAMILY SSF88946 14 79 5.49E-8 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_05990 347a14f13710025ac121f6e160e624d0 174 Gene3D G3DSA:1.10.10.10 99 168 6.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05990 347a14f13710025ac121f6e160e624d0 174 SUPERFAMILY SSF88659 107 165 3.36E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 Gene3D G3DSA:3.40.47.10 393 624 4.1E-30 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 Gene3D G3DSA:3.40.47.10 1 226 3.8E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 SMART SM00825 Beta-ketoacyl synthase 6 396 6.1E-14 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 SUPERFAMILY SSF53901 590 726 4.55E-10 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 Gene3D G3DSA:3.40.47.10 628 765 7.3E-6 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 SUPERFAMILY SSF53901 4 224 2.19E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 226 340 1.6E-32 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 Gene3D G3DSA:3.40.47.10 228 383 3.9E-46 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 SUPERFAMILY SSF53901 190 393 1.37E-54 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 216 9.2E-32 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 455 577 1.8E-11 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_05695 9e82f949557a22adcb6339c832dc80bc 766 SUPERFAMILY SSF53901 406 620 1.3E-27 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_08800 4ef5da027ed62e1215f25c7cb0e1764e 421 SUPERFAMILY SSF53067 82 394 7.41E-54 T 12-10-2018 TL08_08800 4ef5da027ed62e1215f25c7cb0e1764e 421 Pfam PF00480 ROK family 85 393 4.7E-56 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_08800 4ef5da027ed62e1215f25c7cb0e1764e 421 SUPERFAMILY SSF46785 12 74 4.62E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_08800 4ef5da027ed62e1215f25c7cb0e1764e 421 Gene3D G3DSA:1.10.10.10 3 77 2.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_08800 4ef5da027ed62e1215f25c7cb0e1764e 421 Pfam PF13412 Winged helix-turn-helix DNA-binding 18 57 1.3E-5 T 12-10-2018 TL08_08800 4ef5da027ed62e1215f25c7cb0e1764e 421 Gene3D G3DSA:3.30.420.40 95 389 7.9E-84 T 12-10-2018 TL08_08800 4ef5da027ed62e1215f25c7cb0e1764e 421 Gene3D G3DSA:3.30.420.40 206 379 7.9E-84 T 12-10-2018 TL08_08800 4ef5da027ed62e1215f25c7cb0e1764e 421 ProSitePatterns PS01125 ROK family signature. 216 243 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.4E-41 T 12-10-2018 TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 1.4E-41 T 12-10-2018 TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 332 1.4E-41 T 12-10-2018 TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 348 1.4E-41 T 12-10-2018 TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 1.4E-41 T 12-10-2018 TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 1.4E-41 T 12-10-2018 TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 Gene3D G3DSA:3.50.50.60 9 347 2.4E-96 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 Pfam PF01494 FAD binding domain 8 346 1.2E-66 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 Gene3D G3DSA:3.30.70.2450 188 270 2.4E-96 T 12-10-2018 TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 SUPERFAMILY SSF51905 7 377 1.04E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_19810 9aba56f4100324e7628de9e57e221e1b 507 Gene3D G3DSA:3.40.30.120 418 501 2.8E-6 T 12-10-2018 TL08_06625 882dbe8f876ef8f20a460f11dc8f3a71 262 Gene3D G3DSA:2.160.10.10 50 225 4.3E-31 T 12-10-2018 TL08_06625 882dbe8f876ef8f20a460f11dc8f3a71 262 SUPERFAMILY SSF51161 30 218 3.42E-30 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TL08_06625 882dbe8f876ef8f20a460f11dc8f3a71 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 159 190 4.9E-6 T 12-10-2018 IPR001451 Hexapeptide repeat TL08_04165 9e3776f6069cbff32a8d632d60277c93 287 Gene3D G3DSA:2.40.10.10 48 286 2.8E-40 T 12-10-2018 TL08_04165 9e3776f6069cbff32a8d632d60277c93 287 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 225 236 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site TL08_04165 9e3776f6069cbff32a8d632d60277c93 287 SUPERFAMILY SSF50494 51 285 1.1E-48 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_04165 9e3776f6069cbff32a8d632d60277c93 287 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 81 96 5.2E-14 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_04165 9e3776f6069cbff32a8d632d60277c93 287 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 139 153 5.2E-14 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_04165 9e3776f6069cbff32a8d632d60277c93 287 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 224 236 5.2E-14 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_04165 9e3776f6069cbff32a8d632d60277c93 287 Pfam PF00089 Trypsin 55 269 6.0E-34 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_04165 9e3776f6069cbff32a8d632d60277c93 287 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 91 96 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 TL08_04165 9e3776f6069cbff32a8d632d60277c93 287 SMART SM00020 54 281 5.0E-38 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_21890 882b1cf6aff77515515d825ca99dca70 311 SUPERFAMILY SSF51735 13 261 1.15E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_21890 882b1cf6aff77515515d825ca99dca70 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 4.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21890 882b1cf6aff77515515d825ca99dca70 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 4.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21890 882b1cf6aff77515515d825ca99dca70 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 4.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21890 882b1cf6aff77515515d825ca99dca70 311 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 4.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21890 882b1cf6aff77515515d825ca99dca70 311 Gene3D G3DSA:3.40.50.720 1 308 4.5E-80 T 12-10-2018 TL08_21890 882b1cf6aff77515515d825ca99dca70 311 Pfam PF00106 short chain dehydrogenase 15 220 3.0E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15355 9975d40988351114b9a89ecf2c766bc7 233 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 27 221 8.3E-28 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_15355 9975d40988351114b9a89ecf2c766bc7 233 Gene3D G3DSA:3.40.50.970 15 231 3.0E-52 T 12-10-2018 TL08_15355 9975d40988351114b9a89ecf2c766bc7 233 SUPERFAMILY SSF52518 27 227 1.41E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_14675 2037200cce33b3e41e383afdfabbeab3 491 Gene3D G3DSA:3.20.20.80 43 395 3.6E-31 T 12-10-2018 TL08_14675 2037200cce33b3e41e383afdfabbeab3 491 SUPERFAMILY SSF51445 38 398 2.34E-23 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 Gene3D G3DSA:3.30.930.10 1 292 3.1E-97 T 12-10-2018 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 Pfam PF03129 Anticodon binding domain 305 393 3.5E-6 T 12-10-2018 IPR004154 Anticodon-binding TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 298 310 9.1E-44 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 91 119 9.1E-44 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 124 147 9.1E-44 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 228 256 9.1E-44 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 271 284 9.1E-44 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 86 292 1.5E-27 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 2 394 2.1E-132 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 SUPERFAMILY SSF55681 3 290 9.12E-78 T 12-10-2018 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 SUPERFAMILY SSF52954 293 395 2.29E-15 T 12-10-2018 TL08_26900 c5d6294e0abe2e33f026fa7578155f2e 409 Gene3D G3DSA:3.40.50.800 295 402 3.7E-14 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily TL08_03840 3de83b28baa39d5b46b18cb6a46361b2 507 Pfam PF09594 Glycosyltransferase family 87 89 322 7.8E-55 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 TL08_24750 99ffb7ec9f3736eea1709b6ce0f1e9e9 213 SUPERFAMILY SSF51735 1 212 3.96E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24750 99ffb7ec9f3736eea1709b6ce0f1e9e9 213 Gene3D G3DSA:3.40.50.720 2 212 4.9E-47 T 12-10-2018 TL08_24750 99ffb7ec9f3736eea1709b6ce0f1e9e9 213 Pfam PF13460 NAD(P)H-binding 7 198 1.1E-23 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_21970 d9319050146789d39c6d6918f49e60f6 1306 Pfam PF05050 Methyltransferase FkbM domain 1081 1270 3.5E-9 T 12-10-2018 IPR006342 Methyltransferase FkbM TL08_21970 d9319050146789d39c6d6918f49e60f6 1306 Gene3D G3DSA:3.40.50.150 1069 1272 1.6E-21 T 12-10-2018 TL08_21970 d9319050146789d39c6d6918f49e60f6 1306 Gene3D G3DSA:3.40.50.2000 591 779 2.5E-15 T 12-10-2018 TL08_21970 d9319050146789d39c6d6918f49e60f6 1306 SUPERFAMILY SSF53756 554 795 1.07E-14 T 12-10-2018 TL08_21970 d9319050146789d39c6d6918f49e60f6 1306 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 1078 1245 5.9E-14 T 12-10-2018 IPR006342 Methyltransferase FkbM TL08_21970 d9319050146789d39c6d6918f49e60f6 1306 SUPERFAMILY SSF53335 1023 1271 2.95E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_18710 32ac39068528c09d7d2ce61fa6c16397 487 Pfam PF01229 Glycosyl hydrolases family 39 82 261 2.9E-4 T 12-10-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 TL08_18710 32ac39068528c09d7d2ce61fa6c16397 487 SUPERFAMILY SSF51445 35 393 4.76E-21 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_18710 32ac39068528c09d7d2ce61fa6c16397 487 Gene3D G3DSA:3.20.20.80 39 392 1.4E-30 T 12-10-2018 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 SUPERFAMILY SSF47323 775 962 5.05E-34 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 597 615 7.4E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 292 311 7.4E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 682 692 7.4E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 649 671 7.4E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 170 7.4E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 263 276 7.4E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Pfam PF09334 tRNA synthetases class I (M) 65 168 5.3E-12 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 224 963 3.7E-215 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 69 79 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 298 501 5.2E-55 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 21 963 21.128 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Gene3D G3DSA:1.10.730.10 755 902 5.2E-192 T 12-10-2018 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Gene3D G3DSA:3.10.330.110 706 754 5.2E-192 T 12-10-2018 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Gene3D G3DSA:3.10.20.590 905 963 9.9E-21 T 12-10-2018 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Gene3D G3DSA:3.40.50.620 222 704 5.2E-192 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 SUPERFAMILY SSF52374 26 780 5.63E-104 T 12-10-2018 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Gene3D G3DSA:3.40.50.620 57 174 4.4E-38 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Pfam PF08264 Anticodon-binding domain of tRNA 810 929 2.2E-17 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 Gene3D G3DSA:3.90.740.10 312 525 5.2E-192 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TL08_27005 478a4b62922a500290ac5ecd6d677b03 963 SUPERFAMILY SSF50677 303 512 9.42E-44 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TL08_16385 535331ea6efe6222e37eda43cb3892b2 286 SUPERFAMILY SSF52540 65 266 1.78E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_16385 535331ea6efe6222e37eda43cb3892b2 286 Gene3D G3DSA:3.40.50.300 52 283 2.6E-36 T 12-10-2018 TL08_16385 535331ea6efe6222e37eda43cb3892b2 286 Pfam PF00005 ABC transporter 72 212 3.0E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_02465 d5bab1684a03f6281511cf26bf5412b2 471 SUPERFAMILY SSF52540 219 433 9.07E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_02465 d5bab1684a03f6281511cf26bf5412b2 471 Gene3D G3DSA:3.40.50.300 220 443 2.4E-33 T 12-10-2018 TL08_02465 d5bab1684a03f6281511cf26bf5412b2 471 Pfam PF13614 AAA domain 220 364 7.4E-11 T 12-10-2018 IPR025669 AAA domain TL08_02750 60b8775ca951160c28d9c38023a45f09 299 SMART SM00220 7 266 6.7E-47 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_02750 60b8775ca951160c28d9c38023a45f09 299 SUPERFAMILY SSF56112 4 264 3.51E-68 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_02750 60b8775ca951160c28d9c38023a45f09 299 Gene3D G3DSA:3.30.200.20 1 87 3.8E-23 T 12-10-2018 TL08_02750 60b8775ca951160c28d9c38023a45f09 299 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 14 37 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_02750 60b8775ca951160c28d9c38023a45f09 299 Pfam PF00069 Protein kinase domain 13 253 8.3E-40 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_02750 60b8775ca951160c28d9c38023a45f09 299 Gene3D G3DSA:1.10.510.10 89 268 4.5E-44 T 12-10-2018 TL08_02750 60b8775ca951160c28d9c38023a45f09 299 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_09070 713e6183278e2cd50438e63d6e14a209 306 Gene3D G3DSA:3.30.1380.10 161 302 7.6E-13 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TL08_09070 713e6183278e2cd50438e63d6e14a209 306 SUPERFAMILY SSF55166 149 303 1.49E-23 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TL08_09070 713e6183278e2cd50438e63d6e14a209 306 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 226 302 1.8E-16 T 12-10-2018 IPR039561 Peptidase M15C GO:0008233 TL08_19320 4b0a367d021c5882971a5f54696e05e1 180 Gene3D G3DSA:3.40.430.10 1 173 1.8E-32 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_19320 4b0a367d021c5882971a5f54696e05e1 180 Pfam PF01872 RibD C-terminal domain 5 167 4.6E-16 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TL08_19320 4b0a367d021c5882971a5f54696e05e1 180 SUPERFAMILY SSF53597 6 170 8.51E-23 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 Pfam PF01434 Peptidase family M41 395 602 2.0E-76 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 ProSitePatterns PS00674 AAA-protein family signature. 303 321 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 SMART SM00382 196 335 5.4E-25 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 SUPERFAMILY SSF140990 414 607 9.55E-68 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 Gene3D G3DSA:1.10.8.60 334 411 1.7E-25 T 12-10-2018 TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 Gene3D G3DSA:3.40.50.300 151 332 1.9E-68 T 12-10-2018 TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 113 603 2.7E-225 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 200 331 1.8E-45 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 SUPERFAMILY SSF52540 156 403 6.1E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 611 36.071 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TL08_01665 44a962ff84baf973c9dc2c3a8ae57008 806 Gene3D G3DSA:1.20.58.760 414 615 4.3E-69 T 12-10-2018 TL08_06250 17490abf1a0541cd72b83f2f1228551d 804 Gene3D G3DSA:1.10.439.10 38 211 8.0E-49 T 12-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 TL08_06250 17490abf1a0541cd72b83f2f1228551d 804 Gene3D G3DSA:1.10.1400.10 529 724 1.6E-190 T 12-10-2018 TL08_06250 17490abf1a0541cd72b83f2f1228551d 804 Gene3D G3DSA:3.60.20.10 232 789 1.6E-190 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_06250 17490abf1a0541cd72b83f2f1228551d 804 Gene3D G3DSA:2.30.120.10 308 384 1.6E-190 T 12-10-2018 TL08_06250 17490abf1a0541cd72b83f2f1228551d 804 SUPERFAMILY SSF56235 42 795 2.57E-137 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_06250 17490abf1a0541cd72b83f2f1228551d 804 Pfam PF01804 Penicillin amidase 47 790 3.5E-115 T 12-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 SUPERFAMILY SSF51905 9 359 2.8E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 Gene3D G3DSA:3.40.30.120 389 531 8.5E-47 T 12-10-2018 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 Gene3D G3DSA:3.30.9.50 76 291 2.2E-100 T 12-10-2018 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 3.3E-36 T 12-10-2018 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 325 3.3E-36 T 12-10-2018 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 309 3.3E-36 T 12-10-2018 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 345 3.3E-36 T 12-10-2018 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 345 361 3.3E-36 T 12-10-2018 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 3.3E-36 T 12-10-2018 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 Pfam PF01494 FAD binding domain 9 356 2.9E-89 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_15625 4e61fc3d0533137294886487fc9f26f8 531 Gene3D G3DSA:3.50.50.60 10 352 2.2E-100 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 Gene3D G3DSA:3.30.540.10 2 148 9.0E-40 T 12-10-2018 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 Pfam PF00459 Inositol monophosphatase family 9 267 9.4E-58 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 219 233 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 90 103 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 Gene3D G3DSA:3.40.190.80 150 273 9.3E-33 T 12-10-2018 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 SUPERFAMILY SSF56655 9 269 9.29E-69 T 12-10-2018 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 47 67 4.8E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 216 240 4.8E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 185 206 4.8E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 139 162 4.8E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 90 106 4.8E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_08390 fff4d95dc180b4f997e0432c83c74dd9 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 69 85 4.8E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_08820 01b71fa30c3d4ec41f83fc6ca71605f9 368 SUPERFAMILY SSF52540 53 340 5.68E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08820 01b71fa30c3d4ec41f83fc6ca71605f9 368 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 257 321 2.0E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_08820 01b71fa30c3d4ec41f83fc6ca71605f9 368 Pfam PF00005 ABC transporter 46 205 1.5E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_08820 01b71fa30c3d4ec41f83fc6ca71605f9 368 SMART SM00382 53 255 1.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08820 01b71fa30c3d4ec41f83fc6ca71605f9 368 Gene3D G3DSA:3.40.50.300 23 347 3.3E-93 T 12-10-2018 TL08_08820 01b71fa30c3d4ec41f83fc6ca71605f9 368 ProSitePatterns PS00211 ABC transporters family signature. 178 192 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_08820 01b71fa30c3d4ec41f83fc6ca71605f9 368 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 255 337 5.2E-23 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_16095 f11c360736ff80719ad168e58f37c7a7 843 Gene3D G3DSA:1.20.1640.10 613 803 6.1E-7 T 12-10-2018 TL08_16095 f11c360736ff80719ad168e58f37c7a7 843 SUPERFAMILY SSF82866 252 446 1.57E-25 T 12-10-2018 TL08_16095 f11c360736ff80719ad168e58f37c7a7 843 SUPERFAMILY SSF82866 567 804 1.18E-29 T 12-10-2018 TL08_16095 f11c360736ff80719ad168e58f37c7a7 843 Pfam PF03176 MMPL family 552 805 2.6E-32 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TL08_16095 f11c360736ff80719ad168e58f37c7a7 843 Pfam PF03176 MMPL family 204 454 8.3E-42 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TL08_12745 2dc8136b2d188644868c3598cc7643b9 344 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 53 324 4.4E-36 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TL08_12745 2dc8136b2d188644868c3598cc7643b9 344 SUPERFAMILY SSF53822 55 211 6.28E-5 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_12745 2dc8136b2d188644868c3598cc7643b9 344 Gene3D G3DSA:3.40.50.2300 139 336 2.8E-62 T 12-10-2018 TL08_12745 2dc8136b2d188644868c3598cc7643b9 344 Gene3D G3DSA:3.40.50.2300 49 294 2.8E-62 T 12-10-2018 TL08_14185 f365ba571cd3b03f00d7dab27b73927c 486 Gene3D G3DSA:3.90.1300.10 4 481 2.4E-131 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_14185 f365ba571cd3b03f00d7dab27b73927c 486 Pfam PF01425 Amidase 35 455 2.0E-87 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_14185 f365ba571cd3b03f00d7dab27b73927c 486 ProSitePatterns PS00571 Amidases signature. 145 176 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TL08_14185 f365ba571cd3b03f00d7dab27b73927c 486 SUPERFAMILY SSF75304 5 476 3.4E-113 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 Gene3D G3DSA:1.10.1040.10 162 292 4.3E-47 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 1.9E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 1.9E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 1.9E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 151 179 1.9E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 226 253 1.9E-34 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 Gene3D G3DSA:3.40.50.720 1 161 8.6E-45 T 12-10-2018 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 162 272 2.9E-23 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 230 242 - T 12-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 SUPERFAMILY SSF51735 2 144 7.89E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 143 1.4E-36 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 SMART SM01350 162 306 3.8E-5 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 SUPERFAMILY SSF48179 160 291 6.12E-40 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_00015 4d87c7f187b293e45c8e75fdce0b0c14 306 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 2 292 1.7E-106 T 12-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 TL08_08930 9d0259525d995e3e573a81e7997eb7de 282 Gene3D G3DSA:1.10.3720.10 17 271 2.3E-48 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08930 9d0259525d995e3e573a81e7997eb7de 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 263 8.9E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_08930 9d0259525d995e3e573a81e7997eb7de 282 SUPERFAMILY SSF161098 12 265 4.67E-52 T 12-10-2018 IPR035906 MetI-like superfamily TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 304 520 1.0E-47 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 151 297 2.5E-26 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 SUPERFAMILY SSF56601 147 530 1.41E-57 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 Gene3D G3DSA:3.40.710.10 318 528 4.7E-52 T 12-10-2018 TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 306 510 1.3E-41 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 414 428 9.3E-21 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 399 413 9.3E-21 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 175 194 9.3E-21 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 342 364 9.3E-21 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_01645 6412525d570fbfbcc32c1df815f476ae 533 Gene3D G3DSA:3.40.710.10 136 269 2.1E-10 T 12-10-2018 TL08_01750 f73ed88f58d12bb3c200047ee7213c07 337 SUPERFAMILY SSF56219 116 333 1.28E-27 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_01750 f73ed88f58d12bb3c200047ee7213c07 337 Gene3D G3DSA:3.60.10.10 115 337 2.6E-31 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_01750 f73ed88f58d12bb3c200047ee7213c07 337 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 129 326 2.5E-12 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TL08_01720 69d37d80edc709573890dd19556831f3 176 Pfam PF02261 Aspartate decarboxylase 1 114 2.9E-51 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TL08_01720 69d37d80edc709573890dd19556831f3 176 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 117 9.6E-51 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TL08_01720 69d37d80edc709573890dd19556831f3 176 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 72.1 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TL08_01720 69d37d80edc709573890dd19556831f3 176 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 2.0E-35 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TL08_01720 69d37d80edc709573890dd19556831f3 176 Gene3D G3DSA:2.40.40.20 1 123 7.0E-52 T 12-10-2018 TL08_01720 69d37d80edc709573890dd19556831f3 176 SUPERFAMILY SSF50692 1 116 1.37E-48 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TL08_11875 448dde7e0d8cd92d25e993c67cc42ece 523 SUPERFAMILY SSF109604 29 277 3.77E-45 T 12-10-2018 TL08_11875 448dde7e0d8cd92d25e993c67cc42ece 523 SMART SM00471 61 263 4.5E-10 T 12-10-2018 IPR003607 HD/PDEase domain TL08_11875 448dde7e0d8cd92d25e993c67cc42ece 523 Gene3D G3DSA:1.10.3210.10 2 511 1.8E-64 T 12-10-2018 TL08_11875 448dde7e0d8cd92d25e993c67cc42ece 523 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 29 509 8.8E-61 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 TL08_11875 448dde7e0d8cd92d25e993c67cc42ece 523 Pfam PF01966 HD domain 65 130 1.4E-9 T 12-10-2018 IPR006674 HD domain TL08_07495 bf6b7b2ed7d31fe8c765b6c783f1b0ea 100 Pfam PF01910 Thiamine-binding protein 3 93 7.0E-32 T 12-10-2018 IPR002767 Thiamine-binding protein TL08_07495 bf6b7b2ed7d31fe8c765b6c783f1b0ea 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 96 6.4E-18 T 12-10-2018 IPR002767 Thiamine-binding protein TL08_07495 bf6b7b2ed7d31fe8c765b6c783f1b0ea 100 SUPERFAMILY SSF89957 1 97 1.31E-29 T 12-10-2018 IPR029756 MTH1187/YkoF-like TL08_07495 bf6b7b2ed7d31fe8c765b6c783f1b0ea 100 Gene3D G3DSA:3.30.70.930 1 98 3.2E-29 T 12-10-2018 IPR029756 MTH1187/YkoF-like TL08_25330 5d1e0d4fe7eae9aab2ac9f029ff9dd8b 346 SMART SM00062 74 287 0.0039 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_25330 5d1e0d4fe7eae9aab2ac9f029ff9dd8b 346 Pfam PF09084 NMT1/THI5 like 73 279 5.3E-28 T 12-10-2018 IPR015168 SsuA/THI5-like TL08_25330 5d1e0d4fe7eae9aab2ac9f029ff9dd8b 346 SUPERFAMILY SSF53850 59 283 3.72E-41 T 12-10-2018 TL08_25330 5d1e0d4fe7eae9aab2ac9f029ff9dd8b 346 Gene3D G3DSA:3.40.190.10 171 344 1.7E-29 T 12-10-2018 TL08_25330 5d1e0d4fe7eae9aab2ac9f029ff9dd8b 346 Gene3D G3DSA:3.40.190.10 53 170 1.4E-16 T 12-10-2018 TL08_03685 a91ff9c1e4bc395f40a9127f5696684c 204 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 181 24.59 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TL08_03685 a91ff9c1e4bc395f40a9127f5696684c 204 Gene3D G3DSA:2.40.240.10 1 96 2.0E-25 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_03685 a91ff9c1e4bc395f40a9127f5696684c 204 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 177 2.9E-49 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TL08_03685 a91ff9c1e4bc395f40a9127f5696684c 204 Gene3D G3DSA:2.170.120.20 97 181 3.3E-14 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal TL08_03685 a91ff9c1e4bc395f40a9127f5696684c 204 Pfam PF01386 Ribosomal L25p family 6 93 5.4E-24 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TL08_03685 a91ff9c1e4bc395f40a9127f5696684c 204 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 8 92 2.0E-19 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TL08_03685 a91ff9c1e4bc395f40a9127f5696684c 204 SUPERFAMILY SSF50715 11 179 9.24E-48 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_03685 a91ff9c1e4bc395f40a9127f5696684c 204 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 101 179 6.8E-18 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain TL08_09815 2b87de30c93d7843892d89fb800b3194 471 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 34 462 6.2E-153 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 SUPERFAMILY SSF52540 35 198 2.69E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09815 2b87de30c93d7843892d89fb800b3194 471 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 260 275 4.5E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 231 4.5E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 Hamap MF_00195 GTPase Der [der]. 33 465 34.758 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 209 345 1.8E-22 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 34 159 1.7E-20 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 Gene3D G3DSA:3.40.50.300 208 379 6.5E-42 T 12-10-2018 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 Pfam PF01926 50S ribosome-binding GTPase 210 328 1.8E-20 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 Pfam PF01926 50S ribosome-binding GTPase 36 150 5.7E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 SUPERFAMILY SSF52540 168 465 1.36E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09815 2b87de30c93d7843892d89fb800b3194 471 SMART SM00382 32 168 1.1 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_09815 2b87de30c93d7843892d89fb800b3194 471 SMART SM00382 207 452 0.47 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_09815 2b87de30c93d7843892d89fb800b3194 471 PIRSF PIRSF006485 32 470 1.7E-158 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TL08_09815 2b87de30c93d7843892d89fb800b3194 471 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 384 462 4.1E-25 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like TL08_09815 2b87de30c93d7843892d89fb800b3194 471 Gene3D G3DSA:3.30.300.20 384 465 6.0E-25 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_09815 2b87de30c93d7843892d89fb800b3194 471 Gene3D G3DSA:3.40.50.300 31 192 7.8E-42 T 12-10-2018 TL08_13025 3f83611ccb17d0df9389dcae790039db 291 Gene3D G3DSA:1.10.3720.10 79 273 8.9E-29 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13025 3f83611ccb17d0df9389dcae790039db 291 SUPERFAMILY SSF161098 83 265 9.03E-34 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13025 3f83611ccb17d0df9389dcae790039db 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 269 2.0E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF08990 Erythronolide synthase docking 2 25 1.1E-11 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2145 2160 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:1.10.1200.10 2100 2192 2.9E-35 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF51735 1831 2087 9.24E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF50129 1533 1650 2.67E-25 T 12-10-2018 IPR011032 GroES-like superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.90.180.10 1502 1827 1.3E-109 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF51735 1286 1491 3.23E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00823 Phosphopantetheine attachment site 3928 4000 1.3E-28 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00823 Phosphopantetheine attachment site 2118 2190 4.4E-34 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2585 2705 5.5E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 532 1.5E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:1.10.1200.10 3908 4001 5.7E-30 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2217 2457 9.2E-80 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 283 2.6E-83 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM01294 2119 2186 9.9E-7 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.40.50.720 3436 3901 8.4E-120 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF47336 2112 2230 1.96E-24 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 572 921 2.0E-109 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2743 3085 4.5E-111 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00825 Beta-ketoacyl synthase 2218 2635 1.3E-207 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00825 Beta-ketoacyl synthase 36 461 9.6E-214 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.40.50.11460 1287 1491 3.6E-34 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF51735 1616 1750 2.45E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF53901 2213 2579 9.7E-100 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF55048 711 785 2.35E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.30.70.3290 2655 3132 4.2E-152 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.40.366.10 570 924 9.5E-148 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.40.50.720 1828 2086 3.0E-64 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.30.70.3290 482 968 9.5E-148 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF47336 3924 4007 2.49E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF08659 KR domain 3644 3822 2.6E-58 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF08659 KR domain 1834 2011 2.9E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF51735 3433 3625 3.31E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.40.366.10 2741 3088 4.2E-152 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00829 1517 1823 1.5E-151 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2465 2582 2.1E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 1.3E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF14765 Polyketide synthase dehydratase 3151 3423 5.5E-58 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF14765 Polyketide synthase dehydratase 987 1277 2.1E-50 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF00550 Phosphopantetheine attachment site 3931 3996 4.7E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF00550 Phosphopantetheine attachment site 2120 2186 9.1E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF51735 3638 3880 2.02E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3955 3970 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF00107 Zinc-binding dehydrogenase 1656 1747 5.7E-19 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2370 2386 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF53901 31 405 1.17E-98 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00826 987 1154 8.0E-59 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00826 3151 3314 1.1E-66 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.10.129.110 976 1284 3.0E-94 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.10.129.110 3140 3429 1.0E-100 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF52151 2739 3056 8.89E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1537 1593 8.0E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF00698 Acyl transferase domain 2743 3103 2.5E-52 T 12-10-2018 IPR014043 Acyl transferase TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Pfam PF00698 Acyl transferase domain 572 879 2.0E-53 T 12-10-2018 IPR014043 Acyl transferase TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.40.47.10 2203 2635 1.3E-179 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 Gene3D G3DSA:3.40.47.10 16 460 4.3E-183 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF55048 2881 2961 2.75E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SUPERFAMILY SSF52151 568 880 1.23E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3644 3824 1.5E-56 T 12-10-2018 TL08_15875 81ebdb1d62d0db7f9cf2b442c1b2665b 4080 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1833 2013 5.4E-52 T 12-10-2018 TL08_25180 7a7b438ba7416d05c60d1dd8967e8237 295 Gene3D G3DSA:3.40.1280.10 129 285 1.5E-44 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TL08_25180 7a7b438ba7416d05c60d1dd8967e8237 295 Pfam PF00588 SpoU rRNA Methylase family 141 280 1.9E-29 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TL08_25180 7a7b438ba7416d05c60d1dd8967e8237 295 SUPERFAMILY SSF75217 117 283 1.44E-37 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TL08_25180 7a7b438ba7416d05c60d1dd8967e8237 295 SUPERFAMILY SSF55315 25 124 6.36E-12 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_15025 703db610bf85f4d5a119b12ee71850ce 697 SUPERFAMILY SSF52317 405 614 1.48E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_15025 703db610bf85f4d5a119b12ee71850ce 697 Pfam PF08532 Beta-galactosidase trimerisation domain 407 613 1.8E-65 T 12-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_15025 703db610bf85f4d5a119b12ee71850ce 697 Pfam PF02449 Beta-galactosidase 25 393 1.4E-149 T 12-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_15025 703db610bf85f4d5a119b12ee71850ce 697 SUPERFAMILY SSF51445 18 377 7.16E-110 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_15025 703db610bf85f4d5a119b12ee71850ce 697 Gene3D G3DSA:3.40.50.880 405 618 3.2E-64 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_15025 703db610bf85f4d5a119b12ee71850ce 697 Pfam PF08533 Beta-galactosidase C-terminal domain 625 688 9.7E-7 T 12-10-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_15025 703db610bf85f4d5a119b12ee71850ce 697 PIRSF PIRSF001084 13 689 4.5E-263 T 12-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_15025 703db610bf85f4d5a119b12ee71850ce 697 Gene3D G3DSA:3.20.20.80 3 399 9.5E-138 T 12-10-2018 TL08_16300 813fcd935a99ea3805034f129a774324 401 PRINTS PR00359 B-class P450 signature 85 96 6.3E-39 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 PRINTS PR00359 B-class P450 signature 180 202 6.3E-39 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 PRINTS PR00359 B-class P450 signature 278 305 6.3E-39 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 PRINTS PR00359 B-class P450 signature 131 147 6.3E-39 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 PRINTS PR00359 B-class P450 signature 336 347 6.3E-39 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 PRINTS PR00359 B-class P450 signature 306 321 6.3E-39 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 PRINTS PR00359 B-class P450 signature 261 272 6.3E-39 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 PRINTS PR00359 B-class P450 signature 327 336 6.3E-39 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 Gene3D G3DSA:1.10.630.10 1 398 5.3E-138 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 329 338 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 SUPERFAMILY SSF48264 12 386 2.49E-81 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16300 813fcd935a99ea3805034f129a774324 401 Pfam PF00067 Cytochrome P450 193 350 1.5E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18375 6b9eb0463925636b54f97430d42a9184 322 Pfam PF13280 WYL domain 140 316 8.6E-34 T 12-10-2018 IPR026881 WYL domain TL08_18375 6b9eb0463925636b54f97430d42a9184 322 Pfam PF08279 HTH domain 9 60 3.7E-15 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TL08_18375 6b9eb0463925636b54f97430d42a9184 322 Gene3D G3DSA:1.10.10.10 1 64 9.6E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18375 6b9eb0463925636b54f97430d42a9184 322 SUPERFAMILY SSF46785 4 63 4.72E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_18375 6b9eb0463925636b54f97430d42a9184 322 PIRSF PIRSF016838 67 322 4.0E-10 T 12-10-2018 IPR028349 Protein PafC TL08_18375 6b9eb0463925636b54f97430d42a9184 322 PIRSF PIRSF016838 1 53 1.0E-4 T 12-10-2018 IPR028349 Protein PafC TL08_25260 5ccf41bd7b7bae49948f09345f7b18f3 165 Gene3D G3DSA:2.40.50.100 96 159 1.6E-14 T 12-10-2018 TL08_25260 5ccf41bd7b7bae49948f09345f7b18f3 165 Gene3D G3DSA:1.10.1660.10 33 79 5.0E-7 T 12-10-2018 TL08_25260 5ccf41bd7b7bae49948f09345f7b18f3 165 Pfam PF03459 TOBE domain 98 157 3.5E-7 T 12-10-2018 IPR005116 Transport-associated OB, type 1 TL08_25260 5ccf41bd7b7bae49948f09345f7b18f3 165 SUPERFAMILY SSF50331 42 159 2.43E-16 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TL08_23955 69ab6c998ac23b424723b999a47e2dc2 255 PIRSF PIRSF006648 1 254 8.2E-20 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_23955 69ab6c998ac23b424723b999a47e2dc2 255 Pfam PF01061 ABC-2 type transporter 15 221 6.1E-17 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 SUPERFAMILY SSF46894 3 88 7.09E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 SMART SM00862 16 88 1.1E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 Gene3D G3DSA:3.40.50.300 256 388 1.2E-7 T 12-10-2018 TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 SUPERFAMILY SSF48452 92 255 1.27E-38 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 Gene3D G3DSA:1.10.10.10 1 91 1.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 SMART SM01043 93 238 1.3E-45 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 Gene3D G3DSA:1.25.40.10 609 863 2.0E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 SUPERFAMILY SSF52540 258 500 1.12E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 Pfam PF03704 Bacterial transcriptional activator domain 93 238 4.3E-36 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 Gene3D G3DSA:1.25.40.10 92 255 1.3E-45 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05180 5eeb3de767a2f1e83533c7931c72e99f 894 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 76 6.0E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_01435 e72ad2ea56e95fbf8a56df08e6430dde 616 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 65 405 5.6E-106 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_01435 e72ad2ea56e95fbf8a56df08e6430dde 616 Gene3D G3DSA:3.20.20.300 48 426 1.4E-125 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 TL08_01435 e72ad2ea56e95fbf8a56df08e6430dde 616 SUPERFAMILY SSF52279 444 613 1.57E-15 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 TL08_01435 e72ad2ea56e95fbf8a56df08e6430dde 616 Gene3D G3DSA:3.40.50.1700 428 614 1.2E-31 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 TL08_01435 e72ad2ea56e95fbf8a56df08e6430dde 616 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 444 612 2.1E-13 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TL08_01435 e72ad2ea56e95fbf8a56df08e6430dde 616 SUPERFAMILY SSF51445 49 438 4.53E-102 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_02200 d326a0f4b87266d55aa834de5f1ccbac 186 SUPERFAMILY SSF55826 39 177 8.37E-20 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TL08_02200 d326a0f4b87266d55aa834de5f1ccbac 186 Gene3D G3DSA:3.90.960.10 30 179 2.7E-20 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TL08_02200 d326a0f4b87266d55aa834de5f1ccbac 186 Pfam PF04073 Aminoacyl-tRNA editing domain 48 167 4.7E-15 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TL08_25540 607db62b9d22c5b1ae1b6210b02f62d5 543 Gene3D G3DSA:3.40.50.720 331 512 4.6E-13 T 12-10-2018 TL08_25540 607db62b9d22c5b1ae1b6210b02f62d5 543 SUPERFAMILY SSF51735 198 504 8.38E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_25540 607db62b9d22c5b1ae1b6210b02f62d5 543 Pfam PF00106 short chain dehydrogenase 204 291 2.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_25540 607db62b9d22c5b1ae1b6210b02f62d5 543 Gene3D G3DSA:3.40.50.720 190 304 5.9E-17 T 12-10-2018 TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 SMART SM00052 514 762 6.5E-35 T 12-10-2018 IPR001633 EAL domain TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 Pfam PF00989 PAS fold 218 328 1.1E-9 T 12-10-2018 IPR013767 PAS fold GO:0006355 TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 Pfam PF00563 EAL domain 523 757 1.9E-41 T 12-10-2018 IPR001633 EAL domain TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 342 501 8.5E-25 T 12-10-2018 IPR000160 GGDEF domain TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 SMART SM00267 332 504 1.2E-32 T 12-10-2018 IPR000160 GGDEF domain TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 SUPERFAMILY SSF55785 204 330 1.35E-21 T 12-10-2018 IPR035965 PAS domain superfamily TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 Pfam PF00990 Diguanylate cyclase, GGDEF domain 345 499 9.5E-30 T 12-10-2018 IPR000160 GGDEF domain TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 SMART SM00091 217 283 5.3E-12 T 12-10-2018 IPR000014 PAS domain TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 SUPERFAMILY SSF141868 523 769 2.75E-42 T 12-10-2018 IPR035919 EAL domain superfamily TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 213 336 2.0E-13 T 12-10-2018 IPR000014 PAS domain TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 Gene3D G3DSA:3.30.450.20 203 330 1.0E-19 T 12-10-2018 TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 Gene3D G3DSA:3.30.70.270 332 506 5.4E-38 T 12-10-2018 TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 Gene3D G3DSA:3.20.20.450 515 769 3.8E-53 T 12-10-2018 IPR035919 EAL domain superfamily TL08_25020 03dc4c1bde04b5fd68a1a76daf4e8e8e 776 SUPERFAMILY SSF55073 348 506 2.2E-33 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_04355 52b3974fb4e026159912215612101fdb 240 SUPERFAMILY SSF52172 10 183 7.7E-21 T 12-10-2018 IPR011006 CheY-like superfamily TL08_04355 52b3974fb4e026159912215612101fdb 240 SMART SM00421 159 221 2.4E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_04355 52b3974fb4e026159912215612101fdb 240 Gene3D G3DSA:1.10.10.10 114 233 1.7E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04355 52b3974fb4e026159912215612101fdb 240 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 206 4.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_04355 52b3974fb4e026159912215612101fdb 240 Pfam PF00072 Response regulator receiver domain 14 110 9.4E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_04355 52b3974fb4e026159912215612101fdb 240 SMART SM00448 12 131 3.3E-10 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_04355 52b3974fb4e026159912215612101fdb 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 6.1E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_04355 52b3974fb4e026159912215612101fdb 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 6.1E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_04355 52b3974fb4e026159912215612101fdb 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 6.1E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_04355 52b3974fb4e026159912215612101fdb 240 Gene3D G3DSA:3.40.50.2300 12 110 1.6E-14 T 12-10-2018 TL08_10670 ae49b874e35353ab143addefdec5f67f 262 Gene3D G3DSA:1.10.357.10 99 258 3.1E-33 T 12-10-2018 TL08_10670 ae49b874e35353ab143addefdec5f67f 262 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 88 8.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10670 ae49b874e35353ab143addefdec5f67f 262 SUPERFAMILY SSF48498 107 258 6.67E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_10670 ae49b874e35353ab143addefdec5f67f 262 Gene3D G3DSA:1.10.10.60 21 95 3.9E-24 T 12-10-2018 TL08_10670 ae49b874e35353ab143addefdec5f67f 262 SUPERFAMILY SSF46689 34 101 6.48E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_10670 ae49b874e35353ab143addefdec5f67f 262 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 104 255 8.9E-12 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 SUPERFAMILY SSF46894 153 224 2.18E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 SMART SM00448 5 120 1.2E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 217 7.7E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 Gene3D G3DSA:3.40.50.12740 5 223 3.7E-66 T 12-10-2018 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 SUPERFAMILY SSF52172 4 138 8.82E-31 T 12-10-2018 IPR011006 CheY-like superfamily TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 SMART SM00421 160 217 6.5E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 4.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 4.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 4.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05220 0db328f9ea1d5451775e0336e336fa73 227 Pfam PF00072 Response regulator receiver domain 8 120 3.2E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 SUPERFAMILY SSF55785 180 291 1.44E-6 T 12-10-2018 IPR035965 PAS domain superfamily TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 Pfam PF12282 Signal transduction histidine kinase 4 151 3.4E-54 T 12-10-2018 IPR022066 Signal transduction histidine kinase, N-terminal TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 SMART SM00387 394 494 6.5E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 SUPERFAMILY SSF55874 355 493 8.25E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 Pfam PF08448 PAS fold 178 286 5.6E-6 T 12-10-2018 IPR013656 PAS fold-4 TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 Gene3D G3DSA:3.30.450.280 1 136 1.8E-43 T 12-10-2018 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 Pfam PF07568 Histidine kinase 300 368 9.8E-23 T 12-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 Gene3D G3DSA:3.30.565.10 356 496 2.0E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 Pfam PF13581 Histidine kinase-like ATPase domain 389 468 6.1E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_23175 3bd566ef152240a7c2a875ff7e0fb814 496 Gene3D G3DSA:3.30.450.20 137 286 8.9E-41 T 12-10-2018 TL08_07475 1c0601db239cc5aca3577593bd7ff442 320 SMART SM00382 49 306 0.0016 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_07475 1c0601db239cc5aca3577593bd7ff442 320 Pfam PF03308 ArgK protein 22 282 5.2E-98 T 12-10-2018 TL08_07475 1c0601db239cc5aca3577593bd7ff442 320 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 315 3.0E-102 T 12-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TL08_07475 1c0601db239cc5aca3577593bd7ff442 320 Gene3D G3DSA:3.40.50.300 46 255 4.2E-85 T 12-10-2018 TL08_07475 1c0601db239cc5aca3577593bd7ff442 320 SUPERFAMILY SSF52540 4 283 1.6E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 SMART SM00663 310 589 6.3E-172 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Gene3D G3DSA:1.10.274.100 565 717 1.1E-40 T 12-10-2018 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Gene3D G3DSA:1.10.40.90 449 491 1.8E-23 T 12-10-2018 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 SUPERFAMILY SSF64484 5 1254 0.0 T 12-10-2018 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Gene3D G3DSA:1.10.132.30 718 852 2.3E-49 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Pfam PF05000 RNA polymerase Rpb1, domain 4 753 820 7.4E-8 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1253 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 3.1E-80 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 461 3.5E-8 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 467 560 2.3E-28 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Pfam PF04998 RNA polymerase Rpb1, domain 5 828 1201 2.5E-64 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Gene3D G3DSA:1.10.1790.20 1011 1200 2.8E-62 T 12-10-2018 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 721 1.0E-26 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Gene3D G3DSA:2.40.50.100 1027 1101 2.8E-62 T 12-10-2018 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1263 17.467 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TL08_02910 28e420b647bf90a8657a5dc0cd72ab75 1303 Gene3D G3DSA:1.10.150.390 1202 1265 2.2E-29 T 12-10-2018 TL08_01220 8a61a7357d175a3327798a536e6f08e8 392 Pfam PF02374 Anion-transporting ATPase 32 350 5.3E-24 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 TL08_01220 8a61a7357d175a3327798a536e6f08e8 392 SUPERFAMILY SSF52540 28 322 8.8E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03025 c5d88844e02fbca46592d8b299cf63a7 84 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 8.7E-21 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03025 c5d88844e02fbca46592d8b299cf63a7 84 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 17.434 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03025 c5d88844e02fbca46592d8b299cf63a7 84 Gene3D G3DSA:1.10.287.310 6 69 1.3E-26 T 12-10-2018 TL08_03025 c5d88844e02fbca46592d8b299cf63a7 84 SUPERFAMILY SSF46561 6 67 1.07E-22 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03025 c5d88844e02fbca46592d8b299cf63a7 84 Pfam PF00831 Ribosomal L29 protein 8 64 6.4E-25 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03025 c5d88844e02fbca46592d8b299cf63a7 84 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 12-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_08720 6ff2145be15b1f01418c1ad83b9b4db5 182 SUPERFAMILY SSF52540 8 152 1.05E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08720 6ff2145be15b1f01418c1ad83b9b4db5 182 Pfam PF01202 Shikimate kinase 17 127 2.7E-9 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TL08_08720 6ff2145be15b1f01418c1ad83b9b4db5 182 Gene3D G3DSA:3.40.50.300 7 178 9.1E-63 T 12-10-2018 TL08_08720 6ff2145be15b1f01418c1ad83b9b4db5 182 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 11 169 7.6E-57 T 12-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 TL08_20120 43897b5569caa93e64cfb09fe18f0994 270 SUPERFAMILY SSF53335 13 252 9.2E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_20120 43897b5569caa93e64cfb09fe18f0994 270 Pfam PF04672 S-adenosyl methyltransferase 11 268 4.9E-79 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_20120 43897b5569caa93e64cfb09fe18f0994 270 PIRSF PIRSF017393 1 269 1.0E-87 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_20120 43897b5569caa93e64cfb09fe18f0994 270 Gene3D G3DSA:3.40.50.150 2 268 3.1E-96 T 12-10-2018 TL08_25165 5c91eae42fcdf41bbfd4fb5b7f66c64e 707 ProSitePatterns PS00211 ABC transporters family signature. 555 569 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_25165 5c91eae42fcdf41bbfd4fb5b7f66c64e 707 SUPERFAMILY SSF52540 393 651 9.25E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25165 5c91eae42fcdf41bbfd4fb5b7f66c64e 707 Gene3D G3DSA:3.40.50.300 391 662 4.7E-79 T 12-10-2018 TL08_25165 5c91eae42fcdf41bbfd4fb5b7f66c64e 707 Pfam PF00664 ABC transporter transmembrane region 77 347 9.7E-39 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_25165 5c91eae42fcdf41bbfd4fb5b7f66c64e 707 Pfam PF00005 ABC transporter 434 582 6.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_25165 5c91eae42fcdf41bbfd4fb5b7f66c64e 707 SUPERFAMILY SSF90123 65 372 8.5E-68 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_25165 5c91eae42fcdf41bbfd4fb5b7f66c64e 707 Gene3D G3DSA:1.20.1560.10 46 381 2.2E-69 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_25165 5c91eae42fcdf41bbfd4fb5b7f66c64e 707 SMART SM00382 443 629 1.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_16865 a197ac26beee07f6922f3f4d785d5891 518 Pfam PF02384 N-6 DNA Methylase 138 435 2.0E-67 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TL08_16865 a197ac26beee07f6922f3f4d785d5891 518 Gene3D G3DSA:3.40.50.150 138 475 1.1E-80 T 12-10-2018 TL08_16865 a197ac26beee07f6922f3f4d785d5891 518 Pfam PF12161 HsdM N-terminal domain 16 124 1.7E-11 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain TL08_16865 a197ac26beee07f6922f3f4d785d5891 518 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 185 199 1.1E-20 T 12-10-2018 TL08_16865 a197ac26beee07f6922f3f4d785d5891 518 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 161 177 1.1E-20 T 12-10-2018 TL08_16865 a197ac26beee07f6922f3f4d785d5891 518 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 269 281 1.1E-20 T 12-10-2018 TL08_16865 a197ac26beee07f6922f3f4d785d5891 518 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 311 335 1.1E-20 T 12-10-2018 TL08_16865 a197ac26beee07f6922f3f4d785d5891 518 Gene3D G3DSA:1.20.1260.30 7 136 2.0E-34 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily TL08_16865 a197ac26beee07f6922f3f4d785d5891 518 SUPERFAMILY SSF53335 15 505 2.64E-113 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_15405 2cabeb9e1a14a856f58cd27dc8601c42 253 Pfam PF01061 ABC-2 type transporter 19 216 1.4E-26 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_15405 2cabeb9e1a14a856f58cd27dc8601c42 253 PIRSF PIRSF006648 2 253 3.1E-45 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_03435 9be0b6354a6f6aa6f3a7b48b1ecfdbb8 311 Pfam PF00248 Aldo/keto reductase family 15 302 4.5E-52 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_03435 9be0b6354a6f6aa6f3a7b48b1ecfdbb8 311 Gene3D G3DSA:3.20.20.100 1 311 1.1E-80 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_03435 9be0b6354a6f6aa6f3a7b48b1ecfdbb8 311 SUPERFAMILY SSF51430 2 305 1.57E-70 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_21360 9b4012708cf838216102f187828d5dab 302 Gene3D G3DSA:3.30.300.20 189 302 8.7E-41 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_21360 9b4012708cf838216102f187828d5dab 302 Hamap MF_00367 GTPase Era [era]. 8 302 34.358 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_21360 9b4012708cf838216102f187828d5dab 302 SUPERFAMILY SSF52540 14 218 1.48E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21360 9b4012708cf838216102f187828d5dab 302 Pfam PF01926 50S ribosome-binding GTPase 13 129 1.5E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_21360 9b4012708cf838216102f187828d5dab 302 TIGRFAM TIGR00436 era: GTP-binding protein Era 11 285 1.9E-67 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_21360 9b4012708cf838216102f187828d5dab 302 Pfam PF07650 KH domain 212 291 3.9E-17 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_21360 9b4012708cf838216102f187828d5dab 302 SUPERFAMILY SSF54814 187 302 6.15E-35 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TL08_21360 9b4012708cf838216102f187828d5dab 302 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 172 3.3E-17 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TL08_21360 9b4012708cf838216102f187828d5dab 302 Gene3D G3DSA:3.40.50.300 6 187 2.6E-42 T 12-10-2018 TL08_23090 d427ee04f5ef350020f5cddddd6a16ec 275 Gene3D G3DSA:2.40.440.10 133 275 5.0E-18 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TL08_23090 d427ee04f5ef350020f5cddddd6a16ec 275 SUPERFAMILY SSF141523 155 274 2.35E-16 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TL08_23090 d427ee04f5ef350020f5cddddd6a16ec 275 Pfam PF03734 L,D-transpeptidase catalytic domain 158 274 1.5E-11 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 TL08_18855 950f31d6dcec2498511919b84350da28 345 Gene3D G3DSA:2.160.20.10 46 343 2.7E-77 T 12-10-2018 IPR012334 Pectin lyase fold TL08_18855 950f31d6dcec2498511919b84350da28 345 SUPERFAMILY SSF51126 48 339 1.56E-61 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_18855 950f31d6dcec2498511919b84350da28 345 Pfam PF00544 Pectate lyase 106 270 2.4E-19 T 12-10-2018 IPR002022 Pectate lyase TL08_18855 950f31d6dcec2498511919b84350da28 345 SMART SM00656 68 283 2.8E-11 T 12-10-2018 IPR002022 Pectate lyase TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 383 4.7E-96 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 130 5.0E-31 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 Gene3D G3DSA:3.10.150.10 261 385 3.1E-44 T 12-10-2018 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 258 369 1.1E-32 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 Pfam PF02767 DNA polymerase III beta subunit, central domain 142 256 3.4E-32 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 Gene3D G3DSA:3.10.150.10 136 260 5.8E-34 T 12-10-2018 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 SUPERFAMILY SSF55979 1 130 6.67E-21 T 12-10-2018 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 SUPERFAMILY SSF55979 142 257 1.47E-20 T 12-10-2018 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 SMART SM00480 17 379 5.0E-124 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 PIRSF PIRSF000804 1 384 3.9E-100 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 SUPERFAMILY SSF55979 258 383 4.19E-31 T 12-10-2018 TL08_00010 a4d2129b190dde71f5ada0175cbecca9 385 Gene3D G3DSA:3.10.150.10 1 133 4.4E-42 T 12-10-2018 TL08_10695 8960653e491682839012e126e1810d26 361 SUPERFAMILY SSF50129 310 360 1.22E-7 T 12-10-2018 IPR011032 GroES-like superfamily TL08_10695 8960653e491682839012e126e1810d26 361 Gene3D G3DSA:3.90.180.10 9 358 6.4E-116 T 12-10-2018 TL08_10695 8960653e491682839012e126e1810d26 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 1.4E-203 T 12-10-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase MetaCyc: PWY-7908 TL08_10695 8960653e491682839012e126e1810d26 361 SUPERFAMILY SSF51735 156 326 3.54E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_10695 8960653e491682839012e126e1810d26 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 1.6E-27 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_10695 8960653e491682839012e126e1810d26 361 SUPERFAMILY SSF50129 3 186 3.65E-54 T 12-10-2018 IPR011032 GroES-like superfamily TL08_10695 8960653e491682839012e126e1810d26 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_10695 8960653e491682839012e126e1810d26 361 Pfam PF00107 Zinc-binding dehydrogenase 190 320 1.1E-29 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_10695 8960653e491682839012e126e1810d26 361 SMART SM00829 12 361 8.1E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_10695 8960653e491682839012e126e1810d26 361 Gene3D G3DSA:3.40.50.720 167 304 6.4E-116 T 12-10-2018 TL08_05685 4b4ec818f054f130c035a5c4de3b40cc 174 Pfam PF07977 FabA-like domain 38 157 2.8E-21 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TL08_05685 4b4ec818f054f130c035a5c4de3b40cc 174 SUPERFAMILY SSF54637 31 161 1.71E-34 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_05685 4b4ec818f054f130c035a5c4de3b40cc 174 Gene3D G3DSA:3.10.129.10 23 164 3.1E-44 T 12-10-2018 TL08_00860 ffbc2d7a2ce5835156fbcc7718a3ec16 218 SUPERFAMILY SSF52218 1 213 2.48E-30 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_00860 ffbc2d7a2ce5835156fbcc7718a3ec16 218 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 211 19.883 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 TL08_00860 ffbc2d7a2ce5835156fbcc7718a3ec16 218 Gene3D G3DSA:3.40.50.360 1 213 1.3E-34 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_00860 ffbc2d7a2ce5835156fbcc7718a3ec16 218 Pfam PF02525 Flavodoxin-like fold 1 161 7.8E-24 T 12-10-2018 IPR003680 Flavodoxin-like fold TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 Gene3D G3DSA:1.20.1640.10 506 1007 4.0E-287 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 1.8E-42 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 1.8E-42 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 1.8E-42 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 1.8E-42 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.8E-42 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 1.8E-42 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 Gene3D G3DSA:3.30.70.1320 132 323 4.0E-287 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 Gene3D G3DSA:1.20.1640.10 12 505 4.0E-287 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 SUPERFAMILY SSF82866 789 1013 1.83E-49 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 Gene3D G3DSA:3.30.70.1430 558 655 4.0E-287 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 Pfam PF00873 AcrB/AcrD/AcrF family 5 1009 3.6E-230 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 Gene3D G3DSA:3.30.2090.10 705 792 4.0E-287 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 SUPERFAMILY SSF82693 135 320 2.72E-11 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 SUPERFAMILY SSF82714 706 789 3.66E-11 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 Gene3D G3DSA:3.30.70.1430 41 800 4.0E-287 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 SUPERFAMILY SSF82693 558 647 5.23E-7 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 Gene3D G3DSA:3.30.70.1440 656 849 4.0E-287 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 Gene3D G3DSA:3.30.2090.10 177 266 4.0E-287 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 SUPERFAMILY SSF82693 42 129 1.99E-21 T 12-10-2018 TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 SUPERFAMILY SSF82714 182 262 1.2E-11 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TL08_17630 8d705c1d2b860d01cce13b138bdfefc7 1035 SUPERFAMILY SSF82866 289 488 1.57E-45 T 12-10-2018 TL08_21285 bdfa9cb6950d10d6c353e9e2221268df 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 81 96 6.1E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21285 bdfa9cb6950d10d6c353e9e2221268df 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 79 6.1E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21285 bdfa9cb6950d10d6c353e9e2221268df 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 6.1E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21285 bdfa9cb6950d10d6c353e9e2221268df 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 96 111 6.1E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21285 bdfa9cb6950d10d6c353e9e2221268df 138 SMART SM00418 47 125 3.3E-28 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21285 bdfa9cb6950d10d6c353e9e2221268df 138 Gene3D G3DSA:1.10.10.10 35 136 2.8E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21285 bdfa9cb6950d10d6c353e9e2221268df 138 Pfam PF01022 Bacterial regulatory protein, arsR family 55 98 2.7E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21285 bdfa9cb6950d10d6c353e9e2221268df 138 SUPERFAMILY SSF46785 36 120 1.34E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_26780 406ed990dafc2108e3e565fd571767f8 209 SUPERFAMILY SSF51735 5 196 7.82E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_26780 406ed990dafc2108e3e565fd571767f8 209 Gene3D G3DSA:3.40.50.720 1 208 6.8E-53 T 12-10-2018 TL08_26780 406ed990dafc2108e3e565fd571767f8 209 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 143 1.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26780 406ed990dafc2108e3e565fd571767f8 209 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 52 63 1.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26780 406ed990dafc2108e3e565fd571767f8 209 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 104 112 1.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26780 406ed990dafc2108e3e565fd571767f8 209 Pfam PF00106 short chain dehydrogenase 9 169 6.3E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26780 406ed990dafc2108e3e565fd571767f8 209 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 52 63 2.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26780 406ed990dafc2108e3e565fd571767f8 209 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 143 2.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26780 406ed990dafc2108e3e565fd571767f8 209 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 162 2.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26780 406ed990dafc2108e3e565fd571767f8 209 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 114 2.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26780 406ed990dafc2108e3e565fd571767f8 209 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 111 139 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_16635 e2816199ba6dafbc7a4d799a473e90c2 255 SUPERFAMILY SSF53474 22 237 2.53E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16635 e2816199ba6dafbc7a4d799a473e90c2 255 Gene3D G3DSA:3.40.50.1820 20 237 7.8E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10610 55c128a6b71d6a467c39aae0683d1358 291 Pfam PF00296 Luciferase-like monooxygenase 2 231 8.9E-36 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_10610 55c128a6b71d6a467c39aae0683d1358 291 Gene3D G3DSA:3.20.20.30 1 274 1.6E-61 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_10610 55c128a6b71d6a467c39aae0683d1358 291 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 10 234 1.5E-90 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c TL08_10610 55c128a6b71d6a467c39aae0683d1358 291 SUPERFAMILY SSF51679 1 289 4.86E-53 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_26605 07f11b9b3798a964a0e457e37f4ac17e 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 18 190 2.1E-22 T 12-10-2018 TL08_26605 07f11b9b3798a964a0e457e37f4ac17e 232 Gene3D G3DSA:3.40.50.1000 16 211 6.5E-50 T 12-10-2018 IPR023214 HAD superfamily TL08_26605 07f11b9b3798a964a0e457e37f4ac17e 232 Gene3D G3DSA:1.10.150.240 30 91 6.5E-50 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TL08_26605 07f11b9b3798a964a0e457e37f4ac17e 232 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 17 190 7.2E-18 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_26605 07f11b9b3798a964a0e457e37f4ac17e 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 15 26 3.0E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_26605 07f11b9b3798a964a0e457e37f4ac17e 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 150 3.0E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_26605 07f11b9b3798a964a0e457e37f4ac17e 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 3.0E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_26605 07f11b9b3798a964a0e457e37f4ac17e 232 SUPERFAMILY SSF56784 15 211 6.2E-45 T 12-10-2018 IPR036412 HAD-like superfamily TL08_00810 0e14693ea1ab04949fdb8bf99bbfcdd1 222 SUPERFAMILY SSF159275 27 222 8.76E-42 T 12-10-2018 TL08_00810 0e14693ea1ab04949fdb8bf99bbfcdd1 222 Pfam PF06475 Putative glycolipid-binding 29 221 3.1E-44 T 12-10-2018 IPR009467 Putative glycolipid-binding protein TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 Gene3D G3DSA:1.10.8.60 316 424 6.9E-39 T 12-10-2018 TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 2.1E-194 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 SMART SM00382 113 266 3.7E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 Gene3D G3DSA:3.30.50.30 3 50 5.5E-24 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 SUPERFAMILY SSF52540 59 405 5.29E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 310 1.5E-49 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.32 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 SUPERFAMILY SSF57716 11 46 1.37E-11 T 12-10-2018 TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 5.6E-16 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 SMART SM00994 10 49 1.1E-23 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 SMART SM01086 317 411 5.9E-32 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TL08_08060 c92665675a1bb8352270cf4a65b21df4 426 Gene3D G3DSA:3.40.50.300 54 314 1.1E-106 T 12-10-2018 TL08_20730 9ea7678fe588cd4804b3f3708d9ef859 91 SUPERFAMILY SSF46894 21 91 4.08E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_20730 9ea7678fe588cd4804b3f3708d9ef859 91 SMART SM00421 28 85 1.4E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20730 9ea7678fe588cd4804b3f3708d9ef859 91 Gene3D G3DSA:1.10.10.10 18 91 1.6E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_20730 9ea7678fe588cd4804b3f3708d9ef859 91 Pfam PF00196 Bacterial regulatory proteins, luxR family 30 85 6.5E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_10150 ca818bcc507f0b18e27a77483e680c6c 604 Gene3D G3DSA:3.40.50.300 206 482 3.9E-39 T 12-10-2018 TL08_10150 ca818bcc507f0b18e27a77483e680c6c 604 Pfam PF01580 FtsK/SpoIIIE family 250 331 1.5E-8 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TL08_10150 ca818bcc507f0b18e27a77483e680c6c 604 SUPERFAMILY SSF52540 228 469 2.72E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06460 d0d2b9103211e472f3bd3879ead2881e 352 Pfam PF00107 Zinc-binding dehydrogenase 183 312 2.6E-24 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_06460 d0d2b9103211e472f3bd3879ead2881e 352 SMART SM00829 10 347 3.9E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_06460 d0d2b9103211e472f3bd3879ead2881e 352 SUPERFAMILY SSF50129 1 179 1.14E-36 T 12-10-2018 IPR011032 GroES-like superfamily TL08_06460 d0d2b9103211e472f3bd3879ead2881e 352 Gene3D G3DSA:3.40.50.720 159 320 1.4E-111 T 12-10-2018 TL08_06460 d0d2b9103211e472f3bd3879ead2881e 352 Gene3D G3DSA:3.90.180.10 7 346 1.4E-111 T 12-10-2018 TL08_06460 d0d2b9103211e472f3bd3879ead2881e 352 SUPERFAMILY SSF51735 150 323 4.67E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_06460 d0d2b9103211e472f3bd3879ead2881e 352 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 141 8.1E-13 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_19450 e479a93151844f84687aafd2fe097c40 326 PRINTS PR00139 Asparaginase/glutaminase family signature 78 96 6.2E-11 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TL08_19450 e479a93151844f84687aafd2fe097c40 326 PRINTS PR00139 Asparaginase/glutaminase family signature 257 275 6.2E-11 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TL08_19450 e479a93151844f84687aafd2fe097c40 326 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 6.2E-11 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TL08_19450 e479a93151844f84687aafd2fe097c40 326 Gene3D G3DSA:3.40.50.1170 1 206 2.9E-38 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 TL08_19450 e479a93151844f84687aafd2fe097c40 326 Pfam PF00710 Asparaginase, N-terminal 3 192 3.5E-34 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 TL08_19450 e479a93151844f84687aafd2fe097c40 326 PIRSF PIRSF500176 1 326 5.6E-50 T 12-10-2018 TL08_19450 e479a93151844f84687aafd2fe097c40 326 SUPERFAMILY SSF53774 1 325 2.75E-61 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 TL08_19450 e479a93151844f84687aafd2fe097c40 326 PIRSF PIRSF001220 1 325 6.3E-55 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TL08_19450 e479a93151844f84687aafd2fe097c40 326 SMART SM00870 3 320 2.7E-58 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TL08_19450 e479a93151844f84687aafd2fe097c40 326 Gene3D G3DSA:3.40.50.40 210 324 7.6E-27 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 TL08_20780 e30d54d06de763c7eda02e4a9adf0ecd 442 SUPERFAMILY SSF51735 5 168 3.21E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_20780 e30d54d06de763c7eda02e4a9adf0ecd 442 Gene3D G3DSA:3.40.50.720 3 139 1.8E-27 T 12-10-2018 TL08_20780 e30d54d06de763c7eda02e4a9adf0ecd 442 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 226 2.8E-17 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TL08_20780 e30d54d06de763c7eda02e4a9adf0ecd 442 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 136 2.9E-19 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_20780 e30d54d06de763c7eda02e4a9adf0ecd 442 SUPERFAMILY SSF55347 142 334 7.85E-30 T 12-10-2018 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 PRINTS PR00981 Seryl-tRNA synthetase signature 265 277 2.1E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 PRINTS PR00981 Seryl-tRNA synthetase signature 277 290 2.1E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 PRINTS PR00981 Seryl-tRNA synthetase signature 317 330 2.1E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 PRINTS PR00981 Seryl-tRNA synthetase signature 352 368 2.1E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 PRINTS PR00981 Seryl-tRNA synthetase signature 334 350 2.1E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 9.5E-19 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 12 417 2.3E-137 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 37.245 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 Gene3D G3DSA:1.10.287.40 1 104 1.4E-13 T 12-10-2018 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 SUPERFAMILY SSF46589 1 112 1.1E-19 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 Gene3D G3DSA:3.30.930.10 105 424 9.3E-112 T 12-10-2018 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 SUPERFAMILY SSF55681 122 424 9.67E-93 T 12-10-2018 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 224 400 2.2E-34 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_10770 045d93abcec819f4dda64efedf97ba80 424 PIRSF PIRSF001529 1 424 5.7E-145 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TL08_25465 ef74344a899aa7f44f05e155c6c4945d 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 4.5E-17 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal TL08_25465 ef74344a899aa7f44f05e155c6c4945d 174 Gene3D G3DSA:1.10.10.10 1 88 2.8E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25465 ef74344a899aa7f44f05e155c6c4945d 174 SUPERFAMILY SSF46785 4 166 1.33E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_14810 14875c7fe5daf494a33b5d1f898606c5 573 Gene3D G3DSA:3.90.76.10 63 224 1.4E-29 T 12-10-2018 TL08_14810 14875c7fe5daf494a33b5d1f898606c5 573 PIRSF PIRSF002741 4 566 7.0E-65 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_14810 14875c7fe5daf494a33b5d1f898606c5 573 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 99 481 7.7E-62 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_14810 14875c7fe5daf494a33b5d1f898606c5 573 Gene3D G3DSA:3.10.105.10 322 538 4.4E-56 T 12-10-2018 TL08_14810 14875c7fe5daf494a33b5d1f898606c5 573 SUPERFAMILY SSF53850 53 564 9.23E-88 T 12-10-2018 TL08_25170 4c553c2f86b021debdf9a703e3da3a89 625 Gene3D G3DSA:1.20.1560.10 45 367 7.1E-73 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_25170 4c553c2f86b021debdf9a703e3da3a89 625 ProSitePatterns PS00211 ABC transporters family signature. 522 536 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_25170 4c553c2f86b021debdf9a703e3da3a89 625 SUPERFAMILY SSF90123 50 371 1.24E-67 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_25170 4c553c2f86b021debdf9a703e3da3a89 625 SUPERFAMILY SSF52540 374 619 3.91E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25170 4c553c2f86b021debdf9a703e3da3a89 625 SMART SM00382 410 596 7.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_25170 4c553c2f86b021debdf9a703e3da3a89 625 Pfam PF00005 ABC transporter 401 550 6.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_25170 4c553c2f86b021debdf9a703e3da3a89 625 Pfam PF00664 ABC transporter transmembrane region 65 332 1.1E-38 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_25170 4c553c2f86b021debdf9a703e3da3a89 625 Gene3D G3DSA:3.40.50.300 375 623 2.3E-85 T 12-10-2018 TL08_20940 dd09a447791887c21ba17c00276ee3ec 336 Pfam PF13280 WYL domain 141 306 4.2E-27 T 12-10-2018 IPR026881 WYL domain TL08_20940 dd09a447791887c21ba17c00276ee3ec 336 PIRSF PIRSF016838 2 315 2.7E-20 T 12-10-2018 IPR028349 Protein PafC TL08_20940 dd09a447791887c21ba17c00276ee3ec 336 SMART SM00420 7 59 0.0048 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_20940 dd09a447791887c21ba17c00276ee3ec 336 SUPERFAMILY SSF46785 4 61 1.88E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_20940 dd09a447791887c21ba17c00276ee3ec 336 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TL08_20940 dd09a447791887c21ba17c00276ee3ec 336 Pfam PF08279 HTH domain 7 62 2.5E-12 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TL08_20940 dd09a447791887c21ba17c00276ee3ec 336 Gene3D G3DSA:1.10.10.10 3 64 1.4E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 Gene3D G3DSA:1.10.10.10 4 76 1.9E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 Gene3D G3DSA:3.40.1410.10 98 244 2.9E-29 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 9.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 9.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 SUPERFAMILY SSF64288 62 240 1.57E-32 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 SUPERFAMILY SSF46785 7 81 1.04E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 Pfam PF07702 UTRA domain 105 238 1.6E-23 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 SMART SM00866 97 240 2.2E-11 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 1.1E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_03350 dfdac5e994f3e0ebfedc0f14757e1aa5 247 SMART SM00345 15 74 4.2E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_12375 87e776814430d579d16117c1a11d2d1c 405 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 84 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_12375 87e776814430d579d16117c1a11d2d1c 405 SUPERFAMILY SSF103473 23 391 4.58E-29 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_12375 87e776814430d579d16117c1a11d2d1c 405 Pfam PF07690 Major Facilitator Superfamily 22 200 1.9E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_12375 87e776814430d579d16117c1a11d2d1c 405 Gene3D G3DSA:1.20.1250.20 17 386 1.8E-28 T 12-10-2018 TL08_09910 aa35240446fb019c7e5b3cc29d7edd11 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 83 6.8E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09910 aa35240446fb019c7e5b3cc29d7edd11 234 Gene3D G3DSA:1.10.10.10 10 86 3.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_09910 aa35240446fb019c7e5b3cc29d7edd11 234 SMART SM00345 28 86 1.3E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09910 aa35240446fb019c7e5b3cc29d7edd11 234 SUPERFAMILY SSF46785 23 89 1.57E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_09910 aa35240446fb019c7e5b3cc29d7edd11 234 Gene3D G3DSA:1.20.120.530 92 227 2.2E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_09910 aa35240446fb019c7e5b3cc29d7edd11 234 Pfam PF07729 FCD domain 97 217 4.9E-20 T 12-10-2018 IPR011711 GntR, C-terminal TL08_09910 aa35240446fb019c7e5b3cc29d7edd11 234 SUPERFAMILY SSF48008 93 220 1.67E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_09910 aa35240446fb019c7e5b3cc29d7edd11 234 SMART SM00895 97 218 4.8E-20 T 12-10-2018 IPR011711 GntR, C-terminal TL08_09820 4dbdb7701d6aab63f6e4801663a72d0b 1120 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 562 573 - T 12-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 TL08_09820 4dbdb7701d6aab63f6e4801663a72d0b 1120 Pfam PF00149 Calcineurin-like phosphoesterase 771 950 1.1E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_09820 4dbdb7701d6aab63f6e4801663a72d0b 1120 Pfam PF09992 Phosphodiester glycosidase 236 399 5.3E-30 T 12-10-2018 IPR018711 Phosphodiester glycosidase TL08_09820 4dbdb7701d6aab63f6e4801663a72d0b 1120 Gene3D G3DSA:3.60.21.10 756 1030 4.2E-24 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_09820 4dbdb7701d6aab63f6e4801663a72d0b 1120 SUPERFAMILY SSF56300 771 989 1.9E-25 T 12-10-2018 TL08_18745 0b50bc402060e74e545f3c3db8ee9127 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 136 1.1E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_18745 0b50bc402060e74e545f3c3db8ee9127 141 Gene3D G3DSA:3.10.180.10 2 141 3.6E-42 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_18745 0b50bc402060e74e545f3c3db8ee9127 141 SUPERFAMILY SSF54593 1 139 2.42E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_18745 0b50bc402060e74e545f3c3db8ee9127 141 ProSitePatterns PS00934 Glyoxalase I signature 1. 7 28 - T 12-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 TL08_21995 d1ba7efce1f49b087d1d0bbc2fc9977f 172 Pfam PF04978 Protein of unknown function (DUF664) 18 168 3.7E-45 T 12-10-2018 IPR007061 Protein of unknown function DUF664 TL08_21995 d1ba7efce1f49b087d1d0bbc2fc9977f 172 Gene3D G3DSA:1.20.120.450 6 171 1.9E-37 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_21995 d1ba7efce1f49b087d1d0bbc2fc9977f 172 SUPERFAMILY SSF109854 3 167 2.9E-44 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_05565 9c8090de02e8b956998d18cf86669ddb 416 SUPERFAMILY SSF51679 12 414 2.06E-65 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_05565 9c8090de02e8b956998d18cf86669ddb 416 PIRSF PIRSF000337 3 415 5.6E-76 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 TL08_05565 9c8090de02e8b956998d18cf86669ddb 416 Pfam PF00296 Luciferase-like monooxygenase 23 393 1.6E-44 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_08705 b910a1f569fb56ed343cde0694797c82 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 3.0E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_08705 b910a1f569fb56ed343cde0694797c82 227 SUPERFAMILY SSF52172 3 171 8.4E-38 T 12-10-2018 IPR011006 CheY-like superfamily TL08_08705 b910a1f569fb56ed343cde0694797c82 227 SMART SM00862 146 222 1.1E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_08705 b910a1f569fb56ed343cde0694797c82 227 Pfam PF00072 Response regulator receiver domain 5 112 6.2E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_08705 b910a1f569fb56ed343cde0694797c82 227 Gene3D G3DSA:3.40.50.2300 2 124 3.2E-33 T 12-10-2018 TL08_08705 b910a1f569fb56ed343cde0694797c82 227 SMART SM00448 2 112 1.3E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_08705 b910a1f569fb56ed343cde0694797c82 227 Gene3D G3DSA:1.10.10.10 125 226 1.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26240 427d0c13d7a9379ddf8e26f2f3bc8e41 466 Pfam PF00144 Beta-lactamase 29 328 7.3E-48 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_26240 427d0c13d7a9379ddf8e26f2f3bc8e41 466 SUPERFAMILY SSF56601 31 329 7.72E-62 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_26240 427d0c13d7a9379ddf8e26f2f3bc8e41 466 Gene3D G3DSA:3.40.710.10 18 329 1.0E-63 T 12-10-2018 TL08_05160 9d22bef93d24f8671526e6ea95447d76 263 Pfam PF13462 Thioredoxin 84 259 1.0E-18 T 12-10-2018 IPR012336 Thioredoxin-like fold TL08_05160 9d22bef93d24f8671526e6ea95447d76 263 SUPERFAMILY SSF52833 80 255 8.7E-25 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_05160 9d22bef93d24f8671526e6ea95447d76 263 Gene3D G3DSA:3.40.30.10 55 260 3.8E-42 T 12-10-2018 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 438 1.1E-11 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 Gene3D G3DSA:3.40.120.10 172 361 9.7E-70 T 12-10-2018 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 1.1E-13 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 1.1E-13 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.1E-13 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 441 6.2E-181 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 443 44.434 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 SUPERFAMILY SSF53738 256 362 1.84E-28 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 SUPERFAMILY SSF53738 150 254 2.32E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 135 5.5E-40 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 166 252 3.0E-20 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 365 6.4E-32 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 Gene3D G3DSA:3.40.120.10 3 154 1.9E-46 T 12-10-2018 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 Gene3D G3DSA:3.40.120.10 255 338 9.7E-70 T 12-10-2018 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 SUPERFAMILY SSF53738 4 179 1.37E-45 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 Gene3D G3DSA:3.30.310.50 369 444 8.6E-25 T 12-10-2018 TL08_24915 bc667120aa2f372de54a24d7f6e0dae4 444 SUPERFAMILY SSF55957 356 442 5.62E-21 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TL08_02125 b6e56fad1df24be1c1141651114350d0 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.9E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_02125 b6e56fad1df24be1c1141651114350d0 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.9E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_02125 b6e56fad1df24be1c1141651114350d0 252 Gene3D G3DSA:3.40.1410.10 83 248 1.2E-61 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_02125 b6e56fad1df24be1c1141651114350d0 252 SUPERFAMILY SSF46785 15 90 8.06E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_02125 b6e56fad1df24be1c1141651114350d0 252 SMART SM00345 23 80 1.7E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_02125 b6e56fad1df24be1c1141651114350d0 252 SUPERFAMILY SSF64288 68 246 3.3E-55 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_02125 b6e56fad1df24be1c1141651114350d0 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 79 1.1E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_02125 b6e56fad1df24be1c1141651114350d0 252 Gene3D G3DSA:1.10.10.10 18 82 2.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_02125 b6e56fad1df24be1c1141651114350d0 252 Pfam PF07702 UTRA domain 100 240 1.2E-45 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_02125 b6e56fad1df24be1c1141651114350d0 252 SMART SM00866 100 240 2.7E-46 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_10540 86d3b2e5119d63f4cf537edbd891a553 238 SMART SM00849 12 214 8.6E-32 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_10540 86d3b2e5119d63f4cf537edbd891a553 238 Pfam PF00753 Metallo-beta-lactamase superfamily 9 198 8.2E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_10540 86d3b2e5119d63f4cf537edbd891a553 238 SUPERFAMILY SSF56281 6 231 2.88E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_10540 86d3b2e5119d63f4cf537edbd891a553 238 Gene3D G3DSA:3.60.15.10 2 235 2.0E-59 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 44 266 6.0E-91 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 Gene3D G3DSA:1.10.10.10 195 267 2.7E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 PRINTS PR00046 Major sigma-70 factor signature 74 87 5.8E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 PRINTS PR00046 Major sigma-70 factor signature 251 262 5.8E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 PRINTS PR00046 Major sigma-70 factor signature 236 251 5.8E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 PRINTS PR00046 Major sigma-70 factor signature 219 231 5.8E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 Gene3D G3DSA:1.20.120.1810 10 118 1.9E-20 T 12-10-2018 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 Gene3D G3DSA:1.10.10.10 119 172 8.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 Pfam PF04539 Sigma-70 region 3 134 197 6.0E-11 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 SUPERFAMILY SSF88659 123 197 3.36E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 46 265 1.2E-37 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 SUPERFAMILY SSF88946 23 120 6.93E-31 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 Pfam PF04542 Sigma-70 region 2 50 120 3.7E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 Pfam PF04545 Sigma-70, region 4 215 264 1.8E-16 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TL08_17835 da3f10dcc9806fd99d5e331efc913e94 267 SUPERFAMILY SSF88659 188 265 3.55E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_26635 2715b3ea6f3ca2fa6f832c78a804623b 344 SMART SM00849 75 299 3.0E-7 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_26635 2715b3ea6f3ca2fa6f832c78a804623b 344 Pfam PF13483 Beta-lactamase superfamily domain 70 209 2.0E-9 T 12-10-2018 TL08_26635 2715b3ea6f3ca2fa6f832c78a804623b 344 SUPERFAMILY SSF56281 66 305 7.6E-23 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_26635 2715b3ea6f3ca2fa6f832c78a804623b 344 Gene3D G3DSA:3.60.15.10 58 324 1.2E-25 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 Pfam PF01571 Aminomethyltransferase folate-binding domain 2 241 4.0E-78 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 Gene3D G3DSA:4.10.1250.10 221 260 3.3E-11 T 12-10-2018 TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 SUPERFAMILY SSF103025 1 262 1.16E-81 T 12-10-2018 TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 345 6.1E-87 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 Gene3D G3DSA:3.30.1360.120 2 217 5.7E-70 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 Gene3D G3DSA:2.40.30.110 262 346 1.2E-22 T 12-10-2018 TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 SUPERFAMILY SSF101790 255 346 2.78E-22 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 PIRSF PIRSF006487 1 349 2.2E-79 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 Gene3D G3DSA:3.30.70.1400 37 122 5.7E-70 T 12-10-2018 TL08_21845 d714f29ab3d6c594988fdf51e0d329ef 349 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 248 340 3.8E-20 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TL08_19060 98926dcac76489fcc0d321a1184b4e5e 145 SUPERFAMILY SSF82784 1 135 1.05E-29 T 12-10-2018 IPR036102 OsmC/Ohr superfamily TL08_19060 98926dcac76489fcc0d321a1184b4e5e 145 Pfam PF02566 OsmC-like protein 44 140 4.4E-16 T 12-10-2018 IPR003718 OsmC/Ohr family TL08_19060 98926dcac76489fcc0d321a1184b4e5e 145 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 3 142 1.3E-48 T 12-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 TL08_19060 98926dcac76489fcc0d321a1184b4e5e 145 Gene3D G3DSA:3.30.300.20 2 144 2.3E-36 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_13615 7bf18ec8dd3bada5fc450be1b90310cc 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 125 1.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13615 7bf18ec8dd3bada5fc450be1b90310cc 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 89 1.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13615 7bf18ec8dd3bada5fc450be1b90310cc 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 105 1.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13615 7bf18ec8dd3bada5fc450be1b90310cc 166 Pfam PF12802 MarR family 55 113 1.1E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13615 7bf18ec8dd3bada5fc450be1b90310cc 166 Gene3D G3DSA:1.10.10.10 25 165 4.6E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_13615 7bf18ec8dd3bada5fc450be1b90310cc 166 SUPERFAMILY SSF46785 22 162 1.57E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_13615 7bf18ec8dd3bada5fc450be1b90310cc 166 SMART SM00347 50 150 1.4E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_08660 c43acd5d14bdd71d16da7b79f710d86a 319 Gene3D G3DSA:3.40.50.720 4 246 5.7E-116 T 12-10-2018 TL08_08660 c43acd5d14bdd71d16da7b79f710d86a 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 246 9.2E-59 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_08660 c43acd5d14bdd71d16da7b79f710d86a 319 Gene3D G3DSA:3.90.25.10 170 299 5.7E-116 T 12-10-2018 TL08_08660 c43acd5d14bdd71d16da7b79f710d86a 319 SUPERFAMILY SSF51735 2 314 8.66E-89 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_08660 c43acd5d14bdd71d16da7b79f710d86a 319 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 315 2.5E-117 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 TL08_15690 a2fe327d5efe1f3a2405f5cb83ddba75 413 SUPERFAMILY SSF103473 16 409 1.26E-42 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_15690 a2fe327d5efe1f3a2405f5cb83ddba75 413 Pfam PF00083 Sugar (and other) transporter 60 168 1.7E-5 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TL08_15690 a2fe327d5efe1f3a2405f5cb83ddba75 413 Pfam PF07690 Major Facilitator Superfamily 246 404 1.6E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_15690 a2fe327d5efe1f3a2405f5cb83ddba75 413 Gene3D G3DSA:1.20.1250.20 233 412 6.7E-19 T 12-10-2018 TL08_15690 a2fe327d5efe1f3a2405f5cb83ddba75 413 Gene3D G3DSA:1.20.1250.20 46 203 4.0E-15 T 12-10-2018 TL08_23440 b37a115093dbab541b0b818379e1d900 522 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 127 296 1.2E-36 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TL08_23440 b37a115093dbab541b0b818379e1d900 522 Gene3D G3DSA:3.30.70.2390 399 481 4.5E-6 T 12-10-2018 TL08_23440 b37a115093dbab541b0b818379e1d900 522 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 127 296 1.8E-41 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TL08_23440 b37a115093dbab541b0b818379e1d900 522 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 401 484 6.3E-16 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain TL08_23440 b37a115093dbab541b0b818379e1d900 522 Gene3D G3DSA:1.10.260.150 77 396 6.3E-70 T 12-10-2018 TL08_13825 1e2147fba28e4285ea5592d4894e811e 271 Gene3D G3DSA:1.10.260.40 3 84 6.8E-9 T 12-10-2018 TL08_13825 1e2147fba28e4285ea5592d4894e811e 271 Gene3D G3DSA:3.30.450.180 107 270 6.1E-8 T 12-10-2018 TL08_13825 1e2147fba28e4285ea5592d4894e811e 271 SMART SM00530 9 81 4.3E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_13825 1e2147fba28e4285ea5592d4894e811e 271 Pfam PF13560 Helix-turn-helix domain 5 84 1.0E-15 T 12-10-2018 TL08_13825 1e2147fba28e4285ea5592d4894e811e 271 SUPERFAMILY SSF47413 29 81 4.79E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_23845 e21a0f57b00a9a07c35df7220d51468b 465 SUPERFAMILY SSF53649 2 372 2.99E-74 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TL08_23845 e21a0f57b00a9a07c35df7220d51468b 465 Gene3D G3DSA:3.40.720.10 1 266 2.0E-37 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TL08_23845 e21a0f57b00a9a07c35df7220d51468b 465 Gene3D G3DSA:3.30.1360.110 281 347 2.6E-6 T 12-10-2018 IPR023116 Phosphonoacetate hydrolase, insert domain superfamily KEGG: 00440+3.11.1.2 TL08_23845 e21a0f57b00a9a07c35df7220d51468b 465 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 369 2.1E-59 T 12-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 TL08_07610 0268ed80ef9733bd271636c1efc4088e 663 Gene3D G3DSA:3.20.20.80 3 391 6.6E-130 T 12-10-2018 TL08_07610 0268ed80ef9733bd271636c1efc4088e 663 Pfam PF02449 Beta-galactosidase 17 383 1.2E-139 T 12-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_07610 0268ed80ef9733bd271636c1efc4088e 663 Gene3D G3DSA:2.60.40.1180 607 662 2.4E-6 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_07610 0268ed80ef9733bd271636c1efc4088e 663 PIRSF PIRSF001084 5 663 1.6E-241 T 12-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_07610 0268ed80ef9733bd271636c1efc4088e 663 Gene3D G3DSA:3.40.50.880 393 601 8.8E-66 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_07610 0268ed80ef9733bd271636c1efc4088e 663 Pfam PF08532 Beta-galactosidase trimerisation domain 396 599 3.8E-62 T 12-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TL08_07610 0268ed80ef9733bd271636c1efc4088e 663 SUPERFAMILY SSF52317 395 599 4.96E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_07610 0268ed80ef9733bd271636c1efc4088e 663 SUPERFAMILY SSF51445 10 365 9.15E-105 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_25015 01e53f59258cf085d1fd81a68483dd50 267 Pfam PF04672 S-adenosyl methyltransferase 14 231 2.9E-69 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_25015 01e53f59258cf085d1fd81a68483dd50 267 SUPERFAMILY SSF53335 8 231 4.01E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_25015 01e53f59258cf085d1fd81a68483dd50 267 Gene3D G3DSA:3.40.50.150 2 266 9.1E-83 T 12-10-2018 TL08_25015 01e53f59258cf085d1fd81a68483dd50 267 PIRSF PIRSF017393 1 264 4.5E-74 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_19190 81b0ff0b958007575ff08e1f0bd903bd 248 SMART SM00882 6 235 2.7E-90 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 TL08_19190 81b0ff0b958007575ff08e1f0bd903bd 248 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 237 4.2E-73 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 TL08_19190 81b0ff0b958007575ff08e1f0bd903bd 248 Gene3D G3DSA:3.40.1080.10 1 234 1.6E-101 T 12-10-2018 TL08_19190 81b0ff0b958007575ff08e1f0bd903bd 248 Pfam PF01144 Coenzyme A transferase 8 234 8.1E-77 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 TL08_19190 81b0ff0b958007575ff08e1f0bd903bd 248 SUPERFAMILY SSF100950 2 246 8.37E-91 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_19190 81b0ff0b958007575ff08e1f0bd903bd 248 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 12-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 TL08_06260 478dca6a2fbe26801de632397fe3adbb 199 Gene3D G3DSA:2.60.40.1220 28 128 4.3E-23 T 12-10-2018 TL08_06260 478dca6a2fbe26801de632397fe3adbb 199 Pfam PF04234 CopC domain 28 121 1.1E-20 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 TL08_06260 478dca6a2fbe26801de632397fe3adbb 199 SUPERFAMILY SSF81296 27 121 2.1E-20 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_17575 663c4f5b4abff8c99c05f113fabd3f20 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 5.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17575 663c4f5b4abff8c99c05f113fabd3f20 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17575 663c4f5b4abff8c99c05f113fabd3f20 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17575 663c4f5b4abff8c99c05f113fabd3f20 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17575 663c4f5b4abff8c99c05f113fabd3f20 210 Gene3D G3DSA:1.10.10.10 97 210 3.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17575 663c4f5b4abff8c99c05f113fabd3f20 210 SMART SM00421 147 204 2.2E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17575 663c4f5b4abff8c99c05f113fabd3f20 210 SUPERFAMILY SSF46894 141 210 2.18E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 369 432 3.4E-24 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 Pfam PF01926 50S ribosome-binding GTPase 161 288 7.5E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 Pfam PF01018 GTP1/OBG 5 157 7.3E-53 T 12-10-2018 IPR006169 GTP1/OBG domain TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 5.9E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 5.9E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 5.9E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 5.9E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 Gene3D G3DSA:2.70.210.12 1 158 3.8E-52 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 SUPERFAMILY SSF82051 4 157 4.19E-48 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 SUPERFAMILY SSF52540 161 339 8.99E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 Hamap MF_01454 GTPase Obg [obg]. 3 335 44.834 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 SUPERFAMILY SSF102741 368 433 4.71E-19 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 Pfam PF09269 Domain of unknown function (DUF1967) 368 431 3.6E-23 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 Gene3D G3DSA:3.40.50.300 160 348 1.6E-48 T 12-10-2018 TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 Gene3D G3DSA:2.40.240.60 359 434 5.5E-19 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily TL08_08190 9949202b5df6fca2555bf7ec49ba5abf 480 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 332 3.9E-126 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 SUPERFAMILY SSF47917 383 511 2.17E-44 T 12-10-2018 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 Gene3D G3DSA:3.40.50.300 97 382 2.1E-113 T 12-10-2018 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 SUPERFAMILY SSF52540 99 381 6.91E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 8.7E-14 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 Gene3D G3DSA:1.20.150.20 383 513 1.1E-47 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 1.2E-239 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 48.054 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 4.9E-66 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 4.4E-45 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 Gene3D G3DSA:2.40.30.20 4 96 2.7E-29 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_07325 9c69cd9fdf4567118da0425cee6a8edc 549 SUPERFAMILY SSF50615 14 97 1.65E-24 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_04360 f70a558cbf2e95d82ad3c18ff2ccefa2 371 SUPERFAMILY SSF56601 44 360 1.33E-64 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_04360 f70a558cbf2e95d82ad3c18ff2ccefa2 371 Pfam PF00144 Beta-lactamase 49 368 3.2E-50 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_04360 f70a558cbf2e95d82ad3c18ff2ccefa2 371 Gene3D G3DSA:3.40.710.10 27 370 7.2E-77 T 12-10-2018 TL08_17150 64c6b19044b8d5205877d10c0ed3ffda 440 SUPERFAMILY SSF50939 78 427 1.43E-62 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TL08_17150 64c6b19044b8d5205877d10c0ed3ffda 440 Gene3D G3DSA:2.120.10.10 53 432 3.6E-107 T 12-10-2018 TL08_17150 64c6b19044b8d5205877d10c0ed3ffda 440 Pfam PF13088 BNR repeat-like domain 97 394 3.2E-20 T 12-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TL08_24430 e11251cee001bae6de919985a7096c25 141 SUPERFAMILY SSF81343 15 137 3.27E-31 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24430 e11251cee001bae6de919985a7096c25 141 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 14 122 6.7E-15 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24430 e11251cee001bae6de919985a7096c25 141 Gene3D G3DSA:1.20.1300.10 21 135 6.4E-24 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 Gene3D G3DSA:1.20.58.410 2 114 2.7E-25 T 12-10-2018 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 363 36.298 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 SMART SM00937 83 193 1.0E-41 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 243 259 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 362 2.9E-150 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 Pfam PF00472 RF-1 domain 228 335 6.0E-38 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 Pfam PF03462 PCRF domain 29 218 1.2E-51 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 Gene3D G3DSA:3.30.160.20 224 318 5.2E-88 T 12-10-2018 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 Gene3D G3DSA:3.30.70.1660 128 356 5.2E-88 T 12-10-2018 TL08_04955 38962e77411e9f969197d50a88c1f7ef 366 SUPERFAMILY SSF75620 28 364 6.67E-119 T 12-10-2018 TL08_21410 7d8332941f93ac5e598ea4a1d6ac3b41 418 SUPERFAMILY SSF102114 31 417 2.35E-102 T 12-10-2018 TL08_21410 7d8332941f93ac5e598ea4a1d6ac3b41 418 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 42 375 2.9E-69 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 TL08_21410 7d8332941f93ac5e598ea4a1d6ac3b41 418 Gene3D G3DSA:3.80.30.20 21 343 1.7E-91 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TL08_21410 7d8332941f93ac5e598ea4a1d6ac3b41 418 Pfam PF04055 Radical SAM superfamily 44 219 5.8E-19 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_21410 7d8332941f93ac5e598ea4a1d6ac3b41 418 SMART SM00729 39 264 2.8E-54 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 SUPERFAMILY SSF46894 150 227 3.03E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 Pfam PF00072 Response regulator receiver domain 16 128 6.7E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 Gene3D G3DSA:3.40.50.12740 14 227 5.3E-61 T 12-10-2018 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 SMART SM00421 164 221 4.3E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 221 4.7E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 SMART SM00448 14 128 6.3E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 SUPERFAMILY SSF52172 13 146 3.13E-29 T 12-10-2018 IPR011006 CheY-like superfamily TL08_24715 ed9e4cb011eada39fe622baea837d840 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 8.7E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 8.7E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24715 ed9e4cb011eada39fe622baea837d840 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 8.7E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_23445 52035e40ff894d5bb29327d2c37044ea 511 Gene3D G3DSA:1.10.260.150 161 461 1.8E-61 T 12-10-2018 TL08_23445 52035e40ff894d5bb29327d2c37044ea 511 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 202 371 5.7E-30 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TL08_23445 52035e40ff894d5bb29327d2c37044ea 511 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 202 371 2.3E-34 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TL08_02590 ac6c309a423b83129828a713325e6e2c 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 98 114 3.5E-14 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_02590 ac6c309a423b83129828a713325e6e2c 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 50 70 3.5E-14 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_02590 ac6c309a423b83129828a713325e6e2c 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 147 170 3.5E-14 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_02590 ac6c309a423b83129828a713325e6e2c 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 192 213 3.5E-14 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_02590 ac6c309a423b83129828a713325e6e2c 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 223 247 3.5E-14 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_02590 ac6c309a423b83129828a713325e6e2c 277 SUPERFAMILY SSF56655 15 272 5.89E-42 T 12-10-2018 TL08_02590 ac6c309a423b83129828a713325e6e2c 277 Gene3D G3DSA:3.30.540.10 11 155 4.0E-26 T 12-10-2018 TL08_02590 ac6c309a423b83129828a713325e6e2c 277 Gene3D G3DSA:3.40.190.80 160 277 1.7E-12 T 12-10-2018 TL08_02590 ac6c309a423b83129828a713325e6e2c 277 Pfam PF00459 Inositol monophosphatase family 21 261 1.0E-31 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 Gene3D G3DSA:3.20.20.70 18 318 5.4E-88 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 Pfam PF00701 Dihydrodipicolinate synthetase family 19 315 1.0E-49 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 SUPERFAMILY SSF51569 17 317 2.41E-73 T 12-10-2018 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 PRINTS PR00146 Dihydrodipicolinate synthase signature 144 161 1.9E-10 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 PRINTS PR00146 Dihydrodipicolinate synthase signature 87 105 1.9E-10 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 PRINTS PR00146 Dihydrodipicolinate synthase signature 119 135 1.9E-10 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 PRINTS PR00146 Dihydrodipicolinate synthase signature 51 72 1.9E-10 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 SMART SM01130 17 317 3.6E-79 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 149 179 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TL08_09825 eaaeec303da1f4463f9cbe86fdc4c672 323 PIRSF PIRSF001365 17 320 1.1E-71 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_03830 5d7aa05ef6f6568a580cb45539061591 382 SUPERFAMILY SSF56059 194 355 9.6E-12 T 12-10-2018 TL08_03830 5d7aa05ef6f6568a580cb45539061591 382 Gene3D G3DSA:3.30.470.20 265 373 1.2E-11 T 12-10-2018 TL08_03830 5d7aa05ef6f6568a580cb45539061591 382 Pfam PF08443 RimK-like ATP-grasp domain 258 352 2.0E-4 T 12-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 TL08_02515 c2b468b756a884b874faff9c446474c1 290 Pfam PF01040 UbiA prenyltransferase family 20 249 2.0E-33 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TL08_02515 c2b468b756a884b874faff9c446474c1 290 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 287 20.643 T 12-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TL08_02515 c2b468b756a884b874faff9c446474c1 290 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 282 3.5E-83 T 12-10-2018 TL08_02515 c2b468b756a884b874faff9c446474c1 290 PIRSF PIRSF005355 1 290 2.4E-83 T 12-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 TL08_18255 54476f0f8810c63459ba2b32b2f6b3b7 673 Gene3D G3DSA:1.20.1260.20 44 206 3.2E-10 T 12-10-2018 IPR038332 PPE superfamily TL08_18255 54476f0f8810c63459ba2b32b2f6b3b7 673 SUPERFAMILY SSF140459 37 204 2.01E-9 T 12-10-2018 TL08_18255 54476f0f8810c63459ba2b32b2f6b3b7 673 Pfam PF00823 PPE family 59 190 8.6E-8 T 12-10-2018 IPR000030 PPE family TL08_17285 5e19e943333b14b2473d6482b39f1867 214 Gene3D G3DSA:1.20.120.530 74 204 1.1E-15 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_17285 5e19e943333b14b2473d6482b39f1867 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 1.4E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_17285 5e19e943333b14b2473d6482b39f1867 214 SUPERFAMILY SSF46785 6 72 1.94E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17285 5e19e943333b14b2473d6482b39f1867 214 Gene3D G3DSA:1.10.10.10 1 69 3.4E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17285 5e19e943333b14b2473d6482b39f1867 214 SUPERFAMILY SSF48008 78 203 5.23E-15 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_17285 5e19e943333b14b2473d6482b39f1867 214 SMART SM00345 10 68 7.6E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_17285 5e19e943333b14b2473d6482b39f1867 214 SMART SM00895 78 201 5.8E-6 T 12-10-2018 IPR011711 GntR, C-terminal TL08_17285 5e19e943333b14b2473d6482b39f1867 214 Pfam PF07729 FCD domain 82 197 2.5E-15 T 12-10-2018 IPR011711 GntR, C-terminal TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 Pfam PF13354 Beta-lactamase enzyme family 78 285 3.0E-36 T 12-10-2018 TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 PRINTS PR00118 Beta-lactamase class A signature 166 190 8.3E-68 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 PRINTS PR00118 Beta-lactamase class A signature 130 155 8.3E-68 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 PRINTS PR00118 Beta-lactamase class A signature 88 105 8.3E-68 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 PRINTS PR00118 Beta-lactamase class A signature 228 243 8.3E-68 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 PRINTS PR00118 Beta-lactamase class A signature 57 81 8.3E-68 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 PRINTS PR00118 Beta-lactamase class A signature 192 217 8.3E-68 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 PRINTS PR00118 Beta-lactamase class A signature 245 260 8.3E-68 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 SUPERFAMILY SSF56601 54 312 1.82E-69 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 ProSitePatterns PS00146 Beta-lactamase class-A active site. 90 105 - T 12-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 TL08_13815 29206eaeedfdd6be6b441db04fdcbd63 316 Gene3D G3DSA:3.40.710.10 49 315 7.4E-76 T 12-10-2018 TL08_25855 bb78811c649edbd9f8e27c3d547e8ad7 384 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 109 127 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 TL08_25855 bb78811c649edbd9f8e27c3d547e8ad7 384 Gene3D G3DSA:3.20.20.70 21 264 5.3E-80 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_25855 bb78811c649edbd9f8e27c3d547e8ad7 384 PIRSF PIRSF006621 14 348 3.3E-112 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TL08_25855 bb78811c649edbd9f8e27c3d547e8ad7 384 Pfam PF01207 Dihydrouridine synthase (Dus) 27 328 3.0E-103 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TL08_25855 bb78811c649edbd9f8e27c3d547e8ad7 384 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 17 338 2.5E-119 T 12-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 TL08_25855 bb78811c649edbd9f8e27c3d547e8ad7 384 SUPERFAMILY SSF51395 25 334 2.93E-85 T 12-10-2018 TL08_25855 bb78811c649edbd9f8e27c3d547e8ad7 384 Gene3D G3DSA:1.10.1200.80 272 336 3.1E-9 T 12-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 SUPERFAMILY SSF88946 12 110 8.77E-29 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 Pfam PF04545 Sigma-70, region 4 206 255 5.7E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 36 257 2.1E-88 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 257 2.0E-35 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 Pfam PF04539 Sigma-70 region 3 124 181 1.1E-11 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 Gene3D G3DSA:1.10.10.10 186 259 2.6E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11075 c447e9337f25073cf9a397e5721f023b 260 SUPERFAMILY SSF88659 183 259 8.22E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_11075 c447e9337f25073cf9a397e5721f023b 260 PRINTS PR00046 Major sigma-70 factor signature 227 242 1.7E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 PRINTS PR00046 Major sigma-70 factor signature 210 222 1.7E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 PRINTS PR00046 Major sigma-70 factor signature 65 78 1.7E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 PRINTS PR00046 Major sigma-70 factor signature 242 253 1.7E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 Gene3D G3DSA:1.20.120.1810 5 109 4.7E-20 T 12-10-2018 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 Pfam PF04542 Sigma-70 region 2 41 110 1.2E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_11075 c447e9337f25073cf9a397e5721f023b 260 SUPERFAMILY SSF88659 114 186 8.28E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_11075 c447e9337f25073cf9a397e5721f023b 260 Gene3D G3DSA:1.10.10.10 111 163 1.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_27105 cf94ac81bb9bf7d84cbc4df9e2d12091 440 SUPERFAMILY SSF53383 23 413 1.31E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_27105 cf94ac81bb9bf7d84cbc4df9e2d12091 440 Gene3D G3DSA:3.90.1150.10 36 410 1.2E-137 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_27105 cf94ac81bb9bf7d84cbc4df9e2d12091 440 Gene3D G3DSA:3.40.640.10 83 305 1.2E-137 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_27105 cf94ac81bb9bf7d84cbc4df9e2d12091 440 Pfam PF00155 Aminotransferase class I and II 61 407 1.1E-40 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_23380 3cb87eca82fae4114c0a37a8d185d50d 333 Pfam PF01933 Uncharacterised protein family UPF0052 3 295 1.9E-62 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 TL08_23380 3cb87eca82fae4114c0a37a8d185d50d 333 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 326 1.7E-117 T 12-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 TL08_23380 3cb87eca82fae4114c0a37a8d185d50d 333 Gene3D G3DSA:1.10.8.240 48 136 2.9E-91 T 12-10-2018 TL08_23380 3cb87eca82fae4114c0a37a8d185d50d 333 SUPERFAMILY SSF142338 3 329 6.28E-78 T 12-10-2018 TL08_23380 3cb87eca82fae4114c0a37a8d185d50d 333 Gene3D G3DSA:3.40.50.10680 7 305 2.9E-91 T 12-10-2018 TL08_23380 3cb87eca82fae4114c0a37a8d185d50d 333 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 333 130.95 T 12-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 TL08_27125 194a0c8741aa803b647c38e09b556486 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 35 207 1.0E-40 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TL08_27125 194a0c8741aa803b647c38e09b556486 238 SUPERFAMILY SSF53335 32 192 2.28E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_27125 194a0c8741aa803b647c38e09b556486 238 Gene3D G3DSA:3.40.50.150 8 238 2.4E-60 T 12-10-2018 TL08_27125 194a0c8741aa803b647c38e09b556486 238 Pfam PF02527 rRNA small subunit methyltransferase G 33 206 1.1E-50 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TL08_27125 194a0c8741aa803b647c38e09b556486 238 PIRSF PIRSF003078 12 223 5.4E-46 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TL08_27125 194a0c8741aa803b647c38e09b556486 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 22 203 24.563 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 TIGRFAM TIGR00115 tig: trigger factor 12 415 1.3E-112 T 12-10-2018 IPR005215 Trigger factor GO:0015031 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 416 2.1E-34 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 Gene3D G3DSA:3.30.70.1050 1 116 4.7E-31 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 Gene3D G3DSA:3.10.50.40 151 243 3.5E-60 T 12-10-2018 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 Pfam PF05697 Bacterial trigger factor protein (TF) 2 145 4.1E-37 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 SUPERFAMILY SSF102735 2 128 9.42E-32 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 SUPERFAMILY SSF109998 246 434 1.7E-41 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 PIRSF PIRSF003095 1 445 1.0E-109 T 12-10-2018 IPR005215 Trigger factor GO:0015031 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 Gene3D G3DSA:1.10.3120.10 117 423 3.5E-60 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 Hamap MF_00303 Trigger factor [tig]. 1 424 18.446 T 12-10-2018 IPR005215 Trigger factor GO:0015031 TL08_08045 57f5cdb530819bfa45bdc6db77c5b99c 477 SUPERFAMILY SSF54534 133 244 1.51E-18 T 12-10-2018 TL08_02800 03ac46eefd4541f19991d1904fdb4d97 295 Gene3D G3DSA:3.90.550.10 1 291 2.2E-74 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_02800 03ac46eefd4541f19991d1904fdb4d97 295 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 1.3E-138 T 12-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 TL08_02800 03ac46eefd4541f19991d1904fdb4d97 295 Pfam PF00483 Nucleotidyl transferase 2 237 5.1E-61 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TL08_02800 03ac46eefd4541f19991d1904fdb4d97 295 SUPERFAMILY SSF53448 2 285 1.73E-84 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_06720 e05708e34b102e522e5cc1a4d00d7ee3 282 SUPERFAMILY SSF53901 46 183 7.12E-8 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_06720 e05708e34b102e522e5cc1a4d00d7ee3 282 Gene3D G3DSA:3.40.47.10 6 191 1.8E-6 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_14000 886a61a31b5a06d774a60040a2b70fc7 170 Gene3D G3DSA:2.30.110.10 20 165 1.4E-31 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_14000 886a61a31b5a06d774a60040a2b70fc7 170 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 28 109 3.4E-15 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_14000 886a61a31b5a06d774a60040a2b70fc7 170 SUPERFAMILY SSF50475 27 160 5.81E-26 T 12-10-2018 TL08_09370 780aba2ace6881e725e2af1111284771 579 SMART SM00729 274 492 9.0E-37 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_09370 780aba2ace6881e725e2af1111284771 579 SUPERFAMILY SSF102114 254 496 6.02E-43 T 12-10-2018 TL08_09370 780aba2ace6881e725e2af1111284771 579 Pfam PF04055 Radical SAM superfamily 281 450 5.6E-19 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_09370 780aba2ace6881e725e2af1111284771 579 Gene3D G3DSA:2.40.50.140 507 572 2.6E-6 T 12-10-2018 TL08_09370 780aba2ace6881e725e2af1111284771 579 Gene3D G3DSA:3.80.30.20 271 506 1.7E-65 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TL08_09370 780aba2ace6881e725e2af1111284771 579 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 112 566 1.8E-117 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TL08_09370 780aba2ace6881e725e2af1111284771 579 Pfam PF00919 Uncharacterized protein family UPF0004 112 208 2.6E-27 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TL08_09370 780aba2ace6881e725e2af1111284771 579 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 111 569 57.053 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TL08_09370 780aba2ace6881e725e2af1111284771 579 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 112 559 2.9E-99 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TL08_09370 780aba2ace6881e725e2af1111284771 579 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 278 298 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TL08_09370 780aba2ace6881e725e2af1111284771 579 Gene3D G3DSA:3.40.50.12160 111 237 9.6E-31 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TL08_19940 1cf86714c3bb7d70262b3ec6038696fe 416 SUPERFAMILY SSF51905 1 364 3.4E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_19940 1cf86714c3bb7d70262b3ec6038696fe 416 Pfam PF01494 FAD binding domain 108 158 8.0E-6 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_19940 1cf86714c3bb7d70262b3ec6038696fe 416 Gene3D G3DSA:3.50.50.60 1 337 1.9E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_19940 1cf86714c3bb7d70262b3ec6038696fe 416 Gene3D G3DSA:3.30.9.50 34 266 1.9E-60 T 12-10-2018 TL08_19940 1cf86714c3bb7d70262b3ec6038696fe 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 3.7E-5 T 12-10-2018 TL08_19940 1cf86714c3bb7d70262b3ec6038696fe 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 3.7E-5 T 12-10-2018 TL08_19940 1cf86714c3bb7d70262b3ec6038696fe 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 3.7E-5 T 12-10-2018 TL08_15245 c84de82ed1c193be16694f0e62b2531f 572 Gene3D G3DSA:1.25.40.10 42 216 8.4E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15245 c84de82ed1c193be16694f0e62b2531f 572 SUPERFAMILY SSF48452 55 166 2.93E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15245 c84de82ed1c193be16694f0e62b2531f 572 Gene3D G3DSA:1.25.40.10 223 420 6.3E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15245 c84de82ed1c193be16694f0e62b2531f 572 Pfam PF13424 Tetratricopeptide repeat 93 166 9.1E-8 T 12-10-2018 TL08_15245 c84de82ed1c193be16694f0e62b2531f 572 Pfam PF13424 Tetratricopeptide repeat 225 285 8.4E-9 T 12-10-2018 TL08_15245 c84de82ed1c193be16694f0e62b2531f 572 SUPERFAMILY SSF48452 190 373 2.02E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15505 2b26a996197d9bc5e0526cfb5f636c73 267 SUPERFAMILY SSF56752 19 248 1.83E-32 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TL08_15505 2b26a996197d9bc5e0526cfb5f636c73 267 Gene3D G3DSA:3.20.10.10 120 262 2.5E-17 T 12-10-2018 TL08_15505 2b26a996197d9bc5e0526cfb5f636c73 267 Pfam PF01063 Amino-transferase class IV 28 238 7.4E-29 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TL08_11660 4aa5107cc136bf482c0df7395a6f857f 159 SUPERFAMILY SSF51735 1 148 3.49E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_11660 4aa5107cc136bf482c0df7395a6f857f 159 Gene3D G3DSA:3.40.50.720 1 158 1.7E-25 T 12-10-2018 TL08_11660 4aa5107cc136bf482c0df7395a6f857f 159 Pfam PF00106 short chain dehydrogenase 1 144 1.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_21060 931996dbca442dc7b9bad0f87f57a316 206 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 24 174 8.1E-27 T 12-10-2018 IPR000160 GGDEF domain TL08_21060 931996dbca442dc7b9bad0f87f57a316 206 Gene3D G3DSA:3.30.70.270 11 179 3.7E-40 T 12-10-2018 TL08_21060 931996dbca442dc7b9bad0f87f57a316 206 SUPERFAMILY SSF55073 30 173 2.83E-32 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_21060 931996dbca442dc7b9bad0f87f57a316 206 SMART SM00267 14 180 4.7E-32 T 12-10-2018 IPR000160 GGDEF domain TL08_21060 931996dbca442dc7b9bad0f87f57a316 206 Pfam PF00990 Diguanylate cyclase, GGDEF domain 27 173 7.3E-29 T 12-10-2018 IPR000160 GGDEF domain TL08_00730 fce4ced6a1edafb4d07d147083ae49db 399 Pfam PF00266 Aminotransferase class-V 21 235 3.4E-31 T 12-10-2018 IPR000192 Aminotransferase class V domain TL08_00730 fce4ced6a1edafb4d07d147083ae49db 399 Pfam PF00266 Aminotransferase class-V 295 391 1.8E-8 T 12-10-2018 IPR000192 Aminotransferase class V domain TL08_00730 fce4ced6a1edafb4d07d147083ae49db 399 Gene3D G3DSA:3.40.640.10 28 284 2.0E-121 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_00730 fce4ced6a1edafb4d07d147083ae49db 399 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 395 5.4E-125 T 12-10-2018 IPR011340 Cysteine desulfurase-related TL08_00730 fce4ced6a1edafb4d07d147083ae49db 399 SUPERFAMILY SSF53383 3 397 1.5E-66 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_00730 fce4ced6a1edafb4d07d147083ae49db 399 Gene3D G3DSA:3.90.1150.10 18 395 2.0E-121 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_16060 bd08a3afbc1aeaefe7a754426185e8e5 339 SUPERFAMILY SSF52540 5 233 4.91E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_16060 bd08a3afbc1aeaefe7a754426185e8e5 339 Gene3D G3DSA:3.40.50.300 2 242 3.5E-59 T 12-10-2018 TL08_16060 bd08a3afbc1aeaefe7a754426185e8e5 339 SMART SM00382 35 218 2.8E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_16060 bd08a3afbc1aeaefe7a754426185e8e5 339 Pfam PF00005 ABC transporter 26 170 4.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23945 8a1fcdab71f1d973188bfdd2f1178dd8 377 Pfam PF07730 Histidine kinase 196 258 9.8E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_23945 8a1fcdab71f1d973188bfdd2f1178dd8 377 SUPERFAMILY SSF55874 263 376 3.59E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_23945 8a1fcdab71f1d973188bfdd2f1178dd8 377 Gene3D G3DSA:3.30.565.10 256 377 1.7E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 SUPERFAMILY SSF50104 204 260 1.81E-17 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 SMART SM00738 75 183 1.5E-50 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 ProSitePatterns PS01014 Transcription termination factor nusG signature. 243 252 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 PRINTS PR00338 Transcription termination factor NUSG signature 218 233 4.3E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 PRINTS PR00338 Transcription termination factor NUSG signature 236 252 4.3E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 PRINTS PR00338 Transcription termination factor NUSG signature 130 142 4.3E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 Gene3D G3DSA:2.30.30.30 199 260 2.2E-25 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 SUPERFAMILY SSF82679 77 180 9.81E-36 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 75 260 24.349 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 78 260 5.9E-66 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 Gene3D G3DSA:3.30.70.940 72 190 8.7E-41 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TL08_02880 fdbdf8717b3ed0046bc69cd6cb8d8d8f 260 Pfam PF02357 Transcription termination factor nusG 77 179 8.0E-25 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TL08_25430 3c29d43447912a420162e6128eba8b3a 88 Pfam PF04226 Transglycosylase associated protein 36 85 4.9E-8 T 12-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Gene3D G3DSA:3.30.559.10 141 398 7.6E-54 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 10 43 3.0E-12 T 12-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 SMART SM00861 928 1121 4.6E-47 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 PIRSF PIRSF000157 2 1270 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Gene3D G3DSA:3.40.50.12470 887 1144 2.9E-157 T 12-10-2018 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 157 391 1.3E-55 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Gene3D G3DSA:3.40.50.11610 1064 1267 2.9E-157 T 12-10-2018 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Pfam PF02779 Transketolase, pyrimidine binding domain 927 1120 9.4E-54 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Gene3D G3DSA:1.10.287.1150 420 501 1.6E-28 T 12-10-2018 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Gene3D G3DSA:3.40.50.970 502 866 5.8E-144 T 12-10-2018 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1126 1269 1.9E-44 T 12-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 Pfam PF00676 Dehydrogenase E1 component 543 866 7.0E-58 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 SUPERFAMILY SSF52518 915 1127 4.42E-43 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 425 1268 2.3E-301 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 SUPERFAMILY SSF52777 152 391 3.07E-55 T 12-10-2018 TL08_23010 41e582afd038fe35b146c888dbeb784d 1270 SUPERFAMILY SSF52518 456 864 2.94E-84 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 SMART SM01403 22 116 2.8E-55 T 12-10-2018 IPR027486 Ribosomal protein S10 domain TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 Pfam PF00338 Ribosomal protein S10p/S20e 22 115 3.1E-34 T 12-10-2018 IPR027486 Ribosomal protein S10 domain TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 Gene3D G3DSA:3.30.70.600 7 116 2.5E-36 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 SUPERFAMILY SSF54999 20 115 2.22E-36 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 18 116 24.593 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 ProSitePatterns PS00361 Ribosomal protein S10 signature. 44 59 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 19 116 1.3E-45 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 PRINTS PR00971 Ribosomal protein S10 family signature 76 90 4.8E-21 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 PRINTS PR00971 Ribosomal protein S10 family signature 20 33 4.8E-21 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_02980 892ce85bfbd4e779d5722bc8b2e7727e 116 PRINTS PR00971 Ribosomal protein S10 family signature 55 70 4.8E-21 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_02505 d2625060ad0d4f7653741e91b0b74b93 448 Gene3D G3DSA:1.10.287.700 279 446 8.1E-8 T 12-10-2018 TL08_02505 d2625060ad0d4f7653741e91b0b74b93 448 SUPERFAMILY SSF58104 175 356 9.68E-5 T 12-10-2018 TL08_09110 c1b42ad96786e4c02c429bbdb2b470ec 385 SMART SM00090 124 377 1.0E-9 T 12-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TL08_09110 c1b42ad96786e4c02c429bbdb2b470ec 385 Pfam PF01163 RIO1 family 207 362 1.8E-29 T 12-10-2018 TL08_09110 c1b42ad96786e4c02c429bbdb2b470ec 385 SUPERFAMILY SSF56112 157 352 3.23E-12 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_09110 c1b42ad96786e4c02c429bbdb2b470ec 385 Gene3D G3DSA:1.10.510.10 281 368 1.2E-15 T 12-10-2018 TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 Gene3D G3DSA:2.130.10.120 75 436 3.6E-178 T 12-10-2018 TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 9 431 1.6E-43 T 12-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 SUPERFAMILY SSF53474 449 705 1.14E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 SUPERFAMILY SSF50993 8 430 9.15E-47 T 12-10-2018 TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 Gene3D G3DSA:3.40.50.1820 17 701 3.6E-178 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 Pfam PF00326 Prolyl oligopeptidase family 495 707 7.5E-45 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 561 581 3.3E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 531 550 3.3E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 503 527 3.3E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 635 657 3.3E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_16660 07f3ffc87dda02348c2582a6e05595fd 718 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 477 495 3.3E-36 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_00815 db8b36e225f70b4c6717d24b1da3bc82 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 2.1E-116 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_00815 db8b36e225f70b4c6717d24b1da3bc82 399 Pfam PF02803 Thiolase, C-terminal domain 277 398 8.0E-35 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TL08_00815 db8b36e225f70b4c6717d24b1da3bc82 399 Gene3D G3DSA:3.40.47.10 146 396 3.8E-127 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_00815 db8b36e225f70b4c6717d24b1da3bc82 399 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 TL08_00815 db8b36e225f70b4c6717d24b1da3bc82 399 Pfam PF00108 Thiolase, N-terminal domain 5 268 1.3E-55 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TL08_00815 db8b36e225f70b4c6717d24b1da3bc82 399 SUPERFAMILY SSF53901 278 398 1.24E-33 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_00815 db8b36e225f70b4c6717d24b1da3bc82 399 Gene3D G3DSA:3.40.47.10 6 282 3.8E-127 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_00815 db8b36e225f70b4c6717d24b1da3bc82 399 SUPERFAMILY SSF53901 1 272 3.51E-63 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_00815 db8b36e225f70b4c6717d24b1da3bc82 399 PIRSF PIRSF000429 1 399 1.3E-110 T 12-10-2018 IPR002155 Thiolase GO:0016747 TL08_04710 e936a38641846bc63879906beb39950a 172 Gene3D G3DSA:1.10.1740.10 1 75 1.4E-8 T 12-10-2018 TL08_04710 e936a38641846bc63879906beb39950a 172 Gene3D G3DSA:1.10.10.10 85 161 5.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04710 e936a38641846bc63879906beb39950a 172 SUPERFAMILY SSF88659 94 155 1.74E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_04710 e936a38641846bc63879906beb39950a 172 SUPERFAMILY SSF88946 3 76 2.9E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_04710 e936a38641846bc63879906beb39950a 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 154 5.8E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_04710 e936a38641846bc63879906beb39950a 172 Pfam PF08281 Sigma-70, region 4 100 153 9.7E-19 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_04710 e936a38641846bc63879906beb39950a 172 Pfam PF04542 Sigma-70 region 2 10 72 8.0E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_15225 b4e91978061a4a387220ca5917586a8b 344 SUPERFAMILY SSF51430 70 339 2.1E-75 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_15225 b4e91978061a4a387220ca5917586a8b 344 Pfam PF00248 Aldo/keto reductase family 79 339 2.1E-60 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_15225 b4e91978061a4a387220ca5917586a8b 344 PRINTS PR00069 Aldo-keto reductase signature 174 192 2.4E-8 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_15225 b4e91978061a4a387220ca5917586a8b 344 PRINTS PR00069 Aldo-keto reductase signature 276 300 2.4E-8 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_15225 b4e91978061a4a387220ca5917586a8b 344 PRINTS PR00069 Aldo-keto reductase signature 109 133 2.4E-8 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_15225 b4e91978061a4a387220ca5917586a8b 344 PRINTS PR00069 Aldo-keto reductase signature 205 222 2.4E-8 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_15225 b4e91978061a4a387220ca5917586a8b 344 Gene3D G3DSA:3.20.20.100 72 343 7.6E-81 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_02055 0219a6fce06370f028e82016033fbab4 288 Pfam PF08543 Phosphomethylpyrimidine kinase 28 277 1.5E-82 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 TL08_02055 0219a6fce06370f028e82016033fbab4 288 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 21 279 8.8E-84 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TL08_02055 0219a6fce06370f028e82016033fbab4 288 SUPERFAMILY SSF53613 17 282 7.48E-73 T 12-10-2018 IPR029056 Ribokinase-like TL08_02055 0219a6fce06370f028e82016033fbab4 288 Gene3D G3DSA:3.40.1190.20 12 287 1.1E-92 T 12-10-2018 IPR029056 Ribokinase-like TL08_12135 a7b31b669625bebd7a9e6dbcbe1d9ee0 384 SUPERFAMILY SSF53092 10 154 2.88E-17 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TL08_12135 a7b31b669625bebd7a9e6dbcbe1d9ee0 384 Gene3D G3DSA:3.40.350.10 9 153 1.9E-30 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TL08_12135 a7b31b669625bebd7a9e6dbcbe1d9ee0 384 Pfam PF01321 Creatinase/Prolidase N-terminal domain 17 155 1.5E-10 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TL08_12135 a7b31b669625bebd7a9e6dbcbe1d9ee0 384 Gene3D G3DSA:3.90.230.10 154 384 2.2E-79 T 12-10-2018 TL08_12135 a7b31b669625bebd7a9e6dbcbe1d9ee0 384 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 312 324 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TL08_12135 a7b31b669625bebd7a9e6dbcbe1d9ee0 384 SUPERFAMILY SSF55920 155 379 4.06E-71 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TL08_12135 a7b31b669625bebd7a9e6dbcbe1d9ee0 384 Pfam PF00557 Metallopeptidase family M24 166 366 7.1E-59 T 12-10-2018 IPR000994 Peptidase M24 TL08_22130 b642304627da181e632b30e229b38d34 335 Pfam PF11350 Protein of unknown function (DUF3152) 165 325 2.7E-44 T 12-10-2018 IPR022603 Domain of unknown function DUF3152 TL08_22130 b642304627da181e632b30e229b38d34 335 SUPERFAMILY SSF55486 190 326 2.53E-16 T 12-10-2018 TL08_09765 49073c3ce127c59f02168f13afca30c5 532 Pfam PF00425 chorismate binding enzyme 235 497 5.5E-95 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TL08_09765 49073c3ce127c59f02168f13afca30c5 532 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 37 505 4.2E-167 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_09765 49073c3ce127c59f02168f13afca30c5 532 Gene3D G3DSA:3.60.120.10 9 515 1.2E-200 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TL08_09765 49073c3ce127c59f02168f13afca30c5 532 SUPERFAMILY SSF56322 27 506 3.01E-152 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TL08_09765 49073c3ce127c59f02168f13afca30c5 532 PRINTS PR00095 Anthranilate synthase component I signature 359 372 3.5E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_09765 49073c3ce127c59f02168f13afca30c5 532 PRINTS PR00095 Anthranilate synthase component I signature 345 358 3.5E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_09765 49073c3ce127c59f02168f13afca30c5 532 PRINTS PR00095 Anthranilate synthase component I signature 439 453 3.5E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_09765 49073c3ce127c59f02168f13afca30c5 532 PRINTS PR00095 Anthranilate synthase component I signature 454 468 3.5E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_09765 49073c3ce127c59f02168f13afca30c5 532 Pfam PF04715 Anthranilate synthase component I, N terminal region 38 179 5.4E-31 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 SUPERFAMILY SSF53633 21 268 9.82E-56 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 SUPERFAMILY SSF88697 289 376 1.77E-16 T 12-10-2018 IPR015947 PUA-like superfamily TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 ProSitePatterns PS00902 Glutamate 5-kinase signature. 223 240 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 Hamap MF_00456 Glutamate 5-kinase [proB]. 21 273 33.854 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 TIGRFAM TIGR01027 proB: glutamate 5-kinase 21 375 7.9E-119 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 Pfam PF00696 Amino acid kinase family 22 249 2.1E-34 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 Gene3D G3DSA:3.40.1160.10 10 278 2.2E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 Gene3D G3DSA:2.30.130.10 279 377 3.1E-22 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 PIRSF PIRSF000729 16 378 5.4E-114 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 SMART SM00359 290 369 2.3E-16 T 12-10-2018 IPR002478 PUA domain GO:0003723 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 Pfam PF01472 PUA domain 290 359 3.8E-17 T 12-10-2018 IPR002478 PUA domain GO:0003723 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 PRINTS PR00474 Glutamate 5-kinase family signature 164 191 2.1E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 PRINTS PR00474 Glutamate 5-kinase family signature 58 72 2.1E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 PRINTS PR00474 Glutamate 5-kinase family signature 225 245 2.1E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 PRINTS PR00474 Glutamate 5-kinase family signature 132 153 2.1E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TL08_08195 f073f1da8f57579b72b5bc02ed4d1024 378 PRINTS PR00474 Glutamate 5-kinase family signature 92 120 2.1E-50 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TL08_10745 cc2716b9418721c912b091bfa6e5078a 153 SMART SM00240 72 122 2.0E-16 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TL08_10745 cc2716b9418721c912b091bfa6e5078a 153 SUPERFAMILY SSF49879 33 143 1.91E-32 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TL08_10745 cc2716b9418721c912b091bfa6e5078a 153 Pfam PF00498 FHA domain 74 136 2.5E-19 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TL08_10745 cc2716b9418721c912b091bfa6e5078a 153 Gene3D G3DSA:2.60.200.20 20 147 4.2E-42 T 12-10-2018 TL08_14755 41d0933c17eae038100470e2b41ff53c 305 SUPERFAMILY SSF51569 4 297 1.99E-75 T 12-10-2018 TL08_14755 41d0933c17eae038100470e2b41ff53c 305 PIRSF PIRSF001365 5 304 1.3E-68 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_14755 41d0933c17eae038100470e2b41ff53c 305 Pfam PF00701 Dihydrodipicolinate synthetase family 30 294 1.1E-44 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_14755 41d0933c17eae038100470e2b41ff53c 305 Gene3D G3DSA:3.20.20.70 2 299 4.2E-79 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_14755 41d0933c17eae038100470e2b41ff53c 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 47 68 1.0E-6 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_14755 41d0933c17eae038100470e2b41ff53c 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 115 131 1.0E-6 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_14755 41d0933c17eae038100470e2b41ff53c 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 1.0E-6 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_14755 41d0933c17eae038100470e2b41ff53c 305 SMART SM01130 7 299 3.4E-83 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 12-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 3.5E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 3.5E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 3.5E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 3.5E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 3.5E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 SUPERFAMILY SSF53098 2 156 9.86E-45 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 Gene3D G3DSA:3.30.420.10 1 160 7.1E-49 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 45.873 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 154 9.0E-36 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TL08_10510 13a4cd1d6e1d1f6ee1604a1f766e581f 305 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 7.5E-56 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TL08_04025 abd15d55f504888259306f7f327c4951 289 Gene3D G3DSA:1.10.10.60 53 104 2.8E-11 T 12-10-2018 TL08_04025 abd15d55f504888259306f7f327c4951 289 SUPERFAMILY SSF46689 3 53 8.51E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_04025 abd15d55f504888259306f7f327c4951 289 SMART SM00342 19 102 6.1E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_04025 abd15d55f504888259306f7f327c4951 289 SUPERFAMILY SSF55136 126 287 1.73E-18 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily TL08_04025 abd15d55f504888259306f7f327c4951 289 Pfam PF06445 GyrI-like small molecule binding domain 126 285 1.4E-19 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain TL08_04025 abd15d55f504888259306f7f327c4951 289 Gene3D G3DSA:3.20.80.10 126 287 5.2E-26 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily TL08_04025 abd15d55f504888259306f7f327c4951 289 Pfam PF12833 Helix-turn-helix domain 26 103 4.8E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_04025 abd15d55f504888259306f7f327c4951 289 SMART SM00871 126 286 4.7E-17 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding TL08_04025 abd15d55f504888259306f7f327c4951 289 Gene3D G3DSA:1.10.10.60 2 52 1.1E-10 T 12-10-2018 TL08_04025 abd15d55f504888259306f7f327c4951 289 SUPERFAMILY SSF46689 55 104 9.86E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_24935 821ff05ab09a966201cd9c11d3717ac3 105 SUPERFAMILY SSF140453 6 98 3.92E-20 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_24935 821ff05ab09a966201cd9c11d3717ac3 105 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 7 93 9.3E-19 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like TL08_24935 821ff05ab09a966201cd9c11d3717ac3 105 Gene3D G3DSA:1.10.287.1060 6 104 1.7E-20 T 12-10-2018 TL08_24935 821ff05ab09a966201cd9c11d3717ac3 105 Pfam PF06013 Proteins of 100 residues with WXG 7 88 2.1E-17 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like TL08_17980 326487283408d94b6553c9adf1aeaaa2 375 Pfam PF00589 Phage integrase family 168 334 1.6E-43 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_17980 326487283408d94b6553c9adf1aeaaa2 375 SUPERFAMILY SSF56349 158 348 1.62E-51 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_17980 326487283408d94b6553c9adf1aeaaa2 375 Gene3D G3DSA:1.10.443.10 163 344 5.7E-58 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TL08_17980 326487283408d94b6553c9adf1aeaaa2 375 SUPERFAMILY SSF47823 53 148 4.32E-14 T 12-10-2018 TL08_17980 326487283408d94b6553c9adf1aeaaa2 375 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 54 142 1.5E-19 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TL08_17980 326487283408d94b6553c9adf1aeaaa2 375 Gene3D G3DSA:1.10.150.130 50 151 1.7E-15 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_17980 326487283408d94b6553c9adf1aeaaa2 375 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 52 350 53.159 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD TL08_24180 f495fc100427e3b39ac2bef4d4109763 770 SUPERFAMILY SSF82866 540 728 2.22E-21 T 12-10-2018 TL08_24180 f495fc100427e3b39ac2bef4d4109763 770 SUPERFAMILY SSF82866 130 355 7.46E-30 T 12-10-2018 TL08_24180 f495fc100427e3b39ac2bef4d4109763 770 Pfam PF03176 MMPL family 64 388 9.4E-41 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TL08_24180 f495fc100427e3b39ac2bef4d4109763 770 Pfam PF03176 MMPL family 526 736 3.0E-27 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TL08_20220 75c7de70633abbefe789764ec75ad5b1 543 SMART SM00382 344 516 4.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_20220 75c7de70633abbefe789764ec75ad5b1 543 Gene3D G3DSA:1.20.1560.10 6 303 5.6E-17 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_20220 75c7de70633abbefe789764ec75ad5b1 543 Gene3D G3DSA:3.40.50.300 309 540 3.7E-64 T 12-10-2018 TL08_20220 75c7de70633abbefe789764ec75ad5b1 543 SUPERFAMILY SSF52540 312 538 1.26E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20220 75c7de70633abbefe789764ec75ad5b1 543 SUPERFAMILY SSF90123 12 307 8.11E-30 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_20220 75c7de70633abbefe789764ec75ad5b1 543 ProSitePatterns PS00211 ABC transporters family signature. 442 456 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_20220 75c7de70633abbefe789764ec75ad5b1 543 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 11 499 8.1E-126 T 12-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 TL08_20220 75c7de70633abbefe789764ec75ad5b1 543 Pfam PF00005 ABC transporter 335 469 1.1E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_08855 8bc4c76cc4a6a986e10f303956c37268 333 Pfam PF00589 Phage integrase family 146 318 2.9E-39 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_08855 8bc4c76cc4a6a986e10f303956c37268 333 SUPERFAMILY SSF56349 139 331 2.47E-45 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_08855 8bc4c76cc4a6a986e10f303956c37268 333 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 41 120 1.5E-15 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TL08_08855 8bc4c76cc4a6a986e10f303956c37268 333 SUPERFAMILY SSF47823 41 130 3.53E-10 T 12-10-2018 TL08_08855 8bc4c76cc4a6a986e10f303956c37268 333 Gene3D G3DSA:1.10.443.10 145 327 6.9E-54 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TL08_08855 8bc4c76cc4a6a986e10f303956c37268 333 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 37 333 50.863 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD TL08_08855 8bc4c76cc4a6a986e10f303956c37268 333 Gene3D G3DSA:1.10.150.130 40 130 4.6E-15 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_18055 4cda46415213e70b6ea8bf116d51ea1b 361 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 25 251 4.7E-30 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TL08_18055 4cda46415213e70b6ea8bf116d51ea1b 361 Pfam PF13242 HAD-hyrolase-like 204 275 2.0E-13 T 12-10-2018 TL08_18055 4cda46415213e70b6ea8bf116d51ea1b 361 Gene3D G3DSA:3.40.50.1000 89 204 3.5E-71 T 12-10-2018 IPR023214 HAD superfamily TL08_18055 4cda46415213e70b6ea8bf116d51ea1b 361 Gene3D G3DSA:3.40.50.1000 22 254 3.5E-71 T 12-10-2018 IPR023214 HAD superfamily TL08_18055 4cda46415213e70b6ea8bf116d51ea1b 361 Pfam PF13344 Haloacid dehalogenase-like hydrolase 24 124 5.6E-19 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TL08_18055 4cda46415213e70b6ea8bf116d51ea1b 361 SUPERFAMILY SSF56784 20 274 1.12E-49 T 12-10-2018 IPR036412 HAD-like superfamily TL08_18055 4cda46415213e70b6ea8bf116d51ea1b 361 PIRSF PIRSF000915 4 283 5.9E-56 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TL08_03400 339e5bdc229a671ed37ce308e841c5d1 261 SUPERFAMILY SSF54593 140 258 1.1E-12 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03400 339e5bdc229a671ed37ce308e841c5d1 261 SUPERFAMILY SSF54593 1 137 4.34E-13 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03400 339e5bdc229a671ed37ce308e841c5d1 261 Gene3D G3DSA:3.10.180.10 138 261 1.3E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03400 339e5bdc229a671ed37ce308e841c5d1 261 Gene3D G3DSA:3.10.180.10 3 132 1.9E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 SMART SM00450 144 271 1.6E-20 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 SMART SM00450 8 122 3.9E-22 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 Pfam PF00581 Rhodanese-like domain 9 118 3.1E-15 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 Pfam PF00581 Rhodanese-like domain 149 266 1.6E-16 T 12-10-2018 IPR001763 Rhodanese-like domain TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 SUPERFAMILY SSF52821 5 140 1.57E-35 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 SUPERFAMILY SSF52821 149 274 1.44E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 Gene3D G3DSA:3.40.250.10 143 275 9.3E-41 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 ProSitePatterns PS00380 Rhodanese signature 1. 34 45 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TL08_25935 f7bee69536bfc24bad9f5711201c0416 282 Gene3D G3DSA:3.40.250.10 1 142 3.3E-41 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TL08_15130 8a9d9b18d594e4fbe74d22e9ce928bf7 103 Pfam PF01022 Bacterial regulatory protein, arsR family 11 55 2.2E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_15130 8a9d9b18d594e4fbe74d22e9ce928bf7 103 SMART SM00418 3 81 9.6E-26 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_15130 8a9d9b18d594e4fbe74d22e9ce928bf7 103 SUPERFAMILY SSF46785 3 96 4.66E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_15130 8a9d9b18d594e4fbe74d22e9ce928bf7 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 8.9E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_15130 8a9d9b18d594e4fbe74d22e9ce928bf7 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 8.9E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_15130 8a9d9b18d594e4fbe74d22e9ce928bf7 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 8.9E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_15130 8a9d9b18d594e4fbe74d22e9ce928bf7 103 Gene3D G3DSA:1.10.10.10 1 101 1.2E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26550 47e6fb5229177032962dea69e9838b31 253 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 198 221 0.0016 T 12-10-2018 TL08_26550 47e6fb5229177032962dea69e9838b31 253 SUPERFAMILY SSF49319 41 169 7.19E-15 T 12-10-2018 IPR027273 Neocarzinostatin-like TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 14 295 9.6E-99 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 SUPERFAMILY SSF53328 96 295 6.8E-56 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 PIRSF PIRSF036480 7 295 3.1E-107 T 12-10-2018 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 Gene3D G3DSA:3.40.50.170 95 295 3.2E-66 T 12-10-2018 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 Gene3D G3DSA:3.30.70.260 6 94 1.0E-22 T 12-10-2018 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 Pfam PF00551 Formyl transferase 96 275 4.8E-38 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 SUPERFAMILY SSF55021 9 87 1.33E-13 T 12-10-2018 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 44 56 1.2E-56 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 96 118 1.2E-56 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 12 38 1.2E-56 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 247 269 1.2E-56 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 118 145 1.2E-56 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 269 294 1.2E-56 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TL08_02205 e9b6a6bed372fa94551054c9cd3b39c1 295 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 7 295 46.596 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TL08_02430 2c3560e1d0b4eff2b512323ecef71f5a 210 SUPERFAMILY SSF53254 6 197 3.53E-37 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_02430 2c3560e1d0b4eff2b512323ecef71f5a 210 Gene3D G3DSA:3.40.50.1240 2 198 7.2E-30 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_02430 2c3560e1d0b4eff2b512323ecef71f5a 210 SMART SM00855 6 158 1.8E-16 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_02430 2c3560e1d0b4eff2b512323ecef71f5a 210 PIRSF PIRSF000709 1 76 0.0076 T 12-10-2018 TL08_02430 2c3560e1d0b4eff2b512323ecef71f5a 210 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 192 2.4E-35 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_03265 8d8cf9c95ff57c50af2481f91d4de80b 204 Gene3D G3DSA:3.40.50.10420 13 201 2.2E-38 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TL08_03265 8d8cf9c95ff57c50af2481f91d4de80b 204 SUPERFAMILY SSF100950 14 198 4.05E-39 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_03265 8d8cf9c95ff57c50af2481f91d4de80b 204 PIRSF PIRSF006806 10 197 7.8E-35 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TL08_03265 8d8cf9c95ff57c50af2481f91d4de80b 204 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 15 194 7.5E-40 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TL08_03265 8d8cf9c95ff57c50af2481f91d4de80b 204 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 15 194 1.8E-33 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TL08_08690 37a52b6569b8fad46e6d185910c97593 902 SUPERFAMILY SSF55729 35 177 2.48E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_08690 37a52b6569b8fad46e6d185910c97593 902 SMART SM00881 214 309 1.1E-32 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Gene3D G3DSA:3.40.50.261 340 499 4.0E-49 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 SUPERFAMILY SSF52210 340 499 2.62E-34 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 SUPERFAMILY SSF51735 209 344 1.46E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Pfam PF00583 Acetyltransferase (GNAT) family 69 172 4.0E-10 T 12-10-2018 IPR000182 GNAT domain TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 363 495 9.4E-43 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TL08_08690 37a52b6569b8fad46e6d185910c97593 902 SUPERFAMILY SSF52210 502 648 3.01E-17 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Gene3D G3DSA:3.40.50.261 532 655 5.1E-16 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Pfam PF13380 CoA binding domain 218 344 3.1E-23 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Gene3D G3DSA:3.40.630.30 29 212 2.2E-47 T 12-10-2018 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 SUPERFAMILY SSF56059 687 876 2.42E-22 T 12-10-2018 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Gene3D G3DSA:3.40.50.720 213 338 5.6E-43 T 12-10-2018 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Gene3D G3DSA:3.30.470.20 684 886 4.7E-56 T 12-10-2018 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Gene3D G3DSA:3.30.1490.20 702 772 4.7E-56 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TL08_08690 37a52b6569b8fad46e6d185910c97593 902 Pfam PF13549 ATP-grasp domain 683 888 5.5E-51 T 12-10-2018 TL08_00855 ca3194091782ca7dd488f75eec1d1bcb 537 Gene3D G3DSA:3.20.20.30 8 314 9.4E-57 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_00855 ca3194091782ca7dd488f75eec1d1bcb 537 Pfam PF00296 Luciferase-like monooxygenase 11 235 8.0E-42 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_00855 ca3194091782ca7dd488f75eec1d1bcb 537 Gene3D G3DSA:1.20.120.520 372 536 1.0E-29 T 12-10-2018 TL08_00855 ca3194091782ca7dd488f75eec1d1bcb 537 Pfam PF01814 Hemerythrin HHE cation binding domain 385 528 1.6E-16 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TL08_00855 ca3194091782ca7dd488f75eec1d1bcb 537 SUPERFAMILY SSF51679 7 289 1.03E-53 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_12390 a5ca997bb4445d376510d2556fcf6af7 414 Gene3D G3DSA:1.20.58.1130 55 245 3.3E-14 T 12-10-2018 TL08_12390 a5ca997bb4445d376510d2556fcf6af7 414 Gene3D G3DSA:1.20.1420.30 60 351 3.3E-14 T 12-10-2018 TL08_12390 a5ca997bb4445d376510d2556fcf6af7 414 Pfam PF01699 Sodium/calcium exchanger protein 214 356 1.3E-8 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TL08_12390 a5ca997bb4445d376510d2556fcf6af7 414 Pfam PF01699 Sodium/calcium exchanger protein 32 182 1.6E-12 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TL08_14450 043983500cdf4a370650eb3d8b09a85c 49 SUPERFAMILY SSF54862 2 41 2.01E-7 T 12-10-2018 TL08_14450 043983500cdf4a370650eb3d8b09a85c 49 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 8 46 4.2E-5 T 12-10-2018 TL08_14450 043983500cdf4a370650eb3d8b09a85c 49 Gene3D G3DSA:3.30.70.20 1 49 2.1E-9 T 12-10-2018 TL08_17190 240f9421bc06c6659472c40311d922c4 1113 Gene3D G3DSA:2.60.120.260 200 370 0.0 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_17190 240f9421bc06c6659472c40311d922c4 1113 PIRSF PIRSF010631 60 1113 5.2E-295 T 12-10-2018 IPR016007 Alpha-L-rhamnosidase TL08_17190 240f9421bc06c6659472c40311d922c4 1113 Gene3D G3DSA:2.60.40.10 70 181 3.9E-35 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_17190 240f9421bc06c6659472c40311d922c4 1113 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 572 671 1.1E-28 T 12-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain TL08_17190 240f9421bc06c6659472c40311d922c4 1113 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 676 1009 3.0E-95 T 12-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain TL08_17190 240f9421bc06c6659472c40311d922c4 1113 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 389 557 5.5E-55 T 12-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal TL08_17190 240f9421bc06c6659472c40311d922c4 1113 SUPERFAMILY SSF48208 677 1077 1.02E-36 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_17190 240f9421bc06c6659472c40311d922c4 1113 Gene3D G3DSA:1.50.10.10 187 1108 0.0 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_17190 240f9421bc06c6659472c40311d922c4 1113 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 1011 1082 2.4E-18 T 12-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain TL08_17190 240f9421bc06c6659472c40311d922c4 1113 SUPERFAMILY SSF49785 330 464 2.21E-6 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 Hamap MF_01987 Ribokinase [rbsK]. 5 300 24.259 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 Pfam PF00294 pfkB family carbohydrate kinase 5 294 3.2E-67 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 Gene3D G3DSA:3.40.1190.20 1 299 2.0E-96 T 12-10-2018 IPR029056 Ribokinase-like TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 SUPERFAMILY SSF53613 4 297 7.64E-80 T 12-10-2018 IPR029056 Ribokinase-like TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 PRINTS PR00990 Ribokinase signature 175 190 8.0E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 PRINTS PR00990 Ribokinase signature 217 228 8.0E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 PRINTS PR00990 Ribokinase signature 107 120 8.0E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 PRINTS PR00990 Ribokinase signature 9 30 8.0E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TL08_26965 4b143598d0698cc8a06c5c483af9d647 300 PRINTS PR00990 Ribokinase signature 36 55 8.0E-32 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TL08_02000 26a2c51928c8fbf138fa9da8938ca150 130 Gene3D G3DSA:2.60.120.10 1 115 5.9E-43 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_02000 26a2c51928c8fbf138fa9da8938ca150 130 Pfam PF06339 Ectoine synthase 2 125 2.2E-56 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 TL08_02000 26a2c51928c8fbf138fa9da8938ca150 130 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 1.0E-38 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 TL08_02000 26a2c51928c8fbf138fa9da8938ca150 130 SUPERFAMILY SSF51182 18 125 5.24E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_02000 26a2c51928c8fbf138fa9da8938ca150 130 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 36.429 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 TL08_22605 3f6931869345c6ab7ad56f5f6abe9454 163 SUPERFAMILY SSF51182 26 148 1.46E-28 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_22605 3f6931869345c6ab7ad56f5f6abe9454 163 Pfam PF05995 Cysteine dioxygenase type I 12 148 1.5E-24 T 12-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 TL08_22605 3f6931869345c6ab7ad56f5f6abe9454 163 Gene3D G3DSA:2.60.120.10 9 155 1.9E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_06070 bf6170d322e194e78781412d0c37671b 503 Gene3D G3DSA:3.30.750.24 402 496 1.4E-27 T 12-10-2018 IPR036513 STAS domain superfamily TL08_06070 bf6170d322e194e78781412d0c37671b 503 Pfam PF00916 Sulfate permease family 178 345 1.4E-25 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 TL08_06070 bf6170d322e194e78781412d0c37671b 503 Pfam PF00916 Sulfate permease family 31 155 1.2E-19 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 TL08_06070 bf6170d322e194e78781412d0c37671b 503 SUPERFAMILY SSF52091 410 491 7.85E-13 T 12-10-2018 IPR036513 STAS domain superfamily TL08_06070 bf6170d322e194e78781412d0c37671b 503 Pfam PF01740 STAS domain 412 489 3.8E-7 T 12-10-2018 IPR002645 STAS domain TL08_02370 99011bd79e9976fd7388c42cb10c6944 230 SMART SM00554 132 229 1.3E-27 T 12-10-2018 IPR000782 FAS1 domain TL08_02370 99011bd79e9976fd7388c42cb10c6944 230 SUPERFAMILY SSF82153 94 229 1.83E-29 T 12-10-2018 IPR036378 FAS1 domain superfamily TL08_02370 99011bd79e9976fd7388c42cb10c6944 230 Gene3D G3DSA:2.30.180.10 72 230 4.9E-39 T 12-10-2018 IPR036378 FAS1 domain superfamily TL08_02370 99011bd79e9976fd7388c42cb10c6944 230 Pfam PF02469 Fasciclin domain 108 228 8.8E-27 T 12-10-2018 IPR000782 FAS1 domain TL08_02865 03dcb7e21a2d78e926809c2e47e0baa0 413 Gene3D G3DSA:3.90.1150.10 40 405 2.8E-135 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_02865 03dcb7e21a2d78e926809c2e47e0baa0 413 SUPERFAMILY SSF53383 17 411 2.42E-116 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_02865 03dcb7e21a2d78e926809c2e47e0baa0 413 Pfam PF00155 Aminotransferase class I and II 46 403 1.1E-74 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_02865 03dcb7e21a2d78e926809c2e47e0baa0 413 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 250 263 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TL08_02865 03dcb7e21a2d78e926809c2e47e0baa0 413 Gene3D G3DSA:3.40.640.10 78 300 2.8E-135 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 817 833 4.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 726 751 4.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 702 715 4.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 649 664 4.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 847 860 4.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 785 796 4.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 672 695 4.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 763 774 4.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 626 648 4.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 12 180 6.9E-55 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 SMART SM00475 11 271 1.5E-135 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Pfam PF01612 3'-5' exonuclease 352 448 1.6E-4 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Gene3D G3DSA:3.40.50.1010 13 287 1.3E-94 T 12-10-2018 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Gene3D G3DSA:1.20.1060.10 515 629 4.7E-30 T 12-10-2018 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 SMART SM00482 657 864 2.1E-107 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 SMART SM00474 312 490 3.5E-14 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Pfam PF00476 DNA polymerase family A 523 897 8.1E-141 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Gene3D G3DSA:1.10.150.20 681 824 5.3E-101 T 12-10-2018 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 SUPERFAMILY SSF53098 319 489 1.97E-26 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 TIGRFAM TIGR00593 pola: DNA polymerase I 13 899 6.6E-303 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Gene3D G3DSA:3.30.70.370 635 896 5.3E-101 T 12-10-2018 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 182 275 1.4E-26 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 SMART SM00279 183 218 2.4E-16 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Gene3D G3DSA:3.30.420.10 332 513 1.6E-30 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 SUPERFAMILY SSF88723 9 180 2.28E-53 T 12-10-2018 IPR029060 PIN-like domain superfamily TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 ProSitePatterns PS00447 DNA polymerase family A signature. 726 745 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 SUPERFAMILY SSF56672 496 899 1.22E-135 T 12-10-2018 TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 SUPERFAMILY SSF47807 181 294 1.44E-28 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TL08_10220 223c291c453d2945b1c34e7bc0265e80 901 Gene3D G3DSA:1.10.150.20 184 256 1.3E-94 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2155 2170 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 ProSitePatterns PS00455 Putative AMP-binding domain signature. 720 731 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:3.40.50.12780 572 969 1.3E-113 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:3.40.50.12780 1621 2018 5.6E-65 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Pfam PF00550 Phosphopantetheine attachment site 19 78 1.1E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Pfam PF00550 Phosphopantetheine attachment site 2133 2193 6.0E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Pfam PF00550 Phosphopantetheine attachment site 1089 1148 1.3E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SMART SM00823 Phosphopantetheine attachment site 2131 2188 0.0098 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SMART SM00823 Phosphopantetheine attachment site 14 71 0.045 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SUPERFAMILY SSF56801 1627 2143 1.96E-77 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SUPERFAMILY SSF52777 1354 1597 7.23E-42 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:3.30.559.30 293 571 2.7E-70 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:3.30.559.30 1351 1600 5.0E-80 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:1.10.1200.10 6 85 3.4E-15 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SUPERFAMILY SSF52777 293 543 1.22E-35 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Pfam PF00501 AMP-binding enzyme 579 976 2.3E-91 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Pfam PF00501 AMP-binding enzyme 1633 2018 1.8E-43 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SUPERFAMILY SSF47336 10 124 1.83E-11 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SUPERFAMILY SSF52777 1169 1366 9.56E-26 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 600 1000 2.5E-115 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SUPERFAMILY SSF56801 555 1099 1.01E-133 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:3.30.300.30 970 1074 2.2E-24 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SUPERFAMILY SSF47336 2126 2193 4.45E-13 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SUPERFAMILY SSF47336 1080 1151 1.2E-12 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 SUPERFAMILY SSF52777 112 306 6.56E-22 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:1.10.1200.10 2124 2201 1.2E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Pfam PF00668 Condensation domain 1207 1594 2.8E-27 T 12-10-2018 IPR001242 Condensation domain TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Pfam PF00668 Condensation domain 141 522 1.8E-25 T 12-10-2018 IPR001242 Condensation domain TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:3.30.559.10 1167 1347 1.2E-51 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:3.30.559.10 109 288 1.0E-47 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:3.30.300.30 2023 2120 1.3E-14 T 12-10-2018 TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Gene3D G3DSA:1.10.1200.10 1075 1162 1.5E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Pfam PF13193 AMP-binding enzyme C-terminal domain 985 1057 1.7E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_14440 2b34315ca208e02082e2808003b7eb50 2211 Pfam PF13193 AMP-binding enzyme C-terminal domain 2035 2105 1.7E-6 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_25545 b76d728c9e4698aa9afa8513118c97f4 754 Pfam PF13538 UvrD-like helicase C-terminal domain 691 738 7.9E-7 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain TL08_25545 b76d728c9e4698aa9afa8513118c97f4 754 Gene3D G3DSA:3.40.50.300 494 603 5.1E-6 T 12-10-2018 TL08_25545 b76d728c9e4698aa9afa8513118c97f4 754 SUPERFAMILY SSF52540 175 743 1.05E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25545 b76d728c9e4698aa9afa8513118c97f4 754 Gene3D G3DSA:3.40.50.300 172 253 1.0E-9 T 12-10-2018 TL08_25545 b76d728c9e4698aa9afa8513118c97f4 754 Gene3D G3DSA:3.40.50.300 604 753 3.5E-10 T 12-10-2018 TL08_12600 4b8198de59bea591634243966ad60c78 515 Pfam PF00501 AMP-binding enzyme 10 414 2.2E-105 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_12600 4b8198de59bea591634243966ad60c78 515 Gene3D G3DSA:3.40.50.12780 1 407 2.2E-117 T 12-10-2018 TL08_12600 4b8198de59bea591634243966ad60c78 515 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 499 1.0E-18 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_12600 4b8198de59bea591634243966ad60c78 515 SUPERFAMILY SSF56801 4 511 1.83E-151 T 12-10-2018 TL08_12600 4b8198de59bea591634243966ad60c78 515 Gene3D G3DSA:3.30.300.310 410 514 1.1E-29 T 12-10-2018 TL08_12600 4b8198de59bea591634243966ad60c78 515 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_21310 e169c42d6a94090699425b003d40fcb9 320 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 262 37.963 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TL08_21310 e169c42d6a94090699425b003d40fcb9 320 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 261 4.2E-74 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TL08_21310 e169c42d6a94090699425b003d40fcb9 320 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 261 3.9E-75 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TL08_21310 e169c42d6a94090699425b003d40fcb9 320 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TL08_21310 e169c42d6a94090699425b003d40fcb9 320 Gene3D G3DSA:3.40.1180.10 4 256 8.4E-96 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TL08_21310 e169c42d6a94090699425b003d40fcb9 320 SUPERFAMILY SSF64005 34 257 3.92E-84 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 100 728 43.918 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 SUPERFAMILY SSF51011 622 728 1.92E-31 T 12-10-2018 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 SUPERFAMILY SSF81296 18 113 1.82E-19 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 PIRSF PIRSF000463 10 729 1.3E-280 T 12-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 124 210 2.2E-20 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 Gene3D G3DSA:3.20.20.80 226 620 3.2E-171 T 12-10-2018 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 Pfam PF00128 Alpha amylase, catalytic domain 274 342 2.5E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 Gene3D G3DSA:2.60.40.1180 621 728 1.5E-38 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 Gene3D G3DSA:2.60.40.10 6 225 2.1E-73 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 SUPERFAMILY SSF81296 141 199 6.16E-9 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 108 725 1.4E-276 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 SMART SM00642 253 611 1.5E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 626 727 4.8E-21 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TL08_07525 e379921daad3c7bb4f23f5f4cebfa083 729 SUPERFAMILY SSF51445 183 614 2.16E-110 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_20725 8a68ee09fa590cc3691905e98f000fbf 493 PIRSF PIRSF000538 363 493 3.1E-11 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TL08_20725 8a68ee09fa590cc3691905e98f000fbf 493 PIRSF PIRSF000538 4 295 2.9E-28 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TL08_20725 8a68ee09fa590cc3691905e98f000fbf 493 SUPERFAMILY SSF53067 4 247 1.94E-45 T 12-10-2018 TL08_20725 8a68ee09fa590cc3691905e98f000fbf 493 Gene3D G3DSA:3.30.420.40 239 488 4.3E-98 T 12-10-2018 TL08_20725 8a68ee09fa590cc3691905e98f000fbf 493 SUPERFAMILY SSF53067 254 489 1.53E-34 T 12-10-2018 TL08_20725 8a68ee09fa590cc3691905e98f000fbf 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 446 4.7E-34 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TL08_20725 8a68ee09fa590cc3691905e98f000fbf 493 Gene3D G3DSA:3.30.420.40 1 238 1.3E-80 T 12-10-2018 TL08_20725 8a68ee09fa590cc3691905e98f000fbf 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 245 1.7E-29 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TL08_02995 6858191f3d22d8e59e1fc384d27400a8 99 Gene3D G3DSA:3.30.70.330 5 96 4.6E-31 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TL08_02995 6858191f3d22d8e59e1fc384d27400a8 99 Pfam PF00276 Ribosomal protein L23 7 89 9.2E-32 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TL08_02995 6858191f3d22d8e59e1fc384d27400a8 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 6 96 21.335 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TL08_02995 6858191f3d22d8e59e1fc384d27400a8 99 SUPERFAMILY SSF54189 4 92 2.27E-31 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_18525 6e75f57246800b2ae4694f613aecfe5b 329 Gene3D G3DSA:1.10.600.10 6 325 3.2E-68 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_18525 6e75f57246800b2ae4694f613aecfe5b 329 SUPERFAMILY SSF48576 25 323 3.78E-57 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_18525 6e75f57246800b2ae4694f613aecfe5b 329 Pfam PF00348 Polyprenyl synthetase 33 280 1.5E-39 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 PRINTS PR00173 Glutamate-aspartate symporter signature 347 366 3.1E-28 T 12-10-2018 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 PRINTS PR00173 Glutamate-aspartate symporter signature 373 393 3.1E-28 T 12-10-2018 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 PRINTS PR00173 Glutamate-aspartate symporter signature 312 338 3.1E-28 T 12-10-2018 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 PRINTS PR00173 Glutamate-aspartate symporter signature 95 120 3.1E-28 T 12-10-2018 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 PRINTS PR00173 Glutamate-aspartate symporter signature 19 39 3.1E-28 T 12-10-2018 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 PRINTS PR00173 Glutamate-aspartate symporter signature 61 81 3.1E-28 T 12-10-2018 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 PRINTS PR00173 Glutamate-aspartate symporter signature 209 228 3.1E-28 T 12-10-2018 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 Gene3D G3DSA:1.10.3860.10 9 436 4.1E-113 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 SUPERFAMILY SSF118215 21 419 2.22E-95 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TL08_23740 0abb04e360c4fdbef9e57740a2f7ecb1 478 Pfam PF00375 Sodium:dicarboxylate symporter family 21 418 1.7E-103 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TL08_23250 f329bddc985d1a0e791ef183d38a81fd 152 Gene3D G3DSA:3.40.50.1000 15 146 1.7E-29 T 12-10-2018 IPR023214 HAD superfamily TL08_23250 f329bddc985d1a0e791ef183d38a81fd 152 Pfam PF13419 Haloacid dehalogenase-like hydrolase 69 123 1.2E-7 T 12-10-2018 TL08_23250 f329bddc985d1a0e791ef183d38a81fd 152 SUPERFAMILY SSF56784 21 137 5.46E-24 T 12-10-2018 IPR036412 HAD-like superfamily TL08_23250 f329bddc985d1a0e791ef183d38a81fd 152 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 36 127 4.5E-16 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_21345 75fe5dc05baf6254c2948d6d24373441 257 SUPERFAMILY SSF50249 1 79 1.08E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_21345 75fe5dc05baf6254c2948d6d24373441 257 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 26.479 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TL08_21345 75fe5dc05baf6254c2948d6d24373441 257 Pfam PF02565 Recombination protein O C terminal 85 238 2.1E-34 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TL08_21345 75fe5dc05baf6254c2948d6d24373441 257 Pfam PF11967 Recombination protein O N terminal 1 79 3.1E-26 T 12-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal TL08_21345 75fe5dc05baf6254c2948d6d24373441 257 SUPERFAMILY SSF57863 82 232 6.02E-41 T 12-10-2018 IPR037278 ARFGAP/RecO-like zinc finger TL08_21345 75fe5dc05baf6254c2948d6d24373441 257 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 238 2.0E-36 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TL08_21345 75fe5dc05baf6254c2948d6d24373441 257 Gene3D G3DSA:2.40.50.140 2 81 7.3E-28 T 12-10-2018 TL08_18480 e43f9588b2147b5e2b4833f8e4608b14 396 Gene3D G3DSA:3.30.413.10 273 373 1.5E-36 T 12-10-2018 TL08_18480 e43f9588b2147b5e2b4833f8e4608b14 396 SUPERFAMILY SSF51717 48 220 9.42E-9 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_18480 e43f9588b2147b5e2b4833f8e4608b14 396 Pfam PF04551 GcpE protein 22 362 4.4E-134 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TL08_18480 e43f9588b2147b5e2b4833f8e4608b14 396 Gene3D G3DSA:3.20.20.20 14 272 2.2E-104 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_18480 e43f9588b2147b5e2b4833f8e4608b14 396 SUPERFAMILY SSF56014 277 363 5.67E-12 T 12-10-2018 TL08_18480 e43f9588b2147b5e2b4833f8e4608b14 396 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 19 361 2.0E-126 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TL08_18480 e43f9588b2147b5e2b4833f8e4608b14 396 PIRSF PIRSF004640 13 374 8.9E-144 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TL08_18480 e43f9588b2147b5e2b4833f8e4608b14 396 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 17 368 33.102 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TL08_04030 847f5772ef0ffc9eeb42f21d5f60b62b 398 SUPERFAMILY SSF54593 31 385 1.06E-90 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_04030 847f5772ef0ffc9eeb42f21d5f60b62b 398 Gene3D G3DSA:3.10.180.10 194 398 3.2E-78 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_04030 847f5772ef0ffc9eeb42f21d5f60b62b 398 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 38 398 1.0E-128 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 TL08_04030 847f5772ef0ffc9eeb42f21d5f60b62b 398 Gene3D G3DSA:3.10.180.10 24 190 9.5E-51 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_04030 847f5772ef0ffc9eeb42f21d5f60b62b 398 PIRSF PIRSF009283 26 398 2.7E-131 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 TL08_04030 847f5772ef0ffc9eeb42f21d5f60b62b 398 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 40 149 1.0E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_04030 847f5772ef0ffc9eeb42f21d5f60b62b 398 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 209 352 7.5E-15 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_17175 4261210ab7de977cf039ea793940bfb8 273 Gene3D G3DSA:3.40.50.1820 11 264 2.3E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_17175 4261210ab7de977cf039ea793940bfb8 273 Pfam PF12697 Alpha/beta hydrolase family 30 254 2.0E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17175 4261210ab7de977cf039ea793940bfb8 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 2.9E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17175 4261210ab7de977cf039ea793940bfb8 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 2.9E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17175 4261210ab7de977cf039ea793940bfb8 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.9E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17175 4261210ab7de977cf039ea793940bfb8 273 SUPERFAMILY SSF53474 16 264 9.51E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21930 e1b1b004010a2cb08ab66a370ebd525b 279 SUPERFAMILY SSF51735 2 272 1.06E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_21930 e1b1b004010a2cb08ab66a370ebd525b 279 Gene3D G3DSA:3.40.50.720 2 279 7.8E-62 T 12-10-2018 TL08_21930 e1b1b004010a2cb08ab66a370ebd525b 279 Pfam PF13460 NAD(P)H-binding 6 178 5.3E-20 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 195 27.912 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 SUPERFAMILY SSF46929 148 196 1.7E-7 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 Pfam PF14520 Helix-hairpin-helix domain 71 129 7.9E-15 T 12-10-2018 TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 Gene3D G3DSA:1.10.150.20 67 135 3.4E-23 T 12-10-2018 TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 SMART SM00278 72 91 41.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 SMART SM00278 107 126 0.51 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 177 4.6E-38 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 SUPERFAMILY SSF50249 1 62 8.57E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 Gene3D G3DSA:2.40.50.140 1 64 1.5E-23 T 12-10-2018 TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 Gene3D G3DSA:1.10.8.10 136 198 1.4E-17 T 12-10-2018 TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 Pfam PF01330 RuvA N terminal domain 1 61 1.0E-16 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 SUPERFAMILY SSF47781 64 132 1.97E-19 T 12-10-2018 IPR010994 RuvA domain 2-like TL08_10515 cac6322c97d595d34f3480c5b2d5ac62 198 Pfam PF07499 RuvA, C-terminal domain 150 194 7.9E-9 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 TL08_07545 627fe98921b72ca4b00de320e8065ddb 171 SUPERFAMILY SSF55811 17 145 2.3E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_07545 627fe98921b72ca4b00de320e8065ddb 171 PRINTS PR00502 NUDIX hydrolase family signature 60 75 5.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_07545 627fe98921b72ca4b00de320e8065ddb 171 PRINTS PR00502 NUDIX hydrolase family signature 46 60 5.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_07545 627fe98921b72ca4b00de320e8065ddb 171 Gene3D G3DSA:3.90.79.10 6 144 4.6E-28 T 12-10-2018 TL08_07545 627fe98921b72ca4b00de320e8065ddb 171 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_07545 627fe98921b72ca4b00de320e8065ddb 171 Pfam PF00293 NUDIX domain 25 134 2.1E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_08925 2288ee5ee373bd527a3c411f1ed94a94 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 273 3.3E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_08925 2288ee5ee373bd527a3c411f1ed94a94 284 SUPERFAMILY SSF161098 22 274 6.02E-50 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08925 2288ee5ee373bd527a3c411f1ed94a94 284 Gene3D G3DSA:1.10.3720.10 14 281 1.1E-48 T 12-10-2018 IPR035906 MetI-like superfamily TL08_17130 c424e57d99a199f672b9de30d1ba71fd 265 Gene3D G3DSA:3.40.50.1820 4 262 4.0E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_17130 c424e57d99a199f672b9de30d1ba71fd 265 Pfam PF12697 Alpha/beta hydrolase family 24 244 1.8E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17130 c424e57d99a199f672b9de30d1ba71fd 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 1.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17130 c424e57d99a199f672b9de30d1ba71fd 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17130 c424e57d99a199f672b9de30d1ba71fd 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 1.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17130 c424e57d99a199f672b9de30d1ba71fd 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 1.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17130 c424e57d99a199f672b9de30d1ba71fd 265 SUPERFAMILY SSF53474 5 262 1.17E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 89 104 3.4E-24 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 8 23 3.4E-24 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 49 61 3.4E-24 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 104 116 3.4E-24 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 117 132 3.4E-24 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 Gene3D G3DSA:2.40.100.10 1 160 2.7E-70 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 PIRSF PIRSF001467 1 163 8.3E-56 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 SUPERFAMILY SSF50891 1 158 1.33E-58 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 44 61 - T 12-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 TL08_00080 eedcdf69ffb4a0d3c4405c0c254e3517 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 1 158 5.1E-44 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_13485 3e2afdb68c4c10609bd5093cccbc0b6e 392 Pfam PF00881 Nitroreductase family 172 357 6.8E-11 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TL08_13485 3e2afdb68c4c10609bd5093cccbc0b6e 392 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 188 356 5.3E-30 T 12-10-2018 IPR020051 SagB-type dehydrogenase domain TL08_13485 3e2afdb68c4c10609bd5093cccbc0b6e 392 Gene3D G3DSA:3.40.109.10 139 371 1.1E-54 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_13485 3e2afdb68c4c10609bd5093cccbc0b6e 392 SUPERFAMILY SSF55469 166 361 7.07E-15 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_07975 e2226c9fd7c104564fb36667e537f3c9 405 Gene3D G3DSA:3.40.630.30 141 289 2.3E-36 T 12-10-2018 TL08_07975 e2226c9fd7c104564fb36667e537f3c9 405 Pfam PF13530 Sterol carrier protein domain 181 401 1.4E-46 T 12-10-2018 IPR025559 Enhanced intracellular survival protein domain TL08_07975 e2226c9fd7c104564fb36667e537f3c9 405 SUPERFAMILY SSF55718 299 402 1.73E-20 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TL08_07975 e2226c9fd7c104564fb36667e537f3c9 405 Hamap MF_01812 N-acetyltransferase Eis [eis]. 5 405 30.285 T 12-10-2018 IPR022902 N-acetyltransferase Eis TL08_07975 e2226c9fd7c104564fb36667e537f3c9 405 Gene3D G3DSA:3.30.1050.10 297 396 6.7E-28 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TL08_07975 e2226c9fd7c104564fb36667e537f3c9 405 Gene3D G3DSA:3.40.630.30 4 138 1.1E-28 T 12-10-2018 TL08_07975 e2226c9fd7c104564fb36667e537f3c9 405 Pfam PF13527 Acetyltransferase (GNAT) domain 8 132 6.3E-26 T 12-10-2018 TL08_07975 e2226c9fd7c104564fb36667e537f3c9 405 SUPERFAMILY SSF55729 9 298 3.45E-45 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_06195 a97ab191493fab4e6f83c3dd99f4900d 300 Gene3D G3DSA:3.40.50.1820 1 271 1.5E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06195 a97ab191493fab4e6f83c3dd99f4900d 300 SUPERFAMILY SSF53474 2 295 6.27E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06195 a97ab191493fab4e6f83c3dd99f4900d 300 Pfam PF12146 Serine aminopeptidase, S33 52 259 3.7E-13 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 TL08_07940 a0906212ac9c57938013846718450268 272 SUPERFAMILY SSF56281 8 231 4.06E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_07940 a0906212ac9c57938013846718450268 272 Pfam PF00753 Metallo-beta-lactamase superfamily 30 209 3.4E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_07940 a0906212ac9c57938013846718450268 272 Gene3D G3DSA:3.60.15.10 4 239 2.7E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_07940 a0906212ac9c57938013846718450268 272 SMART SM00849 27 218 1.6E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_11430 99296e76cd44e8460373152ac23883e9 369 SUPERFAMILY SSF56796 11 353 2.62E-101 T 12-10-2018 TL08_11430 99296e76cd44e8460373152ac23883e9 369 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 339 9.2E-108 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TL08_11430 99296e76cd44e8460373152ac23883e9 369 Gene3D G3DSA:3.40.50.1970 1 171 6.8E-58 T 12-10-2018 TL08_11430 99296e76cd44e8460373152ac23883e9 369 Pfam PF01761 3-dehydroquinate synthase 66 322 1.8E-93 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TL08_11430 99296e76cd44e8460373152ac23883e9 369 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 4 358 61.633 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TL08_11430 99296e76cd44e8460373152ac23883e9 369 PIRSF PIRSF001455 4 351 9.2E-100 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TL08_11430 99296e76cd44e8460373152ac23883e9 369 Gene3D G3DSA:1.20.1090.10 172 359 4.2E-69 T 12-10-2018 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Pfam PF13620 Carboxypeptidase regulatory-like domain 590 666 1.5E-10 T 12-10-2018 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Pfam PF13620 Carboxypeptidase regulatory-like domain 508 584 5.0E-13 T 12-10-2018 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Pfam PF13620 Carboxypeptidase regulatory-like domain 863 942 1.9E-8 T 12-10-2018 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Pfam PF11721 Di-glucose binding within endoplasmic reticulum 1331 1469 3.3E-19 T 12-10-2018 IPR021720 Malectin domain Reactome: R-HSA-532668|Reactome: R-HSA-6798695 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 SUPERFAMILY SSF49452 585 665 6.87E-10 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 431 441 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Pfam PF00082 Subtilase family 200 471 1.1E-40 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 SUPERFAMILY SSF49452 503 583 2.35E-11 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 SUPERFAMILY SSF52743 181 498 1.26E-60 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Gene3D G3DSA:2.60.120.430 1326 1486 2.2E-19 T 12-10-2018 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Gene3D G3DSA:2.60.40.1120 508 585 7.8E-15 T 12-10-2018 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Gene3D G3DSA:2.60.40.1120 591 667 2.0E-8 T 12-10-2018 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Gene3D G3DSA:2.60.40.1120 863 949 4.1E-10 T 12-10-2018 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 SUPERFAMILY SSF49785 1339 1488 4.42E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 258 268 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 SUPERFAMILY SSF63825 1087 1257 2.88E-11 T 12-10-2018 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 Gene3D G3DSA:3.40.50.200 172 500 1.1E-67 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 PRINTS PR00723 Subtilisin serine protease family (S8) signature 254 267 4.9E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 PRINTS PR00723 Subtilisin serine protease family (S8) signature 430 446 4.9E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 219 4.9E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_10600 f7a7335193a7a511233853fb1a10b9bd 1489 SUPERFAMILY SSF49464 863 943 4.51E-10 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily TL08_10305 d92ec5f9dcc25b199d72e07467035f5b 646 Gene3D G3DSA:3.40.50.1820 402 645 4.5E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10305 d92ec5f9dcc25b199d72e07467035f5b 646 SUPERFAMILY SSF53474 401 644 5.31E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10305 d92ec5f9dcc25b199d72e07467035f5b 646 Gene3D G3DSA:2.120.10.30 155 358 1.1E-17 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_10305 d92ec5f9dcc25b199d72e07467035f5b 646 Gene3D G3DSA:2.120.10.30 25 154 6.9E-23 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_10305 d92ec5f9dcc25b199d72e07467035f5b 646 Pfam PF00326 Prolyl oligopeptidase family 437 643 6.6E-44 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_10305 d92ec5f9dcc25b199d72e07467035f5b 646 SUPERFAMILY SSF82171 14 276 1.96E-31 T 12-10-2018 TL08_10305 d92ec5f9dcc25b199d72e07467035f5b 646 Pfam PF07676 WD40-like Beta Propeller Repeat 96 123 5.1E-4 T 12-10-2018 IPR011659 WD40-like Beta Propeller TL08_10305 d92ec5f9dcc25b199d72e07467035f5b 646 Pfam PF07676 WD40-like Beta Propeller Repeat 55 76 0.0018 T 12-10-2018 IPR011659 WD40-like Beta Propeller TL08_10305 d92ec5f9dcc25b199d72e07467035f5b 646 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 177 360 1.7E-4 T 12-10-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal TL08_05245 21458797239ad806f6389b2670958ee3 297 SUPERFAMILY SSF53850 78 288 1.41E-27 T 12-10-2018 TL08_05245 21458797239ad806f6389b2670958ee3 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 51 1.4E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_05245 21458797239ad806f6389b2670958ee3 297 Gene3D G3DSA:1.10.10.10 1 79 1.1E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05245 21458797239ad806f6389b2670958ee3 297 Gene3D G3DSA:3.40.190.10 80 278 2.7E-40 T 12-10-2018 TL08_05245 21458797239ad806f6389b2670958ee3 297 Pfam PF03466 LysR substrate binding domain 80 283 9.5E-27 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_05245 21458797239ad806f6389b2670958ee3 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 5.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_05245 21458797239ad806f6389b2670958ee3 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 7 18 5.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_05245 21458797239ad806f6389b2670958ee3 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 28 5.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_05245 21458797239ad806f6389b2670958ee3 297 Gene3D G3DSA:3.40.190.10 151 260 2.7E-40 T 12-10-2018 TL08_05245 21458797239ad806f6389b2670958ee3 297 SUPERFAMILY SSF46785 1 76 3.58E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_18215 62f16083e708f8d2adee802accf9077e 248 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 1.9E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18215 62f16083e708f8d2adee802accf9077e 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.3E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18215 62f16083e708f8d2adee802accf9077e 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.3E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18215 62f16083e708f8d2adee802accf9077e 248 SUPERFAMILY SSF46689 13 82 3.59E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18215 62f16083e708f8d2adee802accf9077e 248 Gene3D G3DSA:1.10.357.10 13 202 2.9E-27 T 12-10-2018 TL08_15140 9298f7bbcf91d6dfb920c654fed0f6b5 643 SMART SM00729 202 418 1.0E-16 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_15140 9298f7bbcf91d6dfb920c654fed0f6b5 643 Gene3D G3DSA:3.80.30.20 201 407 1.2E-15 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TL08_15140 9298f7bbcf91d6dfb920c654fed0f6b5 643 Pfam PF04055 Radical SAM superfamily 207 368 2.8E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_15140 9298f7bbcf91d6dfb920c654fed0f6b5 643 SUPERFAMILY SSF102114 202 407 1.44E-30 T 12-10-2018 TL08_15140 9298f7bbcf91d6dfb920c654fed0f6b5 643 Pfam PF02310 B12 binding domain 66 138 6.9E-10 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TL08_23735 4688e0f40d1d12274e2f531fab300dff 416 Pfam PF04235 Protein of unknown function (DUF418) 294 404 3.4E-8 T 12-10-2018 IPR007349 Domain of unknown function DUF418 TL08_03760 f2cd7e62ab991768b6c5f464dcf1735a 309 SUPERFAMILY SSF53955 140 307 1.69E-37 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_03760 f2cd7e62ab991768b6c5f464dcf1735a 309 Pfam PF13406 Transglycosylase SLT domain 226 271 9.3E-10 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 TL08_03760 f2cd7e62ab991768b6c5f464dcf1735a 309 Gene3D G3DSA:1.10.530.10 151 308 6.2E-6 T 12-10-2018 TL08_12260 b7f5b7f927becab4239d75793b190c79 432 Gene3D G3DSA:3.40.50.2000 254 414 4.4E-41 T 12-10-2018 TL08_12260 b7f5b7f927becab4239d75793b190c79 432 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 225 407 1.1E-10 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 TL08_12260 b7f5b7f927becab4239d75793b190c79 432 Gene3D G3DSA:3.40.50.2000 2 253 2.9E-27 T 12-10-2018 TL08_12260 b7f5b7f927becab4239d75793b190c79 432 SUPERFAMILY SSF53756 3 428 5.56E-63 T 12-10-2018 TL08_01625 179fec5556963367c844faca77e2f4b1 259 Gene3D G3DSA:2.40.10.10 29 259 2.5E-39 T 12-10-2018 TL08_01625 179fec5556963367c844faca77e2f4b1 259 Pfam PF00089 Trypsin 37 254 1.5E-34 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_01625 179fec5556963367c844faca77e2f4b1 259 SMART SM00020 36 254 8.8E-38 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_01625 179fec5556963367c844faca77e2f4b1 259 SUPERFAMILY SSF50494 28 258 1.18E-48 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_01625 179fec5556963367c844faca77e2f4b1 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 65 80 3.6E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_01625 179fec5556963367c844faca77e2f4b1 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 203 215 3.6E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_01625 179fec5556963367c844faca77e2f4b1 259 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 117 131 3.6E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_26190 6aba4b2eb1774b2097bd20f063c859b2 141 Pfam PF11349 Protein of unknown function (DUF3151) 12 135 1.9E-57 T 12-10-2018 IPR014487 Protein of unknown function DUF3151 TL08_26190 6aba4b2eb1774b2097bd20f063c859b2 141 PIRSF PIRSF017349 3 140 9.9E-57 T 12-10-2018 IPR014487 Protein of unknown function DUF3151 TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 SUPERFAMILY SSF53633 4 244 3.53E-71 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 Gene3D G3DSA:3.30.2130.10 250 421 4.6E-65 T 12-10-2018 TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 Pfam PF01842 ACT domain 268 330 1.7E-10 T 12-10-2018 IPR002912 ACT domain TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 Gene3D G3DSA:3.40.1160.10 1 249 1.7E-88 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 SUPERFAMILY SSF55021 334 408 2.14E-22 T 12-10-2018 TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 SUPERFAMILY SSF55021 251 330 1.56E-17 T 12-10-2018 TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 Pfam PF00696 Amino acid kinase family 3 231 1.1E-53 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 Pfam PF13840 ACT domain 341 403 1.2E-15 T 12-10-2018 IPR027795 CASTOR, ACT domain TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 406 4.3E-116 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 PIRSF PIRSF000726 59 414 1.3E-125 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TL08_01135 cc6a5581179b11bcf79f011c65b232ce 421 PIRSF PIRSF000726 1 61 2.8E-21 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 35 477 3.5E-113 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 Gene3D G3DSA:3.40.1190.10 117 334 6.9E-46 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 Gene3D G3DSA:3.40.50.720 29 116 2.0E-12 T 12-10-2018 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 SUPERFAMILY SSF53244 336 477 7.78E-35 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 137 160 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 Pfam PF02875 Mur ligase family, glutamate ligase domain 337 407 7.8E-7 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 SUPERFAMILY SSF53623 133 332 1.96E-42 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 Gene3D G3DSA:3.90.190.20 340 483 2.4E-37 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 Pfam PF08245 Mur ligase middle domain 139 252 1.5E-21 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 SUPERFAMILY SSF51984 30 117 2.62E-14 T 12-10-2018 TL08_09475 03cbec40987dbe570a36c36e9f1d4460 517 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 33 479 31.248 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_14680 21cb08bacc944a9614f5014653d747d1 630 Gene3D G3DSA:3.40.50.300 210 420 2.2E-10 T 12-10-2018 TL08_14680 21cb08bacc944a9614f5014653d747d1 630 SUPERFAMILY SSF52540 230 354 3.88E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14680 21cb08bacc944a9614f5014653d747d1 630 SMART SM00382 262 425 0.0071 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_14680 21cb08bacc944a9614f5014653d747d1 630 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 263 618 1.2E-73 T 12-10-2018 IPR018647 Domain of unknown function DUF2075 TL08_17445 2ba21aacad4148dc1a78fb56ec9d58b4 502 SUPERFAMILY SSF52540 8 239 4.79E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17445 2ba21aacad4148dc1a78fb56ec9d58b4 502 Pfam PF00005 ABC transporter 24 178 2.1E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_17445 2ba21aacad4148dc1a78fb56ec9d58b4 502 Gene3D G3DSA:3.40.50.300 263 494 1.8E-44 T 12-10-2018 TL08_17445 2ba21aacad4148dc1a78fb56ec9d58b4 502 ProSitePatterns PS00211 ABC transporters family signature. 401 415 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_17445 2ba21aacad4148dc1a78fb56ec9d58b4 502 SMART SM00382 287 477 5.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17445 2ba21aacad4148dc1a78fb56ec9d58b4 502 SMART SM00382 33 226 2.6E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17445 2ba21aacad4148dc1a78fb56ec9d58b4 502 SUPERFAMILY SSF52540 273 483 4.86E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17445 2ba21aacad4148dc1a78fb56ec9d58b4 502 Pfam PF00005 ABC transporter 278 428 6.2E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_17445 2ba21aacad4148dc1a78fb56ec9d58b4 502 Gene3D G3DSA:3.40.50.300 5 246 2.1E-54 T 12-10-2018 TL08_26835 726325a816f3860ca7d59505182eb7f3 256 Pfam PF01261 Xylose isomerase-like TIM barrel 16 218 6.2E-21 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_26835 726325a816f3860ca7d59505182eb7f3 256 SMART SM00518 2 254 2.3E-38 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TL08_26835 726325a816f3860ca7d59505182eb7f3 256 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 162 169 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 TL08_26835 726325a816f3860ca7d59505182eb7f3 256 Gene3D G3DSA:3.20.20.150 1 254 3.0E-51 T 12-10-2018 TL08_26835 726325a816f3860ca7d59505182eb7f3 256 SUPERFAMILY SSF51658 1 243 6.15E-48 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 Gene3D G3DSA:1.10.540.10 2 121 3.4E-21 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 SUPERFAMILY SSF47203 227 381 2.74E-53 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 4.6E-46 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 216 3.8E-19 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 SUPERFAMILY SSF56645 2 241 2.88E-61 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 PIRSF PIRSF016578 129 225 0.11 T 12-10-2018 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 PIRSF PIRSF016578 233 380 5.6E-11 T 12-10-2018 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 PIRSF PIRSF016578 58 101 65.0 T 12-10-2018 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 7.6E-17 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 Gene3D G3DSA:1.20.140.10 237 383 2.0E-52 T 12-10-2018 TL08_12595 ae4cf74f5f98210dcd6b54a76fa5cad4 389 Gene3D G3DSA:2.40.110.10 124 236 2.5E-34 T 12-10-2018 TL08_26305 48c86bbb7a1f9f56fa85d48e6cf25e10 357 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 141 229 3.3E-10 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_26305 48c86bbb7a1f9f56fa85d48e6cf25e10 357 SUPERFAMILY SSF50475 135 268 3.73E-14 T 12-10-2018 TL08_26305 48c86bbb7a1f9f56fa85d48e6cf25e10 357 Gene3D G3DSA:2.30.110.10 135 266 9.4E-27 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_07005 c9381d67159805362e5f3887234274ed 300 SUPERFAMILY SSF103481 193 291 5.62E-7 T 12-10-2018 TL08_07005 c9381d67159805362e5f3887234274ed 300 SUPERFAMILY SSF103481 55 148 9.02E-6 T 12-10-2018 TL08_07005 c9381d67159805362e5f3887234274ed 300 Pfam PF00892 EamA-like transporter family 156 283 1.6E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_08080 ba267c428db82ccf304bf45f39544c87 461 Pfam PF07690 Major Facilitator Superfamily 34 389 1.4E-26 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_08080 ba267c428db82ccf304bf45f39544c87 461 Gene3D G3DSA:1.20.1250.20 15 431 1.6E-32 T 12-10-2018 TL08_08080 ba267c428db82ccf304bf45f39544c87 461 SUPERFAMILY SSF103473 16 442 2.49E-42 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_08620 df244cf9d710c069af858ce3fda7e448 298 Pfam PF01522 Polysaccharide deacetylase 77 188 1.5E-7 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TL08_08620 df244cf9d710c069af858ce3fda7e448 298 Gene3D G3DSA:3.20.20.370 21 298 4.0E-58 T 12-10-2018 TL08_08620 df244cf9d710c069af858ce3fda7e448 298 SUPERFAMILY SSF88713 19 297 4.94E-54 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TL08_24335 ce9da039bf84c4cf1307079d9792a60a 277 SUPERFAMILY SSF52540 27 247 5.65E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24335 ce9da039bf84c4cf1307079d9792a60a 277 Gene3D G3DSA:3.40.50.300 20 254 1.2E-58 T 12-10-2018 TL08_24335 ce9da039bf84c4cf1307079d9792a60a 277 SMART SM00382 51 236 4.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_24335 ce9da039bf84c4cf1307079d9792a60a 277 Pfam PF00005 ABC transporter 54 187 1.9E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_24405 ca8ecc729ec55105200de22fb37fcc55 430 Pfam PF02653 Branched-chain amino acid transport system / permease component 65 355 7.5E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_10775 72a373edd46d6f076f5d910b26427e71 149 SUPERFAMILY SSF50475 13 139 1.71E-17 T 12-10-2018 TL08_10775 72a373edd46d6f076f5d910b26427e71 149 Gene3D G3DSA:2.30.110.10 9 143 6.9E-19 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_10775 72a373edd46d6f076f5d910b26427e71 149 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 14 134 2.6E-7 T 12-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 SUPERFAMILY SSF53335 196 561 1.44E-61 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 266 280 5.8E-13 T 12-10-2018 TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 367 391 5.8E-13 T 12-10-2018 TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 242 258 5.8E-13 T 12-10-2018 TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 335 347 5.8E-13 T 12-10-2018 TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 Gene3D G3DSA:3.90.220.20 575 762 6.3E-26 T 12-10-2018 TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 Gene3D G3DSA:3.40.50.150 228 511 1.4E-60 T 12-10-2018 TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 SUPERFAMILY SSF46955 20 81 4.94E-9 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 Pfam PF01420 Type I restriction modification DNA specificity domain 578 743 1.9E-9 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 Pfam PF12728 Helix-turn-helix domain 20 71 1.8E-6 T 12-10-2018 TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 SUPERFAMILY SSF116734 577 761 5.23E-24 T 12-10-2018 TL08_05100 892abaec9e16e8c455a1adb2517ff236 770 Pfam PF02384 N-6 DNA Methylase 246 523 1.0E-53 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TL08_15525 3bc07d5613dd463605b9dd0dc0b3b9ce 767 Gene3D G3DSA:2.130.10.10 459 759 6.1E-122 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_15525 3bc07d5613dd463605b9dd0dc0b3b9ce 767 Gene3D G3DSA:2.130.10.10 51 458 1.8E-179 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_15525 3bc07d5613dd463605b9dd0dc0b3b9ce 767 Pfam PF02012 BNR/Asp-box repeat 362 372 0.11 T 12-10-2018 IPR002860 BNR repeat TL08_15525 3bc07d5613dd463605b9dd0dc0b3b9ce 767 SUPERFAMILY SSF110296 41 447 1.7E-83 T 12-10-2018 TL08_15525 3bc07d5613dd463605b9dd0dc0b3b9ce 767 SUPERFAMILY SSF110296 456 761 9.29E-42 T 12-10-2018 TL08_20400 5417cd126ac8aba694089942dc5606f5 355 Pfam PF13377 Periplasmic binding protein-like domain 186 341 2.2E-28 T 12-10-2018 TL08_20400 5417cd126ac8aba694089942dc5606f5 355 SMART SM00354 9 80 8.6E-23 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_20400 5417cd126ac8aba694089942dc5606f5 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 57 2.1E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_20400 5417cd126ac8aba694089942dc5606f5 355 Gene3D G3DSA:1.10.260.40 9 68 1.1E-17 T 12-10-2018 TL08_20400 5417cd126ac8aba694089942dc5606f5 355 SUPERFAMILY SSF53822 70 343 1.81E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_20400 5417cd126ac8aba694089942dc5606f5 355 SUPERFAMILY SSF47413 9 69 5.16E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_20400 5417cd126ac8aba694089942dc5606f5 355 Gene3D G3DSA:3.40.50.2300 175 304 4.8E-66 T 12-10-2018 TL08_20400 5417cd126ac8aba694089942dc5606f5 355 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 12-10-2018 TL08_20400 5417cd126ac8aba694089942dc5606f5 355 Gene3D G3DSA:3.40.50.2300 71 319 4.8E-66 T 12-10-2018 TL08_12740 4b47b12017ac488b8988f2964e745229 521 SUPERFAMILY SSF52540 276 507 9.19E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12740 4b47b12017ac488b8988f2964e745229 521 Gene3D G3DSA:3.40.50.300 273 513 2.9E-41 T 12-10-2018 TL08_12740 4b47b12017ac488b8988f2964e745229 521 ProSitePatterns PS00211 ABC transporters family signature. 422 436 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12740 4b47b12017ac488b8988f2964e745229 521 Pfam PF00005 ABC transporter 41 189 9.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12740 4b47b12017ac488b8988f2964e745229 521 SUPERFAMILY SSF52540 26 247 1.27E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12740 4b47b12017ac488b8988f2964e745229 521 Pfam PF00005 ABC transporter 294 449 1.1E-14 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12740 4b47b12017ac488b8988f2964e745229 521 Gene3D G3DSA:3.40.50.300 24 260 2.2E-56 T 12-10-2018 TL08_12740 4b47b12017ac488b8988f2964e745229 521 SMART SM00382 49 236 1.6E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 160 253 2.0E-12 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 PRINTS PR00502 NUDIX hydrolase family signature 48 62 6.7E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 PRINTS PR00502 NUDIX hydrolase family signature 62 77 6.7E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 SMART SM00855 159 273 1.5E-9 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 Pfam PF00293 NUDIX domain 32 149 6.9E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 Gene3D G3DSA:3.40.50.1240 159 320 4.5E-34 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 SUPERFAMILY SSF55811 12 152 1.34E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 SUPERFAMILY SSF53254 157 312 5.3E-20 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_22635 2108c24bbf087ebe849b1e055c07bfa2 323 Gene3D G3DSA:3.90.79.10 16 158 3.3E-39 T 12-10-2018 TL08_19165 9923f710fdde5223dc98134b33e6e1e0 298 Gene3D G3DSA:3.40.190.290 91 295 2.3E-48 T 12-10-2018 TL08_19165 9923f710fdde5223dc98134b33e6e1e0 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.1E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19165 9923f710fdde5223dc98134b33e6e1e0 298 Gene3D G3DSA:1.10.10.10 1 90 4.2E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19165 9923f710fdde5223dc98134b33e6e1e0 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19165 9923f710fdde5223dc98134b33e6e1e0 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19165 9923f710fdde5223dc98134b33e6e1e0 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19165 9923f710fdde5223dc98134b33e6e1e0 298 SUPERFAMILY SSF53850 88 293 1.33E-46 T 12-10-2018 TL08_19165 9923f710fdde5223dc98134b33e6e1e0 298 Pfam PF03466 LysR substrate binding domain 88 291 2.4E-46 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_19165 9923f710fdde5223dc98134b33e6e1e0 298 SUPERFAMILY SSF46785 2 110 9.98E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_08650 b4408aacd993a3daf20a0d567029bc54 352 Pfam PF13830 Domain of unknown function (DUF4192) 14 327 9.6E-80 T 12-10-2018 IPR025447 Protein of unknown function DUF4192 TL08_26640 ad6e7c7d0aaaf44aa4e86d673daca215 614 SUPERFAMILY SSF56645 35 281 1.09E-41 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_26640 ad6e7c7d0aaaf44aa4e86d673daca215 614 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 477 610 3.0E-29 T 12-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain TL08_26640 ad6e7c7d0aaaf44aa4e86d673daca215 614 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 275 4.1E-17 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TL08_26640 ad6e7c7d0aaaf44aa4e86d673daca215 614 Gene3D G3DSA:1.20.140.10 296 466 1.4E-31 T 12-10-2018 TL08_26640 ad6e7c7d0aaaf44aa4e86d673daca215 614 Gene3D G3DSA:2.40.110.10 160 295 8.1E-24 T 12-10-2018 TL08_26640 ad6e7c7d0aaaf44aa4e86d673daca215 614 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 1.8E-8 T 12-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria TL08_26640 ad6e7c7d0aaaf44aa4e86d673daca215 614 Gene3D G3DSA:1.10.540.10 35 155 7.5E-7 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_26640 ad6e7c7d0aaaf44aa4e86d673daca215 614 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 291 457 2.1E-13 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TL08_26640 ad6e7c7d0aaaf44aa4e86d673daca215 614 SUPERFAMILY SSF47203 295 484 2.09E-31 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_16335 bd2d6e202298dda7421bb0a0fcbdd1d8 256 SMART SM00382 48 234 9.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_16335 bd2d6e202298dda7421bb0a0fcbdd1d8 256 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_16335 bd2d6e202298dda7421bb0a0fcbdd1d8 256 Gene3D G3DSA:3.40.50.300 18 255 7.7E-67 T 12-10-2018 TL08_16335 bd2d6e202298dda7421bb0a0fcbdd1d8 256 Pfam PF00005 ABC transporter 39 185 4.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_16335 bd2d6e202298dda7421bb0a0fcbdd1d8 256 SUPERFAMILY SSF52540 20 240 1.86E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_15730 0490ec20be919dfe6e2b3a3120d2c606 742 Pfam PF13569 Domain of unknown function (DUF4132) 467 651 1.6E-52 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_22820 7101834a762fde6b8afbe9a68fcf546e 460 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 391 1.8E-27 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_22820 7101834a762fde6b8afbe9a68fcf546e 460 SUPERFAMILY SSF52540 2 398 5.08E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01955 d9a4157b7957d0b4cad37aa08170efd2 349 SUPERFAMILY SSF53822 58 347 1.73E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_01955 d9a4157b7957d0b4cad37aa08170efd2 349 SMART SM00354 1 68 8.0E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_01955 d9a4157b7957d0b4cad37aa08170efd2 349 Gene3D G3DSA:1.10.260.40 2 45 1.7E-15 T 12-10-2018 TL08_01955 d9a4157b7957d0b4cad37aa08170efd2 349 Gene3D G3DSA:3.40.50.2300 173 301 1.1E-69 T 12-10-2018 TL08_01955 d9a4157b7957d0b4cad37aa08170efd2 349 Gene3D G3DSA:3.40.50.2300 56 317 1.1E-69 T 12-10-2018 TL08_01955 d9a4157b7957d0b4cad37aa08170efd2 349 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 TL08_01955 d9a4157b7957d0b4cad37aa08170efd2 349 Pfam PF13377 Periplasmic binding protein-like domain 181 344 5.6E-37 T 12-10-2018 TL08_01955 d9a4157b7957d0b4cad37aa08170efd2 349 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 46 5.1E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_01955 d9a4157b7957d0b4cad37aa08170efd2 349 SUPERFAMILY SSF47413 3 47 4.31E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_15210 7289968234e0ba4c01f6309e698c9b2e 398 Pfam PF07730 Histidine kinase 182 246 1.1E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_15210 7289968234e0ba4c01f6309e698c9b2e 398 Gene3D G3DSA:3.30.565.10 258 396 4.0E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_15210 7289968234e0ba4c01f6309e698c9b2e 398 SUPERFAMILY SSF55874 276 375 5.77E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_14485 720828f260569f6997b613d0324112c3 572 Pfam PF00664 ABC transporter transmembrane region 58 278 2.6E-16 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_14485 720828f260569f6997b613d0324112c3 572 SMART SM00382 357 541 5.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_14485 720828f260569f6997b613d0324112c3 572 ProSitePatterns PS00211 ABC transporters family signature. 467 481 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_14485 720828f260569f6997b613d0324112c3 572 Pfam PF00005 ABC transporter 348 495 4.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_14485 720828f260569f6997b613d0324112c3 572 Gene3D G3DSA:1.20.1560.10 1 318 3.1E-39 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_14485 720828f260569f6997b613d0324112c3 572 SUPERFAMILY SSF52540 326 565 5.72E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14485 720828f260569f6997b613d0324112c3 572 Gene3D G3DSA:3.40.50.300 324 572 8.4E-77 T 12-10-2018 TL08_14485 720828f260569f6997b613d0324112c3 572 SUPERFAMILY SSF90123 6 317 1.83E-45 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_19150 1a92b091b7889de78f52431d991f97cb 232 Gene3D G3DSA:3.40.30.10 15 202 1.9E-20 T 12-10-2018 TL08_19150 1a92b091b7889de78f52431d991f97cb 232 SUPERFAMILY SSF52833 15 193 6.27E-15 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_19150 1a92b091b7889de78f52431d991f97cb 232 Pfam PF01323 DSBA-like thioredoxin domain 15 177 3.4E-9 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 TL08_01810 52d05c39fa2b2fcbe070b0b92a0ef77b 412 Gene3D G3DSA:2.40.110.10 138 239 5.9E-32 T 12-10-2018 TL08_01810 52d05c39fa2b2fcbe070b0b92a0ef77b 412 SUPERFAMILY SSF56645 66 240 1.44E-24 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_01810 52d05c39fa2b2fcbe070b0b92a0ef77b 412 SUPERFAMILY SSF47203 240 388 1.51E-11 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_01810 52d05c39fa2b2fcbe070b0b92a0ef77b 412 Gene3D G3DSA:1.20.140.10 240 368 5.9E-32 T 12-10-2018 TL08_01810 52d05c39fa2b2fcbe070b0b92a0ef77b 412 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 230 1.3E-12 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TL08_01810 52d05c39fa2b2fcbe070b0b92a0ef77b 412 Gene3D G3DSA:1.10.540.10 110 137 5.9E-32 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_01810 52d05c39fa2b2fcbe070b0b92a0ef77b 412 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 376 1.7E-9 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TL08_05920 6dbc3b6af998127d6ead4191c2b68e00 160 Gene3D G3DSA:1.20.1290.10 17 155 4.1E-44 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TL08_05920 6dbc3b6af998127d6ead4191c2b68e00 160 SUPERFAMILY SSF69118 19 151 1.03E-39 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TL08_05920 6dbc3b6af998127d6ead4191c2b68e00 160 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 107 4.4E-16 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TL08_05920 6dbc3b6af998127d6ead4191c2b68e00 160 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 91 5.5E-12 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TL08_05345 48747894b6fc946487656a26c6351676 318 Pfam PF13280 WYL domain 133 308 2.6E-23 T 12-10-2018 IPR026881 WYL domain TL08_05345 48747894b6fc946487656a26c6351676 318 Gene3D G3DSA:1.10.10.10 1 58 8.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05345 48747894b6fc946487656a26c6351676 318 Pfam PF08279 HTH domain 2 55 1.0E-12 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TL08_05345 48747894b6fc946487656a26c6351676 318 SUPERFAMILY SSF46785 2 55 4.54E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05345 48747894b6fc946487656a26c6351676 318 PIRSF PIRSF016838 57 318 1.1E-19 T 12-10-2018 IPR028349 Protein PafC TL08_05345 48747894b6fc946487656a26c6351676 318 PIRSF PIRSF016838 1 42 160.0 T 12-10-2018 IPR028349 Protein PafC TL08_07265 550183e946eee364cec14034384dad0c 75 ProSitePatterns PS01143 Ribosomal protein L31 signature. 41 62 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_07265 550183e946eee364cec14034384dad0c 75 PRINTS PR01249 Ribosomal protein L31 signature 7 24 3.2E-21 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_07265 550183e946eee364cec14034384dad0c 75 PRINTS PR01249 Ribosomal protein L31 signature 37 52 3.2E-21 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_07265 550183e946eee364cec14034384dad0c 75 PRINTS PR01249 Ribosomal protein L31 signature 52 70 3.2E-21 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_07265 550183e946eee364cec14034384dad0c 75 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 6 74 26.957 T 12-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_07265 550183e946eee364cec14034384dad0c 75 Pfam PF01197 Ribosomal protein L31 7 71 2.7E-29 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_07265 550183e946eee364cec14034384dad0c 75 SUPERFAMILY SSF143800 7 71 7.06E-24 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_07265 550183e946eee364cec14034384dad0c 75 TIGRFAM TIGR00105 L31: ribosomal protein bL31 7 72 7.7E-31 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_07265 550183e946eee364cec14034384dad0c 75 Gene3D G3DSA:2.30.170.50 6 75 2.1E-29 T 12-10-2018 TL08_00315 d62c05ec75e44adf92572ce551db99c0 1245 Pfam PF05050 Methyltransferase FkbM domain 1045 1209 5.0E-12 T 12-10-2018 IPR006342 Methyltransferase FkbM TL08_00315 d62c05ec75e44adf92572ce551db99c0 1245 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 1042 1184 1.6E-19 T 12-10-2018 IPR006342 Methyltransferase FkbM TL08_00315 d62c05ec75e44adf92572ce551db99c0 1245 SUPERFAMILY SSF53335 1015 1210 1.82E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_00315 d62c05ec75e44adf92572ce551db99c0 1245 SUPERFAMILY SSF53756 495 779 3.4E-30 T 12-10-2018 TL08_00315 d62c05ec75e44adf92572ce551db99c0 1245 Pfam PF00534 Glycosyl transferases group 1 584 757 8.2E-12 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_00315 d62c05ec75e44adf92572ce551db99c0 1245 SUPERFAMILY SSF53448 7 257 2.19E-13 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00315 d62c05ec75e44adf92572ce551db99c0 1245 Gene3D G3DSA:3.40.50.2000 572 781 1.3E-33 T 12-10-2018 TL08_00315 d62c05ec75e44adf92572ce551db99c0 1245 Gene3D G3DSA:3.40.50.150 1030 1210 3.6E-28 T 12-10-2018 TL08_03845 6457f0eefafe1d473c2bd4b5a863d681 269 Pfam PF04203 Sortase family 168 266 3.3E-9 T 12-10-2018 IPR005754 Sortase family TL08_03845 6457f0eefafe1d473c2bd4b5a863d681 269 Gene3D G3DSA:2.40.260.10 123 268 9.4E-14 T 12-10-2018 IPR023365 Sortase domain superfamily TL08_03845 6457f0eefafe1d473c2bd4b5a863d681 269 SUPERFAMILY SSF63817 123 264 1.45E-10 T 12-10-2018 IPR023365 Sortase domain superfamily TL08_06615 a23ee0c4e5bb324ac8ff4a2df3305646 340 SUPERFAMILY SSF53335 52 291 3.47E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_06615 a23ee0c4e5bb324ac8ff4a2df3305646 340 Pfam PF08241 Methyltransferase domain 91 188 9.3E-25 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_06615 a23ee0c4e5bb324ac8ff4a2df3305646 340 Gene3D G3DSA:3.40.50.150 23 300 1.2E-36 T 12-10-2018 TL08_20105 d9d693ca31f137d50c95c59bb3e4636d 281 Pfam PF13424 Tetratricopeptide repeat 121 194 2.3E-13 T 12-10-2018 TL08_20105 d9d693ca31f137d50c95c59bb3e4636d 281 SUPERFAMILY SSF48452 116 242 1.61E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20105 d9d693ca31f137d50c95c59bb3e4636d 281 Gene3D G3DSA:1.25.40.10 52 192 1.3E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20105 d9d693ca31f137d50c95c59bb3e4636d 281 Gene3D G3DSA:1.25.40.10 193 261 7.8E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20105 d9d693ca31f137d50c95c59bb3e4636d 281 Pfam PF13374 Tetratricopeptide repeat 79 120 7.3E-6 T 12-10-2018 TL08_20105 d9d693ca31f137d50c95c59bb3e4636d 281 Pfam PF13374 Tetratricopeptide repeat 205 245 0.0059 T 12-10-2018 TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 Hamap MF_01974 Methionine aminopeptidase [map]. 8 261 37.902 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 172 184 2.0E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 203 215 2.0E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 2.0E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 96 112 2.0E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 SUPERFAMILY SSF55920 9 259 4.06E-76 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 8 260 5.9E-83 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 Pfam PF00557 Metallopeptidase family M24 17 252 9.2E-44 T 12-10-2018 IPR000994 Peptidase M24 TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 Gene3D G3DSA:3.90.230.10 1 263 6.5E-90 T 12-10-2018 TL08_03100 d610a9a888cb44e7c9f91466f009759f 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 178 196 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_05935 0031594924e055a5cddf7a321dbe8fa0 483 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 426 4.4E-73 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TL08_05935 0031594924e055a5cddf7a321dbe8fa0 483 SUPERFAMILY SSF103473 6 470 8.37E-60 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_05935 0031594924e055a5cddf7a321dbe8fa0 483 Pfam PF07690 Major Facilitator Superfamily 20 413 5.8E-39 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_05935 0031594924e055a5cddf7a321dbe8fa0 483 Gene3D G3DSA:1.20.1250.20 262 471 3.6E-18 T 12-10-2018 TL08_05935 0031594924e055a5cddf7a321dbe8fa0 483 Gene3D G3DSA:1.20.1720.10 16 259 1.4E-38 T 12-10-2018 TL08_26775 cc170b37bca921e4ebe12ece5a313749 238 SUPERFAMILY SSF46785 8 65 2.4E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_26775 cc170b37bca921e4ebe12ece5a313749 238 Gene3D G3DSA:1.10.10.10 7 68 4.8E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26775 cc170b37bca921e4ebe12ece5a313749 238 Pfam PF13280 WYL domain 143 235 1.5E-19 T 12-10-2018 IPR026881 WYL domain TL08_26775 cc170b37bca921e4ebe12ece5a313749 238 Pfam PF08279 HTH domain 10 65 5.2E-13 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TL08_21515 9b1caffd96fbb55073a4cc05c8522c3e 1642 SMART SM00382 48 240 0.0035 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_21515 9b1caffd96fbb55073a4cc05c8522c3e 1642 Gene3D G3DSA:3.40.50.300 20 234 2.2E-55 T 12-10-2018 TL08_21515 9b1caffd96fbb55073a4cc05c8522c3e 1642 SMART SM00487 31 246 2.4E-31 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_21515 9b1caffd96fbb55073a4cc05c8522c3e 1642 Pfam PF00270 DEAD/DEAH box helicase 36 219 3.4E-23 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_21515 9b1caffd96fbb55073a4cc05c8522c3e 1642 SUPERFAMILY SSF52540 45 486 2.18E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21515 9b1caffd96fbb55073a4cc05c8522c3e 1642 Pfam PF00271 Helicase conserved C-terminal domain 416 481 3.1E-11 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_21515 9b1caffd96fbb55073a4cc05c8522c3e 1642 Pfam PF08494 DEAD/H associated 744 937 5.8E-71 T 12-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TL08_21515 9b1caffd96fbb55073a4cc05c8522c3e 1642 SMART SM00490 324 481 2.3E-12 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_00915 0429d91ebd0d1623116a50e5b1b2bcce 268 Gene3D G3DSA:3.40.50.300 1 268 3.3E-79 T 12-10-2018 TL08_00915 0429d91ebd0d1623116a50e5b1b2bcce 268 SMART SM00382 33 232 1.7E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_00915 0429d91ebd0d1623116a50e5b1b2bcce 268 Pfam PF00005 ABC transporter 25 183 3.3E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_00915 0429d91ebd0d1623116a50e5b1b2bcce 268 SUPERFAMILY SSF52540 4 254 1.43E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06995 22a0fbb5c4da9a43a70a8793ade26ea6 179 Gene3D G3DSA:3.40.630.30 5 165 1.3E-22 T 12-10-2018 TL08_06995 22a0fbb5c4da9a43a70a8793ade26ea6 179 Pfam PF00583 Acetyltransferase (GNAT) family 54 156 7.3E-6 T 12-10-2018 IPR000182 GNAT domain TL08_06995 22a0fbb5c4da9a43a70a8793ade26ea6 179 SUPERFAMILY SSF55729 10 168 1.21E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_00535 5dddc933025a7d3c82e0b328498b6611 255 Gene3D G3DSA:3.20.180.10 160 248 1.2E-12 T 12-10-2018 IPR037119 Haem oxygenase HugZ-like superfamily TL08_00535 5dddc933025a7d3c82e0b328498b6611 255 SUPERFAMILY SSF50475 59 251 1.1E-18 T 12-10-2018 TL08_00535 5dddc933025a7d3c82e0b328498b6611 255 Pfam PF10615 Protein of unknown function (DUF2470) 171 242 3.7E-5 T 12-10-2018 IPR019595 Domain of unknown function DUF2470 TL08_10485 9fda3b67706c9e99771986a1797371f0 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 250 1.9E-63 T 12-10-2018 TL08_10485 9fda3b67706c9e99771986a1797371f0 250 SUPERFAMILY SSF51735 7 249 3.1E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_10485 9fda3b67706c9e99771986a1797371f0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10485 9fda3b67706c9e99771986a1797371f0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10485 9fda3b67706c9e99771986a1797371f0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10485 9fda3b67706c9e99771986a1797371f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 8.8E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10485 9fda3b67706c9e99771986a1797371f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.8E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10485 9fda3b67706c9e99771986a1797371f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 8.8E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10485 9fda3b67706c9e99771986a1797371f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.8E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10485 9fda3b67706c9e99771986a1797371f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.8E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10485 9fda3b67706c9e99771986a1797371f0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 8.8E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10485 9fda3b67706c9e99771986a1797371f0 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 191 0.0072 T 12-10-2018 TL08_10485 9fda3b67706c9e99771986a1797371f0 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_10485 9fda3b67706c9e99771986a1797371f0 250 Gene3D G3DSA:3.40.50.720 3 250 1.9E-77 T 12-10-2018 TL08_18790 857c027fcf5e1ab2393dac5e86fafd1c 190 Pfam PF13527 Acetyltransferase (GNAT) domain 24 146 2.5E-10 T 12-10-2018 TL08_18790 857c027fcf5e1ab2393dac5e86fafd1c 190 Gene3D G3DSA:3.40.630.30 19 183 1.6E-29 T 12-10-2018 TL08_18790 857c027fcf5e1ab2393dac5e86fafd1c 190 SUPERFAMILY SSF55729 24 149 2.62E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_00890 1d28d4950b7ba50f8c2f074d57880b5b 297 Pfam PF00455 DeoR C terminal sensor domain 76 233 1.3E-39 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain TL08_00890 1d28d4950b7ba50f8c2f074d57880b5b 297 SUPERFAMILY SSF100950 75 233 4.19E-24 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_00890 1d28d4950b7ba50f8c2f074d57880b5b 297 SMART SM00420 8 59 9.8E-14 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_00890 1d28d4950b7ba50f8c2f074d57880b5b 297 SUPERFAMILY SSF46785 13 60 1.21E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_00890 1d28d4950b7ba50f8c2f074d57880b5b 297 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 2.7E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_00890 1d28d4950b7ba50f8c2f074d57880b5b 297 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 2.7E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_00890 1d28d4950b7ba50f8c2f074d57880b5b 297 Pfam PF08220 DeoR-like helix-turn-helix domain 8 58 8.2E-14 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_00890 1d28d4950b7ba50f8c2f074d57880b5b 297 Gene3D G3DSA:1.10.10.10 5 87 3.1E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_00890 1d28d4950b7ba50f8c2f074d57880b5b 297 SMART SM01134 73 234 2.4E-54 T 12-10-2018 TL08_21455 f48779d4d504d245ae4878df666fb4cc 246 Gene3D G3DSA:3.40.50.1400 124 244 8.9E-20 T 12-10-2018 TL08_21455 f48779d4d504d245ae4878df666fb4cc 246 Gene3D G3DSA:3.40.50.1400 1 121 6.1E-25 T 12-10-2018 TL08_21455 f48779d4d504d245ae4878df666fb4cc 246 Pfam PF01903 CbiX 133 229 1.6E-14 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 TL08_21455 f48779d4d504d245ae4878df666fb4cc 246 Pfam PF01903 CbiX 10 109 5.5E-17 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 TL08_21455 f48779d4d504d245ae4878df666fb4cc 246 SUPERFAMILY SSF53800 5 236 2.29E-31 T 12-10-2018 TL08_19300 7d09652a3f0d77e62bbfd6bb9c7dbd8e 152 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 132 8.5E-34 T 12-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 TL08_19300 7d09652a3f0d77e62bbfd6bb9c7dbd8e 152 Gene3D G3DSA:3.40.930.10 4 147 2.4E-35 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TL08_19300 7d09652a3f0d77e62bbfd6bb9c7dbd8e 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 145 6.7E-32 T 12-10-2018 IPR002178 PTS EIIA type-2 domain TL08_19300 7d09652a3f0d77e62bbfd6bb9c7dbd8e 152 SUPERFAMILY SSF55804 4 146 3.27E-33 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 Gene3D G3DSA:1.10.274.10 25 144 4.2E-50 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 Pfam PF05524 PEP-utilising enzyme, N-terminal 7 124 1.8E-20 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 280 299 1.2E-19 T 12-10-2018 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 442 457 1.2E-19 T 12-10-2018 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 478 490 1.2E-19 T 12-10-2018 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 425 440 1.2E-19 T 12-10-2018 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 SUPERFAMILY SSF52009 123 237 4.58E-26 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 SUPERFAMILY SSF51621 245 527 1.23E-80 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 517 4.3E-72 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 PIRSF PIRSF000732 2 548 2.4E-141 T 12-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 222 1.1E-19 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 Gene3D G3DSA:3.20.20.60 230 547 4.5E-89 T 12-10-2018 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 Gene3D G3DSA:3.50.30.10 8 227 4.2E-50 T 12-10-2018 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 425 443 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 SUPERFAMILY SSF47831 32 141 9.15E-20 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 TL08_26955 f50dbfe4b9091c19f4828d8a700665f6 548 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 182 193 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TL08_23920 475b64d68cc4afcef67a37a2dc2ce776 317 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 312 1.4E-115 T 12-10-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV-5884 family TL08_23920 475b64d68cc4afcef67a37a2dc2ce776 317 SUPERFAMILY SSF56059 132 312 3.54E-14 T 12-10-2018 TL08_23920 475b64d68cc4afcef67a37a2dc2ce776 317 Gene3D G3DSA:3.30.470.20 206 314 2.0E-17 T 12-10-2018 TL08_01985 250a19edef828bffd70caf2e6be036c7 327 Gene3D G3DSA:3.20.20.100 15 327 1.3E-109 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_01985 250a19edef828bffd70caf2e6be036c7 327 SUPERFAMILY SSF51430 13 325 3.14E-87 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_01985 250a19edef828bffd70caf2e6be036c7 327 Pfam PF00248 Aldo/keto reductase family 28 326 1.2E-65 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_19110 2c788be34aa28adeb60719638a043285 402 Gene3D G3DSA:3.40.640.10 47 289 6.0E-124 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_19110 2c788be34aa28adeb60719638a043285 402 Gene3D G3DSA:3.90.1150.10 39 391 6.0E-124 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_19110 2c788be34aa28adeb60719638a043285 402 SUPERFAMILY SSF53383 75 400 9.71E-33 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_22790 7b344c288818d24a364b6757966f8e05 304 SUPERFAMILY SSF52283 34 116 6.38E-5 T 12-10-2018 TL08_22790 7b344c288818d24a364b6757966f8e05 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 269 1.3E-43 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TL08_22790 7b344c288818d24a364b6757966f8e05 304 Gene3D G3DSA:3.40.50.720 17 300 4.3E-72 T 12-10-2018 TL08_22790 7b344c288818d24a364b6757966f8e05 304 SUPERFAMILY SSF51735 96 270 1.66E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_22790 7b344c288818d24a364b6757966f8e05 304 Gene3D G3DSA:3.40.50.720 94 276 4.3E-72 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 Gene3D G3DSA:1.10.246.130 269 383 1.0E-21 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 487 504 9.0E-28 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 9.0E-28 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 42 67 9.0E-28 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 9.0E-28 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 409 427 9.0E-28 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 463 478 9.0E-28 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 Pfam PF01019 Gamma-glutamyltranspeptidase 35 591 2.8E-128 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 Gene3D G3DSA:3.60.20.40 409 598 3.1E-45 T 12-10-2018 TL08_17055 4d9b6052e3972eb68cd7b802b99872f4 599 SUPERFAMILY SSF56235 10 598 4.3E-127 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_05140 0fba257bbf2a6ca3bbafb62f1ffd220f 652 SUPERFAMILY SSF51004 60 310 7.32E-17 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily TL08_05140 0fba257bbf2a6ca3bbafb62f1ffd220f 652 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 618 650 5.3E-4 T 12-10-2018 TL08_23230 dcfa6a2101fa0b1390bb51a8cbca0ba1 591 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 60 590 1.2E-237 T 12-10-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 TL08_23230 dcfa6a2101fa0b1390bb51a8cbca0ba1 591 Pfam PF00171 Aldehyde dehydrogenase family 105 570 3.6E-100 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_23230 dcfa6a2101fa0b1390bb51a8cbca0ba1 591 Gene3D G3DSA:3.40.605.10 63 576 5.1E-196 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_23230 dcfa6a2101fa0b1390bb51a8cbca0ba1 591 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 341 348 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TL08_23230 dcfa6a2101fa0b1390bb51a8cbca0ba1 591 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 369 380 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TL08_23230 dcfa6a2101fa0b1390bb51a8cbca0ba1 591 Gene3D G3DSA:3.40.309.10 346 544 5.1E-196 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_23230 dcfa6a2101fa0b1390bb51a8cbca0ba1 591 SUPERFAMILY SSF53720 57 576 4.32E-121 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_06840 36d32f8aee9c180586973c6a7121d2fb 183 SUPERFAMILY SSF55729 4 169 4.69E-42 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_06840 36d32f8aee9c180586973c6a7121d2fb 183 Gene3D G3DSA:3.40.630.30 3 179 2.5E-45 T 12-10-2018 TL08_06840 36d32f8aee9c180586973c6a7121d2fb 183 Pfam PF13302 Acetyltransferase (GNAT) domain 7 144 2.0E-22 T 12-10-2018 IPR000182 GNAT domain TL08_08990 b2d8e3e2b0a4885a7dea72f4adc44214 192 Pfam PF05685 Putative restriction endonuclease 24 167 4.2E-17 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TL08_08990 b2d8e3e2b0a4885a7dea72f4adc44214 192 Gene3D G3DSA:3.90.1570.10 4 146 2.4E-19 T 12-10-2018 TL08_08990 b2d8e3e2b0a4885a7dea72f4adc44214 192 SUPERFAMILY SSF52980 6 143 1.55E-18 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TL08_15010 94ddfb04dffe431c5935bb3798661d5e 267 SUPERFAMILY SSF47413 5 64 1.32E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_15010 94ddfb04dffe431c5935bb3798661d5e 267 Gene3D G3DSA:1.10.260.40 4 67 4.1E-12 T 12-10-2018 TL08_15010 94ddfb04dffe431c5935bb3798661d5e 267 Pfam PF13560 Helix-turn-helix domain 7 66 9.6E-11 T 12-10-2018 TL08_15010 94ddfb04dffe431c5935bb3798661d5e 267 SMART SM00530 10 65 1.1E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_05895 1550bad7ac03f1c3af3dcd972ec07671 400 Pfam PF01761 3-dehydroquinate synthase 83 342 3.3E-59 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TL08_05895 1550bad7ac03f1c3af3dcd972ec07671 400 Gene3D G3DSA:1.20.1090.10 186 385 1.4E-42 T 12-10-2018 TL08_05895 1550bad7ac03f1c3af3dcd972ec07671 400 SUPERFAMILY SSF56796 19 368 1.57E-74 T 12-10-2018 TL08_05895 1550bad7ac03f1c3af3dcd972ec07671 400 Gene3D G3DSA:3.40.50.1970 15 184 1.8E-41 T 12-10-2018 TL08_05895 1550bad7ac03f1c3af3dcd972ec07671 400 PIRSF PIRSF001455 18 383 2.1E-80 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TL08_11820 cfdf7626ebb1a70f6fe72bff590500d9 256 Pfam PF00005 ABC transporter 23 174 6.3E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_11820 cfdf7626ebb1a70f6fe72bff590500d9 256 SUPERFAMILY SSF52540 4 233 7.46E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11820 cfdf7626ebb1a70f6fe72bff590500d9 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 4.4E-103 T 12-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TL08_11820 cfdf7626ebb1a70f6fe72bff590500d9 256 Gene3D G3DSA:3.40.50.300 1 245 6.8E-52 T 12-10-2018 TL08_11820 cfdf7626ebb1a70f6fe72bff590500d9 256 SMART SM00382 32 225 4.6E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_18550 5ac86cce894b3c687101fd5b463831fc 275 Gene3D G3DSA:3.60.15.10 42 268 1.0E-9 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_18550 5ac86cce894b3c687101fd5b463831fc 275 Pfam PF00753 Metallo-beta-lactamase superfamily 78 200 2.5E-5 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_18550 5ac86cce894b3c687101fd5b463831fc 275 SUPERFAMILY SSF56281 57 243 4.22E-24 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_15600 077404f2db6fd51f0ad8d7df4b157992 405 Pfam PF00196 Bacterial regulatory proteins, luxR family 337 389 4.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15600 077404f2db6fd51f0ad8d7df4b157992 405 SMART SM00421 334 391 1.9E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15600 077404f2db6fd51f0ad8d7df4b157992 405 ProSitePatterns PS00622 LuxR-type HTH domain signature. 351 378 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15600 077404f2db6fd51f0ad8d7df4b157992 405 Gene3D G3DSA:1.10.10.10 240 402 1.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_15600 077404f2db6fd51f0ad8d7df4b157992 405 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 367 379 2.5E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15600 077404f2db6fd51f0ad8d7df4b157992 405 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 337 351 2.5E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15600 077404f2db6fd51f0ad8d7df4b157992 405 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 351 367 2.5E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_15600 077404f2db6fd51f0ad8d7df4b157992 405 SUPERFAMILY SSF46894 324 390 7.48E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_23035 1a557c0df501a6fb3e1ab33327d95274 385 Pfam PF00144 Beta-lactamase 24 359 1.1E-46 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_23035 1a557c0df501a6fb3e1ab33327d95274 385 Gene3D G3DSA:3.40.710.10 16 367 1.4E-59 T 12-10-2018 TL08_23035 1a557c0df501a6fb3e1ab33327d95274 385 SUPERFAMILY SSF56601 18 360 3.06E-56 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 Pfam PF04542 Sigma-70 region 2 15 78 7.2E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 SUPERFAMILY SSF88659 89 167 3.92E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 SUPERFAMILY SSF54427 180 294 3.04E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 Gene3D G3DSA:1.10.10.10 104 169 4.9E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 Gene3D G3DSA:3.10.450.50 174 294 4.5E-6 T 12-10-2018 TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 Gene3D G3DSA:1.10.1740.10 7 82 2.8E-10 T 12-10-2018 TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 SUPERFAMILY SSF88946 15 93 1.92E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 Pfam PF08281 Sigma-70, region 4 114 165 1.8E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 167 3.6E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_09700 b38c1d3c9291bd2fe4b6398f2169a426 297 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 14 292 1.0E-107 T 12-10-2018 IPR014303 RNA polymerase sigma-70, ECF type TL08_07775 1a4f83b5256dcc94aa51be0fb323c824 323 SUPERFAMILY SSF51182 40 302 1.58E-64 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_07775 1a4f83b5256dcc94aa51be0fb323c824 323 Gene3D G3DSA:2.60.120.10 28 266 1.1E-62 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_07775 1a4f83b5256dcc94aa51be0fb323c824 323 Pfam PF02678 Pirin 43 140 1.5E-28 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 TL08_07775 1a4f83b5256dcc94aa51be0fb323c824 323 PIRSF PIRSF006232 21 302 5.5E-74 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 TL08_07775 1a4f83b5256dcc94aa51be0fb323c824 323 Pfam PF05726 Pirin C-terminal cupin domain 192 289 6.8E-14 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 TL08_07385 08bb1cdb9fb5f42862971ac75b9935ae 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 208 1.0E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_07385 08bb1cdb9fb5f42862971ac75b9935ae 231 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 8 209 1.6E-72 T 12-10-2018 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC TL08_07385 08bb1cdb9fb5f42862971ac75b9935ae 231 Gene3D G3DSA:1.10.3720.10 3 211 8.1E-47 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07385 08bb1cdb9fb5f42862971ac75b9935ae 231 SUPERFAMILY SSF161098 6 194 1.03E-39 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07385 08bb1cdb9fb5f42862971ac75b9935ae 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 7 103 2.3E-23 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TL08_12925 d10a6ae741c303174f791705b20ddedf 493 SUPERFAMILY SSF53067 7 248 4.21E-39 T 12-10-2018 TL08_12925 d10a6ae741c303174f791705b20ddedf 493 Gene3D G3DSA:3.30.420.40 2 238 2.0E-50 T 12-10-2018 TL08_12925 d10a6ae741c303174f791705b20ddedf 493 SUPERFAMILY SSF53067 253 488 7.67E-41 T 12-10-2018 TL08_12925 d10a6ae741c303174f791705b20ddedf 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 445 2.4E-22 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TL08_12925 d10a6ae741c303174f791705b20ddedf 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 245 4.3E-29 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TL08_12925 d10a6ae741c303174f791705b20ddedf 493 Gene3D G3DSA:3.30.420.40 240 492 5.7E-49 T 12-10-2018 TL08_12925 d10a6ae741c303174f791705b20ddedf 493 PIRSF PIRSF000538 4 492 1.2E-87 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TL08_15720 be97dfba52365e41908d39d1fa6778e7 215 SUPERFAMILY SSF46689 12 92 5.08E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_15720 be97dfba52365e41908d39d1fa6778e7 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 4.1E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15720 be97dfba52365e41908d39d1fa6778e7 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 6.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15720 be97dfba52365e41908d39d1fa6778e7 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 6.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15720 be97dfba52365e41908d39d1fa6778e7 215 Gene3D G3DSA:1.10.10.60 3 65 1.4E-16 T 12-10-2018 TL08_15720 be97dfba52365e41908d39d1fa6778e7 215 Gene3D G3DSA:1.10.357.10 66 206 1.2E-18 T 12-10-2018 TL08_15720 be97dfba52365e41908d39d1fa6778e7 215 SUPERFAMILY SSF48498 91 207 1.01E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_15720 be97dfba52365e41908d39d1fa6778e7 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_12805 33ccf80a03b3f277a43ea86fd71e687b 610 Gene3D G3DSA:3.40.50.300 344 598 1.1E-73 T 12-10-2018 TL08_12805 33ccf80a03b3f277a43ea86fd71e687b 610 SUPERFAMILY SSF90123 18 331 1.18E-62 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_12805 33ccf80a03b3f277a43ea86fd71e687b 610 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12805 33ccf80a03b3f277a43ea86fd71e687b 610 SMART SM00382 379 563 1.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12805 33ccf80a03b3f277a43ea86fd71e687b 610 Gene3D G3DSA:1.20.1560.10 3 331 1.0E-66 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_12805 33ccf80a03b3f277a43ea86fd71e687b 610 Pfam PF00005 ABC transporter 370 517 8.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12805 33ccf80a03b3f277a43ea86fd71e687b 610 Pfam PF00664 ABC transporter transmembrane region 31 299 5.0E-35 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_12805 33ccf80a03b3f277a43ea86fd71e687b 610 SUPERFAMILY SSF52540 351 585 1.95E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24630 e2f90629ddda20f4d4dc21c33a356ab1 466 SUPERFAMILY SSF103473 1 401 4.19E-46 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_24630 e2f90629ddda20f4d4dc21c33a356ab1 466 Gene3D G3DSA:1.20.1250.20 5 397 1.1E-37 T 12-10-2018 TL08_24630 e2f90629ddda20f4d4dc21c33a356ab1 466 Pfam PF05977 Transmembrane secretion effector 10 404 6.9E-30 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_06980 5ad030917ea778804689b1456e02f6d0 622 Pfam PF03703 Bacterial PH domain 141 222 3.7E-16 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_06980 5ad030917ea778804689b1456e02f6d0 622 Pfam PF03703 Bacterial PH domain 506 578 1.9E-6 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_27115 c5f5743adedae6132b41dd06701ab4be 332 Pfam PF02195 ParB-like nuclease domain 68 157 7.2E-26 T 12-10-2018 IPR003115 ParB/Sulfiredoxin TL08_27115 c5f5743adedae6132b41dd06701ab4be 332 Gene3D G3DSA:1.10.10.2830 144 257 4.3E-34 T 12-10-2018 TL08_27115 c5f5743adedae6132b41dd06701ab4be 332 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 65 242 1.3E-60 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TL08_27115 c5f5743adedae6132b41dd06701ab4be 332 SUPERFAMILY SSF110849 63 160 5.49E-28 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TL08_27115 c5f5743adedae6132b41dd06701ab4be 332 SUPERFAMILY SSF109709 149 258 3.66E-32 T 12-10-2018 TL08_27115 c5f5743adedae6132b41dd06701ab4be 332 Gene3D G3DSA:3.90.1530.30 80 142 4.7E-25 T 12-10-2018 TL08_27115 c5f5743adedae6132b41dd06701ab4be 332 SMART SM00470 67 157 1.9E-33 T 12-10-2018 IPR003115 ParB/Sulfiredoxin TL08_13505 117061246c0ed8a764597765f229e96c 320 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 305 4.7E-99 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 TL08_13505 117061246c0ed8a764597765f229e96c 320 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 1.3E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TL08_13505 117061246c0ed8a764597765f229e96c 320 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 1.3E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TL08_13505 117061246c0ed8a764597765f229e96c 320 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 111 125 1.3E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TL08_13505 117061246c0ed8a764597765f229e96c 320 SUPERFAMILY SSF53474 5 316 6.95E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13505 117061246c0ed8a764597765f229e96c 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 3.9E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_13505 117061246c0ed8a764597765f229e96c 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 3.9E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_13505 117061246c0ed8a764597765f229e96c 320 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 3.9E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_13505 117061246c0ed8a764597765f229e96c 320 PIRSF PIRSF006431 1 319 3.6E-115 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 TL08_13505 117061246c0ed8a764597765f229e96c 320 Pfam PF00561 alpha/beta hydrolase fold 35 300 6.1E-34 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_13505 117061246c0ed8a764597765f229e96c 320 Gene3D G3DSA:3.40.50.1820 1 319 1.1E-91 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_12895 380f0cc68a748714ad888f36546f95c3 343 Gene3D G3DSA:3.10.129.10 25 162 6.8E-14 T 12-10-2018 TL08_12895 380f0cc68a748714ad888f36546f95c3 343 Gene3D G3DSA:3.10.129.10 193 332 7.8E-16 T 12-10-2018 TL08_12895 380f0cc68a748714ad888f36546f95c3 343 SUPERFAMILY SSF54637 26 160 7.22E-14 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_12895 380f0cc68a748714ad888f36546f95c3 343 SUPERFAMILY SSF54637 200 329 5.19E-12 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_12895 380f0cc68a748714ad888f36546f95c3 343 Pfam PF01575 MaoC like domain 202 298 8.5E-5 T 12-10-2018 IPR002539 MaoC-like dehydratase domain TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 359 374 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 PIRSF PIRSF001604 26 705 1.1E-229 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Pfam PF12826 Helix-hairpin-helix motif 545 608 7.4E-21 T 12-10-2018 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 141 170 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 349 426 2.9E-31 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 SUPERFAMILY SSF52113 629 701 1.54E-15 T 12-10-2018 IPR036420 BRCT domain superfamily TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 SMART SM00292 627 704 1.9E-8 T 12-10-2018 IPR001357 BRCT domain TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Gene3D G3DSA:2.40.50.140 346 417 1.3E-28 T 12-10-2018 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 SUPERFAMILY SSF47781 431 619 2.34E-47 T 12-10-2018 IPR010994 RuvA domain 2-like TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 33 346 1.4E-117 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Gene3D G3DSA:1.10.150.20 461 539 1.1E-10 T 12-10-2018 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 629 696 5.1E-9 T 12-10-2018 IPR001357 BRCT domain TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 39 696 1.2E-235 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Gene3D G3DSA:3.40.50.10190 625 706 1.7E-21 T 12-10-2018 IPR036420 BRCT domain superfamily TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 SUPERFAMILY SSF56091 32 344 1.14E-111 T 12-10-2018 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Gene3D G3DSA:1.10.287.610 22 95 3.7E-25 T 12-10-2018 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 435 463 1.1E-7 T 12-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 SUPERFAMILY SSF50249 345 428 3.43E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 SMART SM00532 31 477 1.7E-254 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Hamap MF_01588 DNA ligase [ligA]. 30 701 50.106 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Gene3D G3DSA:2.20.70.80 419 458 4.0E-7 T 12-10-2018 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Gene3D G3DSA:3.30.470.90 96 345 1.4E-99 T 12-10-2018 TL08_22850 ca2619f1a7445aba3d7aad5b189f4853 738 Gene3D G3DSA:1.10.150.20 540 621 2.8E-28 T 12-10-2018 TL08_09345 17981ce802029cda70a9e2b39a81a001 563 Gene3D G3DSA:3.10.20.580 460 563 4.7E-15 T 12-10-2018 TL08_09345 17981ce802029cda70a9e2b39a81a001 563 Gene3D G3DSA:3.40.50.10710 218 376 7.6E-168 T 12-10-2018 TL08_09345 17981ce802029cda70a9e2b39a81a001 563 PIRSF PIRSF004803 15 563 5.0E-195 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 TL08_09345 17981ce802029cda70a9e2b39a81a001 563 Hamap MF_01491 Ribonuclease J [rnj]. 15 563 40.273 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 TL08_09345 17981ce802029cda70a9e2b39a81a001 563 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 375 403 - T 12-10-2018 IPR001587 Ribonuclease J, conserved site TL08_09345 17981ce802029cda70a9e2b39a81a001 563 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 372 419 2.6E-10 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TL08_09345 17981ce802029cda70a9e2b39a81a001 563 Pfam PF12706 Beta-lactamase superfamily domain 61 179 2.2E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_09345 17981ce802029cda70a9e2b39a81a001 563 SMART SM00849 32 226 3.1E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_09345 17981ce802029cda70a9e2b39a81a001 563 SUPERFAMILY SSF56281 20 435 5.46E-93 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_09345 17981ce802029cda70a9e2b39a81a001 563 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 21 560 5.2E-146 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 TL08_09345 17981ce802029cda70a9e2b39a81a001 563 Gene3D G3DSA:3.60.15.10 21 447 7.6E-168 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_15765 1e3a324cc3b0277c32aa1195c97b39c3 645 Pfam PF00326 Prolyl oligopeptidase family 421 637 4.7E-45 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_15765 1e3a324cc3b0277c32aa1195c97b39c3 645 Gene3D G3DSA:3.40.50.1820 332 644 1.3E-76 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15765 1e3a324cc3b0277c32aa1195c97b39c3 645 SUPERFAMILY SSF53474 379 636 7.11E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15765 1e3a324cc3b0277c32aa1195c97b39c3 645 Gene3D G3DSA:2.120.10.30 5 188 5.9E-13 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_15765 1e3a324cc3b0277c32aa1195c97b39c3 645 SUPERFAMILY SSF82171 26 358 2.62E-17 T 12-10-2018 TL08_26610 cfee46ffd42648f6fe1c75b7ebdbebff 327 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 17 307 2.9E-50 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TL08_26610 cfee46ffd42648f6fe1c75b7ebdbebff 327 SUPERFAMILY SSF161111 16 228 3.79E-38 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TL08_26610 cfee46ffd42648f6fe1c75b7ebdbebff 327 SUPERFAMILY SSF160240 232 304 8.5E-6 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TL08_26610 cfee46ffd42648f6fe1c75b7ebdbebff 327 Pfam PF01545 Cation efflux family 18 226 3.5E-34 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TL08_26610 cfee46ffd42648f6fe1c75b7ebdbebff 327 Gene3D G3DSA:1.20.1510.10 15 226 2.4E-34 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 Gene3D G3DSA:1.25.40.10 694 987 1.8E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 SUPERFAMILY SSF48452 845 972 3.95E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 PRINTS PR00364 Disease resistance protein signature 347 361 5.7E-5 T 12-10-2018 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 PRINTS PR00364 Disease resistance protein signature 284 299 5.7E-5 T 12-10-2018 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 PRINTS PR00364 Disease resistance protein signature 437 451 5.7E-5 T 12-10-2018 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 Pfam PF03704 Bacterial transcriptional activator domain 98 245 1.7E-34 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 SMART SM00862 18 91 2.3E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 SMART SM01043 98 245 6.6E-38 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 Pfam PF00486 Transcriptional regulatory protein, C terminal 29 91 5.2E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 Gene3D G3DSA:1.25.40.10 95 261 4.3E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 Gene3D G3DSA:1.10.10.10 1 94 5.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 SUPERFAMILY SSF48452 94 263 3.79E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 SUPERFAMILY SSF52540 252 500 3.59E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 Gene3D G3DSA:3.40.50.300 262 392 3.6E-5 T 12-10-2018 TL08_21145 61610423dbb96bf7c44d8b5bb8b50d3c 991 SUPERFAMILY SSF46894 5 91 1.11E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_14015 44014e97b627cdc98e970491763c35d4 658 Gene3D G3DSA:1.20.120.850 423 646 2.4E-74 T 12-10-2018 TL08_14015 44014e97b627cdc98e970491763c35d4 658 Gene3D G3DSA:3.40.50.300 408 611 2.4E-74 T 12-10-2018 TL08_14015 44014e97b627cdc98e970491763c35d4 658 SMART SM00487 175 373 2.8E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_14015 44014e97b627cdc98e970491763c35d4 658 Pfam PF00176 SNF2 family N-terminal domain 202 467 3.2E-53 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 TL08_14015 44014e97b627cdc98e970491763c35d4 658 SMART SM00490 511 597 1.2E-18 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_14015 44014e97b627cdc98e970491763c35d4 658 Gene3D G3DSA:3.40.50.10810 153 401 2.3E-62 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily TL08_14015 44014e97b627cdc98e970491763c35d4 658 Pfam PF00271 Helicase conserved C-terminal domain 482 597 6.0E-13 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_14015 44014e97b627cdc98e970491763c35d4 658 SUPERFAMILY SSF52540 403 653 7.74E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14015 44014e97b627cdc98e970491763c35d4 658 SUPERFAMILY SSF52540 159 401 2.44E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10740 3fe8674c4fccd7c0be30fa5da3fda20e 129 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 126 1.0E-49 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TL08_10740 3fe8674c4fccd7c0be30fa5da3fda20e 129 Pfam PF01597 Glycine cleavage H-protein 8 126 2.1E-43 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate TL08_10740 3fe8674c4fccd7c0be30fa5da3fda20e 129 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 38.218 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TL08_10740 3fe8674c4fccd7c0be30fa5da3fda20e 129 Gene3D G3DSA:2.40.50.100 2 129 4.4E-51 T 12-10-2018 TL08_10740 3fe8674c4fccd7c0be30fa5da3fda20e 129 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TL08_10740 3fe8674c4fccd7c0be30fa5da3fda20e 129 SUPERFAMILY SSF51230 4 126 7.85E-43 T 12-10-2018 IPR011053 Single hybrid motif TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 Gene3D G3DSA:3.40.50.10490 10 214 3.9E-91 T 12-10-2018 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 Pfam PF00318 Ribosomal protein S2 9 224 1.6E-96 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 PRINTS PR00395 Ribosomal protein S2 signature 196 210 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 PRINTS PR00395 Ribosomal protein S2 signature 87 104 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 PRINTS PR00395 Ribosomal protein S2 signature 37 46 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 PRINTS PR00395 Ribosomal protein S2 signature 6 24 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 PRINTS PR00395 Ribosomal protein S2 signature 175 186 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 PRINTS PR00395 Ribosomal protein S2 signature 158 175 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 Gene3D G3DSA:1.10.287.610 97 152 3.9E-91 T 12-10-2018 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 224 2.7E-109 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 SUPERFAMILY SSF52313 6 228 1.83E-93 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily TL08_08870 9ec8bba3172beafa3c9242a55f78e06e 286 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 231 42.523 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_01655 e41329fadb5156584d07e551999d6653 338 Gene3D G3DSA:3.40.50.620 32 250 7.1E-59 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_01655 e41329fadb5156584d07e551999d6653 338 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 24 326 18.557 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TL08_01655 e41329fadb5156584d07e551999d6653 338 Pfam PF09179 TilS substrate binding domain 271 332 1.2E-12 T 12-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TL08_01655 e41329fadb5156584d07e551999d6653 338 SUPERFAMILY SSF82829 229 331 1.57E-13 T 12-10-2018 TL08_01655 e41329fadb5156584d07e551999d6653 338 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 42 219 5.6E-37 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TL08_01655 e41329fadb5156584d07e551999d6653 338 Pfam PF01171 PP-loop family 42 216 2.9E-31 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TL08_01655 e41329fadb5156584d07e551999d6653 338 SUPERFAMILY SSF52402 39 248 6.28E-44 T 12-10-2018 TL08_07230 ca09c8e2dba133727bd9316f1e529956 335 Pfam PF05746 DALR anticodon binding domain 223 335 5.3E-12 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TL08_07230 ca09c8e2dba133727bd9316f1e529956 335 SMART SM01016 4 92 6.9E-11 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_07230 ca09c8e2dba133727bd9316f1e529956 335 SUPERFAMILY SSF55190 38 112 3.01E-10 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TL08_07230 ca09c8e2dba133727bd9316f1e529956 335 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 29 90 3.5E-9 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TL08_07230 ca09c8e2dba133727bd9316f1e529956 335 Gene3D G3DSA:3.30.1360.70 3 107 2.9E-9 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TL08_07230 ca09c8e2dba133727bd9316f1e529956 335 SUPERFAMILY SSF47323 177 335 5.67E-13 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_07230 ca09c8e2dba133727bd9316f1e529956 335 SMART SM00836 183 335 6.1E-9 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TL08_26320 588002680fc5d57e43fb57fadc1dd104 547 PRINTS PR00175 Sodium/alanine symporter signature 283 302 8.7E-42 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TL08_26320 588002680fc5d57e43fb57fadc1dd104 547 PRINTS PR00175 Sodium/alanine symporter signature 489 509 8.7E-42 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TL08_26320 588002680fc5d57e43fb57fadc1dd104 547 PRINTS PR00175 Sodium/alanine symporter signature 373 391 8.7E-42 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TL08_26320 588002680fc5d57e43fb57fadc1dd104 547 PRINTS PR00175 Sodium/alanine symporter signature 428 450 8.7E-42 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TL08_26320 588002680fc5d57e43fb57fadc1dd104 547 PRINTS PR00175 Sodium/alanine symporter signature 255 273 8.7E-42 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TL08_26320 588002680fc5d57e43fb57fadc1dd104 547 PRINTS PR00175 Sodium/alanine symporter signature 144 166 8.7E-42 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TL08_26320 588002680fc5d57e43fb57fadc1dd104 547 Pfam PF01235 Sodium:alanine symporter family 108 528 6.2E-127 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TL08_26320 588002680fc5d57e43fb57fadc1dd104 547 TIGRFAM TIGR00835 agcS: amino acid carrier protein 72 520 1.1E-107 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TL08_09425 a305893f56839ef5bc6555f83adcee4e 815 Gene3D G3DSA:3.10.620.30 371 545 5.7E-21 T 12-10-2018 TL08_09425 a305893f56839ef5bc6555f83adcee4e 815 SUPERFAMILY SSF54001 390 535 5.61E-31 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TL08_09425 a305893f56839ef5bc6555f83adcee4e 815 SMART SM00460 464 533 1.0E-17 T 12-10-2018 IPR002931 Transglutaminase-like TL08_09425 a305893f56839ef5bc6555f83adcee4e 815 Pfam PF01841 Transglutaminase-like superfamily 415 531 1.0E-23 T 12-10-2018 IPR002931 Transglutaminase-like TL08_00690 3bd3e5d591b0a8b20a3780d23ba64dd4 294 SUPERFAMILY SSF53448 5 226 4.69E-28 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00690 3bd3e5d591b0a8b20a3780d23ba64dd4 294 Gene3D G3DSA:3.90.550.10 2 265 1.4E-19 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00690 3bd3e5d591b0a8b20a3780d23ba64dd4 294 Pfam PF00535 Glycosyl transferase family 2 5 159 9.4E-15 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 Gene3D G3DSA:1.10.275.10 16 143 6.2E-50 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 Pfam PF00206 Lyase 23 347 3.4E-99 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 PRINTS PR00149 Fumarate lyase superfamily signature 276 303 1.6E-32 T 12-10-2018 IPR000362 Fumarate lyase family TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 PRINTS PR00149 Fumarate lyase superfamily signature 322 338 1.6E-32 T 12-10-2018 IPR000362 Fumarate lyase family TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 PRINTS PR00149 Fumarate lyase superfamily signature 185 203 1.6E-32 T 12-10-2018 IPR000362 Fumarate lyase family TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 1.6E-32 T 12-10-2018 IPR000362 Fumarate lyase family TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 Pfam PF10415 Fumarase C C-terminus 413 471 8.0E-21 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 PRINTS PR00145 Argininosuccinate lyase family signature 138 160 1.7E-6 T 12-10-2018 TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 PRINTS PR00145 Argininosuccinate lyase family signature 180 200 1.7E-6 T 12-10-2018 TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 PRINTS PR00145 Argininosuccinate lyase family signature 322 338 1.7E-6 T 12-10-2018 TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 SUPERFAMILY SSF48557 15 470 1.57E-141 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 Gene3D G3DSA:1.10.40.30 413 469 2.6E-24 T 12-10-2018 TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 Gene3D G3DSA:1.20.200.10 144 412 1.0E-109 T 12-10-2018 TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 Hamap MF_00743 Fumarate hydratase class II [fumC]. 15 472 80.059 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TL08_04150 e9b909a5e7b1abeacedb2aa495f43c4d 474 ProSitePatterns PS00163 Fumarate lyases signature. 322 331 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TL08_05380 f506507d9fb57b0eec6125e314ac2ac8 122 Gene3D G3DSA:1.10.10.10 1 79 2.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05380 f506507d9fb57b0eec6125e314ac2ac8 122 Pfam PF01022 Bacterial regulatory protein, arsR family 10 54 2.8E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_05380 f506507d9fb57b0eec6125e314ac2ac8 122 SMART SM00418 3 81 3.6E-24 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_05380 f506507d9fb57b0eec6125e314ac2ac8 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.0E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_05380 f506507d9fb57b0eec6125e314ac2ac8 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 2.0E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_05380 f506507d9fb57b0eec6125e314ac2ac8 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 2.0E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_05380 f506507d9fb57b0eec6125e314ac2ac8 122 SUPERFAMILY SSF46785 3 80 3.18E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 SUPERFAMILY SSF56420 34 199 7.2E-53 T 12-10-2018 IPR036821 Peptide deformylase superfamily TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 Hamap MF_00163 Peptide deformylase [def]. 35 202 28.173 T 12-10-2018 IPR023635 Peptide deformylase TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 Gene3D G3DSA:3.90.45.10 35 216 7.2E-53 T 12-10-2018 IPR036821 Peptide deformylase superfamily TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 40 199 1.0E-37 T 12-10-2018 IPR023635 Peptide deformylase TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 PIRSF PIRSF004749 21 213 1.3E-43 T 12-10-2018 IPR023635 Peptide deformylase TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 PRINTS PR01576 Peptide deformylase signature 67 96 1.5E-33 T 12-10-2018 IPR023635 Peptide deformylase TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 PRINTS PR01576 Peptide deformylase signature 129 140 1.5E-33 T 12-10-2018 IPR023635 Peptide deformylase TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 PRINTS PR01576 Peptide deformylase signature 141 159 1.5E-33 T 12-10-2018 IPR023635 Peptide deformylase TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 PRINTS PR01576 Peptide deformylase signature 160 189 1.5E-33 T 12-10-2018 IPR023635 Peptide deformylase TL08_13240 e1bd8f7a71eab697a2c5a6ee5e0e0018 219 Pfam PF01327 Polypeptide deformylase 37 192 3.1E-45 T 12-10-2018 IPR023635 Peptide deformylase TL08_22425 5f720917421c6c556adc6066dab4c762 178 Pfam PF12802 MarR family 51 111 5.3E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_22425 5f720917421c6c556adc6066dab4c762 178 SMART SM00347 45 148 8.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_22425 5f720917421c6c556adc6066dab4c762 178 Gene3D G3DSA:1.10.10.10 3 163 4.5E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22425 5f720917421c6c556adc6066dab4c762 178 SUPERFAMILY SSF46785 16 162 9.56E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_01965 7c89ba319007480abec6e9d62bbf4413 841 Gene3D G3DSA:3.30.70.1020 104 180 3.3E-50 T 12-10-2018 TL08_01965 7c89ba319007480abec6e9d62bbf4413 841 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 23 250 4.5E-38 T 12-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 TL08_01965 7c89ba319007480abec6e9d62bbf4413 841 Gene3D G3DSA:1.50.10.10 475 841 9.1E-81 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_01965 7c89ba319007480abec6e9d62bbf4413 841 Pfam PF00723 Glycosyl hydrolases family 15 481 836 4.7E-35 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 TL08_01965 7c89ba319007480abec6e9d62bbf4413 841 Gene3D G3DSA:3.40.50.1000 25 236 3.3E-50 T 12-10-2018 IPR023214 HAD superfamily TL08_01965 7c89ba319007480abec6e9d62bbf4413 841 SUPERFAMILY SSF56784 24 250 3.0E-36 T 12-10-2018 IPR036412 HAD-like superfamily TL08_01965 7c89ba319007480abec6e9d62bbf4413 841 SUPERFAMILY SSF48208 462 836 4.91E-90 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_01965 7c89ba319007480abec6e9d62bbf4413 841 Pfam PF02358 Trehalose-phosphatase 27 232 5.5E-35 T 12-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 TL08_27135 98f642808a4f2b93b8fb17b67a6442de 185 Pfam PF01424 R3H domain 128 181 3.8E-13 T 12-10-2018 IPR001374 R3H domain GO:0003676 TL08_27135 98f642808a4f2b93b8fb17b67a6442de 185 SMART SM00393 105 184 4.0E-19 T 12-10-2018 IPR001374 R3H domain GO:0003676 TL08_27135 98f642808a4f2b93b8fb17b67a6442de 185 Gene3D G3DSA:3.30.1370.50 120 185 2.7E-19 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 TL08_27135 98f642808a4f2b93b8fb17b67a6442de 185 SUPERFAMILY SSF82708 136 183 1.37E-9 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 TL08_27135 98f642808a4f2b93b8fb17b67a6442de 185 Gene3D G3DSA:3.30.300.20 36 119 4.8E-14 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_19740 6192061ec7826b76c300c4d1ca23abc6 260 Gene3D G3DSA:3.30.450.40 74 250 1.5E-57 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_19740 6192061ec7826b76c300c4d1ca23abc6 260 SUPERFAMILY SSF55781 57 244 2.7E-49 T 12-10-2018 TL08_19740 6192061ec7826b76c300c4d1ca23abc6 260 SMART SM00346 2 89 4.6E-23 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_19740 6192061ec7826b76c300c4d1ca23abc6 260 Pfam PF01614 Bacterial transcriptional regulator 117 241 5.4E-32 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_19740 6192061ec7826b76c300c4d1ca23abc6 260 SUPERFAMILY SSF46785 3 73 3.62E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_19740 6192061ec7826b76c300c4d1ca23abc6 260 Gene3D G3DSA:1.10.10.10 2 73 1.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19740 6192061ec7826b76c300c4d1ca23abc6 260 Pfam PF09339 IclR helix-turn-helix domain 4 52 3.4E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_21600 b80dd5d95875d60084da727046a192e4 289 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 42 280 4.3E-39 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TL08_21600 b80dd5d95875d60084da727046a192e4 289 Gene3D G3DSA:3.20.20.190 27 288 7.3E-74 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_21600 b80dd5d95875d60084da727046a192e4 289 SUPERFAMILY SSF51695 36 286 3.14E-71 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 PIRSF PIRSF001100 8 321 3.0E-82 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 SUPERFAMILY SSF51989 36 317 9.68E-86 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 PRINTS PR00733 Glycosyl hydrolase family 6 signature 99 112 6.9E-43 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 PRINTS PR00733 Glycosyl hydrolase family 6 signature 262 282 6.9E-43 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 PRINTS PR00733 Glycosyl hydrolase family 6 signature 56 75 6.9E-43 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 PRINTS PR00733 Glycosyl hydrolase family 6 signature 247 260 6.9E-43 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 PRINTS PR00733 Glycosyl hydrolase family 6 signature 215 225 6.9E-43 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 PRINTS PR00733 Glycosyl hydrolase family 6 signature 127 142 6.9E-43 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 PRINTS PR00733 Glycosyl hydrolase family 6 signature 184 197 6.9E-43 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 PRINTS PR00733 Glycosyl hydrolase family 6 signature 286 300 6.9E-43 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 Gene3D G3DSA:3.20.20.40 34 320 2.2E-107 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 104 120 - T 12-10-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 TL08_11450 d34e21cad88e55e2ff3eab32f4b2299e 322 Pfam PF01341 Glycosyl hydrolases family 6 44 304 1.9E-65 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_26355 c1b97713d68be6f4e570cb57342b4818 503 Pfam PF00561 alpha/beta hydrolase fold 97 474 1.1E-27 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_26355 c1b97713d68be6f4e570cb57342b4818 503 SUPERFAMILY SSF53474 76 472 2.79E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16710 5ac6aaf126e050360f065f31811ed866 261 SUPERFAMILY SSF100950 74 244 5.12E-27 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_16710 5ac6aaf126e050360f065f31811ed866 261 SMART SM00420 6 58 9.1E-15 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_16710 5ac6aaf126e050360f065f31811ed866 261 SUPERFAMILY SSF46785 4 63 6.84E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16710 5ac6aaf126e050360f065f31811ed866 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.7E-15 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_16710 5ac6aaf126e050360f065f31811ed866 261 SMART SM01134 72 242 3.2E-58 T 12-10-2018 TL08_16710 5ac6aaf126e050360f065f31811ed866 261 Pfam PF00455 DeoR C terminal sensor domain 74 241 7.0E-46 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain TL08_16710 5ac6aaf126e050360f065f31811ed866 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.3E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_16710 5ac6aaf126e050360f065f31811ed866 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.3E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_16710 5ac6aaf126e050360f065f31811ed866 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TL08_16710 5ac6aaf126e050360f065f31811ed866 261 Gene3D G3DSA:3.40.50.1360 72 241 2.2E-6 T 12-10-2018 TL08_10395 e62d036990075a6f7c1f254d441a7854 206 Pfam PF01174 SNO glutamine amidotransferase family 9 203 4.5E-57 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_10395 e62d036990075a6f7c1f254d441a7854 206 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 7 200 1.1E-70 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_10395 e62d036990075a6f7c1f254d441a7854 206 Gene3D G3DSA:3.40.50.880 4 206 3.0E-70 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_10395 e62d036990075a6f7c1f254d441a7854 206 ProSitePatterns PS01236 PdxT/SNO family family signature. 44 54 - T 12-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_10395 e62d036990075a6f7c1f254d441a7854 206 PIRSF PIRSF005639 1 206 1.5E-69 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_10395 e62d036990075a6f7c1f254d441a7854 206 SUPERFAMILY SSF52317 6 203 5.16E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_10395 e62d036990075a6f7c1f254d441a7854 206 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 7 202 37.824 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TL08_22870 577da62c3fd985f972ccfd65c68051a1 318 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 32 310 2.9E-61 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_22870 577da62c3fd985f972ccfd65c68051a1 318 Gene3D G3DSA:3.40.50.1100 27 314 5.9E-81 T 12-10-2018 TL08_22870 577da62c3fd985f972ccfd65c68051a1 318 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TL08_22870 577da62c3fd985f972ccfd65c68051a1 318 Gene3D G3DSA:3.40.50.1100 61 154 5.9E-81 T 12-10-2018 TL08_22870 577da62c3fd985f972ccfd65c68051a1 318 SUPERFAMILY SSF53686 22 314 4.98E-67 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_10035 fa69f3fe3e5dac6813604e0c94a8888c 120 Gene3D G3DSA:1.10.10.10 3 106 6.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_10035 fa69f3fe3e5dac6813604e0c94a8888c 120 SUPERFAMILY SSF46785 4 89 2.51E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_10035 fa69f3fe3e5dac6813604e0c94a8888c 120 Pfam PF12840 Helix-turn-helix domain 5 64 5.3E-14 T 12-10-2018 TL08_10035 fa69f3fe3e5dac6813604e0c94a8888c 120 SMART SM00418 5 87 6.9E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_10035 fa69f3fe3e5dac6813604e0c94a8888c 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 8.3E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_10035 fa69f3fe3e5dac6813604e0c94a8888c 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 8.3E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_10035 fa69f3fe3e5dac6813604e0c94a8888c 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 8.3E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_21355 039a89f50c74f4fefbe91897cad893a0 287 SMART SM00342 186 270 6.3E-11 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_21355 039a89f50c74f4fefbe91897cad893a0 287 SUPERFAMILY SSF46689 222 272 8.96E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_21355 039a89f50c74f4fefbe91897cad893a0 287 Gene3D G3DSA:1.10.10.60 173 274 2.7E-19 T 12-10-2018 TL08_21355 039a89f50c74f4fefbe91897cad893a0 287 Pfam PF12833 Helix-turn-helix domain 195 271 2.3E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_05340 dac789d378e8044b4c9202a3eac121da 139 SUPERFAMILY SSF54593 4 135 7.16E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_05340 dac789d378e8044b4c9202a3eac121da 139 Gene3D G3DSA:3.10.180.10 9 137 1.6E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_05340 dac789d378e8044b4c9202a3eac121da 139 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 129 2.4E-12 T 12-10-2018 IPR028973 PhnB-like TL08_23270 fe393016c5bcdb071a14e4cac38a91fd 231 SUPERFAMILY SSF53271 142 224 1.75E-12 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 SMART SM00490 423 500 1.2E-12 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 SMART SM00487 178 353 1.7E-22 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 Gene3D G3DSA:3.40.50.300 174 353 1.1E-36 T 12-10-2018 TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 SUPERFAMILY SSF52540 148 345 2.28E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 Pfam PF04851 Type III restriction enzyme, res subunit 181 326 1.9E-14 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 Pfam PF13625 Helicase conserved C-terminal domain 6 133 2.0E-45 T 12-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 356 378 2.4E-34 T 12-10-2018 TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 456 474 2.4E-34 T 12-10-2018 TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 475 500 2.4E-34 T 12-10-2018 TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 291 311 2.4E-34 T 12-10-2018 TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 191 213 2.4E-34 T 12-10-2018 TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 540 1.1E-44 T 12-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 SUPERFAMILY SSF52540 284 527 1.21E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25350 d9ffe44d236948f77298f955ca1f2815 553 Gene3D G3DSA:3.40.50.300 354 546 1.5E-47 T 12-10-2018 TL08_00445 9f49c71489ee9d66e92c2137c67a88aa 482 SUPERFAMILY SSF81995 4 68 1.57E-7 T 12-10-2018 TL08_01065 b4501948c1d319177149f8cddf1cf736 703 Gene3D G3DSA:1.10.8.60 7 237 5.0E-93 T 12-10-2018 TL08_01065 b4501948c1d319177149f8cddf1cf736 703 SUPERFAMILY SSF52540 32 221 3.55E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01065 b4501948c1d319177149f8cddf1cf736 703 SMART SM00382 36 180 6.7E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01065 b4501948c1d319177149f8cddf1cf736 703 Gene3D G3DSA:1.20.272.10 244 366 5.0E-7 T 12-10-2018 TL08_01065 b4501948c1d319177149f8cddf1cf736 703 Pfam PF13177 DNA polymerase III, delta subunit 19 177 2.2E-38 T 12-10-2018 TL08_01065 b4501948c1d319177149f8cddf1cf736 703 Gene3D G3DSA:3.40.50.300 12 178 5.0E-93 T 12-10-2018 TL08_01065 b4501948c1d319177149f8cddf1cf736 703 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 4 362 9.1E-113 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 TL08_01065 b4501948c1d319177149f8cddf1cf736 703 SUPERFAMILY SSF48019 246 363 2.98E-20 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TL08_01065 b4501948c1d319177149f8cddf1cf736 703 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 235 364 1.1E-14 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 TL08_10185 9c656ad6a259d864030cb86d9937f3f2 209 SMART SM01012 150 205 3.4E-25 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 TL08_10185 9c656ad6a259d864030cb86d9937f3f2 209 Pfam PF00072 Response regulator receiver domain 25 134 2.2E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_10185 9c656ad6a259d864030cb86d9937f3f2 209 SUPERFAMILY SSF52172 21 205 1.14E-58 T 12-10-2018 IPR011006 CheY-like superfamily TL08_10185 9c656ad6a259d864030cb86d9937f3f2 209 Gene3D G3DSA:3.40.50.2300 11 151 2.4E-37 T 12-10-2018 TL08_10185 9c656ad6a259d864030cb86d9937f3f2 209 Gene3D G3DSA:1.10.10.10 152 209 2.9E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_10185 9c656ad6a259d864030cb86d9937f3f2 209 PIRSF PIRSF036382 13 209 4.9E-74 T 12-10-2018 IPR008327 Signal transduction response regulator, antiterminator TL08_10185 9c656ad6a259d864030cb86d9937f3f2 209 SMART SM00448 23 134 7.6E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_10185 9c656ad6a259d864030cb86d9937f3f2 209 Pfam PF03861 ANTAR domain 152 205 1.4E-22 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 TL08_10475 32b362ad22192306016a15adf3711aa8 86 SUPERFAMILY SSF47336 4 81 6.81E-15 T 12-10-2018 IPR036736 ACP-like superfamily TL08_10475 32b362ad22192306016a15adf3711aa8 86 SMART SM00823 Phosphopantetheine attachment site 10 81 0.0052 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_10475 32b362ad22192306016a15adf3711aa8 86 Gene3D G3DSA:1.10.1200.10 1 82 1.5E-20 T 12-10-2018 IPR036736 ACP-like superfamily TL08_10475 32b362ad22192306016a15adf3711aa8 86 Pfam PF00550 Phosphopantetheine attachment site 7 77 4.4E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_21875 8031078b7d502398a4ef6f19cd8978c5 296 Pfam PF08338 Domain of unknown function (DUF1731) 246 290 8.7E-16 T 12-10-2018 IPR013549 Domain of unknown function DUF1731 TL08_21875 8031078b7d502398a4ef6f19cd8978c5 296 Gene3D G3DSA:3.40.50.720 1 284 3.5E-72 T 12-10-2018 TL08_21875 8031078b7d502398a4ef6f19cd8978c5 296 SUPERFAMILY SSF51735 1 283 8.12E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_21875 8031078b7d502398a4ef6f19cd8978c5 296 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 289 2.3E-96 T 12-10-2018 IPR010099 Epimerase family protein SDR39U1 TL08_21875 8031078b7d502398a4ef6f19cd8978c5 296 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 120 1.5E-8 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_24975 8876e1d51cf87ed75be0db1789508d6b 539 Gene3D G3DSA:2.40.50.900 73 156 3.0E-10 T 12-10-2018 TL08_24975 8876e1d51cf87ed75be0db1789508d6b 539 Gene3D G3DSA:2.40.50.910 271 355 7.2E-9 T 12-10-2018 TL08_24975 8876e1d51cf87ed75be0db1789508d6b 539 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 496 1.6E-90 T 12-10-2018 IPR007795 Type VII secretion system EccB TL08_24975 8876e1d51cf87ed75be0db1789508d6b 539 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 4 509 3.3E-112 T 12-10-2018 IPR007795 Type VII secretion system EccB TL08_11845 e2af38423a92d816788b17f4a8a91f27 79 Pfam PF04149 Domain of unknown function (DUF397) 17 69 1.7E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_20905 2e803821444c3fd68e66f485bddedf01 395 Gene3D G3DSA:3.40.1660.10 15 309 4.4E-27 T 12-10-2018 TL08_20905 2e803821444c3fd68e66f485bddedf01 395 Gene3D G3DSA:3.30.1870.10 42 119 4.4E-27 T 12-10-2018 TL08_20905 2e803821444c3fd68e66f485bddedf01 395 Pfam PF05139 Erythromycin esterase 42 359 3.2E-46 T 12-10-2018 IPR007815 Erythromycin esterase GO:0046677 TL08_20905 2e803821444c3fd68e66f485bddedf01 395 SUPERFAMILY SSF159501 15 330 1.36E-58 T 12-10-2018 TL08_20905 2e803821444c3fd68e66f485bddedf01 395 Gene3D G3DSA:1.20.1440.30 120 260 4.4E-27 T 12-10-2018 TL08_16945 eb5ef8cdbd34f9c31e7edd79d83ad323 327 SUPERFAMILY SSF161098 85 312 3.79E-57 T 12-10-2018 IPR035906 MetI-like superfamily TL08_16945 eb5ef8cdbd34f9c31e7edd79d83ad323 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 313 4.5E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_16945 eb5ef8cdbd34f9c31e7edd79d83ad323 327 Gene3D G3DSA:1.10.3720.10 81 322 1.0E-63 T 12-10-2018 IPR035906 MetI-like superfamily TL08_12235 bcea2fa49e9a45830b03abeb90a16bca 265 Gene3D G3DSA:1.10.1760.20 70 263 2.7E-7 T 12-10-2018 TL08_12235 bcea2fa49e9a45830b03abeb90a16bca 265 Pfam PF12822 ECF transporter, substrate-specific component 79 247 3.2E-15 T 12-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 TL08_12235 bcea2fa49e9a45830b03abeb90a16bca 265 PIRSF PIRSF037395 9 265 6.3E-91 T 12-10-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 TL08_04690 d0efb2969c72f149ac3ada68b2edda89 317 SUPERFAMILY SSF161098 32 306 7.98E-48 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04690 d0efb2969c72f149ac3ada68b2edda89 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 304 1.1E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_04690 d0efb2969c72f149ac3ada68b2edda89 317 Gene3D G3DSA:1.10.3720.10 26 304 3.3E-52 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04260 d0f9c93e730a367d052d00c7a6989d72 200 Gene3D G3DSA:3.40.50.150 3 197 8.1E-54 T 12-10-2018 TL08_04260 d0f9c93e730a367d052d00c7a6989d72 200 Pfam PF13649 Methyltransferase domain 46 136 6.2E-19 T 12-10-2018 TL08_04260 d0f9c93e730a367d052d00c7a6989d72 200 SUPERFAMILY SSF53335 4 184 5.41E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_20560 99959821482816c0e75770a588a2b965 142 Pfam PF01641 SelR domain 19 138 6.8E-50 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 TL08_20560 99959821482816c0e75770a588a2b965 142 SUPERFAMILY SSF51316 14 141 1.83E-53 T 12-10-2018 IPR011057 Mss4-like superfamily TL08_20560 99959821482816c0e75770a588a2b965 142 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 15 141 2.5E-47 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 TL08_20560 99959821482816c0e75770a588a2b965 142 Gene3D G3DSA:2.170.150.20 3 142 1.4E-56 T 12-10-2018 TL08_01045 4490e7d87df4593633ff61d0b30882e5 500 SUPERFAMILY SSF52540 267 479 2.44E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01045 4490e7d87df4593633ff61d0b30882e5 500 SUPERFAMILY SSF52540 5 227 2.11E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01045 4490e7d87df4593633ff61d0b30882e5 500 Gene3D G3DSA:3.40.50.300 256 497 7.2E-43 T 12-10-2018 TL08_01045 4490e7d87df4593633ff61d0b30882e5 500 SMART SM00382 30 217 4.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01045 4490e7d87df4593633ff61d0b30882e5 500 SMART SM00382 279 472 4.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01045 4490e7d87df4593633ff61d0b30882e5 500 Pfam PF00005 ABC transporter 271 423 4.2E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_01045 4490e7d87df4593633ff61d0b30882e5 500 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_01045 4490e7d87df4593633ff61d0b30882e5 500 Gene3D G3DSA:3.40.50.300 2 244 5.7E-56 T 12-10-2018 TL08_01045 4490e7d87df4593633ff61d0b30882e5 500 Pfam PF00005 ABC transporter 21 170 5.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 Pfam PF00106 short chain dehydrogenase 12 194 1.6E-52 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 Gene3D G3DSA:3.40.50.720 7 256 3.2E-72 T 12-10-2018 TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.7E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 189 7.4E-4 T 12-10-2018 TL08_09055 6c734abfb09d6b1f7d89165659da4cb6 257 SUPERFAMILY SSF51735 7 255 7.59E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_04815 67872de50fb80dda6c6b64ca545653b0 108 SUPERFAMILY SSF46767 3 78 3.14E-14 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TL08_04815 67872de50fb80dda6c6b64ca545653b0 108 Gene3D G3DSA:1.10.10.10 2 99 6.6E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04815 67872de50fb80dda6c6b64ca545653b0 108 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 6 79 3.1E-14 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TL08_14780 0f96a773266a432f61e264aa0b15c5de 404 Gene3D G3DSA:3.20.20.140 64 361 1.3E-114 T 12-10-2018 TL08_14780 0f96a773266a432f61e264aa0b15c5de 404 Pfam PF01979 Amidohydrolase family 59 401 1.4E-40 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_14780 0f96a773266a432f61e264aa0b15c5de 404 SUPERFAMILY SSF51338 9 402 6.49E-15 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_14780 0f96a773266a432f61e264aa0b15c5de 404 Gene3D G3DSA:2.30.40.10 17 402 1.3E-114 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_14780 0f96a773266a432f61e264aa0b15c5de 404 SUPERFAMILY SSF51556 63 364 2.91E-76 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_18905 4e23bd8fef60ae10d9db5c39533ed10e 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 113 1.8E-4 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_18905 4e23bd8fef60ae10d9db5c39533ed10e 121 Gene3D G3DSA:3.10.180.10 1 120 1.4E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_18905 4e23bd8fef60ae10d9db5c39533ed10e 121 SUPERFAMILY SSF54593 1 118 8.46E-13 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03325 d2b97bd5df097ca8c6196342f2048dd8 467 Gene3D G3DSA:3.40.50.300 186 458 5.2E-34 T 12-10-2018 TL08_03325 d2b97bd5df097ca8c6196342f2048dd8 467 SUPERFAMILY SSF52540 196 445 2.55E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24370 293b30fde19b098d704a7b0fda327e33 209 SUPERFAMILY SSF160631 22 165 8.76E-11 T 12-10-2018 TL08_24370 293b30fde19b098d704a7b0fda327e33 209 SMART SM00860 28 164 5.6E-5 T 12-10-2018 IPR018958 Knr4/Smi1-like domain TL08_24370 293b30fde19b098d704a7b0fda327e33 209 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 28 146 1.5E-8 T 12-10-2018 IPR018958 Knr4/Smi1-like domain TL08_24370 293b30fde19b098d704a7b0fda327e33 209 Gene3D G3DSA:3.40.1580.10 19 171 4.8E-6 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily TL08_16175 56bb73fc7fae432a339ca5b1a2c13cde 336 Gene3D G3DSA:3.40.190.150 45 322 8.8E-69 T 12-10-2018 TL08_16175 56bb73fc7fae432a339ca5b1a2c13cde 336 Gene3D G3DSA:3.40.190.10 140 258 8.8E-69 T 12-10-2018 TL08_16175 56bb73fc7fae432a339ca5b1a2c13cde 336 SUPERFAMILY SSF53850 46 287 4.55E-12 T 12-10-2018 TL08_16175 56bb73fc7fae432a339ca5b1a2c13cde 336 PIRSF PIRSF017082 5 331 1.1E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TL08_16175 56bb73fc7fae432a339ca5b1a2c13cde 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 61 326 1.2E-38 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TL08_12590 e9395b31a549dc7561b1378718f6377f 419 Pfam PF13458 Periplasmic binding protein 48 390 2.5E-53 T 12-10-2018 IPR028081 Leucine-binding protein domain TL08_12590 e9395b31a549dc7561b1378718f6377f 419 Gene3D G3DSA:3.40.50.2300 42 381 3.0E-114 T 12-10-2018 TL08_12590 e9395b31a549dc7561b1378718f6377f 419 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 71 87 6.3E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TL08_12590 e9395b31a549dc7561b1378718f6377f 419 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 6.3E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TL08_12590 e9395b31a549dc7561b1378718f6377f 419 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 302 315 6.3E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TL08_12590 e9395b31a549dc7561b1378718f6377f 419 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 90 108 6.3E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TL08_12590 e9395b31a549dc7561b1378718f6377f 419 SUPERFAMILY SSF53822 48 404 4.71E-49 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_12590 e9395b31a549dc7561b1378718f6377f 419 Gene3D G3DSA:3.40.50.2300 161 390 3.0E-114 T 12-10-2018 TL08_09570 a171582d49d09d60875b937f201a4622 309 Gene3D G3DSA:3.10.290.10 4 66 7.1E-7 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TL08_09570 a171582d49d09d60875b937f201a4622 309 SMART SM00363 16 75 0.006 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_09570 a171582d49d09d60875b937f201a4622 309 Gene3D G3DSA:3.30.2350.10 83 309 4.2E-71 T 12-10-2018 TL08_09570 a171582d49d09d60875b937f201a4622 309 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 136 150 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_09570 a171582d49d09d60875b937f201a4622 309 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 305 1.1E-84 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_09570 a171582d49d09d60875b937f201a4622 309 Pfam PF00849 RNA pseudouridylate synthase 91 244 1.1E-34 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_09570 a171582d49d09d60875b937f201a4622 309 SUPERFAMILY SSF55120 77 306 4.48E-71 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_13685 63e1b1b9cecf70c011c010ec21f5baf5 320 Pfam PF04616 Glycosyl hydrolases family 43 36 310 1.6E-43 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 TL08_13685 63e1b1b9cecf70c011c010ec21f5baf5 320 Gene3D G3DSA:2.115.10.20 35 320 1.4E-85 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_13685 63e1b1b9cecf70c011c010ec21f5baf5 320 SUPERFAMILY SSF75005 31 312 5.42E-63 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 213 8.7E-50 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 PRINTS PR00301 70kDa heat shock protein signature 408 428 5.6E-5 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.6E-5 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 PRINTS PR00301 70kDa heat shock protein signature 378 394 5.6E-5 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 337 358 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 PIRSF PIRSF000538 1 465 2.9E-87 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 243 425 4.7E-27 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 TIGRFAM TIGR01312 XylB: xylulokinase 5 431 2.9E-126 T 12-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 Gene3D G3DSA:3.30.420.40 237 468 8.4E-68 T 12-10-2018 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 SUPERFAMILY SSF53067 237 428 1.5E-41 T 12-10-2018 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 SUPERFAMILY SSF53067 4 236 4.89E-54 T 12-10-2018 TL08_23965 6badaea62c3753f26c09dcf0ec6ef3b4 476 Gene3D G3DSA:3.30.420.40 1 235 6.0E-82 T 12-10-2018 TL08_26575 a0c78958113676dcf77a19b7afa059b2 117 Gene3D G3DSA:1.10.1660.10 1 117 5.8E-29 T 12-10-2018 TL08_26575 a0c78958113676dcf77a19b7afa059b2 117 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.9E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26575 a0c78958113676dcf77a19b7afa059b2 117 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.9E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26575 a0c78958113676dcf77a19b7afa059b2 117 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.9E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26575 a0c78958113676dcf77a19b7afa059b2 117 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26575 a0c78958113676dcf77a19b7afa059b2 117 SUPERFAMILY SSF46955 1 113 2.71E-26 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_26575 a0c78958113676dcf77a19b7afa059b2 117 Pfam PF13411 MerR HTH family regulatory protein 1 67 8.5E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26575 a0c78958113676dcf77a19b7afa059b2 117 SMART SM00422 1 69 2.4E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_18680 59866d7962d501ec72af3194a6bb2cf6 141 Gene3D G3DSA:2.30.31.20 2 137 4.1E-46 T 12-10-2018 IPR038658 Sporulation-specific cell division protein SsgB superfamily TL08_18680 59866d7962d501ec72af3194a6bb2cf6 141 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 26 122 3.1E-35 T 12-10-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 TL08_17400 291867dfa3baef9fad7ecb7d29ed1ca1 476 SUPERFAMILY SSF100950 68 299 2.39E-35 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_17400 291867dfa3baef9fad7ecb7d29ed1ca1 476 Gene3D G3DSA:3.40.50.10420 135 283 7.6E-9 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TL08_17400 291867dfa3baef9fad7ecb7d29ed1ca1 476 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 23 460 1.4E-139 T 12-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 TL08_17400 291867dfa3baef9fad7ecb7d29ed1ca1 476 Pfam PF13183 4Fe-4S dicluster domain 314 384 4.2E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TL08_17400 291867dfa3baef9fad7ecb7d29ed1ca1 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 317 328 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TL08_17400 291867dfa3baef9fad7ecb7d29ed1ca1 476 Gene3D G3DSA:1.10.1060.10 307 413 2.9E-6 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TL08_17400 291867dfa3baef9fad7ecb7d29ed1ca1 476 SUPERFAMILY SSF54862 294 398 1.51E-14 T 12-10-2018 TL08_17400 291867dfa3baef9fad7ecb7d29ed1ca1 476 Pfam PF11870 Domain of unknown function (DUF3390) 402 473 4.0E-8 T 12-10-2018 IPR024569 4Fe-4S binding protein, C-terminal TL08_17400 291867dfa3baef9fad7ecb7d29ed1ca1 476 Pfam PF02589 LUD domain 74 297 2.8E-47 T 12-10-2018 IPR003741 LUD domain TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 SUPERFAMILY SSF52402 4 185 4.44E-31 T 12-10-2018 TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 473 79.384 T 12-10-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 SUPERFAMILY SSF69864 190 434 3.92E-74 T 12-10-2018 TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 Gene3D G3DSA:3.40.50.620 14 191 6.6E-113 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 Gene3D G3DSA:1.10.287.400 377 438 3.4E-27 T 12-10-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 Gene3D G3DSA:3.90.1260.10 74 367 6.6E-113 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 Pfam PF00764 Arginosuccinate synthase 16 394 3.9E-56 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TL08_16345 063de03f7cab94d5cf2c79cde9bf9abb 482 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 2.8E-138 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TL08_14975 417585f3351990e337fea5d95cd4ea26 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 3.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_14975 417585f3351990e337fea5d95cd4ea26 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 3.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_14975 417585f3351990e337fea5d95cd4ea26 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 3.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_14975 417585f3351990e337fea5d95cd4ea26 315 Gene3D G3DSA:3.40.190.10 98 294 6.7E-48 T 12-10-2018 TL08_14975 417585f3351990e337fea5d95cd4ea26 315 Gene3D G3DSA:1.10.10.10 6 95 1.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_14975 417585f3351990e337fea5d95cd4ea26 315 Gene3D G3DSA:3.40.190.10 172 276 6.7E-48 T 12-10-2018 TL08_14975 417585f3351990e337fea5d95cd4ea26 315 Pfam PF03466 LysR substrate binding domain 98 300 4.7E-39 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_14975 417585f3351990e337fea5d95cd4ea26 315 SUPERFAMILY SSF53850 100 300 3.53E-36 T 12-10-2018 TL08_14975 417585f3351990e337fea5d95cd4ea26 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 72 2.6E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_14975 417585f3351990e337fea5d95cd4ea26 315 SUPERFAMILY SSF46785 5 120 3.71E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_21210 b22cdc8ddf7a293b92570066f7ce5a77 371 Gene3D G3DSA:3.20.20.70 1 368 1.2E-129 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_21210 b22cdc8ddf7a293b92570066f7ce5a77 371 SUPERFAMILY SSF51395 1 364 2.41E-117 T 12-10-2018 TL08_21210 b22cdc8ddf7a293b92570066f7ce5a77 371 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 350 4.5E-74 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 TL08_15935 ab03278947edf196bac2980c441b72ca 465 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 173 429 1.8E-20 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 TL08_15935 ab03278947edf196bac2980c441b72ca 465 Gene3D G3DSA:3.40.50.2000 274 437 2.3E-33 T 12-10-2018 TL08_15935 ab03278947edf196bac2980c441b72ca 465 Gene3D G3DSA:3.40.50.2000 11 273 9.0E-20 T 12-10-2018 TL08_15935 ab03278947edf196bac2980c441b72ca 465 SUPERFAMILY SSF53756 14 450 2.26E-60 T 12-10-2018 TL08_07370 487318d01ddb201afe253015229299dc 192 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 186 1.0E-56 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TL08_07370 487318d01ddb201afe253015229299dc 192 Gene3D G3DSA:1.20.1200.10 29 192 2.1E-58 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TL08_07370 487318d01ddb201afe253015229299dc 192 Pfam PF01923 Cobalamin adenosyltransferase 8 177 1.1E-55 T 12-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TL08_07370 487318d01ddb201afe253015229299dc 192 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 181 2.2E-50 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TL08_07370 487318d01ddb201afe253015229299dc 192 SUPERFAMILY SSF89028 6 186 1.28E-55 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TL08_20450 54fa4c23289f8be13298418af69c9966 421 Gene3D G3DSA:3.40.640.10 79 329 5.3E-134 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_20450 54fa4c23289f8be13298418af69c9966 421 Pfam PF00202 Aminotransferase class-III 38 418 7.3E-113 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_20450 54fa4c23289f8be13298418af69c9966 421 PIRSF PIRSF000521 2 187 4.9E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_20450 54fa4c23289f8be13298418af69c9966 421 PIRSF PIRSF000521 194 421 1.9E-26 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_20450 54fa4c23289f8be13298418af69c9966 421 Gene3D G3DSA:3.90.1150.10 33 409 5.3E-134 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_20450 54fa4c23289f8be13298418af69c9966 421 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 26 419 3.1E-140 T 12-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TL08_20450 54fa4c23289f8be13298418af69c9966 421 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 244 281 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_20450 54fa4c23289f8be13298418af69c9966 421 SUPERFAMILY SSF53383 25 419 4.62E-118 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_26125 6fe65d17f95689e95425ffd11c443719 337 PIRSF PIRSF017617 1 337 2.3E-104 T 12-10-2018 IPR023603 Threonine aldolase TL08_26125 6fe65d17f95689e95425ffd11c443719 337 SUPERFAMILY SSF53383 7 336 1.85E-90 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_26125 6fe65d17f95689e95425ffd11c443719 337 Pfam PF01212 Beta-eliminating lyase 8 291 2.5E-71 T 12-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 TL08_26125 6fe65d17f95689e95425ffd11c443719 337 Gene3D G3DSA:3.90.1150.10 255 337 1.6E-17 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_26125 6fe65d17f95689e95425ffd11c443719 337 Gene3D G3DSA:3.40.640.10 3 254 6.0E-75 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_26855 edf475e7ebd24d8e1b6cc8561288109a 150 Gene3D G3DSA:3.40.5.10 1 59 1.4E-21 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26855 edf475e7ebd24d8e1b6cc8561288109a 150 SUPERFAMILY SSF55658 1 55 3.49E-17 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal TL08_26855 edf475e7ebd24d8e1b6cc8561288109a 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26855 edf475e7ebd24d8e1b6cc8561288109a 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 2.1E-21 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26855 edf475e7ebd24d8e1b6cc8561288109a 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 3.5E-23 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal TL08_26855 edf475e7ebd24d8e1b6cc8561288109a 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 1.5E-34 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_26855 edf475e7ebd24d8e1b6cc8561288109a 150 Gene3D G3DSA:3.10.430.100 60 149 4.8E-22 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TL08_26855 edf475e7ebd24d8e1b6cc8561288109a 150 SUPERFAMILY SSF55653 57 148 3.4E-21 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TL08_26855 edf475e7ebd24d8e1b6cc8561288109a 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 24.955 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_25925 7a80467ca973b27346bea872d033b00b 287 Pfam PF00085 Thioredoxin 195 255 7.6E-5 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 TL08_25925 7a80467ca973b27346bea872d033b00b 287 Gene3D G3DSA:3.40.30.10 177 280 4.0E-8 T 12-10-2018 TL08_25925 7a80467ca973b27346bea872d033b00b 287 SUPERFAMILY SSF52833 192 280 1.74E-11 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 Gene3D G3DSA:2.60.40.10 549 661 1.5E-31 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 32 281 1.8E-49 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 PRINTS PR00133 Glycosyl hydrolase family 3 signature 114 130 7.6E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 PRINTS PR00133 Glycosyl hydrolase family 3 signature 215 233 7.6E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 PRINTS PR00133 Glycosyl hydrolase family 3 signature 68 87 7.6E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 PRINTS PR00133 Glycosyl hydrolase family 3 signature 145 161 7.6E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 PRINTS PR00133 Glycosyl hydrolase family 3 signature 32 48 7.6E-31 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 SUPERFAMILY SSF52279 310 550 4.18E-50 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 Pfam PF14310 Fibronectin type III-like domain 581 649 5.2E-24 T 12-10-2018 IPR026891 Fibronectin type III-like domain TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 SUPERFAMILY SSF51445 8 306 6.95E-89 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 Gene3D G3DSA:3.20.20.300 7 287 4.9E-102 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 SMART SM01217 581 651 3.4E-30 T 12-10-2018 IPR026891 Fibronectin type III-like domain TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 Gene3D G3DSA:3.40.50.1700 294 548 2.1E-72 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 TL08_18435 8378f99feb124057c66e0e155e73ea8d 748 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 310 547 7.6E-53 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TL08_01400 bfdb79a19d8d8648d028a02f788c5e64 310 SUPERFAMILY SSF46689 15 87 8.78E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_01400 bfdb79a19d8d8648d028a02f788c5e64 310 Gene3D G3DSA:3.40.50.10490 108 293 3.6E-46 T 12-10-2018 TL08_01400 bfdb79a19d8d8648d028a02f788c5e64 310 SUPERFAMILY SSF53697 108 286 6.82E-42 T 12-10-2018 TL08_01400 bfdb79a19d8d8648d028a02f788c5e64 310 Gene3D G3DSA:1.10.10.10 9 92 3.7E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_01400 bfdb79a19d8d8648d028a02f788c5e64 310 Pfam PF01380 SIS domain 142 269 3.1E-25 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TL08_01400 bfdb79a19d8d8648d028a02f788c5e64 310 Pfam PF01418 Helix-turn-helix domain, rpiR family 17 87 2.3E-19 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 TL08_12450 0fdcc05aa7483e8408ab8ec481846a9d 486 Pfam PF14315 Domain of unknown function (DUF4380) 53 345 2.2E-12 T 12-10-2018 IPR025488 Protein of unknown function DUF4380 TL08_07490 e7d7f4e5bd7991a4ef9e66f73a0bcb50 176 Pfam PF01047 MarR family 62 114 5.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07490 e7d7f4e5bd7991a4ef9e66f73a0bcb50 176 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TL08_07490 e7d7f4e5bd7991a4ef9e66f73a0bcb50 176 SUPERFAMILY SSF46785 31 165 1.63E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_07490 e7d7f4e5bd7991a4ef9e66f73a0bcb50 176 Gene3D G3DSA:1.10.10.10 24 169 1.3E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07490 e7d7f4e5bd7991a4ef9e66f73a0bcb50 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 139 159 7.7E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07490 e7d7f4e5bd7991a4ef9e66f73a0bcb50 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 7.7E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07490 e7d7f4e5bd7991a4ef9e66f73a0bcb50 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 7.7E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_07490 e7d7f4e5bd7991a4ef9e66f73a0bcb50 176 SMART SM00347 48 149 3.5E-24 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 Gene3D G3DSA:3.40.50.720 25 290 7.7E-80 T 12-10-2018 TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 214 1.5E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 252 272 1.5E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 46 63 1.5E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 131 1.5E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 185 1.5E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 233 1.5E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 SUPERFAMILY SSF51735 44 288 2.88E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 51 288 1.7E-63 T 12-10-2018 TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 195 214 7.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 131 7.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_23660 349423dcfb08e85eaa335251d4d530ef 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 175 183 7.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_11205 e5fd6ced40130758b8576589881fa9f8 301 SUPERFAMILY SSF52317 3 193 2.65E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_11205 e5fd6ced40130758b8576589881fa9f8 301 Pfam PF01965 DJ-1/PfpI family 3 172 3.2E-19 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TL08_11205 e5fd6ced40130758b8576589881fa9f8 301 SUPERFAMILY SSF46689 212 262 1.39E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_11205 e5fd6ced40130758b8576589881fa9f8 301 Gene3D G3DSA:1.10.10.60 213 300 1.1E-15 T 12-10-2018 TL08_11205 e5fd6ced40130758b8576589881fa9f8 301 Pfam PF12833 Helix-turn-helix domain 234 296 1.0E-10 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_11205 e5fd6ced40130758b8576589881fa9f8 301 Gene3D G3DSA:3.40.50.880 1 212 4.7E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_11205 e5fd6ced40130758b8576589881fa9f8 301 SMART SM00342 228 300 0.0012 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_02620 3a195bdb0b870499dd638e4f928d765f 475 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 72 475 1.7E-163 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02620 3a195bdb0b870499dd638e4f928d765f 475 SUPERFAMILY SSF56762 82 475 2.88E-114 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02620 3a195bdb0b870499dd638e4f928d765f 475 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 109 120 - T 12-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02620 3a195bdb0b870499dd638e4f928d765f 475 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 60 475 46.153 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02620 3a195bdb0b870499dd638e4f928d765f 475 Gene3D G3DSA:1.10.645.20 71 475 6.3E-157 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02620 3a195bdb0b870499dd638e4f928d765f 475 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 187 475 4.1E-105 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_07345 375f54d8a1b21c33ee41f828615a8f0c 172 SUPERFAMILY SSF88946 4 95 5.49E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_07345 375f54d8a1b21c33ee41f828615a8f0c 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 159 6.0E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_07345 375f54d8a1b21c33ee41f828615a8f0c 172 SUPERFAMILY SSF88659 100 159 6.73E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_07345 375f54d8a1b21c33ee41f828615a8f0c 172 Gene3D G3DSA:1.10.1740.10 1 78 3.9E-6 T 12-10-2018 TL08_07345 375f54d8a1b21c33ee41f828615a8f0c 172 Pfam PF08281 Sigma-70, region 4 102 153 1.7E-17 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_07345 375f54d8a1b21c33ee41f828615a8f0c 172 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 162 1.7E-47 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 TL08_07345 375f54d8a1b21c33ee41f828615a8f0c 172 Gene3D G3DSA:1.10.10.10 79 161 3.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07345 375f54d8a1b21c33ee41f828615a8f0c 172 Pfam PF04542 Sigma-70 region 2 18 77 4.5E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 Gene3D G3DSA:3.40.50.300 104 282 9.3E-68 T 12-10-2018 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 Gene3D G3DSA:3.40.50.10050 405 512 1.1E-31 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 SUPERFAMILY SSF52156 391 518 6.41E-34 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 ProSitePatterns PS01176 Initiation factor 2 signature. 563 585 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 SUPERFAMILY SSF50447 284 367 1.23E-22 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 Gene3D G3DSA:2.40.30.10 283 401 2.1E-38 T 12-10-2018 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 2 610 15.842 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 27 72 7.0E-6 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 Pfam PF11987 Translation-initiation factor 2 398 501 6.0E-31 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 PRINTS PR00315 GTP-binding elongation factor signature 110 123 4.5E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 PRINTS PR00315 GTP-binding elongation factor signature 214 223 4.5E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 PRINTS PR00315 GTP-binding elongation factor signature 178 189 4.5E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 PRINTS PR00315 GTP-binding elongation factor signature 162 172 4.5E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 Pfam PF00009 Elongation factor Tu GTP binding domain 111 271 3.5E-34 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 109 268 1.2E-32 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 Gene3D G3DSA:2.40.30.10 513 611 5.8E-30 T 12-10-2018 TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 SUPERFAMILY SSF52540 106 273 5.31E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 SUPERFAMILY SSF50447 513 610 1.1E-28 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_09180 ebacce659e2014ca8d7a0b6ffc0f64e9 611 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 19 611 1.8E-224 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TL08_12880 c61ce8226d42218dad9cc1d6467b97b4 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 327 1.2E-43 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_19550 aa3072ca8ff8b1ca972f66cdc3ab85d7 298 Pfam PF00535 Glycosyl transferase family 2 8 109 8.4E-17 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_19550 aa3072ca8ff8b1ca972f66cdc3ab85d7 298 SUPERFAMILY SSF53448 5 233 9.64E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_19550 aa3072ca8ff8b1ca972f66cdc3ab85d7 298 Gene3D G3DSA:3.90.550.10 3 217 7.6E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_12165 14e03d9c411c38148d9e12f127a9db55 870 Pfam PF02687 FtsX-like permease family 777 860 1.4E-5 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TL08_00910 34f923e6e8d0f9a860b28f5a61c06237 300 Gene3D G3DSA:1.10.3720.10 88 295 8.7E-18 T 12-10-2018 IPR035906 MetI-like superfamily TL08_00910 34f923e6e8d0f9a860b28f5a61c06237 300 SUPERFAMILY SSF161098 92 281 3.92E-24 T 12-10-2018 IPR035906 MetI-like superfamily TL08_00910 34f923e6e8d0f9a860b28f5a61c06237 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 291 6.5E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_04130 2faedea9756ab507b930b0970c36db88 479 Gene3D G3DSA:3.20.20.70 4 476 1.0E-136 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_04130 2faedea9756ab507b930b0970c36db88 479 SUPERFAMILY SSF54631 99 203 1.39E-14 T 12-10-2018 TL08_04130 2faedea9756ab507b930b0970c36db88 479 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 477 4.6E-244 T 12-10-2018 IPR005991 IMP dehydrogenase-related 1 TL08_04130 2faedea9756ab507b930b0970c36db88 479 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 474 3.1E-104 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TL08_04130 2faedea9756ab507b930b0970c36db88 479 SUPERFAMILY SSF51412 11 474 3.66E-91 T 12-10-2018 TL08_04130 2faedea9756ab507b930b0970c36db88 479 SMART SM01240 11 475 3.1E-191 T 12-10-2018 TL08_04130 2faedea9756ab507b930b0970c36db88 479 PIRSF PIRSF000130 3 479 3.0E-141 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 Gene3D G3DSA:3.40.50.300 545 802 2.0E-87 T 12-10-2018 TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 320 444 1.6E-15 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 584 714 3.4E-40 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 SMART SM00382 580 717 1.8E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 SMART SM00382 316 446 8.0E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 39 117 1.4E-12 T 12-10-2018 IPR003338 CDC48, N-terminal subdomain TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 SMART SM01072 135 219 0.0022 T 12-10-2018 IPR004201 CDC48, domain 2 TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 Gene3D G3DSA:1.10.8.60 716 788 2.0E-87 T 12-10-2018 TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 SUPERFAMILY SSF50692 41 116 1.86E-9 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 Gene3D G3DSA:2.40.40.20 29 118 6.4E-7 T 12-10-2018 TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 Gene3D G3DSA:3.40.50.300 276 449 6.5E-24 T 12-10-2018 TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 Gene3D G3DSA:1.10.8.60 450 541 1.8E-14 T 12-10-2018 TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 SUPERFAMILY SSF52540 545 801 7.48E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 SMART SM01073 30 118 2.0E-12 T 12-10-2018 IPR003338 CDC48, N-terminal subdomain TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 SUPERFAMILY SSF52540 280 530 6.35E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25435 d9e66f2d96715f97b9e18dcc40871f36 808 ProSitePatterns PS00674 AAA-protein family signature. 685 703 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TL08_05860 ebdf13f4d0130287cebdb3320ec96796 448 Pfam PF00202 Aminotransferase class-III 175 364 4.1E-21 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_05860 ebdf13f4d0130287cebdb3320ec96796 448 Pfam PF00202 Aminotransferase class-III 34 143 3.4E-17 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_05860 ebdf13f4d0130287cebdb3320ec96796 448 Gene3D G3DSA:3.90.1150.10 29 381 1.3E-80 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_05860 ebdf13f4d0130287cebdb3320ec96796 448 SUPERFAMILY SSF53383 13 382 5.39E-76 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_05860 ebdf13f4d0130287cebdb3320ec96796 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 214 250 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_05860 ebdf13f4d0130287cebdb3320ec96796 448 Gene3D G3DSA:3.40.640.10 68 293 1.3E-80 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_03250 cce85755c53bd7551876da77867d8061 152 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 12-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site TL08_03250 cce85755c53bd7551876da77867d8061 152 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 130 8.3E-30 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TL08_03250 cce85755c53bd7551876da77867d8061 152 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 129 20.951 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TL08_03250 cce85755c53bd7551876da77867d8061 152 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 127 2.4E-38 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L TL08_03250 cce85755c53bd7551876da77867d8061 152 Gene3D G3DSA:1.10.1200.120 1 131 1.1E-39 T 12-10-2018 IPR036019 Gated mechanosensitive channel TL08_03250 cce85755c53bd7551876da77867d8061 152 SUPERFAMILY SSF81330 10 124 9.81E-27 T 12-10-2018 IPR036019 Gated mechanosensitive channel TL08_03250 cce85755c53bd7551876da77867d8061 152 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 5.4E-9 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TL08_03250 cce85755c53bd7551876da77867d8061 152 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 80 88 5.4E-9 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TL08_03250 cce85755c53bd7551876da77867d8061 152 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 90 99 5.4E-9 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TL08_15860 307e42d3b35660191474c398734cfbdf 408 Gene3D G3DSA:1.10.630.10 12 408 1.1E-109 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 PRINTS PR00359 B-class P450 signature 156 171 1.8E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 PRINTS PR00359 B-class P450 signature 299 326 1.8E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 PRINTS PR00359 B-class P450 signature 357 368 1.8E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 PRINTS PR00359 B-class P450 signature 92 103 1.8E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 PRINTS PR00359 B-class P450 signature 327 342 1.8E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 PRINTS PR00359 B-class P450 signature 139 155 1.8E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 PRINTS PR00359 B-class P450 signature 281 292 1.8E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 PRINTS PR00359 B-class P450 signature 348 357 1.8E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 PRINTS PR00359 B-class P450 signature 200 222 1.8E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 Pfam PF00067 Cytochrome P450 48 377 1.3E-24 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_15860 307e42d3b35660191474c398734cfbdf 408 SUPERFAMILY SSF48264 15 408 6.16E-84 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Pfam PF08326 Acetyl-CoA carboxylase, central region 1011 1198 4.3E-13 T 12-10-2018 IPR013537 Acetyl-CoA carboxylase, central domain GO:0003989|GO:0005524|GO:0006633 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-163765|Reactome: R-HSA-196780|Reactome: R-HSA-200425|Reactome: R-HSA-2426168 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 115 2.0E-32 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Gene3D G3DSA:2.40.50.100 580 654 8.2E-16 T 12-10-2018 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Pfam PF01039 Carboxyl transferase domain 1322 1812 6.8E-33 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Pfam PF02785 Biotin carboxylase C-terminal domain 339 448 2.2E-35 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 SUPERFAMILY SSF52440 2 118 3.17E-32 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 SUPERFAMILY SSF52096 1504 1815 5.97E-37 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 SUPERFAMILY SSF51230 578 654 2.62E-16 T 12-10-2018 IPR011053 Single hybrid motif TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Gene3D G3DSA:3.30.470.130 1 452 1.4E-167 T 12-10-2018 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 SUPERFAMILY SSF52096 1251 1489 3.79E-24 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Pfam PF00364 Biotin-requiring enzyme 588 653 3.5E-10 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 SUPERFAMILY SSF56059 88 335 1.15E-57 T 12-10-2018 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 158 172 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 SUPERFAMILY SSF51246 334 449 1.15E-35 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Gene3D G3DSA:3.90.226.10 1248 1495 2.1E-37 T 12-10-2018 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Gene3D G3DSA:3.90.226.10 1504 1816 4.4E-57 T 12-10-2018 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 327 2.3E-62 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_18845 b815cd1ea706a4a2a9368f6ce1b5c0f5 1816 SMART SM00878 339 447 4.2E-51 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_17470 6131a54eac6ec6d132a683d6ccdcbea7 120 Gene3D G3DSA:2.60.200.60 29 117 5.3E-13 T 12-10-2018 TL08_17470 6131a54eac6ec6d132a683d6ccdcbea7 120 Pfam PF05488 PAAR motif 41 108 1.7E-12 T 12-10-2018 IPR008727 PAAR motif TL08_17470 6131a54eac6ec6d132a683d6ccdcbea7 120 Pfam PF05488 PAAR motif 85 119 3.5E-8 T 12-10-2018 IPR008727 PAAR motif TL08_24670 00e77e45e07d8d954399d6dddab26ea9 249 Pfam PF02585 GlcNAc-PI de-N-acetylase 16 146 5.0E-29 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TL08_24670 00e77e45e07d8d954399d6dddab26ea9 249 SUPERFAMILY SSF102588 13 224 2.88E-48 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_24670 00e77e45e07d8d954399d6dddab26ea9 249 Gene3D G3DSA:3.40.50.10320 3 247 2.1E-70 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 Hamap MF_00173 Arginine repressor [argR]. 1 167 59.308 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 Pfam PF01316 Arginine repressor, DNA binding domain 12 79 5.9E-22 T 12-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 SUPERFAMILY SSF46785 11 78 1.2E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 Gene3D G3DSA:1.10.10.10 1 83 1.3E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 PRINTS PR01467 Bacterial arginine repressor signature 46 61 1.1E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 PRINTS PR01467 Bacterial arginine repressor signature 30 43 1.1E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 PRINTS PR01467 Bacterial arginine repressor signature 103 116 1.1E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 PRINTS PR01467 Bacterial arginine repressor signature 133 148 1.1E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 Gene3D G3DSA:3.30.1360.40 86 164 4.9E-30 T 12-10-2018 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 SUPERFAMILY SSF55252 95 162 4.45E-18 T 12-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 TIGRFAM TIGR01529 argR_whole: arginine repressor 14 163 1.7E-46 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 Pfam PF02863 Arginine repressor, C-terminal domain 95 161 1.0E-24 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 TL08_18100 e7a7802bf12c256e9206bf590dc510dd 195 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 103 160 1.0E-17 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 TL08_13720 8e53657536b46eea4da3bfb53082ac38 218 SUPERFAMILY SSF56214 101 212 5.58E-15 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_13720 8e53657536b46eea4da3bfb53082ac38 218 PRINTS PR01399 Enterobactin synthetase component D signature 37 57 4.2E-26 T 12-10-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 TL08_13720 8e53657536b46eea4da3bfb53082ac38 218 PRINTS PR01399 Enterobactin synthetase component D signature 144 160 4.2E-26 T 12-10-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 TL08_13720 8e53657536b46eea4da3bfb53082ac38 218 PRINTS PR01399 Enterobactin synthetase component D signature 67 85 4.2E-26 T 12-10-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 TL08_13720 8e53657536b46eea4da3bfb53082ac38 218 Gene3D G3DSA:3.90.470.20 21 114 4.6E-6 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_13720 8e53657536b46eea4da3bfb53082ac38 218 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 102 177 2.8E-10 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_18715 05d9d45849437e8c5708fe429de9ec1f 200 Gene3D G3DSA:1.10.10.60 4 54 1.5E-10 T 12-10-2018 TL08_18715 05d9d45849437e8c5708fe429de9ec1f 200 Gene3D G3DSA:1.10.357.10 56 188 7.5E-18 T 12-10-2018 TL08_18715 05d9d45849437e8c5708fe429de9ec1f 200 SUPERFAMILY SSF48498 78 188 4.67E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_18715 05d9d45849437e8c5708fe429de9ec1f 200 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 184 6.0E-12 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TL08_18715 05d9d45849437e8c5708fe429de9ec1f 200 SUPERFAMILY SSF46689 5 67 4.26E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18715 05d9d45849437e8c5708fe429de9ec1f 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 2.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 SUPERFAMILY SSF46894 147 217 4.76E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 3.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 3.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 3.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 SMART SM00448 6 118 2.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 Pfam PF00072 Response regulator receiver domain 8 118 5.8E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 Gene3D G3DSA:3.40.50.12740 6 217 2.5E-65 T 12-10-2018 TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 1.3E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 SUPERFAMILY SSF52172 4 131 1.85E-32 T 12-10-2018 IPR011006 CheY-like superfamily TL08_23940 9e4e24829c89377b8ae276a7d44d92b8 218 SMART SM00421 154 211 4.4E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_25115 11ba7951b352c1aa97b74a78224aa6f8 412 SUPERFAMILY SSF51338 8 393 5.07E-24 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_25115 11ba7951b352c1aa97b74a78224aa6f8 412 Gene3D G3DSA:3.20.20.140 66 355 2.0E-128 T 12-10-2018 TL08_25115 11ba7951b352c1aa97b74a78224aa6f8 412 SUPERFAMILY SSF51556 65 359 2.84E-46 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_25115 11ba7951b352c1aa97b74a78224aa6f8 412 Gene3D G3DSA:2.30.40.10 16 389 2.0E-128 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_25115 11ba7951b352c1aa97b74a78224aa6f8 412 Pfam PF01979 Amidohydrolase family 253 390 2.1E-12 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_23485 5a7047622dd2c6795f3b437fa8b7e172 360 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 61 360 4.1E-114 T 12-10-2018 IPR013459 Rhamnose ABC transporter, substrate-binding protein RhaS GO:0015762 TL08_23485 5a7047622dd2c6795f3b437fa8b7e172 360 SUPERFAMILY SSF53822 59 360 6.64E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_23485 5a7047622dd2c6795f3b437fa8b7e172 360 Pfam PF13407 Periplasmic binding protein domain 61 317 1.6E-54 T 12-10-2018 IPR025997 Periplasmic binding protein TL08_23485 5a7047622dd2c6795f3b437fa8b7e172 360 Gene3D G3DSA:3.40.50.2300 161 360 2.2E-119 T 12-10-2018 TL08_23485 5a7047622dd2c6795f3b437fa8b7e172 360 Gene3D G3DSA:3.40.50.2300 61 344 2.2E-119 T 12-10-2018 TL08_01425 dfb34b7015876c1bb70fd2355126692e 424 SUPERFAMILY SSF56601 75 419 1.14E-86 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_01425 dfb34b7015876c1bb70fd2355126692e 424 Gene3D G3DSA:3.40.710.10 40 407 3.0E-89 T 12-10-2018 TL08_01425 dfb34b7015876c1bb70fd2355126692e 424 Pfam PF00144 Beta-lactamase 78 409 5.8E-71 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_02035 69d402c11b96a58b64d1a15713fe43e8 220 Gene3D G3DSA:3.30.70.2390 121 210 9.6E-30 T 12-10-2018 TL08_02035 69d402c11b96a58b64d1a15713fe43e8 220 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 123 212 7.8E-10 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain TL08_02900 284a50ed8560efafdd82c01eb7d8cec2 127 SUPERFAMILY SSF54736 55 127 1.92E-20 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TL08_02900 284a50ed8560efafdd82c01eb7d8cec2 127 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 127 1.8E-45 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02900 284a50ed8560efafdd82c01eb7d8cec2 127 Gene3D G3DSA:1.20.5.710 4 56 1.4E-14 T 12-10-2018 TL08_02900 284a50ed8560efafdd82c01eb7d8cec2 127 Gene3D G3DSA:3.30.1390.10 57 127 8.2E-27 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TL08_02900 284a50ed8560efafdd82c01eb7d8cec2 127 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 7 51 9.8E-16 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02900 284a50ed8560efafdd82c01eb7d8cec2 127 SUPERFAMILY SSF48300 5 62 9.68E-13 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02900 284a50ed8560efafdd82c01eb7d8cec2 127 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 127 2.0E-25 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02900 284a50ed8560efafdd82c01eb7d8cec2 127 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 98 1.0E-11 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02900 284a50ed8560efafdd82c01eb7d8cec2 127 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 127 22.974 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_01730 40251491f4979ca1c05f03852308c968 528 SUPERFAMILY SSF50249 41 180 1.49E-33 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_01730 40251491f4979ca1c05f03852308c968 528 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 47 528 35.998 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_01730 40251491f4979ca1c05f03852308c968 528 Gene3D G3DSA:2.40.50.140 42 180 1.5E-36 T 12-10-2018 TL08_01730 40251491f4979ca1c05f03852308c968 528 PRINTS PR00982 Lysyl-tRNA synthetase signature 224 234 1.1E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_01730 40251491f4979ca1c05f03852308c968 528 PRINTS PR00982 Lysyl-tRNA synthetase signature 411 427 1.1E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_01730 40251491f4979ca1c05f03852308c968 528 PRINTS PR00982 Lysyl-tRNA synthetase signature 287 304 1.1E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_01730 40251491f4979ca1c05f03852308c968 528 PRINTS PR00982 Lysyl-tRNA synthetase signature 269 282 1.1E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_01730 40251491f4979ca1c05f03852308c968 528 PRINTS PR00982 Lysyl-tRNA synthetase signature 240 256 1.1E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_01730 40251491f4979ca1c05f03852308c968 528 Gene3D G3DSA:3.30.930.10 186 528 8.2E-114 T 12-10-2018 TL08_01730 40251491f4979ca1c05f03852308c968 528 Pfam PF01336 OB-fold nucleic acid binding domain 95 171 6.2E-9 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TL08_01730 40251491f4979ca1c05f03852308c968 528 Pfam PF00152 tRNA synthetases class II (D, K and N) 187 525 1.2E-71 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_01730 40251491f4979ca1c05f03852308c968 528 SUPERFAMILY SSF55681 187 526 2.99E-103 T 12-10-2018 TL08_01730 40251491f4979ca1c05f03852308c968 528 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 43 527 3.6E-143 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_16235 dfc76b71d29ee67a646b0f06ad4a092b 489 Pfam PF07690 Major Facilitator Superfamily 25 417 2.1E-42 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_16235 dfc76b71d29ee67a646b0f06ad4a092b 489 SUPERFAMILY SSF103473 18 469 2.22E-57 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_16235 dfc76b71d29ee67a646b0f06ad4a092b 489 Gene3D G3DSA:1.20.1250.20 205 442 4.9E-16 T 12-10-2018 TL08_16235 dfc76b71d29ee67a646b0f06ad4a092b 489 Gene3D G3DSA:1.20.1250.20 17 204 1.0E-38 T 12-10-2018 TL08_12535 645b80131ffc3fc2759e15c3dc5bc229 124 Gene3D G3DSA:1.20.120.910 5 124 1.8E-24 T 12-10-2018 TL08_12535 645b80131ffc3fc2759e15c3dc5bc229 124 SUPERFAMILY SSF57716 91 122 9.52E-8 T 12-10-2018 TL08_12535 645b80131ffc3fc2759e15c3dc5bc229 124 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 89 122 1.0E-8 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 TL08_20455 39ba3e7ee67017ae8e45f6ac5454b9e3 357 Pfam PF03969 AFG1-like ATPase 36 221 1.3E-38 T 12-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 TL08_20455 39ba3e7ee67017ae8e45f6ac5454b9e3 357 Pfam PF03969 AFG1-like ATPase 223 335 8.6E-17 T 12-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 TL08_20455 39ba3e7ee67017ae8e45f6ac5454b9e3 357 SUPERFAMILY SSF52540 82 204 2.77E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20455 39ba3e7ee67017ae8e45f6ac5454b9e3 357 Gene3D G3DSA:3.40.50.300 15 203 1.5E-14 T 12-10-2018 TL08_09655 626845fd187b4b9623c6c7502e23dd73 306 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 137 304 2.4E-56 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TL08_09655 626845fd187b4b9623c6c7502e23dd73 306 PIRSF PIRSF006250 28 306 2.1E-92 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 TL08_09655 626845fd187b4b9623c6c7502e23dd73 306 Gene3D G3DSA:3.90.1170.20 39 303 7.8E-100 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TL08_09655 626845fd187b4b9623c6c7502e23dd73 306 SUPERFAMILY SSF51690 137 305 5.89E-55 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TL08_09655 626845fd187b4b9623c6c7502e23dd73 306 SUPERFAMILY SSF54675 28 136 7.06E-28 T 12-10-2018 TL08_09655 626845fd187b4b9623c6c7502e23dd73 306 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 47 135 1.0E-21 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TL08_09655 626845fd187b4b9623c6c7502e23dd73 306 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 35 304 8.3E-88 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 TL08_09655 626845fd187b4b9623c6c7502e23dd73 306 Gene3D G3DSA:3.20.20.70 141 296 7.8E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_08860 654537e6192321704973171a880b79a6 294 SUPERFAMILY SSF88659 140 217 1.44E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_08860 654537e6192321704973171a880b79a6 294 SUPERFAMILY SSF88946 40 139 8.9E-28 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 SUPERFAMILY SSF88659 206 291 2.43E-22 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_08860 654537e6192321704973171a880b79a6 294 Pfam PF04542 Sigma-70 region 2 67 139 5.0E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 PIRSF PIRSF000770 25 49 110.0 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 PIRSF PIRSF000770 41 294 3.8E-54 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 259 285 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 Gene3D G3DSA:1.20.140.160 138 292 1.3E-45 T 12-10-2018 TL08_08860 654537e6192321704973171a880b79a6 294 PRINTS PR00046 Major sigma-70 factor signature 259 274 8.3E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 PRINTS PR00046 Major sigma-70 factor signature 242 254 8.3E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 PRINTS PR00046 Major sigma-70 factor signature 94 107 8.3E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 PRINTS PR00046 Major sigma-70 factor signature 274 285 8.3E-13 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 Pfam PF04545 Sigma-70, region 4 238 286 6.1E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 94 107 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 64 289 1.0E-34 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_08860 654537e6192321704973171a880b79a6 294 Gene3D G3DSA:1.10.1740.10 53 136 3.1E-30 T 12-10-2018 TL08_08860 654537e6192321704973171a880b79a6 294 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 67 289 8.6E-83 T 12-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TL08_24300 5909f59bc12e07af1c5228b3d9791fe3 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TL08_24300 5909f59bc12e07af1c5228b3d9791fe3 477 Gene3D G3DSA:3.40.309.10 261 450 1.5E-173 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_24300 5909f59bc12e07af1c5228b3d9791fe3 477 Gene3D G3DSA:3.40.605.10 26 476 1.5E-173 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_24300 5909f59bc12e07af1c5228b3d9791fe3 477 SUPERFAMILY SSF53720 16 476 1.7E-161 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_24300 5909f59bc12e07af1c5228b3d9791fe3 477 Pfam PF00171 Aldehyde dehydrogenase family 32 476 7.7E-164 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_16575 077fc37d797581276580ceb13626b724 379 Gene3D G3DSA:3.40.50.1820 1 378 4.9E-113 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16575 077fc37d797581276580ceb13626b724 379 PIRSF PIRSF001112 1 379 1.6E-97 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 TL08_16575 077fc37d797581276580ceb13626b724 379 Pfam PF06441 Epoxide hydrolase N terminus 2 113 2.5E-29 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 TL08_16575 077fc37d797581276580ceb13626b724 379 PRINTS PR00412 Epoxide hydrolase signature 133 148 5.0E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16575 077fc37d797581276580ceb13626b724 379 PRINTS PR00412 Epoxide hydrolase signature 193 206 5.0E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16575 077fc37d797581276580ceb13626b724 379 PRINTS PR00412 Epoxide hydrolase signature 351 373 5.0E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16575 077fc37d797581276580ceb13626b724 379 PRINTS PR00412 Epoxide hydrolase signature 104 122 5.0E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16575 077fc37d797581276580ceb13626b724 379 SUPERFAMILY SSF53474 2 375 6.89E-80 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_03680 37b622630a2615b5b52398c0f6c8caef 282 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 202 212 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 TL08_03680 37b622630a2615b5b52398c0f6c8caef 282 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 109 122 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 TL08_03680 37b622630a2615b5b52398c0f6c8caef 282 SUPERFAMILY SSF53178 97 280 2.22E-65 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TL08_03680 37b622630a2615b5b52398c0f6c8caef 282 Gene3D G3DSA:3.40.50.1470 83 282 3.6E-70 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TL08_03680 37b622630a2615b5b52398c0f6c8caef 282 Pfam PF01195 Peptidyl-tRNA hydrolase 98 280 8.8E-56 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TL08_03680 37b622630a2615b5b52398c0f6c8caef 282 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 7.2E-12 T 12-10-2018 IPR019933 DivIVA domain TL08_03680 37b622630a2615b5b52398c0f6c8caef 282 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 45 81 1.2E-9 T 12-10-2018 IPR019933 DivIVA domain TL08_03680 37b622630a2615b5b52398c0f6c8caef 282 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 98 280 2.9E-57 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TL08_03680 37b622630a2615b5b52398c0f6c8caef 282 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 96 273 33.153 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 Gene3D G3DSA:2.60.40.10 469 547 3.9E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 Gene3D G3DSA:2.60.40.10 558 645 3.7E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 Pfam PF00089 Trypsin 244 386 2.4E-4 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 Gene3D G3DSA:2.40.10.10 225 297 1.7E-40 T 12-10-2018 TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 310 330 4.9E-5 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 242 256 4.9E-5 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 378 392 4.9E-5 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 331 348 4.9E-5 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 Gene3D G3DSA:2.40.10.10 298 388 1.7E-40 T 12-10-2018 TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 363 374 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 SUPERFAMILY SSF50494 225 387 1.0E-19 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_01775 d271d24800c8b6de8e21cbc7f5480174 719 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 677 708 0.0022 T 12-10-2018 TL08_26670 0c24ed2b1a597b71107f1790bd8f21a1 286 SUPERFAMILY SSF69318 32 218 8.76E-8 T 12-10-2018 TL08_02990 2b73410d068a2ded9284bb9cddbca3ea 236 Pfam PF00573 Ribosomal protein L4/L1 family 18 204 9.2E-64 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TL08_02990 2b73410d068a2ded9284bb9cddbca3ea 236 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 204 2.2E-69 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02990 2b73410d068a2ded9284bb9cddbca3ea 236 Gene3D G3DSA:3.40.1370.10 3 211 6.4E-74 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TL08_02990 2b73410d068a2ded9284bb9cddbca3ea 236 SUPERFAMILY SSF52166 4 205 3.27E-73 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TL08_02990 2b73410d068a2ded9284bb9cddbca3ea 236 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 10 209 32.739 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_16040 c77948ea664702374b3050e0faaed0e0 491 SUPERFAMILY SSF49503 363 471 1.02E-28 T 12-10-2018 IPR008972 Cupredoxin TL08_16040 c77948ea664702374b3050e0faaed0e0 491 ProSitePatterns PS00080 Multicopper oxidases signature 2. 454 465 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 TL08_16040 c77948ea664702374b3050e0faaed0e0 491 Gene3D G3DSA:2.60.40.420 15 164 9.2E-49 T 12-10-2018 IPR008972 Cupredoxin TL08_16040 c77948ea664702374b3050e0faaed0e0 491 SUPERFAMILY SSF49503 31 169 2.29E-38 T 12-10-2018 IPR008972 Cupredoxin TL08_16040 c77948ea664702374b3050e0faaed0e0 491 Gene3D G3DSA:2.60.40.420 350 477 2.6E-38 T 12-10-2018 IPR008972 Cupredoxin TL08_16040 c77948ea664702374b3050e0faaed0e0 491 SUPERFAMILY SSF49503 174 309 1.92E-24 T 12-10-2018 IPR008972 Cupredoxin TL08_16040 c77948ea664702374b3050e0faaed0e0 491 Pfam PF07731 Multicopper oxidase 359 471 8.2E-22 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 TL08_16040 c77948ea664702374b3050e0faaed0e0 491 Pfam PF07732 Multicopper oxidase 58 168 1.8E-32 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TL08_16040 c77948ea664702374b3050e0faaed0e0 491 Gene3D G3DSA:2.60.40.420 166 346 1.0E-43 T 12-10-2018 IPR008972 Cupredoxin TL08_16920 832dfed1fd14003bb0acdb5d93cbbd42 393 SUPERFAMILY SSF53383 41 353 4.44E-27 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_16920 832dfed1fd14003bb0acdb5d93cbbd42 393 Gene3D G3DSA:3.40.640.10 37 292 1.6E-49 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 193 5.0E-69 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 Gene3D G3DSA:3.30.300.10 402 522 2.9E-52 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 Pfam PF00958 GMP synthase C terminal domain 429 521 6.2E-38 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 4.9E-6 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 4.9E-6 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 4.9E-6 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 522 6.7E-146 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 SUPERFAMILY SSF52402 183 442 6.62E-57 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 SUPERFAMILY SSF54810 401 522 9.68E-47 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 217 320 3.0E-5 T 12-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 Gene3D G3DSA:3.40.50.880 6 199 1.1E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 Gene3D G3DSA:3.40.50.620 200 401 2.9E-72 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 Pfam PF00117 Glutamine amidotransferase class-I 11 189 3.9E-38 T 12-10-2018 IPR017926 Glutamine amidotransferase TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 2.6E-8 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 2.6E-8 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 2.6E-8 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 SUPERFAMILY SSF52317 6 227 4.3E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 522 53.066 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 PRINTS PR00097 Anthranilate synthase component II signature 80 91 5.1E-6 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 PRINTS PR00097 Anthranilate synthase component II signature 53 62 5.1E-6 T 12-10-2018 TL08_24740 538d2d0ffb1b386064a442b320b01d1c 522 PRINTS PR00097 Anthranilate synthase component II signature 167 180 5.1E-6 T 12-10-2018 TL08_23215 ab7b9628398af11fe1a8486288acadc6 330 Pfam PF03193 RsgA GTPase 91 259 2.7E-40 T 12-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 TL08_23215 ab7b9628398af11fe1a8486288acadc6 330 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 66 319 2.1E-41 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 TL08_23215 ab7b9628398af11fe1a8486288acadc6 330 SUPERFAMILY SSF52540 109 320 1.38E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23215 ab7b9628398af11fe1a8486288acadc6 330 Gene3D G3DSA:3.40.50.300 94 259 3.0E-35 T 12-10-2018 TL08_07585 c22a323e75a1117acea52111d0d7ef3d 336 Gene3D G3DSA:3.40.50.2300 56 307 1.5E-42 T 12-10-2018 TL08_07585 c22a323e75a1117acea52111d0d7ef3d 336 SMART SM00354 1 71 2.6E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_07585 c22a323e75a1117acea52111d0d7ef3d 336 Gene3D G3DSA:3.40.50.2300 160 291 1.5E-42 T 12-10-2018 TL08_07585 c22a323e75a1117acea52111d0d7ef3d 336 SUPERFAMILY SSF47413 2 60 5.63E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_07585 c22a323e75a1117acea52111d0d7ef3d 336 Gene3D G3DSA:1.10.260.40 1 55 1.4E-19 T 12-10-2018 TL08_07585 c22a323e75a1117acea52111d0d7ef3d 336 SUPERFAMILY SSF53822 58 324 3.21E-38 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_07585 c22a323e75a1117acea52111d0d7ef3d 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 5.7E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_07585 c22a323e75a1117acea52111d0d7ef3d 336 Pfam PF13377 Periplasmic binding protein-like domain 168 330 6.1E-31 T 12-10-2018 TL08_10665 fc0b1c7ffc3b4d3095c0e91016cc6573 514 SUPERFAMILY SSF49503 55 204 3.76E-24 T 12-10-2018 IPR008972 Cupredoxin TL08_10665 fc0b1c7ffc3b4d3095c0e91016cc6573 514 Pfam PF07732 Multicopper oxidase 76 204 5.2E-16 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TL08_10665 fc0b1c7ffc3b4d3095c0e91016cc6573 514 Gene3D G3DSA:2.60.40.420 116 202 2.4E-23 T 12-10-2018 IPR008972 Cupredoxin TL08_10665 fc0b1c7ffc3b4d3095c0e91016cc6573 514 Gene3D G3DSA:2.60.40.420 36 115 2.5E-18 T 12-10-2018 IPR008972 Cupredoxin TL08_10665 fc0b1c7ffc3b4d3095c0e91016cc6573 514 Gene3D G3DSA:2.60.40.420 380 514 1.3E-41 T 12-10-2018 IPR008972 Cupredoxin TL08_10665 fc0b1c7ffc3b4d3095c0e91016cc6573 514 SUPERFAMILY SSF49503 209 341 6.97E-22 T 12-10-2018 IPR008972 Cupredoxin TL08_10665 fc0b1c7ffc3b4d3095c0e91016cc6573 514 SUPERFAMILY SSF49503 393 513 6.27E-26 T 12-10-2018 IPR008972 Cupredoxin TL08_10665 fc0b1c7ffc3b4d3095c0e91016cc6573 514 Gene3D G3DSA:2.60.40.420 203 379 6.4E-50 T 12-10-2018 IPR008972 Cupredoxin TL08_10665 fc0b1c7ffc3b4d3095c0e91016cc6573 514 Pfam PF07731 Multicopper oxidase 407 514 2.5E-20 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 TL08_13850 65be81b0635b359e44e65eeed71ed4ef 590 Pfam PF00005 ABC transporter 405 534 2.8E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13850 65be81b0635b359e44e65eeed71ed4ef 590 Pfam PF00005 ABC transporter 67 216 1.7E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13850 65be81b0635b359e44e65eeed71ed4ef 590 SUPERFAMILY SSF52540 400 588 2.82E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13850 65be81b0635b359e44e65eeed71ed4ef 590 SMART SM00382 412 588 1.7E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13850 65be81b0635b359e44e65eeed71ed4ef 590 SMART SM00382 75 260 1.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13850 65be81b0635b359e44e65eeed71ed4ef 590 SUPERFAMILY SSF52540 51 268 8.08E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13850 65be81b0635b359e44e65eeed71ed4ef 590 Gene3D G3DSA:3.40.50.300 389 587 1.9E-37 T 12-10-2018 TL08_13850 65be81b0635b359e44e65eeed71ed4ef 590 Gene3D G3DSA:3.40.50.300 47 312 1.5E-57 T 12-10-2018 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 Pfam PF02785 Biotin carboxylase C-terminal domain 349 458 1.7E-35 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 Pfam PF00364 Biotin-requiring enzyme 530 596 4.4E-16 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 337 1.2E-75 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 SUPERFAMILY SSF56059 97 337 1.1E-58 T 12-10-2018 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 SUPERFAMILY SSF51246 343 462 1.05E-36 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 553 570 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 300 307 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 SUPERFAMILY SSF51230 524 596 8.09E-19 T 12-10-2018 IPR011053 Single hybrid motif TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 Pfam PF00289 Biotin carboxylase, N-terminal domain 16 124 1.6E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 SMART SM00878 349 458 2.0E-57 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 SUPERFAMILY SSF52440 13 127 2.3E-46 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 Gene3D G3DSA:2.40.50.100 525 598 9.2E-19 T 12-10-2018 TL08_23745 6fb5f89b9eaeedd4e2470726ba1b1a55 598 Gene3D G3DSA:3.30.470.130 5 464 1.2E-176 T 12-10-2018 TL08_17960 8e95ad5b6ec6b77253f9530f364e9179 278 SUPERFAMILY SSF46785 102 177 4.9E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17960 8e95ad5b6ec6b77253f9530f364e9179 278 SUPERFAMILY SSF46785 182 255 2.25E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17960 8e95ad5b6ec6b77253f9530f364e9179 278 Pfam PF04079 Segregation and condensation complex subunit ScpB 106 264 1.0E-48 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TL08_17960 8e95ad5b6ec6b77253f9530f364e9179 278 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 104 265 7.5E-30 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TL08_17960 8e95ad5b6ec6b77253f9530f364e9179 278 Gene3D G3DSA:1.10.10.10 181 274 6.6E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17960 8e95ad5b6ec6b77253f9530f364e9179 278 PIRSF PIRSF019345 91 278 3.5E-54 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TL08_17960 8e95ad5b6ec6b77253f9530f364e9179 278 Gene3D G3DSA:1.10.10.10 90 180 3.1E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21830 4456bb1c6038a75d8c014cf96cb8aeac 357 Gene3D G3DSA:1.10.1610.10 16 343 1.5E-124 T 12-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TL08_21830 4456bb1c6038a75d8c014cf96cb8aeac 357 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 20 351 1.6E-126 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TL08_21830 4456bb1c6038a75d8c014cf96cb8aeac 357 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 18 353 36.259 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TL08_21830 4456bb1c6038a75d8c014cf96cb8aeac 357 SUPERFAMILY SSF52733 12 352 4.19E-112 T 12-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TL08_21830 4456bb1c6038a75d8c014cf96cb8aeac 357 Pfam PF02277 Phosphoribosyltransferase 16 351 1.4E-134 T 12-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TL08_21830 4456bb1c6038a75d8c014cf96cb8aeac 357 Gene3D G3DSA:3.40.50.10210 63 334 1.5E-124 T 12-10-2018 TL08_12690 2a17280488f2765c13f2897ddd2143fb 359 SUPERFAMILY SSF53335 4 201 3.14E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_12690 2a17280488f2765c13f2897ddd2143fb 359 Gene3D G3DSA:3.40.50.150 2 235 2.3E-52 T 12-10-2018 TL08_12690 2a17280488f2765c13f2897ddd2143fb 359 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 8 201 2.5E-29 T 12-10-2018 TL08_08105 cfe16fe13774cffda216fc5ceb2f27fc 455 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 150 165 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TL08_08105 cfe16fe13774cffda216fc5ceb2f27fc 455 SUPERFAMILY SSF53623 12 306 6.0E-86 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_08105 cfe16fe13774cffda216fc5ceb2f27fc 455 Gene3D G3DSA:3.90.190.20 309 455 2.7E-32 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_08105 cfe16fe13774cffda216fc5ceb2f27fc 455 PIRSF PIRSF001563 5 454 8.6E-112 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TL08_08105 cfe16fe13774cffda216fc5ceb2f27fc 455 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 448 4.3E-95 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TL08_08105 cfe16fe13774cffda216fc5ceb2f27fc 455 SUPERFAMILY SSF53244 309 452 9.71E-24 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TL08_08105 cfe16fe13774cffda216fc5ceb2f27fc 455 Gene3D G3DSA:3.40.1190.10 7 308 5.4E-92 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TL08_08105 cfe16fe13774cffda216fc5ceb2f27fc 455 Pfam PF08245 Mur ligase middle domain 54 280 8.9E-11 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TL08_08105 cfe16fe13774cffda216fc5ceb2f27fc 455 Pfam PF02875 Mur ligase family, glutamate ligase domain 308 383 1.4E-8 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TL08_06200 297c4ede875d75e825f40f38bfd03b6a 174 Gene3D G3DSA:1.10.10.10 1 79 8.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06200 297c4ede875d75e825f40f38bfd03b6a 174 Gene3D G3DSA:1.20.1270.400 84 171 6.8E-24 T 12-10-2018 TL08_06200 297c4ede875d75e825f40f38bfd03b6a 174 SMART SM00418 2 89 0.0038 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_06200 297c4ede875d75e825f40f38bfd03b6a 174 Pfam PF12840 Helix-turn-helix domain 4 62 7.3E-15 T 12-10-2018 TL08_06200 297c4ede875d75e825f40f38bfd03b6a 174 SUPERFAMILY SSF46785 4 99 3.91E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 SUPERFAMILY SSF53223 2 121 1.63E-33 T 12-10-2018 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 Gene3D G3DSA:3.40.50.10860 8 276 1.6E-105 T 12-10-2018 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 281 7.2E-61 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 5.0E-65 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 5.0E-65 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 5.0E-65 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 5.0E-65 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 5.0E-65 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 5.0E-65 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 36.322 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 4.0E-32 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 SUPERFAMILY SSF51735 122 280 5.18E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24520 a0f16d4655f77d020c97446e39ad4ac6 285 Gene3D G3DSA:3.40.50.720 6 258 1.6E-105 T 12-10-2018 TL08_20190 17ec7b1b637bea1ac225a9dc05d8d6cb 225 Gene3D G3DSA:3.30.70.100 10 117 1.9E-17 T 12-10-2018 TL08_20190 17ec7b1b637bea1ac225a9dc05d8d6cb 225 Gene3D G3DSA:3.30.70.100 120 221 1.6E-15 T 12-10-2018 TL08_20190 17ec7b1b637bea1ac225a9dc05d8d6cb 225 SUPERFAMILY SSF54909 11 95 1.32E-5 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_20190 17ec7b1b637bea1ac225a9dc05d8d6cb 225 SUPERFAMILY SSF54909 135 205 1.29E-5 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_16675 8fa90691a8cfd67cd547728fcbfe5170 242 Gene3D G3DSA:2.40.10.10 109 240 3.1E-18 T 12-10-2018 TL08_16675 8fa90691a8cfd67cd547728fcbfe5170 242 SUPERFAMILY SSF50494 15 241 2.16E-42 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_16675 8fa90691a8cfd67cd547728fcbfe5170 242 Gene3D G3DSA:2.40.10.10 42 83 2.1E-11 T 12-10-2018 TL08_16675 8fa90691a8cfd67cd547728fcbfe5170 242 Pfam PF00089 Trypsin 42 236 1.6E-26 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_16675 8fa90691a8cfd67cd547728fcbfe5170 242 SMART SM00020 41 236 1.0E-25 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_16675 8fa90691a8cfd67cd547728fcbfe5170 242 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 67 82 1.8E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_16675 8fa90691a8cfd67cd547728fcbfe5170 242 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 111 125 1.8E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_16675 8fa90691a8cfd67cd547728fcbfe5170 242 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 187 199 1.8E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 SUPERFAMILY SSF53067 111 322 3.04E-35 T 12-10-2018 TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 SUPERFAMILY SSF53067 8 130 5.76E-27 T 12-10-2018 TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 Gene3D G3DSA:3.30.420.40 8 329 8.5E-114 T 12-10-2018 TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 8 327 2.5E-123 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 Pfam PF00814 Glycoprotease family 32 320 3.2E-96 T 12-10-2018 IPR000905 Gcp-like domain TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 9 22 1.7E-50 T 12-10-2018 IPR017861 Kae1/TsaD family TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 140 152 1.7E-50 T 12-10-2018 IPR017861 Kae1/TsaD family TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 164 185 1.7E-50 T 12-10-2018 IPR017861 Kae1/TsaD family TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 85 105 1.7E-50 T 12-10-2018 IPR017861 Kae1/TsaD family TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 106 125 1.7E-50 T 12-10-2018 IPR017861 Kae1/TsaD family TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 277 286 1.7E-50 T 12-10-2018 IPR017861 Kae1/TsaD family TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 9 320 3.8E-95 T 12-10-2018 IPR017861 Kae1/TsaD family TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 ProSitePatterns PS01016 Glycoprotease family signature. 105 125 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 6 346 60.816 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 TL08_24820 1b00c8455d3d9dd8aebbda62b59f22f8 352 Gene3D G3DSA:3.30.420.40 138 307 8.5E-114 T 12-10-2018 TL08_15715 34cf9953225ba453f3635e03025bdc35 246 Gene3D G3DSA:1.10.1660.10 7 199 8.6E-24 T 12-10-2018 TL08_15715 34cf9953225ba453f3635e03025bdc35 246 SMART SM00422 3 72 8.1E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_15715 34cf9953225ba453f3635e03025bdc35 246 Pfam PF13411 MerR HTH family regulatory protein 6 71 1.1E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_15715 34cf9953225ba453f3635e03025bdc35 246 SUPERFAMILY SSF46955 4 105 4.4E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_14760 880406cbd905b036331b03230f3aa9e1 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 328 2.5E-28 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 SUPERFAMILY SSF51905 1 338 2.21E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14760 880406cbd905b036331b03230f3aa9e1 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 283 6.8E-23 T 12-10-2018 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 6.8E-23 T 12-10-2018 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 6.8E-23 T 12-10-2018 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 6.8E-23 T 12-10-2018 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 6.8E-23 T 12-10-2018 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 Gene3D G3DSA:3.50.50.60 3 325 2.9E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14760 880406cbd905b036331b03230f3aa9e1 474 Gene3D G3DSA:1.10.10.1100 370 437 2.0E-13 T 12-10-2018 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 Pfam PF04324 BFD-like [2Fe-2S] binding domain 381 432 2.0E-7 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TL08_14760 880406cbd905b036331b03230f3aa9e1 474 Gene3D G3DSA:3.50.50.60 125 275 2.9E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14760 880406cbd905b036331b03230f3aa9e1 474 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 3.4E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 304 322 3.4E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 3.4E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_14760 880406cbd905b036331b03230f3aa9e1 474 PIRSF PIRSF037495 1 470 2.5E-118 T 12-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 TL08_04275 d529d42e0c35b34f38fde722717c5abb 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_04275 d529d42e0c35b34f38fde722717c5abb 212 SUPERFAMILY SSF48498 84 188 2.75E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_04275 d529d42e0c35b34f38fde722717c5abb 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 4.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_04275 d529d42e0c35b34f38fde722717c5abb 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 4.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_04275 d529d42e0c35b34f38fde722717c5abb 212 Gene3D G3DSA:1.10.357.10 1 197 4.0E-44 T 12-10-2018 TL08_04275 d529d42e0c35b34f38fde722717c5abb 212 SUPERFAMILY SSF46689 8 88 5.49E-21 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_04275 d529d42e0c35b34f38fde722717c5abb 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 2.1E-19 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06215 986c78b397dd52e38c0b7c6e5d8c9745 317 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 47 299 2.4E-60 T 12-10-2018 TL08_06215 986c78b397dd52e38c0b7c6e5d8c9745 317 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 13 262 1.3E-59 T 12-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 TL08_06215 986c78b397dd52e38c0b7c6e5d8c9745 317 SUPERFAMILY SSF53850 42 313 6.63E-44 T 12-10-2018 TL08_06215 986c78b397dd52e38c0b7c6e5d8c9745 317 Gene3D G3DSA:3.40.190.10 47 263 1.2E-56 T 12-10-2018 TL08_06215 986c78b397dd52e38c0b7c6e5d8c9745 317 Gene3D G3DSA:3.40.190.10 132 240 1.2E-56 T 12-10-2018 TL08_22065 9c13d62632d4d63699fdfdee3a7b32ed 81 Pfam PF10944 Protein of unknown function (DUF2630) 3 81 7.8E-28 T 12-10-2018 IPR020311 Uncharacterised protein family, Rv0898c TL08_22065 9c13d62632d4d63699fdfdee3a7b32ed 81 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 14 56 1.0E-6 T 12-10-2018 IPR020311 Uncharacterised protein family, Rv0898c TL08_08900 024b40fafb14620b99d292fe0d8e6205 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 366 2.0E-97 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 TL08_08900 024b40fafb14620b99d292fe0d8e6205 368 Pfam PF04055 Radical SAM superfamily 122 295 1.5E-24 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_08900 024b40fafb14620b99d292fe0d8e6205 368 Gene3D G3DSA:1.10.150.530 18 75 4.7E-8 T 12-10-2018 TL08_08900 024b40fafb14620b99d292fe0d8e6205 368 SUPERFAMILY SSF102114 115 339 1.12E-18 T 12-10-2018 TL08_08900 024b40fafb14620b99d292fe0d8e6205 368 Gene3D G3DSA:3.20.20.70 82 355 4.1E-95 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_08900 024b40fafb14620b99d292fe0d8e6205 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 368 66.733 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 TL08_08900 024b40fafb14620b99d292fe0d8e6205 368 PIRSF PIRSF006004 13 368 1.4E-119 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 TL08_04510 b35e63d1228f99b60e44ac39ee27d2ab 209 SUPERFAMILY SSF52218 8 201 2.88E-49 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_04510 b35e63d1228f99b60e44ac39ee27d2ab 209 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 7 199 8.7E-44 T 12-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 TL08_04510 b35e63d1228f99b60e44ac39ee27d2ab 209 Gene3D G3DSA:3.40.50.360 1 209 3.9E-63 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_04510 b35e63d1228f99b60e44ac39ee27d2ab 209 Pfam PF03358 NADPH-dependent FMN reductase 8 134 8.0E-17 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TL08_23585 f82684d9e31abe3aa69fc74ed9669c25 129 Pfam PF02575 YbaB/EbfC DNA-binding family 18 98 6.9E-6 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_19640 8ab507b9dabdd1a1674844b202d75643 375 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 199 342 5.8E-9 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 TL08_19640 8ab507b9dabdd1a1674844b202d75643 375 Gene3D G3DSA:3.40.50.2000 203 358 3.1E-72 T 12-10-2018 TL08_19640 8ab507b9dabdd1a1674844b202d75643 375 SUPERFAMILY SSF53756 1 370 3.49E-47 T 12-10-2018 TL08_19640 8ab507b9dabdd1a1674844b202d75643 375 Gene3D G3DSA:3.40.50.2000 1 367 3.1E-72 T 12-10-2018 TL08_07980 04f0d411d40c34252a9aef711a20c869 258 Gene3D G3DSA:3.40.190.10 39 255 4.4E-56 T 12-10-2018 TL08_07980 04f0d411d40c34252a9aef711a20c869 258 Gene3D G3DSA:3.40.190.10 116 218 4.4E-56 T 12-10-2018 TL08_07980 04f0d411d40c34252a9aef711a20c869 258 PIRSF PIRSF004846 4 258 1.7E-61 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TL08_07980 04f0d411d40c34252a9aef711a20c869 258 SUPERFAMILY SSF53850 37 258 4.58E-52 T 12-10-2018 TL08_07980 04f0d411d40c34252a9aef711a20c869 258 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 43 254 2.9E-36 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TL08_07980 04f0d411d40c34252a9aef711a20c869 258 Pfam PF13531 Bacterial extracellular solute-binding protein 38 256 6.9E-36 T 12-10-2018 TL08_17365 7381a5817b6e2b0bc0e80753d9061d51 286 SUPERFAMILY SSF51735 6 250 4.26E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_17365 7381a5817b6e2b0bc0e80753d9061d51 286 Gene3D G3DSA:3.40.50.720 7 286 1.3E-60 T 12-10-2018 TL08_17365 7381a5817b6e2b0bc0e80753d9061d51 286 Pfam PF13460 NAD(P)H-binding 11 179 1.7E-23 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_26405 ad760fdd19e9011bcda5e239f59ad574 106 SUPERFAMILY SSF50129 7 94 6.19E-20 T 12-10-2018 IPR011032 GroES-like superfamily TL08_26405 ad760fdd19e9011bcda5e239f59ad574 106 Pfam PF00166 Chaperonin 10 Kd subunit 8 93 1.2E-19 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_26405 ad760fdd19e9011bcda5e239f59ad574 106 PRINTS PR00297 10kDa chaperonin signature 60 72 1.2E-9 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_26405 ad760fdd19e9011bcda5e239f59ad574 106 PRINTS PR00297 10kDa chaperonin signature 81 94 1.2E-9 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_26405 ad760fdd19e9011bcda5e239f59ad574 106 PRINTS PR00297 10kDa chaperonin signature 34 55 1.2E-9 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_26405 ad760fdd19e9011bcda5e239f59ad574 106 PRINTS PR00297 10kDa chaperonin signature 8 23 1.2E-9 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_26405 ad760fdd19e9011bcda5e239f59ad574 106 SMART SM00883 7 94 4.3E-27 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TL08_26405 ad760fdd19e9011bcda5e239f59ad574 106 Gene3D G3DSA:2.30.33.40 4 96 1.9E-16 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 TL08_06310 2eebbba80c30af3f90042fd7c9e5bb87 350 Gene3D G3DSA:2.60.40.10 43 130 3.2E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_06310 2eebbba80c30af3f90042fd7c9e5bb87 350 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 153 347 7.5E-17 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal TL08_06310 2eebbba80c30af3f90042fd7c9e5bb87 350 SUPERFAMILY SSF49265 45 128 2.41E-5 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 TL08_06310 2eebbba80c30af3f90042fd7c9e5bb87 350 SUPERFAMILY SSF81296 153 349 7.84E-22 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_06310 2eebbba80c30af3f90042fd7c9e5bb87 350 Gene3D G3DSA:2.70.50.50 153 350 2.2E-23 T 12-10-2018 TL08_18885 d9793a2775e0544e7e5860d98bb0e6ad 945 Pfam PF01435 Peptidase family M48 130 334 2.2E-11 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TL08_18885 d9793a2775e0544e7e5860d98bb0e6ad 945 Gene3D G3DSA:3.30.2010.10 122 214 2.7E-8 T 12-10-2018 TL08_26730 07d83cf84c331c3aaab13bbd20b76d7c 295 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 249 1.4E-58 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_26730 07d83cf84c331c3aaab13bbd20b76d7c 295 SMART SM00079 32 250 0.0031 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 TL08_26730 07d83cf84c331c3aaab13bbd20b76d7c 295 Gene3D G3DSA:3.40.190.10 118 210 1.5E-62 T 12-10-2018 TL08_26730 07d83cf84c331c3aaab13bbd20b76d7c 295 SUPERFAMILY SSF53850 3 250 2.72E-61 T 12-10-2018 TL08_26730 07d83cf84c331c3aaab13bbd20b76d7c 295 SMART SM00062 32 251 7.0E-62 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_26730 07d83cf84c331c3aaab13bbd20b76d7c 295 Gene3D G3DSA:3.40.190.10 37 248 1.5E-62 T 12-10-2018 TL08_26730 07d83cf84c331c3aaab13bbd20b76d7c 295 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 54 67 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site TL08_16800 549b2323a19d06859776888f4b82d67d 363 SMART SM00382 73 228 1.7E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_16800 549b2323a19d06859776888f4b82d67d 363 Gene3D G3DSA:3.40.50.300 57 236 1.9E-23 T 12-10-2018 TL08_16800 549b2323a19d06859776888f4b82d67d 363 SUPERFAMILY SSF52540 52 296 4.26E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_16800 549b2323a19d06859776888f4b82d67d 363 Pfam PF07728 AAA domain (dynein-related subfamily) 77 218 1.1E-33 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TL08_09850 71326f5c536ae07f0617450e7768067b 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 1.8E-15 T 12-10-2018 TL08_09850 71326f5c536ae07f0617450e7768067b 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 5.2E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_09850 71326f5c536ae07f0617450e7768067b 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 5.2E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_09850 71326f5c536ae07f0617450e7768067b 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 5.2E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_09850 71326f5c536ae07f0617450e7768067b 160 SUPERFAMILY SSF54909 70 155 1.61E-10 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_09850 71326f5c536ae07f0617450e7768067b 160 Gene3D G3DSA:3.30.70.920 61 143 1.6E-15 T 12-10-2018 TL08_09850 71326f5c536ae07f0617450e7768067b 160 SUPERFAMILY SSF46785 6 66 2.09E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_09850 71326f5c536ae07f0617450e7768067b 160 Pfam PF01037 Lrp/AsnC ligand binding domain 75 146 4.9E-9 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TL08_09850 71326f5c536ae07f0617450e7768067b 160 SMART SM00344 7 116 6.4E-31 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TL08_09850 71326f5c536ae07f0617450e7768067b 160 Gene3D G3DSA:1.10.10.10 1 60 1.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23870 bf36a57582a27e3a3b55a13f3477b967 290 Gene3D G3DSA:1.10.357.140 14 163 1.6E-11 T 12-10-2018 TL08_23870 bf36a57582a27e3a3b55a13f3477b967 290 Pfam PF01040 UbiA prenyltransferase family 30 171 2.3E-17 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TL08_04635 56d4fd35ac8a061b07ea816522604729 406 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 404 47.143 T 12-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TL08_04635 56d4fd35ac8a061b07ea816522604729 406 SUPERFAMILY SSF53448 7 359 4.06E-70 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_04635 56d4fd35ac8a061b07ea816522604729 406 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 196 206 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TL08_04635 56d4fd35ac8a061b07ea816522604729 406 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 378 2.9E-139 T 12-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TL08_04635 56d4fd35ac8a061b07ea816522604729 406 SUPERFAMILY SSF51161 298 398 2.5E-18 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TL08_04635 56d4fd35ac8a061b07ea816522604729 406 Pfam PF00483 Nucleotidyl transferase 9 276 1.4E-70 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TL08_04635 56d4fd35ac8a061b07ea816522604729 406 Gene3D G3DSA:3.90.550.10 1 291 1.5E-82 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_04635 56d4fd35ac8a061b07ea816522604729 406 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TL08_04635 56d4fd35ac8a061b07ea816522604729 406 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TL08_04635 56d4fd35ac8a061b07ea816522604729 406 Gene3D G3DSA:2.160.10.10 292 405 3.1E-34 T 12-10-2018 TL08_04445 9cd137ebbe0dba4b9f8fcd5271dca289 374 SUPERFAMILY SSF52540 9 256 2.78E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04445 9cd137ebbe0dba4b9f8fcd5271dca289 374 Pfam PF00005 ABC transporter 30 186 3.6E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_04445 9cd137ebbe0dba4b9f8fcd5271dca289 374 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 302 1.6E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_04445 9cd137ebbe0dba4b9f8fcd5271dca289 374 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_04445 9cd137ebbe0dba4b9f8fcd5271dca289 374 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 321 2.2E-24 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_04445 9cd137ebbe0dba4b9f8fcd5271dca289 374 SMART SM00382 38 236 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_04445 9cd137ebbe0dba4b9f8fcd5271dca289 374 Gene3D G3DSA:3.40.50.300 7 339 1.3E-93 T 12-10-2018 TL08_23835 d62d1b935ef8067b9f4c2d5052a293bc 334 SUPERFAMILY SSF51658 8 318 1.96E-58 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_23835 d62d1b935ef8067b9f4c2d5052a293bc 334 Pfam PF01261 Xylose isomerase-like TIM barrel 22 274 2.3E-36 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_23835 d62d1b935ef8067b9f4c2d5052a293bc 334 Pfam PF07582 AP endonuclease family 2 C terminus 275 329 1.8E-23 T 12-10-2018 IPR011418 AP endonuclease, family 2, C-terminal TL08_23835 d62d1b935ef8067b9f4c2d5052a293bc 334 Gene3D G3DSA:3.20.20.150 2 323 2.1E-98 T 12-10-2018 TL08_23765 8e27b4d4bf00c9df22a8caa7dd2a2b96 360 Gene3D G3DSA:1.20.1260.20 16 176 2.4E-14 T 12-10-2018 IPR038332 PPE superfamily TL08_23765 8e27b4d4bf00c9df22a8caa7dd2a2b96 360 Pfam PF00823 PPE family 18 160 1.4E-10 T 12-10-2018 IPR000030 PPE family TL08_23765 8e27b4d4bf00c9df22a8caa7dd2a2b96 360 SUPERFAMILY SSF140459 15 174 5.23E-15 T 12-10-2018 TL08_23535 1634b72151ae125c4ca0531b3609410b 1082 SUPERFAMILY SSF88659 123 184 6.54E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_23535 1634b72151ae125c4ca0531b3609410b 1082 Pfam PF13490 Putative zinc-finger 198 232 5.9E-7 T 12-10-2018 IPR027383 Putative zinc-finger TL08_23535 1634b72151ae125c4ca0531b3609410b 1082 Gene3D G3DSA:1.10.1740.10 9 115 5.5E-14 T 12-10-2018 TL08_23535 1634b72151ae125c4ca0531b3609410b 1082 Pfam PF08281 Sigma-70, region 4 132 179 2.2E-6 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_23535 1634b72151ae125c4ca0531b3609410b 1082 Gene3D G3DSA:1.10.10.10 119 186 4.6E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23535 1634b72151ae125c4ca0531b3609410b 1082 Pfam PF04542 Sigma-70 region 2 31 99 7.4E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_23535 1634b72151ae125c4ca0531b3609410b 1082 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 184 5.2E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_23535 1634b72151ae125c4ca0531b3609410b 1082 SUPERFAMILY SSF88946 7 105 1.02E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_23535 1634b72151ae125c4ca0531b3609410b 1082 Gene3D G3DSA:1.10.10.1320 199 253 1.8E-5 T 12-10-2018 TL08_12115 69af111989172efd10b18303dd3e2fa4 988 Pfam PF00270 DEAD/DEAH box helicase 42 189 7.8E-18 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_12115 69af111989172efd10b18303dd3e2fa4 988 Pfam PF08148 DSHCT (NUC185) domain 816 983 1.7E-37 T 12-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal TL08_12115 69af111989172efd10b18303dd3e2fa4 988 SMART SM00487 36 218 2.8E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_12115 69af111989172efd10b18303dd3e2fa4 988 SMART SM01142 812 988 2.3E-63 T 12-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal TL08_12115 69af111989172efd10b18303dd3e2fa4 988 Gene3D G3DSA:3.40.50.300 214 473 5.1E-56 T 12-10-2018 TL08_12115 69af111989172efd10b18303dd3e2fa4 988 Pfam PF00271 Helicase conserved C-terminal domain 363 442 1.4E-4 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_12115 69af111989172efd10b18303dd3e2fa4 988 SUPERFAMILY SSF52540 50 456 7.41E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12115 69af111989172efd10b18303dd3e2fa4 988 Gene3D G3DSA:1.10.3380.30 810 966 1.7E-14 T 12-10-2018 TL08_12115 69af111989172efd10b18303dd3e2fa4 988 Gene3D G3DSA:3.40.50.300 20 213 5.6E-62 T 12-10-2018 TL08_12115 69af111989172efd10b18303dd3e2fa4 988 SMART SM00490 352 442 1.3E-13 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_24655 f2a1076cefcac0189ef4c710268eb441 216 Pfam PF09335 SNARE associated Golgi protein 41 163 6.2E-15 T 12-10-2018 IPR032816 SNARE associated Golgi protein TL08_02760 605bc6f3e35b8eea32cd844f48b6f7fe 549 SMART SM00332 41 379 9.0E-25 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_02760 605bc6f3e35b8eea32cd844f48b6f7fe 549 SMART SM00331 55 381 2.7E-17 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_02760 605bc6f3e35b8eea32cd844f48b6f7fe 549 SUPERFAMILY SSF81606 51 380 5.1E-56 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_02760 605bc6f3e35b8eea32cd844f48b6f7fe 549 Pfam PF13672 Protein phosphatase 2C 233 343 4.8E-6 T 12-10-2018 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 Pfam PF01820 D-ala D-ala ligase N-terminus 6 86 2.9E-13 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 Gene3D G3DSA:3.30.1490.20 112 185 2.7E-54 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 SUPERFAMILY SSF56059 97 308 1.15E-43 T 12-10-2018 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 64 75 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 Pfam PF07478 D-ala D-ala ligase C-terminus 107 309 8.2E-44 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 Gene3D G3DSA:3.40.50.20 2 85 2.1E-21 T 12-10-2018 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 PIRSF PIRSF039102 36 315 1.5E-62 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 PIRSF PIRSF039102 2 50 8.2E-6 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 SUPERFAMILY SSF52440 6 97 1.06E-20 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 312 27.484 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_27110 2f44a4bd08c99db1d5af1776b2f256a3 315 Gene3D G3DSA:3.30.470.20 87 308 2.7E-54 T 12-10-2018 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 Pfam PF06029 AlkA N-terminal domain 209 324 9.6E-28 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 SMART SM00342 110 193 1.5E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 Gene3D G3DSA:1.10.340.30 327 440 1.0E-26 T 12-10-2018 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 147 189 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 SMART SM00478 334 491 1.3E-19 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 Gene3D G3DSA:1.10.10.60 94 198 1.7E-15 T 12-10-2018 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 SUPERFAMILY SSF46689 147 196 1.43E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 SUPERFAMILY SSF55945 209 305 9.26E-24 T 12-10-2018 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 SMART SM01009 209 324 2.9E-41 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 Gene3D G3DSA:1.10.1670.10 442 494 5.3E-13 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 SUPERFAMILY SSF48150 315 488 4.71E-37 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 Gene3D G3DSA:3.30.310.20 209 324 2.0E-20 T 12-10-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 SUPERFAMILY SSF57884 12 94 9.94E-30 T 12-10-2018 IPR035451 Ada-like domain superfamily TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 Gene3D G3DSA:3.40.10.10 11 82 7.9E-27 T 12-10-2018 IPR035451 Ada-like domain superfamily TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 Pfam PF12833 Helix-turn-helix domain 116 195 3.0E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_13795 79a5e49b40798109ff47eb819b1fef66 505 Pfam PF02805 Metal binding domain of Ada 18 81 1.7E-26 T 12-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 TL08_04440 11a9033b54df6b364acfd8848508c832 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 304 5.7E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_04440 11a9033b54df6b364acfd8848508c832 308 SUPERFAMILY SSF161098 99 285 5.63E-28 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04440 11a9033b54df6b364acfd8848508c832 308 Gene3D G3DSA:1.10.3720.10 92 299 9.8E-22 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04440 11a9033b54df6b364acfd8848508c832 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 30 69 1.1E-14 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TL08_17690 1f23fd3ad8918bbdd846e0f20454a278 587 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 577 3.5E-142 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 TL08_17690 1f23fd3ad8918bbdd846e0f20454a278 587 Pfam PF02652 L-lactate permease 15 577 2.8E-142 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 TL08_02675 93f6265292b8b334379720eee62dd9c8 340 Pfam PF00348 Polyprenyl synthetase 50 288 2.9E-60 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TL08_02675 93f6265292b8b334379720eee62dd9c8 340 SUPERFAMILY SSF48576 27 339 2.24E-83 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_02675 93f6265292b8b334379720eee62dd9c8 340 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 220 232 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TL08_02675 93f6265292b8b334379720eee62dd9c8 340 Gene3D G3DSA:1.10.600.10 11 340 4.5E-107 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_09695 2280714c4619baa68ffc942258be5f46 388 SUPERFAMILY SSF51905 1 318 1.84E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09695 2280714c4619baa68ffc942258be5f46 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.1E-16 T 12-10-2018 TL08_09695 2280714c4619baa68ffc942258be5f46 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 2.1E-16 T 12-10-2018 TL08_09695 2280714c4619baa68ffc942258be5f46 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 2.1E-16 T 12-10-2018 TL08_09695 2280714c4619baa68ffc942258be5f46 388 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 7.5E-14 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_09695 2280714c4619baa68ffc942258be5f46 388 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 139 163 7.5E-14 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_09695 2280714c4619baa68ffc942258be5f46 388 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 7.5E-14 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_09695 2280714c4619baa68ffc942258be5f46 388 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 279 7.5E-14 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_09695 2280714c4619baa68ffc942258be5f46 388 Gene3D G3DSA:3.50.50.100 2 375 1.1E-77 T 12-10-2018 TL08_09695 2280714c4619baa68ffc942258be5f46 388 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 289 2.5E-42 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_09105 06ab9e7914b534ae7ecea27d01c7ccf3 509 SMART SM00490 319 400 1.7E-31 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_09105 06ab9e7914b534ae7ecea27d01c7ccf3 509 Pfam PF00271 Helicase conserved C-terminal domain 303 400 1.8E-25 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_09105 06ab9e7914b534ae7ecea27d01c7ccf3 509 Gene3D G3DSA:3.40.50.300 292 444 5.9E-45 T 12-10-2018 TL08_09105 06ab9e7914b534ae7ecea27d01c7ccf3 509 Gene3D G3DSA:3.40.50.300 43 273 2.4E-71 T 12-10-2018 TL08_09105 06ab9e7914b534ae7ecea27d01c7ccf3 509 SMART SM00487 85 285 2.1E-50 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_09105 06ab9e7914b534ae7ecea27d01c7ccf3 509 Pfam PF00270 DEAD/DEAH box helicase 90 256 9.5E-41 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_09105 06ab9e7914b534ae7ecea27d01c7ccf3 509 SUPERFAMILY SSF52540 138 415 1.82E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21165 043d4f1674a243b85f23c98c05447ea5 172 Gene3D G3DSA:1.10.10.10 4 95 6.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21165 043d4f1674a243b85f23c98c05447ea5 172 SUPERFAMILY SSF46785 7 165 1.82E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_21165 043d4f1674a243b85f23c98c05447ea5 172 Pfam PF03551 Transcriptional regulator PadR-like family 10 81 8.2E-13 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal TL08_13895 a0ab9586a616fe74217d4bcf13d39dd5 254 Gene3D G3DSA:3.40.50.150 24 188 9.1E-22 T 12-10-2018 TL08_13895 a0ab9586a616fe74217d4bcf13d39dd5 254 Pfam PF13649 Methyltransferase domain 60 157 2.5E-10 T 12-10-2018 TL08_13895 a0ab9586a616fe74217d4bcf13d39dd5 254 SUPERFAMILY SSF53335 26 241 3.22E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_10005 3922db3229b65e7889794d42bfbd5a23 451 Gene3D G3DSA:1.25.40.10 300 438 8.2E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10005 3922db3229b65e7889794d42bfbd5a23 451 SUPERFAMILY SSF48452 221 440 1.9E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10005 3922db3229b65e7889794d42bfbd5a23 451 Gene3D G3DSA:1.25.40.10 215 295 4.2E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10005 3922db3229b65e7889794d42bfbd5a23 451 SMART SM00028 363 396 81.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10005 3922db3229b65e7889794d42bfbd5a23 451 SMART SM00028 403 436 170.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10005 3922db3229b65e7889794d42bfbd5a23 451 SMART SM00028 236 269 16.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_10005 3922db3229b65e7889794d42bfbd5a23 451 SMART SM00028 323 356 54.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_13835 afe42abf9dbc6d6dc55d2407083c1723 345 PRINTS PR00069 Aldo-keto reductase signature 41 65 2.4E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_13835 afe42abf9dbc6d6dc55d2407083c1723 345 PRINTS PR00069 Aldo-keto reductase signature 135 152 2.4E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_13835 afe42abf9dbc6d6dc55d2407083c1723 345 PRINTS PR00069 Aldo-keto reductase signature 104 122 2.4E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_13835 afe42abf9dbc6d6dc55d2407083c1723 345 SUPERFAMILY SSF51430 2 308 4.19E-87 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_13835 afe42abf9dbc6d6dc55d2407083c1723 345 Gene3D G3DSA:3.20.20.100 1 326 6.5E-101 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_13835 afe42abf9dbc6d6dc55d2407083c1723 345 Pfam PF00248 Aldo/keto reductase family 16 307 7.2E-65 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_27140 6004d403549f3219d05b5e0c30002e41 363 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 32 248 7.7E-56 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_27140 6004d403549f3219d05b5e0c30002e41 363 Pfam PF02096 60Kd inner membrane protein 32 248 3.2E-51 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PIRSF PIRSF000350 8 491 8.3E-70 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 Gene3D G3DSA:3.30.390.30 381 495 1.4E-25 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 Gene3D G3DSA:3.50.50.60 28 353 1.3E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 28 339 6.8E-49 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 SUPERFAMILY SSF51905 22 357 5.26E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 Gene3D G3DSA:3.50.50.60 178 296 1.3E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 327 334 7.2E-53 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 465 485 7.2E-53 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 61 76 7.2E-53 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 29 51 7.2E-53 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 171 7.2E-53 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 443 458 7.2E-53 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 399 7.2E-53 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 198 223 7.2E-53 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 297 7.2E-53 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 382 486 4.5E-21 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 SUPERFAMILY SSF55424 378 492 9.11E-27 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 198 216 4.6E-21 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 4.6E-21 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 30 49 4.6E-21 T 12-10-2018 TL08_22245 1ca0f8492b857d8e41fdbd9431d7ed9a 496 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 298 4.6E-21 T 12-10-2018 TL08_09605 0b947189620944d51b5e8569e321fe60 406 SUPERFAMILY SSF48264 17 405 2.1E-104 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 Gene3D G3DSA:1.10.630.10 2 406 1.3E-139 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 PRINTS PR00359 B-class P450 signature 294 321 1.5E-61 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 PRINTS PR00359 B-class P450 signature 195 217 1.5E-61 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 PRINTS PR00359 B-class P450 signature 343 352 1.5E-61 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 PRINTS PR00359 B-class P450 signature 138 154 1.5E-61 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 PRINTS PR00359 B-class P450 signature 276 287 1.5E-61 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 PRINTS PR00359 B-class P450 signature 352 363 1.5E-61 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 PRINTS PR00359 B-class P450 signature 92 103 1.5E-61 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 PRINTS PR00359 B-class P450 signature 155 170 1.5E-61 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 PRINTS PR00359 B-class P450 signature 322 337 1.5E-61 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 Pfam PF00067 Cytochrome P450 182 373 5.5E-23 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_09605 0b947189620944d51b5e8569e321fe60 406 Pfam PF00067 Cytochrome P450 33 138 3.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_02185 026c14cb0837ef2dcf100dd72101ca28 118 Gene3D G3DSA:1.10.260.40 12 78 1.5E-17 T 12-10-2018 TL08_02185 026c14cb0837ef2dcf100dd72101ca28 118 SMART SM00530 18 73 1.5E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_02185 026c14cb0837ef2dcf100dd72101ca28 118 Pfam PF01381 Helix-turn-helix 19 71 1.3E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_02185 026c14cb0837ef2dcf100dd72101ca28 118 SUPERFAMILY SSF47413 13 74 1.04E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_15425 c43db22494536e8b7f07193a4baba2cb 307 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 98 299 38.683 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_15425 c43db22494536e8b7f07193a4baba2cb 307 Pfam PF00574 Clp protease 124 297 3.3E-73 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TL08_15425 c43db22494536e8b7f07193a4baba2cb 307 PRINTS PR00127 Clp protease catalytic subunit P signature 165 185 2.9E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_15425 c43db22494536e8b7f07193a4baba2cb 307 PRINTS PR00127 Clp protease catalytic subunit P signature 125 140 2.9E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_15425 c43db22494536e8b7f07193a4baba2cb 307 PRINTS PR00127 Clp protease catalytic subunit P signature 274 293 2.9E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_15425 c43db22494536e8b7f07193a4baba2cb 307 PRINTS PR00127 Clp protease catalytic subunit P signature 217 236 2.9E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_15425 c43db22494536e8b7f07193a4baba2cb 307 PRINTS PR00127 Clp protease catalytic subunit P signature 196 213 2.9E-42 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_15425 c43db22494536e8b7f07193a4baba2cb 307 Gene3D G3DSA:3.90.226.10 100 303 1.9E-69 T 12-10-2018 TL08_15425 c43db22494536e8b7f07193a4baba2cb 307 SUPERFAMILY SSF52096 126 296 3.9E-62 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_01360 d5e9cc997d0b1516dd70e77b326912ef 668 Gene3D G3DSA:3.40.50.12780 70 532 4.1E-101 T 12-10-2018 TL08_01360 d5e9cc997d0b1516dd70e77b326912ef 668 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 42 95 5.1E-23 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TL08_01360 d5e9cc997d0b1516dd70e77b326912ef 668 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 38 658 3.8E-291 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 TL08_01360 d5e9cc997d0b1516dd70e77b326912ef 668 Pfam PF13193 AMP-binding enzyme C-terminal domain 548 627 1.5E-27 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_01360 d5e9cc997d0b1516dd70e77b326912ef 668 ProSitePatterns PS00455 Putative AMP-binding domain signature. 273 284 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_01360 d5e9cc997d0b1516dd70e77b326912ef 668 Pfam PF00501 AMP-binding enzyme 102 539 5.2E-90 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_01360 d5e9cc997d0b1516dd70e77b326912ef 668 SUPERFAMILY SSF56801 40 656 9.55E-173 T 12-10-2018 TL08_01360 d5e9cc997d0b1516dd70e77b326912ef 668 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 23 661 50.471 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 TL08_01360 d5e9cc997d0b1516dd70e77b326912ef 668 Gene3D G3DSA:3.30.300.30 535 663 9.0E-31 T 12-10-2018 TL08_18810 7aed5b9beeaa83d2d88d2f200a8c5e79 239 Pfam PF13411 MerR HTH family regulatory protein 4 68 6.1E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_18810 7aed5b9beeaa83d2d88d2f200a8c5e79 239 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 3.7E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_18810 7aed5b9beeaa83d2d88d2f200a8c5e79 239 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 3.7E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_18810 7aed5b9beeaa83d2d88d2f200a8c5e79 239 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 3.7E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_18810 7aed5b9beeaa83d2d88d2f200a8c5e79 239 Gene3D G3DSA:1.10.1660.10 6 199 2.4E-28 T 12-10-2018 TL08_18810 7aed5b9beeaa83d2d88d2f200a8c5e79 239 SUPERFAMILY SSF46955 3 105 4.03E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_18810 7aed5b9beeaa83d2d88d2f200a8c5e79 239 SMART SM00422 3 72 6.7E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 Gene3D G3DSA:3.40.50.1820 16 695 3.1E-206 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 17 427 1.7E-68 T 12-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 627 649 4.3E-45 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 553 573 4.3E-45 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 608 623 4.3E-45 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 469 487 4.3E-45 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 523 542 4.3E-45 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 495 519 4.3E-45 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 Pfam PF00326 Prolyl oligopeptidase family 487 699 5.9E-49 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 SUPERFAMILY SSF53474 441 696 1.09E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 Gene3D G3DSA:2.130.10.120 75 430 3.1E-206 T 12-10-2018 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 SUPERFAMILY SSF50993 6 426 1.6E-66 T 12-10-2018 TL08_07895 87758dc5ed4e49e7e26b7eee8d05ec58 705 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 530 560 - T 12-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 TL08_15330 a28cdcc2cc4c8283f5fa6fadc7289e97 187 Pfam PF13569 Domain of unknown function (DUF4132) 4 99 3.6E-20 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_00775 95f4db26589d8b8aecaedba4e985d632 355 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TL08_00775 95f4db26589d8b8aecaedba4e985d632 355 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 354 48.919 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TL08_00775 95f4db26589d8b8aecaedba4e985d632 355 Pfam PF00155 Aminotransferase class I and II 25 348 8.3E-47 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_00775 95f4db26589d8b8aecaedba4e985d632 355 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 5 355 46.141 T 12-10-2018 IPR024892 Putative phenylalanine aminotransferase TL08_00775 95f4db26589d8b8aecaedba4e985d632 355 Gene3D G3DSA:3.40.640.10 36 266 1.8E-122 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_00775 95f4db26589d8b8aecaedba4e985d632 355 Gene3D G3DSA:3.90.1150.10 10 347 1.8E-122 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_00775 95f4db26589d8b8aecaedba4e985d632 355 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 351 5.0E-88 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TL08_00775 95f4db26589d8b8aecaedba4e985d632 355 SUPERFAMILY SSF53383 19 351 1.38E-72 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_14765 12a7b8de4652ce21fed9e4debd3842d1 107 Gene3D G3DSA:3.10.20.440 11 104 7.4E-18 T 12-10-2018 TL08_14765 12a7b8de4652ce21fed9e4debd3842d1 107 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 22 99 1.7E-23 T 12-10-2018 TL08_14765 12a7b8de4652ce21fed9e4debd3842d1 107 SUPERFAMILY SSF54292 23 106 4.33E-16 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TL08_18345 a9b5898854e77c4094b5d14a35eaa80d 101 Gene3D G3DSA:1.10.1200.10 6 95 2.1E-8 T 12-10-2018 IPR036736 ACP-like superfamily TL08_18345 a9b5898854e77c4094b5d14a35eaa80d 101 SUPERFAMILY SSF47336 11 99 8.0E-8 T 12-10-2018 IPR036736 ACP-like superfamily TL08_07315 17607d1621e20e516f058ec060a96c83 182 Pfam PF00430 ATP synthase B/B' CF(0) 23 151 1.9E-28 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TL08_07315 17607d1621e20e516f058ec060a96c83 182 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 27 173 2.0E-29 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 TL08_07315 17607d1621e20e516f058ec060a96c83 182 Gene3D G3DSA:1.20.5.620 78 138 5.8E-8 T 12-10-2018 TL08_07315 17607d1621e20e516f058ec060a96c83 182 SUPERFAMILY SSF81573 79 137 6.93E-14 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily TL08_07315 17607d1621e20e516f058ec060a96c83 182 Hamap MF_01398 ATP synthase subunit b [atpF]. 17 154 13.031 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TL08_14070 a0fc5e560dd86b2f154d5069b7be61a2 499 Pfam PF07690 Major Facilitator Superfamily 40 442 1.1E-55 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_14070 a0fc5e560dd86b2f154d5069b7be61a2 499 Gene3D G3DSA:1.20.1250.20 286 496 5.0E-21 T 12-10-2018 TL08_14070 a0fc5e560dd86b2f154d5069b7be61a2 499 Gene3D G3DSA:1.20.1720.10 36 235 7.3E-51 T 12-10-2018 TL08_14070 a0fc5e560dd86b2f154d5069b7be61a2 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 359 379 2.4E-14 T 12-10-2018 TL08_14070 a0fc5e560dd86b2f154d5069b7be61a2 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 159 183 2.4E-14 T 12-10-2018 TL08_14070 a0fc5e560dd86b2f154d5069b7be61a2 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 149 2.4E-14 T 12-10-2018 TL08_14070 a0fc5e560dd86b2f154d5069b7be61a2 499 PRINTS PR01036 Tetracycline resistance protein TetB signature 38 62 2.4E-14 T 12-10-2018 TL08_14070 a0fc5e560dd86b2f154d5069b7be61a2 499 SUPERFAMILY SSF103473 33 495 1.57E-65 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_23110 9219640d4fdd15d2114fb57d4f476086 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 211 2.4E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_23110 9219640d4fdd15d2114fb57d4f476086 223 SUPERFAMILY SSF161098 18 203 1.57E-27 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23110 9219640d4fdd15d2114fb57d4f476086 223 Gene3D G3DSA:1.10.3720.10 12 211 1.7E-24 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23850 d796e3fcd2cbc243373d8242a339daaa 392 Pfam PF01261 Xylose isomerase-like TIM barrel 42 223 1.1E-9 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_23850 d796e3fcd2cbc243373d8242a339daaa 392 SUPERFAMILY SSF51658 7 240 5.5E-27 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_23850 d796e3fcd2cbc243373d8242a339daaa 392 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 200 207 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 TL08_23850 d796e3fcd2cbc243373d8242a339daaa 392 Gene3D G3DSA:3.20.20.150 24 285 4.1E-14 T 12-10-2018 TL08_19985 d207c303c09c4c18f1a592af98e6426a 150 Gene3D G3DSA:3.30.450.30 13 139 5.7E-39 T 12-10-2018 TL08_19985 d207c303c09c4c18f1a592af98e6426a 150 Pfam PF03259 Roadblock/LC7 domain 17 108 1.6E-24 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TL08_19985 d207c303c09c4c18f1a592af98e6426a 150 SMART SM00960 18 108 1.2E-28 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TL08_19985 d207c303c09c4c18f1a592af98e6426a 150 SUPERFAMILY SSF103196 9 137 8.72E-35 T 12-10-2018 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 Gene3D G3DSA:1.10.287.990 21 84 2.8E-22 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 84 3.6E-26 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 5.6E-33 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 SUPERFAMILY SSF46609 3 88 5.24E-27 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 PIRSF PIRSF000349 1 202 7.8E-67 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 5.9E-17 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 5.9E-17 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 5.9E-17 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 5.9E-17 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 5.9E-17 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 Gene3D G3DSA:2.40.500.20 85 206 1.6E-41 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_17320 99ffc67298d19e810fdb746e619d7272 209 SUPERFAMILY SSF54719 84 197 3.93E-40 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_02260 6847481b37d30a4a3f6419c59ee51e85 253 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 121 2.1E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_02260 6847481b37d30a4a3f6419c59ee51e85 253 Gene3D G3DSA:3.10.180.10 135 253 2.8E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_02260 6847481b37d30a4a3f6419c59ee51e85 253 Gene3D G3DSA:3.10.180.10 8 128 1.8E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_02260 6847481b37d30a4a3f6419c59ee51e85 253 SUPERFAMILY SSF54593 14 187 3.9E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_11880 70f10319842b60c74520b42d21ca21b7 199 Gene3D G3DSA:3.40.50.150 14 175 7.2E-6 T 12-10-2018 TL08_11880 70f10319842b60c74520b42d21ca21b7 199 Gene3D G3DSA:2.20.130.10 102 162 7.2E-6 T 12-10-2018 TL08_11880 70f10319842b60c74520b42d21ca21b7 199 SUPERFAMILY SSF53335 26 184 1.2E-5 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_09985 338e08a5a59e27f38b3651e23fb9bf61 154 Pfam PF07883 Cupin domain 76 131 5.7E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TL08_09985 338e08a5a59e27f38b3651e23fb9bf61 154 Gene3D G3DSA:2.60.120.10 45 151 4.0E-28 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_09985 338e08a5a59e27f38b3651e23fb9bf61 154 SUPERFAMILY SSF51182 40 142 2.97E-22 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_09985 338e08a5a59e27f38b3651e23fb9bf61 154 PIRSF PIRSF029883 38 153 8.9E-25 T 12-10-2018 IPR025499 Pectin degradation protein KdgF TL08_16735 8dcb963ed608ea153d3a450332ee2139 279 SUPERFAMILY SSF51569 2 271 1.47E-79 T 12-10-2018 TL08_16735 8dcb963ed608ea153d3a450332ee2139 279 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 275 3.0E-82 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TL08_16735 8dcb963ed608ea153d3a450332ee2139 279 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 7 270 3.4E-68 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TL08_16735 8dcb963ed608ea153d3a450332ee2139 279 PIRSF PIRSF001359 1 278 4.8E-75 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TL08_16735 8dcb963ed608ea153d3a450332ee2139 279 Gene3D G3DSA:3.20.20.70 1 277 9.0E-88 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_17170 fbeacb5f5466add85b700ff9e74d1012 188 SUPERFAMILY SSF56214 3 69 2.25E-5 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_18305 8b5cc5ba09b577c76b66ebe4d022f2b9 156 PRINTS PR00502 NUDIX hydrolase family signature 38 52 2.2E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_18305 8b5cc5ba09b577c76b66ebe4d022f2b9 156 PRINTS PR00502 NUDIX hydrolase family signature 53 68 2.2E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_18305 8b5cc5ba09b577c76b66ebe4d022f2b9 156 Gene3D G3DSA:3.90.79.10 2 138 3.1E-17 T 12-10-2018 TL08_18305 8b5cc5ba09b577c76b66ebe4d022f2b9 156 SUPERFAMILY SSF55811 7 134 1.35E-19 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_18305 8b5cc5ba09b577c76b66ebe4d022f2b9 156 Pfam PF00293 NUDIX domain 10 107 9.9E-13 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_04450 97053476a83b515077a0cd669b0ee25f 354 SUPERFAMILY SSF52540 25 277 3.85E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04450 97053476a83b515077a0cd669b0ee25f 354 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 257 324 5.8E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_04450 97053476a83b515077a0cd669b0ee25f 354 SMART SM00382 62 255 1.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_04450 97053476a83b515077a0cd669b0ee25f 354 Gene3D G3DSA:3.40.50.300 23 352 7.2E-104 T 12-10-2018 TL08_04450 97053476a83b515077a0cd669b0ee25f 354 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 255 345 4.9E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_04450 97053476a83b515077a0cd669b0ee25f 354 Pfam PF00005 ABC transporter 54 205 3.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_04450 97053476a83b515077a0cd669b0ee25f 354 ProSitePatterns PS00211 ABC transporters family signature. 178 192 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_23590 dd151fdcb80fb577416740150cd5ca15 240 Pfam PF01955 Adenosylcobinamide amidohydrolase 32 212 9.7E-46 T 12-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ TL08_20320 38a68c562148c9664b1faaa0276123e1 205 Pfam PF04343 Protein of unknown function, DUF488 32 159 8.8E-25 T 12-10-2018 IPR007438 Protein of unknown function DUF488 TL08_20320 38a68c562148c9664b1faaa0276123e1 205 PIRSF PIRSF024492 17 204 3.4E-42 T 12-10-2018 IPR014519 Uncharacterised conserved protein UCP024492 TL08_09930 85a635bcb931d34e146b346c67260b49 451 Pfam PF04542 Sigma-70 region 2 20 80 5.6E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_09930 85a635bcb931d34e146b346c67260b49 451 Pfam PF08281 Sigma-70, region 4 124 172 3.1E-9 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_09930 85a635bcb931d34e146b346c67260b49 451 Gene3D G3DSA:1.10.1740.10 7 81 5.4E-8 T 12-10-2018 TL08_09930 85a635bcb931d34e146b346c67260b49 451 SUPERFAMILY SSF88946 6 83 9.42E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_09930 85a635bcb931d34e146b346c67260b49 451 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 175 2.0E-14 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_09930 85a635bcb931d34e146b346c67260b49 451 Gene3D G3DSA:1.10.10.10 91 176 6.7E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_09930 85a635bcb931d34e146b346c67260b49 451 SUPERFAMILY SSF88659 111 174 3.18E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 Pfam PF06827 Zinc finger found in FPG and IleRS 290 318 1.3E-7 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 SUPERFAMILY SSF57716 269 318 2.79E-15 T 12-10-2018 TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 SUPERFAMILY SSF46946 176 266 1.1E-25 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 SMART SM00898 2 158 1.3E-48 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 318 40.232 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 SUPERFAMILY SSF81624 2 186 2.75E-35 T 12-10-2018 IPR035937 MutM-like, N-terminal TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 Gene3D G3DSA:1.10.8.50 179 318 2.7E-42 T 12-10-2018 TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 156 1.4E-34 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 177 264 1.3E-20 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 317 1.0E-82 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TL08_22380 bbb977289cefb0331ea728ef6eb92ca4 325 SMART SM01232 177 269 5.2E-39 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TL08_13625 74d369cab520a9142fbe5e45f1774aa8 369 SUPERFAMILY SSF51679 1 333 3.14E-71 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_13625 74d369cab520a9142fbe5e45f1774aa8 369 Gene3D G3DSA:3.20.20.30 1 344 1.8E-67 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_13625 74d369cab520a9142fbe5e45f1774aa8 369 Pfam PF00296 Luciferase-like monooxygenase 1 291 6.6E-56 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_13625 74d369cab520a9142fbe5e45f1774aa8 369 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 354 5.3E-215 T 12-10-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative TL08_23295 be872500919680a3f43a04219e27d23c 260 SMART SM00448 38 148 2.9E-46 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_23295 be872500919680a3f43a04219e27d23c 260 Gene3D G3DSA:3.40.50.2300 34 160 1.4E-38 T 12-10-2018 TL08_23295 be872500919680a3f43a04219e27d23c 260 Gene3D G3DSA:1.10.10.10 161 260 4.8E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23295 be872500919680a3f43a04219e27d23c 260 Pfam PF00486 Transcriptional regulatory protein, C terminal 181 256 5.5E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_23295 be872500919680a3f43a04219e27d23c 260 Pfam PF00072 Response regulator receiver domain 40 149 6.4E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_23295 be872500919680a3f43a04219e27d23c 260 SMART SM00862 181 257 1.1E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_23295 be872500919680a3f43a04219e27d23c 260 SUPERFAMILY SSF52172 38 214 2.85E-44 T 12-10-2018 IPR011006 CheY-like superfamily TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 SMART SM00421 151 208 1.8E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 4.4E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 SMART SM00448 5 116 1.4E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 SUPERFAMILY SSF52172 4 175 3.89E-31 T 12-10-2018 IPR011006 CheY-like superfamily TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 Pfam PF00072 Response regulator receiver domain 7 116 5.3E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_11755 2bf8c2d8a3804c0acebf5735c983b5bc 218 Gene3D G3DSA:3.40.50.12740 5 214 7.1E-61 T 12-10-2018 TL08_14865 7293a358aeaf3dd921e9ffdba981bf39 87 Gene3D G3DSA:1.10.1200.10 7 86 8.2E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14865 7293a358aeaf3dd921e9ffdba981bf39 87 ProSitePatterns PS00012 Phosphopantetheine attachment site. 41 56 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_14865 7293a358aeaf3dd921e9ffdba981bf39 87 SUPERFAMILY SSF47336 13 80 1.44E-13 T 12-10-2018 IPR036736 ACP-like superfamily TL08_14865 7293a358aeaf3dd921e9ffdba981bf39 87 Pfam PF00550 Phosphopantetheine attachment site 19 80 6.4E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_23675 f6c7d1c5754f162033bc93849fd247d8 345 Pfam PF13560 Helix-turn-helix domain 72 134 2.0E-13 T 12-10-2018 TL08_23675 f6c7d1c5754f162033bc93849fd247d8 345 SMART SM00530 76 131 1.7E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_23675 f6c7d1c5754f162033bc93849fd247d8 345 SUPERFAMILY SSF47413 62 130 1.63E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_23675 f6c7d1c5754f162033bc93849fd247d8 345 Gene3D G3DSA:1.10.260.40 65 130 5.5E-12 T 12-10-2018 TL08_17745 b815ffafd47b8fa021a87d8fab75963f 237 Pfam PF13398 Peptidase M50B-like 27 227 2.1E-56 T 12-10-2018 TL08_02745 e883ca2530b9ba3499be413327d94b39 232 SMART SM00849 17 212 3.4E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_02745 e883ca2530b9ba3499be413327d94b39 232 Gene3D G3DSA:3.60.15.10 1 231 6.5E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_02745 e883ca2530b9ba3499be413327d94b39 232 SUPERFAMILY SSF56281 2 227 1.04E-45 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_02745 e883ca2530b9ba3499be413327d94b39 232 Pfam PF00753 Metallo-beta-lactamase superfamily 15 212 8.6E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_18730 0a6830350ee85b3804cd7a18540f5283 167 Pfam PF04978 Protein of unknown function (DUF664) 23 164 5.1E-44 T 12-10-2018 IPR007061 Protein of unknown function DUF664 TL08_18730 0a6830350ee85b3804cd7a18540f5283 167 SUPERFAMILY SSF109854 16 164 1.53E-37 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_18730 0a6830350ee85b3804cd7a18540f5283 167 Gene3D G3DSA:1.20.120.450 6 165 2.0E-32 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 SUPERFAMILY SSF52540 12 262 1.49E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 Gene3D G3DSA:3.40.50.300 318 574 1.6E-76 T 12-10-2018 TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 Gene3D G3DSA:3.40.50.300 10 308 3.6E-86 T 12-10-2018 TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 Pfam PF00005 ABC transporter 344 494 2.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 SUPERFAMILY SSF52540 321 566 2.13E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 ProSitePatterns PS00211 ABC transporters family signature. 467 481 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 SMART SM00382 41 240 1.5E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 SMART SM00382 352 544 7.0E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 276 9.4E-5 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 546 571 0.074 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_17060 bfb5a125f56a82653ac5f5a46135f2ad 577 Pfam PF00005 ABC transporter 33 191 1.0E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_14490 602c8f2c29e5527f993ae5fbcdd89023 577 SUPERFAMILY SSF52540 326 566 5.33E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14490 602c8f2c29e5527f993ae5fbcdd89023 577 SUPERFAMILY SSF90123 11 318 2.49E-34 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_14490 602c8f2c29e5527f993ae5fbcdd89023 577 Gene3D G3DSA:3.40.50.300 326 575 7.5E-78 T 12-10-2018 TL08_14490 602c8f2c29e5527f993ae5fbcdd89023 577 Gene3D G3DSA:1.20.1560.10 2 314 1.1E-28 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_14490 602c8f2c29e5527f993ae5fbcdd89023 577 SMART SM00382 358 544 7.0E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_14490 602c8f2c29e5527f993ae5fbcdd89023 577 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_14490 602c8f2c29e5527f993ae5fbcdd89023 577 Pfam PF00664 ABC transporter transmembrane region 40 275 6.5E-14 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_14490 602c8f2c29e5527f993ae5fbcdd89023 577 Pfam PF00005 ABC transporter 349 498 5.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_14415 083603ce6507f66b236ebcba19b045b6 263 Pfam PF00975 Thioesterase domain 24 241 2.6E-49 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_14415 083603ce6507f66b236ebcba19b045b6 263 SUPERFAMILY SSF53474 2 248 7.3E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14415 083603ce6507f66b236ebcba19b045b6 263 Gene3D G3DSA:3.40.50.1820 4 249 2.9E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13360 b488ea78a3b4b8b0599daacaf779bb6c 332 SUPERFAMILY SSF53335 22 207 5.69E-11 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13360 b488ea78a3b4b8b0599daacaf779bb6c 332 Gene3D G3DSA:3.40.50.150 6 208 1.6E-11 T 12-10-2018 TL08_13360 b488ea78a3b4b8b0599daacaf779bb6c 332 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 42 316 1.8E-80 T 12-10-2018 IPR015324 Ribosomal protein Rsm22-like GO:0006412|GO:0008168 TL08_17780 2bae9b7802ec30a983dfa5637faa8d39 439 PIRSF PIRSF003085 41 439 2.3E-115 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 TL08_17780 2bae9b7802ec30a983dfa5637faa8d39 439 SUPERFAMILY SSF53335 159 438 9.05E-69 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_17780 2bae9b7802ec30a983dfa5637faa8d39 439 Pfam PF02353 Mycolic acid cyclopropane synthetase 153 433 1.5E-83 T 12-10-2018 TL08_17780 2bae9b7802ec30a983dfa5637faa8d39 439 Gene3D G3DSA:3.40.50.150 157 439 7.2E-92 T 12-10-2018 TL08_04285 5f3c564554354c5a6c5158398002eb81 328 Pfam PF04909 Amidohydrolase 10 320 3.6E-38 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_04285 5f3c564554354c5a6c5158398002eb81 328 Gene3D G3DSA:3.20.20.140 9 322 1.6E-72 T 12-10-2018 TL08_04285 5f3c564554354c5a6c5158398002eb81 328 SUPERFAMILY SSF51556 10 320 4.54E-68 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_24250 634b5feea2f062d7ee064f94d473f750 315 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 3.9E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_24250 634b5feea2f062d7ee064f94d473f750 315 SUPERFAMILY SSF51735 114 260 2.84E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24250 634b5feea2f062d7ee064f94d473f750 315 Pfam PF13602 Zinc-binding dehydrogenase 182 313 8.7E-15 T 12-10-2018 TL08_24250 634b5feea2f062d7ee064f94d473f750 315 Gene3D G3DSA:3.90.180.10 11 312 1.9E-65 T 12-10-2018 TL08_24250 634b5feea2f062d7ee064f94d473f750 315 SUPERFAMILY SSF50129 2 148 2.83E-26 T 12-10-2018 IPR011032 GroES-like superfamily TL08_24250 634b5feea2f062d7ee064f94d473f750 315 SMART SM00829 7 313 5.0E-12 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_24250 634b5feea2f062d7ee064f94d473f750 315 Gene3D G3DSA:3.40.50.720 123 256 1.9E-65 T 12-10-2018 TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 1.9E-59 T 12-10-2018 TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 SUPERFAMILY SSF51735 7 244 3.4E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 191 8.4E-5 T 12-10-2018 TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 9.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 9.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.3E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.3E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 8.3E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 8.3E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 8.3E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_10425 d1cf10877e9c7d472fd8fe1e2c45e45c 245 Gene3D G3DSA:3.40.50.720 1 244 5.9E-74 T 12-10-2018 TL08_05210 1c79f3e99947c88d972fc8cf6d4c83ec 409 SMART SM00833 249 365 4.7E-28 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TL08_05210 1c79f3e99947c88d972fc8cf6d4c83ec 409 SUPERFAMILY SSF90002 250 365 1.57E-8 T 12-10-2018 TL08_05210 1c79f3e99947c88d972fc8cf6d4c83ec 409 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 252 365 5.1E-15 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TL08_05210 1c79f3e99947c88d972fc8cf6d4c83ec 409 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 33 190 1.1E-6 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TL08_05210 1c79f3e99947c88d972fc8cf6d4c83ec 409 Gene3D G3DSA:3.40.50.300 19 221 3.0E-12 T 12-10-2018 TL08_24360 468c822add4231b84cddc084385b1c17 304 Gene3D G3DSA:3.40.50.300 2 230 3.9E-58 T 12-10-2018 TL08_24360 468c822add4231b84cddc084385b1c17 304 Pfam PF00005 ABC transporter 21 157 2.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_24360 468c822add4231b84cddc084385b1c17 304 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_24360 468c822add4231b84cddc084385b1c17 304 SMART SM00382 30 206 3.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_24360 468c822add4231b84cddc084385b1c17 304 SUPERFAMILY SSF52540 8 221 2.42E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03910 6f369dbcfc8a293a90c6104dcd46cbf5 311 SUPERFAMILY SSF161098 43 307 7.76E-75 T 12-10-2018 IPR035906 MetI-like superfamily TL08_03910 6f369dbcfc8a293a90c6104dcd46cbf5 311 Gene3D G3DSA:1.10.3720.10 34 301 2.0E-70 T 12-10-2018 IPR035906 MetI-like superfamily TL08_03910 6f369dbcfc8a293a90c6104dcd46cbf5 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 303 7.1E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 Gene3D G3DSA:3.40.50.300 274 431 5.0E-25 T 12-10-2018 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 Gene3D G3DSA:1.25.40.10 852 1013 6.5E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 Gene3D G3DSA:1.25.40.10 701 851 6.9E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 Gene3D G3DSA:1.25.40.10 95 253 3.7E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SUPERFAMILY SSF52540 278 545 5.03E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 Gene3D G3DSA:1.10.10.10 1 93 1.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 Pfam PF03704 Bacterial transcriptional activator domain 97 238 3.2E-26 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SUPERFAMILY SSF46894 2 89 4.76E-5 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SUPERFAMILY SSF48452 92 251 3.11E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SUPERFAMILY SSF48452 774 962 3.67E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SMART SM01043 97 242 2.8E-25 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 PRINTS PR00364 Disease resistance protein signature 311 326 3.2E-10 T 12-10-2018 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 PRINTS PR00364 Disease resistance protein signature 389 403 3.2E-10 T 12-10-2018 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 PRINTS PR00364 Disease resistance protein signature 476 490 3.2E-10 T 12-10-2018 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 Pfam PF00931 NB-ARC domain 309 551 5.8E-12 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SMART SM00028 935 968 310.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SMART SM00028 855 891 410.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SMART SM00028 812 845 25.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SMART SM00028 102 135 150.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SMART SM00028 895 928 0.26 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_06630 e3acffd0409f2a81a4137af84874ce32 1021 SMART SM00028 192 225 69.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_14825 3abb4b7d80bc65ad7ae7dea1c325ff94 473 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 52 85 - T 12-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 TL08_14825 3abb4b7d80bc65ad7ae7dea1c325ff94 473 SUPERFAMILY SSF56176 13 216 1.68E-41 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_14825 3abb4b7d80bc65ad7ae7dea1c325ff94 473 Gene3D G3DSA:3.30.43.10 27 103 2.3E-16 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TL08_14825 3abb4b7d80bc65ad7ae7dea1c325ff94 473 Pfam PF08031 Berberine and berberine like 438 467 1.6E-7 T 12-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 TL08_14825 3abb4b7d80bc65ad7ae7dea1c325ff94 473 Gene3D G3DSA:3.30.465.10 116 455 9.6E-95 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TL08_14825 3abb4b7d80bc65ad7ae7dea1c325ff94 473 Pfam PF01565 FAD binding domain 55 183 4.2E-22 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TL08_14825 3abb4b7d80bc65ad7ae7dea1c325ff94 473 Gene3D G3DSA:3.40.462.20 216 425 9.6E-95 T 12-10-2018 TL08_12860 427abe723a2ebe8e30cd465b55c0b0f8 180 SUPERFAMILY SSF88946 6 97 2.51E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_12860 427abe723a2ebe8e30cd465b55c0b0f8 180 SUPERFAMILY SSF88659 83 162 3.18E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_12860 427abe723a2ebe8e30cd465b55c0b0f8 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 159 4.7E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_12860 427abe723a2ebe8e30cd465b55c0b0f8 180 Pfam PF04542 Sigma-70 region 2 15 81 6.4E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_12860 427abe723a2ebe8e30cd465b55c0b0f8 180 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 6 161 6.0E-49 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 TL08_12860 427abe723a2ebe8e30cd465b55c0b0f8 180 Gene3D G3DSA:1.10.10.10 82 162 2.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12860 427abe723a2ebe8e30cd465b55c0b0f8 180 Pfam PF08281 Sigma-70, region 4 105 155 4.2E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_12860 427abe723a2ebe8e30cd465b55c0b0f8 180 Gene3D G3DSA:1.10.1740.10 3 81 8.2E-11 T 12-10-2018 TL08_20790 a8b1595ca51d0dc8f5b6f2282a042c5b 272 SMART SM00342 167 251 1.3E-14 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_20790 a8b1595ca51d0dc8f5b6f2282a042c5b 272 SUPERFAMILY SSF46689 205 255 2.78E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_20790 a8b1595ca51d0dc8f5b6f2282a042c5b 272 Pfam PF12833 Helix-turn-helix domain 174 252 3.4E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_20790 a8b1595ca51d0dc8f5b6f2282a042c5b 272 Gene3D G3DSA:1.10.10.60 151 259 2.4E-22 T 12-10-2018 TL08_25130 e3e6218f0bccd6a44526e12959bf0006 411 Pfam PF05977 Transmembrane secretion effector 7 399 4.5E-43 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_25130 e3e6218f0bccd6a44526e12959bf0006 411 SUPERFAMILY SSF103473 13 399 2.75E-37 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_25130 e3e6218f0bccd6a44526e12959bf0006 411 Gene3D G3DSA:1.20.1250.20 13 400 4.6E-33 T 12-10-2018 TL08_04520 97ad60b718f9056d0da6ab1c605d80dc 272 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 1 16 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_04520 97ad60b718f9056d0da6ab1c605d80dc 272 SUPERFAMILY SSF51717 1 261 3.14E-78 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_04520 97ad60b718f9056d0da6ab1c605d80dc 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 257 1.5E-82 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TL08_04520 97ad60b718f9056d0da6ab1c605d80dc 272 Pfam PF00809 Pterin binding enzyme 2 243 2.3E-68 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_04520 97ad60b718f9056d0da6ab1c605d80dc 272 Gene3D G3DSA:3.20.20.20 1 272 2.4E-86 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TL08_11910 dd9baa985b940f31de6d891dbdcc119a 130 SUPERFAMILY SSF46785 14 123 1.36E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_11910 dd9baa985b940f31de6d891dbdcc119a 130 Pfam PF01638 HxlR-like helix-turn-helix 28 110 1.7E-23 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_11910 dd9baa985b940f31de6d891dbdcc119a 130 Gene3D G3DSA:1.10.10.10 5 127 3.9E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 Gene3D G3DSA:3.40.50.300 1091 1326 1.8E-49 T 12-10-2018 TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 Pfam PF01580 FtsK/SpoIIIE family 812 1043 4.4E-51 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 Pfam PF01580 FtsK/SpoIIIE family 447 576 1.6E-22 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 SUPERFAMILY SSF52540 785 1019 4.14E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 697 2.2E-278 T 12-10-2018 IPR023836 EccCa-like, Actinobacteria TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 SMART SM00382 475 653 4.1 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 SMART SM00382 832 1008 0.22 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 SUPERFAMILY SSF52540 440 660 5.82E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 753 1322 4.4E-232 T 12-10-2018 IPR023837 EccCb-like, Actinobacteria TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 Gene3D G3DSA:3.40.50.300 775 1082 2.2E-90 T 12-10-2018 TL08_24950 a1867b95e431f40e8c717e2f0c0fd786 1329 Gene3D G3DSA:3.40.50.300 205 375 3.6E-9 T 12-10-2018 TL08_05030 b3363e5cedadd31f6c041b6973107eeb 463 Pfam PF00202 Aminotransferase class-III 60 452 6.8E-48 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_05030 b3363e5cedadd31f6c041b6973107eeb 463 Gene3D G3DSA:3.90.1150.10 60 447 1.7E-66 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_05030 b3363e5cedadd31f6c041b6973107eeb 463 SUPERFAMILY SSF53383 60 453 1.3E-62 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_05030 b3363e5cedadd31f6c041b6973107eeb 463 Gene3D G3DSA:3.40.640.10 77 346 1.7E-66 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_00785 f1842e87854fa92d1dceac0af2875a70 695 Pfam PF00501 AMP-binding enzyme 116 546 1.1E-51 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_00785 f1842e87854fa92d1dceac0af2875a70 695 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 8 667 1.7E-235 T 12-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 TL08_00785 f1842e87854fa92d1dceac0af2875a70 695 ProSitePatterns PS00455 Putative AMP-binding domain signature. 289 300 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_00785 f1842e87854fa92d1dceac0af2875a70 695 Gene3D G3DSA:3.40.50.12780 89 541 7.1E-66 T 12-10-2018 TL08_00785 f1842e87854fa92d1dceac0af2875a70 695 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 49 109 1.4E-10 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TL08_00785 f1842e87854fa92d1dceac0af2875a70 695 SUPERFAMILY SSF56801 50 648 1.44E-122 T 12-10-2018 TL08_00785 f1842e87854fa92d1dceac0af2875a70 695 Gene3D G3DSA:3.30.300.30 544 667 3.5E-7 T 12-10-2018 TL08_08285 d62fcefebc57dee4eebeefdc38c40fce 362 Gene3D G3DSA:3.20.20.70 9 358 6.1E-153 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_08285 d62fcefebc57dee4eebeefdc38c40fce 362 SUPERFAMILY SSF51569 15 356 3.22E-130 T 12-10-2018 TL08_08285 d62fcefebc57dee4eebeefdc38c40fce 362 Pfam PF00793 DAHP synthetase I family 51 345 9.3E-93 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TL08_08285 d62fcefebc57dee4eebeefdc38c40fce 362 PIRSF PIRSF001361 3 360 5.4E-155 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TL08_08285 d62fcefebc57dee4eebeefdc38c40fce 362 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 15 357 5.0E-149 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TL08_19195 8df673ae9c8113866b2d9da2c52390ac 215 SUPERFAMILY SSF100950 4 213 4.51E-75 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_19195 8df673ae9c8113866b2d9da2c52390ac 215 Pfam PF01144 Coenzyme A transferase 6 200 3.2E-45 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 TL08_19195 8df673ae9c8113866b2d9da2c52390ac 215 SMART SM00882 6 202 4.6E-78 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 TL08_19195 8df673ae9c8113866b2d9da2c52390ac 215 Gene3D G3DSA:3.40.1080.10 1 214 7.5E-106 T 12-10-2018 TL08_19195 8df673ae9c8113866b2d9da2c52390ac 215 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 4.5E-100 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 TL08_25185 a99fe8aa68869298dfd697ca185a31d5 498 PIRSF PIRSF012666 1 498 1.0E-209 T 12-10-2018 IPR016602 Uncharacterised conserved protein UCP012666 TL08_25185 a99fe8aa68869298dfd697ca185a31d5 498 SUPERFAMILY SSF55931 38 462 1.47E-51 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TL08_25185 a99fe8aa68869298dfd697ca185a31d5 498 Gene3D G3DSA:3.30.590.20 39 470 7.4E-58 T 12-10-2018 TL08_13665 b43d147961287de8648d25ad960487c1 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 273 6.5E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_13665 b43d147961287de8648d25ad960487c1 284 Gene3D G3DSA:1.10.3720.10 11 275 1.5E-57 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13665 b43d147961287de8648d25ad960487c1 284 SUPERFAMILY SSF161098 22 284 2.71E-65 T 12-10-2018 IPR035906 MetI-like superfamily TL08_10590 f19cb60a39f9318084d87e46fe707651 451 Pfam PF00202 Aminotransferase class-III 36 447 1.1E-77 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_10590 f19cb60a39f9318084d87e46fe707651 451 Gene3D G3DSA:3.40.640.10 71 354 2.1E-137 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_10590 f19cb60a39f9318084d87e46fe707651 451 SUPERFAMILY SSF53383 30 449 1.94E-82 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_10590 f19cb60a39f9318084d87e46fe707651 451 PIRSF PIRSF000521 4 450 7.7E-149 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_10590 f19cb60a39f9318084d87e46fe707651 451 Gene3D G3DSA:3.90.1150.10 40 443 2.1E-137 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_10590 f19cb60a39f9318084d87e46fe707651 451 TIGRFAM TIGR03251 LAT_fam: L-lysine 6-transaminase 16 447 5.6E-210 T 12-10-2018 IPR017657 L-lysine 6-transaminase GO:0017000|GO:0030170|GO:0045484 MetaCyc: PWY-5298 TL08_01635 3e458b667340cafd0e145cd81277ee6a 606 Pfam PF07690 Major Facilitator Superfamily 31 429 5.7E-49 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_01635 3e458b667340cafd0e145cd81277ee6a 606 SUPERFAMILY SSF103473 20 536 5.1E-64 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_01635 3e458b667340cafd0e145cd81277ee6a 606 Gene3D G3DSA:1.20.1720.10 28 236 2.0E-49 T 12-10-2018 TL08_01635 3e458b667340cafd0e145cd81277ee6a 606 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 535 1.6E-72 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TL08_23515 f4f6d7790f6814c9b96469cc959c9ad4 396 Pfam PF01139 tRNA-splicing ligase RtcB 28 396 2.0E-127 T 12-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TL08_23515 f4f6d7790f6814c9b96469cc959c9ad4 396 Gene3D G3DSA:3.90.1860.10 3 396 4.3E-114 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TL08_23515 f4f6d7790f6814c9b96469cc959c9ad4 396 SUPERFAMILY SSF103365 9 396 2.35E-129 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TL08_06990 37a20dca63ab4d0b15ab35a5964dccff 563 Pfam PF00501 AMP-binding enzyme 55 442 5.6E-57 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_06990 37a20dca63ab4d0b15ab35a5964dccff 563 SUPERFAMILY SSF56801 43 444 1.02E-67 T 12-10-2018 TL08_06990 37a20dca63ab4d0b15ab35a5964dccff 563 Gene3D G3DSA:3.40.50.12780 45 439 2.2E-71 T 12-10-2018 TL08_18925 6e38fc5f5a17dbd9072d8c91619f9479 535 SUPERFAMILY SSF49785 387 533 9.92E-6 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_18925 6e38fc5f5a17dbd9072d8c91619f9479 535 Gene3D G3DSA:2.60.120.260 388 533 3.7E-14 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_18925 6e38fc5f5a17dbd9072d8c91619f9479 535 Pfam PF13810 Domain of unknown function (DUF4185) 77 379 1.2E-102 T 12-10-2018 IPR025442 Domain of unknown function DUF4185 TL08_09485 5aa64b5f71785209f30cf36da6e7ddb6 402 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 47 400 30.275 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_09485 5aa64b5f71785209f30cf36da6e7ddb6 402 Gene3D G3DSA:3.40.50.2000 203 384 1.1E-93 T 12-10-2018 TL08_09485 5aa64b5f71785209f30cf36da6e7ddb6 402 SUPERFAMILY SSF53756 47 400 1.35E-94 T 12-10-2018 TL08_09485 5aa64b5f71785209f30cf36da6e7ddb6 402 Gene3D G3DSA:3.40.50.2000 48 390 1.1E-93 T 12-10-2018 TL08_09485 5aa64b5f71785209f30cf36da6e7ddb6 402 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 46 395 5.3E-83 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_09485 5aa64b5f71785209f30cf36da6e7ddb6 402 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 47 185 7.8E-36 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_09485 5aa64b5f71785209f30cf36da6e7ddb6 402 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 231 391 7.0E-38 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TL08_25060 d58ebdffbbd0a39eb8d7e585862e29e5 945 Pfam PF01580 FtsK/SpoIIIE family 395 594 1.8E-19 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TL08_25060 d58ebdffbbd0a39eb8d7e585862e29e5 945 Gene3D G3DSA:3.40.50.300 135 368 6.7E-6 T 12-10-2018 TL08_25060 d58ebdffbbd0a39eb8d7e585862e29e5 945 Gene3D G3DSA:3.40.50.300 372 643 1.3E-51 T 12-10-2018 TL08_25060 d58ebdffbbd0a39eb8d7e585862e29e5 945 SUPERFAMILY SSF52540 378 597 7.86E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06975 c65279532955bad569c2d9101daadfc2 217 SMART SM00479 4 179 1.7E-31 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_06975 c65279532955bad569c2d9101daadfc2 217 Hamap MF_00045 Oligoribonuclease [orn]. 1 180 38.695 T 12-10-2018 IPR022894 Oligoribonuclease GO:0000175 TL08_06975 c65279532955bad569c2d9101daadfc2 217 SUPERFAMILY SSF53098 3 178 1.66E-45 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_06975 c65279532955bad569c2d9101daadfc2 217 Pfam PF00929 Exonuclease 6 169 6.6E-32 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_06975 c65279532955bad569c2d9101daadfc2 217 Gene3D G3DSA:3.30.420.10 1 182 7.0E-72 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_19545 dbf9fe87962dc29372f28a15b7e6803b 418 Gene3D G3DSA:3.40.50.2000 17 400 2.0E-124 T 12-10-2018 TL08_19545 dbf9fe87962dc29372f28a15b7e6803b 418 Pfam PF13439 Glycosyltransferase Family 4 33 209 1.1E-34 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_19545 dbf9fe87962dc29372f28a15b7e6803b 418 SUPERFAMILY SSF53756 14 401 3.93E-93 T 12-10-2018 TL08_19545 dbf9fe87962dc29372f28a15b7e6803b 418 Gene3D G3DSA:3.40.50.2000 205 383 2.0E-124 T 12-10-2018 TL08_19545 dbf9fe87962dc29372f28a15b7e6803b 418 Pfam PF00534 Glycosyl transferases group 1 224 382 1.6E-39 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 SMART SM00347 31 131 3.8E-24 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 Gene3D G3DSA:1.10.10.10 4 152 3.6E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 SUPERFAMILY SSF46785 21 146 1.34E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 SUPERFAMILY SSF56214 202 288 9.94E-11 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 Pfam PF01047 MarR family 38 95 6.7E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 296 357 1.7E-8 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 SUPERFAMILY SSF56214 295 367 1.57E-12 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 Gene3D G3DSA:3.90.470.20 200 315 2.5E-21 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 104 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 4.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 4.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 4.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_17625 8d8a3104b7e154a04c77ae58b896be6a 428 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 4.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_18025 b470917e1c24673584fdb1834d0746b1 342 Pfam PF11382 Copper transport outer membrane protein, MctB 1 306 2.3E-80 T 12-10-2018 IPR021522 Copper transporter MctB GO:0016020|GO:0055070 TL08_02525 d9cee40b906583646b40b7f8d3cbb5a1 287 Pfam PF00378 Enoyl-CoA hydratase/isomerase 29 282 2.1E-78 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TL08_02525 d9cee40b906583646b40b7f8d3cbb5a1 287 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 15 286 53.864 T 12-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 TL08_02525 d9cee40b906583646b40b7f8d3cbb5a1 287 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 125 145 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TL08_02525 d9cee40b906583646b40b7f8d3cbb5a1 287 SUPERFAMILY SSF52096 15 282 5.12E-77 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_02525 d9cee40b906583646b40b7f8d3cbb5a1 287 TIGRFAM TIGR01929 menB: naphthoate synthase 21 283 1.9E-129 T 12-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 TL08_02525 d9cee40b906583646b40b7f8d3cbb5a1 287 Gene3D G3DSA:3.90.226.10 6 224 2.0E-71 T 12-10-2018 TL08_02525 d9cee40b906583646b40b7f8d3cbb5a1 287 Gene3D G3DSA:1.10.12.10 225 275 2.3E-25 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TL08_04980 82f40ec6ca25c8699a29229b6a629a87 142 SUPERFAMILY SSF46955 1 117 1.17E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_04980 82f40ec6ca25c8699a29229b6a629a87 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.6E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_04980 82f40ec6ca25c8699a29229b6a629a87 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.6E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_04980 82f40ec6ca25c8699a29229b6a629a87 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.6E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_04980 82f40ec6ca25c8699a29229b6a629a87 142 Pfam PF13411 MerR HTH family regulatory protein 1 67 4.1E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_04980 82f40ec6ca25c8699a29229b6a629a87 142 SMART SM00422 1 69 3.8E-22 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_04980 82f40ec6ca25c8699a29229b6a629a87 142 Gene3D G3DSA:1.10.1660.10 1 133 9.0E-28 T 12-10-2018 TL08_25825 62bceb7552dddb228d0c378d83aed56a 328 PIRSF PIRSF017082 3 328 3.1E-96 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TL08_25825 62bceb7552dddb228d0c378d83aed56a 328 SUPERFAMILY SSF53850 93 293 2.99E-11 T 12-10-2018 TL08_25825 62bceb7552dddb228d0c378d83aed56a 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 74 328 5.5E-35 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TL08_25825 62bceb7552dddb228d0c378d83aed56a 328 Gene3D G3DSA:3.40.190.150 39 321 1.4E-72 T 12-10-2018 TL08_25825 62bceb7552dddb228d0c378d83aed56a 328 Gene3D G3DSA:3.40.190.10 132 256 1.4E-72 T 12-10-2018 TL08_10480 1fcb59cf330bd0a6d16d7afd7f88104e 155 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 130 2.2E-10 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 TL08_10480 1fcb59cf330bd0a6d16d7afd7f88104e 155 Gene3D G3DSA:3.30.530.20 1 153 3.8E-45 T 12-10-2018 IPR023393 START-like domain superfamily TL08_10480 1fcb59cf330bd0a6d16d7afd7f88104e 155 SUPERFAMILY SSF55961 3 149 3.78E-35 T 12-10-2018 TL08_02275 eb451a8bdd441ba7f0f59b989ea63450 493 Pfam PF07690 Major Facilitator Superfamily 27 417 9.6E-52 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_02275 eb451a8bdd441ba7f0f59b989ea63450 493 SUPERFAMILY SSF103473 16 472 3.14E-73 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_02275 eb451a8bdd441ba7f0f59b989ea63450 493 Gene3D G3DSA:1.20.1720.10 22 231 1.3E-52 T 12-10-2018 TL08_02275 eb451a8bdd441ba7f0f59b989ea63450 493 Gene3D G3DSA:1.20.1250.20 267 473 4.6E-20 T 12-10-2018 TL08_02275 eb451a8bdd441ba7f0f59b989ea63450 493 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 409 8.3E-73 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TL08_02860 2317c345d6a5303d254653975ad98645 141 PRINTS PR01483 Fatty acid synthase signature 24 46 5.2E-7 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 TL08_02860 2317c345d6a5303d254653975ad98645 141 PRINTS PR01483 Fatty acid synthase signature 46 67 5.2E-7 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 TL08_02860 2317c345d6a5303d254653975ad98645 141 Gene3D G3DSA:3.10.129.10 1 141 1.5E-45 T 12-10-2018 TL08_02860 2317c345d6a5303d254653975ad98645 141 SUPERFAMILY SSF54637 8 131 1.32E-29 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_02860 2317c345d6a5303d254653975ad98645 141 Pfam PF01575 MaoC like domain 17 122 9.6E-26 T 12-10-2018 IPR002539 MaoC-like dehydratase domain TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 SUPERFAMILY SSF53335 171 476 5.68E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 SUPERFAMILY SSF48013 32 186 2.45E-31 T 12-10-2018 IPR035926 NusB-like superfamily TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 358 370 3.7E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 408 424 3.7E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 294 304 3.7E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 459 476 3.7E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 261 275 3.7E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 Gene3D G3DSA:1.10.940.10 29 169 2.9E-38 T 12-10-2018 IPR035926 NusB-like superfamily TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 Gene3D G3DSA:3.40.50.150 182 476 3.0E-52 T 12-10-2018 TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 357 368 - T 12-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 Pfam PF01189 16S rRNA methyltransferase RsmB/F 292 474 4.2E-43 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TL08_11560 07a195a7ddf832f85d5452e98ca4756d 477 Pfam PF01029 NusB family 32 153 2.1E-24 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TL08_16330 5682c3035396e1d51d62ad0d585b9e04 334 Gene3D G3DSA:3.40.50.150 161 334 3.1E-43 T 12-10-2018 TL08_16330 5682c3035396e1d51d62ad0d585b9e04 334 Gene3D G3DSA:1.10.10.10 5 103 6.2E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16330 5682c3035396e1d51d62ad0d585b9e04 334 Pfam PF13649 Methyltransferase domain 162 256 7.9E-9 T 12-10-2018 TL08_16330 5682c3035396e1d51d62ad0d585b9e04 334 SUPERFAMILY SSF53335 149 322 3.65E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_26895 30cf10db74df8ccb7fd91e4999cfd6b9 343 Pfam PF13411 MerR HTH family regulatory protein 10 78 1.3E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26895 30cf10db74df8ccb7fd91e4999cfd6b9 343 SMART SM00422 10 79 1.8E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26895 30cf10db74df8ccb7fd91e4999cfd6b9 343 SUPERFAMILY SSF46955 10 117 4.03E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_26895 30cf10db74df8ccb7fd91e4999cfd6b9 343 Gene3D G3DSA:1.10.1660.10 4 124 2.2E-24 T 12-10-2018 TL08_26895 30cf10db74df8ccb7fd91e4999cfd6b9 343 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 1.3E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26895 30cf10db74df8ccb7fd91e4999cfd6b9 343 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 1.3E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26895 30cf10db74df8ccb7fd91e4999cfd6b9 343 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 1.3E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_05290 87d273cd29d80e901e4da9251da1a327 421 SUPERFAMILY SSF51905 22 403 4.02E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05290 87d273cd29d80e901e4da9251da1a327 421 Gene3D G3DSA:3.50.50.60 23 402 1.9E-70 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05290 87d273cd29d80e901e4da9251da1a327 421 Gene3D G3DSA:3.30.9.10 101 342 1.9E-70 T 12-10-2018 TL08_05290 87d273cd29d80e901e4da9251da1a327 421 Pfam PF01266 FAD dependent oxidoreductase 23 381 1.2E-46 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_05600 df612a77f8d5b6937eee484b39fe0385 580 Pfam PF00005 ABC transporter 319 460 3.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05600 df612a77f8d5b6937eee484b39fe0385 580 ProSitePatterns PS00211 ABC transporters family signature. 432 446 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_05600 df612a77f8d5b6937eee484b39fe0385 580 SUPERFAMILY SSF52540 4 233 1.08E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05600 df612a77f8d5b6937eee484b39fe0385 580 Gene3D G3DSA:3.40.50.300 2 251 2.2E-60 T 12-10-2018 TL08_05600 df612a77f8d5b6937eee484b39fe0385 580 SMART SM00382 325 508 3.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_05600 df612a77f8d5b6937eee484b39fe0385 580 SMART SM00382 31 220 3.8E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_05600 df612a77f8d5b6937eee484b39fe0385 580 SUPERFAMILY SSF52540 306 528 4.46E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05600 df612a77f8d5b6937eee484b39fe0385 580 Pfam PF00005 ABC transporter 22 171 1.1E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05600 df612a77f8d5b6937eee484b39fe0385 580 Gene3D G3DSA:3.40.50.300 298 549 1.8E-60 T 12-10-2018 TL08_27155 6c5ba35a758df3c476a36066845132cd 45 Pfam PF00468 Ribosomal protein L34 3 45 8.9E-20 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_27155 6c5ba35a758df3c476a36066845132cd 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.811 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_27155 6c5ba35a758df3c476a36066845132cd 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 43 6.0E-13 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_27155 6c5ba35a758df3c476a36066845132cd 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 3.8E-19 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_27155 6c5ba35a758df3c476a36066845132cd 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 12-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_15595 e85fc0be7661307eac8f5a1fe14f93a1 383 SUPERFAMILY SSF81345 40 375 2.35E-73 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_15595 e85fc0be7661307eac8f5a1fe14f93a1 383 Gene3D G3DSA:1.10.3470.10 41 380 3.8E-93 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_15595 e85fc0be7661307eac8f5a1fe14f93a1 383 Pfam PF01032 FecCD transport family 56 375 3.9E-89 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_20600 19ffe6da4bf281da4e2e9535df06b1e3 242 Pfam PF13411 MerR HTH family regulatory protein 3 69 7.5E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_20600 19ffe6da4bf281da4e2e9535df06b1e3 242 SMART SM00422 2 71 1.2E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_20600 19ffe6da4bf281da4e2e9535df06b1e3 242 SUPERFAMILY SSF46955 2 105 1.21E-18 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_22220 cd444fb7024df49b61ee638b01e34c7e 89 Gene3D G3DSA:1.10.1200.10 12 89 2.1E-24 T 12-10-2018 IPR036736 ACP-like superfamily TL08_22220 cd444fb7024df49b61ee638b01e34c7e 89 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 52 85 1.0E-9 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TL08_22220 cd444fb7024df49b61ee638b01e34c7e 89 SUPERFAMILY SSF47336 15 88 2.75E-21 T 12-10-2018 IPR036736 ACP-like superfamily TL08_22220 cd444fb7024df49b61ee638b01e34c7e 89 Hamap MF_01217 Acyl carrier protein [acpP]. 15 89 17.816 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TL08_22220 cd444fb7024df49b61ee638b01e34c7e 89 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 15 89 1.5E-20 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TL08_22220 cd444fb7024df49b61ee638b01e34c7e 89 Pfam PF00550 Phosphopantetheine attachment site 20 85 1.6E-16 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_08825 2e4b5524ae343d121216a9e00ef8a07f 343 SUPERFAMILY SSF52540 7 251 2.31E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08825 2e4b5524ae343d121216a9e00ef8a07f 343 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_08825 2e4b5524ae343d121216a9e00ef8a07f 343 Gene3D G3DSA:3.40.50.300 1 341 4.3E-85 T 12-10-2018 TL08_08825 2e4b5524ae343d121216a9e00ef8a07f 343 SMART SM00382 36 230 1.5E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08825 2e4b5524ae343d121216a9e00ef8a07f 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 317 7.5E-13 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_08825 2e4b5524ae343d121216a9e00ef8a07f 343 Pfam PF00005 ABC transporter 28 180 1.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_03765 0f54263d2b81c3d594ac07f7ad50da24 125 Gene3D G3DSA:1.25.40.10 64 123 7.2E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03765 0f54263d2b81c3d594ac07f7ad50da24 125 SUPERFAMILY SSF48452 8 108 4.05E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03765 0f54263d2b81c3d594ac07f7ad50da24 125 Pfam PF14559 Tetratricopeptide repeat 55 114 3.7E-8 T 12-10-2018 TL08_03765 0f54263d2b81c3d594ac07f7ad50da24 125 SMART SM00028 74 107 17.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03765 0f54263d2b81c3d594ac07f7ad50da24 125 SMART SM00028 40 73 3.8 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_03765 0f54263d2b81c3d594ac07f7ad50da24 125 Gene3D G3DSA:1.25.40.10 8 63 7.9E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05945 6f709ba3f7891c1615a9fcc7a51c9c05 344 Pfam PF13353 4Fe-4S single cluster domain 19 102 2.8E-5 T 12-10-2018 TL08_05945 6f709ba3f7891c1615a9fcc7a51c9c05 344 Gene3D G3DSA:3.20.20.70 17 279 8.7E-18 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_05945 6f709ba3f7891c1615a9fcc7a51c9c05 344 Pfam PF04055 Radical SAM superfamily 24 148 2.3E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_05945 6f709ba3f7891c1615a9fcc7a51c9c05 344 SUPERFAMILY SSF102114 20 267 1.83E-21 T 12-10-2018 TL08_07035 e1211a96fb744d653c02b13ea565fa72 425 SUPERFAMILY SSF53850 33 423 6.92E-49 T 12-10-2018 TL08_07035 e1211a96fb744d653c02b13ea565fa72 425 Gene3D G3DSA:3.40.190.10 52 353 1.8E-65 T 12-10-2018 TL08_07035 e1211a96fb744d653c02b13ea565fa72 425 Pfam PF13416 Bacterial extracellular solute-binding protein 52 355 6.9E-28 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_07035 e1211a96fb744d653c02b13ea565fa72 425 Gene3D G3DSA:3.40.190.10 147 413 1.8E-65 T 12-10-2018 TL08_19075 5238de21f2ef3be109ca01919ebdfef1 410 Gene3D G3DSA:2.130.10.10 17 277 9.8E-9 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_19075 5238de21f2ef3be109ca01919ebdfef1 410 SUPERFAMILY SSF50969 68 405 4.63E-22 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like TL08_19075 5238de21f2ef3be109ca01919ebdfef1 410 Gene3D G3DSA:2.130.10.10 284 407 2.9E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_25960 3d0411d7ae0b3a18d80cab915aaa364b 378 Gene3D G3DSA:3.30.1360.120 28 353 1.7E-62 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TL08_25960 3d0411d7ae0b3a18d80cab915aaa364b 378 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 228 291 5.1E-18 T 12-10-2018 IPR017703 YgfZ/GcvT conserved site TL08_25960 3d0411d7ae0b3a18d80cab915aaa364b 378 Pfam PF01571 Aminomethyltransferase folate-binding domain 26 255 1.0E-25 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TL08_25960 3d0411d7ae0b3a18d80cab915aaa364b 378 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 265 350 3.5E-7 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TL08_25960 3d0411d7ae0b3a18d80cab915aaa364b 378 PIRSF PIRSF006487 20 354 2.9E-19 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TL08_25960 3d0411d7ae0b3a18d80cab915aaa364b 378 SUPERFAMILY SSF103025 27 280 5.49E-55 T 12-10-2018 TL08_23480 7b4ef67a2cbd5860d283d94f7b64b1ea 662 SUPERFAMILY SSF89372 365 623 2.16E-17 T 12-10-2018 TL08_23480 7b4ef67a2cbd5860d283d94f7b64b1ea 662 SUPERFAMILY SSF50934 141 310 3.66E-12 T 12-10-2018 IPR036813 Tachylectin 2 superfamily TL08_23480 7b4ef67a2cbd5860d283d94f7b64b1ea 662 Pfam PF14517 Tachylectin 123 285 1.6E-19 T 12-10-2018 IPR023294 Tachylectin 2 TL08_23480 7b4ef67a2cbd5860d283d94f7b64b1ea 662 Gene3D G3DSA:2.115.10.10 102 325 2.5E-33 T 12-10-2018 TL08_10615 d1fa7e21afeb3529ceec0d1e67d06a84 162 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 42 8.9E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10615 d1fa7e21afeb3529ceec0d1e67d06a84 162 Gene3D G3DSA:1.10.357.10 1 162 1.7E-36 T 12-10-2018 TL08_10615 d1fa7e21afeb3529ceec0d1e67d06a84 162 SUPERFAMILY SSF46689 2 58 4.21E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_10615 d1fa7e21afeb3529ceec0d1e67d06a84 162 SUPERFAMILY SSF48498 69 160 2.11E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 453 2.3E-64 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 Gene3D G3DSA:3.30.420.40 2 255 3.7E-110 T 12-10-2018 TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 SUPERFAMILY SSF53067 257 500 1.07E-82 T 12-10-2018 TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 SUPERFAMILY SSF53067 3 257 2.24E-88 T 12-10-2018 TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 Hamap MF_00186 Glycerol kinase [glpK]. 2 500 55.324 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 499 2.8E-225 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 Gene3D G3DSA:3.30.420.40 256 506 5.6E-94 T 12-10-2018 TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 PIRSF PIRSF000538 2 505 4.4E-167 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TL08_23785 2a81366ef1ff9251993ce2a6b25a36d6 507 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 254 1.2E-74 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TL08_09515 93fe42369414a6dc9877395cc1e5b0a9 205 SUPERFAMILY SSF160467 5 87 6.28E-13 T 12-10-2018 TL08_09515 93fe42369414a6dc9877395cc1e5b0a9 205 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 5 194 3.7E-69 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TL08_09515 93fe42369414a6dc9877395cc1e5b0a9 205 SMART SM00796 4 194 5.4E-90 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TL08_09515 93fe42369414a6dc9877395cc1e5b0a9 205 SUPERFAMILY SSF50891 83 204 2.69E-42 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TL08_09515 93fe42369414a6dc9877395cc1e5b0a9 205 Gene3D G3DSA:2.40.100.10 78 205 1.8E-55 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TL08_09515 93fe42369414a6dc9877395cc1e5b0a9 205 Gene3D G3DSA:3.30.1360.40 2 77 3.7E-19 T 12-10-2018 TL08_13750 58f40d3d5ac78aeecbfb1c92a6621b72 353 SUPERFAMILY SSF56796 9 347 9.55E-82 T 12-10-2018 TL08_13750 58f40d3d5ac78aeecbfb1c92a6621b72 353 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 334 9.2E-74 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TL08_13750 58f40d3d5ac78aeecbfb1c92a6621b72 353 Gene3D G3DSA:3.40.50.1970 1 159 8.7E-44 T 12-10-2018 TL08_13750 58f40d3d5ac78aeecbfb1c92a6621b72 353 Gene3D G3DSA:1.20.1090.10 161 351 3.8E-54 T 12-10-2018 TL08_11970 af763433879a97739244a8f71482e670 281 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 191 280 5.8E-27 T 12-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TL08_11970 af763433879a97739244a8f71482e670 281 Pfam PF01634 ATP phosphoribosyltransferase 49 201 1.4E-39 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TL08_11970 af763433879a97739244a8f71482e670 281 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 TL08_11970 af763433879a97739244a8f71482e670 281 Pfam PF08029 HisG, C-terminal domain 206 276 1.8E-24 T 12-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TL08_11970 af763433879a97739244a8f71482e670 281 Gene3D G3DSA:3.40.190.10 91 178 1.8E-58 T 12-10-2018 TL08_11970 af763433879a97739244a8f71482e670 281 Gene3D G3DSA:3.40.190.10 2 182 1.8E-58 T 12-10-2018 TL08_11970 af763433879a97739244a8f71482e670 281 Gene3D G3DSA:3.30.70.120 209 275 2.0E-26 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TL08_11970 af763433879a97739244a8f71482e670 281 SUPERFAMILY SSF54913 209 280 7.56E-20 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TL08_11970 af763433879a97739244a8f71482e670 281 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 281 30.593 T 12-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 TL08_11970 af763433879a97739244a8f71482e670 281 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 9.8E-51 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TL08_11970 af763433879a97739244a8f71482e670 281 SUPERFAMILY SSF53850 1 206 6.67E-60 T 12-10-2018 TL08_21175 9cc916045916da53d599944f041d68d3 209 SMART SM00421 142 199 1.6E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21175 9cc916045916da53d599944f041d68d3 209 SMART SM00448 2 115 3.9E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_21175 9cc916045916da53d599944f041d68d3 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 199 7.9E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21175 9cc916045916da53d599944f041d68d3 209 Gene3D G3DSA:3.40.50.12740 2 205 4.0E-68 T 12-10-2018 TL08_21175 9cc916045916da53d599944f041d68d3 209 Pfam PF00072 Response regulator receiver domain 5 115 5.0E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_21175 9cc916045916da53d599944f041d68d3 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 2.8E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21175 9cc916045916da53d599944f041d68d3 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 2.8E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21175 9cc916045916da53d599944f041d68d3 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 2.8E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21175 9cc916045916da53d599944f041d68d3 209 SUPERFAMILY SSF46894 134 205 6.12E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_21175 9cc916045916da53d599944f041d68d3 209 SUPERFAMILY SSF52172 1 132 8.82E-34 T 12-10-2018 IPR011006 CheY-like superfamily TL08_13120 a0165aae46b4e910821c0f898a24153a 309 Gene3D G3DSA:3.40.50.10740 5 158 7.6E-46 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal TL08_13120 a0165aae46b4e910821c0f898a24153a 309 SUPERFAMILY SSF141986 154 300 1.57E-35 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily TL08_13120 a0165aae46b4e910821c0f898a24153a 309 Gene3D G3DSA:3.50.30.60 176 301 7.9E-37 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily TL08_13120 a0165aae46b4e910821c0f898a24153a 309 Pfam PF02016 LD-carboxypeptidase 16 294 6.2E-67 T 12-10-2018 IPR003507 Peptidase family S66 TL08_13120 a0165aae46b4e910821c0f898a24153a 309 SUPERFAMILY SSF52317 5 167 1.69E-37 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_13120 a0165aae46b4e910821c0f898a24153a 309 PIRSF PIRSF028757 5 309 8.2E-62 T 12-10-2018 IPR003507 Peptidase family S66 TL08_08000 6e7b643620919b006c5988740fc30fd6 138 PIRSF PIRSF021320 2 138 1.7E-35 T 12-10-2018 IPR009326 Protein of unknown function DUF984 TL08_08000 6e7b643620919b006c5988740fc30fd6 138 Gene3D G3DSA:3.10.400.10 3 138 3.8E-38 T 12-10-2018 TL08_08000 6e7b643620919b006c5988740fc30fd6 138 SMART SM01022 11 137 4.6E-20 T 12-10-2018 IPR007374 ASCH domain TL08_08000 6e7b643620919b006c5988740fc30fd6 138 Pfam PF04266 ASCH domain 21 136 3.1E-14 T 12-10-2018 IPR007374 ASCH domain TL08_08000 6e7b643620919b006c5988740fc30fd6 138 SUPERFAMILY SSF88697 9 137 1.21E-29 T 12-10-2018 IPR015947 PUA-like superfamily TL08_21425 ee311dba50557ddad12a94a1f0b31cd6 235 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 28 234 7.5E-57 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 TL08_21425 ee311dba50557ddad12a94a1f0b31cd6 235 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 47 233 1.9E-71 T 12-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 TL08_21425 ee311dba50557ddad12a94a1f0b31cd6 235 SUPERFAMILY SSF52402 25 199 2.27E-42 T 12-10-2018 TL08_21425 ee311dba50557ddad12a94a1f0b31cd6 235 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 46 210 1.7E-42 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TL08_21425 ee311dba50557ddad12a94a1f0b31cd6 235 Gene3D G3DSA:3.40.50.620 4 235 1.9E-65 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_21425 ee311dba50557ddad12a94a1f0b31cd6 235 PIRSF PIRSF000857 1 235 3.0E-92 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 TL08_03500 284d3d0279f73ef796ae1808adc938ed 284 Gene3D G3DSA:3.40.1010.10 2 118 1.5E-30 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TL08_03500 284d3d0279f73ef796ae1808adc938ed 284 SUPERFAMILY SSF53790 8 227 1.44E-70 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TL08_03500 284d3d0279f73ef796ae1808adc938ed 284 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 9 229 32.712 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TL08_03500 284d3d0279f73ef796ae1808adc938ed 284 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 10 277 3.9E-61 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TL08_03500 284d3d0279f73ef796ae1808adc938ed 284 PIRSF PIRSF005917 1 282 1.4E-89 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TL08_03500 284d3d0279f73ef796ae1808adc938ed 284 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 211 1.7E-27 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TL08_03500 284d3d0279f73ef796ae1808adc938ed 284 Gene3D G3DSA:3.30.950.10 119 236 1.2E-40 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TL08_16110 25752797dda60c132db751aed1de9565 280 Gene3D G3DSA:3.40.50.720 2 277 9.0E-69 T 12-10-2018 TL08_16110 25752797dda60c132db751aed1de9565 280 SUPERFAMILY SSF51735 2 243 6.98E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16110 25752797dda60c132db751aed1de9565 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 5.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16110 25752797dda60c132db751aed1de9565 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 5.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16110 25752797dda60c132db751aed1de9565 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 5.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16110 25752797dda60c132db751aed1de9565 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 6.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16110 25752797dda60c132db751aed1de9565 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 6.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16110 25752797dda60c132db751aed1de9565 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 6.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16110 25752797dda60c132db751aed1de9565 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16110 25752797dda60c132db751aed1de9565 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 6.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16110 25752797dda60c132db751aed1de9565 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 6.1E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16110 25752797dda60c132db751aed1de9565 280 Pfam PF00106 short chain dehydrogenase 4 187 2.9E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18140 bf7420a27da72953ba5553364c7acb7a 173 Pfam PF14534 Domain of unknown function (DUF4440) 21 132 8.6E-9 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 TL08_18140 bf7420a27da72953ba5553364c7acb7a 173 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 17 140 7.2E-24 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 TL08_18140 bf7420a27da72953ba5553364c7acb7a 173 SUPERFAMILY SSF54427 15 143 1.39E-28 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_18140 bf7420a27da72953ba5553364c7acb7a 173 Gene3D G3DSA:3.10.450.50 11 163 3.2E-34 T 12-10-2018 TL08_21385 53699cac1d0d2a0ff2eb1dfe2b2e8f4f 389 Pfam PF02562 PhoH-like protein 156 359 4.1E-94 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 TL08_21385 53699cac1d0d2a0ff2eb1dfe2b2e8f4f 389 Gene3D G3DSA:3.40.50.300 153 359 3.9E-76 T 12-10-2018 TL08_21385 53699cac1d0d2a0ff2eb1dfe2b2e8f4f 389 SUPERFAMILY SSF52540 155 323 5.94E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 PIRSF PIRSF036643 23 608 1.1E-98 T 12-10-2018 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 PIRSF PIRSF036643 622 804 2.7E-24 T 12-10-2018 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 Gene3D G3DSA:3.40.228.10 174 379 4.8E-156 T 12-10-2018 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 Pfam PF01568 Molydopterin dinucleotide binding domain 655 776 3.9E-24 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 SUPERFAMILY SSF50692 627 783 8.82E-38 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 40 85 5.2E-8 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 SMART SM00926 39 95 4.0E-9 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 Gene3D G3DSA:3.40.50.740 101 583 4.8E-156 T 12-10-2018 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 Gene3D G3DSA:2.20.25.90 35 89 4.2E-13 T 12-10-2018 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 Gene3D G3DSA:2.40.40.20 644 786 4.5E-39 T 12-10-2018 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 Pfam PF00384 Molybdopterin oxidoreductase 96 524 6.2E-64 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_19955 0555138bba87baee8de51e36e3eb8d0c 855 SUPERFAMILY SSF53706 40 606 2.22E-162 T 12-10-2018 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 Gene3D G3DSA:3.40.50.1980 62 207 2.6E-34 T 12-10-2018 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 SUPERFAMILY SSF53807 62 339 2.31E-61 T 12-10-2018 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00691 Adhesin B signature 63 84 2.6E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00691 Adhesin B signature 221 238 2.6E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00691 Adhesin B signature 107 126 2.6E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00691 Adhesin B signature 163 182 2.6E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00691 Adhesin B signature 88 106 2.6E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00691 Adhesin B signature 270 287 2.6E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00690 Adhesin family signature 305 324 1.9E-31 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00690 Adhesin family signature 94 107 1.9E-31 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00690 Adhesin family signature 221 242 1.9E-31 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00690 Adhesin family signature 274 292 1.9E-31 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00690 Adhesin family signature 107 124 1.9E-31 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 PRINTS PR00690 Adhesin family signature 63 81 1.9E-31 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 Gene3D G3DSA:3.40.50.1980 210 340 1.2E-39 T 12-10-2018 TL08_10645 de7324d0e683c264ba7928bcb8ea6d59 340 Pfam PF01297 Zinc-uptake complex component A periplasmic 66 336 3.8E-57 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TL08_02345 e11dead399f224d6317bb18ee5285e6e 189 Pfam PF04542 Sigma-70 region 2 27 94 1.0E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_02345 e11dead399f224d6317bb18ee5285e6e 189 SUPERFAMILY SSF88946 6 105 1.57E-26 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_02345 e11dead399f224d6317bb18ee5285e6e 189 Pfam PF04545 Sigma-70, region 4 134 180 6.4E-9 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TL08_02345 e11dead399f224d6317bb18ee5285e6e 189 Gene3D G3DSA:1.10.10.10 129 187 6.4E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_02345 e11dead399f224d6317bb18ee5285e6e 189 SUPERFAMILY SSF88659 109 185 9.91E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_02345 e11dead399f224d6317bb18ee5285e6e 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 181 1.3E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_02345 e11dead399f224d6317bb18ee5285e6e 189 Gene3D G3DSA:1.10.1740.10 3 91 5.0E-24 T 12-10-2018 TL08_12175 20680120d6edad4f793ea88bcdec6b78 517 Gene3D G3DSA:2.30.40.10 1 457 2.9E-91 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_12175 20680120d6edad4f793ea88bcdec6b78 517 Pfam PF07969 Amidohydrolase family 27 506 3.4E-89 T 12-10-2018 IPR013108 Amidohydrolase 3 TL08_12175 20680120d6edad4f793ea88bcdec6b78 517 Gene3D G3DSA:3.20.20.140 38 444 2.9E-91 T 12-10-2018 TL08_12175 20680120d6edad4f793ea88bcdec6b78 517 Gene3D G3DSA:3.10.310.70 56 164 2.9E-91 T 12-10-2018 TL08_12175 20680120d6edad4f793ea88bcdec6b78 517 SUPERFAMILY SSF51556 37 441 2.0E-31 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_12175 20680120d6edad4f793ea88bcdec6b78 517 SUPERFAMILY SSF51338 2 462 1.47E-6 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_25570 e51c4f95bff03cceea6f1fbb838a3a27 167 Gene3D G3DSA:1.10.1740.10 2 95 3.7E-16 T 12-10-2018 TL08_25570 e51c4f95bff03cceea6f1fbb838a3a27 167 Gene3D G3DSA:1.10.10.10 96 157 5.3E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25570 e51c4f95bff03cceea6f1fbb838a3a27 167 SUPERFAMILY SSF88659 94 158 8.22E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_25570 e51c4f95bff03cceea6f1fbb838a3a27 167 Pfam PF04542 Sigma-70 region 2 10 73 9.7E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_25570 e51c4f95bff03cceea6f1fbb838a3a27 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 154 3.7E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_25570 e51c4f95bff03cceea6f1fbb838a3a27 167 SUPERFAMILY SSF88946 4 88 1.77E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_25570 e51c4f95bff03cceea6f1fbb838a3a27 167 Pfam PF08281 Sigma-70, region 4 101 151 2.9E-9 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_07665 c26814ef5879600c529946be4822ae87 302 SUPERFAMILY SSF53474 21 298 1.55E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07665 c26814ef5879600c529946be4822ae87 302 Pfam PF12697 Alpha/beta hydrolase family 26 287 6.2E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_07665 c26814ef5879600c529946be4822ae87 302 Gene3D G3DSA:3.40.50.1820 20 300 1.3E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_01735 4b1b230797c15aec4850bdbae8aca9b6 116 Gene3D G3DSA:3.30.60.230 1 60 2.2E-25 T 12-10-2018 TL08_01735 4b1b230797c15aec4850bdbae8aca9b6 116 Pfam PF11774 Lsr2 1 115 2.7E-42 T 12-10-2018 IPR024412 Lsr2 TL08_01735 4b1b230797c15aec4850bdbae8aca9b6 116 Gene3D G3DSA:1.20.890.50 82 116 5.0E-18 T 12-10-2018 TL08_01735 4b1b230797c15aec4850bdbae8aca9b6 116 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 113 2.0E-27 T 12-10-2018 IPR024412 Lsr2 TL08_21040 0836da339cb1109d57afe98866b94ec7 504 Pfam PF13148 Protein of unknown function (DUF3987) 46 407 1.0E-97 T 12-10-2018 IPR025048 Protein of unknown function DUF3987) TL08_14090 0f10129cc335b1d30252d555d21d984d 125 SUPERFAMILY SSF54593 11 121 8.06E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_14090 0f10129cc335b1d30252d555d21d984d 125 Gene3D G3DSA:3.10.180.10 2 124 1.4E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_14090 0f10129cc335b1d30252d555d21d984d 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 119 3.7E-5 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_14405 cfe672151879eb0acf89d215f44e1749 440 Pfam PF00425 chorismate binding enzyme 177 429 4.9E-65 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TL08_14405 cfe672151879eb0acf89d215f44e1749 440 TIGRFAM TIGR03494 salicyl_syn: salicylate synthase 22 438 3.9E-147 T 12-10-2018 IPR019996 Salicylate synthase GO:0008909|GO:0016833 KEGG: 00130+5.4.4.2|KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TL08_14405 cfe672151879eb0acf89d215f44e1749 440 SUPERFAMILY SSF56322 8 437 7.33E-89 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TL08_14405 cfe672151879eb0acf89d215f44e1749 440 Gene3D G3DSA:3.60.120.10 2 440 8.0E-133 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TL08_14405 cfe672151879eb0acf89d215f44e1749 440 PRINTS PR00095 Anthranilate synthase component I signature 371 385 1.5E-5 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_14405 cfe672151879eb0acf89d215f44e1749 440 PRINTS PR00095 Anthranilate synthase component I signature 278 291 1.5E-5 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_14405 cfe672151879eb0acf89d215f44e1749 440 PRINTS PR00095 Anthranilate synthase component I signature 386 400 1.5E-5 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_12500 050fa3781357518c0bd072171568b81c 280 PRINTS PR00412 Epoxide hydrolase signature 39 57 7.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_12500 050fa3781357518c0bd072171568b81c 280 PRINTS PR00412 Epoxide hydrolase signature 59 74 7.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_12500 050fa3781357518c0bd072171568b81c 280 PRINTS PR00412 Epoxide hydrolase signature 251 273 7.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_12500 050fa3781357518c0bd072171568b81c 280 PRINTS PR00412 Epoxide hydrolase signature 218 234 7.2E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_12500 050fa3781357518c0bd072171568b81c 280 Pfam PF00561 alpha/beta hydrolase fold 34 263 3.9E-29 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_12500 050fa3781357518c0bd072171568b81c 280 Gene3D G3DSA:3.40.50.1820 8 276 1.7E-79 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_12500 050fa3781357518c0bd072171568b81c 280 SUPERFAMILY SSF53474 13 272 1.5E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_12500 050fa3781357518c0bd072171568b81c 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 220 234 2.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_12500 050fa3781357518c0bd072171568b81c 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 2.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_12500 050fa3781357518c0bd072171568b81c 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 2.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_12500 050fa3781357518c0bd072171568b81c 280 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 2.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_01440 4ffaab105e5c7914b7d737df8d61d49f 253 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 55 179 1.5E-17 T 12-10-2018 TL08_01440 4ffaab105e5c7914b7d737df8d61d49f 253 SUPERFAMILY SSF56784 42 199 1.54E-24 T 12-10-2018 IPR036412 HAD-like superfamily TL08_01440 4ffaab105e5c7914b7d737df8d61d49f 253 Gene3D G3DSA:1.20.1440.100 4 78 9.2E-58 T 12-10-2018 TL08_01440 4ffaab105e5c7914b7d737df8d61d49f 253 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 177 5.6E-26 T 12-10-2018 TL08_01440 4ffaab105e5c7914b7d737df8d61d49f 253 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 2 190 4.5E-56 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like TL08_01440 4ffaab105e5c7914b7d737df8d61d49f 253 Gene3D G3DSA:3.40.50.1000 2 202 9.2E-58 T 12-10-2018 IPR023214 HAD superfamily TL08_07075 e683b358f36411b0a41ceccbb88ec692 250 SUPERFAMILY SSF53955 46 250 1.12E-65 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_07075 e683b358f36411b0a41ceccbb88ec692 250 Gene3D G3DSA:1.10.530.70 46 241 2.0E-81 T 12-10-2018 TL08_07075 e683b358f36411b0a41ceccbb88ec692 250 PIRSF PIRSF001060 6 250 8.0E-80 T 12-10-2018 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 TL08_07075 e683b358f36411b0a41ceccbb88ec692 250 Pfam PF00182 Chitinase class I 48 250 3.1E-43 T 12-10-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 TL08_21790 c44192badfec69cb1d7cad1520c591b7 642 Gene3D G3DSA:3.60.20.10 4 192 6.7E-54 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_21790 c44192badfec69cb1d7cad1520c591b7 642 SUPERFAMILY SSF52402 249 617 2.07E-83 T 12-10-2018 TL08_21790 c44192badfec69cb1d7cad1520c591b7 642 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 559 7.1E-141 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TL08_21790 c44192badfec69cb1d7cad1520c591b7 642 Pfam PF13537 Glutamine amidotransferase domain 50 172 4.0E-36 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TL08_21790 c44192badfec69cb1d7cad1520c591b7 642 PIRSF PIRSF001589 1 635 6.8E-170 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TL08_21790 c44192badfec69cb1d7cad1520c591b7 642 Pfam PF00733 Asparagine synthase 253 621 2.5E-102 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TL08_21790 c44192badfec69cb1d7cad1520c591b7 642 SUPERFAMILY SSF56235 2 230 7.55E-53 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_13370 6cb7775b991b705640a03c7aaac0ccfb 459 Gene3D G3DSA:3.90.1150.160 358 459 7.9E-30 T 12-10-2018 TL08_13370 6cb7775b991b705640a03c7aaac0ccfb 459 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 34 441 5.3E-181 T 12-10-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 TL08_13370 6cb7775b991b705640a03c7aaac0ccfb 459 Gene3D G3DSA:3.40.640.10 73 356 7.4E-78 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_13370 6cb7775b991b705640a03c7aaac0ccfb 459 SUPERFAMILY SSF53383 31 443 3.28E-124 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_13370 6cb7775b991b705640a03c7aaac0ccfb 459 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 55 369 9.0E-65 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 TL08_21010 8241f1cd6b756228a98f3412b2134d28 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.6E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_21010 8241f1cd6b756228a98f3412b2134d28 228 SUPERFAMILY SSF46689 9 76 1.85E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_21010 8241f1cd6b756228a98f3412b2134d28 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_21010 8241f1cd6b756228a98f3412b2134d28 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_21010 8241f1cd6b756228a98f3412b2134d28 228 SUPERFAMILY SSF48498 89 190 1.2E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_21010 8241f1cd6b756228a98f3412b2134d28 228 Gene3D G3DSA:1.10.357.10 8 194 1.6E-28 T 12-10-2018 TL08_25830 652cc8ce6f530725ecebcda488ed921c 276 Pfam PF01614 Bacterial transcriptional regulator 145 262 1.1E-20 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_25830 652cc8ce6f530725ecebcda488ed921c 276 SUPERFAMILY SSF55781 103 263 1.05E-35 T 12-10-2018 TL08_25830 652cc8ce6f530725ecebcda488ed921c 276 SMART SM00346 28 117 1.6E-6 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_25830 652cc8ce6f530725ecebcda488ed921c 276 Pfam PF09339 IclR helix-turn-helix domain 30 77 8.0E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_25830 652cc8ce6f530725ecebcda488ed921c 276 SUPERFAMILY SSF46785 28 99 2.01E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_25830 652cc8ce6f530725ecebcda488ed921c 276 Gene3D G3DSA:1.10.10.10 11 88 1.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25830 652cc8ce6f530725ecebcda488ed921c 276 Gene3D G3DSA:3.30.450.40 93 268 1.3E-53 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_12665 ee694f422a8532cb5bc1159440139509 276 Gene3D G3DSA:1.10.3720.10 76 270 4.8E-29 T 12-10-2018 IPR035906 MetI-like superfamily TL08_12665 ee694f422a8532cb5bc1159440139509 276 SUPERFAMILY SSF161098 76 261 6.02E-36 T 12-10-2018 IPR035906 MetI-like superfamily TL08_12665 ee694f422a8532cb5bc1159440139509 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 269 8.3E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_08850 d2e6d8854384cc457a3d72556f68f46c 383 SUPERFAMILY SSF102405 107 300 2.59E-33 T 12-10-2018 TL08_08850 d2e6d8854384cc457a3d72556f68f46c 383 Pfam PF02481 DNA recombination-mediator protein A 72 290 8.7E-69 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TL08_08850 d2e6d8854384cc457a3d72556f68f46c 383 Gene3D G3DSA:3.40.50.450 2 303 1.9E-87 T 12-10-2018 TL08_08850 d2e6d8854384cc457a3d72556f68f46c 383 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 69 297 5.9E-64 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TL08_19260 d5822ca9bec597c4e7d13c4923e17a0f 128 Pfam PF00929 Exonuclease 10 125 3.5E-15 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_19260 d5822ca9bec597c4e7d13c4923e17a0f 128 SMART SM00479 8 128 8.8E-10 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_19260 d5822ca9bec597c4e7d13c4923e17a0f 128 Gene3D G3DSA:3.30.420.10 2 128 3.7E-29 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_19260 d5822ca9bec597c4e7d13c4923e17a0f 128 SUPERFAMILY SSF53098 4 123 1.64E-26 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SUPERFAMILY SSF47336 1763 1850 2.26E-8 T 12-10-2018 IPR036736 ACP-like superfamily TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 665 929 2.1E-67 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 937 1054 3.5E-36 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Pfam PF00698 Acyl transferase domain 1247 1527 2.5E-29 T 12-10-2018 IPR014043 Acyl transferase TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Gene3D G3DSA:3.30.70.250 1369 1439 4.6E-73 T 12-10-2018 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SUPERFAMILY SSF51412 18 186 3.89E-12 T 12-10-2018 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SUPERFAMILY SSF51412 297 522 8.85E-15 T 12-10-2018 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Gene3D G3DSA:3.40.50.720 1891 2373 9.7E-71 T 12-10-2018 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SMART SM00825 Beta-ketoacyl synthase 666 1107 4.7E-95 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1247 1547 3.1E-32 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Pfam PF03060 Nitronate monooxygenase 372 632 1.5E-12 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SUPERFAMILY SSF53901 660 1053 3.04E-72 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Gene3D G3DSA:3.20.20.70 13 290 1.4E-27 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Gene3D G3DSA:3.20.20.70 293 654 5.9E-69 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Gene3D G3DSA:1.10.1200.10 1749 1849 2.9E-19 T 12-10-2018 IPR036736 ACP-like superfamily TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SUPERFAMILY SSF55048 1373 1437 3.66E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SUPERFAMILY SSF52151 1244 1542 1.91E-53 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Pfam PF08659 KR domain 2102 2323 2.3E-29 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Gene3D G3DSA:3.40.47.10 662 1172 3.2E-151 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 Gene3D G3DSA:3.40.366.10 1245 1528 4.6E-73 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SUPERFAMILY SSF51735 1904 2058 5.8E-7 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 842 858 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2101 2325 1.9E-11 T 12-10-2018 TL08_18355 6450c5762a8ad5674186caa9eecd5dd8 2381 SUPERFAMILY SSF51735 2098 2376 3.02E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_17715 5e5b7615286f846eaf32caee1bf8b2f4 89 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 79 2.0E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17715 5e5b7615286f846eaf32caee1bf8b2f4 89 SUPERFAMILY SSF143800 2 79 6.67E-23 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17715 5e5b7615286f846eaf32caee1bf8b2f4 89 PRINTS PR01249 Ribosomal protein L31 signature 2 19 4.2E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17715 5e5b7615286f846eaf32caee1bf8b2f4 89 PRINTS PR01249 Ribosomal protein L31 signature 60 78 4.2E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17715 5e5b7615286f846eaf32caee1bf8b2f4 89 PRINTS PR01249 Ribosomal protein L31 signature 45 60 4.2E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17715 5e5b7615286f846eaf32caee1bf8b2f4 89 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17715 5e5b7615286f846eaf32caee1bf8b2f4 89 Pfam PF01197 Ribosomal protein L31 2 79 2.2E-31 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17715 5e5b7615286f846eaf32caee1bf8b2f4 89 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 26.188 T 12-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17715 5e5b7615286f846eaf32caee1bf8b2f4 89 Gene3D G3DSA:2.30.170.50 1 83 1.1E-26 T 12-10-2018 TL08_11310 0f9fa31d8d372b271b110d92029d5eae 402 SUPERFAMILY SSF56112 42 324 1.44E-20 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_12985 8b13e871781cda1a9205bfaf9589164f 733 Gene3D G3DSA:1.10.3210.10 3 148 5.8E-6 T 12-10-2018 TL08_12985 8b13e871781cda1a9205bfaf9589164f 733 Pfam PF00270 DEAD/DEAH box helicase 237 393 1.0E-7 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_12985 8b13e871781cda1a9205bfaf9589164f 733 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 19 179 1.6E-19 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain TL08_12985 8b13e871781cda1a9205bfaf9589164f 733 Gene3D G3DSA:3.40.50.300 432 554 3.9E-9 T 12-10-2018 TL08_12985 8b13e871781cda1a9205bfaf9589164f 733 Pfam PF01966 HD domain 20 104 3.7E-5 T 12-10-2018 IPR006674 HD domain TL08_12985 8b13e871781cda1a9205bfaf9589164f 733 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 240 551 9.1E-33 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core TL08_12985 8b13e871781cda1a9205bfaf9589164f 733 SUPERFAMILY SSF52540 239 552 9.18E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12985 8b13e871781cda1a9205bfaf9589164f 733 Gene3D G3DSA:3.40.50.300 206 408 9.2E-13 T 12-10-2018 TL08_12985 8b13e871781cda1a9205bfaf9589164f 733 SMART SM00487 212 421 1.2E-6 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_13010 e7739bab98fcfd0b814d89ae71037407 386 SUPERFAMILY SSF55347 149 346 1.8E-29 T 12-10-2018 TL08_13010 e7739bab98fcfd0b814d89ae71037407 386 Gene3D G3DSA:3.40.50.720 4 143 1.0E-31 T 12-10-2018 TL08_13010 e7739bab98fcfd0b814d89ae71037407 386 SUPERFAMILY SSF51735 52 176 7.6E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_13010 e7739bab98fcfd0b814d89ae71037407 386 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 53 141 8.0E-8 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_13010 e7739bab98fcfd0b814d89ae71037407 386 Gene3D G3DSA:3.30.360.10 144 385 1.7E-64 T 12-10-2018 TL08_12670 3054e86389375d3a72e81b4ac15a2629 135 SUPERFAMILY SSF55298 3 134 1.73E-24 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_12670 3054e86389375d3a72e81b4ac15a2629 135 Gene3D G3DSA:3.30.1330.40 6 135 1.6E-25 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_12670 3054e86389375d3a72e81b4ac15a2629 135 Pfam PF01042 Endoribonuclease L-PSP 26 133 4.8E-15 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 Gene3D G3DSA:1.10.3810.10 59 269 1.6E-71 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 Pfam PF03793 PASTA domain 706 761 1.0E-11 T 12-10-2018 IPR005543 PASTA domain TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 Gene3D G3DSA:3.30.10.20 702 763 6.9E-18 T 12-10-2018 TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 PRINTS PR01217 Proline rich extensin signature 770 791 9.3E-10 T 12-10-2018 TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 PRINTS PR01217 Proline rich extensin signature 816 833 9.3E-10 T 12-10-2018 TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 PRINTS PR01217 Proline rich extensin signature 792 808 9.3E-10 T 12-10-2018 TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 PRINTS PR01217 Proline rich extensin signature 837 857 9.3E-10 T 12-10-2018 TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 SMART SM00740 699 762 1.1E-7 T 12-10-2018 IPR005543 PASTA domain TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 Gene3D G3DSA:3.40.710.10 291 697 3.9E-70 T 12-10-2018 TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 Pfam PF00912 Transglycosylase 70 253 1.2E-59 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 SUPERFAMILY SSF56601 235 692 1.07E-71 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 SUPERFAMILY SSF53955 55 274 1.07E-67 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_01210 00a5b2f2386603bece9ca99e651fdc0a 857 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 620 1.0E-20 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TL08_04685 197184e8eb3066d1bcb388f20ee4cadb 427 Gene3D G3DSA:3.40.190.10 70 376 5.8E-71 T 12-10-2018 TL08_04685 197184e8eb3066d1bcb388f20ee4cadb 427 Gene3D G3DSA:3.40.190.10 154 409 5.8E-71 T 12-10-2018 TL08_04685 197184e8eb3066d1bcb388f20ee4cadb 427 SUPERFAMILY SSF53850 42 409 6.64E-61 T 12-10-2018 TL08_04685 197184e8eb3066d1bcb388f20ee4cadb 427 Pfam PF01547 Bacterial extracellular solute-binding protein 78 330 2.0E-27 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_18910 1027695eb3c2f7c033e65516395adc9d 686 SUPERFAMILY SSF56601 61 389 3.91E-69 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_18910 1027695eb3c2f7c033e65516395adc9d 686 Pfam PF00144 Beta-lactamase 68 398 2.4E-61 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_18910 1027695eb3c2f7c033e65516395adc9d 686 Gene3D G3DSA:3.40.710.10 62 400 1.2E-77 T 12-10-2018 TL08_00405 2ee7511b735275f7abb0369ad76c1796 301 SUPERFAMILY SSF52096 25 238 3.09E-34 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_00405 2ee7511b735275f7abb0369ad76c1796 301 Gene3D G3DSA:3.90.226.10 29 242 2.4E-54 T 12-10-2018 TL08_00405 2ee7511b735275f7abb0369ad76c1796 301 Gene3D G3DSA:3.40.1750.20 140 206 2.4E-54 T 12-10-2018 TL08_00405 2ee7511b735275f7abb0369ad76c1796 301 Pfam PF01343 Peptidase family S49 101 244 3.6E-32 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TL08_13660 6710dcfc9398fb0b60ae1ca9225fbb67 302 Gene3D G3DSA:1.10.3720.10 58 301 1.7E-65 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13660 6710dcfc9398fb0b60ae1ca9225fbb67 302 SUPERFAMILY SSF161098 62 287 1.96E-56 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13660 6710dcfc9398fb0b60ae1ca9225fbb67 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 291 7.5E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_16610 f84e559c240ef9d8b225554aa5f77ac2 243 Pfam PF08713 DNA alkylation repair enzyme 12 227 7.7E-61 T 12-10-2018 IPR014825 DNA alkylation repair enzyme TL08_16610 f84e559c240ef9d8b225554aa5f77ac2 243 SUPERFAMILY SSF48371 14 227 1.06E-41 T 12-10-2018 IPR016024 Armadillo-type fold TL08_16610 f84e559c240ef9d8b225554aa5f77ac2 243 Gene3D G3DSA:1.25.10.90 1 237 6.4E-43 T 12-10-2018 TL08_11370 5b22881e83a13d9b0775df1d9661bfc2 409 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 42 407 25.56 T 12-10-2018 IPR003770 Endolytic murein transglycosylase TL08_11370 5b22881e83a13d9b0775df1d9661bfc2 409 Pfam PF02618 YceG-like family 82 401 1.7E-54 T 12-10-2018 IPR003770 Endolytic murein transglycosylase TL08_11370 5b22881e83a13d9b0775df1d9661bfc2 409 Gene3D G3DSA:1.10.8.1150 77 147 2.6E-8 T 12-10-2018 TL08_11370 5b22881e83a13d9b0775df1d9661bfc2 409 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 37 400 4.6E-35 T 12-10-2018 IPR003770 Endolytic murein transglycosylase TL08_25155 32d416f5fd33878c2c026757c09d47f3 340 Gene3D G3DSA:3.30.1330.60 228 324 9.4E-7 T 12-10-2018 IPR036737 OmpA-like domain superfamily TL08_25155 32d416f5fd33878c2c026757c09d47f3 340 Pfam PF00691 OmpA family 253 318 1.2E-6 T 12-10-2018 IPR006665 OmpA-like domain TL08_25155 32d416f5fd33878c2c026757c09d47f3 340 SUPERFAMILY SSF103088 250 322 1.03E-8 T 12-10-2018 IPR036737 OmpA-like domain superfamily TL08_20575 71eaf6c12f31b9bbe2935ae8e37b180a 489 Pfam PF01593 Flavin containing amine oxidoreductase 17 473 2.8E-38 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TL08_20575 71eaf6c12f31b9bbe2935ae8e37b180a 489 Gene3D G3DSA:3.50.50.60 11 465 8.4E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_20575 71eaf6c12f31b9bbe2935ae8e37b180a 489 Gene3D G3DSA:1.10.3110.10 110 203 8.4E-115 T 12-10-2018 TL08_20575 71eaf6c12f31b9bbe2935ae8e37b180a 489 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 9 474 1.0E-48 T 12-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TL08_20575 71eaf6c12f31b9bbe2935ae8e37b180a 489 Gene3D G3DSA:3.90.660.20 43 424 8.4E-115 T 12-10-2018 TL08_20575 71eaf6c12f31b9bbe2935ae8e37b180a 489 SUPERFAMILY SSF51905 8 474 7.12E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_20575 71eaf6c12f31b9bbe2935ae8e37b180a 489 SUPERFAMILY SSF54373 310 425 2.94E-19 T 12-10-2018 TL08_22500 9ce328faace35c0be9c0cce657697396 501 Pfam PF00890 FAD binding domain 19 485 4.2E-46 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_22500 9ce328faace35c0be9c0cce657697396 501 Gene3D G3DSA:3.50.50.60 18 499 5.3E-113 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_22500 9ce328faace35c0be9c0cce657697396 501 SUPERFAMILY SSF51905 9 501 1.42E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_22500 9ce328faace35c0be9c0cce657697396 501 Gene3D G3DSA:3.90.700.10 273 443 5.3E-113 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_22500 9ce328faace35c0be9c0cce657697396 501 SUPERFAMILY SSF56425 305 447 2.09E-25 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24070 090e85f86e016d2060ce2d382a73237a 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 342 5.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_24070 090e85f86e016d2060ce2d382a73237a 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 319 5.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_24070 090e85f86e016d2060ce2d382a73237a 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 361 5.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_24070 090e85f86e016d2060ce2d382a73237a 370 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 272 363 1.2E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_24070 090e85f86e016d2060ce2d382a73237a 370 Gene3D G3DSA:3.30.565.10 235 362 3.3E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_24070 090e85f86e016d2060ce2d382a73237a 370 SUPERFAMILY SSF55874 252 362 2.75E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_24070 090e85f86e016d2060ce2d382a73237a 370 Pfam PF07730 Histidine kinase 168 231 5.9E-9 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_24070 090e85f86e016d2060ce2d382a73237a 370 SMART SM00387 269 364 3.9E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_06610 32f31c854e42950963e53bb647b73e6d 259 Gene3D G3DSA:1.10.12.10 200 258 3.5E-16 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TL08_06610 32f31c854e42950963e53bb647b73e6d 259 Gene3D G3DSA:3.90.226.10 1 199 5.1E-69 T 12-10-2018 TL08_06610 32f31c854e42950963e53bb647b73e6d 259 SUPERFAMILY SSF52096 3 255 8.06E-79 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_06610 32f31c854e42950963e53bb647b73e6d 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 251 3.5E-66 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TL08_16485 b7c45de396c41e081bd34fa5d7c5def2 450 SUPERFAMILY SSF103473 8 416 5.62E-42 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_16485 b7c45de396c41e081bd34fa5d7c5def2 450 Pfam PF07690 Major Facilitator Superfamily 247 424 3.0E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_16485 b7c45de396c41e081bd34fa5d7c5def2 450 Pfam PF07690 Major Facilitator Superfamily 20 183 1.2E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_16485 b7c45de396c41e081bd34fa5d7c5def2 450 Gene3D G3DSA:1.20.1250.20 8 190 6.7E-13 T 12-10-2018 TL08_16485 b7c45de396c41e081bd34fa5d7c5def2 450 Gene3D G3DSA:1.20.1250.20 233 415 1.5E-15 T 12-10-2018 TL08_21290 76f8116ef53f63159bd447e0341e675f 137 Gene3D G3DSA:3.30.1490.190 89 137 3.5E-22 T 12-10-2018 TL08_21290 76f8116ef53f63159bd447e0341e675f 137 Pfam PF01475 Ferric uptake regulator family 13 129 2.6E-36 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TL08_21290 76f8116ef53f63159bd447e0341e675f 137 Gene3D G3DSA:1.10.10.10 7 88 1.0E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21290 76f8116ef53f63159bd447e0341e675f 137 SUPERFAMILY SSF46785 13 135 7.13E-37 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_20810 e4c1437fde204bcbecbe85a272fbbb54 162 Gene3D G3DSA:3.30.530.20 1 160 1.9E-14 T 12-10-2018 IPR023393 START-like domain superfamily TL08_20810 e4c1437fde204bcbecbe85a272fbbb54 162 SUPERFAMILY SSF55961 1 154 2.09E-16 T 12-10-2018 TL08_20810 e4c1437fde204bcbecbe85a272fbbb54 162 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 150 1.1E-6 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase TL08_11315 05a1e6a547ef8f47fad241dff90e3def 120 SUPERFAMILY SSF51182 3 110 3.52E-23 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_11315 05a1e6a547ef8f47fad241dff90e3def 120 Pfam PF07883 Cupin domain 39 96 1.9E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TL08_11315 05a1e6a547ef8f47fad241dff90e3def 120 Gene3D G3DSA:2.60.120.10 1 105 3.2E-34 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_16340 868f82fc5e3730b59e21106bd7182483 647 Pfam PF02687 FtsX-like permease family 95 191 4.8E-7 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TL08_16340 868f82fc5e3730b59e21106bd7182483 647 Pfam PF02687 FtsX-like permease family 546 639 3.9E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TL08_26090 71baf505a8b2d3ffc589f27967f61db8 182 Gene3D G3DSA:1.10.1740.10 1 83 1.7E-9 T 12-10-2018 TL08_26090 71baf505a8b2d3ffc589f27967f61db8 182 Pfam PF08281 Sigma-70, region 4 110 161 1.1E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_26090 71baf505a8b2d3ffc589f27967f61db8 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 164 4.4E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_26090 71baf505a8b2d3ffc589f27967f61db8 182 SUPERFAMILY SSF88659 107 166 1.18E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_26090 71baf505a8b2d3ffc589f27967f61db8 182 Gene3D G3DSA:1.10.10.10 101 170 6.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26090 71baf505a8b2d3ffc589f27967f61db8 182 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 168 1.5E-44 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 TL08_26090 71baf505a8b2d3ffc589f27967f61db8 182 Pfam PF04542 Sigma-70 region 2 20 79 2.6E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_26090 71baf505a8b2d3ffc589f27967f61db8 182 SUPERFAMILY SSF88946 4 97 1.53E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_05075 3966c82013b101dbd8dc04095509a642 140 Gene3D G3DSA:3.10.450.50 3 139 2.2E-31 T 12-10-2018 TL08_05075 3966c82013b101dbd8dc04095509a642 140 Pfam PF14534 Domain of unknown function (DUF4440) 9 124 1.8E-8 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 TL08_05075 3966c82013b101dbd8dc04095509a642 140 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 5 130 2.1E-10 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 TL08_05075 3966c82013b101dbd8dc04095509a642 140 SUPERFAMILY SSF54427 1 132 1.65E-22 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_18965 23f195fece577aaf0ca2fd7d8c0940ef 398 SMART SM00387 296 394 2.8E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_18965 23f195fece577aaf0ca2fd7d8c0940ef 398 Gene3D G3DSA:3.30.565.10 260 391 7.2E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_18965 23f195fece577aaf0ca2fd7d8c0940ef 398 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 299 387 3.2E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_18965 23f195fece577aaf0ca2fd7d8c0940ef 398 PIRSF PIRSF037434 1 398 1.7E-136 T 12-10-2018 IPR017205 Signal transduction histidine kinase, ChrS TL08_18965 23f195fece577aaf0ca2fd7d8c0940ef 398 SUPERFAMILY SSF55874 268 390 7.47E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_18965 23f195fece577aaf0ca2fd7d8c0940ef 398 Pfam PF07730 Histidine kinase 191 258 8.8E-18 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_12005 14bc49510c3e16e1c17b085da96444a1 659 Pfam PF03109 ABC1 family 207 317 1.3E-29 T 12-10-2018 IPR004147 UbiB domain TL08_12005 14bc49510c3e16e1c17b085da96444a1 659 SUPERFAMILY SSF56112 189 410 6.57E-25 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_18495 a9beeb2fe57ed553b2d12cb80ef1ba9f 397 SUPERFAMILY SSF56645 18 212 1.83E-23 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_18495 a9beeb2fe57ed553b2d12cb80ef1ba9f 397 Gene3D G3DSA:1.20.140.10 218 393 1.2E-29 T 12-10-2018 TL08_18495 a9beeb2fe57ed553b2d12cb80ef1ba9f 397 Gene3D G3DSA:1.10.540.10 10 116 3.4E-23 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_18495 a9beeb2fe57ed553b2d12cb80ef1ba9f 397 Gene3D G3DSA:2.40.110.10 119 212 7.8E-28 T 12-10-2018 TL08_18495 a9beeb2fe57ed553b2d12cb80ef1ba9f 397 PIRSF PIRSF016578 2 395 2.0E-96 T 12-10-2018 TL08_18495 a9beeb2fe57ed553b2d12cb80ef1ba9f 397 SUPERFAMILY SSF47203 239 375 1.37E-9 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_18495 a9beeb2fe57ed553b2d12cb80ef1ba9f 397 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 243 375 1.8E-19 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain TL08_16160 6bc1814bfba0a27beefc9b485f48e189 494 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 472 9.1E-179 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 TL08_16160 6bc1814bfba0a27beefc9b485f48e189 494 SUPERFAMILY SSF51905 6 272 6.48E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_16160 6bc1814bfba0a27beefc9b485f48e189 494 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 3 487 43.417 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 TL08_16160 6bc1814bfba0a27beefc9b485f48e189 494 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 473 7.9E-180 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 TL08_16160 6bc1814bfba0a27beefc9b485f48e189 494 Gene3D G3DSA:3.50.50.60 9 255 7.1E-11 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_16160 6bc1814bfba0a27beefc9b485f48e189 494 Gene3D G3DSA:3.30.9.10 112 177 7.1E-11 T 12-10-2018 TL08_07375 f8632b5d6b9db11f4d4635c8ec54ee11 422 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 416 39.429 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_07375 f8632b5d6b9db11f4d4635c8ec54ee11 422 Gene3D G3DSA:3.65.10.10 22 230 2.7E-151 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TL08_07375 f8632b5d6b9db11f4d4635c8ec54ee11 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 1.1E-99 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TL08_07375 f8632b5d6b9db11f4d4635c8ec54ee11 422 SUPERFAMILY SSF55205 4 417 1.96E-127 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TL08_07375 f8632b5d6b9db11f4d4635c8ec54ee11 422 Gene3D G3DSA:3.65.10.10 7 413 2.7E-151 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TL08_07375 f8632b5d6b9db11f4d4635c8ec54ee11 422 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 415 6.2E-161 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TL08_08985 6232e068c35f7a9aeed05474ab4a64e7 126 Gene3D G3DSA:3.40.50.1010 1 122 7.2E-12 T 12-10-2018 TL08_08985 6232e068c35f7a9aeed05474ab4a64e7 126 Pfam PF01850 PIN domain 3 117 2.2E-14 T 12-10-2018 IPR002716 PIN domain TL08_08985 6232e068c35f7a9aeed05474ab4a64e7 126 SUPERFAMILY SSF88723 1 124 1.49E-21 T 12-10-2018 IPR029060 PIN-like domain superfamily TL08_19030 08e7273b8c0686c3155278280ffedef9 1184 SMART SM00327 1020 1176 0.0029 T 12-10-2018 IPR002035 von Willebrand factor, type A TL08_19030 08e7273b8c0686c3155278280ffedef9 1184 Pfam PF05762 VWA domain containing CoxE-like protein 958 1178 4.1E-56 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like TL08_19030 08e7273b8c0686c3155278280ffedef9 1184 SUPERFAMILY SSF53300 1019 1170 4.29E-22 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_19030 08e7273b8c0686c3155278280ffedef9 1184 Gene3D G3DSA:3.40.50.410 1020 1164 5.5E-8 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_19750 7e17d400f3b7ae36e3cc087fc60ac75c 434 Gene3D G3DSA:2.40.37.20 41 434 8.8E-124 T 12-10-2018 TL08_19750 7e17d400f3b7ae36e3cc087fc60ac75c 434 SMART SM01119 323 421 1.5E-20 T 12-10-2018 IPR026956 D-serine dehydratase-like domain TL08_19750 7e17d400f3b7ae36e3cc087fc60ac75c 434 Pfam PF01168 Alanine racemase, N-terminal domain 59 236 1.5E-10 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_19750 7e17d400f3b7ae36e3cc087fc60ac75c 434 Pfam PF14031 Putative serine dehydratase domain 323 416 3.9E-12 T 12-10-2018 IPR026956 D-serine dehydratase-like domain TL08_19750 7e17d400f3b7ae36e3cc087fc60ac75c 434 Gene3D G3DSA:3.20.20.10 59 299 8.8E-124 T 12-10-2018 IPR029066 PLP-binding barrel TL08_19750 7e17d400f3b7ae36e3cc087fc60ac75c 434 SUPERFAMILY SSF51419 59 298 8.18E-22 T 12-10-2018 IPR029066 PLP-binding barrel TL08_20915 ebfaea6e3a4420268997e26c4cfc7326 421 Pfam PF07730 Histidine kinase 211 275 6.2E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_20915 ebfaea6e3a4420268997e26c4cfc7326 421 SUPERFAMILY SSF55874 299 415 1.08E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_20915 ebfaea6e3a4420268997e26c4cfc7326 421 Gene3D G3DSA:3.30.565.10 290 416 3.5E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_18555 c457f7461342a6da9cfba5b3e2f22f5c 457 SUPERFAMILY SSF48264 26 402 3.54E-49 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18555 c457f7461342a6da9cfba5b3e2f22f5c 457 PRINTS PR00359 B-class P450 signature 202 224 4.5E-8 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18555 c457f7461342a6da9cfba5b3e2f22f5c 457 PRINTS PR00359 B-class P450 signature 107 118 4.5E-8 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18555 c457f7461342a6da9cfba5b3e2f22f5c 457 PRINTS PR00359 B-class P450 signature 153 169 4.5E-8 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18555 c457f7461342a6da9cfba5b3e2f22f5c 457 PRINTS PR00359 B-class P450 signature 341 350 4.5E-8 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18555 c457f7461342a6da9cfba5b3e2f22f5c 457 Gene3D G3DSA:1.10.630.10 17 412 1.3E-72 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18555 c457f7461342a6da9cfba5b3e2f22f5c 457 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_16510 da95d5f74e56ebe9029db70e1c3e007f 369 SUPERFAMILY SSF51679 44 363 3.3E-68 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_16510 da95d5f74e56ebe9029db70e1c3e007f 369 Gene3D G3DSA:3.20.20.30 41 367 2.0E-81 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_16510 da95d5f74e56ebe9029db70e1c3e007f 369 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 45 363 1.1E-99 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 TL08_16510 da95d5f74e56ebe9029db70e1c3e007f 369 Pfam PF00296 Luciferase-like monooxygenase 57 335 1.4E-41 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_14105 0c851f9e34ea0dcaa4a0fba88251927d 309 Gene3D G3DSA:3.40.50.720 118 256 4.6E-45 T 12-10-2018 TL08_14105 0c851f9e34ea0dcaa4a0fba88251927d 309 SUPERFAMILY SSF51735 112 279 8.32E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14105 0c851f9e34ea0dcaa4a0fba88251927d 309 Pfam PF00107 Zinc-binding dehydrogenase 145 254 8.4E-10 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_14105 0c851f9e34ea0dcaa4a0fba88251927d 309 Gene3D G3DSA:3.90.180.10 11 305 4.6E-45 T 12-10-2018 TL08_14105 0c851f9e34ea0dcaa4a0fba88251927d 309 SMART SM00829 9 306 8.4E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_14105 0c851f9e34ea0dcaa4a0fba88251927d 309 SUPERFAMILY SSF50129 7 141 5.22E-17 T 12-10-2018 IPR011032 GroES-like superfamily TL08_25780 807c754ea0ae2baa4864329c70fd3a01 185 SUPERFAMILY SSF55144 29 182 2.43E-14 T 12-10-2018 IPR009097 Cyclic phosphodiesterase TL08_25780 807c754ea0ae2baa4864329c70fd3a01 185 Gene3D G3DSA:3.90.1140.10 16 183 1.1E-20 T 12-10-2018 TL08_25780 807c754ea0ae2baa4864329c70fd3a01 185 Pfam PF13563 2'-5' RNA ligase superfamily 24 165 3.2E-19 T 12-10-2018 TL08_24620 00ec381b8d8e3b1edce38a139d3aafa2 451 SUPERFAMILY SSF103473 11 416 2.49E-45 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_24620 00ec381b8d8e3b1edce38a139d3aafa2 451 Pfam PF07690 Major Facilitator Superfamily 15 376 4.7E-22 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_24620 00ec381b8d8e3b1edce38a139d3aafa2 451 Gene3D G3DSA:1.20.1250.20 6 415 3.9E-36 T 12-10-2018 TL08_00735 50f32e88862b4db8e73c9ce9bda703ea 220 Gene3D G3DSA:3.40.50.150 33 214 4.5E-14 T 12-10-2018 TL08_00735 50f32e88862b4db8e73c9ce9bda703ea 220 SUPERFAMILY SSF53335 47 206 4.81E-8 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_00735 50f32e88862b4db8e73c9ce9bda703ea 220 Pfam PF13578 Methyltransferase domain 54 184 1.8E-12 T 12-10-2018 TL08_18895 c6b1e270ad17797c639c9d18510f746d 325 Gene3D G3DSA:3.40.50.1980 147 325 2.8E-36 T 12-10-2018 TL08_18895 c6b1e270ad17797c639c9d18510f746d 325 Gene3D G3DSA:3.40.50.1980 36 143 1.9E-18 T 12-10-2018 TL08_18895 c6b1e270ad17797c639c9d18510f746d 325 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 304 317 3.1E-6 T 12-10-2018 TL08_18895 c6b1e270ad17797c639c9d18510f746d 325 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 107 122 3.1E-6 T 12-10-2018 TL08_18895 c6b1e270ad17797c639c9d18510f746d 325 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 76 94 3.1E-6 T 12-10-2018 TL08_18895 c6b1e270ad17797c639c9d18510f746d 325 SUPERFAMILY SSF53807 40 318 3.14E-45 T 12-10-2018 TL08_18895 c6b1e270ad17797c639c9d18510f746d 325 Pfam PF01497 Periplasmic binding protein 59 300 3.0E-16 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TL08_25995 f08cd166fef01dab015be02421123495 81 Pfam PF16827 zinc-finger 22 75 5.5E-6 T 12-10-2018 IPR031795 Putative zinc-finger containing protein TL08_23855 e551417c4db030a12ca6a3a2563648c8 301 SUPERFAMILY SSF51556 2 256 1.92E-54 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_23855 e551417c4db030a12ca6a3a2563648c8 301 Gene3D G3DSA:3.20.20.140 2 262 2.7E-49 T 12-10-2018 TL08_23855 e551417c4db030a12ca6a3a2563648c8 301 Pfam PF01026 TatD related DNase 4 226 2.0E-15 T 12-10-2018 IPR001130 TatD family GO:0016788 TL08_23855 e551417c4db030a12ca6a3a2563648c8 301 PIRSF PIRSF005295 2 259 9.2E-106 T 12-10-2018 IPR012022 Protein of unknown function UCP005295 TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 12-10-2018 IPR018215 ClpP, Ser active site TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 Pfam PF00574 Clp protease 27 201 8.8E-74 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 38.547 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 Gene3D G3DSA:3.90.226.10 1 207 8.1E-78 T 12-10-2018 TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 12-10-2018 IPR033135 ClpP, histidine active site TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 SUPERFAMILY SSF52096 20 204 1.58E-62 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_08055 ddbf41ef44d43dafd79e3916ee0e6f67 208 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 Gene3D G3DSA:3.20.20.70 821 1245 6.3E-185 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 Gene3D G3DSA:3.20.20.70 465 820 8.3E-130 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 Pfam PF00310 Glutamine amidotransferases class-II 22 457 2.8E-162 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 SUPERFAMILY SSF51395 472 1234 3.87E-254 T 12-10-2018 TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 Pfam PF01493 GXGXG motif 1286 1463 3.1E-75 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 Pfam PF04898 Glutamate synthase central domain 484 770 3.1E-109 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 Pfam PF01645 Conserved region in glutamate synthase 836 1200 2.2E-149 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 Gene3D G3DSA:2.160.20.60 1259 1525 1.0E-100 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 Gene3D G3DSA:3.60.20.10 22 464 2.5E-165 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 SUPERFAMILY SSF69336 1255 1516 2.88E-87 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TL08_17885 f08c524c9b18b0695c1173eef6438405 1537 SUPERFAMILY SSF56235 22 459 3.38E-135 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_25415 7ce12fcc6279698540756222d92a6c71 420 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_25415 7ce12fcc6279698540756222d92a6c71 420 Gene3D G3DSA:3.30.200.20 4 91 5.0E-28 T 12-10-2018 TL08_25415 7ce12fcc6279698540756222d92a6c71 420 Pfam PF00069 Protein kinase domain 13 261 4.5E-39 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_25415 7ce12fcc6279698540756222d92a6c71 420 SUPERFAMILY SSF56112 9 321 4.32E-62 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_25415 7ce12fcc6279698540756222d92a6c71 420 SMART SM00220 13 274 3.9E-48 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_25415 7ce12fcc6279698540756222d92a6c71 420 Gene3D G3DSA:1.10.510.10 95 280 1.6E-40 T 12-10-2018 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 Pfam PF02867 Ribonucleotide reductase, barrel domain 285 825 2.2E-179 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 669 691 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 208 281 9.3E-21 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 SUPERFAMILY SSF48168 67 283 6.02E-58 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 SUPERFAMILY SSF51998 284 830 2.38E-174 T 12-10-2018 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 Gene3D G3DSA:3.20.70.20 135 836 7.0E-240 T 12-10-2018 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 PRINTS PR01183 Ribonucleotide reductase large chain signature 360 379 1.1E-43 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 PRINTS PR01183 Ribonucleotide reductase large chain signature 680 707 1.1E-43 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 PRINTS PR01183 Ribonucleotide reductase large chain signature 603 626 1.1E-43 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 PRINTS PR01183 Ribonucleotide reductase large chain signature 495 506 1.1E-43 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 PRINTS PR01183 Ribonucleotide reductase large chain signature 575 597 1.1E-43 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 PRINTS PR01183 Ribonucleotide reductase large chain signature 537 560 1.1E-43 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10640 e97ab4e824a35a837c74417d0a15437e 894 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 212 828 8.1E-206 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_24390 896617864967fa0623c9aa6355a0c8b7 399 Gene3D G3DSA:3.90.20.10 69 201 1.1E-5 T 12-10-2018 TL08_24390 896617864967fa0623c9aa6355a0c8b7 399 SUPERFAMILY SSF58113 202 315 1.44E-5 T 12-10-2018 TL08_24390 896617864967fa0623c9aa6355a0c8b7 399 SUPERFAMILY SSF58113 97 230 2.88E-5 T 12-10-2018 TL08_24390 896617864967fa0623c9aa6355a0c8b7 399 Gene3D G3DSA:1.20.120.20 239 353 9.1E-6 T 12-10-2018 TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 SUPERFAMILY SSF52540 276 508 3.34E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 98 3.5E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 Gene3D G3DSA:1.25.40.10 103 269 8.3E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 Pfam PF03704 Bacterial transcriptional activator domain 105 250 1.2E-38 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 SUPERFAMILY SSF48452 101 271 6.83E-36 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 Pfam PF13191 AAA ATPase domain 278 431 2.4E-21 T 12-10-2018 TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 SUPERFAMILY SSF46894 7 98 8.79E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 SMART SM00862 19 98 6.5E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 SMART SM01043 105 250 3.6E-46 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_15070 ed77065ec00be400e1807cb75a5fd6de 1105 Gene3D G3DSA:1.10.10.10 1 100 3.6E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06090 e421763c9665e5733dd03e63a80547bf 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 0.002 T 12-10-2018 TL08_06090 e421763c9665e5733dd03e63a80547bf 249 SUPERFAMILY SSF51735 5 246 4.55E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_06090 e421763c9665e5733dd03e63a80547bf 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_06090 e421763c9665e5733dd03e63a80547bf 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06090 e421763c9665e5733dd03e63a80547bf 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06090 e421763c9665e5733dd03e63a80547bf 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06090 e421763c9665e5733dd03e63a80547bf 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06090 e421763c9665e5733dd03e63a80547bf 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06090 e421763c9665e5733dd03e63a80547bf 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 6.2E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06090 e421763c9665e5733dd03e63a80547bf 249 Gene3D G3DSA:3.40.50.720 1 248 3.8E-73 T 12-10-2018 TL08_06090 e421763c9665e5733dd03e63a80547bf 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 6.7E-59 T 12-10-2018 TL08_24460 47fd74b7ad3d1302f97335ee341e3579 214 Gene3D G3DSA:2.80.10.50 112 171 1.3E-14 T 12-10-2018 TL08_24460 47fd74b7ad3d1302f97335ee341e3579 214 Gene3D G3DSA:2.80.10.50 172 212 1.6E-13 T 12-10-2018 TL08_24460 47fd74b7ad3d1302f97335ee341e3579 214 Pfam PF00652 Ricin-type beta-trefoil lectin domain 78 209 7.5E-23 T 12-10-2018 IPR000772 Ricin B, lectin domain TL08_24460 47fd74b7ad3d1302f97335ee341e3579 214 SUPERFAMILY SSF50370 77 210 2.92E-38 T 12-10-2018 IPR035992 Ricin B-like lectins TL08_24460 47fd74b7ad3d1302f97335ee341e3579 214 SMART SM00458 70 212 7.8E-16 T 12-10-2018 IPR000772 Ricin B, lectin domain TL08_24460 47fd74b7ad3d1302f97335ee341e3579 214 Gene3D G3DSA:2.80.10.50 41 111 3.2E-8 T 12-10-2018 TL08_02235 e76cb479c557301f0d5050cf03c9fa07 246 SUPERFAMILY SSF52540 36 215 1.33E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_02235 e76cb479c557301f0d5050cf03c9fa07 246 SMART SM00382 40 214 9.7E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_02235 e76cb479c557301f0d5050cf03c9fa07 246 Gene3D G3DSA:3.40.50.300 29 96 5.6E-7 T 12-10-2018 TL08_02235 e76cb479c557301f0d5050cf03c9fa07 246 Pfam PF13476 AAA domain 37 63 1.3E-6 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain TL08_02235 e76cb479c557301f0d5050cf03c9fa07 246 Gene3D G3DSA:3.40.50.300 111 212 2.6E-8 T 12-10-2018 TL08_08515 fe21d9f3bac996d5ded8b699b9364469 296 Gene3D G3DSA:1.10.3720.10 50 264 1.1E-41 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08515 fe21d9f3bac996d5ded8b699b9364469 296 SUPERFAMILY SSF161098 62 260 2.09E-35 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08515 fe21d9f3bac996d5ded8b699b9364469 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 261 8.5E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_08515 fe21d9f3bac996d5ded8b699b9364469 296 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 62 151 8.9E-16 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TL08_10010 d6eb3c0117d2c1ab5366b6ca9bd443d7 605 Gene3D G3DSA:3.40.50.300 355 602 3.2E-88 T 12-10-2018 TL08_10010 d6eb3c0117d2c1ab5366b6ca9bd443d7 605 Pfam PF00664 ABC transporter transmembrane region 40 312 6.9E-55 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_10010 d6eb3c0117d2c1ab5366b6ca9bd443d7 605 Pfam PF00005 ABC transporter 376 524 1.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_10010 d6eb3c0117d2c1ab5366b6ca9bd443d7 605 SMART SM00382 384 576 2.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_10010 d6eb3c0117d2c1ab5366b6ca9bd443d7 605 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_10010 d6eb3c0117d2c1ab5366b6ca9bd443d7 605 Gene3D G3DSA:1.20.1560.10 3 346 2.7E-98 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_10010 d6eb3c0117d2c1ab5366b6ca9bd443d7 605 SUPERFAMILY SSF52540 351 595 2.22E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10010 d6eb3c0117d2c1ab5366b6ca9bd443d7 605 SUPERFAMILY SSF90123 18 346 6.15E-84 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 Gene3D G3DSA:3.40.50.300 307 507 2.6E-97 T 12-10-2018 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 247 518 1.0E-101 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 SUPERFAMILY SSF52540 315 518 3.06E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 492 505 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 SUPERFAMILY SSF47364 218 297 1.83E-15 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 SMART SM00382 319 469 1.0E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 Pfam PF00448 SRP54-type protein, GTPase domain 320 518 1.5E-71 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 246 519 55.949 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 Gene3D G3DSA:1.20.120.140 221 517 2.6E-97 T 12-10-2018 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 SMART SM00962 320 519 3.1E-99 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 SMART SM00963 223 303 7.6E-15 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_22285 fbaeea5e005e3a464a09b92394751ac4 519 Pfam PF02881 SRP54-type protein, helical bundle domain 238 298 5.4E-7 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TL08_07355 ac1ac7453d57f1f6e5a21be63132657b 178 SUPERFAMILY SSF88946 5 89 3.61E-9 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_07355 ac1ac7453d57f1f6e5a21be63132657b 178 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 161 5.3E-50 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 TL08_07355 ac1ac7453d57f1f6e5a21be63132657b 178 Gene3D G3DSA:1.10.1740.10 1 79 1.5E-5 T 12-10-2018 TL08_07355 ac1ac7453d57f1f6e5a21be63132657b 178 Pfam PF08281 Sigma-70, region 4 103 156 4.9E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_07355 ac1ac7453d57f1f6e5a21be63132657b 178 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 158 2.1E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_07355 ac1ac7453d57f1f6e5a21be63132657b 178 Gene3D G3DSA:1.10.10.10 81 164 4.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07355 ac1ac7453d57f1f6e5a21be63132657b 178 SUPERFAMILY SSF88659 102 160 3.36E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_07355 ac1ac7453d57f1f6e5a21be63132657b 178 Pfam PF04542 Sigma-70 region 2 18 77 1.1E-5 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_06220 3a9577ced1fc3568ddb0d36c79caf79d 217 SUPERFAMILY SSF56784 2 215 3.14E-41 T 12-10-2018 IPR036412 HAD-like superfamily TL08_06220 3a9577ced1fc3568ddb0d36c79caf79d 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 178 1.2E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_06220 3a9577ced1fc3568ddb0d36c79caf79d 217 TIGRFAM TIGR03351 PhnX-like: phosphonatase-like hydrolase 2 216 3.5E-78 T 12-10-2018 IPR022468 Phosphonatase-like hydrolase TL08_06220 3a9577ced1fc3568ddb0d36c79caf79d 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 181 4.6E-18 T 12-10-2018 TL08_06220 3a9577ced1fc3568ddb0d36c79caf79d 217 Gene3D G3DSA:3.40.50.1000 64 216 4.6E-35 T 12-10-2018 IPR023214 HAD superfamily TL08_13595 2bfa7185919a9ce5feaebec7a5551a25 341 Pfam PF00005 ABC transporter 24 172 6.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13595 2bfa7185919a9ce5feaebec7a5551a25 341 SUPERFAMILY SSF52540 4 243 1.0E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13595 2bfa7185919a9ce5feaebec7a5551a25 341 SMART SM00930 265 339 4.4E-14 T 12-10-2018 IPR018449 NIL domain TL08_13595 2bfa7185919a9ce5feaebec7a5551a25 341 SMART SM00382 33 221 9.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13595 2bfa7185919a9ce5feaebec7a5551a25 341 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_13595 2bfa7185919a9ce5feaebec7a5551a25 341 Pfam PF09383 NIL domain 277 333 1.9E-9 T 12-10-2018 IPR018449 NIL domain TL08_13595 2bfa7185919a9ce5feaebec7a5551a25 341 Gene3D G3DSA:3.40.50.300 2 252 5.1E-73 T 12-10-2018 TL08_13595 2bfa7185919a9ce5feaebec7a5551a25 341 SUPERFAMILY SSF55021 260 336 8.47E-11 T 12-10-2018 TL08_13595 2bfa7185919a9ce5feaebec7a5551a25 341 Gene3D G3DSA:3.30.70.260 255 341 9.3E-6 T 12-10-2018 TL08_14910 ae2fc685ae34063cbd188804bcb7d952 334 Gene3D G3DSA:3.40.50.1100 42 147 4.7E-82 T 12-10-2018 TL08_14910 ae2fc685ae34063cbd188804bcb7d952 334 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 10 308 3.0E-116 T 12-10-2018 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA TL08_14910 ae2fc685ae34063cbd188804bcb7d952 334 Gene3D G3DSA:3.40.50.1100 25 299 4.7E-82 T 12-10-2018 TL08_14910 ae2fc685ae34063cbd188804bcb7d952 334 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 275 5.4E-51 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_14910 ae2fc685ae34063cbd188804bcb7d952 334 SUPERFAMILY SSF53686 19 310 3.93E-68 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 SUPERFAMILY SSF51905 5 347 2.09E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 2.3E-5 T 12-10-2018 TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 2.3E-5 T 12-10-2018 TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 2.3E-5 T 12-10-2018 TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 7.9E-12 T 12-10-2018 TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 7.9E-12 T 12-10-2018 TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 7.9E-12 T 12-10-2018 TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 7.9E-12 T 12-10-2018 TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 Gene3D G3DSA:3.50.50.100 7 414 4.9E-118 T 12-10-2018 TL08_03820 ef31c613c5c96c6bcae5a516f7a1022d 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 336 1.8E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 SMART SM00345 15 74 2.1E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 SUPERFAMILY SSF46785 6 78 5.77E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 Gene3D G3DSA:1.20.120.530 89 223 5.2E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 SMART SM00895 94 219 3.8E-19 T 12-10-2018 IPR011711 GntR, C-terminal TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 2.7E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 SUPERFAMILY SSF48008 90 224 5.75E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 Pfam PF07729 FCD domain 94 212 4.5E-20 T 12-10-2018 IPR011711 GntR, C-terminal TL08_09000 94f001d49bb3b1cab32edc1d50591d1e 234 Gene3D G3DSA:1.10.10.10 6 82 2.5E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17330 d7afc110323aafebd617aeb96709fcd5 212 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 132 211 1.8E-19 T 12-10-2018 IPR039561 Peptidase M15C GO:0008233 TL08_17330 d7afc110323aafebd617aeb96709fcd5 212 SUPERFAMILY SSF55166 57 210 4.71E-30 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TL08_17330 d7afc110323aafebd617aeb96709fcd5 212 Gene3D G3DSA:3.30.1380.10 69 210 2.0E-17 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TL08_11140 1e8bfb4e1e92c337c814b072c202131d 226 SUPERFAMILY SSF52317 8 223 2.52E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_11140 1e8bfb4e1e92c337c814b072c202131d 226 Gene3D G3DSA:3.40.50.880 2 225 1.4E-78 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_11140 1e8bfb4e1e92c337c814b072c202131d 226 Pfam PF06283 Trehalose utilisation 9 221 2.6E-75 T 12-10-2018 IPR029010 ThuA-like domain TL08_15530 4c9d839a0f3c3fac15c0ca638f8900b6 343 Gene3D G3DSA:3.20.20.70 68 310 1.6E-5 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_15530 4c9d839a0f3c3fac15c0ca638f8900b6 343 SMART SM00729 66 292 0.0012 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_15530 4c9d839a0f3c3fac15c0ca638f8900b6 343 Pfam PF04055 Radical SAM superfamily 70 248 3.1E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_15530 4c9d839a0f3c3fac15c0ca638f8900b6 343 SUPERFAMILY SSF102114 61 276 3.79E-12 T 12-10-2018 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 Pfam PF00664 ABC transporter transmembrane region 6 274 2.9E-33 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 Pfam PF00664 ABC transporter transmembrane region 682 952 5.0E-34 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 Gene3D G3DSA:1.20.1560.10 1 302 1.5E-67 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 Pfam PF00005 ABC transporter 337 490 3.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 Gene3D G3DSA:1.20.1560.10 653 985 2.3E-80 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 ProSitePatterns PS00211 ABC transporters family signature. 462 476 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 Gene3D G3DSA:3.40.50.300 993 1242 6.3E-82 T 12-10-2018 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 Gene3D G3DSA:3.40.50.300 317 565 4.3E-81 T 12-10-2018 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 SUPERFAMILY SSF90123 666 985 4.97E-74 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 SUPERFAMILY SSF52540 312 557 2.34E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 SMART SM00382 346 536 3.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 SMART SM00382 1025 1211 7.1E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 SUPERFAMILY SSF90123 2 310 1.96E-65 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 SUPERFAMILY SSF52540 992 1233 2.33E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23005 cfb4d1c8f12e124e37357ad1473b3baf 1256 Pfam PF00005 ABC transporter 1016 1165 2.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12830 9539b46dec7fb1f3278977528f314fde 449 SUPERFAMILY SSF55874 173 290 7.73E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_12830 9539b46dec7fb1f3278977528f314fde 449 SMART SM00387 180 291 3.7E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_12830 9539b46dec7fb1f3278977528f314fde 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 184 288 4.0E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_12830 9539b46dec7fb1f3278977528f314fde 449 Gene3D G3DSA:1.10.287.130 89 138 7.0E-16 T 12-10-2018 TL08_12830 9539b46dec7fb1f3278977528f314fde 449 Gene3D G3DSA:3.30.565.10 139 287 7.0E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_26315 4e9a381ee17c7e74e6c46440360920f5 541 SUPERFAMILY SSF103473 40 533 1.83E-66 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_26315 4e9a381ee17c7e74e6c46440360920f5 541 Pfam PF07690 Major Facilitator Superfamily 64 459 1.5E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_26315 4e9a381ee17c7e74e6c46440360920f5 541 Gene3D G3DSA:1.20.1720.10 63 283 3.4E-44 T 12-10-2018 TL08_26315 4e9a381ee17c7e74e6c46440360920f5 541 PRINTS PR01035 Tetracycline resistance protein signature 61 77 1.5E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_26315 4e9a381ee17c7e74e6c46440360920f5 541 PRINTS PR01035 Tetracycline resistance protein signature 185 207 1.5E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 Gene3D G3DSA:3.20.20.450 7 262 4.0E-35 T 12-10-2018 IPR035919 EAL domain superfamily TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 Pfam PF00990 Diguanylate cyclase, GGDEF domain 419 501 1.7E-10 T 12-10-2018 IPR000160 GGDEF domain TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 Pfam PF00563 EAL domain 30 248 2.5E-30 T 12-10-2018 IPR001633 EAL domain TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 414 502 2.2E-10 T 12-10-2018 IPR000160 GGDEF domain TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 SMART SM00267 405 567 4.1E-6 T 12-10-2018 IPR000160 GGDEF domain TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 SUPERFAMILY SSF55073 421 550 6.36E-15 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 Gene3D G3DSA:3.30.70.270 407 558 7.5E-17 T 12-10-2018 TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 SUPERFAMILY SSF141868 30 249 1.96E-34 T 12-10-2018 IPR035919 EAL domain superfamily TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 SMART SM00052 8 257 2.7E-10 T 12-10-2018 IPR001633 EAL domain TL08_11850 252f9e3ac559ae7d1be955ece6425679 598 SUPERFAMILY SSF54631 356 428 2.42E-6 T 12-10-2018 TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 Gene3D G3DSA:3.40.1360.10 76 202 6.0E-42 T 12-10-2018 TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 SMART SM00278 11 30 0.0081 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 SUPERFAMILY SSF111304 2 202 3.66E-68 T 12-10-2018 IPR023627 Recombination protein RecR TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 Gene3D G3DSA:1.10.8.420 1 51 1.4E-19 T 12-10-2018 TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 SMART SM00493 79 168 1.0E-13 T 12-10-2018 IPR006171 TOPRIM domain TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 100.292 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 TIGRFAM TIGR00615 recR: recombination protein RecR 2 200 3.2E-78 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 Pfam PF13662 Toprim domain 81 175 1.1E-21 T 12-10-2018 IPR006171 TOPRIM domain TL08_01075 651f7a220a6e8cbdd242b5fcfdf2400c 202 Pfam PF02132 RecR protein 38 77 2.5E-13 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger TL08_10985 80db2b2f2213debf987a585d826c943c 488 Gene3D G3DSA:3.40.309.10 263 456 5.4E-170 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_10985 80db2b2f2213debf987a585d826c943c 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TL08_10985 80db2b2f2213debf987a585d826c943c 488 Pfam PF00171 Aldehyde dehydrogenase family 20 484 8.5E-163 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_10985 80db2b2f2213debf987a585d826c943c 488 Gene3D G3DSA:3.40.605.10 20 479 5.4E-170 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_10985 80db2b2f2213debf987a585d826c943c 488 SUPERFAMILY SSF53720 9 486 1.44E-163 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_00130 68783f5f38b501cf60af7661340a0ee9 488 Gene3D G3DSA:3.40.710.10 137 481 4.3E-137 T 12-10-2018 TL08_00130 68783f5f38b501cf60af7661340a0ee9 488 Gene3D G3DSA:3.90.1310.10 58 383 4.3E-137 T 12-10-2018 TL08_00130 68783f5f38b501cf60af7661340a0ee9 488 SUPERFAMILY SSF56519 74 118 5.23E-6 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TL08_00130 68783f5f38b501cf60af7661340a0ee9 488 Pfam PF00905 Penicillin binding protein transpeptidase domain 157 481 2.6E-67 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TL08_00130 68783f5f38b501cf60af7661340a0ee9 488 SUPERFAMILY SSF56601 138 483 2.49E-76 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_20740 cb10e7b2d94067e7de5043d8c6d209c1 393 Pfam PF01261 Xylose isomerase-like TIM barrel 53 226 5.8E-8 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_20740 cb10e7b2d94067e7de5043d8c6d209c1 393 SUPERFAMILY SSF51658 30 367 1.66E-91 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_20740 cb10e7b2d94067e7de5043d8c6d209c1 393 Gene3D G3DSA:3.20.20.150 8 385 3.5E-130 T 12-10-2018 TL08_20740 cb10e7b2d94067e7de5043d8c6d209c1 393 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 78 341 1.0E-7 T 12-10-2018 TL08_20740 cb10e7b2d94067e7de5043d8c6d209c1 393 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 12 383 2.7E-192 T 12-10-2018 IPR013457 Rhamnose isomerase-related TL08_00070 4a82a98d45b8da338c07c63960ebca78 181 SUPERFAMILY SSF55724 44 181 1.26E-42 T 12-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich TL08_00070 4a82a98d45b8da338c07c63960ebca78 181 Pfam PF09449 Domain of unknown function (DUF2020) 44 181 9.0E-37 T 12-10-2018 IPR018567 Domain of unknown function DUF2020 TL08_00070 4a82a98d45b8da338c07c63960ebca78 181 Gene3D G3DSA:3.40.1000.10 32 181 1.1E-50 T 12-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich TL08_26155 13477d1a36a4e72e600a94318cb401a7 542 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 11 535 1.7E-90 T 12-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 TL08_26155 13477d1a36a4e72e600a94318cb401a7 542 Pfam PF00999 Sodium/hydrogen exchanger family 6 407 2.2E-54 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TL08_26155 13477d1a36a4e72e600a94318cb401a7 542 Gene3D G3DSA:1.20.1530.20 1 410 4.3E-6 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TL08_26155 13477d1a36a4e72e600a94318cb401a7 542 PRINTS PR00173 Glutamate-aspartate symporter signature 305 324 6.4E-6 T 12-10-2018 TL08_26155 13477d1a36a4e72e600a94318cb401a7 542 PRINTS PR00173 Glutamate-aspartate symporter signature 172 197 6.4E-6 T 12-10-2018 TL08_26155 13477d1a36a4e72e600a94318cb401a7 542 PRINTS PR00173 Glutamate-aspartate symporter signature 129 149 6.4E-6 T 12-10-2018 TL08_26155 13477d1a36a4e72e600a94318cb401a7 542 PRINTS PR00173 Glutamate-aspartate symporter signature 83 103 6.4E-6 T 12-10-2018 TL08_13125 f268437683751bc49f3f5e9af88acd1e 631 SUPERFAMILY SSF69322 46 315 1.02E-10 T 12-10-2018 TL08_13125 f268437683751bc49f3f5e9af88acd1e 631 Pfam PF00326 Prolyl oligopeptidase family 412 618 1.6E-43 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_13125 f268437683751bc49f3f5e9af88acd1e 631 SUPERFAMILY SSF53474 358 618 1.14E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13125 f268437683751bc49f3f5e9af88acd1e 631 Gene3D G3DSA:2.120.10.30 14 223 1.5E-5 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_13125 f268437683751bc49f3f5e9af88acd1e 631 Gene3D G3DSA:3.40.50.1820 351 631 2.3E-78 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 Gene3D G3DSA:2.40.500.20 84 201 3.7E-44 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 PIRSF PIRSF000349 1 201 4.7E-77 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 SUPERFAMILY SSF46609 2 84 2.09E-32 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 90 192 9.3E-34 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 83 9.3E-32 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 159 166 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 PRINTS PR01703 Manganese superoxide dismutase signature 66 79 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 PRINTS PR01703 Manganese superoxide dismutase signature 119 127 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 PRINTS PR01703 Manganese superoxide dismutase signature 157 169 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 Gene3D G3DSA:1.10.287.990 20 83 3.2E-26 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_10725 023c17ffa014f9c7a445419a9179caf3 202 SUPERFAMILY SSF54719 83 197 8.51E-43 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TL08_01085 ea9f4bbe005134304c1c68fcd9a78ca7 565 Gene3D G3DSA:3.40.190.10 235 551 2.2E-131 T 12-10-2018 TL08_01085 ea9f4bbe005134304c1c68fcd9a78ca7 565 PIRSF PIRSF002741 9 564 1.0E-99 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_01085 ea9f4bbe005134304c1c68fcd9a78ca7 565 SUPERFAMILY SSF53850 43 562 8.32E-112 T 12-10-2018 TL08_01085 ea9f4bbe005134304c1c68fcd9a78ca7 565 Gene3D G3DSA:3.90.76.10 61 234 2.2E-131 T 12-10-2018 TL08_01085 ea9f4bbe005134304c1c68fcd9a78ca7 565 Gene3D G3DSA:3.10.105.10 318 538 2.2E-131 T 12-10-2018 TL08_01085 ea9f4bbe005134304c1c68fcd9a78ca7 565 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 481 1.1E-83 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_08915 7a9aa6f32542362de216a5c82c701984 409 SMART SM00382 52 234 2.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08915 7a9aa6f32542362de216a5c82c701984 409 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_08915 7a9aa6f32542362de216a5c82c701984 409 Gene3D G3DSA:3.40.50.300 27 245 8.9E-63 T 12-10-2018 TL08_08915 7a9aa6f32542362de216a5c82c701984 409 SUPERFAMILY SSF50331 266 395 1.26E-15 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TL08_08915 7a9aa6f32542362de216a5c82c701984 409 Gene3D G3DSA:2.40.50.940 246 328 2.2E-7 T 12-10-2018 TL08_08915 7a9aa6f32542362de216a5c82c701984 409 Pfam PF00005 ABC transporter 43 185 9.6E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_08915 7a9aa6f32542362de216a5c82c701984 409 SUPERFAMILY SSF52540 28 261 4.31E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08915 7a9aa6f32542362de216a5c82c701984 409 Pfam PF08402 TOBE domain 311 396 5.7E-13 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TL08_07640 52df6d39db3bd036f7bdbe343233771a 138 SUPERFAMILY SSF101386 35 134 4.58E-26 T 12-10-2018 TL08_07640 52df6d39db3bd036f7bdbe343233771a 138 PIRSF PIRSF029826 17 137 1.2E-34 T 12-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 TL08_07640 52df6d39db3bd036f7bdbe343233771a 138 Pfam PF12643 MazG-like family 55 131 3.5E-7 T 12-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 TL08_07640 52df6d39db3bd036f7bdbe343233771a 138 Gene3D G3DSA:1.10.287.1080 16 129 3.0E-32 T 12-10-2018 TL08_25945 bb17c0fedb9021db036a23cf0a8adec7 212 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 48 211 32.807 T 12-10-2018 IPR022939 Uncharacterised protein family UPF0678 TL08_25945 bb17c0fedb9021db036a23cf0a8adec7 212 Pfam PF08768 Domain of unknown function (DUF1794) 57 209 2.1E-46 T 12-10-2018 IPR014878 Domain of unknown function DUF1794 TL08_25945 bb17c0fedb9021db036a23cf0a8adec7 212 SUPERFAMILY SSF50814 51 210 7.67E-38 T 12-10-2018 IPR012674 Calycin TL08_25945 bb17c0fedb9021db036a23cf0a8adec7 212 Gene3D G3DSA:2.40.128.20 18 212 8.9E-74 T 12-10-2018 IPR012674 Calycin TL08_13230 f7de713c173a3343c3a9c743f0217474 399 Pfam PF00285 Citrate synthase, C-terminal domain 73 388 3.1E-63 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 ProSitePatterns PS00480 Citrate synthase signature. 290 302 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 Pfam PF12728 Helix-turn-helix domain 9 61 1.0E-7 T 12-10-2018 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 Gene3D G3DSA:1.10.580.10 85 378 1.1E-61 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 SUPERFAMILY SSF48256 72 396 2.09E-69 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 Gene3D G3DSA:1.10.230.10 258 352 1.1E-61 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain TL08_13230 f7de713c173a3343c3a9c743f0217474 399 Gene3D G3DSA:1.10.1660.10 8 74 4.7E-6 T 12-10-2018 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 SUPERFAMILY SSF46955 8 60 5.49E-7 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_13230 f7de713c173a3343c3a9c743f0217474 399 PRINTS PR00143 Citrate synthase signature 210 225 1.7E-25 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 PRINTS PR00143 Citrate synthase signature 358 372 1.7E-25 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 PRINTS PR00143 Citrate synthase signature 338 354 1.7E-25 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 PRINTS PR00143 Citrate synthase signature 283 303 1.7E-25 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13230 f7de713c173a3343c3a9c743f0217474 399 PRINTS PR00143 Citrate synthase signature 232 260 1.7E-25 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_17240 43946bdc33d47f44d08900d6b2bc2423 66 PIRSF PIRSF002599 1 66 2.5E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 TL08_17240 43946bdc33d47f44d08900d6b2bc2423 66 SMART SM00357 3 66 3.5E-28 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 TL08_17240 43946bdc33d47f44d08900d6b2bc2423 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.0E-29 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_17240 43946bdc33d47f44d08900d6b2bc2423 66 PRINTS PR00050 Cold shock protein signature 39 57 2.1E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_17240 43946bdc33d47f44d08900d6b2bc2423 66 PRINTS PR00050 Cold shock protein signature 4 19 2.1E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_17240 43946bdc33d47f44d08900d6b2bc2423 66 PRINTS PR00050 Cold shock protein signature 24 33 2.1E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_17240 43946bdc33d47f44d08900d6b2bc2423 66 SUPERFAMILY SSF50249 1 64 1.29E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_17240 43946bdc33d47f44d08900d6b2bc2423 66 Gene3D G3DSA:2.40.50.140 1 64 2.6E-31 T 12-10-2018 TL08_17240 43946bdc33d47f44d08900d6b2bc2423 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site TL08_00265 2dd495736b361b77c5db72ec96a7dbd1 260 Gene3D G3DSA:1.10.3720.10 56 254 5.2E-29 T 12-10-2018 IPR035906 MetI-like superfamily TL08_00265 2dd495736b361b77c5db72ec96a7dbd1 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 251 3.2E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_00265 2dd495736b361b77c5db72ec96a7dbd1 260 SUPERFAMILY SSF161098 60 246 1.44E-31 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23390 3b41c128cde9db84d16fc7716b697935 183 SUPERFAMILY SSF55811 31 165 2.57E-18 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_23390 3b41c128cde9db84d16fc7716b697935 183 Gene3D G3DSA:3.90.79.10 5 177 1.7E-33 T 12-10-2018 TL08_23390 3b41c128cde9db84d16fc7716b697935 183 Pfam PF00293 NUDIX domain 47 160 5.5E-9 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 Gene3D G3DSA:1.10.10.10 1 67 2.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 Gene3D G3DSA:1.20.120.530 70 207 2.0E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 SUPERFAMILY SSF46785 3 70 5.56E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 Pfam PF07729 FCD domain 76 197 7.3E-26 T 12-10-2018 IPR011711 GntR, C-terminal TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 1.1E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 1.1E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 SMART SM00895 76 198 1.0E-20 T 12-10-2018 IPR011711 GntR, C-terminal TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 SMART SM00345 8 66 1.1E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.2E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_17035 a44df90cbeb66d0c9aea5912be5d468c 208 SUPERFAMILY SSF48008 72 201 3.4E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_11215 93741ffa623be9fe30cb4b1e1eef9746 834 Pfam PF12029 Domain of unknown function (DUF3516) 374 829 8.2E-217 T 12-10-2018 IPR021904 Protein of unknown function DUF3516 TL08_11215 93741ffa623be9fe30cb4b1e1eef9746 834 Gene3D G3DSA:3.40.50.300 25 200 2.2E-37 T 12-10-2018 TL08_11215 93741ffa623be9fe30cb4b1e1eef9746 834 SUPERFAMILY SSF52540 46 375 1.15E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11215 93741ffa623be9fe30cb4b1e1eef9746 834 Gene3D G3DSA:3.40.50.300 201 388 2.7E-41 T 12-10-2018 TL08_11215 93741ffa623be9fe30cb4b1e1eef9746 834 Pfam PF00271 Helicase conserved C-terminal domain 284 363 6.5E-6 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_11215 93741ffa623be9fe30cb4b1e1eef9746 834 SMART SM00490 277 363 1.3E-12 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_11215 93741ffa623be9fe30cb4b1e1eef9746 834 SMART SM00487 27 211 9.6E-16 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_11215 93741ffa623be9fe30cb4b1e1eef9746 834 Pfam PF00270 DEAD/DEAH box helicase 33 180 1.1E-9 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_14400 f74829f9b50b8970a88db36be6c7d438 253 Gene3D G3DSA:3.40.50.150 33 175 5.1E-14 T 12-10-2018 TL08_14400 f74829f9b50b8970a88db36be6c7d438 253 SUPERFAMILY SSF53335 15 235 5.36E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_14400 f74829f9b50b8970a88db36be6c7d438 253 Pfam PF12692 S-adenosyl-L-methionine methyltransferase 34 76 7.4E-4 T 12-10-2018 IPR025690 Methyltransferase, putative TL08_20430 77aabf33bf19c77c50640d441b2b8c27 158 PIRSF PIRSF000239 1 156 3.2E-17 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TL08_20430 77aabf33bf19c77c50640d441b2b8c27 158 SUPERFAMILY SSF52833 2 148 2.61E-41 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_20430 77aabf33bf19c77c50640d441b2b8c27 158 Gene3D G3DSA:3.40.30.10 1 150 1.5E-41 T 12-10-2018 TL08_20430 77aabf33bf19c77c50640d441b2b8c27 158 Pfam PF00578 AhpC/TSA family 4 125 5.1E-29 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TL08_08205 34d31eb23b04ca76c4cbfccb65724a5a 706 SMART SM00487 24 225 6.0E-22 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_08205 34d31eb23b04ca76c4cbfccb65724a5a 706 Gene3D G3DSA:3.40.50.300 5 216 1.6E-54 T 12-10-2018 TL08_08205 34d31eb23b04ca76c4cbfccb65724a5a 706 SMART SM00490 266 347 3.8E-21 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_08205 34d31eb23b04ca76c4cbfccb65724a5a 706 Pfam PF00271 Helicase conserved C-terminal domain 254 346 8.9E-13 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_08205 34d31eb23b04ca76c4cbfccb65724a5a 706 Pfam PF00270 DEAD/DEAH box helicase 31 200 1.5E-15 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_08205 34d31eb23b04ca76c4cbfccb65724a5a 706 SUPERFAMILY SSF52540 72 367 7.73E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08205 34d31eb23b04ca76c4cbfccb65724a5a 706 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 27 362 8.3E-70 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 TL08_08205 34d31eb23b04ca76c4cbfccb65724a5a 706 SUPERFAMILY SSF53271 581 702 1.42E-8 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_02290 8cd1c224578bc1326eecef29271f223a 250 SUPERFAMILY SSF53254 7 225 3.21E-69 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_02290 8cd1c224578bc1326eecef29271f223a 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 250 3.5E-110 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 TL08_02290 8cd1c224578bc1326eecef29271f223a 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 TL08_02290 8cd1c224578bc1326eecef29271f223a 250 PIRSF PIRSF000709 141 217 0.036 T 12-10-2018 TL08_02290 8cd1c224578bc1326eecef29271f223a 250 PIRSF PIRSF000709 5 115 0.0019 T 12-10-2018 TL08_02290 8cd1c224578bc1326eecef29271f223a 250 Gene3D G3DSA:3.40.50.1240 3 246 1.3E-80 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_02290 8cd1c224578bc1326eecef29271f223a 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 233 42.745 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 TL08_02290 8cd1c224578bc1326eecef29271f223a 250 SMART SM00855 7 192 4.7E-23 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_02290 8cd1c224578bc1326eecef29271f223a 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 131 3.5E-26 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_02290 8cd1c224578bc1326eecef29271f223a 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 146 210 1.2E-4 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_03535 8f715a76625650f5377221a7128865cd 260 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TL08_03535 8f715a76625650f5377221a7128865cd 260 Pfam PF01026 TatD related DNase 4 254 1.5E-70 T 12-10-2018 IPR001130 TatD family GO:0016788 TL08_03535 8f715a76625650f5377221a7128865cd 260 Gene3D G3DSA:3.20.20.140 1 257 2.2E-83 T 12-10-2018 TL08_03535 8f715a76625650f5377221a7128865cd 260 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 127 137 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TL08_03535 8f715a76625650f5377221a7128865cd 260 SUPERFAMILY SSF51556 3 256 7.43E-80 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_03535 8f715a76625650f5377221a7128865cd 260 PIRSF PIRSF005902 1 259 3.1E-73 T 12-10-2018 IPR001130 TatD family GO:0016788 TL08_03535 8f715a76625650f5377221a7128865cd 260 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 4 255 1.9E-79 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 TL08_15650 db7df68639a8ca24e0899756f97994dc 261 Gene3D G3DSA:1.10.10.10 4 81 3.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_15650 db7df68639a8ca24e0899756f97994dc 261 Pfam PF09339 IclR helix-turn-helix domain 13 61 2.0E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_15650 db7df68639a8ca24e0899756f97994dc 261 SMART SM00346 11 101 8.4E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_15650 db7df68639a8ca24e0899756f97994dc 261 SUPERFAMILY SSF46785 12 85 5.54E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_15650 db7df68639a8ca24e0899756f97994dc 261 Gene3D G3DSA:3.30.450.40 91 254 5.6E-36 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_15650 db7df68639a8ca24e0899756f97994dc 261 Pfam PF01614 Bacterial transcriptional regulator 129 248 4.2E-19 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_15650 db7df68639a8ca24e0899756f97994dc 261 SUPERFAMILY SSF55781 69 252 9.16E-34 T 12-10-2018 TL08_09295 0fb9011224794906528e45a7bf6333ca 472 Gene3D G3DSA:3.30.830.10 48 256 6.4E-70 T 12-10-2018 TL08_09295 0fb9011224794906528e45a7bf6333ca 472 Pfam PF05193 Peptidase M16 inactive domain 213 391 2.0E-39 T 12-10-2018 IPR007863 Peptidase M16, C-terminal TL08_09295 0fb9011224794906528e45a7bf6333ca 472 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 80 103 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 TL08_09295 0fb9011224794906528e45a7bf6333ca 472 SUPERFAMILY SSF63411 49 252 1.28E-58 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TL08_09295 0fb9011224794906528e45a7bf6333ca 472 Gene3D G3DSA:3.30.830.10 273 464 3.6E-46 T 12-10-2018 TL08_09295 0fb9011224794906528e45a7bf6333ca 472 Pfam PF00675 Insulinase (Peptidase family M16) 59 206 1.2E-37 T 12-10-2018 IPR011765 Peptidase M16, N-terminal TL08_09295 0fb9011224794906528e45a7bf6333ca 472 SUPERFAMILY SSF63411 278 461 1.48E-39 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TL08_23505 6852ca5df269ef189cfa93f74bff7231 576 Gene3D G3DSA:3.30.565.60 238 394 2.1E-33 T 12-10-2018 IPR038475 RecG, C-terminal domain superfamily TL08_23505 6852ca5df269ef189cfa93f74bff7231 576 SUPERFAMILY SSF46785 495 558 1.9E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23505 6852ca5df269ef189cfa93f74bff7231 576 Gene3D G3DSA:3.30.950.30 1 136 6.6E-30 T 12-10-2018 IPR038461 Schlafen, AAA domain superfamily TL08_23505 6852ca5df269ef189cfa93f74bff7231 576 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 307 391 5.5E-14 T 12-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain TL08_23505 6852ca5df269ef189cfa93f74bff7231 576 Pfam PF04326 Putative DNA-binding domain 21 136 8.8E-13 T 12-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 TL08_23505 6852ca5df269ef189cfa93f74bff7231 576 Gene3D G3DSA:1.10.10.10 499 554 2.8E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21035 21678aa9553d9f8eadc79c4c1e7aa39b 458 Pfam PF00589 Phage integrase family 243 437 2.4E-13 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_21035 21678aa9553d9f8eadc79c4c1e7aa39b 458 SUPERFAMILY SSF56349 173 438 2.18E-30 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_21035 21678aa9553d9f8eadc79c4c1e7aa39b 458 Gene3D G3DSA:1.10.150.130 134 236 1.7E-5 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_21035 21678aa9553d9f8eadc79c4c1e7aa39b 458 Gene3D G3DSA:1.10.443.10 240 453 5.8E-25 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TL08_16715 3d240446e2fc65907321ebfe39a8894b 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 6.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16715 3d240446e2fc65907321ebfe39a8894b 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 200 6.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16715 3d240446e2fc65907321ebfe39a8894b 313 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 6.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16715 3d240446e2fc65907321ebfe39a8894b 313 Gene3D G3DSA:3.40.50.720 5 309 1.7E-70 T 12-10-2018 TL08_16715 3d240446e2fc65907321ebfe39a8894b 313 SUPERFAMILY SSF51735 11 226 2.37E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16715 3d240446e2fc65907321ebfe39a8894b 313 Pfam PF00106 short chain dehydrogenase 15 222 6.7E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 5.0E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 5.0E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 5.0E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 5.0E-37 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.216 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 Gene3D G3DSA:3.90.1170.10 2 138 8.9E-49 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.7E-46 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.9E-53 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03020 e14161acc4f9ea12e3118e3dd8208786 139 SUPERFAMILY SSF54686 2 136 1.44E-53 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TL08_21240 812cb773778d432dbebae3055b1fd798 331 Pfam PF08281 Sigma-70, region 4 123 171 7.3E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_21240 812cb773778d432dbebae3055b1fd798 331 SUPERFAMILY SSF54427 185 330 1.05E-12 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_21240 812cb773778d432dbebae3055b1fd798 331 SUPERFAMILY SSF88946 11 94 2.04E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_21240 812cb773778d432dbebae3055b1fd798 331 Gene3D G3DSA:1.10.1740.10 2 78 1.1E-7 T 12-10-2018 TL08_21240 812cb773778d432dbebae3055b1fd798 331 Gene3D G3DSA:1.10.10.10 103 177 5.4E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21240 812cb773778d432dbebae3055b1fd798 331 Pfam PF04542 Sigma-70 region 2 15 80 3.9E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_21240 812cb773778d432dbebae3055b1fd798 331 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 172 5.4E-15 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_21240 812cb773778d432dbebae3055b1fd798 331 SUPERFAMILY SSF88659 119 173 1.61E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_21240 812cb773778d432dbebae3055b1fd798 331 Gene3D G3DSA:3.10.450.50 181 329 2.3E-6 T 12-10-2018 TL08_19090 690a9ad3cc22b1bc7188ca553622b162 294 Pfam PF00950 ABC 3 transport family 11 264 7.1E-63 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TL08_19090 690a9ad3cc22b1bc7188ca553622b162 294 SUPERFAMILY SSF81345 2 261 1.31E-34 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_19090 690a9ad3cc22b1bc7188ca553622b162 294 Gene3D G3DSA:1.10.3470.10 37 270 1.8E-6 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_11980 8e98d4653605d76da43b1f485356fbbb 273 PIRSF PIRSF006648 3 273 1.1E-64 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_11980 8e98d4653605d76da43b1f485356fbbb 273 Pfam PF01061 ABC-2 type transporter 25 228 4.4E-25 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_15430 af7ddf1ef3d48909681d0cb4022989f3 332 Gene3D G3DSA:3.40.190.10 90 185 3.4E-14 T 12-10-2018 TL08_15430 af7ddf1ef3d48909681d0cb4022989f3 332 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.6E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_15430 af7ddf1ef3d48909681d0cb4022989f3 332 Gene3D G3DSA:3.40.190.10 202 293 7.0E-12 T 12-10-2018 TL08_15430 af7ddf1ef3d48909681d0cb4022989f3 332 SUPERFAMILY SSF53850 89 325 2.9E-25 T 12-10-2018 TL08_15430 af7ddf1ef3d48909681d0cb4022989f3 332 SUPERFAMILY SSF46785 1 112 3.81E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_15430 af7ddf1ef3d48909681d0cb4022989f3 332 Pfam PF03466 LysR substrate binding domain 89 319 8.6E-30 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_15430 af7ddf1ef3d48909681d0cb4022989f3 332 Gene3D G3DSA:1.10.10.10 1 89 3.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26350 361b232ee743f895e6c1f8fa3f93dcb1 197 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 197 24.642 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_26350 361b232ee743f895e6c1f8fa3f93dcb1 197 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 31 193 2.4E-35 T 12-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TL08_26350 361b232ee743f895e6c1f8fa3f93dcb1 197 Gene3D G3DSA:3.40.50.2020 13 197 7.7E-51 T 12-10-2018 TL08_26350 361b232ee743f895e6c1f8fa3f93dcb1 197 SUPERFAMILY SSF53271 20 193 3.15E-36 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_26350 361b232ee743f895e6c1f8fa3f93dcb1 197 Pfam PF00156 Phosphoribosyl transferase domain 59 176 1.1E-14 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SUPERFAMILY SSF48452 706 901 6.16E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Pfam PF13374 Tetratricopeptide repeat 874 903 1.9E-4 T 12-10-2018 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Gene3D G3DSA:1.25.40.10 104 268 2.8E-36 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Pfam PF13424 Tetratricopeptide repeat 793 863 2.3E-14 T 12-10-2018 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Pfam PF13424 Tetratricopeptide repeat 711 782 1.3E-9 T 12-10-2018 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Pfam PF13424 Tetratricopeptide repeat 909 982 6.3E-11 T 12-10-2018 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Gene3D G3DSA:1.10.10.10 6 100 1.9E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Pfam PF00486 Transcriptional regulatory protein, C terminal 31 98 1.4E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Pfam PF00931 NB-ARC domain 281 471 6.9E-9 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SMART SM00862 21 98 2.8E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Gene3D G3DSA:1.25.40.10 648 905 8.6E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SUPERFAMILY SSF48452 104 266 3.79E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 PRINTS PR00364 Disease resistance protein signature 296 311 1.2E-5 T 12-10-2018 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 PRINTS PR00364 Disease resistance protein signature 462 476 1.2E-5 T 12-10-2018 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 PRINTS PR00364 Disease resistance protein signature 374 388 1.2E-5 T 12-10-2018 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Gene3D G3DSA:1.25.40.10 906 996 7.2E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SUPERFAMILY SSF48452 866 989 2.78E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SMART SM01043 105 246 5.2E-36 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SUPERFAMILY SSF46894 25 98 8.22E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 Pfam PF03704 Bacterial transcriptional activator domain 105 246 6.4E-29 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SMART SM00028 751 784 0.39 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SMART SM00028 910 943 0.31 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SMART SM00028 791 824 6.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SMART SM00028 871 904 0.015 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SMART SM00028 950 983 34.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SMART SM00028 831 864 2.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SMART SM00028 711 744 200.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_12340 2f374cda74e901356a2b231b034c9ea9 1010 SUPERFAMILY SSF52540 260 529 2.66E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 252 390 7.5E-65 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 12 401 1.7E-164 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 SUPERFAMILY SSF55973 252 401 2.04E-65 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 SUPERFAMILY SSF55973 127 251 3.18E-44 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 Gene3D G3DSA:3.30.300.10 12 252 1.1E-166 T 12-10-2018 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 PIRSF PIRSF000497 5 403 1.4E-162 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 SUPERFAMILY SSF55973 10 116 8.24E-45 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 9 402 55.109 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 278 286 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 Gene3D G3DSA:3.30.300.10 109 393 1.1E-166 T 12-10-2018 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 Gene3D G3DSA:3.30.300.10 18 289 1.1E-166 T 12-10-2018 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 Pfam PF02772 S-adenosylmethionine synthetase, central domain 132 250 3.6E-43 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 133 143 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_11530 1da2626c0de770a577d8f5fbfa69133c 404 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 11 108 2.1E-40 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TL08_04325 3a2aefa75e0e7fc79bc9739a68721fd5 436 Pfam PF00463 Isocitrate lyase family 23 260 4.5E-57 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TL08_04325 3a2aefa75e0e7fc79bc9739a68721fd5 436 Pfam PF00463 Isocitrate lyase family 261 430 1.9E-44 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TL08_04325 3a2aefa75e0e7fc79bc9739a68721fd5 436 PIRSF PIRSF001362 10 436 2.4E-228 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TL08_04325 3a2aefa75e0e7fc79bc9739a68721fd5 436 SUPERFAMILY SSF51621 16 436 6.28E-151 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TL08_04325 3a2aefa75e0e7fc79bc9739a68721fd5 436 Gene3D G3DSA:3.20.20.60 15 420 1.0E-166 T 12-10-2018 TL08_04325 3a2aefa75e0e7fc79bc9739a68721fd5 436 ProSitePatterns PS00161 Isocitrate lyase signature. 198 203 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 TL08_04325 3a2aefa75e0e7fc79bc9739a68721fd5 436 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 17 260 1.3E-106 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TL08_25565 f65b810a0f59e13de482905c64fcc15c 123 Pfam PF01638 HxlR-like helix-turn-helix 16 103 8.5E-32 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_25565 f65b810a0f59e13de482905c64fcc15c 123 Gene3D G3DSA:1.10.10.10 3 115 1.6E-41 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25565 f65b810a0f59e13de482905c64fcc15c 123 SUPERFAMILY SSF46785 5 106 1.16E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_09140 3747e8d426699758dccf5a009b74c24d 161 Pfam PF01894 Uncharacterised protein family UPF0047 38 156 2.0E-21 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 TL08_09140 3747e8d426699758dccf5a009b74c24d 161 SUPERFAMILY SSF111038 23 157 2.22E-29 T 12-10-2018 IPR035917 YjbQ-like superfamily TL08_09140 3747e8d426699758dccf5a009b74c24d 161 Gene3D G3DSA:2.60.120.460 22 160 1.6E-26 T 12-10-2018 IPR035917 YjbQ-like superfamily TL08_22905 a89972621b8a075c4b6f70dff55b3f79 164 SUPERFAMILY SSF50475 11 98 1.12E-15 T 12-10-2018 TL08_22905 a89972621b8a075c4b6f70dff55b3f79 164 Gene3D G3DSA:2.30.110.10 1 123 2.7E-16 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_22905 a89972621b8a075c4b6f70dff55b3f79 164 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 90 1.8E-11 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_20640 9ae5069c92c2a17a394447a8b5e8dada 361 Pfam PF13378 Enolase C-terminal domain-like 145 350 5.0E-54 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_20640 9ae5069c92c2a17a394447a8b5e8dada 361 Gene3D G3DSA:3.30.390.10 21 115 1.5E-96 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_20640 9ae5069c92c2a17a394447a8b5e8dada 361 SUPERFAMILY SSF54826 1 125 2.02E-26 T 12-10-2018 TL08_20640 9ae5069c92c2a17a394447a8b5e8dada 361 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 189 220 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TL08_20640 9ae5069c92c2a17a394447a8b5e8dada 361 Gene3D G3DSA:3.20.20.120 116 350 1.5E-96 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_20640 9ae5069c92c2a17a394447a8b5e8dada 361 SUPERFAMILY SSF51604 111 356 3.41E-62 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_20640 9ae5069c92c2a17a394447a8b5e8dada 361 SMART SM00922 142 239 1.1E-23 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_20640 9ae5069c92c2a17a394447a8b5e8dada 361 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 123 5.1E-13 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TL08_00285 d2e05c74e8fffc43515e942131812a58 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 194 0.0046 T 12-10-2018 TL08_00285 d2e05c74e8fffc43515e942131812a58 253 Gene3D G3DSA:3.40.50.720 1 253 6.2E-68 T 12-10-2018 TL08_00285 d2e05c74e8fffc43515e942131812a58 253 SUPERFAMILY SSF51735 7 249 1.3E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_00285 d2e05c74e8fffc43515e942131812a58 253 Pfam PF00106 short chain dehydrogenase 7 201 2.2E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 4.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00285 d2e05c74e8fffc43515e942131812a58 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_11930 b0bbcce846df2fe2ef1e0d2c5cfa0797 433 Pfam PF13520 Amino acid permease 20 427 5.8E-35 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TL08_11930 b0bbcce846df2fe2ef1e0d2c5cfa0797 433 PIRSF PIRSF006060 1 426 5.7E-64 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TL08_11930 b0bbcce846df2fe2ef1e0d2c5cfa0797 433 Gene3D G3DSA:1.20.1740.10 15 432 1.7E-74 T 12-10-2018 TL08_13205 810b49e34aabdd3bc097b15ea72a9625 278 SUPERFAMILY SSF159659 1 243 5.49E-83 T 12-10-2018 TL08_13205 810b49e34aabdd3bc097b15ea72a9625 278 Gene3D G3DSA:3.40.50.10900 1 202 6.6E-88 T 12-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TL08_13205 810b49e34aabdd3bc097b15ea72a9625 278 PIRSF PIRSF028754 1 272 6.4E-101 T 12-10-2018 IPR008492 Protein of unknown function DUF774 TL08_13205 810b49e34aabdd3bc097b15ea72a9625 278 Gene3D G3DSA:1.10.287.100 203 241 6.6E-88 T 12-10-2018 TL08_13205 810b49e34aabdd3bc097b15ea72a9625 278 Pfam PF09754 PAC2 family 4 222 2.7E-48 T 12-10-2018 IPR019151 Proteasome assembly chaperone 2 TL08_25750 1a55d0a5e734c50294c86b3b75d4dd62 275 SUPERFAMILY SSF140959 20 273 6.28E-71 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 TL08_25750 1a55d0a5e734c50294c86b3b75d4dd62 275 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 14 275 34.099 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 TL08_25750 1a55d0a5e734c50294c86b3b75d4dd62 275 Pfam PF03301 Tryptophan 2,3-dioxygenase 11 174 2.2E-35 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 TL08_25750 1a55d0a5e734c50294c86b3b75d4dd62 275 Pfam PF03301 Tryptophan 2,3-dioxygenase 202 273 1.2E-21 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 TL08_25750 1a55d0a5e734c50294c86b3b75d4dd62 275 Gene3D G3DSA:1.20.58.480 19 275 1.0E-67 T 12-10-2018 TL08_07235 41b4e3a677117191269d23a69945aeff 474 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 55 473 37.841 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_07235 41b4e3a677117191269d23a69945aeff 474 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 270 287 - T 12-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site TL08_07235 41b4e3a677117191269d23a69945aeff 474 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 339 430 1.2E-14 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 TL08_07235 41b4e3a677117191269d23a69945aeff 474 Gene3D G3DSA:3.20.20.10 74 334 1.8E-162 T 12-10-2018 IPR029066 PLP-binding barrel TL08_07235 41b4e3a677117191269d23a69945aeff 474 SUPERFAMILY SSF50621 308 473 8.16E-45 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TL08_07235 41b4e3a677117191269d23a69945aeff 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 203 212 3.2E-23 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_07235 41b4e3a677117191269d23a69945aeff 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 440 462 3.2E-23 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_07235 41b4e3a677117191269d23a69945aeff 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 114 131 3.2E-23 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_07235 41b4e3a677117191269d23a69945aeff 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 357 375 3.2E-23 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_07235 41b4e3a677117191269d23a69945aeff 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 96 114 5.5E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TL08_07235 41b4e3a677117191269d23a69945aeff 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 231 244 5.5E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TL08_07235 41b4e3a677117191269d23a69945aeff 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 116 128 5.5E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TL08_07235 41b4e3a677117191269d23a69945aeff 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 430 443 5.5E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TL08_07235 41b4e3a677117191269d23a69945aeff 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 324 343 5.5E-17 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TL08_07235 41b4e3a677117191269d23a69945aeff 474 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 75 334 4.7E-63 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TL08_07235 41b4e3a677117191269d23a69945aeff 474 SUPERFAMILY SSF51419 66 335 1.6E-73 T 12-10-2018 IPR029066 PLP-binding barrel TL08_07235 41b4e3a677117191269d23a69945aeff 474 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 46 473 1.3E-139 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_07235 41b4e3a677117191269d23a69945aeff 474 Gene3D G3DSA:2.40.37.10 54 469 1.8E-162 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TL08_07235 41b4e3a677117191269d23a69945aeff 474 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 96 114 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site TL08_08605 7fa9833c09e2908ad741f41fa051b59a 520 Gene3D G3DSA:2.60.40.290 414 520 1.1E-33 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 TL08_08605 7fa9833c09e2908ad741f41fa051b59a 520 Pfam PF07995 Glucose / Sorbosone dehydrogenase 63 405 8.8E-48 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TL08_08605 7fa9833c09e2908ad741f41fa051b59a 520 Pfam PF00553 Cellulose binding domain 419 519 4.6E-28 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TL08_08605 7fa9833c09e2908ad741f41fa051b59a 520 Gene3D G3DSA:2.120.10.30 48 409 5.3E-88 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_08605 7fa9833c09e2908ad741f41fa051b59a 520 SUPERFAMILY SSF50952 55 408 4.18E-32 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TL08_08605 7fa9833c09e2908ad741f41fa051b59a 520 SUPERFAMILY SSF49384 414 519 1.19E-31 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 TL08_08605 7fa9833c09e2908ad741f41fa051b59a 520 SMART SM00637 419 519 1.2E-37 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TL08_13385 9bec0b8290e4d5e60bdb4b62cc2bcfa3 661 Pfam PF07555 beta-N-acetylglucosaminidase 201 511 7.9E-106 T 12-10-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 TL08_13385 9bec0b8290e4d5e60bdb4b62cc2bcfa3 661 Gene3D G3DSA:3.30.379.10 46 195 5.3E-27 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 TL08_13385 9bec0b8290e4d5e60bdb4b62cc2bcfa3 661 Gene3D G3DSA:1.20.58.460 530 658 3.4E-10 T 12-10-2018 TL08_13385 9bec0b8290e4d5e60bdb4b62cc2bcfa3 661 Gene3D G3DSA:3.20.20.80 197 518 3.5E-108 T 12-10-2018 TL08_13385 9bec0b8290e4d5e60bdb4b62cc2bcfa3 661 SUPERFAMILY SSF55545 58 196 1.31E-16 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 TL08_13385 9bec0b8290e4d5e60bdb4b62cc2bcfa3 661 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 58 194 1.5E-18 T 12-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal TL08_13385 9bec0b8290e4d5e60bdb4b62cc2bcfa3 661 SUPERFAMILY SSF51445 199 526 6.11E-103 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_01450 2c14644e5dbda570fe8243a982c76661 382 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 33 371 1.8E-99 T 12-10-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like TL08_01450 2c14644e5dbda570fe8243a982c76661 382 SUPERFAMILY SSF52172 21 136 3.83E-6 T 12-10-2018 IPR011006 CheY-like superfamily TL08_01450 2c14644e5dbda570fe8243a982c76661 382 Pfam PF06564 Cellulose biosynthesis protein BcsQ 143 290 4.7E-5 T 12-10-2018 IPR017746 Cellulose synthase operon protein BcsQ TL08_01450 2c14644e5dbda570fe8243a982c76661 382 SUPERFAMILY SSF52540 141 374 3.36E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01450 2c14644e5dbda570fe8243a982c76661 382 Gene3D G3DSA:3.40.50.300 142 375 4.6E-23 T 12-10-2018 TL08_14060 0f32df11d305e69f215f99ec88ee4cf5 205 Gene3D G3DSA:1.20.120.680 1 204 1.8E-41 T 12-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 TL08_14060 0f32df11d305e69f215f99ec88ee4cf5 205 SUPERFAMILY SSF101262 3 196 5.62E-31 T 12-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 TL08_14060 0f32df11d305e69f215f99ec88ee4cf5 205 Pfam PF04961 Formiminotransferase-cyclodeaminase 5 183 3.3E-36 T 12-10-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 TL08_00295 e1a39e7aa74988651c22e26f6ba1a74f 180 Gene3D G3DSA:3.10.450.40 91 159 2.9E-16 T 12-10-2018 TL08_00295 e1a39e7aa74988651c22e26f6ba1a74f 180 Pfam PF03413 Peptidase propeptide and YPEB domain 98 155 4.6E-15 T 12-10-2018 IPR025711 PepSY domain TL08_11455 941a76a2339747d06d1d702cd104e23a 373 Pfam PF00557 Metallopeptidase family M24 153 356 1.5E-61 T 12-10-2018 IPR000994 Peptidase M24 TL08_11455 941a76a2339747d06d1d702cd104e23a 373 SUPERFAMILY SSF53092 10 144 2.27E-22 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TL08_11455 941a76a2339747d06d1d702cd104e23a 373 Gene3D G3DSA:3.40.350.10 11 144 3.3E-27 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TL08_11455 941a76a2339747d06d1d702cd104e23a 373 Pfam PF01321 Creatinase/Prolidase N-terminal domain 12 145 8.3E-23 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TL08_11455 941a76a2339747d06d1d702cd104e23a 373 Gene3D G3DSA:3.90.230.10 145 373 3.4E-77 T 12-10-2018 TL08_11455 941a76a2339747d06d1d702cd104e23a 373 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 303 315 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TL08_11455 941a76a2339747d06d1d702cd104e23a 373 SUPERFAMILY SSF55920 105 367 2.88E-73 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TL08_11455 941a76a2339747d06d1d702cd104e23a 373 PRINTS PR00599 Methionine aminopeptidase-1 signature 205 218 6.8E-8 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_11455 941a76a2339747d06d1d702cd104e23a 373 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 243 6.8E-8 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_11455 941a76a2339747d06d1d702cd104e23a 373 PRINTS PR00599 Methionine aminopeptidase-1 signature 325 337 6.8E-8 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TL08_19130 c6c213bf774fe36f5f6a956e773c0e27 86 Pfam PF00355 Rieske [2Fe-2S] domain 6 76 2.1E-8 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TL08_19130 c6c213bf774fe36f5f6a956e773c0e27 86 Gene3D G3DSA:2.102.10.10 1 84 6.5E-13 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_19130 c6c213bf774fe36f5f6a956e773c0e27 86 SUPERFAMILY SSF50022 7 79 1.11E-12 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_15800 c04cb971447ddba45dbbb444becefc5f 86 Gene3D G3DSA:1.10.1200.10 4 84 6.6E-6 T 12-10-2018 IPR036736 ACP-like superfamily TL08_15800 c04cb971447ddba45dbbb444becefc5f 86 SUPERFAMILY SSF47336 10 65 8.64E-6 T 12-10-2018 IPR036736 ACP-like superfamily TL08_20175 c85d414ae937d03797bbc39c9022d2ad 448 Gene3D G3DSA:3.90.1150.10 310 448 4.0E-51 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_20175 c85d414ae937d03797bbc39c9022d2ad 448 PIRSF PIRSF001434 13 445 9.4E-131 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TL08_20175 c85d414ae937d03797bbc39c9022d2ad 448 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 25 441 1.8E-140 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TL08_20175 c85d414ae937d03797bbc39c9022d2ad 448 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 218 232 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TL08_20175 c85d414ae937d03797bbc39c9022d2ad 448 Gene3D G3DSA:3.40.640.10 23 306 3.5E-103 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_20175 c85d414ae937d03797bbc39c9022d2ad 448 SUPERFAMILY SSF53383 22 441 6.12E-121 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_20175 c85d414ae937d03797bbc39c9022d2ad 448 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 24 441 2.1E-196 T 12-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 TL08_03045 c8de9ec2c90820e86cfb98d088ee9ed1 191 SUPERFAMILY SSF55282 10 185 1.7E-70 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03045 c8de9ec2c90820e86cfb98d088ee9ed1 191 PIRSF PIRSF002161 5 191 1.1E-59 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03045 c8de9ec2c90820e86cfb98d088ee9ed1 191 Pfam PF00281 Ribosomal protein L5 31 87 4.9E-26 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03045 c8de9ec2c90820e86cfb98d088ee9ed1 191 Pfam PF00673 ribosomal L5P family C-terminus 91 184 1.8E-36 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03045 c8de9ec2c90820e86cfb98d088ee9ed1 191 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 42.086 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03045 c8de9ec2c90820e86cfb98d088ee9ed1 191 Gene3D G3DSA:3.30.1440.10 6 186 1.6E-73 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_12200 44a340fa7b993adbcb6487840ffcd9c5 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 192 1.1E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_12200 44a340fa7b993adbcb6487840ffcd9c5 200 Pfam PF08281 Sigma-70, region 4 138 189 2.1E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_12200 44a340fa7b993adbcb6487840ffcd9c5 200 SUPERFAMILY SSF88659 134 193 4.14E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_12200 44a340fa7b993adbcb6487840ffcd9c5 200 Gene3D G3DSA:1.10.1740.10 14 102 3.5E-27 T 12-10-2018 TL08_12200 44a340fa7b993adbcb6487840ffcd9c5 200 Pfam PF04542 Sigma-70 region 2 41 106 7.2E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_12200 44a340fa7b993adbcb6487840ffcd9c5 200 SUPERFAMILY SSF88946 22 118 2.2E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_12200 44a340fa7b993adbcb6487840ffcd9c5 200 Gene3D G3DSA:1.10.10.10 131 197 9.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_13250 ff28007f8ede7f29fcb3182eb429a3ed 517 SUPERFAMILY SSF103473 4 507 1.02E-56 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_13250 ff28007f8ede7f29fcb3182eb429a3ed 517 PRINTS PR01036 Tetracycline resistance protein TetB signature 406 425 5.6E-7 T 12-10-2018 TL08_13250 ff28007f8ede7f29fcb3182eb429a3ed 517 PRINTS PR01036 Tetracycline resistance protein TetB signature 80 102 5.6E-7 T 12-10-2018 TL08_13250 ff28007f8ede7f29fcb3182eb429a3ed 517 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 5.6E-7 T 12-10-2018 TL08_13250 ff28007f8ede7f29fcb3182eb429a3ed 517 PRINTS PR01036 Tetracycline resistance protein TetB signature 364 384 5.6E-7 T 12-10-2018 TL08_13250 ff28007f8ede7f29fcb3182eb429a3ed 517 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 5.6E-7 T 12-10-2018 TL08_13250 ff28007f8ede7f29fcb3182eb429a3ed 517 Gene3D G3DSA:1.20.1250.20 269 510 7.1E-13 T 12-10-2018 TL08_13250 ff28007f8ede7f29fcb3182eb429a3ed 517 Pfam PF07690 Major Facilitator Superfamily 25 415 1.0E-40 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_13250 ff28007f8ede7f29fcb3182eb429a3ed 517 Gene3D G3DSA:1.20.1720.10 18 229 6.6E-39 T 12-10-2018 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 Pfam PF00672 HAMP domain 230 279 5.7E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 Gene3D G3DSA:1.20.1480.50 197 284 7.0E-15 T 12-10-2018 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 Gene3D G3DSA:1.10.287.130 285 361 2.4E-15 T 12-10-2018 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 Gene3D G3DSA:3.30.565.10 362 513 3.4E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 SUPERFAMILY SSF47384 273 357 1.1E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 SUPERFAMILY SSF55874 347 519 1.96E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 SMART SM00387 403 514 4.8E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 SMART SM00304 230 282 6.4E-15 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 SUPERFAMILY SSF158472 230 281 9.29E-10 T 12-10-2018 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 Pfam PF00512 His Kinase A (phospho-acceptor) domain 291 357 5.2E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 467 6.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 492 6.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 511 6.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 453 6.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 404 513 7.5E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_23290 a0a8804ab7733676a69a36fc86f8da1c 609 SMART SM00388 290 357 9.6E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_00700 100062ba8dd0a34983e51b548fe93f69 394 SUPERFAMILY SSF54373 253 324 2.35E-22 T 12-10-2018 TL08_00700 100062ba8dd0a34983e51b548fe93f69 394 Gene3D G3DSA:3.40.50.720 3 103 2.5E-33 T 12-10-2018 TL08_00700 100062ba8dd0a34983e51b548fe93f69 394 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 6 378 2.5E-105 T 12-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TL08_00700 100062ba8dd0a34983e51b548fe93f69 394 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 79 2.2E-17 T 12-10-2018 TL08_00700 100062ba8dd0a34983e51b548fe93f69 394 Pfam PF03275 UDP-galactopyranose mutase 154 360 1.8E-80 T 12-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TL08_00700 100062ba8dd0a34983e51b548fe93f69 394 SUPERFAMILY SSF51971 6 374 1.82E-46 T 12-10-2018 TL08_00700 100062ba8dd0a34983e51b548fe93f69 394 Gene3D G3DSA:3.40.50.720 141 263 2.9E-25 T 12-10-2018 TL08_00700 100062ba8dd0a34983e51b548fe93f69 394 Gene3D G3DSA:3.40.50.720 305 385 7.9E-20 T 12-10-2018 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 Gene3D G3DSA:3.40.1380.10 61 225 1.3E-92 T 12-10-2018 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 306 34.833 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 306 3.6E-100 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 Gene3D G3DSA:1.10.287.80 7 302 1.3E-92 T 12-10-2018 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 PRINTS PR00126 ATP synthase gamma subunit signature 253 272 8.2E-35 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 8.2E-35 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 PRINTS PR00126 ATP synthase gamma subunit signature 181 198 8.2E-35 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 PRINTS PR00126 ATP synthase gamma subunit signature 284 305 8.2E-35 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 Pfam PF00231 ATP synthase 5 306 4.8E-90 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07330 b0ead1ccb91811645116b010f4151fa2 313 SUPERFAMILY SSF52943 3 306 9.94E-80 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_10095 e85e59b071341498e317aa3a1d394abb 139 Gene3D G3DSA:2.20.25.10 1 45 3.7E-14 T 12-10-2018 TL08_10095 e85e59b071341498e317aa3a1d394abb 139 Gene3D G3DSA:3.30.300.20 46 137 6.7E-31 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_10095 e85e59b071341498e317aa3a1d394abb 139 SUPERFAMILY SSF82784 1 137 2.75E-36 T 12-10-2018 IPR036102 OsmC/Ohr superfamily TL08_10095 e85e59b071341498e317aa3a1d394abb 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 136 1.8E-49 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 TL08_10095 e85e59b071341498e317aa3a1d394abb 139 Pfam PF02566 OsmC-like protein 39 134 6.8E-18 T 12-10-2018 IPR003718 OsmC/Ohr family TL08_01420 1cd6b6452765ff8fad199657aa6758e7 271 Pfam PF14011 EspG family 12 262 1.4E-45 T 12-10-2018 IPR025734 EspG family TL08_05350 a2cad887c5fc882bf89e0b501a806bf3 345 SUPERFAMILY SSF51430 2 312 4.32E-95 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_05350 a2cad887c5fc882bf89e0b501a806bf3 345 Pfam PF00248 Aldo/keto reductase family 18 311 4.4E-69 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_05350 a2cad887c5fc882bf89e0b501a806bf3 345 PRINTS PR00069 Aldo-keto reductase signature 106 124 3.4E-11 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_05350 a2cad887c5fc882bf89e0b501a806bf3 345 PRINTS PR00069 Aldo-keto reductase signature 137 154 3.4E-11 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_05350 a2cad887c5fc882bf89e0b501a806bf3 345 PRINTS PR00069 Aldo-keto reductase signature 41 65 3.4E-11 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_05350 a2cad887c5fc882bf89e0b501a806bf3 345 Gene3D G3DSA:3.20.20.100 1 317 2.6E-111 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_24595 c6991aba4ffe83e990197939067126fb 392 PIRSF PIRSF001554 1 391 1.3E-138 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TL08_24595 c6991aba4ffe83e990197939067126fb 392 Gene3D G3DSA:3.30.1490.20 21 96 2.2E-81 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TL08_24595 c6991aba4ffe83e990197939067126fb 392 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 389 38.924 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TL08_24595 c6991aba4ffe83e990197939067126fb 392 Pfam PF00549 CoA-ligase 256 368 5.4E-13 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_24595 c6991aba4ffe83e990197939067126fb 392 Pfam PF08442 ATP-grasp domain 2 194 4.0E-72 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TL08_24595 c6991aba4ffe83e990197939067126fb 392 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 388 1.1E-129 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TL08_24595 c6991aba4ffe83e990197939067126fb 392 SUPERFAMILY SSF52210 231 388 1.22E-40 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_24595 c6991aba4ffe83e990197939067126fb 392 Gene3D G3DSA:3.40.50.261 232 390 2.4E-45 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_24595 c6991aba4ffe83e990197939067126fb 392 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_24595 c6991aba4ffe83e990197939067126fb 392 SUPERFAMILY SSF56059 3 228 2.12E-71 T 12-10-2018 TL08_24595 c6991aba4ffe83e990197939067126fb 392 Gene3D G3DSA:3.30.470.20 3 220 2.2E-81 T 12-10-2018 TL08_23080 90927dddafab896a5b998278e869c0f5 510 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 140 156 - T 12-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 TL08_23080 90927dddafab896a5b998278e869c0f5 510 SUPERFAMILY SSF48557 3 505 1.02E-176 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 TL08_23080 90927dddafab896a5b998278e869c0f5 510 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 7 508 4.2E-194 T 12-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23080 90927dddafab896a5b998278e869c0f5 510 Pfam PF00221 Aromatic amino acid lyase 12 473 1.7E-177 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 TL08_23080 90927dddafab896a5b998278e869c0f5 510 Gene3D G3DSA:1.10.275.10 2 199 2.3E-65 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal TL08_23080 90927dddafab896a5b998278e869c0f5 510 Gene3D G3DSA:1.20.200.10 200 510 6.2E-110 T 12-10-2018 TL08_10860 83fe6b70d6ade50723ba5df0c12346d5 297 Gene3D G3DSA:3.40.190.10 93 281 5.8E-44 T 12-10-2018 TL08_10860 83fe6b70d6ade50723ba5df0c12346d5 297 SUPERFAMILY SSF46785 1 112 5.23E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_10860 83fe6b70d6ade50723ba5df0c12346d5 297 Gene3D G3DSA:1.10.10.10 1 92 2.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_10860 83fe6b70d6ade50723ba5df0c12346d5 297 SUPERFAMILY SSF53850 90 296 7.97E-41 T 12-10-2018 TL08_10860 83fe6b70d6ade50723ba5df0c12346d5 297 Pfam PF03466 LysR substrate binding domain 88 295 2.7E-44 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_10860 83fe6b70d6ade50723ba5df0c12346d5 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.7E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_10860 83fe6b70d6ade50723ba5df0c12346d5 297 Gene3D G3DSA:3.40.190.10 167 269 5.8E-44 T 12-10-2018 TL08_24355 fd205ee4c27315d18df40d04ac1ed446 110 SUPERFAMILY SSF46785 16 94 7.37E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_24355 fd205ee4c27315d18df40d04ac1ed446 110 Pfam PF13601 Winged helix DNA-binding domain 17 94 1.2E-14 T 12-10-2018 IPR027395 Winged helix DNA-binding domain TL08_24355 fd205ee4c27315d18df40d04ac1ed446 110 Gene3D G3DSA:1.10.10.10 7 96 1.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_02555 1dd8ec46479489ab00359af92b1368fc 253 Gene3D G3DSA:3.30.540.10 12 143 2.3E-18 T 12-10-2018 TL08_02555 1dd8ec46479489ab00359af92b1368fc 253 SUPERFAMILY SSF56655 14 247 2.49E-29 T 12-10-2018 TL08_02555 1dd8ec46479489ab00359af92b1368fc 253 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 7.6E-6 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_02555 1dd8ec46479489ab00359af92b1368fc 253 PRINTS PR00377 Inositol monophosphatase superfamily signature 200 224 7.6E-6 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_02555 1dd8ec46479489ab00359af92b1368fc 253 PRINTS PR00377 Inositol monophosphatase superfamily signature 47 67 7.6E-6 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_02555 1dd8ec46479489ab00359af92b1368fc 253 Pfam PF00459 Inositol monophosphatase family 19 233 8.2E-17 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TL08_02555 1dd8ec46479489ab00359af92b1368fc 253 Gene3D G3DSA:3.40.190.80 144 248 3.0E-7 T 12-10-2018 TL08_14800 6ee88828c555278d37f37666f10bdf8d 331 Gene3D G3DSA:1.10.3720.10 99 320 4.1E-20 T 12-10-2018 IPR035906 MetI-like superfamily TL08_14800 6ee88828c555278d37f37666f10bdf8d 331 SUPERFAMILY SSF161098 109 310 8.76E-17 T 12-10-2018 IPR035906 MetI-like superfamily TL08_14800 6ee88828c555278d37f37666f10bdf8d 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 328 1.6E-37 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_11385 7eed3b0bdf34a222fc49dd06db0967ad 90 PRINTS PR00107 Phosphocarrier protein signature 40 55 9.5E-12 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_11385 7eed3b0bdf34a222fc49dd06db0967ad 90 PRINTS PR00107 Phosphocarrier protein signature 55 72 9.5E-12 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_11385 7eed3b0bdf34a222fc49dd06db0967ad 90 PRINTS PR00107 Phosphocarrier protein signature 13 29 9.5E-12 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_11385 7eed3b0bdf34a222fc49dd06db0967ad 90 Pfam PF00381 PTS HPr component phosphorylation site 3 84 1.5E-22 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_11385 7eed3b0bdf34a222fc49dd06db0967ad 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 1.3E-21 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like TL08_11385 7eed3b0bdf34a222fc49dd06db0967ad 90 SUPERFAMILY SSF55594 1 88 2.75E-19 T 12-10-2018 IPR035895 HPr-like superfamily TL08_11385 7eed3b0bdf34a222fc49dd06db0967ad 90 Gene3D G3DSA:3.30.1340.10 1 90 3.8E-22 T 12-10-2018 IPR035895 HPr-like superfamily TL08_11385 7eed3b0bdf34a222fc49dd06db0967ad 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TL08_15020 00895c7efba08c786c7e3c3d9782610c 330 Gene3D G3DSA:1.10.260.40 1 55 8.9E-22 T 12-10-2018 TL08_15020 00895c7efba08c786c7e3c3d9782610c 330 SMART SM00354 1 68 4.3E-24 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_15020 00895c7efba08c786c7e3c3d9782610c 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 5.2E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_15020 00895c7efba08c786c7e3c3d9782610c 330 Gene3D G3DSA:3.40.50.2300 75 314 6.3E-66 T 12-10-2018 TL08_15020 00895c7efba08c786c7e3c3d9782610c 330 SUPERFAMILY SSF47413 1 54 2.19E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_15020 00895c7efba08c786c7e3c3d9782610c 330 SUPERFAMILY SSF53822 57 327 1.85E-56 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_15020 00895c7efba08c786c7e3c3d9782610c 330 Pfam PF13377 Periplasmic binding protein-like domain 165 323 3.8E-38 T 12-10-2018 TL08_15020 00895c7efba08c786c7e3c3d9782610c 330 Gene3D G3DSA:3.40.50.2300 156 317 6.3E-66 T 12-10-2018 TL08_14325 e1cb9512f7cf3e0fa8a71e722bafc321 127 Gene3D G3DSA:1.10.260.40 7 70 3.3E-6 T 12-10-2018 TL08_14325 e1cb9512f7cf3e0fa8a71e722bafc321 127 SUPERFAMILY SSF47413 8 68 6.29E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_26845 0f615fb663d41554b0e771a2a524746e 167 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 31.305 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TL08_26845 0f615fb663d41554b0e771a2a524746e 167 Pfam PF00436 Single-strand binding protein family 6 106 1.4E-28 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TL08_26845 0f615fb663d41554b0e771a2a524746e 167 Gene3D G3DSA:2.40.50.140 1 120 1.3E-42 T 12-10-2018 TL08_26845 0f615fb663d41554b0e771a2a524746e 167 SUPERFAMILY SSF50249 6 167 1.05E-45 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_26845 0f615fb663d41554b0e771a2a524746e 167 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 126 1.6E-32 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TL08_10955 a662503a7628f0a1f65887f3b11f301e 470 ProSitePatterns PS00571 Amidases signature. 155 186 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TL08_10955 a662503a7628f0a1f65887f3b11f301e 470 Gene3D G3DSA:3.90.1300.10 2 467 4.0E-147 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_10955 a662503a7628f0a1f65887f3b11f301e 470 SUPERFAMILY SSF75304 5 465 6.54E-134 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_10955 a662503a7628f0a1f65887f3b11f301e 470 Pfam PF01425 Amidase 28 447 1.1E-103 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_06680 1d57af5d61763629904f70a2c6d0e052 319 Gene3D G3DSA:3.40.50.620 1 180 2.5E-35 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_06680 1d57af5d61763629904f70a2c6d0e052 319 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 195 277 1.2E-34 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 TL08_06680 1d57af5d61763629904f70a2c6d0e052 319 Pfam PF01012 Electron transfer flavoprotein domain 4 172 7.4E-27 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TL08_06680 1d57af5d61763629904f70a2c6d0e052 319 SUPERFAMILY SSF52402 4 182 1.09E-38 T 12-10-2018 TL08_06680 1d57af5d61763629904f70a2c6d0e052 319 SUPERFAMILY SSF52467 194 314 1.71E-46 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TL08_06680 1d57af5d61763629904f70a2c6d0e052 319 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 258 284 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 TL08_06680 1d57af5d61763629904f70a2c6d0e052 319 SMART SM00893 4 186 6.8E-23 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TL08_06680 1d57af5d61763629904f70a2c6d0e052 319 Gene3D G3DSA:3.40.50.1220 188 319 2.5E-55 T 12-10-2018 TL08_06680 1d57af5d61763629904f70a2c6d0e052 319 PIRSF PIRSF000089 1 319 4.5E-98 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 SUPERFAMILY SSF52540 10 217 5.68E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 SUPERFAMILY SSF50465 319 420 2.54E-23 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 SUPERFAMILY SSF50447 223 314 5.08E-18 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 PRINTS PR00315 GTP-binding elongation factor signature 106 117 9.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 PRINTS PR00315 GTP-binding elongation factor signature 90 100 9.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 PRINTS PR00315 GTP-binding elongation factor signature 11 24 9.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 PRINTS PR00315 GTP-binding elongation factor signature 70 78 9.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 PRINTS PR00315 GTP-binding elongation factor signature 143 152 9.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 Gene3D G3DSA:3.40.50.300 3 221 1.1E-64 T 12-10-2018 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 Gene3D G3DSA:2.40.30.10 316 420 1.1E-26 T 12-10-2018 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 10 420 8.8E-162 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 Pfam PF00009 Elongation factor Tu GTP binding domain 11 208 1.7E-37 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 Gene3D G3DSA:2.40.30.10 224 313 1.2E-21 T 12-10-2018 TL08_21435 91ecdfd55be0a8151071d94cfe96138e 454 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 63 78 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TL08_03900 79ffa7c6748ee1c0545c8887056e9e37 439 Gene3D G3DSA:3.40.190.10 34 432 7.2E-57 T 12-10-2018 TL08_03900 79ffa7c6748ee1c0545c8887056e9e37 439 Pfam PF13416 Bacterial extracellular solute-binding protein 57 349 4.1E-20 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_03900 79ffa7c6748ee1c0545c8887056e9e37 439 SUPERFAMILY SSF53850 36 432 7.24E-51 T 12-10-2018 TL08_03930 bc282ab53b0a8d9335b63de84ae5b670 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03930 bc282ab53b0a8d9335b63de84ae5b670 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03930 bc282ab53b0a8d9335b63de84ae5b670 306 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 206 4.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03930 bc282ab53b0a8d9335b63de84ae5b670 306 Pfam PF00106 short chain dehydrogenase 5 146 5.3E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03930 bc282ab53b0a8d9335b63de84ae5b670 306 SUPERFAMILY SSF51735 2 276 4.41E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_03930 bc282ab53b0a8d9335b63de84ae5b670 306 Gene3D G3DSA:3.40.50.720 1 305 1.4E-47 T 12-10-2018 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 ProSitePatterns PS00216 Sugar transport proteins signature 1. 282 298 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 Gene3D G3DSA:1.20.1250.20 24 255 1.5E-43 T 12-10-2018 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 PRINTS PR01035 Tetracycline resistance protein signature 35 51 1.4E-10 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 PRINTS PR01035 Tetracycline resistance protein signature 178 198 1.4E-10 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 PRINTS PR01035 Tetracycline resistance protein signature 150 172 1.4E-10 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 PRINTS PR01035 Tetracycline resistance protein signature 353 376 1.4E-10 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 PRINTS PR01035 Tetracycline resistance protein signature 264 284 1.4E-10 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 Gene3D G3DSA:1.20.1720.10 256 424 6.2E-25 T 12-10-2018 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 SUPERFAMILY SSF103473 10 414 4.71E-78 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 Pfam PF07690 Major Facilitator Superfamily 29 257 3.7E-33 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_05155 5692025c2cdc3042ea8259112c7b170e 451 Pfam PF00083 Sugar (and other) transporter 261 405 6.1E-10 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TL08_04280 e9d7af5220f2cdda6d90d2a404bbb8fe 228 Gene3D G3DSA:3.40.109.10 4 224 6.8E-59 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_04280 e9d7af5220f2cdda6d90d2a404bbb8fe 228 SUPERFAMILY SSF55469 12 227 1.44E-34 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_04280 e9d7af5220f2cdda6d90d2a404bbb8fe 228 Pfam PF00881 Nitroreductase family 16 203 9.3E-26 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TL08_26820 b2b7ea0bf745e0ed558f9ef69ee0de4e 559 PIRSF PIRSF010361 46 525 4.2E-165 T 12-10-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane TL08_26820 b2b7ea0bf745e0ed558f9ef69ee0de4e 559 Pfam PF09594 Glycosyltransferase family 87 199 416 4.0E-11 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 TL08_06285 c27b463839b43413d03134aa82318b41 203 SUPERFAMILY SSF46689 12 90 6.14E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06285 c27b463839b43413d03134aa82318b41 203 Gene3D G3DSA:1.10.357.10 61 201 4.6E-30 T 12-10-2018 TL08_06285 c27b463839b43413d03134aa82318b41 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 67 4.2E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06285 c27b463839b43413d03134aa82318b41 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.8E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06285 c27b463839b43413d03134aa82318b41 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.8E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06285 c27b463839b43413d03134aa82318b41 203 Gene3D G3DSA:1.10.10.60 10 59 2.1E-18 T 12-10-2018 TL08_03065 42087a6ebf69c1cb774761d54cc1792c 136 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 23 136 9.3E-48 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03065 42087a6ebf69c1cb774761d54cc1792c 136 SUPERFAMILY SSF53137 23 134 2.16E-46 T 12-10-2018 TL08_03065 42087a6ebf69c1cb774761d54cc1792c 136 Gene3D G3DSA:3.30.420.100 22 136 8.6E-40 T 12-10-2018 TL08_03065 42087a6ebf69c1cb774761d54cc1792c 136 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 25 136 8.6E-40 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03065 42087a6ebf69c1cb774761d54cc1792c 136 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 22 136 27.823 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_02025 f8242789ab74b1b7618aee2456dcecdb 340 SUPERFAMILY SSF53067 121 314 4.06E-33 T 12-10-2018 TL08_02025 f8242789ab74b1b7618aee2456dcecdb 340 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 9 314 1.1E-20 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 TL08_02025 f8242789ab74b1b7618aee2456dcecdb 340 Gene3D G3DSA:3.30.420.40 8 120 2.4E-54 T 12-10-2018 TL08_02025 f8242789ab74b1b7618aee2456dcecdb 340 Gene3D G3DSA:3.30.420.40 121 275 2.4E-54 T 12-10-2018 TL08_02025 f8242789ab74b1b7618aee2456dcecdb 340 SUPERFAMILY SSF53067 6 117 5.46E-14 T 12-10-2018 TL08_09085 9f75978737aac1af0c4f5cb567d57997 436 Gene3D G3DSA:3.40.640.10 98 328 1.4E-112 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_09085 9f75978737aac1af0c4f5cb567d57997 436 SUPERFAMILY SSF53383 77 422 3.09E-90 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_09085 9f75978737aac1af0c4f5cb567d57997 436 Pfam PF00155 Aminotransferase class I and II 81 421 1.3E-55 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_09085 9f75978737aac1af0c4f5cb567d57997 436 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 277 286 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TL08_09085 9f75978737aac1af0c4f5cb567d57997 436 Gene3D G3DSA:3.90.1150.10 84 414 1.4E-112 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_12085 1511d42af51a757c899dab8740f166b3 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 50.43 T 12-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 TL08_12085 1511d42af51a757c899dab8740f166b3 452 PIRSF PIRSF018077 1 452 4.7E-180 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 TL08_12085 1511d42af51a757c899dab8740f166b3 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 9.4E-235 T 12-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 TL08_12085 1511d42af51a757c899dab8740f166b3 452 Pfam PF03136 Pup-ligase protein 4 422 1.8E-155 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 TL08_17310 5a4b3889b61f0b54fbce7e9cd468dfd1 1222 SUPERFAMILY SSF52743 211 493 5.5E-83 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_17310 5a4b3889b61f0b54fbce7e9cd468dfd1 1222 PRINTS PR00723 Subtilisin serine protease family (S8) signature 230 249 1.5E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_17310 5a4b3889b61f0b54fbce7e9cd468dfd1 1222 PRINTS PR00723 Subtilisin serine protease family (S8) signature 267 280 1.5E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_17310 5a4b3889b61f0b54fbce7e9cd468dfd1 1222 PRINTS PR00723 Subtilisin serine protease family (S8) signature 434 450 1.5E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_17310 5a4b3889b61f0b54fbce7e9cd468dfd1 1222 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 435 445 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_17310 5a4b3889b61f0b54fbce7e9cd468dfd1 1222 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 271 281 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_17310 5a4b3889b61f0b54fbce7e9cd468dfd1 1222 Gene3D G3DSA:3.40.50.200 205 495 2.0E-90 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_17310 5a4b3889b61f0b54fbce7e9cd468dfd1 1222 Pfam PF00082 Subtilase family 230 484 5.6E-56 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_14095 165fd503acae08ea82cffb862b31d437 225 SUPERFAMILY SSF55729 21 184 7.22E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_14095 165fd503acae08ea82cffb862b31d437 225 Gene3D G3DSA:3.40.630.30 23 205 2.5E-22 T 12-10-2018 TL08_14095 165fd503acae08ea82cffb862b31d437 225 Pfam PF13302 Acetyltransferase (GNAT) domain 27 160 5.7E-13 T 12-10-2018 IPR000182 GNAT domain TL08_22120 ccfa5bee49342cde32bb2b7b3973c93e 430 Pfam PF09661 Protein of unknown function (DUF2398) 34 396 8.4E-89 T 12-10-2018 IPR013494 Conserved hypothetical protein CHP02678 TL08_22120 ccfa5bee49342cde32bb2b7b3973c93e 430 TIGRFAM TIGR02678 TIGR02678: TIGR02678 family protein 34 370 7.3E-37 T 12-10-2018 IPR013494 Conserved hypothetical protein CHP02678 TL08_03870 2c45b5b817a159e66881b284f44e952a 457 SUPERFAMILY SSF54631 319 455 8.09E-17 T 12-10-2018 TL08_03870 2c45b5b817a159e66881b284f44e952a 457 Pfam PF00571 CBS domain 327 391 2.6E-4 T 12-10-2018 IPR000644 CBS domain TL08_03870 2c45b5b817a159e66881b284f44e952a 457 Pfam PF00571 CBS domain 402 454 7.6E-6 T 12-10-2018 IPR000644 CBS domain TL08_03870 2c45b5b817a159e66881b284f44e952a 457 Gene3D G3DSA:3.40.50.1100 41 154 1.6E-116 T 12-10-2018 TL08_03870 2c45b5b817a159e66881b284f44e952a 457 Gene3D G3DSA:3.10.580.10 319 456 9.4E-18 T 12-10-2018 TL08_03870 2c45b5b817a159e66881b284f44e952a 457 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 TL08_03870 2c45b5b817a159e66881b284f44e952a 457 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 454 2.4E-196 T 12-10-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 TL08_03870 2c45b5b817a159e66881b284f44e952a 457 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 296 3.7E-65 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_03870 2c45b5b817a159e66881b284f44e952a 457 Gene3D G3DSA:3.40.50.1100 9 304 1.6E-116 T 12-10-2018 TL08_03870 2c45b5b817a159e66881b284f44e952a 457 SUPERFAMILY SSF53686 1 317 2.1E-94 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_03870 2c45b5b817a159e66881b284f44e952a 457 SMART SM00116 339 392 0.011 T 12-10-2018 IPR000644 CBS domain TL08_03870 2c45b5b817a159e66881b284f44e952a 457 SMART SM00116 409 454 0.0056 T 12-10-2018 IPR000644 CBS domain TL08_24345 4627af1f095b6086a57be6319de64d5d 234 SUPERFAMILY SSF88946 57 161 5.76E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_24345 4627af1f095b6086a57be6319de64d5d 234 Gene3D G3DSA:1.10.10.10 168 234 1.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_24345 4627af1f095b6086a57be6319de64d5d 234 SUPERFAMILY SSF88659 178 233 1.4E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_24345 4627af1f095b6086a57be6319de64d5d 234 Pfam PF08281 Sigma-70, region 4 180 226 2.4E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_24345 4627af1f095b6086a57be6319de64d5d 234 Pfam PF04542 Sigma-70 region 2 80 149 2.6E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_24345 4627af1f095b6086a57be6319de64d5d 234 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 76 233 1.9E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_24345 4627af1f095b6086a57be6319de64d5d 234 Gene3D G3DSA:1.10.1740.10 61 146 2.3E-24 T 12-10-2018 TL08_22155 8f34afb8ed55b9a340b12e09029529b2 930 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 159 323 1.8E-9 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TL08_22155 8f34afb8ed55b9a340b12e09029529b2 930 SUPERFAMILY SSF52518 502 735 3.24E-85 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_22155 8f34afb8ed55b9a340b12e09029529b2 930 Gene3D G3DSA:3.40.50.970 501 740 1.0E-100 T 12-10-2018 TL08_22155 8f34afb8ed55b9a340b12e09029529b2 930 SUPERFAMILY SSF52922 738 916 2.79E-46 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_22155 8f34afb8ed55b9a340b12e09029529b2 930 Gene3D G3DSA:3.40.50.920 743 923 3.8E-57 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_22155 8f34afb8ed55b9a340b12e09029529b2 930 Gene3D G3DSA:3.40.50.970 78 500 9.1E-132 T 12-10-2018 TL08_22155 8f34afb8ed55b9a340b12e09029529b2 930 PIRSF PIRSF000156 19 924 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TL08_22155 8f34afb8ed55b9a340b12e09029529b2 930 SUPERFAMILY SSF52518 79 495 2.41E-130 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_22155 8f34afb8ed55b9a340b12e09029529b2 930 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 29 920 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TL08_06085 7a3502cf355d5bdd462ee88417fa76dc 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 5.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06085 7a3502cf355d5bdd462ee88417fa76dc 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 5.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06085 7a3502cf355d5bdd462ee88417fa76dc 207 SUPERFAMILY SSF46689 15 87 3.85E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06085 7a3502cf355d5bdd462ee88417fa76dc 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 69 3.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06085 7a3502cf355d5bdd462ee88417fa76dc 207 Gene3D G3DSA:1.10.10.60 11 78 8.4E-25 T 12-10-2018 TL08_06085 7a3502cf355d5bdd462ee88417fa76dc 207 SUPERFAMILY SSF48498 90 205 1.37E-26 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_06085 7a3502cf355d5bdd462ee88417fa76dc 207 Gene3D G3DSA:1.10.357.10 79 206 1.9E-33 T 12-10-2018 TL08_22700 42f0b1db6618038c6768d41f6f578276 354 SUPERFAMILY SSF53659 2 329 9.79E-107 T 12-10-2018 TL08_22700 42f0b1db6618038c6768d41f6f578276 354 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 1 338 57.128 T 12-10-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 TL08_22700 42f0b1db6618038c6768d41f6f578276 354 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 317 4.7E-87 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TL08_22700 42f0b1db6618038c6768d41f6f578276 354 Gene3D G3DSA:3.40.718.10 1 338 1.9E-127 T 12-10-2018 TL08_22700 42f0b1db6618038c6768d41f6f578276 354 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 232 251 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TL08_22700 42f0b1db6618038c6768d41f6f578276 354 SMART SM01329 2 334 2.2E-159 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TL08_04390 baa06f3683bdb6d6d9350ceb81923124 290 Pfam PF12730 ABC-2 family transporter protein 85 199 2.6E-11 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TL08_26740 196d89955977f17a42ddfdb17adba534 473 SUPERFAMILY SSF53187 5 466 2.69E-44 T 12-10-2018 TL08_26740 196d89955977f17a42ddfdb17adba534 473 Pfam PF07687 Peptidase dimerisation domain 207 366 6.6E-11 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TL08_26740 196d89955977f17a42ddfdb17adba534 473 Pfam PF01546 Peptidase family M20/M25/M40 95 462 1.3E-20 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TL08_26740 196d89955977f17a42ddfdb17adba534 473 Gene3D G3DSA:3.30.70.360 209 381 2.7E-69 T 12-10-2018 TL08_26740 196d89955977f17a42ddfdb17adba534 473 Gene3D G3DSA:3.40.630.10 17 455 2.7E-69 T 12-10-2018 TL08_14925 97f5609afc86e0c525ddfc3e12fe8e02 297 Pfam PF01636 Phosphotransferase enzyme family 26 254 1.1E-28 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_14925 97f5609afc86e0c525ddfc3e12fe8e02 297 Gene3D G3DSA:3.30.200.20 9 94 4.6E-13 T 12-10-2018 TL08_14925 97f5609afc86e0c525ddfc3e12fe8e02 297 Gene3D G3DSA:3.90.1200.10 100 252 6.9E-19 T 12-10-2018 TL08_14925 97f5609afc86e0c525ddfc3e12fe8e02 297 SUPERFAMILY SSF56112 21 262 3.94E-38 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_17870 2c9024e0cd8f5eedc7a25a375067e561 458 Gene3D G3DSA:3.50.30.30 112 240 1.3E-90 T 12-10-2018 TL08_17870 2c9024e0cd8f5eedc7a25a375067e561 458 Gene3D G3DSA:3.40.630.10 73 444 1.3E-90 T 12-10-2018 TL08_17870 2c9024e0cd8f5eedc7a25a375067e561 458 SUPERFAMILY SSF52025 131 218 8.63E-7 T 12-10-2018 TL08_17870 2c9024e0cd8f5eedc7a25a375067e561 458 Pfam PF02225 PA domain 144 225 1.1E-7 T 12-10-2018 IPR003137 PA domain TL08_17870 2c9024e0cd8f5eedc7a25a375067e561 458 SUPERFAMILY SSF53187 51 456 3.71E-57 T 12-10-2018 TL08_17870 2c9024e0cd8f5eedc7a25a375067e561 458 Pfam PF04389 Peptidase family M28 250 441 1.8E-36 T 12-10-2018 IPR007484 Peptidase M28 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 80 96 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 44 600 54.336 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 43 600 2.1E-260 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 Pfam PF08502 LeuA allosteric (dimerisation) domain 472 598 2.5E-32 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 Gene3D G3DSA:3.20.20.70 50 426 3.1E-156 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 SUPERFAMILY SSF110921 500 598 3.92E-34 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 Gene3D G3DSA:3.30.160.270 427 598 5.1E-61 T 12-10-2018 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 SMART SM00917 472 599 1.8E-34 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 SUPERFAMILY SSF51569 62 370 6.96E-97 T 12-10-2018 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 Pfam PF00682 HMGL-like 73 353 2.5E-77 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 283 296 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_01115 ec3480064d35ae4bf13091e0f97c8f7f 600 SUPERFAMILY SSF89000 438 488 2.12E-14 T 12-10-2018 TL08_24990 319b376d23222fc73539ab61d108db6d 123 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 2 120 1.1E-43 T 12-10-2018 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable TL08_24990 319b376d23222fc73539ab61d108db6d 123 SUPERFAMILY SSF50475 2 121 6.25E-24 T 12-10-2018 TL08_24990 319b376d23222fc73539ab61d108db6d 123 Gene3D G3DSA:2.30.110.10 1 122 2.8E-42 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_24990 319b376d23222fc73539ab61d108db6d 123 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 2 82 9.0E-13 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_24695 c2039d1c6a3810fecc5fcde96c210748 315 Pfam PF00892 EamA-like transporter family 151 286 2.2E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_24695 c2039d1c6a3810fecc5fcde96c210748 315 Pfam PF00892 EamA-like transporter family 12 140 9.6E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_24695 c2039d1c6a3810fecc5fcde96c210748 315 SUPERFAMILY SSF103481 41 143 1.7E-10 T 12-10-2018 TL08_24695 c2039d1c6a3810fecc5fcde96c210748 315 SUPERFAMILY SSF103481 190 290 1.57E-10 T 12-10-2018 TL08_12420 3955984d1ba5b82252547d3418bb797d 188 SUPERFAMILY SSF48498 81 186 8.54E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_12420 3955984d1ba5b82252547d3418bb797d 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 3.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_12420 3955984d1ba5b82252547d3418bb797d 188 Gene3D G3DSA:1.10.357.10 2 188 1.3E-47 T 12-10-2018 TL08_12420 3955984d1ba5b82252547d3418bb797d 188 SUPERFAMILY SSF46689 4 81 1.65E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_05870 6852e95ae72938675bd1ddfc2f927c8d 266 SUPERFAMILY SSF53335 17 263 9.41E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_05870 6852e95ae72938675bd1ddfc2f927c8d 266 Pfam PF13489 Methyltransferase domain 52 161 2.0E-7 T 12-10-2018 TL08_05870 6852e95ae72938675bd1ddfc2f927c8d 266 Gene3D G3DSA:3.40.50.150 26 260 2.8E-60 T 12-10-2018 TL08_05870 6852e95ae72938675bd1ddfc2f927c8d 266 Gene3D G3DSA:2.20.25.570 160 221 2.8E-60 T 12-10-2018 TL08_15125 3655362964122c416ea9cf8a6157b56e 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 Pfam PF00106 short chain dehydrogenase 7 193 1.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 Gene3D G3DSA:3.40.50.720 3 277 9.0E-65 T 12-10-2018 TL08_15125 3655362964122c416ea9cf8a6157b56e 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 9.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 9.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_15125 3655362964122c416ea9cf8a6157b56e 282 SUPERFAMILY SSF51735 4 240 1.53E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_25405 219ff7531a39efeb28eebdbf6593cf6d 889 SMART SM00028 108 141 120.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_25405 219ff7531a39efeb28eebdbf6593cf6d 889 SMART SM00028 153 186 0.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_25405 219ff7531a39efeb28eebdbf6593cf6d 889 SMART SM00028 193 226 39.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_25405 219ff7531a39efeb28eebdbf6593cf6d 889 SMART SM00028 232 265 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_25405 219ff7531a39efeb28eebdbf6593cf6d 889 Pfam PF12770 CHAT domain 628 872 3.0E-31 T 12-10-2018 IPR024983 CHAT domain TL08_25405 219ff7531a39efeb28eebdbf6593cf6d 889 SUPERFAMILY SSF48452 112 294 9.3E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_25405 219ff7531a39efeb28eebdbf6593cf6d 889 Gene3D G3DSA:1.25.40.10 81 385 6.0E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10290 75b4eeadf571e6f617939ffe97347bc5 345 Pfam PF12679 ABC-2 family transporter protein 84 343 6.2E-16 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TL08_02480 47715a25cebf24634f63e1aa22802d35 160 Gene3D G3DSA:1.10.10.10 2 52 1.1E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_02480 47715a25cebf24634f63e1aa22802d35 160 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 1.3E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_02480 47715a25cebf24634f63e1aa22802d35 160 SUPERFAMILY SSF54909 61 143 3.75E-16 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_02480 47715a25cebf24634f63e1aa22802d35 160 SUPERFAMILY SSF46785 1 60 3.23E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_02480 47715a25cebf24634f63e1aa22802d35 160 Gene3D G3DSA:3.30.70.920 54 135 2.4E-22 T 12-10-2018 TL08_02480 47715a25cebf24634f63e1aa22802d35 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.8E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_02480 47715a25cebf24634f63e1aa22802d35 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.8E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_02480 47715a25cebf24634f63e1aa22802d35 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.8E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_02480 47715a25cebf24634f63e1aa22802d35 160 SMART SM00344 1 108 1.8E-37 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TL08_02480 47715a25cebf24634f63e1aa22802d35 160 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TL08_02480 47715a25cebf24634f63e1aa22802d35 160 Pfam PF01037 Lrp/AsnC ligand binding domain 76 138 1.0E-16 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TL08_12250 4a4d329be82232583ad5b0b94d21428c 297 SMART SM00530 9 81 6.2E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_12250 4a4d329be82232583ad5b0b94d21428c 297 SUPERFAMILY SSF47413 8 78 2.7E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_12250 4a4d329be82232583ad5b0b94d21428c 297 Pfam PF13560 Helix-turn-helix domain 6 84 1.2E-19 T 12-10-2018 TL08_12250 4a4d329be82232583ad5b0b94d21428c 297 Gene3D G3DSA:1.10.260.40 4 83 5.1E-9 T 12-10-2018 TL08_12250 4a4d329be82232583ad5b0b94d21428c 297 Gene3D G3DSA:3.30.450.180 104 261 7.3E-15 T 12-10-2018 TL08_01295 a7722983db20d4969013ff7ea883d647 268 Gene3D G3DSA:1.10.340.30 13 124 3.2E-69 T 12-10-2018 TL08_01295 a7722983db20d4969013ff7ea883d647 268 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 27 160 2.3E-18 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TL08_01295 a7722983db20d4969013ff7ea883d647 268 Gene3D G3DSA:1.10.1670.10 8 195 3.2E-69 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TL08_01295 a7722983db20d4969013ff7ea883d647 268 Pfam PF00633 Helix-hairpin-helix motif 92 118 6.0E-9 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 TL08_01295 a7722983db20d4969013ff7ea883d647 268 SMART SM00478 30 177 4.6E-54 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TL08_01295 a7722983db20d4969013ff7ea883d647 268 SUPERFAMILY SSF48150 3 202 1.88E-62 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TL08_01295 a7722983db20d4969013ff7ea883d647 268 Hamap MF_00942 Endonuclease III [nth]. 1 201 34.138 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TL08_01295 a7722983db20d4969013ff7ea883d647 268 TIGRFAM TIGR01083 nth: endonuclease III 4 186 1.1E-72 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TL08_01295 a7722983db20d4969013ff7ea883d647 268 ProSitePatterns PS01155 Endonuclease III family signature. 94 123 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 TL08_01295 a7722983db20d4969013ff7ea883d647 268 SMART SM00525 178 198 4.4E-4 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TL08_01295 a7722983db20d4969013ff7ea883d647 268 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 179 195 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TL08_23895 4a63dd412226c150556caf3944198d6d 355 Gene3D G3DSA:3.40.50.2300 58 336 2.0E-72 T 12-10-2018 TL08_23895 4a63dd412226c150556caf3944198d6d 355 Gene3D G3DSA:3.40.50.2300 160 348 2.0E-72 T 12-10-2018 TL08_23895 4a63dd412226c150556caf3944198d6d 355 SUPERFAMILY SSF53822 55 348 3.93E-55 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_23895 4a63dd412226c150556caf3944198d6d 355 Pfam PF13407 Periplasmic binding protein domain 58 315 5.5E-43 T 12-10-2018 IPR025997 Periplasmic binding protein TL08_00880 8d2989951ff6be14208362277ed0b9cc 287 SUPERFAMILY SSF48498 95 237 1.33E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_00880 8d2989951ff6be14208362277ed0b9cc 287 Gene3D G3DSA:1.10.10.60 12 82 8.3E-25 T 12-10-2018 TL08_00880 8d2989951ff6be14208362277ed0b9cc 287 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 77 4.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_00880 8d2989951ff6be14208362277ed0b9cc 287 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 95 232 1.3E-19 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 TL08_00880 8d2989951ff6be14208362277ed0b9cc 287 Gene3D G3DSA:1.10.357.10 87 252 5.9E-33 T 12-10-2018 TL08_00880 8d2989951ff6be14208362277ed0b9cc 287 SUPERFAMILY SSF46689 22 84 4.39E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_10110 e00959e729fe51a2e67629323c5b2f20 142 Pfam PF00293 NUDIX domain 5 119 5.7E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_10110 e00959e729fe51a2e67629323c5b2f20 142 Gene3D G3DSA:3.90.79.10 1 141 1.0E-28 T 12-10-2018 TL08_10110 e00959e729fe51a2e67629323c5b2f20 142 SUPERFAMILY SSF55811 2 137 5.28E-27 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_12265 f18fc68e2135256851a39d8dea1bce19 65 Pfam PF04149 Domain of unknown function (DUF397) 15 58 1.7E-6 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_25640 13575fddf341fe4ce2c960aed17fd362 333 Pfam PF00535 Glycosyl transferase family 2 12 139 1.3E-19 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_25640 13575fddf341fe4ce2c960aed17fd362 333 Gene3D G3DSA:3.90.550.10 4 237 1.0E-37 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_25640 13575fddf341fe4ce2c960aed17fd362 333 SUPERFAMILY SSF53448 9 237 5.07E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_05750 28f931c6706f3856af44142b75839f18 392 Pfam PF12698 ABC-2 family transporter protein 24 384 1.2E-31 T 12-10-2018 TL08_08835 321bfac9fe713d8cb5c7f2751827bebc 331 ProSitePatterns PS01125 ROK family signature. 151 178 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_08835 321bfac9fe713d8cb5c7f2751827bebc 331 Gene3D G3DSA:3.30.420.40 18 320 2.4E-93 T 12-10-2018 TL08_08835 321bfac9fe713d8cb5c7f2751827bebc 331 SUPERFAMILY SSF53067 17 326 1.12E-60 T 12-10-2018 TL08_08835 321bfac9fe713d8cb5c7f2751827bebc 331 Gene3D G3DSA:3.30.420.40 143 307 2.4E-93 T 12-10-2018 TL08_08835 321bfac9fe713d8cb5c7f2751827bebc 331 Pfam PF00480 ROK family 18 323 8.8E-67 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_03975 cba79d0e4ca8920629c7aca798391075 63 Pfam PF04149 Domain of unknown function (DUF397) 7 58 4.0E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 Gene3D G3DSA:3.40.1110.10 495 618 9.9E-85 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00943 Copper-transporting ATPase signature 720 734 1.3E-6 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00943 Copper-transporting ATPase signature 663 680 1.3E-6 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00943 Copper-transporting ATPase signature 407 421 1.3E-6 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00943 Copper-transporting ATPase signature 64 78 1.3E-6 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00943 Copper-transporting ATPase signature 254 273 1.3E-6 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00943 Copper-transporting ATPase signature 467 482 1.3E-6 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 Gene3D G3DSA:3.30.70.100 48 114 5.3E-20 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 Gene3D G3DSA:3.40.50.1000 465 738 9.9E-85 T 12-10-2018 IPR023214 HAD superfamily TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 Pfam PF00403 Heavy-metal-associated domain 53 110 2.9E-13 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 Pfam PF00702 haloacid dehalogenase-like hydrolase 480 700 1.1E-43 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 ProSitePatterns PS01047 Heavy-metal-associated domain. 54 82 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 2.0E-25 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 484 498 2.0E-25 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 686 705 2.0E-25 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 643 2.0E-25 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 709 721 2.0E-25 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 611 622 2.0E-25 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 258 768 2.2E-82 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 SUPERFAMILY SSF81665 260 758 1.7E-9 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 SUPERFAMILY SSF55008 48 115 6.81E-19 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 249 789 3.4E-149 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 SUPERFAMILY SSF56784 482 786 2.03E-55 T 12-10-2018 IPR036412 HAD-like superfamily TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 SUPERFAMILY SSF81653 290 384 7.19E-24 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 203 788 3.3E-172 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 Pfam PF00122 E1-E2 ATPase 287 462 7.3E-49 T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 ProSitePatterns PS01229 Hypothetical cof family signature 2. 686 708 - T 12-10-2018 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 486 492 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TL08_07550 67d480c77a582dd38ec7faabadd09fde 804 Gene3D G3DSA:2.70.150.20 278 389 3.0E-34 T 12-10-2018 TL08_07055 ba4458ae062e226153721040149d1ead 183 Pfam PF04978 Protein of unknown function (DUF664) 22 178 1.2E-46 T 12-10-2018 IPR007061 Protein of unknown function DUF664 TL08_07055 ba4458ae062e226153721040149d1ead 183 SUPERFAMILY SSF109854 6 177 5.34E-38 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_07055 ba4458ae062e226153721040149d1ead 183 Gene3D G3DSA:1.20.120.450 3 180 1.0E-39 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_08215 96edba5e80c7f56924c372be59cef050 397 SUPERFAMILY SSF48264 17 397 4.85E-80 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 Gene3D G3DSA:1.10.630.10 11 397 6.0E-105 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 Pfam PF00067 Cytochrome P450 270 364 4.8E-14 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 PRINTS PR00359 B-class P450 signature 337 346 3.3E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 PRINTS PR00359 B-class P450 signature 288 315 3.3E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 PRINTS PR00359 B-class P450 signature 316 331 3.3E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 PRINTS PR00359 B-class P450 signature 151 166 3.3E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 PRINTS PR00359 B-class P450 signature 189 211 3.3E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 PRINTS PR00359 B-class P450 signature 87 98 3.3E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 PRINTS PR00359 B-class P450 signature 134 150 3.3E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 PRINTS PR00359 B-class P450 signature 269 280 3.3E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 PRINTS PR00359 B-class P450 signature 346 357 3.3E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08215 96edba5e80c7f56924c372be59cef050 397 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Gene3D G3DSA:1.10.150.20 691 750 1.2E-20 T 12-10-2018 TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Gene3D G3DSA:3.30.420.340 463 549 1.9E-22 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Pfam PF02151 UvrB/uvrC motif 225 258 4.0E-10 T 12-10-2018 IPR001943 UVR domain GO:0005515 TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Pfam PF01541 GIY-YIG catalytic domain 34 108 1.9E-9 T 12-10-2018 IPR000305 GIY-YIG endonuclease TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Gene3D G3DSA:3.30.420.340 600 690 1.0E-20 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 SMART SM00465 33 115 3.8E-19 T 12-10-2018 IPR000305 GIY-YIG endonuclease TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 SUPERFAMILY SSF82771 33 117 1.57E-21 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 SUPERFAMILY SSF46600 210 263 3.4E-14 T 12-10-2018 IPR036876 UVR domain superfamily TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Hamap MF_00203 UvrABC system protein C [uvrC]. 20 748 29.64 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Pfam PF14520 Helix-hairpin-helix domain 699 749 1.8E-8 T 12-10-2018 TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 468 683 6.6E-46 T 12-10-2018 IPR001162 UvrC family homology region TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 SUPERFAMILY SSF47781 644 751 2.89E-25 T 12-10-2018 IPR010994 RuvA domain 2-like TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Gene3D G3DSA:3.40.1440.10 23 119 1.1E-28 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 SMART SM00278 697 716 20.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 SMART SM00278 729 748 3.4 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TL08_11605 198c41ef54917c5e13761b8e8de6e692 765 Gene3D G3DSA:4.10.860.10 222 261 4.5E-6 T 12-10-2018 TL08_19500 97a6efd7d228d041375b1cd378443028 281 Gene3D G3DSA:3.40.50.720 99 229 7.1E-57 T 12-10-2018 TL08_19500 97a6efd7d228d041375b1cd378443028 281 SMART SM00829 7 278 3.2E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_19500 97a6efd7d228d041375b1cd378443028 281 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1 60 6.6E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_19500 97a6efd7d228d041375b1cd378443028 281 SUPERFAMILY SSF51735 89 213 2.03E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19500 97a6efd7d228d041375b1cd378443028 281 Gene3D G3DSA:3.90.180.10 1 277 7.1E-57 T 12-10-2018 TL08_19500 97a6efd7d228d041375b1cd378443028 281 SUPERFAMILY SSF50129 1 128 7.39E-24 T 12-10-2018 IPR011032 GroES-like superfamily TL08_19500 97a6efd7d228d041375b1cd378443028 281 Pfam PF13602 Zinc-binding dehydrogenase 158 278 7.5E-13 T 12-10-2018 TL08_08790 1e055cb2cdb0cd487ba36dada4de1a1b 253 Gene3D G3DSA:3.30.420.10 13 234 2.2E-62 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_08790 1e055cb2cdb0cd487ba36dada4de1a1b 253 SUPERFAMILY SSF53098 27 220 4.1E-56 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_08790 1e055cb2cdb0cd487ba36dada4de1a1b 253 Hamap MF_00052_B Ribonuclease HII [rnhB]. 32 215 32.947 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 TL08_08790 1e055cb2cdb0cd487ba36dada4de1a1b 253 Pfam PF01351 Ribonuclease HII 34 215 4.9E-35 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain TL08_25910 de53d731f9a4be2a728ff1a43d7b1a6f 272 Gene3D G3DSA:1.10.10.10 117 224 1.7E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25910 de53d731f9a4be2a728ff1a43d7b1a6f 272 SUPERFAMILY SSF46894 121 221 2.01E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_25910 de53d731f9a4be2a728ff1a43d7b1a6f 272 SMART SM00862 146 220 2.1E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_25910 de53d731f9a4be2a728ff1a43d7b1a6f 272 Gene3D G3DSA:3.40.50.2300 3 116 5.7E-38 T 12-10-2018 TL08_25910 de53d731f9a4be2a728ff1a43d7b1a6f 272 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 1.0E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_21635 68b181baa5f88b5666ad4b0da7652766 188 Pfam PF05076 Suppressor of fused protein (SUFU) 68 184 1.2E-6 T 12-10-2018 IPR020941 Suppressor of fused-like domain Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5610787|Reactome: R-HSA-5632684 TL08_12615 42e749bd77bd27aaa8d79ff2d465ffb4 453 Pfam PF13556 PucR C-terminal helix-turn-helix domain 390 447 1.0E-17 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain TL08_12615 42e749bd77bd27aaa8d79ff2d465ffb4 453 Gene3D G3DSA:1.10.10.2840 325 452 6.7E-22 T 12-10-2018 TL08_09360 967e9840cad795dc9d037a54e97e55c6 147 Pfam PF00583 Acetyltransferase (GNAT) family 23 98 5.1E-14 T 12-10-2018 IPR000182 GNAT domain TL08_09360 967e9840cad795dc9d037a54e97e55c6 147 SUPERFAMILY SSF55729 20 105 2.92E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_09360 967e9840cad795dc9d037a54e97e55c6 147 Gene3D G3DSA:3.40.630.30 2 122 3.2E-25 T 12-10-2018 TL08_20655 6de0050b5addb0e4ed045a173f0dce8d 432 Gene3D G3DSA:3.40.190.10 151 424 3.3E-120 T 12-10-2018 TL08_20655 6de0050b5addb0e4ed045a173f0dce8d 432 SUPERFAMILY SSF53850 38 431 9.39E-59 T 12-10-2018 TL08_20655 6de0050b5addb0e4ed045a173f0dce8d 432 Pfam PF01547 Bacterial extracellular solute-binding protein 55 340 6.7E-26 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_20655 6de0050b5addb0e4ed045a173f0dce8d 432 Gene3D G3DSA:3.40.190.10 41 379 3.3E-120 T 12-10-2018 TL08_09660 207a9addf3d8359476d711988010083f 536 PIRSF PIRSF002741 7 528 1.2E-81 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_09660 207a9addf3d8359476d711988010083f 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 442 2.9E-68 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_09660 207a9addf3d8359476d711988010083f 536 Gene3D G3DSA:3.10.105.10 279 497 1.7E-106 T 12-10-2018 TL08_09660 207a9addf3d8359476d711988010083f 536 Gene3D G3DSA:3.40.190.10 63 511 1.7E-106 T 12-10-2018 TL08_09660 207a9addf3d8359476d711988010083f 536 SUPERFAMILY SSF53850 39 527 8.69E-97 T 12-10-2018 TL08_09660 207a9addf3d8359476d711988010083f 536 Gene3D G3DSA:3.90.76.10 65 181 1.7E-106 T 12-10-2018 TL08_09210 319def9f7cb8445f8aaf70befb84ceb7 443 Pfam PF01554 MatE 244 395 1.4E-10 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TL08_09210 319def9f7cb8445f8aaf70befb84ceb7 443 Pfam PF01554 MatE 26 186 3.3E-27 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TL08_09210 319def9f7cb8445f8aaf70befb84ceb7 443 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 413 6.2E-91 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TL08_09210 319def9f7cb8445f8aaf70befb84ceb7 443 PIRSF PIRSF006603 7 443 4.9E-50 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TL08_25755 5c12205d212d96a5b79f7a68e1290791 411 SUPERFAMILY SSF53383 19 407 1.73E-75 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_25755 5c12205d212d96a5b79f7a68e1290791 411 Hamap MF_01970 Kynureninase [kynU]. 7 406 32.209 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 TL08_25755 5c12205d212d96a5b79f7a68e1290791 411 TIGRFAM TIGR01814 kynureninase: kynureninase 20 405 4.7E-77 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 TL08_25755 5c12205d212d96a5b79f7a68e1290791 411 PIRSF PIRSF038800 12 411 3.2E-124 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 TL08_25755 5c12205d212d96a5b79f7a68e1290791 411 Gene3D G3DSA:3.90.1150.10 23 405 4.9E-136 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_25755 5c12205d212d96a5b79f7a68e1290791 411 Pfam PF00266 Aminotransferase class-V 168 368 2.2E-19 T 12-10-2018 IPR000192 Aminotransferase class V domain TL08_25755 5c12205d212d96a5b79f7a68e1290791 411 Gene3D G3DSA:3.40.640.10 53 311 4.9E-136 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_26470 36d09d37dd14c4ee46815ea21659ffcf 369 SUPERFAMILY SSF51735 140 281 3.51E-19 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_26470 36d09d37dd14c4ee46815ea21659ffcf 369 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 10 130 2.4E-19 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TL08_26470 36d09d37dd14c4ee46815ea21659ffcf 369 Gene3D G3DSA:3.40.50.720 133 310 1.7E-72 T 12-10-2018 TL08_26470 36d09d37dd14c4ee46815ea21659ffcf 369 Gene3D G3DSA:3.40.50.720 9 335 1.7E-72 T 12-10-2018 TL08_26470 36d09d37dd14c4ee46815ea21659ffcf 369 SMART SM01003 10 140 5.2E-23 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TL08_26470 36d09d37dd14c4ee46815ea21659ffcf 369 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 145 355 3.0E-35 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TL08_26470 36d09d37dd14c4ee46815ea21659ffcf 369 SMART SM01002 152 302 2.1E-10 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TL08_26470 36d09d37dd14c4ee46815ea21659ffcf 369 SUPERFAMILY SSF52283 8 340 1.62E-29 T 12-10-2018 TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 SMART SM00847 460 555 5.8E-38 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 Gene3D G3DSA:3.40.50.300 30 250 5.8E-77 T 12-10-2018 TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 SMART SM00382 90 380 7.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 Pfam PF11898 Domain of unknown function (DUF3418) 708 1292 4.1E-229 T 12-10-2018 IPR024590 RNA helicase HrpA, C-terminal TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 618 694 3.9E-18 T 12-10-2018 IPR011709 Domain of unknown function DUF1605 TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 SMART SM00490 300 400 1.3E-12 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 SMART SM00487 71 257 1.8E-25 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 Pfam PF04408 Helicase associated domain (HA2) 462 552 5.0E-18 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 10 1291 0.0 T 12-10-2018 IPR010222 RNA helicase HrpA GO:0004004 TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 Gene3D G3DSA:3.40.50.300 251 416 5.3E-56 T 12-10-2018 TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 Gene3D G3DSA:1.20.120.1080 445 550 6.5E-20 T 12-10-2018 TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 Pfam PF00271 Helicase conserved C-terminal domain 282 399 4.5E-10 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_11265 012f970fa1edfcc2d2779969003ee430 1295 SUPERFAMILY SSF52540 72 597 2.87E-111 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05450 33ad10ed541c710a43d896153d424eea 171 Pfam PF02575 YbaB/EbfC DNA-binding family 31 114 7.5E-14 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_05450 33ad10ed541c710a43d896153d424eea 171 SUPERFAMILY SSF82607 34 118 2.09E-9 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_05450 33ad10ed541c710a43d896153d424eea 171 Gene3D G3DSA:3.30.1310.10 22 122 8.6E-14 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_22510 84b30bb26231dc35fd884949ceca006b 176 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 35 170 5.4E-14 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 TL08_26120 3a250982d6a93549aed436bcf7f3deb9 172 SUPERFAMILY SSF88659 81 163 4.11E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_26120 3a250982d6a93549aed436bcf7f3deb9 172 Gene3D G3DSA:1.10.1740.10 1 79 8.5E-10 T 12-10-2018 TL08_26120 3a250982d6a93549aed436bcf7f3deb9 172 SUPERFAMILY SSF88946 6 93 1.88E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_26120 3a250982d6a93549aed436bcf7f3deb9 172 Pfam PF08281 Sigma-70, region 4 106 157 1.4E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_26120 3a250982d6a93549aed436bcf7f3deb9 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 160 9.9E-24 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_26120 3a250982d6a93549aed436bcf7f3deb9 172 Gene3D G3DSA:1.10.10.10 80 164 1.3E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26120 3a250982d6a93549aed436bcf7f3deb9 172 Pfam PF04542 Sigma-70 region 2 17 79 1.6E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_26120 3a250982d6a93549aed436bcf7f3deb9 172 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 161 1.5E-47 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 TL08_00550 fe42075097a4358ca90f4e33733c33ea 401 Gene3D G3DSA:2.30.30.230 1 96 3.1E-9 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 TL08_00550 fe42075097a4358ca90f4e33733c33ea 401 SUPERFAMILY SSF56529 111 398 2.22E-86 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TL08_00550 fe42075097a4358ca90f4e33733c33ea 401 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 114 395 3.2E-53 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TL08_00550 fe42075097a4358ca90f4e33733c33ea 401 SUPERFAMILY SSF63433 2 108 1.02E-13 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 TL08_00550 fe42075097a4358ca90f4e33733c33ea 401 Gene3D G3DSA:3.90.850.10 106 400 9.7E-100 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 Hamap MF_00235 Adenylate kinase [adk]. 1 181 41.529 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 Pfam PF00406 Adenylate kinase 5 159 5.9E-51 T 12-10-2018 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 PRINTS PR00094 Adenylate kinase signature 4 17 5.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 PRINTS PR00094 Adenylate kinase signature 32 46 5.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 PRINTS PR00094 Adenylate kinase signature 147 161 5.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 PRINTS PR00094 Adenylate kinase signature 81 97 5.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 PRINTS PR00094 Adenylate kinase signature 130 145 5.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 Gene3D G3DSA:3.40.50.300 1 181 3.9E-61 T 12-10-2018 TL08_03095 a3acd632796ce88e3eafebcd68039d55 186 SUPERFAMILY SSF52540 2 177 1.34E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10040 fb5b15fe58b59f6cd7d35b22978dc6aa 148 SUPERFAMILY SSF55961 6 144 6.07E-32 T 12-10-2018 TL08_10040 fb5b15fe58b59f6cd7d35b22978dc6aa 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 143 2.9E-21 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TL08_10040 fb5b15fe58b59f6cd7d35b22978dc6aa 148 Gene3D G3DSA:3.30.530.20 3 148 1.9E-34 T 12-10-2018 IPR023393 START-like domain superfamily TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 182 2.0E-4 T 12-10-2018 TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.1E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 Pfam PF00106 short chain dehydrogenase 10 199 4.0E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 Gene3D G3DSA:3.40.50.720 7 244 4.7E-64 T 12-10-2018 TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05275 124532cfc660ae19eb671dd7f9a6f1c9 246 SUPERFAMILY SSF51735 7 234 6.39E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 SUPERFAMILY SSF82866 566 750 8.37E-29 T 12-10-2018 TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 7 454 33.449 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Pfam PF07549 SecD/SecF GG Motif 497 519 8.1E-7 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Pfam PF07549 SecD/SecF GG Motif 28 48 0.0034 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 208 434 1.1E-55 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 35 440 9.7E-105 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 PRINTS PR01755 Bacterial translocase SecF protein signature 657 675 1.5E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 PRINTS PR01755 Bacterial translocase SecF protein signature 609 623 1.5E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 PRINTS PR01755 Bacterial translocase SecF protein signature 689 704 1.5E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 PRINTS PR01755 Bacterial translocase SecF protein signature 500 515 1.5E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Gene3D G3DSA:1.20.1640.10 269 454 9.5E-8 T 12-10-2018 TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Gene3D G3DSA:1.20.1640.10 563 762 6.1E-9 T 12-10-2018 TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Gene3D G3DSA:3.30.70.3400 58 268 1.4E-47 T 12-10-2018 TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 475 752 23.644 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Pfam PF02355 Protein export membrane protein 573 748 1.7E-50 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Pfam PF02355 Protein export membrane protein 268 437 4.1E-8 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 Gene3D G3DSA:3.30.1360.200 113 265 1.4E-47 T 12-10-2018 TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 501 741 2.0E-54 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TL08_11935 3aaadc5fcce640a6d341a0b615314e88 773 SUPERFAMILY SSF82866 244 446 4.45E-31 T 12-10-2018 TL08_03720 4af41fac1d84fc544cc9a75f81a6bb94 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 6.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_03720 4af41fac1d84fc544cc9a75f81a6bb94 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 6.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_03720 4af41fac1d84fc544cc9a75f81a6bb94 199 Gene3D G3DSA:1.10.357.10 1 189 8.6E-48 T 12-10-2018 TL08_03720 4af41fac1d84fc544cc9a75f81a6bb94 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 52 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_03720 4af41fac1d84fc544cc9a75f81a6bb94 199 SUPERFAMILY SSF46689 3 76 6.16E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_03720 4af41fac1d84fc544cc9a75f81a6bb94 199 SUPERFAMILY SSF48498 77 187 2.52E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_03720 4af41fac1d84fc544cc9a75f81a6bb94 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 4.8E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_01875 10e651250df89b8b099cebe3413a99a7 477 PIRSF PIRSF016636 1 477 1.2E-147 T 12-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB TL08_01875 10e651250df89b8b099cebe3413a99a7 477 PIRSF PIRSF500217 1 477 7.4E-150 T 12-10-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 TL08_01875 10e651250df89b8b099cebe3413a99a7 477 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 151 349 6.4E-34 T 12-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT TL08_23550 db434f7e7c7144b7c76499f8e7bdd55f 251 Pfam PF00483 Nucleotidyl transferase 4 229 2.2E-26 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TL08_23550 db434f7e7c7144b7c76499f8e7bdd55f 251 Gene3D G3DSA:3.90.550.10 1 235 1.2E-60 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_23550 db434f7e7c7144b7c76499f8e7bdd55f 251 SUPERFAMILY SSF53448 2 229 1.98E-58 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_20950 40877776b7fe992d41cb2ab9f942c830 1590 Gene3D G3DSA:3.40.50.300 1141 1335 3.1E-24 T 12-10-2018 TL08_20950 40877776b7fe992d41cb2ab9f942c830 1590 Pfam PF13087 AAA domain 1122 1305 7.7E-14 T 12-10-2018 TL08_20950 40877776b7fe992d41cb2ab9f942c830 1590 Gene3D G3DSA:3.40.50.300 872 1108 9.5E-9 T 12-10-2018 TL08_20950 40877776b7fe992d41cb2ab9f942c830 1590 Gene3D G3DSA:3.40.50.300 303 518 7.6E-20 T 12-10-2018 TL08_20950 40877776b7fe992d41cb2ab9f942c830 1590 SUPERFAMILY SSF52540 358 1305 2.11E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20950 40877776b7fe992d41cb2ab9f942c830 1590 Gene3D G3DSA:3.40.960.10 1344 1451 1.1E-13 T 12-10-2018 TL08_20950 40877776b7fe992d41cb2ab9f942c830 1590 Pfam PF13086 AAA domain 361 424 6.6E-9 T 12-10-2018 TL08_20950 40877776b7fe992d41cb2ab9f942c830 1590 SUPERFAMILY SSF52980 1346 1451 9.65E-7 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TL08_09785 f2300115d419f1ec0b8a5dafcd78c3f8 423 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 78 402 3.5E-51 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_09785 f2300115d419f1ec0b8a5dafcd78c3f8 423 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 31 412 1.9E-184 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TL08_09785 f2300115d419f1ec0b8a5dafcd78c3f8 423 Gene3D G3DSA:3.40.50.1100 34 230 1.1E-185 T 12-10-2018 TL08_09785 f2300115d419f1ec0b8a5dafcd78c3f8 423 Gene3D G3DSA:3.40.50.1100 78 408 1.1E-185 T 12-10-2018 TL08_09785 f2300115d419f1ec0b8a5dafcd78c3f8 423 SUPERFAMILY SSF53686 27 414 7.46E-147 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_09785 f2300115d419f1ec0b8a5dafcd78c3f8 423 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 105 119 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TL08_09785 f2300115d419f1ec0b8a5dafcd78c3f8 423 PIRSF PIRSF001413 23 420 5.1E-158 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TL08_09785 f2300115d419f1ec0b8a5dafcd78c3f8 423 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 26 415 52.832 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TL08_05465 ea43c1f237f2fcbf1e7ec5a1ac26f8bf 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TL08_05465 ea43c1f237f2fcbf1e7ec5a1ac26f8bf 477 Gene3D G3DSA:3.40.605.10 28 462 2.6E-110 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_05465 ea43c1f237f2fcbf1e7ec5a1ac26f8bf 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TL08_05465 ea43c1f237f2fcbf1e7ec5a1ac26f8bf 477 Pfam PF00171 Aldehyde dehydrogenase family 29 466 5.1E-101 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_05465 ea43c1f237f2fcbf1e7ec5a1ac26f8bf 477 SUPERFAMILY SSF53720 12 471 6.68E-106 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_05465 ea43c1f237f2fcbf1e7ec5a1ac26f8bf 477 Gene3D G3DSA:3.40.309.10 256 443 2.6E-110 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_08140 33c220d3999c5dd97a62f53056495164 190 PIRSF PIRSF018427 1 189 7.2E-46 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 TL08_08140 33c220d3999c5dd97a62f53056495164 190 Gene3D G3DSA:3.90.79.10 2 187 2.9E-46 T 12-10-2018 TL08_08140 33c220d3999c5dd97a62f53056495164 190 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 19 176 7.8E-34 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 TL08_08140 33c220d3999c5dd97a62f53056495164 190 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 15 190 28.32 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 TL08_08140 33c220d3999c5dd97a62f53056495164 190 SUPERFAMILY SSF55811 17 180 5.01E-40 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_08140 33c220d3999c5dd97a62f53056495164 190 Pfam PF00293 NUDIX domain 42 175 4.3E-22 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.4E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.4E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.4E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 3.7E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 Pfam PF01016 Ribosomal L27 protein 2 80 6.1E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 SUPERFAMILY SSF110324 2 81 3.49E-32 T 12-10-2018 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 28.038 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 Gene3D G3DSA:2.40.50.100 21 85 5.4E-28 T 12-10-2018 TL08_08185 521cee7675f434ec75f34b8dcc69352c 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 6.0E-16 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26990 ff46dcdb54ff602732f6a07d32af5beb 91 SUPERFAMILY SSF52833 8 78 3.12E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_26990 ff46dcdb54ff602732f6a07d32af5beb 91 Pfam PF00462 Glutaredoxin 8 66 8.0E-14 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TL08_26990 ff46dcdb54ff602732f6a07d32af5beb 91 Gene3D G3DSA:3.40.30.10 4 86 4.1E-18 T 12-10-2018 TL08_10710 e18408f15a9f4035c07f79f80ca80975 159 SUPERFAMILY SSF47413 52 92 6.88E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_10710 e18408f15a9f4035c07f79f80ca80975 159 Gene3D G3DSA:1.10.260.40 12 145 3.6E-47 T 12-10-2018 TL08_02855 4c206687d6edfcf0e921942900c5fa88 168 PIRSF PIRSF018072 1 149 7.1E-53 T 12-10-2018 IPR016709 Uncharacterised protein family UPF0336 TL08_02855 4c206687d6edfcf0e921942900c5fa88 168 Hamap MF_00799 UPF0336 protein . 1 148 31.158 T 12-10-2018 IPR016709 Uncharacterised protein family UPF0336 TL08_02855 4c206687d6edfcf0e921942900c5fa88 168 Pfam PF13452 N-terminal half of MaoC dehydratase 7 135 1.3E-31 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 TL08_02855 4c206687d6edfcf0e921942900c5fa88 168 SUPERFAMILY SSF54637 8 148 3.2E-38 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_02855 4c206687d6edfcf0e921942900c5fa88 168 Gene3D G3DSA:3.10.129.10 1 151 7.1E-47 T 12-10-2018 TL08_25930 63f2b340587b1e0601c124c9db90f11b 146 Pfam PF14340 Domain of unknown function (DUF4395) 7 136 4.0E-40 T 12-10-2018 IPR025508 Domain of unknown function DUF4395 TL08_25930 63f2b340587b1e0601c124c9db90f11b 146 PIRSF PIRSF030042 5 144 1.2E-9 T 12-10-2018 IPR016942 Uncharacterised conserved protein UCP030042 TL08_02315 9a099d1a67cbc2519ba10970ac3d80c2 321 SUPERFAMILY SSF51730 50 316 2.08E-69 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like TL08_02315 9a099d1a67cbc2519ba10970ac3d80c2 321 Gene3D G3DSA:3.20.20.530 32 319 3.3E-91 T 12-10-2018 TL08_02315 9a099d1a67cbc2519ba10970ac3d80c2 321 PIRSF PIRSF000196 14 321 2.2E-107 T 12-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 TL08_02315 9a099d1a67cbc2519ba10970ac3d80c2 321 Pfam PF01619 Proline dehydrogenase 59 309 1.7E-32 T 12-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 TL08_26865 d6bb77c9f808e68c2b354cb421896863 456 SUPERFAMILY SSF48024 19 130 9.02E-38 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 TL08_26865 d6bb77c9f808e68c2b354cb421896863 456 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 21 454 1.0E-162 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 TL08_26865 d6bb77c9f808e68c2b354cb421896863 456 Gene3D G3DSA:1.10.860.10 16 179 2.7E-60 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal TL08_26865 d6bb77c9f808e68c2b354cb421896863 456 Pfam PF03796 DnaB-like helicase C terminal domain 198 451 1.7E-102 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 TL08_26865 d6bb77c9f808e68c2b354cb421896863 456 Gene3D G3DSA:3.40.50.300 181 456 1.1E-101 T 12-10-2018 TL08_26865 d6bb77c9f808e68c2b354cb421896863 456 SUPERFAMILY SSF52540 198 441 1.18E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26865 d6bb77c9f808e68c2b354cb421896863 456 Pfam PF00772 DnaB-like helicase N terminal domain 20 122 2.4E-34 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 TL08_26865 d6bb77c9f808e68c2b354cb421896863 456 SMART SM00382 215 412 9.1E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17080 6260ca4e5494e34c120e3e120102f676 459 Gene3D G3DSA:3.30.565.10 205 352 1.3E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_17080 6260ca4e5494e34c120e3e120102f676 459 SMART SM00387 239 353 0.0084 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_17080 6260ca4e5494e34c120e3e120102f676 459 SUPERFAMILY SSF55874 226 350 1.15E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_14125 e88668887054d7265ef9198938e18fd0 304 Gene3D G3DSA:2.30.110.10 2 134 4.8E-46 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_14125 e88668887054d7265ef9198938e18fd0 304 Gene3D G3DSA:1.20.120.520 135 291 5.1E-19 T 12-10-2018 TL08_14125 e88668887054d7265ef9198938e18fd0 304 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 24 133 2.1E-32 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_14125 e88668887054d7265ef9198938e18fd0 304 Pfam PF04075 F420H(2)-dependent quinone reductase 11 133 4.5E-39 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_14125 e88668887054d7265ef9198938e18fd0 304 Pfam PF01814 Hemerythrin HHE cation binding domain 148 288 8.2E-19 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TL08_25095 99fd9d38840a7a786658b1afb259c1b6 406 Pfam PF12698 ABC-2 family transporter protein 33 382 2.6E-46 T 12-10-2018 TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 Gene3D G3DSA:3.40.50.920 610 798 2.8E-78 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 Pfam PF09364 XFP N-terminal domain 12 387 1.3E-176 T 12-10-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 ProSitePatterns PS60003 Phosphoketolase signature 2. 160 178 - T 12-10-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 402 579 5.1E-88 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 SUPERFAMILY SSF52518 379 593 9.81E-27 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 SUPERFAMILY SSF52518 6 372 2.39E-72 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 PIRSF PIRSF017245 3 793 0.0 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 ProSitePatterns PS60002 Phosphoketolase signature 1. 147 153 - T 12-10-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 Pfam PF09363 XFP C-terminal domain 590 791 7.2E-91 T 12-10-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 Gene3D G3DSA:3.40.50.970 2 388 7.8E-169 T 12-10-2018 TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 Hamap MF_01403 Probable phosphoketolase. 8 793 39.968 T 12-10-2018 IPR023962 Probable phosphoketolase TL08_08005 15a4a95175eb1c7f17cc09684a67643f 798 Gene3D G3DSA:3.40.50.970 389 609 7.1E-104 T 12-10-2018 TL08_10020 dcd23c6f441847ee3112327863a49dfa 287 SUPERFAMILY SSF53474 20 282 1.61E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10020 dcd23c6f441847ee3112327863a49dfa 287 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 30 38 2.8E-8 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TL08_10020 dcd23c6f441847ee3112327863a49dfa 287 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 56 67 2.8E-8 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TL08_10020 dcd23c6f441847ee3112327863a49dfa 287 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 96 110 2.8E-8 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TL08_10020 dcd23c6f441847ee3112327863a49dfa 287 Gene3D G3DSA:3.40.50.1820 6 283 1.0E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10020 dcd23c6f441847ee3112327863a49dfa 287 Pfam PF00561 alpha/beta hydrolase fold 30 264 8.6E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_13530 2d0990806270b44ef309d1992ed554dc 309 Gene3D G3DSA:2.20.25.650 177 263 1.7E-13 T 12-10-2018 TL08_13530 2d0990806270b44ef309d1992ed554dc 309 Pfam PF14517 Tachylectin 50 253 1.1E-20 T 12-10-2018 IPR023294 Tachylectin 2 TL08_13530 2d0990806270b44ef309d1992ed554dc 309 SUPERFAMILY SSF50934 139 259 2.09E-15 T 12-10-2018 IPR036813 Tachylectin 2 superfamily TL08_13530 2d0990806270b44ef309d1992ed554dc 309 Gene3D G3DSA:2.115.10.10 36 169 1.5E-11 T 12-10-2018 TL08_08160 3ab103d4663dc7c86dafea8288ff01da 216 Gene3D G3DSA:3.40.50.300 42 163 7.7E-14 T 12-10-2018 TL08_08160 3ab103d4663dc7c86dafea8288ff01da 216 SUPERFAMILY SSF52540 45 198 1.93E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08160 3ab103d4663dc7c86dafea8288ff01da 216 Pfam PF00005 ABC transporter 45 159 6.9E-5 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_03815 0bf35786b4c0173ca2fc21bf32fbad07 319 SUPERFAMILY SSF46785 7 64 9.62E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_03815 0bf35786b4c0173ca2fc21bf32fbad07 319 PIRSF PIRSF016838 1 57 2.3E-4 T 12-10-2018 IPR028349 Protein PafC TL08_03815 0bf35786b4c0173ca2fc21bf32fbad07 319 PIRSF PIRSF016838 69 319 8.1E-27 T 12-10-2018 IPR028349 Protein PafC TL08_03815 0bf35786b4c0173ca2fc21bf32fbad07 319 Pfam PF08279 HTH domain 9 64 5.3E-12 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TL08_03815 0bf35786b4c0173ca2fc21bf32fbad07 319 Pfam PF13280 WYL domain 143 312 5.2E-36 T 12-10-2018 IPR026881 WYL domain TL08_03815 0bf35786b4c0173ca2fc21bf32fbad07 319 Gene3D G3DSA:1.10.10.10 2 67 3.7E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07930 ce326958998a2068cb96425e40c5ac0d 476 Gene3D G3DSA:3.40.605.10 24 472 2.2E-165 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_07930 ce326958998a2068cb96425e40c5ac0d 476 SUPERFAMILY SSF53720 7 474 3.8E-154 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_07930 ce326958998a2068cb96425e40c5ac0d 476 Pfam PF00171 Aldehyde dehydrogenase family 24 474 3.0E-159 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_07930 ce326958998a2068cb96425e40c5ac0d 476 Gene3D G3DSA:3.40.309.10 256 447 2.2E-165 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_07930 ce326958998a2068cb96425e40c5ac0d 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TL08_07930 ce326958998a2068cb96425e40c5ac0d 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TL08_01990 e87662ccd71f9f95e8bfcd002cadbcf2 163 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 4 156 3.0E-53 T 12-10-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00260+2.3.1.178 TL08_01990 e87662ccd71f9f95e8bfcd002cadbcf2 163 Gene3D G3DSA:3.40.630.30 2 160 1.3E-47 T 12-10-2018 TL08_01990 e87662ccd71f9f95e8bfcd002cadbcf2 163 Pfam PF00583 Acetyltransferase (GNAT) family 36 120 7.3E-14 T 12-10-2018 IPR000182 GNAT domain TL08_01990 e87662ccd71f9f95e8bfcd002cadbcf2 163 SUPERFAMILY SSF55729 5 120 7.09E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_03515 3fbbf6c52dcc99e72a930a5b78674d47 165 Gene3D G3DSA:3.40.50.300 1 121 6.1E-24 T 12-10-2018 TL08_03515 3fbbf6c52dcc99e72a930a5b78674d47 165 Pfam PF13732 Domain of unknown function (DUF4162) 69 155 1.1E-9 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 TL08_03515 3fbbf6c52dcc99e72a930a5b78674d47 165 SUPERFAMILY SSF52540 2 78 6.18E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19275 dcea67b009526a20008114b85ec19630 246 Gene3D G3DSA:3.40.50.720 1 246 1.8E-83 T 12-10-2018 TL08_19275 dcea67b009526a20008114b85ec19630 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_19275 dcea67b009526a20008114b85ec19630 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19275 dcea67b009526a20008114b85ec19630 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19275 dcea67b009526a20008114b85ec19630 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19275 dcea67b009526a20008114b85ec19630 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 2.1E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19275 dcea67b009526a20008114b85ec19630 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.1E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19275 dcea67b009526a20008114b85ec19630 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.1E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19275 dcea67b009526a20008114b85ec19630 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.1E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19275 dcea67b009526a20008114b85ec19630 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.1E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19275 dcea67b009526a20008114b85ec19630 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.1E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19275 dcea67b009526a20008114b85ec19630 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 2.5E-63 T 12-10-2018 TL08_19275 dcea67b009526a20008114b85ec19630 246 SUPERFAMILY SSF51735 7 245 4.37E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16810 c6efc45a895850aabc78c23366be926f 378 Pfam PF05762 VWA domain containing CoxE-like protein 152 370 5.6E-54 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like TL08_16810 c6efc45a895850aabc78c23366be926f 378 SUPERFAMILY SSF53300 215 359 3.34E-17 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_16810 c6efc45a895850aabc78c23366be926f 378 Gene3D G3DSA:3.40.50.410 213 377 2.1E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_16810 c6efc45a895850aabc78c23366be926f 378 SMART SM00327 214 373 4.3E-5 T 12-10-2018 IPR002035 von Willebrand factor, type A TL08_04950 c289eb9860494c23535fd7ec61b3f8ed 179 Gene3D G3DSA:1.10.10.10 18 100 2.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04950 c289eb9860494c23535fd7ec61b3f8ed 179 SUPERFAMILY SSF46785 20 168 6.2E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_04950 c289eb9860494c23535fd7ec61b3f8ed 179 Pfam PF03551 Transcriptional regulator PadR-like family 23 93 5.9E-8 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 59 66 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 142 153 1.9E-19 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 281 290 1.9E-19 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 59 78 1.9E-19 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 293 316 1.9E-19 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 Gene3D G3DSA:3.40.50.1370 145 315 4.7E-71 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 Gene3D G3DSA:3.40.50.1370 18 325 4.7E-71 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 18 153 5.1E-34 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 SUPERFAMILY SSF53671 16 328 1.09E-65 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 163 326 3.5E-24 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 PRINTS PR00102 Ornithine carbamoyltransferase signature 131 145 2.0E-11 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 PRINTS PR00102 Ornithine carbamoyltransferase signature 57 71 2.0E-11 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 PRINTS PR00102 Ornithine carbamoyltransferase signature 90 103 2.0E-11 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_14915 f1a99e1030193f2da270a1cb6a839bf8 329 PRINTS PR00102 Ornithine carbamoyltransferase signature 246 256 2.0E-11 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TL08_03150 60bdfc2b7e7e157140bf228691440e3d 556 Pfam PF05960 Bacterial protein of unknown function (DUF885) 20 546 1.3E-155 T 12-10-2018 IPR010281 Protein of unknown function DUF885 TL08_13740 157e92caefe33cf935885e3d5d211418 547 Gene3D G3DSA:3.40.50.300 12 289 1.6E-53 T 12-10-2018 TL08_13740 157e92caefe33cf935885e3d5d211418 547 Pfam PF00005 ABC transporter 22 187 2.7E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13740 157e92caefe33cf935885e3d5d211418 547 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_13740 157e92caefe33cf935885e3d5d211418 547 Gene3D G3DSA:3.40.50.300 313 546 1.4E-40 T 12-10-2018 TL08_13740 157e92caefe33cf935885e3d5d211418 547 SMART SM00382 29 232 3.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13740 157e92caefe33cf935885e3d5d211418 547 SMART SM00382 374 541 3.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13740 157e92caefe33cf935885e3d5d211418 547 Pfam PF00005 ABC transporter 368 495 8.7E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13740 157e92caefe33cf935885e3d5d211418 547 SUPERFAMILY SSF52540 5 232 4.72E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13740 157e92caefe33cf935885e3d5d211418 547 SUPERFAMILY SSF52540 363 544 5.79E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19335 140bc1051dfd9d0bef57eae4f9561e2d 1092 PRINTS PR00723 Subtilisin serine protease family (S8) signature 428 444 1.6E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_19335 140bc1051dfd9d0bef57eae4f9561e2d 1092 PRINTS PR00723 Subtilisin serine protease family (S8) signature 252 265 1.6E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_19335 140bc1051dfd9d0bef57eae4f9561e2d 1092 PRINTS PR00723 Subtilisin serine protease family (S8) signature 214 233 1.6E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_19335 140bc1051dfd9d0bef57eae4f9561e2d 1092 Pfam PF00082 Subtilase family 214 499 5.1E-55 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_19335 140bc1051dfd9d0bef57eae4f9561e2d 1092 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 429 439 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_19335 140bc1051dfd9d0bef57eae4f9561e2d 1092 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 256 266 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_19335 140bc1051dfd9d0bef57eae4f9561e2d 1092 SUPERFAMILY SSF52743 199 488 1.24E-79 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_19335 140bc1051dfd9d0bef57eae4f9561e2d 1092 Gene3D G3DSA:3.40.50.200 190 490 2.7E-91 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_05585 50e0f438d8ff9c8b8254ca07ab87f1f0 431 SUPERFAMILY SSF88659 116 173 9.35E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_05585 50e0f438d8ff9c8b8254ca07ab87f1f0 431 Pfam PF04542 Sigma-70 region 2 23 86 3.1E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_05585 50e0f438d8ff9c8b8254ca07ab87f1f0 431 SUPERFAMILY SSF88946 18 98 6.28E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_05585 50e0f438d8ff9c8b8254ca07ab87f1f0 431 Gene3D G3DSA:1.10.10.10 124 176 1.2E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05585 50e0f438d8ff9c8b8254ca07ab87f1f0 431 Gene3D G3DSA:1.10.1740.10 3 83 4.2E-5 T 12-10-2018 TL08_05585 50e0f438d8ff9c8b8254ca07ab87f1f0 431 Pfam PF08281 Sigma-70, region 4 124 172 9.9E-9 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_05585 50e0f438d8ff9c8b8254ca07ab87f1f0 431 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 174 1.2E-12 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_05585 50e0f438d8ff9c8b8254ca07ab87f1f0 431 SUPERFAMILY SSF48452 211 418 1.84E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10340 35e84788b069f0e7c3fa85d28b083acb 180 Gene3D G3DSA:3.30.428.10 5 180 7.6E-58 T 12-10-2018 IPR036265 HIT-like superfamily TL08_10340 35e84788b069f0e7c3fa85d28b083acb 180 Pfam PF01230 HIT domain 54 145 1.7E-13 T 12-10-2018 IPR001310 Histidine triad (HIT) protein TL08_10340 35e84788b069f0e7c3fa85d28b083acb 180 SUPERFAMILY SSF54197 17 168 3.56E-42 T 12-10-2018 IPR036265 HIT-like superfamily TL08_10455 0a0b1e50deacbb040a461876daeac752 111 Pfam PF04673 Polyketide synthesis cyclase 2 104 4.7E-40 T 12-10-2018 IPR006765 Polyketide synthesis cyclase GO:0030639 TL08_10455 0a0b1e50deacbb040a461876daeac752 111 Gene3D G3DSA:3.30.70.1090 1 107 4.1E-40 T 12-10-2018 IPR038474 Polyketide synthesis cyclase superfamily TL08_10455 0a0b1e50deacbb040a461876daeac752 111 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 103 8.0E-40 T 12-10-2018 IPR006765 Polyketide synthesis cyclase GO:0030639 TL08_10455 0a0b1e50deacbb040a461876daeac752 111 SUPERFAMILY SSF54909 2 105 1.66E-41 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_09715 016c4609e4dd857d5b2260d986138130 153 Pfam PF00376 MerR family regulatory protein 9 45 1.6E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09715 016c4609e4dd857d5b2260d986138130 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 9.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09715 016c4609e4dd857d5b2260d986138130 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 9.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09715 016c4609e4dd857d5b2260d986138130 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 9.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09715 016c4609e4dd857d5b2260d986138130 153 SUPERFAMILY SSF46955 8 129 2.16E-29 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_09715 016c4609e4dd857d5b2260d986138130 153 Pfam PF09278 MerR, DNA binding 50 115 5.9E-18 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding TL08_09715 016c4609e4dd857d5b2260d986138130 153 SMART SM00422 8 76 1.3E-23 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09715 016c4609e4dd857d5b2260d986138130 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 145 6.1E-59 T 12-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 TL08_09715 016c4609e4dd857d5b2260d986138130 153 Gene3D G3DSA:1.10.1660.10 3 131 4.2E-35 T 12-10-2018 TL08_02330 a54a07104a81f185f71ecca07e0a2b54 348 Gene3D G3DSA:3.40.50.720 1 319 9.2E-42 T 12-10-2018 TL08_02330 a54a07104a81f185f71ecca07e0a2b54 348 SUPERFAMILY SSF51735 1 316 4.44E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_02330 a54a07104a81f185f71ecca07e0a2b54 348 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 189 6.4E-22 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 13 390 1.4E-192 T 12-10-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 Pfam PF01261 Xylose isomerase-like TIM barrel 51 275 2.6E-24 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 SUPERFAMILY SSF51658 15 394 3.04E-115 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 Hamap MF_00455 Xylose isomerase [xylA]. 5 390 34.915 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 Gene3D G3DSA:3.20.20.150 12 394 1.5E-132 T 12-10-2018 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 PRINTS PR00688 Xylose isomerase signature 258 269 2.2E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 PRINTS PR00688 Xylose isomerase signature 139 160 2.2E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 PRINTS PR00688 Xylose isomerase signature 188 212 2.2E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 PRINTS PR00688 Xylose isomerase signature 92 112 2.2E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 PRINTS PR00688 Xylose isomerase signature 115 134 2.2E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 PRINTS PR00688 Xylose isomerase signature 291 302 2.2E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 PRINTS PR00688 Xylose isomerase signature 230 257 2.2E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 PRINTS PR00688 Xylose isomerase signature 55 77 2.2E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_23885 d84aaee5d01c5d3aa608ab9de40ddbf4 395 PRINTS PR00688 Xylose isomerase signature 166 185 2.2E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 TL08_22290 e11e3a886901a09fe47cecd2cd055be7 458 Gene3D G3DSA:3.30.420.40 192 383 8.6E-98 T 12-10-2018 TL08_22290 e11e3a886901a09fe47cecd2cd055be7 458 SUPERFAMILY SSF53067 190 376 6.87E-12 T 12-10-2018 TL08_22290 e11e3a886901a09fe47cecd2cd055be7 458 Gene3D G3DSA:3.30.420.40 43 418 8.6E-98 T 12-10-2018 TL08_22290 e11e3a886901a09fe47cecd2cd055be7 458 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 36 423 32.811 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 TL08_22290 e11e3a886901a09fe47cecd2cd055be7 458 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 37 422 4.9E-95 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 TL08_03295 3494fd26c72f76db98310d5a632e459d 406 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 70 124 4.0E-9 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TL08_03295 3494fd26c72f76db98310d5a632e459d 406 SUPERFAMILY SSF56349 69 392 6.77E-60 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_03295 3494fd26c72f76db98310d5a632e459d 406 Pfam PF00589 Phage integrase family 206 389 3.6E-19 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_03295 3494fd26c72f76db98310d5a632e459d 406 Gene3D G3DSA:1.10.150.130 67 202 7.4E-23 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_03295 3494fd26c72f76db98310d5a632e459d 406 Gene3D G3DSA:1.10.443.10 203 401 1.1E-46 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TL08_07245 1ab937f78130e86faf50683135f91a9b 375 SUPERFAMILY SSF53686 26 360 1.83E-103 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_07245 1ab937f78130e86faf50683135f91a9b 375 PIRSF PIRSF038945 17 374 1.5E-166 T 12-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TL08_07245 1ab937f78130e86faf50683135f91a9b 375 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 76 89 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TL08_07245 1ab937f78130e86faf50683135f91a9b 375 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 48 342 2.4E-76 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_07245 1ab937f78130e86faf50683135f91a9b 375 Gene3D G3DSA:3.40.50.1100 35 348 1.4E-123 T 12-10-2018 TL08_07245 1ab937f78130e86faf50683135f91a9b 375 TIGRFAM TIGR00260 thrC: threonine synthase 36 349 6.4E-91 T 12-10-2018 IPR004450 Threonine synthase-like TL08_07245 1ab937f78130e86faf50683135f91a9b 375 Gene3D G3DSA:3.40.50.1100 84 180 1.4E-123 T 12-10-2018 TL08_10960 444f90805849a6a0815aea7fcdb67ace 325 SUPERFAMILY SSF51735 103 284 8.79E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_10960 444f90805849a6a0815aea7fcdb67ace 325 Gene3D G3DSA:3.40.50.720 31 321 7.9E-94 T 12-10-2018 TL08_10960 444f90805849a6a0815aea7fcdb67ace 325 Gene3D G3DSA:3.40.50.720 102 290 7.9E-94 T 12-10-2018 TL08_10960 444f90805849a6a0815aea7fcdb67ace 325 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 284 2.6E-49 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TL08_10960 444f90805849a6a0815aea7fcdb67ace 325 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TL08_10960 444f90805849a6a0815aea7fcdb67ace 325 SUPERFAMILY SSF52283 39 132 5.95E-9 T 12-10-2018 TL08_00745 22af72f31f2f71bb1c247f00a30ab4e6 509 Pfam PF02225 PA domain 143 229 4.5E-15 T 12-10-2018 IPR003137 PA domain TL08_00745 22af72f31f2f71bb1c247f00a30ab4e6 509 SUPERFAMILY SSF52025 109 223 6.41E-17 T 12-10-2018 TL08_00745 22af72f31f2f71bb1c247f00a30ab4e6 509 Gene3D G3DSA:3.50.30.30 114 243 3.9E-79 T 12-10-2018 TL08_00745 22af72f31f2f71bb1c247f00a30ab4e6 509 Pfam PF04389 Peptidase family M28 252 466 9.7E-37 T 12-10-2018 IPR007484 Peptidase M28 TL08_00745 22af72f31f2f71bb1c247f00a30ab4e6 509 SUPERFAMILY SSF53187 51 470 9.34E-55 T 12-10-2018 TL08_00745 22af72f31f2f71bb1c247f00a30ab4e6 509 Gene3D G3DSA:3.40.630.10 75 461 3.9E-79 T 12-10-2018 TL08_04905 52438d5a64daabe807bbe1928b9c47d3 377 SUPERFAMILY SSF69572 125 342 7.19E-14 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TL08_04905 52438d5a64daabe807bbe1928b9c47d3 377 Gene3D G3DSA:3.40.50.720 171 342 3.9E-20 T 12-10-2018 TL08_04905 52438d5a64daabe807bbe1928b9c47d3 377 Pfam PF00899 ThiF family 119 339 4.7E-11 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TL08_06715 ac4c4f1e6228754126de9124216ce122 436 SMART SM00825 Beta-ketoacyl synthase 20 436 1.0E-12 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_06715 ac4c4f1e6228754126de9124216ce122 436 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 18 268 7.7E-28 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_06715 ac4c4f1e6228754126de9124216ce122 436 Gene3D G3DSA:3.40.47.10 22 284 1.7E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_06715 ac4c4f1e6228754126de9124216ce122 436 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 280 393 4.3E-31 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_06715 ac4c4f1e6228754126de9124216ce122 436 Gene3D G3DSA:3.40.47.10 285 436 4.3E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_06715 ac4c4f1e6228754126de9124216ce122 436 SUPERFAMILY SSF53901 18 278 1.43E-38 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_06715 ac4c4f1e6228754126de9124216ce122 436 SUPERFAMILY SSF53901 240 432 1.29E-58 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_20505 3e4af0f78e4a83d0b54670c3f9ad6728 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 407 1.9E-89 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TL08_20505 3e4af0f78e4a83d0b54670c3f9ad6728 424 SUPERFAMILY SSF55681 7 348 1.57E-67 T 12-10-2018 TL08_20505 3e4af0f78e4a83d0b54670c3f9ad6728 424 PIRSF PIRSF001549 2 413 2.3E-95 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TL08_20505 3e4af0f78e4a83d0b54670c3f9ad6728 424 Pfam PF13393 Histidyl-tRNA synthetase 10 341 6.5E-48 T 12-10-2018 TL08_20505 3e4af0f78e4a83d0b54670c3f9ad6728 424 Gene3D G3DSA:3.30.930.10 3 347 3.7E-96 T 12-10-2018 TL08_10625 06e808bb5b03888a6d2c8b3fbd193821 268 Pfam PF00089 Trypsin 44 259 1.9E-53 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_10625 06e808bb5b03888a6d2c8b3fbd193821 268 Gene3D G3DSA:2.40.10.10 56 258 8.8E-71 T 12-10-2018 TL08_10625 06e808bb5b03888a6d2c8b3fbd193821 268 SUPERFAMILY SSF50494 42 267 4.71E-65 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_10625 06e808bb5b03888a6d2c8b3fbd193821 268 Gene3D G3DSA:2.40.10.10 44 256 8.8E-71 T 12-10-2018 TL08_10625 06e808bb5b03888a6d2c8b3fbd193821 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 216 228 6.3E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_10625 06e808bb5b03888a6d2c8b3fbd193821 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 71 86 6.3E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_10625 06e808bb5b03888a6d2c8b3fbd193821 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 127 141 6.3E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_10625 06e808bb5b03888a6d2c8b3fbd193821 268 SMART SM00020 43 262 7.9E-68 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_10625 06e808bb5b03888a6d2c8b3fbd193821 268 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 217 228 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site TL08_13525 bc6b0a52546f43790d63281296a44f8d 227 Pfam PF01738 Dienelactone hydrolase family 87 198 2.6E-6 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TL08_13525 bc6b0a52546f43790d63281296a44f8d 227 SUPERFAMILY SSF53474 5 215 2.2E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13525 bc6b0a52546f43790d63281296a44f8d 227 Gene3D G3DSA:3.40.50.1820 3 213 1.5E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_00020 50a357647d948b93d9f87d5c92fbb665 387 Gene3D G3DSA:1.20.1050.90 120 328 1.7E-87 T 12-10-2018 TL08_00020 50a357647d948b93d9f87d5c92fbb665 387 ProSitePatterns PS00618 RecF protein signature 2. 329 347 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 TL08_00020 50a357647d948b93d9f87d5c92fbb665 387 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 361 4.7E-14 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TL08_00020 50a357647d948b93d9f87d5c92fbb665 387 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 387 90.035 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TL08_00020 50a357647d948b93d9f87d5c92fbb665 387 Gene3D G3DSA:3.40.50.300 6 361 1.7E-87 T 12-10-2018 TL08_00020 50a357647d948b93d9f87d5c92fbb665 387 SUPERFAMILY SSF52540 1 350 6.38E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_00020 50a357647d948b93d9f87d5c92fbb665 387 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 369 1.4E-107 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TL08_07295 208260a49f8efefe974e1dadc5c4ee28 388 Pfam PF00953 Glycosyl transferase family 4 94 259 7.2E-30 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 Pfam PF00012 Hsp70 protein 108 355 1.7E-26 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 311 325 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 Gene3D G3DSA:3.30.420.40 159 339 3.4E-86 T 12-10-2018 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 Gene3D G3DSA:3.30.420.40 5 350 3.4E-86 T 12-10-2018 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 Gene3D G3DSA:3.90.640.10 202 289 3.4E-86 T 12-10-2018 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 SUPERFAMILY SSF53067 2 152 8.09E-20 T 12-10-2018 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 PRINTS PR00301 70kDa heat shock protein signature 176 186 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 PRINTS PR00301 70kDa heat shock protein signature 308 324 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 PRINTS PR00301 70kDa heat shock protein signature 339 359 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 SUPERFAMILY SSF53067 168 354 3.14E-35 T 12-10-2018 TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 501 640 7.0E-24 T 12-10-2018 IPR023840 Type VII secretion system Rv3446c TL08_24945 fbd029d7918b69c907fafcb9ad0f872d 642 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 170 183 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TL08_14615 5cb06359920aa10c7320b4eb37c054d1 449 SMART SM00829 49 415 1.9E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_14615 5cb06359920aa10c7320b4eb37c054d1 449 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 67 190 5.5E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_14615 5cb06359920aa10c7320b4eb37c054d1 449 Pfam PF00107 Zinc-binding dehydrogenase 236 379 1.2E-34 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_14615 5cb06359920aa10c7320b4eb37c054d1 449 Gene3D G3DSA:3.90.180.10 11 432 1.6E-206 T 12-10-2018 TL08_14615 5cb06359920aa10c7320b4eb37c054d1 449 SUPERFAMILY SSF50129 50 230 6.78E-29 T 12-10-2018 IPR011032 GroES-like superfamily TL08_14615 5cb06359920aa10c7320b4eb37c054d1 449 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 32 428 6.7E-171 T 12-10-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 TL08_14615 5cb06359920aa10c7320b4eb37c054d1 449 Gene3D G3DSA:3.40.50.720 219 365 1.6E-206 T 12-10-2018 TL08_14615 5cb06359920aa10c7320b4eb37c054d1 449 SUPERFAMILY SSF51735 195 386 1.43E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05530 b134a4ce00453ae23426f1ac95c07550 224 Gene3D G3DSA:3.40.50.2300 2 127 7.2E-37 T 12-10-2018 TL08_05530 b134a4ce00453ae23426f1ac95c07550 224 Gene3D G3DSA:1.10.10.10 128 224 1.8E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05530 b134a4ce00453ae23426f1ac95c07550 224 Pfam PF00072 Response regulator receiver domain 5 112 1.4E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_05530 b134a4ce00453ae23426f1ac95c07550 224 SUPERFAMILY SSF52172 4 183 3.08E-43 T 12-10-2018 IPR011006 CheY-like superfamily TL08_05530 b134a4ce00453ae23426f1ac95c07550 224 SMART SM00862 145 221 4.9E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_05530 b134a4ce00453ae23426f1ac95c07550 224 SMART SM00448 2 112 1.9E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_05530 b134a4ce00453ae23426f1ac95c07550 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 221 2.9E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_14745 5bf3566989a4f0c6be9a9ae9359d26ee 190 Gene3D G3DSA:1.10.357.10 8 189 3.2E-50 T 12-10-2018 TL08_14745 5bf3566989a4f0c6be9a9ae9359d26ee 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14745 5bf3566989a4f0c6be9a9ae9359d26ee 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14745 5bf3566989a4f0c6be9a9ae9359d26ee 190 SUPERFAMILY SSF48498 75 189 1.26E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_14745 5bf3566989a4f0c6be9a9ae9359d26ee 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 9.0E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14745 5bf3566989a4f0c6be9a9ae9359d26ee 190 SUPERFAMILY SSF46689 3 74 7.7E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 SMART SM00028 572 605 0.079 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 SMART SM00028 452 485 0.075 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 SMART SM00028 492 525 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 Gene3D G3DSA:1.25.40.10 525 624 4.9E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 Pfam PF13424 Tetratricopeptide repeat 538 602 3.4E-8 T 12-10-2018 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 SUPERFAMILY SSF48452 492 603 4.48E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 Gene3D G3DSA:1.25.40.10 371 524 1.0E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 SUPERFAMILY SSF48452 420 521 2.4E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 SUPERFAMILY SSF52540 2 224 8.4E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 Pfam PF00931 NB-ARC domain 2 225 2.6E-13 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_20030 759ef635cf4a9fcea0bdc1fff8bed773 646 Gene3D G3DSA:3.40.50.300 1 122 3.5E-15 T 12-10-2018 TL08_05295 6283a87e0505e7ba831d32b5ab6c4930 243 Pfam PF12730 ABC-2 family transporter protein 21 142 7.7E-7 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TL08_01520 4b2945cfea5b93f3ece248522b3eebbd 412 SUPERFAMILY SSF52540 18 234 1.32E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01520 4b2945cfea5b93f3ece248522b3eebbd 412 Pfam PF13177 DNA polymerase III, delta subunit 46 195 2.7E-34 T 12-10-2018 TL08_01520 4b2945cfea5b93f3ece248522b3eebbd 412 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 46 230 2.5E-54 T 12-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_01520 4b2945cfea5b93f3ece248522b3eebbd 412 Gene3D G3DSA:3.40.50.300 7 195 7.7E-45 T 12-10-2018 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 ProSitePatterns PS00480 Citrate synthase signature. 268 280 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 Pfam PF00285 Citrate synthase, C-terminal domain 14 369 5.9E-106 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 SUPERFAMILY SSF48256 11 384 4.19E-106 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 PIRSF PIRSF001369 6 386 4.1E-103 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 Gene3D G3DSA:1.10.580.10 26 360 4.1E-105 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 PRINTS PR00143 Citrate synthase signature 186 201 5.7E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 PRINTS PR00143 Citrate synthase signature 208 236 5.7E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 PRINTS PR00143 Citrate synthase signature 320 336 5.7E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 PRINTS PR00143 Citrate synthase signature 261 281 5.7E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 PRINTS PR00143 Citrate synthase signature 137 150 5.7E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 PRINTS PR00143 Citrate synthase signature 340 354 5.7E-34 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_13225 f19188e6af3deb571ab7f31f67cd4bf9 389 Gene3D G3DSA:1.10.230.10 234 334 4.1E-105 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain TL08_17115 fe6a152c6028c8fcdedb1028c8d12676 519 Gene3D G3DSA:1.10.630.10 67 465 2.0E-82 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17115 fe6a152c6028c8fcdedb1028c8d12676 519 SUPERFAMILY SSF48264 61 459 2.36E-62 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17115 fe6a152c6028c8fcdedb1028c8d12676 519 PRINTS PR00359 B-class P450 signature 256 278 7.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17115 fe6a152c6028c8fcdedb1028c8d12676 519 PRINTS PR00359 B-class P450 signature 397 406 7.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17115 fe6a152c6028c8fcdedb1028c8d12676 519 PRINTS PR00359 B-class P450 signature 406 417 7.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17115 fe6a152c6028c8fcdedb1028c8d12676 519 PRINTS PR00359 B-class P450 signature 159 170 7.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17115 fe6a152c6028c8fcdedb1028c8d12676 519 PRINTS PR00359 B-class P450 signature 205 221 7.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17115 fe6a152c6028c8fcdedb1028c8d12676 519 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 399 408 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_02850 bd9bde2b3237f8ed432d36a20c3fe2cd 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 2.2E-20 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02850 bd9bde2b3237f8ed432d36a20c3fe2cd 54 SUPERFAMILY SSF57829 4 54 3.6E-18 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TL08_02850 bd9bde2b3237f8ed432d36a20c3fe2cd 54 Gene3D G3DSA:2.20.28.120 2 54 3.9E-23 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02850 bd9bde2b3237f8ed432d36a20c3fe2cd 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 18.93 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_02850 bd9bde2b3237f8ed432d36a20c3fe2cd 54 Pfam PF00471 Ribosomal protein L33 9 54 2.9E-21 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_09520 66fac61f70a6075cae751f73441dc757 274 Gene3D G3DSA:3.20.20.370 25 273 3.8E-95 T 12-10-2018 TL08_09520 66fac61f70a6075cae751f73441dc757 274 Pfam PF03746 LamB/YcsF family 26 263 2.5E-98 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TL08_09520 66fac61f70a6075cae751f73441dc757 274 SUPERFAMILY SSF88713 26 269 2.82E-94 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TL08_09520 66fac61f70a6075cae751f73441dc757 274 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 24 268 42.981 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TL08_13515 e732340bbfcc62355979d36d930271e5 223 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 37 219 3.5E-33 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal TL08_13515 e732340bbfcc62355979d36d930271e5 223 SUPERFAMILY SSF81296 37 222 3.36E-34 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_13515 e732340bbfcc62355979d36d930271e5 223 Gene3D G3DSA:2.70.50.50 37 222 2.3E-70 T 12-10-2018 TL08_10865 54dc1531d2928c76894b171b6ebeded3 311 Pfam PF00892 EamA-like transporter family 17 143 3.0E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_10865 54dc1531d2928c76894b171b6ebeded3 311 Pfam PF00892 EamA-like transporter family 154 289 2.2E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_10865 54dc1531d2928c76894b171b6ebeded3 311 SUPERFAMILY SSF103481 192 293 3.66E-11 T 12-10-2018 TL08_10865 54dc1531d2928c76894b171b6ebeded3 311 SUPERFAMILY SSF103481 44 146 1.1E-13 T 12-10-2018 TL08_02140 fa6de981592f74d15fc046fab168188c 276 Gene3D G3DSA:1.10.3720.10 1 267 3.6E-67 T 12-10-2018 IPR035906 MetI-like superfamily TL08_02140 fa6de981592f74d15fc046fab168188c 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 269 2.1E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_02140 fa6de981592f74d15fc046fab168188c 276 SUPERFAMILY SSF161098 2 276 1.5E-76 T 12-10-2018 IPR035906 MetI-like superfamily TL08_14795 03f3065d23710baf62a7f4456b45113a 275 SUPERFAMILY SSF52540 13 260 2.22E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14795 03f3065d23710baf62a7f4456b45113a 275 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_14795 03f3065d23710baf62a7f4456b45113a 275 SMART SM00382 40 238 4.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_14795 03f3065d23710baf62a7f4456b45113a 275 Gene3D G3DSA:3.40.50.300 10 275 4.6E-81 T 12-10-2018 TL08_14795 03f3065d23710baf62a7f4456b45113a 275 Pfam PF00005 ABC transporter 32 188 2.1E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_19755 96bf9fac62bd1f03cd22b3680bf700b7 153 SMART SM00347 26 126 6.6E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_19755 96bf9fac62bd1f03cd22b3680bf700b7 153 Pfam PF12802 MarR family 31 85 4.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_19755 96bf9fac62bd1f03cd22b3680bf700b7 153 SUPERFAMILY SSF46785 5 141 1.46E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_19755 96bf9fac62bd1f03cd22b3680bf700b7 153 Gene3D G3DSA:1.10.10.10 2 144 6.1E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22955 84714c2d975bf174a85d0e4579c8ff79 142 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 100 116 1.2E-5 T 12-10-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 TL08_22955 84714c2d975bf174a85d0e4579c8ff79 142 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 38 64 1.2E-5 T 12-10-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 TL08_22955 84714c2d975bf174a85d0e4579c8ff79 142 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 117 133 1.2E-5 T 12-10-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 TL08_22955 84714c2d975bf174a85d0e4579c8ff79 142 ProSitePatterns PS00999 Streptomyces subtilisin-type inhibitors signature. 67 84 - T 12-10-2018 IPR020054 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor, conserved site GO:0004867 TL08_22955 84714c2d975bf174a85d0e4579c8ff79 142 SUPERFAMILY SSF55399 38 142 4.84E-26 T 12-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 TL08_22955 84714c2d975bf174a85d0e4579c8ff79 142 Pfam PF00720 Subtilisin inhibitor-like 38 128 1.0E-22 T 12-10-2018 IPR023549 Subtilisin inhibitor GO:0004867 TL08_22955 84714c2d975bf174a85d0e4579c8ff79 142 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 41 132 2.0E-12 T 12-10-2018 IPR023549 Subtilisin inhibitor GO:0004867 TL08_22955 84714c2d975bf174a85d0e4579c8ff79 142 Gene3D G3DSA:3.30.350.10 34 142 1.6E-32 T 12-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 TL08_14905 2e9b1b8cfb7c807e27b3516268dd09c9 453 Pfam PF01554 MatE 244 400 5.0E-11 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TL08_05365 d9d74863470576f8e3ef758ea2dba918 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 4.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05365 d9d74863470576f8e3ef758ea2dba918 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 4.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05365 d9d74863470576f8e3ef758ea2dba918 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 4.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05365 d9d74863470576f8e3ef758ea2dba918 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 4.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05365 d9d74863470576f8e3ef758ea2dba918 314 Gene3D G3DSA:3.40.50.720 6 313 1.9E-64 T 12-10-2018 TL08_05365 d9d74863470576f8e3ef758ea2dba918 314 Pfam PF00106 short chain dehydrogenase 16 217 4.5E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05365 d9d74863470576f8e3ef758ea2dba918 314 SUPERFAMILY SSF51735 13 264 2.54E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_01125 3d6522a9e26e645c49e9af0775c47352 207 SUPERFAMILY SSF55469 19 205 4.45E-36 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_01125 3d6522a9e26e645c49e9af0775c47352 207 Pfam PF00881 Nitroreductase family 26 81 8.3E-8 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TL08_01125 3d6522a9e26e645c49e9af0775c47352 207 Pfam PF00881 Nitroreductase family 113 168 8.4E-7 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TL08_01125 3d6522a9e26e645c49e9af0775c47352 207 Gene3D G3DSA:3.40.109.10 11 205 1.6E-40 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_20675 920cce30eaaf4f9d9d2fc9c3e80d89d4 378 Gene3D G3DSA:3.30.360.10 141 283 2.2E-20 T 12-10-2018 TL08_20675 920cce30eaaf4f9d9d2fc9c3e80d89d4 378 SUPERFAMILY SSF55347 137 303 1.59E-12 T 12-10-2018 TL08_20675 920cce30eaaf4f9d9d2fc9c3e80d89d4 378 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 127 9.5E-18 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_20675 920cce30eaaf4f9d9d2fc9c3e80d89d4 378 SUPERFAMILY SSF51735 4 155 1.83E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_20675 920cce30eaaf4f9d9d2fc9c3e80d89d4 378 Gene3D G3DSA:3.40.50.720 2 140 6.1E-30 T 12-10-2018 TL08_16580 116b354ae864714542774904d6f1e761 187 SMART SM00418 26 112 0.0016 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_16580 116b354ae864714542774904d6f1e761 187 SUPERFAMILY SSF46785 27 163 1.9E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16580 116b354ae864714542774904d6f1e761 187 Pfam PF12840 Helix-turn-helix domain 29 81 9.3E-13 T 12-10-2018 TL08_16580 116b354ae864714542774904d6f1e761 187 Gene3D G3DSA:1.10.10.10 17 99 2.5E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19880 a335d4748cec0a3b238eca42db656778 502 Pfam PF07690 Major Facilitator Superfamily 23 410 2.2E-41 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_19880 a335d4748cec0a3b238eca42db656778 502 SUPERFAMILY SSF103473 6 480 1.57E-53 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_19880 a335d4748cec0a3b238eca42db656778 502 Gene3D G3DSA:1.20.1250.20 265 499 5.5E-13 T 12-10-2018 TL08_19880 a335d4748cec0a3b238eca42db656778 502 Gene3D G3DSA:1.20.1720.10 16 246 5.9E-37 T 12-10-2018 TL08_06145 028baf76ac7db938ef1682f966210855 288 Gene3D G3DSA:1.10.260.40 6 72 2.4E-10 T 12-10-2018 TL08_06145 028baf76ac7db938ef1682f966210855 288 Pfam PF13560 Helix-turn-helix domain 15 76 2.1E-12 T 12-10-2018 TL08_06145 028baf76ac7db938ef1682f966210855 288 SMART SM00530 19 74 2.5E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_06145 028baf76ac7db938ef1682f966210855 288 SUPERFAMILY SSF47413 14 70 1.56E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_12180 d5efd0178a04ceb29a271d1c4415eed0 213 Pfam PF08044 Domain of unknown function (DUF1707) 11 63 5.7E-21 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 Pfam PF02983 Alpha-lytic protease prodomain 127 183 2.9E-10 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 Gene3D G3DSA:2.40.10.10 272 370 1.3E-71 T 12-10-2018 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 324 347 2.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 348 362 2.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 284 304 2.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 224 238 2.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 305 322 2.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 SUPERFAMILY SSF50494 203 379 5.83E-34 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 Gene3D G3DSA:2.40.10.10 204 381 1.3E-71 T 12-10-2018 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 PIRSF PIRSF001134 2 385 5.2E-123 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 Gene3D G3DSA:3.30.300.50 124 195 1.6E-6 T 12-10-2018 IPR035070 Streptogrisin prodomain TL08_02120 2d1f17b6efa2b0ff2dbed2f3affb0f3c 385 Gene3D G3DSA:3.30.300.50 42 118 1.0E-9 T 12-10-2018 IPR035070 Streptogrisin prodomain TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 Gene3D G3DSA:3.30.1330.10 68 222 1.1E-122 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 SUPERFAMILY SSF55326 444 611 7.07E-58 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 SUPERFAMILY SSF56042 230 471 2.54E-49 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 784 303.863 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 SUPERFAMILY SSF56042 618 783 8.2E-35 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 SUPERFAMILY SSF55326 39 221 5.53E-49 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 Gene3D G3DSA:3.90.650.10 616 784 1.7E-35 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 Pfam PF00586 AIR synthase related protein, N-terminal domain 486 604 1.6E-24 T 12-10-2018 IPR016188 PurM-like, N-terminal domain TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 Pfam PF00586 AIR synthase related protein, N-terminal domain 116 217 5.1E-22 T 12-10-2018 IPR016188 PurM-like, N-terminal domain TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 Pfam PF02769 AIR synthase related protein, C-terminal domain 231 387 7.6E-32 T 12-10-2018 IPR010918 PurM-like, C-terminal domain TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 Pfam PF02769 AIR synthase related protein, C-terminal domain 619 756 3.8E-17 T 12-10-2018 IPR010918 PurM-like, C-terminal domain TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 Gene3D G3DSA:3.30.1330.10 434 608 3.9E-58 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 43 780 2.2E-247 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 PIRSF PIRSF001587 20 784 6.7E-279 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_26045 10155e3277bea8b13bc59bfe5cd005df 784 Gene3D G3DSA:3.90.650.10 54 407 1.1E-122 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TL08_24295 af60afbc5dfa7485b65ecb634d2102d7 327 SMART SM01133 68 308 4.5E-66 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TL08_24295 af60afbc5dfa7485b65ecb634d2102d7 327 Gene3D G3DSA:3.20.20.70 58 311 1.3E-83 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_24295 af60afbc5dfa7485b65ecb634d2102d7 327 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 70 289 4.1E-51 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TL08_24295 af60afbc5dfa7485b65ecb634d2102d7 327 Pfam PF01791 DeoC/LacD family aldolase 65 302 7.2E-23 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TL08_24295 af60afbc5dfa7485b65ecb634d2102d7 327 SUPERFAMILY SSF51569 66 307 3.66E-70 T 12-10-2018 TL08_24295 af60afbc5dfa7485b65ecb634d2102d7 327 PIRSF PIRSF001357 63 317 2.4E-74 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TL08_08070 2e0049a41b590a2028f02b52023c4786 302 Pfam PF00756 Putative esterase 77 258 3.3E-7 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TL08_08070 2e0049a41b590a2028f02b52023c4786 302 SUPERFAMILY SSF53474 68 301 6.99E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_08070 2e0049a41b590a2028f02b52023c4786 302 Gene3D G3DSA:3.40.50.1820 69 299 1.9E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16130 c98cf2f015f7806625006b3bc6342ea7 244 SUPERFAMILY SSF52540 2 215 1.55E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_16130 c98cf2f015f7806625006b3bc6342ea7 244 SMART SM00382 26 204 9.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_16130 c98cf2f015f7806625006b3bc6342ea7 244 Gene3D G3DSA:3.40.50.300 1 226 5.6E-52 T 12-10-2018 TL08_16130 c98cf2f015f7806625006b3bc6342ea7 244 Pfam PF00005 ABC transporter 17 156 7.0E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_19710 51e8a66db563fa246335fbb2e76d9034 157 Gene3D G3DSA:3.30.530.20 1 157 1.4E-40 T 12-10-2018 IPR023393 START-like domain superfamily TL08_19710 51e8a66db563fa246335fbb2e76d9034 157 SUPERFAMILY SSF55961 12 154 2.06E-37 T 12-10-2018 TL08_19710 51e8a66db563fa246335fbb2e76d9034 157 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 25 154 3.8E-19 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TL08_10820 5d83ce90941869902929a9e6a8ea2fc7 237 Pfam PF07510 Protein of unknown function (DUF1524) 133 231 6.3E-8 T 12-10-2018 IPR011089 Domain of unknown function DUF1524 TL08_07450 415d643babd56eade8b3a873b14e2f8b 262 Pfam PF12697 Alpha/beta hydrolase family 12 248 1.4E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_07450 415d643babd56eade8b3a873b14e2f8b 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 3.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_07450 415d643babd56eade8b3a873b14e2f8b 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 3.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_07450 415d643babd56eade8b3a873b14e2f8b 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 3.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_07450 415d643babd56eade8b3a873b14e2f8b 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 35 50 3.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_07450 415d643babd56eade8b3a873b14e2f8b 262 SUPERFAMILY SSF53474 6 257 1.34E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07450 415d643babd56eade8b3a873b14e2f8b 262 Gene3D G3DSA:3.40.50.1820 3 259 1.0E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 26 36 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 Pfam PF00162 Phosphoglycerate kinase 23 401 6.7E-142 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 Gene3D G3DSA:3.40.50.1260 187 401 6.1E-140 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 SUPERFAMILY SSF53748 21 411 1.77E-139 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PIRSF PIRSF000724 8 411 4.1E-132 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PRINTS PR00477 Phosphoglycerate kinase family signature 120 135 1.8E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PRINTS PR00477 Phosphoglycerate kinase family signature 21 37 1.8E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PRINTS PR00477 Phosphoglycerate kinase family signature 185 207 1.8E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PRINTS PR00477 Phosphoglycerate kinase family signature 387 404 1.8E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PRINTS PR00477 Phosphoglycerate kinase family signature 208 227 1.8E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PRINTS PR00477 Phosphoglycerate kinase family signature 363 374 1.8E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PRINTS PR00477 Phosphoglycerate kinase family signature 330 355 1.8E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PRINTS PR00477 Phosphoglycerate kinase family signature 42 64 1.8E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 PRINTS PR00477 Phosphoglycerate kinase family signature 155 177 1.8E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 16 411 40.57 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11630 c985913c8a3450ba6eb9d85a5cab946f 411 Gene3D G3DSA:3.40.50.1260 23 409 6.1E-140 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_16935 955228985e9d807cc02f5da4f6a97e66 387 Gene3D G3DSA:2.40.50.940 222 357 3.0E-28 T 12-10-2018 TL08_16935 955228985e9d807cc02f5da4f6a97e66 387 Gene3D G3DSA:2.40.50.140 289 348 3.0E-28 T 12-10-2018 TL08_16935 955228985e9d807cc02f5da4f6a97e66 387 Pfam PF08402 TOBE domain 282 356 1.1E-9 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TL08_16935 955228985e9d807cc02f5da4f6a97e66 387 SMART SM00382 28 211 1.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_16935 955228985e9d807cc02f5da4f6a97e66 387 SUPERFAMILY SSF52540 4 242 1.54E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_16935 955228985e9d807cc02f5da4f6a97e66 387 Gene3D G3DSA:3.40.50.300 3 221 5.2E-59 T 12-10-2018 TL08_16935 955228985e9d807cc02f5da4f6a97e66 387 Pfam PF00005 ABC transporter 20 161 3.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_16935 955228985e9d807cc02f5da4f6a97e66 387 SUPERFAMILY SSF50331 236 364 1.02E-24 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TL08_16935 955228985e9d807cc02f5da4f6a97e66 387 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 Gene3D G3DSA:2.70.150.20 141 245 1.2E-24 T 12-10-2018 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 37 729 39.277 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 Pfam PF00122 E1-E2 ATPase 150 316 1.3E-33 T 12-10-2018 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 Pfam PF00702 haloacid dehalogenase-like hydrolase 334 579 1.5E-33 T 12-10-2018 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 SUPERFAMILY SSF56784 326 608 1.62E-38 T 12-10-2018 IPR036412 HAD-like superfamily TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 SUPERFAMILY SSF81653 151 240 1.31E-19 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 SUPERFAMILY SSF81660 349 500 1.08E-23 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 39 725 5.3E-285 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 SUPERFAMILY SSF81665 58 332 3.01E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 490 501 7.1E-26 T 12-10-2018 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 187 201 7.1E-26 T 12-10-2018 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 588 600 7.1E-26 T 12-10-2018 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 522 7.1E-26 T 12-10-2018 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 338 352 7.1E-26 T 12-10-2018 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 584 7.1E-26 T 12-10-2018 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 537 553 9.1E-6 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 565 581 9.1E-6 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 Gene3D G3DSA:3.40.50.1000 496 617 2.4E-25 T 12-10-2018 IPR023214 HAD superfamily TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 340 346 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 486 650 1.4E-38 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 151 373 8.9E-29 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TL08_22360 b6f1cbecad75ea3914bf16792345da3f 732 Gene3D G3DSA:3.40.1110.10 349 495 3.0E-39 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TL08_20630 ba9767600a7fc254621586d495c580f9 627 SUPERFAMILY SSF56601 280 620 4.05E-65 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_20630 ba9767600a7fc254621586d495c580f9 627 Gene3D G3DSA:3.90.1310.30 138 320 2.1E-17 T 12-10-2018 TL08_20630 ba9767600a7fc254621586d495c580f9 627 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 31 137 6.4E-10 T 12-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 TL08_20630 ba9767600a7fc254621586d495c580f9 627 Gene3D G3DSA:3.40.710.10 321 626 4.7E-66 T 12-10-2018 TL08_20630 ba9767600a7fc254621586d495c580f9 627 Pfam PF00905 Penicillin binding protein transpeptidase domain 346 615 8.9E-44 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TL08_20630 ba9767600a7fc254621586d495c580f9 627 SUPERFAMILY SSF56519 138 324 3.92E-25 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TL08_20630 ba9767600a7fc254621586d495c580f9 627 Pfam PF03717 Penicillin-binding Protein dimerisation domain 146 301 1.2E-16 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TL08_04775 d95857b734d56f29dbfcdc3ee3f07fd3 213 SUPERFAMILY SSF48498 93 205 4.8E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_04775 d95857b734d56f29dbfcdc3ee3f07fd3 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.8E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_04775 d95857b734d56f29dbfcdc3ee3f07fd3 213 SUPERFAMILY SSF46689 15 94 2.24E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_04775 d95857b734d56f29dbfcdc3ee3f07fd3 213 Gene3D G3DSA:1.10.357.10 11 211 6.1E-48 T 12-10-2018 TL08_04775 d95857b734d56f29dbfcdc3ee3f07fd3 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 7.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_04775 d95857b734d56f29dbfcdc3ee3f07fd3 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 7.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_22080 7c323e167627a1962f770e7d8c796983 380 SMART SM00855 177 335 6.4E-19 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_22080 7c323e167627a1962f770e7d8c796983 380 SUPERFAMILY SSF53254 175 379 5.76E-51 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_22080 7c323e167627a1962f770e7d8c796983 380 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 178 374 4.4E-54 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_22080 7c323e167627a1962f770e7d8c796983 380 Pfam PF13456 Reverse transcriptase-like 10 132 1.2E-24 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 TL08_22080 7c323e167627a1962f770e7d8c796983 380 Gene3D G3DSA:3.40.50.1240 176 380 1.9E-51 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_22080 7c323e167627a1962f770e7d8c796983 380 PIRSF PIRSF036922 2 380 8.9E-160 T 12-10-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing TL08_22080 7c323e167627a1962f770e7d8c796983 380 Gene3D G3DSA:3.30.420.10 6 142 1.2E-40 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_22080 7c323e167627a1962f770e7d8c796983 380 SUPERFAMILY SSF53098 7 131 6.96E-29 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_22950 e97fc6c214f779aeb68f7154978f0551 138 Gene3D G3DSA:3.30.70.120 26 135 1.9E-36 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TL08_22950 e97fc6c214f779aeb68f7154978f0551 138 Pfam PF03091 CutA1 divalent ion tolerance protein 37 133 4.2E-34 T 12-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TL08_22950 e97fc6c214f779aeb68f7154978f0551 138 SUPERFAMILY SSF54913 35 135 6.67E-35 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TL08_21880 79f2642bdbd02407ce665d5fc7660721 258 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 89 141 2.0E-17 T 12-10-2018 TL08_21880 79f2642bdbd02407ce665d5fc7660721 258 Pfam PF03099 Biotin/lipoate A/B protein ligase family 74 178 1.7E-8 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TL08_21880 79f2642bdbd02407ce665d5fc7660721 258 PIRSF PIRSF016262 16 237 1.8E-60 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TL08_21880 79f2642bdbd02407ce665d5fc7660721 258 Gene3D G3DSA:3.30.930.10 14 224 8.7E-79 T 12-10-2018 TL08_21880 79f2642bdbd02407ce665d5fc7660721 258 SUPERFAMILY SSF55681 17 224 2.32E-66 T 12-10-2018 TL08_21880 79f2642bdbd02407ce665d5fc7660721 258 Hamap MF_00013 Octanoyltransferase [lipB]. 19 226 33.879 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TL08_21880 79f2642bdbd02407ce665d5fc7660721 258 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 43 201 1.5E-39 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TL08_21880 79f2642bdbd02407ce665d5fc7660721 258 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 85 100 - T 12-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TL08_03725 50af5f629ec85eb6b76b993925a0e714 188 Pfam PF14124 Domain of unknown function (DUF4291) 5 182 5.0E-68 T 12-10-2018 IPR025633 Protein of unknown function DUF4291 TL08_24635 8c2d9b168e2fc4ea2773e7085881bd59 228 Pfam PF12840 Helix-turn-helix domain 14 71 1.6E-13 T 12-10-2018 TL08_24635 8c2d9b168e2fc4ea2773e7085881bd59 228 SUPERFAMILY SSF46785 12 131 5.47E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_24635 8c2d9b168e2fc4ea2773e7085881bd59 228 Gene3D G3DSA:1.10.10.10 12 121 1.9E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_24635 8c2d9b168e2fc4ea2773e7085881bd59 228 SMART SM00418 13 96 8.4E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 SMART SM00959 1 39 1.5E-6 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 Gene3D G3DSA:2.40.50.140 193 332 4.0E-30 T 12-10-2018 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 TIGRFAM TIGR00767 rho: transcription termination factor Rho 1 617 2.6E-190 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 Pfam PF07497 Rho termination factor, RNA-binding domain 253 328 9.0E-29 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 Hamap MF_01884 Transcription termination factor Rho [rho]. 246 619 190.053 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 Pfam PF07498 Rho termination factor, N-terminal domain 1 34 4.9E-10 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 Gene3D G3DSA:3.40.50.300 333 622 1.1E-116 T 12-10-2018 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 359 563 3.6E-21 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 SMART SM00357 254 321 1.1E-6 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 SUPERFAMILY SSF52540 290 571 1.81E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07255 ca471d112a262bcd99b1c7d7b8a9fbc6 626 SMART SM00382 370 555 1.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_16530 93b1e176035d273b32e6e679212beb8e 687 SUPERFAMILY SSF46767 576 632 6.15E-6 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TL08_16530 93b1e176035d273b32e6e679212beb8e 687 Gene3D G3DSA:1.10.10.10 574 669 3.5E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16530 93b1e176035d273b32e6e679212beb8e 687 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 577 630 1.7E-5 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TL08_16530 93b1e176035d273b32e6e679212beb8e 687 Pfam PF03235 Protein of unknown function DUF262 8 224 3.4E-36 T 12-10-2018 IPR004919 Domain of unknown function DUF262 TL08_16530 93b1e176035d273b32e6e679212beb8e 687 Pfam PF07510 Protein of unknown function (DUF1524) 409 551 8.8E-24 T 12-10-2018 IPR011089 Domain of unknown function DUF1524 TL08_26035 2359bb27a897876bf6ebb0e2ec9ab1e3 276 Gene3D G3DSA:3.40.50.150 2 276 9.3E-91 T 12-10-2018 TL08_26035 2359bb27a897876bf6ebb0e2ec9ab1e3 276 Pfam PF04672 S-adenosyl methyltransferase 7 251 4.3E-77 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_26035 2359bb27a897876bf6ebb0e2ec9ab1e3 276 PIRSF PIRSF017393 2 275 2.9E-83 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_26035 2359bb27a897876bf6ebb0e2ec9ab1e3 276 SUPERFAMILY SSF53335 17 242 6.76E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_02940 b6520c80746675ff3bd083e54f03f265 201 SUPERFAMILY SSF52172 2 129 1.31E-28 T 12-10-2018 IPR011006 CheY-like superfamily TL08_02940 b6520c80746675ff3bd083e54f03f265 201 SMART SM00421 138 195 1.7E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02940 b6520c80746675ff3bd083e54f03f265 201 SUPERFAMILY SSF46894 130 201 1.53E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_02940 b6520c80746675ff3bd083e54f03f265 201 Gene3D G3DSA:3.40.50.12740 2 201 7.9E-53 T 12-10-2018 TL08_02940 b6520c80746675ff3bd083e54f03f265 201 Pfam PF00072 Response regulator receiver domain 4 116 1.4E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_02940 b6520c80746675ff3bd083e54f03f265 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 5.2E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02940 b6520c80746675ff3bd083e54f03f265 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 5.2E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02940 b6520c80746675ff3bd083e54f03f265 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 5.2E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02940 b6520c80746675ff3bd083e54f03f265 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 2.4E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02940 b6520c80746675ff3bd083e54f03f265 201 SMART SM00448 2 115 6.8E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_19215 9211a67fec88040747c39389d8676e91 284 SUPERFAMILY SSF53474 9 279 2.72E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_19215 9211a67fec88040747c39389d8676e91 284 Pfam PF00756 Putative esterase 22 205 4.0E-15 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TL08_19215 9211a67fec88040747c39389d8676e91 284 Gene3D G3DSA:3.40.50.1820 8 283 4.7E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_03200 3987cd750643575081b837b65a0e3d04 511 Pfam PF00990 Diguanylate cyclase, GGDEF domain 327 489 8.6E-37 T 12-10-2018 IPR000160 GGDEF domain TL08_03200 3987cd750643575081b837b65a0e3d04 511 SUPERFAMILY SSF55073 332 492 9.42E-40 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_03200 3987cd750643575081b837b65a0e3d04 511 SMART SM00267 316 493 1.2E-41 T 12-10-2018 IPR000160 GGDEF domain TL08_03200 3987cd750643575081b837b65a0e3d04 511 SUPERFAMILY SSF48452 161 261 1.37E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03200 3987cd750643575081b837b65a0e3d04 511 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 325 493 1.6E-39 T 12-10-2018 IPR000160 GGDEF domain TL08_03200 3987cd750643575081b837b65a0e3d04 511 SUPERFAMILY SSF48452 22 133 9.7E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03200 3987cd750643575081b837b65a0e3d04 511 Gene3D G3DSA:1.25.40.10 18 325 4.2E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_03200 3987cd750643575081b837b65a0e3d04 511 Gene3D G3DSA:3.30.70.270 326 498 3.0E-48 T 12-10-2018 TL08_19645 c4043a5968cffa79d366f33a5ddb316f 493 Gene3D G3DSA:2.60.40.420 18 166 5.7E-47 T 12-10-2018 IPR008972 Cupredoxin TL08_19645 c4043a5968cffa79d366f33a5ddb316f 493 Pfam PF07732 Multicopper oxidase 58 170 1.7E-33 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TL08_19645 c4043a5968cffa79d366f33a5ddb316f 493 Gene3D G3DSA:2.60.40.420 352 480 4.3E-38 T 12-10-2018 IPR008972 Cupredoxin TL08_19645 c4043a5968cffa79d366f33a5ddb316f 493 SUPERFAMILY SSF49503 31 170 9.13E-37 T 12-10-2018 IPR008972 Cupredoxin TL08_19645 c4043a5968cffa79d366f33a5ddb316f 493 SUPERFAMILY SSF49503 175 294 2.41E-25 T 12-10-2018 IPR008972 Cupredoxin TL08_19645 c4043a5968cffa79d366f33a5ddb316f 493 Pfam PF07731 Multicopper oxidase 361 473 9.1E-22 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 TL08_19645 c4043a5968cffa79d366f33a5ddb316f 493 Gene3D G3DSA:2.60.40.420 168 348 1.4E-43 T 12-10-2018 IPR008972 Cupredoxin TL08_19645 c4043a5968cffa79d366f33a5ddb316f 493 SUPERFAMILY SSF49503 365 473 2.79E-28 T 12-10-2018 IPR008972 Cupredoxin TL08_19645 c4043a5968cffa79d366f33a5ddb316f 493 ProSitePatterns PS00080 Multicopper oxidases signature 2. 456 467 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 TL08_19915 90458f55822e953fbbbec4ddfc390814 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_19915 90458f55822e953fbbbec4ddfc390814 329 SUPERFAMILY SSF50129 1 171 2.74E-54 T 12-10-2018 IPR011032 GroES-like superfamily TL08_19915 90458f55822e953fbbbec4ddfc390814 329 Gene3D G3DSA:3.90.180.10 14 310 1.8E-96 T 12-10-2018 TL08_19915 90458f55822e953fbbbec4ddfc390814 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 1.1E-33 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_19915 90458f55822e953fbbbec4ddfc390814 329 Pfam PF00107 Zinc-binding dehydrogenase 173 291 3.1E-16 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_19915 90458f55822e953fbbbec4ddfc390814 329 SUPERFAMILY SSF51735 136 317 3.52E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19915 90458f55822e953fbbbec4ddfc390814 329 SMART SM00829 10 327 9.2E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_19915 90458f55822e953fbbbec4ddfc390814 329 Gene3D G3DSA:3.40.50.720 150 276 1.8E-96 T 12-10-2018 TL08_04345 5d0a2e00e2e79d15175572f38375f694 294 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_04345 5d0a2e00e2e79d15175572f38375f694 294 SUPERFAMILY SSF52540 15 231 1.24E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04345 5d0a2e00e2e79d15175572f38375f694 294 Gene3D G3DSA:3.40.50.300 13 290 4.0E-65 T 12-10-2018 TL08_04345 5d0a2e00e2e79d15175572f38375f694 294 SMART SM00382 42 228 8.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_04345 5d0a2e00e2e79d15175572f38375f694 294 Pfam PF00005 ABC transporter 33 179 2.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_18530 db6dcb2fdad5ff5436d2fb8ab98817e3 207 Gene3D G3DSA:1.20.58.480 1 131 5.9E-31 T 12-10-2018 TL08_18530 db6dcb2fdad5ff5436d2fb8ab98817e3 207 Pfam PF03301 Tryptophan 2,3-dioxygenase 3 127 2.1E-18 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 TL08_18530 db6dcb2fdad5ff5436d2fb8ab98817e3 207 SUPERFAMILY SSF140959 5 181 1.57E-33 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 TL08_18530 db6dcb2fdad5ff5436d2fb8ab98817e3 207 Gene3D G3DSA:1.20.58.480 132 187 6.2E-7 T 12-10-2018 TL08_18760 4411e6eecb10c75de101cee153d9ca19 72 SMART SM00704 25 65 1.0E-8 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TL08_18760 4411e6eecb10c75de101cee153d9ca19 72 Pfam PF09360 Iron-binding zinc finger CDGSH type 15 60 1.4E-19 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TL08_18760 4411e6eecb10c75de101cee153d9ca19 72 Gene3D G3DSA:3.40.5.90 7 71 6.2E-17 T 12-10-2018 TL08_23210 d5b167d3163eacb08077080ed78afb31 446 Gene3D G3DSA:3.65.10.10 22 422 6.3E-141 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TL08_23210 d5b167d3163eacb08077080ed78afb31 446 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 19 423 1.3E-112 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TL08_23210 d5b167d3163eacb08077080ed78afb31 446 SUPERFAMILY SSF55205 18 428 4.09E-106 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TL08_23210 d5b167d3163eacb08077080ed78afb31 446 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 18 432 29.098 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TL08_23210 d5b167d3163eacb08077080ed78afb31 446 ProSitePatterns PS00885 EPSP synthase signature 2. 345 363 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TL08_23210 d5b167d3163eacb08077080ed78afb31 446 Gene3D G3DSA:3.65.10.10 30 250 6.3E-141 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TL08_23210 d5b167d3163eacb08077080ed78afb31 446 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 23 429 3.7E-114 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TL08_23210 d5b167d3163eacb08077080ed78afb31 446 ProSitePatterns PS00104 EPSP synthase signature 1. 99 113 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TL08_23210 d5b167d3163eacb08077080ed78afb31 446 PIRSF PIRSF000505 8 434 2.0E-117 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TL08_21155 a958d7ba49a33fca1d8385fd91cf0b2d 572 SUPERFAMILY SSF53474 51 392 3.87E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21155 a958d7ba49a33fca1d8385fd91cf0b2d 572 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 72 416 2.0E-81 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 TL08_21155 a958d7ba49a33fca1d8385fd91cf0b2d 572 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 68 335 7.4E-51 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TL08_21155 a958d7ba49a33fca1d8385fd91cf0b2d 572 SMART SM00939 358 529 1.5E-7 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 TL08_21155 a958d7ba49a33fca1d8385fd91cf0b2d 572 SUPERFAMILY SSF49785 358 503 6.16E-10 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_21155 a958d7ba49a33fca1d8385fd91cf0b2d 572 Gene3D G3DSA:3.40.50.1820 27 264 4.8E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21155 a958d7ba49a33fca1d8385fd91cf0b2d 572 Gene3D G3DSA:3.40.50.1820 273 423 5.3E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_12445 721f2917a7e4b6c574e1dc58659ea105 362 Pfam PF00107 Zinc-binding dehydrogenase 190 315 2.0E-14 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_12445 721f2917a7e4b6c574e1dc58659ea105 362 Gene3D G3DSA:3.90.180.10 25 344 3.6E-75 T 12-10-2018 TL08_12445 721f2917a7e4b6c574e1dc58659ea105 362 SUPERFAMILY SSF50129 7 187 5.66E-43 T 12-10-2018 IPR011032 GroES-like superfamily TL08_12445 721f2917a7e4b6c574e1dc58659ea105 362 SMART SM00829 17 353 3.1E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_12445 721f2917a7e4b6c574e1dc58659ea105 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 148 6.6E-26 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_12445 721f2917a7e4b6c574e1dc58659ea105 362 Gene3D G3DSA:3.40.50.720 168 301 3.6E-75 T 12-10-2018 TL08_12445 721f2917a7e4b6c574e1dc58659ea105 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 74 88 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_12445 721f2917a7e4b6c574e1dc58659ea105 362 SUPERFAMILY SSF51735 153 315 3.09E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_03465 a78d28d270fffafbf95ee2b42933327d 432 Pfam PF09967 VWA-like domain (DUF2201) 304 425 2.0E-19 T 12-10-2018 IPR018698 VWA-like domain TL08_03465 a78d28d270fffafbf95ee2b42933327d 432 Pfam PF13203 Putative metallopeptidase domain 79 293 6.7E-22 T 12-10-2018 IPR025154 Putative metallopeptidase domain TL08_03465 a78d28d270fffafbf95ee2b42933327d 432 Gene3D G3DSA:3.40.50.410 301 420 1.9E-5 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_03465 a78d28d270fffafbf95ee2b42933327d 432 SUPERFAMILY SSF53300 302 417 6.16E-11 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_09260 98be9486efc9e7facaa2dc93e9109d74 114 Gene3D G3DSA:2.102.10.10 4 112 8.0E-38 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_09260 98be9486efc9e7facaa2dc93e9109d74 114 SUPERFAMILY SSF50022 7 113 2.49E-34 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_09260 98be9486efc9e7facaa2dc93e9109d74 114 Pfam PF13806 Rieske-like [2Fe-2S] domain 8 111 6.2E-34 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 TL08_09260 98be9486efc9e7facaa2dc93e9109d74 114 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 8 111 1.1E-34 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 TL08_00900 fc1b02ce032c758cd7fede47594667ce 521 Gene3D G3DSA:3.40.190.10 190 504 2.1E-81 T 12-10-2018 TL08_00900 fc1b02ce032c758cd7fede47594667ce 521 Gene3D G3DSA:3.90.76.10 50 189 2.1E-81 T 12-10-2018 TL08_00900 fc1b02ce032c758cd7fede47594667ce 521 SUPERFAMILY SSF53850 35 518 1.76E-92 T 12-10-2018 TL08_00900 fc1b02ce032c758cd7fede47594667ce 521 PIRSF PIRSF002741 1 519 2.6E-59 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_00900 fc1b02ce032c758cd7fede47594667ce 521 Gene3D G3DSA:3.10.105.10 265 494 2.1E-81 T 12-10-2018 TL08_00900 fc1b02ce032c758cd7fede47594667ce 521 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 431 7.7E-58 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_10750 74459985678fb064b4f3a35e61352695 242 SUPERFAMILY SSF46955 27 84 1.14E-11 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_10750 74459985678fb064b4f3a35e61352695 242 Pfam PF13411 MerR HTH family regulatory protein 28 81 3.6E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_10750 74459985678fb064b4f3a35e61352695 242 Gene3D G3DSA:1.10.1660.10 27 232 2.0E-17 T 12-10-2018 TL08_10750 74459985678fb064b4f3a35e61352695 242 SMART SM00422 12 86 3.1E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_23595 88d0105fb558d15a468222165ddde95c 318 SUPERFAMILY SSF51569 21 310 1.65E-68 T 12-10-2018 TL08_23595 88d0105fb558d15a468222165ddde95c 318 Gene3D G3DSA:3.20.20.70 19 317 2.2E-123 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_23595 88d0105fb558d15a468222165ddde95c 318 Pfam PF00682 HMGL-like 25 296 2.0E-47 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TL08_21395 14bd314b0ebbc4558337cc3fc04ad86d 254 SUPERFAMILY SSF75217 82 254 6.8E-42 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TL08_21395 14bd314b0ebbc4558337cc3fc04ad86d 254 Gene3D G3DSA:3.40.1280.10 83 254 1.2E-51 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TL08_21395 14bd314b0ebbc4558337cc3fc04ad86d 254 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 18 249 1.6E-38 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TL08_21395 14bd314b0ebbc4558337cc3fc04ad86d 254 SUPERFAMILY SSF88697 21 79 6.96E-11 T 12-10-2018 IPR015947 PUA-like superfamily TL08_21395 14bd314b0ebbc4558337cc3fc04ad86d 254 Gene3D G3DSA:2.40.240.20 14 81 5.3E-19 T 12-10-2018 TL08_21395 14bd314b0ebbc4558337cc3fc04ad86d 254 Pfam PF04452 RNA methyltransferase 28 248 1.3E-59 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TL08_21395 14bd314b0ebbc4558337cc3fc04ad86d 254 PIRSF PIRSF015601 15 254 1.6E-51 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TL08_10310 49ad500eb2910f35d9b1f40fb56498e8 199 SUPERFAMILY SSF55729 4 175 1.52E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_10310 49ad500eb2910f35d9b1f40fb56498e8 199 Pfam PF00583 Acetyltransferase (GNAT) family 41 149 1.1E-10 T 12-10-2018 IPR000182 GNAT domain TL08_10310 49ad500eb2910f35d9b1f40fb56498e8 199 Gene3D G3DSA:3.40.630.30 4 179 8.3E-37 T 12-10-2018 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 342 349 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 Gene3D G3DSA:3.40.630.10 163 497 1.5E-127 T 12-10-2018 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 Gene3D G3DSA:3.40.220.10 5 157 7.2E-25 T 12-10-2018 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 6 496 33.914 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 PRINTS PR00481 Cytosol aminopeptidase signature 316 337 3.7E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 PRINTS PR00481 Cytosol aminopeptidase signature 366 381 3.7E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 PRINTS PR00481 Cytosol aminopeptidase signature 257 274 3.7E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 PRINTS PR00481 Cytosol aminopeptidase signature 279 300 3.7E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 PRINTS PR00481 Cytosol aminopeptidase signature 338 358 3.7E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 SUPERFAMILY SSF52949 19 149 6.47E-21 T 12-10-2018 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 SUPERFAMILY SSF53187 176 494 5.96E-108 T 12-10-2018 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 30 145 2.0E-18 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TL08_21855 b9fb2fb0c7cefa65d4a4658dd8384f2b 498 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 182 487 6.8E-116 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TL08_04665 156798ecc7ff30964b929b35258a1818 384 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 120 365 5.9E-87 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TL08_04665 156798ecc7ff30964b929b35258a1818 384 Gene3D G3DSA:3.40.50.300 115 364 6.9E-68 T 12-10-2018 TL08_04665 156798ecc7ff30964b929b35258a1818 384 SUPERFAMILY SSF117916 12 101 2.68E-23 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TL08_04665 156798ecc7ff30964b929b35258a1818 384 SUPERFAMILY SSF52540 120 365 2.13E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04665 156798ecc7ff30964b929b35258a1818 384 Hamap MF_02040 Iron-sulfur cluster carrier protein. 111 366 33.194 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TL08_04665 156798ecc7ff30964b929b35258a1818 384 Pfam PF01883 Iron-sulfur cluster assembly protein 15 85 1.4E-19 T 12-10-2018 IPR002744 MIP18 family-like TL08_04665 156798ecc7ff30964b929b35258a1818 384 Gene3D G3DSA:3.30.300.130 8 107 5.6E-22 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TL08_04665 156798ecc7ff30964b929b35258a1818 384 ProSitePatterns PS01215 Mrp family signature. 224 240 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 TL08_11920 e4947d17b68ffd1ac93f9e5646b36a21 227 Gene3D G3DSA:2.60.120.560 42 224 1.9E-45 T 12-10-2018 TL08_11920 e4947d17b68ffd1ac93f9e5646b36a21 227 Pfam PF06439 Domain of Unknown Function (DUF1080) 50 221 1.1E-44 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 TL08_10490 7e0690a5a820d9d51ac33da33bf1a2fc 111 Gene3D G3DSA:3.30.70.100 3 106 1.4E-11 T 12-10-2018 TL08_10490 7e0690a5a820d9d51ac33da33bf1a2fc 111 SUPERFAMILY SSF54909 1 94 1.16E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_10490 7e0690a5a820d9d51ac33da33bf1a2fc 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 73 2.5E-6 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TL08_27150 e67a0dc30a53c46600f6ea3301536f23 107 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 12 83 5.0E-12 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TL08_27150 e67a0dc30a53c46600f6ea3301536f23 107 Gene3D G3DSA:3.30.230.10 4 89 9.1E-16 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_27150 e67a0dc30a53c46600f6ea3301536f23 107 Pfam PF00825 Ribonuclease P 14 82 3.7E-18 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TL08_27150 e67a0dc30a53c46600f6ea3301536f23 107 SUPERFAMILY SSF54211 11 84 3.29E-16 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_17005 a70b410add5017ea6554a63b97bf63df 771 Pfam PF00005 ABC transporter 481 684 8.0E-12 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_17005 a70b410add5017ea6554a63b97bf63df 771 SMART SM00382 38 427 3.5 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17005 a70b410add5017ea6554a63b97bf63df 771 SMART SM00382 490 723 0.058 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17005 a70b410add5017ea6554a63b97bf63df 771 SUPERFAMILY SSF52540 16 439 1.14E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17005 a70b410add5017ea6554a63b97bf63df 771 ProSitePatterns PS00211 ABC transporters family signature. 657 671 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_17005 a70b410add5017ea6554a63b97bf63df 771 Gene3D G3DSA:1.20.1580.10 106 350 1.3E-160 T 12-10-2018 TL08_17005 a70b410add5017ea6554a63b97bf63df 771 Gene3D G3DSA:3.40.50.300 476 760 9.8E-105 T 12-10-2018 TL08_17005 a70b410add5017ea6554a63b97bf63df 771 Gene3D G3DSA:1.20.1580.10 558 596 9.8E-105 T 12-10-2018 TL08_17005 a70b410add5017ea6554a63b97bf63df 771 Gene3D G3DSA:1.10.8.280 160 272 1.3E-160 T 12-10-2018 TL08_17005 a70b410add5017ea6554a63b97bf63df 771 SUPERFAMILY SSF52540 477 737 2.39E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17005 a70b410add5017ea6554a63b97bf63df 771 Gene3D G3DSA:3.40.50.300 20 450 1.3E-160 T 12-10-2018 TL08_23905 64abaa22f6e6f2af6f43004c5865e954 519 Pfam PF00005 ABC transporter 292 445 2.0E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23905 64abaa22f6e6f2af6f43004c5865e954 519 Gene3D G3DSA:3.40.50.300 8 254 7.0E-55 T 12-10-2018 TL08_23905 64abaa22f6e6f2af6f43004c5865e954 519 SUPERFAMILY SSF52540 22 241 5.72E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23905 64abaa22f6e6f2af6f43004c5865e954 519 Gene3D G3DSA:3.40.50.300 281 514 2.7E-45 T 12-10-2018 TL08_23905 64abaa22f6e6f2af6f43004c5865e954 519 ProSitePatterns PS00211 ABC transporters family signature. 418 432 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_23905 64abaa22f6e6f2af6f43004c5865e954 519 SMART SM00382 48 236 1.0E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23905 64abaa22f6e6f2af6f43004c5865e954 519 SMART SM00382 300 494 3.4E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23905 64abaa22f6e6f2af6f43004c5865e954 519 Pfam PF00005 ABC transporter 39 189 2.6E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23905 64abaa22f6e6f2af6f43004c5865e954 519 SUPERFAMILY SSF52540 280 506 2.15E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19845 bde75b670a29d9d98873dcaf8352a3b3 204 Pfam PF07336 Putative stress-induced transcription regulator 6 150 7.7E-16 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator TL08_19845 bde75b670a29d9d98873dcaf8352a3b3 204 Gene3D G3DSA:1.10.3300.10 2 195 1.3E-20 T 12-10-2018 IPR023286 ABATE domain superfamily TL08_19845 bde75b670a29d9d98873dcaf8352a3b3 204 SUPERFAMILY SSF160904 2 193 1.7E-35 T 12-10-2018 TL08_19845 bde75b670a29d9d98873dcaf8352a3b3 204 Pfam PF11706 CGNR zinc finger 154 194 1.7E-8 T 12-10-2018 IPR021005 Zinc finger, CGNR TL08_24705 5bac7e8ae0aa748fdb6c542f7256f6df 379 Gene3D G3DSA:1.10.260.40 102 171 1.5E-12 T 12-10-2018 TL08_24705 5bac7e8ae0aa748fdb6c542f7256f6df 379 SMART SM00530 112 167 6.8E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_24705 5bac7e8ae0aa748fdb6c542f7256f6df 379 Pfam PF13560 Helix-turn-helix domain 109 167 3.4E-13 T 12-10-2018 TL08_24705 5bac7e8ae0aa748fdb6c542f7256f6df 379 SUPERFAMILY SSF47413 103 163 1.48E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_26285 9e0ecf17f00edf408c353ecf566c7118 345 SUPERFAMILY SSF52540 2 225 4.62E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26285 9e0ecf17f00edf408c353ecf566c7118 345 Gene3D G3DSA:3.40.50.300 1 227 3.9E-56 T 12-10-2018 TL08_26285 9e0ecf17f00edf408c353ecf566c7118 345 Pfam PF00005 ABC transporter 18 156 2.4E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_26285 9e0ecf17f00edf408c353ecf566c7118 345 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_26285 9e0ecf17f00edf408c353ecf566c7118 345 SMART SM00382 26 204 7.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_04475 a85171be6da0565d04fb7b750c418d0f 340 Gene3D G3DSA:3.40.718.10 1 330 7.7E-111 T 12-10-2018 TL08_04475 a85171be6da0565d04fb7b750c418d0f 340 SUPERFAMILY SSF53659 4 328 1.17E-96 T 12-10-2018 TL08_04475 a85171be6da0565d04fb7b750c418d0f 340 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 7 327 7.0E-92 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TL08_04475 a85171be6da0565d04fb7b750c418d0f 340 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 38 322 5.7E-86 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TL08_01565 fa395ed656ef40556235b718e0cc9049 247 SUPERFAMILY SSF47413 2 61 5.63E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_03370 2ea6426c97bc52474e82d3983d142a55 348 Gene3D G3DSA:3.40.710.10 16 330 5.9E-77 T 12-10-2018 TL08_03370 2ea6426c97bc52474e82d3983d142a55 348 Pfam PF00144 Beta-lactamase 32 322 1.1E-55 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_03370 2ea6426c97bc52474e82d3983d142a55 348 SUPERFAMILY SSF56601 32 321 7.0E-71 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_22895 eef286026a269fca16387762534f6166 253 SUPERFAMILY SSF53474 7 250 7.19E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_22895 eef286026a269fca16387762534f6166 253 Pfam PF00561 alpha/beta hydrolase fold 16 139 6.0E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_22895 eef286026a269fca16387762534f6166 253 Gene3D G3DSA:3.40.50.1820 3 251 2.4E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07620 be69fb9ddbe32785ce42a068ed4d9b32 108 Gene3D G3DSA:1.10.10.10 1 101 2.0E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07620 be69fb9ddbe32785ce42a068ed4d9b32 108 SMART SM00418 2 83 2.5E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_07620 be69fb9ddbe32785ce42a068ed4d9b32 108 Pfam PF12840 Helix-turn-helix domain 2 60 2.4E-14 T 12-10-2018 TL08_07620 be69fb9ddbe32785ce42a068ed4d9b32 108 SUPERFAMILY SSF46785 2 92 4.77E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_13100 3c21d99bfd57824b5244c3dadf2e906e 93 SUPERFAMILY SSF50249 24 92 1.62E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_13100 3c21d99bfd57824b5244c3dadf2e906e 93 PIRSF PIRSF002599 23 93 2.7E-25 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 TL08_13100 3c21d99bfd57824b5244c3dadf2e906e 93 PRINTS PR00050 Cold shock protein signature 30 45 8.3E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_13100 3c21d99bfd57824b5244c3dadf2e906e 93 PRINTS PR00050 Cold shock protein signature 50 59 8.3E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_13100 3c21d99bfd57824b5244c3dadf2e906e 93 PRINTS PR00050 Cold shock protein signature 65 83 8.3E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_13100 3c21d99bfd57824b5244c3dadf2e906e 93 Pfam PF00313 'Cold-shock' DNA-binding domain 29 90 2.6E-29 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TL08_13100 3c21d99bfd57824b5244c3dadf2e906e 93 ProSitePatterns PS00352 'Cold-shock' domain signature. 41 59 - T 12-10-2018 IPR019844 Cold-shock conserved site TL08_13100 3c21d99bfd57824b5244c3dadf2e906e 93 Gene3D G3DSA:2.40.50.140 27 90 2.3E-31 T 12-10-2018 TL08_13100 3c21d99bfd57824b5244c3dadf2e906e 93 SMART SM00357 29 92 1.6E-30 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 TL08_09440 d9a53db801c5011ceca5dd3cce4a114f 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 136 8.7E-37 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TL08_09440 d9a53db801c5011ceca5dd3cce4a114f 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 2.6E-19 T 12-10-2018 IPR020603 MraZ domain TL08_09440 d9a53db801c5011ceca5dd3cce4a114f 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 134 9.8E-19 T 12-10-2018 IPR020603 MraZ domain TL08_09440 d9a53db801c5011ceca5dd3cce4a114f 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 123 3.0E-46 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TL08_09440 d9a53db801c5011ceca5dd3cce4a114f 143 SUPERFAMILY SSF89447 1 135 8.97E-46 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily TL08_09440 d9a53db801c5011ceca5dd3cce4a114f 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 51.099 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TL08_09440 d9a53db801c5011ceca5dd3cce4a114f 143 Gene3D G3DSA:2.40.330.20 1 139 1.6E-44 T 12-10-2018 IPR038619 MraZ superfamily TL08_20700 bffbdc11bba023da7f0564ef50804665 548 Pfam PF04616 Glycosyl hydrolases family 43 28 301 6.0E-67 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 TL08_20700 bffbdc11bba023da7f0564ef50804665 548 SUPERFAMILY SSF49899 336 519 1.46E-21 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TL08_20700 bffbdc11bba023da7f0564ef50804665 548 SUPERFAMILY SSF75005 28 306 1.96E-72 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_20700 bffbdc11bba023da7f0564ef50804665 548 Gene3D G3DSA:2.115.10.20 24 312 9.2E-70 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_20700 bffbdc11bba023da7f0564ef50804665 548 Gene3D G3DSA:2.60.120.200 334 537 2.4E-33 T 12-10-2018 TL08_05630 e2868c0a2effabb02ae9ad247f50af1e 201 SUPERFAMILY SSF51182 1 197 2.91E-60 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_05630 e2868c0a2effabb02ae9ad247f50af1e 201 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 8.0E-63 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TL08_05630 e2868c0a2effabb02ae9ad247f50af1e 201 Gene3D G3DSA:2.60.120.10 1 200 9.6E-61 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_05630 e2868c0a2effabb02ae9ad247f50af1e 201 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 3.0E-49 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TL08_19625 c7272ce3a607bc91a6c8602cc19b60c5 455 Pfam PF13560 Helix-turn-helix domain 23 79 6.8E-8 T 12-10-2018 TL08_19625 c7272ce3a607bc91a6c8602cc19b60c5 455 SUPERFAMILY SSF47413 24 89 5.09E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_19625 c7272ce3a607bc91a6c8602cc19b60c5 455 SMART SM00530 27 83 6.7E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_19625 c7272ce3a607bc91a6c8602cc19b60c5 455 Gene3D G3DSA:1.10.260.40 17 86 1.6E-10 T 12-10-2018 TL08_03755 0ad6905940f71ca54b863042be2d56e3 295 Pfam PF13406 Transglycosylase SLT domain 207 254 2.0E-7 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 TL08_03755 0ad6905940f71ca54b863042be2d56e3 295 SUPERFAMILY SSF53955 123 289 6.3E-35 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_03755 0ad6905940f71ca54b863042be2d56e3 295 Gene3D G3DSA:1.10.530.10 109 293 2.3E-6 T 12-10-2018 TL08_02455 a7c22fbc842bdcf45937e6a75b28e26d 597 Pfam PF05140 ResB-like family 26 512 3.0E-126 T 12-10-2018 IPR007816 ResB-like domain TL08_17995 6af45baee9467208b1e359cb49063de1 231 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17995 6af45baee9467208b1e359cb49063de1 231 Pfam PF00072 Response regulator receiver domain 4 125 1.3E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_17995 6af45baee9467208b1e359cb49063de1 231 SUPERFAMILY SSF52172 1 198 4.33E-29 T 12-10-2018 IPR011006 CheY-like superfamily TL08_17995 6af45baee9467208b1e359cb49063de1 231 Gene3D G3DSA:3.40.50.12740 2 227 2.3E-65 T 12-10-2018 TL08_17995 6af45baee9467208b1e359cb49063de1 231 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 220 7.1E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17995 6af45baee9467208b1e359cb49063de1 231 SMART SM00448 2 125 5.2E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_17995 6af45baee9467208b1e359cb49063de1 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 2.6E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17995 6af45baee9467208b1e359cb49063de1 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 2.6E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17995 6af45baee9467208b1e359cb49063de1 231 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 2.6E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_17995 6af45baee9467208b1e359cb49063de1 231 SMART SM00421 164 221 1.3E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_00610 9b934dcaa4401f556e36cd50f23c40e7 208 Gene3D G3DSA:3.40.50.1240 4 204 1.9E-39 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_00610 9b934dcaa4401f556e36cd50f23c40e7 208 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 TL08_00610 9b934dcaa4401f556e36cd50f23c40e7 208 PIRSF PIRSF000709 4 177 8.1E-9 T 12-10-2018 TL08_00610 9b934dcaa4401f556e36cd50f23c40e7 208 SUPERFAMILY SSF53254 5 197 5.89E-41 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_00610 9b934dcaa4401f556e36cd50f23c40e7 208 SMART SM00855 5 160 6.7E-15 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_00610 9b934dcaa4401f556e36cd50f23c40e7 208 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 201 1.0E-43 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_22310 d39de3631a5925185392e4b2b760ae06 292 SUPERFAMILY SSF47413 13 71 2.5E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_22310 d39de3631a5925185392e4b2b760ae06 292 Pfam PF13560 Helix-turn-helix domain 15 75 5.0E-12 T 12-10-2018 TL08_22310 d39de3631a5925185392e4b2b760ae06 292 SMART SM00530 19 74 0.0076 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_22310 d39de3631a5925185392e4b2b760ae06 292 Gene3D G3DSA:1.10.260.40 5 78 2.7E-6 T 12-10-2018 TL08_23240 b79f462d329f2bf7d748457580a642b7 491 Gene3D G3DSA:3.30.559.30 232 489 2.9E-5 T 12-10-2018 TL08_23240 b79f462d329f2bf7d748457580a642b7 491 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 289 6.9E-76 T 12-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 TL08_23240 b79f462d329f2bf7d748457580a642b7 491 Pfam PF06974 Protein of unknown function (DUF1298) 342 487 6.4E-27 T 12-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 TL08_23240 b79f462d329f2bf7d748457580a642b7 491 SUPERFAMILY SSF52777 54 164 4.0E-6 T 12-10-2018 TL08_23240 b79f462d329f2bf7d748457580a642b7 491 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 5 489 1.9E-138 T 12-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 TL08_14860 85c608f45f3642cee976d6c5a33fd6c8 404 Pfam PF00668 Condensation domain 11 297 9.7E-22 T 12-10-2018 IPR001242 Condensation domain TL08_14860 85c608f45f3642cee976d6c5a33fd6c8 404 Gene3D G3DSA:3.30.559.10 9 358 2.6E-37 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TL08_14860 85c608f45f3642cee976d6c5a33fd6c8 404 Gene3D G3DSA:3.30.559.30 180 385 2.6E-37 T 12-10-2018 TL08_14860 85c608f45f3642cee976d6c5a33fd6c8 404 SUPERFAMILY SSF52777 185 386 6.67E-15 T 12-10-2018 TL08_14860 85c608f45f3642cee976d6c5a33fd6c8 404 SUPERFAMILY SSF52777 9 176 2.0E-20 T 12-10-2018 TL08_22560 3d9a06d87e0f38eddf4caf7dc164645a 83 Gene3D G3DSA:3.30.70.920 2 73 2.0E-19 T 12-10-2018 TL08_22560 3d9a06d87e0f38eddf4caf7dc164645a 83 Pfam PF01037 Lrp/AsnC ligand binding domain 6 75 4.9E-13 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TL08_22560 3d9a06d87e0f38eddf4caf7dc164645a 83 SUPERFAMILY SSF54909 2 76 3.62E-14 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_26850 bee95d21e95e9924b7900939b36f5035 82 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 79 2.3E-27 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 ProSitePatterns PS00057 Ribosomal protein S18 signature. 28 51 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 Pfam PF01084 Ribosomal protein S18 26 75 3.0E-23 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 6.2E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 6.2E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 6.2E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 6.2E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 80 20.045 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 79 5.0E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 SUPERFAMILY SSF46911 5 79 2.49E-24 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26850 bee95d21e95e9924b7900939b36f5035 82 Gene3D G3DSA:4.10.640.10 1 82 3.7E-27 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_07730 db1d8a4915eb4ff64b79fe84f71a7110 147 Gene3D G3DSA:1.10.1660.10 2 54 1.1E-12 T 12-10-2018 TL08_07730 db1d8a4915eb4ff64b79fe84f71a7110 147 Pfam PF12728 Helix-turn-helix domain 5 51 5.1E-16 T 12-10-2018 TL08_07730 db1d8a4915eb4ff64b79fe84f71a7110 147 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 51 2.0E-14 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TL08_07730 db1d8a4915eb4ff64b79fe84f71a7110 147 SUPERFAMILY SSF46955 5 51 4.58E-11 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_04430 f5d641d9bbbccc2baa2e599fc7d98dfe 595 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 113 509 2.4E-57 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_04430 f5d641d9bbbccc2baa2e599fc7d98dfe 595 Gene3D G3DSA:3.10.105.10 347 562 6.5E-45 T 12-10-2018 TL08_04430 f5d641d9bbbccc2baa2e599fc7d98dfe 595 SUPERFAMILY SSF53850 61 592 7.96E-78 T 12-10-2018 TL08_04430 f5d641d9bbbccc2baa2e599fc7d98dfe 595 Gene3D G3DSA:3.40.190.10 253 346 1.5E-13 T 12-10-2018 TL08_04430 f5d641d9bbbccc2baa2e599fc7d98dfe 595 PIRSF PIRSF002741 241 594 1.3E-42 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_04430 f5d641d9bbbccc2baa2e599fc7d98dfe 595 PIRSF PIRSF002741 14 227 5.0E-5 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_04430 f5d641d9bbbccc2baa2e599fc7d98dfe 595 Gene3D G3DSA:3.90.76.10 95 212 7.0E-18 T 12-10-2018 TL08_08425 ae899e337f375b43edc2ae000dad95f3 259 Pfam PF11361 Protein of unknown function (DUF3159) 44 226 2.4E-67 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 TL08_08425 ae899e337f375b43edc2ae000dad95f3 259 PIRSF PIRSF010219 20 243 8.1E-75 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 TL08_19295 f8654f7454427beee1759d3273197145 484 Gene3D G3DSA:3.40.50.2300 1 103 1.1E-37 T 12-10-2018 TL08_19295 f8654f7454427beee1759d3273197145 484 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 87 5.6E-30 T 12-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 TL08_19295 f8654f7454427beee1759d3273197145 484 SUPERFAMILY SSF52794 2 100 1.17E-32 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 TL08_19295 f8654f7454427beee1759d3273197145 484 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 89 1.8E-18 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TL08_19295 f8654f7454427beee1759d3273197145 484 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 128 462 1.6E-104 T 12-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 TL08_16585 832aef5390df2466f1041359df84c669 467 SUPERFAMILY SSF103473 64 443 8.76E-46 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_16585 832aef5390df2466f1041359df84c669 467 Gene3D G3DSA:1.20.1250.20 61 445 6.3E-39 T 12-10-2018 TL08_16585 832aef5390df2466f1041359df84c669 467 Pfam PF05977 Transmembrane secretion effector 63 445 1.2E-36 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_24280 93d73ccfe137f4b351ff516d360b9b66 380 SUPERFAMILY SSF52949 2 148 2.02E-40 T 12-10-2018 TL08_24280 93d73ccfe137f4b351ff516d360b9b66 380 SMART SM00506 1 132 5.9E-19 T 12-10-2018 IPR002589 Macro domain TL08_24280 93d73ccfe137f4b351ff516d360b9b66 380 Gene3D G3DSA:3.40.220.10 1 147 2.5E-41 T 12-10-2018 TL08_24280 93d73ccfe137f4b351ff516d360b9b66 380 Pfam PF01661 Macro domain 18 129 1.6E-23 T 12-10-2018 IPR002589 Macro domain TL08_23620 7d2e89b02435a946639cf1ebd8e041a4 546 Gene3D G3DSA:3.90.226.10 9 276 1.2E-93 T 12-10-2018 TL08_23620 7d2e89b02435a946639cf1ebd8e041a4 546 SUPERFAMILY SSF52096 24 274 3.32E-76 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_23620 7d2e89b02435a946639cf1ebd8e041a4 546 SUPERFAMILY SSF52096 295 546 2.49E-86 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_23620 7d2e89b02435a946639cf1ebd8e041a4 546 Gene3D G3DSA:3.90.226.10 279 546 3.4E-92 T 12-10-2018 TL08_23620 7d2e89b02435a946639cf1ebd8e041a4 546 Pfam PF01039 Carboxyl transferase domain 46 544 7.6E-194 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TL08_18930 1101fdadb3692013caca2362a959894e 311 Gene3D G3DSA:3.30.1330.60 145 311 1.1E-5 T 12-10-2018 IPR036737 OmpA-like domain superfamily TL08_25255 89a49c20a4225d7777f047de0ba57008 306 SUPERFAMILY SSF56784 26 272 1.89E-66 T 12-10-2018 IPR036412 HAD-like superfamily TL08_25255 89a49c20a4225d7777f047de0ba57008 306 Pfam PF13344 Haloacid dehalogenase-like hydrolase 27 125 5.9E-23 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TL08_25255 89a49c20a4225d7777f047de0ba57008 306 PIRSF PIRSF000915 24 276 7.2E-53 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TL08_25255 89a49c20a4225d7777f047de0ba57008 306 Pfam PF13242 HAD-hyrolase-like 198 271 2.8E-23 T 12-10-2018 TL08_25255 89a49c20a4225d7777f047de0ba57008 306 Gene3D G3DSA:3.40.50.1000 103 198 4.4E-77 T 12-10-2018 IPR023214 HAD superfamily TL08_25255 89a49c20a4225d7777f047de0ba57008 306 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 27 247 1.3E-45 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TL08_25255 89a49c20a4225d7777f047de0ba57008 306 Gene3D G3DSA:3.40.50.1000 26 261 4.4E-77 T 12-10-2018 IPR023214 HAD superfamily TL08_14005 2cd792efca69044d80a67f71c87d0e40 196 Pfam PF01381 Helix-turn-helix 18 72 1.8E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_14005 2cd792efca69044d80a67f71c87d0e40 196 SUPERFAMILY SSF47413 12 76 1.72E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_14005 2cd792efca69044d80a67f71c87d0e40 196 SUPERFAMILY SSF51182 69 180 1.13E-23 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_14005 2cd792efca69044d80a67f71c87d0e40 196 Pfam PF07883 Cupin domain 117 180 5.8E-15 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TL08_14005 2cd792efca69044d80a67f71c87d0e40 196 Gene3D G3DSA:1.10.260.40 10 79 1.2E-17 T 12-10-2018 TL08_14005 2cd792efca69044d80a67f71c87d0e40 196 Gene3D G3DSA:2.60.120.10 101 188 1.2E-15 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_14005 2cd792efca69044d80a67f71c87d0e40 196 SMART SM00530 17 72 7.8E-17 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_05960 671b7852c17f85487153a51c34f12a69 398 Pfam PF00067 Cytochrome P450 207 368 3.6E-24 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 SUPERFAMILY SSF48264 5 398 2.62E-95 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00359 B-class P450 signature 289 316 5.8E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00359 B-class P450 signature 91 102 5.8E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00359 B-class P450 signature 338 347 5.8E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00359 B-class P450 signature 155 170 5.8E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00359 B-class P450 signature 347 358 5.8E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00359 B-class P450 signature 271 282 5.8E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00359 B-class P450 signature 192 214 5.8E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00359 B-class P450 signature 138 154 5.8E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00359 B-class P450 signature 317 332 5.8E-57 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00385 P450 superfamily signature 236 253 3.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00385 P450 superfamily signature 347 358 3.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00385 P450 superfamily signature 271 282 3.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 PRINTS PR00385 P450 superfamily signature 338 347 3.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_05960 671b7852c17f85487153a51c34f12a69 398 Gene3D G3DSA:1.10.630.10 5 398 1.9E-121 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_11865 f6ae6b92f4143f0b8c3155912bf9ea05 305 SMART SM00849 63 277 2.8E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_11865 f6ae6b92f4143f0b8c3155912bf9ea05 305 Gene3D G3DSA:3.60.15.10 3 299 1.7E-74 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_11865 f6ae6b92f4143f0b8c3155912bf9ea05 305 SUPERFAMILY SSF56281 63 286 7.34E-36 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_11865 f6ae6b92f4143f0b8c3155912bf9ea05 305 Pfam PF00753 Metallo-beta-lactamase superfamily 65 277 1.9E-28 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_12160 cf9cf7c5c0c32350ceff58658827b4a6 237 SMART SM00382 44 228 6.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12160 cf9cf7c5c0c32350ceff58658827b4a6 237 Pfam PF00005 ABC transporter 36 181 2.6E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12160 cf9cf7c5c0c32350ceff58658827b4a6 237 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12160 cf9cf7c5c0c32350ceff58658827b4a6 237 Gene3D G3DSA:3.40.50.300 13 236 3.9E-58 T 12-10-2018 TL08_12160 cf9cf7c5c0c32350ceff58658827b4a6 237 SUPERFAMILY SSF52540 15 232 3.24E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20390 ac1e267c598763bc123a495f829e5e06 370 SUPERFAMILY SSF53067 3 125 3.88E-20 T 12-10-2018 TL08_20390 ac1e267c598763bc123a495f829e5e06 370 Pfam PF02541 Ppx/GppA phosphatase family 30 301 1.0E-46 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 TL08_20390 ac1e267c598763bc123a495f829e5e06 370 Gene3D G3DSA:3.30.420.150 108 290 9.9E-57 T 12-10-2018 TL08_20390 ac1e267c598763bc123a495f829e5e06 370 SUPERFAMILY SSF53067 131 302 2.7E-25 T 12-10-2018 TL08_20390 ac1e267c598763bc123a495f829e5e06 370 Gene3D G3DSA:3.30.420.40 4 297 9.9E-57 T 12-10-2018 TL08_15450 32da83501087cc9f1c0cb37bfa9355f1 133 SUPERFAMILY SSF54593 12 131 7.79E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_15450 32da83501087cc9f1c0cb37bfa9355f1 133 Gene3D G3DSA:3.10.180.10 16 133 8.0E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_15855 9ff1c3f61056b30b974808b695526fee 69 SUPERFAMILY SSF54862 9 68 8.39E-14 T 12-10-2018 TL08_15855 9ff1c3f61056b30b974808b695526fee 69 Pfam PF06902 Divergent 4Fe-4S mono-cluster 10 68 9.4E-13 T 12-10-2018 IPR010693 Divergent 4Fe-4S mono-cluster TL08_15855 9ff1c3f61056b30b974808b695526fee 69 Gene3D G3DSA:3.30.70.20 9 69 9.4E-19 T 12-10-2018 TL08_15855 9ff1c3f61056b30b974808b695526fee 69 PRINTS PR00352 3Fe-4S ferredoxin signature 54 66 7.2E-7 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_15855 9ff1c3f61056b30b974808b695526fee 69 PRINTS PR00352 3Fe-4S ferredoxin signature 12 23 7.2E-7 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_15855 9ff1c3f61056b30b974808b695526fee 69 PRINTS PR00352 3Fe-4S ferredoxin signature 23 33 7.2E-7 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_07515 f02a60d656995c7aa10bb1ccf43afec5 487 Pfam PF04228 Putative neutral zinc metallopeptidase 43 267 9.7E-6 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative TL08_07515 f02a60d656995c7aa10bb1ccf43afec5 487 SUPERFAMILY SSF55486 47 216 5.28E-14 T 12-10-2018 TL08_05325 f7f00652c5fce88883f4cbf388858eb1 432 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 157 384 7.6E-25 T 12-10-2018 IPR018713 Domain of unknown function DUF2236 TL08_02020 d6b7034f9cdd911c446277ac77140ef5 265 Pfam PF11361 Protein of unknown function (DUF3159) 28 212 1.1E-49 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 TL08_03475 cf3f01d91041923359dde836a1cd29b1 427 SUPERFAMILY SSF53474 42 420 1.01E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_03475 cf3f01d91041923359dde836a1cd29b1 427 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 59 2.6E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TL08_03475 cf3f01d91041923359dde836a1cd29b1 427 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 140 154 2.6E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TL08_03475 cf3f01d91041923359dde836a1cd29b1 427 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 81 92 2.6E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TL08_03475 cf3f01d91041923359dde836a1cd29b1 427 Pfam PF00561 alpha/beta hydrolase fold 49 245 1.8E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_01615 9989e466af98579aca989bc004896a59 275 Pfam PF00440 Bacterial regulatory proteins, tetR family 82 122 2.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_01615 9989e466af98579aca989bc004896a59 275 Gene3D G3DSA:1.10.10.60 65 116 1.7E-20 T 12-10-2018 TL08_01615 9989e466af98579aca989bc004896a59 275 Gene3D G3DSA:1.10.357.10 117 262 3.7E-34 T 12-10-2018 TL08_01615 9989e466af98579aca989bc004896a59 275 SUPERFAMILY SSF46689 72 139 5.13E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_01615 9989e466af98579aca989bc004896a59 275 SUPERFAMILY SSF48498 148 261 3.86E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_02795 4e00a2fbc0154d80c18e0c94e5ca9bdc 1233 PRINTS PR00723 Subtilisin serine protease family (S8) signature 221 240 1.6E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_02795 4e00a2fbc0154d80c18e0c94e5ca9bdc 1233 PRINTS PR00723 Subtilisin serine protease family (S8) signature 258 271 1.6E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_02795 4e00a2fbc0154d80c18e0c94e5ca9bdc 1233 PRINTS PR00723 Subtilisin serine protease family (S8) signature 434 450 1.6E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_02795 4e00a2fbc0154d80c18e0c94e5ca9bdc 1233 Pfam PF00082 Subtilase family 221 484 3.6E-57 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_02795 4e00a2fbc0154d80c18e0c94e5ca9bdc 1233 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 262 272 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_02795 4e00a2fbc0154d80c18e0c94e5ca9bdc 1233 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 435 445 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_02795 4e00a2fbc0154d80c18e0c94e5ca9bdc 1233 SUPERFAMILY SSF52743 202 493 3.14E-84 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_02795 4e00a2fbc0154d80c18e0c94e5ca9bdc 1233 Gene3D G3DSA:3.40.50.200 195 495 8.1E-96 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_06240 bf9047e97f79de4b16b8dc2f1959c087 391 Gene3D G3DSA:2.60.110.10 51 370 1.9E-99 T 12-10-2018 IPR037176 Osmotin/thaumatin-like superfamily TL08_06240 bf9047e97f79de4b16b8dc2f1959c087 391 Gene3D G3DSA:3.30.920.50 239 345 1.9E-99 T 12-10-2018 TL08_06240 bf9047e97f79de4b16b8dc2f1959c087 391 Pfam PF16483 Beta-1,3-glucanase 45 388 7.0E-99 T 12-10-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 TL08_20290 a890c0bc66a210212d5671320cd1e2fb 448 SUPERFAMILY SSF55931 21 433 2.35E-41 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TL08_20290 a890c0bc66a210212d5671320cd1e2fb 448 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 79 343 1.1E-36 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TL08_20290 a890c0bc66a210212d5671320cd1e2fb 448 PIRSF PIRSF017901 2 448 1.9E-94 T 12-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TL08_20290 a890c0bc66a210212d5671320cd1e2fb 448 Gene3D G3DSA:3.30.590.20 1 446 7.9E-113 T 12-10-2018 TL08_23190 6adae7f875285add311ed158ba39ed83 158 SUPERFAMILY SSF55826 6 156 3.01E-43 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TL08_23190 6adae7f875285add311ed158ba39ed83 158 Pfam PF04073 Aminoacyl-tRNA editing domain 35 147 4.0E-25 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TL08_23190 6adae7f875285add311ed158ba39ed83 158 Gene3D G3DSA:3.90.960.10 2 158 2.8E-56 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TL08_23190 6adae7f875285add311ed158ba39ed83 158 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 157 2.2E-54 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC TL08_23190 6adae7f875285add311ed158ba39ed83 158 PIRSF PIRSF006181 2 158 4.4E-51 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC TL08_16480 97b03264c54210bd9e0c5bf51f830f13 793 SMART SM00530 8 64 1.1E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_16480 97b03264c54210bd9e0c5bf51f830f13 793 Pfam PF13560 Helix-turn-helix domain 4 67 1.2E-14 T 12-10-2018 TL08_16480 97b03264c54210bd9e0c5bf51f830f13 793 Gene3D G3DSA:1.10.260.40 2 67 6.7E-13 T 12-10-2018 TL08_16480 97b03264c54210bd9e0c5bf51f830f13 793 SUPERFAMILY SSF47413 2 63 5.63E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_15535 b41c134064d74a6bb1323b2d39ce15e6 132 SUPERFAMILY SSF54593 3 128 2.06E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_15535 b41c134064d74a6bb1323b2d39ce15e6 132 Gene3D G3DSA:3.10.180.10 1 130 4.5E-40 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_15535 b41c134064d74a6bb1323b2d39ce15e6 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 2.5E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_19385 bde9c2bf32fbdf324c6c7bfbb92bb071 434 SUPERFAMILY SSF51445 17 362 2.84E-13 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_19385 bde9c2bf32fbdf324c6c7bfbb92bb071 434 Pfam PF12876 Sugar-binding cellulase-like 15 128 3.8E-11 T 12-10-2018 IPR024778 Putative cellulase TL08_19385 bde9c2bf32fbdf324c6c7bfbb92bb071 434 Gene3D G3DSA:3.20.20.80 7 267 1.5E-45 T 12-10-2018 TL08_19385 bde9c2bf32fbdf324c6c7bfbb92bb071 434 Gene3D G3DSA:3.20.20.80 289 430 1.4E-10 T 12-10-2018 TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 SUPERFAMILY SSF49452 501 579 8.44E-11 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 Gene3D G3DSA:3.40.50.200 181 495 4.8E-64 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 Pfam PF13620 Carboxypeptidase regulatory-like domain 587 663 5.8E-15 T 12-10-2018 TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 Pfam PF13620 Carboxypeptidase regulatory-like domain 506 580 2.3E-11 T 12-10-2018 TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 Gene3D G3DSA:2.60.40.1120 588 675 3.1E-12 T 12-10-2018 TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 SUPERFAMILY SSF49452 583 656 4.12E-13 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 429 439 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 256 266 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 Gene3D G3DSA:2.60.40.1120 506 581 6.7E-13 T 12-10-2018 TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 Pfam PF00082 Subtilase family 198 453 6.4E-37 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 PRINTS PR00723 Subtilisin serine protease family (S8) signature 252 265 1.7E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 PRINTS PR00723 Subtilisin serine protease family (S8) signature 198 217 1.7E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 PRINTS PR00723 Subtilisin serine protease family (S8) signature 428 444 1.7E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_10605 bd67897f112aedc59cddd5d39e147a09 866 SUPERFAMILY SSF52743 178 497 1.07E-57 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_13170 0233657279927e909b03355d789297a3 674 SMART SM00327 485 667 7.4E-12 T 12-10-2018 IPR002035 von Willebrand factor, type A TL08_13170 0233657279927e909b03355d789297a3 674 Gene3D G3DSA:3.40.50.410 481 666 1.2E-17 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_13170 0233657279927e909b03355d789297a3 674 Pfam PF13519 von Willebrand factor type A domain 488 585 1.4E-6 T 12-10-2018 IPR002035 von Willebrand factor, type A TL08_13170 0233657279927e909b03355d789297a3 674 SUPERFAMILY SSF53300 487 659 3.18E-17 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_03520 337b93d3de4f8ebd3bdca692e48ed08d 150 Pfam PF00005 ABC transporter 22 149 1.8E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_03520 337b93d3de4f8ebd3bdca692e48ed08d 150 Gene3D G3DSA:3.40.50.300 1 150 4.2E-36 T 12-10-2018 TL08_03520 337b93d3de4f8ebd3bdca692e48ed08d 150 SUPERFAMILY SSF52540 2 149 9.94E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 554 562 9.6E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 574 593 9.6E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 500 511 9.6E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 SUPERFAMILY SSF53639 4 213 4.71E-30 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 Gene3D G3DSA:3.40.50.720 402 681 2.6E-57 T 12-10-2018 TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 SUPERFAMILY SSF51735 414 681 4.39E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 8 684 0.0 T 12-10-2018 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 Gene3D G3DSA:3.40.225.10 6 217 4.6E-51 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 Pfam PF00106 short chain dehydrogenase 422 607 2.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 548 564 3.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 500 511 3.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 595 612 3.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 422 439 3.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 574 593 3.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 421 611 0.006 T 12-10-2018 TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 208 1.9E-23 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TL08_20735 2b6931ad17b23b2be193c768b0df4180 684 SMART SM01007 9 211 4.5E-31 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TL08_06775 f143425b8ad0108b5fd27ff273b8c6af 295 Gene3D G3DSA:3.30.450.40 121 294 1.6E-53 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_06775 f143425b8ad0108b5fd27ff273b8c6af 295 SUPERFAMILY SSF46785 48 119 7.34E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_06775 f143425b8ad0108b5fd27ff273b8c6af 295 Pfam PF01614 Bacterial transcriptional regulator 166 287 1.5E-35 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_06775 f143425b8ad0108b5fd27ff273b8c6af 295 Gene3D G3DSA:1.10.10.10 45 120 2.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06775 f143425b8ad0108b5fd27ff273b8c6af 295 Pfam PF09339 IclR helix-turn-helix domain 50 99 1.2E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_06775 f143425b8ad0108b5fd27ff273b8c6af 295 SUPERFAMILY SSF55781 105 292 1.96E-49 T 12-10-2018 TL08_06775 f143425b8ad0108b5fd27ff273b8c6af 295 SMART SM00346 48 137 1.0E-20 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_07210 de4d5a95a1028090e7ea8c3ee7e22e98 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 34 146 1.2E-29 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_07210 de4d5a95a1028090e7ea8c3ee7e22e98 148 Gene3D G3DSA:2.30.110.10 10 148 4.5E-45 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_07210 de4d5a95a1028090e7ea8c3ee7e22e98 148 Pfam PF04075 F420H(2)-dependent quinone reductase 19 147 9.0E-32 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_06815 0e6c26980be67c7388b1fe7ae0074688 208 SUPERFAMILY SSF53597 1 191 1.27E-25 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_06815 0e6c26980be67c7388b1fe7ae0074688 208 Gene3D G3DSA:3.40.430.10 1 190 2.9E-35 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_06815 0e6c26980be67c7388b1fe7ae0074688 208 Pfam PF01872 RibD C-terminal domain 2 186 1.6E-21 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TL08_14150 d34276e8add30ade0c7fc6bfdc2db75b 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 53 1.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14150 d34276e8add30ade0c7fc6bfdc2db75b 195 SUPERFAMILY SSF46689 2 74 5.64E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14150 d34276e8add30ade0c7fc6bfdc2db75b 195 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 81 192 2.7E-9 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal TL08_14150 d34276e8add30ade0c7fc6bfdc2db75b 195 SUPERFAMILY SSF48498 79 193 6.04E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_14150 d34276e8add30ade0c7fc6bfdc2db75b 195 Gene3D G3DSA:1.10.357.10 1 190 2.9E-39 T 12-10-2018 TL08_13280 b9f78fd233e5d76afef53d50dd95f823 482 Pfam PF07690 Major Facilitator Superfamily 92 379 2.8E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_13280 b9f78fd233e5d76afef53d50dd95f823 482 Gene3D G3DSA:1.20.1250.20 286 475 6.7E-17 T 12-10-2018 TL08_13280 b9f78fd233e5d76afef53d50dd95f823 482 Gene3D G3DSA:1.20.1250.20 82 268 2.9E-13 T 12-10-2018 TL08_13280 b9f78fd233e5d76afef53d50dd95f823 482 SUPERFAMILY SSF103473 73 468 6.54E-43 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_02360 812f1ff616becb0b3eecc35e8c76b1c3 561 SUPERFAMILY SSF56524 270 457 4.84E-55 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TL08_02360 812f1ff616becb0b3eecc35e8c76b1c3 561 Gene3D G3DSA:3.90.420.10 252 453 1.2E-48 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TL08_02360 812f1ff616becb0b3eecc35e8c76b1c3 561 Gene3D G3DSA:2.60.40.650 454 559 1.2E-24 T 12-10-2018 TL08_02360 812f1ff616becb0b3eecc35e8c76b1c3 561 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 456 545 9.7E-6 T 12-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 TL08_02360 812f1ff616becb0b3eecc35e8c76b1c3 561 Pfam PF00174 Oxidoreductase molybdopterin binding domain 287 439 3.4E-37 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TL08_02360 812f1ff616becb0b3eecc35e8c76b1c3 561 SUPERFAMILY SSF81296 450 558 1.61E-23 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_21940 ea0c21030f3dcaeb0d85ba6bfffb3137 313 SUPERFAMILY SSF81324 14 229 3.4E-35 T 12-10-2018 TL08_21940 ea0c21030f3dcaeb0d85ba6bfffb3137 313 Pfam PF00520 Ion transport protein 14 223 3.1E-45 T 12-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 TL08_21940 ea0c21030f3dcaeb0d85ba6bfffb3137 313 Gene3D G3DSA:1.20.120.350 4 116 1.9E-28 T 12-10-2018 IPR027359 Voltage-dependent channel domain superfamily TL08_21940 ea0c21030f3dcaeb0d85ba6bfffb3137 313 Gene3D G3DSA:1.10.287.70 117 214 2.1E-31 T 12-10-2018 TL08_24425 b3b2476c8bfa89ad6cd34e05973275c3 145 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 23 126 8.9E-23 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24425 b3b2476c8bfa89ad6cd34e05973275c3 145 Gene3D G3DSA:1.20.1300.10 25 135 4.1E-17 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24425 b3b2476c8bfa89ad6cd34e05973275c3 145 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 24 127 9.9E-28 T 12-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_24425 b3b2476c8bfa89ad6cd34e05973275c3 145 SUPERFAMILY SSF81343 23 129 1.23E-26 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_09650 1986758869950454dfb9aba086b73a8d 542 Pfam PF00890 FAD binding domain 10 393 4.2E-86 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_09650 1986758869950454dfb9aba086b73a8d 542 Pfam PF02910 Fumarate reductase flavoprotein C-term 482 527 3.9E-9 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_09650 1986758869950454dfb9aba086b73a8d 542 SUPERFAMILY SSF56425 233 353 2.54E-34 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_09650 1986758869950454dfb9aba086b73a8d 542 SUPERFAMILY SSF46977 437 528 7.72E-20 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_09650 1986758869950454dfb9aba086b73a8d 542 Gene3D G3DSA:3.50.50.60 10 403 2.5E-138 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09650 1986758869950454dfb9aba086b73a8d 542 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 8 509 1.3E-158 T 12-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 TL08_09650 1986758869950454dfb9aba086b73a8d 542 Gene3D G3DSA:3.90.700.10 243 348 2.5E-138 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TL08_09650 1986758869950454dfb9aba086b73a8d 542 SUPERFAMILY SSF51905 3 409 2.48E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09650 1986758869950454dfb9aba086b73a8d 542 Gene3D G3DSA:1.20.58.100 427 526 3.6E-13 T 12-10-2018 TL08_09650 1986758869950454dfb9aba086b73a8d 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 5.3E-7 T 12-10-2018 TL08_09650 1986758869950454dfb9aba086b73a8d 542 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 371 378 5.3E-7 T 12-10-2018 TL08_09650 1986758869950454dfb9aba086b73a8d 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 329 345 1.5E-11 T 12-10-2018 TL08_09650 1986758869950454dfb9aba086b73a8d 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.5E-11 T 12-10-2018 TL08_09650 1986758869950454dfb9aba086b73a8d 542 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 1.5E-11 T 12-10-2018 TL08_03525 bc20732c9d9a953df021b66800c593f7 212 Pfam PF03551 Transcriptional regulator PadR-like family 39 114 8.7E-8 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal TL08_03525 bc20732c9d9a953df021b66800c593f7 212 Gene3D G3DSA:1.10.10.10 33 122 4.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03525 bc20732c9d9a953df021b66800c593f7 212 SUPERFAMILY SSF46785 34 209 8.84E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_12720 2097c3ef8d31369cbf66e10c7707e154 395 Gene3D G3DSA:1.20.140.10 218 395 4.8E-52 T 12-10-2018 TL08_12720 2097c3ef8d31369cbf66e10c7707e154 395 PIRSF PIRSF016578 1 391 2.9E-31 T 12-10-2018 TL08_12720 2097c3ef8d31369cbf66e10c7707e154 395 SUPERFAMILY SSF47203 234 390 8.86E-17 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_12720 2097c3ef8d31369cbf66e10c7707e154 395 Gene3D G3DSA:1.10.540.10 9 116 1.4E-21 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_12720 2097c3ef8d31369cbf66e10c7707e154 395 SUPERFAMILY SSF56645 14 213 3.14E-35 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_12720 2097c3ef8d31369cbf66e10c7707e154 395 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 370 2.1E-15 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain TL08_12720 2097c3ef8d31369cbf66e10c7707e154 395 Gene3D G3DSA:2.40.110.10 118 214 1.2E-20 T 12-10-2018 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 Pfam PF09190 DALR domain 322 379 1.0E-9 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 1 286 1.7E-118 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 197 218 4.9E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 3 14 4.9E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 39 48 4.9E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 166 184 4.9E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 SUPERFAMILY SSF47323 308 449 3.27E-30 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 450 33.348 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 1 448 4.1E-132 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 Gene3D G3DSA:1.20.120.640 280 450 1.3E-34 T 12-10-2018 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 Gene3D G3DSA:3.40.50.620 1 279 2.3E-116 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 SUPERFAMILY SSF52374 2 285 2.23E-87 T 12-10-2018 TL08_01865 f7c66c6d69d756a37b8e57fd3706db36 453 SMART SM00840 322 387 1.7E-11 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TL08_10920 993b3f11d95110d2ad0fae9ad88435e4 145 Pfam PF01957 NfeD-like C-terminal, partner-binding 8 143 5.2E-20 T 12-10-2018 IPR002810 NfeD-like, C-terminal domain TL08_10920 993b3f11d95110d2ad0fae9ad88435e4 145 Gene3D G3DSA:2.40.50.140 83 144 1.4E-18 T 12-10-2018 TL08_23910 cb4ec4550de5cc1658b7d0ec6ccaf8cf 417 SUPERFAMILY SSF46785 14 75 6.52E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23910 cb4ec4550de5cc1658b7d0ec6ccaf8cf 417 Pfam PF00480 ROK family 88 393 1.9E-47 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_23910 cb4ec4550de5cc1658b7d0ec6ccaf8cf 417 Gene3D G3DSA:3.30.420.40 94 390 7.0E-78 T 12-10-2018 TL08_23910 cb4ec4550de5cc1658b7d0ec6ccaf8cf 417 SUPERFAMILY SSF53067 88 399 4.24E-42 T 12-10-2018 TL08_23910 cb4ec4550de5cc1658b7d0ec6ccaf8cf 417 Gene3D G3DSA:3.30.420.40 214 381 7.0E-78 T 12-10-2018 TL08_23910 cb4ec4550de5cc1658b7d0ec6ccaf8cf 417 Gene3D G3DSA:1.10.10.10 4 81 2.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18800 f400acdab79f3e48c3d55a03c5dcf274 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_18800 f400acdab79f3e48c3d55a03c5dcf274 345 Pfam PF00107 Zinc-binding dehydrogenase 184 304 2.9E-14 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_18800 f400acdab79f3e48c3d55a03c5dcf274 345 SMART SM00829 11 339 6.6E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_18800 f400acdab79f3e48c3d55a03c5dcf274 345 Gene3D G3DSA:3.40.50.720 158 311 3.8E-113 T 12-10-2018 TL08_18800 f400acdab79f3e48c3d55a03c5dcf274 345 Gene3D G3DSA:3.90.180.10 15 339 3.8E-113 T 12-10-2018 TL08_18800 f400acdab79f3e48c3d55a03c5dcf274 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 142 2.3E-26 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_18800 f400acdab79f3e48c3d55a03c5dcf274 345 SUPERFAMILY SSF50129 15 167 1.98E-44 T 12-10-2018 IPR011032 GroES-like superfamily TL08_18800 f400acdab79f3e48c3d55a03c5dcf274 345 SUPERFAMILY SSF51735 147 309 3.27E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 456 4.0E-20 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 SUPERFAMILY SSF51905 3 337 9.36E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 SUPERFAMILY SSF55424 347 461 3.61E-25 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PIRSF PIRSF000350 1 457 9.2E-79 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 Gene3D G3DSA:3.30.390.30 341 462 1.5E-32 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 1.1E-34 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 1.1E-34 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 1.1E-34 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.1E-34 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 1.1E-34 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 Gene3D G3DSA:3.50.50.60 155 273 1.2E-104 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 328 1.2E-57 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 1.4E-49 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.4E-49 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 1.4E-49 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.4E-49 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 1.4E-49 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.4E-49 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.4E-49 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 1.4E-49 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.4E-49 T 12-10-2018 TL08_23780 1369dfedb368744a38de9bb0212c2c80 467 Gene3D G3DSA:3.50.50.60 4 331 1.2E-104 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_18890 f7221dd14aee4fbdea8260d10ffb3b84 672 SUPERFAMILY SSF81345 346 667 9.02E-75 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_18890 f7221dd14aee4fbdea8260d10ffb3b84 672 SUPERFAMILY SSF81345 4 324 1.2E-52 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_18890 f7221dd14aee4fbdea8260d10ffb3b84 672 Pfam PF01032 FecCD transport family 11 325 2.8E-65 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_18890 f7221dd14aee4fbdea8260d10ffb3b84 672 Pfam PF01032 FecCD transport family 363 667 1.6E-84 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_18890 f7221dd14aee4fbdea8260d10ffb3b84 672 Gene3D G3DSA:1.10.3470.10 1 330 1.1E-71 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_18890 f7221dd14aee4fbdea8260d10ffb3b84 672 Gene3D G3DSA:1.10.3470.10 346 672 3.1E-89 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 Gene3D G3DSA:3.40.50.720 1 243 1.6E-77 T 12-10-2018 TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 4.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 SUPERFAMILY SSF51735 5 241 2.26E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 3.4E-62 T 12-10-2018 TL08_05170 3b0e21a1fcbff381886b87b2de44ede9 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_05110 88bc95b14926887694389b9f5dda1016 310 SUPERFAMILY SSF51679 10 304 2.75E-44 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_05110 88bc95b14926887694389b9f5dda1016 310 Gene3D G3DSA:3.20.20.30 2 304 1.7E-56 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_05110 88bc95b14926887694389b9f5dda1016 310 Pfam PF00296 Luciferase-like monooxygenase 8 284 3.6E-40 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_08090 2a8b653fb3310ddd62e3a2516733c702 782 Pfam PF00384 Molybdopterin oxidoreductase 121 502 8.5E-29 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_08090 2a8b653fb3310ddd62e3a2516733c702 782 SUPERFAMILY SSF53706 59 644 5.89E-143 T 12-10-2018 TL08_08090 2a8b653fb3310ddd62e3a2516733c702 782 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 770 1.1E-296 T 12-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 TL08_08090 2a8b653fb3310ddd62e3a2516733c702 782 PIRSF PIRSF000144 3 775 0.0 T 12-10-2018 TL08_08090 2a8b653fb3310ddd62e3a2516733c702 782 Gene3D G3DSA:3.40.50.740 133 598 7.6E-78 T 12-10-2018 TL08_08090 2a8b653fb3310ddd62e3a2516733c702 782 Gene3D G3DSA:3.40.228.10 197 419 7.6E-78 T 12-10-2018 TL08_08090 2a8b653fb3310ddd62e3a2516733c702 782 Pfam PF01568 Molydopterin dinucleotide binding domain 653 763 3.5E-9 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TL08_08090 2a8b653fb3310ddd62e3a2516733c702 782 SUPERFAMILY SSF50692 649 771 1.54E-14 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TL08_18815 dee8981a6d8ac55d76358b465e68e54a 628 SUPERFAMILY SSF53474 364 623 1.88E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18815 dee8981a6d8ac55d76358b465e68e54a 628 Gene3D G3DSA:2.120.10.30 7 120 1.5E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_18815 dee8981a6d8ac55d76358b465e68e54a 628 Gene3D G3DSA:2.120.10.30 124 264 5.5E-6 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_18815 dee8981a6d8ac55d76358b465e68e54a 628 Pfam PF00326 Prolyl oligopeptidase family 408 624 1.4E-47 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_18815 dee8981a6d8ac55d76358b465e68e54a 628 Gene3D G3DSA:3.40.50.1820 340 626 2.4E-76 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18815 dee8981a6d8ac55d76358b465e68e54a 628 SUPERFAMILY SSF50969 20 247 1.73E-20 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like TL08_18785 31ff305c139153722d2e42d57b38488a 1079 SUPERFAMILY SSF46894 5 88 3.97E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_18785 31ff305c139153722d2e42d57b38488a 1079 SMART SM00862 16 88 1.1E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_18785 31ff305c139153722d2e42d57b38488a 1079 SUPERFAMILY SSF52540 255 525 2.89E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18785 31ff305c139153722d2e42d57b38488a 1079 SUPERFAMILY SSF48452 92 242 9.48E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_18785 31ff305c139153722d2e42d57b38488a 1079 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 77 4.2E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_18785 31ff305c139153722d2e42d57b38488a 1079 Gene3D G3DSA:1.25.40.10 93 256 1.9E-40 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_18785 31ff305c139153722d2e42d57b38488a 1079 SMART SM01043 95 238 8.1E-39 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_18785 31ff305c139153722d2e42d57b38488a 1079 SUPERFAMILY SSF48452 762 916 2.47E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_18785 31ff305c139153722d2e42d57b38488a 1079 Pfam PF03704 Bacterial transcriptional activator domain 95 238 7.4E-32 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_18785 31ff305c139153722d2e42d57b38488a 1079 Gene3D G3DSA:1.10.10.10 1 90 1.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18785 31ff305c139153722d2e42d57b38488a 1079 Gene3D G3DSA:1.25.40.10 750 1047 8.7E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_18785 31ff305c139153722d2e42d57b38488a 1079 PRINTS PR00364 Disease resistance protein signature 353 367 8.2E-6 T 12-10-2018 TL08_18785 31ff305c139153722d2e42d57b38488a 1079 PRINTS PR00364 Disease resistance protein signature 279 294 8.2E-6 T 12-10-2018 TL08_18785 31ff305c139153722d2e42d57b38488a 1079 PRINTS PR00364 Disease resistance protein signature 459 473 8.2E-6 T 12-10-2018 TL08_10650 1c2db083b597c00405bf5b2526fb77c1 273 Gene3D G3DSA:3.40.50.300 1 247 6.2E-62 T 12-10-2018 TL08_10650 1c2db083b597c00405bf5b2526fb77c1 273 SMART SM00382 31 216 8.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_10650 1c2db083b597c00405bf5b2526fb77c1 273 SUPERFAMILY SSF52540 4 231 1.56E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10650 1c2db083b597c00405bf5b2526fb77c1 273 Pfam PF00005 ABC transporter 27 168 1.6E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_10650 1c2db083b597c00405bf5b2526fb77c1 273 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_19565 222be790f2f93890d3281ee96a8d2a08 542 Gene3D G3DSA:3.90.870.20 338 540 5.9E-74 T 12-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily TL08_19565 222be790f2f93890d3281ee96a8d2a08 542 SUPERFAMILY SSF53067 1 325 1.68E-18 T 12-10-2018 TL08_19565 222be790f2f93890d3281ee96a8d2a08 542 SUPERFAMILY SSF55821 369 539 9.77E-6 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TL08_19565 222be790f2f93890d3281ee96a8d2a08 542 Pfam PF16861 Carbamoyltransferase C-terminus 372 541 2.4E-63 T 12-10-2018 IPR031730 Carbamoyltransferase, C-terminal TL08_19565 222be790f2f93890d3281ee96a8d2a08 542 Gene3D G3DSA:3.30.420.350 122 316 2.3E-91 T 12-10-2018 TL08_19565 222be790f2f93890d3281ee96a8d2a08 542 Gene3D G3DSA:3.30.420.40 10 323 2.3E-91 T 12-10-2018 TL08_19565 222be790f2f93890d3281ee96a8d2a08 542 Pfam PF02543 Carbamoyltransferase N-terminus 2 323 2.8E-56 T 12-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 TL08_25810 efe73e41d5b20489010b25cac3366ac6 409 Gene3D G3DSA:3.40.50.10540 14 403 2.6E-123 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TL08_25810 efe73e41d5b20489010b25cac3366ac6 409 SUPERFAMILY SSF89796 11 409 9.42E-126 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TL08_25810 efe73e41d5b20489010b25cac3366ac6 409 Pfam PF02515 CoA-transferase family III 14 386 5.9E-122 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 TL08_25810 efe73e41d5b20489010b25cac3366ac6 409 Gene3D G3DSA:3.30.1540.10 244 335 2.6E-123 T 12-10-2018 TL08_05400 664c07454e09e313fc2b5f2742ca9c3c 337 Gene3D G3DSA:3.40.50.720 126 303 7.2E-113 T 12-10-2018 TL08_05400 664c07454e09e313fc2b5f2742ca9c3c 337 Pfam PF16884 N-terminal domain of oxidoreductase 6 111 4.6E-37 T 12-10-2018 TL08_05400 664c07454e09e313fc2b5f2742ca9c3c 337 SMART SM00829 18 332 3.7E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_05400 664c07454e09e313fc2b5f2742ca9c3c 337 Gene3D G3DSA:3.90.180.10 20 331 7.2E-113 T 12-10-2018 TL08_05400 664c07454e09e313fc2b5f2742ca9c3c 337 SUPERFAMILY SSF51735 123 299 4.8E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05400 664c07454e09e313fc2b5f2742ca9c3c 337 SUPERFAMILY SSF50129 4 139 1.55E-32 T 12-10-2018 IPR011032 GroES-like superfamily TL08_05400 664c07454e09e313fc2b5f2742ca9c3c 337 Pfam PF00107 Zinc-binding dehydrogenase 158 281 3.4E-17 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_16925 ce8801b56adefc05525b402f8de86462 289 Pfam PF05448 Acetyl xylan esterase (AXE1) 3 233 1.7E-21 T 12-10-2018 IPR008391 Acetyl xylan esterase TL08_16925 ce8801b56adefc05525b402f8de86462 289 SUPERFAMILY SSF53474 4 231 9.96E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16925 ce8801b56adefc05525b402f8de86462 289 Gene3D G3DSA:3.40.50.1820 1 235 9.5E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_01070 3eed2371fcf7f33814cd40ea4982d89a 121 Pfam PF02575 YbaB/EbfC DNA-binding family 6 94 7.0E-34 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_01070 3eed2371fcf7f33814cd40ea4982d89a 121 SUPERFAMILY SSF82607 1 93 1.2E-28 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_01070 3eed2371fcf7f33814cd40ea4982d89a 121 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 93 20.724 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_01070 3eed2371fcf7f33814cd40ea4982d89a 121 Gene3D G3DSA:3.30.1310.10 1 103 2.5E-35 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_01070 3eed2371fcf7f33814cd40ea4982d89a 121 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 87 6.4E-24 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_01070 3eed2371fcf7f33814cd40ea4982d89a 121 PIRSF PIRSF004555 1 114 4.6E-34 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 125 2.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 207 2.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 239 259 2.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 2.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 226 2.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 178 2.1E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 175 203 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 Gene3D G3DSA:3.40.50.720 13 277 3.3E-61 T 12-10-2018 TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 275 3.4E-40 T 12-10-2018 TL08_26565 c5282781e40b44df60742566e1c9d8fd 279 SUPERFAMILY SSF51735 21 275 9.6E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_13495 88e7960c1be414287fb158d1e451cf88 296 Pfam PF03537 Glycoside-hydrolase family GH114 55 283 2.6E-39 T 12-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain TL08_13495 88e7960c1be414287fb158d1e451cf88 296 SUPERFAMILY SSF51445 57 266 1.09E-13 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_17430 a45ff74c474eec5ab2239263a85130d4 395 SUPERFAMILY SSF53822 95 369 4.08E-39 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_17430 a45ff74c474eec5ab2239263a85130d4 395 Pfam PF13407 Periplasmic binding protein domain 128 347 2.2E-26 T 12-10-2018 IPR025997 Periplasmic binding protein TL08_17430 a45ff74c474eec5ab2239263a85130d4 395 Gene3D G3DSA:3.40.50.2300 88 200 2.3E-14 T 12-10-2018 TL08_17430 a45ff74c474eec5ab2239263a85130d4 395 Gene3D G3DSA:3.40.50.2300 201 373 3.8E-23 T 12-10-2018 TL08_09155 3b4011fefe69c119eca4c2bc499f757c 172 Gene3D G3DSA:1.20.1260.10 30 161 7.6E-39 T 12-10-2018 IPR012347 Ferritin-like TL08_09155 3b4011fefe69c119eca4c2bc499f757c 172 SUPERFAMILY SSF47240 31 168 6.49E-33 T 12-10-2018 IPR009078 Ferritin-like superfamily TL08_09155 3b4011fefe69c119eca4c2bc499f757c 172 Pfam PF14530 Domain of unknown function (DUF4439) 36 171 1.3E-35 T 12-10-2018 IPR029447 Domain of unknown function DUF4439 TL08_10535 6e39d83a9e236f5a12906ad0e1da4e4f 265 Gene3D G3DSA:2.40.100.10 106 264 3.4E-45 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TL08_10535 6e39d83a9e236f5a12906ad0e1da4e4f 265 SUPERFAMILY SSF50891 111 261 3.65E-36 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TL08_10535 6e39d83a9e236f5a12906ad0e1da4e4f 265 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 123 138 1.7E-8 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_10535 6e39d83a9e236f5a12906ad0e1da4e4f 265 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 219 234 1.7E-8 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_10535 6e39d83a9e236f5a12906ad0e1da4e4f 265 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 192 207 1.7E-8 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_10535 6e39d83a9e236f5a12906ad0e1da4e4f 265 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 111 261 1.7E-26 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TL08_04455 ae5c114fd5db239d0554707ee8ce78b2 343 SUPERFAMILY SSF102588 15 281 3.14E-60 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_04455 ae5c114fd5db239d0554707ee8ce78b2 343 Gene3D G3DSA:3.40.50.10320 11 296 4.7E-91 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_04455 ae5c114fd5db239d0554707ee8ce78b2 343 Pfam PF02585 GlcNAc-PI de-N-acetylase 17 174 9.2E-25 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TL08_04455 ae5c114fd5db239d0554707ee8ce78b2 343 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 16 296 36.789 T 12-10-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 TL08_04455 ae5c114fd5db239d0554707ee8ce78b2 343 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 17 284 5.8E-89 T 12-10-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 TL08_07655 66f3715aeddac9b83fcfe238f36bc080 362 SUPERFAMILY SSF46785 29 134 1.54E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_07655 66f3715aeddac9b83fcfe238f36bc080 362 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 30 94 2.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_07655 66f3715aeddac9b83fcfe238f36bc080 362 Gene3D G3DSA:1.10.10.10 28 119 2.4E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06960 b4ba998afa07b28f50e65d570826413d 255 Pfam PF00005 ABC transporter 31 173 1.2E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_06960 b4ba998afa07b28f50e65d570826413d 255 SMART SM00382 40 221 0.0018 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_06960 b4ba998afa07b28f50e65d570826413d 255 Gene3D G3DSA:3.40.50.300 4 245 5.7E-55 T 12-10-2018 TL08_06960 b4ba998afa07b28f50e65d570826413d 255 SUPERFAMILY SSF52540 15 232 6.15E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05560 a7b5a6c30418be6724cbfd54db5888f5 193 SUPERFAMILY SSF55729 16 181 2.76E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_05560 a7b5a6c30418be6724cbfd54db5888f5 193 Pfam PF13302 Acetyltransferase (GNAT) domain 17 156 2.4E-17 T 12-10-2018 IPR000182 GNAT domain TL08_05560 a7b5a6c30418be6724cbfd54db5888f5 193 Gene3D G3DSA:3.40.630.30 14 191 5.8E-32 T 12-10-2018 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 Gene3D G3DSA:3.40.50.800 367 462 2.4E-26 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 140 152 8.1E-45 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 320 332 8.1E-45 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 406 425 8.1E-45 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 8.1E-45 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 8.1E-45 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 8.1E-45 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 8.1E-45 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 SUPERFAMILY SSF55681 7 372 4.39E-94 T 12-10-2018 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 155 335 5.6E-8 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 Pfam PF03129 Anticodon binding domain 369 457 6.9E-19 T 12-10-2018 IPR004154 Anticodon-binding TL08_21265 6ab3452f8ef5226abd53e85fab238d46 463 SUPERFAMILY SSF52954 356 461 6.22E-29 T 12-10-2018 TL08_05725 002dc3ba5b4615c07f1792367320855e 286 Pfam PF07366 SnoaL-like polyketide cyclase 5 120 3.1E-14 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 TL08_05725 002dc3ba5b4615c07f1792367320855e 286 Gene3D G3DSA:3.10.450.50 2 133 3.5E-20 T 12-10-2018 TL08_05725 002dc3ba5b4615c07f1792367320855e 286 SUPERFAMILY SSF54427 3 126 9.26E-18 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_12675 c5efea675683b0c66eb5183bb4201db4 126 Gene3D G3DSA:1.10.10.10 6 126 6.1E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12675 c5efea675683b0c66eb5183bb4201db4 126 Pfam PF01638 HxlR-like helix-turn-helix 29 116 1.0E-30 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_12675 c5efea675683b0c66eb5183bb4201db4 126 SUPERFAMILY SSF46785 23 124 9.4E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_04490 633ce30c3f553883bbd4d53fa88e4a38 371 SUPERFAMILY SSF53187 24 370 1.67E-40 T 12-10-2018 TL08_04490 633ce30c3f553883bbd4d53fa88e4a38 371 Gene3D G3DSA:3.40.630.10 31 360 3.8E-94 T 12-10-2018 TL08_04490 633ce30c3f553883bbd4d53fa88e4a38 371 Pfam PF01546 Peptidase family M20/M25/M40 82 370 1.6E-20 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TL08_04490 633ce30c3f553883bbd4d53fa88e4a38 371 SUPERFAMILY SSF55031 186 286 2.39E-19 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TL08_04490 633ce30c3f553883bbd4d53fa88e4a38 371 Pfam PF07687 Peptidase dimerisation domain 186 283 1.4E-12 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TL08_04490 633ce30c3f553883bbd4d53fa88e4a38 371 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 22 371 7.8E-155 T 12-10-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 TL08_04490 633ce30c3f553883bbd4d53fa88e4a38 371 Gene3D G3DSA:3.30.70.360 186 294 3.8E-94 T 12-10-2018 TL08_25880 71ea289beeccfb9473f23295254dad9d 284 SUPERFAMILY SSF47413 9 69 2.7E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_25880 71ea289beeccfb9473f23295254dad9d 284 SMART SM00530 15 70 2.5E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_25880 71ea289beeccfb9473f23295254dad9d 284 Gene3D G3DSA:1.10.260.40 7 73 1.4E-8 T 12-10-2018 TL08_25880 71ea289beeccfb9473f23295254dad9d 284 Pfam PF13560 Helix-turn-helix domain 12 73 3.9E-14 T 12-10-2018 TL08_01100 05f39ccad8f886c7ebf0aab0d2c0ccc2 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 317 2.7E-20 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_01100 05f39ccad8f886c7ebf0aab0d2c0ccc2 331 Pfam PF00005 ABC transporter 25 182 2.0E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_01100 05f39ccad8f886c7ebf0aab0d2c0ccc2 331 SMART SM00382 33 231 4.8E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_01100 05f39ccad8f886c7ebf0aab0d2c0ccc2 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 9.7E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_01100 05f39ccad8f886c7ebf0aab0d2c0ccc2 331 SUPERFAMILY SSF52540 3 253 1.14E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01100 05f39ccad8f886c7ebf0aab0d2c0ccc2 331 Gene3D G3DSA:3.40.50.300 1 329 5.9E-93 T 12-10-2018 TL08_25270 b3e3c7480e4d39a584dadfca08b22482 118 Pfam PF02597 ThiS family 40 118 5.7E-9 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TL08_25270 b3e3c7480e4d39a584dadfca08b22482 118 SUPERFAMILY SSF54285 38 116 1.39E-11 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TL08_25270 b3e3c7480e4d39a584dadfca08b22482 118 Gene3D G3DSA:3.10.20.30 38 118 9.3E-17 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TL08_24385 558087844773b0b47f409365a8b36840 362 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 351 2.8E-73 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 TL08_24385 558087844773b0b47f409365a8b36840 362 SUPERFAMILY SSF51556 6 352 1.74E-69 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_24385 558087844773b0b47f409365a8b36840 362 Gene3D G3DSA:3.20.20.140 2 360 3.7E-99 T 12-10-2018 TL08_24385 558087844773b0b47f409365a8b36840 362 Hamap MF_00540 Adenosine deaminase [add]. 8 353 50.18 T 12-10-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 TL08_24385 558087844773b0b47f409365a8b36840 362 Pfam PF00962 Adenosine/AMP deaminase 13 350 1.3E-80 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 TL08_05715 8a57ecf3df8c7e103efc6f8cedd6bcf2 300 SUPERFAMILY SSF55048 124 185 1.05E-7 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TL08_05715 8a57ecf3df8c7e103efc6f8cedd6bcf2 300 Pfam PF00698 Acyl transferase domain 4 257 2.4E-39 T 12-10-2018 IPR014043 Acyl transferase TL08_05715 8a57ecf3df8c7e103efc6f8cedd6bcf2 300 SUPERFAMILY SSF52151 1 280 1.28E-59 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TL08_05715 8a57ecf3df8c7e103efc6f8cedd6bcf2 300 Gene3D G3DSA:3.40.366.10 3 276 1.5E-78 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TL08_05715 8a57ecf3df8c7e103efc6f8cedd6bcf2 300 Gene3D G3DSA:3.30.70.250 122 190 1.5E-78 T 12-10-2018 TL08_05715 8a57ecf3df8c7e103efc6f8cedd6bcf2 300 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 294 1.4E-24 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TL08_05715 8a57ecf3df8c7e103efc6f8cedd6bcf2 300 PIRSF PIRSF000446 1 292 1.4E-65 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TL08_09350 3e861d3b7c115265f438367ec3c04d54 792 SUPERFAMILY SSF46785 712 777 2.04E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_09350 3e861d3b7c115265f438367ec3c04d54 792 Pfam PF01580 FtsK/SpoIIIE family 421 610 2.8E-59 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TL08_09350 3e861d3b7c115265f438367ec3c04d54 792 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 52 178 8.8E-11 T 12-10-2018 IPR025199 DNA translocase FtsK, 4TM region TL08_09350 3e861d3b7c115265f438367ec3c04d54 792 SUPERFAMILY SSF52540 384 681 3.39E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09350 3e861d3b7c115265f438367ec3c04d54 792 SMART SM00843 711 775 1.2E-27 T 12-10-2018 IPR018541 FtsK gamma domain TL08_09350 3e861d3b7c115265f438367ec3c04d54 792 Pfam PF09397 Ftsk gamma domain 716 772 7.0E-21 T 12-10-2018 IPR018541 FtsK gamma domain TL08_09350 3e861d3b7c115265f438367ec3c04d54 792 Gene3D G3DSA:3.40.50.300 407 696 6.5E-103 T 12-10-2018 TL08_09350 3e861d3b7c115265f438367ec3c04d54 792 Gene3D G3DSA:3.30.980.40 304 406 8.1E-30 T 12-10-2018 TL08_09350 3e861d3b7c115265f438367ec3c04d54 792 Gene3D G3DSA:1.10.10.10 715 776 6.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16070 e32aefcc6eec357f4147d40ea0bd480c 276 Pfam PF01061 ABC-2 type transporter 38 226 3.8E-11 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_05250 5a632b5aa87e3dc747c5c989c5672244 153 SUPERFAMILY SSF46785 11 146 5.55E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05250 5a632b5aa87e3dc747c5c989c5672244 153 SMART SM00347 30 137 2.0E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_05250 5a632b5aa87e3dc747c5c989c5672244 153 Pfam PF01047 MarR family 37 95 1.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_05250 5a632b5aa87e3dc747c5c989c5672244 153 Gene3D G3DSA:1.10.10.10 3 151 5.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 SUPERFAMILY SSF48264 16 399 2.49E-73 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 Gene3D G3DSA:1.10.630.10 9 399 3.9E-99 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 PRINTS PR00359 B-class P450 signature 196 218 4.9E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 PRINTS PR00359 B-class P450 signature 272 283 4.9E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 PRINTS PR00359 B-class P450 signature 160 175 4.9E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 PRINTS PR00359 B-class P450 signature 290 317 4.9E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 PRINTS PR00359 B-class P450 signature 318 333 4.9E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 PRINTS PR00359 B-class P450 signature 143 159 4.9E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 PRINTS PR00359 B-class P450 signature 348 359 4.9E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 PRINTS PR00359 B-class P450 signature 339 348 4.9E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_20005 5cc01a847680fbaa58b3abddf03c1e1d 399 Pfam PF00067 Cytochrome P450 261 369 1.6E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_08400 94f14f19491a9b36d0a36ba57dc09f82 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 1.2E-44 T 12-10-2018 IPR025242 Protein of unknown function DUF4193 TL08_18675 0810c226ac443f07a74f60d855c3678e 205 Pfam PF04542 Sigma-70 region 2 29 96 2.1E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_18675 0810c226ac443f07a74f60d855c3678e 205 Pfam PF04545 Sigma-70, region 4 135 184 1.2E-13 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TL08_18675 0810c226ac443f07a74f60d855c3678e 205 Gene3D G3DSA:1.10.10.10 92 187 3.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18675 0810c226ac443f07a74f60d855c3678e 205 Gene3D G3DSA:1.10.1740.10 11 91 2.5E-28 T 12-10-2018 TL08_18675 0810c226ac443f07a74f60d855c3678e 205 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 186 1.8E-29 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_18675 0810c226ac443f07a74f60d855c3678e 205 SUPERFAMILY SSF88946 5 108 8.48E-27 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_18675 0810c226ac443f07a74f60d855c3678e 205 SUPERFAMILY SSF88659 127 186 2.24E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 1.2E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 1.2E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.2E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.2E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 SUPERFAMILY SSF51735 1 145 3.11E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 SUPERFAMILY SSF116726 134 214 2.35E-14 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 Pfam PF02080 TrkA-C domain 149 214 4.4E-14 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 Gene3D G3DSA:3.40.50.720 2 133 2.1E-29 T 12-10-2018 TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 Pfam PF02254 TrkA-N domain 3 118 8.9E-25 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TL08_08430 00b0a763357073bc7b6cd963d6268f85 225 Gene3D G3DSA:3.30.70.1450 136 217 1.9E-17 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TL08_05680 87fb12bdd54bbba4267c85a828fd32cb 100 Pfam PF00550 Phosphopantetheine attachment site 19 86 1.9E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_05680 87fb12bdd54bbba4267c85a828fd32cb 100 Gene3D G3DSA:1.10.1200.10 15 96 5.7E-19 T 12-10-2018 IPR036736 ACP-like superfamily TL08_05680 87fb12bdd54bbba4267c85a828fd32cb 100 SUPERFAMILY SSF47336 18 90 2.62E-13 T 12-10-2018 IPR036736 ACP-like superfamily TL08_22150 eebb652421fdcc96938e0cf62fa36a3a 139 Pfam PF11253 Protein of unknown function (DUF3052) 13 136 3.5E-59 T 12-10-2018 IPR021412 Protein of unknown function DUF3052 TL08_05665 33438e16beef8b5e33998401b0b8f977 291 Pfam PF13023 HD domain 102 249 4.2E-28 T 12-10-2018 IPR006674 HD domain TL08_05665 33438e16beef8b5e33998401b0b8f977 291 Gene3D G3DSA:1.10.3210.10 87 270 1.5E-49 T 12-10-2018 TL08_05665 33438e16beef8b5e33998401b0b8f977 291 SMART SM00345 16 75 1.7E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_05665 33438e16beef8b5e33998401b0b8f977 291 SUPERFAMILY SSF109604 96 239 1.19E-32 T 12-10-2018 TL08_05665 33438e16beef8b5e33998401b0b8f977 291 Gene3D G3DSA:1.10.10.10 3 77 2.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05665 33438e16beef8b5e33998401b0b8f977 291 SUPERFAMILY SSF46785 5 79 1.85E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05665 33438e16beef8b5e33998401b0b8f977 291 SMART SM00471 119 233 1.4E-8 T 12-10-2018 IPR003607 HD/PDEase domain TL08_05665 33438e16beef8b5e33998401b0b8f977 291 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 1.6E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_24120 146c27d74c7646b13a872a22020a5b41 327 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 10 321 1.2E-107 T 12-10-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV-5884 family TL08_24120 146c27d74c7646b13a872a22020a5b41 327 SUPERFAMILY SSF56059 140 311 2.43E-14 T 12-10-2018 TL08_24120 146c27d74c7646b13a872a22020a5b41 327 Gene3D G3DSA:3.30.470.20 216 323 4.7E-13 T 12-10-2018 TL08_01365 2ef04242c21b0ed345a45dbdc63e3d8e 153 Pfam PF00472 RF-1 domain 23 148 1.2E-24 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TL08_01365 2ef04242c21b0ed345a45dbdc63e3d8e 153 Gene3D G3DSA:3.30.160.20 17 153 2.0E-32 T 12-10-2018 TL08_01365 2ef04242c21b0ed345a45dbdc63e3d8e 153 SUPERFAMILY SSF75620 24 133 1.14E-11 T 12-10-2018 TL08_26265 f5f73d68e7fb045b9e2818bf23e854ac 237 Pfam PF02390 Putative methyltransferase 59 226 3.9E-50 T 12-10-2018 TL08_26265 f5f73d68e7fb045b9e2818bf23e854ac 237 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 55 225 4.4E-40 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 TL08_26265 f5f73d68e7fb045b9e2818bf23e854ac 237 SUPERFAMILY SSF53335 7 235 1.49E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_26265 f5f73d68e7fb045b9e2818bf23e854ac 237 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 17 236 28.684 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 TL08_26265 f5f73d68e7fb045b9e2818bf23e854ac 237 Gene3D G3DSA:3.40.50.150 23 237 7.0E-63 T 12-10-2018 TL08_23100 766b85d637cdd32e5b519305be49a94e 304 Gene3D G3DSA:3.40.190.10 47 301 1.8E-62 T 12-10-2018 TL08_23100 766b85d637cdd32e5b519305be49a94e 304 Gene3D G3DSA:3.40.190.120 144 247 1.8E-62 T 12-10-2018 TL08_23100 766b85d637cdd32e5b519305be49a94e 304 SUPERFAMILY SSF53850 45 302 8.14E-40 T 12-10-2018 TL08_23100 766b85d637cdd32e5b519305be49a94e 304 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 45 302 1.3E-35 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 TL08_02610 50e95adff20388f1457abf936e9b1588 183 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 1.1E-24 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02610 50e95adff20388f1457abf936e9b1588 183 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 151 3.3E-70 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02610 50e95adff20388f1457abf936e9b1588 183 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02610 50e95adff20388f1457abf936e9b1588 183 SUPERFAMILY SSF56770 9 153 3.66E-66 T 12-10-2018 TL08_02610 50e95adff20388f1457abf936e9b1588 183 Gene3D G3DSA:3.40.50.12280 2 169 6.0E-74 T 12-10-2018 TL08_02610 50e95adff20388f1457abf936e9b1588 183 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 43.137 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_05235 a4c23822d58642528ff82e259c4e9c01 133 Pfam PF12680 SnoaL-like domain 24 113 1.5E-11 T 12-10-2018 IPR037401 SnoaL-like domain TL08_05235 a4c23822d58642528ff82e259c4e9c01 133 Gene3D G3DSA:3.10.450.50 10 133 6.8E-31 T 12-10-2018 TL08_05235 a4c23822d58642528ff82e259c4e9c01 133 SUPERFAMILY SSF54427 15 122 2.34E-22 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_10940 88f9434955132aa622a917b92cf1fd35 158 Pfam PF02566 OsmC-like protein 51 148 7.5E-14 T 12-10-2018 IPR003718 OsmC/Ohr family TL08_10940 88f9434955132aa622a917b92cf1fd35 158 SUPERFAMILY SSF82784 4 151 7.46E-44 T 12-10-2018 IPR036102 OsmC/Ohr superfamily TL08_10940 88f9434955132aa622a917b92cf1fd35 158 Gene3D G3DSA:3.30.300.20 1 150 4.2E-52 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_03145 c438a30f0c13890f071ad1fde283fac5 241 Pfam PF01416 tRNA pseudouridine synthase 120 221 4.0E-23 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_03145 c438a30f0c13890f071ad1fde283fac5 241 Gene3D G3DSA:3.30.70.660 81 219 2.6E-34 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 TL08_03145 c438a30f0c13890f071ad1fde283fac5 241 SUPERFAMILY SSF55120 1 226 4.89E-58 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_03145 c438a30f0c13890f071ad1fde283fac5 241 Gene3D G3DSA:3.30.70.580 1 80 2.6E-19 T 12-10-2018 TL08_03145 c438a30f0c13890f071ad1fde283fac5 241 PIRSF PIRSF001430 1 237 7.4E-55 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 216 1.3E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 2.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 2.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 2.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 SUPERFAMILY SSF46894 143 218 1.05E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 SMART SM00421 159 216 1.6E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 SUPERFAMILY SSF52172 4 139 5.55E-30 T 12-10-2018 IPR011006 CheY-like superfamily TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 Pfam PF00072 Response regulator receiver domain 7 123 9.8E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 Gene3D G3DSA:3.40.50.12740 5 220 3.8E-61 T 12-10-2018 TL08_18460 35fa59fc172bd8442c6f8a6640aacff6 221 SMART SM00448 5 122 7.0E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_03060 944cfac275f0de1aca24336ee6355690 179 Gene3D G3DSA:3.90.930.12 1 83 1.9E-29 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03060 944cfac275f0de1aca24336ee6355690 179 Gene3D G3DSA:3.90.930.12 84 179 1.2E-39 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03060 944cfac275f0de1aca24336ee6355690 179 Pfam PF00347 Ribosomal protein L6 92 165 6.5E-20 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03060 944cfac275f0de1aca24336ee6355690 179 Pfam PF00347 Ribosomal protein L6 11 83 4.0E-18 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03060 944cfac275f0de1aca24336ee6355690 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03060 944cfac275f0de1aca24336ee6355690 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.88 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TL08_03060 944cfac275f0de1aca24336ee6355690 179 SUPERFAMILY SSF56053 84 178 2.22E-35 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03060 944cfac275f0de1aca24336ee6355690 179 PIRSF PIRSF002162 1 178 4.3E-45 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03060 944cfac275f0de1aca24336ee6355690 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.4E-33 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TL08_03060 944cfac275f0de1aca24336ee6355690 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.4E-33 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TL08_03060 944cfac275f0de1aca24336ee6355690 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.4E-33 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TL08_03060 944cfac275f0de1aca24336ee6355690 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.6E-73 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TL08_03060 944cfac275f0de1aca24336ee6355690 179 SUPERFAMILY SSF56053 1 83 4.71E-26 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_19025 56668d73d1433b6b444b3c1e0f146f4f 384 SUPERFAMILY SSF52540 74 290 6.37E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19025 56668d73d1433b6b444b3c1e0f146f4f 384 SMART SM00382 91 247 1.5E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_19025 56668d73d1433b6b444b3c1e0f146f4f 384 Pfam PF07728 AAA domain (dynein-related subfamily) 95 237 1.8E-35 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TL08_19025 56668d73d1433b6b444b3c1e0f146f4f 384 Gene3D G3DSA:3.40.50.300 75 247 1.1E-23 T 12-10-2018 TL08_04990 0ce637e1a4c49738ac9d1b3eb4ff72cc 299 Gene3D G3DSA:3.20.20.30 13 296 1.1E-35 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_04990 0ce637e1a4c49738ac9d1b3eb4ff72cc 299 Pfam PF00296 Luciferase-like monooxygenase 11 272 4.8E-22 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_04990 0ce637e1a4c49738ac9d1b3eb4ff72cc 299 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 12 297 3.0E-100 T 12-10-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted TL08_04990 0ce637e1a4c49738ac9d1b3eb4ff72cc 299 SUPERFAMILY SSF51679 13 292 2.65E-41 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_21590 64d7b6675a136bc057ab8e4bcd698f5a 371 SUPERFAMILY SSF55315 255 370 7.65E-6 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_21590 64d7b6675a136bc057ab8e4bcd698f5a 371 SUPERFAMILY SSF53137 117 210 7.32E-5 T 12-10-2018 TL08_10440 af9d6222bbf30d1357f7ccd54c1f27aa 151 Pfam PF08592 Domain of unknown function (DUF1772) 19 143 7.5E-16 T 12-10-2018 TL08_20595 98a0f2f1ef11c3dad75cc3d9dc3595a4 433 SMART SM00341 253 333 1.9E-18 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TL08_20595 98a0f2f1ef11c3dad75cc3d9dc3595a4 433 Gene3D G3DSA:1.10.150.80 342 432 2.1E-28 T 12-10-2018 TL08_20595 98a0f2f1ef11c3dad75cc3d9dc3595a4 433 SUPERFAMILY SSF47819 234 340 5.45E-23 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TL08_20595 98a0f2f1ef11c3dad75cc3d9dc3595a4 433 Gene3D G3DSA:1.10.150.80 238 335 2.0E-25 T 12-10-2018 TL08_20595 98a0f2f1ef11c3dad75cc3d9dc3595a4 433 Pfam PF00570 HRDC domain 258 322 3.1E-13 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 TL08_20595 98a0f2f1ef11c3dad75cc3d9dc3595a4 433 SUPERFAMILY SSF53098 36 251 2.2E-51 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_20595 98a0f2f1ef11c3dad75cc3d9dc3595a4 433 Gene3D G3DSA:3.30.420.10 31 235 4.3E-69 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_20595 98a0f2f1ef11c3dad75cc3d9dc3595a4 433 Pfam PF01612 3'-5' exonuclease 50 213 1.9E-29 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TL08_20595 98a0f2f1ef11c3dad75cc3d9dc3595a4 433 SMART SM00474 47 214 6.8E-33 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TL08_26065 b0bb0ee5634f6e8eb317baa6a472823a 457 SUPERFAMILY SSF140459 19 172 2.33E-6 T 12-10-2018 TL08_26065 b0bb0ee5634f6e8eb317baa6a472823a 457 PRINTS PR01217 Proline rich extensin signature 251 267 8.0E-14 T 12-10-2018 TL08_26065 b0bb0ee5634f6e8eb317baa6a472823a 457 PRINTS PR01217 Proline rich extensin signature 277 294 8.0E-14 T 12-10-2018 TL08_26065 b0bb0ee5634f6e8eb317baa6a472823a 457 PRINTS PR01217 Proline rich extensin signature 208 220 8.0E-14 T 12-10-2018 TL08_26065 b0bb0ee5634f6e8eb317baa6a472823a 457 PRINTS PR01217 Proline rich extensin signature 295 320 8.0E-14 T 12-10-2018 TL08_26065 b0bb0ee5634f6e8eb317baa6a472823a 457 PRINTS PR01217 Proline rich extensin signature 169 185 8.0E-14 T 12-10-2018 TL08_26065 b0bb0ee5634f6e8eb317baa6a472823a 457 PRINTS PR01217 Proline rich extensin signature 229 250 8.0E-14 T 12-10-2018 TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.8E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 7.8E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 7.8E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 SUPERFAMILY SSF51735 5 250 4.47E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 Gene3D G3DSA:3.40.50.720 1 255 2.0E-80 T 12-10-2018 TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 248 5.7E-63 T 12-10-2018 TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_03560 417b69f9f48334c856779ae2e4fbe650 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_01710 b3b533397a34f46e1c4ed4382efe8488 305 Gene3D G3DSA:1.10.1040.20 184 283 2.6E-14 T 12-10-2018 IPR037108 TM1727-like, C-terminal domain superfamily TL08_01710 b3b533397a34f46e1c4ed4382efe8488 305 SUPERFAMILY SSF48179 185 284 1.46E-23 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_01710 b3b533397a34f46e1c4ed4382efe8488 305 Pfam PF10727 Rossmann-like domain 7 128 3.8E-48 T 12-10-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain TL08_01710 b3b533397a34f46e1c4ed4382efe8488 305 SUPERFAMILY SSF51735 14 182 2.08E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_01710 b3b533397a34f46e1c4ed4382efe8488 305 Gene3D G3DSA:3.40.50.720 11 182 7.3E-32 T 12-10-2018 TL08_01710 b3b533397a34f46e1c4ed4382efe8488 305 Pfam PF10728 Domain of unknown function (DUF2520) 160 278 5.6E-35 T 12-10-2018 IPR018931 Domain of unknown function DUF2520 TL08_27145 657dc07043a6f8834335dd0eceba3690 102 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 15 83 24.341 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TL08_27145 657dc07043a6f8834335dd0eceba3690 102 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 30 82 2.0E-18 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TL08_27145 657dc07043a6f8834335dd0eceba3690 102 Pfam PF01809 Haemolytic domain 17 82 4.9E-28 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TL08_27145 657dc07043a6f8834335dd0eceba3690 102 SMART SM01234 15 82 1.4E-42 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TL08_27145 657dc07043a6f8834335dd0eceba3690 102 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 21 90 2.6E-27 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 SUPERFAMILY SSF54814 180 258 1.96E-26 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 Pfam PF08529 NusA N-terminal domain 6 60 9.7E-9 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 Pfam PF08529 NusA N-terminal domain 68 100 1.2E-6 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 Gene3D G3DSA:3.30.1480.10 1 99 2.2E-34 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 Gene3D G3DSA:3.30.300.20 179 257 3.0E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 SUPERFAMILY SSF50249 110 179 3.22E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 323 2.2E-105 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 Gene3D G3DSA:2.40.50.140 105 178 6.4E-29 T 12-10-2018 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 Gene3D G3DSA:3.30.300.20 258 329 1.3E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 341 26.008 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 SUPERFAMILY SSF69705 4 99 1.11E-30 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 SUPERFAMILY SSF54814 259 323 5.17E-17 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 SMART SM00316 110 180 5.4E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 TL08_09170 ec89820abe62a0ddb223ffbca5810b0f 349 Pfam PF13184 NusA-like KH domain 211 278 6.4E-24 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 TL08_24795 aa213e0206a866c942185641d6738be1 411 Gene3D G3DSA:3.40.50.280 287 399 6.1E-8 T 12-10-2018 TL08_24795 aa213e0206a866c942185641d6738be1 411 SMART SM00422 37 106 6.4E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24795 aa213e0206a866c942185641d6738be1 411 SUPERFAMILY SSF46955 38 104 1.01E-11 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_24795 aa213e0206a866c942185641d6738be1 411 Gene3D G3DSA:1.10.1660.10 31 106 1.9E-18 T 12-10-2018 TL08_24795 aa213e0206a866c942185641d6738be1 411 Pfam PF13411 MerR HTH family regulatory protein 38 102 9.7E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_22875 a797411328be9bedb29af3790f5ce5e4 361 Gene3D G3DSA:2.40.290.10 1 177 7.9E-15 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily TL08_22875 a797411328be9bedb29af3790f5ce5e4 361 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 252 4.8E-89 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type TL08_22875 a797411328be9bedb29af3790f5ce5e4 361 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 250 32.462 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type TL08_22875 a797411328be9bedb29af3790f5ce5e4 361 SMART SM00559 49 177 3.4E-34 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 TL08_22875 a797411328be9bedb29af3790f5ce5e4 361 SUPERFAMILY SSF100939 1 251 4.12E-52 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily TL08_22875 a797411328be9bedb29af3790f5ce5e4 361 Pfam PF02735 Ku70/Ku80 beta-barrel domain 8 184 5.1E-36 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 TL08_25075 42718806ccd2952c4ef19825e77ce870 335 SUPERFAMILY SSF51735 124 300 7.89E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_25075 42718806ccd2952c4ef19825e77ce870 335 SUPERFAMILY SSF50129 6 143 2.04E-38 T 12-10-2018 IPR011032 GroES-like superfamily TL08_25075 42718806ccd2952c4ef19825e77ce870 335 Gene3D G3DSA:3.40.50.720 127 304 3.0E-131 T 12-10-2018 TL08_25075 42718806ccd2952c4ef19825e77ce870 335 Pfam PF00107 Zinc-binding dehydrogenase 159 287 1.8E-23 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_25075 42718806ccd2952c4ef19825e77ce870 335 Pfam PF16884 N-terminal domain of oxidoreductase 7 112 1.4E-36 T 12-10-2018 TL08_25075 42718806ccd2952c4ef19825e77ce870 335 SMART SM00829 20 333 3.8E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_25075 42718806ccd2952c4ef19825e77ce870 335 Gene3D G3DSA:3.90.180.10 21 332 3.0E-131 T 12-10-2018 TL08_09120 39f0f0fc3845f69c313617e3864496b4 438 Gene3D G3DSA:3.40.630.30 7 139 1.1E-28 T 12-10-2018 TL08_09120 39f0f0fc3845f69c313617e3864496b4 438 Pfam PF13530 Sterol carrier protein domain 242 432 4.1E-32 T 12-10-2018 IPR025559 Enhanced intracellular survival protein domain TL08_09120 39f0f0fc3845f69c313617e3864496b4 438 Gene3D G3DSA:3.30.1050.10 338 428 3.6E-20 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TL08_09120 39f0f0fc3845f69c313617e3864496b4 438 SUPERFAMILY SSF55718 333 438 2.63E-19 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TL08_09120 39f0f0fc3845f69c313617e3864496b4 438 Pfam PF13527 Acetyltransferase (GNAT) domain 14 136 1.5E-20 T 12-10-2018 TL08_09120 39f0f0fc3845f69c313617e3864496b4 438 SUPERFAMILY SSF55729 14 189 5.03E-32 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_09120 39f0f0fc3845f69c313617e3864496b4 438 SUPERFAMILY SSF55729 242 332 1.94E-7 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_14670 2f46b7031b3a03d68c7ff2a84fcfb37d 210 SUPERFAMILY SSF46689 21 85 4.05E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14670 2f46b7031b3a03d68c7ff2a84fcfb37d 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 5.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14670 2f46b7031b3a03d68c7ff2a84fcfb37d 210 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 96 193 2.6E-10 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal TL08_14670 2f46b7031b3a03d68c7ff2a84fcfb37d 210 Gene3D G3DSA:1.10.357.10 15 207 9.4E-28 T 12-10-2018 TL08_14670 2f46b7031b3a03d68c7ff2a84fcfb37d 210 SUPERFAMILY SSF48498 94 199 1.38E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_22600 e44f266c9d7b36f5d9eb8283d8945cb7 222 SUPERFAMILY SSF50475 11 194 2.75E-53 T 12-10-2018 TL08_22600 e44f266c9d7b36f5d9eb8283d8945cb7 222 Gene3D G3DSA:2.30.110.10 11 222 3.0E-67 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_22600 e44f266c9d7b36f5d9eb8283d8945cb7 222 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 30 171 6.0E-42 T 12-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related TL08_03050 d8ff6a3e341c6bb53166f0d9653dab71 61 Gene3D G3DSA:4.10.830.10 1 61 3.8E-31 T 12-10-2018 TL08_03050 d8ff6a3e341c6bb53166f0d9653dab71 61 SUPERFAMILY SSF57716 4 61 7.84E-22 T 12-10-2018 TL08_03050 d8ff6a3e341c6bb53166f0d9653dab71 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.163 T 12-10-2018 IPR023053 Ribosomal protein S14, type Z TL08_03050 d8ff6a3e341c6bb53166f0d9653dab71 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 2.3E-24 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03050 d8ff6a3e341c6bb53166f0d9653dab71 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 12-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_09760 9b8384ad5fc9fd3dcef5c301e6b51b56 215 Gene3D G3DSA:1.10.357.10 77 203 1.1E-33 T 12-10-2018 TL08_09760 9b8384ad5fc9fd3dcef5c301e6b51b56 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 2.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_09760 9b8384ad5fc9fd3dcef5c301e6b51b56 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 2.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_09760 9b8384ad5fc9fd3dcef5c301e6b51b56 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 4.0E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_09760 9b8384ad5fc9fd3dcef5c301e6b51b56 215 SUPERFAMILY SSF46689 15 79 1.08E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_09760 9b8384ad5fc9fd3dcef5c301e6b51b56 215 Gene3D G3DSA:1.10.10.60 14 76 1.6E-21 T 12-10-2018 TL08_09760 9b8384ad5fc9fd3dcef5c301e6b51b56 215 SUPERFAMILY SSF48498 97 202 9.78E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_06660 833f1bf99f0a689ebefb96aea89605fd 136 Gene3D G3DSA:2.30.110.10 1 135 3.0E-29 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_06660 833f1bf99f0a689ebefb96aea89605fd 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 88 1.5E-15 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_06660 833f1bf99f0a689ebefb96aea89605fd 136 SUPERFAMILY SSF50475 5 134 1.13E-26 T 12-10-2018 TL08_06660 833f1bf99f0a689ebefb96aea89605fd 136 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 8 134 1.2E-32 T 12-10-2018 IPR019920 F420-binding domain, putative TL08_03365 eb895e095cc3cbf0ac4a81c28ed9c33a 226 Pfam PF11139 Sap, sulfolipid-1-addressing protein 9 211 3.3E-24 T 12-10-2018 IPR021315 Glycolipid exporter Gap/Sap TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 Gene3D G3DSA:1.25.40.10 577 828 3.6E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 Gene3D G3DSA:1.25.40.10 85 252 4.6E-45 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SUPERFAMILY SSF52540 255 525 3.43E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 PRINTS PR00364 Disease resistance protein signature 291 306 1.3E-9 T 12-10-2018 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 PRINTS PR00364 Disease resistance protein signature 372 386 1.3E-9 T 12-10-2018 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 PRINTS PR00364 Disease resistance protein signature 457 471 1.3E-9 T 12-10-2018 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 Pfam PF00486 Transcriptional regulatory protein, C terminal 13 81 1.1E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SUPERFAMILY SSF48452 83 236 5.06E-33 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SMART SM00862 5 81 1.2E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SUPERFAMILY SSF46894 6 81 1.25E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 Pfam PF00931 NB-ARC domain 289 531 4.1E-15 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 Gene3D G3DSA:1.25.40.10 829 916 7.5E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 Gene3D G3DSA:1.10.10.10 1 83 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 Pfam PF03704 Bacterial transcriptional activator domain 88 233 5.3E-41 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 Gene3D G3DSA:3.40.50.300 253 411 5.2E-26 T 12-10-2018 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SMART SM01043 88 233 9.1E-50 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SMART SM00028 791 824 19.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SMART SM00028 711 744 5.2E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SMART SM00028 751 784 3.4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SMART SM00028 871 904 13.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SMART SM00028 93 126 230.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SMART SM00028 183 216 280.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 SUPERFAMILY SSF48452 697 906 4.93E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15220 5130240fe39b8f9fce8b615f1e5beb57 924 Pfam PF13424 Tetratricopeptide repeat 751 820 1.8E-11 T 12-10-2018 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 PRINTS PR01100 Shikimate kinase family signature 77 86 2.9E-17 T 12-10-2018 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 PRINTS PR01100 Shikimate kinase family signature 97 114 2.9E-17 T 12-10-2018 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 PRINTS PR01100 Shikimate kinase family signature 7 22 2.9E-17 T 12-10-2018 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 PRINTS PR01100 Shikimate kinase family signature 59 67 2.9E-17 T 12-10-2018 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 PRINTS PR01100 Shikimate kinase family signature 31 44 2.9E-17 T 12-10-2018 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 Pfam PF01202 Shikimate kinase 13 168 1.8E-40 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 SUPERFAMILY SSF52540 7 165 6.9E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 Gene3D G3DSA:3.40.50.300 4 178 1.1E-50 T 12-10-2018 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 Hamap MF_00109 Shikimate kinase [aroK]. 4 169 26.858 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TL08_11420 69a7055381a52528ff9e24a3f7f6b004 191 SMART SM00382 3 141 3.9E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_00565 a478a48e59efa7a289e2226aa135c723 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 4 204 8.0E-65 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TL08_00565 a478a48e59efa7a289e2226aa135c723 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 3.7E-98 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TL08_00565 a478a48e59efa7a289e2226aa135c723 335 PIRSF PIRSF000267 1 331 3.0E-105 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TL08_23625 05c16d0c3552601f02cc22704f6fd7f9 81 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 16 74 3.1E-19 T 12-10-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit TL08_25615 56c67c93b7c68c9abc21f10f58bf1b99 300 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 63 230 1.3E-51 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TL08_25615 56c67c93b7c68c9abc21f10f58bf1b99 300 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 59 234 6.2E-34 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TL08_09665 af20a57bab8abfbedfe299d2909795a3 106 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 3 105 3.3E-10 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 TL08_09665 af20a57bab8abfbedfe299d2909795a3 106 Gene3D G3DSA:3.10.450.50 1 106 7.0E-22 T 12-10-2018 TL08_09665 af20a57bab8abfbedfe299d2909795a3 106 SUPERFAMILY SSF54427 3 104 6.46E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_09885 8419b230a2b85aaf0a6ad3105331dea9 315 Pfam PF00149 Calcineurin-like phosphoesterase 40 240 6.5E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_09885 8419b230a2b85aaf0a6ad3105331dea9 315 Gene3D G3DSA:3.60.21.10 40 259 1.5E-16 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_09885 8419b230a2b85aaf0a6ad3105331dea9 315 SUPERFAMILY SSF56300 40 258 9.22E-29 T 12-10-2018 TL08_10795 fe0d49f96a04b97aed6b2348185ae1a7 165 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 29 4.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10795 fe0d49f96a04b97aed6b2348185ae1a7 165 Gene3D G3DSA:1.10.357.10 1 162 5.5E-42 T 12-10-2018 TL08_10795 fe0d49f96a04b97aed6b2348185ae1a7 165 SUPERFAMILY SSF48498 45 155 3.5E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_10795 fe0d49f96a04b97aed6b2348185ae1a7 165 SUPERFAMILY SSF46689 2 42 2.77E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_19930 2d622b86e8dd2d072ad4e1aaf58dd93a 292 SUPERFAMILY SSF161098 25 292 1.44E-58 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19930 2d622b86e8dd2d072ad4e1aaf58dd93a 292 Gene3D G3DSA:1.10.3720.10 20 280 9.0E-47 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19930 2d622b86e8dd2d072ad4e1aaf58dd93a 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 286 1.2E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_09645 4aa57481e0fbf86aa55368b5c3165305 352 Gene3D G3DSA:3.40.50.10800 119 344 4.8E-109 T 12-10-2018 TL08_09645 4aa57481e0fbf86aa55368b5c3165305 352 SUPERFAMILY SSF142754 37 345 1.44E-100 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TL08_09645 4aa57481e0fbf86aa55368b5c3165305 352 Pfam PF02445 Quinolinate synthetase A protein 39 344 4.1E-110 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TL08_09645 4aa57481e0fbf86aa55368b5c3165305 352 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 37 345 4.9E-88 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TL08_09645 4aa57481e0fbf86aa55368b5c3165305 352 Gene3D G3DSA:3.40.50.10800 39 326 4.8E-109 T 12-10-2018 TL08_09645 4aa57481e0fbf86aa55368b5c3165305 352 Gene3D G3DSA:3.40.50.10800 204 301 4.8E-109 T 12-10-2018 TL08_11180 1676ceb2c408173e39969aed50581a82 103 Gene3D G3DSA:3.30.70.100 1 94 4.8E-15 T 12-10-2018 TL08_11180 1676ceb2c408173e39969aed50581a82 103 Pfam PF05336 L-rhamnose mutarotase 4 90 1.9E-16 T 12-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 TL08_11180 1676ceb2c408173e39969aed50581a82 103 SUPERFAMILY SSF54909 1 102 5.72E-22 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_12705 3112e3fe711a4ed938ec870b4e93138c 221 SUPERFAMILY SSF53639 16 209 6.28E-37 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TL08_12705 3112e3fe711a4ed938ec870b4e93138c 221 Gene3D G3DSA:3.40.225.10 12 216 4.9E-43 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TL08_12705 3112e3fe711a4ed938ec870b4e93138c 221 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 18 202 1.7E-33 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TL08_12705 3112e3fe711a4ed938ec870b4e93138c 221 SMART SM01007 16 205 3.8E-38 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TL08_12705 3112e3fe711a4ed938ec870b4e93138c 221 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 214 73.349 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 TL08_12705 3112e3fe711a4ed938ec870b4e93138c 221 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 21 208 4.3E-49 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 TL08_15680 10d71be96f8b8eb3fd20b73abb13ef00 630 PRINTS PR00113 Alkaline phosphatase signature 37 57 5.3E-17 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TL08_15680 10d71be96f8b8eb3fd20b73abb13ef00 630 PRINTS PR00113 Alkaline phosphatase signature 302 331 5.3E-17 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TL08_15680 10d71be96f8b8eb3fd20b73abb13ef00 630 PRINTS PR00113 Alkaline phosphatase signature 205 215 5.3E-17 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TL08_15680 10d71be96f8b8eb3fd20b73abb13ef00 630 SUPERFAMILY SSF53649 24 458 2.18E-83 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TL08_15680 10d71be96f8b8eb3fd20b73abb13ef00 630 Pfam PF00245 Alkaline phosphatase 38 380 2.9E-49 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TL08_15680 10d71be96f8b8eb3fd20b73abb13ef00 630 SMART SM00098 38 459 1.7E-12 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TL08_15680 10d71be96f8b8eb3fd20b73abb13ef00 630 Gene3D G3DSA:3.40.720.10 23 456 7.7E-97 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TL08_11640 dee35b82bf62bc3781fe71277ba13894 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 1.7E-20 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TL08_11640 dee35b82bf62bc3781fe71277ba13894 78 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 2.3E-6 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TL08_11640 dee35b82bf62bc3781fe71277ba13894 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 2.3E-6 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TL08_11640 dee35b82bf62bc3781fe71277ba13894 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 2.3E-6 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TL08_11640 dee35b82bf62bc3781fe71277ba13894 78 Pfam PF03840 Preprotein translocase SecG subunit 4 72 5.6E-19 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TL08_19585 06c268075b8bdf019b553f23c32bf649 459 SUPERFAMILY SSF53613 4 289 6.39E-29 T 12-10-2018 IPR029056 Ribokinase-like TL08_19585 06c268075b8bdf019b553f23c32bf649 459 Gene3D G3DSA:3.40.50.620 303 458 2.2E-31 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_19585 06c268075b8bdf019b553f23c32bf649 459 SUPERFAMILY SSF52374 326 451 2.56E-21 T 12-10-2018 TL08_19585 06c268075b8bdf019b553f23c32bf649 459 Pfam PF01467 Cytidylyltransferase-like 329 420 1.5E-14 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TL08_19585 06c268075b8bdf019b553f23c32bf649 459 Pfam PF00294 pfkB family carbohydrate kinase 174 292 1.5E-13 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_19585 06c268075b8bdf019b553f23c32bf649 459 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 327 391 1.8E-15 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TL08_19585 06c268075b8bdf019b553f23c32bf649 459 Gene3D G3DSA:3.40.1190.20 2 296 1.4E-57 T 12-10-2018 IPR029056 Ribokinase-like TL08_04500 ec9d25ab077f9e9e89e6b8f0ea63f470 569 Pfam PF06259 Alpha/beta hydrolase 312 486 3.3E-40 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 TL08_04500 ec9d25ab077f9e9e89e6b8f0ea63f470 569 SUPERFAMILY SSF53474 322 483 2.09E-6 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_04500 ec9d25ab077f9e9e89e6b8f0ea63f470 569 Gene3D G3DSA:1.10.287.1060 11 95 8.9E-6 T 12-10-2018 TL08_14785 ceebf7eba54e4f5454bb22584e5b6f4a 560 Pfam PF05960 Bacterial protein of unknown function (DUF885) 29 543 1.5E-132 T 12-10-2018 IPR010281 Protein of unknown function DUF885 TL08_07390 d6393f8aa214c74b00b6549ec3fe87d7 221 Gene3D G3DSA:1.10.3720.10 3 218 4.7E-49 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07390 d6393f8aa214c74b00b6549ec3fe87d7 221 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 4 215 1.8E-86 T 12-10-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD TL08_07390 d6393f8aa214c74b00b6549ec3fe87d7 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 215 2.0E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_07390 d6393f8aa214c74b00b6549ec3fe87d7 221 SUPERFAMILY SSF161098 15 207 1.83E-38 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07390 d6393f8aa214c74b00b6549ec3fe87d7 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 1.2E-27 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TL08_26410 2b2d5673e0a74c52e779762fb97fdd71 930 Pfam PF04294 VanW like protein 716 846 6.7E-38 T 12-10-2018 IPR007391 Vancomycin resistance VanW TL08_26410 2b2d5673e0a74c52e779762fb97fdd71 930 Pfam PF12229 Putative peptidoglycan binding domain 568 671 2.2E-11 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain TL08_26025 45df63a3d8db6bdc83e29e03f5710cc4 648 Pfam PF00723 Glycosyl hydrolases family 15 248 613 8.8E-53 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 TL08_26025 45df63a3d8db6bdc83e29e03f5710cc4 648 Gene3D G3DSA:1.50.10.10 248 622 2.7E-82 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_26025 45df63a3d8db6bdc83e29e03f5710cc4 648 SUPERFAMILY SSF48208 234 610 3.4E-98 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_03425 759e790996884088a87241c79a3d17a7 100 Pfam PF12840 Helix-turn-helix domain 16 73 1.5E-9 T 12-10-2018 TL08_03425 759e790996884088a87241c79a3d17a7 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 3.2E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_03425 759e790996884088a87241c79a3d17a7 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 3.2E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_03425 759e790996884088a87241c79a3d17a7 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 3.2E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_03425 759e790996884088a87241c79a3d17a7 100 Gene3D G3DSA:1.10.10.10 4 92 5.4E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03425 759e790996884088a87241c79a3d17a7 100 SUPERFAMILY SSF46785 3 94 7.49E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_03425 759e790996884088a87241c79a3d17a7 100 SMART SM00418 16 93 6.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_12285 2edb99ac812e5a17bff1ebfee32ab6d2 517 SMART SM00220 18 276 2.6E-54 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_12285 2edb99ac812e5a17bff1ebfee32ab6d2 517 Gene3D G3DSA:3.30.200.20 8 101 1.3E-27 T 12-10-2018 TL08_12285 2edb99ac812e5a17bff1ebfee32ab6d2 517 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 141 153 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_12285 2edb99ac812e5a17bff1ebfee32ab6d2 517 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 47 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_12285 2edb99ac812e5a17bff1ebfee32ab6d2 517 Gene3D G3DSA:1.10.510.10 105 278 2.7E-42 T 12-10-2018 TL08_12285 2edb99ac812e5a17bff1ebfee32ab6d2 517 Pfam PF00069 Protein kinase domain 18 268 1.7E-48 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_12285 2edb99ac812e5a17bff1ebfee32ab6d2 517 SUPERFAMILY SSF56112 9 297 5.93E-68 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_20260 86e7fda310eaa3ad27fea169f08abe03 353 Pfam PF01032 FecCD transport family 26 346 1.5E-96 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_20260 86e7fda310eaa3ad27fea169f08abe03 353 SUPERFAMILY SSF81345 12 346 2.88E-84 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_20260 86e7fda310eaa3ad27fea169f08abe03 353 Gene3D G3DSA:1.10.3470.10 15 351 3.7E-106 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_04805 710c740bef2de0607e86e49ec5de9652 262 Gene3D G3DSA:3.40.50.150 3 261 2.5E-87 T 12-10-2018 TL08_04805 710c740bef2de0607e86e49ec5de9652 262 SUPERFAMILY SSF53335 7 243 2.14E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_04805 710c740bef2de0607e86e49ec5de9652 262 PIRSF PIRSF017393 2 262 9.9E-80 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_04805 710c740bef2de0607e86e49ec5de9652 262 Pfam PF04672 S-adenosyl methyltransferase 10 261 8.3E-72 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_06015 a65c4ccf78bd08c069e7329f1224e0be 500 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 84 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_06015 a65c4ccf78bd08c069e7329f1224e0be 500 SUPERFAMILY SSF103473 5 493 1.28E-62 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_06015 a65c4ccf78bd08c069e7329f1224e0be 500 Pfam PF07690 Major Facilitator Superfamily 20 408 2.5E-49 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_06015 a65c4ccf78bd08c069e7329f1224e0be 500 Gene3D G3DSA:1.20.1720.10 14 256 6.4E-43 T 12-10-2018 TL08_06015 a65c4ccf78bd08c069e7329f1224e0be 500 Gene3D G3DSA:1.20.1250.20 265 495 2.2E-18 T 12-10-2018 TL08_02730 8a692634bb95d3f3193656d81c4dcf6c 231 SMART SM00382 31 218 1.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_02730 8a692634bb95d3f3193656d81c4dcf6c 231 SUPERFAMILY SSF52540 5 222 3.28E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_02730 8a692634bb95d3f3193656d81c4dcf6c 231 Gene3D G3DSA:3.40.50.300 2 224 1.2E-66 T 12-10-2018 TL08_02730 8a692634bb95d3f3193656d81c4dcf6c 231 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_02730 8a692634bb95d3f3193656d81c4dcf6c 231 Pfam PF00005 ABC transporter 22 170 4.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_24510 213b90c3cfdc2bcac28f7b2ee781c412 196 Gene3D G3DSA:3.40.630.30 2 141 6.0E-16 T 12-10-2018 TL08_24510 213b90c3cfdc2bcac28f7b2ee781c412 196 Pfam PF00583 Acetyltransferase (GNAT) family 19 130 3.1E-7 T 12-10-2018 IPR000182 GNAT domain TL08_24510 213b90c3cfdc2bcac28f7b2ee781c412 196 SUPERFAMILY SSF55729 1 149 1.26E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_04350 4901240adfa5a9c8dff38efd0cdf112d 454 Gene3D G3DSA:3.30.565.10 322 445 1.4E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_04350 4901240adfa5a9c8dff38efd0cdf112d 454 Pfam PF07730 Histidine kinase 254 322 2.5E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_04350 4901240adfa5a9c8dff38efd0cdf112d 454 Pfam PF13796 Putative sensor 48 226 3.4E-16 T 12-10-2018 IPR025828 Putative sensor domain TL08_04350 4901240adfa5a9c8dff38efd0cdf112d 454 SUPERFAMILY SSF55874 335 444 1.12E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_10950 a363365f4105cc043da79a7f4d63e689 349 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 117 1.4E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_10950 a363365f4105cc043da79a7f4d63e689 349 PRINTS PR00111 Alpha/beta hydrolase fold signature 150 163 1.4E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_10950 a363365f4105cc043da79a7f4d63e689 349 PRINTS PR00111 Alpha/beta hydrolase fold signature 273 287 1.4E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_10950 a363365f4105cc043da79a7f4d63e689 349 Pfam PF12697 Alpha/beta hydrolase family 79 314 7.0E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_10950 a363365f4105cc043da79a7f4d63e689 349 SUPERFAMILY SSF53474 64 324 1.11E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10950 a363365f4105cc043da79a7f4d63e689 349 Gene3D G3DSA:3.40.50.1820 59 326 3.2E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_24765 2dd2e136b295096bd1345a536cb05625 363 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 5 292 2.3E-35 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TL08_24765 2dd2e136b295096bd1345a536cb05625 363 SUPERFAMILY SSF51412 2 362 5.1E-60 T 12-10-2018 TL08_24765 2dd2e136b295096bd1345a536cb05625 363 SMART SM01240 2 363 3.2E-16 T 12-10-2018 TL08_24765 2dd2e136b295096bd1345a536cb05625 363 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 2 361 1.2E-163 T 12-10-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 TL08_24765 2dd2e136b295096bd1345a536cb05625 363 Gene3D G3DSA:3.20.20.70 3 362 1.4E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_02605 d3dbbd9db0662af5f907b901aa32c0c0 121 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 121 17.223 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 TL08_02605 d3dbbd9db0662af5f907b901aa32c0c0 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 21 120 1.4E-29 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02605 d3dbbd9db0662af5f907b901aa32c0c0 121 Gene3D G3DSA:1.20.58.1610 1 121 4.0E-34 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 Gene3D G3DSA:3.40.50.720 4 255 7.0E-85 T 12-10-2018 TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 SUPERFAMILY SSF51735 7 254 5.51E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 180 0.0017 T 12-10-2018 TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 254 3.5E-71 T 12-10-2018 TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_09195 4fa5b1075e683265fadc9e7d2f33b26c 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16595 d070689968676feacae771f23859879f 203 SUPERFAMILY SSF50998 18 202 9.16E-14 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TL08_16595 d070689968676feacae771f23859879f 203 Gene3D G3DSA:2.130.10.10 6 203 6.1E-12 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_16595 d070689968676feacae771f23859879f 203 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 187 201 - T 12-10-2018 IPR019775 WD40 repeat, conserved site TL08_26945 7df9a2226aa72c024eada4751c88431e 216 SUPERFAMILY SSF52172 6 121 1.05E-29 T 12-10-2018 IPR011006 CheY-like superfamily TL08_26945 7df9a2226aa72c024eada4751c88431e 216 SMART SM00448 6 118 1.2E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_26945 7df9a2226aa72c024eada4751c88431e 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 4.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26945 7df9a2226aa72c024eada4751c88431e 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 4.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26945 7df9a2226aa72c024eada4751c88431e 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 4.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26945 7df9a2226aa72c024eada4751c88431e 216 Pfam PF00072 Response regulator receiver domain 8 119 1.1E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_26945 7df9a2226aa72c024eada4751c88431e 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 5.4E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26945 7df9a2226aa72c024eada4751c88431e 216 SMART SM00421 151 208 6.0E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26945 7df9a2226aa72c024eada4751c88431e 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26945 7df9a2226aa72c024eada4751c88431e 216 SUPERFAMILY SSF46894 146 213 4.76E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_26945 7df9a2226aa72c024eada4751c88431e 216 Gene3D G3DSA:3.40.50.12740 6 213 1.2E-59 T 12-10-2018 TL08_20255 e142b4624f9bd33cac1fcd354b1a0a9e 263 SMART SM00382 27 211 8.5E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_20255 e142b4624f9bd33cac1fcd354b1a0a9e 263 SUPERFAMILY SSF52540 3 224 9.18E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20255 e142b4624f9bd33cac1fcd354b1a0a9e 263 Pfam PF00005 ABC transporter 19 167 3.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_20255 e142b4624f9bd33cac1fcd354b1a0a9e 263 Gene3D G3DSA:3.40.50.300 3 251 1.1E-64 T 12-10-2018 TL08_20255 e142b4624f9bd33cac1fcd354b1a0a9e 263 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_00585 366ba4cbe3af0d4e5d7ea83c1c30678d 204 SUPERFAMILY SSF46689 8 81 3.44E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_00585 366ba4cbe3af0d4e5d7ea83c1c30678d 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 61 1.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_00585 366ba4cbe3af0d4e5d7ea83c1c30678d 204 Gene3D G3DSA:1.10.10.60 7 56 1.9E-21 T 12-10-2018 TL08_00585 366ba4cbe3af0d4e5d7ea83c1c30678d 204 Gene3D G3DSA:1.10.357.10 58 199 1.1E-30 T 12-10-2018 TL08_00585 366ba4cbe3af0d4e5d7ea83c1c30678d 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_25005 703c3fd965d624d425eb8783af2e1088 299 Gene3D G3DSA:3.10.180.10 159 285 3.3E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_25005 703c3fd965d624d425eb8783af2e1088 299 Gene3D G3DSA:3.10.180.10 16 153 1.7E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_25005 703c3fd965d624d425eb8783af2e1088 299 SUPERFAMILY SSF54593 165 281 9.49E-15 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_25005 703c3fd965d624d425eb8783af2e1088 299 SUPERFAMILY SSF54593 21 152 2.19E-8 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_18985 b146944030df93cb209551a730ae5838 381 Gene3D G3DSA:3.20.20.70 20 373 1.9E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_18985 b146944030df93cb209551a730ae5838 381 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 22 365 1.5E-58 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 TL08_18985 b146944030df93cb209551a730ae5838 381 SUPERFAMILY SSF51395 21 370 4.35E-91 T 12-10-2018 TL08_17000 4c8d67faeceb8420b3bbb1c6866d4bd7 464 SUPERFAMILY SSF75304 4 456 9.16E-133 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_17000 4c8d67faeceb8420b3bbb1c6866d4bd7 464 Gene3D G3DSA:3.90.1300.10 7 456 7.1E-140 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_17000 4c8d67faeceb8420b3bbb1c6866d4bd7 464 ProSitePatterns PS00571 Amidases signature. 148 179 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TL08_17000 4c8d67faeceb8420b3bbb1c6866d4bd7 464 Pfam PF01425 Amidase 25 444 5.0E-120 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TL08_01175 22dd7bd93ee2db8123fa9b133f562b9f 625 Gene3D G3DSA:3.40.50.1820 370 621 8.1E-66 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_01175 22dd7bd93ee2db8123fa9b133f562b9f 625 Pfam PF00326 Prolyl oligopeptidase family 412 619 2.3E-44 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_01175 22dd7bd93ee2db8123fa9b133f562b9f 625 Gene3D G3DSA:2.120.10.30 138 369 4.3E-13 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_01175 22dd7bd93ee2db8123fa9b133f562b9f 625 Gene3D G3DSA:2.120.10.30 14 124 1.6E-7 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_01175 22dd7bd93ee2db8123fa9b133f562b9f 625 SUPERFAMILY SSF82171 40 354 2.63E-20 T 12-10-2018 TL08_01175 22dd7bd93ee2db8123fa9b133f562b9f 625 SUPERFAMILY SSF53474 376 619 2.54E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16310 f9095633a92c372ff61b82dd3f16bb73 339 Pfam PF08242 Methyltransferase domain 165 269 2.2E-9 T 12-10-2018 IPR013217 Methyltransferase type 12 TL08_16310 f9095633a92c372ff61b82dd3f16bb73 339 Gene3D G3DSA:3.40.50.150 163 326 1.4E-30 T 12-10-2018 TL08_16310 f9095633a92c372ff61b82dd3f16bb73 339 SUPERFAMILY SSF53335 147 337 7.19E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_02215 521be301c58ec64f58b94b8f7d20111b 307 SUPERFAMILY SSF51679 14 290 4.54E-42 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_02215 521be301c58ec64f58b94b8f7d20111b 307 Pfam PF00296 Luciferase-like monooxygenase 14 280 1.5E-25 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_02215 521be301c58ec64f58b94b8f7d20111b 307 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 12 305 4.3E-99 T 12-10-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted TL08_02215 521be301c58ec64f58b94b8f7d20111b 307 Gene3D G3DSA:3.20.20.30 15 297 4.4E-38 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_15290 0c423eefb551db4e3811614763f01b14 180 Pfam PF12796 Ankyrin repeats (3 copies) 46 137 4.6E-15 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain TL08_15290 0c423eefb551db4e3811614763f01b14 180 PRINTS PR01415 Ankyrin repeat signature 124 138 3.3E-7 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 TL08_15290 0c423eefb551db4e3811614763f01b14 180 PRINTS PR01415 Ankyrin repeat signature 73 88 3.3E-7 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 TL08_15290 0c423eefb551db4e3811614763f01b14 180 SUPERFAMILY SSF48403 41 175 3.95E-22 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TL08_15290 0c423eefb551db4e3811614763f01b14 180 Gene3D G3DSA:1.25.40.20 22 179 2.6E-28 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily TL08_15290 0c423eefb551db4e3811614763f01b14 180 SMART SM00248 72 101 0.0044 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 TL08_15290 0c423eefb551db4e3811614763f01b14 180 SMART SM00248 108 137 1.8E-4 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 TL08_15290 0c423eefb551db4e3811614763f01b14 180 SMART SM00248 150 180 8.2 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 TL08_04675 f17d1e3d338e9887d9344e8303622122 318 SUPERFAMILY SSF51621 5 250 4.47E-64 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TL08_04675 f17d1e3d338e9887d9344e8303622122 318 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 240 7.6E-43 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 TL08_04675 f17d1e3d338e9887d9344e8303622122 318 Gene3D G3DSA:3.20.20.60 1 315 7.1E-94 T 12-10-2018 TL08_04675 f17d1e3d338e9887d9344e8303622122 318 PIRSF PIRSF015582 2 317 2.0E-86 T 12-10-2018 IPR011206 Citrate lyase beta subunit-like TL08_06040 ec6852dfdca56ae9f9da3d4133dda2a1 133 Gene3D G3DSA:1.10.10.10 4 132 1.5E-42 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06040 ec6852dfdca56ae9f9da3d4133dda2a1 133 SUPERFAMILY SSF46785 23 129 3.71E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_06040 ec6852dfdca56ae9f9da3d4133dda2a1 133 Pfam PF01638 HxlR-like helix-turn-helix 33 120 5.6E-30 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_25140 c6da386c880674fc500fced8f493dd6a 378 PIRSF PIRSF000525 11 378 4.7E-77 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 TL08_25140 c6da386c880674fc500fced8f493dd6a 378 Gene3D G3DSA:3.90.1150.10 273 377 8.8E-41 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_25140 c6da386c880674fc500fced8f493dd6a 378 Pfam PF00266 Aminotransferase class-V 39 336 1.1E-12 T 12-10-2018 IPR000192 Aminotransferase class V domain TL08_25140 c6da386c880674fc500fced8f493dd6a 378 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 11 377 24.121 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 TL08_25140 c6da386c880674fc500fced8f493dd6a 378 SUPERFAMILY SSF53383 23 377 1.55E-73 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_25140 c6da386c880674fc500fced8f493dd6a 378 Gene3D G3DSA:3.40.640.10 33 271 4.7E-58 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_25140 c6da386c880674fc500fced8f493dd6a 378 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 18 377 1.4E-196 T 12-10-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 TL08_27025 a5ecf8494dc38ebbebb4b8d44f00b283 261 Pfam PF14011 EspG family 16 256 1.3E-47 T 12-10-2018 IPR025734 EspG family TL08_26095 6c0bb13ba3ea35cdc8045a301dd69d1a 280 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 2.8E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26095 6c0bb13ba3ea35cdc8045a301dd69d1a 280 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 2.8E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26095 6c0bb13ba3ea35cdc8045a301dd69d1a 280 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 2.8E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26095 6c0bb13ba3ea35cdc8045a301dd69d1a 280 SMART SM00422 2 71 2.6E-22 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26095 6c0bb13ba3ea35cdc8045a301dd69d1a 280 Gene3D G3DSA:1.10.1660.10 1 115 5.5E-24 T 12-10-2018 TL08_26095 6c0bb13ba3ea35cdc8045a301dd69d1a 280 Pfam PF13411 MerR HTH family regulatory protein 2 69 5.9E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_26095 6c0bb13ba3ea35cdc8045a301dd69d1a 280 SUPERFAMILY SSF46955 2 111 5.13E-25 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_07240 223e83739dded66bed76858c7412d734 435 Gene3D G3DSA:3.30.70.260 350 421 7.0E-139 T 12-10-2018 TL08_07240 223e83739dded66bed76858c7412d734 435 PIRSF PIRSF000098 6 433 1.3E-151 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TL08_07240 223e83739dded66bed76858c7412d734 435 Gene3D G3DSA:3.30.360.10 138 349 7.0E-139 T 12-10-2018 TL08_07240 223e83739dded66bed76858c7412d734 435 SUPERFAMILY SSF55021 352 425 6.25E-10 T 12-10-2018 TL08_07240 223e83739dded66bed76858c7412d734 435 SUPERFAMILY SSF51735 7 160 3.31E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_07240 223e83739dded66bed76858c7412d734 435 Gene3D G3DSA:3.40.50.720 9 341 7.0E-139 T 12-10-2018 TL08_07240 223e83739dded66bed76858c7412d734 435 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 15 131 1.2E-22 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TL08_07240 223e83739dded66bed76858c7412d734 435 SUPERFAMILY SSF55347 139 309 9.15E-49 T 12-10-2018 TL08_07240 223e83739dded66bed76858c7412d734 435 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TL08_07240 223e83739dded66bed76858c7412d734 435 Pfam PF00742 Homoserine dehydrogenase 139 322 6.0E-64 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TL08_07240 223e83739dded66bed76858c7412d734 435 Pfam PF01842 ACT domain 357 418 2.3E-7 T 12-10-2018 IPR002912 ACT domain TL08_10140 7c83a2925b2ef92b7cba53f85aa11f31 231 Pfam PF10935 Protein of unknown function (DUF2637) 19 153 1.4E-7 T 12-10-2018 IPR021235 Protein of unknown function DUF2637 TL08_01790 0400e01c91e8cb3a248d15c4bc004501 162 Pfam PF02559 CarD-like/TRCF domain 3 111 2.0E-18 T 12-10-2018 IPR003711 CarD-like/TRCF domain TL08_01790 0400e01c91e8cb3a248d15c4bc004501 162 Gene3D G3DSA:1.20.58.1290 61 162 1.1E-38 T 12-10-2018 TL08_01790 0400e01c91e8cb3a248d15c4bc004501 162 SMART SM01058 2 112 1.1E-32 T 12-10-2018 IPR003711 CarD-like/TRCF domain TL08_01790 0400e01c91e8cb3a248d15c4bc004501 162 Gene3D G3DSA:2.30.30.840 1 60 4.6E-26 T 12-10-2018 TL08_01790 0400e01c91e8cb3a248d15c4bc004501 162 SUPERFAMILY SSF141259 3 65 3.53E-14 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily TL08_13545 d08e6d132da82c697c5aa3c39e27689f 555 SUPERFAMILY SSF51905 18 521 4.94E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_13545 d08e6d132da82c697c5aa3c39e27689f 555 Gene3D G3DSA:3.50.50.60 20 109 1.6E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_13545 d08e6d132da82c697c5aa3c39e27689f 555 Gene3D G3DSA:3.50.50.60 205 325 2.8E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_13545 d08e6d132da82c697c5aa3c39e27689f 555 Pfam PF01593 Flavin containing amine oxidoreductase 29 299 1.5E-11 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TL08_20650 ead7f22e9c512480b31b71a7b881cbea 383 SUPERFAMILY SSF51735 49 173 1.09E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_20650 ead7f22e9c512480b31b71a7b881cbea 383 Gene3D G3DSA:3.40.50.720 1 140 2.8E-34 T 12-10-2018 TL08_20650 ead7f22e9c512480b31b71a7b881cbea 383 SUPERFAMILY SSF55347 146 332 1.5E-29 T 12-10-2018 TL08_20650 ead7f22e9c512480b31b71a7b881cbea 383 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 152 228 4.5E-5 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TL08_20650 ead7f22e9c512480b31b71a7b881cbea 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 138 4.9E-7 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_20650 ead7f22e9c512480b31b71a7b881cbea 383 Gene3D G3DSA:3.30.360.10 141 381 3.9E-66 T 12-10-2018 TL08_09845 3378cfbbf31d76a4d8354e215d9a5c69 254 PIRSF PIRSF006324 26 253 2.3E-45 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TL08_09845 3378cfbbf31d76a4d8354e215d9a5c69 254 Pfam PF01810 LysE type translocator 38 250 1.1E-29 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TL08_08245 164f4080bc1f90d1ed3c0cd61fe2ac3b 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 277 1.7E-84 T 12-10-2018 IPR003797 DegV TL08_08245 164f4080bc1f90d1ed3c0cd61fe2ac3b 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 3.2E-79 T 12-10-2018 IPR003797 DegV TL08_08245 164f4080bc1f90d1ed3c0cd61fe2ac3b 286 Gene3D G3DSA:3.40.50.10170 1 151 1.3E-42 T 12-10-2018 TL08_08245 164f4080bc1f90d1ed3c0cd61fe2ac3b 286 Gene3D G3DSA:3.30.1180.10 153 278 4.9E-40 T 12-10-2018 TL08_08245 164f4080bc1f90d1ed3c0cd61fe2ac3b 286 SUPERFAMILY SSF82549 1 279 2.62E-76 T 12-10-2018 TL08_11805 769de98b5090ff8faeb6ae89bbe3752d 489 SUPERFAMILY SSF101960 55 486 1.18E-139 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TL08_11805 769de98b5090ff8faeb6ae89bbe3752d 489 Pfam PF01458 Uncharacterized protein family (UPF0051) 235 460 5.5E-76 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TL08_11805 769de98b5090ff8faeb6ae89bbe3752d 489 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 33 480 1.9E-219 T 12-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 TL08_03705 2150bb3b9b342f1137cff8c1ef196a14 564 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 388 545 2.1E-39 T 12-10-2018 IPR000160 GGDEF domain TL08_03705 2150bb3b9b342f1137cff8c1ef196a14 564 SMART SM00267 380 546 1.8E-42 T 12-10-2018 IPR000160 GGDEF domain TL08_03705 2150bb3b9b342f1137cff8c1ef196a14 564 Pfam PF00990 Diguanylate cyclase, GGDEF domain 391 541 1.3E-37 T 12-10-2018 IPR000160 GGDEF domain TL08_03705 2150bb3b9b342f1137cff8c1ef196a14 564 SUPERFAMILY SSF55073 396 544 2.94E-39 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_03705 2150bb3b9b342f1137cff8c1ef196a14 564 Gene3D G3DSA:3.30.70.270 377 546 1.2E-47 T 12-10-2018 TL08_22185 ed986079153dde682abe6768da1cbfba 183 Pfam PF14016 Protein of unknown function (DUF4232) 43 155 1.7E-13 T 12-10-2018 IPR025326 Protein of unknown function DUF4232 TL08_00280 098d1f753b80ae7dff717fa944bd533b 542 SUPERFAMILY SSF53098 447 531 3.64E-5 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_00280 098d1f753b80ae7dff717fa944bd533b 542 Pfam PF13482 RNase_H superfamily 443 528 7.4E-11 T 12-10-2018 IPR038720 YprB, ribonuclease H-like domain TL08_00280 098d1f753b80ae7dff717fa944bd533b 542 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 10 528 2.2E-61 T 12-10-2018 IPR019993 RecB family nuclease, TM0106, putative TL08_02115 4a02df97b7456f511957ee6f491669c2 385 Gene3D G3DSA:3.30.300.50 39 116 9.9E-10 T 12-10-2018 IPR035070 Streptogrisin prodomain TL08_02115 4a02df97b7456f511957ee6f491669c2 385 Gene3D G3DSA:2.40.10.10 272 370 3.7E-73 T 12-10-2018 TL08_02115 4a02df97b7456f511957ee6f491669c2 385 Gene3D G3DSA:2.40.10.10 204 381 3.7E-73 T 12-10-2018 TL08_02115 4a02df97b7456f511957ee6f491669c2 385 PIRSF PIRSF001134 2 385 2.0E-127 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02115 4a02df97b7456f511957ee6f491669c2 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 305 322 5.5E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02115 4a02df97b7456f511957ee6f491669c2 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 348 362 5.5E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02115 4a02df97b7456f511957ee6f491669c2 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 324 347 5.5E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02115 4a02df97b7456f511957ee6f491669c2 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 224 238 5.5E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02115 4a02df97b7456f511957ee6f491669c2 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 284 304 5.5E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02115 4a02df97b7456f511957ee6f491669c2 385 SUPERFAMILY SSF50494 208 376 3.29E-33 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_02115 4a02df97b7456f511957ee6f491669c2 385 Pfam PF02983 Alpha-lytic protease prodomain 125 182 3.8E-11 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 TL08_02115 4a02df97b7456f511957ee6f491669c2 385 Gene3D G3DSA:3.30.300.50 122 195 4.0E-5 T 12-10-2018 IPR035070 Streptogrisin prodomain TL08_21740 3e13d2c59aed22da27632c89dc820563 95 Gene3D G3DSA:3.30.70.920 1 74 4.4E-18 T 12-10-2018 TL08_21740 3e13d2c59aed22da27632c89dc820563 95 Pfam PF01037 Lrp/AsnC ligand binding domain 13 76 2.6E-14 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TL08_21740 3e13d2c59aed22da27632c89dc820563 95 SUPERFAMILY SSF54909 2 77 8.98E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_06175 c362d0223f2d35ac0c2a55785c65fccb 306 SUPERFAMILY SSF63829 8 266 8.28E-36 T 12-10-2018 TL08_06175 c362d0223f2d35ac0c2a55785c65fccb 306 PIRSF PIRSF026412 5 300 4.3E-102 T 12-10-2018 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 TL08_06175 c362d0223f2d35ac0c2a55785c65fccb 306 Hamap MF_01282 Virginiamycin B lyase [vgb]. 11 298 43.282 T 12-10-2018 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 TL08_06175 c362d0223f2d35ac0c2a55785c65fccb 306 Gene3D G3DSA:2.130.10.10 46 297 4.3E-94 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 SUPERFAMILY SSF52172 7 140 1.15E-37 T 12-10-2018 IPR011006 CheY-like superfamily TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 Gene3D G3DSA:3.40.50.12740 8 221 6.3E-65 T 12-10-2018 TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 SMART SM00421 159 216 1.6E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 1.3E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 1.3E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 1.3E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 SMART SM00448 8 121 3.0E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 215 5.0E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 Pfam PF00072 Response regulator receiver domain 10 121 5.3E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_21120 6cfff75065fa020e3b772fb6be217ca4 226 SUPERFAMILY SSF46894 152 221 2.31E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_11905 db02bfc44a985fac7319c2d02d3d8616 285 SUPERFAMILY SSF51735 5 279 1.33E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_11905 db02bfc44a985fac7319c2d02d3d8616 285 Gene3D G3DSA:3.40.50.720 7 285 8.4E-68 T 12-10-2018 TL08_11905 db02bfc44a985fac7319c2d02d3d8616 285 Pfam PF13460 NAD(P)H-binding 11 186 1.2E-25 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_12915 4a7abc164d7289c02b8f6f563dbfb501 427 SUPERFAMILY SSF89796 36 427 1.2E-133 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TL08_12915 4a7abc164d7289c02b8f6f563dbfb501 427 Pfam PF02515 CoA-transferase family III 38 403 1.7E-129 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 TL08_12915 4a7abc164d7289c02b8f6f563dbfb501 427 Gene3D G3DSA:3.30.1540.10 263 354 6.1E-136 T 12-10-2018 TL08_12915 4a7abc164d7289c02b8f6f563dbfb501 427 Gene3D G3DSA:3.40.50.10540 38 421 6.1E-136 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TL08_05740 d58c257c1dab51ada02912e344290b66 347 SUPERFAMILY SSF51126 8 309 2.2E-36 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_05740 d58c257c1dab51ada02912e344290b66 347 Gene3D G3DSA:2.160.20.10 15 343 2.2E-34 T 12-10-2018 IPR012334 Pectin lyase fold TL08_05740 d58c257c1dab51ada02912e344290b66 347 Pfam PF13229 Right handed beta helix region 84 236 2.8E-15 T 12-10-2018 IPR039448 Right handed beta helix domain TL08_05740 d58c257c1dab51ada02912e344290b66 347 SMART SM00710 92 114 4300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_05740 d58c257c1dab51ada02912e344290b66 347 SMART SM00710 115 137 2400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_05740 d58c257c1dab51ada02912e344290b66 347 SMART SM00710 185 206 1000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_05740 d58c257c1dab51ada02912e344290b66 347 SMART SM00710 217 240 670.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_05740 d58c257c1dab51ada02912e344290b66 347 SMART SM00710 138 160 110.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_05740 d58c257c1dab51ada02912e344290b66 347 SMART SM00710 163 184 710.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 Pfam PF00246 Zinc carboxypeptidase 131 406 6.1E-63 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 Gene3D G3DSA:3.40.630.10 117 429 1.5E-95 T 12-10-2018 TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 171 193 - T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 149 161 1.5E-13 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 171 185 1.5E-13 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 247 255 1.5E-13 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 306 319 1.5E-13 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 309 319 - T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 SMART SM00631 123 405 1.4E-82 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 TL08_09675 5bbab4dc3bf97cb7d2e23624609de02b 431 SUPERFAMILY SSF53187 120 418 1.09E-77 T 12-10-2018 TL08_09745 8a391e0a07f9ea73d3380fbb65bc2565 257 Pfam PF00977 Histidine biosynthesis protein 6 240 5.1E-83 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TL08_09745 8a391e0a07f9ea73d3380fbb65bc2565 257 SUPERFAMILY SSF51366 5 257 1.57E-76 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TL08_09745 8a391e0a07f9ea73d3380fbb65bc2565 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 4 257 1.2E-107 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TL08_09745 8a391e0a07f9ea73d3380fbb65bc2565 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 257 46.471 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TL08_09745 8a391e0a07f9ea73d3380fbb65bc2565 257 Gene3D G3DSA:3.20.20.70 1 257 3.7E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_04425 8a4187f0c8008981ec38ff37e7821871 604 Gene3D G3DSA:3.90.76.10 99 205 2.1E-166 T 12-10-2018 TL08_04425 8a4187f0c8008981ec38ff37e7821871 604 Gene3D G3DSA:3.40.190.10 67 583 2.1E-166 T 12-10-2018 TL08_04425 8a4187f0c8008981ec38ff37e7821871 604 Gene3D G3DSA:3.10.105.10 313 571 2.1E-166 T 12-10-2018 TL08_04425 8a4187f0c8008981ec38ff37e7821871 604 SUPERFAMILY SSF53850 66 595 1.7E-57 T 12-10-2018 TL08_04425 8a4187f0c8008981ec38ff37e7821871 604 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 123 461 1.3E-34 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 Gene3D G3DSA:3.90.105.10 22 172 1.7E-89 T 12-10-2018 TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 SMART SM00852 178 317 9.8E-22 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 Pfam PF00994 Probable molybdopterin binding domain 179 316 1.7E-16 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 Pfam PF03454 MoeA C-terminal region (domain IV) 331 403 5.9E-19 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 Gene3D G3DSA:2.40.340.10 328 400 2.1E-20 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 Gene3D G3DSA:2.170.190.11 44 139 1.7E-89 T 12-10-2018 TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 SUPERFAMILY SSF53218 175 321 4.58E-30 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 SUPERFAMILY SSF63882 1 174 7.46E-47 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 Gene3D G3DSA:3.40.980.10 173 316 1.7E-89 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 165 4.6E-42 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_03275 80606ccc96c3f2ff25a1bc7fbac8d4c9 407 SUPERFAMILY SSF63867 326 403 9.16E-18 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_01265 34dc5364ad0760eeba9e89c6d5858384 288 SUPERFAMILY SSF55811 21 227 2.09E-17 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_01265 34dc5364ad0760eeba9e89c6d5858384 288 Gene3D G3DSA:3.90.79.10 22 255 8.3E-70 T 12-10-2018 TL08_01545 1caf27e7328b09d45d94125baccab593 507 Gene3D G3DSA:3.40.50.300 219 484 3.1E-39 T 12-10-2018 TL08_01545 1caf27e7328b09d45d94125baccab593 507 SUPERFAMILY SSF52540 205 473 3.84E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01545 1caf27e7328b09d45d94125baccab593 507 Pfam PF01580 FtsK/SpoIIIE family 238 421 8.6E-16 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TL08_05060 338a454cee7ce05bdc80b151d1cc8e3b 528 Gene3D G3DSA:3.30.300.30 416 523 6.6E-32 T 12-10-2018 TL08_05060 338a454cee7ce05bdc80b151d1cc8e3b 528 Gene3D G3DSA:3.40.50.12780 11 414 2.0E-110 T 12-10-2018 TL08_05060 338a454cee7ce05bdc80b151d1cc8e3b 528 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 508 1.9E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_05060 338a454cee7ce05bdc80b151d1cc8e3b 528 SUPERFAMILY SSF56801 13 517 1.01E-131 T 12-10-2018 TL08_05060 338a454cee7ce05bdc80b151d1cc8e3b 528 Pfam PF00501 AMP-binding enzyme 16 422 2.6E-82 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_05060 338a454cee7ce05bdc80b151d1cc8e3b 528 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_05060 338a454cee7ce05bdc80b151d1cc8e3b 528 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 37 446 1.6E-107 T 12-10-2018 IPR010071 Amino acid adenylation domain TL08_19765 e64b11b414313bda97d9fc97be244d38 429 Pfam PF07690 Major Facilitator Superfamily 24 361 1.1E-29 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_19765 e64b11b414313bda97d9fc97be244d38 429 SUPERFAMILY SSF103473 13 401 2.75E-50 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_19765 e64b11b414313bda97d9fc97be244d38 429 Gene3D G3DSA:1.20.1250.20 21 409 5.7E-40 T 12-10-2018 TL08_16605 8fce31050e35ad1b850fe1dd0bd9d9b7 310 SUPERFAMILY SSF46785 2 109 5.45E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16605 8fce31050e35ad1b850fe1dd0bd9d9b7 310 Gene3D G3DSA:3.40.190.290 94 297 2.7E-25 T 12-10-2018 TL08_16605 8fce31050e35ad1b850fe1dd0bd9d9b7 310 Pfam PF03466 LysR substrate binding domain 96 293 1.1E-26 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_16605 8fce31050e35ad1b850fe1dd0bd9d9b7 310 SUPERFAMILY SSF53850 94 296 1.72E-29 T 12-10-2018 TL08_16605 8fce31050e35ad1b850fe1dd0bd9d9b7 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.0E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_16605 8fce31050e35ad1b850fe1dd0bd9d9b7 310 Gene3D G3DSA:1.10.10.10 3 89 5.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 Gene3D G3DSA:1.10.630.10 11 408 1.0E-101 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 SUPERFAMILY SSF48264 14 408 4.19E-81 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 Pfam PF00067 Cytochrome P450 198 377 9.9E-24 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00385 P450 superfamily signature 281 292 1.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00385 P450 superfamily signature 357 368 1.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00385 P450 superfamily signature 246 263 1.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00385 P450 superfamily signature 348 357 1.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00359 B-class P450 signature 95 106 1.7E-40 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00359 B-class P450 signature 299 326 1.7E-40 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00359 B-class P450 signature 200 222 1.7E-40 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00359 B-class P450 signature 142 158 1.7E-40 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00359 B-class P450 signature 348 357 1.7E-40 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00359 B-class P450 signature 357 368 1.7E-40 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00359 B-class P450 signature 327 342 1.7E-40 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_14420 ab43a9deb5dc72775f17d6ec28569289 408 PRINTS PR00359 B-class P450 signature 281 292 1.7E-40 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_08260 c87af42038d4b539288da8b339d19906 420 TIGRFAM TIGR00260 thrC: threonine synthase 66 394 2.1E-84 T 12-10-2018 IPR004450 Threonine synthase-like TL08_08260 c87af42038d4b539288da8b339d19906 420 Gene3D G3DSA:3.40.50.1100 68 393 4.6E-102 T 12-10-2018 TL08_08260 c87af42038d4b539288da8b339d19906 420 Gene3D G3DSA:3.40.50.1100 120 217 4.6E-102 T 12-10-2018 TL08_08260 c87af42038d4b539288da8b339d19906 420 SUPERFAMILY SSF53686 16 409 6.02E-86 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_08260 c87af42038d4b539288da8b339d19906 420 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 87 388 5.1E-66 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 Pfam PF00072 Response regulator receiver domain 4 115 1.5E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 SUPERFAMILY SSF52172 3 122 1.85E-16 T 12-10-2018 IPR011006 CheY-like superfamily TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 SUPERFAMILY SSF46894 125 197 1.94E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 Gene3D G3DSA:1.10.10.10 129 198 5.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 SMART SM00421 134 191 6.1E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 ProSitePatterns PS00622 LuxR-type HTH domain signature. 151 178 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 189 2.2E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 Gene3D G3DSA:3.40.50.2300 2 128 5.9E-19 T 12-10-2018 TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 8.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 8.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 8.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24790 a09c3f1cc198baa3a2371798600cb34b 198 SMART SM00448 2 115 9.9E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_11730 ff080ccd347f01e0514ee6c39ad15c05 322 Gene3D G3DSA:3.40.50.720 121 266 1.4E-110 T 12-10-2018 TL08_11730 ff080ccd347f01e0514ee6c39ad15c05 322 SMART SM00829 10 320 2.0E-25 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_11730 ff080ccd347f01e0514ee6c39ad15c05 322 Gene3D G3DSA:3.90.180.10 10 318 1.4E-110 T 12-10-2018 TL08_11730 ff080ccd347f01e0514ee6c39ad15c05 322 SUPERFAMILY SSF50129 1 142 1.83E-36 T 12-10-2018 IPR011032 GroES-like superfamily TL08_11730 ff080ccd347f01e0514ee6c39ad15c05 322 Pfam PF00107 Zinc-binding dehydrogenase 149 253 3.4E-29 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_11730 ff080ccd347f01e0514ee6c39ad15c05 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 2.8E-10 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_11730 ff080ccd347f01e0514ee6c39ad15c05 322 SUPERFAMILY SSF51735 114 280 1.67E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 Pfam PF00549 CoA-ligase 158 274 9.0E-14 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 PIRSF PIRSF001553 1 295 1.0E-115 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 2.5E-33 T 12-10-2018 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 2.5E-33 T 12-10-2018 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 2.5E-33 T 12-10-2018 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 2.5E-33 T 12-10-2018 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 Gene3D G3DSA:3.40.50.720 1 129 7.1E-47 T 12-10-2018 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 Pfam PF02629 CoA binding domain 7 103 5.1E-26 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 SUPERFAMILY SSF51735 1 128 3.67E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 Gene3D G3DSA:3.40.50.261 130 292 2.0E-58 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 SMART SM00881 4 104 4.5E-33 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 SUPERFAMILY SSF52210 129 289 4.97E-44 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 39.158 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TL08_24590 65d4dc83ca4ceaf89032683d52b1c516 297 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 290 9.2E-124 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TL08_07985 7e293d35b17bcf95eb2172f01f4ae8ac 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 261 5.4E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_07985 7e293d35b17bcf95eb2172f01f4ae8ac 270 Gene3D G3DSA:1.10.3720.10 15 266 1.7E-68 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07985 7e293d35b17bcf95eb2172f01f4ae8ac 270 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 59 262 1.8E-71 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 TL08_07985 7e293d35b17bcf95eb2172f01f4ae8ac 270 SUPERFAMILY SSF161098 17 261 1.42E-52 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07985 7e293d35b17bcf95eb2172f01f4ae8ac 270 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 38 259 7.7E-71 T 12-10-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0016020|GO:0055085 TL08_01055 19b62c9152144a0521f9b36a6beccbc2 294 Pfam PF04616 Glycosyl hydrolases family 43 76 207 1.5E-8 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 TL08_01055 19b62c9152144a0521f9b36a6beccbc2 294 SUPERFAMILY SSF75005 74 257 1.06E-21 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_01055 19b62c9152144a0521f9b36a6beccbc2 294 Gene3D G3DSA:2.115.10.20 71 291 4.1E-15 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_25670 5813d80d1527aef52f3f1890669c94b5 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 235 2.4E-40 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_25670 5813d80d1527aef52f3f1890669c94b5 345 SUPERFAMILY SSF51735 1 310 1.75E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_25670 5813d80d1527aef52f3f1890669c94b5 345 Gene3D G3DSA:3.40.50.720 1 304 6.3E-48 T 12-10-2018 TL08_21105 866b8667b682a60ed0d79b9aa3eb67e3 273 Gene3D G3DSA:1.10.10.10 3 74 5.9E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21105 866b8667b682a60ed0d79b9aa3eb67e3 273 SUPERFAMILY SSF46785 2 68 3.56E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_21105 866b8667b682a60ed0d79b9aa3eb67e3 273 SMART SM00345 5 64 6.6E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_21105 866b8667b682a60ed0d79b9aa3eb67e3 273 Gene3D G3DSA:3.40.1410.10 91 254 4.6E-26 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_21105 866b8667b682a60ed0d79b9aa3eb67e3 273 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 58 7.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_21105 866b8667b682a60ed0d79b9aa3eb67e3 273 SUPERFAMILY SSF64288 116 253 1.13E-14 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_21105 866b8667b682a60ed0d79b9aa3eb67e3 273 SMART SM00866 110 251 0.0037 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_21105 866b8667b682a60ed0d79b9aa3eb67e3 273 Pfam PF07702 UTRA domain 116 250 4.2E-10 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_20495 b779aacbf5b6d5259a47daca04f14804 373 Gene3D G3DSA:2.40.50.140 201 348 7.7E-26 T 12-10-2018 TL08_20495 b779aacbf5b6d5259a47daca04f14804 373 SUPERFAMILY SSF56091 7 199 2.23E-42 T 12-10-2018 TL08_20495 b779aacbf5b6d5259a47daca04f14804 373 Pfam PF01068 ATP dependent DNA ligase domain 11 199 3.3E-28 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 TL08_20495 b779aacbf5b6d5259a47daca04f14804 373 Pfam PF04679 ATP dependent DNA ligase C terminal region 221 341 3.6E-15 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 TL08_20495 b779aacbf5b6d5259a47daca04f14804 373 Gene3D G3DSA:3.30.470.30 8 199 3.3E-36 T 12-10-2018 TL08_20495 b779aacbf5b6d5259a47daca04f14804 373 SUPERFAMILY SSF50249 202 347 1.46E-10 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_20075 14e557c4ef35b1c608140cc06df6a3cb 883 SUPERFAMILY SSF52540 334 734 1.49E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20075 14e557c4ef35b1c608140cc06df6a3cb 883 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 334 738 1.2E-38 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core TL08_20075 14e557c4ef35b1c608140cc06df6a3cb 883 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 48 257 3.7E-17 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain TL08_20075 14e557c4ef35b1c608140cc06df6a3cb 883 Gene3D G3DSA:3.40.50.300 603 755 5.7E-8 T 12-10-2018 TL08_20075 14e557c4ef35b1c608140cc06df6a3cb 883 Gene3D G3DSA:1.10.3210.30 25 305 1.1E-57 T 12-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily TL08_11575 6a9c12001e221110e65f429a0234b403 266 Gene3D G3DSA:3.20.20.70 32 261 1.0E-76 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_11575 6a9c12001e221110e65f429a0234b403 266 PIRSF PIRSF001461 37 266 8.6E-87 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TL08_11575 6a9c12001e221110e65f429a0234b403 266 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 176 198 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TL08_11575 6a9c12001e221110e65f429a0234b403 266 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 74 88 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TL08_11575 6a9c12001e221110e65f429a0234b403 266 SUPERFAMILY SSF51366 42 257 2.4E-59 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TL08_11575 6a9c12001e221110e65f429a0234b403 266 Pfam PF00834 Ribulose-phosphate 3 epimerase family 43 243 1.5E-74 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TL08_11575 6a9c12001e221110e65f429a0234b403 266 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 42 256 5.6E-79 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TL08_12570 a1c4fcb472d7ea80ab92d1780ae29b8c 280 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12570 a1c4fcb472d7ea80ab92d1780ae29b8c 280 SMART SM00382 40 233 1.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12570 a1c4fcb472d7ea80ab92d1780ae29b8c 280 Gene3D G3DSA:3.40.50.300 10 258 9.5E-49 T 12-10-2018 TL08_12570 a1c4fcb472d7ea80ab92d1780ae29b8c 280 SUPERFAMILY SSF52540 12 254 1.36E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12570 a1c4fcb472d7ea80ab92d1780ae29b8c 280 Pfam PF00005 ABC transporter 31 185 8.4E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_08310 6cf846d051071571c0a6ee280542d920 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 4.2E-46 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 TL08_08310 6cf846d051071571c0a6ee280542d920 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 27.852 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 TL08_08310 6cf846d051071571c0a6ee280542d920 141 SUPERFAMILY SSF69500 1 140 1.16E-39 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TL08_08310 6cf846d051071571c0a6ee280542d920 141 Gene3D G3DSA:3.50.80.10 1 141 3.6E-38 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TL08_08310 6cf846d051071571c0a6ee280542d920 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 141 2.3E-33 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 TL08_03650 852f3339fea47f790d7d4fa8e75ba25f 419 SUPERFAMILY SSF103473 19 395 3.66E-20 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_03650 852f3339fea47f790d7d4fa8e75ba25f 419 Pfam PF07690 Major Facilitator Superfamily 23 353 5.1E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_03650 852f3339fea47f790d7d4fa8e75ba25f 419 Gene3D G3DSA:1.20.1250.20 18 393 1.0E-15 T 12-10-2018 TL08_10895 3d527639764a668db381ab025936d878 255 Gene3D G3DSA:3.40.50.720 2 253 2.2E-46 T 12-10-2018 TL08_10895 3d527639764a668db381ab025936d878 255 SUPERFAMILY SSF51735 6 253 2.08E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_10895 3d527639764a668db381ab025936d878 255 PIRSF PIRSF000094 2 255 1.0E-86 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TL08_10895 3d527639764a668db381ab025936d878 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 1.1E-66 T 12-10-2018 TL08_14635 dd1804bb1b810964c594e4fe7c47512b 327 Pfam PF08241 Methyltransferase domain 115 209 1.8E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_14635 dd1804bb1b810964c594e4fe7c47512b 327 SUPERFAMILY SSF53335 88 221 2.34E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_14635 dd1804bb1b810964c594e4fe7c47512b 327 Gene3D G3DSA:3.40.50.150 86 244 1.2E-30 T 12-10-2018 TL08_03495 8697d3cd39132e6cc034f0e3ecd7d976 537 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 62 309 3.2E-10 T 12-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 TL08_03495 8697d3cd39132e6cc034f0e3ecd7d976 537 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 345 536 7.6E-18 T 12-10-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-7921|MetaCyc: PWY-7922|MetaCyc: PWY-7979|Reactome: R-HSA-5173105 TL08_24115 36b90fdc8ce7dde4a6642f308f21ffb4 95 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 28 92 1.7E-10 T 12-10-2018 IPR026496 Putative ATP-grasp target RiPP TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 105 125 1.7E-11 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 292 314 1.7E-11 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 448 470 1.7E-11 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 79 103 1.7E-11 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 86 151 2.2E-23 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 187 208 1.4E-56 T 12-10-2018 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 128 1.4E-56 T 12-10-2018 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 252 273 1.4E-56 T 12-10-2018 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 274 300 1.4E-56 T 12-10-2018 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 449 468 1.4E-56 T 12-10-2018 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 342 354 1.4E-56 T 12-10-2018 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 Pfam PF00361 Proton-conducting membrane transporter 164 450 3.7E-85 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02660 1b208309f8ed14c3929aaab0ce7f50c7 663 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 24 657 1.3E-219 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_06515 72eb0c9dfe4aa9796286f2dc99bff934 261 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 256 1.3E-67 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_06515 72eb0c9dfe4aa9796286f2dc99bff934 261 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_06515 72eb0c9dfe4aa9796286f2dc99bff934 261 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_06515 72eb0c9dfe4aa9796286f2dc99bff934 261 SUPERFAMILY SSF53681 7 109 3.92E-33 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_06515 72eb0c9dfe4aa9796286f2dc99bff934 261 SUPERFAMILY SSF53681 111 259 7.03E-40 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_06515 72eb0c9dfe4aa9796286f2dc99bff934 261 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 216 7.4E-33 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_06515 72eb0c9dfe4aa9796286f2dc99bff934 261 Gene3D G3DSA:3.40.50.1860 97 208 2.0E-94 T 12-10-2018 TL08_06515 72eb0c9dfe4aa9796286f2dc99bff934 261 Hamap MF_00258 Glutamate racemase [murI]. 6 259 36.628 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_06515 72eb0c9dfe4aa9796286f2dc99bff934 261 Gene3D G3DSA:3.40.50.1860 7 257 2.0E-94 T 12-10-2018 TL08_21045 fa535ebd148d140c87eb61cf7dff8c0b 142 PRINTS PR00502 NUDIX hydrolase family signature 38 52 5.2E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_21045 fa535ebd148d140c87eb61cf7dff8c0b 142 PRINTS PR00502 NUDIX hydrolase family signature 52 67 5.2E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_21045 fa535ebd148d140c87eb61cf7dff8c0b 142 Gene3D G3DSA:3.90.79.10 4 142 3.6E-41 T 12-10-2018 TL08_21045 fa535ebd148d140c87eb61cf7dff8c0b 142 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_21045 fa535ebd148d140c87eb61cf7dff8c0b 142 Pfam PF00293 NUDIX domain 9 134 6.0E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_21045 fa535ebd148d140c87eb61cf7dff8c0b 142 SUPERFAMILY SSF55811 6 138 1.62E-28 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 2.5E-49 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 Pfam PF01245 Ribosomal protein L19 4 112 2.0E-50 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.3E-41 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.3E-41 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.3E-41 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 PIRSF PIRSF002191 1 119 3.4E-51 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 Gene3D G3DSA:2.30.30.790 3 114 2.1E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 SUPERFAMILY SSF50104 1 114 3.91E-47 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TL08_08780 cc2772bc01471f8fa95e8d2f4abc899a 119 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.781 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_21335 949eb2547ed0935d03720b72ffb138d1 298 SMART SM00382 29 206 0.0017 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_21335 949eb2547ed0935d03720b72ffb138d1 298 Gene3D G3DSA:3.40.50.300 2 227 2.9E-36 T 12-10-2018 TL08_21335 949eb2547ed0935d03720b72ffb138d1 298 SUPERFAMILY SSF52540 5 220 1.49E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21335 949eb2547ed0935d03720b72ffb138d1 298 Pfam PF00005 ABC transporter 20 154 1.0E-15 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 242 1.5E-62 T 12-10-2018 TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 SUPERFAMILY SSF51735 5 243 5.18E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 8.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 8.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 8.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.1E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 Gene3D G3DSA:3.40.50.720 1 246 2.0E-81 T 12-10-2018 TL08_00490 5d96e7037be167e11c5e3150276ea1e3 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 2.0E-4 T 12-10-2018 TL08_09050 02ef7b6744791735042b6e7c7b60ecaf 144 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09050 02ef7b6744791735042b6e7c7b60ecaf 144 Gene3D G3DSA:1.10.1660.10 1 121 1.3E-26 T 12-10-2018 TL08_09050 02ef7b6744791735042b6e7c7b60ecaf 144 SUPERFAMILY SSF46955 1 112 7.69E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_09050 02ef7b6744791735042b6e7c7b60ecaf 144 SMART SM00422 1 69 2.5E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09050 02ef7b6744791735042b6e7c7b60ecaf 144 Pfam PF13411 MerR HTH family regulatory protein 1 63 3.7E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09050 02ef7b6744791735042b6e7c7b60ecaf 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.9E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09050 02ef7b6744791735042b6e7c7b60ecaf 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.9E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_09050 02ef7b6744791735042b6e7c7b60ecaf 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.9E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_00840 cbab45c32f8fb9aea016edccc2aa6293 70 Pfam PF05532 CsbD-like 5 56 7.6E-14 T 12-10-2018 IPR008462 CsbD-like domain TL08_00840 cbab45c32f8fb9aea016edccc2aa6293 70 Gene3D G3DSA:1.10.1470.10 4 66 7.9E-7 T 12-10-2018 IPR036629 YjbJ superfamily TL08_00840 cbab45c32f8fb9aea016edccc2aa6293 70 SUPERFAMILY SSF69047 5 67 8.11E-9 T 12-10-2018 IPR036629 YjbJ superfamily TL08_10365 943945c41e09c07adec0920a49f9feef 212 Gene3D G3DSA:2.70.50.50 32 212 4.6E-63 T 12-10-2018 TL08_10365 943945c41e09c07adec0920a49f9feef 212 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 209 2.4E-44 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal TL08_10365 943945c41e09c07adec0920a49f9feef 212 SUPERFAMILY SSF81296 32 212 4.34E-48 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_08685 6e52366366575764d9b3f522e0f6a145 409 Gene3D G3DSA:3.40.800.20 3 369 3.2E-105 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TL08_08685 6e52366366575764d9b3f522e0f6a145 409 SUPERFAMILY SSF52768 3 337 3.26E-100 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily TL08_08685 6e52366366575764d9b3f522e0f6a145 409 PRINTS PR01272 Acetoin utilisation ACUC protein signature 87 101 1.2E-6 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TL08_08685 6e52366366575764d9b3f522e0f6a145 409 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 1.2E-6 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TL08_08685 6e52366366575764d9b3f522e0f6a145 409 PRINTS PR01272 Acetoin utilisation ACUC protein signature 108 121 1.2E-6 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TL08_08685 6e52366366575764d9b3f522e0f6a145 409 PRINTS PR01272 Acetoin utilisation ACUC protein signature 275 291 1.2E-6 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TL08_08685 6e52366366575764d9b3f522e0f6a145 409 Pfam PF00850 Histone deacetylase domain 21 321 8.8E-76 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TL08_08685 6e52366366575764d9b3f522e0f6a145 409 PRINTS PR01270 Histone deacetylase superfamily signature 250 260 3.5E-18 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TL08_08685 6e52366366575764d9b3f522e0f6a145 409 PRINTS PR01270 Histone deacetylase superfamily signature 164 179 3.5E-18 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TL08_08685 6e52366366575764d9b3f522e0f6a145 409 PRINTS PR01270 Histone deacetylase superfamily signature 131 154 3.5E-18 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TL08_08275 ad8f9e02f6a3b2860e01b454ffd15e10 268 Pfam PF01925 Sulfite exporter TauE/SafE 22 259 9.5E-37 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TL08_18545 7fe6863faf40cfdee106dd36d9b2df8f 311 Pfam PF09339 IclR helix-turn-helix domain 70 118 4.9E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_18545 7fe6863faf40cfdee106dd36d9b2df8f 311 SUPERFAMILY SSF46785 70 135 8.61E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_18545 7fe6863faf40cfdee106dd36d9b2df8f 311 Pfam PF01614 Bacterial transcriptional regulator 194 288 2.4E-6 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_18545 7fe6863faf40cfdee106dd36d9b2df8f 311 Gene3D G3DSA:1.10.10.10 66 137 2.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18545 7fe6863faf40cfdee106dd36d9b2df8f 311 SUPERFAMILY SSF55781 124 307 1.18E-17 T 12-10-2018 TL08_18545 7fe6863faf40cfdee106dd36d9b2df8f 311 SMART SM00346 70 158 1.2E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_18545 7fe6863faf40cfdee106dd36d9b2df8f 311 Gene3D G3DSA:3.30.450.40 142 304 1.3E-16 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_16500 eeee4eb359c683f5f5a5f127297c67fa 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16500 eeee4eb359c683f5f5a5f127297c67fa 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16500 eeee4eb359c683f5f5a5f127297c67fa 187 SUPERFAMILY SSF46689 4 84 1.64E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16500 eeee4eb359c683f5f5a5f127297c67fa 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 55 4.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16500 eeee4eb359c683f5f5a5f127297c67fa 187 Gene3D G3DSA:1.10.357.10 6 186 4.6E-46 T 12-10-2018 TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 190 209 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 178 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 129 1.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 51 281 7.6E-50 T 12-10-2018 TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 177 205 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 SUPERFAMILY SSF51735 41 283 2.88E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 2.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 228 2.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 180 2.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 245 265 2.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 129 2.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 43 60 2.0E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19525 a9b1e7c1dc40b8b137132fc48facb8ed 286 Gene3D G3DSA:3.40.50.720 4 283 2.1E-77 T 12-10-2018 TL08_15080 cffa35e2cfc7eebe759aabe94dccbc2a 279 Gene3D G3DSA:3.20.20.30 5 268 6.3E-58 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_15080 cffa35e2cfc7eebe759aabe94dccbc2a 279 Pfam PF00296 Luciferase-like monooxygenase 13 203 3.9E-36 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_15080 cffa35e2cfc7eebe759aabe94dccbc2a 279 SUPERFAMILY SSF51679 4 250 3.97E-49 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_10015 c8cf5872a945c9fabf67297c1e9dd712 605 SUPERFAMILY SSF52540 357 598 7.48E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10015 c8cf5872a945c9fabf67297c1e9dd712 605 ProSitePatterns PS00211 ABC transporters family signature. 500 514 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_10015 c8cf5872a945c9fabf67297c1e9dd712 605 SUPERFAMILY SSF90123 25 334 7.59E-69 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_10015 c8cf5872a945c9fabf67297c1e9dd712 605 Gene3D G3DSA:3.40.50.300 346 600 3.4E-81 T 12-10-2018 TL08_10015 c8cf5872a945c9fabf67297c1e9dd712 605 Pfam PF00005 ABC transporter 380 526 3.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_10015 c8cf5872a945c9fabf67297c1e9dd712 605 SMART SM00382 388 580 6.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_10015 c8cf5872a945c9fabf67297c1e9dd712 605 Gene3D G3DSA:1.20.1560.10 16 337 4.7E-80 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_10015 c8cf5872a945c9fabf67297c1e9dd712 605 Pfam PF00664 ABC transporter transmembrane region 39 309 1.9E-42 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 SUPERFAMILY SSF55874 394 534 2.36E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 Pfam PF08448 PAS fold 227 320 6.4E-6 T 12-10-2018 IPR013656 PAS fold-4 TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 SUPERFAMILY SSF55890 330 397 6.67E-5 T 12-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 Pfam PF17203 Single cache domain 3 48 175 7.5E-27 T 12-10-2018 IPR033463 Single cache domain 3 TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 479 4.6E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 516 4.6E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 SMART SM00091 219 285 0.0062 T 12-10-2018 IPR000014 PAS domain TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 SUPERFAMILY SSF103190 45 173 5.49E-34 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 Gene3D G3DSA:3.30.450.20 207 318 8.8E-21 T 12-10-2018 TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 Gene3D G3DSA:3.30.450.20 40 176 1.3E-41 T 12-10-2018 TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 SUPERFAMILY SSF55785 211 316 2.66E-7 T 12-10-2018 IPR035965 PAS domain superfamily TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 SMART SM00387 423 536 5.2E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 424 534 4.4E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_17270 42289e9cf562eea4eaab7d069dcaf62d 542 Gene3D G3DSA:3.30.565.10 386 536 3.9E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_11590 618bb97e33b99fc9d55a584b675b2ae4 165 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 16 152 9.7E-47 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_11590 618bb97e33b99fc9d55a584b675b2ae4 165 SUPERFAMILY SSF52121 12 158 3.14E-49 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_11590 618bb97e33b99fc9d55a584b675b2ae4 165 Gene3D G3DSA:3.40.50.960 1 159 3.2E-52 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_11590 618bb97e33b99fc9d55a584b675b2ae4 165 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 155 25.619 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_11590 618bb97e33b99fc9d55a584b675b2ae4 165 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 150 2.0E-39 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 Gene3D G3DSA:1.10.150.240 21 101 2.8E-47 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 SUPERFAMILY SSF56784 8 227 1.08E-46 T 12-10-2018 IPR036412 HAD-like superfamily TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 Gene3D G3DSA:3.40.50.1000 10 223 2.8E-47 T 12-10-2018 IPR023214 HAD superfamily TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 200 3.8E-21 T 12-10-2018 TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 160 1.6E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 8 19 1.6E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 1.6E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 162 182 1.6E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 114 195 3.7E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_22670 de10bff4f4fcb05651a00760ca4e2a70 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 59 200 5.1E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_08270 483928f7aa454b1fc16915687c19f48e 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 2.0E-25 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08270 483928f7aa454b1fc16915687c19f48e 86 Gene3D G3DSA:1.20.58.110 1 86 2.3E-29 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08270 483928f7aa454b1fc16915687c19f48e 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 1.0E-24 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08270 483928f7aa454b1fc16915687c19f48e 86 Pfam PF01649 Ribosomal protein S20 2 84 3.0E-27 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08270 483928f7aa454b1fc16915687c19f48e 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.59 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08270 483928f7aa454b1fc16915687c19f48e 86 SUPERFAMILY SSF46992 3 86 2.35E-28 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_05835 914108664064fd77d2da3642d7088075 393 PRINTS PR00412 Epoxide hydrolase signature 365 387 2.4E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05835 914108664064fd77d2da3642d7088075 393 PRINTS PR00412 Epoxide hydrolase signature 109 127 2.4E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05835 914108664064fd77d2da3642d7088075 393 PRINTS PR00412 Epoxide hydrolase signature 195 208 2.4E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05835 914108664064fd77d2da3642d7088075 393 PRINTS PR00412 Epoxide hydrolase signature 137 152 2.4E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05835 914108664064fd77d2da3642d7088075 393 SUPERFAMILY SSF53474 8 389 1.55E-92 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05835 914108664064fd77d2da3642d7088075 393 Gene3D G3DSA:3.40.50.1820 4 392 5.0E-126 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05835 914108664064fd77d2da3642d7088075 393 Pfam PF06441 Epoxide hydrolase N terminus 13 118 9.0E-33 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 TL08_05835 914108664064fd77d2da3642d7088075 393 PIRSF PIRSF001112 2 391 5.9E-102 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 TL08_12515 9534bb521d285bb0045373a86bc41511 478 SUPERFAMILY SSF53720 6 460 3.27E-75 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_12515 9534bb521d285bb0045373a86bc41511 478 Gene3D G3DSA:3.40.309.10 230 410 3.3E-181 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_12515 9534bb521d285bb0045373a86bc41511 478 Pfam PF00171 Aldehyde dehydrogenase family 7 421 1.7E-31 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_12515 9534bb521d285bb0045373a86bc41511 478 Gene3D G3DSA:3.40.605.10 8 475 3.3E-181 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_08135 7a5ce7d74aa9ca627c06c9dadbc0c683 671 SMART SM00729 280 503 2.1E-28 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TL08_08135 7a5ce7d74aa9ca627c06c9dadbc0c683 671 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 29 636 1.9E-207 T 12-10-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM TL08_08135 7a5ce7d74aa9ca627c06c9dadbc0c683 671 SUPERFAMILY SSF102114 243 651 5.49E-50 T 12-10-2018 TL08_08135 7a5ce7d74aa9ca627c06c9dadbc0c683 671 Gene3D G3DSA:3.80.30.20 279 510 5.8E-19 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TL08_08135 7a5ce7d74aa9ca627c06c9dadbc0c683 671 Pfam PF04055 Radical SAM superfamily 284 448 7.1E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_03190 cf169215095313ba2d74b245e23842a0 180 Pfam PF04075 F420H(2)-dependent quinone reductase 48 176 4.6E-52 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_03190 cf169215095313ba2d74b245e23842a0 180 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 65 176 4.7E-36 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_03190 cf169215095313ba2d74b245e23842a0 180 Gene3D G3DSA:2.30.110.10 34 177 9.1E-55 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_10420 fbd94000baa51eb801a737da9ab25470 514 SUPERFAMILY SSF103473 215 487 1.01E-13 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_10420 fbd94000baa51eb801a737da9ab25470 514 SUPERFAMILY SSF103473 10 196 8.11E-19 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_10420 fbd94000baa51eb801a737da9ab25470 514 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 484 2.6E-77 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 TL08_10420 fbd94000baa51eb801a737da9ab25470 514 Pfam PF00854 POT family 117 456 8.6E-31 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 TL08_10420 fbd94000baa51eb801a737da9ab25470 514 Gene3D G3DSA:1.20.1250.20 7 496 5.0E-88 T 12-10-2018 TL08_24725 e46207de26f42d3793eca80d8c41bce3 465 Pfam PF04024 PspC domain 33 84 9.3E-14 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal TL08_24725 e46207de26f42d3793eca80d8c41bce3 465 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 364 459 4.2E-9 T 12-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF TL08_07305 f06ddf49e2f07a5600b1f5bda98feeda 267 Hamap MF_01393 ATP synthase subunit a [atpB]. 19 266 13.356 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07305 f06ddf49e2f07a5600b1f5bda98feeda 267 Gene3D G3DSA:1.20.120.220 90 267 2.5E-30 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07305 f06ddf49e2f07a5600b1f5bda98feeda 267 Pfam PF00119 ATP synthase A chain 42 259 2.7E-48 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07305 f06ddf49e2f07a5600b1f5bda98feeda 267 SUPERFAMILY SSF81336 93 260 2.88E-35 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07305 f06ddf49e2f07a5600b1f5bda98feeda 267 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 32 260 3.8E-42 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07305 f06ddf49e2f07a5600b1f5bda98feeda 267 PRINTS PR00123 ATP synthase A subunit signature 184 206 4.9E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07305 f06ddf49e2f07a5600b1f5bda98feeda 267 PRINTS PR00123 ATP synthase A subunit signature 246 261 4.9E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07305 f06ddf49e2f07a5600b1f5bda98feeda 267 PRINTS PR00123 ATP synthase A subunit signature 99 115 4.9E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07175 326d08d39d7845d8ac4715a5c2e0f2f2 321 SMART SM00880 28 304 2.3E-53 T 12-10-2018 IPR007899 CHAD domain TL08_07175 326d08d39d7845d8ac4715a5c2e0f2f2 321 Pfam PF05235 CHAD domain 28 270 3.6E-46 T 12-10-2018 IPR007899 CHAD domain TL08_07175 326d08d39d7845d8ac4715a5c2e0f2f2 321 Gene3D G3DSA:1.40.20.10 8 320 1.8E-60 T 12-10-2018 IPR038186 CHAD domain superfamily TL08_11555 55fad387f005c3843a02fe132241310f 730 Gene3D G3DSA:3.40.50.300 217 378 6.3E-27 T 12-10-2018 TL08_11555 55fad387f005c3843a02fe132241310f 730 Hamap MF_00983 Probable primosomal protein N' [priA]. 26 729 20.33 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 TL08_11555 55fad387f005c3843a02fe132241310f 730 SUPERFAMILY SSF52540 237 314 4.48E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11555 55fad387f005c3843a02fe132241310f 730 Gene3D G3DSA:1.10.8.630 19 131 2.2E-17 T 12-10-2018 TL08_06245 f88ea785ba94cd812abe7ce97224e5f9 316 SMART SM00342 223 306 1.6E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_06245 f88ea785ba94cd812abe7ce97224e5f9 316 Gene3D G3DSA:3.40.50.880 1 202 1.3E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_06245 f88ea785ba94cd812abe7ce97224e5f9 316 SUPERFAMILY SSF46689 259 310 1.81E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06245 f88ea785ba94cd812abe7ce97224e5f9 316 SUPERFAMILY SSF46689 209 257 1.22E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06245 f88ea785ba94cd812abe7ce97224e5f9 316 Gene3D G3DSA:1.10.10.60 207 314 6.8E-30 T 12-10-2018 TL08_06245 f88ea785ba94cd812abe7ce97224e5f9 316 SUPERFAMILY SSF52317 1 187 3.67E-43 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_06245 f88ea785ba94cd812abe7ce97224e5f9 316 Pfam PF12833 Helix-turn-helix domain 230 307 4.9E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_06245 f88ea785ba94cd812abe7ce97224e5f9 316 Pfam PF01965 DJ-1/PfpI family 3 168 5.9E-17 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TL08_07670 1a52ce9419529afabec19f884d7a2757 323 PRINTS PR00118 Beta-lactamase class A signature 98 115 1.3E-58 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_07670 1a52ce9419529afabec19f884d7a2757 323 PRINTS PR00118 Beta-lactamase class A signature 200 225 1.3E-58 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_07670 1a52ce9419529afabec19f884d7a2757 323 PRINTS PR00118 Beta-lactamase class A signature 67 91 1.3E-58 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_07670 1a52ce9419529afabec19f884d7a2757 323 PRINTS PR00118 Beta-lactamase class A signature 174 198 1.3E-58 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_07670 1a52ce9419529afabec19f884d7a2757 323 PRINTS PR00118 Beta-lactamase class A signature 138 163 1.3E-58 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_07670 1a52ce9419529afabec19f884d7a2757 323 PRINTS PR00118 Beta-lactamase class A signature 255 270 1.3E-58 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 TL08_07670 1a52ce9419529afabec19f884d7a2757 323 SUPERFAMILY SSF56601 66 320 1.62E-65 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_07670 1a52ce9419529afabec19f884d7a2757 323 Gene3D G3DSA:3.40.710.10 61 323 2.6E-72 T 12-10-2018 TL08_07670 1a52ce9419529afabec19f884d7a2757 323 Pfam PF13354 Beta-lactamase enzyme family 87 295 4.6E-33 T 12-10-2018 TL08_17440 74500bee033e1de8309f46955204dc53 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 62 325 6.5E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_22770 2f3f247a74f5637d7e8f9086d29cb493 683 Gene3D G3DSA:3.30.200.20 5 93 5.9E-21 T 12-10-2018 TL08_22770 2f3f247a74f5637d7e8f9086d29cb493 683 Pfam PF00069 Protein kinase domain 15 262 4.0E-35 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_22770 2f3f247a74f5637d7e8f9086d29cb493 683 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_22770 2f3f247a74f5637d7e8f9086d29cb493 683 SUPERFAMILY SSF56112 12 344 1.17E-60 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_22770 2f3f247a74f5637d7e8f9086d29cb493 683 Gene3D G3DSA:1.10.510.10 95 270 4.6E-40 T 12-10-2018 TL08_22770 2f3f247a74f5637d7e8f9086d29cb493 683 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 133 145 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TL08_06485 41fb8f09b0b9e75328a23e63d4630b22 341 Pfam PF03576 Peptidase family S58 11 329 1.8E-67 T 12-10-2018 IPR005321 Peptidase S58, DmpA TL08_06485 41fb8f09b0b9e75328a23e63d4630b22 341 Gene3D G3DSA:3.60.70.12 6 339 1.7E-121 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TL08_06485 41fb8f09b0b9e75328a23e63d4630b22 341 SUPERFAMILY SSF56266 5 337 1.83E-71 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TL08_23350 92cb83af23794a41e46e82e87fc4180e 78 Pfam PF03966 Trm112p-like protein 6 50 4.8E-5 T 12-10-2018 IPR005651 Trm112-like TL08_23350 92cb83af23794a41e46e82e87fc4180e 78 SUPERFAMILY SSF158997 6 61 3.53E-13 T 12-10-2018 TL08_23350 92cb83af23794a41e46e82e87fc4180e 78 Gene3D G3DSA:2.20.25.10 12 61 7.4E-12 T 12-10-2018 TL08_11340 5b3fdc7e703f3c7b8d75116d12f99ad3 602 Pfam PF04183 IucA / IucC family 153 383 3.4E-57 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 TL08_11340 5b3fdc7e703f3c7b8d75116d12f99ad3 602 Gene3D G3DSA:1.10.510.40 376 581 2.6E-10 T 12-10-2018 TL08_11340 5b3fdc7e703f3c7b8d75116d12f99ad3 602 Pfam PF06276 Ferric iron reductase FhuF-like transporter 413 574 4.4E-29 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain TL08_05525 d61bcac1f33cc153ae4c295af9d50bac 253 Gene3D G3DSA:3.40.50.1110 22 222 2.0E-16 T 12-10-2018 IPR036514 SGNH hydrolase superfamily TL08_05525 d61bcac1f33cc153ae4c295af9d50bac 253 SUPERFAMILY SSF52266 39 226 2.17E-16 T 12-10-2018 TL08_05045 144c3044799e3a1327c3449cfe2c9da2 375 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 218 328 1.2E-25 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_05045 144c3044799e3a1327c3449cfe2c9da2 375 SUPERFAMILY SSF53901 180 372 5.08E-49 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05045 144c3044799e3a1327c3449cfe2c9da2 375 Gene3D G3DSA:3.40.47.10 7 114 3.8E-6 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05045 144c3044799e3a1327c3449cfe2c9da2 375 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 127 206 3.7E-14 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_05045 144c3044799e3a1327c3449cfe2c9da2 375 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 48 4.6E-5 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_05045 144c3044799e3a1327c3449cfe2c9da2 375 SMART SM00825 Beta-ketoacyl synthase 7 367 2.9E-10 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_05045 144c3044799e3a1327c3449cfe2c9da2 375 Gene3D G3DSA:3.40.47.10 115 375 2.3E-62 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_05045 144c3044799e3a1327c3449cfe2c9da2 375 SUPERFAMILY SSF53901 5 216 2.33E-36 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_06920 dc4de2822e36ae422dcd0cc68d1b1792 197 Pfam PF11706 CGNR zinc finger 140 181 3.8E-14 T 12-10-2018 IPR021005 Zinc finger, CGNR TL08_06920 dc4de2822e36ae422dcd0cc68d1b1792 197 SUPERFAMILY SSF160904 8 180 1.44E-41 T 12-10-2018 TL08_06920 dc4de2822e36ae422dcd0cc68d1b1792 197 Pfam PF07336 Putative stress-induced transcription regulator 14 135 6.7E-19 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator TL08_06920 dc4de2822e36ae422dcd0cc68d1b1792 197 Gene3D G3DSA:1.10.3300.10 7 186 2.8E-28 T 12-10-2018 IPR023286 ABATE domain superfamily TL08_23970 a19914a2e66d8475907406ca3b314d03 212 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 96 185 9.8E-11 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal TL08_23970 a19914a2e66d8475907406ca3b314d03 212 SUPERFAMILY SSF46689 16 84 2.62E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_23970 a19914a2e66d8475907406ca3b314d03 212 SUPERFAMILY SSF48498 91 203 8.01E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_23970 a19914a2e66d8475907406ca3b314d03 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 65 3.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_23970 a19914a2e66d8475907406ca3b314d03 212 Gene3D G3DSA:1.10.357.10 14 208 2.1E-34 T 12-10-2018 TL08_10255 014855b8f2d0d9dee7b30e973e44c475 665 Pfam PF01757 Acyltransferase family 7 335 5.0E-22 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_26590 abfb8534523c6db524da4de9ed2d93d6 225 Gene3D G3DSA:3.40.50.1000 81 225 1.8E-28 T 12-10-2018 IPR023214 HAD superfamily TL08_26590 abfb8534523c6db524da4de9ed2d93d6 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 86 200 4.1E-14 T 12-10-2018 TL08_26590 abfb8534523c6db524da4de9ed2d93d6 225 SUPERFAMILY SSF56784 16 223 9.6E-31 T 12-10-2018 IPR036412 HAD-like superfamily TL08_23750 5a9ae37755fc982a56625963d8b7c990 136 Pfam PF08044 Domain of unknown function (DUF1707) 9 61 9.2E-19 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 Pfam PF00089 Trypsin 28 252 2.1E-52 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 119 133 1.7E-11 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 55 70 1.7E-11 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 208 220 1.7E-11 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 SMART SM00020 27 254 2.4E-71 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 209 220 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 65 70 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 SUPERFAMILY SSF50494 22 254 3.17E-65 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 Gene3D G3DSA:2.40.10.10 40 250 1.4E-68 T 12-10-2018 TL08_09075 f96289a7bc835144d6e31725d0e92c5d 260 Gene3D G3DSA:2.40.10.10 28 248 1.4E-68 T 12-10-2018 TL08_16080 71317fc9cf94111ea15206f29c839696 249 Gene3D G3DSA:3.40.50.720 4 249 1.3E-62 T 12-10-2018 TL08_16080 71317fc9cf94111ea15206f29c839696 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 4.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16080 71317fc9cf94111ea15206f29c839696 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 4.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16080 71317fc9cf94111ea15206f29c839696 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 4.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16080 71317fc9cf94111ea15206f29c839696 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.6E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16080 71317fc9cf94111ea15206f29c839696 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 2.6E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16080 71317fc9cf94111ea15206f29c839696 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.6E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16080 71317fc9cf94111ea15206f29c839696 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 2.6E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16080 71317fc9cf94111ea15206f29c839696 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.6E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16080 71317fc9cf94111ea15206f29c839696 249 SUPERFAMILY SSF51735 13 233 3.48E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16080 71317fc9cf94111ea15206f29c839696 249 Pfam PF00106 short chain dehydrogenase 15 207 3.0E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18500 032502d3803bf0201ebcc1cf8d680e65 130 Gene3D G3DSA:3.10.450.50 2 126 2.8E-27 T 12-10-2018 TL08_18500 032502d3803bf0201ebcc1cf8d680e65 130 Pfam PF07858 Limonene-1,2-epoxide hydrolase catalytic domain 5 123 4.8E-22 T 12-10-2018 IPR013100 Limonene-1,2-epoxide hydrolase TL08_18500 032502d3803bf0201ebcc1cf8d680e65 130 SUPERFAMILY SSF54427 4 122 7.63E-23 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_10570 653610a7f3feba3af9b32afbe40f345d 443 Gene3D G3DSA:3.50.50.60 6 383 4.0E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_10570 653610a7f3feba3af9b32afbe40f345d 443 Pfam PF01266 FAD dependent oxidoreductase 7 75 1.0E-6 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_10570 653610a7f3feba3af9b32afbe40f345d 443 SUPERFAMILY SSF51905 6 373 2.37E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_10570 653610a7f3feba3af9b32afbe40f345d 443 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 1.5E-5 T 12-10-2018 TL08_10570 653610a7f3feba3af9b32afbe40f345d 443 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 321 1.5E-5 T 12-10-2018 TL08_10570 653610a7f3feba3af9b32afbe40f345d 443 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.5E-5 T 12-10-2018 TL08_06435 99d434f76a204d8c3a777424696d0c28 683 SMART SM00487 24 308 0.0013 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_06435 99d434f76a204d8c3a777424696d0c28 683 Gene3D G3DSA:3.40.50.300 494 677 8.5E-29 T 12-10-2018 TL08_06435 99d434f76a204d8c3a777424696d0c28 683 SMART SM00491 522 651 1.0E-40 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TL08_06435 99d434f76a204d8c3a777424696d0c28 683 Gene3D G3DSA:3.40.50.300 27 289 1.1E-45 T 12-10-2018 TL08_06435 99d434f76a204d8c3a777424696d0c28 683 SMART SM00488 27 291 0.0081 T 12-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 TL08_06435 99d434f76a204d8c3a777424696d0c28 683 Pfam PF00270 DEAD/DEAH box helicase 37 93 1.2E-5 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_06435 99d434f76a204d8c3a777424696d0c28 683 SUPERFAMILY SSF52540 8 647 1.07E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06435 99d434f76a204d8c3a777424696d0c28 683 Pfam PF13307 Helicase C-terminal domain 505 664 3.8E-27 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TL08_12885 8b2fcaf09053a74199775ca8b5d05c95 293 SUPERFAMILY SSF52540 16 247 5.01E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12885 8b2fcaf09053a74199775ca8b5d05c95 293 SMART SM00382 42 235 1.6E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12885 8b2fcaf09053a74199775ca8b5d05c95 293 Pfam PF00005 ABC transporter 33 187 8.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12885 8b2fcaf09053a74199775ca8b5d05c95 293 Gene3D G3DSA:3.40.50.300 11 262 4.9E-57 T 12-10-2018 TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 Gene3D G3DSA:3.40.190.10 105 282 1.7E-21 T 12-10-2018 TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 6.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 6.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 6.1E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 Pfam PF03466 LysR substrate binding domain 102 296 9.1E-25 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 SUPERFAMILY SSF46785 13 125 4.94E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 75 2.2E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 Gene3D G3DSA:1.10.10.10 15 103 4.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 SUPERFAMILY SSF53850 103 300 4.89E-23 T 12-10-2018 TL08_16670 05e818727baef5c267cf53f3042e6e8f 304 Gene3D G3DSA:3.40.190.10 183 273 1.7E-21 T 12-10-2018 TL08_05785 b687c396ff3acc3525f7b0cd36871332 284 Gene3D G3DSA:1.10.260.40 9 74 1.1E-13 T 12-10-2018 TL08_05785 b687c396ff3acc3525f7b0cd36871332 284 SMART SM00530 16 71 4.9E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_05785 b687c396ff3acc3525f7b0cd36871332 284 SUPERFAMILY SSF47413 11 70 2.53E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_05785 b687c396ff3acc3525f7b0cd36871332 284 Pfam PF13560 Helix-turn-helix domain 12 73 1.1E-12 T 12-10-2018 TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 SUPERFAMILY SSF53850 87 295 3.8E-24 T 12-10-2018 TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 Gene3D G3DSA:1.10.10.10 1 83 1.9E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 Pfam PF03466 LysR substrate binding domain 87 290 2.4E-29 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 SUPERFAMILY SSF46785 3 85 2.0E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 6.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 6.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 6.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.9E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 Gene3D G3DSA:3.40.190.10 162 266 1.0E-29 T 12-10-2018 TL08_26630 eea918b27cb469b31154d9feaaf598aa 335 Gene3D G3DSA:3.40.190.10 94 290 1.0E-29 T 12-10-2018 TL08_23995 2fb1c8de8b16aee83b03a37a4152cc37 234 Pfam PF01899 Na+/H+ ion antiporter subunit 19 148 1.6E-24 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TL08_20250 42c3cdc7b8de95a6372f8a126374a64e 185 SUPERFAMILY SSF88659 119 176 1.57E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_20250 42c3cdc7b8de95a6372f8a126374a64e 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 176 1.8E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_20250 42c3cdc7b8de95a6372f8a126374a64e 185 Pfam PF04542 Sigma-70 region 2 24 89 3.3E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_20250 42c3cdc7b8de95a6372f8a126374a64e 185 SUPERFAMILY SSF88946 1 103 2.62E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_20250 42c3cdc7b8de95a6372f8a126374a64e 185 Gene3D G3DSA:1.10.1740.10 1 86 4.2E-32 T 12-10-2018 TL08_20250 42c3cdc7b8de95a6372f8a126374a64e 185 Pfam PF08281 Sigma-70, region 4 123 174 1.4E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_20250 42c3cdc7b8de95a6372f8a126374a64e 185 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 45 76 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_20250 42c3cdc7b8de95a6372f8a126374a64e 185 Gene3D G3DSA:1.10.10.10 116 185 5.9E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04190 8d09342272142ab2b76592d20c40381a 79 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 13 54 5.0E-13 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TL08_04190 8d09342272142ab2b76592d20c40381a 79 SUPERFAMILY SSF116842 11 69 6.93E-17 T 12-10-2018 TL08_04190 8d09342272142ab2b76592d20c40381a 79 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 16 70 2.3E-21 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TL08_04190 8d09342272142ab2b76592d20c40381a 79 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 15 75 14.063 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TL08_04190 8d09342272142ab2b76592d20c40381a 79 PIRSF PIRSF006488 2 79 2.6E-24 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TL08_04190 8d09342272142ab2b76592d20c40381a 79 Pfam PF02609 Exonuclease VII small subunit 16 67 2.8E-18 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TL08_04190 8d09342272142ab2b76592d20c40381a 79 Gene3D G3DSA:1.10.287.1040 9 79 5.2E-16 T 12-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 TL08_18950 c64850ecc2def1da9218a5748e3e1cb2 253 SUPERFAMILY SSF49879 5 99 3.16E-15 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TL08_18950 c64850ecc2def1da9218a5748e3e1cb2 253 Gene3D G3DSA:2.60.200.20 2 104 7.2E-16 T 12-10-2018 TL08_18950 c64850ecc2def1da9218a5748e3e1cb2 253 SUPERFAMILY SSF46894 186 245 5.39E-5 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_18950 c64850ecc2def1da9218a5748e3e1cb2 253 Pfam PF00498 FHA domain 26 98 3.6E-9 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TL08_18950 c64850ecc2def1da9218a5748e3e1cb2 253 Gene3D G3DSA:1.10.10.10 144 251 2.3E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_13300 588785806c5062c8466b99a4101e724a 453 Pfam PF02447 GntP family permease 7 446 4.5E-81 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TL08_23040 01a96ecc68396c981eeeefe99d41cb2f 386 TIGRFAM TIGR01224 hutI: imidazolonepropionase 24 382 4.9E-102 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23040 01a96ecc68396c981eeeefe99d41cb2f 386 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 385 41.709 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 TL08_23040 01a96ecc68396c981eeeefe99d41cb2f 386 Pfam PF01979 Amidohydrolase family 57 367 2.6E-12 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_23040 01a96ecc68396c981eeeefe99d41cb2f 386 SUPERFAMILY SSF51338 13 385 1.38E-14 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_23040 01a96ecc68396c981eeeefe99d41cb2f 386 Gene3D G3DSA:2.30.40.10 15 383 2.1E-123 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_23040 01a96ecc68396c981eeeefe99d41cb2f 386 Gene3D G3DSA:3.20.20.140 60 345 2.1E-123 T 12-10-2018 TL08_23040 01a96ecc68396c981eeeefe99d41cb2f 386 SUPERFAMILY SSF51556 59 338 1.57E-68 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_24015 5314caeef1203a968c1a2e7173dff1c8 830 Pfam PF13244 Domain of unknown function (DUF4040) 600 664 5.7E-16 T 12-10-2018 IPR025383 Domain of unknown function DUF4040 TL08_24015 5314caeef1203a968c1a2e7173dff1c8 830 Pfam PF00361 Proton-conducting membrane transporter 125 410 1.1E-63 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_24015 5314caeef1203a968c1a2e7173dff1c8 830 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 409 428 3.7E-33 T 12-10-2018 TL08_24015 5314caeef1203a968c1a2e7173dff1c8 830 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 3.7E-33 T 12-10-2018 TL08_24015 5314caeef1203a968c1a2e7173dff1c8 830 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 212 233 3.7E-33 T 12-10-2018 TL08_24015 5314caeef1203a968c1a2e7173dff1c8 830 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 302 314 3.7E-33 T 12-10-2018 TL08_24015 5314caeef1203a968c1a2e7173dff1c8 830 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 102 122 3.7E-33 T 12-10-2018 TL08_24015 5314caeef1203a968c1a2e7173dff1c8 830 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 234 260 3.7E-33 T 12-10-2018 TL08_20135 78d02d07f7bfef280990839af207ac90 381 Pfam PF09344 CT1975-like protein 9 342 6.9E-102 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 TL08_20135 78d02d07f7bfef280990839af207ac90 381 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 8 333 1.8E-92 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 TL08_15840 84bd0ac4d32a3f67b34f3a5b49308530 457 Pfam PF00155 Aminotransferase class I and II 90 447 2.5E-18 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_15840 84bd0ac4d32a3f67b34f3a5b49308530 457 Gene3D G3DSA:3.40.640.10 124 345 8.7E-73 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_15840 84bd0ac4d32a3f67b34f3a5b49308530 457 SMART SM00345 2 52 2.5E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_15840 84bd0ac4d32a3f67b34f3a5b49308530 457 SUPERFAMILY SSF53383 85 451 3.83E-66 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_15840 84bd0ac4d32a3f67b34f3a5b49308530 457 SUPERFAMILY SSF46785 7 56 4.43E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_15840 84bd0ac4d32a3f67b34f3a5b49308530 457 Gene3D G3DSA:3.90.1150.10 89 451 8.7E-73 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_15840 84bd0ac4d32a3f67b34f3a5b49308530 457 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 52 2.2E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_15840 84bd0ac4d32a3f67b34f3a5b49308530 457 Gene3D G3DSA:1.10.10.10 4 62 3.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_24700 8bfc7e742669f8f445a1a5bf7f733212 62 Pfam PF04149 Domain of unknown function (DUF397) 7 57 3.5E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_10800 4ce179178bc25a72a7c716f967754605 415 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 15 409 29.952 T 12-10-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TL08_10800 4ce179178bc25a72a7c716f967754605 415 TIGRFAM TIGR03444 EgtA_Cys_ligase: ergothioneine biosynthesis glutamate--cysteine ligase EgtA 27 402 3.6E-113 T 12-10-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TL08_10800 4ce179178bc25a72a7c716f967754605 415 SUPERFAMILY SSF55931 31 352 2.06E-33 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TL08_10800 4ce179178bc25a72a7c716f967754605 415 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 41 336 2.8E-50 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TL08_10800 4ce179178bc25a72a7c716f967754605 415 PIRSF PIRSF017901 3 411 4.2E-89 T 12-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 TL08_10800 4ce179178bc25a72a7c716f967754605 415 Gene3D G3DSA:3.30.590.20 4 410 4.7E-90 T 12-10-2018 TL08_06810 67219a41d7ee5cda2e8d3f3406560531 126 Gene3D G3DSA:3.10.180.10 1 126 5.6E-32 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_06810 67219a41d7ee5cda2e8d3f3406560531 126 SUPERFAMILY SSF54593 7 125 1.51E-9 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_17895 479e0c240a910e445523d8d6ae6b7fff 329 SUPERFAMILY SSF81345 5 324 1.27E-72 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_17895 479e0c240a910e445523d8d6ae6b7fff 329 Pfam PF01032 FecCD transport family 8 324 1.0E-83 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_17895 479e0c240a910e445523d8d6ae6b7fff 329 Gene3D G3DSA:1.10.3470.10 1 329 2.5E-90 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_24275 74ca793acb69241c671d65148ace441e 201 Pfam PF14487 Domain of unknown function (DUF4433) 2 201 4.2E-52 T 12-10-2018 IPR029494 Domain of unknown function DUF4433 TL08_09190 6f8c545836f87f45c2b6df1b1d3cc46f 185 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 5 113 23.409 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TL08_09190 6f8c545836f87f45c2b6df1b1d3cc46f 185 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 12-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 TL08_09190 6f8c545836f87f45c2b6df1b1d3cc46f 185 Pfam PF02033 Ribosome-binding factor A 6 113 1.3E-24 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TL08_09190 6f8c545836f87f45c2b6df1b1d3cc46f 185 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 4.0E-24 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TL08_09190 6f8c545836f87f45c2b6df1b1d3cc46f 185 Gene3D G3DSA:3.30.300.20 2 106 1.3E-24 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TL08_09190 6f8c545836f87f45c2b6df1b1d3cc46f 185 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 5 114 2.2E-18 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TL08_09190 6f8c545836f87f45c2b6df1b1d3cc46f 185 SUPERFAMILY SSF89919 3 116 3.53E-26 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily TL08_20460 ca012326da8b3c2ebfa3ace5b6fe3ebe 256 Gene3D G3DSA:3.40.430.10 8 254 5.1E-66 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_20460 ca012326da8b3c2ebfa3ace5b6fe3ebe 256 Pfam PF01872 RibD C-terminal domain 35 230 3.4E-33 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TL08_20460 ca012326da8b3c2ebfa3ace5b6fe3ebe 256 SUPERFAMILY SSF53597 33 248 6.15E-44 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_25660 9c2f8bfb795f82fac4c7596c29cc3413 389 Gene3D G3DSA:3.40.50.720 273 364 8.2E-22 T 12-10-2018 TL08_25660 9c2f8bfb795f82fac4c7596c29cc3413 389 Gene3D G3DSA:3.40.50.150 79 219 1.3E-8 T 12-10-2018 TL08_25660 9c2f8bfb795f82fac4c7596c29cc3413 389 Pfam PF08421 Putative zinc binding domain 9 61 9.6E-14 T 12-10-2018 IPR013630 Methyltransferase putative zinc binding domain TL08_25660 9c2f8bfb795f82fac4c7596c29cc3413 389 Pfam PF08484 C-methyltransferase C-terminal domain 213 363 9.7E-29 T 12-10-2018 IPR013691 C-methyltransferase TL08_25660 9c2f8bfb795f82fac4c7596c29cc3413 389 Gene3D G3DSA:2.20.25.520 2 59 7.2E-14 T 12-10-2018 IPR038576 Methyltransferase putative zinc binding domain superfamily TL08_25660 9c2f8bfb795f82fac4c7596c29cc3413 389 SUPERFAMILY SSF53335 92 218 1.07E-9 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_12080 1b2395a839e30cbda0c6dbe5be142fe3 499 SUPERFAMILY SSF48317 18 179 2.09E-36 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TL08_12080 1b2395a839e30cbda0c6dbe5be142fe3 499 Pfam PF00781 Diacylglycerol kinase catalytic domain 204 321 7.0E-14 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TL08_12080 1b2395a839e30cbda0c6dbe5be142fe3 499 Gene3D G3DSA:1.20.144.10 99 186 1.6E-17 T 12-10-2018 TL08_12080 1b2395a839e30cbda0c6dbe5be142fe3 499 SMART SM00014 67 176 6.2E-23 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TL08_12080 1b2395a839e30cbda0c6dbe5be142fe3 499 Gene3D G3DSA:2.60.200.40 322 481 3.5E-18 T 12-10-2018 TL08_12080 1b2395a839e30cbda0c6dbe5be142fe3 499 SMART SM00046 203 331 4.4E-12 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TL08_12080 1b2395a839e30cbda0c6dbe5be142fe3 499 Gene3D G3DSA:3.40.50.10330 201 321 4.1E-15 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TL08_12080 1b2395a839e30cbda0c6dbe5be142fe3 499 SUPERFAMILY SSF111331 204 492 1.42E-45 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TL08_12080 1b2395a839e30cbda0c6dbe5be142fe3 499 Pfam PF01569 PAP2 superfamily 68 180 3.9E-19 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TL08_22625 9fd5e4ca6d880cf1153ece2882d4a811 220 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 5 212 21.485 T 12-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 TL08_22625 9fd5e4ca6d880cf1153ece2882d4a811 220 Gene3D G3DSA:3.90.550.10 3 178 5.4E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_22625 9fd5e4ca6d880cf1153ece2882d4a811 220 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 7 204 1.2E-41 T 12-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 TL08_22625 9fd5e4ca6d880cf1153ece2882d4a811 220 SUPERFAMILY SSF53448 17 208 1.22E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_22625 9fd5e4ca6d880cf1153ece2882d4a811 220 Pfam PF01983 Guanylyl transferase CofC like 7 152 2.3E-7 T 12-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 TL08_04630 6f7d81e3d678b56388299016a392ea26 393 SUPERFAMILY SSF53756 12 389 1.08E-82 T 12-10-2018 TL08_04630 6f7d81e3d678b56388299016a392ea26 393 Gene3D G3DSA:3.40.50.2000 177 366 3.2E-78 T 12-10-2018 TL08_04630 6f7d81e3d678b56388299016a392ea26 393 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 6 385 1.6E-176 T 12-10-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 KEGG: 00500+2.4.1.342|MetaCyc: PWY-7900 TL08_04630 6f7d81e3d678b56388299016a392ea26 393 Pfam PF00534 Glycosyl transferases group 1 196 365 5.9E-29 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_04630 6f7d81e3d678b56388299016a392ea26 393 Pfam PF13439 Glycosyltransferase Family 4 19 180 2.8E-30 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_04630 6f7d81e3d678b56388299016a392ea26 393 Gene3D G3DSA:3.40.50.2000 10 383 3.2E-78 T 12-10-2018 TL08_19910 8e9845dd7846fb38c6feeaff6fd01895 323 Pfam PF04198 Putative sugar-binding domain 73 321 2.5E-57 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 TL08_19910 8e9845dd7846fb38c6feeaff6fd01895 323 Gene3D G3DSA:3.40.50.1360 67 323 1.2E-69 T 12-10-2018 TL08_19910 8e9845dd7846fb38c6feeaff6fd01895 323 SUPERFAMILY SSF100950 74 320 8.37E-57 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_19910 8e9845dd7846fb38c6feeaff6fd01895 323 Gene3D G3DSA:1.10.10.60 16 64 6.9E-12 T 12-10-2018 TL08_01535 7296defc0abd29f37adb0855cabae484 62 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 52 3.1E-12 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TL08_01535 7296defc0abd29f37adb0855cabae484 62 Pfam PF12728 Helix-turn-helix domain 5 51 4.4E-11 T 12-10-2018 TL08_26005 e9eeb6b266766d46c36c139ed3791987 63 Pfam PF04149 Domain of unknown function (DUF397) 7 58 1.3E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_01015 f7d00013b48a3966c32965332a08936c 157 SMART SM00347 37 140 6.0E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_01015 f7d00013b48a3966c32965332a08936c 157 SUPERFAMILY SSF46785 11 151 6.02E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_01015 f7d00013b48a3966c32965332a08936c 157 Pfam PF01047 MarR family 44 102 3.7E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_01015 f7d00013b48a3966c32965332a08936c 157 Gene3D G3DSA:1.10.10.10 10 153 2.0E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_20445 e5079f13a587372436991a10164f2fb0 272 SUPERFAMILY SSF52266 29 250 4.0E-61 T 12-10-2018 TL08_20445 e5079f13a587372436991a10164f2fb0 272 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 35 249 5.6E-24 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain TL08_20445 e5079f13a587372436991a10164f2fb0 272 Gene3D G3DSA:3.40.50.1110 31 258 3.2E-75 T 12-10-2018 IPR036514 SGNH hydrolase superfamily TL08_08360 bb39885fa7b6fd65c3fb48426dadf2ea 259 Pfam PF00005 ABC transporter 23 174 4.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_08360 bb39885fa7b6fd65c3fb48426dadf2ea 259 SUPERFAMILY SSF52540 5 234 2.87E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08360 bb39885fa7b6fd65c3fb48426dadf2ea 259 SMART SM00382 32 230 4.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_08360 bb39885fa7b6fd65c3fb48426dadf2ea 259 Gene3D G3DSA:3.40.50.300 5 246 5.8E-61 T 12-10-2018 TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 SUPERFAMILY SSF52540 24 794 7.72E-106 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 Pfam PF00580 UvrD/REP helicase N-terminal domain 27 344 2.2E-45 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 Pfam PF12705 PD-(D/E)XK nuclease superfamily 927 1081 1.1E-12 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 Gene3D G3DSA:3.90.320.10 905 1061 6.4E-6 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 Pfam PF13361 UvrD-like helicase C-terminal domain 431 515 9.4E-7 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 Gene3D G3DSA:3.40.50.300 23 203 5.5E-31 T 12-10-2018 TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 Pfam PF13361 UvrD-like helicase C-terminal domain 616 769 1.3E-15 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 Gene3D G3DSA:3.40.50.300 239 380 1.4E-30 T 12-10-2018 TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 Gene3D G3DSA:3.40.50.300 414 509 3.5E-15 T 12-10-2018 TL08_04825 f15f4cc92b7a3c8a6b1394ecd7372ea4 1107 SUPERFAMILY SSF52980 928 1074 1.13E-7 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TL08_22765 468b266b4446a413a838d79ab7ccb319 709 Gene3D G3DSA:1.10.510.10 95 273 3.6E-41 T 12-10-2018 TL08_22765 468b266b4446a413a838d79ab7ccb319 709 Pfam PF00069 Protein kinase domain 16 262 1.9E-33 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_22765 468b266b4446a413a838d79ab7ccb319 709 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_22765 468b266b4446a413a838d79ab7ccb319 709 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 133 145 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TL08_22765 468b266b4446a413a838d79ab7ccb319 709 SUPERFAMILY SSF56112 11 267 4.18E-58 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_22765 468b266b4446a413a838d79ab7ccb319 709 Gene3D G3DSA:3.30.200.20 5 93 4.4E-17 T 12-10-2018 TL08_22575 530b78797d364c43e16c88b2efc373f8 301 SMART SM00382 29 205 6.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_22575 530b78797d364c43e16c88b2efc373f8 301 SUPERFAMILY SSF52540 4 220 3.85E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_22575 530b78797d364c43e16c88b2efc373f8 301 Pfam PF00005 ABC transporter 20 157 1.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_22575 530b78797d364c43e16c88b2efc373f8 301 Gene3D G3DSA:3.40.50.300 1 238 2.9E-60 T 12-10-2018 TL08_22265 6dae2d7359db70da09426aebaddc262d 354 Gene3D G3DSA:2.30.30.240 2 82 9.6E-8 T 12-10-2018 TL08_22265 6dae2d7359db70da09426aebaddc262d 354 Pfam PF05239 PRC-barrel domain 9 76 6.0E-8 T 12-10-2018 IPR027275 PRC-barrel domain TL08_22265 6dae2d7359db70da09426aebaddc262d 354 SUPERFAMILY SSF50346 8 113 1.67E-18 T 12-10-2018 IPR011033 PRC-barrel-like superfamily TL08_22265 6dae2d7359db70da09426aebaddc262d 354 Pfam PF09557 Domain of unknown function (DUF2382) 230 341 4.0E-26 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 TL08_15380 fe84ae23216a5c2b451f6cd2ff36afe4 249 Gene3D G3DSA:1.20.120.450 2 135 3.5E-6 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_15380 fe84ae23216a5c2b451f6cd2ff36afe4 249 SUPERFAMILY SSF109854 1 137 1.79E-12 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_15380 fe84ae23216a5c2b451f6cd2ff36afe4 249 Pfam PF07398 MDMPI C-terminal domain 145 242 3.8E-12 T 12-10-2018 IPR010872 MDMPI C-terminal TL08_15380 fe84ae23216a5c2b451f6cd2ff36afe4 249 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 10 131 1.2E-22 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 TL08_15380 fe84ae23216a5c2b451f6cd2ff36afe4 249 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 225 8.9E-24 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type TL08_02280 abedd7a5946fc10de7b4bc33940e0871 441 SUPERFAMILY SSF53756 35 422 1.57E-81 T 12-10-2018 TL08_02280 abedd7a5946fc10de7b4bc33940e0871 441 Gene3D G3DSA:3.40.50.2000 214 403 1.9E-123 T 12-10-2018 TL08_02280 abedd7a5946fc10de7b4bc33940e0871 441 Pfam PF13439 Glycosyltransferase Family 4 37 217 5.7E-29 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_02280 abedd7a5946fc10de7b4bc33940e0871 441 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 17 427 50.834 T 12-10-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 TL08_02280 abedd7a5946fc10de7b4bc33940e0871 441 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 18 424 6.3E-188 T 12-10-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 TL08_02280 abedd7a5946fc10de7b4bc33940e0871 441 Pfam PF00534 Glycosyl transferases group 1 228 386 3.7E-33 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_02280 abedd7a5946fc10de7b4bc33940e0871 441 Gene3D G3DSA:3.40.50.2000 22 419 1.9E-123 T 12-10-2018 TL08_17975 dc5690a8a0e7605a6b5468ccd1b28452 284 SUPERFAMILY SSF51735 2 224 7.14E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_17975 dc5690a8a0e7605a6b5468ccd1b28452 284 Pfam PF13460 NAD(P)H-binding 6 177 1.5E-20 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_17975 dc5690a8a0e7605a6b5468ccd1b28452 284 Gene3D G3DSA:3.40.50.720 5 264 5.0E-72 T 12-10-2018 TL08_17975 dc5690a8a0e7605a6b5468ccd1b28452 284 Gene3D G3DSA:3.90.25.10 137 271 5.0E-72 T 12-10-2018 TL08_20115 15f82de3cdcc862f2e779fce979ca97f 215 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 7 202 2.2E-32 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 TL08_20115 15f82de3cdcc862f2e779fce979ca97f 215 Gene3D G3DSA:1.10.3630.10 5 208 1.8E-9 T 12-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 125 141 - T 12-10-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 PRINTS PR00733 Glycosyl hydrolase family 6 signature 69 88 2.5E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 PRINTS PR00733 Glycosyl hydrolase family 6 signature 328 341 2.5E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 PRINTS PR00733 Glycosyl hydrolase family 6 signature 392 406 2.5E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 PRINTS PR00733 Glycosyl hydrolase family 6 signature 224 237 2.5E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 PRINTS PR00733 Glycosyl hydrolase family 6 signature 369 389 2.5E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 PRINTS PR00733 Glycosyl hydrolase family 6 signature 152 167 2.5E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 PRINTS PR00733 Glycosyl hydrolase family 6 signature 264 274 2.5E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 PRINTS PR00733 Glycosyl hydrolase family 6 signature 120 133 2.5E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 PIRSF PIRSF001100 3 466 1.0E-103 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 Pfam PF01341 Glycosyl hydrolases family 6 71 415 1.5E-88 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 SUPERFAMILY SSF51989 49 466 1.7E-97 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 TL08_06795 adf10c4802f539d855a3d680c9aebb9e 467 Gene3D G3DSA:3.20.20.40 49 466 2.2E-166 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 SUPERFAMILY SSF53474 3 285 5.88E-72 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 Gene3D G3DSA:3.40.50.1820 1 287 1.7E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 Pfam PF00561 alpha/beta hydrolase fold 27 270 7.3E-34 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 PRINTS PR00412 Epoxide hydrolase signature 228 244 2.0E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 PRINTS PR00412 Epoxide hydrolase signature 99 112 2.0E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 PRINTS PR00412 Epoxide hydrolase signature 113 126 2.0E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 PRINTS PR00412 Epoxide hydrolase signature 33 51 2.0E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 PRINTS PR00412 Epoxide hydrolase signature 260 282 2.0E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.7E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_19220 394a3fe0a2d71dc110600b24bfb9fe59 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 1.7E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_26870 13650e09d801abe3cef2443f1251f402 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 4.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_26870 13650e09d801abe3cef2443f1251f402 188 SUPERFAMILY SSF48498 68 179 6.92E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_26870 13650e09d801abe3cef2443f1251f402 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 13 43 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_26870 13650e09d801abe3cef2443f1251f402 188 Gene3D G3DSA:1.10.10.60 1 54 1.3E-16 T 12-10-2018 TL08_26870 13650e09d801abe3cef2443f1251f402 188 Gene3D G3DSA:1.10.357.10 55 184 4.9E-26 T 12-10-2018 TL08_26870 13650e09d801abe3cef2443f1251f402 188 Pfam PF16925 Bacterial transcriptional repressor C-terminal 70 175 1.6E-6 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TL08_26870 13650e09d801abe3cef2443f1251f402 188 SUPERFAMILY SSF46689 2 72 1.33E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_03415 2939298783478fd71c2646ac187a3ec8 198 Gene3D G3DSA:1.10.357.10 4 196 3.7E-27 T 12-10-2018 TL08_03415 2939298783478fd71c2646ac187a3ec8 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_03415 2939298783478fd71c2646ac187a3ec8 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_03415 2939298783478fd71c2646ac187a3ec8 198 SUPERFAMILY SSF46689 4 67 1.05E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_03415 2939298783478fd71c2646ac187a3ec8 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.1E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_09455 9ce9d7437835b339896d7e71cda1118b 614 Gene3D G3DSA:3.30.450.330 258 592 1.5E-102 T 12-10-2018 TL08_09455 9ce9d7437835b339896d7e71cda1118b 614 Pfam PF03717 Penicillin-binding Protein dimerisation domain 76 224 7.9E-11 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TL08_09455 9ce9d7437835b339896d7e71cda1118b 614 SUPERFAMILY SSF56601 257 599 2.04E-91 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_09455 9ce9d7437835b339896d7e71cda1118b 614 Gene3D G3DSA:3.90.1310.30 69 256 2.3E-28 T 12-10-2018 TL08_09455 9ce9d7437835b339896d7e71cda1118b 614 Pfam PF00905 Penicillin binding protein transpeptidase domain 282 590 5.3E-79 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TL08_09455 9ce9d7437835b339896d7e71cda1118b 614 Gene3D G3DSA:3.40.710.10 318 511 1.5E-102 T 12-10-2018 TL08_09455 9ce9d7437835b339896d7e71cda1118b 614 SUPERFAMILY SSF56519 74 256 3.53E-27 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TL08_22740 d6702e4f44ef79f37a338f97c273eb87 183 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 39 110 1.0E-5 T 12-10-2018 IPR020535 Low molecular weight antigen Cfp6 TL08_22740 d6702e4f44ef79f37a338f97c273eb87 183 Pfam PF10756 Bacterial PH domain 42 112 3.4E-11 T 12-10-2018 IPR019692 Protein of unknown function DUF2581 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 Gene3D G3DSA:1.10.1520.10 1 147 4.4E-45 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 ProSitePatterns PS00517 Ribonuclease III family signature. 34 42 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 Pfam PF14622 Ribonuclease-III-like 12 137 2.4E-36 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 Gene3D G3DSA:3.30.160.20 154 223 2.5E-20 T 12-10-2018 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 SUPERFAMILY SSF69065 11 156 6.8E-43 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 SMART SM00535 12 148 9.9E-52 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 SUPERFAMILY SSF54768 108 220 1.73E-25 T 12-10-2018 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 Pfam PF00035 Double-stranded RNA binding motif 155 220 6.0E-16 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 12 220 9.1E-69 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 Hamap MF_00104 Ribonuclease 3 [rnc]. 1 217 29.381 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 TL08_22385 e460c4a7d9dc0aa9b04048627a528151 243 SMART SM00358 155 221 2.9E-22 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain TL08_14705 8d2566346dade7eeb30be07d036002e9 541 Pfam PF12831 FAD dependent oxidoreductase 11 513 5.8E-112 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal TL08_14705 8d2566346dade7eeb30be07d036002e9 541 SUPERFAMILY SSF51905 5 503 2.77E-21 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14705 8d2566346dade7eeb30be07d036002e9 541 Gene3D G3DSA:3.50.50.60 1 95 1.4E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05415 d78335d0de320721567ece6ee81369ce 191 SUPERFAMILY SSF46689 12 92 6.16E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_05415 d78335d0de320721567ece6ee81369ce 191 Gene3D G3DSA:1.10.357.10 3 191 2.9E-39 T 12-10-2018 TL08_05415 d78335d0de320721567ece6ee81369ce 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 3.0E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_01090 d97e0bbf94db12b3e0f7c7d9815bdcf2 336 SUPERFAMILY SSF161098 92 319 8.76E-21 T 12-10-2018 IPR035906 MetI-like superfamily TL08_01090 d97e0bbf94db12b3e0f7c7d9815bdcf2 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 334 9.5E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 SUPERFAMILY SSF48264 12 392 2.62E-97 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00359 B-class P450 signature 184 206 1.2E-52 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00359 B-class P450 signature 283 310 1.2E-52 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00359 B-class P450 signature 146 161 1.2E-52 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00359 B-class P450 signature 129 145 1.2E-52 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00359 B-class P450 signature 83 94 1.2E-52 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00359 B-class P450 signature 332 341 1.2E-52 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00359 B-class P450 signature 265 276 1.2E-52 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00359 B-class P450 signature 341 352 1.2E-52 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00359 B-class P450 signature 311 326 1.2E-52 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 Pfam PF00067 Cytochrome P450 262 361 1.4E-19 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00385 P450 superfamily signature 332 341 2.3E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00385 P450 superfamily signature 230 247 2.3E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00385 P450 superfamily signature 265 276 2.3E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 PRINTS PR00385 P450 superfamily signature 341 352 2.3E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_15905 839ed23ad78e45742c83a18b06438c12 393 Gene3D G3DSA:1.10.630.10 4 393 2.0E-135 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18825 fd1ef0fc823ee9371287dfe2d9885cde 82 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 41 56 2.0E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_18825 fd1ef0fc823ee9371287dfe2d9885cde 82 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 56 72 2.0E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_18825 fd1ef0fc823ee9371287dfe2d9885cde 82 Gene3D G3DSA:1.10.10.60 1 31 5.9E-6 T 12-10-2018 TL08_18825 fd1ef0fc823ee9371287dfe2d9885cde 82 Gene3D G3DSA:1.10.10.60 32 80 6.1E-12 T 12-10-2018 TL08_18825 fd1ef0fc823ee9371287dfe2d9885cde 82 SMART SM00342 1 72 2.3E-15 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_18825 fd1ef0fc823ee9371287dfe2d9885cde 82 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 26 68 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TL08_18825 fd1ef0fc823ee9371287dfe2d9885cde 82 SUPERFAMILY SSF46689 25 75 2.06E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18825 fd1ef0fc823ee9371287dfe2d9885cde 82 Pfam PF12833 Helix-turn-helix domain 2 73 8.1E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_17265 e0a79bdd601392b05586d1a75a34fbaf 224 SMART SM00448 2 115 8.8E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_17265 e0a79bdd601392b05586d1a75a34fbaf 224 Gene3D G3DSA:3.40.50.2300 1 137 3.7E-29 T 12-10-2018 TL08_17265 e0a79bdd601392b05586d1a75a34fbaf 224 SUPERFAMILY SSF46785 164 211 2.4E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17265 e0a79bdd601392b05586d1a75a34fbaf 224 Gene3D G3DSA:1.10.10.10 159 214 2.5E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17265 e0a79bdd601392b05586d1a75a34fbaf 224 Pfam PF00072 Response regulator receiver domain 4 115 2.1E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_17265 e0a79bdd601392b05586d1a75a34fbaf 224 SUPERFAMILY SSF52172 1 141 4.98E-33 T 12-10-2018 IPR011006 CheY-like superfamily TL08_17265 e0a79bdd601392b05586d1a75a34fbaf 224 Pfam PF08279 HTH domain 168 202 1.6E-4 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TL08_17265 e0a79bdd601392b05586d1a75a34fbaf 224 PIRSF PIRSF006171 1 224 6.8E-71 T 12-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 TL08_09800 2012eecb3a1073f4e44270b3d70540b4 353 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 267 2.0E-44 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TL08_09800 2012eecb3a1073f4e44270b3d70540b4 353 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 276 15.65 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TL08_09800 2012eecb3a1073f4e44270b3d70540b4 353 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 270 2.0E-66 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TL08_09800 2012eecb3a1073f4e44270b3d70540b4 353 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TL08_25635 9d00048da4cef9908bfef229cc150bfd 283 Gene3D G3DSA:3.90.550.10 25 276 2.7E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_25635 9d00048da4cef9908bfef229cc150bfd 283 Pfam PF00535 Glycosyl transferase family 2 66 178 1.0E-18 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_25635 9d00048da4cef9908bfef229cc150bfd 283 SUPERFAMILY SSF53448 64 263 1.53E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 Pfam PF12697 Alpha/beta hydrolase family 28 257 9.4E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 SUPERFAMILY SSF53474 4 264 6.64E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 7.1E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 7.1E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 7.1E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 7.1E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 PRINTS PR00412 Epoxide hydrolase signature 51 66 2.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 PRINTS PR00412 Epoxide hydrolase signature 94 107 2.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 PRINTS PR00412 Epoxide hydrolase signature 240 262 2.5E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_14195 2a70f49c2f8df88a242556937a7bf3cb 271 Gene3D G3DSA:3.40.50.1820 5 265 2.8E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07710 639198adcbda80222839794afb910359 323 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 21 314 5.1E-94 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TL08_07710 639198adcbda80222839794afb910359 323 Pfam PF00005 ABC transporter 29 172 3.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_07710 639198adcbda80222839794afb910359 323 Gene3D G3DSA:3.40.50.300 9 248 3.1E-62 T 12-10-2018 TL08_07710 639198adcbda80222839794afb910359 323 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_07710 639198adcbda80222839794afb910359 323 SUPERFAMILY SSF52540 13 236 2.11E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07710 639198adcbda80222839794afb910359 323 SMART SM00382 38 229 1.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23410 caa9f964b087df4661f2733db5bf9311 376 Pfam PF13439 Glycosyltransferase Family 4 16 172 2.3E-11 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_23410 caa9f964b087df4661f2733db5bf9311 376 Pfam PF00534 Glycosyl transferases group 1 194 348 3.3E-26 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_23410 caa9f964b087df4661f2733db5bf9311 376 SUPERFAMILY SSF53756 9 365 2.29E-62 T 12-10-2018 TL08_23410 caa9f964b087df4661f2733db5bf9311 376 Gene3D G3DSA:3.40.50.2000 13 362 7.8E-52 T 12-10-2018 TL08_23410 caa9f964b087df4661f2733db5bf9311 376 Gene3D G3DSA:3.40.50.2000 171 350 7.8E-52 T 12-10-2018 TL08_11290 5bfb08899f67a5cf8d0c518ef1d02f63 332 Gene3D G3DSA:1.10.600.10 12 320 1.0E-61 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_11290 5bfb08899f67a5cf8d0c518ef1d02f63 332 SUPERFAMILY SSF48576 30 288 2.27E-39 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 Gene3D G3DSA:3.40.50.720 2 153 5.6E-46 T 12-10-2018 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 151 1.6E-35 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 Gene3D G3DSA:3.90.110.10 154 317 2.8E-50 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 156 311 1.2E-17 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 SUPERFAMILY SSF56327 153 311 3.6E-45 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 SUPERFAMILY SSF51735 4 151 7.11E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 PRINTS PR00086 L-lactate dehydrogenase signature 149 167 1.5E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 PRINTS PR00086 L-lactate dehydrogenase signature 179 192 1.5E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 PRINTS PR00086 L-lactate dehydrogenase signature 125 145 1.5E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 PRINTS PR00086 L-lactate dehydrogenase signature 6 30 1.5E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 PRINTS PR00086 L-lactate dehydrogenase signature 31 55 1.5E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TL08_24505 61686e7bbc6f1968b19b412c99f80f89 318 PIRSF PIRSF000102 1 318 5.1E-91 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TL08_10855 653f474e01df0ef7658dcbe1721e1506 395 Gene3D G3DSA:3.40.50.2000 213 372 1.3E-127 T 12-10-2018 TL08_10855 653f474e01df0ef7658dcbe1721e1506 395 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 223 359 9.4E-18 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 TL08_10855 653f474e01df0ef7658dcbe1721e1506 395 SUPERFAMILY SSF53756 4 387 5.5E-71 T 12-10-2018 TL08_10855 653f474e01df0ef7658dcbe1721e1506 395 Gene3D G3DSA:3.40.50.2000 5 384 1.3E-127 T 12-10-2018 TL08_10855 653f474e01df0ef7658dcbe1721e1506 395 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 10 387 2.4E-109 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 TL08_13400 d34b5611998739358b7b14a3c0326182 764 Gene3D G3DSA:2.70.98.50 17 284 2.7E-232 T 12-10-2018 TL08_13400 d34b5611998739358b7b14a3c0326182 764 Gene3D G3DSA:1.50.10.10 12 707 2.7E-232 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_13400 d34b5611998739358b7b14a3c0326182 764 SUPERFAMILY SSF48208 254 714 2.55E-77 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_13400 d34b5611998739358b7b14a3c0326182 764 Gene3D G3DSA:2.60.40.1180 285 754 2.7E-232 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_13400 d34b5611998739358b7b14a3c0326182 764 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 3 240 1.0E-59 T 12-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 TL08_13400 d34b5611998739358b7b14a3c0326182 764 PIRSF PIRSF007663 1 741 5.2E-225 T 12-10-2018 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 Pfam PF01256 Carbohydrate kinase 243 463 6.4E-50 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 PIRSF PIRSF017184 3 480 8.9E-93 T 12-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 208 19.217 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 Pfam PF03853 YjeF-related protein N-terminus 24 187 3.5E-36 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 234 476 9.6E-44 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 5 207 2.8E-27 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 SUPERFAMILY SSF53613 219 476 1.1E-53 T 12-10-2018 IPR029056 Ribokinase-like TL08_24870 2e535183ff7effb60143725038ebcd6f 483 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 419 429 - T 12-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site TL08_24870 2e535183ff7effb60143725038ebcd6f 483 SUPERFAMILY SSF64153 4 241 1.96E-45 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 Gene3D G3DSA:3.40.50.10260 3 213 2.3E-48 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 220 481 18.967 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TL08_24870 2e535183ff7effb60143725038ebcd6f 483 Gene3D G3DSA:3.40.1190.20 218 482 1.1E-71 T 12-10-2018 IPR029056 Ribokinase-like TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 Pfam PF07729 FCD domain 93 214 2.2E-20 T 12-10-2018 IPR011711 GntR, C-terminal TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 SMART SM00345 7 66 1.1E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 3.3E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 SUPERFAMILY SSF48008 89 222 4.97E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 4.7E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 4.7E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 Gene3D G3DSA:1.20.120.530 88 224 1.5E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 Gene3D G3DSA:1.10.10.10 2 71 6.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 SMART SM00895 93 215 7.8E-16 T 12-10-2018 IPR011711 GntR, C-terminal TL08_02030 30a6d1075b0fed0e6b90d6be30ca8716 224 SUPERFAMILY SSF46785 5 70 7.97E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_15805 6236a5c5fd180ae1e6b4f5c891972110 217 PIRSF PIRSF000161 2 197 1.0E-22 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_15805 6236a5c5fd180ae1e6b4f5c891972110 217 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 14 69 4.4E-6 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_15805 6236a5c5fd180ae1e6b4f5c891972110 217 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 80 187 2.2E-7 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TL08_15805 6236a5c5fd180ae1e6b4f5c891972110 217 SUPERFAMILY SSF55347 73 164 7.41E-5 T 12-10-2018 TL08_15805 6236a5c5fd180ae1e6b4f5c891972110 217 Gene3D G3DSA:3.40.50.720 10 191 6.2E-32 T 12-10-2018 TL08_15805 6236a5c5fd180ae1e6b4f5c891972110 217 Gene3D G3DSA:3.30.360.10 73 165 6.2E-32 T 12-10-2018 TL08_15805 6236a5c5fd180ae1e6b4f5c891972110 217 SUPERFAMILY SSF51735 13 71 1.87E-5 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_04605 45e0263d5073875a3abc2653c11dbd28 268 Pfam PF08223 PaaX-like protein C-terminal domain 167 258 6.0E-23 T 12-10-2018 IPR013225 PaaX-like, C-terminal TL08_04605 45e0263d5073875a3abc2653c11dbd28 268 Gene3D G3DSA:3.30.70.2650 90 173 4.2E-5 T 12-10-2018 TL08_04605 45e0263d5073875a3abc2653c11dbd28 268 Gene3D G3DSA:1.10.10.10 7 89 6.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04605 45e0263d5073875a3abc2653c11dbd28 268 PIRSF PIRSF020623 1 268 3.2E-64 T 12-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 TL08_04605 45e0263d5073875a3abc2653c11dbd28 268 Pfam PF07848 PaaX-like protein 8 76 1.4E-15 T 12-10-2018 IPR012906 PaaX-like, N-terminal TL08_10380 d11098a8339cf41fa4e3c61cf5b0d588 188 SUPERFAMILY SSF47413 13 78 2.82E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_10380 d11098a8339cf41fa4e3c61cf5b0d588 188 Gene3D G3DSA:2.60.120.10 100 188 5.9E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_10380 d11098a8339cf41fa4e3c61cf5b0d588 188 Pfam PF01381 Helix-turn-helix 18 70 4.5E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_10380 d11098a8339cf41fa4e3c61cf5b0d588 188 SMART SM00530 17 72 3.8E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_10380 d11098a8339cf41fa4e3c61cf5b0d588 188 Gene3D G3DSA:1.10.260.40 2 83 7.7E-17 T 12-10-2018 TL08_10380 d11098a8339cf41fa4e3c61cf5b0d588 188 SUPERFAMILY SSF51182 65 185 3.28E-19 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_13655 c2df56ac1dfccc99ae8f70c814127a6b 424 Gene3D G3DSA:3.40.190.10 22 413 8.9E-60 T 12-10-2018 TL08_13655 c2df56ac1dfccc99ae8f70c814127a6b 424 SUPERFAMILY SSF53850 21 419 8.28E-56 T 12-10-2018 TL08_13655 c2df56ac1dfccc99ae8f70c814127a6b 424 Pfam PF13416 Bacterial extracellular solute-binding protein 55 356 1.5E-24 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_10635 5b0f636f8b9ebe6280ed64e761f1d7bb 362 PIRSF PIRSF000355 16 362 2.9E-127 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_10635 5b0f636f8b9ebe6280ed64e761f1d7bb 362 SUPERFAMILY SSF47240 26 333 9.2E-96 T 12-10-2018 IPR009078 Ferritin-like superfamily TL08_10635 5b0f636f8b9ebe6280ed64e761f1d7bb 362 Gene3D G3DSA:1.10.620.20 20 355 2.5E-107 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 TL08_10635 5b0f636f8b9ebe6280ed64e761f1d7bb 362 Pfam PF00268 Ribonucleotide reductase, small chain 42 329 1.4E-84 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_11060 f7c82f0982e435a39aed2a24105c22e8 198 SUPERFAMILY SSF55961 3 144 7.74E-28 T 12-10-2018 TL08_11060 f7c82f0982e435a39aed2a24105c22e8 198 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 119 1.3E-17 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 TL08_11060 f7c82f0982e435a39aed2a24105c22e8 198 Gene3D G3DSA:3.30.530.20 1 141 6.1E-36 T 12-10-2018 IPR023393 START-like domain superfamily TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 Gene3D G3DSA:3.40.50.1000 182 373 2.4E-68 T 12-10-2018 IPR023214 HAD superfamily TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 Gene3D G3DSA:3.30.70.260 6 85 2.0E-11 T 12-10-2018 TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 SUPERFAMILY SSF56784 181 390 2.53E-49 T 12-10-2018 IPR036412 HAD-like superfamily TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 Gene3D G3DSA:3.30.70.260 94 179 3.5E-26 T 12-10-2018 TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 169 385 4.4E-71 T 12-10-2018 TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 Pfam PF13740 ACT domain 9 80 2.5E-16 T 12-10-2018 TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 183 353 2.9E-27 T 12-10-2018 TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 SUPERFAMILY SSF55021 7 79 7.2E-9 T 12-10-2018 TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 Pfam PF12710 haloacid dehalogenase-like hydrolase 184 351 1.7E-24 T 12-10-2018 TL08_06430 1a2ffd95501a60b809646ca3bc77fdda 410 Gene3D G3DSA:1.10.150.210 193 253 2.4E-68 T 12-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 TL08_00870 0a339ed9c717ec450f1b28ac357c0d33 165 Pfam PF00583 Acetyltransferase (GNAT) family 35 140 1.1E-11 T 12-10-2018 IPR000182 GNAT domain TL08_00870 0a339ed9c717ec450f1b28ac357c0d33 165 Gene3D G3DSA:3.40.630.30 1 147 1.3E-20 T 12-10-2018 TL08_00870 0a339ed9c717ec450f1b28ac357c0d33 165 SUPERFAMILY SSF55729 1 147 5.32E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_02820 a5eec2248cc59277762723eb4540f0ea 304 Pfam PF07859 alpha/beta hydrolase fold 68 268 1.3E-45 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 TL08_02820 a5eec2248cc59277762723eb4540f0ea 304 Gene3D G3DSA:3.40.50.1820 9 295 7.7E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_02820 a5eec2248cc59277762723eb4540f0ea 304 SUPERFAMILY SSF53474 66 292 7.13E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_09720 2987b06b07b2be2f7f8719afa5ca4ccc 245 PIRSF PIRSF000495 37 245 1.6E-63 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TL08_09720 2987b06b07b2be2f7f8719afa5ca4ccc 245 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 38 243 32.211 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TL08_09720 2987b06b07b2be2f7f8719afa5ca4ccc 245 Gene3D G3DSA:3.40.50.880 35 244 6.1E-68 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_09720 2987b06b07b2be2f7f8719afa5ca4ccc 245 Pfam PF00117 Glutamine amidotransferase class-I 41 236 4.6E-17 T 12-10-2018 IPR017926 Glutamine amidotransferase TL08_09720 2987b06b07b2be2f7f8719afa5ca4ccc 245 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 39 242 4.6E-66 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TL08_09720 2987b06b07b2be2f7f8719afa5ca4ccc 245 SUPERFAMILY SSF52317 39 242 4.45E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_09185 75a57a3fd64a8f7943ebd65c31af31b9 102 Gene3D G3DSA:3.30.70.1120 3 100 1.2E-24 T 12-10-2018 IPR036746 TT1725-like superfamily TL08_09185 75a57a3fd64a8f7943ebd65c31af31b9 102 SUPERFAMILY SSF103007 5 98 1.57E-30 T 12-10-2018 IPR036746 TT1725-like superfamily TL08_09185 75a57a3fd64a8f7943ebd65c31af31b9 102 Pfam PF04456 Protein of unknown function (DUF503) 7 93 4.2E-33 T 12-10-2018 IPR007546 Protein of unknown function DUF503 TL08_20315 6d498c3fd20873a2e33d7413093c9f3d 144 Pfam PF13581 Histidine kinase-like ATPase domain 20 122 6.2E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_20315 6d498c3fd20873a2e33d7413093c9f3d 144 Gene3D G3DSA:3.30.565.10 5 134 7.2E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_20315 6d498c3fd20873a2e33d7413093c9f3d 144 SUPERFAMILY SSF55874 39 115 1.47E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_13480 ca205b14763608ce53f724ed1e38c78c 323 Pfam PF01794 Ferric reductase like transmembrane component 92 216 6.9E-12 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain TL08_25450 8fb2199c69210a0d183df00add1efa4f 364 Pfam PF01180 Dihydroorotate dehydrogenase 50 346 6.1E-94 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TL08_25450 8fb2199c69210a0d183df00add1efa4f 364 Gene3D G3DSA:3.20.20.70 1 364 6.3E-123 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_25450 8fb2199c69210a0d183df00add1efa4f 364 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 343 46.438 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TL08_25450 8fb2199c69210a0d183df00add1efa4f 364 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TL08_25450 8fb2199c69210a0d183df00add1efa4f 364 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 299 319 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TL08_25450 8fb2199c69210a0d183df00add1efa4f 364 SUPERFAMILY SSF51395 1 362 7.94E-98 T 12-10-2018 TL08_25450 8fb2199c69210a0d183df00add1efa4f 364 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 9 363 6.2E-128 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TL08_22350 eb558400005e031c0179b2406c8ac419 870 SMART SM00387 745 857 9.2E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_22350 eb558400005e031c0179b2406c8ac419 870 SUPERFAMILY SSF52402 257 378 2.39E-11 T 12-10-2018 TL08_22350 eb558400005e031c0179b2406c8ac419 870 PRINTS PR00344 Bacterial sensor protein C-terminal signature 784 798 1.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_22350 eb558400005e031c0179b2406c8ac419 870 PRINTS PR00344 Bacterial sensor protein C-terminal signature 817 835 1.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_22350 eb558400005e031c0179b2406c8ac419 870 PRINTS PR00344 Bacterial sensor protein C-terminal signature 841 854 1.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_22350 eb558400005e031c0179b2406c8ac419 870 PRINTS PR00344 Bacterial sensor protein C-terminal signature 802 812 1.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_22350 eb558400005e031c0179b2406c8ac419 870 SUPERFAMILY SSF55874 694 855 4.32E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_22350 eb558400005e031c0179b2406c8ac419 870 SMART SM00388 636 704 2.2E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_22350 eb558400005e031c0179b2406c8ac419 870 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 746 855 3.3E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_22350 eb558400005e031c0179b2406c8ac419 870 Gene3D G3DSA:1.20.120.620 399 503 1.1E-15 T 12-10-2018 IPR038318 KdpD, transmembrane domain superfamily TL08_22350 eb558400005e031c0179b2406c8ac419 870 Pfam PF00512 His Kinase A (phospho-acceptor) domain 637 703 1.8E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_22350 eb558400005e031c0179b2406c8ac419 870 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 27 236 6.4E-96 T 12-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 TL08_22350 eb558400005e031c0179b2406c8ac419 870 SUPERFAMILY SSF47384 625 704 2.75E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_22350 eb558400005e031c0179b2406c8ac419 870 Gene3D G3DSA:3.40.50.620 242 383 2.0E-8 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_22350 eb558400005e031c0179b2406c8ac419 870 Gene3D G3DSA:3.30.565.10 710 862 4.7E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_22350 eb558400005e031c0179b2406c8ac419 870 Pfam PF13493 Domain of unknown function (DUF4118) 403 508 1.9E-23 T 12-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain TL08_22350 eb558400005e031c0179b2406c8ac419 870 Gene3D G3DSA:1.10.287.130 627 702 8.8E-11 T 12-10-2018 TL08_22350 eb558400005e031c0179b2406c8ac419 870 Gene3D G3DSA:3.40.50.300 26 235 1.2E-96 T 12-10-2018 TL08_09875 17548c7c3bacea675184820e79e2b35d 511 Gene3D G3DSA:3.50.50.60 216 342 9.7E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09875 17548c7c3bacea675184820e79e2b35d 511 Gene3D G3DSA:3.50.50.60 23 140 3.4E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_09875 17548c7c3bacea675184820e79e2b35d 511 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 26 507 5.3E-152 T 12-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 TL08_09875 17548c7c3bacea675184820e79e2b35d 511 Pfam PF01593 Flavin containing amine oxidoreductase 33 503 4.9E-46 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TL08_09875 17548c7c3bacea675184820e79e2b35d 511 SUPERFAMILY SSF51905 19 505 4.64E-64 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05185 5699baac6a85acd039a92718f590d207 283 Gene3D G3DSA:3.20.20.30 4 283 8.2E-40 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_05185 5699baac6a85acd039a92718f590d207 283 Pfam PF00296 Luciferase-like monooxygenase 19 231 1.8E-26 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_05185 5699baac6a85acd039a92718f590d207 283 SUPERFAMILY SSF51679 1 282 4.45E-42 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_20330 a6a4932f083ae183939d2548f7881f16 507 Pfam PF00171 Aldehyde dehydrogenase family 22 479 7.8E-103 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_20330 a6a4932f083ae183939d2548f7881f16 507 Gene3D G3DSA:3.40.309.10 253 447 7.6E-108 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_20330 a6a4932f083ae183939d2548f7881f16 507 SUPERFAMILY SSF53720 21 482 1.2E-101 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_20330 a6a4932f083ae183939d2548f7881f16 507 Gene3D G3DSA:3.40.605.10 21 477 7.6E-108 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_01235 378e414d0ce714f3e5c0e854db870258 70 Pfam PF13783 Domain of unknown function (DUF4177) 23 58 9.2E-6 T 12-10-2018 IPR025234 Protein of unknown function DUF4177 TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 SUPERFAMILY SSF46785 16 87 2.1E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 3.1E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 SMART SM00345 25 83 3.3E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 SMART SM00895 93 217 5.2E-17 T 12-10-2018 IPR011711 GntR, C-terminal TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 Gene3D G3DSA:1.10.10.10 15 83 3.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 SUPERFAMILY SSF48008 90 224 1.78E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 Pfam PF07729 FCD domain 93 216 9.0E-22 T 12-10-2018 IPR011711 GntR, C-terminal TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 Gene3D G3DSA:1.20.120.530 87 226 2.3E-29 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 2.5E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_10980 cecbc63acebcdae137496c593d8c10d0 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 2.5E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_13585 cb2ca8b36da03c8b46ef339c7cb86947 502 Gene3D G3DSA:1.20.1250.20 32 458 2.1E-66 T 12-10-2018 TL08_13585 cb2ca8b36da03c8b46ef339c7cb86947 502 SUPERFAMILY SSF103473 43 463 1.31E-77 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_13585 cb2ca8b36da03c8b46ef339c7cb86947 502 Pfam PF07690 Major Facilitator Superfamily 60 421 1.9E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_19825 ed8901621fecdefba5441ea2258e8e23 227 SUPERFAMILY SSF56784 6 214 6.51E-23 T 12-10-2018 IPR036412 HAD-like superfamily TL08_19825 ed8901621fecdefba5441ea2258e8e23 227 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 8 209 1.8E-40 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like TL08_19825 ed8901621fecdefba5441ea2258e8e23 227 Gene3D G3DSA:1.20.1440.100 20 95 5.8E-60 T 12-10-2018 TL08_19825 ed8901621fecdefba5441ea2258e8e23 227 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 8 198 1.5E-19 T 12-10-2018 TL08_19825 ed8901621fecdefba5441ea2258e8e23 227 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 196 5.1E-28 T 12-10-2018 TL08_19825 ed8901621fecdefba5441ea2258e8e23 227 Gene3D G3DSA:3.40.50.1000 9 220 5.8E-60 T 12-10-2018 IPR023214 HAD superfamily TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 SUPERFAMILY SSF46894 4 95 1.96E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 Gene3D G3DSA:1.25.40.10 101 265 1.0E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 SMART SM00862 17 96 5.1E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 Pfam PF00931 NB-ARC domain 316 495 6.5E-15 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 Pfam PF03704 Bacterial transcriptional activator domain 104 248 1.4E-40 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 SUPERFAMILY SSF52540 286 496 1.36E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 77 1.4E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 PRINTS PR00364 Disease resistance protein signature 480 494 8.6E-11 T 12-10-2018 TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 PRINTS PR00364 Disease resistance protein signature 395 409 8.6E-11 T 12-10-2018 TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 PRINTS PR00364 Disease resistance protein signature 319 334 8.6E-11 T 12-10-2018 TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 SMART SM01043 103 248 4.4E-43 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 SUPERFAMILY SSF48452 99 256 4.17E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 Gene3D G3DSA:1.10.10.10 1 98 2.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_10410 a268d4b8a4bcce5a10de6a99f045e1af 671 Gene3D G3DSA:3.40.50.300 281 435 6.7E-26 T 12-10-2018 TL08_05950 365baf15478155f4883dd6c9f613f709 368 Pfam PF06224 Winged helix DNA-binding domain 31 350 7.9E-67 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 TL08_00250 0bc1d503b28cd6e489bb0b9f637718a3 589 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 37 527 4.2E-179 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 TL08_00250 0bc1d503b28cd6e489bb0b9f637718a3 589 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 75 528 1.4E-161 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 TL08_00250 0bc1d503b28cd6e489bb0b9f637718a3 589 ProSitePatterns PS01303 BCCT family of transporters signature. 344 353 - T 12-10-2018 IPR018093 BCCT transporter, conserved site TL08_03270 418b4dc416cb2a5d0e8d256445056093 298 Gene3D G3DSA:3.90.550.10 2 297 1.5E-82 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_03270 418b4dc416cb2a5d0e8d256445056093 298 Pfam PF00483 Nucleotidyl transferase 10 272 2.5E-30 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TL08_03270 418b4dc416cb2a5d0e8d256445056093 298 SUPERFAMILY SSF53448 9 288 8.11E-57 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_01725 eea0fd80b628aaafc56107de6c2ea255 261 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 260 32.808 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TL08_01725 eea0fd80b628aaafc56107de6c2ea255 261 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 256 1.3E-71 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TL08_01725 eea0fd80b628aaafc56107de6c2ea255 261 SUPERFAMILY SSF53067 126 259 3.45E-33 T 12-10-2018 TL08_01725 eea0fd80b628aaafc56107de6c2ea255 261 Gene3D G3DSA:3.30.420.40 1 89 6.5E-20 T 12-10-2018 TL08_01725 eea0fd80b628aaafc56107de6c2ea255 261 Pfam PF03309 Type III pantothenate kinase 2 208 1.0E-59 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TL08_01725 eea0fd80b628aaafc56107de6c2ea255 261 Gene3D G3DSA:3.30.420.40 91 261 4.3E-52 T 12-10-2018 TL08_01725 eea0fd80b628aaafc56107de6c2ea255 261 SUPERFAMILY SSF53067 2 124 2.73E-26 T 12-10-2018 TL08_23150 555654730abadae5d3de23ce7be3f006 309 Gene3D G3DSA:3.40.50.1820 39 289 5.6E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_23150 555654730abadae5d3de23ce7be3f006 309 SUPERFAMILY SSF53474 22 274 1.9E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_23150 555654730abadae5d3de23ce7be3f006 309 Pfam PF07859 alpha/beta hydrolase fold 82 196 2.5E-11 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 TL08_13020 aba2143e9ff5d955e9996fb1a7b0c609 339 SUPERFAMILY SSF53850 37 267 9.47E-35 T 12-10-2018 TL08_13020 aba2143e9ff5d955e9996fb1a7b0c609 339 Gene3D G3DSA:3.40.190.10 119 222 4.0E-66 T 12-10-2018 TL08_13020 aba2143e9ff5d955e9996fb1a7b0c609 339 Gene3D G3DSA:3.40.190.10 40 314 4.0E-66 T 12-10-2018 TL08_13020 aba2143e9ff5d955e9996fb1a7b0c609 339 Pfam PF09084 NMT1/THI5 like 49 256 5.4E-42 T 12-10-2018 IPR015168 SsuA/THI5-like TL08_15605 e8c75602bea7d110180b435a75d1398d 310 Gene3D G3DSA:1.10.287.100 232 271 8.1E-13 T 12-10-2018 TL08_15605 e8c75602bea7d110180b435a75d1398d 310 PIRSF PIRSF028754 6 310 2.9E-92 T 12-10-2018 IPR008492 Protein of unknown function DUF774 TL08_15605 e8c75602bea7d110180b435a75d1398d 310 Pfam PF09754 PAC2 family 27 248 1.5E-45 T 12-10-2018 IPR019151 Proteasome assembly chaperone 2 TL08_15605 e8c75602bea7d110180b435a75d1398d 310 Gene3D G3DSA:3.40.50.10900 2 228 1.1E-71 T 12-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TL08_15605 e8c75602bea7d110180b435a75d1398d 310 SUPERFAMILY SSF159659 6 271 2.22E-84 T 12-10-2018 TL08_17670 521786d95c52cd540578061b4a442997 338 Gene3D G3DSA:1.10.3720.10 86 335 4.0E-69 T 12-10-2018 IPR035906 MetI-like superfamily TL08_17670 521786d95c52cd540578061b4a442997 338 SUPERFAMILY SSF161098 90 323 2.22E-60 T 12-10-2018 IPR035906 MetI-like superfamily TL08_17670 521786d95c52cd540578061b4a442997 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 331 7.1E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_19725 e8b0fa5a6c1412c89a38225fcd34d9a9 362 SMART SM00922 112 212 5.9E-20 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_19725 e8b0fa5a6c1412c89a38225fcd34d9a9 362 Pfam PF13378 Enolase C-terminal domain-like 123 322 1.7E-34 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_19725 e8b0fa5a6c1412c89a38225fcd34d9a9 362 Gene3D G3DSA:3.20.20.120 96 326 7.5E-124 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_19725 e8b0fa5a6c1412c89a38225fcd34d9a9 362 Gene3D G3DSA:3.30.390.10 43 348 7.5E-124 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_19725 e8b0fa5a6c1412c89a38225fcd34d9a9 362 SUPERFAMILY SSF51604 102 322 3.01E-48 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_19725 e8b0fa5a6c1412c89a38225fcd34d9a9 362 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 34 344 22.098 T 12-10-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 TL08_06820 c46dbf4c7256ce7adc9fb0668771603b 271 Pfam PF12840 Helix-turn-helix domain 11 68 2.4E-13 T 12-10-2018 TL08_06820 c46dbf4c7256ce7adc9fb0668771603b 271 Gene3D G3DSA:1.10.10.10 2 110 2.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06820 c46dbf4c7256ce7adc9fb0668771603b 271 SMART SM00418 10 88 9.0E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_06820 c46dbf4c7256ce7adc9fb0668771603b 271 SUPERFAMILY SSF55961 115 267 9.17E-38 T 12-10-2018 TL08_06820 c46dbf4c7256ce7adc9fb0668771603b 271 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 127 265 3.3E-26 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TL08_06820 c46dbf4c7256ce7adc9fb0668771603b 271 Gene3D G3DSA:3.30.530.20 112 270 1.8E-39 T 12-10-2018 IPR023393 START-like domain superfamily TL08_06820 c46dbf4c7256ce7adc9fb0668771603b 271 SUPERFAMILY SSF46785 5 112 1.85E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_03635 68f222400edee9ede8b299671e790a8b 279 Pfam PF03180 NLPA lipoprotein 42 278 6.3E-80 T 12-10-2018 IPR004872 Lipoprotein NlpA family TL08_03635 68f222400edee9ede8b299671e790a8b 279 Gene3D G3DSA:3.40.190.10 42 275 1.6E-88 T 12-10-2018 TL08_03635 68f222400edee9ede8b299671e790a8b 279 SUPERFAMILY SSF53850 42 279 1.54E-71 T 12-10-2018 TL08_03635 68f222400edee9ede8b299671e790a8b 279 PIRSF PIRSF002854 1 279 1.2E-93 T 12-10-2018 IPR004872 Lipoprotein NlpA family TL08_03635 68f222400edee9ede8b299671e790a8b 279 Gene3D G3DSA:3.40.190.10 124 228 1.6E-88 T 12-10-2018 TL08_20360 e5a3edc1b734943264de8ea53eab318c 402 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 33 113 0.007 T 12-10-2018 TL08_20360 e5a3edc1b734943264de8ea53eab318c 402 Pfam PF01594 AI-2E family transporter 33 355 2.0E-58 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like TL08_08715 8f4e738471880efde33e3ea601c988d9 473 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 22 473 3.4E-126 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TL08_08715 8f4e738471880efde33e3ea601c988d9 473 PIRSF PIRSF002746 17 473 1.0E-138 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TL08_08715 8f4e738471880efde33e3ea601c988d9 473 Pfam PF02447 GntP family permease 23 472 1.7E-136 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TL08_03105 b508b3c3a80529160102b57db96dbdba 147 Pfam PF08044 Domain of unknown function (DUF1707) 10 62 4.8E-19 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_11950 d787be9a6d8ed63334be999cb2ba783a 283 Gene3D G3DSA:3.40.630.30 1 136 3.7E-14 T 12-10-2018 TL08_11950 d787be9a6d8ed63334be999cb2ba783a 283 Pfam PF00583 Acetyltransferase (GNAT) family 43 98 5.0E-6 T 12-10-2018 IPR000182 GNAT domain TL08_11950 d787be9a6d8ed63334be999cb2ba783a 283 SUPERFAMILY SSF55729 1 123 1.22E-14 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_27095 760cd62cd69b43c5b72216d117011787 384 Gene3D G3DSA:1.10.101.10 84 157 1.1E-19 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TL08_27095 760cd62cd69b43c5b72216d117011787 384 Gene3D G3DSA:3.40.630.40 178 360 6.7E-41 T 12-10-2018 TL08_27095 760cd62cd69b43c5b72216d117011787 384 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 182 355 8.4E-39 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TL08_27095 760cd62cd69b43c5b72216d117011787 384 Pfam PF01471 Putative peptidoglycan binding domain 94 149 2.3E-18 T 12-10-2018 IPR002477 Peptidoglycan binding-like TL08_27095 760cd62cd69b43c5b72216d117011787 384 Pfam PF01471 Putative peptidoglycan binding domain 10 72 4.7E-10 T 12-10-2018 IPR002477 Peptidoglycan binding-like TL08_27095 760cd62cd69b43c5b72216d117011787 384 SUPERFAMILY SSF47090 88 151 1.49E-19 T 12-10-2018 IPR036365 PGBD-like superfamily TL08_27095 760cd62cd69b43c5b72216d117011787 384 SUPERFAMILY SSF53187 179 358 7.74E-44 T 12-10-2018 TL08_27095 760cd62cd69b43c5b72216d117011787 384 SMART SM00646 240 355 2.1E-31 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TL08_27095 760cd62cd69b43c5b72216d117011787 384 SUPERFAMILY SSF47090 3 73 4.71E-12 T 12-10-2018 IPR036365 PGBD-like superfamily TL08_27095 760cd62cd69b43c5b72216d117011787 384 Gene3D G3DSA:1.10.101.10 1 76 5.9E-12 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TL08_14750 490a208c44e59afa9f96c8b0ce98bacb 333 PIRSF PIRSF029792 1 333 2.9E-121 T 12-10-2018 IPR008794 Proline racemase family TL08_14750 490a208c44e59afa9f96c8b0ce98bacb 333 Gene3D G3DSA:3.10.310.10 146 310 1.4E-119 T 12-10-2018 TL08_14750 490a208c44e59afa9f96c8b0ce98bacb 333 SUPERFAMILY SSF54506 2 331 1.46E-108 T 12-10-2018 TL08_14750 490a208c44e59afa9f96c8b0ce98bacb 333 Gene3D G3DSA:3.10.310.10 7 331 1.4E-119 T 12-10-2018 TL08_14750 490a208c44e59afa9f96c8b0ce98bacb 333 Pfam PF05544 Proline racemase 10 331 1.3E-120 T 12-10-2018 IPR008794 Proline racemase family TL08_26215 05681be727e202e72937a5b16f6d373f 146 Pfam PF04542 Sigma-70 region 2 7 59 5.3E-6 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_26215 05681be727e202e72937a5b16f6d373f 146 SUPERFAMILY SSF88946 2 65 1.57E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_26215 05681be727e202e72937a5b16f6d373f 146 Pfam PF08281 Sigma-70, region 4 86 138 1.9E-19 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_26215 05681be727e202e72937a5b16f6d373f 146 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 1 141 2.6E-47 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 TL08_26215 05681be727e202e72937a5b16f6d373f 146 SUPERFAMILY SSF88659 70 143 3.92E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_26215 05681be727e202e72937a5b16f6d373f 146 Gene3D G3DSA:1.10.10.10 60 145 7.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26215 05681be727e202e72937a5b16f6d373f 146 Gene3D G3DSA:1.10.1740.10 1 59 6.2E-7 T 12-10-2018 TL08_26215 05681be727e202e72937a5b16f6d373f 146 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 140 4.0E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_07630 b449e4695e94ee8a55df0be862da77f6 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 57 9.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_07630 b449e4695e94ee8a55df0be862da77f6 195 SUPERFAMILY SSF46689 4 80 3.44E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_07630 b449e4695e94ee8a55df0be862da77f6 195 Gene3D G3DSA:1.10.357.10 1 194 2.2E-31 T 12-10-2018 TL08_07630 b449e4695e94ee8a55df0be862da77f6 195 SUPERFAMILY SSF48498 80 188 2.82E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_13915 0536aa71d9b70b25a48ddca00aca0d75 115 Pfam PF13397 RNA polymerase-binding protein 4 107 9.0E-43 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 TL08_13915 0536aa71d9b70b25a48ddca00aca0d75 115 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 112 25.207 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 TL08_13915 0536aa71d9b70b25a48ddca00aca0d75 115 Gene3D G3DSA:2.20.28.270 1 80 1.3E-37 T 12-10-2018 IPR038638 RbpA superfamily TL08_16685 4707afef2c197ea81365b751521c2505 136 SUPERFAMILY SSF46785 26 130 5.96E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16685 4707afef2c197ea81365b751521c2505 136 Pfam PF01638 HxlR-like helix-turn-helix 37 121 4.6E-25 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_16685 4707afef2c197ea81365b751521c2505 136 Gene3D G3DSA:1.10.10.10 21 134 1.5E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04610 264046bdff5c2a6efd4b535f57286cda 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 52 2.7E-29 T 12-10-2018 IPR021465 Protein of unknown function DUF3117 TL08_19095 4bd1e5e4fb9c94c021db5d8d6c7b05b8 232 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_19095 4bd1e5e4fb9c94c021db5d8d6c7b05b8 232 SMART SM00382 28 206 3.2E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_19095 4bd1e5e4fb9c94c021db5d8d6c7b05b8 232 Gene3D G3DSA:3.40.50.300 1 228 2.9E-57 T 12-10-2018 TL08_19095 4bd1e5e4fb9c94c021db5d8d6c7b05b8 232 Pfam PF00005 ABC transporter 19 158 1.6E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_19095 4bd1e5e4fb9c94c021db5d8d6c7b05b8 232 SUPERFAMILY SSF52540 4 223 5.11E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25815 2a5ae935457c7005dd3859695bbb7edf 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 3.0E-135 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 Gene3D G3DSA:1.10.630.10 1 404 4.4E-110 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 SUPERFAMILY SSF48264 16 399 5.37E-83 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 PRINTS PR00359 B-class P450 signature 323 338 2.0E-48 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 PRINTS PR00359 B-class P450 signature 94 105 2.0E-48 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 PRINTS PR00359 B-class P450 signature 356 367 2.0E-48 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 PRINTS PR00359 B-class P450 signature 196 218 2.0E-48 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 PRINTS PR00359 B-class P450 signature 277 288 2.0E-48 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 PRINTS PR00359 B-class P450 signature 161 176 2.0E-48 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 PRINTS PR00359 B-class P450 signature 347 356 2.0E-48 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 PRINTS PR00359 B-class P450 signature 295 322 2.0E-48 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 PRINTS PR00359 B-class P450 signature 144 160 2.0E-48 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_19425 da5a42a9204a1a3ab4070d76aafb24bb 404 Pfam PF00067 Cytochrome P450 278 378 7.7E-17 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07510 d1db27882e6f8bfa7a87d0af65adb12e 278 Pfam PF00588 SpoU rRNA Methylase family 124 269 1.9E-32 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TL08_07510 d1db27882e6f8bfa7a87d0af65adb12e 278 Gene3D G3DSA:3.40.1280.10 115 278 1.3E-53 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TL08_07510 d1db27882e6f8bfa7a87d0af65adb12e 278 Gene3D G3DSA:3.30.1330.30 14 114 6.5E-19 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_07510 d1db27882e6f8bfa7a87d0af65adb12e 278 SUPERFAMILY SSF55315 13 96 1.2E-7 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_07510 d1db27882e6f8bfa7a87d0af65adb12e 278 SUPERFAMILY SSF75217 117 276 6.54E-38 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TL08_14155 0986b7c420b0628b3fcf283e27e327a5 496 SUPERFAMILY SSF53474 4 490 2.97E-94 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14155 0986b7c420b0628b3fcf283e27e327a5 496 Pfam PF00135 Carboxylesterase family 4 463 1.5E-77 T 12-10-2018 IPR002018 Carboxylesterase, type B TL08_14155 0986b7c420b0628b3fcf283e27e327a5 496 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 166 181 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site TL08_14155 0986b7c420b0628b3fcf283e27e327a5 496 Gene3D G3DSA:3.40.50.1820 3 488 1.9E-114 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 SUPERFAMILY SSF56024 385 556 1.44E-57 T 12-10-2018 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 SUPERFAMILY SSF56024 562 736 1.17E-57 T 12-10-2018 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 Gene3D G3DSA:3.30.870.10 561 741 5.3E-55 T 12-10-2018 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 PIRSF PIRSF015589 46 742 2.1E-267 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 SUPERFAMILY SSF140356 62 164 2.22E-35 T 12-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 Pfam PF02503 Polyphosphate kinase middle domain 179 379 7.8E-71 T 12-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 Pfam PF13090 Polyphosphate kinase C-terminal domain 390 734 1.4E-145 T 12-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 Pfam PF13089 Polyphosphate kinase N-terminal domain 65 170 3.0E-35 T 12-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 SUPERFAMILY SSF143724 169 369 2.94E-66 T 12-10-2018 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 Gene3D G3DSA:3.30.1840.10 58 370 1.2E-116 T 12-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 64 734 1.3E-247 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 Hamap MF_00347 Polyphosphate kinase [ppk]. 62 740 28.258 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 TL08_22630 95ecc94afc2634f6d094eb55ea4e47a8 742 Gene3D G3DSA:3.30.870.10 378 560 1.2E-74 T 12-10-2018 TL08_11200 658e4f0dd9bdec87f8d83fdc6b7b34e9 196 Pfam PF00857 Isochorismatase family 4 164 1.0E-29 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 TL08_11200 658e4f0dd9bdec87f8d83fdc6b7b34e9 196 Gene3D G3DSA:3.40.50.850 1 194 3.1E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TL08_11200 658e4f0dd9bdec87f8d83fdc6b7b34e9 196 SUPERFAMILY SSF52499 3 193 9.94E-37 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TL08_24955 18165fd112996a3624c9a73403d407ef 468 Gene3D G3DSA:3.10.20.90 4 85 4.0E-13 T 12-10-2018 TL08_24955 18165fd112996a3624c9a73403d407ef 468 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 459 2.4E-83 T 12-10-2018 IPR006707 Type VII secretion system membrane protein EccD TL08_24955 18165fd112996a3624c9a73403d407ef 468 PIRSF PIRSF017804 1 462 9.3E-116 T 12-10-2018 IPR006707 Type VII secretion system membrane protein EccD TL08_24955 18165fd112996a3624c9a73403d407ef 468 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 84 4.8E-21 T 12-10-2018 IPR024962 YukD-like TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 86 354 7.5E-38 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 628 865 2.5E-59 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 Pfam PF08335 GlnD PII-uridylyltransferase 887 1030 3.1E-21 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 Pfam PF08335 GlnD PII-uridylyltransferase 377 523 8.0E-33 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 Gene3D G3DSA:3.30.460.100 95 360 5.1E-54 T 12-10-2018 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 Gene3D G3DSA:3.30.460.100 637 871 5.3E-59 T 12-10-2018 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 SUPERFAMILY SSF81593 369 524 5.73E-36 T 12-10-2018 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 SUPERFAMILY SSF81301 600 874 5.89E-64 T 12-10-2018 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 SUPERFAMILY SSF81593 881 1032 3.69E-34 T 12-10-2018 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 Gene3D G3DSA:1.20.120.330 880 1034 6.2E-35 T 12-10-2018 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 Gene3D G3DSA:1.20.120.330 369 525 1.3E-39 T 12-10-2018 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 SUPERFAMILY SSF81301 70 363 3.24E-55 T 12-10-2018 TL08_21945 b774a7fd414d787bdaaa01d899ae9640 1034 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 83 1022 16.318 T 12-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 TL08_05745 684a560f9ea84cf6bdad4a8c806a3ffb 312 SMART SM00382 29 239 9.6E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_05745 684a560f9ea84cf6bdad4a8c806a3ffb 312 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_05745 684a560f9ea84cf6bdad4a8c806a3ffb 312 SUPERFAMILY SSF52540 4 227 1.38E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05745 684a560f9ea84cf6bdad4a8c806a3ffb 312 Pfam PF00005 ABC transporter 20 163 4.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05745 684a560f9ea84cf6bdad4a8c806a3ffb 312 Gene3D G3DSA:3.40.50.300 2 237 5.1E-72 T 12-10-2018 TL08_00485 bc7b692c2dc6b459b4484c6bab65ca8f 641 Gene3D G3DSA:3.40.50.300 449 639 4.4E-15 T 12-10-2018 TL08_00485 bc7b692c2dc6b459b4484c6bab65ca8f 641 SUPERFAMILY SSF52540 171 628 2.04E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_00485 bc7b692c2dc6b459b4484c6bab65ca8f 641 Pfam PF13245 AAA domain 179 428 8.7E-15 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 Gene3D G3DSA:3.50.30.20 5 153 9.3E-55 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 5 373 44.586 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 Gene3D G3DSA:3.40.50.880 156 372 8.2E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_11495 eef5a047a704be32881d960a43f82ba0 377 SMART SM01097 5 135 6.0E-80 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 7 370 1.9E-133 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 SUPERFAMILY SSF52317 156 371 5.2E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 270 287 5.2E-32 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 253 269 5.2E-32 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 183 197 5.2E-32 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 222 236 5.2E-32 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 295 306 5.2E-32 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 Pfam PF00117 Glutamine amidotransferase class-I 187 367 6.4E-36 T 12-10-2018 IPR017926 Glutamine amidotransferase TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 225 234 3.9E-11 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 344 357 3.9E-11 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 253 264 3.9E-11 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 SUPERFAMILY SSF52021 6 138 8.11E-53 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 7 133 3.0E-50 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00097 Anthranilate synthase component II signature 225 234 8.4E-6 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00097 Anthranilate synthase component II signature 253 264 8.4E-6 T 12-10-2018 TL08_11495 eef5a047a704be32881d960a43f82ba0 377 PRINTS PR00097 Anthranilate synthase component II signature 344 357 8.4E-6 T 12-10-2018 TL08_10630 30cda5265765cdf56bb9ab5282e6671e 186 SUPERFAMILY SSF52540 13 180 1.15E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10630 30cda5265765cdf56bb9ab5282e6671e 186 Pfam PF13238 AAA domain 19 140 1.7E-8 T 12-10-2018 TL08_10630 30cda5265765cdf56bb9ab5282e6671e 186 Gene3D G3DSA:3.40.50.300 9 184 2.0E-35 T 12-10-2018 TL08_18380 c14b6e95af1dd1f33d6ffe5746529d3c 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18380 c14b6e95af1dd1f33d6ffe5746529d3c 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 7.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18380 c14b6e95af1dd1f33d6ffe5746529d3c 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 7.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18380 c14b6e95af1dd1f33d6ffe5746529d3c 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 7.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18380 c14b6e95af1dd1f33d6ffe5746529d3c 291 Pfam PF00106 short chain dehydrogenase 7 214 1.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_18380 c14b6e95af1dd1f33d6ffe5746529d3c 291 Gene3D G3DSA:3.40.50.720 2 258 3.7E-43 T 12-10-2018 TL08_18380 c14b6e95af1dd1f33d6ffe5746529d3c 291 SUPERFAMILY SSF51735 2 248 4.69E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_18115 b39006fcd27db7e8cbd77aa88bba997e 305 SUPERFAMILY SSF53633 15 301 2.62E-86 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TL08_18115 b39006fcd27db7e8cbd77aa88bba997e 305 Hamap MF_00082 Acetylglutamate kinase [argB]. 35 293 46.157 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_18115 b39006fcd27db7e8cbd77aa88bba997e 305 PRINTS PR00474 Glutamate 5-kinase family signature 199 226 2.6E-9 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TL08_18115 b39006fcd27db7e8cbd77aa88bba997e 305 PRINTS PR00474 Glutamate 5-kinase family signature 67 81 2.6E-9 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TL08_18115 b39006fcd27db7e8cbd77aa88bba997e 305 PRINTS PR00474 Glutamate 5-kinase family signature 250 270 2.6E-9 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TL08_18115 b39006fcd27db7e8cbd77aa88bba997e 305 TIGRFAM TIGR00761 argB: acetylglutamate kinase 37 275 2.8E-77 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_18115 b39006fcd27db7e8cbd77aa88bba997e 305 PIRSF PIRSF000728 21 299 2.0E-99 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_18115 b39006fcd27db7e8cbd77aa88bba997e 305 Pfam PF00696 Amino acid kinase family 37 277 4.0E-43 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TL08_18115 b39006fcd27db7e8cbd77aa88bba997e 305 Gene3D G3DSA:3.40.1160.10 13 304 1.7E-101 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TL08_26010 8e84f176ba600474107abb29d2f0a9c6 364 SUPERFAMILY SSF55326 11 173 1.45E-44 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TL08_26010 8e84f176ba600474107abb29d2f0a9c6 364 Gene3D G3DSA:3.90.650.10 176 352 3.7E-59 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TL08_26010 8e84f176ba600474107abb29d2f0a9c6 364 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 11 340 3.3E-135 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26010 8e84f176ba600474107abb29d2f0a9c6 364 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 10 355 41.841 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26010 8e84f176ba600474107abb29d2f0a9c6 364 Pfam PF02769 AIR synthase related protein, C-terminal domain 180 346 7.5E-34 T 12-10-2018 IPR010918 PurM-like, C-terminal domain TL08_26010 8e84f176ba600474107abb29d2f0a9c6 364 Pfam PF00586 AIR synthase related protein, N-terminal domain 65 168 1.0E-15 T 12-10-2018 IPR016188 PurM-like, N-terminal domain TL08_26010 8e84f176ba600474107abb29d2f0a9c6 364 SUPERFAMILY SSF56042 176 345 5.08E-54 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TL08_26010 8e84f176ba600474107abb29d2f0a9c6 364 Gene3D G3DSA:3.30.1330.10 9 174 2.0E-59 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TL08_07685 d26add99a0b2617f0855db6d9b1ccdf6 196 SMART SM00903 45 192 5.5E-40 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TL08_07685 d26add99a0b2617f0855db6d9b1ccdf6 196 SUPERFAMILY SSF50475 40 192 1.32E-39 T 12-10-2018 TL08_07685 d26add99a0b2617f0855db6d9b1ccdf6 196 Pfam PF01613 Flavin reductase like domain 45 193 6.6E-30 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TL08_07685 d26add99a0b2617f0855db6d9b1ccdf6 196 Gene3D G3DSA:2.30.110.10 34 195 4.2E-43 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_11130 0f1a10064f662c909a70711cd6339fae 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 17 133 2.0E-27 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_11130 0f1a10064f662c909a70711cd6339fae 337 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 207 6.7E-6 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TL08_11130 0f1a10064f662c909a70711cd6339fae 337 SUPERFAMILY SSF51735 14 168 3.84E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_11130 0f1a10064f662c909a70711cd6339fae 337 Gene3D G3DSA:3.30.360.10 135 335 5.5E-53 T 12-10-2018 TL08_11130 0f1a10064f662c909a70711cd6339fae 337 SUPERFAMILY SSF55347 141 304 1.8E-38 T 12-10-2018 TL08_11130 0f1a10064f662c909a70711cd6339fae 337 Gene3D G3DSA:3.40.50.720 14 134 9.3E-42 T 12-10-2018 TL08_17020 bce957091ee70095dd4f530bb2d10eec 282 Pfam PF17197 Domain of unknown function (DUF5134) 40 281 2.1E-33 T 12-10-2018 IPR033458 Protein of unknown function DUF5134 TL08_17020 bce957091ee70095dd4f530bb2d10eec 282 ProDom PD338207 MEMBRANE INTEGRAL TRANSMEMBRANE PLASMID PROBABLE MB0995 RV0970/MT0998 1 72 7.0E-5 T 12-10-2018 TL08_19375 0b025fb40aa0307d1f7e1a186f7a5db1 303 Gene3D G3DSA:1.10.3720.10 58 297 1.2E-71 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19375 0b025fb40aa0307d1f7e1a186f7a5db1 303 SUPERFAMILY SSF161098 62 290 3.79E-63 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19375 0b025fb40aa0307d1f7e1a186f7a5db1 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 290 8.7E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_13415 e9613b493db3765f4ecde942f96b74a9 377 Gene3D G3DSA:3.40.47.10 234 377 1.0E-38 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_13415 e9613b493db3765f4ecde942f96b74a9 377 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 243 376 1.2E-15 T 12-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal TL08_13415 e9613b493db3765f4ecde942f96b74a9 377 Gene3D G3DSA:3.40.47.10 27 231 3.6E-63 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_13415 e9613b493db3765f4ecde942f96b74a9 377 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 27 224 1.2E-20 T 12-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal TL08_13415 e9613b493db3765f4ecde942f96b74a9 377 SUPERFAMILY SSF53901 26 227 4.56E-47 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_13415 e9613b493db3765f4ecde942f96b74a9 377 SUPERFAMILY SSF53901 234 377 7.49E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_13415 e9613b493db3765f4ecde942f96b74a9 377 PIRSF PIRSF000451 13 377 1.8E-116 T 12-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 TL08_12150 06617a999332e52a9c218fbaefdd7f00 282 SUPERFAMILY SSF53335 12 211 9.76E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_12150 06617a999332e52a9c218fbaefdd7f00 282 PIRSF PIRSF018249 1 280 6.7E-81 T 12-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 TL08_12150 06617a999332e52a9c218fbaefdd7f00 282 Gene3D G3DSA:3.40.50.150 9 278 1.3E-65 T 12-10-2018 TL08_12150 06617a999332e52a9c218fbaefdd7f00 282 Pfam PF13649 Methyltransferase domain 94 176 1.5E-6 T 12-10-2018 TL08_07950 0b7ff216367246ef6820ada455623d4b 157 SUPERFAMILY SSF89623 2 150 1.83E-49 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TL08_07950 0b7ff216367246ef6820ada455623d4b 157 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 9.3E-65 T 12-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 TL08_07950 0b7ff216367246ef6820ada455623d4b 157 Pfam PF02502 Ribose/Galactose Isomerase 3 140 2.3E-42 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TL08_07950 0b7ff216367246ef6820ada455623d4b 157 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 4.2E-51 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TL08_07950 0b7ff216367246ef6820ada455623d4b 157 PIRSF PIRSF005384 1 149 5.5E-46 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TL08_07950 0b7ff216367246ef6820ada455623d4b 157 Gene3D G3DSA:3.40.1400.10 1 156 1.0E-53 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TL08_09445 6b754509d3c65fbdcca8ea54b56d1cbc 328 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 16 323 36.515 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TL08_09445 6b754509d3c65fbdcca8ea54b56d1cbc 328 PIRSF PIRSF004486 10 324 6.5E-93 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TL08_09445 6b754509d3c65fbdcca8ea54b56d1cbc 328 SUPERFAMILY SSF81799 127 228 1.7E-32 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TL08_09445 6b754509d3c65fbdcca8ea54b56d1cbc 328 Pfam PF01795 MraW methylase family 14 322 5.6E-105 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TL08_09445 6b754509d3c65fbdcca8ea54b56d1cbc 328 Gene3D G3DSA:3.40.50.150 16 319 4.2E-92 T 12-10-2018 TL08_09445 6b754509d3c65fbdcca8ea54b56d1cbc 328 Gene3D G3DSA:1.10.150.170 125 230 4.2E-92 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TL08_09445 6b754509d3c65fbdcca8ea54b56d1cbc 328 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 14 322 1.5E-87 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TL08_09445 6b754509d3c65fbdcca8ea54b56d1cbc 328 SUPERFAMILY SSF53335 16 323 1.54E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_09330 222652a9439b06943d5b03284b1dbb7a 185 SUPERFAMILY SSF47598 104 157 6.23E-10 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TL08_09330 222652a9439b06943d5b03284b1dbb7a 185 Pfam PF05534 HicB family 109 139 8.3E-7 T 12-10-2018 IPR008651 Uncharacterised protein family HicB TL08_09565 1e4e16372431b2d0f3e278f035c7ebeb 294 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 93 250 14.991 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09565 1e4e16372431b2d0f3e278f035c7ebeb 294 Pfam PF01252 Signal peptidase (SPase) II 102 243 7.9E-29 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09565 1e4e16372431b2d0f3e278f035c7ebeb 294 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 225 241 2.3E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09565 1e4e16372431b2d0f3e278f035c7ebeb 294 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 140 148 2.3E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09565 1e4e16372431b2d0f3e278f035c7ebeb 294 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 182 197 2.3E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09565 1e4e16372431b2d0f3e278f035c7ebeb 294 TIGRFAM TIGR00077 lspA: signal peptidase II 97 246 8.9E-28 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09565 1e4e16372431b2d0f3e278f035c7ebeb 294 ProSitePatterns PS00855 Signal peptidases II signature. 185 197 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_17390 5c6075a2fc600478236f78e2513db679 350 Gene3D G3DSA:3.90.180.10 15 346 1.4E-97 T 12-10-2018 TL08_17390 5c6075a2fc600478236f78e2513db679 350 SUPERFAMILY SSF51735 147 283 7.76E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_17390 5c6075a2fc600478236f78e2513db679 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 1.5E-13 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_17390 5c6075a2fc600478236f78e2513db679 350 Pfam PF16912 Glucose dehydrogenase C-terminus 145 348 1.1E-63 T 12-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 TL08_17390 5c6075a2fc600478236f78e2513db679 350 Gene3D G3DSA:3.40.50.720 147 322 1.4E-97 T 12-10-2018 TL08_17390 5c6075a2fc600478236f78e2513db679 350 SUPERFAMILY SSF50129 1 183 5.78E-33 T 12-10-2018 IPR011032 GroES-like superfamily TL08_24925 0be65cd3b26b366aa910b64474cef4c8 147 Pfam PF00572 Ribosomal protein L13 15 138 4.0E-55 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TL08_24925 0be65cd3b26b366aa910b64474cef4c8 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 143 28.93 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TL08_24925 0be65cd3b26b366aa910b64474cef4c8 147 PIRSF PIRSF002181 2 147 1.9E-50 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TL08_24925 0be65cd3b26b366aa910b64474cef4c8 147 SUPERFAMILY SSF52161 4 142 1.96E-59 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TL08_24925 0be65cd3b26b366aa910b64474cef4c8 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 12-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TL08_24925 0be65cd3b26b366aa910b64474cef4c8 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 4.3E-60 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_24925 0be65cd3b26b366aa910b64474cef4c8 147 Gene3D G3DSA:3.90.1180.10 1 142 4.5E-61 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TL08_18005 af411389712e719e086bd54de3e94cbc 388 Pfam PF01757 Acyltransferase family 11 355 8.6E-13 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_12700 1c88121a5b57037b72e6f5eb46642b35 192 Pfam PF03079 ARD/ARD' family 17 169 1.8E-28 T 12-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 TL08_12700 1c88121a5b57037b72e6f5eb46642b35 192 Gene3D G3DSA:2.60.120.10 2 162 2.6E-44 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_12700 1c88121a5b57037b72e6f5eb46642b35 192 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 177 34.265 T 12-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 TL08_12700 1c88121a5b57037b72e6f5eb46642b35 192 SUPERFAMILY SSF51182 5 183 3.63E-29 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_21660 194e367d105376f9c5fa64fade03f09a 174 Pfam PF16473 3' exoribonuclease, RNase T-like 2 155 1.3E-17 T 12-10-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain TL08_21660 194e367d105376f9c5fa64fade03f09a 174 SUPERFAMILY SSF53098 4 154 9.2E-7 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_21660 194e367d105376f9c5fa64fade03f09a 174 Hamap MF_00977 3'-5' exoribonuclease. 1 159 43.089 T 12-10-2018 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 TL08_21660 194e367d105376f9c5fa64fade03f09a 174 Gene3D G3DSA:3.30.420.10 1 164 4.0E-63 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_05840 1f718285a19a916a377dc7ec2ae1b011 228 Gene3D G3DSA:3.40.50.150 1 216 1.0E-60 T 12-10-2018 TL08_05840 1f718285a19a916a377dc7ec2ae1b011 228 Pfam PF02390 Putative methyltransferase 26 83 1.3E-5 T 12-10-2018 TL08_05840 1f718285a19a916a377dc7ec2ae1b011 228 SUPERFAMILY SSF53335 23 183 2.59E-12 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13975 2d5359d3a9b1a6c19962976b421e5472 185 Gene3D G3DSA:3.40.630.30 3 184 1.0E-43 T 12-10-2018 TL08_13975 2d5359d3a9b1a6c19962976b421e5472 185 Pfam PF13302 Acetyltransferase (GNAT) domain 16 157 1.5E-29 T 12-10-2018 IPR000182 GNAT domain TL08_13975 2d5359d3a9b1a6c19962976b421e5472 185 SUPERFAMILY SSF55729 10 180 2.39E-40 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_07845 2c8ce4d6a81fa732999417ac43670226 152 Pfam PF03061 Thioesterase superfamily 18 97 3.1E-10 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TL08_07845 2c8ce4d6a81fa732999417ac43670226 152 SUPERFAMILY SSF54637 4 136 5.86E-27 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_07845 2c8ce4d6a81fa732999417ac43670226 152 Gene3D G3DSA:3.10.129.10 2 140 1.3E-30 T 12-10-2018 TL08_09375 48001f0d2fb636eb13c99af7db35b79e 206 Pfam PF01066 CDP-alcohol phosphatidyltransferase 22 92 7.9E-14 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TL08_09375 48001f0d2fb636eb13c99af7db35b79e 206 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 70 92 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TL08_09375 48001f0d2fb636eb13c99af7db35b79e 206 Gene3D G3DSA:1.20.120.1760 21 197 1.2E-9 T 12-10-2018 TL08_09375 48001f0d2fb636eb13c99af7db35b79e 206 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 21 193 2.6E-41 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 TL08_09375 48001f0d2fb636eb13c99af7db35b79e 206 PIRSF PIRSF000847 19 202 5.3E-45 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 TL08_26840 05c3a4aba98b216c57114e5e4ed73917 98 Pfam PF01250 Ribosomal protein S6 3 92 1.8E-26 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26840 05c3a4aba98b216c57114e5e4ed73917 98 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 4.2E-25 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26840 05c3a4aba98b216c57114e5e4ed73917 98 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.803 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 TL08_26840 05c3a4aba98b216c57114e5e4ed73917 98 SUPERFAMILY SSF54995 1 95 2.75E-31 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26840 05c3a4aba98b216c57114e5e4ed73917 98 Gene3D G3DSA:3.30.70.60 1 98 1.1E-30 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TL08_18510 3d98f1dd3ece7837749aa1deb5acdbf2 69 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 60 1.4E-12 T 12-10-2018 TL08_18510 3d98f1dd3ece7837749aa1deb5acdbf2 69 Gene3D G3DSA:3.30.70.20 1 62 2.2E-18 T 12-10-2018 TL08_18510 3d98f1dd3ece7837749aa1deb5acdbf2 69 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 5.8E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_18510 3d98f1dd3ece7837749aa1deb5acdbf2 69 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 5.8E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_18510 3d98f1dd3ece7837749aa1deb5acdbf2 69 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 5.8E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_18510 3d98f1dd3ece7837749aa1deb5acdbf2 69 SUPERFAMILY SSF54862 2 61 6.7E-12 T 12-10-2018 TL08_20690 1dcd96f9cac5ef463e53e3fd252ce3dc 444 Gene3D G3DSA:2.160.20.10 40 444 2.5E-151 T 12-10-2018 IPR012334 Pectin lyase fold TL08_20690 1dcd96f9cac5ef463e53e3fd252ce3dc 444 SUPERFAMILY SSF51126 43 443 7.21E-75 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_20690 1dcd96f9cac5ef463e53e3fd252ce3dc 444 SMART SM00656 118 367 1.8E-47 T 12-10-2018 IPR002022 Pectate lyase TL08_20690 1dcd96f9cac5ef463e53e3fd252ce3dc 444 Pfam PF00544 Pectate lyase 147 361 5.2E-51 T 12-10-2018 IPR002022 Pectate lyase TL08_05355 d3a767fea013878fcb300ba57957c648 178 Gene3D G3DSA:2.30.110.10 37 170 2.6E-16 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_05355 d3a767fea013878fcb300ba57957c648 178 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 42 118 5.8E-7 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_05355 d3a767fea013878fcb300ba57957c648 178 SUPERFAMILY SSF50475 41 160 2.81E-14 T 12-10-2018 TL08_04250 48a46a72cd327e40efce65a32e67a1fe 214 Pfam PF01872 RibD C-terminal domain 8 185 2.0E-10 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TL08_04250 48a46a72cd327e40efce65a32e67a1fe 214 Gene3D G3DSA:3.40.430.10 3 210 3.8E-33 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_04250 48a46a72cd327e40efce65a32e67a1fe 214 SUPERFAMILY SSF53597 56 207 1.45E-18 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_24575 ecb76c7aa6048d7033dd37ff4ffb5870 220 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 23 209 9.0E-65 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TL08_24575 ecb76c7aa6048d7033dd37ff4ffb5870 220 SUPERFAMILY SSF53328 23 218 1.01E-57 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TL08_24575 ecb76c7aa6048d7033dd37ff4ffb5870 220 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 23 208 28.598 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TL08_24575 ecb76c7aa6048d7033dd37ff4ffb5870 220 Pfam PF00551 Formyl transferase 23 202 2.1E-49 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TL08_24575 ecb76c7aa6048d7033dd37ff4ffb5870 220 Gene3D G3DSA:3.40.50.170 14 220 8.4E-76 T 12-10-2018 TL08_08610 e4ef82d9b2d5fd294ae13a383ddb8481 133 SUPERFAMILY SSF55021 1 56 4.44E-8 T 12-10-2018 TL08_08610 e4ef82d9b2d5fd294ae13a383ddb8481 133 Pfam PF13840 ACT domain 66 125 1.3E-14 T 12-10-2018 IPR027795 CASTOR, ACT domain TL08_08610 e4ef82d9b2d5fd294ae13a383ddb8481 133 Gene3D G3DSA:3.30.2130.10 1 133 5.4E-38 T 12-10-2018 TL08_08610 e4ef82d9b2d5fd294ae13a383ddb8481 133 PIRSF PIRSF008459 1 133 3.1E-22 T 12-10-2018 IPR016540 Uncharacterised conserved protein UCP008459 TL08_08610 e4ef82d9b2d5fd294ae13a383ddb8481 133 SUPERFAMILY SSF55021 66 130 3.36E-14 T 12-10-2018 TL08_09685 1f0f76e5947811141d3c4ad9b406bcb4 377 Pfam PF00155 Aminotransferase class I and II 39 365 6.5E-55 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_09685 1f0f76e5947811141d3c4ad9b406bcb4 377 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 234 243 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TL08_09685 1f0f76e5947811141d3c4ad9b406bcb4 377 Gene3D G3DSA:3.90.1150.10 24 366 1.4E-126 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_09685 1f0f76e5947811141d3c4ad9b406bcb4 377 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 19 371 54.114 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TL08_09685 1f0f76e5947811141d3c4ad9b406bcb4 377 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 21 370 6.9E-98 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TL08_09685 1f0f76e5947811141d3c4ad9b406bcb4 377 Gene3D G3DSA:3.40.640.10 61 284 1.4E-126 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_09685 1f0f76e5947811141d3c4ad9b406bcb4 377 SUPERFAMILY SSF53383 38 366 2.2E-70 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_09950 fe604033fca911db8c9d5efb59804c17 329 SUPERFAMILY SSF48317 52 202 2.75E-30 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TL08_09950 fe604033fca911db8c9d5efb59804c17 329 SMART SM00014 88 198 7.8E-13 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TL08_09950 fe604033fca911db8c9d5efb59804c17 329 Pfam PF01569 PAP2 superfamily 92 199 6.5E-23 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TL08_09950 fe604033fca911db8c9d5efb59804c17 329 Gene3D G3DSA:1.20.144.10 73 202 9.7E-19 T 12-10-2018 TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 Gene3D G3DSA:3.30.360.10 138 343 3.0E-125 T 12-10-2018 TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 SMART SM00859 14 130 4.9E-35 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 SUPERFAMILY SSF51735 14 166 1.08E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 149 346 2.8E-45 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 15 360 9.6E-116 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 PIRSF PIRSF000148 12 363 2.0E-108 T 12-10-2018 TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 SUPERFAMILY SSF55347 139 347 3.41E-65 T 12-10-2018 TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 12 360 32.142 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 15 128 8.5E-27 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TL08_01140 6567ce909bba3748623e6f26c4d0da35 363 Gene3D G3DSA:3.40.50.720 16 357 3.0E-125 T 12-10-2018 TL08_06475 777a1206f9ef61178cd895f2e3208b62 99 SUPERFAMILY SSF54736 22 97 5.75E-25 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TL08_06475 777a1206f9ef61178cd895f2e3208b62 99 Gene3D G3DSA:3.30.1390.10 3 96 1.9E-18 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TL08_06475 777a1206f9ef61178cd895f2e3208b62 99 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 22 93 1.8E-22 T 12-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 TL08_06475 777a1206f9ef61178cd895f2e3208b62 99 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 2 99 18.042 T 12-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS TL08_08235 a58e70a40f37bd595b93b43bb7e5bf9c 203 SMART SM00855 5 157 2.0E-21 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_08235 a58e70a40f37bd595b93b43bb7e5bf9c 203 SUPERFAMILY SSF53254 5 198 4.57E-53 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_08235 a58e70a40f37bd595b93b43bb7e5bf9c 203 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 TL08_08235 a58e70a40f37bd595b93b43bb7e5bf9c 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 196 8.1E-54 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_08235 a58e70a40f37bd595b93b43bb7e5bf9c 203 Gene3D G3DSA:3.40.50.1240 2 202 2.6E-63 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_08235 a58e70a40f37bd595b93b43bb7e5bf9c 203 PIRSF PIRSF000709 3 169 1.5E-12 T 12-10-2018 TL08_10495 41404fc7024dbd8e9a05d5ae8c161295 100 SUPERFAMILY SSF54909 14 98 1.49E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_10495 41404fc7024dbd8e9a05d5ae8c161295 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 16 74 1.1E-8 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TL08_10495 41404fc7024dbd8e9a05d5ae8c161295 100 Gene3D G3DSA:3.30.70.100 5 96 1.5E-13 T 12-10-2018 TL08_20040 5d9cbd1d0e51d9aff546bdb155f2d4d1 62 Pfam PF04149 Domain of unknown function (DUF397) 8 60 1.3E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_14040 24170b74ed88de5bf321386ba59f4d52 307 PIRSF PIRSF000103 15 307 1.7E-38 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TL08_14040 24170b74ed88de5bf321386ba59f4d52 307 Gene3D G3DSA:3.40.50.720 16 175 1.2E-36 T 12-10-2018 TL08_14040 24170b74ed88de5bf321386ba59f4d52 307 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 22 170 1.1E-20 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TL08_14040 24170b74ed88de5bf321386ba59f4d52 307 SUPERFAMILY SSF51735 22 170 1.6E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14040 24170b74ed88de5bf321386ba59f4d52 307 Gene3D G3DSA:1.10.1040.10 177 306 1.8E-40 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TL08_04960 241b9d81bfcf045ec1cdd4963532f2b7 229 SUPERFAMILY SSF52540 1 221 1.4E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04960 241b9d81bfcf045ec1cdd4963532f2b7 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_04960 241b9d81bfcf045ec1cdd4963532f2b7 229 Gene3D G3DSA:3.40.50.300 1 225 1.2E-68 T 12-10-2018 TL08_04960 241b9d81bfcf045ec1cdd4963532f2b7 229 SMART SM00382 28 215 4.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_04960 241b9d81bfcf045ec1cdd4963532f2b7 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 7.7E-86 T 12-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 TL08_04960 241b9d81bfcf045ec1cdd4963532f2b7 229 Pfam PF00005 ABC transporter 19 166 3.3E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12930 123c683c8f3b31616462da4583a3cbe1 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TL08_12930 123c683c8f3b31616462da4583a3cbe1 479 Gene3D G3DSA:3.40.605.10 28 463 2.4E-142 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_12930 123c683c8f3b31616462da4583a3cbe1 479 Gene3D G3DSA:3.40.309.10 251 443 2.4E-142 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_12930 123c683c8f3b31616462da4583a3cbe1 479 SUPERFAMILY SSF53720 4 474 7.2E-135 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_12930 123c683c8f3b31616462da4583a3cbe1 479 Pfam PF00171 Aldehyde dehydrogenase family 18 470 3.0E-131 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_21200 b5e4cd8a7aea0ae32b9eecd0257a6883 382 SUPERFAMILY SSF53474 5 380 1.82E-92 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21200 b5e4cd8a7aea0ae32b9eecd0257a6883 382 Gene3D G3DSA:3.40.50.1820 8 382 2.5E-134 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21200 b5e4cd8a7aea0ae32b9eecd0257a6883 382 PIRSF PIRSF001112 2 382 1.4E-117 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 TL08_21200 b5e4cd8a7aea0ae32b9eecd0257a6883 382 Pfam PF06441 Epoxide hydrolase N terminus 8 113 5.3E-38 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 TL08_21200 b5e4cd8a7aea0ae32b9eecd0257a6883 382 PRINTS PR00412 Epoxide hydrolase signature 104 122 5.2E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_21200 b5e4cd8a7aea0ae32b9eecd0257a6883 382 PRINTS PR00412 Epoxide hydrolase signature 133 148 5.2E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_21200 b5e4cd8a7aea0ae32b9eecd0257a6883 382 PRINTS PR00412 Epoxide hydrolase signature 355 377 5.2E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_21200 b5e4cd8a7aea0ae32b9eecd0257a6883 382 PRINTS PR00412 Epoxide hydrolase signature 179 192 5.2E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05645 d89f43ea229c73a8cad6db13ad79db71 397 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 395 1.3E-124 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 TL08_05645 d89f43ea229c73a8cad6db13ad79db71 397 Gene3D G3DSA:3.40.50.2000 216 378 4.1E-131 T 12-10-2018 TL08_05645 d89f43ea229c73a8cad6db13ad79db71 397 SUPERFAMILY SSF53756 1 393 1.18E-72 T 12-10-2018 TL08_05645 d89f43ea229c73a8cad6db13ad79db71 397 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 278 375 1.9E-11 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TL08_05645 d89f43ea229c73a8cad6db13ad79db71 397 Gene3D G3DSA:3.40.50.2000 6 390 4.1E-131 T 12-10-2018 TL08_24245 341f044ba4267e68cbefd7b84a6cf4ca 195 Pfam PF16859 Bacterial transcriptional repressor C-terminal 70 178 3.3E-26 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TL08_24245 341f044ba4267e68cbefd7b84a6cf4ca 195 SUPERFAMILY SSF48498 70 187 3.05E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_24245 341f044ba4267e68cbefd7b84a6cf4ca 195 Gene3D G3DSA:1.10.357.10 52 194 1.2E-28 T 12-10-2018 TL08_24245 341f044ba4267e68cbefd7b84a6cf4ca 195 SUPERFAMILY SSF46689 3 67 3.64E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_24245 341f044ba4267e68cbefd7b84a6cf4ca 195 Gene3D G3DSA:1.10.10.60 1 51 7.6E-13 T 12-10-2018 TL08_24245 341f044ba4267e68cbefd7b84a6cf4ca 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 51 6.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16490 ab7249cb0e2afa17a18e00796d39d8f2 268 SUPERFAMILY SSF46785 19 79 2.31E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16490 ab7249cb0e2afa17a18e00796d39d8f2 268 Pfam PF00455 DeoR C terminal sensor domain 91 248 5.4E-40 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain TL08_16490 ab7249cb0e2afa17a18e00796d39d8f2 268 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 54 3.8E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_16490 ab7249cb0e2afa17a18e00796d39d8f2 268 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 54 72 3.8E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_16490 ab7249cb0e2afa17a18e00796d39d8f2 268 SUPERFAMILY SSF100950 90 249 2.72E-24 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_16490 ab7249cb0e2afa17a18e00796d39d8f2 268 SMART SM00420 22 74 2.9E-12 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_16490 ab7249cb0e2afa17a18e00796d39d8f2 268 Pfam PF08220 DeoR-like helix-turn-helix domain 22 74 3.4E-13 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_16490 ab7249cb0e2afa17a18e00796d39d8f2 268 SMART SM01134 89 249 4.5E-55 T 12-10-2018 TL08_12130 7f8579221e3262b149fbbc0ec0465f7f 326 Gene3D G3DSA:1.10.150.20 203 272 9.5E-15 T 12-10-2018 TL08_12130 7f8579221e3262b149fbbc0ec0465f7f 326 SUPERFAMILY SSF47807 204 317 2.39E-19 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TL08_12130 7f8579221e3262b149fbbc0ec0465f7f 326 SMART SM00279 201 236 5.5E-10 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TL08_12130 7f8579221e3262b149fbbc0ec0465f7f 326 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 203 290 4.3E-17 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 TL08_12130 7f8579221e3262b149fbbc0ec0465f7f 326 SMART SM00475 3 293 1.8E-74 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 TL08_12130 7f8579221e3262b149fbbc0ec0465f7f 326 SUPERFAMILY SSF88723 4 175 6.21E-36 T 12-10-2018 IPR029060 PIN-like domain superfamily TL08_12130 7f8579221e3262b149fbbc0ec0465f7f 326 Gene3D G3DSA:3.40.50.1010 1 195 2.1E-42 T 12-10-2018 TL08_12130 7f8579221e3262b149fbbc0ec0465f7f 326 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 193 1.1E-44 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 TL08_02090 a7002cc8e33d34a0f439247f71e0f9b6 228 SUPERFAMILY SSF51391 8 220 9.68E-59 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TL08_02090 a7002cc8e33d34a0f439247f71e0f9b6 228 Gene3D G3DSA:3.20.20.70 4 225 7.9E-69 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_02090 a7002cc8e33d34a0f439247f71e0f9b6 228 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 14 218 1.8E-58 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TL08_02090 a7002cc8e33d34a0f439247f71e0f9b6 228 Pfam PF02581 Thiamine monophosphate synthase 15 205 1.2E-50 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TL08_02090 a7002cc8e33d34a0f439247f71e0f9b6 228 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 12 223 24.907 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TL08_23275 cba891617d676dd24c01b492201e5296 391 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 174 273 2.1E-17 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain TL08_23275 cba891617d676dd24c01b492201e5296 391 SUPERFAMILY SSF52266 167 377 7.19E-24 T 12-10-2018 TL08_23275 cba891617d676dd24c01b492201e5296 391 Gene3D G3DSA:3.40.50.1110 168 383 6.6E-68 T 12-10-2018 IPR036514 SGNH hydrolase superfamily TL08_23275 cba891617d676dd24c01b492201e5296 391 Gene3D G3DSA:2.60.120.260 4 161 2.8E-40 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_05980 d64ed3ff41b593c92fa5f7876b3fadb3 383 PRINTS PR00359 B-class P450 signature 319 328 1.5E-10 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05980 d64ed3ff41b593c92fa5f7876b3fadb3 383 PRINTS PR00359 B-class P450 signature 328 339 1.5E-10 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05980 d64ed3ff41b593c92fa5f7876b3fadb3 383 PRINTS PR00359 B-class P450 signature 142 158 1.5E-10 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05980 d64ed3ff41b593c92fa5f7876b3fadb3 383 PRINTS PR00359 B-class P450 signature 95 106 1.5E-10 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_05980 d64ed3ff41b593c92fa5f7876b3fadb3 383 Gene3D G3DSA:1.10.630.10 10 382 4.9E-60 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_05980 d64ed3ff41b593c92fa5f7876b3fadb3 383 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 321 330 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_05980 d64ed3ff41b593c92fa5f7876b3fadb3 383 SUPERFAMILY SSF48264 23 363 1.14E-48 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_23185 6ba6a8344226e9e6cc0d0516d101f08c 212 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 16 204 1.1E-106 T 12-10-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_23185 6ba6a8344226e9e6cc0d0516d101f08c 212 SUPERFAMILY SSF88946 25 109 2.33E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TL08_23185 6ba6a8344226e9e6cc0d0516d101f08c 212 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 192 7.0E-28 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TL08_23185 6ba6a8344226e9e6cc0d0516d101f08c 212 Gene3D G3DSA:1.10.10.10 129 197 5.5E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23185 6ba6a8344226e9e6cc0d0516d101f08c 212 Gene3D G3DSA:1.10.1740.10 18 99 4.0E-34 T 12-10-2018 TL08_23185 6ba6a8344226e9e6cc0d0516d101f08c 212 SUPERFAMILY SSF88659 135 193 1.68E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TL08_23185 6ba6a8344226e9e6cc0d0516d101f08c 212 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 51 82 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_23185 6ba6a8344226e9e6cc0d0516d101f08c 212 Pfam PF08281 Sigma-70, region 4 137 188 1.0E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TL08_23185 6ba6a8344226e9e6cc0d0516d101f08c 212 Pfam PF04542 Sigma-70 region 2 33 96 1.2E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TL08_13805 2aa739e99916447cdf538be80e260195 342 Pfam PF13354 Beta-lactamase enzyme family 90 285 2.3E-33 T 12-10-2018 TL08_13805 2aa739e99916447cdf538be80e260195 342 Gene3D G3DSA:3.40.710.10 27 311 1.5E-32 T 12-10-2018 TL08_13805 2aa739e99916447cdf538be80e260195 342 SUPERFAMILY SSF56601 75 295 5.64E-23 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_17465 576fe7e4dfa9870fabcf5d6dfbb340b7 146 SUPERFAMILY SSF160719 22 130 5.75E-34 T 12-10-2018 TL08_17465 576fe7e4dfa9870fabcf5d6dfbb340b7 146 Gene3D G3DSA:3.10.450.40 1 130 7.5E-49 T 12-10-2018 TL08_17465 576fe7e4dfa9870fabcf5d6dfbb340b7 146 Pfam PF04965 Gene 25-like lysozyme 27 116 1.1E-24 T 12-10-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD TL08_16785 0076a7656cb11713102dfb19586c14ee 137 Pfam PF13569 Domain of unknown function (DUF4132) 1 58 6.8E-13 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_01145 c0fa7f0aebd6dda8a48712e64bfd40b6 150 Gene3D G3DSA:3.30.1490.190 97 150 6.0E-12 T 12-10-2018 TL08_01145 c0fa7f0aebd6dda8a48712e64bfd40b6 150 SUPERFAMILY SSF46785 18 145 9.09E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_01145 c0fa7f0aebd6dda8a48712e64bfd40b6 150 Gene3D G3DSA:1.10.10.10 16 94 1.4E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_01145 c0fa7f0aebd6dda8a48712e64bfd40b6 150 Pfam PF01475 Ferric uptake regulator family 25 114 1.5E-18 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TL08_06700 b5e1c0960156004cee2069529cd26b3e 472 Pfam PF13193 AMP-binding enzyme C-terminal domain 388 455 2.0E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_06700 b5e1c0960156004cee2069529cd26b3e 472 SUPERFAMILY SSF56801 24 458 1.01E-75 T 12-10-2018 TL08_06700 b5e1c0960156004cee2069529cd26b3e 472 Gene3D G3DSA:3.40.50.12780 13 375 6.1E-48 T 12-10-2018 TL08_06700 b5e1c0960156004cee2069529cd26b3e 472 Gene3D G3DSA:3.30.300.30 376 468 2.4E-13 T 12-10-2018 TL08_06700 b5e1c0960156004cee2069529cd26b3e 472 Pfam PF00501 AMP-binding enzyme 34 379 1.4E-36 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_19440 ce04f4a8bcae800c02db3b48bd2e9dc4 818 SUPERFAMILY SSF144091 4 198 1.22E-11 T 12-10-2018 TL08_19440 ce04f4a8bcae800c02db3b48bd2e9dc4 818 Gene3D G3DSA:1.20.1540.10 1 223 9.4E-6 T 12-10-2018 IPR035952 Rhomboid-like superfamily TL08_19440 ce04f4a8bcae800c02db3b48bd2e9dc4 818 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 484 780 1.9E-90 T 12-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal TL08_03450 5d265076fcf97fe15f797b09bd39a9ac 334 Gene3D G3DSA:3.40.50.720 1 150 2.3E-17 T 12-10-2018 TL08_03450 5d265076fcf97fe15f797b09bd39a9ac 334 SUPERFAMILY SSF51735 1 143 4.55E-13 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_03450 5d265076fcf97fe15f797b09bd39a9ac 334 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 82 2.8E-5 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_20860 2b20c07d096367792ade9286adaf674a 411 TIGRFAM TIGR03187 DGQHR: DGQHR domain 21 303 1.5E-16 T 12-10-2018 IPR017601 DGQHR-containing domain TL08_20860 2b20c07d096367792ade9286adaf674a 411 Pfam PF14072 DNA-sulfur modification-associated 21 343 1.2E-29 T 12-10-2018 IPR017642 DNA sulphur modification protein DndB TL08_06470 102dd170cd904eda31b479be8c523597 435 SUPERFAMILY SSF54675 8 138 1.51E-38 T 12-10-2018 TL08_06470 102dd170cd904eda31b479be8c523597 435 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 371 1.1E-129 T 12-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 TL08_06470 102dd170cd904eda31b479be8c523597 435 PIRSF PIRSF000484 5 430 2.5E-95 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TL08_06470 102dd170cd904eda31b479be8c523597 435 Gene3D G3DSA:3.20.140.10 12 369 3.9E-99 T 12-10-2018 TL08_06470 102dd170cd904eda31b479be8c523597 435 Gene3D G3DSA:3.20.20.70 153 312 3.9E-99 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_06470 102dd170cd904eda31b479be8c523597 435 SUPERFAMILY SSF51690 141 430 9.86E-85 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TL08_06470 102dd170cd904eda31b479be8c523597 435 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 141 310 1.1E-5 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TL08_18225 4eec2628f0514453952f8586965ce230 225 SUPERFAMILY SSF56281 26 221 3.08E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_18225 4eec2628f0514453952f8586965ce230 225 Gene3D G3DSA:3.60.15.10 23 223 1.2E-47 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_18225 4eec2628f0514453952f8586965ce230 225 Pfam PF00753 Metallo-beta-lactamase superfamily 33 204 1.5E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_18225 4eec2628f0514453952f8586965ce230 225 SMART SM00849 36 204 1.3E-28 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_06420 c84b328bb2c99d05759becd27848d934 273 Gene3D G3DSA:3.40.50.150 7 273 4.6E-104 T 12-10-2018 TL08_06420 c84b328bb2c99d05759becd27848d934 273 SUPERFAMILY SSF53335 21 251 4.22E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_06420 c84b328bb2c99d05759becd27848d934 273 Pfam PF04672 S-adenosyl methyltransferase 12 272 1.8E-92 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_06420 c84b328bb2c99d05759becd27848d934 273 PIRSF PIRSF017393 4 273 3.3E-93 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_19145 f39d581a086cbb8c4b0ef7d75bc7a576 291 Gene3D G3DSA:3.60.15.10 29 241 1.3E-35 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_19145 f39d581a086cbb8c4b0ef7d75bc7a576 291 SUPERFAMILY SSF56281 10 243 3.28E-33 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_19145 f39d581a086cbb8c4b0ef7d75bc7a576 291 SMART SM00849 31 225 8.3E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_19145 f39d581a086cbb8c4b0ef7d75bc7a576 291 Pfam PF00753 Metallo-beta-lactamase superfamily 28 225 3.2E-16 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_18040 d89d3b13a4f593d1e08bdec158b084db 297 Hamap MF_00361 NAD kinase [nadK]. 3 286 27.729 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TL08_18040 d89d3b13a4f593d1e08bdec158b084db 297 Gene3D G3DSA:3.40.50.10330 58 284 5.6E-88 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TL08_18040 d89d3b13a4f593d1e08bdec158b084db 297 SUPERFAMILY SSF111331 4 292 1.1E-74 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TL08_18040 d89d3b13a4f593d1e08bdec158b084db 297 Gene3D G3DSA:2.60.200.30 127 263 5.6E-88 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TL08_18040 d89d3b13a4f593d1e08bdec158b084db 297 Pfam PF01513 ATP-NAD kinase 56 270 1.4E-58 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TL08_11025 db8c8aaa929770eaa8fe24c1464b64f8 561 SMART SM00482 320 515 1.3E-10 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_11025 db8c8aaa929770eaa8fe24c1464b64f8 561 SUPERFAMILY SSF56672 163 556 3.78E-62 T 12-10-2018 TL08_11025 db8c8aaa929770eaa8fe24c1464b64f8 561 PRINTS PR00868 DNA-polymerase family A (pol I) signature 469 485 9.3E-5 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_11025 db8c8aaa929770eaa8fe24c1464b64f8 561 PRINTS PR00868 DNA-polymerase family A (pol I) signature 498 511 9.3E-5 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_11025 db8c8aaa929770eaa8fe24c1464b64f8 561 PRINTS PR00868 DNA-polymerase family A (pol I) signature 334 357 9.3E-5 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_11025 db8c8aaa929770eaa8fe24c1464b64f8 561 Gene3D G3DSA:3.30.70.370 306 533 1.7E-26 T 12-10-2018 TL08_11025 db8c8aaa929770eaa8fe24c1464b64f8 561 Gene3D G3DSA:1.10.150.20 343 476 1.7E-26 T 12-10-2018 TL08_11025 db8c8aaa929770eaa8fe24c1464b64f8 561 Pfam PF00476 DNA polymerase family A 230 533 1.2E-29 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TL08_03010 bdf9da019df8471f30a430aac20fd378 144 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 22 124 1.7E-46 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03010 bdf9da019df8471f30a430aac20fd378 144 Pfam PF00237 Ribosomal protein L22p/L17e 22 124 1.4E-35 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TL08_03010 bdf9da019df8471f30a430aac20fd378 144 SUPERFAMILY SSF54843 12 128 1.01E-42 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TL08_03010 bdf9da019df8471f30a430aac20fd378 144 ProSitePatterns PS00464 Ribosomal protein L22 signature. 100 124 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03010 bdf9da019df8471f30a430aac20fd378 144 Gene3D G3DSA:3.90.470.10 17 141 4.5E-48 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TL08_03010 bdf9da019df8471f30a430aac20fd378 144 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 18 127 29.439 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_10690 852251ee4a1136bd38fd65b356c52405 767 PIRSF PIRSF000382 9 767 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TL08_10690 852251ee4a1136bd38fd65b356c52405 767 SUPERFAMILY SSF51726 12 395 2.09E-89 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TL08_10690 852251ee4a1136bd38fd65b356c52405 767 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 15 763 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TL08_10690 852251ee4a1136bd38fd65b356c52405 767 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 13 321 5.2E-106 T 12-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TL08_10690 852251ee4a1136bd38fd65b356c52405 767 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 10 764 33.751 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TL08_10690 852251ee4a1136bd38fd65b356c52405 767 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 437 759 9.3E-147 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TL08_10690 852251ee4a1136bd38fd65b356c52405 767 Gene3D G3DSA:3.20.20.210 14 530 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TL08_10690 852251ee4a1136bd38fd65b356c52405 767 SUPERFAMILY SSF51726 415 762 4.58E-110 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TL08_10690 852251ee4a1136bd38fd65b356c52405 767 Gene3D G3DSA:3.20.20.210 396 761 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TL08_25685 614caca4dbf52d055919a7dd32090183 417 Pfam PF08484 C-methyltransferase C-terminal domain 243 401 1.5E-57 T 12-10-2018 IPR013691 C-methyltransferase TL08_25685 614caca4dbf52d055919a7dd32090183 417 Gene3D G3DSA:2.20.25.520 1 54 1.5E-15 T 12-10-2018 IPR038576 Methyltransferase putative zinc binding domain superfamily TL08_25685 614caca4dbf52d055919a7dd32090183 417 Pfam PF08421 Putative zinc binding domain 3 64 2.3E-21 T 12-10-2018 IPR013630 Methyltransferase putative zinc binding domain TL08_25685 614caca4dbf52d055919a7dd32090183 417 Gene3D G3DSA:3.40.50.150 60 254 2.3E-40 T 12-10-2018 TL08_25685 614caca4dbf52d055919a7dd32090183 417 SUPERFAMILY SSF53335 61 250 1.23E-22 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_25685 614caca4dbf52d055919a7dd32090183 417 Pfam PF13489 Methyltransferase domain 79 237 3.6E-11 T 12-10-2018 TL08_25685 614caca4dbf52d055919a7dd32090183 417 Gene3D G3DSA:3.40.50.720 308 411 1.4E-36 T 12-10-2018 TL08_07460 3c14e7c2f06de63426fcb76ebf81f78a 150 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 12 143 1.1E-35 T 12-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 TL08_07460 3c14e7c2f06de63426fcb76ebf81f78a 150 Gene3D G3DSA:3.10.180.10 5 144 1.3E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_07460 3c14e7c2f06de63426fcb76ebf81f78a 150 SUPERFAMILY SSF54593 9 146 2.2E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_07460 3c14e7c2f06de63426fcb76ebf81f78a 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 124 3.5E-19 T 12-10-2018 TL08_08145 cf890584045f59db4876ef12b3fa6b2f 468 SUPERFAMILY SSF52743 143 467 3.8E-63 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_08145 cf890584045f59db4876ef12b3fa6b2f 468 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 197 207 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_08145 cf890584045f59db4876ef12b3fa6b2f 468 Gene3D G3DSA:3.40.50.200 84 468 2.0E-70 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_08145 cf890584045f59db4876ef12b3fa6b2f 468 Pfam PF00082 Subtilase family 149 435 2.5E-41 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_08145 cf890584045f59db4876ef12b3fa6b2f 468 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 389 399 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_08145 cf890584045f59db4876ef12b3fa6b2f 468 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 152 163 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TL08_08145 cf890584045f59db4876ef12b3fa6b2f 468 PRINTS PR00723 Subtilisin serine protease family (S8) signature 193 206 1.0E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_08145 cf890584045f59db4876ef12b3fa6b2f 468 PRINTS PR00723 Subtilisin serine protease family (S8) signature 388 404 1.0E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_08145 cf890584045f59db4876ef12b3fa6b2f 468 PRINTS PR00723 Subtilisin serine protease family (S8) signature 147 166 1.0E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_12970 a98b40203533146d3bfc229dee1df68b 229 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 15 168 2.6E-22 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 TL08_12970 a98b40203533146d3bfc229dee1df68b 229 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 16 54 6.3E-13 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal TL08_12970 a98b40203533146d3bfc229dee1df68b 229 TIGRFAM TIGR01876 cas_Cas5d: CRISPR-associated protein Cas5, subtype I-C/DVULG 16 214 3.8E-33 T 12-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 TL08_12970 a98b40203533146d3bfc229dee1df68b 229 Gene3D G3DSA:3.30.70.2660 8 219 2.9E-66 T 12-10-2018 TL08_12970 a98b40203533146d3bfc229dee1df68b 229 PIRSF PIRSF029950 5 225 2.3E-54 T 12-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 TL08_09525 5a07cb3e225176f369de14c0d0759f49 491 SUPERFAMILY SSF53067 6 248 5.72E-71 T 12-10-2018 TL08_09525 5a07cb3e225176f369de14c0d0759f49 491 PIRSF PIRSF000538 3 476 8.8E-135 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TL08_09525 5a07cb3e225176f369de14c0d0759f49 491 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 245 6.7E-62 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TL08_09525 5a07cb3e225176f369de14c0d0759f49 491 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 440 2.4E-24 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TL08_09525 5a07cb3e225176f369de14c0d0759f49 491 Gene3D G3DSA:3.30.420.40 248 474 3.7E-54 T 12-10-2018 TL08_09525 5a07cb3e225176f369de14c0d0759f49 491 TIGRFAM TIGR01312 XylB: xylulokinase 7 455 4.4E-116 T 12-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 TL08_09525 5a07cb3e225176f369de14c0d0759f49 491 SUPERFAMILY SSF53067 250 443 1.94E-41 T 12-10-2018 TL08_09525 5a07cb3e225176f369de14c0d0759f49 491 Gene3D G3DSA:3.30.420.40 2 246 1.6E-79 T 12-10-2018 TL08_00060 4027c9f8b627cbe78d40ca6b9cd5318a 155 SUPERFAMILY SSF159888 51 152 1.24E-10 T 12-10-2018 TL08_07695 c88dec19c998d6b1de9eab6af65bdfe3 85 Gene3D G3DSA:1.10.10.1150 5 84 1.1E-8 T 12-10-2018 TL08_07695 c88dec19c998d6b1de9eab6af65bdfe3 85 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 18 83 1.4E-13 T 12-10-2018 IPR008792 Coenzyme PQQ synthesis D TL08_05495 404a762283c995b56571b3f496eb08d0 294 SMART SM00382 31 217 2.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_05495 404a762283c995b56571b3f496eb08d0 294 SUPERFAMILY SSF52540 5 221 2.72E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05495 404a762283c995b56571b3f496eb08d0 294 Pfam PF00005 ABC transporter 23 159 1.6E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05495 404a762283c995b56571b3f496eb08d0 294 Gene3D G3DSA:3.40.50.300 1 224 1.6E-61 T 12-10-2018 TL08_05495 404a762283c995b56571b3f496eb08d0 294 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 Gene3D G3DSA:3.40.190.10 166 273 5.1E-50 T 12-10-2018 TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 SUPERFAMILY SSF46785 6 90 4.77E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 Gene3D G3DSA:1.10.10.10 2 89 3.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 Gene3D G3DSA:3.40.190.10 92 291 5.1E-50 T 12-10-2018 TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 Pfam PF03466 LysR substrate binding domain 91 292 3.9E-34 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.3E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19665 a945cf7e7eacd49103ab6bdc0cfc5069 296 SUPERFAMILY SSF53850 92 292 1.99E-29 T 12-10-2018 TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 Gene3D G3DSA:3.20.20.70 20 512 7.0E-204 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 PIRSF PIRSF000130 20 513 5.4E-195 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 SUPERFAMILY SSF51412 24 192 5.77E-28 T 12-10-2018 TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 Pfam PF00571 CBS domain 113 161 4.2E-8 T 12-10-2018 IPR000644 CBS domain TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 Pfam PF00571 CBS domain 169 222 8.9E-7 T 12-10-2018 IPR000644 CBS domain TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 SMART SM00116 177 225 2.4E-7 T 12-10-2018 IPR000644 CBS domain TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 SMART SM00116 116 164 9.9E-7 T 12-10-2018 IPR000644 CBS domain TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 315 327 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 28 512 81.728 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 28 481 5.6E-179 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 SMART SM01240 27 499 3.9E-301 T 12-10-2018 TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 SUPERFAMILY SSF51412 138 510 1.02E-111 T 12-10-2018 TL08_24770 ff9a4d29eaec1f9956c49ecc43ccfece 513 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 28 499 3.0E-152 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TL08_06225 21a6ac689159c43af30a591b013adbb8 253 SMART SM00866 90 229 3.5E-28 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_06225 21a6ac689159c43af30a591b013adbb8 253 Gene3D G3DSA:1.10.10.10 1 74 5.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06225 21a6ac689159c43af30a591b013adbb8 253 SUPERFAMILY SSF46785 3 59 5.45E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_06225 21a6ac689159c43af30a591b013adbb8 253 Pfam PF07702 UTRA domain 92 226 1.1E-28 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_06225 21a6ac689159c43af30a591b013adbb8 253 SUPERFAMILY SSF64288 63 236 3.3E-37 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_06225 21a6ac689159c43af30a591b013adbb8 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 58 5.2E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_06225 21a6ac689159c43af30a591b013adbb8 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 5.3E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_06225 21a6ac689159c43af30a591b013adbb8 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 5.3E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_06225 21a6ac689159c43af30a591b013adbb8 253 SMART SM00345 9 69 9.7E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_06225 21a6ac689159c43af30a591b013adbb8 253 Gene3D G3DSA:3.40.1410.10 76 238 7.3E-35 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 SUPERFAMILY SSF46955 11 131 4.03E-27 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 SMART SM00422 11 79 1.4E-25 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 149 3.1E-68 T 12-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 Pfam PF09278 MerR, DNA binding 53 118 7.2E-18 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 8.4E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 8.4E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 8.4E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 ProSitePatterns PS00552 MerR-type HTH domain signature. 14 36 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 Gene3D G3DSA:1.10.1660.10 5 134 5.9E-33 T 12-10-2018 TL08_13035 1485684e044dea0a9b37c5e4cd7533ea 182 Pfam PF00376 MerR family regulatory protein 12 48 4.5E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_25730 1543d9a3766edac8e2d504d9903af4b4 133 Gene3D G3DSA:3.10.450.50 21 133 2.0E-32 T 12-10-2018 TL08_25730 1543d9a3766edac8e2d504d9903af4b4 133 Pfam PF14534 Domain of unknown function (DUF4440) 23 123 2.2E-9 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 TL08_25730 1543d9a3766edac8e2d504d9903af4b4 133 SUPERFAMILY SSF54427 23 131 8.13E-21 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_02520 f4eb6a7595a102de87669c7830f7ac5f 392 SUPERFAMILY SSF56801 24 388 2.22E-75 T 12-10-2018 TL08_02520 f4eb6a7595a102de87669c7830f7ac5f 392 Pfam PF00501 AMP-binding enzyme 36 291 6.8E-38 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_02520 f4eb6a7595a102de87669c7830f7ac5f 392 ProSitePatterns PS00455 Putative AMP-binding domain signature. 61 72 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_02520 f4eb6a7595a102de87669c7830f7ac5f 392 Gene3D G3DSA:3.40.50.12780 2 287 5.9E-51 T 12-10-2018 TL08_02520 f4eb6a7595a102de87669c7830f7ac5f 392 Pfam PF13193 AMP-binding enzyme C-terminal domain 301 376 2.3E-18 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_02520 f4eb6a7595a102de87669c7830f7ac5f 392 Gene3D G3DSA:3.30.300.30 288 387 1.1E-23 T 12-10-2018 TL08_16430 eeb44493a44c545593a744c2cb1a79c2 65 Pfam PF04149 Domain of unknown function (DUF397) 8 60 2.4E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_09060 d5a77e64a0968d8fbebb4a29c6f523a5 196 Gene3D G3DSA:1.10.357.10 4 196 5.5E-48 T 12-10-2018 TL08_09060 d5a77e64a0968d8fbebb4a29c6f523a5 196 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 89 193 5.5E-18 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal TL08_09060 d5a77e64a0968d8fbebb4a29c6f523a5 196 SUPERFAMILY SSF48498 86 193 1.48E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_09060 d5a77e64a0968d8fbebb4a29c6f523a5 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.9E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_09060 d5a77e64a0968d8fbebb4a29c6f523a5 196 SUPERFAMILY SSF46689 4 70 2.36E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_26260 fa2f4058b6008b8b3f44d2ccfea432f3 343 Pfam PF02898 Nitric oxide synthase, oxygenase domain 20 328 1.4E-95 T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 TL08_26260 fa2f4058b6008b8b3f44d2ccfea432f3 343 Gene3D G3DSA:3.90.1230.10 207 313 5.1E-98 T 12-10-2018 TL08_26260 fa2f4058b6008b8b3f44d2ccfea432f3 343 Gene3D G3DSA:3.90.440.10 93 206 5.1E-98 T 12-10-2018 TL08_26260 fa2f4058b6008b8b3f44d2ccfea432f3 343 Gene3D G3DSA:3.90.340.10 20 328 5.1E-98 T 12-10-2018 TL08_26260 fa2f4058b6008b8b3f44d2ccfea432f3 343 SUPERFAMILY SSF56512 19 334 6.54E-100 T 12-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 TL08_24965 5f622e28bcd548cbcfce9c36f1efe0c5 441 Gene3D G3DSA:1.10.287.1060 127 211 5.1E-9 T 12-10-2018 TL08_24965 5f622e28bcd548cbcfce9c36f1efe0c5 441 SUPERFAMILY SSF140453 130 205 1.11E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_12315 91a04b2e1690566ddb33e4794d4fb06c 266 Pfam PF04672 S-adenosyl methyltransferase 8 265 9.7E-92 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_12315 91a04b2e1690566ddb33e4794d4fb06c 266 PIRSF PIRSF017393 1 266 6.6E-97 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_12315 91a04b2e1690566ddb33e4794d4fb06c 266 Gene3D G3DSA:3.40.50.150 1 266 5.9E-106 T 12-10-2018 TL08_12315 91a04b2e1690566ddb33e4794d4fb06c 266 SUPERFAMILY SSF53335 10 245 6.0E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_08015 062a7eecdb9528564340e542f572b06b 264 Gene3D G3DSA:3.40.80.10 3 162 3.3E-29 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_08015 062a7eecdb9528564340e542f572b06b 264 SUPERFAMILY SSF47090 188 245 1.61E-9 T 12-10-2018 IPR036365 PGBD-like superfamily TL08_08015 062a7eecdb9528564340e542f572b06b 264 Pfam PF01471 Putative peptidoglycan binding domain 192 244 7.2E-9 T 12-10-2018 IPR002477 Peptidoglycan binding-like TL08_08015 062a7eecdb9528564340e542f572b06b 264 SUPERFAMILY SSF55846 3 161 8.78E-26 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_08015 062a7eecdb9528564340e542f572b06b 264 SMART SM00701 2 133 2.1E-4 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_08015 062a7eecdb9528564340e542f572b06b 264 Gene3D G3DSA:1.10.101.10 184 248 6.5E-13 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TL08_26455 a05d090486fe500632f3c8b4da6e53cf 404 Pfam PF07687 Peptidase dimerisation domain 196 302 1.3E-12 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TL08_26455 a05d090486fe500632f3c8b4da6e53cf 404 SUPERFAMILY SSF53187 20 402 9.43E-38 T 12-10-2018 TL08_26455 a05d090486fe500632f3c8b4da6e53cf 404 Gene3D G3DSA:3.30.70.360 199 318 7.2E-59 T 12-10-2018 TL08_26455 a05d090486fe500632f3c8b4da6e53cf 404 Gene3D G3DSA:3.40.630.10 27 389 7.2E-59 T 12-10-2018 TL08_26455 a05d090486fe500632f3c8b4da6e53cf 404 SUPERFAMILY SSF55031 198 303 1.15E-11 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TL08_26455 a05d090486fe500632f3c8b4da6e53cf 404 Pfam PF01546 Peptidase family M20/M25/M40 93 398 1.0E-20 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TL08_21615 3abd3c64c542869736af2843a5e7b6d2 347 SMART SM00701 148 306 4.6E-9 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_21615 3abd3c64c542869736af2843a5e7b6d2 347 SUPERFAMILY SSF55846 149 342 2.88E-39 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_21615 3abd3c64c542869736af2843a5e7b6d2 347 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 171 328 1.3E-13 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_21615 3abd3c64c542869736af2843a5e7b6d2 347 Gene3D G3DSA:3.40.80.10 143 344 1.8E-47 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 SUPERFAMILY SSF52172 15 147 4.27E-32 T 12-10-2018 IPR011006 CheY-like superfamily TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 ProSitePatterns PS00622 LuxR-type HTH domain signature. 182 209 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 Gene3D G3DSA:3.40.50.12740 16 228 1.4E-65 T 12-10-2018 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 SMART SM00448 16 129 1.5E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 222 4.5E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 198 8.3E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 210 8.3E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 182 8.3E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 SMART SM00421 165 222 6.9E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 SUPERFAMILY SSF46894 151 229 2.41E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_07090 f6ea801e89e4b5b4bac88dc32d26e463 242 Pfam PF00072 Response regulator receiver domain 18 129 5.9E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_00715 f51224e119e536da323660fb91e6cb50 272 SUPERFAMILY SSF52540 42 243 1.12E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_00715 f51224e119e536da323660fb91e6cb50 272 Pfam PF00005 ABC transporter 47 177 3.1E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_00715 f51224e119e536da323660fb91e6cb50 272 Gene3D G3DSA:3.40.50.300 34 262 3.0E-42 T 12-10-2018 TL08_00715 f51224e119e536da323660fb91e6cb50 272 SMART SM00382 56 228 1.7E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_02435 daa920daff9598e44a5b58811540878b 197 ProSitePatterns PS00194 Thioredoxin family active site. 83 101 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TL08_02435 daa920daff9598e44a5b58811540878b 197 Pfam PF00578 AhpC/TSA family 55 175 1.0E-15 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TL08_02435 daa920daff9598e44a5b58811540878b 197 Gene3D G3DSA:3.40.30.10 46 195 9.6E-34 T 12-10-2018 TL08_02435 daa920daff9598e44a5b58811540878b 197 SUPERFAMILY SSF52833 54 196 2.58E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_08230 b43eabc952eb2d38a83145b32d299e78 141 SUPERFAMILY SSF81301 8 117 5.89E-39 T 12-10-2018 TL08_08230 b43eabc952eb2d38a83145b32d299e78 141 Gene3D G3DSA:3.30.460.10 1 112 4.8E-40 T 12-10-2018 TL08_08230 b43eabc952eb2d38a83145b32d299e78 141 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 109 23.597 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TL08_08230 b43eabc952eb2d38a83145b32d299e78 141 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 14 108 5.2E-32 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TL08_08230 b43eabc952eb2d38a83145b32d299e78 141 Pfam PF02410 Ribosomal silencing factor during starvation 15 108 3.3E-23 T 12-10-2018 TL08_00495 b3c99aad926a2c40eb44f1e253518806 202 SUPERFAMILY SSF48498 86 200 6.4E-28 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_00495 b3c99aad926a2c40eb44f1e253518806 202 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 114 198 2.2E-7 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal TL08_00495 b3c99aad926a2c40eb44f1e253518806 202 Gene3D G3DSA:1.10.357.10 75 201 2.7E-32 T 12-10-2018 TL08_00495 b3c99aad926a2c40eb44f1e253518806 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TL08_00495 b3c99aad926a2c40eb44f1e253518806 202 Gene3D G3DSA:1.10.10.60 6 74 2.6E-28 T 12-10-2018 TL08_00495 b3c99aad926a2c40eb44f1e253518806 202 SUPERFAMILY SSF46689 8 83 2.15E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_00495 b3c99aad926a2c40eb44f1e253518806 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 1.2E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_18440 38c8265166c5ea0fe732da18d3572c6c 637 Pfam PF00326 Prolyl oligopeptidase family 418 632 4.3E-44 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_18440 38c8265166c5ea0fe732da18d3572c6c 637 Gene3D G3DSA:2.120.10.30 9 204 1.2E-15 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_18440 38c8265166c5ea0fe732da18d3572c6c 637 SUPERFAMILY SSF82171 22 358 2.51E-16 T 12-10-2018 TL08_18440 38c8265166c5ea0fe732da18d3572c6c 637 SUPERFAMILY SSF53474 278 633 1.42E-70 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18440 38c8265166c5ea0fe732da18d3572c6c 637 Gene3D G3DSA:3.40.50.1820 350 636 1.3E-76 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_12435 0285b1206664463d2d6685792fe5e218 500 Gene3D G3DSA:3.40.50.300 3 242 7.3E-59 T 12-10-2018 TL08_12435 0285b1206664463d2d6685792fe5e218 500 Gene3D G3DSA:3.40.50.300 262 497 9.9E-40 T 12-10-2018 TL08_12435 0285b1206664463d2d6685792fe5e218 500 SMART SM00382 33 221 3.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12435 0285b1206664463d2d6685792fe5e218 500 SMART SM00382 284 477 0.11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12435 0285b1206664463d2d6685792fe5e218 500 SUPERFAMILY SSF52540 10 229 4.46E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12435 0285b1206664463d2d6685792fe5e218 500 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12435 0285b1206664463d2d6685792fe5e218 500 Pfam PF00005 ABC transporter 277 429 1.5E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12435 0285b1206664463d2d6685792fe5e218 500 Pfam PF00005 ABC transporter 24 173 5.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12435 0285b1206664463d2d6685792fe5e218 500 SUPERFAMILY SSF52540 274 484 4.07E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23495 de67763218b8beb0db5ae03c196deb30 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 327 3.1E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 305 321 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 Gene3D G3DSA:1.20.1250.20 15 452 1.7E-106 T 12-10-2018 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 SUPERFAMILY SSF103473 7 445 2.49E-64 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 113 138 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 PRINTS PR00171 Sugar transporter signature 25 35 1.4E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 PRINTS PR00171 Sugar transporter signature 260 270 1.4E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 PRINTS PR00171 Sugar transporter signature 350 371 1.4E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 PRINTS PR00171 Sugar transporter signature 108 127 1.4E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 PRINTS PR00171 Sugar transporter signature 373 385 1.4E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 Pfam PF00083 Sugar (and other) transporter 18 449 2.2E-93 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TL08_16750 bb157b9b370b2b666a6da8b12c7ad9e5 464 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 17 445 2.7E-89 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_11840 0c628f1d32242cd215973e15d13d4ba3 71 Pfam PF04149 Domain of unknown function (DUF397) 9 60 8.8E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_02175 f34cbe2addcb83b962938fcab9bb586d 118 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 116 15.455 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TL08_02175 f34cbe2addcb83b962938fcab9bb586d 118 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 111 2.8E-20 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TL08_12625 b61318362289ca79318498bb6b974dc4 252 SUPERFAMILY SSF51735 7 250 1.17E-85 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_12625 b61318362289ca79318498bb6b974dc4 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12625 b61318362289ca79318498bb6b974dc4 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12625 b61318362289ca79318498bb6b974dc4 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12625 b61318362289ca79318498bb6b974dc4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12625 b61318362289ca79318498bb6b974dc4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.2E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12625 b61318362289ca79318498bb6b974dc4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.2E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12625 b61318362289ca79318498bb6b974dc4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.2E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12625 b61318362289ca79318498bb6b974dc4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12625 b61318362289ca79318498bb6b974dc4 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.2E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12625 b61318362289ca79318498bb6b974dc4 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 1.8E-69 T 12-10-2018 TL08_12625 b61318362289ca79318498bb6b974dc4 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 4.2E-5 T 12-10-2018 TL08_12625 b61318362289ca79318498bb6b974dc4 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_12625 b61318362289ca79318498bb6b974dc4 252 Gene3D G3DSA:3.40.50.720 1 252 2.4E-87 T 12-10-2018 TL08_18450 d8298fd409f4f31b03bcf9f879f1f12e 606 Gene3D G3DSA:3.50.50.60 66 342 9.1E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_18450 d8298fd409f4f31b03bcf9f879f1f12e 606 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 74 231 7.7E-10 T 12-10-2018 TL08_18450 d8298fd409f4f31b03bcf9f879f1f12e 606 SUPERFAMILY SSF51905 73 525 8.49E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_18450 d8298fd409f4f31b03bcf9f879f1f12e 606 Gene3D G3DSA:3.50.50.60 394 599 2.2E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_22015 74b2ec1df14ddd515554bee746bb8cdd 525 SUPERFAMILY SSF50249 13 409 4.85E-88 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_22015 74b2ec1df14ddd515554bee746bb8cdd 525 Pfam PF00773 RNB domain 49 354 1.1E-41 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TL08_22015 74b2ec1df14ddd515554bee746bb8cdd 525 SMART SM00955 49 367 1.1E-59 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TL08_18795 fb794ad1302409be5359899a7a464a54 206 SUPERFAMILY SSF52540 1 201 5.66E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18795 fb794ad1302409be5359899a7a464a54 206 Gene3D G3DSA:3.40.50.300 1 203 6.6E-10 T 12-10-2018 TL08_12320 557095385f6bea93ca672ca2fe3de381 177 SUPERFAMILY SSF53271 13 163 5.68E-39 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_12320 557095385f6bea93ca672ca2fe3de381 177 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 6 172 30.778 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 TL08_12320 557095385f6bea93ca672ca2fe3de381 177 Pfam PF00156 Phosphoribosyl transferase domain 41 150 3.5E-13 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TL08_12320 557095385f6bea93ca672ca2fe3de381 177 Gene3D G3DSA:3.40.50.2020 2 173 6.4E-50 T 12-10-2018 TL08_01820 02a4615d89dfb33eecc48920e2f75927 459 SUPERFAMILY SSF47413 23 79 3.94E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_01820 02a4615d89dfb33eecc48920e2f75927 459 SMART SM00530 25 81 1.4E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_01820 02a4615d89dfb33eecc48920e2f75927 459 Pfam PF13560 Helix-turn-helix domain 23 80 1.0E-12 T 12-10-2018 TL08_01820 02a4615d89dfb33eecc48920e2f75927 459 Gene3D G3DSA:1.10.260.40 20 84 1.0E-11 T 12-10-2018 TL08_00575 5e5d0070e9e315187d1deab86c323744 416 Gene3D G3DSA:3.30.450.40 56 218 1.0E-19 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_00575 5e5d0070e9e315187d1deab86c323744 416 SMART SM00065 56 211 2.3E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 TL08_00575 5e5d0070e9e315187d1deab86c323744 416 SUPERFAMILY SSF55781 56 211 2.84E-15 T 12-10-2018 TL08_00575 5e5d0070e9e315187d1deab86c323744 416 SUPERFAMILY SSF55874 323 415 6.94E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_00575 5e5d0070e9e315187d1deab86c323744 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 414 1.9E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_00575 5e5d0070e9e315187d1deab86c323744 416 Pfam PF07730 Histidine kinase 218 284 6.7E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_00575 5e5d0070e9e315187d1deab86c323744 416 Pfam PF13185 GAF domain 56 201 2.4E-12 T 12-10-2018 IPR003018 GAF domain GO:0005515 TL08_00575 5e5d0070e9e315187d1deab86c323744 416 Gene3D G3DSA:3.30.565.10 294 415 3.6E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_27040 f5377d30c35ceefea2b4778275685e17 457 SUPERFAMILY SSF103473 69 446 3.79E-24 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_27040 f5377d30c35ceefea2b4778275685e17 457 Pfam PF05977 Transmembrane secretion effector 72 438 5.7E-9 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_27040 f5377d30c35ceefea2b4778275685e17 457 Gene3D G3DSA:1.20.1250.20 42 441 6.9E-24 T 12-10-2018 TL08_16860 3ca2d5a03f11d65828a738a6d01b35c0 436 SUPERFAMILY SSF116734 1 92 9.48E-18 T 12-10-2018 TL08_16860 3ca2d5a03f11d65828a738a6d01b35c0 436 SUPERFAMILY SSF116734 163 377 8.99E-35 T 12-10-2018 TL08_16860 3ca2d5a03f11d65828a738a6d01b35c0 436 Pfam PF01420 Type I restriction modification DNA specificity domain 1 89 6.0E-15 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TL08_16860 3ca2d5a03f11d65828a738a6d01b35c0 436 Gene3D G3DSA:3.90.220.20 1 95 5.7E-17 T 12-10-2018 TL08_16860 3ca2d5a03f11d65828a738a6d01b35c0 436 Gene3D G3DSA:3.90.220.20 158 368 3.9E-34 T 12-10-2018 TL08_01490 5d15c2afa3cfa3d55aa15f58085e7895 816 Pfam PF00271 Helicase conserved C-terminal domain 292 399 2.1E-11 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_01490 5d15c2afa3cfa3d55aa15f58085e7895 816 Gene3D G3DSA:3.40.50.300 280 424 3.8E-19 T 12-10-2018 TL08_01490 5d15c2afa3cfa3d55aa15f58085e7895 816 Gene3D G3DSA:3.40.50.300 44 246 5.4E-38 T 12-10-2018 TL08_01490 5d15c2afa3cfa3d55aa15f58085e7895 816 SMART SM00490 318 399 6.6E-13 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_01490 5d15c2afa3cfa3d55aa15f58085e7895 816 Pfam PF00270 DEAD/DEAH box helicase 65 229 1.6E-21 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_01490 5d15c2afa3cfa3d55aa15f58085e7895 816 SUPERFAMILY SSF52540 71 408 1.78E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01490 5d15c2afa3cfa3d55aa15f58085e7895 816 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 25 771 0.0 T 12-10-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria TL08_01490 5d15c2afa3cfa3d55aa15f58085e7895 816 Pfam PF09369 Domain of unknown function (DUF1998) 666 745 1.7E-18 T 12-10-2018 IPR018973 DEAD/DEAH-box helicase, putative TL08_01490 5d15c2afa3cfa3d55aa15f58085e7895 816 SMART SM00487 57 259 1.5E-26 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_26220 b69234fae078049cf704315736eaed75 322 SUPERFAMILY SSF53067 11 319 6.32E-55 T 12-10-2018 TL08_26220 b69234fae078049cf704315736eaed75 322 Pfam PF00480 ROK family 12 315 1.0E-57 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_26220 b69234fae078049cf704315736eaed75 322 Gene3D G3DSA:3.30.420.40 12 312 3.4E-77 T 12-10-2018 TL08_26220 b69234fae078049cf704315736eaed75 322 Gene3D G3DSA:3.30.420.40 148 299 3.4E-77 T 12-10-2018 TL08_20785 326a86abed93e9ed40aeea984df4b3f6 194 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 7 129 2.0E-13 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 TL08_20785 326a86abed93e9ed40aeea984df4b3f6 194 Gene3D G3DSA:1.20.120.450 3 132 7.0E-12 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_20785 326a86abed93e9ed40aeea984df4b3f6 194 SUPERFAMILY SSF109854 4 134 8.55E-19 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_20785 326a86abed93e9ed40aeea984df4b3f6 194 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 8 187 1.0E-41 T 12-10-2018 IPR017520 Conserved hypothetical protein CHP03086 TL08_20785 326a86abed93e9ed40aeea984df4b3f6 194 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 171 1.0E-19 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type TL08_07155 14f13c239b1287c576a2fa99d0bddf7a 1109 PRINTS PR00723 Subtilisin serine protease family (S8) signature 263 276 6.3E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_07155 14f13c239b1287c576a2fa99d0bddf7a 1109 PRINTS PR00723 Subtilisin serine protease family (S8) signature 439 455 6.3E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_07155 14f13c239b1287c576a2fa99d0bddf7a 1109 PRINTS PR00723 Subtilisin serine protease family (S8) signature 225 244 6.3E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_07155 14f13c239b1287c576a2fa99d0bddf7a 1109 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 440 450 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_07155 14f13c239b1287c576a2fa99d0bddf7a 1109 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 267 277 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_07155 14f13c239b1287c576a2fa99d0bddf7a 1109 Pfam PF00082 Subtilase family 225 489 2.0E-55 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_07155 14f13c239b1287c576a2fa99d0bddf7a 1109 SUPERFAMILY SSF52743 209 499 3.67E-81 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_07155 14f13c239b1287c576a2fa99d0bddf7a 1109 Gene3D G3DSA:3.40.50.200 200 501 7.8E-94 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 SUPERFAMILY SSF46565 9 109 3.66E-29 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 Gene3D G3DSA:2.60.260.20 235 279 7.4E-11 T 12-10-2018 TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 SUPERFAMILY SSF49493 286 366 4.19E-18 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 Gene3D G3DSA:1.10.287.110 7 121 1.2E-27 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 Gene3D G3DSA:2.10.230.10 161 234 1.5E-20 T 12-10-2018 TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 SUPERFAMILY SSF57938 161 236 3.92E-19 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 Pfam PF01556 DnaJ C terminal domain 147 359 8.3E-34 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 392 35.733 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 Pfam PF00226 DnaJ domain 10 72 6.4E-24 T 12-10-2018 IPR001623 DnaJ domain TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 SMART SM00271 9 67 2.0E-25 T 12-10-2018 IPR001623 DnaJ domain TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 Pfam PF00684 DnaJ central domain 174 234 7.8E-13 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 Gene3D G3DSA:2.60.260.20 281 359 3.0E-25 T 12-10-2018 TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 SUPERFAMILY SSF49493 140 293 1.28E-20 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 PRINTS PR00625 DnaJ domain signature 12 30 5.0E-20 T 12-10-2018 IPR001623 DnaJ domain TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 PRINTS PR00625 DnaJ domain signature 47 67 5.0E-20 T 12-10-2018 IPR001623 DnaJ domain TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 PRINTS PR00625 DnaJ domain signature 30 45 5.0E-20 T 12-10-2018 IPR001623 DnaJ domain TL08_26420 e214182eb8e5a028c5eab91e705c8668 396 PRINTS PR00625 DnaJ domain signature 67 86 5.0E-20 T 12-10-2018 IPR001623 DnaJ domain TL08_24960 50f3602b1c963bb7532390892fb23838 476 Gene3D G3DSA:3.40.50.200 52 413 1.9E-89 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_24960 50f3602b1c963bb7532390892fb23838 476 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 350 360 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_24960 50f3602b1c963bb7532390892fb23838 476 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 97 470 1.5E-110 T 12-10-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin TL08_24960 50f3602b1c963bb7532390892fb23838 476 PRINTS PR00723 Subtilisin serine protease family (S8) signature 108 127 3.4E-14 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_24960 50f3602b1c963bb7532390892fb23838 476 PRINTS PR00723 Subtilisin serine protease family (S8) signature 145 158 3.4E-14 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_24960 50f3602b1c963bb7532390892fb23838 476 PRINTS PR00723 Subtilisin serine protease family (S8) signature 349 365 3.4E-14 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_24960 50f3602b1c963bb7532390892fb23838 476 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 113 123 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TL08_24960 50f3602b1c963bb7532390892fb23838 476 Pfam PF00082 Subtilase family 108 401 3.0E-38 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_24960 50f3602b1c963bb7532390892fb23838 476 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 149 159 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_24960 50f3602b1c963bb7532390892fb23838 476 SUPERFAMILY SSF52743 89 410 8.77E-72 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_22725 6baefbdb802295853651af1ffc879c1a 337 Gene3D G3DSA:3.40.50.720 1 183 1.6E-78 T 12-10-2018 TL08_22725 6baefbdb802295853651af1ffc879c1a 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 6.7E-133 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TL08_22725 6baefbdb802295853651af1ffc879c1a 337 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 330 45.039 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TL08_22725 6baefbdb802295853651af1ffc879c1a 337 Gene3D G3DSA:1.10.3730.40 184 337 1.2E-69 T 12-10-2018 TL08_22725 6baefbdb802295853651af1ffc879c1a 337 SUPERFAMILY SSF48179 185 330 2.04E-66 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_22725 6baefbdb802295853651af1ffc879c1a 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 1.0E-62 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TL08_22725 6baefbdb802295853651af1ffc879c1a 337 SUPERFAMILY SSF51735 4 184 2.84E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_22725 6baefbdb802295853651af1ffc879c1a 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 2.6E-75 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TL08_22725 6baefbdb802295853651af1ffc879c1a 337 PIRSF PIRSF000116 1 209 1.7E-41 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TL08_22725 6baefbdb802295853651af1ffc879c1a 337 PIRSF PIRSF000116 204 334 1.7E-14 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TL08_25250 95d4919e78f7d4384fd9717f3071f67a 261 Pfam PF02567 Phenazine biosynthesis-like protein 8 257 9.3E-59 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TL08_25250 95d4919e78f7d4384fd9717f3071f67a 261 PIRSF PIRSF016184 1 261 9.6E-51 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TL08_25250 95d4919e78f7d4384fd9717f3071f67a 261 Gene3D G3DSA:3.10.310.10 114 249 2.1E-80 T 12-10-2018 TL08_25250 95d4919e78f7d4384fd9717f3071f67a 261 Gene3D G3DSA:3.10.310.10 6 253 2.1E-80 T 12-10-2018 TL08_25250 95d4919e78f7d4384fd9717f3071f67a 261 SUPERFAMILY SSF54506 1 259 1.57E-75 T 12-10-2018 TL08_25250 95d4919e78f7d4384fd9717f3071f67a 261 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 86 3.3E-24 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TL08_17305 f1d7d01f6bcb1f2f4502596c24eb1e85 1221 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 269 279 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_17305 f1d7d01f6bcb1f2f4502596c24eb1e85 1221 PRINTS PR00723 Subtilisin serine protease family (S8) signature 265 278 6.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_17305 f1d7d01f6bcb1f2f4502596c24eb1e85 1221 PRINTS PR00723 Subtilisin serine protease family (S8) signature 228 247 6.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_17305 f1d7d01f6bcb1f2f4502596c24eb1e85 1221 PRINTS PR00723 Subtilisin serine protease family (S8) signature 435 451 6.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_17305 f1d7d01f6bcb1f2f4502596c24eb1e85 1221 Pfam PF00082 Subtilase family 228 485 4.8E-52 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_17305 f1d7d01f6bcb1f2f4502596c24eb1e85 1221 SUPERFAMILY SSF52743 210 493 4.84E-79 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_17305 f1d7d01f6bcb1f2f4502596c24eb1e85 1221 Gene3D G3DSA:3.40.50.200 203 496 3.1E-90 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_17305 f1d7d01f6bcb1f2f4502596c24eb1e85 1221 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 436 446 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_16880 3d167993b87cd5a56927486582ec0584 290 SUPERFAMILY SSF47413 19 78 2.37E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_16880 3d167993b87cd5a56927486582ec0584 290 SMART SM00530 23 79 0.0016 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_16880 3d167993b87cd5a56927486582ec0584 290 Pfam PF13560 Helix-turn-helix domain 20 82 5.4E-9 T 12-10-2018 TL08_16880 3d167993b87cd5a56927486582ec0584 290 Gene3D G3DSA:1.10.260.40 17 81 1.9E-7 T 12-10-2018 TL08_12555 1eb6cd5ec0f66b50ecbb7b2d428fe85a 281 Gene3D G3DSA:3.40.50.720 5 256 3.4E-52 T 12-10-2018 TL08_12555 1eb6cd5ec0f66b50ecbb7b2d428fe85a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12555 1eb6cd5ec0f66b50ecbb7b2d428fe85a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12555 1eb6cd5ec0f66b50ecbb7b2d428fe85a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12555 1eb6cd5ec0f66b50ecbb7b2d428fe85a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12555 1eb6cd5ec0f66b50ecbb7b2d428fe85a 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12555 1eb6cd5ec0f66b50ecbb7b2d428fe85a 281 Pfam PF00106 short chain dehydrogenase 11 197 6.4E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12555 1eb6cd5ec0f66b50ecbb7b2d428fe85a 281 SUPERFAMILY SSF51735 5 256 4.85E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_12555 1eb6cd5ec0f66b50ecbb7b2d428fe85a 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 SUPERFAMILY SSF48256 12 434 8.5E-159 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 Gene3D G3DSA:2.20.28.60 5 55 5.8E-15 T 12-10-2018 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 PIRSF PIRSF001369 42 434 1.7E-155 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 ProSitePatterns PS00480 Citrate synthase signature. 309 321 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 20 428 4.5E-181 T 12-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 PRINTS PR00143 Citrate synthase signature 246 274 1.1E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 PRINTS PR00143 Citrate synthase signature 385 399 1.1E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 PRINTS PR00143 Citrate synthase signature 170 183 1.1E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 PRINTS PR00143 Citrate synthase signature 365 381 1.1E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 PRINTS PR00143 Citrate synthase signature 224 239 1.1E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 PRINTS PR00143 Citrate synthase signature 302 322 1.1E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 Gene3D G3DSA:1.10.580.10 62 417 5.1E-142 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 Gene3D G3DSA:1.10.230.10 273 382 5.1E-142 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain TL08_25105 ec2c91f1fdbfe1818a145d79984a6cf1 434 Pfam PF00285 Citrate synthase, C-terminal domain 51 417 3.6E-134 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_09250 c3a202547819908f9a61f1ef7bd89ed1 692 Pfam PF13699 Domain of unknown function (DUF4157) 84 153 1.8E-22 T 12-10-2018 IPR025295 Domain of unknown function DUF4157 TL08_19555 7b16239e8e63486c516c1a2973577be6 301 Pfam PF00535 Glycosyl transferase family 2 7 162 2.6E-22 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_19555 7b16239e8e63486c516c1a2973577be6 301 SUPERFAMILY SSF53448 2 230 4.31E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_19555 7b16239e8e63486c516c1a2973577be6 301 Gene3D G3DSA:3.90.550.10 1 211 2.4E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_18465 f4a64b5f9505b1d26feb9b0daf2de628 396 Pfam PF07730 Histidine kinase 192 258 7.1E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_18465 f4a64b5f9505b1d26feb9b0daf2de628 396 Gene3D G3DSA:3.30.565.10 270 391 1.3E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_18465 f4a64b5f9505b1d26feb9b0daf2de628 396 SUPERFAMILY SSF55874 303 390 1.2E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_06305 7742141047f1faa06e2b29c16611a6d5 294 Pfam PF02517 CAAX protease self-immunity 183 281 1.8E-9 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TL08_05985 46ebc59f75b9583fed951afb2df8f823 170 SMART SM00347 34 138 5.0E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_05985 46ebc59f75b9583fed951afb2df8f823 170 Gene3D G3DSA:1.10.10.10 9 155 1.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05985 46ebc59f75b9583fed951afb2df8f823 170 SUPERFAMILY SSF46785 14 150 8.41E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05985 46ebc59f75b9583fed951afb2df8f823 170 Pfam PF12802 MarR family 39 102 8.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_24165 918b481a18c87b3a06477411ffe0519c 357 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 194 0.0019 T 12-10-2018 TL08_24165 918b481a18c87b3a06477411ffe0519c 357 Gene3D G3DSA:3.40.50.720 2 348 1.5E-94 T 12-10-2018 TL08_24165 918b481a18c87b3a06477411ffe0519c 357 Pfam PF01370 NAD dependent epimerase/dehydratase family 16 236 1.8E-24 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_24165 918b481a18c87b3a06477411ffe0519c 357 SUPERFAMILY SSF51735 14 345 1.95E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_24400 96f01df344fb81b414407c60c1d3920e 141 Gene3D G3DSA:3.40.140.10 4 138 1.4E-44 T 12-10-2018 TL08_24400 96f01df344fb81b414407c60c1d3920e 141 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 18 107 6.4E-11 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TL08_24400 96f01df344fb81b414407c60c1d3920e 141 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 62 102 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TL08_24400 96f01df344fb81b414407c60c1d3920e 141 SUPERFAMILY SSF53927 5 134 1.23E-37 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TL08_10870 be10c70bdb1dba302c34cfcb75f0c549 214 Gene3D G3DSA:3.90.550.10 5 205 6.1E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_10870 be10c70bdb1dba302c34cfcb75f0c549 214 Pfam PF12804 MobA-like NTP transferase domain 11 161 2.3E-24 T 12-10-2018 IPR025877 MobA-like NTP transferase TL08_10870 be10c70bdb1dba302c34cfcb75f0c549 214 SUPERFAMILY SSF53448 9 198 8.97E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_18945 92c8a4f930d9f72531deefe00543280b 357 Pfam PF00069 Protein kinase domain 16 273 1.0E-42 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_18945 92c8a4f930d9f72531deefe00543280b 357 PIRSF PIRSF000654 38 284 1.3E-19 T 12-10-2018 TL08_18945 92c8a4f930d9f72531deefe00543280b 357 SUPERFAMILY SSF56112 14 277 3.73E-57 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_18945 92c8a4f930d9f72531deefe00543280b 357 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 137 149 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TL08_18945 92c8a4f930d9f72531deefe00543280b 357 Gene3D G3DSA:1.10.510.10 7 308 2.6E-54 T 12-10-2018 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 Gene3D G3DSA:3.30.420.40 173 370 1.9E-61 T 12-10-2018 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 PIRSF PIRSF000722 36 370 3.0E-98 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 PIRSF PIRSF000722 1 46 7.7E-4 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 Pfam PF00871 Acetokinase family 4 361 6.6E-87 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 TIGRFAM TIGR00016 ackA: acetate kinase 52 366 2.2E-88 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 PRINTS PR00471 Acetate kinase family signature 275 288 2.2E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 PRINTS PR00471 Acetate kinase family signature 176 197 2.2E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 PRINTS PR00471 Acetate kinase family signature 148 161 2.2E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 PRINTS PR00471 Acetate kinase family signature 4 15 2.2E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 PRINTS PR00471 Acetate kinase family signature 349 361 2.2E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 PRINTS PR00471 Acetate kinase family signature 297 313 2.2E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 SUPERFAMILY SSF53067 132 368 4.17E-64 T 12-10-2018 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 176 193 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 Hamap MF_00020 Acetate kinase [ackA]. 1 370 117.578 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 Gene3D G3DSA:3.30.420.40 1 170 1.0E-46 T 12-10-2018 TL08_11100 737c85ee368ce61bffb3fe534347cacc 370 SUPERFAMILY SSF53067 3 169 3.45E-43 T 12-10-2018 TL08_16075 d91ffac4a34f36fe9d2d3f1b65da3985 199 Gene3D G3DSA:1.10.357.10 9 199 6.9E-48 T 12-10-2018 TL08_16075 d91ffac4a34f36fe9d2d3f1b65da3985 199 SUPERFAMILY SSF46689 14 96 1.1E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16075 d91ffac4a34f36fe9d2d3f1b65da3985 199 SUPERFAMILY SSF48498 93 196 1.67E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_16075 d91ffac4a34f36fe9d2d3f1b65da3985 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16075 d91ffac4a34f36fe9d2d3f1b65da3985 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16075 d91ffac4a34f36fe9d2d3f1b65da3985 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 5.8E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19485 243945b9a4e842e34d614b747e0bb4ec 279 SMART SM00382 47 235 5.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_19485 243945b9a4e842e34d614b747e0bb4ec 279 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_19485 243945b9a4e842e34d614b747e0bb4ec 279 SUPERFAMILY SSF52540 31 258 4.05E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19485 243945b9a4e842e34d614b747e0bb4ec 279 Gene3D G3DSA:3.40.50.300 13 277 5.5E-80 T 12-10-2018 TL08_19485 243945b9a4e842e34d614b747e0bb4ec 279 Pfam PF00005 ABC transporter 38 186 1.2E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_06845 589515f59861be4b55713f91314c0ff7 299 Pfam PF02517 CAAX protease self-immunity 137 222 5.0E-13 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 Gene3D G3DSA:2.120.10.30 124 227 4.3E-31 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 Gene3D G3DSA:2.120.10.30 72 123 3.4E-17 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 Gene3D G3DSA:2.120.10.30 11 71 4.8E-15 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 SUPERFAMILY SSF101898 39 335 1.73E-42 T 12-10-2018 TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 Gene3D G3DSA:2.40.10.500 244 342 7.4E-24 T 12-10-2018 TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 SMART SM00135 35 74 39.0 T 12-10-2018 IPR000033 LDLR class B repeat TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 SMART SM00135 299 340 55.0 T 12-10-2018 IPR000033 LDLR class B repeat TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 SMART SM00135 91 132 5.1 T 12-10-2018 IPR000033 LDLR class B repeat TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 SMART SM00135 147 188 1.6 T 12-10-2018 IPR000033 LDLR class B repeat TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 Pfam PF01436 NHL repeat 42 68 1.4E-6 T 12-10-2018 IPR001258 NHL repeat GO:0005515 TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 Pfam PF01436 NHL repeat 251 278 1.8E-8 T 12-10-2018 IPR001258 NHL repeat GO:0005515 TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 Pfam PF01436 NHL repeat 307 332 5.2E-5 T 12-10-2018 IPR001258 NHL repeat GO:0005515 TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 Pfam PF01436 NHL repeat 155 180 1.1E-7 T 12-10-2018 IPR001258 NHL repeat GO:0005515 TL08_20110 c33dc3c7b190996b632f55497ecc15ef 447 Pfam PF01436 NHL repeat 99 124 1.1E-7 T 12-10-2018 IPR001258 NHL repeat GO:0005515 TL08_14280 d1ef464742dca5173a15e9c2791d6e0f 257 Pfam PF00484 Carbonic anhydrase 104 253 1.3E-37 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TL08_14280 d1ef464742dca5173a15e9c2791d6e0f 257 SMART SM00947 96 257 4.3E-46 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TL08_14280 d1ef464742dca5173a15e9c2791d6e0f 257 SUPERFAMILY SSF53056 59 256 6.67E-52 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TL08_14280 d1ef464742dca5173a15e9c2791d6e0f 257 Gene3D G3DSA:3.40.1050.10 54 257 3.8E-66 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TL08_14280 d1ef464742dca5173a15e9c2791d6e0f 257 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 108 115 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TL08_23450 348f9874f3dc4a3ae0b7a7ed632bddc0 240 SUPERFAMILY SSF56801 7 236 2.88E-16 T 12-10-2018 TL08_23450 348f9874f3dc4a3ae0b7a7ed632bddc0 240 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 8 235 1.2E-60 T 12-10-2018 IPR017523 Conserved hypothetical protein CHP03089 TL08_23450 348f9874f3dc4a3ae0b7a7ed632bddc0 240 Gene3D G3DSA:3.40.50.12780 20 239 2.0E-8 T 12-10-2018 TL08_15370 db409d7a9e735679f15384373537107e 351 Pfam PF00494 Squalene/phytoene synthase 31 280 2.6E-38 T 12-10-2018 TL08_15370 db409d7a9e735679f15384373537107e 351 SUPERFAMILY SSF48576 18 292 3.31E-43 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_15370 db409d7a9e735679f15384373537107e 351 Gene3D G3DSA:1.10.600.10 8 270 1.5E-54 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_03460 9e52b14d344454622234788a3e5a0690 362 SUPERFAMILY SSF52540 9 149 2.87E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03460 9e52b14d344454622234788a3e5a0690 362 Pfam PF07728 AAA domain (dynein-related subfamily) 20 148 6.4E-8 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TL08_03460 9e52b14d344454622234788a3e5a0690 362 SMART SM00382 17 151 1.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_03460 9e52b14d344454622234788a3e5a0690 362 Gene3D G3DSA:3.40.50.300 2 158 6.0E-23 T 12-10-2018 TL08_24045 efb9391193b1109b4c1371562d0f41d4 144 Gene3D G3DSA:1.10.1660.10 13 144 2.2E-30 T 12-10-2018 TL08_24045 efb9391193b1109b4c1371562d0f41d4 144 Pfam PF13411 MerR HTH family regulatory protein 15 80 7.2E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24045 efb9391193b1109b4c1371562d0f41d4 144 SMART SM00422 15 84 3.3E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24045 efb9391193b1109b4c1371562d0f41d4 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 51 71 8.7E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24045 efb9391193b1109b4c1371562d0f41d4 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 27 40 8.7E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24045 efb9391193b1109b4c1371562d0f41d4 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 27 8.7E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24045 efb9391193b1109b4c1371562d0f41d4 144 SUPERFAMILY SSF46955 15 129 3.37E-29 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_24045 efb9391193b1109b4c1371562d0f41d4 144 ProSitePatterns PS00552 MerR-type HTH domain signature. 18 40 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_13520 de82da0b61810f6469ee4e1c724dd3f6 170 SUPERFAMILY SSF109854 2 160 2.59E-31 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_13520 de82da0b61810f6469ee4e1c724dd3f6 170 Gene3D G3DSA:1.20.120.450 1 162 4.7E-57 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_13520 de82da0b61810f6469ee4e1c724dd3f6 170 Pfam PF04978 Protein of unknown function (DUF664) 2 160 1.8E-16 T 12-10-2018 IPR007061 Protein of unknown function DUF664 TL08_25630 396954bedfcff36a4e33d3c3e12d03b8 552 Pfam PF13440 Polysaccharide biosynthesis protein 63 103 7.5E-5 T 12-10-2018 TL08_25630 396954bedfcff36a4e33d3c3e12d03b8 552 Pfam PF13440 Polysaccharide biosynthesis protein 133 380 3.5E-46 T 12-10-2018 TL08_08695 fcf2cde4d80cef6daaf54db7f078354b 149 SUPERFAMILY SSF46785 4 135 2.88E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_08695 fcf2cde4d80cef6daaf54db7f078354b 149 Gene3D G3DSA:1.10.10.10 2 140 1.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05905 a7a7a5ac4f477f577f4b4b421f1035ba 247 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 27 202 1.3E-15 T 12-10-2018 IPR008884 Macrocin-O-methyltransferase TL08_05905 a7a7a5ac4f477f577f4b4b421f1035ba 247 Gene3D G3DSA:3.40.50.150 2 225 5.2E-36 T 12-10-2018 TL08_01795 f5038945b9481c8a672130821be9ee0f 250 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 232 3.4E-62 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TL08_01795 f5038945b9481c8a672130821be9ee0f 250 Gene3D G3DSA:3.90.550.10 1 236 1.5E-67 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_01795 f5038945b9481c8a672130821be9ee0f 250 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 233 1.5E-61 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TL08_01795 f5038945b9481c8a672130821be9ee0f 250 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 232 37.297 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TL08_01795 f5038945b9481c8a672130821be9ee0f 250 SUPERFAMILY SSF53448 3 232 1.21E-49 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_01795 f5038945b9481c8a672130821be9ee0f 250 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 102 109 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TL08_12580 8c565075261687ad9a081d31fd21647d 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 279 3.1E-32 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_26180 296ff5f8a17589a1a02ac57c0b67aed7 356 Pfam PF13515 Fusaric acid resistance protein-like 24 146 3.0E-13 T 12-10-2018 TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 Pfam PF02080 TrkA-C domain 149 210 3.8E-7 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 SUPERFAMILY SSF51735 2 140 2.26E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 Gene3D G3DSA:3.40.50.720 1 131 1.2E-29 T 12-10-2018 TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 Gene3D G3DSA:3.30.70.1450 143 214 9.8E-7 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.9E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 4.9E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.9E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 4.9E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 Pfam PF02254 TrkA-N domain 3 117 2.7E-23 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TL08_08435 f0fedb87e12f13d83ecabb91028dbcaa 221 SUPERFAMILY SSF116726 133 210 7.06E-6 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TL08_15810 887e5452a46618ee643d2917698f1214 370 Gene3D G3DSA:1.20.140.10 226 370 3.3E-46 T 12-10-2018 TL08_15810 887e5452a46618ee643d2917698f1214 370 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 2 108 4.3E-8 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TL08_15810 887e5452a46618ee643d2917698f1214 370 Gene3D G3DSA:1.10.540.10 1 111 9.9E-11 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_15810 887e5452a46618ee643d2917698f1214 370 SUPERFAMILY SSF56645 2 219 4.84E-56 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_15810 887e5452a46618ee643d2917698f1214 370 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 116 209 3.3E-25 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TL08_15810 887e5452a46618ee643d2917698f1214 370 PIRSF PIRSF016578 123 360 6.6E-16 T 12-10-2018 TL08_15810 887e5452a46618ee643d2917698f1214 370 PIRSF PIRSF016578 1 99 44.0 T 12-10-2018 TL08_15810 887e5452a46618ee643d2917698f1214 370 Gene3D G3DSA:2.40.110.10 114 225 6.5E-35 T 12-10-2018 TL08_15810 887e5452a46618ee643d2917698f1214 370 SUPERFAMILY SSF47203 220 370 3.06E-47 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_15810 887e5452a46618ee643d2917698f1214 370 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 221 370 6.1E-40 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TL08_04840 79da4049f2a2f8d4b7d726a777ff0283 355 Gene3D G3DSA:3.40.50.720 136 276 3.1E-39 T 12-10-2018 TL08_04840 79da4049f2a2f8d4b7d726a777ff0283 355 Gene3D G3DSA:1.10.287.70 34 135 1.2E-13 T 12-10-2018 TL08_04840 79da4049f2a2f8d4b7d726a777ff0283 355 SUPERFAMILY SSF51735 139 283 1.66E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_04840 79da4049f2a2f8d4b7d726a777ff0283 355 Pfam PF07885 Ion channel 45 123 4.0E-12 T 12-10-2018 IPR013099 Potassium channel domain TL08_04840 79da4049f2a2f8d4b7d726a777ff0283 355 Pfam PF02254 TrkA-N domain 143 260 9.4E-26 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TL08_04840 79da4049f2a2f8d4b7d726a777ff0283 355 SUPERFAMILY SSF81324 38 159 1.11E-18 T 12-10-2018 TL08_13275 9ff6b1115d007e7d43808945a2374f53 204 SMART SM00641 3 111 0.0024 T 12-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup TL08_13275 9ff6b1115d007e7d43808945a2374f53 204 Pfam PF01183 Glycosyl hydrolases family 25 6 183 1.7E-28 T 12-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 TL08_13275 9ff6b1115d007e7d43808945a2374f53 204 SUPERFAMILY SSF51445 2 193 6.88E-38 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_13275 9ff6b1115d007e7d43808945a2374f53 204 Gene3D G3DSA:3.20.20.80 2 197 5.1E-40 T 12-10-2018 TL08_09505 e73a760d3e06b49160ca5bf1bfc5c598 281 SUPERFAMILY SSF47413 7 67 3.1E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_09505 e73a760d3e06b49160ca5bf1bfc5c598 281 Pfam PF13560 Helix-turn-helix domain 10 70 4.7E-10 T 12-10-2018 TL08_09505 e73a760d3e06b49160ca5bf1bfc5c598 281 Gene3D G3DSA:1.10.260.40 5 71 7.0E-9 T 12-10-2018 TL08_09505 e73a760d3e06b49160ca5bf1bfc5c598 281 SMART SM00530 14 69 0.003 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_22645 a871ac5da599f8ad355222544cb88026 200 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 38.251 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TL08_22645 a871ac5da599f8ad355222544cb88026 200 SUPERFAMILY SSF52016 1 187 4.51E-52 T 12-10-2018 TL08_22645 a871ac5da599f8ad355222544cb88026 200 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 177 1.1E-54 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TL08_22645 a871ac5da599f8ad355222544cb88026 200 Pfam PF00694 Aconitase C-terminal domain 1 115 1.1E-23 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TL08_22645 a871ac5da599f8ad355222544cb88026 200 Gene3D G3DSA:3.20.19.10 1 168 2.7E-66 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TL08_02255 c2bce79497ac4fb0e720720f706f8404 131 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_02255 c2bce79497ac4fb0e720720f706f8404 131 SUPERFAMILY SSF46955 1 111 1.79E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_02255 c2bce79497ac4fb0e720720f706f8404 131 Gene3D G3DSA:1.10.1660.10 1 122 8.2E-28 T 12-10-2018 TL08_02255 c2bce79497ac4fb0e720720f706f8404 131 SMART SM00422 1 69 1.1E-21 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_02255 c2bce79497ac4fb0e720720f706f8404 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 4.8E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_02255 c2bce79497ac4fb0e720720f706f8404 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.8E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_02255 c2bce79497ac4fb0e720720f706f8404 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.8E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_02255 c2bce79497ac4fb0e720720f706f8404 131 Pfam PF13411 MerR HTH family regulatory protein 1 67 6.6E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_13755 4fdb1970aa6a9254c73f9e10236fa312 209 Gene3D G3DSA:3.40.50.1820 5 207 1.7E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13755 4fdb1970aa6a9254c73f9e10236fa312 209 Pfam PF02230 Phospholipase/Carboxylesterase 14 205 3.2E-13 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 TL08_13755 4fdb1970aa6a9254c73f9e10236fa312 209 SUPERFAMILY SSF53474 9 205 1.91E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10850 0352fe7dca354105ade95102e77261bb 422 Pfam PF00877 NlpC/P60 family 298 419 7.6E-27 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain TL08_10850 0352fe7dca354105ade95102e77261bb 422 SUPERFAMILY SSF54001 277 411 2.6E-34 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TL08_10850 0352fe7dca354105ade95102e77261bb 422 Gene3D G3DSA:3.90.1720.10 207 422 1.2E-53 T 12-10-2018 TL08_00895 bebf8940fab30b2a4537186a617a8fa5 334 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 35 325 4.8E-102 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TL08_00895 bebf8940fab30b2a4537186a617a8fa5 334 Gene3D G3DSA:3.40.718.10 1 330 3.4E-132 T 12-10-2018 TL08_00895 bebf8940fab30b2a4537186a617a8fa5 334 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 8 329 3.2E-107 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TL08_00895 bebf8940fab30b2a4537186a617a8fa5 334 SUPERFAMILY SSF53659 6 330 1.69E-104 T 12-10-2018 TL08_26170 8422f078ebcb1efee86a30f2f4f969f8 214 Pfam PF07510 Protein of unknown function (DUF1524) 110 209 4.8E-13 T 12-10-2018 IPR011089 Domain of unknown function DUF1524 TL08_21885 ce4423bdb338915d6f5f53d10a6484e6 316 Pfam PF00296 Luciferase-like monooxygenase 8 256 2.3E-53 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_21885 ce4423bdb338915d6f5f53d10a6484e6 316 Gene3D G3DSA:3.20.20.30 8 316 5.9E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_21885 ce4423bdb338915d6f5f53d10a6484e6 316 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 7 236 2.2E-88 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c TL08_21885 ce4423bdb338915d6f5f53d10a6484e6 316 SUPERFAMILY SSF51679 6 315 1.7E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_03445 0841cdf47113b8499536ec1b13e588e8 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 56 7.0E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_03445 0841cdf47113b8499536ec1b13e588e8 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 8.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_03445 0841cdf47113b8499536ec1b13e588e8 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 8.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_03445 0841cdf47113b8499536ec1b13e588e8 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 8.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_03445 0841cdf47113b8499536ec1b13e588e8 301 Gene3D G3DSA:3.40.190.290 86 285 1.2E-43 T 12-10-2018 TL08_03445 0841cdf47113b8499536ec1b13e588e8 301 Gene3D G3DSA:1.10.10.10 1 79 1.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_03445 0841cdf47113b8499536ec1b13e588e8 301 SUPERFAMILY SSF53850 82 274 7.85E-38 T 12-10-2018 TL08_03445 0841cdf47113b8499536ec1b13e588e8 301 Pfam PF03466 LysR substrate binding domain 83 275 9.3E-42 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_03445 0841cdf47113b8499536ec1b13e588e8 301 SUPERFAMILY SSF46785 1 77 1.96E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_07215 1850a433c6ec55ad475c65096ad30e3a 215 Gene3D G3DSA:1.10.10.60 5 54 4.5E-23 T 12-10-2018 TL08_07215 1850a433c6ec55ad475c65096ad30e3a 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 1.7E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_07215 1850a433c6ec55ad475c65096ad30e3a 215 Gene3D G3DSA:1.10.357.10 56 199 1.6E-24 T 12-10-2018 TL08_07215 1850a433c6ec55ad475c65096ad30e3a 215 SUPERFAMILY SSF46689 5 79 1.94E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_12975 775bd88cd3856763447e280d9e93bb0c 605 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 18 573 1.1E-56 T 12-10-2018 IPR010144 CRISPR-associated protein, Csd1-type TL08_23715 49c40968ac5020d9eda3f345fc7f955a 365 Pfam PF08402 TOBE domain 284 359 1.3E-15 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TL08_23715 49c40968ac5020d9eda3f345fc7f955a 365 SMART SM00382 27 216 9.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23715 49c40968ac5020d9eda3f345fc7f955a 365 Gene3D G3DSA:3.40.50.300 1 242 2.4E-69 T 12-10-2018 TL08_23715 49c40968ac5020d9eda3f345fc7f955a 365 SUPERFAMILY SSF52540 3 245 1.69E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23715 49c40968ac5020d9eda3f345fc7f955a 365 SUPERFAMILY SSF50331 242 359 2.65E-12 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TL08_23715 49c40968ac5020d9eda3f345fc7f955a 365 Gene3D G3DSA:2.40.50.100 286 354 7.1E-9 T 12-10-2018 TL08_23715 49c40968ac5020d9eda3f345fc7f955a 365 Gene3D G3DSA:2.40.50.140 252 358 7.1E-9 T 12-10-2018 TL08_23715 49c40968ac5020d9eda3f345fc7f955a 365 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_23715 49c40968ac5020d9eda3f345fc7f955a 365 Pfam PF00005 ABC transporter 19 166 1.6E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05515 2974a123f43ccca87238a5667f5979ff 212 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 5 200 7.6E-25 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 TL08_18585 12b1823e6b8d62870c1bbf9184b48380 278 Gene3D G3DSA:3.90.25.10 124 258 3.4E-59 T 12-10-2018 TL08_18585 12b1823e6b8d62870c1bbf9184b48380 278 Pfam PF13460 NAD(P)H-binding 10 172 6.4E-13 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_18585 12b1823e6b8d62870c1bbf9184b48380 278 Gene3D G3DSA:3.40.50.720 7 256 3.4E-59 T 12-10-2018 TL08_18585 12b1823e6b8d62870c1bbf9184b48380 278 SUPERFAMILY SSF51735 5 267 6.67E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16560 7e99212aaee51709660c890dc1419574 205 Gene3D G3DSA:1.10.357.10 13 202 5.0E-48 T 12-10-2018 TL08_16560 7e99212aaee51709660c890dc1419574 205 SUPERFAMILY SSF46689 17 95 3.79E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16560 7e99212aaee51709660c890dc1419574 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 3.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16560 7e99212aaee51709660c890dc1419574 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 3.2E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16560 7e99212aaee51709660c890dc1419574 205 SUPERFAMILY SSF48498 96 199 1.51E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_16560 7e99212aaee51709660c890dc1419574 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 76 1.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15155 da74809178c6359d33e0a515ce31bf46 241 Gene3D G3DSA:3.40.50.880 2 220 1.2E-64 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_15155 da74809178c6359d33e0a515ce31bf46 241 Pfam PF01965 DJ-1/PfpI family 11 176 3.9E-24 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TL08_15155 da74809178c6359d33e0a515ce31bf46 241 SUPERFAMILY SSF52317 10 199 1.44E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_17110 404b182c82684f073183ca76e554d0a6 465 Gene3D G3DSA:1.10.630.10 20 412 1.5E-83 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17110 404b182c82684f073183ca76e554d0a6 465 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_17110 404b182c82684f073183ca76e554d0a6 465 SUPERFAMILY SSF48264 22 406 6.29E-58 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_17110 404b182c82684f073183ca76e554d0a6 465 PRINTS PR00359 B-class P450 signature 154 170 4.2E-5 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17110 404b182c82684f073183ca76e554d0a6 465 PRINTS PR00359 B-class P450 signature 344 353 4.2E-5 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_17110 404b182c82684f073183ca76e554d0a6 465 PRINTS PR00359 B-class P450 signature 204 226 4.2E-5 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_04055 b77dc762ea3223b0addc2f110f568cd4 293 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 287 1.3E-152 T 12-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 TL08_04055 b77dc762ea3223b0addc2f110f568cd4 293 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 154 2.6E-27 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TL08_04055 b77dc762ea3223b0addc2f110f568cd4 293 SUPERFAMILY SSF102588 4 287 3.66E-76 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_04055 b77dc762ea3223b0addc2f110f568cd4 293 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 288 53.769 T 12-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 TL08_04055 b77dc762ea3223b0addc2f110f568cd4 293 Gene3D G3DSA:3.40.50.10320 1 293 5.1E-82 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_16245 c49bc7073505d4bb0ddef10664f09c85 533 Pfam PF00135 Carboxylesterase family 44 512 1.7E-106 T 12-10-2018 IPR002018 Carboxylesterase, type B TL08_16245 c49bc7073505d4bb0ddef10664f09c85 533 Gene3D G3DSA:3.40.50.1820 40 533 6.4E-132 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16245 c49bc7073505d4bb0ddef10664f09c85 533 SUPERFAMILY SSF53474 43 495 4.42E-105 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16245 c49bc7073505d4bb0ddef10664f09c85 533 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 203 218 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site TL08_04480 b49921b64550b925c93457bd5bbeafee 361 Gene3D G3DSA:2.160.10.10 194 361 4.4E-67 T 12-10-2018 TL08_04480 b49921b64550b925c93457bd5bbeafee 361 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 95 360 1.2E-140 T 12-10-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 TL08_04480 b49921b64550b925c93457bd5bbeafee 361 SUPERFAMILY SSF51161 119 340 5.83E-37 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TL08_04480 b49921b64550b925c93457bd5bbeafee 361 Gene3D G3DSA:3.30.70.2010 6 153 8.7E-43 T 12-10-2018 TL08_04480 b49921b64550b925c93457bd5bbeafee 361 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 275 307 1.8E-14 T 12-10-2018 IPR001451 Hexapeptide repeat TL08_04480 b49921b64550b925c93457bd5bbeafee 361 Gene3D G3DSA:3.30.60.70 154 193 1.6E-22 T 12-10-2018 IPR038361 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain superfamily KEGG: 00300+2.3.1.117 TL08_04480 b49921b64550b925c93457bd5bbeafee 361 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 154 193 7.6E-19 T 12-10-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 TL08_04480 b49921b64550b925c93457bd5bbeafee 361 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 11 358 43.461 T 12-10-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 TL08_09690 61728e6441dcbc2d114e461071789a38 196 Gene3D G3DSA:1.20.120.450 20 193 3.2E-26 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_09690 61728e6441dcbc2d114e461071789a38 196 Pfam PF04978 Protein of unknown function (DUF664) 37 192 5.0E-38 T 12-10-2018 IPR007061 Protein of unknown function DUF664 TL08_09690 61728e6441dcbc2d114e461071789a38 196 SUPERFAMILY SSF109854 23 191 2.59E-33 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_19850 b98027d3e1eb114d839b5bcc91555aa5 457 SUPERFAMILY SSF51556 46 370 1.46E-45 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_19850 b98027d3e1eb114d839b5bcc91555aa5 457 SUPERFAMILY SSF51338 4 441 1.21E-23 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_19850 b98027d3e1eb114d839b5bcc91555aa5 457 Pfam PF01979 Amidohydrolase family 43 417 1.4E-22 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_19850 b98027d3e1eb114d839b5bcc91555aa5 457 Gene3D G3DSA:2.30.40.10 2 424 1.2E-88 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_19850 b98027d3e1eb114d839b5bcc91555aa5 457 Gene3D G3DSA:3.20.20.140 48 428 1.2E-88 T 12-10-2018 TL08_01430 4820f6c29c88293ab5444b6882381628 438 Gene3D G3DSA:3.40.50.12170 57 437 5.2E-129 T 12-10-2018 TL08_01430 4820f6c29c88293ab5444b6882381628 438 Pfam PF07075 Protein of unknown function (DUF1343) 74 437 1.4E-130 T 12-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 TL08_01430 4820f6c29c88293ab5444b6882381628 438 PIRSF PIRSF016719 20 438 1.2E-134 T 12-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 TL08_01430 4820f6c29c88293ab5444b6882381628 438 Gene3D G3DSA:3.90.1150.140 276 422 5.2E-129 T 12-10-2018 TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 596 607 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 Pfam PF02754 Cysteine-rich domain 725 800 0.03 T 12-10-2018 IPR004017 Cysteine-rich domain TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 SUPERFAMILY SSF55103 257 495 5.07E-50 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 Pfam PF13183 4Fe-4S dicluster domain 530 610 4.8E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 Pfam PF02913 FAD linked oxidases, C-terminal domain 256 491 1.9E-46 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 Pfam PF01565 FAD binding domain 44 180 6.0E-40 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 SUPERFAMILY SSF46548 531 615 6.8E-8 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 Gene3D G3DSA:3.30.465.40 15 263 2.6E-47 T 12-10-2018 TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 Gene3D G3DSA:3.30.70.2740 377 453 1.5E-7 T 12-10-2018 TL08_16705 994c1d7c26aaadd9ae2e6c554765bc95 959 SUPERFAMILY SSF56176 10 251 4.5E-52 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_05970 90560d43f5133cd95695502a54b81597 93 Pfam PF02583 Metal-sensitive transcriptional repressor 8 88 7.2E-31 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 TL08_05970 90560d43f5133cd95695502a54b81597 93 Gene3D G3DSA:1.20.58.1000 4 93 2.2E-34 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily TL08_15590 585b6afc27c85d8ca7c2e27170eaa5cd 274 SMART SM00382 27 211 5.5E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_15590 585b6afc27c85d8ca7c2e27170eaa5cd 274 Pfam PF00005 ABC transporter 20 167 6.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_15590 585b6afc27c85d8ca7c2e27170eaa5cd 274 Gene3D G3DSA:3.40.50.300 2 251 5.8E-68 T 12-10-2018 TL08_15590 585b6afc27c85d8ca7c2e27170eaa5cd 274 SUPERFAMILY SSF52540 3 224 2.62E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_03905 64cc8857f96b4a063b427d652f79ee23 311 SUPERFAMILY SSF161098 70 296 6.15E-64 T 12-10-2018 IPR035906 MetI-like superfamily TL08_03905 64cc8857f96b4a063b427d652f79ee23 311 Gene3D G3DSA:1.10.3720.10 66 308 9.4E-74 T 12-10-2018 IPR035906 MetI-like superfamily TL08_03905 64cc8857f96b4a063b427d652f79ee23 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 295 1.3E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_11400 74122bc291eb4087f29b5477990fe9b6 89 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 13 75 7.5E-16 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TL08_11400 74122bc291eb4087f29b5477990fe9b6 89 Gene3D G3DSA:3.30.1360.60 12 89 3.8E-25 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 TL08_11400 74122bc291eb4087f29b5477990fe9b6 89 SUPERFAMILY SSF55604 17 88 2.35E-20 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 TL08_11400 74122bc291eb4087f29b5477990fe9b6 89 Pfam PF00367 phosphotransferase system, EIIB 20 51 8.9E-13 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TL08_17985 7c3240ccbe3a55fd3105539999e9e1a9 201 Pfam PF05154 TM2 domain 137 185 1.0E-9 T 12-10-2018 IPR007829 TM2 domain TL08_17985 7c3240ccbe3a55fd3105539999e9e1a9 201 Pfam PF08044 Domain of unknown function (DUF1707) 10 62 1.6E-20 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_11620 4337c9a3c75e9cba4c05f9e96049ebc6 328 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.342 T 12-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 TL08_11620 4337c9a3c75e9cba4c05f9e96049ebc6 328 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 1.1E-103 T 12-10-2018 IPR033981 Sporulation regulator WhiA-like TL08_11620 4337c9a3c75e9cba4c05f9e96049ebc6 328 Gene3D G3DSA:3.10.28.10 2 214 4.2E-20 T 12-10-2018 IPR027434 Homing endonuclease TL08_11620 4337c9a3c75e9cba4c05f9e96049ebc6 328 Gene3D G3DSA:1.10.10.10 216 307 4.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11620 4337c9a3c75e9cba4c05f9e96049ebc6 328 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 1.1E-23 T 12-10-2018 IPR039518 WhiA, LAGLIDADG-like domain TL08_11620 4337c9a3c75e9cba4c05f9e96049ebc6 328 Pfam PF02650 WhiA C-terminal HTH domain 221 303 6.6E-19 T 12-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal TL08_11620 4337c9a3c75e9cba4c05f9e96049ebc6 328 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 2.1E-24 T 12-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain TL08_07770 b65fcbee9ddc479edf122928fc99e067 236 Gene3D G3DSA:3.40.50.720 1 201 7.0E-51 T 12-10-2018 TL08_07770 b65fcbee9ddc479edf122928fc99e067 236 SUPERFAMILY SSF51735 4 194 4.34E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_07770 b65fcbee9ddc479edf122928fc99e067 236 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 93 1.2E-16 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TL08_00820 f9dea434e268c9c0a1a8c5f03a7b6349 664 Pfam PF00041 Fibronectin type III domain 74 150 9.8E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 TL08_00820 f9dea434e268c9c0a1a8c5f03a7b6349 664 SUPERFAMILY SSF49265 66 154 7.22E-10 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 TL08_00820 f9dea434e268c9c0a1a8c5f03a7b6349 664 SMART SM00060 73 151 1.2E-5 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 TL08_00820 f9dea434e268c9c0a1a8c5f03a7b6349 664 Gene3D G3DSA:2.60.40.10 58 163 9.1E-10 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_13410 e3d53fdaf02ea34b94375f688dc0702f 376 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 206 5.7E-28 T 12-10-2018 TL08_13410 e3d53fdaf02ea34b94375f688dc0702f 376 SUPERFAMILY SSF53335 6 207 5.86E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13410 e3d53fdaf02ea34b94375f688dc0702f 376 Gene3D G3DSA:3.40.50.150 6 237 7.7E-51 T 12-10-2018 TL08_13440 306bf558c00b3378f2a34b4efee6766e 531 Pfam PF01391 Collagen triple helix repeat (20 copies) 394 445 1.9E-9 T 12-10-2018 IPR008160 Collagen triple helix repeat TL08_13440 306bf558c00b3378f2a34b4efee6766e 531 SUPERFAMILY SSF48239 163 323 2.9E-17 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TL08_13440 306bf558c00b3378f2a34b4efee6766e 531 Gene3D G3DSA:1.50.10.20 153 334 7.2E-16 T 12-10-2018 TL08_24685 19ceef912db60dd09aa5efbfdccb5279 560 SMART SM00220 12 270 4.4E-62 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_24685 19ceef912db60dd09aa5efbfdccb5279 560 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_24685 19ceef912db60dd09aa5efbfdccb5279 560 Pfam PF00069 Protein kinase domain 12 264 3.2E-48 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_24685 19ceef912db60dd09aa5efbfdccb5279 560 Gene3D G3DSA:1.10.510.10 91 272 6.2E-44 T 12-10-2018 TL08_24685 19ceef912db60dd09aa5efbfdccb5279 560 SUPERFAMILY SSF56112 5 293 6.88E-70 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_24685 19ceef912db60dd09aa5efbfdccb5279 560 Gene3D G3DSA:3.30.200.20 2 90 8.7E-25 T 12-10-2018 TL08_24685 19ceef912db60dd09aa5efbfdccb5279 560 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_23730 904f68e380835971672cf74b0f3304ef 209 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 197 2.4E-44 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 TL08_23730 904f68e380835971672cf74b0f3304ef 209 Hamap MF_00528 Septum formation protein Maf [maf]. 2 204 25.075 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 TL08_23730 904f68e380835971672cf74b0f3304ef 209 Gene3D G3DSA:3.90.950.10 1 206 4.1E-52 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TL08_23730 904f68e380835971672cf74b0f3304ef 209 Pfam PF02545 Maf-like protein 2 198 8.0E-43 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 TL08_23730 904f68e380835971672cf74b0f3304ef 209 SUPERFAMILY SSF52972 2 197 2.75E-43 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TL08_23730 904f68e380835971672cf74b0f3304ef 209 PIRSF PIRSF006305 1 206 5.5E-38 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 TL08_05595 c2278e186df6de1c826d899704d72be3 278 Pfam PF02361 Cobalt transport protein 36 229 3.0E-9 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TL08_16270 24057baf9bc5163f9583daa09d4baa91 533 Gene3D G3DSA:1.20.1220.12 412 532 1.5E-41 T 12-10-2018 TL08_16270 24057baf9bc5163f9583daa09d4baa91 533 PIRSF PIRSF001363 1 533 5.1E-230 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TL08_16270 24057baf9bc5163f9583daa09d4baa91 533 Gene3D G3DSA:3.20.20.360 2 408 3.7E-178 T 12-10-2018 TL08_16270 24057baf9bc5163f9583daa09d4baa91 533 SUPERFAMILY SSF51645 14 532 3.92E-174 T 12-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TL08_16270 24057baf9bc5163f9583daa09d4baa91 533 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 20 532 1.1E-228 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TL08_16270 24057baf9bc5163f9583daa09d4baa91 533 ProSitePatterns PS00510 Malate synthase signature. 263 278 - T 12-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TL08_16270 24057baf9bc5163f9583daa09d4baa91 533 Pfam PF01274 Malate synthase 14 532 5.4E-191 T 12-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TL08_20020 39a22e1a8dbc09f5f9a98e6907732196 382 SUPERFAMILY SSF53756 122 284 3.45E-11 T 12-10-2018 TL08_02190 d826530363449cf044b1674b6ac0b86b 270 Gene3D G3DSA:1.10.287.700 127 226 2.0E-6 T 12-10-2018 TL08_02190 d826530363449cf044b1674b6ac0b86b 270 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 71 170 2.0E-10 T 12-10-2018 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 TL08_02190 d826530363449cf044b1674b6ac0b86b 270 SUPERFAMILY SSF58113 55 193 1.23E-6 T 12-10-2018 TL08_11815 d7969d60369b6435f211041ecfeed352 111 SUPERFAMILY SSF50022 1 105 6.02E-28 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_11815 d7969d60369b6435f211041ecfeed352 111 Gene3D G3DSA:2.102.10.10 1 109 9.7E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_11815 d7969d60369b6435f211041ecfeed352 111 Pfam PF00355 Rieske [2Fe-2S] domain 4 92 1.8E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TL08_02475 21c0de13d14b5986445889062a01a23b 77 SUPERFAMILY SSF46955 15 66 8.55E-11 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_02475 21c0de13d14b5986445889062a01a23b 77 Gene3D G3DSA:1.10.1660.10 16 75 1.9E-11 T 12-10-2018 TL08_02475 21c0de13d14b5986445889062a01a23b 77 Pfam PF12728 Helix-turn-helix domain 16 63 2.4E-10 T 12-10-2018 TL08_02475 21c0de13d14b5986445889062a01a23b 77 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 16 63 8.1E-11 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TL08_10525 b1d296071349e705c9fe88601bef09cd 147 Pfam PF02699 Preprotein translocase subunit 5 80 2.6E-21 T 12-10-2018 IPR003849 Preprotein translocase YajC TL08_10525 b1d296071349e705c9fe88601bef09cd 147 SMART SM01323 1 83 2.7E-28 T 12-10-2018 IPR003849 Preprotein translocase YajC TL08_10525 b1d296071349e705c9fe88601bef09cd 147 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 83 3.5E-22 T 12-10-2018 IPR003849 Preprotein translocase YajC TL08_12055 88c4271a28bbea42cd1379fb5fe25fad 499 Pfam PF03136 Pup-ligase protein 3 454 9.2E-181 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 TL08_12055 88c4271a28bbea42cd1379fb5fe25fad 499 PIRSF PIRSF018077 8 496 1.3E-201 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 TL08_12055 88c4271a28bbea42cd1379fb5fe25fad 499 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 2 485 1.2E-228 T 12-10-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 Gene3D G3DSA:1.10.560.10 7 519 2.6E-217 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 PRINTS PR00298 60kDa chaperonin signature 266 289 3.4E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 PRINTS PR00298 60kDa chaperonin signature 348 373 3.4E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 PRINTS PR00298 60kDa chaperonin signature 396 417 3.4E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 PRINTS PR00298 60kDa chaperonin signature 26 52 3.4E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 PRINTS PR00298 60kDa chaperonin signature 82 109 3.4E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 SUPERFAMILY SSF48592 6 519 6.91E-72 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 SUPERFAMILY SSF54849 136 201 2.98E-25 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 4.3E-92 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 4.2E-246 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 Hamap MF_00600 60 kDa chaperonin [groL]. 1 537 41.003 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 Gene3D G3DSA:3.30.260.10 135 408 2.6E-217 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 Gene3D G3DSA:3.50.7.10 190 370 2.6E-217 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily TL08_25410 08d2ab12024534955e417ef6abc07d6f 539 SUPERFAMILY SSF52029 184 374 2.24E-80 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily TL08_17185 dfe9f2521c390444bf800339ed482ed2 368 Gene3D G3DSA:3.30.200.20 11 112 3.7E-8 T 12-10-2018 TL08_17185 dfe9f2521c390444bf800339ed482ed2 368 SUPERFAMILY SSF56112 17 317 2.84E-30 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_17185 dfe9f2521c390444bf800339ed482ed2 368 Gene3D G3DSA:1.20.58.840 152 349 4.5E-56 T 12-10-2018 TL08_17185 dfe9f2521c390444bf800339ed482ed2 368 Gene3D G3DSA:1.10.510.10 121 298 4.5E-56 T 12-10-2018 TL08_17185 dfe9f2521c390444bf800339ed482ed2 368 Pfam PF01636 Phosphotransferase enzyme family 76 275 2.5E-16 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_14950 163a84d157cc3511e7fd58c73c495cbf 372 Gene3D G3DSA:3.40.50.300 3 168 1.2E-17 T 12-10-2018 TL08_14950 163a84d157cc3511e7fd58c73c495cbf 372 Gene3D G3DSA:3.40.50.300 183 370 4.1E-11 T 12-10-2018 TL08_14950 163a84d157cc3511e7fd58c73c495cbf 372 SUPERFAMILY SSF52540 4 159 1.04E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14950 163a84d157cc3511e7fd58c73c495cbf 372 Pfam PF01583 Adenylylsulphate kinase 4 43 1.2E-4 T 12-10-2018 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 PRINTS PR00400 Tetracycline repressor protein signature 78 97 9.4E-12 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 PRINTS PR00400 Tetracycline repressor protein signature 26 49 9.4E-12 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 PRINTS PR00400 Tetracycline repressor protein signature 186 200 9.4E-12 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 6.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 76 202 3.4E-10 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 SUPERFAMILY SSF46689 1 68 1.4E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 Gene3D G3DSA:1.10.357.10 1 210 6.7E-59 T 12-10-2018 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_12635 a4c80d0c14f94161d2fe35c1f30d0b73 216 SUPERFAMILY SSF48498 77 204 2.33E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_02040 6f7bfd98de4ae316b8c234bedb6876ca 97 Pfam PF11662 Protein of unknown function (DUF3263) 16 88 2.7E-33 T 12-10-2018 IPR021678 Protein of unknown function DUF3263 TL08_07485 703d5eca635c6d519eb4ea9f78e21f26 119 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 3.8E-27 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane TL08_07485 703d5eca635c6d519eb4ea9f78e21f26 119 Pfam PF12823 Domain of unknown function (DUF3817) 7 94 3.2E-26 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane TL08_22375 dc76908e0a46130fb6a9ed4e334663d7 92 Pfam PF12079 Protein of unknown function (DUF3558) 17 87 1.6E-10 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 TL08_24130 babb62e5267e3c1936f928e026c5b752 230 SUPERFAMILY SSF46955 1 98 2.47E-15 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_24130 babb62e5267e3c1936f928e026c5b752 230 SMART SM00422 1 71 2.1E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24130 babb62e5267e3c1936f928e026c5b752 230 Gene3D G3DSA:1.10.1660.10 2 212 3.8E-52 T 12-10-2018 TL08_24130 babb62e5267e3c1936f928e026c5b752 230 Pfam PF13411 MerR HTH family regulatory protein 1 68 1.1E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24130 babb62e5267e3c1936f928e026c5b752 230 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.4E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24130 babb62e5267e3c1936f928e026c5b752 230 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.4E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_24130 babb62e5267e3c1936f928e026c5b752 230 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.4E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_06835 9016f106458bf52678a80d457bd910e8 310 SUPERFAMILY SSF53474 59 304 1.14E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06835 9016f106458bf52678a80d457bd910e8 310 Pfam PF00561 alpha/beta hydrolase fold 82 185 1.4E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_06835 9016f106458bf52678a80d457bd910e8 310 Gene3D G3DSA:3.40.50.1820 40 306 9.3E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06835 9016f106458bf52678a80d457bd910e8 310 PRINTS PR00111 Alpha/beta hydrolase fold signature 152 165 1.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_06835 9016f106458bf52678a80d457bd910e8 310 PRINTS PR00111 Alpha/beta hydrolase fold signature 166 179 1.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_06835 9016f106458bf52678a80d457bd910e8 310 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 122 1.4E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_18390 2cb18b0aeef6252fc3c4483e0bc187ed 336 SUPERFAMILY SSF51679 6 330 2.06E-61 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_18390 2cb18b0aeef6252fc3c4483e0bc187ed 336 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 9 330 9.9E-140 T 12-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related TL08_18390 2cb18b0aeef6252fc3c4483e0bc187ed 336 Gene3D G3DSA:3.20.20.30 6 331 1.9E-64 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_18390 2cb18b0aeef6252fc3c4483e0bc187ed 336 Pfam PF00296 Luciferase-like monooxygenase 8 302 7.2E-51 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_21275 54dd35f488f9c45c3ea68880763b5371 132 SUPERFAMILY SSF54909 3 67 1.37E-7 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_21275 54dd35f488f9c45c3ea68880763b5371 132 Gene3D G3DSA:3.30.70.100 1 99 6.3E-8 T 12-10-2018 TL08_21275 54dd35f488f9c45c3ea68880763b5371 132 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 68 2.1E-5 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TL08_01515 f5a4bd7a05c999cb922b560663759122 662 Gene3D G3DSA:3.40.50.300 445 640 1.9E-27 T 12-10-2018 TL08_01515 f5a4bd7a05c999cb922b560663759122 662 SUPERFAMILY SSF103473 3 414 1.44E-31 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_01515 f5a4bd7a05c999cb922b560663759122 662 Hamap MF_00165 Thymidylate kinase [tmk]. 448 638 14.308 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TL08_01515 f5a4bd7a05c999cb922b560663759122 662 Pfam PF07690 Major Facilitator Superfamily 12 367 1.4E-14 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_01515 f5a4bd7a05c999cb922b560663759122 662 Pfam PF02223 Thymidylate kinase 462 628 3.2E-9 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TL08_01515 f5a4bd7a05c999cb922b560663759122 662 Gene3D G3DSA:1.20.1250.20 2 420 1.2E-27 T 12-10-2018 TL08_01515 f5a4bd7a05c999cb922b560663759122 662 SUPERFAMILY SSF52540 462 637 3.31E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08180 c3feb2c3240939afceb049abf4a3e4ff 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_08180 c3feb2c3240939afceb049abf4a3e4ff 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 4.5E-26 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08180 c3feb2c3240939afceb049abf4a3e4ff 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 9.2E-35 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08180 c3feb2c3240939afceb049abf4a3e4ff 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 22.936 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_08180 c3feb2c3240939afceb049abf4a3e4ff 103 SUPERFAMILY SSF141091 1 100 1.44E-32 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_24310 f7179d6b9e8942fed1640b58c80ed988 298 Pfam PF12697 Alpha/beta hydrolase family 21 288 2.4E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_24310 f7179d6b9e8942fed1640b58c80ed988 298 Gene3D G3DSA:3.40.50.1820 16 296 2.4E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_24310 f7179d6b9e8942fed1640b58c80ed988 298 SUPERFAMILY SSF53474 16 289 3.87E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10075 579a715ccb3c382a0c323a52cc1f9f82 169 SUPERFAMILY SSF52402 12 151 3.27E-30 T 12-10-2018 TL08_10075 579a715ccb3c382a0c323a52cc1f9f82 169 PRINTS PR01438 Universal stress protein signature 109 121 1.4E-15 T 12-10-2018 IPR006015 Universal stress protein A TL08_10075 579a715ccb3c382a0c323a52cc1f9f82 169 PRINTS PR01438 Universal stress protein signature 127 149 1.4E-15 T 12-10-2018 IPR006015 Universal stress protein A TL08_10075 579a715ccb3c382a0c323a52cc1f9f82 169 PRINTS PR01438 Universal stress protein signature 11 29 1.4E-15 T 12-10-2018 IPR006015 Universal stress protein A TL08_10075 579a715ccb3c382a0c323a52cc1f9f82 169 Gene3D G3DSA:3.40.50.620 3 160 2.3E-37 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_10075 579a715ccb3c382a0c323a52cc1f9f82 169 Pfam PF00582 Universal stress protein family 12 149 1.8E-24 T 12-10-2018 IPR006016 UspA TL08_26050 76c48e0947ba0f95de1c40d5d08fe8cc 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 38.512 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_26050 76c48e0947ba0f95de1c40d5d08fe8cc 223 SMART SM01211 1 220 4.0E-118 T 12-10-2018 TL08_26050 76c48e0947ba0f95de1c40d5d08fe8cc 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 203 6.8E-33 T 12-10-2018 TL08_26050 76c48e0947ba0f95de1c40d5d08fe8cc 223 SUPERFAMILY SSF52317 1 218 7.88E-67 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_26050 76c48e0947ba0f95de1c40d5d08fe8cc 223 Gene3D G3DSA:3.40.50.880 1 221 8.4E-59 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_26050 76c48e0947ba0f95de1c40d5d08fe8cc 223 PIRSF PIRSF001586 1 223 7.3E-76 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_26050 76c48e0947ba0f95de1c40d5d08fe8cc 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 1.4E-79 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_25335 cf49b08d65ebada7e318a68c3e8b9df4 255 Gene3D G3DSA:1.10.3720.10 49 244 7.2E-21 T 12-10-2018 IPR035906 MetI-like superfamily TL08_25335 cf49b08d65ebada7e318a68c3e8b9df4 255 SUPERFAMILY SSF161098 49 239 5.36E-26 T 12-10-2018 IPR035906 MetI-like superfamily TL08_25335 cf49b08d65ebada7e318a68c3e8b9df4 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 235 9.9E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_09095 61fb98131679b63b90da9b948b771e9e 483 SUPERFAMILY SSF53790 2 237 2.09E-49 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TL08_09095 61fb98131679b63b90da9b948b771e9e 483 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TL08_09095 61fb98131679b63b90da9b948b771e9e 483 Gene3D G3DSA:3.40.1010.10 2 114 4.8E-20 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TL08_09095 61fb98131679b63b90da9b948b771e9e 483 Gene3D G3DSA:3.30.950.10 115 235 6.3E-35 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TL08_09095 61fb98131679b63b90da9b948b771e9e 483 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 213 1.9E-34 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TL08_09435 d76f9daf7b9afe4d0e2b4a00929a1302 359 SUPERFAMILY SSF52540 39 308 1.88E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09435 d76f9daf7b9afe4d0e2b4a00929a1302 359 Gene3D G3DSA:1.10.8.300 225 333 7.4E-30 T 12-10-2018 TL08_09435 d76f9daf7b9afe4d0e2b4a00929a1302 359 Gene3D G3DSA:3.40.50.300 45 210 1.3E-42 T 12-10-2018 TL08_09435 d76f9daf7b9afe4d0e2b4a00929a1302 359 PIRSF PIRSF002849 9 338 8.4E-127 T 12-10-2018 TL08_09435 d76f9daf7b9afe4d0e2b4a00929a1302 359 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 64 193 2.9E-62 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TL08_22215 37a1d55a853cb7dd7db595a6bd76975c 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 235 325 1.0E-27 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TL08_22215 37a1d55a853cb7dd7db595a6bd76975c 328 SUPERFAMILY SSF53901 14 326 1.65E-59 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_22215 37a1d55a853cb7dd7db595a6bd76975c 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 16 325 2.6E-95 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TL08_22215 37a1d55a853cb7dd7db595a6bd76975c 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 120 196 4.6E-27 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TL08_22215 37a1d55a853cb7dd7db595a6bd76975c 328 Gene3D G3DSA:3.40.47.10 7 181 8.5E-61 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_22215 37a1d55a853cb7dd7db595a6bd76975c 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 15 327 57.31 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TL08_22215 37a1d55a853cb7dd7db595a6bd76975c 328 Gene3D G3DSA:3.40.47.10 182 328 1.2E-40 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_07205 e080bc36d7b8d297e2c4bb311b5a44de 318 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 29 307 3.0E-73 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TL08_07205 e080bc36d7b8d297e2c4bb311b5a44de 318 SUPERFAMILY SSF161111 26 229 3.14E-45 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TL08_07205 e080bc36d7b8d297e2c4bb311b5a44de 318 Pfam PF01545 Cation efflux family 35 228 2.1E-36 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TL08_07205 e080bc36d7b8d297e2c4bb311b5a44de 318 Gene3D G3DSA:1.20.1510.10 29 228 8.2E-34 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TL08_07205 e080bc36d7b8d297e2c4bb311b5a44de 318 SUPERFAMILY SSF160240 233 305 3.66E-9 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TL08_12795 c8bde123463db394fe23aa9251ad1e89 191 SUPERFAMILY SSF52218 1 158 3.11E-21 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_12795 c8bde123463db394fe23aa9251ad1e89 191 Pfam PF03358 NADPH-dependent FMN reductase 6 149 5.7E-23 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TL08_12795 c8bde123463db394fe23aa9251ad1e89 191 Gene3D G3DSA:3.40.50.360 1 172 1.9E-31 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_03035 56d68dcd2bbdec1a733e6abfdc4bd86e 122 SMART SM01374 1 122 4.4E-85 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TL08_03035 56d68dcd2bbdec1a733e6abfdc4bd86e 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03035 56d68dcd2bbdec1a733e6abfdc4bd86e 122 Gene3D G3DSA:2.40.150.20 1 122 3.1E-52 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TL08_03035 56d68dcd2bbdec1a733e6abfdc4bd86e 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.2E-56 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 TL08_03035 56d68dcd2bbdec1a733e6abfdc4bd86e 122 SUPERFAMILY SSF50193 2 122 1.09E-49 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TL08_03035 56d68dcd2bbdec1a733e6abfdc4bd86e 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 2.1E-53 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TL08_03035 56d68dcd2bbdec1a733e6abfdc4bd86e 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.837 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 10 160 7.6E-39 T 12-10-2018 IPR023635 Peptide deformylase TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 SUPERFAMILY SSF56420 1 161 3.27E-54 T 12-10-2018 IPR036821 Peptide deformylase superfamily TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 Gene3D G3DSA:3.90.45.10 1 190 4.2E-64 T 12-10-2018 IPR036821 Peptide deformylase superfamily TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 PRINTS PR01576 Peptide deformylase signature 128 157 4.0E-32 T 12-10-2018 IPR023635 Peptide deformylase TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 PRINTS PR01576 Peptide deformylase signature 33 62 4.0E-32 T 12-10-2018 IPR023635 Peptide deformylase TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 PRINTS PR01576 Peptide deformylase signature 97 108 4.0E-32 T 12-10-2018 IPR023635 Peptide deformylase TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 PRINTS PR01576 Peptide deformylase signature 109 127 4.0E-32 T 12-10-2018 IPR023635 Peptide deformylase TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 PIRSF PIRSF004749 1 176 3.2E-43 T 12-10-2018 IPR023635 Peptide deformylase TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 Hamap MF_00163 Peptide deformylase [def]. 2 170 28.419 T 12-10-2018 IPR023635 Peptide deformylase TL08_02045 e503390eb3d8390ffee4d563310c4f9d 193 Pfam PF01327 Polypeptide deformylase 4 158 2.3E-43 T 12-10-2018 IPR023635 Peptide deformylase TL08_17825 5a203255f8e7077b6f34d305b9dc1edd 804 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 592 599 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TL08_17825 5a203255f8e7077b6f34d305b9dc1edd 804 SUPERFAMILY SSF53056 540 796 2.09E-48 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TL08_17825 5a203255f8e7077b6f34d305b9dc1edd 804 Gene3D G3DSA:3.40.1050.10 543 702 9.5E-46 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TL08_17825 5a203255f8e7077b6f34d305b9dc1edd 804 Gene3D G3DSA:3.40.1050.10 703 798 1.0E-10 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TL08_17825 5a203255f8e7077b6f34d305b9dc1edd 804 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 636 656 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TL08_17825 5a203255f8e7077b6f34d305b9dc1edd 804 SMART SM00947 580 788 2.4E-49 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TL08_17825 5a203255f8e7077b6f34d305b9dc1edd 804 Pfam PF00484 Carbonic anhydrase 588 783 4.7E-43 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TL08_17825 5a203255f8e7077b6f34d305b9dc1edd 804 Pfam PF00916 Sulfate permease family 34 382 4.5E-70 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 TL08_22330 d465e413bb23466f2e28b1b6c4f5a413 109 SUPERFAMILY SSF54975 21 107 3.27E-23 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TL08_22330 d465e413bb23466f2e28b1b6c4f5a413 109 Pfam PF00708 Acylphosphatase 25 106 4.5E-21 T 12-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TL08_22330 d465e413bb23466f2e28b1b6c4f5a413 109 ProSitePatterns PS00150 Acylphosphatase signature 1. 28 38 - T 12-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TL08_22330 d465e413bb23466f2e28b1b6c4f5a413 109 Gene3D G3DSA:3.30.70.100 20 108 1.6E-23 T 12-10-2018 TL08_03280 c5a7550d392b239551410069a24e5af1 197 Gene3D G3DSA:3.40.630.30 4 181 1.6E-39 T 12-10-2018 TL08_03280 c5a7550d392b239551410069a24e5af1 197 Pfam PF13302 Acetyltransferase (GNAT) domain 8 152 9.0E-15 T 12-10-2018 IPR000182 GNAT domain TL08_03280 c5a7550d392b239551410069a24e5af1 197 SUPERFAMILY SSF55729 6 175 5.04E-37 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_20750 ce2bb03a0c0a356a06e38a7d7dbc8835 341 Pfam PF13377 Periplasmic binding protein-like domain 172 334 1.8E-32 T 12-10-2018 TL08_20750 ce2bb03a0c0a356a06e38a7d7dbc8835 341 SUPERFAMILY SSF47413 5 60 1.31E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_20750 ce2bb03a0c0a356a06e38a7d7dbc8835 341 Gene3D G3DSA:3.40.50.2300 162 293 9.9E-75 T 12-10-2018 TL08_20750 ce2bb03a0c0a356a06e38a7d7dbc8835 341 Gene3D G3DSA:3.40.50.2300 65 308 9.9E-75 T 12-10-2018 TL08_20750 ce2bb03a0c0a356a06e38a7d7dbc8835 341 SMART SM00354 4 74 1.2E-23 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_20750 ce2bb03a0c0a356a06e38a7d7dbc8835 341 SUPERFAMILY SSF53822 63 336 1.12E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_20750 ce2bb03a0c0a356a06e38a7d7dbc8835 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 1.7E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_20750 ce2bb03a0c0a356a06e38a7d7dbc8835 341 Gene3D G3DSA:1.10.260.40 2 61 5.6E-18 T 12-10-2018 TL08_20750 ce2bb03a0c0a356a06e38a7d7dbc8835 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 12-10-2018 TL08_11960 70f91b255d3fa8f2fb23d6f8019df34d 269 SUPERFAMILY SSF53335 8 217 3.5E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_11960 70f91b255d3fa8f2fb23d6f8019df34d 269 Gene3D G3DSA:3.40.50.150 4 256 6.5E-38 T 12-10-2018 TL08_11960 70f91b255d3fa8f2fb23d6f8019df34d 269 Pfam PF13847 Methyltransferase domain 39 164 3.2E-24 T 12-10-2018 IPR025714 Methyltransferase domain TL08_25355 eb1174186e52d38ae20e4b2e57974a13 135 SUPERFAMILY SSF54909 24 108 2.63E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_25355 eb1174186e52d38ae20e4b2e57974a13 135 Gene3D G3DSA:3.30.70.1060 1 132 1.6E-20 T 12-10-2018 TL08_25355 eb1174186e52d38ae20e4b2e57974a13 135 Pfam PF03795 YCII-related domain 1 117 1.1E-7 T 12-10-2018 IPR005545 YCII-related TL08_04435 94e76d9e803d1c486538d0a7ce6fe7b6 331 Gene3D G3DSA:1.10.3720.10 88 322 8.5E-21 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04435 94e76d9e803d1c486538d0a7ce6fe7b6 331 SUPERFAMILY SSF161098 93 317 2.22E-17 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04435 94e76d9e803d1c486538d0a7ce6fe7b6 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 329 8.0E-40 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_13215 b876bfcca0b60014de90e2449e1683f9 280 Gene3D G3DSA:3.40.50.1000 58 240 1.9E-47 T 12-10-2018 IPR023214 HAD superfamily TL08_13215 b876bfcca0b60014de90e2449e1683f9 280 Pfam PF13419 Haloacid dehalogenase-like hydrolase 58 239 2.7E-27 T 12-10-2018 TL08_13215 b876bfcca0b60014de90e2449e1683f9 280 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 55 66 1.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_13215 b876bfcca0b60014de90e2449e1683f9 280 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 183 199 1.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_13215 b876bfcca0b60014de90e2449e1683f9 280 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 201 221 1.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_13215 b876bfcca0b60014de90e2449e1683f9 280 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 166 1.9E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_13215 b876bfcca0b60014de90e2449e1683f9 280 Gene3D G3DSA:1.10.150.240 68 140 1.9E-47 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TL08_13215 b876bfcca0b60014de90e2449e1683f9 280 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 134 237 3.5E-15 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_13215 b876bfcca0b60014de90e2449e1683f9 280 SUPERFAMILY SSF56784 56 242 5.56E-47 T 12-10-2018 IPR036412 HAD-like superfamily TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 257 5.0E-55 T 12-10-2018 TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 Gene3D G3DSA:3.40.50.720 12 259 2.8E-72 T 12-10-2018 TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 2.5E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.5E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 2.5E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 2.5E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 2.5E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 2.5E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 2.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 2.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 2.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 197 0.0036 T 12-10-2018 TL08_12550 b0488a62a606192336a2ea8cb80937c7 259 SUPERFAMILY SSF51735 17 258 1.31E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_22050 76892b9fea9ce31f201fa170fecedde6 975 Gene3D G3DSA:3.40.50.300 659 851 1.7E-7 T 12-10-2018 TL08_22050 76892b9fea9ce31f201fa170fecedde6 975 SUPERFAMILY SSF52540 476 837 8.5E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_22050 76892b9fea9ce31f201fa170fecedde6 975 Pfam PF12846 AAA-like domain 622 887 4.5E-19 T 12-10-2018 TL08_14220 c9acf0c3abbc9375f29d4589fdea7433 377 Gene3D G3DSA:3.40.710.10 5 341 1.5E-61 T 12-10-2018 TL08_14220 c9acf0c3abbc9375f29d4589fdea7433 377 SUPERFAMILY SSF56601 6 335 3.76E-54 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_14220 c9acf0c3abbc9375f29d4589fdea7433 377 Pfam PF00144 Beta-lactamase 29 332 1.1E-42 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_14285 fedcd1289ae743046d7b6440fc212999 320 SUPERFAMILY SSF101898 144 319 8.63E-16 T 12-10-2018 TL08_14285 fedcd1289ae743046d7b6440fc212999 320 Gene3D G3DSA:2.130.10.10 53 317 6.5E-10 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_26705 5c5d34339794b60456fa08940026c8c6 279 Gene3D G3DSA:3.40.50.720 1 276 2.9E-57 T 12-10-2018 TL08_26705 5c5d34339794b60456fa08940026c8c6 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 5.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26705 5c5d34339794b60456fa08940026c8c6 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 5.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26705 5c5d34339794b60456fa08940026c8c6 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 5.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26705 5c5d34339794b60456fa08940026c8c6 279 SUPERFAMILY SSF51735 2 234 2.91E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_26705 5c5d34339794b60456fa08940026c8c6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 4.0E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26705 5c5d34339794b60456fa08940026c8c6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.0E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26705 5c5d34339794b60456fa08940026c8c6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.0E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26705 5c5d34339794b60456fa08940026c8c6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 4.0E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26705 5c5d34339794b60456fa08940026c8c6 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.0E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26705 5c5d34339794b60456fa08940026c8c6 279 Pfam PF00106 short chain dehydrogenase 7 211 4.4E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_01395 811a2008e8f2b945d3512e18c73f1641 312 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 10 304 35.515 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 TL08_01395 811a2008e8f2b945d3512e18c73f1641 312 SUPERFAMILY SSF53697 16 257 2.11E-61 T 12-10-2018 TL08_01395 811a2008e8f2b945d3512e18c73f1641 312 Gene3D G3DSA:1.10.8.1080 228 305 3.6E-21 T 12-10-2018 TL08_01395 811a2008e8f2b945d3512e18c73f1641 312 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 16 304 6.3E-95 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 TL08_01395 811a2008e8f2b945d3512e18c73f1641 312 Gene3D G3DSA:3.40.50.10490 12 227 2.9E-70 T 12-10-2018 TL08_01395 811a2008e8f2b945d3512e18c73f1641 312 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 194 211 - T 12-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 TL08_16820 a3487b27645a8a60b664fa9ca1d9de25 418 SUPERFAMILY SSF56601 61 374 4.19E-75 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_16820 a3487b27645a8a60b664fa9ca1d9de25 418 Pfam PF00144 Beta-lactamase 62 373 6.1E-56 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_16820 a3487b27645a8a60b664fa9ca1d9de25 418 Gene3D G3DSA:3.40.710.10 52 385 2.1E-99 T 12-10-2018 TL08_03620 2619d7029292220032317dd23fa832dd 399 Gene3D G3DSA:3.50.50.100 1 372 8.2E-69 T 12-10-2018 TL08_03620 2619d7029292220032317dd23fa832dd 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 2.6E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_03620 2619d7029292220032317dd23fa832dd 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 2.6E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_03620 2619d7029292220032317dd23fa832dd 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 2.6E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_03620 2619d7029292220032317dd23fa832dd 399 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 265 283 2.6E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_03620 2619d7029292220032317dd23fa832dd 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.2E-10 T 12-10-2018 TL08_03620 2619d7029292220032317dd23fa832dd 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.2E-10 T 12-10-2018 TL08_03620 2619d7029292220032317dd23fa832dd 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 3.2E-10 T 12-10-2018 TL08_03620 2619d7029292220032317dd23fa832dd 399 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 3.2E-10 T 12-10-2018 TL08_03620 2619d7029292220032317dd23fa832dd 399 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 294 6.5E-37 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_03620 2619d7029292220032317dd23fa832dd 399 SUPERFAMILY SSF51905 2 301 1.6E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_22975 c0628fce6e7e9177e4deb3e6e41aa2cf 532 Pfam PF13556 PucR C-terminal helix-turn-helix domain 460 516 5.1E-16 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain TL08_22975 c0628fce6e7e9177e4deb3e6e41aa2cf 532 Gene3D G3DSA:1.10.10.2840 390 522 1.7E-18 T 12-10-2018 TL08_07505 04691f2e4e3980780d4c16864c9515e9 331 Gene3D G3DSA:1.25.40.10 253 331 2.2E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_07505 04691f2e4e3980780d4c16864c9515e9 331 Pfam PF00085 Thioredoxin 64 166 9.5E-17 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 TL08_07505 04691f2e4e3980780d4c16864c9515e9 331 Gene3D G3DSA:3.40.30.10 62 172 6.1E-23 T 12-10-2018 TL08_07505 04691f2e4e3980780d4c16864c9515e9 331 SUPERFAMILY SSF52833 61 169 1.28E-26 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_07505 04691f2e4e3980780d4c16864c9515e9 331 Pfam PF14561 Tetratricopeptide repeat 254 331 6.4E-19 T 12-10-2018 TL08_19460 99f3eb1e3e2ad879a4f39b67c40ace0e 169 ProSitePatterns PS00893 Nudix box signature. 57 78 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_19460 99f3eb1e3e2ad879a4f39b67c40ace0e 169 Pfam PF00293 NUDIX domain 17 161 7.3E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_19460 99f3eb1e3e2ad879a4f39b67c40ace0e 169 SUPERFAMILY SSF55811 14 164 7.31E-20 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_19460 99f3eb1e3e2ad879a4f39b67c40ace0e 169 Gene3D G3DSA:3.90.79.10 16 166 1.4E-20 T 12-10-2018 TL08_15275 2b9449f112e8625a45c92deb2c4e20d4 271 Pfam PF00156 Phosphoribosyl transferase domain 67 254 1.1E-22 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TL08_15275 2b9449f112e8625a45c92deb2c4e20d4 271 Gene3D G3DSA:3.40.50.2020 63 263 1.5E-65 T 12-10-2018 TL08_15275 2b9449f112e8625a45c92deb2c4e20d4 271 SUPERFAMILY SSF53271 62 267 9.33E-42 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_15275 2b9449f112e8625a45c92deb2c4e20d4 271 Gene3D G3DSA:3.30.1310.20 113 175 1.5E-65 T 12-10-2018 TL08_25890 8b48e9a5251287b1309b77e53dae263c 304 Gene3D G3DSA:1.10.3720.10 83 303 1.2E-31 T 12-10-2018 IPR035906 MetI-like superfamily TL08_25890 8b48e9a5251287b1309b77e53dae263c 304 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 31 297 5.8E-78 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 TL08_25890 8b48e9a5251287b1309b77e53dae263c 304 SUPERFAMILY SSF161098 35 291 1.24E-38 T 12-10-2018 IPR035906 MetI-like superfamily TL08_25890 8b48e9a5251287b1309b77e53dae263c 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 299 6.6E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 SUPERFAMILY SSF51306 82 274 3.61E-43 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 222 241 2.0E-18 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 171 183 2.0E-18 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 83 99 2.0E-18 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 Pfam PF00717 Peptidase S24-like 90 136 2.9E-6 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 70 267 2.3E-36 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 Gene3D G3DSA:2.10.109.10 79 203 3.1E-13 T 12-10-2018 TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 Gene3D G3DSA:2.10.109.10 213 280 3.2E-12 T 12-10-2018 TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 ProSitePatterns PS00761 Signal peptidases I signature 3. 227 240 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 TL08_08785 d7e8f04c2b449cc5fecd7bf439c8fc46 320 Pfam PF10502 Signal peptidase, peptidase S26 170 265 4.1E-7 T 12-10-2018 IPR019533 Peptidase S26 TL08_24745 201112c54cae9afbf3474da9164f3545 470 Pfam PF00171 Aldehyde dehydrogenase family 20 433 1.9E-87 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_24745 201112c54cae9afbf3474da9164f3545 470 SUPERFAMILY SSF53720 7 433 1.31E-86 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_24745 201112c54cae9afbf3474da9164f3545 470 Gene3D G3DSA:3.40.309.10 249 425 1.5E-90 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_24745 201112c54cae9afbf3474da9164f3545 470 Gene3D G3DSA:3.40.605.10 21 248 1.5E-90 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_18405 4a95a10cfa58990901dd0e48b255786f 173 Pfam PF05145 Transition state regulatory protein AbrB 3 159 3.5E-25 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 TL08_18405 4a95a10cfa58990901dd0e48b255786f 173 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 4 159 2.7E-30 T 12-10-2018 IPR017516 AbrB duplication TL08_04265 2edd4a812e05999d89bb9bc28360f0f1 161 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 96 7.5E-18 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TL08_04265 2edd4a812e05999d89bb9bc28360f0f1 161 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 78 3.5E-17 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TL08_04265 2edd4a812e05999d89bb9bc28360f0f1 161 SUPERFAMILY SSF69118 18 147 6.2E-38 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TL08_04265 2edd4a812e05999d89bb9bc28360f0f1 161 Gene3D G3DSA:1.20.1290.10 1 147 1.1E-42 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TL08_25360 6cc2c4d9f8e6f9e95dd4d5d881dcd84f 379 SMART SM00854 48 296 1.2E-78 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA TL08_25360 6cc2c4d9f8e6f9e95dd4d5d881dcd84f 379 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 49 294 4.5E-64 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA TL08_25360 6cc2c4d9f8e6f9e95dd4d5d881dcd84f 379 SUPERFAMILY SSF56300 48 314 8.54E-37 T 12-10-2018 TL08_25360 6cc2c4d9f8e6f9e95dd4d5d881dcd84f 379 Gene3D G3DSA:3.60.21.10 113 297 1.1E-12 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_08335 dff45163ccb0b900ca788a2049f61937 307 Gene3D G3DSA:3.40.1790.10 1 306 9.5E-114 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TL08_08335 dff45163ccb0b900ca788a2049f61937 307 SUPERFAMILY SSF110581 5 303 3.53E-95 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TL08_08335 dff45163ccb0b900ca788a2049f61937 307 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 10 305 37.599 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TL08_08335 dff45163ccb0b900ca788a2049f61937 307 Pfam PF04227 Indigoidine synthase A like protein 11 302 1.6E-112 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TL08_09005 45c889eca007817c2244c810650238ef 442 Gene3D G3DSA:1.20.1250.20 255 438 1.1E-14 T 12-10-2018 TL08_09005 45c889eca007817c2244c810650238ef 442 Gene3D G3DSA:1.20.1250.20 49 244 2.3E-13 T 12-10-2018 TL08_09005 45c889eca007817c2244c810650238ef 442 SUPERFAMILY SSF103473 62 438 1.28E-40 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_09005 45c889eca007817c2244c810650238ef 442 Pfam PF07690 Major Facilitator Superfamily 80 399 1.7E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_13090 c20dfd97dc1bf43fe315a8d3e26fb38a 363 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 100 114 2.6E-5 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TL08_13090 c20dfd97dc1bf43fe315a8d3e26fb38a 363 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 146 159 2.6E-5 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TL08_13090 c20dfd97dc1bf43fe315a8d3e26fb38a 363 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 161 1.6E-45 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TL08_13090 c20dfd97dc1bf43fe315a8d3e26fb38a 363 Pfam PF00145 C-5 cytosine-specific DNA methylase 306 358 7.6E-7 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TL08_13090 c20dfd97dc1bf43fe315a8d3e26fb38a 363 SUPERFAMILY SSF53335 2 360 7.36E-77 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13090 c20dfd97dc1bf43fe315a8d3e26fb38a 363 Gene3D G3DSA:3.90.120.10 250 351 1.1E-17 T 12-10-2018 TL08_13090 c20dfd97dc1bf43fe315a8d3e26fb38a 363 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 62 74 - T 12-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 TL08_13090 c20dfd97dc1bf43fe315a8d3e26fb38a 363 Gene3D G3DSA:3.40.50.150 1 180 2.9E-56 T 12-10-2018 TL08_13090 c20dfd97dc1bf43fe315a8d3e26fb38a 363 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 1 160 5.6E-44 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 TL08_19980 dfda1a7713d8e58e59823c4414c60466 906 Pfam PF08376 Nitrate and nitrite sensing 64 297 7.1E-25 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein TL08_19980 dfda1a7713d8e58e59823c4414c60466 906 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 526 625 1.2E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_19980 dfda1a7713d8e58e59823c4414c60466 906 Gene3D G3DSA:3.30.565.10 489 641 1.3E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_19980 dfda1a7713d8e58e59823c4414c60466 906 SMART SM00387 523 636 1.2E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_19980 dfda1a7713d8e58e59823c4414c60466 906 SUPERFAMILY SSF55874 516 636 2.36E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_00300 c131d495bd51b05a2d106c8c610619b4 434 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 148 360 2.6E-19 T 12-10-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain TL08_04525 3d7117c56bae8997cd11dd7806e99f9f 128 Gene3D G3DSA:1.10.10.10 16 120 8.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04525 3d7117c56bae8997cd11dd7806e99f9f 128 Pfam PF03551 Transcriptional regulator PadR-like family 30 102 6.8E-21 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal TL08_04525 3d7117c56bae8997cd11dd7806e99f9f 128 SUPERFAMILY SSF46785 19 121 3.96E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_08410 75791a60aa84fb81b10eb5b168beba18 167 SUPERFAMILY SSF51283 4 148 2.36E-42 T 12-10-2018 IPR036157 dUTPase-like superfamily TL08_08410 75791a60aa84fb81b10eb5b168beba18 167 Pfam PF00692 dUTPase 16 148 7.9E-28 T 12-10-2018 IPR029054 dUTPase-like TL08_08410 75791a60aa84fb81b10eb5b168beba18 167 TIGRFAM TIGR00576 dut: dUTP diphosphatase 7 148 1.1E-46 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 TL08_08410 75791a60aa84fb81b10eb5b168beba18 167 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 4 149 29.882 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 TL08_08410 75791a60aa84fb81b10eb5b168beba18 167 Gene3D G3DSA:2.70.40.10 2 152 8.8E-49 T 12-10-2018 IPR036157 dUTPase-like superfamily TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 PIRSF PIRSF000126 1 266 4.0E-68 T 12-10-2018 TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.9E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.9E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.9E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 Gene3D G3DSA:3.40.50.720 4 251 8.9E-57 T 12-10-2018 TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 Pfam PF00106 short chain dehydrogenase 10 196 3.4E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06280 ca6c6464c832cfcd679f45f38ce84c8b 266 SUPERFAMILY SSF51735 8 238 3.82E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 SUPERFAMILY SSF54368 5 103 4.32E-32 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 2.9E-26 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 SMART SM01230 104 383 5.8E-152 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 390 402 - T 12-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 473 1.7E-204 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 Gene3D G3DSA:3.30.590.10 107 462 9.0E-150 T 12-10-2018 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 2.0E-135 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 SUPERFAMILY SSF55931 105 473 1.77E-139 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TL08_21915 1baf8bb0da86e914a1e422091e7a19cc 474 Gene3D G3DSA:3.10.20.70 4 106 4.8E-39 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 3 860 0.0 T 12-10-2018 IPR024028 Polynucleotide kinase-phosphatase, bacterial TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 Pfam PF13671 AAA domain 11 137 1.4E-20 T 12-10-2018 TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 SUPERFAMILY SSF52540 11 142 5.55E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 Pfam PF00149 Calcineurin-like phosphoesterase 182 384 2.7E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 Gene3D G3DSA:3.60.21.10 172 424 3.6E-69 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 Gene3D G3DSA:3.30.470.30 636 860 4.1E-74 T 12-10-2018 TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 475 797 4.7E-144 T 12-10-2018 IPR032380 Polynucleotide kinase-phosphatase, ligase domain TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 Gene3D G3DSA:3.30.470.30 445 635 6.5E-71 T 12-10-2018 TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 SUPERFAMILY SSF56300 180 406 1.1E-39 T 12-10-2018 TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 SUPERFAMILY SSF56091 523 767 7.19E-12 T 12-10-2018 TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 801 860 7.8E-30 T 12-10-2018 IPR032390 Polynucleotide kinase-phosphatase, C-terminal TL08_04070 dded5c22824d151358d5ca31ea2d24a7 860 Gene3D G3DSA:3.40.50.300 2 171 1.1E-43 T 12-10-2018 TL08_14840 1fc8018c6ce3401b49435fe29a304dac 181 PRINTS PR00502 NUDIX hydrolase family signature 44 58 4.4E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_14840 1fc8018c6ce3401b49435fe29a304dac 181 PRINTS PR00502 NUDIX hydrolase family signature 58 73 4.4E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_14840 1fc8018c6ce3401b49435fe29a304dac 181 Pfam PF00293 NUDIX domain 15 142 5.1E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_14840 1fc8018c6ce3401b49435fe29a304dac 181 Gene3D G3DSA:3.90.79.10 12 148 5.7E-36 T 12-10-2018 TL08_14840 1fc8018c6ce3401b49435fe29a304dac 181 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_14840 1fc8018c6ce3401b49435fe29a304dac 181 SUPERFAMILY SSF55811 13 144 2.03E-26 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_24525 987608b1d9fb5adc7a7470f8019f169f 338 Pfam PF04657 Putative inner membrane exporter, YdcZ 196 329 5.1E-18 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ TL08_24525 987608b1d9fb5adc7a7470f8019f169f 338 Pfam PF04657 Putative inner membrane exporter, YdcZ 31 179 2.0E-26 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ TL08_19045 3ecc3435ce2a2100b65716c19b96a06b 1080 Pfam PF01935 Domain of unknown function DUF87 674 914 9.5E-9 T 12-10-2018 IPR002789 Helicase HerA, central domain TL08_19045 3ecc3435ce2a2100b65716c19b96a06b 1080 SUPERFAMILY SSF52540 56 384 4.14E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19045 3ecc3435ce2a2100b65716c19b96a06b 1080 SMART SM00382 56 324 0.47 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_19045 3ecc3435ce2a2100b65716c19b96a06b 1080 SMART SM00382 686 1006 1.2E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_19045 3ecc3435ce2a2100b65716c19b96a06b 1080 Gene3D G3DSA:3.40.50.300 658 767 5.3E-10 T 12-10-2018 TL08_19045 3ecc3435ce2a2100b65716c19b96a06b 1080 Gene3D G3DSA:3.40.50.300 888 1050 3.6E-16 T 12-10-2018 TL08_19045 3ecc3435ce2a2100b65716c19b96a06b 1080 SUPERFAMILY SSF52540 640 1042 1.28E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_22180 f3e6b3f1176f3c87a269f23ad637c87d 130 Gene3D G3DSA:1.10.357.10 3 122 6.9E-17 T 12-10-2018 TL08_22180 f3e6b3f1176f3c87a269f23ad637c87d 130 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 24 122 2.9E-18 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal TL08_22180 f3e6b3f1176f3c87a269f23ad637c87d 130 SUPERFAMILY SSF48498 30 117 5.29E-16 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_17940 168067fda5c50e369b8903af41de53f8 175 Gene3D G3DSA:1.10.10.10 84 161 4.3E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17940 168067fda5c50e369b8903af41de53f8 175 Pfam PF12840 Helix-turn-helix domain 91 149 4.9E-10 T 12-10-2018 TL08_17940 168067fda5c50e369b8903af41de53f8 175 SUPERFAMILY SSF46785 85 151 1.28E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23800 57953af286cab01e5009341ebf279894 292 Gene3D G3DSA:1.10.260.40 4 73 9.7E-12 T 12-10-2018 TL08_23800 57953af286cab01e5009341ebf279894 292 Pfam PF13560 Helix-turn-helix domain 14 75 3.2E-12 T 12-10-2018 TL08_23800 57953af286cab01e5009341ebf279894 292 SMART SM00530 18 72 4.0E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_23800 57953af286cab01e5009341ebf279894 292 SUPERFAMILY SSF47413 11 70 2.76E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_14240 e8be107b6037831addb13a0a3d5a2d27 411 Gene3D G3DSA:1.10.150.130 48 164 3.4E-27 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_14240 e8be107b6037831addb13a0a3d5a2d27 411 SUPERFAMILY SSF56349 165 408 5.3E-30 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_14240 e8be107b6037831addb13a0a3d5a2d27 411 SUPERFAMILY SSF47823 55 162 3.34E-26 T 12-10-2018 TL08_14240 e8be107b6037831addb13a0a3d5a2d27 411 Pfam PF00589 Phage integrase family 330 398 1.8E-6 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_05435 1ec04bc00b27f4e35dbb25ba19b926e9 133 Gene3D G3DSA:2.60.120.10 5 130 1.5E-42 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_05435 1ec04bc00b27f4e35dbb25ba19b926e9 133 SUPERFAMILY SSF51182 6 131 1.78E-28 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_05435 1ec04bc00b27f4e35dbb25ba19b926e9 133 Pfam PF07883 Cupin domain 39 100 1.1E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TL08_11415 7b6d8704c9aca87b6f9569a5fd928adf 395 Hamap MF_00300 Chorismate synthase [aroC]. 2 376 33.922 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TL08_11415 7b6d8704c9aca87b6f9569a5fd928adf 395 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TL08_11415 7b6d8704c9aca87b6f9569a5fd928adf 395 PIRSF PIRSF001456 1 387 1.5E-122 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TL08_11415 7b6d8704c9aca87b6f9569a5fd928adf 395 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TL08_11415 7b6d8704c9aca87b6f9569a5fd928adf 395 TIGRFAM TIGR00033 aroC: chorismate synthase 2 374 4.5E-121 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TL08_11415 7b6d8704c9aca87b6f9569a5fd928adf 395 Pfam PF01264 Chorismate synthase 2 369 1.7E-113 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TL08_11415 7b6d8704c9aca87b6f9569a5fd928adf 395 Gene3D G3DSA:3.60.150.10 1 395 1.8E-154 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TL08_11415 7b6d8704c9aca87b6f9569a5fd928adf 395 SUPERFAMILY SSF103263 2 392 2.35E-131 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TL08_02930 8069c191f3a0ae2c0bd36117afc915c9 327 SMART SM00382 56 234 1.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_02930 8069c191f3a0ae2c0bd36117afc915c9 327 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_02930 8069c191f3a0ae2c0bd36117afc915c9 327 Gene3D G3DSA:3.40.50.300 20 255 4.2E-63 T 12-10-2018 TL08_02930 8069c191f3a0ae2c0bd36117afc915c9 327 SUPERFAMILY SSF52540 24 251 5.33E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_02930 8069c191f3a0ae2c0bd36117afc915c9 327 Pfam PF00005 ABC transporter 48 185 1.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_10435 f9b92ac332724c3c520cf384a15ef036 327 Gene3D G3DSA:1.10.1040.10 192 318 1.3E-33 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TL08_10435 f9b92ac332724c3c520cf384a15ef036 327 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 193 312 7.5E-23 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TL08_10435 f9b92ac332724c3c520cf384a15ef036 327 SUPERFAMILY SSF51735 34 191 8.37E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_10435 f9b92ac332724c3c520cf384a15ef036 327 Gene3D G3DSA:3.40.50.720 17 191 4.6E-41 T 12-10-2018 TL08_10435 f9b92ac332724c3c520cf384a15ef036 327 PIRSF PIRSF000103 26 323 1.7E-69 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TL08_10435 f9b92ac332724c3c520cf384a15ef036 327 SUPERFAMILY SSF48179 192 313 5.87E-31 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_10435 f9b92ac332724c3c520cf384a15ef036 327 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 34 190 4.3E-31 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TL08_01310 57b1be9cdfb4dc80a3de8a499bed0715 394 SUPERFAMILY SSF50494 192 374 2.66E-34 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_01310 57b1be9cdfb4dc80a3de8a499bed0715 394 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 2.5E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_01310 57b1be9cdfb4dc80a3de8a499bed0715 394 PRINTS PR00834 HtrA/DegQ protease family signature 284 308 2.5E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_01310 57b1be9cdfb4dc80a3de8a499bed0715 394 PRINTS PR00834 HtrA/DegQ protease family signature 225 237 2.5E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_01310 57b1be9cdfb4dc80a3de8a499bed0715 394 PRINTS PR00834 HtrA/DegQ protease family signature 324 341 2.5E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TL08_01310 57b1be9cdfb4dc80a3de8a499bed0715 394 Gene3D G3DSA:2.40.10.10 277 379 1.8E-17 T 12-10-2018 TL08_01310 57b1be9cdfb4dc80a3de8a499bed0715 394 Pfam PF13365 Trypsin-like peptidase domain 217 353 5.0E-21 T 12-10-2018 TL08_01310 57b1be9cdfb4dc80a3de8a499bed0715 394 Pfam PF02674 Colicin V production protein 4 146 2.4E-16 T 12-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 TL08_01310 57b1be9cdfb4dc80a3de8a499bed0715 394 Gene3D G3DSA:2.40.10.10 184 270 1.4E-22 T 12-10-2018 TL08_08490 6935e8e8472976a6b9009729ca134564 217 Gene3D G3DSA:1.10.150.240 17 83 5.8E-21 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TL08_08490 6935e8e8472976a6b9009729ca134564 217 SUPERFAMILY SSF56784 4 214 3.05E-27 T 12-10-2018 IPR036412 HAD-like superfamily TL08_08490 6935e8e8472976a6b9009729ca134564 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 6.1E-12 T 12-10-2018 TL08_08490 6935e8e8472976a6b9009729ca134564 217 Gene3D G3DSA:3.40.50.1000 5 198 5.8E-21 T 12-10-2018 IPR023214 HAD superfamily TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 TIGRFAM TIGR03356 BGL: beta-galactosidase 23 471 4.9E-179 T 12-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 27 41 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 Gene3D G3DSA:3.20.20.80 16 482 3.1E-178 T 12-10-2018 TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 SUPERFAMILY SSF51445 22 482 1.22E-161 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 384 392 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 426 443 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 450 462 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 PRINTS PR00131 Glycosyl hydrolase family 1 signature 405 416 1.0E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_17660 038fe3d2a393ed5e3405261465f8d7e7 490 Pfam PF00232 Glycosyl hydrolase family 1 21 479 7.3E-163 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_10935 8574a8a8980da48f1805a459cc78e805 474 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TL08_10935 8574a8a8980da48f1805a459cc78e805 474 Pfam PF00171 Aldehyde dehydrogenase family 14 467 7.0E-132 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_10935 8574a8a8980da48f1805a459cc78e805 474 Gene3D G3DSA:3.40.605.10 21 461 1.9E-140 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_10935 8574a8a8980da48f1805a459cc78e805 474 Gene3D G3DSA:3.40.309.10 248 436 1.9E-140 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_10935 8574a8a8980da48f1805a459cc78e805 474 SUPERFAMILY SSF53720 2 468 2.75E-132 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_05015 8d5a4255f16b5c2f6b7252af11dce27f 427 SUPERFAMILY SSF103473 22 408 2.35E-41 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_05015 8d5a4255f16b5c2f6b7252af11dce27f 427 Pfam PF05977 Transmembrane secretion effector 21 411 1.8E-22 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_05015 8d5a4255f16b5c2f6b7252af11dce27f 427 Gene3D G3DSA:1.20.1250.20 15 404 8.5E-36 T 12-10-2018 TL08_14375 ac4428f53d3fb01c9d535c9248dd9944 1211 SUPERFAMILY SSF53335 68 490 5.87E-50 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_14375 ac4428f53d3fb01c9d535c9248dd9944 1211 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 238 252 1.2E-6 T 12-10-2018 TL08_14375 ac4428f53d3fb01c9d535c9248dd9944 1211 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 366 378 1.2E-6 T 12-10-2018 TL08_14375 ac4428f53d3fb01c9d535c9248dd9944 1211 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 207 223 1.2E-6 T 12-10-2018 TL08_14375 ac4428f53d3fb01c9d535c9248dd9944 1211 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 369 375 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TL08_14375 ac4428f53d3fb01c9d535c9248dd9944 1211 Gene3D G3DSA:3.40.50.150 190 494 1.3E-36 T 12-10-2018 TL08_01610 a5ccc788ac0bfda6ffd84dfdb36ca06f 597 SMART SM00776 438 595 2.1E-54 T 12-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module TL08_01610 a5ccc788ac0bfda6ffd84dfdb36ca06f 597 SUPERFAMILY SSF56300 44 313 3.04E-28 T 12-10-2018 TL08_01610 a5ccc788ac0bfda6ffd84dfdb36ca06f 597 Pfam PF00149 Calcineurin-like phosphoesterase 43 257 4.0E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_01610 a5ccc788ac0bfda6ffd84dfdb36ca06f 597 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 341 410 1.7E-10 T 12-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TL08_01610 a5ccc788ac0bfda6ffd84dfdb36ca06f 597 Pfam PF08305 NPCBM/NEW2 domain 441 594 2.1E-41 T 12-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module TL08_01610 a5ccc788ac0bfda6ffd84dfdb36ca06f 597 SUPERFAMILY SSF49785 441 594 1.74E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_01610 a5ccc788ac0bfda6ffd84dfdb36ca06f 597 Gene3D G3DSA:3.60.21.10 45 311 7.3E-15 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_01610 a5ccc788ac0bfda6ffd84dfdb36ca06f 597 Gene3D G3DSA:2.60.120.1060 435 594 2.6E-44 T 12-10-2018 IPR038637 NPCBM domain superfamily TL08_09495 3c7fa43cbb167cf87b16e46fcd11d92f 313 Pfam PF08478 POTRA domain, FtsQ-type 123 190 4.3E-16 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type TL08_09495 3c7fa43cbb167cf87b16e46fcd11d92f 313 Pfam PF03799 Cell division protein FtsQ 203 296 2.1E-6 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB TL08_09495 3c7fa43cbb167cf87b16e46fcd11d92f 313 Gene3D G3DSA:3.10.20.310 122 189 4.8E-6 T 12-10-2018 TL08_08840 0131f0010dc562c9c078dd92bd043a1b 128 Pfam PF02021 Uncharacterised protein family UPF0102 21 111 1.0E-26 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 TL08_08840 0131f0010dc562c9c078dd92bd043a1b 128 Gene3D G3DSA:3.40.1350.10 21 127 2.5E-27 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TL08_08840 0131f0010dc562c9c078dd92bd043a1b 128 SUPERFAMILY SSF52980 20 117 1.88E-20 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TL08_08840 0131f0010dc562c9c078dd92bd043a1b 128 Hamap MF_00048 UPF0102 protein YraN [yraN]. 14 124 21.104 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 TL08_02005 23582e67e347e8d4004ee33851eed967 300 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 47 262 4.4E-31 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase TL08_02005 23582e67e347e8d4004ee33851eed967 300 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 24 299 4.3E-131 T 12-10-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 TL08_02005 23582e67e347e8d4004ee33851eed967 300 Gene3D G3DSA:2.60.120.620 3 298 4.1E-102 T 12-10-2018 TL08_02005 23582e67e347e8d4004ee33851eed967 300 SUPERFAMILY SSF51197 35 298 6.13E-57 T 12-10-2018 TL08_13965 28e323740a9b21df66f69763b4095b62 316 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 13 162 1.1E-19 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TL08_13965 28e323740a9b21df66f69763b4095b62 316 PIRSF PIRSF000103 5 301 4.9E-35 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TL08_13965 28e323740a9b21df66f69763b4095b62 316 SUPERFAMILY SSF48179 173 296 4.19E-7 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_13965 28e323740a9b21df66f69763b4095b62 316 SUPERFAMILY SSF51735 13 166 3.25E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_13965 28e323740a9b21df66f69763b4095b62 316 Gene3D G3DSA:3.40.50.720 3 166 2.8E-38 T 12-10-2018 TL08_13965 28e323740a9b21df66f69763b4095b62 316 Gene3D G3DSA:1.10.1040.10 167 299 1.1E-43 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TL08_10085 d79bf9f4b1f14c8477ab478bdb72b64a 227 SUPERFAMILY SSF48498 100 188 3.34E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_10085 d79bf9f4b1f14c8477ab478bdb72b64a 227 Gene3D G3DSA:1.10.10.60 20 65 1.7E-19 T 12-10-2018 TL08_10085 d79bf9f4b1f14c8477ab478bdb72b64a 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 5.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_10085 d79bf9f4b1f14c8477ab478bdb72b64a 227 Gene3D G3DSA:1.10.357.10 66 212 1.2E-16 T 12-10-2018 TL08_10085 d79bf9f4b1f14c8477ab478bdb72b64a 227 SUPERFAMILY SSF46689 19 77 2.0E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 Gene3D G3DSA:3.30.70.80 53 123 1.5E-14 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 170 181 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 SUPERFAMILY SSF52743 137 407 3.14E-75 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 Gene3D G3DSA:3.40.50.200 136 412 1.5E-89 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 Pfam PF05922 Peptidase inhibitor I9 80 129 1.7E-6 T 12-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 207 217 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 357 367 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 203 216 4.8E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 356 372 4.8E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 165 184 4.8E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 Pfam PF00082 Subtilase family 172 394 3.6E-34 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_07405 c14333c9f2cf61a7c36681af4847b109 413 SUPERFAMILY SSF54897 58 129 8.5E-12 T 12-10-2018 TL08_12425 63cd3b8ed88d5044c463114fc74c74be 301 SUPERFAMILY SSF51735 6 272 5.34E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_12425 63cd3b8ed88d5044c463114fc74c74be 301 Gene3D G3DSA:3.40.50.720 6 289 1.6E-66 T 12-10-2018 TL08_12425 63cd3b8ed88d5044c463114fc74c74be 301 Gene3D G3DSA:3.90.25.10 163 295 1.6E-66 T 12-10-2018 TL08_12425 63cd3b8ed88d5044c463114fc74c74be 301 Pfam PF05368 NmrA-like family 6 244 2.2E-43 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 TL08_03795 10708d215f933419944272eb7ee36cbf 495 Pfam PF00450 Serine carboxypeptidase 82 455 3.3E-10 T 12-10-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 TL08_03795 10708d215f933419944272eb7ee36cbf 495 SUPERFAMILY SSF53474 31 490 3.28E-72 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_03795 10708d215f933419944272eb7ee36cbf 495 Gene3D G3DSA:3.40.50.1820 34 274 5.2E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_25280 55aad6a1c2020bf986cdfc42b7df972b 345 SMART SM00852 1 142 2.9E-13 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_25280 55aad6a1c2020bf986cdfc42b7df972b 345 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 136 3.0E-27 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_25280 55aad6a1c2020bf986cdfc42b7df972b 345 SUPERFAMILY SSF53218 1 147 1.7E-37 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TL08_25280 55aad6a1c2020bf986cdfc42b7df972b 345 SUPERFAMILY SSF54690 221 343 1.24E-33 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TL08_25280 55aad6a1c2020bf986cdfc42b7df972b 345 Pfam PF02391 MoaE protein 216 325 1.6E-27 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TL08_25280 55aad6a1c2020bf986cdfc42b7df972b 345 Gene3D G3DSA:3.90.1170.40 192 343 1.3E-38 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TL08_25280 55aad6a1c2020bf986cdfc42b7df972b 345 Gene3D G3DSA:3.40.980.10 1 153 2.9E-48 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TL08_25280 55aad6a1c2020bf986cdfc42b7df972b 345 Pfam PF00994 Probable molybdopterin binding domain 1 141 1.0E-25 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_25280 55aad6a1c2020bf986cdfc42b7df972b 345 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 58 71 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Gene3D G3DSA:2.60.40.10 1053 1133 5.4E-16 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Pfam PF07995 Glucose / Sorbosone dehydrogenase 264 524 2.0E-32 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 SUPERFAMILY SSF52317 18 243 2.2E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Gene3D G3DSA:3.40.50.880 4 242 3.8E-77 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 SUPERFAMILY SSF49785 906 1039 1.7E-16 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Gene3D G3DSA:2.60.120.260 903 1040 2.0E-25 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 SUPERFAMILY SSF49299 709 796 5.36E-17 T 12-10-2018 IPR035986 PKD domain superfamily TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 SMART SM00089 711 797 1.4E-10 T 12-10-2018 IPR022409 PKD/Chitinase domain TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 SMART SM00089 1052 1133 4.3E-14 T 12-10-2018 IPR022409 PKD/Chitinase domain TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 SMART SM00606 902 1041 4.9E-16 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Gene3D G3DSA:2.60.40.10 700 795 5.1E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 SUPERFAMILY SSF49299 1055 1132 6.41E-15 T 12-10-2018 IPR035986 PKD domain superfamily TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Gene3D G3DSA:2.120.10.30 243 640 5.9E-73 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Pfam PF03422 Carbohydrate binding module (family 6) 920 1040 9.3E-17 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 SUPERFAMILY SSF50952 252 685 2.88E-17 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Pfam PF00801 PKD domain 721 780 7.6E-10 T 12-10-2018 IPR000601 PKD domain TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Pfam PF00801 PKD domain 1056 1121 5.9E-11 T 12-10-2018 IPR000601 PKD domain TL08_13000 51e7359269d95c1c205e33c75dc961f3 1133 Pfam PF06283 Trehalose utilisation 21 237 5.3E-72 T 12-10-2018 IPR029010 ThuA-like domain TL08_17195 b0325b26c7069f1dfcac9cafebab9ec3 216 Pfam PF01323 DSBA-like thioredoxin domain 8 208 6.4E-50 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 TL08_17195 b0325b26c7069f1dfcac9cafebab9ec3 216 Gene3D G3DSA:3.40.30.10 1 211 1.1E-74 T 12-10-2018 TL08_17195 b0325b26c7069f1dfcac9cafebab9ec3 216 SUPERFAMILY SSF52833 6 214 5.87E-49 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_23140 afa8455732e40f8e9d3d95df273b189e 204 SUPERFAMILY SSF51182 2 197 1.4E-70 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_23140 afa8455732e40f8e9d3d95df273b189e 204 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 178 2.0E-64 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TL08_23140 afa8455732e40f8e9d3d95df273b189e 204 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 178 1.6E-46 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TL08_23140 afa8455732e40f8e9d3d95df273b189e 204 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 2.3E-59 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TL08_23140 afa8455732e40f8e9d3d95df273b189e 204 Gene3D G3DSA:2.60.120.10 1 202 4.0E-71 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_26940 4f6742979ef28f5edd10e57685d8fb4e 392 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 381 1.3E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_26940 4f6742979ef28f5edd10e57685d8fb4e 392 SUPERFAMILY SSF55874 277 382 4.58E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_26940 4f6742979ef28f5edd10e57685d8fb4e 392 Gene3D G3DSA:3.30.565.10 263 382 7.4E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_26940 4f6742979ef28f5edd10e57685d8fb4e 392 SMART SM00387 285 384 4.5E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_26195 34e578ca4ca1841fed1f4526fcfb466d 344 SUPERFAMILY SSF51569 4 340 3.66E-96 T 12-10-2018 TL08_26195 34e578ca4ca1841fed1f4526fcfb466d 344 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 340 4.1E-80 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TL08_26195 34e578ca4ca1841fed1f4526fcfb466d 344 Gene3D G3DSA:3.20.20.70 1 344 2.3E-127 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_26195 34e578ca4ca1841fed1f4526fcfb466d 344 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TL08_26195 34e578ca4ca1841fed1f4526fcfb466d 344 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 340 1.4E-73 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TL08_26195 34e578ca4ca1841fed1f4526fcfb466d 344 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TL08_26195 34e578ca4ca1841fed1f4526fcfb466d 344 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 339 2.1E-141 T 12-10-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TL08_26195 34e578ca4ca1841fed1f4526fcfb466d 344 PIRSF PIRSF001359 6 341 6.3E-65 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TL08_23030 b4bc356332405b690dda9fa54de448b0 179 Gene3D G3DSA:1.10.10.10 1 84 3.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23030 b4bc356332405b690dda9fa54de448b0 179 SUPERFAMILY SSF46785 3 174 4.57E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23030 b4bc356332405b690dda9fa54de448b0 179 Pfam PF03551 Transcriptional regulator PadR-like family 5 77 1.3E-7 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal TL08_23030 b4bc356332405b690dda9fa54de448b0 179 Pfam PF10400 Virulence activator alpha C-term 94 171 7.2E-7 T 12-10-2018 IPR018309 Transcription regulator PadR, C-terminal TL08_15560 23e9be99680589b70592f6a86e00442b 186 Gene3D G3DSA:3.30.460.10 1 171 6.9E-50 T 12-10-2018 TL08_15560 23e9be99680589b70592f6a86e00442b 186 SUPERFAMILY SSF81301 6 165 3.6E-45 T 12-10-2018 TL08_15560 23e9be99680589b70592f6a86e00442b 186 Pfam PF04229 GrpB protein 5 164 2.0E-45 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase TL08_18220 498b03bae1960935ef6d052c8330e3fa 863 Gene3D G3DSA:3.30.470.20 188 332 1.6E-41 T 12-10-2018 TL08_18220 498b03bae1960935ef6d052c8330e3fa 863 Gene3D G3DSA:3.30.1490.20 2 186 1.4E-58 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TL08_18220 498b03bae1960935ef6d052c8330e3fa 863 Pfam PF00391 PEP-utilising enzyme, mobile domain 781 852 1.5E-22 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TL08_18220 498b03bae1960935ef6d052c8330e3fa 863 Gene3D G3DSA:3.50.30.10 753 859 8.9E-30 T 12-10-2018 TL08_18220 498b03bae1960935ef6d052c8330e3fa 863 SUPERFAMILY SSF56059 16 358 1.15E-89 T 12-10-2018 TL08_18220 498b03bae1960935ef6d052c8330e3fa 863 SUPERFAMILY SSF52009 753 855 5.62E-26 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TL08_18220 498b03bae1960935ef6d052c8330e3fa 863 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 22 322 1.3E-92 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TL08_08830 74e5d57c50d10e3fa264a66845fbd963 817 SUPERFAMILY SSF49785 2 186 7.37E-49 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_08830 74e5d57c50d10e3fa264a66845fbd963 817 Gene3D G3DSA:3.20.20.80 295 634 2.2E-115 T 12-10-2018 TL08_08830 74e5d57c50d10e3fa264a66845fbd963 817 Gene3D G3DSA:2.60.120.260 2 191 5.5E-58 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_08830 74e5d57c50d10e3fa264a66845fbd963 817 Pfam PF00703 Glycosyl hydrolases family 2 234 295 9.2E-6 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 TL08_08830 74e5d57c50d10e3fa264a66845fbd963 817 Gene3D G3DSA:2.60.40.10 727 804 4.6E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_08830 74e5d57c50d10e3fa264a66845fbd963 817 SUPERFAMILY SSF51445 292 634 3.14E-102 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_08830 74e5d57c50d10e3fa264a66845fbd963 817 Gene3D G3DSA:2.60.40.10 194 294 3.2E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_08830 74e5d57c50d10e3fa264a66845fbd963 817 SUPERFAMILY SSF49303 191 295 1.78E-15 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily TL08_01050 26a0fd53aa20ddb83603a58bce398325 345 Pfam PF13407 Periplasmic binding protein domain 66 319 9.6E-67 T 12-10-2018 IPR025997 Periplasmic binding protein TL08_01050 26a0fd53aa20ddb83603a58bce398325 345 Gene3D G3DSA:3.40.50.2300 165 337 2.6E-82 T 12-10-2018 TL08_01050 26a0fd53aa20ddb83603a58bce398325 345 SUPERFAMILY SSF53822 66 340 1.32E-69 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_01050 26a0fd53aa20ddb83603a58bce398325 345 Gene3D G3DSA:3.40.50.2300 73 329 2.6E-82 T 12-10-2018 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 Gene3D G3DSA:4.10.870.10 609 680 5.5E-291 T 12-10-2018 IPR027390 Endoglucanase F, domain 3 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 SUPERFAMILY SSF48208 58 699 1.02E-267 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 Pfam PF02011 Glycosyl hydrolase family 48 63 697 7.1E-290 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 Gene3D G3DSA:2.170.160.10 150 382 5.5E-291 T 12-10-2018 IPR023309 Endoglucanase F, domain 2 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 89 114 6.5E-97 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 115 132 6.5E-97 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 231 255 6.5E-97 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 466 492 6.5E-97 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 521 541 6.5E-97 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 349 368 6.5E-97 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 630 658 6.5E-97 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 420 443 6.5E-97 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 276 303 6.5E-97 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 TL08_17650 0b6b68b8f9466da5e46772c8eea132f8 701 Gene3D G3DSA:1.50.10.10 63 697 5.5E-291 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_18590 3d5e4d6825cea63be3e9d4c7ac4493ab 140 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 93 5.8E-9 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_18590 3d5e4d6825cea63be3e9d4c7ac4493ab 140 Gene3D G3DSA:2.30.110.10 1 138 7.9E-21 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_18590 3d5e4d6825cea63be3e9d4c7ac4493ab 140 SUPERFAMILY SSF50475 3 138 2.99E-22 T 12-10-2018 TL08_02650 e4f54de00b50779b44b1f66fe5977809 338 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 49 196 2.8E-34 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02650 e4f54de00b50779b44b1f66fe5977809 338 Gene3D G3DSA:1.20.120.1200 37 200 1.5E-42 T 12-10-2018 TL08_03160 bf87b34f45f702f283c832d3e4a76102 415 Gene3D G3DSA:3.30.565.10 300 412 7.1E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_03160 bf87b34f45f702f283c832d3e4a76102 415 SUPERFAMILY SSF55874 303 411 3.16E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_03160 bf87b34f45f702f283c832d3e4a76102 415 Pfam PF07730 Histidine kinase 224 291 1.4E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_03160 bf87b34f45f702f283c832d3e4a76102 415 Pfam PF13796 Putative sensor 30 195 9.8E-21 T 12-10-2018 IPR025828 Putative sensor domain TL08_01905 230dc8848965f9c1e37bd6db3aed5032 151 PRINTS PR00502 NUDIX hydrolase family signature 41 56 6.2E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_01905 230dc8848965f9c1e37bd6db3aed5032 151 PRINTS PR00502 NUDIX hydrolase family signature 27 41 6.2E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_01905 230dc8848965f9c1e37bd6db3aed5032 151 Pfam PF00293 NUDIX domain 6 115 3.3E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_01905 230dc8848965f9c1e37bd6db3aed5032 151 Gene3D G3DSA:3.90.79.10 2 134 1.2E-27 T 12-10-2018 TL08_01905 230dc8848965f9c1e37bd6db3aed5032 151 ProSitePatterns PS00893 Nudix box signature. 32 53 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_01905 230dc8848965f9c1e37bd6db3aed5032 151 SUPERFAMILY SSF55811 3 125 1.33E-26 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_17675 598038064a43c4dad2f918b37cb84d14 424 SUPERFAMILY SSF53850 32 421 7.25E-40 T 12-10-2018 TL08_17675 598038064a43c4dad2f918b37cb84d14 424 Pfam PF13416 Bacterial extracellular solute-binding protein 49 352 1.7E-27 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_17675 598038064a43c4dad2f918b37cb84d14 424 Gene3D G3DSA:3.40.190.10 147 412 8.9E-53 T 12-10-2018 TL08_17675 598038064a43c4dad2f918b37cb84d14 424 Gene3D G3DSA:3.40.190.10 51 351 8.9E-53 T 12-10-2018 TL08_13675 6db6581a7335c207e9625c3a2e773fd1 362 Pfam PF13377 Periplasmic binding protein-like domain 201 361 4.8E-29 T 12-10-2018 TL08_13675 6db6581a7335c207e9625c3a2e773fd1 362 SUPERFAMILY SSF47413 6 52 5.16E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_13675 6db6581a7335c207e9625c3a2e773fd1 362 Gene3D G3DSA:1.10.260.40 1 60 2.2E-17 T 12-10-2018 TL08_13675 6db6581a7335c207e9625c3a2e773fd1 362 Gene3D G3DSA:3.40.50.2300 192 323 1.5E-50 T 12-10-2018 TL08_13675 6db6581a7335c207e9625c3a2e773fd1 362 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 51 2.8E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_13675 6db6581a7335c207e9625c3a2e773fd1 362 Gene3D G3DSA:3.40.50.2300 111 341 1.5E-50 T 12-10-2018 TL08_13675 6db6581a7335c207e9625c3a2e773fd1 362 SUPERFAMILY SSF53822 104 361 7.26E-48 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_13675 6db6581a7335c207e9625c3a2e773fd1 362 SMART SM00354 6 77 5.4E-8 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_17425 d7cb02543cedc2af7886eee16e9bbef9 285 SUPERFAMILY SSF51658 1 262 9.03E-57 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_17425 d7cb02543cedc2af7886eee16e9bbef9 285 Gene3D G3DSA:3.20.20.150 1 284 8.7E-68 T 12-10-2018 TL08_17425 d7cb02543cedc2af7886eee16e9bbef9 285 Pfam PF01261 Xylose isomerase-like TIM barrel 27 216 5.5E-26 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_15760 85cb0bbe459191d1b08a729777307f5b 1033 Gene3D G3DSA:3.30.465.40 34 210 8.2E-39 T 12-10-2018 TL08_15760 85cb0bbe459191d1b08a729777307f5b 1033 Pfam PF13183 4Fe-4S dicluster domain 574 657 5.5E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TL08_15760 85cb0bbe459191d1b08a729777307f5b 1033 SUPERFAMILY SSF56176 24 281 1.23E-47 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_15760 85cb0bbe459191d1b08a729777307f5b 1033 Gene3D G3DSA:3.30.70.2740 413 495 1.5E-5 T 12-10-2018 TL08_15760 85cb0bbe459191d1b08a729777307f5b 1033 SUPERFAMILY SSF55103 286 546 1.28E-48 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TL08_15760 85cb0bbe459191d1b08a729777307f5b 1033 Pfam PF02754 Cysteine-rich domain 765 837 0.0086 T 12-10-2018 IPR004017 Cysteine-rich domain TL08_15760 85cb0bbe459191d1b08a729777307f5b 1033 Pfam PF01565 FAD binding domain 58 196 1.7E-38 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TL08_15760 85cb0bbe459191d1b08a729777307f5b 1033 Pfam PF02913 FAD linked oxidases, C-terminal domain 285 535 3.5E-43 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TL08_15760 85cb0bbe459191d1b08a729777307f5b 1033 SUPERFAMILY SSF46548 572 661 5.49E-9 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TL08_18060 b1b848af49e68fcac5e31c1d93eea568 321 Gene3D G3DSA:1.25.40.10 71 219 3.8E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_19705 5cccf1bd9263121c1f9ac19a49975699 112 SMART SM00418 11 89 3.8E-16 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_19705 5cccf1bd9263121c1f9ac19a49975699 112 Gene3D G3DSA:1.10.10.10 2 112 2.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19705 5cccf1bd9263121c1f9ac19a49975699 112 Pfam PF12840 Helix-turn-helix domain 10 69 1.2E-14 T 12-10-2018 TL08_19705 5cccf1bd9263121c1f9ac19a49975699 112 SUPERFAMILY SSF46785 9 101 2.79E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_19705 5cccf1bd9263121c1f9ac19a49975699 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 7.0E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_19705 5cccf1bd9263121c1f9ac19a49975699 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 7.0E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_19705 5cccf1bd9263121c1f9ac19a49975699 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 7.0E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_24445 c2d33a028e21fb43fcbf2291b66b361e 471 Gene3D G3DSA:3.40.710.10 77 373 9.3E-70 T 12-10-2018 TL08_24445 c2d33a028e21fb43fcbf2291b66b361e 471 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 211 224 3.3E-8 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TL08_24445 c2d33a028e21fb43fcbf2291b66b361e 471 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 185 202 3.3E-8 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TL08_24445 c2d33a028e21fb43fcbf2291b66b361e 471 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 137 148 3.3E-8 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TL08_24445 c2d33a028e21fb43fcbf2291b66b361e 471 SUPERFAMILY SSF56601 99 344 8.2E-47 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_24445 c2d33a028e21fb43fcbf2291b66b361e 471 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 101 325 4.1E-29 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 Pfam PF00232 Glycosyl hydrolase family 1 23 470 3.0E-151 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 2.4E-20 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 2.4E-20 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 375 383 2.4E-20 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 396 407 2.4E-20 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 434 2.4E-20 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 SUPERFAMILY SSF51445 23 473 3.32E-156 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 TIGRFAM TIGR03356 BGL: beta-galactosidase 24 462 2.9E-176 T 12-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 28 42 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TL08_07050 c78c45aa61d656eef5900d29210fc6d0 479 Gene3D G3DSA:3.20.20.80 16 473 1.4E-164 T 12-10-2018 TL08_26885 40f68de1dcd1fd2347fa362e01f17242 88 Pfam PF13560 Helix-turn-helix domain 16 76 6.6E-11 T 12-10-2018 TL08_26885 40f68de1dcd1fd2347fa362e01f17242 88 SMART SM00530 20 74 4.2E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_26885 40f68de1dcd1fd2347fa362e01f17242 88 SUPERFAMILY SSF47413 7 77 5.63E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_26885 40f68de1dcd1fd2347fa362e01f17242 88 Gene3D G3DSA:1.10.260.40 7 76 7.4E-26 T 12-10-2018 TL08_05570 5911a1a8a9081cdc7339367d0ec54583 417 SUPERFAMILY SSF103473 14 406 1.7E-53 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_05570 5911a1a8a9081cdc7339367d0ec54583 417 Pfam PF07690 Major Facilitator Superfamily 28 320 3.0E-25 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_05570 5911a1a8a9081cdc7339367d0ec54583 417 Gene3D G3DSA:1.20.1250.20 16 396 3.2E-39 T 12-10-2018 TL08_17915 ab738e5c30f7367365a3b043259a972c 738 Gene3D G3DSA:3.40.50.920 610 737 8.0E-25 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_17915 ab738e5c30f7367365a3b043259a972c 738 Pfam PF00676 Dehydrogenase E1 component 70 348 3.7E-24 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TL08_17915 ab738e5c30f7367365a3b043259a972c 738 Pfam PF02779 Transketolase, pyrimidine binding domain 401 575 2.4E-26 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_17915 ab738e5c30f7367365a3b043259a972c 738 SUPERFAMILY SSF52518 33 364 3.09E-48 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_17915 ab738e5c30f7367365a3b043259a972c 738 Gene3D G3DSA:3.40.50.970 399 596 1.4E-61 T 12-10-2018 TL08_17915 ab738e5c30f7367365a3b043259a972c 738 SMART SM00861 401 582 6.3E-44 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_17915 ab738e5c30f7367365a3b043259a972c 738 Pfam PF02780 Transketolase, C-terminal domain 611 721 1.4E-21 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TL08_17915 ab738e5c30f7367365a3b043259a972c 738 SUPERFAMILY SSF52518 400 585 9.91E-46 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_17915 ab738e5c30f7367365a3b043259a972c 738 SUPERFAMILY SSF52922 608 737 2.09E-27 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_17915 ab738e5c30f7367365a3b043259a972c 738 Gene3D G3DSA:3.40.50.970 17 365 2.6E-57 T 12-10-2018 TL08_16215 cbf2ffdb320335542bf3a8cea09b9f66 65 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.7E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_16215 cbf2ffdb320335542bf3a8cea09b9f66 65 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.7E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_16215 cbf2ffdb320335542bf3a8cea09b9f66 65 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.7E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_16215 cbf2ffdb320335542bf3a8cea09b9f66 65 SUPERFAMILY SSF54862 2 62 9.43E-17 T 12-10-2018 TL08_16215 cbf2ffdb320335542bf3a8cea09b9f66 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 4.7E-15 T 12-10-2018 TL08_16215 cbf2ffdb320335542bf3a8cea09b9f66 65 Gene3D G3DSA:3.30.70.20 1 63 4.3E-22 T 12-10-2018 TL08_11510 7e6d0d45c9a898b48051021b8b430824 105 Gene3D G3DSA:1.10.8.50 1 105 1.1E-43 T 12-10-2018 TL08_11510 7e6d0d45c9a898b48051021b8b430824 105 PIRSF PIRSF002134 37 105 2.3E-5 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_11510 7e6d0d45c9a898b48051021b8b430824 105 SUPERFAMILY SSF46946 54 103 5.1E-6 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TL08_04855 1c86a9dcb36dc30f3eabe7724e967f62 566 Pfam PF09972 Predicted membrane protein (DUF2207) 38 506 6.7E-44 T 12-10-2018 IPR018702 Protein of unknown function DUF2207, membrane TL08_17485 bac18c398f4e24e6426fb4a9ffd2fb63 141 Pfam PF06841 T4-like virus tail tube protein gp19 9 138 8.9E-32 T 12-10-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 TL08_17485 bac18c398f4e24e6426fb4a9ffd2fb63 141 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 7 138 6.5E-26 T 12-10-2018 IPR011747 Conserved hypothetical protein CHP02241 TL08_21245 c4a9c97f8b2d50e71634f24bd34b306b 387 SUPERFAMILY SSF56574 20 386 1.44E-83 T 12-10-2018 IPR036186 Serpin superfamily TL08_21245 c4a9c97f8b2d50e71634f24bd34b306b 387 Gene3D G3DSA:2.30.39.10 189 386 3.4E-84 T 12-10-2018 TL08_21245 c4a9c97f8b2d50e71634f24bd34b306b 387 Pfam PF00079 Serpin (serine protease inhibitor) 22 386 6.1E-79 T 12-10-2018 IPR023796 Serpin domain TL08_21245 c4a9c97f8b2d50e71634f24bd34b306b 387 SMART SM00093 26 386 6.8E-68 T 12-10-2018 IPR023796 Serpin domain TL08_21245 c4a9c97f8b2d50e71634f24bd34b306b 387 Gene3D G3DSA:3.30.497.10 24 331 3.4E-84 T 12-10-2018 TL08_21245 c4a9c97f8b2d50e71634f24bd34b306b 387 ProSitePatterns PS00284 Serpins signature. 359 369 - T 12-10-2018 IPR023795 Serpin, conserved site TL08_23305 4c1eb2e80669369dad32b883b45a5396 216 SUPERFAMILY SSF52540 6 201 1.7E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23305 4c1eb2e80669369dad32b883b45a5396 216 Gene3D G3DSA:3.40.50.300 7 208 1.3E-48 T 12-10-2018 TL08_23305 4c1eb2e80669369dad32b883b45a5396 216 Pfam PF02223 Thymidylate kinase 10 170 4.2E-18 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TL08_23305 4c1eb2e80669369dad32b883b45a5396 216 Hamap MF_00165 Thymidylate kinase [tmk]. 6 215 13.102 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TL08_12415 e6db00f3e52ad3b8a4ca89e2aaafbf3c 218 Pfam PF11706 CGNR zinc finger 172 215 3.3E-18 T 12-10-2018 IPR021005 Zinc finger, CGNR TL08_12415 e6db00f3e52ad3b8a4ca89e2aaafbf3c 218 Gene3D G3DSA:1.10.3300.10 80 216 3.5E-20 T 12-10-2018 IPR023286 ABATE domain superfamily TL08_12415 e6db00f3e52ad3b8a4ca89e2aaafbf3c 218 Pfam PF07336 Putative stress-induced transcription regulator 13 159 2.8E-7 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator TL08_12415 e6db00f3e52ad3b8a4ca89e2aaafbf3c 218 SUPERFAMILY SSF160904 10 214 7.45E-28 T 12-10-2018 TL08_14200 4c794323db3fb5cd6b793424f202c9ff 302 Gene3D G3DSA:3.40.50.720 122 250 5.0E-71 T 12-10-2018 TL08_14200 4c794323db3fb5cd6b793424f202c9ff 302 SUPERFAMILY SSF50129 1 135 1.11E-31 T 12-10-2018 IPR011032 GroES-like superfamily TL08_14200 4c794323db3fb5cd6b793424f202c9ff 302 SUPERFAMILY SSF51735 111 219 5.13E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14200 4c794323db3fb5cd6b793424f202c9ff 302 Pfam PF00107 Zinc-binding dehydrogenase 148 219 6.8E-13 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_14200 4c794323db3fb5cd6b793424f202c9ff 302 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 5.5E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_14200 4c794323db3fb5cd6b793424f202c9ff 302 SMART SM00829 10 299 1.3E-12 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_14200 4c794323db3fb5cd6b793424f202c9ff 302 Gene3D G3DSA:3.90.180.10 8 297 5.0E-71 T 12-10-2018 TL08_17255 c76ceeaf7af5f4627176a85f3c28718c 231 SUPERFAMILY SSF46689 29 106 2.82E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_17255 c76ceeaf7af5f4627176a85f3c28718c 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 46 86 5.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_17255 c76ceeaf7af5f4627176a85f3c28718c 231 Gene3D G3DSA:1.10.357.10 32 231 1.4E-47 T 12-10-2018 TL08_17255 c76ceeaf7af5f4627176a85f3c28718c 231 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 111 224 1.7E-27 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal TL08_17255 c76ceeaf7af5f4627176a85f3c28718c 231 SUPERFAMILY SSF48498 111 224 2.37E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_06675 82d75473c6afbd9d7cc635652755f2b5 260 Pfam PF01012 Electron transfer flavoprotein domain 25 208 3.3E-47 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TL08_06675 82d75473c6afbd9d7cc635652755f2b5 260 SMART SM00893 23 213 6.6E-52 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TL08_06675 82d75473c6afbd9d7cc635652755f2b5 260 PIRSF PIRSF000090 1 260 1.3E-83 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 TL08_06675 82d75473c6afbd9d7cc635652755f2b5 260 Gene3D G3DSA:3.40.50.620 1 260 3.1E-86 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_06675 82d75473c6afbd9d7cc635652755f2b5 260 SUPERFAMILY SSF52402 1 254 9.07E-74 T 12-10-2018 TL08_23710 39a810542a7246f726213b24fe3b7238 568 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 282 6.4E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_23710 39a810542a7246f726213b24fe3b7238 568 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 380 559 5.3E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_23710 39a810542a7246f726213b24fe3b7238 568 Gene3D G3DSA:1.10.3720.10 13 288 3.2E-44 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23710 39a810542a7246f726213b24fe3b7238 568 SUPERFAMILY SSF161098 8 282 6.82E-48 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23710 39a810542a7246f726213b24fe3b7238 568 SUPERFAMILY SSF161098 301 557 9.35E-41 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23710 39a810542a7246f726213b24fe3b7238 568 Gene3D G3DSA:1.10.3720.10 305 564 4.8E-37 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15285 cd6556ec50815491090b8503bd35c579 254 Pfam PF13847 Methyltransferase domain 37 139 6.0E-10 T 12-10-2018 IPR025714 Methyltransferase domain TL08_15285 cd6556ec50815491090b8503bd35c579 254 Gene3D G3DSA:3.40.50.150 1 247 3.6E-62 T 12-10-2018 TL08_15285 cd6556ec50815491090b8503bd35c579 254 SUPERFAMILY SSF53335 20 246 6.44E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_12190 b70137409c62db83b26be4b8c0827883 200 Pfam PF00486 Transcriptional regulatory protein, C terminal 108 179 3.8E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_12190 b70137409c62db83b26be4b8c0827883 200 SMART SM00862 106 180 1.7E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_12190 b70137409c62db83b26be4b8c0827883 200 SUPERFAMILY SSF46894 93 181 2.92E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_12190 b70137409c62db83b26be4b8c0827883 200 Gene3D G3DSA:1.10.10.10 90 191 1.4E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 6 327 36.752 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 192 213 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 SUPERFAMILY SSF51735 7 183 1.18E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 Gene3D G3DSA:1.10.1040.10 193 338 1.3E-49 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 PIRSF PIRSF000114 2 337 3.1E-102 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 SUPERFAMILY SSF48179 183 336 2.21E-52 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 162 6.7E-52 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 202 226 1.3E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 10 27 1.3E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 177 201 1.3E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 137 157 1.3E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 242 259 1.3E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 60 87 1.3E-48 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 184 323 1.7E-51 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TL08_22615 4ad0bebba2f59473fb91fab440d04c22 338 Gene3D G3DSA:3.40.50.720 1 191 7.7E-64 T 12-10-2018 TL08_04470 3598a2612899e43579d44f62ca87d5af 371 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 14 367 1.5E-166 T 12-10-2018 IPR019880 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase OxyQ TL08_04470 3598a2612899e43579d44f62ca87d5af 371 Gene3D G3DSA:3.90.1150.10 33 360 3.4E-79 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_04470 3598a2612899e43579d44f62ca87d5af 371 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 225 238 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TL08_04470 3598a2612899e43579d44f62ca87d5af 371 Pfam PF00155 Aminotransferase class I and II 37 367 1.8E-41 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_04470 3598a2612899e43579d44f62ca87d5af 371 Gene3D G3DSA:3.40.640.10 48 274 3.4E-79 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_04470 3598a2612899e43579d44f62ca87d5af 371 SUPERFAMILY SSF53383 13 368 1.05E-77 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_25070 ffd697e34aac119a58f56bbd5a5a24fd 268 SUPERFAMILY SSF55729 151 244 4.95E-12 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_25070 ffd697e34aac119a58f56bbd5a5a24fd 268 Pfam PF08445 FR47-like protein 183 245 4.1E-8 T 12-10-2018 IPR013653 FR47-like GO:0016747 TL08_25070 ffd697e34aac119a58f56bbd5a5a24fd 268 Gene3D G3DSA:3.40.630.30 35 249 2.7E-20 T 12-10-2018 TL08_25905 f37caaac73dcd6b892479eea5ed0cbf6 338 Gene3D G3DSA:3.40.630.30 2 338 4.8E-84 T 12-10-2018 TL08_25905 f37caaac73dcd6b892479eea5ed0cbf6 338 Pfam PF00583 Acetyltransferase (GNAT) family 67 120 7.0E-6 T 12-10-2018 IPR000182 GNAT domain TL08_25905 f37caaac73dcd6b892479eea5ed0cbf6 338 Pfam PF00583 Acetyltransferase (GNAT) family 233 327 8.0E-16 T 12-10-2018 IPR000182 GNAT domain TL08_25905 f37caaac73dcd6b892479eea5ed0cbf6 338 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 143 335 1.6E-71 T 12-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 TL08_25905 f37caaac73dcd6b892479eea5ed0cbf6 338 SUPERFAMILY SSF55729 62 330 1.96E-41 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_25905 f37caaac73dcd6b892479eea5ed0cbf6 338 PIRSF PIRSF021524 2 338 6.3E-104 T 12-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 TL08_25905 f37caaac73dcd6b892479eea5ed0cbf6 338 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 7 338 33.651 T 12-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 TL08_23220 0ee0811bd6f50268e4fab343bca8592b 300 SUPERFAMILY SSF89392 64 287 2.31E-7 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX TL08_23220 0ee0811bd6f50268e4fab343bca8592b 300 Gene3D G3DSA:2.50.20.20 58 287 2.4E-5 T 12-10-2018 TL08_04765 552c5db8090d0a239dea1b024b442fe0 228 SUPERFAMILY SSF47240 23 171 4.77E-7 T 12-10-2018 IPR009078 Ferritin-like superfamily TL08_04765 552c5db8090d0a239dea1b024b442fe0 228 Gene3D G3DSA:1.20.1260.10 10 228 2.2E-74 T 12-10-2018 IPR012347 Ferritin-like TL08_04765 552c5db8090d0a239dea1b024b442fe0 228 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 21 200 1.7E-78 T 12-10-2018 TL08_06880 42026783c937826c422fc2e294b0c0c4 197 Pfam PF01381 Helix-turn-helix 18 72 8.3E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_06880 42026783c937826c422fc2e294b0c0c4 197 Pfam PF07883 Cupin domain 119 174 1.1E-9 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TL08_06880 42026783c937826c422fc2e294b0c0c4 197 SUPERFAMILY SSF47413 13 78 8.16E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_06880 42026783c937826c422fc2e294b0c0c4 197 Gene3D G3DSA:2.60.120.10 96 195 5.2E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_06880 42026783c937826c422fc2e294b0c0c4 197 Gene3D G3DSA:1.10.260.40 3 80 8.2E-19 T 12-10-2018 TL08_06880 42026783c937826c422fc2e294b0c0c4 197 SUPERFAMILY SSF51182 28 180 6.21E-15 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_06880 42026783c937826c422fc2e294b0c0c4 197 SMART SM00530 17 72 2.5E-17 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 Pfam PF00067 Cytochrome P450 271 377 6.4E-18 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 SUPERFAMILY SSF48264 23 408 4.32E-87 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00359 B-class P450 signature 199 221 1.7E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00359 B-class P450 signature 357 368 1.7E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00359 B-class P450 signature 348 357 1.7E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00359 B-class P450 signature 281 292 1.7E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00359 B-class P450 signature 299 326 1.7E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00359 B-class P450 signature 144 160 1.7E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00359 B-class P450 signature 161 176 1.7E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00359 B-class P450 signature 327 342 1.7E-41 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 Gene3D G3DSA:1.10.630.10 16 408 3.1E-117 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00385 P450 superfamily signature 246 263 7.5E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00385 P450 superfamily signature 281 292 7.5E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00385 P450 superfamily signature 357 368 7.5E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16225 7366e2aa7bcb084a804f87876d2d2fb9 408 PRINTS PR00385 P450 superfamily signature 348 357 7.5E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07735 623d5a1830d3f85e2f3e6495446bb405 291 Pfam PF12697 Alpha/beta hydrolase family 54 271 1.5E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_07735 623d5a1830d3f85e2f3e6495446bb405 291 Gene3D G3DSA:3.40.50.1820 2 275 1.0E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07735 623d5a1830d3f85e2f3e6495446bb405 291 SUPERFAMILY SSF53474 22 271 2.54E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_02815 0acb508f0758baaa9280d1a767063c86 161 Pfam PF08592 Domain of unknown function (DUF1772) 18 153 2.6E-18 T 12-10-2018 TL08_02080 44cf50bde370264375cfa8d96e6c714b 66 SUPERFAMILY SSF54285 1 66 1.8E-15 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TL08_02080 44cf50bde370264375cfa8d96e6c714b 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 66 1.5E-17 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis TL08_02080 44cf50bde370264375cfa8d96e6c714b 66 Gene3D G3DSA:3.10.20.30 1 66 1.1E-20 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TL08_02080 44cf50bde370264375cfa8d96e6c714b 66 Pfam PF02597 ThiS family 3 66 1.0E-12 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TL08_05625 04bfa910ce5a3258d46f4922ff4fd15f 276 Pfam PF01814 Hemerythrin HHE cation binding domain 148 271 2.7E-17 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TL08_05625 04bfa910ce5a3258d46f4922ff4fd15f 276 Gene3D G3DSA:1.20.120.520 138 276 1.2E-21 T 12-10-2018 TL08_05625 04bfa910ce5a3258d46f4922ff4fd15f 276 Pfam PF04075 F420H(2)-dependent quinone reductase 10 134 3.9E-16 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_05625 04bfa910ce5a3258d46f4922ff4fd15f 276 Gene3D G3DSA:2.30.110.10 2 134 2.3E-27 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_02245 fbcaf9bcd0b73fd0ccc3df340e561434 386 Pfam PF06114 IrrE N-terminal-like domain 197 296 1.4E-17 T 12-10-2018 IPR010359 IrrE N-terminal-like domain TL08_02245 fbcaf9bcd0b73fd0ccc3df340e561434 386 SMART SM00530 17 72 0.0021 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_02245 fbcaf9bcd0b73fd0ccc3df340e561434 386 Gene3D G3DSA:1.10.260.40 9 81 6.5E-7 T 12-10-2018 TL08_02245 fbcaf9bcd0b73fd0ccc3df340e561434 386 SUPERFAMILY SSF47413 16 74 1.32E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_18340 5fc694a1525e8235d7d2a40d36b69449 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 2.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_18340 5fc694a1525e8235d7d2a40d36b69449 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 2.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_18340 5fc694a1525e8235d7d2a40d36b69449 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 2.5E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_18340 5fc694a1525e8235d7d2a40d36b69449 284 Pfam PF00561 alpha/beta hydrolase fold 26 147 1.7E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_18340 5fc694a1525e8235d7d2a40d36b69449 284 Gene3D G3DSA:3.40.50.1820 5 260 7.1E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18340 5fc694a1525e8235d7d2a40d36b69449 284 SUPERFAMILY SSF53474 24 259 1.13E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_26540 ccd31b5ddb62a6c996a489b1d3468ad3 334 Pfam PF01032 FecCD transport family 6 325 4.6E-94 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_26540 ccd31b5ddb62a6c996a489b1d3468ad3 334 SUPERFAMILY SSF81345 4 325 1.18E-82 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_26540 ccd31b5ddb62a6c996a489b1d3468ad3 334 Gene3D G3DSA:1.10.3470.10 1 331 4.0E-107 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_14265 e19a379ff1db880c5aca6feb83796ab8 159 SMART SM00347 38 140 8.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_14265 e19a379ff1db880c5aca6feb83796ab8 159 SUPERFAMILY SSF46785 21 151 2.94E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_14265 e19a379ff1db880c5aca6feb83796ab8 159 Pfam PF12802 MarR family 45 102 1.8E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_14265 e19a379ff1db880c5aca6feb83796ab8 159 Gene3D G3DSA:1.10.10.10 1 154 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07170 cf09c18c26cb009203a9ba72e1676b55 432 SUPERFAMILY SSF103473 11 406 3.27E-65 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_07170 cf09c18c26cb009203a9ba72e1676b55 432 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_07170 cf09c18c26cb009203a9ba72e1676b55 432 Gene3D G3DSA:1.20.1720.10 23 403 6.0E-105 T 12-10-2018 TL08_07170 cf09c18c26cb009203a9ba72e1676b55 432 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 21 394 1.2E-102 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 TL08_07170 cf09c18c26cb009203a9ba72e1676b55 432 Pfam PF07690 Major Facilitator Superfamily 30 371 1.3E-43 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_23245 20462a06fe66f9cccdb69d4be81f431d 256 Pfam PF00588 SpoU rRNA Methylase family 106 244 3.0E-30 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TL08_23245 20462a06fe66f9cccdb69d4be81f431d 256 SMART SM00967 13 90 2.6E-9 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TL08_23245 20462a06fe66f9cccdb69d4be81f431d 256 Gene3D G3DSA:3.30.1330.30 5 86 8.8E-8 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_23245 20462a06fe66f9cccdb69d4be81f431d 256 SUPERFAMILY SSF75217 88 254 3.09E-37 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TL08_23245 20462a06fe66f9cccdb69d4be81f431d 256 SUPERFAMILY SSF55315 8 84 3.77E-11 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TL08_23245 20462a06fe66f9cccdb69d4be81f431d 256 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 14 88 1.1E-12 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TL08_23245 20462a06fe66f9cccdb69d4be81f431d 256 Gene3D G3DSA:3.40.1280.10 88 251 8.3E-42 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TL08_24625 8732146a648db8aec1fdaa14f2bfa424 447 Pfam PF05977 Transmembrane secretion effector 10 414 3.4E-28 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_24625 8732146a648db8aec1fdaa14f2bfa424 447 SUPERFAMILY SSF103473 1 398 1.07E-44 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_24625 8732146a648db8aec1fdaa14f2bfa424 447 Gene3D G3DSA:1.20.1250.20 8 399 2.4E-35 T 12-10-2018 TL08_22795 dd1f04101a917ccae86302f261775a2a 321 SUPERFAMILY SSF53474 11 295 1.4E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_22795 dd1f04101a917ccae86302f261775a2a 321 Gene3D G3DSA:3.40.50.1820 7 300 8.9E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_22795 dd1f04101a917ccae86302f261775a2a 321 Pfam PF00561 alpha/beta hydrolase fold 24 129 5.2E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_22365 babc0c0e22b1130e2eb1fc3c9c7230a7 553 PIRSF PIRSF001294 3 553 7.3E-198 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TL08_22365 babc0c0e22b1130e2eb1fc3c9c7230a7 553 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 553 30.784 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TL08_22365 babc0c0e22b1130e2eb1fc3c9c7230a7 553 Pfam PF03814 Potassium-transporting ATPase A subunit 13 552 1.8E-208 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TL08_22365 babc0c0e22b1130e2eb1fc3c9c7230a7 553 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 552 2.6E-187 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 SUPERFAMILY SSF51735 7 246 4.13E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.9E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 Gene3D G3DSA:3.40.50.720 1 246 1.8E-72 T 12-10-2018 TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 7.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 7.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 7.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_19505 be5301c8f54a6580ec8a853537ddc639 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 246 2.1E-52 T 12-10-2018 TL08_12470 317b6e89838faa976f3405531cdd4752 225 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 123 136 - T 12-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TL08_12470 317b6e89838faa976f3405531cdd4752 225 Gene3D G3DSA:3.20.20.70 1 209 4.2E-57 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_12470 317b6e89838faa976f3405531cdd4752 225 SUPERFAMILY SSF51569 2 200 2.56E-48 T 12-10-2018 TL08_12470 317b6e89838faa976f3405531cdd4752 225 Pfam PF01081 KDPG and KHG aldolase 5 183 4.7E-35 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TL08_02755 31dda4d97c4a1bffd64ddfd9d8b7702d 629 SUPERFAMILY SSF116734 481 609 5.45E-5 T 12-10-2018 TL08_02755 31dda4d97c4a1bffd64ddfd9d8b7702d 629 Gene3D G3DSA:3.40.50.150 116 349 4.8E-43 T 12-10-2018 TL08_02755 31dda4d97c4a1bffd64ddfd9d8b7702d 629 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 134 150 2.3E-12 T 12-10-2018 TL08_02755 31dda4d97c4a1bffd64ddfd9d8b7702d 629 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 218 230 2.3E-12 T 12-10-2018 TL08_02755 31dda4d97c4a1bffd64ddfd9d8b7702d 629 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 157 171 2.3E-12 T 12-10-2018 TL08_02755 31dda4d97c4a1bffd64ddfd9d8b7702d 629 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 252 276 2.3E-12 T 12-10-2018 TL08_02755 31dda4d97c4a1bffd64ddfd9d8b7702d 629 Pfam PF02384 N-6 DNA Methylase 118 304 1.2E-31 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TL08_02755 31dda4d97c4a1bffd64ddfd9d8b7702d 629 SUPERFAMILY SSF53335 114 334 1.64E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_02755 31dda4d97c4a1bffd64ddfd9d8b7702d 629 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 221 227 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TL08_19760 fd67be2d256d0d28f76c54f4652a88ea 323 SUPERFAMILY SSF53850 116 288 1.0E-15 T 12-10-2018 TL08_19760 fd67be2d256d0d28f76c54f4652a88ea 323 Gene3D G3DSA:3.40.190.290 113 294 2.2E-16 T 12-10-2018 TL08_19760 fd67be2d256d0d28f76c54f4652a88ea 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19760 fd67be2d256d0d28f76c54f4652a88ea 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19760 fd67be2d256d0d28f76c54f4652a88ea 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19760 fd67be2d256d0d28f76c54f4652a88ea 323 Pfam PF03466 LysR substrate binding domain 122 287 1.4E-16 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_19760 fd67be2d256d0d28f76c54f4652a88ea 323 Gene3D G3DSA:1.10.10.10 3 88 6.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19760 fd67be2d256d0d28f76c54f4652a88ea 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.0E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_19760 fd67be2d256d0d28f76c54f4652a88ea 323 SUPERFAMILY SSF46785 4 98 3.62E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_08775 de8a92a39375b7000fe0bfda7d1614bc 267 SUPERFAMILY SSF75217 2 241 2.88E-88 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TL08_08775 de8a92a39375b7000fe0bfda7d1614bc 267 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 227 1.5E-66 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TL08_08775 de8a92a39375b7000fe0bfda7d1614bc 267 Gene3D G3DSA:3.40.1280.10 1 169 2.5E-63 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TL08_08775 de8a92a39375b7000fe0bfda7d1614bc 267 Gene3D G3DSA:1.10.1270.20 170 260 1.9E-31 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TL08_08775 de8a92a39375b7000fe0bfda7d1614bc 267 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 267 103.572 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TL08_08775 de8a92a39375b7000fe0bfda7d1614bc 267 PIRSF PIRSF000386 1 255 5.3E-92 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TL08_08775 de8a92a39375b7000fe0bfda7d1614bc 267 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 2.6E-75 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TL08_24090 ac0a85a1a50868efbdb5f613d7aeeaee 89 Gene3D G3DSA:1.10.1200.10 6 80 1.4E-17 T 12-10-2018 IPR036736 ACP-like superfamily TL08_24090 ac0a85a1a50868efbdb5f613d7aeeaee 89 Pfam PF00550 Phosphopantetheine attachment site 11 71 7.8E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_24090 ac0a85a1a50868efbdb5f613d7aeeaee 89 SUPERFAMILY SSF47336 9 80 1.44E-14 T 12-10-2018 IPR036736 ACP-like superfamily TL08_24090 ac0a85a1a50868efbdb5f613d7aeeaee 89 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 39 72 0.004 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TL08_07150 2c9be0968c837f026cf4d326c3f227b6 1058 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 220 230 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_07150 2c9be0968c837f026cf4d326c3f227b6 1058 Gene3D G3DSA:3.40.50.200 154 449 3.7E-89 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_07150 2c9be0968c837f026cf4d326c3f227b6 1058 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 388 398 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_07150 2c9be0968c837f026cf4d326c3f227b6 1058 Pfam PF00082 Subtilase family 178 437 1.4E-56 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_07150 2c9be0968c837f026cf4d326c3f227b6 1058 PRINTS PR00723 Subtilisin serine protease family (S8) signature 216 229 2.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_07150 2c9be0968c837f026cf4d326c3f227b6 1058 PRINTS PR00723 Subtilisin serine protease family (S8) signature 387 403 2.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_07150 2c9be0968c837f026cf4d326c3f227b6 1058 PRINTS PR00723 Subtilisin serine protease family (S8) signature 178 197 2.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_07150 2c9be0968c837f026cf4d326c3f227b6 1058 SUPERFAMILY SSF52743 162 447 3.53E-79 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_04720 4824c2dc0278fa2455ea0cc378a98a1f 382 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 10 379 2.4E-83 T 12-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 TL08_21015 f0ff6879160a0519a169e49cbebd2b6c 142 Gene3D G3DSA:2.30.110.10 4 139 1.1E-29 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_21015 f0ff6879160a0519a169e49cbebd2b6c 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 133 7.3E-35 T 12-10-2018 IPR019920 F420-binding domain, putative TL08_21015 f0ff6879160a0519a169e49cbebd2b6c 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 91 1.6E-16 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_21015 f0ff6879160a0519a169e49cbebd2b6c 142 SUPERFAMILY SSF50475 3 133 3.75E-28 T 12-10-2018 TL08_06725 ebc62faf3ee708d3def9200bed2eea89 218 SUPERFAMILY SSF64288 35 188 1.02E-16 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_06725 ebc62faf3ee708d3def9200bed2eea89 218 Gene3D G3DSA:3.40.1410.10 33 192 3.2E-29 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_07810 30c05aa552e8ff31ba20b7a30ef5582c 506 SUPERFAMILY SSF53474 71 475 9.28E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07810 30c05aa552e8ff31ba20b7a30ef5582c 506 Pfam PF00561 alpha/beta hydrolase fold 94 475 6.8E-28 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_25135 be2ac220521f3a01ce9ef988abcaec10 217 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 37 123 3.4E-20 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_25135 be2ac220521f3a01ce9ef988abcaec10 217 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 6 217 9.8E-74 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_25135 be2ac220521f3a01ce9ef988abcaec10 217 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 14 217 36.078 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_25135 be2ac220521f3a01ce9ef988abcaec10 217 PIRSF PIRSF000190 2 217 1.0E-74 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_25135 be2ac220521f3a01ce9ef988abcaec10 217 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 177 217 6.7E-18 T 12-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_25135 be2ac220521f3a01ce9ef988abcaec10 217 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 187 200 - T 12-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_25135 be2ac220521f3a01ce9ef988abcaec10 217 SUPERFAMILY SSF50475 16 217 9.62E-63 T 12-10-2018 TL08_25135 be2ac220521f3a01ce9ef988abcaec10 217 Gene3D G3DSA:2.30.110.10 14 216 6.6E-76 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_16220 cbce1c698c3ffc59a51fd3f8f55a30e9 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 3.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16220 cbce1c698c3ffc59a51fd3f8f55a30e9 224 SUPERFAMILY SSF46689 12 93 3.13E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16220 cbce1c698c3ffc59a51fd3f8f55a30e9 224 Gene3D G3DSA:1.10.357.10 22 217 5.0E-33 T 12-10-2018 TL08_07945 38743ed728fd71d295c370b50622b0db 253 Pfam PF04029 2-phosphosulpholactate phosphatase 28 244 7.6E-22 T 12-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TL08_07945 38743ed728fd71d295c370b50622b0db 253 Gene3D G3DSA:3.90.1560.10 23 250 4.8E-39 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TL08_07945 38743ed728fd71d295c370b50622b0db 253 SUPERFAMILY SSF142823 13 247 1.44E-43 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TL08_02875 b4d18617706f078d634d083770740f71 135 Gene3D G3DSA:1.20.5.1030 76 133 2.7E-17 T 12-10-2018 IPR038379 SecE superfamily TL08_02875 b4d18617706f078d634d083770740f71 135 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 81 135 1.5E-20 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 TL08_02875 b4d18617706f078d634d083770740f71 135 Hamap MF_00422 Protein translocase subunit SecE [secE]. 77 132 12.757 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_02875 b4d18617706f078d634d083770740f71 135 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 81 133 5.6E-19 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_02875 b4d18617706f078d634d083770740f71 135 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 82 110 - T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TL08_12220 7a4df77f215a4a32bef3bad955f2eeb1 346 Gene3D G3DSA:3.40.50.720 2 323 1.5E-45 T 12-10-2018 TL08_12220 7a4df77f215a4a32bef3bad955f2eeb1 346 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 230 6.9E-21 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_12220 7a4df77f215a4a32bef3bad955f2eeb1 346 SUPERFAMILY SSF51735 7 318 4.55E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_04540 fd91912b32af8c7ef73899b63201744e 152 SUPERFAMILY SSF55961 5 148 1.08E-16 T 12-10-2018 TL08_04540 fd91912b32af8c7ef73899b63201744e 152 Gene3D G3DSA:3.30.530.20 5 149 2.9E-13 T 12-10-2018 IPR023393 START-like domain superfamily TL08_04540 fd91912b32af8c7ef73899b63201744e 152 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 145 8.3E-10 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase TL08_01195 642116f65956d20a4b73ef9fe0154c5e 320 Gene3D G3DSA:3.60.21.10 45 257 1.1E-13 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_01195 642116f65956d20a4b73ef9fe0154c5e 320 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 47 234 9.0E-10 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TL08_01195 642116f65956d20a4b73ef9fe0154c5e 320 SUPERFAMILY SSF56300 43 284 2.44E-27 T 12-10-2018 TL08_14895 79f23d51ff46a5f2e718bf8fc77be2cb 344 SUPERFAMILY SSF51679 1 336 3.79E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_14895 79f23d51ff46a5f2e718bf8fc77be2cb 344 Gene3D G3DSA:3.20.20.30 1 337 2.4E-96 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_14895 79f23d51ff46a5f2e718bf8fc77be2cb 344 Pfam PF00296 Luciferase-like monooxygenase 5 313 3.7E-49 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_14895 79f23d51ff46a5f2e718bf8fc77be2cb 344 TIGRFAM TIGR04020 seco_metab_LLM: natural product biosynthesis luciferase-like monooxygenase domain 3 337 1.8E-132 T 12-10-2018 IPR024011 Natural product biosynthesis luciferase-like monooxygenase domain TL08_26660 c846429faea5ffcd834c4e4e06ecae69 140 SUPERFAMILY SSF54593 6 124 2.95E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_26660 c846429faea5ffcd834c4e4e06ecae69 140 Gene3D G3DSA:3.30.720.110 70 125 5.6E-25 T 12-10-2018 TL08_26660 c846429faea5ffcd834c4e4e06ecae69 140 Gene3D G3DSA:3.30.720.120 2 55 5.2E-24 T 12-10-2018 TL08_26660 c846429faea5ffcd834c4e4e06ecae69 140 Pfam PF12681 Glyoxalase-like domain 7 123 3.1E-7 T 12-10-2018 IPR025870 Glyoxalase-like domain TL08_21225 39eca26a937a46cb71266f4ffa5ab321 259 SUPERFAMILY SSF53335 13 257 8.75E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_21225 39eca26a937a46cb71266f4ffa5ab321 259 Gene3D G3DSA:3.40.50.150 11 255 1.3E-75 T 12-10-2018 TL08_21225 39eca26a937a46cb71266f4ffa5ab321 259 Gene3D G3DSA:1.10.150.290 132 238 1.3E-75 T 12-10-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 TL08_21225 39eca26a937a46cb71266f4ffa5ab321 259 Pfam PF13489 Methyltransferase domain 17 184 1.4E-14 T 12-10-2018 TL08_03210 d9a23eb65f00c8669f69b0d17d6ab020 202 Pfam PF03458 UPF0126 domain 90 159 2.9E-17 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 TL08_03210 d9a23eb65f00c8669f69b0d17d6ab020 202 Pfam PF03458 UPF0126 domain 4 78 9.2E-22 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 TL08_17595 c0b71b562f454eaec57df759e647cbd1 62 Pfam PF04149 Domain of unknown function (DUF397) 7 57 2.6E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_20080 8024caada9fadc1817b21a986ebf3ebf 75 Gene3D G3DSA:3.10.290.10 1 72 1.3E-21 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TL08_20080 8024caada9fadc1817b21a986ebf3ebf 75 SUPERFAMILY SSF55174 4 67 4.32E-18 T 12-10-2018 TL08_20080 8024caada9fadc1817b21a986ebf3ebf 75 Pfam PF13275 S4 domain 7 67 2.6E-24 T 12-10-2018 TL08_17085 4001cc0abab5bb9b9698a794fe846ca1 137 Pfam PF03259 Roadblock/LC7 domain 12 100 3.8E-21 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TL08_17085 4001cc0abab5bb9b9698a794fe846ca1 137 Gene3D G3DSA:3.30.450.30 6 132 5.0E-39 T 12-10-2018 TL08_17085 4001cc0abab5bb9b9698a794fe846ca1 137 SMART SM00960 10 101 2.2E-21 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TL08_17085 4001cc0abab5bb9b9698a794fe846ca1 137 SUPERFAMILY SSF103196 4 129 9.16E-27 T 12-10-2018 TL08_19050 74705b977918f0553cb5649c99686517 575 Pfam PF10592 AIPR protein 259 441 4.5E-45 T 12-10-2018 IPR018891 Abortive bacteriophage infection, resistance TL08_16265 b301bc4a5457c570fdaa7d5319be7a65 263 Pfam PF01614 Bacterial transcriptional regulator 124 245 2.2E-28 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_16265 b301bc4a5457c570fdaa7d5319be7a65 263 Gene3D G3DSA:3.30.450.40 82 251 1.9E-53 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_16265 b301bc4a5457c570fdaa7d5319be7a65 263 Pfam PF09339 IclR helix-turn-helix domain 12 62 8.7E-17 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_16265 b301bc4a5457c570fdaa7d5319be7a65 263 SUPERFAMILY SSF55781 67 249 6.28E-48 T 12-10-2018 TL08_16265 b301bc4a5457c570fdaa7d5319be7a65 263 Gene3D G3DSA:1.10.10.10 9 81 8.1E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16265 b301bc4a5457c570fdaa7d5319be7a65 263 SUPERFAMILY SSF46785 10 79 3.16E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16265 b301bc4a5457c570fdaa7d5319be7a65 263 SMART SM00346 10 97 3.7E-21 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_11040 b221ef4970bf7d99cacdf153475e27a0 320 Gene3D G3DSA:3.40.50.2000 10 97 1.6E-8 T 12-10-2018 TL08_11040 b221ef4970bf7d99cacdf153475e27a0 320 SUPERFAMILY SSF53756 9 311 5.49E-59 T 12-10-2018 TL08_11040 b221ef4970bf7d99cacdf153475e27a0 320 Gene3D G3DSA:3.40.50.2000 148 313 1.2E-37 T 12-10-2018 TL08_11040 b221ef4970bf7d99cacdf153475e27a0 320 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 155 266 2.0E-26 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TL08_11410 142fb5bc29acd0cdfb717da3386cd880 215 Pfam PF01478 Type IV leader peptidase family 77 185 1.4E-11 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TL08_01325 cbb53da2d948b0bf343cf7b313ca8c99 418 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 21 389 1.0E-104 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TL08_01325 cbb53da2d948b0bf343cf7b313ca8c99 418 Gene3D G3DSA:1.20.1530.10 17 399 4.6E-135 T 12-10-2018 IPR023171 Na/H antiporter domain superfamily TL08_01325 cbb53da2d948b0bf343cf7b313ca8c99 418 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 18 400 20.82 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TL08_01325 cbb53da2d948b0bf343cf7b313ca8c99 418 Pfam PF06965 Na+/H+ antiporter 1 20 391 2.9E-134 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TL08_08895 db2cc964f434474ebe15ca0a1290fabb 258 Gene3D G3DSA:3.40.50.150 22 253 4.0E-29 T 12-10-2018 TL08_08895 db2cc964f434474ebe15ca0a1290fabb 258 Pfam PF08241 Methyltransferase domain 69 163 1.2E-16 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_08895 db2cc964f434474ebe15ca0a1290fabb 258 SUPERFAMILY SSF53335 35 214 7.77E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13890 127887ce6dd5e8d28038e45c17178e68 387 Pfam PF13280 WYL domain 133 308 1.7E-23 T 12-10-2018 IPR026881 WYL domain TL08_13890 127887ce6dd5e8d28038e45c17178e68 387 Pfam PF08279 HTH domain 3 55 9.5E-11 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TL08_13890 127887ce6dd5e8d28038e45c17178e68 387 Gene3D G3DSA:1.10.10.10 1 57 1.1E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_13890 127887ce6dd5e8d28038e45c17178e68 387 SUPERFAMILY SSF46785 2 53 2.48E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_04255 d758cdca85dcc36d352261bdc5039200 187 Pfam PF00583 Acetyltransferase (GNAT) family 108 165 2.0E-4 T 12-10-2018 IPR000182 GNAT domain TL08_04255 d758cdca85dcc36d352261bdc5039200 187 Gene3D G3DSA:3.40.630.30 2 186 7.0E-29 T 12-10-2018 TL08_04255 d758cdca85dcc36d352261bdc5039200 187 SUPERFAMILY SSF55729 2 174 1.61E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_07430 a1a32cf5f3bbc2a7577166cd37c1d48a 527 Gene3D G3DSA:3.40.605.10 45 491 2.0E-116 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_07430 a1a32cf5f3bbc2a7577166cd37c1d48a 527 SUPERFAMILY SSF53720 40 498 1.07E-109 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_07430 a1a32cf5f3bbc2a7577166cd37c1d48a 527 Pfam PF00171 Aldehyde dehydrogenase family 43 493 7.7E-107 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_07430 a1a32cf5f3bbc2a7577166cd37c1d48a 527 Gene3D G3DSA:3.40.309.10 276 462 2.0E-116 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_07430 a1a32cf5f3bbc2a7577166cd37c1d48a 527 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 272 279 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TL08_12370 5f721377ab05c080621cef8288619c04 639 SMART SM00382 420 606 2.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12370 5f721377ab05c080621cef8288619c04 639 SUPERFAMILY SSF52540 387 629 1.18E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12370 5f721377ab05c080621cef8288619c04 639 Pfam PF00664 ABC transporter transmembrane region 84 352 1.7E-31 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_12370 5f721377ab05c080621cef8288619c04 639 SUPERFAMILY SSF90123 79 384 9.81E-54 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_12370 5f721377ab05c080621cef8288619c04 639 Pfam PF00005 ABC transporter 411 559 5.5E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12370 5f721377ab05c080621cef8288619c04 639 Gene3D G3DSA:3.40.50.300 391 639 1.8E-63 T 12-10-2018 TL08_12370 5f721377ab05c080621cef8288619c04 639 Gene3D G3DSA:1.20.1560.10 45 384 1.3E-51 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_09255 f537d1c5fb8ecb60fbc296564f792873 376 SUPERFAMILY SSF46894 287 373 3.68E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_09255 f537d1c5fb8ecb60fbc296564f792873 376 SMART SM00862 302 371 7.2E-12 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_09255 f537d1c5fb8ecb60fbc296564f792873 376 SUPERFAMILY SSF69618 17 274 1.96E-53 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_09255 f537d1c5fb8ecb60fbc296564f792873 376 Gene3D G3DSA:1.10.10.10 282 374 5.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_09255 f537d1c5fb8ecb60fbc296564f792873 376 Gene3D G3DSA:3.40.50.10090 48 184 7.2E-65 T 12-10-2018 TL08_09255 f537d1c5fb8ecb60fbc296564f792873 376 Pfam PF02602 Uroporphyrinogen-III synthase HemD 29 270 3.2E-39 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TL08_09255 f537d1c5fb8ecb60fbc296564f792873 376 Gene3D G3DSA:3.40.50.10090 22 269 7.2E-65 T 12-10-2018 TL08_09255 f537d1c5fb8ecb60fbc296564f792873 376 Pfam PF00486 Transcriptional regulatory protein, C terminal 312 371 1.0E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_09870 01c39a6c5745836cb4387f448ae7b249 388 Gene3D G3DSA:1.10.600.10 27 388 1.0E-108 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_09870 01c39a6c5745836cb4387f448ae7b249 388 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 262 274 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TL08_09870 01c39a6c5745836cb4387f448ae7b249 388 Pfam PF00348 Polyprenyl synthetase 66 307 5.3E-51 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TL08_09870 01c39a6c5745836cb4387f448ae7b249 388 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 118 132 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TL08_09870 01c39a6c5745836cb4387f448ae7b249 388 SUPERFAMILY SSF48576 40 387 1.98E-70 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 Gene3D G3DSA:3.40.50.12740 3 215 6.1E-64 T 12-10-2018 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 5.1E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 Pfam PF00072 Response regulator receiver domain 5 119 5.6E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.0E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 SUPERFAMILY SSF46894 145 214 2.11E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 SMART SM00421 152 209 8.4E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 SMART SM00448 3 118 1.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_26245 6882e8dbc0dbdd6dfb2a9f6d8169cda9 218 SUPERFAMILY SSF52172 1 134 5.41E-31 T 12-10-2018 IPR011006 CheY-like superfamily TL08_03225 c085b18960323f35db14716ad06aca65 364 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 177 194 - T 12-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TL08_03225 c085b18960323f35db14716ad06aca65 364 SUPERFAMILY SSF54197 39 202 3.59E-52 T 12-10-2018 IPR036265 HIT-like superfamily TL08_03225 c085b18960323f35db14716ad06aca65 364 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 42 363 6.8E-46 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TL08_03225 c085b18960323f35db14716ad06aca65 364 Gene3D G3DSA:3.30.428.10 42 361 4.1E-92 T 12-10-2018 IPR036265 HIT-like superfamily TL08_03225 c085b18960323f35db14716ad06aca65 364 SUPERFAMILY SSF54197 206 363 2.89E-32 T 12-10-2018 IPR036265 HIT-like superfamily TL08_03225 c085b18960323f35db14716ad06aca65 364 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 214 324 1.8E-16 T 12-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TL08_03225 c085b18960323f35db14716ad06aca65 364 PIRSF PIRSF000808 34 364 4.8E-105 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TL08_03225 c085b18960323f35db14716ad06aca65 364 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 40 201 2.3E-41 T 12-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TL08_03225 c085b18960323f35db14716ad06aca65 364 Gene3D G3DSA:3.30.428.10 71 201 4.1E-92 T 12-10-2018 IPR036265 HIT-like superfamily TL08_15060 cc879d18ff5a1d3c3f960d3e4de235c7 175 Gene3D G3DSA:1.10.238.10 4 173 2.5E-23 T 12-10-2018 TL08_15060 cc879d18ff5a1d3c3f960d3e4de235c7 175 ProSitePatterns PS00018 EF-hand calcium-binding domain. 17 29 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site TL08_15060 cc879d18ff5a1d3c3f960d3e4de235c7 175 ProSitePatterns PS00018 EF-hand calcium-binding domain. 67 79 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site TL08_15060 cc879d18ff5a1d3c3f960d3e4de235c7 175 Pfam PF13499 EF-hand domain pair 7 81 1.6E-8 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 TL08_15060 cc879d18ff5a1d3c3f960d3e4de235c7 175 SMART SM00054 95 124 110.0 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 TL08_15060 cc879d18ff5a1d3c3f960d3e4de235c7 175 SMART SM00054 8 36 2.7 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 TL08_15060 cc879d18ff5a1d3c3f960d3e4de235c7 175 SMART SM00054 58 86 6.5 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 TL08_15060 cc879d18ff5a1d3c3f960d3e4de235c7 175 SUPERFAMILY SSF47473 4 165 3.41E-22 T 12-10-2018 IPR011992 EF-hand domain pair TL08_25610 3940490e1e9fb145b5274c67fa6b3911 449 SUPERFAMILY SSF53383 11 416 9.11E-78 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_25610 3940490e1e9fb145b5274c67fa6b3911 449 Gene3D G3DSA:3.90.1150.10 19 412 4.8E-113 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_25610 3940490e1e9fb145b5274c67fa6b3911 449 Gene3D G3DSA:3.40.640.10 80 320 4.8E-113 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_25610 3940490e1e9fb145b5274c67fa6b3911 449 Pfam PF00202 Aminotransferase class-III 45 347 1.0E-36 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_13670 bd098c0362c5952e72dc50cd55b5e791 687 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 39 567 2.0E-115 T 12-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 TL08_13670 bd098c0362c5952e72dc50cd55b5e791 687 SUPERFAMILY SSF48208 70 392 1.81E-18 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_00155 9726f0e70f34501652685a04059c116b 396 SMART SM00240 322 372 9.5E-12 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TL08_00155 9726f0e70f34501652685a04059c116b 396 Pfam PF00498 FHA domain 324 386 1.7E-15 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TL08_00155 9726f0e70f34501652685a04059c116b 396 SUPERFAMILY SSF49879 264 393 1.38E-28 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 TL08_00155 9726f0e70f34501652685a04059c116b 396 Gene3D G3DSA:3.30.2320.60 1 128 1.5E-50 T 12-10-2018 TL08_00155 9726f0e70f34501652685a04059c116b 396 Gene3D G3DSA:2.60.200.20 279 395 1.3E-26 T 12-10-2018 TL08_00155 9726f0e70f34501652685a04059c116b 396 Pfam PF12401 Protein of unknown function (DUF2662) 4 117 1.7E-42 T 12-10-2018 IPR022128 Domain of unknown function DUF3662 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 3.6E-14 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 3.6E-14 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 3.6E-14 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 Pfam PF00117 Glutamine amidotransferase class-I 5 185 1.4E-53 T 12-10-2018 IPR017926 Glutamine amidotransferase TL08_00105 7b86568c870598f75c13fe2b4569a092 213 Gene3D G3DSA:3.40.50.880 1 193 3.5E-63 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00097 Anthranilate synthase component II signature 46 55 1.1E-35 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.1E-35 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.1E-35 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.1E-35 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.1E-35 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.1E-35 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 SUPERFAMILY SSF52317 1 188 4.44E-57 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.3E-7 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 2.3E-7 T 12-10-2018 TL08_00105 7b86568c870598f75c13fe2b4569a092 213 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 185 4.9E-68 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TL08_01285 e73a751bb6f9455834ed90fe24e1fc9a 224 SUPERFAMILY SSF51206 4 142 9.95E-37 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like TL08_01285 e73a751bb6f9455834ed90fe24e1fc9a 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.0E-18 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TL08_01285 e73a751bb6f9455834ed90fe24e1fc9a 224 SUPERFAMILY SSF46785 145 223 4.21E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_01285 e73a751bb6f9455834ed90fe24e1fc9a 224 Gene3D G3DSA:2.60.120.10 1 146 1.4E-46 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_01285 e73a751bb6f9455834ed90fe24e1fc9a 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 115 4.0E-24 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TL08_01285 e73a751bb6f9455834ed90fe24e1fc9a 224 SMART SM00419 167 215 2.2E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TL08_01285 e73a751bb6f9455834ed90fe24e1fc9a 224 SMART SM00100 10 128 3.2E-26 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TL08_01285 e73a751bb6f9455834ed90fe24e1fc9a 224 Gene3D G3DSA:1.10.10.10 147 224 2.7E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11975 fd372c3ca47aebbef9152090b703d998 344 SUPERFAMILY SSF51556 11 335 6.45E-75 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_11975 fd372c3ca47aebbef9152090b703d998 344 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 15 330 2.0E-83 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 TL08_11975 fd372c3ca47aebbef9152090b703d998 344 Gene3D G3DSA:3.20.20.140 2 343 3.7E-93 T 12-10-2018 TL08_11975 fd372c3ca47aebbef9152090b703d998 344 Pfam PF00962 Adenosine/AMP deaminase 15 328 1.5E-69 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 TL08_21980 277b08b1b58fdb42be05c6f26b27918e 447 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 8.0E-25 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TL08_21980 277b08b1b58fdb42be05c6f26b27918e 447 SUPERFAMILY SSF54368 8 105 1.01E-28 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_21980 277b08b1b58fdb42be05c6f26b27918e 447 Gene3D G3DSA:3.10.20.70 2 108 1.3E-33 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_21980 277b08b1b58fdb42be05c6f26b27918e 447 Pfam PF00120 Glutamine synthetase, catalytic domain 107 442 4.9E-125 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_21980 277b08b1b58fdb42be05c6f26b27918e 447 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TL08_21980 277b08b1b58fdb42be05c6f26b27918e 447 SUPERFAMILY SSF55931 108 444 1.28E-117 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TL08_21980 277b08b1b58fdb42be05c6f26b27918e 447 SMART SM01230 106 357 6.0E-126 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TL08_21980 277b08b1b58fdb42be05c6f26b27918e 447 Gene3D G3DSA:3.30.590.10 109 445 3.0E-120 T 12-10-2018 TL08_19430 c245f7cb6f5497c69962afd3e645fc89 246 Gene3D G3DSA:2.20.25.570 140 204 4.5E-37 T 12-10-2018 TL08_19430 c245f7cb6f5497c69962afd3e645fc89 246 Gene3D G3DSA:3.40.50.150 37 236 4.5E-37 T 12-10-2018 TL08_19430 c245f7cb6f5497c69962afd3e645fc89 246 SUPERFAMILY SSF53335 10 232 4.63E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_19430 c245f7cb6f5497c69962afd3e645fc89 246 Pfam PF13649 Methyltransferase domain 40 132 2.6E-15 T 12-10-2018 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 SUPERFAMILY SSF52172 3 133 2.85E-31 T 12-10-2018 IPR011006 CheY-like superfamily TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 SUPERFAMILY SSF46894 136 207 1.33E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 SMART SM00448 3 116 2.8E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 Pfam PF00072 Response regulator receiver domain 5 117 1.1E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 Gene3D G3DSA:3.40.50.12740 3 208 3.5E-62 T 12-10-2018 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 SMART SM00421 147 204 3.1E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 4.2E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_00590 fa129ff9cef93b5aa8dc261f1499e808 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_12850 a4dda5288acfeecaea22f2a465cf9f74 170 SUPERFAMILY SSF160904 4 158 1.96E-31 T 12-10-2018 TL08_12850 a4dda5288acfeecaea22f2a465cf9f74 170 Pfam PF11706 CGNR zinc finger 117 158 4.8E-15 T 12-10-2018 IPR021005 Zinc finger, CGNR TL08_12850 a4dda5288acfeecaea22f2a465cf9f74 170 Gene3D G3DSA:1.10.3300.10 1 160 5.0E-40 T 12-10-2018 IPR023286 ABATE domain superfamily TL08_12760 5ba8232ad840368638e1bd359f091069 452 PIRSF PIRSF000337 1 451 7.7E-143 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 TL08_12760 5ba8232ad840368638e1bd359f091069 452 Gene3D G3DSA:3.20.20.30 1 452 9.2E-128 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_12760 5ba8232ad840368638e1bd359f091069 452 Pfam PF00296 Luciferase-like monooxygenase 26 393 8.9E-54 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_12760 5ba8232ad840368638e1bd359f091069 452 SUPERFAMILY SSF51679 5 445 7.66E-112 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_12760 5ba8232ad840368638e1bd359f091069 452 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 16 439 4.9E-127 T 12-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 Pfam PF00384 Molybdopterin oxidoreductase 60 486 3.0E-70 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 SUPERFAMILY SSF50692 541 689 1.45E-40 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 Pfam PF01568 Molydopterin dinucleotide binding domain 579 686 3.1E-26 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 SMART SM00926 5 57 1.4E-5 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 Gene3D G3DSA:3.40.50.740 69 536 3.7E-152 T 12-10-2018 TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 Gene3D G3DSA:2.40.40.20 569 691 3.8E-38 T 12-10-2018 TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 SUPERFAMILY SSF53706 7 565 4.32E-160 T 12-10-2018 TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 7 50 9.4E-7 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 Gene3D G3DSA:3.40.228.10 140 339 3.7E-152 T 12-10-2018 TL08_09280 4e52452ce2f8a05423e711dc8582b4e1 701 Gene3D G3DSA:2.20.25.90 6 53 1.3E-8 T 12-10-2018 TL08_16380 6a18e1e9e35a22a9561303fdb4d09f73 312 Gene3D G3DSA:1.10.10.10 204 280 8.1E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16380 6a18e1e9e35a22a9561303fdb4d09f73 312 SUPERFAMILY SSF46785 207 281 4.18E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_01390 944f873e76f631f0d92e2e5d7db58d3f 263 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 138 158 - T 12-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site TL08_01390 944f873e76f631f0d92e2e5d7db58d3f 263 Pfam PF00795 Carbon-nitrogen hydrolase 2 253 1.1E-31 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TL08_01390 944f873e76f631f0d92e2e5d7db58d3f 263 SUPERFAMILY SSF56317 1 261 6.41E-61 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TL08_01390 944f873e76f631f0d92e2e5d7db58d3f 263 Gene3D G3DSA:3.60.110.10 1 263 1.7E-66 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TL08_17610 fc55f6bbaf55fad401fb55a4b1632393 303 Pfam PF00296 Luciferase-like monooxygenase 12 275 7.5E-43 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_17610 fc55f6bbaf55fad401fb55a4b1632393 303 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 17 279 1.3E-95 T 12-10-2018 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted TL08_17610 fc55f6bbaf55fad401fb55a4b1632393 303 SUPERFAMILY SSF51679 1 296 8.64E-52 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_17610 fc55f6bbaf55fad401fb55a4b1632393 303 Gene3D G3DSA:3.20.20.30 1 298 6.0E-52 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_21440 bc0cd53fda8be000bf7273ac602e2c30 366 Gene3D G3DSA:3.40.190.10 179 333 1.9E-19 T 12-10-2018 TL08_21440 bc0cd53fda8be000bf7273ac602e2c30 366 Pfam PF13379 NMT1-like family 47 282 8.3E-27 T 12-10-2018 TL08_21440 bc0cd53fda8be000bf7273ac602e2c30 366 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 51 344 5.1E-51 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 TL08_21440 bc0cd53fda8be000bf7273ac602e2c30 366 Gene3D G3DSA:3.40.190.10 47 178 1.5E-13 T 12-10-2018 TL08_21440 bc0cd53fda8be000bf7273ac602e2c30 366 SUPERFAMILY SSF53850 49 276 2.59E-34 T 12-10-2018 TL08_08880 6a7445f07467ffd535a281542e45df29 253 Gene3D G3DSA:3.40.1160.10 2 247 5.2E-77 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TL08_08880 6a7445f07467ffd535a281542e45df29 253 Hamap MF_01220_B Uridylate kinase [pyrH]. 9 242 42.657 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TL08_08880 6a7445f07467ffd535a281542e45df29 253 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 11 242 2.0E-87 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TL08_08880 6a7445f07467ffd535a281542e45df29 253 Pfam PF00696 Amino acid kinase family 13 221 1.6E-28 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TL08_08880 6a7445f07467ffd535a281542e45df29 253 PIRSF PIRSF005650 6 249 6.5E-86 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TL08_08880 6a7445f07467ffd535a281542e45df29 253 SUPERFAMILY SSF53633 11 241 5.24E-69 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 Gene3D G3DSA:1.10.8.280 182 294 2.2E-151 T 12-10-2018 TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 Gene3D G3DSA:3.40.50.300 43 473 2.2E-151 T 12-10-2018 TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 Gene3D G3DSA:1.20.1580.10 128 372 2.2E-151 T 12-10-2018 TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 ProSitePatterns PS00211 ABC transporters family signature. 372 386 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 ProSitePatterns PS00211 ABC transporters family signature. 680 694 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 Pfam PF00005 ABC transporter 504 707 2.2E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 SUPERFAMILY SSF52540 49 452 7.79E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 SUPERFAMILY SSF52540 499 762 1.33E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 Gene3D G3DSA:3.40.50.300 498 784 4.1E-100 T 12-10-2018 TL08_19355 c581c43ca5f1d9a51416c3eaf930b2b5 790 Gene3D G3DSA:1.20.1580.10 580 618 4.1E-100 T 12-10-2018 TL08_04110 c1f9b47ae9a9be25c9d24aeb1fec6da9 208 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 1 205 4.1E-57 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 TL08_04110 c1f9b47ae9a9be25c9d24aeb1fec6da9 208 Pfam PF03006 Haemolysin-III related 2 198 3.2E-40 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 TL08_15175 4c15a6c7314c4732ad068cd739e28b7b 527 SUPERFAMILY SSF52540 289 498 1.98E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_15175 4c15a6c7314c4732ad068cd739e28b7b 527 Pfam PF00005 ABC transporter 33 183 4.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_15175 4c15a6c7314c4732ad068cd739e28b7b 527 Pfam PF00005 ABC transporter 289 443 6.8E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_15175 4c15a6c7314c4732ad068cd739e28b7b 527 Gene3D G3DSA:3.40.50.300 284 510 2.0E-44 T 12-10-2018 TL08_15175 4c15a6c7314c4732ad068cd739e28b7b 527 ProSitePatterns PS00211 ABC transporters family signature. 416 430 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_15175 4c15a6c7314c4732ad068cd739e28b7b 527 SUPERFAMILY SSF52540 17 241 6.45E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_15175 4c15a6c7314c4732ad068cd739e28b7b 527 SMART SM00382 42 239 1.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_15175 4c15a6c7314c4732ad068cd739e28b7b 527 SMART SM00382 298 492 7.0E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_15175 4c15a6c7314c4732ad068cd739e28b7b 527 Gene3D G3DSA:3.40.50.300 14 248 4.7E-55 T 12-10-2018 TL08_02285 7c0b2a5852109ac6b4c4f974d965d862 172 Gene3D G3DSA:3.30.1460.10 42 145 4.2E-5 T 12-10-2018 TL08_02285 7c0b2a5852109ac6b4c4f974d965d862 172 Pfam PF10722 Putative bacterial sensory transduction regulator 14 134 2.2E-22 T 12-10-2018 IPR019660 Putative sensory transduction regulator YbjN TL08_02285 7c0b2a5852109ac6b4c4f974d965d862 172 SUPERFAMILY SSF69635 9 137 5.26E-28 T 12-10-2018 TL08_05385 273e4bba79c7a336c1d35c7701da8453 148 SUPERFAMILY SSF54427 12 145 2.09E-21 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_05385 273e4bba79c7a336c1d35c7701da8453 148 Gene3D G3DSA:3.10.450.50 9 147 3.0E-21 T 12-10-2018 TL08_05385 273e4bba79c7a336c1d35c7701da8453 148 Pfam PF12680 SnoaL-like domain 24 129 2.5E-9 T 12-10-2018 IPR037401 SnoaL-like domain TL08_09420 8f3ccbe019bc7ed470f89e613a8c1f5e 136 Pfam PF11239 Protein of unknown function (DUF3040) 1 85 1.1E-29 T 12-10-2018 IPR021401 Protein of unknown function DUF3040 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 PRINTS PR00783 Major intrinsic protein family signature 138 156 3.8E-35 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 PRINTS PR00783 Major intrinsic protein family signature 176 198 3.8E-35 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 PRINTS PR00783 Major intrinsic protein family signature 83 102 3.8E-35 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 PRINTS PR00783 Major intrinsic protein family signature 5 24 3.8E-35 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 PRINTS PR00783 Major intrinsic protein family signature 46 70 3.8E-35 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 PRINTS PR00783 Major intrinsic protein family signature 223 243 3.8E-35 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 ProSitePatterns PS00221 MIP family signature. 64 72 - T 12-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 Pfam PF00230 Major intrinsic protein 7 240 7.4E-40 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 Gene3D G3DSA:1.20.1080.10 3 244 6.4E-67 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TL08_23790 d295a440332e879fcca3ecb2a937cc46 245 SUPERFAMILY SSF81338 7 242 7.85E-59 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TL08_08910 9feb99bdf958c5794960d7121ec72a0a 93 Pfam PF10939 Protein of unknown function (DUF2631) 10 72 8.1E-28 T 12-10-2018 IPR024341 Protein of unknown function DUF2631 TL08_08910 9feb99bdf958c5794960d7121ec72a0a 93 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 14 88 7.0E-7 T 12-10-2018 IPR024341 Protein of unknown function DUF2631 TL08_04760 c109dbf0571e999857dffeabb165e5ff 575 SMART SM00490 314 395 1.1E-33 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_04760 c109dbf0571e999857dffeabb165e5ff 575 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 207 215 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TL08_04760 c109dbf0571e999857dffeabb165e5ff 575 Gene3D G3DSA:3.40.50.300 272 447 6.4E-48 T 12-10-2018 TL08_04760 c109dbf0571e999857dffeabb165e5ff 575 SUPERFAMILY SSF52540 129 413 4.89E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04760 c109dbf0571e999857dffeabb165e5ff 575 Pfam PF00271 Helicase conserved C-terminal domain 287 395 5.3E-29 T 12-10-2018 IPR001650 Helicase, C-terminal TL08_04760 c109dbf0571e999857dffeabb165e5ff 575 SMART SM00487 78 278 4.4E-55 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_04760 c109dbf0571e999857dffeabb165e5ff 575 Gene3D G3DSA:3.40.50.300 27 264 7.6E-73 T 12-10-2018 TL08_04760 c109dbf0571e999857dffeabb165e5ff 575 Pfam PF00270 DEAD/DEAH box helicase 84 244 1.1E-50 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TL08_19065 16a7613b5ba2d3daaa2fd47316e6d788 146 SUPERFAMILY SSF50475 12 144 4.09E-33 T 12-10-2018 TL08_19065 16a7613b5ba2d3daaa2fd47316e6d788 146 Gene3D G3DSA:2.30.110.10 7 145 2.9E-42 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_19065 16a7613b5ba2d3daaa2fd47316e6d788 146 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 12 92 1.2E-15 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_19065 16a7613b5ba2d3daaa2fd47316e6d788 146 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 12 142 2.2E-40 T 12-10-2018 IPR019920 F420-binding domain, putative TL08_18735 f584d63bd274f437f0b1ef3cbdcd11b9 1721 Pfam PF13086 AAA domain 363 427 2.9E-10 T 12-10-2018 TL08_18735 f584d63bd274f437f0b1ef3cbdcd11b9 1721 Gene3D G3DSA:3.40.50.300 329 575 2.8E-19 T 12-10-2018 TL08_18735 f584d63bd274f437f0b1ef3cbdcd11b9 1721 Gene3D G3DSA:3.40.50.300 898 1146 5.5E-8 T 12-10-2018 TL08_18735 f584d63bd274f437f0b1ef3cbdcd11b9 1721 Pfam PF04480 Protein of unknown function (DUF559) 1386 1465 3.1E-6 T 12-10-2018 IPR007569 Protein of unknown function DUF559 TL08_18735 f584d63bd274f437f0b1ef3cbdcd11b9 1721 SUPERFAMILY SSF52980 1365 1468 2.86E-15 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TL08_18735 f584d63bd274f437f0b1ef3cbdcd11b9 1721 Gene3D G3DSA:3.40.50.300 1156 1353 3.1E-24 T 12-10-2018 TL08_18735 f584d63bd274f437f0b1ef3cbdcd11b9 1721 Pfam PF13087 AAA domain 1135 1322 5.4E-12 T 12-10-2018 TL08_18735 f584d63bd274f437f0b1ef3cbdcd11b9 1721 Gene3D G3DSA:3.40.960.10 1371 1471 1.0E-17 T 12-10-2018 TL08_18735 f584d63bd274f437f0b1ef3cbdcd11b9 1721 SUPERFAMILY SSF52540 361 1322 2.38E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_11675 0976c3fac45ba15accc530275c134a36 253 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 244 3.1E-68 T 12-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 TL08_11675 0976c3fac45ba15accc530275c134a36 253 Gene3D G3DSA:3.40.50.1360 1 246 4.6E-86 T 12-10-2018 TL08_11675 0976c3fac45ba15accc530275c134a36 253 SUPERFAMILY SSF100950 5 246 1.02E-62 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_11675 0976c3fac45ba15accc530275c134a36 253 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 12 237 2.7E-73 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 TL08_11235 4c4a020af66faf54e8528d6c322831cb 330 Gene3D G3DSA:3.40.50.970 3 191 1.9E-77 T 12-10-2018 TL08_11235 4c4a020af66faf54e8528d6c322831cb 330 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 1.1E-43 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_11235 4c4a020af66faf54e8528d6c322831cb 330 SMART SM00861 4 179 6.6E-60 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_11235 4c4a020af66faf54e8528d6c322831cb 330 Pfam PF02780 Transketolase, C-terminal domain 193 314 6.4E-39 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TL08_11235 4c4a020af66faf54e8528d6c322831cb 330 SUPERFAMILY SSF52518 4 203 1.54E-67 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_11235 4c4a020af66faf54e8528d6c322831cb 330 Gene3D G3DSA:3.40.50.920 192 325 7.5E-45 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_11235 4c4a020af66faf54e8528d6c322831cb 330 SUPERFAMILY SSF52922 190 323 3.01E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_24215 9a39e3f580e53a1d55144a83a619fca6 65 Pfam PF04149 Domain of unknown function (DUF397) 9 60 6.0E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_05580 c2a8c0b63899a48d6175138dc9a83f0d 175 SUPERFAMILY SSF55729 6 165 6.28E-32 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_05580 c2a8c0b63899a48d6175138dc9a83f0d 175 Gene3D G3DSA:3.40.630.30 5 173 1.0E-47 T 12-10-2018 TL08_05580 c2a8c0b63899a48d6175138dc9a83f0d 175 Pfam PF13420 Acetyltransferase (GNAT) domain 7 157 1.6E-29 T 12-10-2018 TL08_22535 08985e4b1760a1c81c8b9d558b4da626 216 Gene3D G3DSA:3.40.470.10 1 216 3.6E-81 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_22535 08985e4b1760a1c81c8b9d558b4da626 216 Pfam PF03167 Uracil DNA glycosylase superfamily 46 202 2.7E-16 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_22535 08985e4b1760a1c81c8b9d558b4da626 216 SUPERFAMILY SSF52141 2 214 1.37E-70 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_22535 08985e4b1760a1c81c8b9d558b4da626 216 SMART SM00987 44 203 1.3E-30 T 12-10-2018 TL08_22535 08985e4b1760a1c81c8b9d558b4da626 216 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 52 61 - T 12-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_22535 08985e4b1760a1c81c8b9d558b4da626 216 SMART SM00986 44 203 1.3E-30 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_22535 08985e4b1760a1c81c8b9d558b4da626 216 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 2 214 33.256 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_13970 9da37cbd7882ebbed4f0df4df19336b2 229 Gene3D G3DSA:1.10.357.10 3 181 8.5E-40 T 12-10-2018 TL08_13970 9da37cbd7882ebbed4f0df4df19336b2 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 5.0E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_13970 9da37cbd7882ebbed4f0df4df19336b2 229 SUPERFAMILY SSF48498 83 174 7.79E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_13970 9da37cbd7882ebbed4f0df4df19336b2 229 SUPERFAMILY SSF46689 5 84 2.14E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_13970 9da37cbd7882ebbed4f0df4df19336b2 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_13970 9da37cbd7882ebbed4f0df4df19336b2 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_01270 3c15f7c2e4dd748e3e3e217a99dbede1 271 Pfam PF00753 Metallo-beta-lactamase superfamily 35 199 6.6E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_01270 3c15f7c2e4dd748e3e3e217a99dbede1 271 SUPERFAMILY SSF56281 24 270 6.16E-50 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_01270 3c15f7c2e4dd748e3e3e217a99dbede1 271 Gene3D G3DSA:3.60.15.10 14 203 1.1E-42 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_01270 3c15f7c2e4dd748e3e3e217a99dbede1 271 Gene3D G3DSA:1.10.10.10 207 271 1.7E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_01270 3c15f7c2e4dd748e3e3e217a99dbede1 271 SMART SM00849 37 199 3.6E-27 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_10805 43cf9881e9c515f2e518c0ede03b5538 445 Gene3D G3DSA:1.20.120.450 7 157 9.2E-8 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_10805 43cf9881e9c515f2e518c0ede03b5538 445 Gene3D G3DSA:3.90.1580.10 166 443 9.9E-63 T 12-10-2018 TL08_10805 43cf9881e9c515f2e518c0ede03b5538 445 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 439 51.573 T 12-10-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 TL08_10805 43cf9881e9c515f2e518c0ede03b5538 445 Pfam PF03781 Sulfatase-modifying factor enzyme 1 178 437 1.9E-64 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 TL08_10805 43cf9881e9c515f2e518c0ede03b5538 445 SUPERFAMILY SSF56436 179 439 5.42E-76 T 12-10-2018 IPR016187 C-type lectin fold TL08_10805 43cf9881e9c515f2e518c0ede03b5538 445 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 18 436 2.5E-133 T 12-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 TL08_10805 43cf9881e9c515f2e518c0ede03b5538 445 Pfam PF12867 DinB superfamily 21 151 2.9E-25 T 12-10-2018 IPR024775 DinB-like domain TL08_10805 43cf9881e9c515f2e518c0ede03b5538 445 SUPERFAMILY SSF109854 10 148 2.75E-19 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 364 373 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00359 B-class P450 signature 212 234 3.4E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00359 B-class P450 signature 294 305 3.4E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00359 B-class P450 signature 174 189 3.4E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00359 B-class P450 signature 341 356 3.4E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00359 B-class P450 signature 157 173 3.4E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00359 B-class P450 signature 110 121 3.4E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00359 B-class P450 signature 313 340 3.4E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00359 B-class P450 signature 362 371 3.4E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00359 B-class P450 signature 371 382 3.4E-47 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 SUPERFAMILY SSF48264 40 422 1.44E-88 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 Pfam PF00067 Cytochrome P450 228 391 3.2E-18 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00385 P450 superfamily signature 371 382 1.3E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00385 P450 superfamily signature 259 276 1.3E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00385 P450 superfamily signature 294 305 1.3E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 PRINTS PR00385 P450 superfamily signature 362 371 1.3E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18565 34415fd55826e59e4323fb32eb9fc9bc 422 Gene3D G3DSA:1.10.630.10 36 422 5.1E-119 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20235 b8eafc7fed3b5045d79584dd789cac77 425 SUPERFAMILY SSF56059 130 326 1.89E-26 T 12-10-2018 TL08_20235 b8eafc7fed3b5045d79584dd789cac77 425 Pfam PF13535 ATP-grasp domain 134 293 2.4E-7 T 12-10-2018 TL08_20235 b8eafc7fed3b5045d79584dd789cac77 425 Gene3D G3DSA:3.30.470.20 94 422 6.3E-27 T 12-10-2018 TL08_06905 c3cb26ce79afcec5ed03302fe4e5f301 466 SUPERFAMILY SSF51338 19 454 3.73E-21 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_06905 c3cb26ce79afcec5ed03302fe4e5f301 466 Gene3D G3DSA:3.20.20.140 82 446 5.0E-86 T 12-10-2018 TL08_06905 c3cb26ce79afcec5ed03302fe4e5f301 466 Pfam PF01979 Amidohydrolase family 77 432 3.2E-22 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_06905 c3cb26ce79afcec5ed03302fe4e5f301 466 Gene3D G3DSA:2.30.40.10 26 441 5.0E-86 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_06905 c3cb26ce79afcec5ed03302fe4e5f301 466 SUPERFAMILY SSF51556 80 387 4.25E-43 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_06635 da370379b79cff224479dc5a53d64646 431 Pfam PF00534 Glycosyl transferases group 1 211 374 1.8E-37 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_06635 da370379b79cff224479dc5a53d64646 431 SUPERFAMILY SSF53756 1 394 8.22E-96 T 12-10-2018 TL08_06635 da370379b79cff224479dc5a53d64646 431 Gene3D G3DSA:3.40.50.2000 195 377 1.5E-101 T 12-10-2018 TL08_06635 da370379b79cff224479dc5a53d64646 431 Gene3D G3DSA:3.40.50.2000 5 393 1.5E-101 T 12-10-2018 TL08_06635 da370379b79cff224479dc5a53d64646 431 Pfam PF13439 Glycosyltransferase Family 4 15 197 3.8E-34 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_04780 113750e31304b5483532009c3153fd00 348 SUPERFAMILY SSF53474 15 305 2.44E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_04780 113750e31304b5483532009c3153fd00 348 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 4.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_04780 113750e31304b5483532009c3153fd00 348 PRINTS PR00111 Alpha/beta hydrolase fold signature 68 83 4.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_04780 113750e31304b5483532009c3153fd00 348 PRINTS PR00111 Alpha/beta hydrolase fold signature 127 140 4.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_04780 113750e31304b5483532009c3153fd00 348 Gene3D G3DSA:3.40.50.1820 12 309 2.3E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_04780 113750e31304b5483532009c3153fd00 348 Pfam PF00561 alpha/beta hydrolase fold 46 296 3.4E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 Pfam PF00067 Cytochrome P450 31 418 2.9E-50 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 375 384 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00385 P450 superfamily signature 382 393 7.0E-10 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00385 P450 superfamily signature 301 312 7.0E-10 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00385 P450 superfamily signature 261 278 7.0E-10 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00385 P450 superfamily signature 373 382 7.0E-10 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 Gene3D G3DSA:1.10.630.10 13 430 1.8E-82 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00463 E-class P450 group I signature 148 166 1.3E-22 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00463 E-class P450 group I signature 341 365 1.3E-22 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00463 E-class P450 group I signature 382 405 1.3E-22 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00463 E-class P450 group I signature 38 57 1.3E-22 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00463 E-class P450 group I signature 250 267 1.3E-22 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00463 E-class P450 group I signature 300 318 1.3E-22 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00463 E-class P450 group I signature 270 296 1.3E-22 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 PRINTS PR00463 E-class P450 group I signature 372 382 1.3E-22 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_14630 c34ec982cf5e98e46d67ebb6d9be7ce5 435 SUPERFAMILY SSF48264 29 435 3.67E-78 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_03540 ec67ead866334d9f251895857acba61b 371 Pfam PF03990 Domain of unknown function (DUF348) 89 121 1.3E-5 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 TL08_03540 ec67ead866334d9f251895857acba61b 371 Pfam PF03990 Domain of unknown function (DUF348) 32 72 1.2E-12 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 TL08_03540 ec67ead866334d9f251895857acba61b 371 Pfam PF03990 Domain of unknown function (DUF348) 146 186 1.9E-9 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 TL08_03540 ec67ead866334d9f251895857acba61b 371 Gene3D G3DSA:2.20.230.10 198 284 8.7E-22 T 12-10-2018 TL08_03540 ec67ead866334d9f251895857acba61b 371 Pfam PF07501 G5 domain 204 277 1.1E-18 T 12-10-2018 IPR011098 G5 domain TL08_03540 ec67ead866334d9f251895857acba61b 371 Pfam PF06737 Transglycosylase-like domain 286 363 1.1E-25 T 12-10-2018 IPR010618 Transglycosylase-like TL08_03540 ec67ead866334d9f251895857acba61b 371 Gene3D G3DSA:1.10.530.10 288 369 3.0E-28 T 12-10-2018 TL08_03540 ec67ead866334d9f251895857acba61b 371 SMART SM01208 200 278 3.8E-20 T 12-10-2018 IPR011098 G5 domain TL08_03540 ec67ead866334d9f251895857acba61b 371 SUPERFAMILY SSF53955 286 369 1.26E-25 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 SUPERFAMILY SSF46894 152 211 6.12E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 Pfam PF00072 Response regulator receiver domain 8 120 1.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 202 8.1E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 Gene3D G3DSA:3.40.50.12740 6 211 2.3E-66 T 12-10-2018 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 SMART SM00421 148 205 1.8E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 SMART SM00448 6 119 2.0E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 4.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 4.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 4.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03490 daeb061cae88a3dd2a25b0d5f94242ce 218 SUPERFAMILY SSF52172 7 135 4.27E-34 T 12-10-2018 IPR011006 CheY-like superfamily TL08_08110 57520a5269f37775b7d3497a75052238 158 Pfam PF14017 Protein of unknown function (DUF4233) 44 146 1.1E-24 T 12-10-2018 IPR025327 Protein of unknown function DUF4233 TL08_09365 f7dab8740eed4d27d5fc083e867284ba 476 SUPERFAMILY SSF52540 1 388 5.81E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09365 f7dab8740eed4d27d5fc083e867284ba 476 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 33 387 3.8E-33 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_09365 f7dab8740eed4d27d5fc083e867284ba 476 Gene3D G3DSA:3.40.50.300 281 414 1.7E-6 T 12-10-2018 TL08_09365 f7dab8740eed4d27d5fc083e867284ba 476 Gene3D G3DSA:3.40.50.300 1 175 3.4E-5 T 12-10-2018 TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 SMART SM00710 196 226 760.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 SMART SM00710 172 194 1100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 SMART SM00710 293 315 6800.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 SMART SM00710 229 251 930.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 SMART SM00710 317 339 170.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 SMART SM00710 253 287 3900.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 Pfam PF13229 Right handed beta helix region 145 341 9.7E-10 T 12-10-2018 IPR039448 Right handed beta helix domain TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 Pfam PF07602 Protein of unknown function (DUF1565) 56 95 3.2E-5 T 12-10-2018 IPR011459 Domain of unknown function DUF1565 TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 Gene3D G3DSA:2.160.20.10 37 413 9.0E-97 T 12-10-2018 IPR012334 Pectin lyase fold TL08_12400 945e601c2d3a123596de610f6fc5a59d 415 SUPERFAMILY SSF51126 43 402 2.65E-60 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_05330 e1d3829e6d3d0979e85d44215b387a9e 133 SUPERFAMILY SSF55298 1 133 1.37E-26 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_05330 e1d3829e6d3d0979e85d44215b387a9e 133 Gene3D G3DSA:3.30.1330.40 3 133 3.9E-27 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_05330 e1d3829e6d3d0979e85d44215b387a9e 133 Pfam PF01042 Endoribonuclease L-PSP 18 131 6.6E-19 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TL08_23025 f0f70813f7cef054cfbfd4840916eb2f 391 SUPERFAMILY SSF56235 107 264 4.78E-13 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_23025 f0f70813f7cef054cfbfd4840916eb2f 391 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 162 365 9.5E-17 T 12-10-2018 IPR005079 Peptidase C45 TL08_23025 f0f70813f7cef054cfbfd4840916eb2f 391 Gene3D G3DSA:3.60.60.10 109 358 4.3E-25 T 12-10-2018 TL08_17040 e504d726a675dfed99910955bdeb2b0c 563 SUPERFAMILY SSF53850 68 556 7.96E-117 T 12-10-2018 TL08_17040 e504d726a675dfed99910955bdeb2b0c 563 PIRSF PIRSF002741 24 559 1.7E-89 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_17040 e504d726a675dfed99910955bdeb2b0c 563 Gene3D G3DSA:3.90.76.10 80 228 3.0E-114 T 12-10-2018 TL08_17040 e504d726a675dfed99910955bdeb2b0c 563 Gene3D G3DSA:3.40.190.10 229 542 3.0E-114 T 12-10-2018 TL08_17040 e504d726a675dfed99910955bdeb2b0c 563 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 113 479 1.1E-70 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_17040 e504d726a675dfed99910955bdeb2b0c 563 Gene3D G3DSA:3.10.105.10 304 533 3.0E-114 T 12-10-2018 TL08_19465 d5baa57758c84a23eef4fbc533634c1e 502 Gene3D G3DSA:3.90.76.10 52 192 1.3E-105 T 12-10-2018 TL08_19465 d5baa57758c84a23eef4fbc533634c1e 502 Gene3D G3DSA:3.10.105.10 273 476 1.3E-105 T 12-10-2018 TL08_19465 d5baa57758c84a23eef4fbc533634c1e 502 Gene3D G3DSA:3.40.190.10 193 484 1.3E-105 T 12-10-2018 TL08_19465 d5baa57758c84a23eef4fbc533634c1e 502 PIRSF PIRSF002741 2 496 1.6E-89 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_19465 d5baa57758c84a23eef4fbc533634c1e 502 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 409 1.8E-79 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_19465 d5baa57758c84a23eef4fbc533634c1e 502 SUPERFAMILY SSF53850 33 491 7.6E-115 T 12-10-2018 TL08_02670 6929c50b2b9bbb3238e9eb226a253706 544 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 166 532 6.2E-113 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 TL08_02670 6929c50b2b9bbb3238e9eb226a253706 544 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 19 534 17.515 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 TL08_02670 6929c50b2b9bbb3238e9eb226a253706 544 Pfam PF00361 Proton-conducting membrane transporter 186 481 3.2E-76 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_00800 8203843b596d5f59d4dc5af979d0d007 417 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 381 413 0.0019 T 12-10-2018 TL08_00800 8203843b596d5f59d4dc5af979d0d007 417 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 112 158 1.7E-13 T 12-10-2018 IPR023849 Uncharacterised domain CHP03934, TQXA TL08_08355 ff5f0055550ac5db8a665f261567b890 372 Gene3D G3DSA:3.40.50.2300 148 347 2.5E-91 T 12-10-2018 TL08_08355 ff5f0055550ac5db8a665f261567b890 372 Pfam PF13407 Periplasmic binding protein domain 46 306 1.6E-54 T 12-10-2018 IPR025997 Periplasmic binding protein TL08_08355 ff5f0055550ac5db8a665f261567b890 372 Gene3D G3DSA:3.40.50.2300 46 333 2.5E-91 T 12-10-2018 TL08_08355 ff5f0055550ac5db8a665f261567b890 372 SUPERFAMILY SSF53822 43 346 4.71E-58 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_14995 f26c00239a4051254492f2961745524c 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.3E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14995 f26c00239a4051254492f2961745524c 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.3E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14995 f26c00239a4051254492f2961745524c 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.3E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14995 f26c00239a4051254492f2961745524c 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.3E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14995 f26c00239a4051254492f2961745524c 241 Pfam PF00106 short chain dehydrogenase 5 185 5.8E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14995 f26c00239a4051254492f2961745524c 241 SUPERFAMILY SSF51735 4 210 2.13E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14995 f26c00239a4051254492f2961745524c 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 182 0.0063 T 12-10-2018 TL08_14995 f26c00239a4051254492f2961745524c 241 Gene3D G3DSA:3.40.50.720 1 230 2.0E-50 T 12-10-2018 TL08_14295 7135dad9ff2875a2411bb20483273464 445 Pfam PF07687 Peptidase dimerisation domain 205 340 4.8E-15 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TL08_14295 7135dad9ff2875a2411bb20483273464 445 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 87 96 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TL08_14295 7135dad9ff2875a2411bb20483273464 445 SUPERFAMILY SSF53187 13 444 1.11E-53 T 12-10-2018 TL08_14295 7135dad9ff2875a2411bb20483273464 445 Pfam PF01546 Peptidase family M20/M25/M40 88 444 5.2E-38 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TL08_14295 7135dad9ff2875a2411bb20483273464 445 SUPERFAMILY SSF55031 208 354 7.15E-11 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TL08_14295 7135dad9ff2875a2411bb20483273464 445 Gene3D G3DSA:3.40.630.10 12 211 1.1E-48 T 12-10-2018 TL08_07805 043e7d426b264f4953aa570e74d3f3d4 393 Pfam PF07730 Histidine kinase 186 251 1.9E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_07805 043e7d426b264f4953aa570e74d3f3d4 393 SUPERFAMILY SSF55874 274 384 5.62E-8 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_07805 043e7d426b264f4953aa570e74d3f3d4 393 Gene3D G3DSA:3.30.565.10 262 384 6.3E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_12530 016c9d0c70bb1f205788560d49b0a221 305 Gene3D G3DSA:1.10.4080.10 10 297 4.4E-56 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TL08_12530 016c9d0c70bb1f205788560d49b0a221 305 SUPERFAMILY SSF101478 12 290 4.84E-47 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TL08_12530 016c9d0c70bb1f205788560d49b0a221 305 Pfam PF03747 ADP-ribosylglycohydrolase 15 286 1.0E-43 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 TL08_16275 407169843004da607b8b7f3737228757 174 SUPERFAMILY SSF46689 3 71 1.08E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16275 407169843004da607b8b7f3737228757 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16275 407169843004da607b8b7f3737228757 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16275 407169843004da607b8b7f3737228757 174 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 1.4E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16275 407169843004da607b8b7f3737228757 174 SUPERFAMILY SSF48498 80 169 2.13E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_16275 407169843004da607b8b7f3737228757 174 Gene3D G3DSA:1.10.357.10 1 172 1.2E-49 T 12-10-2018 TL08_20370 df212d3a2dc78119286fca27ce2b05e0 142 Pfam PF12277 Protein of unknown function (DUF3618) 36 74 5.3E-12 T 12-10-2018 IPR022062 Protein of unknown function DUF3618 TL08_17015 64a27df6edaf2f41fe2a0fbc51b547af 256 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 98 250 2.0E-18 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 TL08_17015 64a27df6edaf2f41fe2a0fbc51b547af 256 Gene3D G3DSA:1.10.10.60 12 90 3.0E-26 T 12-10-2018 TL08_17015 64a27df6edaf2f41fe2a0fbc51b547af 256 SUPERFAMILY SSF46689 29 91 4.99E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_17015 64a27df6edaf2f41fe2a0fbc51b547af 256 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 84 5.4E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_17015 64a27df6edaf2f41fe2a0fbc51b547af 256 SUPERFAMILY SSF48498 103 254 1.22E-27 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_17015 64a27df6edaf2f41fe2a0fbc51b547af 256 Gene3D G3DSA:1.10.357.10 92 253 6.3E-37 T 12-10-2018 TL08_13930 2623bfae0cd2872dd0eb4ca6cac05308 265 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 22 249 8.1E-34 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TL08_13930 2623bfae0cd2872dd0eb4ca6cac05308 265 SUPERFAMILY SSF51695 15 253 8.63E-55 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_13930 2623bfae0cd2872dd0eb4ca6cac05308 265 Gene3D G3DSA:3.20.20.190 17 259 3.6E-63 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_15640 6720909bd32346003973cffc3a527772 217 Pfam PF01177 Asp/Glu/Hydantoin racemase 53 205 1.6E-7 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TL08_15640 6720909bd32346003973cffc3a527772 217 Gene3D G3DSA:3.40.50.1860 102 202 1.2E-71 T 12-10-2018 TL08_15640 6720909bd32346003973cffc3a527772 217 Gene3D G3DSA:3.40.50.1860 7 207 1.2E-71 T 12-10-2018 TL08_01705 935cea830a70228cc9e60452e14a211e 515 Pfam PF13367 Protease prsW family 80 275 1.1E-52 T 12-10-2018 IPR026898 Protease PrsW GO:0008233 TL08_20645 db237fc43fae8b2e6ee61654204c1a6d 295 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 234 7.6E-22 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_20645 db237fc43fae8b2e6ee61654204c1a6d 295 SUPERFAMILY SSF51735 2 294 8.71E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_20645 db237fc43fae8b2e6ee61654204c1a6d 295 Gene3D G3DSA:3.40.50.720 1 295 5.7E-44 T 12-10-2018 TL08_12360 5422c712b04a08d4930d289c2e9b8c2e 277 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12360 5422c712b04a08d4930d289c2e9b8c2e 277 SUPERFAMILY SSF52540 5 232 2.81E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12360 5422c712b04a08d4930d289c2e9b8c2e 277 SMART SM00382 31 220 9.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12360 5422c712b04a08d4930d289c2e9b8c2e 277 Gene3D G3DSA:3.40.50.300 1 256 6.7E-69 T 12-10-2018 TL08_12360 5422c712b04a08d4930d289c2e9b8c2e 277 Pfam PF00005 ABC transporter 23 170 5.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_17965 d2e73e7dd9f069cb5fe02ca273be6cfb 316 Pfam PF02616 Segregation and condensation protein ScpA 71 291 1.5E-58 T 12-10-2018 IPR003768 Segregation and condensation protein A TL08_13770 73ab26a0e93745a4dc25431ebd879127 420 Pfam PF02638 Glycosyl hydrolase-like 10 55 368 3.2E-92 T 12-10-2018 IPR003790 Glycosyl hydrolase-like 10 TL08_13770 73ab26a0e93745a4dc25431ebd879127 420 Gene3D G3DSA:3.20.20.70 53 274 5.4E-11 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_13770 73ab26a0e93745a4dc25431ebd879127 420 SUPERFAMILY SSF51445 82 356 7.04E-22 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_26650 e1435dcb619ff002d6dc73d3c34c122c 148 Gene3D G3DSA:2.30.22.10 86 148 1.2E-7 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TL08_26650 e1435dcb619ff002d6dc73d3c34c122c 148 Pfam PF01025 GrpE 75 141 2.1E-6 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TL08_26650 e1435dcb619ff002d6dc73d3c34c122c 148 SUPERFAMILY SSF51064 90 143 3.01E-6 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TL08_19660 aea34443230860c1c883940e55701de5 306 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 6 303 1.8E-124 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 TL08_19660 aea34443230860c1c883940e55701de5 306 Gene3D G3DSA:3.20.20.70 4 306 4.8E-94 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_19660 aea34443230860c1c883940e55701de5 306 Pfam PF00701 Dihydrodipicolinate synthetase family 16 301 2.1E-48 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_19660 aea34443230860c1c883940e55701de5 306 PIRSF PIRSF001365 11 306 3.3E-55 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_19660 aea34443230860c1c883940e55701de5 306 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 13 304 42.53 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 TL08_19660 aea34443230860c1c883940e55701de5 306 SUPERFAMILY SSF51569 15 301 5.02E-65 T 12-10-2018 TL08_19660 aea34443230860c1c883940e55701de5 306 SMART SM01130 13 304 3.3E-63 T 12-10-2018 IPR002220 DapA-like GO:0016829 TL08_25460 3f7221516d8fbffcc8f84c2494951a56 242 SMART SM00382 46 234 2.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_25460 3f7221516d8fbffcc8f84c2494951a56 242 SUPERFAMILY SSF52540 23 240 1.97E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25460 3f7221516d8fbffcc8f84c2494951a56 242 Pfam PF00005 ABC transporter 38 185 4.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_25460 3f7221516d8fbffcc8f84c2494951a56 242 Gene3D G3DSA:3.40.50.300 19 242 8.4E-65 T 12-10-2018 TL08_15945 40dd0eb2a1cf5454b315026084fd317e 201 SUPERFAMILY SSF51182 1 195 1.09E-63 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_15945 40dd0eb2a1cf5454b315026084fd317e 201 Gene3D G3DSA:2.60.120.10 1 199 3.5E-61 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_15945 40dd0eb2a1cf5454b315026084fd317e 201 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 166 5.0E-57 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TL08_15945 40dd0eb2a1cf5454b315026084fd317e 201 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 1.7E-50 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TL08_12890 1a8cf5d086d998f0580d437b6426fe0e 402 SUPERFAMILY SSF89796 11 402 3.27E-133 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TL08_12890 1a8cf5d086d998f0580d437b6426fe0e 402 Gene3D G3DSA:3.40.50.10540 12 396 3.1E-131 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TL08_12890 1a8cf5d086d998f0580d437b6426fe0e 402 Pfam PF02515 CoA-transferase family III 13 378 3.7E-125 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 TL08_12890 1a8cf5d086d998f0580d437b6426fe0e 402 Gene3D G3DSA:3.30.1540.10 233 330 3.1E-131 T 12-10-2018 TL08_15585 cb516df67917a796eda9878f0cbaa1ce 332 SUPERFAMILY SSF53807 52 327 1.49E-37 T 12-10-2018 TL08_15585 cb516df67917a796eda9878f0cbaa1ce 332 Pfam PF01497 Periplasmic binding protein 56 305 6.5E-23 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TL08_15585 cb516df67917a796eda9878f0cbaa1ce 332 Gene3D G3DSA:3.40.50.1980 160 331 6.2E-57 T 12-10-2018 TL08_15585 cb516df67917a796eda9878f0cbaa1ce 332 Gene3D G3DSA:3.40.50.1980 33 155 2.0E-16 T 12-10-2018 TL08_25285 aaf093587f80795401fdef27bbe6cdf9 156 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 148 1.6E-58 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25285 aaf093587f80795401fdef27bbe6cdf9 156 Gene3D G3DSA:3.30.70.640 1 156 4.2E-59 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25285 aaf093587f80795401fdef27bbe6cdf9 156 Pfam PF01967 MoaC family 14 147 6.4E-49 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25285 aaf093587f80795401fdef27bbe6cdf9 156 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 1 155 33.381 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_25285 aaf093587f80795401fdef27bbe6cdf9 156 SUPERFAMILY SSF55040 10 152 5.49E-52 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TL08_10970 15a4b810ba8ac5b4efd69a66cb960090 252 Gene3D G3DSA:3.40.50.12500 18 250 6.4E-64 T 12-10-2018 TL08_10970 15a4b810ba8ac5b4efd69a66cb960090 252 PIRSF PIRSF015736 14 248 2.0E-64 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase TL08_09540 dbb9747918dfe0a0084588c1767be26a 248 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 92 106 - T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TL08_09540 dbb9747918dfe0a0084588c1767be26a 248 Gene3D G3DSA:3.20.20.10 2 248 2.0E-74 T 12-10-2018 IPR029066 PLP-binding barrel TL08_09540 dbb9747918dfe0a0084588c1767be26a 248 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 18 244 26.83 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TL08_09540 dbb9747918dfe0a0084588c1767be26a 248 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 23 245 6.6E-42 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TL08_09540 dbb9747918dfe0a0084588c1767be26a 248 SUPERFAMILY SSF51419 14 243 3.43E-61 T 12-10-2018 IPR029066 PLP-binding barrel TL08_09540 dbb9747918dfe0a0084588c1767be26a 248 PIRSF PIRSF004848 13 248 6.4E-61 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TL08_09540 dbb9747918dfe0a0084588c1767be26a 248 Pfam PF01168 Alanine racemase, N-terminal domain 32 246 2.0E-20 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TL08_09025 cc4f9a79f471f7c02e9a7ef4916861ef 178 SUPERFAMILY SSF49777 7 170 7.33E-46 T 12-10-2018 IPR036610 PEBP-like superfamily TL08_09025 cc4f9a79f471f7c02e9a7ef4916861ef 178 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 42 176 9.1E-40 T 12-10-2018 IPR005247 YbhB/YbcL TL08_09025 cc4f9a79f471f7c02e9a7ef4916861ef 178 Gene3D G3DSA:3.90.280.10 6 178 4.0E-50 T 12-10-2018 IPR036610 PEBP-like superfamily TL08_09025 cc4f9a79f471f7c02e9a7ef4916861ef 178 Pfam PF01161 Phosphatidylethanolamine-binding protein 44 174 1.4E-33 T 12-10-2018 IPR008914 Phosphatidylethanolamine-binding protein TL08_04740 eeb32e740709b0956c0dcebe9d1ad48b 277 Pfam PF12705 PD-(D/E)XK nuclease superfamily 15 259 2.4E-33 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TL08_18740 fdc95b734bec39ae773ffbcadc39c114 134 SUPERFAMILY SSF46689 60 112 1.34E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18740 fdc95b734bec39ae773ffbcadc39c114 134 Pfam PF12833 Helix-turn-helix domain 30 108 1.4E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_18740 fdc95b734bec39ae773ffbcadc39c114 134 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 76 91 7.5E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_18740 fdc95b734bec39ae773ffbcadc39c114 134 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 91 107 7.5E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TL08_18740 fdc95b734bec39ae773ffbcadc39c114 134 SUPERFAMILY SSF46689 8 58 2.83E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18740 fdc95b734bec39ae773ffbcadc39c114 134 SMART SM00342 24 107 3.5E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_18740 fdc95b734bec39ae773ffbcadc39c114 134 Gene3D G3DSA:1.10.10.60 4 113 1.8E-30 T 12-10-2018 TL08_14275 e872353f87b127db00ca29852a0a7c94 349 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 321 7.9E-118 T 12-10-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c TL08_14275 e872353f87b127db00ca29852a0a7c94 349 SUPERFAMILY SSF51679 11 339 1.22E-69 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_14275 e872353f87b127db00ca29852a0a7c94 349 Pfam PF00296 Luciferase-like monooxygenase 16 317 1.7E-78 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_14275 e872353f87b127db00ca29852a0a7c94 349 Gene3D G3DSA:3.20.20.30 10 341 3.6E-84 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_04730 f93f2f43806cf3bd967905be5a4b9645 189 Pfam PF03703 Bacterial PH domain 81 147 7.5E-12 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 SUPERFAMILY SSF51735 2 242 2.14E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 Pfam PF00106 short chain dehydrogenase 4 186 4.2E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 3.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 3.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_06915 a703efa512081a9c87ff46cf28fe63ea 279 Gene3D G3DSA:3.40.50.720 2 278 6.4E-68 T 12-10-2018 TL08_19830 c8f349797dd63ce0085b2ca2e97a24ae 284 Pfam PF03756 A-factor biosynthesis hotdog domain 101 233 6.2E-18 T 12-10-2018 IPR005509 A-factor biosynthesis hotdog domain TL08_19970 1de7735ad7054024695f0f12bb0eb110 318 Pfam PF00248 Aldo/keto reductase family 21 316 6.7E-61 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_19970 1de7735ad7054024695f0f12bb0eb110 318 Gene3D G3DSA:3.20.20.100 8 318 4.6E-93 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_19970 1de7735ad7054024695f0f12bb0eb110 318 SUPERFAMILY SSF51430 9 316 3.8E-82 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_00710 da49e43f28d3820deac3d8a3af2ca7c6 317 SUPERFAMILY SSF53448 27 291 5.87E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00710 da49e43f28d3820deac3d8a3af2ca7c6 317 Pfam PF00535 Glycosyl transferase family 2 30 189 1.6E-13 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_00710 da49e43f28d3820deac3d8a3af2ca7c6 317 Gene3D G3DSA:3.90.550.10 10 238 8.2E-20 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00665 d37f6adcdd8b976af867299f25a116a1 310 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 6.4E-60 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_00665 d37f6adcdd8b976af867299f25a116a1 310 SUPERFAMILY SSF51735 1 309 1.17E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_00665 d37f6adcdd8b976af867299f25a116a1 310 Gene3D G3DSA:3.90.25.10 178 306 5.4E-96 T 12-10-2018 TL08_00665 d37f6adcdd8b976af867299f25a116a1 310 Gene3D G3DSA:3.40.50.720 4 241 5.4E-96 T 12-10-2018 TL08_18865 33e8d6ab5922a2687dcf0645b78e557b 106 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 98 7.4E-9 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 SMART SM00740 371 438 1.5E-12 T 12-10-2018 IPR005543 PASTA domain TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 SMART SM00740 439 508 2.8E-9 T 12-10-2018 IPR005543 PASTA domain TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 SMART SM00740 575 643 7.1E-5 T 12-10-2018 IPR005543 PASTA domain TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 SMART SM00740 509 574 6.6E-13 T 12-10-2018 IPR005543 PASTA domain TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Gene3D G3DSA:1.10.510.10 96 284 8.5E-56 T 12-10-2018 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 SUPERFAMILY SSF54184 578 641 3.66E-5 T 12-10-2018 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Gene3D G3DSA:3.30.10.20 372 440 5.7E-16 T 12-10-2018 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Gene3D G3DSA:3.30.10.20 510 575 4.3E-14 T 12-10-2018 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Pfam PF03793 PASTA domain 579 641 2.6E-10 T 12-10-2018 IPR005543 PASTA domain TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Pfam PF03793 PASTA domain 444 507 9.6E-12 T 12-10-2018 IPR005543 PASTA domain TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Pfam PF03793 PASTA domain 375 436 9.8E-13 T 12-10-2018 IPR005543 PASTA domain TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Pfam PF03793 PASTA domain 519 573 5.2E-13 T 12-10-2018 IPR005543 PASTA domain TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Gene3D G3DSA:3.30.10.20 444 508 1.6E-11 T 12-10-2018 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 SUPERFAMILY SSF56112 8 279 9.31E-77 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Pfam PF00069 Protein kinase domain 11 264 5.1E-50 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 SMART SM00220 11 274 1.4E-64 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Gene3D G3DSA:3.30.10.20 576 642 2.6E-10 T 12-10-2018 TL08_00120 e05fc69ef5d52a93c2658cf84918ca94 666 Gene3D G3DSA:3.30.200.20 1 94 6.0E-35 T 12-10-2018 TL08_20605 43c9dea0c68b0eee67ce6834e7d41859 524 SUPERFAMILY SSF53474 100 510 1.32E-17 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_20605 43c9dea0c68b0eee67ce6834e7d41859 524 Pfam PF00561 alpha/beta hydrolase fold 115 494 8.4E-38 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 SUPERFAMILY SSF56645 13 245 3.66E-68 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 Gene3D G3DSA:1.20.140.10 240 385 4.7E-50 T 12-10-2018 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 PIRSF PIRSF016578 4 372 1.7E-21 T 12-10-2018 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 SUPERFAMILY SSF47203 232 383 5.8E-54 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 1.7E-22 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 122 4.1E-26 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 Gene3D G3DSA:1.10.540.10 9 124 8.6E-29 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 2.0E-45 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TL08_02350 560eb5d85fee03f8eb2ba7fa1a244eaa 385 Gene3D G3DSA:2.40.110.10 126 239 2.2E-36 T 12-10-2018 TL08_22205 27848a9bee7a709d65c00939724e2f8e 402 Pfam PF13556 PucR C-terminal helix-turn-helix domain 334 392 2.1E-21 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain TL08_22205 27848a9bee7a709d65c00939724e2f8e 402 Gene3D G3DSA:1.10.10.2840 270 398 1.7E-41 T 12-10-2018 TL08_11830 e97c5627545875890eeb26620ef03a68 153 SUPERFAMILY SSF82649 2 145 1.26E-42 T 12-10-2018 TL08_11830 e97c5627545875890eeb26620ef03a68 153 Pfam PF01592 NifU-like N terminal domain 6 131 5.1E-28 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 TL08_11830 e97c5627545875890eeb26620ef03a68 153 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 143 4.4E-46 T 12-10-2018 TL08_11830 e97c5627545875890eeb26620ef03a68 153 Gene3D G3DSA:3.90.1010.10 1 148 6.9E-45 T 12-10-2018 TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 Gene3D G3DSA:3.40.1410.10 75 233 5.5E-39 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 SUPERFAMILY SSF46785 2 73 9.24E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 SMART SM00866 91 230 6.7E-29 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 6.0E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 SUPERFAMILY SSF64288 58 228 7.54E-41 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 Pfam PF07702 UTRA domain 93 228 2.7E-32 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 SMART SM00345 10 69 4.4E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_12920 cb677fc07596d590cfd228f3e634dbb2 237 Gene3D G3DSA:1.10.10.10 4 73 1.2E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_23540 25f82dcabc352b0fab5b300b9d08bc28 211 Pfam PF04138 GtrA-like protein 27 157 2.7E-22 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TL08_13165 0c3f387d27e1ff1f93975509c8b49d26 472 Gene3D G3DSA:3.40.50.300 51 260 9.4E-29 T 12-10-2018 TL08_13165 0c3f387d27e1ff1f93975509c8b49d26 472 SUPERFAMILY SSF52540 51 340 3.36E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13165 0c3f387d27e1ff1f93975509c8b49d26 472 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 196 243 7.2E-6 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TL08_12195 8b37c8f7b74e16ed8e89801911f72556 333 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 41 286 5.0E-35 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 TL08_12195 8b37c8f7b74e16ed8e89801911f72556 333 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 149 158 - T 12-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 TL08_12195 8b37c8f7b74e16ed8e89801911f72556 333 Gene3D G3DSA:3.20.20.80 22 327 6.4E-85 T 12-10-2018 TL08_12195 8b37c8f7b74e16ed8e89801911f72556 333 SUPERFAMILY SSF51445 30 321 5.8E-75 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_14360 37d3792b9640ebfd7f8e6433ada3e050 438 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 4 412 6.9E-132 T 12-10-2018 IPR021228 Protein of unknown function DUF2791 TL08_14360 37d3792b9640ebfd7f8e6433ada3e050 438 SUPERFAMILY SSF52540 55 307 5.83E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09510 232e3a2419887f492b9cb89cda8cc2fc 295 Gene3D G3DSA:2.40.100.10 179 293 4.1E-41 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TL08_09510 232e3a2419887f492b9cb89cda8cc2fc 295 SUPERFAMILY SSF50891 183 290 1.52E-14 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TL08_09510 232e3a2419887f492b9cb89cda8cc2fc 295 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 33 289 2.2E-85 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TL08_09510 232e3a2419887f492b9cb89cda8cc2fc 295 SMART SM00797 32 295 6.0E-99 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TL08_09510 232e3a2419887f492b9cb89cda8cc2fc 295 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 10 290 3.3E-86 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TL08_02220 ca5d944496be0dccb8ed65408735158c 273 Gene3D G3DSA:3.40.50.150 29 255 2.6E-7 T 12-10-2018 TL08_02220 ca5d944496be0dccb8ed65408735158c 273 SUPERFAMILY SSF53335 40 173 4.09E-9 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_21795 56cc7f84d6941c90d9d7a7c99ea6cf7d 311 SUPERFAMILY SSF53613 11 282 3.27E-47 T 12-10-2018 IPR029056 Ribokinase-like TL08_21795 56cc7f84d6941c90d9d7a7c99ea6cf7d 311 Gene3D G3DSA:3.40.1190.20 1 309 2.8E-72 T 12-10-2018 IPR029056 Ribokinase-like TL08_21795 56cc7f84d6941c90d9d7a7c99ea6cf7d 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 33 57 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TL08_21795 56cc7f84d6941c90d9d7a7c99ea6cf7d 311 Pfam PF00294 pfkB family carbohydrate kinase 14 281 2.8E-38 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_16720 de1b0d941da39507887fbcb13e94dd20 167 Pfam PF13577 SnoaL-like domain 15 145 8.9E-26 T 12-10-2018 IPR037401 SnoaL-like domain TL08_16720 de1b0d941da39507887fbcb13e94dd20 167 Gene3D G3DSA:3.10.450.50 12 166 1.3E-44 T 12-10-2018 TL08_16720 de1b0d941da39507887fbcb13e94dd20 167 SUPERFAMILY SSF54427 16 159 3.88E-34 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_16720 de1b0d941da39507887fbcb13e94dd20 167 ProDom PD022193 DEHYDRATASE SCYTALONE LYASE MELANIN BIOSYNTHESIS 3D-STRUCTURE PROBABLE CONIDIATION I SPORULATION 30 155 0.005 T 12-10-2018 IPR004235 Scytalone dehydratase GO:0006582|GO:0030411 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 SUPERFAMILY SSF52540 70 252 1.46E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 Gene3D G3DSA:1.25.40.10 613 792 1.9E-45 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 SUPERFAMILY SSF48452 644 779 7.59E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 PRINTS PR00364 Disease resistance protein signature 231 245 4.7E-5 T 12-10-2018 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 PRINTS PR00364 Disease resistance protein signature 146 160 4.7E-5 T 12-10-2018 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 PRINTS PR00364 Disease resistance protein signature 72 87 4.7E-5 T 12-10-2018 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 Pfam PF13424 Tetratricopeptide repeat 610 678 6.4E-10 T 12-10-2018 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 SUPERFAMILY SSF48452 560 678 1.52E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 Pfam PF00931 NB-ARC domain 70 249 9.8E-12 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 Pfam PF13374 Tetratricopeptide repeat 733 773 0.007 T 12-10-2018 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 Pfam PF13374 Tetratricopeptide repeat 691 732 0.0092 T 12-10-2018 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 Pfam PF13374 Tetratricopeptide repeat 565 606 0.0012 T 12-10-2018 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 Gene3D G3DSA:3.40.50.300 48 193 1.4E-23 T 12-10-2018 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 Gene3D G3DSA:1.25.40.10 443 596 5.9E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_05765 5e575d44ed676d38ef29de17bf16132b 800 SUPERFAMILY SSF48452 439 551 5.06E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_10315 e662615271e35f0b75baed44bc991924 219 Gene3D G3DSA:3.40.630.30 4 198 3.4E-26 T 12-10-2018 TL08_10315 e662615271e35f0b75baed44bc991924 219 SUPERFAMILY SSF55729 4 199 1.15E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_10315 e662615271e35f0b75baed44bc991924 219 Pfam PF00583 Acetyltransferase (GNAT) family 106 173 1.5E-5 T 12-10-2018 IPR000182 GNAT domain TL08_04035 d80cc60197773ab37851f785e42de6ba 166 Gene3D G3DSA:1.10.10.10 6 60 3.5E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04035 d80cc60197773ab37851f785e42de6ba 166 SMART SM00344 10 116 9.3E-22 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TL08_04035 d80cc60197773ab37851f785e42de6ba 166 SUPERFAMILY SSF54909 70 154 2.41E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_04035 d80cc60197773ab37851f785e42de6ba 166 Gene3D G3DSA:3.30.70.920 63 152 5.7E-21 T 12-10-2018 TL08_04035 d80cc60197773ab37851f785e42de6ba 166 SUPERFAMILY SSF46785 10 70 6.56E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_04035 d80cc60197773ab37851f785e42de6ba 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 1.1E-6 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_04035 d80cc60197773ab37851f785e42de6ba 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 1.1E-6 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_04035 d80cc60197773ab37851f785e42de6ba 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 1.1E-6 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_04035 d80cc60197773ab37851f785e42de6ba 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 56 3.2E-6 T 12-10-2018 TL08_04035 d80cc60197773ab37851f785e42de6ba 166 Pfam PF01037 Lrp/AsnC ligand binding domain 84 146 5.2E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TL08_04220 b68dc9c9ca7187a5261b745a72561ed7 332 Pfam PF02646 RmuC family 59 265 1.0E-38 T 12-10-2018 IPR003798 DNA recombination RmuC TL08_22145 3293b15b3283e62ac2336e7c0db07f43 154 SUPERFAMILY SSF52833 1 152 2.24E-45 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_22145 3293b15b3283e62ac2336e7c0db07f43 154 Gene3D G3DSA:3.40.30.10 1 153 9.2E-50 T 12-10-2018 TL08_22145 3293b15b3283e62ac2336e7c0db07f43 154 Pfam PF00578 AhpC/TSA family 5 130 1.8E-37 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TL08_22145 3293b15b3283e62ac2336e7c0db07f43 154 PIRSF PIRSF000239 1 150 4.6E-25 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TL08_14115 49b54ef71cf28129010519c708b28eaa 276 Pfam PF00805 Pentapeptide repeats (8 copies) 192 229 7.9E-12 T 12-10-2018 IPR001646 Pentapeptide repeat TL08_14115 49b54ef71cf28129010519c708b28eaa 276 Gene3D G3DSA:2.160.20.80 160 272 1.6E-20 T 12-10-2018 TL08_14115 49b54ef71cf28129010519c708b28eaa 276 SUPERFAMILY SSF141571 60 272 1.57E-22 T 12-10-2018 TL08_20760 a4651bf7680b94c66fc0d29d9965f24c 109 Gene3D G3DSA:1.10.287.1060 4 103 8.3E-11 T 12-10-2018 TL08_20760 a4651bf7680b94c66fc0d29d9965f24c 109 SUPERFAMILY SSF140453 5 101 3.66E-6 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_18575 5d3512c37d7d0dfb9a00d1e26be741af 255 Gene3D G3DSA:1.10.1660.10 2 254 7.3E-25 T 12-10-2018 TL08_18575 5d3512c37d7d0dfb9a00d1e26be741af 255 SUPERFAMILY SSF46955 2 101 5.04E-20 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_18575 5d3512c37d7d0dfb9a00d1e26be741af 255 SMART SM00422 1 70 3.1E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_18575 5d3512c37d7d0dfb9a00d1e26be741af 255 Pfam PF00376 MerR family regulatory protein 4 39 1.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_06020 9f7fd3cbcf0eeecace31b468ba091fad 212 SUPERFAMILY SSF48498 89 203 9.3E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_06020 9f7fd3cbcf0eeecace31b468ba091fad 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 68 3.6E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06020 9f7fd3cbcf0eeecace31b468ba091fad 212 Gene3D G3DSA:1.10.357.10 2 210 1.6E-28 T 12-10-2018 TL08_06020 9f7fd3cbcf0eeecace31b468ba091fad 212 SUPERFAMILY SSF46689 9 92 8.72E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_23490 a3edac65923a7b12c2a718d6dca725a9 356 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 310 1.0E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_04080 96babb93391156f68cf5bc3aa7147969 292 Gene3D G3DSA:3.40.50.150 20 282 1.6E-70 T 12-10-2018 TL08_04080 96babb93391156f68cf5bc3aa7147969 292 SUPERFAMILY SSF53335 37 247 1.41E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13465 b0c9624f2093fa775df77a2cf877428d 216 SUPERFAMILY SSF55961 21 164 2.26E-31 T 12-10-2018 TL08_13465 b0c9624f2093fa775df77a2cf877428d 216 Gene3D G3DSA:3.30.530.20 7 192 9.6E-42 T 12-10-2018 IPR023393 START-like domain superfamily TL08_13465 b0c9624f2093fa775df77a2cf877428d 216 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 35 156 3.7E-16 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TL08_25315 256a6772eb863bb9fa4898405ec8e026 140 Pfam PF03259 Roadblock/LC7 domain 13 102 2.9E-24 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TL08_25315 256a6772eb863bb9fa4898405ec8e026 140 SMART SM00960 12 102 1.1E-32 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TL08_25315 256a6772eb863bb9fa4898405ec8e026 140 Gene3D G3DSA:3.30.450.30 10 133 1.6E-44 T 12-10-2018 TL08_25315 256a6772eb863bb9fa4898405ec8e026 140 SUPERFAMILY SSF103196 5 129 9.42E-35 T 12-10-2018 TL08_13780 50a3b0fedbea7da150d57c50667da0f0 264 SUPERFAMILY SSF53335 59 239 5.86E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13780 50a3b0fedbea7da150d57c50667da0f0 264 Gene3D G3DSA:3.40.50.150 56 239 3.3E-14 T 12-10-2018 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00463 E-class P450 group I signature 263 289 3.7E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00463 E-class P450 group I signature 392 415 3.7E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00463 E-class P450 group I signature 382 392 3.7E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00463 E-class P450 group I signature 32 51 3.7E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00463 E-class P450 group I signature 345 369 3.7E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00463 E-class P450 group I signature 243 260 3.7E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 SUPERFAMILY SSF48264 23 440 3.93E-95 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 385 394 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00385 P450 superfamily signature 254 271 1.0E-9 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00385 P450 superfamily signature 306 317 1.0E-9 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00385 P450 superfamily signature 392 403 1.0E-9 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 PRINTS PR00385 P450 superfamily signature 383 392 1.0E-9 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 Pfam PF00067 Cytochrome P450 29 424 2.5E-64 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_20980 123f449ebb7f8c67815acdd922b79492 444 Gene3D G3DSA:1.10.630.10 16 442 9.5E-104 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_08890 6a954d56816dd7bcc54e28f7af175133 309 Pfam PF01148 Cytidylyltransferase family 50 304 5.1E-55 T 12-10-2018 TL08_08890 6a954d56816dd7bcc54e28f7af175133 309 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 263 289 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 TL08_12540 76856fda8c158dfab6bac7afee663f7b 270 Pfam PF00149 Calcineurin-like phosphoesterase 2 233 3.8E-18 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_12540 76856fda8c158dfab6bac7afee663f7b 270 SUPERFAMILY SSF56300 2 260 1.82E-29 T 12-10-2018 TL08_12540 76856fda8c158dfab6bac7afee663f7b 270 Gene3D G3DSA:3.60.21.10 1 250 2.4E-12 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_11995 feb41a750af30be50daa975c3a5183b8 262 SUPERFAMILY SSF46689 194 243 1.43E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_11995 feb41a750af30be50daa975c3a5183b8 262 SMART SM00342 158 241 7.2E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_11995 feb41a750af30be50daa975c3a5183b8 262 Pfam PF12852 Cupin 1 122 1.8E-22 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain TL08_11995 feb41a750af30be50daa975c3a5183b8 262 Gene3D G3DSA:1.10.10.60 137 252 9.1E-25 T 12-10-2018 TL08_11995 feb41a750af30be50daa975c3a5183b8 262 Pfam PF12833 Helix-turn-helix domain 164 242 6.1E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_11995 feb41a750af30be50daa975c3a5183b8 262 SUPERFAMILY SSF46689 143 191 3.05E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14100 48e3ecfd0be04c061aaa6ec1ebb695e1 234 SUPERFAMILY SSF46689 30 100 2.57E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14100 48e3ecfd0be04c061aaa6ec1ebb695e1 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 82 3.2E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14100 48e3ecfd0be04c061aaa6ec1ebb695e1 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 53 4.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14100 48e3ecfd0be04c061aaa6ec1ebb695e1 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 61 84 4.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14100 48e3ecfd0be04c061aaa6ec1ebb695e1 234 Gene3D G3DSA:1.10.357.10 25 228 3.3E-38 T 12-10-2018 TL08_09320 01034d9efb7b18ecf9e35cc4cf303c3c 457 Pfam PF06224 Winged helix DNA-binding domain 50 396 1.7E-77 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 TL08_03440 c598aa6e58cc305296a08a239c4d4cb9 287 Gene3D G3DSA:3.20.20.100 3 287 1.4E-71 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_03440 c598aa6e58cc305296a08a239c4d4cb9 287 SUPERFAMILY SSF51430 5 285 5.76E-69 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_03440 c598aa6e58cc305296a08a239c4d4cb9 287 Pfam PF00248 Aldo/keto reductase family 14 284 5.5E-55 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_07700 cb8235c59e2e1c9f148c2bf637cce899 137 Pfam PF13471 Transglutaminase-like superfamily 22 132 1.7E-26 T 12-10-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal TL08_13810 f4127501795f7693f476ef488e1e7233 254 Gene3D G3DSA:3.40.630.30 38 240 1.8E-65 T 12-10-2018 TL08_13810 f4127501795f7693f476ef488e1e7233 254 Pfam PF00583 Acetyltransferase (GNAT) family 86 220 3.4E-7 T 12-10-2018 IPR000182 GNAT domain TL08_13810 f4127501795f7693f476ef488e1e7233 254 SUPERFAMILY SSF55729 42 223 2.3E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_14255 111cccaafb3877315c32417889f785a0 232 Gene3D G3DSA:3.40.50.1240 1 208 2.3E-43 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_14255 111cccaafb3877315c32417889f785a0 232 SUPERFAMILY SSF53254 1 200 3.85E-41 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_14255 111cccaafb3877315c32417889f785a0 232 SMART SM00855 3 161 9.9E-17 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_14255 111cccaafb3877315c32417889f785a0 232 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 201 2.8E-44 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_14255 111cccaafb3877315c32417889f785a0 232 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 206 1.2E-96 T 12-10-2018 IPR022492 Phosphomutase MSMEG4193, putative TL08_12835 48d1cb147f01a5a61a0b7585ee9d97c1 136 PRINTS PR01217 Proline rich extensin signature 89 114 1.6E-10 T 12-10-2018 TL08_12835 48d1cb147f01a5a61a0b7585ee9d97c1 136 PRINTS PR01217 Proline rich extensin signature 29 50 1.6E-10 T 12-10-2018 TL08_12835 48d1cb147f01a5a61a0b7585ee9d97c1 136 PRINTS PR01217 Proline rich extensin signature 50 66 1.6E-10 T 12-10-2018 TL08_12835 48d1cb147f01a5a61a0b7585ee9d97c1 136 PRINTS PR01217 Proline rich extensin signature 71 88 1.6E-10 T 12-10-2018 TL08_11525 337fe390c5d20872304b31031e956a8c 416 SUPERFAMILY SSF52507 16 183 5.49E-55 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TL08_11525 337fe390c5d20872304b31031e956a8c 416 Gene3D G3DSA:3.40.50.10300 193 416 3.6E-82 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TL08_11525 337fe390c5d20872304b31031e956a8c 416 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 198 385 3.3E-67 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TL08_11525 337fe390c5d20872304b31031e956a8c 416 Pfam PF02441 Flavoprotein 18 182 2.0E-38 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TL08_11525 337fe390c5d20872304b31031e956a8c 416 Gene3D G3DSA:3.40.50.1950 14 192 2.6E-51 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TL08_11525 337fe390c5d20872304b31031e956a8c 416 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 410 1.1E-117 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 TL08_11525 337fe390c5d20872304b31031e956a8c 416 SUPERFAMILY SSF102645 196 414 8.5E-67 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TL08_21935 def39439aae6d903d009130879b2b13e 304 Gene3D G3DSA:1.20.120.350 4 116 4.7E-29 T 12-10-2018 IPR027359 Voltage-dependent channel domain superfamily TL08_21935 def39439aae6d903d009130879b2b13e 304 Pfam PF00520 Ion transport protein 14 225 1.1E-44 T 12-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 TL08_21935 def39439aae6d903d009130879b2b13e 304 SUPERFAMILY SSF81324 13 223 1.02E-36 T 12-10-2018 TL08_21935 def39439aae6d903d009130879b2b13e 304 Gene3D G3DSA:1.10.287.70 117 214 7.5E-30 T 12-10-2018 TL08_02325 50d719b21e89b3298a1382e76825d705 71 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 17 64 5.6E-20 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TL08_02325 50d719b21e89b3298a1382e76825d705 71 SUPERFAMILY SSF46955 16 64 1.56E-5 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_02325 50d719b21e89b3298a1382e76825d705 71 Gene3D G3DSA:1.10.1660.10 14 66 1.0E-10 T 12-10-2018 TL08_02325 50d719b21e89b3298a1382e76825d705 71 Pfam PF12728 Helix-turn-helix domain 17 65 1.5E-14 T 12-10-2018 TL08_19325 1eb297c9dbce2200051078c8d0d9a747 275 SUPERFAMILY SSF51735 3 203 2.84E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19325 1eb297c9dbce2200051078c8d0d9a747 275 Gene3D G3DSA:3.40.50.720 2 242 2.6E-35 T 12-10-2018 TL08_19325 1eb297c9dbce2200051078c8d0d9a747 275 Pfam PF00106 short chain dehydrogenase 4 136 3.3E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14505 738386d1ffea4bc9fc1ae14bc0f66a35 310 Pfam PF13560 Helix-turn-helix domain 21 101 3.2E-17 T 12-10-2018 TL08_14505 738386d1ffea4bc9fc1ae14bc0f66a35 310 SMART SM00530 25 98 1.0E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_14505 738386d1ffea4bc9fc1ae14bc0f66a35 310 Gene3D G3DSA:3.30.450.180 121 291 8.3E-12 T 12-10-2018 TL08_14505 738386d1ffea4bc9fc1ae14bc0f66a35 310 Gene3D G3DSA:1.10.260.40 19 100 7.9E-6 T 12-10-2018 TL08_14505 738386d1ffea4bc9fc1ae14bc0f66a35 310 SUPERFAMILY SSF47413 46 97 1.46E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_09080 b2f20f51e6ea72f014e0f5202a964cb0 152 SUPERFAMILY SSF55729 11 150 4.43E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_09080 b2f20f51e6ea72f014e0f5202a964cb0 152 Gene3D G3DSA:3.40.630.30 5 148 1.0E-35 T 12-10-2018 TL08_09080 b2f20f51e6ea72f014e0f5202a964cb0 152 Pfam PF13673 Acetyltransferase (GNAT) domain 75 147 2.8E-12 T 12-10-2018 IPR000182 GNAT domain TL08_18615 6b0c18ae59cc15f23a9c4006218af5c3 191 Pfam PF01872 RibD C-terminal domain 5 183 7.2E-24 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TL08_18615 6b0c18ae59cc15f23a9c4006218af5c3 191 SUPERFAMILY SSF53597 4 189 1.51E-21 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_18615 6b0c18ae59cc15f23a9c4006218af5c3 191 Gene3D G3DSA:3.40.430.10 2 189 7.1E-34 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_20145 cb5486752dcd91dd54a5d59c85780604 213 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 26 208 2.8E-21 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 TL08_20145 cb5486752dcd91dd54a5d59c85780604 213 Gene3D G3DSA:3.30.70.1210 93 209 3.6E-22 T 12-10-2018 TL08_20145 cb5486752dcd91dd54a5d59c85780604 213 SUPERFAMILY SSF117987 94 208 7.06E-23 T 12-10-2018 TL08_20145 cb5486752dcd91dd54a5d59c85780604 213 SMART SM01101 3 208 1.8E-52 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 TL08_20145 cb5486752dcd91dd54a5d59c85780604 213 Gene3D G3DSA:3.30.70.1200 1 89 1.2E-20 T 12-10-2018 TL08_20145 cb5486752dcd91dd54a5d59c85780604 213 Pfam PF08798 CRISPR associated protein 4 208 1.3E-47 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 TL08_20145 cb5486752dcd91dd54a5d59c85780604 213 SUPERFAMILY SSF117987 3 86 1.33E-17 T 12-10-2018 TL08_05510 426b94365fb99649ca3852e17180bad7 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 1.8E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05510 426b94365fb99649ca3852e17180bad7 200 Pfam PF00072 Response regulator receiver domain 4 115 8.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_05510 426b94365fb99649ca3852e17180bad7 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05510 426b94365fb99649ca3852e17180bad7 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 2.9E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05510 426b94365fb99649ca3852e17180bad7 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 2.9E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05510 426b94365fb99649ca3852e17180bad7 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 2.9E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_05510 426b94365fb99649ca3852e17180bad7 200 Gene3D G3DSA:3.40.50.12740 3 200 2.2E-52 T 12-10-2018 TL08_05510 426b94365fb99649ca3852e17180bad7 200 SUPERFAMILY SSF52172 1 129 1.01E-27 T 12-10-2018 IPR011006 CheY-like superfamily TL08_05510 426b94365fb99649ca3852e17180bad7 200 SMART SM00448 2 115 1.0E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_05510 426b94365fb99649ca3852e17180bad7 200 SUPERFAMILY SSF46894 130 200 1.33E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_05510 426b94365fb99649ca3852e17180bad7 200 SMART SM00421 137 194 1.0E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14260 f5c415a4e4c246dd4f4b4c9d3a937ae3 374 Pfam PF00144 Beta-lactamase 42 338 3.5E-54 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_14260 f5c415a4e4c246dd4f4b4c9d3a937ae3 374 SUPERFAMILY SSF56601 40 346 2.68E-73 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_14260 f5c415a4e4c246dd4f4b4c9d3a937ae3 374 Gene3D G3DSA:3.40.710.10 32 361 2.3E-98 T 12-10-2018 TL08_07040 1292b28c7d15364903c631d97e7273b8 323 Gene3D G3DSA:1.10.3720.10 74 323 4.6E-72 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07040 1292b28c7d15364903c631d97e7273b8 323 SUPERFAMILY SSF161098 78 311 1.26E-61 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07040 1292b28c7d15364903c631d97e7273b8 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 319 9.8E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_01495 183e6a40fd0210dbc1c062ae1ff46608 773 PIRSF PIRSF001265 19 724 1.2E-244 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TL08_01495 183e6a40fd0210dbc1c062ae1ff46608 773 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 27 717 7.5E-202 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TL08_01495 183e6a40fd0210dbc1c062ae1ff46608 773 Pfam PF03030 Inorganic H+ pyrophosphatase 34 711 1.1E-234 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TL08_01495 183e6a40fd0210dbc1c062ae1ff46608 773 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 22 716 23.894 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TL08_15510 25a42473b123c616811ce0f0b31b6402 122 Pfam PF12680 SnoaL-like domain 9 110 7.6E-13 T 12-10-2018 IPR037401 SnoaL-like domain TL08_15510 25a42473b123c616811ce0f0b31b6402 122 SUPERFAMILY SSF54427 1 117 7.64E-35 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_15510 25a42473b123c616811ce0f0b31b6402 122 Gene3D G3DSA:3.10.450.50 1 120 1.8E-39 T 12-10-2018 TL08_26040 1467ac63e038a8f6a13ae8c7c715558d 285 SMART SM00641 80 189 1.5E-39 T 12-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup TL08_26040 1467ac63e038a8f6a13ae8c7c715558d 285 Pfam PF01183 Glycosyl hydrolases family 25 83 267 2.8E-48 T 12-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 TL08_26040 1467ac63e038a8f6a13ae8c7c715558d 285 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 84 117 - T 12-10-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 TL08_26040 1467ac63e038a8f6a13ae8c7c715558d 285 Gene3D G3DSA:3.20.20.80 77 285 9.7E-84 T 12-10-2018 TL08_26040 1467ac63e038a8f6a13ae8c7c715558d 285 SUPERFAMILY SSF51445 80 284 1.53E-64 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_23265 13ea4c5a97ccc741a87d6c87a026f660 228 Gene3D G3DSA:3.30.505.50 181 228 3.1E-18 T 12-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily TL08_23265 13ea4c5a97ccc741a87d6c87a026f660 228 SUPERFAMILY SSF69754 1 106 1.1E-25 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like TL08_23265 13ea4c5a97ccc741a87d6c87a026f660 228 Gene3D G3DSA:3.30.160.100 3 103 2.7E-24 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like TL08_23265 13ea4c5a97ccc741a87d6c87a026f660 228 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 168 223 4.9E-22 T 12-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal TL08_23265 13ea4c5a97ccc741a87d6c87a026f660 228 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 1.2E-28 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 TL08_23265 13ea4c5a97ccc741a87d6c87a026f660 228 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 227 23.18 T 12-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid TL08_23265 13ea4c5a97ccc741a87d6c87a026f660 228 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 99 3.3E-22 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 TL08_25220 0dbb395fc9bf5e395439b75b8b459572 277 Gene3D G3DSA:2.130.10.10 44 263 1.6E-9 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_25220 0dbb395fc9bf5e395439b75b8b459572 277 Pfam PF05096 Glutamine cyclotransferase 42 273 4.7E-96 T 12-10-2018 IPR007788 Glutaminyl-peptide cyclotransferase GO:0016603|GO:0017186 MetaCyc: PWY-7942 TL08_25220 0dbb395fc9bf5e395439b75b8b459572 277 SUPERFAMILY SSF50969 87 269 1.1E-13 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like TL08_26950 3ec44f698aabd5a65e2a0bba1526e471 174 Pfam PF08044 Domain of unknown function (DUF1707) 1 51 1.3E-15 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_00595 0f80bbbe76fa790e566178b472242d10 174 Pfam PF00011 Hsp20/alpha crystallin family 49 149 3.9E-14 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TL08_00595 0f80bbbe76fa790e566178b472242d10 174 Gene3D G3DSA:2.60.40.790 1 150 1.7E-29 T 12-10-2018 IPR008978 HSP20-like chaperone TL08_00595 0f80bbbe76fa790e566178b472242d10 174 SUPERFAMILY SSF49764 19 149 2.96E-27 T 12-10-2018 IPR008978 HSP20-like chaperone TL08_11860 399043717710e5ef1ba10b2b47695386 490 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 190 205 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site TL08_11860 399043717710e5ef1ba10b2b47695386 490 SUPERFAMILY SSF53474 17 488 3.49E-97 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_11860 399043717710e5ef1ba10b2b47695386 490 Gene3D G3DSA:3.40.50.1820 1 489 6.7E-113 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_11860 399043717710e5ef1ba10b2b47695386 490 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 119 135 - T 12-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 TL08_11860 399043717710e5ef1ba10b2b47695386 490 Pfam PF00135 Carboxylesterase family 18 474 1.6E-82 T 12-10-2018 IPR002018 Carboxylesterase, type B TL08_12765 ff0c4cf56cf007243f494254af3605b1 828 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 153 374 3.7E-52 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 TL08_12765 ff0c4cf56cf007243f494254af3605b1 828 SUPERFAMILY SSF51679 7 373 3.93E-66 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_12765 ff0c4cf56cf007243f494254af3605b1 828 SUPERFAMILY SSF51679 424 793 3.66E-79 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_12765 ff0c4cf56cf007243f494254af3605b1 828 Pfam PF00296 Luciferase-like monooxygenase 450 707 2.3E-40 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_12765 ff0c4cf56cf007243f494254af3605b1 828 Pfam PF00296 Luciferase-like monooxygenase 22 345 1.3E-32 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_12765 ff0c4cf56cf007243f494254af3605b1 828 Gene3D G3DSA:3.20.20.30 418 808 2.4E-112 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_02270 8f6a439ee8679b4603a3dee75e291fb7 406 Gene3D G3DSA:2.40.440.10 258 393 6.8E-83 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TL08_02270 8f6a439ee8679b4603a3dee75e291fb7 406 SUPERFAMILY SSF141523 255 377 5.49E-21 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like TL08_02270 8f6a439ee8679b4603a3dee75e291fb7 406 Gene3D G3DSA:2.60.40.3710 161 405 6.8E-83 T 12-10-2018 TL08_02270 8f6a439ee8679b4603a3dee75e291fb7 406 Pfam PF03734 L,D-transpeptidase catalytic domain 258 377 7.7E-15 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 TL08_02270 8f6a439ee8679b4603a3dee75e291fb7 406 Gene3D G3DSA:2.60.40.3780 55 151 1.1E-23 T 12-10-2018 TL08_12980 bdefcbf6e5d6f77c55fea2a6fac504e9 305 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 11 290 9.7E-57 T 12-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C TL08_12980 bdefcbf6e5d6f77c55fea2a6fac504e9 305 TIGRFAM TIGR02589 cas_Csd2: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG 11 303 6.7E-73 T 12-10-2018 IPR013418 CRISPR-associated protein Csd2 TL08_12980 bdefcbf6e5d6f77c55fea2a6fac504e9 305 Pfam PF05107 CRISPR-associated protein Cas7 11 290 2.6E-74 T 12-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C TL08_10780 74c9e9ab51e3fd6fde1ea42c6fab2b26 381 Pfam PF13531 Bacterial extracellular solute-binding protein 41 337 4.6E-21 T 12-10-2018 TL08_10780 74c9e9ab51e3fd6fde1ea42c6fab2b26 381 SUPERFAMILY SSF53850 38 338 4.03E-7 T 12-10-2018 TL08_16020 358e3effbf5e8833db270b2819e55c69 65 SUPERFAMILY SSF54862 2 62 3.54E-16 T 12-10-2018 TL08_16020 358e3effbf5e8833db270b2819e55c69 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 1.0E-14 T 12-10-2018 TL08_16020 358e3effbf5e8833db270b2819e55c69 65 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.0E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_16020 358e3effbf5e8833db270b2819e55c69 65 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.0E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_16020 358e3effbf5e8833db270b2819e55c69 65 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.0E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TL08_16020 358e3effbf5e8833db270b2819e55c69 65 Gene3D G3DSA:3.30.70.20 1 64 4.3E-22 T 12-10-2018 TL08_04015 7f3358d26b1d33fc9f720401f2890222 99 Gene3D G3DSA:1.10.287.1060 1 96 9.4E-7 T 12-10-2018 TL08_04015 7f3358d26b1d33fc9f720401f2890222 99 SUPERFAMILY SSF140453 5 96 8.24E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_20920 072e0b3df706e24d514b97c26e43e6f6 345 Pfam PF04235 Protein of unknown function (DUF418) 195 332 2.4E-29 T 12-10-2018 IPR007349 Domain of unknown function DUF418 TL08_16680 5f2823498d7449677193ad612e072382 72 Pfam PF07729 FCD domain 10 57 4.1E-6 T 12-10-2018 IPR011711 GntR, C-terminal TL08_16680 5f2823498d7449677193ad612e072382 72 SUPERFAMILY SSF48008 10 61 1.52E-7 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_16680 5f2823498d7449677193ad612e072382 72 Gene3D G3DSA:1.20.120.530 2 68 3.0E-8 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TL08_03255 b48dd8e55793d9997c77809fdadca2b5 217 SMART SM00858 57 119 2.0E-6 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 TL08_17560 3c4c14808d139cb4e53928a5faca2a82 710 SMART SM00382 489 617 1.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_17560 3c4c14808d139cb4e53928a5faca2a82 710 SUPERFAMILY SSF52540 445 667 1.49E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17560 3c4c14808d139cb4e53928a5faca2a82 710 Gene3D G3DSA:3.40.50.300 437 631 2.4E-39 T 12-10-2018 TL08_17560 3c4c14808d139cb4e53928a5faca2a82 710 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 494 618 1.7E-23 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TL08_12825 d5c8fbfe80e4cf5aa040a3957a4bcf06 146 Pfam PF03259 Roadblock/LC7 domain 14 103 5.7E-20 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TL08_12825 d5c8fbfe80e4cf5aa040a3957a4bcf06 146 SMART SM00960 13 103 1.6E-29 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TL08_12825 d5c8fbfe80e4cf5aa040a3957a4bcf06 146 SUPERFAMILY SSF103196 6 131 1.26E-29 T 12-10-2018 TL08_12825 d5c8fbfe80e4cf5aa040a3957a4bcf06 146 Gene3D G3DSA:3.30.450.30 9 134 3.3E-39 T 12-10-2018 TL08_09385 c090a267082ec7648718157a794bc09e 149 Gene3D G3DSA:1.10.260.40 3 87 2.7E-15 T 12-10-2018 TL08_09385 c090a267082ec7648718157a794bc09e 149 SMART SM00530 12 67 1.2E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_09385 c090a267082ec7648718157a794bc09e 149 Pfam PF13560 Helix-turn-helix domain 8 65 1.6E-9 T 12-10-2018 TL08_09385 c090a267082ec7648718157a794bc09e 149 SUPERFAMILY SSF47413 4 71 6.48E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_08345 d0ed31ae70ea2831d7853deaf51dbde9 601 SMART SM00487 29 212 4.8E-12 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TL08_08345 d0ed31ae70ea2831d7853deaf51dbde9 601 Gene3D G3DSA:3.40.50.300 26 194 1.0E-21 T 12-10-2018 TL08_08345 d0ed31ae70ea2831d7853deaf51dbde9 601 Pfam PF04851 Type III restriction enzyme, res subunit 33 185 5.2E-13 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TL08_08345 d0ed31ae70ea2831d7853deaf51dbde9 601 SUPERFAMILY SSF52540 147 392 5.06E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08345 d0ed31ae70ea2831d7853deaf51dbde9 601 SUPERFAMILY SSF52540 31 189 3.24E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08345 d0ed31ae70ea2831d7853deaf51dbde9 601 Gene3D G3DSA:3.40.50.300 213 400 7.0E-11 T 12-10-2018 TL08_19080 64abede4ab20a26f544002604f716f21 308 SUPERFAMILY SSF53807 27 304 1.18E-68 T 12-10-2018 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00691 Adhesin B signature 30 51 1.5E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00691 Adhesin B signature 74 93 1.5E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00691 Adhesin B signature 239 256 1.5E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00691 Adhesin B signature 283 301 1.5E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00691 Adhesin B signature 188 205 1.5E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00690 Adhesin family signature 61 74 2.1E-23 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00690 Adhesin family signature 188 209 2.1E-23 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00690 Adhesin family signature 30 48 2.1E-23 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00690 Adhesin family signature 270 289 2.1E-23 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00690 Adhesin family signature 74 91 2.1E-23 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 PRINTS PR00690 Adhesin family signature 243 261 2.1E-23 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TL08_19080 64abede4ab20a26f544002604f716f21 308 Gene3D G3DSA:3.40.50.1980 29 189 4.4E-37 T 12-10-2018 TL08_19080 64abede4ab20a26f544002604f716f21 308 Gene3D G3DSA:3.40.50.1980 190 308 1.5E-32 T 12-10-2018 TL08_19080 64abede4ab20a26f544002604f716f21 308 Pfam PF01297 Zinc-uptake complex component A periplasmic 33 302 1.5E-68 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TL08_09225 d0dff1f4aba7eedec6ee00d1cbd4add1 450 Pfam PF07690 Major Facilitator Superfamily 19 371 4.2E-39 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_09225 d0dff1f4aba7eedec6ee00d1cbd4add1 450 Gene3D G3DSA:1.20.1250.20 217 417 1.8E-15 T 12-10-2018 TL08_09225 d0dff1f4aba7eedec6ee00d1cbd4add1 450 SUPERFAMILY SSF103473 5 417 4.84E-55 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_09225 d0dff1f4aba7eedec6ee00d1cbd4add1 450 Gene3D G3DSA:1.20.1250.20 3 198 2.4E-32 T 12-10-2018 TL08_19775 62f40b85b2abdfac6946cd2ce4d65caa 329 Gene3D G3DSA:3.20.20.100 10 325 1.4E-110 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_19775 62f40b85b2abdfac6946cd2ce4d65caa 329 Pfam PF00248 Aldo/keto reductase family 23 321 2.7E-73 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_19775 62f40b85b2abdfac6946cd2ce4d65caa 329 SUPERFAMILY SSF51430 11 321 5.5E-98 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_05255 824e08b6697021763f4da9231cce0e65 340 SUPERFAMILY SSF50129 14 147 2.28E-22 T 12-10-2018 IPR011032 GroES-like superfamily TL08_05255 824e08b6697021763f4da9231cce0e65 340 Gene3D G3DSA:3.90.180.10 32 327 3.3E-49 T 12-10-2018 TL08_05255 824e08b6697021763f4da9231cce0e65 340 Pfam PF00107 Zinc-binding dehydrogenase 162 248 2.4E-15 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_05255 824e08b6697021763f4da9231cce0e65 340 SUPERFAMILY SSF51735 125 302 3.82E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05255 824e08b6697021763f4da9231cce0e65 340 Gene3D G3DSA:3.40.50.720 136 281 3.3E-49 T 12-10-2018 TL08_05255 824e08b6697021763f4da9231cce0e65 340 SMART SM00829 22 335 1.5E-9 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 SMART SM00421 150 207 1.7E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 SMART SM00448 8 121 1.1E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 SUPERFAMILY SSF52172 7 125 1.34E-28 T 12-10-2018 IPR011006 CheY-like superfamily TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 1.0E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 Gene3D G3DSA:3.40.50.12740 8 213 2.6E-57 T 12-10-2018 TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 Pfam PF00072 Response regulator receiver domain 10 122 3.5E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_24075 67b92f355b8cf97ba03b474acfeba3fd 217 SUPERFAMILY SSF46894 148 213 1.29E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_08935 506397aa1323e0b591df0fc9251f6230 94 Pfam PF04226 Transglycosylase associated protein 34 82 1.2E-12 T 12-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 TL08_17145 01356174c21216b4009039d3bed6f056 358 Gene3D G3DSA:3.40.50.1980 180 354 1.9E-42 T 12-10-2018 TL08_17145 01356174c21216b4009039d3bed6f056 358 Pfam PF01497 Periplasmic binding protein 88 321 5.8E-18 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TL08_17145 01356174c21216b4009039d3bed6f056 358 Gene3D G3DSA:3.40.50.1980 66 178 3.2E-23 T 12-10-2018 TL08_17145 01356174c21216b4009039d3bed6f056 358 SUPERFAMILY SSF53807 70 347 2.59E-52 T 12-10-2018 TL08_07535 4c644a15bb12372cfa70778b74881fb4 208 SUPERFAMILY SSF51735 1 198 1.44E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_07535 4c644a15bb12372cfa70778b74881fb4 208 Gene3D G3DSA:3.40.50.720 1 203 1.4E-48 T 12-10-2018 TL08_07535 4c644a15bb12372cfa70778b74881fb4 208 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 96 4.4E-13 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TL08_13905 861466e19a7260ad8ef24993c4d7dcc3 551 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 27 518 15.88 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 TL08_13905 861466e19a7260ad8ef24993c4d7dcc3 551 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 74 480 8.4E-77 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 TL08_13905 861466e19a7260ad8ef24993c4d7dcc3 551 SUPERFAMILY SSF56317 239 510 1.57E-38 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TL08_13905 861466e19a7260ad8ef24993c4d7dcc3 551 Pfam PF00795 Carbon-nitrogen hydrolase 244 504 3.6E-16 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TL08_13905 861466e19a7260ad8ef24993c4d7dcc3 551 Gene3D G3DSA:3.60.110.10 256 509 1.0E-16 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TL08_01330 9a2c6a8116c985ede80ea7a021d66dd7 254 Pfam PF01925 Sulfite exporter TauE/SafE 2 110 1.4E-25 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TL08_01330 9a2c6a8116c985ede80ea7a021d66dd7 254 Pfam PF01925 Sulfite exporter TauE/SafE 132 244 3.5E-18 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TL08_10320 f0bf9015e62b7884c38b3ace081199a9 218 SMART SM00953 60 190 8.9E-5 T 12-10-2018 IPR014914 RES domain TL08_10320 f0bf9015e62b7884c38b3ace081199a9 218 Pfam PF08808 RES domain 32 195 5.3E-20 T 12-10-2018 IPR014914 RES domain TL08_26805 8b4295cd683f6cd28791f4f6998a5ceb 128 Pfam PF17249 Family of unknown function (DUF5318) 1 123 2.6E-66 T 12-10-2018 IPR035169 Protein of unknown function DUF5318 TL08_16700 d414ef6f71dcaf13e48ffe39b0b23b72 258 SUPERFAMILY SSF53474 5 257 1.63E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16700 d414ef6f71dcaf13e48ffe39b0b23b72 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 6.6E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16700 d414ef6f71dcaf13e48ffe39b0b23b72 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 6.6E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16700 d414ef6f71dcaf13e48ffe39b0b23b72 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 6.6E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16700 d414ef6f71dcaf13e48ffe39b0b23b72 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 6.6E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16700 d414ef6f71dcaf13e48ffe39b0b23b72 258 Gene3D G3DSA:3.40.50.1820 3 258 1.8E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16700 d414ef6f71dcaf13e48ffe39b0b23b72 258 Pfam PF00561 alpha/beta hydrolase fold 22 121 2.9E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_26070 0e507b05d73daaebeac43b5eea3188ed 254 Pfam PF14011 EspG family 9 245 3.1E-50 T 12-10-2018 IPR025734 EspG family TL08_14735 768a413a8ab63004f3b41e679674a237 225 SUPERFAMILY SSF48371 8 220 1.53E-60 T 12-10-2018 IPR016024 Armadillo-type fold TL08_14735 768a413a8ab63004f3b41e679674a237 225 Pfam PF08713 DNA alkylation repair enzyme 10 197 1.8E-21 T 12-10-2018 IPR014825 DNA alkylation repair enzyme TL08_09535 8da358abd98340424aa85040e35afcc0 236 Gene3D G3DSA:3.60.140.10 1 234 2.4E-74 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily TL08_09535 8da358abd98340424aa85040e35afcc0 236 SUPERFAMILY SSF64438 3 233 8.79E-72 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic TL08_09535 8da358abd98340424aa85040e35afcc0 236 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 14 232 3.1E-51 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase TL08_09535 8da358abd98340424aa85040e35afcc0 236 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 8 231 4.4E-70 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase TL08_07360 5ccd5282106c5b2b1b56e0842b894403 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 84 1.4E-25 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07360 5ccd5282106c5b2b1b56e0842b894403 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 84 1.0E-22 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07360 5ccd5282106c5b2b1b56e0842b894403 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 106 2.2E-22 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07360 5ccd5282106c5b2b1b56e0842b894403 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 116 17.286 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07360 5ccd5282106c5b2b1b56e0842b894403 121 Gene3D G3DSA:2.60.15.10 2 121 1.7E-26 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07360 5ccd5282106c5b2b1b56e0842b894403 121 SUPERFAMILY SSF51344 4 84 9.16E-21 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_05005 e93be67f45c8f477b44abd7c036d93c7 192 Gene3D G3DSA:2.170.270.10 22 143 3.5E-17 T 12-10-2018 TL08_05005 e93be67f45c8f477b44abd7c036d93c7 192 SUPERFAMILY SSF82199 22 139 1.83E-20 T 12-10-2018 TL08_05005 e93be67f45c8f477b44abd7c036d93c7 192 Pfam PF00856 SET domain 80 118 4.5E-9 T 12-10-2018 IPR001214 SET domain GO:0005515 TL08_05005 e93be67f45c8f477b44abd7c036d93c7 192 SMART SM00317 22 125 3.6E-7 T 12-10-2018 IPR001214 SET domain GO:0005515 TL08_20970 e6607d503bf1b1a72602636da5732807 483 Pfam PF13570 PQQ-like domain 336 373 2.7E-5 T 12-10-2018 IPR025666 Pyrrolo-quinoline quinone-like domain TL08_20970 e6607d503bf1b1a72602636da5732807 483 Gene3D G3DSA:2.20.140.10 14 84 6.7E-20 T 12-10-2018 IPR036930 WGR domain superfamily TL08_20970 e6607d503bf1b1a72602636da5732807 483 SUPERFAMILY SSF50998 103 374 4.08E-21 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TL08_20970 e6607d503bf1b1a72602636da5732807 483 SMART SM00773 10 82 1.3E-17 T 12-10-2018 IPR008893 WGR domain TL08_20970 e6607d503bf1b1a72602636da5732807 483 Pfam PF05406 WGR domain 13 79 1.1E-15 T 12-10-2018 IPR008893 WGR domain TL08_20970 e6607d503bf1b1a72602636da5732807 483 SUPERFAMILY SSF142921 20 77 9.42E-10 T 12-10-2018 IPR036930 WGR domain superfamily TL08_20970 e6607d503bf1b1a72602636da5732807 483 Pfam PF13360 PQQ-like domain 249 321 1.2E-4 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TL08_20970 e6607d503bf1b1a72602636da5732807 483 Gene3D G3DSA:2.40.128.630 275 379 2.1E-12 T 12-10-2018 TL08_20970 e6607d503bf1b1a72602636da5732807 483 Gene3D G3DSA:2.130.10.10 98 274 6.7E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_12585 6c60fafcc5163c0ae2bb5c5a466e7dd1 402 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 344 5.1E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_03675 c784636978eaa93016f6dc861094a054 756 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 129 445 4.4E-52 T 12-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 TL08_03675 c784636978eaa93016f6dc861094a054 756 Pfam PF00326 Prolyl oligopeptidase family 541 731 2.2E-40 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_03675 c784636978eaa93016f6dc861094a054 756 Gene3D G3DSA:2.140.10.30 97 471 1.7E-85 T 12-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily TL08_03675 c784636978eaa93016f6dc861094a054 756 Gene3D G3DSA:3.40.50.1820 473 730 3.7E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_03675 c784636978eaa93016f6dc861094a054 756 SUPERFAMILY SSF82171 131 478 2.75E-33 T 12-10-2018 TL08_03675 c784636978eaa93016f6dc861094a054 756 SUPERFAMILY SSF53474 476 731 1.4E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_03965 5be8281a5d0e0437d444b5cd0d021591 264 SMART SM00530 1 55 0.0013 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_03965 5be8281a5d0e0437d444b5cd0d021591 264 SUPERFAMILY SSF47413 2 55 1.45E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_03965 5be8281a5d0e0437d444b5cd0d021591 264 Pfam PF13560 Helix-turn-helix domain 2 58 2.0E-9 T 12-10-2018 TL08_03965 5be8281a5d0e0437d444b5cd0d021591 264 Gene3D G3DSA:1.10.260.40 1 61 9.1E-6 T 12-10-2018 TL08_04330 31106148ad456e754dbdd5d933001cf3 489 SMART SM00530 24 79 2.3E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_04330 31106148ad456e754dbdd5d933001cf3 489 Gene3D G3DSA:1.10.260.40 14 81 6.8E-20 T 12-10-2018 TL08_04330 31106148ad456e754dbdd5d933001cf3 489 Pfam PF06114 IrrE N-terminal-like domain 216 313 1.6E-10 T 12-10-2018 IPR010359 IrrE N-terminal-like domain TL08_04330 31106148ad456e754dbdd5d933001cf3 489 SUPERFAMILY SSF47413 18 84 5.35E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_04330 31106148ad456e754dbdd5d933001cf3 489 Pfam PF13560 Helix-turn-helix domain 21 79 6.2E-15 T 12-10-2018 TL08_22095 15e857e9ba975595277092d60ee7ca04 387 Gene3D G3DSA:3.40.640.10 60 276 6.3E-79 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_22095 15e857e9ba975595277092d60ee7ca04 387 SUPERFAMILY SSF53383 44 375 5.2E-56 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_22095 15e857e9ba975595277092d60ee7ca04 387 Pfam PF00155 Aminotransferase class I and II 50 372 1.4E-28 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_22095 15e857e9ba975595277092d60ee7ca04 387 Gene3D G3DSA:3.90.1150.10 48 372 6.3E-79 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_22095 15e857e9ba975595277092d60ee7ca04 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 228 241 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 2.7E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 2.7E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 2.7E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 Pfam PF12146 Serine aminopeptidase, S33 205 255 1.1E-6 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 PRINTS PR00412 Epoxide hydrolase signature 214 230 9.9E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 PRINTS PR00412 Epoxide hydrolase signature 47 62 9.9E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 PRINTS PR00412 Epoxide hydrolase signature 27 45 9.9E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 Gene3D G3DSA:3.40.50.1820 2 274 2.7E-80 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 SUPERFAMILY SSF53474 2 274 9.76E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14180 ee4486d29d7ca1dc497e9cb8fd3dd3a7 275 Pfam PF00561 alpha/beta hydrolase fold 22 161 1.4E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_10275 822ae49629352b1536ec0e772f12e7e9 174 PIRSF PIRSF012622 8 174 1.4E-52 T 12-10-2018 IPR014465 Uncharacterised conserved protein UCP012622 TL08_10275 822ae49629352b1536ec0e772f12e7e9 174 SUPERFAMILY SSF159234 11 173 2.35E-41 T 12-10-2018 IPR035930 FomD-like superfamily TL08_10275 822ae49629352b1536ec0e772f12e7e9 174 Pfam PF04167 Protein of unknown function (DUF402) 60 127 2.7E-10 T 12-10-2018 IPR007295 Domain of unknown function DUF402 TL08_10275 822ae49629352b1536ec0e772f12e7e9 174 Gene3D G3DSA:2.40.380.10 4 172 7.3E-63 T 12-10-2018 IPR035930 FomD-like superfamily TL08_07415 591889d4f1c560b8a67d1481e6629556 559 Gene3D G3DSA:1.20.1730.10 34 527 1.4E-112 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily TL08_07415 591889d4f1c560b8a67d1481e6629556 559 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 45 458 5.8E-75 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TL08_07415 591889d4f1c560b8a67d1481e6629556 559 Pfam PF00474 Sodium:solute symporter family 45 458 1.7E-50 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TL08_07415 591889d4f1c560b8a67d1481e6629556 559 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 160 185 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site TL08_08500 d0adc7b8fb319249553fa93399a27ce8 626 SUPERFAMILY SSF52016 429 612 6.91E-55 T 12-10-2018 TL08_08500 d0adc7b8fb319249553fa93399a27ce8 626 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 12 612 1.0E-286 T 12-10-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 TL08_08500 d0adc7b8fb319249553fa93399a27ce8 626 Hamap MF_02094 Phosphogluconate dehydratase [edd]. 11 613 57.163 T 12-10-2018 TL08_08500 d0adc7b8fb319249553fa93399a27ce8 626 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 164 174 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_08500 d0adc7b8fb319249553fa93399a27ce8 626 Pfam PF00920 Dehydratase family 75 609 1.2E-161 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_08500 d0adc7b8fb319249553fa93399a27ce8 626 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 515 526 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_08500 d0adc7b8fb319249553fa93399a27ce8 626 Gene3D G3DSA:3.50.30.80 429 579 1.0E-50 T 12-10-2018 TL08_08500 d0adc7b8fb319249553fa93399a27ce8 626 SUPERFAMILY SSF143975 12 428 3.79E-145 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TL08_06375 a101c4e95ba3765ba907cf9463169abe 845 Pfam PF02687 FtsX-like permease family 748 838 9.7E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TL08_06375 a101c4e95ba3765ba907cf9463169abe 845 Pfam PF02687 FtsX-like permease family 289 381 1.9E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TL08_06375 a101c4e95ba3765ba907cf9463169abe 845 Pfam PF12704 MacB-like periplasmic core domain 19 226 2.0E-10 T 12-10-2018 IPR025857 MacB-like periplasmic core domain TL08_10070 e35f0d72e7b000823bf36f95eec883a5 184 Pfam PF00582 Universal stress protein family 37 170 4.2E-24 T 12-10-2018 IPR006016 UspA TL08_10070 e35f0d72e7b000823bf36f95eec883a5 184 PRINTS PR01438 Universal stress protein signature 35 53 2.3E-9 T 12-10-2018 IPR006015 Universal stress protein A TL08_10070 e35f0d72e7b000823bf36f95eec883a5 184 PRINTS PR01438 Universal stress protein signature 148 170 2.3E-9 T 12-10-2018 IPR006015 Universal stress protein A TL08_10070 e35f0d72e7b000823bf36f95eec883a5 184 PRINTS PR01438 Universal stress protein signature 130 142 2.3E-9 T 12-10-2018 IPR006015 Universal stress protein A TL08_10070 e35f0d72e7b000823bf36f95eec883a5 184 Gene3D G3DSA:3.40.50.620 26 175 1.7E-33 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_10070 e35f0d72e7b000823bf36f95eec883a5 184 SUPERFAMILY SSF52402 37 173 3.93E-26 T 12-10-2018 TL08_25310 ca4e1aff893e34716069baab31467f8b 208 Pfam PF05331 Protein of unknown function (DUF742) 97 208 2.6E-32 T 12-10-2018 IPR007995 Protein of unknown function DUF742 TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 Gene3D G3DSA:3.40.50.1820 1 258 2.9E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 7 22 3.0E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 78 3.0E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 64 3.0E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 PRINTS PR00412 Epoxide hydrolase signature 7 22 3.8E-16 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 PRINTS PR00412 Epoxide hydrolase signature 234 256 3.8E-16 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 PRINTS PR00412 Epoxide hydrolase signature 51 64 3.8E-16 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 PRINTS PR00412 Epoxide hydrolase signature 65 78 3.8E-16 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 Pfam PF00561 alpha/beta hydrolase fold 2 244 5.0E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_01315 17e8631dddaee34b5837e6b3d227a576 263 SUPERFAMILY SSF53474 2 258 9.16E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18385 3e8fa2f7455fca7481a50307f35f7f00 546 Gene3D G3DSA:3.60.21.70 118 458 2.2E-16 T 12-10-2018 IPR038607 PhoD-like superfamily TL08_18385 3e8fa2f7455fca7481a50307f35f7f00 546 SUPERFAMILY SSF56300 94 477 6.98E-12 T 12-10-2018 TL08_18385 3e8fa2f7455fca7481a50307f35f7f00 546 Pfam PF09423 PhoD-like phosphatase 121 459 2.6E-14 T 12-10-2018 IPR018946 Alkaline phosphatase D-related TL08_00125 07ea92f806e7c093f8f45b63a66ee0c1 496 PIRSF PIRSF000654 427 490 200.0 T 12-10-2018 TL08_00125 07ea92f806e7c093f8f45b63a66ee0c1 496 PIRSF PIRSF000654 17 264 6.9E-22 T 12-10-2018 TL08_00125 07ea92f806e7c093f8f45b63a66ee0c1 496 Pfam PF00069 Protein kinase domain 14 262 6.6E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_00125 07ea92f806e7c093f8f45b63a66ee0c1 496 SUPERFAMILY SSF56112 9 299 4.32E-72 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_00125 07ea92f806e7c093f8f45b63a66ee0c1 496 Gene3D G3DSA:3.30.200.20 2 98 8.4E-33 T 12-10-2018 TL08_00125 07ea92f806e7c093f8f45b63a66ee0c1 496 Gene3D G3DSA:1.10.510.10 100 280 2.2E-49 T 12-10-2018 TL08_00125 07ea92f806e7c093f8f45b63a66ee0c1 496 SMART SM00220 12 273 4.1E-54 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_00125 07ea92f806e7c093f8f45b63a66ee0c1 496 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_19330 37b36ab2cdb37ca05a171d794652a171 1091 SUPERFAMILY SSF52743 199 488 2.62E-75 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_19330 37b36ab2cdb37ca05a171d794652a171 1091 PRINTS PR00723 Subtilisin serine protease family (S8) signature 214 233 9.0E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_19330 37b36ab2cdb37ca05a171d794652a171 1091 PRINTS PR00723 Subtilisin serine protease family (S8) signature 428 444 9.0E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_19330 37b36ab2cdb37ca05a171d794652a171 1091 PRINTS PR00723 Subtilisin serine protease family (S8) signature 252 265 9.0E-19 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TL08_19330 37b36ab2cdb37ca05a171d794652a171 1091 Gene3D G3DSA:3.40.50.200 190 490 6.8E-88 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TL08_19330 37b36ab2cdb37ca05a171d794652a171 1091 Pfam PF00082 Subtilase family 214 477 6.4E-52 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TL08_19330 37b36ab2cdb37ca05a171d794652a171 1091 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 429 439 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TL08_19330 37b36ab2cdb37ca05a171d794652a171 1091 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 256 266 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TL08_23935 f57a9fb7391ec448fa68978f6f13b58b 218 Gene3D G3DSA:3.40.50.620 22 158 3.9E-14 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_23935 f57a9fb7391ec448fa68978f6f13b58b 218 Pfam PF02698 DUF218 domain 33 148 6.8E-20 T 12-10-2018 IPR003848 Domain of unknown function DUF218 TL08_12345 f0e884f7ca03cbd6f8c96ad7a4b9c599 340 Pfam PF01497 Periplasmic binding protein 71 295 6.6E-18 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TL08_12345 f0e884f7ca03cbd6f8c96ad7a4b9c599 340 Gene3D G3DSA:3.40.50.1980 186 340 8.1E-42 T 12-10-2018 TL08_12345 f0e884f7ca03cbd6f8c96ad7a4b9c599 340 SUPERFAMILY SSF53807 53 335 1.84E-45 T 12-10-2018 TL08_12345 f0e884f7ca03cbd6f8c96ad7a4b9c599 340 Gene3D G3DSA:3.40.50.1980 51 182 9.5E-38 T 12-10-2018 TL08_24110 432b6f6068bdc55fd7d6edcfe52ed729 421 Gene3D G3DSA:1.25.40.10 184 402 1.2E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_24110 432b6f6068bdc55fd7d6edcfe52ed729 421 SUPERFAMILY SSF47413 8 62 1.52E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_24110 432b6f6068bdc55fd7d6edcfe52ed729 421 Gene3D G3DSA:1.10.260.40 5 69 3.0E-9 T 12-10-2018 TL08_24110 432b6f6068bdc55fd7d6edcfe52ed729 421 Pfam PF13560 Helix-turn-helix domain 10 68 8.4E-11 T 12-10-2018 TL08_24110 432b6f6068bdc55fd7d6edcfe52ed729 421 SMART SM00530 13 68 1.4E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_17970 faec30a0276cc479963ce7c5ffd3b0f4 313 Gene3D G3DSA:3.40.50.300 57 313 4.7E-82 T 12-10-2018 TL08_17970 faec30a0276cc479963ce7c5ffd3b0f4 313 SUPERFAMILY SSF52540 62 312 6.21E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17970 faec30a0276cc479963ce7c5ffd3b0f4 313 Pfam PF13614 AAA domain 63 239 6.6E-59 T 12-10-2018 IPR025669 AAA domain TL08_15395 472a93f25d58471f038d32d1e980a1ce 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 285 7.3E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_15395 472a93f25d58471f038d32d1e980a1ce 292 SUPERFAMILY SSF161098 23 292 3.46E-63 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15395 472a93f25d58471f038d32d1e980a1ce 292 Gene3D G3DSA:1.10.3720.10 19 279 1.5E-51 T 12-10-2018 IPR035906 MetI-like superfamily TL08_20130 3e83b5f684c3fc13e7a4dcd2c3708194 237 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 115 223 5.3E-13 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 TL08_20130 3e83b5f684c3fc13e7a4dcd2c3708194 237 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 29 221 5.2E-18 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 TL08_20130 3e83b5f684c3fc13e7a4dcd2c3708194 237 Gene3D G3DSA:1.10.520.40 2 234 1.6E-20 T 12-10-2018 IPR038287 Cse2 superfamily TL08_16460 3277fc88bffaf57c3a983e21e2dc8fde 284 Gene3D G3DSA:2.60.120.260 138 282 4.5E-18 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_16460 3277fc88bffaf57c3a983e21e2dc8fde 284 SUPERFAMILY SSF49785 134 282 4.25E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_15895 dc0901fd0e2f7ba8ab9dd277dc3b035e 129 Gene3D G3DSA:3.10.180.10 2 127 5.8E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_15895 dc0901fd0e2f7ba8ab9dd277dc3b035e 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 119 5.5E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_15895 dc0901fd0e2f7ba8ab9dd277dc3b035e 129 SUPERFAMILY SSF54593 11 120 3.49E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03800 055b5cc6e2339702d7e4d79b719a8eb7 292 Gene3D G3DSA:3.40.470.10 48 278 8.9E-60 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_03800 055b5cc6e2339702d7e4d79b719a8eb7 292 SMART SM00986 91 269 6.4E-28 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_03800 055b5cc6e2339702d7e4d79b719a8eb7 292 SUPERFAMILY SSF52141 59 271 3.6E-39 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_03800 055b5cc6e2339702d7e4d79b719a8eb7 292 Pfam PF03167 Uracil DNA glycosylase superfamily 91 269 2.5E-24 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TL08_03800 055b5cc6e2339702d7e4d79b719a8eb7 292 SMART SM00987 91 269 6.4E-28 T 12-10-2018 TL08_02105 e942a8283bf0314c7b35b8e6603579a6 237 SUPERFAMILY SSF50494 67 230 1.06E-19 T 12-10-2018 IPR009003 Peptidase S1, PA clan TL08_02105 e942a8283bf0314c7b35b8e6603579a6 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 176 199 2.1E-34 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02105 e942a8283bf0314c7b35b8e6603579a6 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 80 94 2.1E-34 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02105 e942a8283bf0314c7b35b8e6603579a6 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 136 156 2.1E-34 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02105 e942a8283bf0314c7b35b8e6603579a6 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 157 174 2.1E-34 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02105 e942a8283bf0314c7b35b8e6603579a6 237 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 200 214 2.1E-34 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02105 e942a8283bf0314c7b35b8e6603579a6 237 PIRSF PIRSF001134 10 237 3.7E-54 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 TL08_02105 e942a8283bf0314c7b35b8e6603579a6 237 Gene3D G3DSA:2.40.10.10 124 222 1.1E-49 T 12-10-2018 TL08_02105 e942a8283bf0314c7b35b8e6603579a6 237 Gene3D G3DSA:2.40.10.10 61 233 1.1E-49 T 12-10-2018 TL08_01840 bd71362c2b7b2a63faade56f465117ae 285 Gene3D G3DSA:1.10.260.40 4 70 1.2E-8 T 12-10-2018 TL08_01840 bd71362c2b7b2a63faade56f465117ae 285 SMART SM00530 16 71 7.8E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_01840 bd71362c2b7b2a63faade56f465117ae 285 SUPERFAMILY SSF47413 10 68 2.48E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_01840 bd71362c2b7b2a63faade56f465117ae 285 Pfam PF13560 Helix-turn-helix domain 12 70 3.0E-10 T 12-10-2018 TL08_20335 f35ec2870bb758a7d2524ef344ec0090 144 Pfam PF07498 Rho termination factor, N-terminal domain 107 134 2.8E-5 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TL08_20335 f35ec2870bb758a7d2524ef344ec0090 144 Gene3D G3DSA:1.10.1740.70 8 70 9.8E-7 T 12-10-2018 TL08_20335 f35ec2870bb758a7d2524ef344ec0090 144 Pfam PF06150 ChaB 15 69 4.2E-17 T 12-10-2018 IPR009317 ChaB TL08_20335 f35ec2870bb758a7d2524ef344ec0090 144 SUPERFAMILY SSF140376 11 69 2.22E-14 T 12-10-2018 IPR037205 ChaB superfamily TL08_17890 470b52c7409a6a32c99d0567beea5f03 333 Pfam PF01497 Periplasmic binding protein 81 307 1.9E-29 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TL08_17890 470b52c7409a6a32c99d0567beea5f03 333 Gene3D G3DSA:3.40.50.1980 197 328 3.5E-35 T 12-10-2018 TL08_17890 470b52c7409a6a32c99d0567beea5f03 333 Gene3D G3DSA:3.40.50.1980 78 196 1.7E-26 T 12-10-2018 TL08_17890 470b52c7409a6a32c99d0567beea5f03 333 SUPERFAMILY SSF53807 72 327 3.41E-52 T 12-10-2018 TL08_11670 8e4aa8db726698bfae0677ddfb38cd77 135 Gene3D G3DSA:1.10.490.110 2 129 5.9E-16 T 12-10-2018 TL08_11670 8e4aa8db726698bfae0677ddfb38cd77 135 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 3 125 3.1E-33 T 12-10-2018 IPR018727 Protein of unknown function DUF2267 TL08_01170 9e78f758d6ea182bc25b8ce90b4c2e3e 164 Gene3D G3DSA:1.20.1260.10 3 164 4.7E-41 T 12-10-2018 IPR012347 Ferritin-like TL08_01170 9e78f758d6ea182bc25b8ce90b4c2e3e 164 Pfam PF00210 Ferritin-like domain 25 162 2.2E-20 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TL08_01170 9e78f758d6ea182bc25b8ce90b4c2e3e 164 PIRSF PIRSF005900 1 164 3.9E-41 T 12-10-2018 IPR002177 DNA-binding protein Dps TL08_01170 9e78f758d6ea182bc25b8ce90b4c2e3e 164 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 68 84 1.2E-11 T 12-10-2018 IPR002177 DNA-binding protein Dps TL08_01170 9e78f758d6ea182bc25b8ce90b4c2e3e 164 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 139 157 1.2E-11 T 12-10-2018 IPR002177 DNA-binding protein Dps TL08_01170 9e78f758d6ea182bc25b8ce90b4c2e3e 164 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 44 60 1.2E-11 T 12-10-2018 IPR002177 DNA-binding protein Dps TL08_01170 9e78f758d6ea182bc25b8ce90b4c2e3e 164 SUPERFAMILY SSF47240 11 160 2.82E-40 T 12-10-2018 IPR009078 Ferritin-like superfamily TL08_21950 b384f112a2402950443af4c4294c0de9 252 SUPERFAMILY SSF52317 20 191 2.52E-36 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_21950 b384f112a2402950443af4c4294c0de9 252 Pfam PF00117 Glutamine amidotransferase class-I 24 185 1.0E-16 T 12-10-2018 IPR017926 Glutamine amidotransferase TL08_21950 b384f112a2402950443af4c4294c0de9 252 Gene3D G3DSA:3.40.50.880 1 232 1.0E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_06325 5682720bebf52316038bea4944e87492 538 SUPERFAMILY SSF53850 32 325 3.33E-14 T 12-10-2018 TL08_06325 5682720bebf52316038bea4944e87492 538 Gene3D G3DSA:3.40.50.410 345 535 1.5E-26 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_06325 5682720bebf52316038bea4944e87492 538 Pfam PF00092 von Willebrand factor type A domain 349 531 1.5E-5 T 12-10-2018 IPR002035 von Willebrand factor, type A TL08_06325 5682720bebf52316038bea4944e87492 538 SUPERFAMILY SSF53300 346 535 2.54E-18 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_06325 5682720bebf52316038bea4944e87492 538 Pfam PF13531 Bacterial extracellular solute-binding protein 33 295 2.3E-19 T 12-10-2018 TL08_06480 d9d64a9bacd01f991fea5ad1fc55967f 186 Pfam PF09438 Domain of unknown function (DUF2017) 6 184 5.8E-60 T 12-10-2018 IPR018561 Domain of unknown function DUF2017 TL08_00765 caff9da68b3810bfcdef10a95e5f4695 407 Gene3D G3DSA:3.40.50.1820 40 395 4.8E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_00765 caff9da68b3810bfcdef10a95e5f4695 407 SUPERFAMILY SSF53474 69 284 1.0E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_00765 caff9da68b3810bfcdef10a95e5f4695 407 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 45 182 1.0E-9 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 TL08_00765 caff9da68b3810bfcdef10a95e5f4695 407 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 243 347 1.5E-4 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 TL08_09065 9c0bd0825ed885698588fb4ce22bba39 389 Gene3D G3DSA:1.20.1250.20 3 387 1.0E-46 T 12-10-2018 TL08_09065 9c0bd0825ed885698588fb4ce22bba39 389 SUPERFAMILY SSF103473 4 385 3.4E-57 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_09065 9c0bd0825ed885698588fb4ce22bba39 389 Pfam PF07690 Major Facilitator Superfamily 9 321 1.1E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_13030 4d77074dbf3f4a8d034b51bf14f46d75 270 PIRSF PIRSF017393 2 270 4.4E-78 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_13030 4d77074dbf3f4a8d034b51bf14f46d75 270 Pfam PF04672 S-adenosyl methyltransferase 14 268 1.4E-75 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_13030 4d77074dbf3f4a8d034b51bf14f46d75 270 Gene3D G3DSA:3.40.50.150 4 269 7.1E-85 T 12-10-2018 TL08_13030 4d77074dbf3f4a8d034b51bf14f46d75 270 SUPERFAMILY SSF53335 23 256 1.87E-35 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_17210 8ac985254b1c4ae1ab38f6b61d67eb7c 159 SUPERFAMILY SSF54593 5 120 1.1E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_17210 8ac985254b1c4ae1ab38f6b61d67eb7c 159 Gene3D G3DSA:3.10.180.10 1 123 1.8E-48 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_17210 8ac985254b1c4ae1ab38f6b61d67eb7c 159 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 93 1.8E-10 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_09410 257570f13d869abeb9dfc7216323d366 276 Gene3D G3DSA:3.40.50.300 1 270 4.9E-55 T 12-10-2018 TL08_09410 257570f13d869abeb9dfc7216323d366 276 Pfam PF13614 AAA domain 3 183 9.5E-29 T 12-10-2018 IPR025669 AAA domain TL08_09410 257570f13d869abeb9dfc7216323d366 276 SUPERFAMILY SSF52540 2 253 4.76E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13715 e3d3623c53e37f99c3ee2c19f10e95d9 341 SUPERFAMILY SSF53807 44 329 1.49E-48 T 12-10-2018 TL08_13715 e3d3623c53e37f99c3ee2c19f10e95d9 341 Gene3D G3DSA:3.40.50.1980 181 340 4.8E-38 T 12-10-2018 TL08_13715 e3d3623c53e37f99c3ee2c19f10e95d9 341 Gene3D G3DSA:3.40.50.1980 39 178 2.8E-39 T 12-10-2018 TL08_13715 e3d3623c53e37f99c3ee2c19f10e95d9 341 Pfam PF01497 Periplasmic binding protein 62 302 2.5E-22 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TL08_24230 c00cd51deb0296e9ac4adf530cce08d4 74 Pfam PF04149 Domain of unknown function (DUF397) 15 63 4.1E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_08405 afa22f4687a0b17214f6dbefcb56457b 180 Pfam PF11292 Protein of unknown function (DUF3093) 26 163 1.6E-48 T 12-10-2018 IPR021443 Protein of unknown function DUF3093 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 SUPERFAMILY SSF51445 317 648 3.29E-99 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 PRINTS PR00743 Glycosyl hydrolase family 36 signature 456 471 1.9E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 PRINTS PR00743 Glycosyl hydrolase family 36 signature 531 547 1.9E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 PRINTS PR00743 Glycosyl hydrolase family 36 signature 348 363 1.9E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 PRINTS PR00743 Glycosyl hydrolase family 36 signature 235 250 1.9E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 PRINTS PR00743 Glycosyl hydrolase family 36 signature 320 334 1.9E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 PRINTS PR00743 Glycosyl hydrolase family 36 signature 398 420 1.9E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 PRINTS PR00743 Glycosyl hydrolase family 36 signature 506 522 1.9E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 35 278 3.0E-40 T 12-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 PIRSF PIRSF005536 9 690 6.7E-173 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 Pfam PF02065 Melibiase 283 620 3.3E-120 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 Gene3D G3DSA:2.70.98.60 120 301 5.1E-30 T 12-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 Gene3D G3DSA:3.20.20.70 302 618 5.1E-124 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_15295 ee8e4b6ee7a71ac7efbd1649409caa93 733 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 637 716 6.0E-8 T 12-10-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TL08_18900 1e24e253b806ef36df4e3372a8114b7d 279 Gene3D G3DSA:3.40.50.300 14 266 4.6E-63 T 12-10-2018 TL08_18900 1e24e253b806ef36df4e3372a8114b7d 279 SUPERFAMILY SSF52540 16 243 4.98E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_18900 1e24e253b806ef36df4e3372a8114b7d 279 SMART SM00382 38 228 2.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_18900 1e24e253b806ef36df4e3372a8114b7d 279 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_18900 1e24e253b806ef36df4e3372a8114b7d 279 Pfam PF00005 ABC transporter 31 178 2.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_11015 37ed67a64809a03395198033b276a3d0 837 SUPERFAMILY SSF56112 381 710 1.75E-58 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_11015 37ed67a64809a03395198033b276a3d0 837 Gene3D G3DSA:3.30.200.20 360 465 9.2E-24 T 12-10-2018 TL08_11015 37ed67a64809a03395198033b276a3d0 837 Gene3D G3DSA:1.10.510.10 466 641 1.3E-32 T 12-10-2018 TL08_11015 37ed67a64809a03395198033b276a3d0 837 SMART SM00220 383 640 5.6E-42 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_11015 37ed67a64809a03395198033b276a3d0 837 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 503 515 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TL08_11015 37ed67a64809a03395198033b276a3d0 837 Pfam PF00069 Protein kinase domain 383 588 2.7E-42 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_11015 37ed67a64809a03395198033b276a3d0 837 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 389 412 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_26205 3e48406a9e9f31d1c5f81600c57b3114 95 SUPERFAMILY SSF54909 1 87 1.32E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_26205 3e48406a9e9f31d1c5f81600c57b3114 95 Pfam PF03795 YCII-related domain 15 85 2.3E-12 T 12-10-2018 IPR005545 YCII-related TL08_26205 3e48406a9e9f31d1c5f81600c57b3114 95 Gene3D G3DSA:3.30.70.1060 9 88 3.5E-13 T 12-10-2018 TL08_03925 556c2fcfe69846c3e33dbd9b438d522a 384 Gene3D G3DSA:3.20.20.120 105 350 1.7E-123 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_03925 556c2fcfe69846c3e33dbd9b438d522a 384 SUPERFAMILY SSF51604 99 365 5.37E-81 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_03925 556c2fcfe69846c3e33dbd9b438d522a 384 SMART SM00922 132 237 4.5E-22 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_03925 556c2fcfe69846c3e33dbd9b438d522a 384 Gene3D G3DSA:3.30.390.10 6 360 1.7E-123 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_03925 556c2fcfe69846c3e33dbd9b438d522a 384 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 111 6.3E-14 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TL08_03925 556c2fcfe69846c3e33dbd9b438d522a 384 SUPERFAMILY SSF54826 2 116 9.43E-27 T 12-10-2018 TL08_03925 556c2fcfe69846c3e33dbd9b438d522a 384 Pfam PF13378 Enolase C-terminal domain-like 138 357 5.4E-66 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_05855 384e8f2d8d5eac9b9511fc0de3742609 241 PIRSF PIRSF000706 1 241 6.7E-68 T 12-10-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 TL08_05855 384e8f2d8d5eac9b9511fc0de3742609 241 Gene3D G3DSA:3.90.1200.10 63 241 5.5E-58 T 12-10-2018 TL08_05855 384e8f2d8d5eac9b9511fc0de3742609 241 SUPERFAMILY SSF56112 1 240 1.95E-45 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_05855 384e8f2d8d5eac9b9511fc0de3742609 241 Gene3D G3DSA:3.30.200.20 1 62 7.7E-15 T 12-10-2018 TL08_05855 384e8f2d8d5eac9b9511fc0de3742609 241 Pfam PF01636 Phosphotransferase enzyme family 2 229 8.3E-33 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_15100 26f1653c9760c45309e97082fd9d2a3f 140 Gene3D G3DSA:3.10.180.10 3 133 4.6E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_15100 26f1653c9760c45309e97082fd9d2a3f 140 SUPERFAMILY SSF54593 7 134 1.29E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_15100 26f1653c9760c45309e97082fd9d2a3f 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 129 7.9E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_09990 f92b58019d39bc34ef8997f138165b0e 476 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 15 338 7.6E-88 T 12-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme TL08_09990 f92b58019d39bc34ef8997f138165b0e 476 Gene3D G3DSA:3.20.20.70 67 292 2.5E-29 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_09990 f92b58019d39bc34ef8997f138165b0e 476 Pfam PF04055 Radical SAM superfamily 88 236 1.5E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_09990 f92b58019d39bc34ef8997f138165b0e 476 SUPERFAMILY SSF102114 86 318 2.88E-26 T 12-10-2018 TL08_08330 4ba16f56ebefbbdd2d3aff83c41438aa 308 Pfam PF00294 pfkB family carbohydrate kinase 7 301 4.4E-52 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_08330 4ba16f56ebefbbdd2d3aff83c41438aa 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 256 269 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TL08_08330 4ba16f56ebefbbdd2d3aff83c41438aa 308 Gene3D G3DSA:3.40.1190.20 5 305 2.5E-67 T 12-10-2018 IPR029056 Ribokinase-like TL08_08330 4ba16f56ebefbbdd2d3aff83c41438aa 308 SUPERFAMILY SSF53613 6 301 6.24E-66 T 12-10-2018 IPR029056 Ribokinase-like TL08_17225 3f05c3ae732a91cbcce1bc82b0c54b17 138 SMART SM00226 5 130 2.8E-41 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TL08_17225 3f05c3ae732a91cbcce1bc82b0c54b17 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 128 2.4E-22 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TL08_17225 3f05c3ae732a91cbcce1bc82b0c54b17 138 Gene3D G3DSA:3.40.50.2300 4 134 1.6E-50 T 12-10-2018 TL08_17225 3f05c3ae732a91cbcce1bc82b0c54b17 138 SUPERFAMILY SSF52788 5 128 1.44E-35 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 Pfam PF10397 Adenylosuccinate lyase C-terminus 370 454 3.1E-12 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 SUPERFAMILY SSF48557 11 456 9.27E-81 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 11 454 7.2E-126 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 1.2E-9 T 12-10-2018 IPR000362 Fumarate lyase family TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 1.2E-9 T 12-10-2018 IPR000362 Fumarate lyase family TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 1.2E-9 T 12-10-2018 IPR000362 Fumarate lyase family TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 Gene3D G3DSA:1.10.40.30 367 443 1.8E-142 T 12-10-2018 TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 Gene3D G3DSA:1.10.275.60 25 234 1.8E-142 T 12-10-2018 TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 Gene3D G3DSA:1.20.200.10 14 452 1.8E-142 T 12-10-2018 TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 SMART SM00998 369 455 1.6E-22 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TL08_26080 d27281c326aca08189f5adc9af10cfe3 477 Pfam PF00206 Lyase 36 304 5.7E-23 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal TL08_05815 c5bbf61eb4e859eba43b00eb223587c0 327 Gene3D G3DSA:3.40.50.720 7 325 1.1E-50 T 12-10-2018 TL08_05815 c5bbf61eb4e859eba43b00eb223587c0 327 SUPERFAMILY SSF51735 5 324 4.63E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05815 c5bbf61eb4e859eba43b00eb223587c0 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 248 6.5E-34 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_04375 bbd14215ac3da5f0ac078ad3ff990b5a 355 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 38 349 1.2E-68 T 12-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 TL08_04375 bbd14215ac3da5f0ac078ad3ff990b5a 355 Gene3D G3DSA:3.40.190.10 141 350 5.1E-102 T 12-10-2018 TL08_04375 bbd14215ac3da5f0ac078ad3ff990b5a 355 Pfam PF13343 Bacterial extracellular solute-binding protein 89 325 1.8E-25 T 12-10-2018 TL08_04375 bbd14215ac3da5f0ac078ad3ff990b5a 355 Gene3D G3DSA:3.40.190.10 44 324 5.1E-102 T 12-10-2018 TL08_04375 bbd14215ac3da5f0ac078ad3ff990b5a 355 SUPERFAMILY SSF53850 42 350 3.71E-49 T 12-10-2018 TL08_13845 70caff3f3173b52527b2e7ab67adf958 269 Gene3D G3DSA:3.40.50.150 57 215 2.6E-17 T 12-10-2018 TL08_13845 70caff3f3173b52527b2e7ab67adf958 269 SUPERFAMILY SSF53335 49 268 2.15E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13845 70caff3f3173b52527b2e7ab67adf958 269 Pfam PF08241 Methyltransferase domain 72 158 5.3E-11 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 Gene3D G3DSA:3.30.565.10 228 383 1.2E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 SMART SM00387 269 377 1.1E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 Gene3D G3DSA:1.10.287.130 111 227 5.1E-23 T 12-10-2018 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 374 4.0E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 317 4.0E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 337 355 4.0E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 331 4.0E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 SMART SM00304 107 160 5.4E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 SUPERFAMILY SSF47384 145 226 4.71E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 271 375 1.0E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 SUPERFAMILY SSF158472 108 157 2.88E-5 T 12-10-2018 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 Pfam PF00512 His Kinase A (phospho-acceptor) domain 162 225 7.3E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 SMART SM00388 161 226 4.9E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TL08_07745 1e27b59d1858eefad19ce4373c1442bc 387 SUPERFAMILY SSF55874 215 375 1.28E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_19735 ef0a1e96252c1e33049da11e6009028f 429 SUPERFAMILY SSF54826 10 142 4.24E-26 T 12-10-2018 TL08_19735 ef0a1e96252c1e33049da11e6009028f 429 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 41 142 8.9E-6 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TL08_19735 ef0a1e96252c1e33049da11e6009028f 429 SUPERFAMILY SSF51604 142 401 2.4E-71 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_19735 ef0a1e96252c1e33049da11e6009028f 429 Gene3D G3DSA:3.20.20.120 142 385 2.7E-188 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TL08_19735 ef0a1e96252c1e33049da11e6009028f 429 Gene3D G3DSA:3.30.390.10 12 422 2.7E-188 T 12-10-2018 IPR029017 Enolase-like, N-terminal TL08_19735 ef0a1e96252c1e33049da11e6009028f 429 Pfam PF13378 Enolase C-terminal domain-like 179 392 1.0E-49 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TL08_19735 ef0a1e96252c1e33049da11e6009028f 429 SMART SM00922 176 270 7.5E-24 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TL08_22190 29d5aa88c80be2e69d96450f755616a9 210 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 17 199 4.0E-14 T 12-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 TL08_22190 29d5aa88c80be2e69d96450f755616a9 210 Pfam PF04973 Nicotinamide mononucleotide transporter 17 196 1.7E-44 T 12-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 Pfam PF00067 Cytochrome P450 217 371 2.2E-21 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00385 P450 superfamily signature 240 257 8.9E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00385 P450 superfamily signature 275 286 8.9E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00385 P450 superfamily signature 341 350 8.9E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00385 P450 superfamily signature 350 361 8.9E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00359 B-class P450 signature 97 108 1.4E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00359 B-class P450 signature 275 286 1.4E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00359 B-class P450 signature 341 350 1.4E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00359 B-class P450 signature 198 220 1.4E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00359 B-class P450 signature 161 176 1.4E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00359 B-class P450 signature 292 319 1.4E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00359 B-class P450 signature 350 361 1.4E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00359 B-class P450 signature 320 335 1.4E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 PRINTS PR00359 B-class P450 signature 144 160 1.4E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 SUPERFAMILY SSF48264 14 402 1.96E-97 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_18780 6ef123eafc8e951c49a04d94e937ed90 406 Gene3D G3DSA:1.10.630.10 12 406 3.7E-121 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_19730 e78741ffcd1d1fd933dfde9a4a21227b 329 SUPERFAMILY SSF51735 97 294 3.03E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19730 e78741ffcd1d1fd933dfde9a4a21227b 329 Gene3D G3DSA:3.40.50.720 11 318 4.3E-77 T 12-10-2018 TL08_19730 e78741ffcd1d1fd933dfde9a4a21227b 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 293 1.4E-46 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TL08_19730 e78741ffcd1d1fd933dfde9a4a21227b 329 Gene3D G3DSA:3.40.50.720 95 292 4.3E-77 T 12-10-2018 TL08_19730 e78741ffcd1d1fd933dfde9a4a21227b 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 25 325 1.4E-12 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TL08_19730 e78741ffcd1d1fd933dfde9a4a21227b 329 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 227 243 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TL08_19730 e78741ffcd1d1fd933dfde9a4a21227b 329 SUPERFAMILY SSF52283 1 128 1.02E-18 T 12-10-2018 TL08_07065 23ee008179e1a8e915eb431c36c59c49 309 Gene3D G3DSA:3.40.50.1820 12 299 3.4E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07065 23ee008179e1a8e915eb431c36c59c49 309 SUPERFAMILY SSF53474 33 297 1.97E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07065 23ee008179e1a8e915eb431c36c59c49 309 Pfam PF12697 Alpha/beta hydrolase family 70 291 5.0E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_17555 086f7cf680e6f50184ff9d4f32d94834 301 SUPERFAMILY SSF46785 7 112 5.0E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17555 086f7cf680e6f50184ff9d4f32d94834 301 Gene3D G3DSA:3.40.190.290 90 296 4.3E-75 T 12-10-2018 TL08_17555 086f7cf680e6f50184ff9d4f32d94834 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 3.3E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_17555 086f7cf680e6f50184ff9d4f32d94834 301 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 6 296 1.3E-100 T 12-10-2018 IPR017685 HTH-type transcriptional regulator ArgP TL08_17555 086f7cf680e6f50184ff9d4f32d94834 301 SUPERFAMILY SSF53850 92 292 6.7E-17 T 12-10-2018 TL08_17555 086f7cf680e6f50184ff9d4f32d94834 301 Pfam PF03466 LysR substrate binding domain 121 291 5.3E-12 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_17555 086f7cf680e6f50184ff9d4f32d94834 301 Gene3D G3DSA:1.10.10.10 1 85 9.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16400 deb69a6a16f37a4e4bd492483b5f780d 223 SUPERFAMILY SSF53335 3 144 1.06E-20 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_16400 deb69a6a16f37a4e4bd492483b5f780d 223 Gene3D G3DSA:3.40.50.150 1 207 8.0E-68 T 12-10-2018 TL08_13285 8d6938419a86c2fef64531686a809703 220 SMART SM01007 6 188 1.7E-54 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TL08_13285 8d6938419a86c2fef64531686a809703 220 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 187 1.1E-43 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TL08_13285 8d6938419a86c2fef64531686a809703 220 Gene3D G3DSA:3.40.225.10 2 213 1.7E-55 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TL08_13285 8d6938419a86c2fef64531686a809703 220 SUPERFAMILY SSF53639 3 214 1.0E-53 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TL08_12010 e8333826a54c4d21e56e00aa9f52f598 297 Pfam PF12705 PD-(D/E)XK nuclease superfamily 24 270 2.9E-37 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TL08_12010 e8333826a54c4d21e56e00aa9f52f598 297 Gene3D G3DSA:3.90.320.10 18 252 1.3E-6 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TL08_12010 e8333826a54c4d21e56e00aa9f52f598 297 SUPERFAMILY SSF52980 44 205 1.66E-9 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TL08_21190 6e562564fb7143ca40fd5106fbf8ebe0 306 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_21190 6e562564fb7143ca40fd5106fbf8ebe0 306 SUPERFAMILY SSF52540 3 235 6.38E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21190 6e562564fb7143ca40fd5106fbf8ebe0 306 SMART SM00382 28 205 2.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_21190 6e562564fb7143ca40fd5106fbf8ebe0 306 Pfam PF00005 ABC transporter 20 157 7.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_21190 6e562564fb7143ca40fd5106fbf8ebe0 306 Gene3D G3DSA:3.40.50.300 1 226 9.9E-61 T 12-10-2018 TL08_05410 cfac4783ac4384489ad25f0b771dc7f1 555 SUPERFAMILY SSF53474 167 539 1.28E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05410 cfac4783ac4384489ad25f0b771dc7f1 555 Pfam PF00561 alpha/beta hydrolase fold 139 526 9.2E-42 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_20355 1c9e836279796b2ba8867502e45cee9e 190 Pfam PF01965 DJ-1/PfpI family 9 176 1.0E-51 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TL08_20355 1c9e836279796b2ba8867502e45cee9e 190 SUPERFAMILY SSF52317 8 178 2.07E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_20355 1c9e836279796b2ba8867502e45cee9e 190 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 13 175 2.0E-44 T 12-10-2018 IPR006286 Deglycase PfpI TL08_20355 1c9e836279796b2ba8867502e45cee9e 190 Gene3D G3DSA:3.40.50.880 2 187 3.7E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_26250 58d2aa8ba9434f3701e5ead905b95799 413 SUPERFAMILY SSF55874 292 406 3.3E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_26250 58d2aa8ba9434f3701e5ead905b95799 413 Pfam PF07730 Histidine kinase 199 264 4.2E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_26250 58d2aa8ba9434f3701e5ead905b95799 413 Gene3D G3DSA:3.30.565.10 276 405 4.5E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_25900 fd459a107cc92f9402c294a3ff2a0bcf 369 Pfam PF12849 PBP superfamily domain 45 335 1.9E-57 T 12-10-2018 IPR024370 PBP domain TL08_25900 fd459a107cc92f9402c294a3ff2a0bcf 369 PIRSF PIRSF002756 6 369 1.3E-107 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TL08_25900 fd459a107cc92f9402c294a3ff2a0bcf 369 Gene3D G3DSA:3.40.190.10 57 355 1.9E-104 T 12-10-2018 TL08_25900 fd459a107cc92f9402c294a3ff2a0bcf 369 Gene3D G3DSA:3.40.190.10 134 310 1.9E-104 T 12-10-2018 TL08_25900 fd459a107cc92f9402c294a3ff2a0bcf 369 SUPERFAMILY SSF53850 53 368 2.04E-79 T 12-10-2018 TL08_25900 fd459a107cc92f9402c294a3ff2a0bcf 369 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 55 367 3.4E-84 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TL08_13760 cb3703d6ee3ceddf5b5219a8a06d1340 334 SUPERFAMILY SSF54593 6 282 1.79E-48 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_13760 cb3703d6ee3ceddf5b5219a8a06d1340 334 Gene3D G3DSA:3.10.180.10 7 307 4.8E-113 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_13760 cb3703d6ee3ceddf5b5219a8a06d1340 334 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 154 270 6.6E-14 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_13760 cb3703d6ee3ceddf5b5219a8a06d1340 334 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 125 3.5E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_13760 cb3703d6ee3ceddf5b5219a8a06d1340 334 Gene3D G3DSA:3.10.180.10 67 214 4.8E-113 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_10050 fb4268ab8d5b9dafed3f4e5eedf74234 327 SUPERFAMILY SSF51430 1 318 6.29E-73 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_10050 fb4268ab8d5b9dafed3f4e5eedf74234 327 Gene3D G3DSA:3.20.20.100 1 323 2.1E-77 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_10050 fb4268ab8d5b9dafed3f4e5eedf74234 327 Pfam PF00248 Aldo/keto reductase family 16 315 1.6E-57 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_16910 df60d971837e0f964e832ba3656840b6 398 Gene3D G3DSA:2.130.10.10 58 398 2.5E-109 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_16910 df60d971837e0f964e832ba3656840b6 398 SUPERFAMILY SSF51004 80 397 1.57E-51 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily TL08_16910 df60d971837e0f964e832ba3656840b6 398 Pfam PF10282 Lactonase, 7-bladed beta-propeller 62 395 2.5E-98 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller TL08_06500 3ff5067d7180d4e03fdcc529c1c31854 316 Gene3D G3DSA:3.40.50.1100 8 295 5.2E-102 T 12-10-2018 TL08_06500 3ff5067d7180d4e03fdcc529c1c31854 316 SUPERFAMILY SSF53686 2 298 4.85E-86 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_06500 3ff5067d7180d4e03fdcc529c1c31854 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 TL08_06500 3ff5067d7180d4e03fdcc529c1c31854 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 299 2.3E-109 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 TL08_06500 3ff5067d7180d4e03fdcc529c1c31854 316 Gene3D G3DSA:3.40.50.1100 40 159 5.2E-102 T 12-10-2018 TL08_06500 3ff5067d7180d4e03fdcc529c1c31854 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 287 8.8E-67 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_06760 a1477e99d795fa6667ab94e029af2743 317 Gene3D G3DSA:3.90.1200.10 118 289 4.0E-12 T 12-10-2018 TL08_06760 a1477e99d795fa6667ab94e029af2743 317 SUPERFAMILY SSF56112 54 284 4.25E-27 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_06760 a1477e99d795fa6667ab94e029af2743 317 PIRSF PIRSF000707 1 317 1.9E-91 T 12-10-2018 IPR016259 Hygromycin-B kinase TL08_06760 a1477e99d795fa6667ab94e029af2743 317 Pfam PF01636 Phosphotransferase enzyme family 52 265 2.4E-23 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_24145 bcf61d1f6705f08144aa9ddb76a0652b 155 PIRSF PIRSF018072 1 149 2.5E-38 T 12-10-2018 IPR016709 Uncharacterised protein family UPF0336 TL08_24145 bcf61d1f6705f08144aa9ddb76a0652b 155 Pfam PF13452 N-terminal half of MaoC dehydratase 14 137 3.5E-24 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 TL08_24145 bcf61d1f6705f08144aa9ddb76a0652b 155 Gene3D G3DSA:3.10.129.10 2 149 4.3E-34 T 12-10-2018 TL08_24145 bcf61d1f6705f08144aa9ddb76a0652b 155 SUPERFAMILY SSF54637 13 146 7.64E-28 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_19935 7e93746b6a6b2a3a2fc62fa2eb0dbd6a 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19935 7e93746b6a6b2a3a2fc62fa2eb0dbd6a 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19935 7e93746b6a6b2a3a2fc62fa2eb0dbd6a 236 SUPERFAMILY SSF46689 11 74 1.9E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_19935 7e93746b6a6b2a3a2fc62fa2eb0dbd6a 236 Gene3D G3DSA:1.10.357.10 7 202 2.4E-21 T 12-10-2018 TL08_19935 7e93746b6a6b2a3a2fc62fa2eb0dbd6a 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 5.6E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_05440 d6e00e4ca772b6699866b7b4f48d9bc5 340 SMART SM00829 7 338 0.0043 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_05440 d6e00e4ca772b6699866b7b4f48d9bc5 340 Gene3D G3DSA:3.90.180.10 5 329 3.6E-86 T 12-10-2018 TL08_05440 d6e00e4ca772b6699866b7b4f48d9bc5 340 SUPERFAMILY SSF50129 1 163 3.8E-43 T 12-10-2018 IPR011032 GroES-like superfamily TL08_05440 d6e00e4ca772b6699866b7b4f48d9bc5 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_05440 d6e00e4ca772b6699866b7b4f48d9bc5 340 Pfam PF00107 Zinc-binding dehydrogenase 175 286 1.5E-23 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_05440 d6e00e4ca772b6699866b7b4f48d9bc5 340 SUPERFAMILY SSF51735 146 306 1.2E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05440 d6e00e4ca772b6699866b7b4f48d9bc5 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 122 4.0E-21 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_05440 d6e00e4ca772b6699866b7b4f48d9bc5 340 Gene3D G3DSA:3.40.50.720 155 302 3.6E-86 T 12-10-2018 TL08_03630 0ea11335bcddd2173fa4970bf65d769f 228 SUPERFAMILY SSF161098 16 212 8.37E-38 T 12-10-2018 IPR035906 MetI-like superfamily TL08_03630 0ea11335bcddd2173fa4970bf65d769f 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 223 7.7E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_03630 0ea11335bcddd2173fa4970bf65d769f 228 Gene3D G3DSA:1.10.3720.10 8 222 1.6E-41 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23345 3bba3e472651a636d459334851a38d47 366 SUPERFAMILY SSF53697 68 353 1.69E-46 T 12-10-2018 TL08_23345 3bba3e472651a636d459334851a38d47 366 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 203 353 9.4E-8 T 12-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TL08_17090 99658c7c17d4fd864406972cf5bd4cea 117 Gene3D G3DSA:1.10.10.10 31 86 2.0E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17090 99658c7c17d4fd864406972cf5bd4cea 117 Pfam PF05331 Protein of unknown function (DUF742) 6 115 1.8E-35 T 12-10-2018 IPR007995 Protein of unknown function DUF742 TL08_17475 77fbb7dd33da91eccee7d8789438eef7 589 Pfam PF05954 Phage late control gene D protein (GPD) 64 346 9.0E-18 T 12-10-2018 TL08_17475 77fbb7dd33da91eccee7d8789438eef7 589 SUPERFAMILY SSF69279 36 189 2.55E-18 T 12-10-2018 TL08_17475 77fbb7dd33da91eccee7d8789438eef7 589 SUPERFAMILY SSF69255 381 457 6.02E-13 T 12-10-2018 TL08_17475 77fbb7dd33da91eccee7d8789438eef7 589 Gene3D G3DSA:2.30.110.50 64 345 3.1E-6 T 12-10-2018 TL08_17475 77fbb7dd33da91eccee7d8789438eef7 589 Gene3D G3DSA:2.40.50.230 375 461 7.4E-11 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily TL08_17475 77fbb7dd33da91eccee7d8789438eef7 589 Gene3D G3DSA:3.55.50.10 109 198 3.1E-6 T 12-10-2018 TL08_17475 77fbb7dd33da91eccee7d8789438eef7 589 Gene3D G3DSA:3.30.1920.30 242 305 3.1E-6 T 12-10-2018 TL08_21390 a2611419300ac6523387eec25cfbe56d 127 PRINTS PR00332 Histidine triad family signature 30 48 1.5E-16 T 12-10-2018 IPR001310 Histidine triad (HIT) protein TL08_21390 a2611419300ac6523387eec25cfbe56d 127 PRINTS PR00332 Histidine triad family signature 98 108 1.5E-16 T 12-10-2018 IPR001310 Histidine triad (HIT) protein TL08_21390 a2611419300ac6523387eec25cfbe56d 127 PRINTS PR00332 Histidine triad family signature 9 25 1.5E-16 T 12-10-2018 IPR001310 Histidine triad (HIT) protein TL08_21390 a2611419300ac6523387eec25cfbe56d 127 Gene3D G3DSA:3.30.428.10 1 114 9.9E-35 T 12-10-2018 IPR036265 HIT-like superfamily TL08_21390 a2611419300ac6523387eec25cfbe56d 127 Pfam PF01230 HIT domain 16 111 2.6E-23 T 12-10-2018 IPR001310 Histidine triad (HIT) protein TL08_21390 a2611419300ac6523387eec25cfbe56d 127 SUPERFAMILY SSF54197 5 115 3.56E-34 T 12-10-2018 IPR036265 HIT-like superfamily TL08_04750 04811503d015547ca2d9570685c2328b 297 PRINTS PR00412 Epoxide hydrolase signature 218 234 9.7E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_04750 04811503d015547ca2d9570685c2328b 297 PRINTS PR00412 Epoxide hydrolase signature 98 111 9.7E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_04750 04811503d015547ca2d9570685c2328b 297 PRINTS PR00412 Epoxide hydrolase signature 50 65 9.7E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_04750 04811503d015547ca2d9570685c2328b 297 PRINTS PR00412 Epoxide hydrolase signature 250 272 9.7E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_04750 04811503d015547ca2d9570685c2328b 297 SUPERFAMILY SSF53474 6 278 6.1E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_04750 04811503d015547ca2d9570685c2328b 297 Gene3D G3DSA:3.40.50.1820 18 274 1.0E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_04750 04811503d015547ca2d9570685c2328b 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_04750 04811503d015547ca2d9570685c2328b 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 220 234 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_04750 04811503d015547ca2d9570685c2328b 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_04750 04811503d015547ca2d9570685c2328b 297 Pfam PF12697 Alpha/beta hydrolase family 26 265 2.0E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_11785 8aaf435bff3a37ac01f9d81700adb04c 238 PIRSF PIRSF006648 1 238 9.1E-20 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_11785 8aaf435bff3a37ac01f9d81700adb04c 238 Pfam PF01061 ABC-2 type transporter 12 205 4.0E-17 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_10880 cdedbf78034a2c8a1e192801dffeedfe 325 Pfam PF01882 Protein of unknown function DUF58 64 148 2.1E-18 T 12-10-2018 IPR002881 Domain of unknown function DUF58 TL08_11825 66c2593ce36504941a43ebbad20f2ff9 436 Pfam PF00266 Aminotransferase class-V 31 411 6.0E-135 T 12-10-2018 IPR000192 Aminotransferase class V domain TL08_11825 66c2593ce36504941a43ebbad20f2ff9 436 Gene3D G3DSA:3.90.1150.10 13 414 3.2E-166 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_11825 66c2593ce36504941a43ebbad20f2ff9 436 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 232 251 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TL08_11825 66c2593ce36504941a43ebbad20f2ff9 436 Gene3D G3DSA:3.40.640.10 42 311 3.2E-166 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_11825 66c2593ce36504941a43ebbad20f2ff9 436 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 12 423 3.1E-171 T 12-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TL08_11825 66c2593ce36504941a43ebbad20f2ff9 436 SUPERFAMILY SSF53383 9 417 5.11E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_12645 0cc76368076d3dde11990361e3fe0deb 419 Pfam PF06722 Protein of unknown function (DUF1205) 199 291 2.4E-18 T 12-10-2018 IPR010610 Domain of unknown function DUF1205 TL08_12645 0cc76368076d3dde11990361e3fe0deb 419 SUPERFAMILY SSF53756 1 402 4.59E-72 T 12-10-2018 TL08_12645 0cc76368076d3dde11990361e3fe0deb 419 Gene3D G3DSA:3.40.50.2000 1 396 8.2E-100 T 12-10-2018 TL08_12645 0cc76368076d3dde11990361e3fe0deb 419 Gene3D G3DSA:3.40.50.2000 218 391 8.2E-100 T 12-10-2018 TL08_24125 2f230f488e6bdbe0c77155c48699e9be 374 Gene3D G3DSA:3.40.50.150 10 243 5.9E-53 T 12-10-2018 TL08_24125 2f230f488e6bdbe0c77155c48699e9be 374 SUPERFAMILY SSF53335 9 208 3.57E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_24125 2f230f488e6bdbe0c77155c48699e9be 374 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 16 209 5.9E-27 T 12-10-2018 TL08_25725 93c84b0c5e26e91fd65c43a285c45961 116 Pfam PF01638 HxlR-like helix-turn-helix 24 107 4.4E-22 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_25725 93c84b0c5e26e91fd65c43a285c45961 116 Gene3D G3DSA:1.10.10.10 7 115 3.7E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_25725 93c84b0c5e26e91fd65c43a285c45961 116 SUPERFAMILY SSF46785 13 108 3.44E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_04020 24194fb9f823096b2fa6fb49db9630a5 531 SUPERFAMILY SSF140453 11 97 3.4E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_04020 24194fb9f823096b2fa6fb49db9630a5 531 Pfam PF06259 Alpha/beta hydrolase 302 469 2.2E-28 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 TL08_04020 24194fb9f823096b2fa6fb49db9630a5 531 Gene3D G3DSA:1.10.287.1060 8 98 6.0E-9 T 12-10-2018 TL08_11210 a639982faa0eb6382d09f465698259d9 347 Pfam PF01636 Phosphotransferase enzyme family 31 288 2.7E-22 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_11210 a639982faa0eb6382d09f465698259d9 347 Gene3D G3DSA:3.90.1200.10 125 331 1.5E-21 T 12-10-2018 TL08_11210 a639982faa0eb6382d09f465698259d9 347 Gene3D G3DSA:3.30.200.20 17 110 8.3E-7 T 12-10-2018 TL08_11210 a639982faa0eb6382d09f465698259d9 347 SUPERFAMILY SSF56112 27 311 2.19E-27 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_12810 934568a3d7f31e45738aad53abffb748 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.1E-5 T 12-10-2018 TL08_12810 934568a3d7f31e45738aad53abffb748 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 1.1E-5 T 12-10-2018 TL08_12810 934568a3d7f31e45738aad53abffb748 413 Gene3D G3DSA:3.30.9.40 65 273 4.0E-131 T 12-10-2018 TL08_12810 934568a3d7f31e45738aad53abffb748 413 Gene3D G3DSA:3.50.50.60 4 325 4.0E-131 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_12810 934568a3d7f31e45738aad53abffb748 413 SUPERFAMILY SSF51905 2 358 1.59E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_04925 3e228ea0f660646176c71c1c76cfc77c 339 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 234 322 2.9E-11 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TL08_04925 3e228ea0f660646176c71c1c76cfc77c 339 Gene3D G3DSA:2.30.42.10 135 203 8.4E-11 T 12-10-2018 TL08_04925 3e228ea0f660646176c71c1c76cfc77c 339 Pfam PF13180 PDZ domain 133 199 1.1E-9 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TL08_04925 3e228ea0f660646176c71c1c76cfc77c 339 SUPERFAMILY SSF50156 132 234 2.93E-13 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TL08_04925 3e228ea0f660646176c71c1c76cfc77c 339 Gene3D G3DSA:3.30.230.10 204 331 7.1E-23 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_04925 3e228ea0f660646176c71c1c76cfc77c 339 SUPERFAMILY SSF54211 225 326 3.53E-20 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_15820 47559c191727258ef7b4cfb95aa69291 415 Gene3D G3DSA:1.20.1250.20 17 400 1.3E-26 T 12-10-2018 TL08_15820 47559c191727258ef7b4cfb95aa69291 415 SUPERFAMILY SSF103473 20 401 6.8E-27 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_15820 47559c191727258ef7b4cfb95aa69291 415 Pfam PF07690 Major Facilitator Superfamily 28 258 5.1E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_06530 26fdb1578ddc0665ecda5de8a1b05846 322 Gene3D G3DSA:1.20.58.340 266 322 1.3E-8 T 12-10-2018 TL08_06530 26fdb1578ddc0665ecda5de8a1b05846 322 Gene3D G3DSA:1.20.58.340 136 264 3.2E-37 T 12-10-2018 TL08_06530 26fdb1578ddc0665ecda5de8a1b05846 322 Pfam PF01544 CorA-like Mg2+ transporter protein 35 318 3.1E-57 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TL08_06530 26fdb1578ddc0665ecda5de8a1b05846 322 SUPERFAMILY SSF144083 258 319 3.66E-12 T 12-10-2018 TL08_06530 26fdb1578ddc0665ecda5de8a1b05846 322 SUPERFAMILY SSF143865 8 257 1.18E-58 T 12-10-2018 TL08_06530 26fdb1578ddc0665ecda5de8a1b05846 322 Gene3D G3DSA:3.30.460.20 5 133 8.3E-22 T 12-10-2018 TL08_16765 31cd4227aef1807c5f514100a552bf65 1116 Pfam PF13569 Domain of unknown function (DUF4132) 835 1027 1.9E-50 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_20955 c9cdf906e3c4dd2e32b20c5b95ab00fe 197 SUPERFAMILY SSF48498 92 193 6.88E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_20955 c9cdf906e3c4dd2e32b20c5b95ab00fe 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 1.1E-4 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_20955 c9cdf906e3c4dd2e32b20c5b95ab00fe 197 Gene3D G3DSA:1.10.357.10 10 196 3.6E-37 T 12-10-2018 TL08_20955 c9cdf906e3c4dd2e32b20c5b95ab00fe 197 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 101 192 2.2E-6 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal TL08_20955 c9cdf906e3c4dd2e32b20c5b95ab00fe 197 SUPERFAMILY SSF46689 9 77 7.18E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_26110 d5f203be14aa5fabd9ebb28e9bba1507 107 SUPERFAMILY SSF103481 5 105 1.96E-18 T 12-10-2018 TL08_26110 d5f203be14aa5fabd9ebb28e9bba1507 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 5.8E-24 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 TL08_26110 d5f203be14aa5fabd9ebb28e9bba1507 107 Gene3D G3DSA:1.10.3730.20 1 105 2.6E-30 T 12-10-2018 TL08_22775 b32446d6c9e60b536a478b6815842f46 679 Pfam PF00069 Protein kinase domain 15 261 1.3E-36 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TL08_22775 b32446d6c9e60b536a478b6815842f46 679 Gene3D G3DSA:3.30.200.20 7 93 3.7E-19 T 12-10-2018 TL08_22775 b32446d6c9e60b536a478b6815842f46 679 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TL08_22775 b32446d6c9e60b536a478b6815842f46 679 SUPERFAMILY SSF56112 11 264 3.1E-62 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_22775 b32446d6c9e60b536a478b6815842f46 679 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 133 145 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TL08_22775 b32446d6c9e60b536a478b6815842f46 679 Gene3D G3DSA:1.10.510.10 95 268 3.1E-42 T 12-10-2018 TL08_21125 f98729ba4b1749d1f5c4b33e01be2f52 391 Pfam PF07730 Histidine kinase 186 250 9.2E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_21125 f98729ba4b1749d1f5c4b33e01be2f52 391 SUPERFAMILY SSF55874 289 387 2.26E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_21125 f98729ba4b1749d1f5c4b33e01be2f52 391 Gene3D G3DSA:3.30.565.10 260 389 4.6E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_11680 8c2862316aa2ead006823ea3e8b4fe99 399 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 52 296 6.4E-88 T 12-10-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA TL08_11680 8c2862316aa2ead006823ea3e8b4fe99 399 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 2 305 3.1E-81 T 12-10-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA TL08_19370 b5b7e7981dec2ccecdd526567572379b 442 Gene3D G3DSA:3.40.190.10 77 369 1.4E-46 T 12-10-2018 TL08_19370 b5b7e7981dec2ccecdd526567572379b 442 Gene3D G3DSA:3.40.190.10 158 429 1.4E-46 T 12-10-2018 TL08_19370 b5b7e7981dec2ccecdd526567572379b 442 Pfam PF13416 Bacterial extracellular solute-binding protein 77 372 1.9E-21 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_19370 b5b7e7981dec2ccecdd526567572379b 442 SUPERFAMILY SSF53850 87 431 2.72E-41 T 12-10-2018 TL08_12065 de7c47b18d86586e408379b27e741773 280 SUPERFAMILY SSF56235 50 267 1.36E-54 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_12065 de7c47b18d86586e408379b27e741773 280 Gene3D G3DSA:3.60.20.10 54 280 2.8E-85 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_12065 de7c47b18d86586e408379b27e741773 280 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 274 3.0E-104 T 12-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 TL08_12065 de7c47b18d86586e408379b27e741773 280 Hamap MF_02113_B Proteasome subunit beta [prcB]. 10 280 47.858 T 12-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 TL08_12065 de7c47b18d86586e408379b27e741773 280 Pfam PF00227 Proteasome subunit 52 235 1.7E-32 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TL08_21775 9830e9c9bf2e4141e3afd88eb8ef0beb 356 SUPERFAMILY SSF47648 12 79 3.01E-18 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_21775 9830e9c9bf2e4141e3afd88eb8ef0beb 356 Gene3D G3DSA:1.20.970.10 10 75 1.8E-27 T 12-10-2018 TL08_21775 9830e9c9bf2e4141e3afd88eb8ef0beb 356 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 17 344 3.3E-109 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TL08_21775 9830e9c9bf2e4141e3afd88eb8ef0beb 356 Pfam PF00591 Glycosyl transferase family, a/b domain 83 336 6.1E-82 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_21775 9830e9c9bf2e4141e3afd88eb8ef0beb 356 Gene3D G3DSA:3.40.1030.10 82 354 2.8E-95 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_21775 9830e9c9bf2e4141e3afd88eb8ef0beb 356 Pfam PF02885 Glycosyl transferase family, helical bundle domain 15 74 9.2E-17 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_21775 9830e9c9bf2e4141e3afd88eb8ef0beb 356 SUPERFAMILY SSF52418 84 350 2.09E-80 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TL08_21775 9830e9c9bf2e4141e3afd88eb8ef0beb 356 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 14 346 33.788 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TL08_06455 b001cd65ab705dfb64963f56e0d467c4 330 SUPERFAMILY SSF141986 176 323 1.57E-11 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily TL08_06455 b001cd65ab705dfb64963f56e0d467c4 330 SUPERFAMILY SSF52317 1 143 1.83E-29 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_06455 b001cd65ab705dfb64963f56e0d467c4 330 Pfam PF02016 LD-carboxypeptidase 1 319 3.7E-53 T 12-10-2018 IPR003507 Peptidase family S66 TL08_06455 b001cd65ab705dfb64963f56e0d467c4 330 Gene3D G3DSA:3.50.30.60 146 329 7.7E-35 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily TL08_06455 b001cd65ab705dfb64963f56e0d467c4 330 Gene3D G3DSA:3.40.50.10740 1 143 1.3E-36 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal TL08_20520 9cd5566021ab8de5ef028934d96975ff 85 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 29 80 9.6E-10 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TL08_26510 f40351965be0b9bb3fe347de1cbc0314 291 Pfam PF13560 Helix-turn-helix domain 12 72 3.0E-13 T 12-10-2018 TL08_26510 f40351965be0b9bb3fe347de1cbc0314 291 SMART SM00530 16 71 1.2E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_26510 f40351965be0b9bb3fe347de1cbc0314 291 SUPERFAMILY SSF47413 13 70 2.18E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_26510 f40351965be0b9bb3fe347de1cbc0314 291 Gene3D G3DSA:1.10.260.40 4 79 6.9E-14 T 12-10-2018 TL08_13390 d4cc4410216249f0580d7cba08308d4f 396 SUPERFAMILY SSF103473 4 373 3.4E-50 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_13390 d4cc4410216249f0580d7cba08308d4f 396 Pfam PF07690 Major Facilitator Superfamily 9 324 1.3E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_13390 d4cc4410216249f0580d7cba08308d4f 396 Gene3D G3DSA:1.20.1250.20 3 199 2.0E-28 T 12-10-2018 TL08_13390 d4cc4410216249f0580d7cba08308d4f 396 Gene3D G3DSA:1.20.1250.20 200 380 3.8E-14 T 12-10-2018 TL08_25200 9baf10b412fad962165f97165afaefad 512 Pfam PF00860 Permease family 54 465 2.6E-25 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TL08_23990 ef233339dfc67c80618e0ea4dbb66861 88 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 81 4.6E-9 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TL08_21800 cf5a0b97f064b6a9b2de2a04774ec417 123 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 19 123 6.1E-34 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 TL08_21800 cf5a0b97f064b6a9b2de2a04774ec417 123 SUPERFAMILY SSF89360 19 112 4.71E-26 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TL08_21800 cf5a0b97f064b6a9b2de2a04774ec417 123 Gene3D G3DSA:2.60.300.12 19 123 3.0E-27 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TL08_21800 cf5a0b97f064b6a9b2de2a04774ec417 123 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 120 8.6E-18 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 TL08_21800 cf5a0b97f064b6a9b2de2a04774ec417 123 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 105 122 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 TL08_08255 5c7f2cf69f86f40efa62a8542dc69032 790 Gene3D G3DSA:3.60.15.10 528 773 1.9E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_08255 5c7f2cf69f86f40efa62a8542dc69032 790 Pfam PF13567 Domain of unknown function (DUF4131) 34 179 2.8E-6 T 12-10-2018 IPR025405 Domain of unknown function DUF4131 TL08_08255 5c7f2cf69f86f40efa62a8542dc69032 790 Pfam PF03772 Competence protein 232 498 8.1E-50 T 12-10-2018 IPR004477 ComEC/Rec2-related protein TL08_08255 5c7f2cf69f86f40efa62a8542dc69032 790 SUPERFAMILY SSF56281 526 773 6.77E-40 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_08255 5c7f2cf69f86f40efa62a8542dc69032 790 Pfam PF00753 Metallo-beta-lactamase superfamily 541 719 3.3E-10 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_08255 5c7f2cf69f86f40efa62a8542dc69032 790 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 254 421 4.9E-16 T 12-10-2018 IPR004477 ComEC/Rec2-related protein TL08_08255 5c7f2cf69f86f40efa62a8542dc69032 790 SMART SM00849 539 739 1.6E-5 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_06505 2940f34308f2bebedd631addd4946912 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 238 256 1.8E-19 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_06505 2940f34308f2bebedd631addd4946912 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 10 27 1.8E-19 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_06505 2940f34308f2bebedd631addd4946912 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 156 176 1.8E-19 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_06505 2940f34308f2bebedd631addd4946912 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 196 213 1.8E-19 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_06505 2940f34308f2bebedd631addd4946912 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 133 155 1.8E-19 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) TL08_06505 2940f34308f2bebedd631addd4946912 289 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 10 257 6.0E-55 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region TL08_06505 2940f34308f2bebedd631addd4946912 289 Gene3D G3DSA:2.120.10.30 1 289 3.8E-63 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_06505 2940f34308f2bebedd631addd4946912 289 SUPERFAMILY SSF63829 7 275 2.13E-40 T 12-10-2018 TL08_12905 02cc5dee09ffba735087b65972b85de7 493 Pfam PF00083 Sugar (and other) transporter 22 456 6.8E-40 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TL08_12905 02cc5dee09ffba735087b65972b85de7 493 SUPERFAMILY SSF103473 7 457 7.46E-65 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_25085 bf8872d6ef83db7c439ef487cb3d98bf 246 SUPERFAMILY SSF103473 33 167 1.57E-5 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_17480 0775a865090bc7f8009ff0e058c0347d 244 Gene3D G3DSA:3.10.350.10 181 226 1.6E-5 T 12-10-2018 IPR036779 LysM domain superfamily TL08_17480 0775a865090bc7f8009ff0e058c0347d 244 Pfam PF01476 LysM domain 184 229 4.0E-5 T 12-10-2018 IPR018392 LysM domain TL08_15235 0081458ffdd596d7570046f8324540cc 162 Gene3D G3DSA:1.10.10.10 2 161 1.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_15235 0081458ffdd596d7570046f8324540cc 162 Pfam PF01047 MarR family 53 111 6.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_15235 0081458ffdd596d7570046f8324540cc 162 SMART SM00347 46 146 1.3E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_15235 0081458ffdd596d7570046f8324540cc 162 SUPERFAMILY SSF46785 31 158 3.86E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_11645 e1675fdd4b29c91093b66385edaee24b 113 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 113 25.224 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 TL08_11645 e1675fdd4b29c91093b66385edaee24b 113 Gene3D G3DSA:2.20.28.270 1 81 2.9E-13 T 12-10-2018 IPR038638 RbpA superfamily TL08_11645 e1675fdd4b29c91093b66385edaee24b 113 Pfam PF13397 RNA polymerase-binding protein 5 108 6.7E-42 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 TL08_10445 636779d872300eaf6c18a33ca90ff981 493 Gene3D G3DSA:1.20.1530.20 70 469 2.5E-90 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TL08_10445 636779d872300eaf6c18a33ca90ff981 493 Pfam PF00999 Sodium/hydrogen exchanger family 77 463 1.1E-51 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TL08_06185 34f707f9a40dbd45767ae12958c46ab0 140 Gene3D G3DSA:1.10.10.10 2 120 5.5E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06185 34f707f9a40dbd45767ae12958c46ab0 140 Pfam PF12802 MarR family 13 71 8.5E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_06185 34f707f9a40dbd45767ae12958c46ab0 140 SUPERFAMILY SSF46785 9 122 9.85E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_06185 34f707f9a40dbd45767ae12958c46ab0 140 SMART SM00347 7 107 8.1E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_25845 e12814b223116b4fdfedd304f75299a0 305 SUPERFAMILY SSF103481 191 294 1.14E-8 T 12-10-2018 TL08_25845 e12814b223116b4fdfedd304f75299a0 305 SUPERFAMILY SSF103481 47 147 1.29E-9 T 12-10-2018 TL08_25845 e12814b223116b4fdfedd304f75299a0 305 Pfam PF00892 EamA-like transporter family 159 289 7.4E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_25845 e12814b223116b4fdfedd304f75299a0 305 Pfam PF00892 EamA-like transporter family 14 144 6.5E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_10370 8acd8d749bc6b7ec1f86cf4e491ed25c 254 Pfam PF02223 Thymidylate kinase 5 193 2.0E-6 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TL08_10370 8acd8d749bc6b7ec1f86cf4e491ed25c 254 Gene3D G3DSA:3.40.50.300 1 203 6.4E-17 T 12-10-2018 TL08_10370 8acd8d749bc6b7ec1f86cf4e491ed25c 254 SUPERFAMILY SSF52540 1 200 2.06E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14985 5eb34c32907e48943670db470546df2c 108 Gene3D G3DSA:1.10.10.690 3 106 9.0E-21 T 12-10-2018 IPR027405 YidB-like TL08_14985 5eb34c32907e48943670db470546df2c 108 SUPERFAMILY SSF140804 10 102 1.44E-20 T 12-10-2018 IPR027405 YidB-like TL08_13355 066d297bbcd369219d8e6b3a6a000922 411 Pfam PF07690 Major Facilitator Superfamily 21 246 3.2E-26 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_13355 066d297bbcd369219d8e6b3a6a000922 411 SUPERFAMILY SSF103473 9 387 6.67E-52 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_13355 066d297bbcd369219d8e6b3a6a000922 411 Gene3D G3DSA:1.20.1250.20 16 196 4.9E-25 T 12-10-2018 TL08_13355 066d297bbcd369219d8e6b3a6a000922 411 Gene3D G3DSA:1.20.1250.20 210 393 7.7E-13 T 12-10-2018 TL08_13245 e40af8e9fec73bdf392fcbe9e2a13db8 214 SUPERFAMILY SSF46785 19 79 7.55E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_13245 e40af8e9fec73bdf392fcbe9e2a13db8 214 Pfam PF12840 Helix-turn-helix domain 16 63 1.4E-6 T 12-10-2018 TL08_13245 e40af8e9fec73bdf392fcbe9e2a13db8 214 Gene3D G3DSA:1.10.10.10 13 84 4.1E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06560 85922247cf9b70aa1f09cd180e0c93ac 229 Pfam PF01551 Peptidase family M23 123 217 4.4E-30 T 12-10-2018 IPR016047 Peptidase M23 TL08_06560 85922247cf9b70aa1f09cd180e0c93ac 229 SUPERFAMILY SSF51261 70 221 1.83E-46 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_06560 85922247cf9b70aa1f09cd180e0c93ac 229 Gene3D G3DSA:2.70.70.10 76 224 1.9E-42 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_15325 85922247cf9b70aa1f09cd180e0c93ac 229 Pfam PF01551 Peptidase family M23 123 217 4.4E-30 T 12-10-2018 IPR016047 Peptidase M23 TL08_15325 85922247cf9b70aa1f09cd180e0c93ac 229 SUPERFAMILY SSF51261 70 221 1.83E-46 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_15325 85922247cf9b70aa1f09cd180e0c93ac 229 Gene3D G3DSA:2.70.70.10 76 224 1.9E-42 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_07925 5e910071075a58c1bff87b596e2dd718 209 Pfam PF01323 DSBA-like thioredoxin domain 13 167 2.0E-6 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 TL08_07925 5e910071075a58c1bff87b596e2dd718 209 SUPERFAMILY SSF52833 13 169 3.09E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_07925 5e910071075a58c1bff87b596e2dd718 209 Gene3D G3DSA:3.40.30.10 12 209 2.9E-72 T 12-10-2018 TL08_20165 7c8b3714ea1af269104f39f216d27e2c 450 Gene3D G3DSA:1.10.260.40 15 85 8.3E-7 T 12-10-2018 TL08_20165 7c8b3714ea1af269104f39f216d27e2c 450 SMART SM00530 33 88 4.7E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_20165 7c8b3714ea1af269104f39f216d27e2c 450 Pfam PF13560 Helix-turn-helix domain 34 86 1.1E-6 T 12-10-2018 TL08_20165 7c8b3714ea1af269104f39f216d27e2c 450 SUPERFAMILY SSF48452 203 322 2.53E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_20165 7c8b3714ea1af269104f39f216d27e2c 450 SUPERFAMILY SSF47413 35 85 2.55E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_20165 7c8b3714ea1af269104f39f216d27e2c 450 Gene3D G3DSA:1.25.40.10 195 350 8.3E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_12990 6592d9ce96c67863f6f30d942f62d319 257 Gene3D G3DSA:2.40.128.270 150 251 1.4E-5 T 12-10-2018 IPR038670 HslJ-like superfamily TL08_12990 6592d9ce96c67863f6f30d942f62d319 257 Pfam PF03724 META domain 144 249 4.8E-10 T 12-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ TL08_12990 6592d9ce96c67863f6f30d942f62d319 257 Pfam PF03724 META domain 31 130 2.2E-13 T 12-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ TL08_12990 6592d9ce96c67863f6f30d942f62d319 257 Gene3D G3DSA:2.40.128.270 29 137 1.2E-12 T 12-10-2018 IPR038670 HslJ-like superfamily TL08_02225 306a1149aea456fb84927812d7221e98 170 Pfam PF10698 Protein of unknown function (DUF2505) 13 162 2.7E-36 T 12-10-2018 IPR019639 Protein of unknown function DUF2505 TL08_12480 c957b05e605688c8be9a6cb59651365a 74 Pfam PF04149 Domain of unknown function (DUF397) 10 66 1.6E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_09395 cb45b750e5500a31998474c6c2f03b07 272 Pfam PF04012 PspA/IM30 family 3 240 2.4E-49 T 12-10-2018 IPR007157 PspA/IM30 TL08_22135 5c0727cbca71fcc941d0a55d6e7124ec 202 Gene3D G3DSA:3.40.30.10 12 202 2.3E-48 T 12-10-2018 TL08_22135 5c0727cbca71fcc941d0a55d6e7124ec 202 SUPERFAMILY SSF52833 13 171 7.38E-9 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 381 395 9.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 309 331 9.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 448 461 9.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 78 97 9.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 366 380 9.4E-30 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 39 490 8.0E-136 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 66 471 6.7E-115 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 Gene3D G3DSA:3.40.710.10 280 490 4.3E-58 T 12-10-2018 TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 Gene3D G3DSA:3.40.710.10 41 105 1.3E-7 T 12-10-2018 TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 SUPERFAMILY SSF56601 37 482 1.04E-99 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_13735 949adab10f0ea8712b18bfd1b2deea80 533 Gene3D G3DSA:3.50.80.20 106 201 4.4E-20 T 12-10-2018 TL08_01205 5033a8b3c42b5f61b83a55ad416af2f8 253 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 16 232 7.7E-26 T 12-10-2018 TL08_07830 74b759972fc9da6eec7520783eb8995e 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_07830 74b759972fc9da6eec7520783eb8995e 558 SUPERFAMILY SSF52540 8 241 3.91E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07830 74b759972fc9da6eec7520783eb8995e 558 Pfam PF00005 ABC transporter 338 471 2.3E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_07830 74b759972fc9da6eec7520783eb8995e 558 Gene3D G3DSA:3.40.50.300 2 282 1.8E-72 T 12-10-2018 TL08_07830 74b759972fc9da6eec7520783eb8995e 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 555 2.5E-265 T 12-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 TL08_07830 74b759972fc9da6eec7520783eb8995e 558 SUPERFAMILY SSF52540 307 507 3.75E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07830 74b759972fc9da6eec7520783eb8995e 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_07830 74b759972fc9da6eec7520783eb8995e 558 Pfam PF12848 ABC transporter 227 302 9.4E-14 T 12-10-2018 IPR032781 ABC-transporter extension domain TL08_07830 74b759972fc9da6eec7520783eb8995e 558 Gene3D G3DSA:3.40.50.300 284 557 4.9E-62 T 12-10-2018 TL08_07830 74b759972fc9da6eec7520783eb8995e 558 Pfam PF00005 ABC transporter 21 188 1.6E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_07830 74b759972fc9da6eec7520783eb8995e 558 SMART SM00382 30 233 7.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_07830 74b759972fc9da6eec7520783eb8995e 558 SMART SM00382 346 516 1.1E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_04065 1dcc324c9ca19560edde26b96cfc83bc 492 Gene3D G3DSA:3.40.50.150 260 468 6.3E-63 T 12-10-2018 TL08_04065 1dcc324c9ca19560edde26b96cfc83bc 492 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 2 461 1.4E-199 T 12-10-2018 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial TL08_04065 1dcc324c9ca19560edde26b96cfc83bc 492 Gene3D G3DSA:3.30.1610.20 1 231 4.5E-103 T 12-10-2018 IPR038546 Hen1, N-terminal domain superfamily TL08_04065 1dcc324c9ca19560edde26b96cfc83bc 492 Pfam PF13489 Methyltransferase domain 268 430 9.2E-9 T 12-10-2018 TL08_04065 1dcc324c9ca19560edde26b96cfc83bc 492 SUPERFAMILY SSF53335 268 431 3.0E-19 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_04065 1dcc324c9ca19560edde26b96cfc83bc 492 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 243 4.4E-112 T 12-10-2018 IPR024740 Hen1, N-terminal TL08_04785 f8265c5376e99e98f9eea6291f6bfaee 378 Pfam PF11350 Protein of unknown function (DUF3152) 166 375 3.9E-65 T 12-10-2018 IPR022603 Domain of unknown function DUF3152 TL08_04785 f8265c5376e99e98f9eea6291f6bfaee 378 SUPERFAMILY SSF55486 217 340 3.8E-13 T 12-10-2018 TL08_11965 aaaca3c7f7106ca06fcde3198dd1e15f 87 Gene3D G3DSA:1.10.287.1080 1 87 3.2E-22 T 12-10-2018 TL08_11965 aaaca3c7f7106ca06fcde3198dd1e15f 87 SUPERFAMILY SSF101386 2 87 1.16E-20 T 12-10-2018 TL08_11965 aaaca3c7f7106ca06fcde3198dd1e15f 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 17.628 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TL08_11965 aaaca3c7f7106ca06fcde3198dd1e15f 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 3.2E-21 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TL08_11965 aaaca3c7f7106ca06fcde3198dd1e15f 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 11 85 1.2E-6 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 TL08_21270 d357d68450127fbaf78b7249d95287d6 240 Gene3D G3DSA:2.40.260.10 102 236 5.0E-14 T 12-10-2018 IPR023365 Sortase domain superfamily TL08_21270 d357d68450127fbaf78b7249d95287d6 240 SUPERFAMILY SSF63817 93 235 1.57E-10 T 12-10-2018 IPR023365 Sortase domain superfamily TL08_21270 d357d68450127fbaf78b7249d95287d6 240 Pfam PF04203 Sortase family 133 233 1.8E-8 T 12-10-2018 IPR005754 Sortase family TL08_21025 c8a5272d8976661d8ecd7e91d7848d0b 202 Gene3D G3DSA:1.10.357.10 63 200 1.9E-34 T 12-10-2018 TL08_21025 c8a5272d8976661d8ecd7e91d7848d0b 202 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 191 7.6E-33 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TL08_21025 c8a5272d8976661d8ecd7e91d7848d0b 202 SUPERFAMILY SSF48498 84 196 5.26E-26 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_21025 c8a5272d8976661d8ecd7e91d7848d0b 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 69 2.5E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_21025 c8a5272d8976661d8ecd7e91d7848d0b 202 Gene3D G3DSA:1.10.10.60 16 61 4.7E-15 T 12-10-2018 TL08_21025 c8a5272d8976661d8ecd7e91d7848d0b 202 SUPERFAMILY SSF46689 17 73 2.19E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14845 03f35ddcd2c41786be4b8a2e5666f395 224 Pfam PF00293 NUDIX domain 7 132 1.7E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_14845 03f35ddcd2c41786be4b8a2e5666f395 224 Gene3D G3DSA:3.90.79.10 1 138 5.1E-39 T 12-10-2018 TL08_14845 03f35ddcd2c41786be4b8a2e5666f395 224 SUPERFAMILY SSF46785 147 216 5.58E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_14845 03f35ddcd2c41786be4b8a2e5666f395 224 Gene3D G3DSA:1.10.10.10 141 214 2.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_14845 03f35ddcd2c41786be4b8a2e5666f395 224 SUPERFAMILY SSF55811 4 140 9.07E-26 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_14845 03f35ddcd2c41786be4b8a2e5666f395 224 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_23950 1a3872b8d1dce0222a4463b5dd62a9c7 245 SMART SM00382 32 209 7.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_23950 1a3872b8d1dce0222a4463b5dd62a9c7 245 SUPERFAMILY SSF52540 6 224 6.05E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_23950 1a3872b8d1dce0222a4463b5dd62a9c7 245 Gene3D G3DSA:3.40.50.300 3 241 1.7E-66 T 12-10-2018 TL08_23950 1a3872b8d1dce0222a4463b5dd62a9c7 245 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_23950 1a3872b8d1dce0222a4463b5dd62a9c7 245 Pfam PF00005 ABC transporter 24 161 1.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_20205 63d61378795dbfd9a206e9e087b13fbc 437 PIRSF PIRSF006446 14 285 7.6E-79 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TL08_20205 63d61378795dbfd9a206e9e087b13fbc 437 PIRSF PIRSF006446 281 431 1.1E-27 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TL08_20205 63d61378795dbfd9a206e9e087b13fbc 437 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 21 273 3.9E-88 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TL08_20205 63d61378795dbfd9a206e9e087b13fbc 437 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 293 415 2.3E-24 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 TL08_16030 fbba7d47b5f0b2db56edb7d8956f06ca 286 Pfam PF05977 Transmembrane secretion effector 55 247 3.5E-13 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_16030 fbba7d47b5f0b2db56edb7d8956f06ca 286 SUPERFAMILY SSF103473 45 252 1.14E-13 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_16030 fbba7d47b5f0b2db56edb7d8956f06ca 286 Gene3D G3DSA:1.20.1250.20 36 198 7.4E-11 T 12-10-2018 TL08_10705 86ff6088eb9cf2be4106e038b6debd74 381 SUPERFAMILY SSF51905 4 377 9.06E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_10705 86ff6088eb9cf2be4106e038b6debd74 381 Pfam PF01266 FAD dependent oxidoreductase 5 359 3.3E-52 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_10705 86ff6088eb9cf2be4106e038b6debd74 381 Gene3D G3DSA:3.30.9.10 60 320 1.5E-119 T 12-10-2018 TL08_10705 86ff6088eb9cf2be4106e038b6debd74 381 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 TL08_10705 86ff6088eb9cf2be4106e038b6debd74 381 Gene3D G3DSA:3.50.50.60 5 363 1.5E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_10705 86ff6088eb9cf2be4106e038b6debd74 381 SUPERFAMILY SSF54373 215 320 1.65E-16 T 12-10-2018 TL08_21815 3d973112d645869833a68c11e495eac3 327 Pfam PF00248 Aldo/keto reductase family 15 312 2.2E-75 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_21815 3d973112d645869833a68c11e495eac3 327 SUPERFAMILY SSF51430 1 313 4.98E-96 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_21815 3d973112d645869833a68c11e495eac3 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 109 119 1.4E-5 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TL08_21815 3d973112d645869833a68c11e495eac3 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 256 268 1.4E-5 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TL08_21815 3d973112d645869833a68c11e495eac3 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 203 209 1.4E-5 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TL08_21815 3d973112d645869833a68c11e495eac3 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 269 282 1.4E-5 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TL08_21815 3d973112d645869833a68c11e495eac3 327 Gene3D G3DSA:3.20.20.100 1 322 2.3E-112 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_18010 112998775759437db90739973f265ce7 139 Pfam PF08044 Domain of unknown function (DUF1707) 1 42 1.9E-12 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_18010 112998775759437db90739973f265ce7 139 Pfam PF05154 TM2 domain 72 122 1.3E-10 T 12-10-2018 IPR007829 TM2 domain TL08_01595 f00a0db70d5b10f4c201a8fbaab5aad1 81 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 9 67 1.1E-18 T 12-10-2018 IPR018691 Protein of unknown function DUF2188 TL08_11045 60d90dd6342f88da3eb21ee1f9efe4f9 212 Gene3D G3DSA:3.30.565.10 17 140 2.1E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_20805 601ea6111f4d709f35485791b7df6173 214 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 35 156 8.4E-15 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TL08_20805 601ea6111f4d709f35485791b7df6173 214 Gene3D G3DSA:3.30.530.20 8 191 4.0E-39 T 12-10-2018 IPR023393 START-like domain superfamily TL08_20805 601ea6111f4d709f35485791b7df6173 214 SUPERFAMILY SSF55961 14 162 4.44E-31 T 12-10-2018 TL08_20840 7672e3809526738d10f753bf37267e30 671 SUPERFAMILY SSF48371 370 536 1.01E-9 T 12-10-2018 IPR016024 Armadillo-type fold TL08_20840 7672e3809526738d10f753bf37267e30 671 Gene3D G3DSA:1.25.10.10 356 618 1.1E-8 T 12-10-2018 IPR011989 Armadillo-like helical TL08_14250 6e80f781eaef065a5f932a57d4313b32 257 SUPERFAMILY SSF52218 1 233 1.15E-66 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_14250 6e80f781eaef065a5f932a57d4313b32 257 Gene3D G3DSA:3.40.50.360 1 254 4.4E-88 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_14250 6e80f781eaef065a5f932a57d4313b32 257 Pfam PF02525 Flavodoxin-like fold 1 212 8.7E-57 T 12-10-2018 IPR003680 Flavodoxin-like fold TL08_25675 6089cc2621d05aa18c118bc7eb37547d 219 Pfam PF02585 GlcNAc-PI de-N-acetylase 14 126 3.0E-14 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TL08_25675 6089cc2621d05aa18c118bc7eb37547d 219 Gene3D G3DSA:3.40.50.10320 10 218 1.5E-26 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_25675 6089cc2621d05aa18c118bc7eb37547d 219 SUPERFAMILY SSF102588 12 211 3.4E-32 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_16655 b8ce861e0491ad5de01b4cd2d6922d3e 291 SUPERFAMILY SSF56112 24 235 6.12E-29 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_16655 b8ce861e0491ad5de01b4cd2d6922d3e 291 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 33 262 6.7E-23 T 12-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 TL08_16655 b8ce861e0491ad5de01b4cd2d6922d3e 291 Gene3D G3DSA:3.90.1200.10 121 242 3.7E-11 T 12-10-2018 TL08_08130 c0d89e2d7b5939b20a3b33d3033dc9d9 284 Pfam PF01061 ABC-2 type transporter 38 247 7.9E-20 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_08130 c0d89e2d7b5939b20a3b33d3033dc9d9 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 53 74 3.9E-17 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_08130 c0d89e2d7b5939b20a3b33d3033dc9d9 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 226 245 3.9E-17 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_08130 c0d89e2d7b5939b20a3b33d3033dc9d9 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 170 194 3.9E-17 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_08130 c0d89e2d7b5939b20a3b33d3033dc9d9 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 133 158 3.9E-17 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_08130 c0d89e2d7b5939b20a3b33d3033dc9d9 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 3.9E-17 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_08130 c0d89e2d7b5939b20a3b33d3033dc9d9 284 PIRSF PIRSF006648 3 282 9.4E-26 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_25585 e9f0124653b190e95e60678eb8ee44ee 225 Gene3D G3DSA:1.10.340.30 28 209 2.3E-71 T 12-10-2018 TL08_25585 e9f0124653b190e95e60678eb8ee44ee 225 SUPERFAMILY SSF48150 29 206 1.0E-65 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TL08_25585 e9f0124653b190e95e60678eb8ee44ee 225 Pfam PF03352 Methyladenine glycosylase 33 204 5.9E-66 T 12-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 TL08_24175 a70265011a6c5f82979afd431f598ac3 357 Gene3D G3DSA:3.40.50.1820 32 356 1.5E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_24175 a70265011a6c5f82979afd431f598ac3 357 Pfam PF12697 Alpha/beta hydrolase family 83 346 3.5E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_24175 a70265011a6c5f82979afd431f598ac3 357 SUPERFAMILY SSF53474 55 357 1.06E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_26020 9484fb71bfc7a0c86a68a24ac9d71033 126 SUPERFAMILY SSF55718 66 124 8.24E-5 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TL08_26020 9484fb71bfc7a0c86a68a24ac9d71033 126 Gene3D G3DSA:3.30.1050.40 1 126 5.6E-52 T 12-10-2018 TL08_05655 7fe121edeb23ea2e68ee471ad85f08bd 228 Pfam PF02698 DUF218 domain 40 156 2.3E-17 T 12-10-2018 IPR003848 Domain of unknown function DUF218 TL08_05655 7fe121edeb23ea2e68ee471ad85f08bd 228 Gene3D G3DSA:3.40.50.620 31 165 1.5E-14 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_09530 f204486f659ee593fc9e502a2de71427 459 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TL08_09530 f204486f659ee593fc9e502a2de71427 459 SUPERFAMILY SSF55307 201 315 8.93E-43 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 Gene3D G3DSA:3.30.1330.20 218 325 6.2E-39 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.2E-35 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TL08_09530 f204486f659ee593fc9e502a2de71427 459 Gene3D G3DSA:3.40.50.1440 1 217 3.4E-80 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 PRINTS PR00423 Cell division protein FtsZ signature 95 115 9.7E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 PRINTS PR00423 Cell division protein FtsZ signature 186 208 9.7E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 PRINTS PR00423 Cell division protein FtsZ signature 123 144 9.7E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 PRINTS PR00423 Cell division protein FtsZ signature 209 230 9.7E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 SMART SM00864 10 202 1.4E-108 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 SUPERFAMILY SSF52490 9 205 1.02E-65 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 SMART SM00865 204 321 4.8E-56 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 6.7E-38 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TL08_09530 f204486f659ee593fc9e502a2de71427 459 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 314 8.8E-127 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TL08_09530 f204486f659ee593fc9e502a2de71427 459 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TL08_09530 f204486f659ee593fc9e502a2de71427 459 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 390 38.282 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TL08_04415 1868179321d64e4377e4d9d268ba25c4 334 SUPERFAMILY SSF55811 198 318 3.79E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_04415 1868179321d64e4377e4d9d268ba25c4 334 PRINTS PR00502 NUDIX hydrolase family signature 239 254 3.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_04415 1868179321d64e4377e4d9d268ba25c4 334 PRINTS PR00502 NUDIX hydrolase family signature 225 239 3.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_04415 1868179321d64e4377e4d9d268ba25c4 334 Gene3D G3DSA:3.90.79.10 197 322 5.4E-27 T 12-10-2018 TL08_04415 1868179321d64e4377e4d9d268ba25c4 334 Pfam PF00293 NUDIX domain 199 306 3.9E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_04415 1868179321d64e4377e4d9d268ba25c4 334 SUPERFAMILY SSF55961 43 187 2.84E-9 T 12-10-2018 TL08_04415 1868179321d64e4377e4d9d268ba25c4 334 Gene3D G3DSA:3.30.530.20 41 196 1.5E-5 T 12-10-2018 IPR023393 START-like domain superfamily TL08_26875 bcfe52702b9fda029ec475082bf60a6a 200 SUPERFAMILY SSF160631 31 169 4.05E-7 T 12-10-2018 TL08_18860 a6ed04bfb4e2d0757ffd7cefe31470eb 150 SUPERFAMILY SSF82607 22 105 2.22E-5 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_06595 010c4f7677880f65d03e73cd1898d0d6 104 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 99 1.9E-10 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 TL08_06595 010c4f7677880f65d03e73cd1898d0d6 104 Gene3D G3DSA:1.10.287.1060 2 101 2.4E-17 T 12-10-2018 TL08_06595 010c4f7677880f65d03e73cd1898d0d6 104 SUPERFAMILY SSF140453 5 101 1.2E-9 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_20960 3c1bf51eee0da3731d9738b128109426 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.4E-17 T 12-10-2018 TL08_20960 3c1bf51eee0da3731d9738b128109426 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 288 1.4E-17 T 12-10-2018 TL08_20960 3c1bf51eee0da3731d9738b128109426 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.4E-17 T 12-10-2018 TL08_20960 3c1bf51eee0da3731d9738b128109426 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 304 1.4E-17 T 12-10-2018 TL08_20960 3c1bf51eee0da3731d9738b128109426 394 SUPERFAMILY SSF51905 7 371 2.59E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_20960 3c1bf51eee0da3731d9738b128109426 394 Gene3D G3DSA:3.30.9.30 39 347 2.9E-90 T 12-10-2018 TL08_20960 3c1bf51eee0da3731d9738b128109426 394 Pfam PF01494 FAD binding domain 8 341 2.2E-25 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_20960 3c1bf51eee0da3731d9738b128109426 394 Gene3D G3DSA:3.50.50.60 8 343 2.9E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_26360 8900304dbde3843f705fe646fe3cbd6d 127 Pfam PF13602 Zinc-binding dehydrogenase 18 124 3.0E-9 T 12-10-2018 TL08_26360 8900304dbde3843f705fe646fe3cbd6d 127 Gene3D G3DSA:3.90.180.10 76 124 3.9E-13 T 12-10-2018 TL08_26360 8900304dbde3843f705fe646fe3cbd6d 127 Gene3D G3DSA:3.40.50.720 6 75 3.9E-13 T 12-10-2018 TL08_06540 8d45385f818a32af91639afa48284049 208 Hamap MF_01405 dITP/XTP pyrophosphatase. 6 205 48.439 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 TL08_06540 8d45385f818a32af91639afa48284049 208 Pfam PF01725 Ham1 family 8 200 2.1E-56 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TL08_06540 8d45385f818a32af91639afa48284049 208 Gene3D G3DSA:3.90.950.10 3 207 2.4E-72 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TL08_06540 8d45385f818a32af91639afa48284049 208 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 8 200 3.7E-47 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TL08_06540 8d45385f818a32af91639afa48284049 208 SUPERFAMILY SSF52972 5 204 1.02E-62 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TL08_06010 aecd5da13b054c7b8db25a462bd9da37 193 Gene3D G3DSA:1.10.357.10 10 187 3.0E-31 T 12-10-2018 TL08_06010 aecd5da13b054c7b8db25a462bd9da37 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 6.2E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06010 aecd5da13b054c7b8db25a462bd9da37 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 6.2E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06010 aecd5da13b054c7b8db25a462bd9da37 193 SUPERFAMILY SSF46689 2 80 1.51E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06010 aecd5da13b054c7b8db25a462bd9da37 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 8.6E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_07900 467f831984e9845e79d988c71109158e 224 Pfam PF14279 HNH endonuclease 141 187 3.4E-12 T 12-10-2018 IPR029471 HNH endonuclease 5 TL08_07900 467f831984e9845e79d988c71109158e 224 SMART SM00507 128 177 2.2E-14 T 12-10-2018 IPR003615 HNH nuclease TL08_07900 467f831984e9845e79d988c71109158e 224 Gene3D G3DSA:3.30.40.60 125 198 1.0E-18 T 12-10-2018 TL08_13560 fbc90a004ce65e2afe87f070742789e6 280 SUPERFAMILY SSF63380 14 140 5.96E-13 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TL08_13560 fbc90a004ce65e2afe87f070742789e6 280 Pfam PF04954 Siderophore-interacting protein 155 272 4.3E-40 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain TL08_13560 fbc90a004ce65e2afe87f070742789e6 280 Pfam PF08021 Siderophore-interacting FAD-binding domain 25 141 3.5E-41 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting TL08_13560 fbc90a004ce65e2afe87f070742789e6 280 Gene3D G3DSA:3.40.50.80 151 280 4.9E-44 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TL08_13560 fbc90a004ce65e2afe87f070742789e6 280 Gene3D G3DSA:2.40.30.10 5 141 9.4E-43 T 12-10-2018 TL08_02780 a9e15a79543d8541a49b8d83f010f967 522 Pfam PF08386 TAP-like protein 417 516 6.5E-22 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal TL08_02780 a9e15a79543d8541a49b8d83f010f967 522 SUPERFAMILY SSF53474 86 489 3.33E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_02780 a9e15a79543d8541a49b8d83f010f967 522 Pfam PF00561 alpha/beta hydrolase fold 84 241 2.1E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_08730 83d9cfc5d1e83e696b5248097d390209 197 Pfam PF13599 Pentapeptide repeats (9 copies) 64 130 1.8E-10 T 12-10-2018 IPR001646 Pentapeptide repeat TL08_08730 83d9cfc5d1e83e696b5248097d390209 197 SUPERFAMILY SSF141571 23 193 7.65E-37 T 12-10-2018 TL08_08730 83d9cfc5d1e83e696b5248097d390209 197 Gene3D G3DSA:2.160.20.100 22 197 2.7E-44 T 12-10-2018 TL08_07780 067ad0f8a0f2a79db6d2b715c5a4711a 105 SUPERFAMILY SSF55729 7 91 1.6E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_07780 067ad0f8a0f2a79db6d2b715c5a4711a 105 Gene3D G3DSA:3.40.630.30 3 95 5.3E-22 T 12-10-2018 TL08_07780 067ad0f8a0f2a79db6d2b715c5a4711a 105 Pfam PF14542 GCN5-related N-acetyl-transferase 12 89 8.0E-21 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase TL08_08170 a31e7d5659db7f5b59a6552df9c1c4c2 784 Gene3D G3DSA:1.10.3720.10 508 768 8.4E-14 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08170 a31e7d5659db7f5b59a6552df9c1c4c2 784 Gene3D G3DSA:1.10.3720.10 320 482 3.0E-20 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08170 a31e7d5659db7f5b59a6552df9c1c4c2 784 Gene3D G3DSA:1.10.3720.10 49 176 4.2E-7 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08170 a31e7d5659db7f5b59a6552df9c1c4c2 784 SUPERFAMILY SSF161098 51 171 1.96E-7 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08170 a31e7d5659db7f5b59a6552df9c1c4c2 784 SUPERFAMILY SSF161098 350 473 2.62E-17 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08170 a31e7d5659db7f5b59a6552df9c1c4c2 784 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 352 474 8.2E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_08170 a31e7d5659db7f5b59a6552df9c1c4c2 784 SUPERFAMILY SSF161098 509 776 7.96E-20 T 12-10-2018 IPR035906 MetI-like superfamily TL08_12355 1dba4e080805c777d2cc6ddc445cb9fa 370 Pfam PF01032 FecCD transport family 56 360 3.2E-79 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_12355 1dba4e080805c777d2cc6ddc445cb9fa 370 Gene3D G3DSA:1.10.3470.10 43 366 3.6E-89 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_12355 1dba4e080805c777d2cc6ddc445cb9fa 370 SUPERFAMILY SSF81345 43 360 6.15E-71 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_04040 39553da6f5496eb9373410a2e4f7eff5 315 Pfam PF01636 Phosphotransferase enzyme family 52 244 2.0E-8 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_04040 39553da6f5496eb9373410a2e4f7eff5 315 SUPERFAMILY SSF56112 31 244 1.2E-18 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_00540 56f8b28aaa5bfe7666f4576bc62e88dc 394 Gene3D G3DSA:2.60.120.10 269 364 4.9E-6 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_00540 56f8b28aaa5bfe7666f4576bc62e88dc 394 Gene3D G3DSA:2.60.120.10 81 174 4.1E-8 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_00540 56f8b28aaa5bfe7666f4576bc62e88dc 394 SUPERFAMILY SSF51182 6 386 8.23E-92 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_00540 56f8b28aaa5bfe7666f4576bc62e88dc 394 Pfam PF04209 homogentisate 1,2-dioxygenase 20 384 6.4E-18 T 12-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 TL08_25215 42be1fc2cb50a2ed0d88d65f92a5535d 456 Pfam PF11228 Protein of unknown function (DUF3027) 52 242 1.9E-80 T 12-10-2018 IPR021391 Protein of unknown function DUF3027 TL08_20665 0098f6de3150baa8f66957888655951f 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 292 3.8E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_20665 0098f6de3150baa8f66957888655951f 301 SUPERFAMILY SSF161098 25 301 6.8E-73 T 12-10-2018 IPR035906 MetI-like superfamily TL08_20665 0098f6de3150baa8f66957888655951f 301 Gene3D G3DSA:1.10.3720.10 19 292 2.1E-65 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13500 9e546e2a4a48bbe4bcca30959d64ff3f 183 SUPERFAMILY SSF46785 13 144 2.79E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_13500 9e546e2a4a48bbe4bcca30959d64ff3f 183 Pfam PF13463 Winged helix DNA-binding domain 52 106 7.2E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13500 9e546e2a4a48bbe4bcca30959d64ff3f 183 SMART SM00347 32 137 0.0063 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13500 9e546e2a4a48bbe4bcca30959d64ff3f 183 Gene3D G3DSA:1.10.10.10 6 159 1.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06390 fab3a99e65f5c4429b8b39925af1cc38 396 Pfam PF13449 Esterase-like activity of phytase 51 382 4.1E-65 T 12-10-2018 IPR027372 Phytase-like domain TL08_11085 25fe266728c4ac36b5b48b24cdbdbe48 198 SUPERFAMILY SSF81301 16 152 1.14E-27 T 12-10-2018 TL08_11085 25fe266728c4ac36b5b48b24cdbdbe48 198 Gene3D G3DSA:3.30.460.40 8 147 2.7E-11 T 12-10-2018 TL08_11085 25fe266728c4ac36b5b48b24cdbdbe48 198 Pfam PF14907 Uncharacterised nucleotidyltransferase 11 146 6.8E-8 T 12-10-2018 IPR039498 Uncharacterised nucleotidyltransferase TL08_00500 426f69a9cfd5528a8c15153d7f7ae155 186 SUPERFAMILY SSF47240 15 157 1.53E-42 T 12-10-2018 IPR009078 Ferritin-like superfamily TL08_00500 426f69a9cfd5528a8c15153d7f7ae155 186 Gene3D G3DSA:1.20.1260.10 7 186 1.3E-50 T 12-10-2018 IPR012347 Ferritin-like TL08_00500 426f69a9cfd5528a8c15153d7f7ae155 186 Pfam PF00210 Ferritin-like domain 17 152 9.8E-33 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TL08_11335 9dd64de12b517c2d0e02512076354da1 435 SUPERFAMILY SSF51905 5 270 1.42E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_11335 9dd64de12b517c2d0e02512076354da1 435 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 341 5.1E-106 T 12-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase TL08_11335 9dd64de12b517c2d0e02512076354da1 435 SUPERFAMILY SSF51905 191 367 1.01E-6 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_11335 9dd64de12b517c2d0e02512076354da1 435 Gene3D G3DSA:3.50.50.60 1 424 2.2E-114 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_04715 154f7784d98d8c9e3293c2220b37fd2d 360 SUPERFAMILY SSF143865 19 292 1.27E-65 T 12-10-2018 TL08_04715 154f7784d98d8c9e3293c2220b37fd2d 360 Gene3D G3DSA:1.20.58.340 283 360 1.1E-21 T 12-10-2018 TL08_04715 154f7784d98d8c9e3293c2220b37fd2d 360 Pfam PF01544 CorA-like Mg2+ transporter protein 62 356 5.4E-59 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TL08_04715 154f7784d98d8c9e3293c2220b37fd2d 360 SUPERFAMILY SSF144083 295 357 5.1E-18 T 12-10-2018 TL08_04715 154f7784d98d8c9e3293c2220b37fd2d 360 Gene3D G3DSA:1.20.58.340 172 282 5.4E-30 T 12-10-2018 TL08_04715 154f7784d98d8c9e3293c2220b37fd2d 360 Gene3D G3DSA:3.30.460.20 12 171 3.0E-28 T 12-10-2018 TL08_09270 0e535b9f0b60034c27d480bb22188f4b 455 Gene3D G3DSA:1.20.1250.20 223 445 4.0E-70 T 12-10-2018 TL08_09270 0e535b9f0b60034c27d480bb22188f4b 455 Pfam PF07690 Major Facilitator Superfamily 51 365 1.5E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_09270 0e535b9f0b60034c27d480bb22188f4b 455 Gene3D G3DSA:1.20.1250.20 3 222 2.3E-71 T 12-10-2018 TL08_09270 0e535b9f0b60034c27d480bb22188f4b 455 SUPERFAMILY SSF103473 16 439 1.44E-38 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_08325 09091747cabd2356d5091df39967d087 273 Pfam PF07070 SpoOM protein 2 222 4.9E-56 T 12-10-2018 IPR009776 Sporulation stage 0, protein M TL08_03700 6274724f3173a4d571c0aab9c60097fa 503 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 20 476 2.6E-170 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TL08_03700 6274724f3173a4d571c0aab9c60097fa 503 SUPERFAMILY SSF51161 272 472 5.85E-37 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TL08_03700 6274724f3173a4d571c0aab9c60097fa 503 SUPERFAMILY SSF53448 20 276 7.66E-60 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_03700 6274724f3173a4d571c0aab9c60097fa 503 Pfam PF12804 MobA-like NTP transferase domain 22 166 6.6E-19 T 12-10-2018 IPR025877 MobA-like NTP transferase TL08_03700 6274724f3173a4d571c0aab9c60097fa 503 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 18 475 39.809 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TL08_03700 6274724f3173a4d571c0aab9c60097fa 503 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 342 374 0.0013 T 12-10-2018 IPR001451 Hexapeptide repeat TL08_03700 6274724f3173a4d571c0aab9c60097fa 503 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 418 451 4.8E-4 T 12-10-2018 IPR001451 Hexapeptide repeat TL08_03700 6274724f3173a4d571c0aab9c60097fa 503 Gene3D G3DSA:2.160.10.10 276 463 4.4E-48 T 12-10-2018 TL08_03700 6274724f3173a4d571c0aab9c60097fa 503 Gene3D G3DSA:3.90.550.10 15 275 4.2E-71 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_07860 19d7a1e7c9c0295ea72f2a367041087d 133 Pfam PF01152 Bacterial-like globin 12 128 2.6E-35 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 TL08_07860 19d7a1e7c9c0295ea72f2a367041087d 133 Gene3D G3DSA:1.10.490.10 9 133 1.2E-48 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TL08_07860 19d7a1e7c9c0295ea72f2a367041087d 133 SUPERFAMILY SSF46458 12 131 7.2E-37 T 12-10-2018 IPR009050 Globin-like superfamily TL08_08555 4855108c63580727b8d16d1dc0d00907 307 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 303 26.499 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TL08_08555 4855108c63580727b8d16d1dc0d00907 307 Gene3D G3DSA:3.40.50.300 12 291 6.1E-87 T 12-10-2018 TL08_08555 4855108c63580727b8d16d1dc0d00907 307 Pfam PF01715 IPP transferase 41 287 5.4E-72 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TL08_08555 4855108c63580727b8d16d1dc0d00907 307 Gene3D G3DSA:1.10.20.140 115 185 6.1E-87 T 12-10-2018 TL08_08555 4855108c63580727b8d16d1dc0d00907 307 SUPERFAMILY SSF52540 8 149 1.57E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_08555 4855108c63580727b8d16d1dc0d00907 307 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 9 294 1.8E-70 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TL08_02920 fdab2ae8f4002a1f2aadb58f4a9c0d8d 82 Pfam PF04149 Domain of unknown function (DUF397) 21 76 6.4E-14 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_00920 1786838dab7eebd6cbe47f248a770b62 283 Pfam PF00005 ABC transporter 28 179 4.7E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_00920 1786838dab7eebd6cbe47f248a770b62 283 SMART SM00382 36 228 1.1E-21 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_00920 1786838dab7eebd6cbe47f248a770b62 283 Gene3D G3DSA:3.40.50.300 4 269 4.5E-85 T 12-10-2018 TL08_00920 1786838dab7eebd6cbe47f248a770b62 283 SUPERFAMILY SSF52540 6 250 6.41E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_00920 1786838dab7eebd6cbe47f248a770b62 283 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_00920 1786838dab7eebd6cbe47f248a770b62 283 PIRSF PIRSF037116 1 257 1.5E-58 T 12-10-2018 IPR012700 Phosphonate C-P lyase system, PhnK TL08_15460 9292c6cbbc872e58889a19834e9a2997 393 SMART SM00530 8 63 6.6E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_15460 9292c6cbbc872e58889a19834e9a2997 393 Gene3D G3DSA:1.25.40.10 98 377 8.3E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_15460 9292c6cbbc872e58889a19834e9a2997 393 Pfam PF13560 Helix-turn-helix domain 4 62 1.9E-9 T 12-10-2018 TL08_15460 9292c6cbbc872e58889a19834e9a2997 393 Gene3D G3DSA:1.10.260.40 2 67 5.2E-13 T 12-10-2018 TL08_15460 9292c6cbbc872e58889a19834e9a2997 393 SUPERFAMILY SSF47413 4 66 4.79E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_10460 cbf33194e8ed88286e87a0f91f486fca 142 SUPERFAMILY SSF51182 18 135 2.82E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_10460 cbf33194e8ed88286e87a0f91f486fca 142 PIRSF PIRSF016602 1 139 8.0E-53 T 12-10-2018 IPR016672 Polyketide biosynthesis protein CurC, predicted TL08_10460 cbf33194e8ed88286e87a0f91f486fca 142 Pfam PF07883 Cupin domain 42 108 3.6E-17 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TL08_10460 cbf33194e8ed88286e87a0f91f486fca 142 Gene3D G3DSA:2.60.120.10 13 120 4.8E-17 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_09935 0d00697361d63c8f6898e6eb2332d01a 427 SUPERFAMILY SSF48208 60 422 4.25E-75 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_09935 0d00697361d63c8f6898e6eb2332d01a 427 Gene3D G3DSA:1.50.10.10 65 421 1.5E-114 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_09935 0d00697361d63c8f6898e6eb2332d01a 427 Pfam PF01270 Glycosyl hydrolases family 8 59 419 1.0E-21 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TL08_09935 0d00697361d63c8f6898e6eb2332d01a 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 167 185 1.0E-22 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TL08_09935 0d00697361d63c8f6898e6eb2332d01a 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 278 289 1.0E-22 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TL08_09935 0d00697361d63c8f6898e6eb2332d01a 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 105 118 1.0E-22 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TL08_09935 0d00697361d63c8f6898e6eb2332d01a 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 407 421 1.0E-22 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TL08_09935 0d00697361d63c8f6898e6eb2332d01a 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 235 252 1.0E-22 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TL08_09935 0d00697361d63c8f6898e6eb2332d01a 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 308 317 1.0E-22 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TL08_14500 3b1f85e2e3b1fc1179e202c340da8efe 201 Gene3D G3DSA:3.40.50.720 2 200 2.5E-33 T 12-10-2018 TL08_14500 3b1f85e2e3b1fc1179e202c340da8efe 201 SUPERFAMILY SSF51735 2 197 6.45E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14500 3b1f85e2e3b1fc1179e202c340da8efe 201 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 33 167 2.9E-11 T 12-10-2018 TL08_10260 d6abc49a989348cf41ac5d92c93785fa 692 Pfam PF01757 Acyltransferase family 35 365 2.7E-21 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_14805 922700e1b8be2550bb4e227f34dbf0e6 305 Gene3D G3DSA:1.10.3720.10 91 305 1.0E-21 T 12-10-2018 IPR035906 MetI-like superfamily TL08_14805 922700e1b8be2550bb4e227f34dbf0e6 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 304 3.2E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_14805 922700e1b8be2550bb4e227f34dbf0e6 305 SUPERFAMILY SSF161098 96 285 3.4E-25 T 12-10-2018 IPR035906 MetI-like superfamily TL08_11465 6e3ac82e6df1ffc484c13f0e24475504 139 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 2 133 23.231 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 TL08_11465 6e3ac82e6df1ffc484c13f0e24475504 139 SUPERFAMILY SSF48013 3 128 4.06E-38 T 12-10-2018 IPR035926 NusB-like superfamily TL08_11465 6e3ac82e6df1ffc484c13f0e24475504 139 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 3 130 1.9E-40 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 TL08_11465 6e3ac82e6df1ffc484c13f0e24475504 139 Gene3D G3DSA:1.10.940.10 1 128 2.2E-43 T 12-10-2018 IPR035926 NusB-like superfamily TL08_11465 6e3ac82e6df1ffc484c13f0e24475504 139 Pfam PF01029 NusB family 6 130 7.8E-35 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TL08_24650 5734b9be3ca11d015c6e1320d237b319 845 Gene3D G3DSA:1.10.486.10 427 589 1.7E-41 T 12-10-2018 TL08_24650 5734b9be3ca11d015c6e1320d237b319 845 Gene3D G3DSA:3.40.50.300 322 426 4.1E-36 T 12-10-2018 TL08_24650 5734b9be3ca11d015c6e1320d237b319 845 SUPERFAMILY SSF52540 25 731 6.84E-169 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24650 5734b9be3ca11d015c6e1320d237b319 845 Pfam PF13361 UvrD-like helicase C-terminal domain 319 702 2.7E-60 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TL08_24650 5734b9be3ca11d015c6e1320d237b319 845 Gene3D G3DSA:1.10.10.1560 655 730 1.3E-27 T 12-10-2018 TL08_24650 5734b9be3ca11d015c6e1320d237b319 845 Gene3D G3DSA:3.40.50.300 30 315 1.4E-94 T 12-10-2018 TL08_24650 5734b9be3ca11d015c6e1320d237b319 845 Gene3D G3DSA:1.10.10.160 142 221 1.4E-94 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily TL08_24650 5734b9be3ca11d015c6e1320d237b319 845 Pfam PF00580 UvrD/REP helicase N-terminal domain 30 313 2.1E-75 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TL08_04225 5bad3c18ff44547e039252bd9310b64c 386 Pfam PF00149 Calcineurin-like phosphoesterase 1 221 2.6E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_04225 5bad3c18ff44547e039252bd9310b64c 386 Gene3D G3DSA:3.60.21.10 1 270 7.8E-85 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TL08_04225 5bad3c18ff44547e039252bd9310b64c 386 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 247 4.3E-49 T 12-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 TL08_04225 5bad3c18ff44547e039252bd9310b64c 386 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 270 356 2.1E-7 T 12-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain TL08_04225 5bad3c18ff44547e039252bd9310b64c 386 SUPERFAMILY SSF56300 1 283 3.01E-52 T 12-10-2018 TL08_03855 983149d15e3c9237cbcd9293cb8c9742 259 Pfam PF12811 Bax inhibitor 1 like 34 258 6.4E-85 T 12-10-2018 IPR010539 Protein of unknown function UCP009160 TL08_03855 983149d15e3c9237cbcd9293cb8c9742 259 PIRSF PIRSF009160 1 259 3.3E-79 T 12-10-2018 IPR010539 Protein of unknown function UCP009160 TL08_24920 b036011475628c9adbb04c8548193335 201 Gene3D G3DSA:3.30.230.10 74 201 7.5E-49 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TL08_24920 b036011475628c9adbb04c8548193335 201 Pfam PF00380 Ribosomal protein S9/S16 81 201 2.6E-43 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TL08_24920 b036011475628c9adbb04c8548193335 201 SUPERFAMILY SSF54211 77 201 6.45E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_24920 b036011475628c9adbb04c8548193335 201 ProSitePatterns PS00360 Ribosomal protein S9 signature. 140 158 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TL08_24920 b036011475628c9adbb04c8548193335 201 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 72 201 32.303 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid TL08_13270 7d29af43d1cc3f20e9cdd56e5df38066 434 Gene3D G3DSA:3.40.190.10 150 423 1.0E-117 T 12-10-2018 TL08_13270 7d29af43d1cc3f20e9cdd56e5df38066 434 Pfam PF13416 Bacterial extracellular solute-binding protein 58 360 3.3E-25 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_13270 7d29af43d1cc3f20e9cdd56e5df38066 434 SUPERFAMILY SSF53850 37 431 2.67E-57 T 12-10-2018 TL08_13270 7d29af43d1cc3f20e9cdd56e5df38066 434 Gene3D G3DSA:3.40.190.10 40 378 1.0E-117 T 12-10-2018 TL08_09135 f1fe5db9d85a6e989da2a36d57bea68a 378 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 46 369 5.9E-137 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 TL08_09135 f1fe5db9d85a6e989da2a36d57bea68a 378 SUPERFAMILY SSF51679 45 369 1.09E-82 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_09135 f1fe5db9d85a6e989da2a36d57bea68a 378 Pfam PF00296 Luciferase-like monooxygenase 58 346 3.3E-37 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_09135 f1fe5db9d85a6e989da2a36d57bea68a 378 Gene3D G3DSA:3.20.20.30 41 375 1.5E-113 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_11690 dec981c4c5e927db52d2b502daa12185 546 Pfam PF00342 Phosphoglucose isomerase 86 289 2.6E-7 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11690 dec981c4c5e927db52d2b502daa12185 546 Gene3D G3DSA:3.40.50.10490 53 217 6.9E-34 T 12-10-2018 TL08_11690 dec981c4c5e927db52d2b502daa12185 546 Gene3D G3DSA:3.40.50.10490 218 303 2.7E-10 T 12-10-2018 TL08_11690 dec981c4c5e927db52d2b502daa12185 546 Gene3D G3DSA:3.40.50.10490 329 380 7.3E-10 T 12-10-2018 TL08_11690 dec981c4c5e927db52d2b502daa12185 546 SUPERFAMILY SSF53697 41 376 1.06E-70 T 12-10-2018 TL08_11690 dec981c4c5e927db52d2b502daa12185 546 PRINTS PR00662 Glucose-6-phosphate isomerase signature 267 288 2.4E-9 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11690 dec981c4c5e927db52d2b502daa12185 546 PRINTS PR00662 Glucose-6-phosphate isomerase signature 89 108 2.4E-9 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_11690 dec981c4c5e927db52d2b502daa12185 546 PRINTS PR00662 Glucose-6-phosphate isomerase signature 193 211 2.4E-9 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TL08_22690 46209459e5f8380ea1f2396e94f85bac 551 Pfam PF00682 HMGL-like 16 268 1.2E-37 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TL08_22690 46209459e5f8380ea1f2396e94f85bac 551 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 16 548 8.3E-174 T 12-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 TL08_22690 46209459e5f8380ea1f2396e94f85bac 551 SUPERFAMILY SSF110921 423 539 7.98E-25 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_22690 46209459e5f8380ea1f2396e94f85bac 551 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 22 38 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_22690 46209459e5f8380ea1f2396e94f85bac 551 Gene3D G3DSA:3.30.160.270 414 541 9.1E-8 T 12-10-2018 TL08_22690 46209459e5f8380ea1f2396e94f85bac 551 SMART SM00917 387 543 4.0E-37 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_22690 46209459e5f8380ea1f2396e94f85bac 551 Pfam PF08502 LeuA allosteric (dimerisation) domain 388 539 1.8E-24 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TL08_22690 46209459e5f8380ea1f2396e94f85bac 551 SUPERFAMILY SSF51569 11 305 7.69E-71 T 12-10-2018 TL08_22690 46209459e5f8380ea1f2396e94f85bac 551 Gene3D G3DSA:3.20.20.70 15 337 1.0E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_15565 d7c90dcd42857f3e0f6f12386ec77a9e 296 SUPERFAMILY SSF56349 114 295 4.41E-36 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_15565 d7c90dcd42857f3e0f6f12386ec77a9e 296 Gene3D G3DSA:1.10.150.130 11 117 5.6E-9 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_15565 d7c90dcd42857f3e0f6f12386ec77a9e 296 Pfam PF00589 Phage integrase family 117 288 9.3E-31 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_15565 d7c90dcd42857f3e0f6f12386ec77a9e 296 SUPERFAMILY SSF47823 18 102 4.32E-6 T 12-10-2018 TL08_15565 d7c90dcd42857f3e0f6f12386ec77a9e 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 97 1.4E-5 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TL08_15565 d7c90dcd42857f3e0f6f12386ec77a9e 296 Gene3D G3DSA:1.10.443.10 118 296 2.2E-38 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TL08_17925 6d3b28cecf42737e4978744ac3bf8b4a 335 Pfam PF12706 Beta-lactamase superfamily domain 82 272 6.0E-48 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_17925 6d3b28cecf42737e4978744ac3bf8b4a 335 SUPERFAMILY SSF56281 57 288 3.41E-37 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_17925 6d3b28cecf42737e4978744ac3bf8b4a 335 PIRSF PIRSF038896 7 316 7.3E-101 T 12-10-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 TL08_17925 6d3b28cecf42737e4978744ac3bf8b4a 335 Gene3D G3DSA:3.60.15.10 53 315 3.0E-81 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_06465 4ea6ef4e289cd2506557cd8b01b1c3a8 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 9.8E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06465 4ea6ef4e289cd2506557cd8b01b1c3a8 198 SUPERFAMILY SSF48498 85 189 1.04E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_06465 4ea6ef4e289cd2506557cd8b01b1c3a8 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06465 4ea6ef4e289cd2506557cd8b01b1c3a8 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06465 4ea6ef4e289cd2506557cd8b01b1c3a8 198 SUPERFAMILY SSF46689 16 85 3.23E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06465 4ea6ef4e289cd2506557cd8b01b1c3a8 198 Gene3D G3DSA:1.10.357.10 9 196 4.7E-59 T 12-10-2018 TL08_26770 3a926425f9a1ba826e8ad296eee15e12 293 Pfam PF13460 NAD(P)H-binding 9 143 1.1E-12 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_26770 3a926425f9a1ba826e8ad296eee15e12 293 Gene3D G3DSA:3.40.50.720 4 272 1.4E-47 T 12-10-2018 TL08_26770 3a926425f9a1ba826e8ad296eee15e12 293 SUPERFAMILY SSF51735 2 250 2.73E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_26770 3a926425f9a1ba826e8ad296eee15e12 293 Gene3D G3DSA:3.90.25.10 142 264 1.4E-47 T 12-10-2018 TL08_21575 f8e33795dfc383b7725da0ffaf770df5 68 Gene3D G3DSA:2.40.50.140 1 54 4.1E-5 T 12-10-2018 TL08_16370 9f86b249dc47812fa490b7a389be0503 71 Gene3D G3DSA:3.90.820.10 1 70 3.0E-35 T 12-10-2018 TL08_16370 9f86b249dc47812fa490b7a389be0503 71 Pfam PF03621 MbtH-like protein 2 54 4.3E-27 T 12-10-2018 IPR005153 MbtH-like domain TL08_16370 9f86b249dc47812fa490b7a389be0503 71 SMART SM00923 4 54 4.6E-30 T 12-10-2018 IPR005153 MbtH-like domain TL08_16370 9f86b249dc47812fa490b7a389be0503 71 SUPERFAMILY SSF160582 3 70 3.66E-30 T 12-10-2018 IPR038020 MbtH-like domain superfamily TL08_22200 823e2c1bca1f367ccabf5274662391d8 213 SUPERFAMILY SSF55729 22 200 6.25E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_22200 823e2c1bca1f367ccabf5274662391d8 213 Gene3D G3DSA:3.40.630.30 14 211 1.1E-31 T 12-10-2018 TL08_22200 823e2c1bca1f367ccabf5274662391d8 213 Pfam PF13302 Acetyltransferase (GNAT) domain 29 175 5.8E-14 T 12-10-2018 IPR000182 GNAT domain TL08_19905 283ec46312d50ab88f0a011a393d9e02 135 Gene3D G3DSA:3.10.180.10 1 134 4.2E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_19905 283ec46312d50ab88f0a011a393d9e02 135 SUPERFAMILY SSF54593 1 120 1.16E-11 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_08440 2b6afd692d26b6e9b6b99801cbe0f29e 671 Pfam PF13520 Amino acid permease 56 459 2.7E-26 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TL08_27070 1127aa03c773eb9c0ff7c6e4b50e0781 537 SUPERFAMILY SSF56112 34 254 7.68E-11 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_27070 1127aa03c773eb9c0ff7c6e4b50e0781 537 Gene3D G3DSA:1.10.510.10 130 286 1.7E-37 T 12-10-2018 TL08_27070 1127aa03c773eb9c0ff7c6e4b50e0781 537 Gene3D G3DSA:3.30.200.20 25 129 1.8E-21 T 12-10-2018 TL08_02265 1f060f0288b279ed44817eae15da766d 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 32 49 1.7E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_02265 1f060f0288b279ed44817eae15da766d 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 1.7E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_02265 1f060f0288b279ed44817eae15da766d 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 1.7E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_02265 1f060f0288b279ed44817eae15da766d 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 1.7E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_02265 1f060f0288b279ed44817eae15da766d 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 1.7E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_02265 1f060f0288b279ed44817eae15da766d 271 Gene3D G3DSA:3.40.50.720 24 270 4.1E-61 T 12-10-2018 TL08_02265 1f060f0288b279ed44817eae15da766d 271 SUPERFAMILY SSF51735 29 259 2.6E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_02265 1f060f0288b279ed44817eae15da766d 271 Pfam PF00106 short chain dehydrogenase 32 208 1.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05305 cb983decfc64c75f02813efd2446258c 287 SMART SM00382 30 216 3.2E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_05305 cb983decfc64c75f02813efd2446258c 287 SUPERFAMILY SSF52540 3 220 3.79E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05305 cb983decfc64c75f02813efd2446258c 287 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_05305 cb983decfc64c75f02813efd2446258c 287 Pfam PF00005 ABC transporter 22 161 5.7E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_05305 cb983decfc64c75f02813efd2446258c 287 Gene3D G3DSA:3.40.50.300 1 240 1.9E-57 T 12-10-2018 TL08_12730 3d0275989d3726f70f560d43697422b3 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 284 1.3E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_25120 2b817cc159364380b782b21c3116e446 308 SUPERFAMILY SSF74650 12 303 2.26E-56 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TL08_25120 2b817cc159364380b782b21c3116e446 308 Pfam PF01263 Aldose 1-epimerase 15 301 1.5E-40 T 12-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 TL08_25120 2b817cc159364380b782b21c3116e446 308 Gene3D G3DSA:2.70.98.10 14 307 1.6E-71 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TL08_14475 b451bb943b6656e7f04859126d5d6484 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 259 2.8E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_14475 b451bb943b6656e7f04859126d5d6484 270 SUPERFAMILY SSF161098 69 246 3.79E-14 T 12-10-2018 IPR035906 MetI-like superfamily TL08_14475 b451bb943b6656e7f04859126d5d6484 270 Gene3D G3DSA:1.10.3720.10 60 260 7.3E-12 T 12-10-2018 IPR035906 MetI-like superfamily TL08_24040 e8b66c57b794f3098011e441fa7e36a1 331 Gene3D G3DSA:3.20.20.100 7 327 4.0E-119 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_24040 e8b66c57b794f3098011e441fa7e36a1 331 SUPERFAMILY SSF51430 9 312 6.68E-100 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_24040 e8b66c57b794f3098011e441fa7e36a1 331 Pfam PF00248 Aldo/keto reductase family 21 310 8.0E-75 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_03205 c82478c6bde8f0449c826550f22d6dec 112 Gene3D G3DSA:3.30.70.100 1 102 9.8E-27 T 12-10-2018 TL08_03205 c82478c6bde8f0449c826550f22d6dec 112 Pfam PF07110 EthD domain 13 82 1.9E-7 T 12-10-2018 IPR009799 EthD domain TL08_03205 c82478c6bde8f0449c826550f22d6dec 112 SUPERFAMILY SSF54909 1 97 1.99E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_03205 c82478c6bde8f0449c826550f22d6dec 112 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 97 1.8E-15 T 12-10-2018 IPR009799 EthD domain TL08_07095 9bd346921e02eb00ae274051bd5dd99a 250 SUPERFAMILY SSF52540 1 219 3.75E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07095 9bd346921e02eb00ae274051bd5dd99a 250 SMART SM00382 26 204 1.5E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_07095 9bd346921e02eb00ae274051bd5dd99a 250 Pfam PF00005 ABC transporter 18 156 2.1E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_07095 9bd346921e02eb00ae274051bd5dd99a 250 Gene3D G3DSA:3.40.50.300 1 232 7.0E-54 T 12-10-2018 TL08_10215 cf6a5b83819abfd579334cd9b59e56db 157 Pfam PF03061 Thioesterase superfamily 61 137 2.1E-15 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TL08_10215 cf6a5b83819abfd579334cd9b59e56db 157 SUPERFAMILY SSF54637 33 150 1.57E-28 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_10215 cf6a5b83819abfd579334cd9b59e56db 157 Gene3D G3DSA:3.10.129.10 12 150 2.6E-45 T 12-10-2018 TL08_10215 cf6a5b83819abfd579334cd9b59e56db 157 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 32 145 2.8E-30 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TL08_10660 926dfe230ee4ff4f39c7d32db4ca14f0 298 SUPERFAMILY SSF81345 9 272 1.44E-17 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_10660 926dfe230ee4ff4f39c7d32db4ca14f0 298 Pfam PF00950 ABC 3 transport family 9 274 1.3E-41 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TL08_21580 04ba97403081d7401c8bb197cb07bf0c 497 Pfam PF01145 SPFH domain / Band 7 family 29 215 4.2E-20 T 12-10-2018 IPR001107 Band 7 domain TL08_21580 04ba97403081d7401c8bb197cb07bf0c 497 Gene3D G3DSA:3.30.479.30 76 190 1.0E-24 T 12-10-2018 TL08_21580 04ba97403081d7401c8bb197cb07bf0c 497 Pfam PF15975 Flotillin 364 466 1.7E-10 T 12-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 TL08_21580 04ba97403081d7401c8bb197cb07bf0c 497 SUPERFAMILY SSF117892 67 204 4.58E-24 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily TL08_22685 a0b1f7aaff7a849f3c9bf1aebbd25cef 257 SUPERFAMILY SSF56529 52 255 8.24E-79 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TL08_22685 a0b1f7aaff7a849f3c9bf1aebbd25cef 257 Gene3D G3DSA:3.90.850.10 56 257 6.9E-85 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TL08_22685 a0b1f7aaff7a849f3c9bf1aebbd25cef 257 Pfam PF10370 Domain of unknown function (DUF2437) 2 55 4.0E-13 T 12-10-2018 IPR018833 Domain of unknown function DUF2437 TL08_22685 a0b1f7aaff7a849f3c9bf1aebbd25cef 257 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 60 255 1.8E-67 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TL08_22685 a0b1f7aaff7a849f3c9bf1aebbd25cef 257 Gene3D G3DSA:2.30.30.370 1 55 2.4E-28 T 12-10-2018 TL08_19435 1b3da9203d7def89cd6764ae9c63d153 110 Pfam PF09900 Predicted membrane protein (DUF2127) 11 92 4.6E-16 T 12-10-2018 IPR021125 Protein of unknown function DUF2127 TL08_12060 04ca7fcf172724bf71e07ed8b7624011 65 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 34 65 1.0E-20 T 12-10-2018 IPR008515 Ubiquitin-like, Pup TL08_12060 04ca7fcf172724bf71e07ed8b7624011 65 Pfam PF05639 Pup-like protein 3 65 7.6E-23 T 12-10-2018 IPR008515 Ubiquitin-like, Pup TL08_12060 04ca7fcf172724bf71e07ed8b7624011 65 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 65 16.937 T 12-10-2018 IPR008515 Ubiquitin-like, Pup TL08_16190 c5c0299ca57bcd1d672b11abf9e99834 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 1.3E-9 T 12-10-2018 TL08_16190 c5c0299ca57bcd1d672b11abf9e99834 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 1.3E-9 T 12-10-2018 TL08_16190 c5c0299ca57bcd1d672b11abf9e99834 512 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.3E-9 T 12-10-2018 TL08_16190 c5c0299ca57bcd1d672b11abf9e99834 512 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 433 2.5E-83 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TL08_16190 c5c0299ca57bcd1d672b11abf9e99834 512 Pfam PF07690 Major Facilitator Superfamily 29 425 7.0E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_16190 c5c0299ca57bcd1d672b11abf9e99834 512 Gene3D G3DSA:1.20.1250.20 279 479 1.5E-19 T 12-10-2018 TL08_16190 c5c0299ca57bcd1d672b11abf9e99834 512 Gene3D G3DSA:1.20.1720.10 24 271 1.2E-40 T 12-10-2018 TL08_16190 c5c0299ca57bcd1d672b11abf9e99834 512 SUPERFAMILY SSF103473 14 475 9.29E-60 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 Pfam PF01238 Phosphomannose isomerase type I 7 306 3.4E-57 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 PIRSF PIRSF001480 1 431 2.0E-92 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 PRINTS PR00714 Phosphomannose isomerase type I signature 85 106 1.4E-61 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 PRINTS PR00714 Phosphomannose isomerase type I signature 35 50 1.4E-61 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 PRINTS PR00714 Phosphomannose isomerase type I signature 130 153 1.4E-61 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 PRINTS PR00714 Phosphomannose isomerase type I signature 286 305 1.4E-61 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 PRINTS PR00714 Phosphomannose isomerase type I signature 232 247 1.4E-61 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 PRINTS PR00714 Phosphomannose isomerase type I signature 267 286 1.4E-61 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 PRINTS PR00714 Phosphomannose isomerase type I signature 248 267 1.4E-61 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 PRINTS PR00714 Phosphomannose isomerase type I signature 7 25 1.4E-61 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 SUPERFAMILY SSF51182 6 407 9.89E-90 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 7 348 3.4E-62 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 Gene3D G3DSA:2.60.120.10 9 287 2.0E-126 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 Gene3D G3DSA:2.60.120.10 313 411 2.0E-126 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_23340 eb751f9bc0c21418843f7106c87cffd6 431 Gene3D G3DSA:1.10.441.10 154 312 2.0E-126 T 12-10-2018 TL08_19860 4f2c50d8bfe5dd5441c1113b1506d7ed 600 Gene3D G3DSA:3.40.50.1110 163 343 2.3E-13 T 12-10-2018 IPR036514 SGNH hydrolase superfamily TL08_19860 4f2c50d8bfe5dd5441c1113b1506d7ed 600 SUPERFAMILY SSF52266 185 345 4.65E-17 T 12-10-2018 TL08_19860 4f2c50d8bfe5dd5441c1113b1506d7ed 600 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 184 335 3.5E-9 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain TL08_18310 f4eeea5a09b03f0b7fb3cbc9a35e5d85 65 Pfam PF04149 Domain of unknown function (DUF397) 9 60 5.3E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_22325 0cbaf1ea73fe94256e15272650d0b9b9 260 Pfam PF12483 E3 Ubiquitin ligase 95 250 2.2E-26 T 12-10-2018 IPR022170 E3 Ubiquitin ligase, GIDE-type GO:0004842|GO:0006996|GO:0016567 MetaCyc: PWY-7511|Reactome: R-HSA-5689880 TL08_16435 936fe43778b95267a77a1a8aad70f64b 280 Pfam PF13560 Helix-turn-helix domain 9 71 1.5E-14 T 12-10-2018 TL08_16435 936fe43778b95267a77a1a8aad70f64b 280 SMART SM00530 13 68 2.8E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_16435 936fe43778b95267a77a1a8aad70f64b 280 Gene3D G3DSA:1.10.260.40 4 71 2.7E-11 T 12-10-2018 TL08_16435 936fe43778b95267a77a1a8aad70f64b 280 SUPERFAMILY SSF47413 9 63 6.66E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_24845 3bb8b351e988384525f3c73d6c108042 188 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 43 166 3.3E-29 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TL08_24845 3bb8b351e988384525f3c73d6c108042 188 Gene3D G3DSA:3.40.50.300 35 186 1.6E-32 T 12-10-2018 TL08_24845 3bb8b351e988384525f3c73d6c108042 188 SUPERFAMILY SSF52540 59 163 2.73E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_24845 3bb8b351e988384525f3c73d6c108042 188 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 45 175 3.4E-22 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TL08_26750 61de436a807bbd76203d0111969f7fff 354 SUPERFAMILY SSF52518 33 212 8.03E-65 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_26750 61de436a807bbd76203d0111969f7fff 354 Gene3D G3DSA:3.40.50.920 229 350 8.6E-43 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_26750 61de436a807bbd76203d0111969f7fff 354 SMART SM00861 34 209 4.9E-69 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_26750 61de436a807bbd76203d0111969f7fff 354 Pfam PF02780 Transketolase, C-terminal domain 226 344 6.2E-35 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TL08_26750 61de436a807bbd76203d0111969f7fff 354 Gene3D G3DSA:3.40.50.970 30 228 7.1E-77 T 12-10-2018 TL08_26750 61de436a807bbd76203d0111969f7fff 354 Pfam PF02779 Transketolase, pyrimidine binding domain 33 208 6.6E-43 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_26750 61de436a807bbd76203d0111969f7fff 354 SUPERFAMILY SSF52922 219 352 9.16E-37 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_01255 d16d34dfb434709db900891cd80eea70 304 Gene3D G3DSA:3.40.50.720 2 147 3.9E-34 T 12-10-2018 TL08_01255 d16d34dfb434709db900891cd80eea70 304 SUPERFAMILY SSF51735 7 156 2.37E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_01255 d16d34dfb434709db900891cd80eea70 304 SUPERFAMILY SSF55347 154 251 7.85E-9 T 12-10-2018 TL08_01255 d16d34dfb434709db900891cd80eea70 304 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 121 2.5E-21 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_01255 d16d34dfb434709db900891cd80eea70 304 Gene3D G3DSA:3.30.360.10 149 304 1.8E-14 T 12-10-2018 TL08_26745 b931088151e2d62b9122535649a9b671 413 Pfam PF00676 Dehydrogenase E1 component 82 360 2.8E-70 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TL08_26745 b931088151e2d62b9122535649a9b671 413 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 52 398 6.8E-129 T 12-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TL08_26745 b931088151e2d62b9122535649a9b671 413 SUPERFAMILY SSF52518 49 402 9.77E-96 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_26745 b931088151e2d62b9122535649a9b671 413 Gene3D G3DSA:3.40.50.970 21 399 4.8E-114 T 12-10-2018 TL08_13980 e7903fa2c766708d275f54276bfefcfa 132 Gene3D G3DSA:3.30.1330.40 4 132 1.2E-30 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_13980 e7903fa2c766708d275f54276bfefcfa 132 Pfam PF01042 Endoribonuclease L-PSP 15 130 2.5E-21 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TL08_13980 e7903fa2c766708d275f54276bfefcfa 132 SUPERFAMILY SSF55298 1 131 5.97E-28 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_02680 2e3180a8a39d8465d31cd66ce0db7b14 331 SUPERFAMILY SSF103481 223 300 3.66E-8 T 12-10-2018 TL08_02680 2e3180a8a39d8465d31cd66ce0db7b14 331 SUPERFAMILY SSF103481 60 161 3.01E-11 T 12-10-2018 TL08_02680 2e3180a8a39d8465d31cd66ce0db7b14 331 TIGRFAM TIGR00688 rarD: protein RarD 27 275 3.1E-54 T 12-10-2018 IPR004626 RarD protein GO:0005887 TL08_02680 2e3180a8a39d8465d31cd66ce0db7b14 331 Pfam PF00892 EamA-like transporter family 26 160 1.9E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_12295 7f0b759ca251ed3ef5f97bebcc183dd1 305 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 15 263 1.1E-68 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain TL08_12295 7f0b759ca251ed3ef5f97bebcc183dd1 305 Gene3D G3DSA:3.90.920.30 21 303 2.3E-85 T 12-10-2018 TL08_13855 b8a9f8eda8b241e75ea165e7ba44e8fd 210 Gene3D G3DSA:3.30.230.30 1 129 6.0E-49 T 12-10-2018 IPR036956 Impact, N-terminal domain superfamily TL08_13855 b8a9f8eda8b241e75ea165e7ba44e8fd 210 SUPERFAMILY SSF54211 3 131 4.17E-41 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TL08_13855 b8a9f8eda8b241e75ea165e7ba44e8fd 210 SUPERFAMILY SSF54980 137 200 1.37E-10 T 12-10-2018 IPR035647 EF-G domain III/V-like TL08_13855 b8a9f8eda8b241e75ea165e7ba44e8fd 210 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 12-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site TL08_13855 b8a9f8eda8b241e75ea165e7ba44e8fd 210 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 3.4E-14 T 12-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal TL08_13855 b8a9f8eda8b241e75ea165e7ba44e8fd 210 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 202 4.7E-56 T 12-10-2018 IPR015796 Impact family, bacterial/archaeal TL08_13855 b8a9f8eda8b241e75ea165e7ba44e8fd 210 Pfam PF01205 Uncharacterized protein family UPF0029 19 122 6.5E-30 T 12-10-2018 IPR001498 Impact, N-terminal TL08_05930 8e1c63acbe02d93ac3bd3d46ed88f1f8 424 SUPERFAMILY SSF53383 21 416 4.54E-71 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_05930 8e1c63acbe02d93ac3bd3d46ed88f1f8 424 Gene3D G3DSA:3.40.640.10 14 272 1.6E-71 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_05930 8e1c63acbe02d93ac3bd3d46ed88f1f8 424 Gene3D G3DSA:3.90.1150.10 273 420 4.6E-25 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_05930 8e1c63acbe02d93ac3bd3d46ed88f1f8 424 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 26 413 1.8E-85 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TL08_04320 766ed84a9115026e93e4a749cbcea1fa 176 SUPERFAMILY SSF82607 23 113 1.01E-8 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_04320 766ed84a9115026e93e4a749cbcea1fa 176 Gene3D G3DSA:3.30.1310.10 17 121 2.4E-11 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_04320 766ed84a9115026e93e4a749cbcea1fa 176 Pfam PF02575 YbaB/EbfC DNA-binding family 26 114 1.5E-13 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_24660 3e24ac304a9a197dd59819fdea386bb5 103 SUPERFAMILY SSF48600 18 79 3.21E-13 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TL08_24660 3e24ac304a9a197dd59819fdea386bb5 103 Pfam PF01817 Chorismate mutase type II 25 79 1.9E-10 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TL08_24660 3e24ac304a9a197dd59819fdea386bb5 103 Gene3D G3DSA:1.20.59.10 14 97 8.5E-27 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TL08_24660 3e24ac304a9a197dd59819fdea386bb5 103 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 20 93 2.0E-29 T 12-10-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal TL08_24660 3e24ac304a9a197dd59819fdea386bb5 103 SMART SM00830 25 87 7.2E-8 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TL08_24305 0f10ca0a4cc9a51fd3d8e292b84bd6a1 297 Pfam PF00171 Aldehyde dehydrogenase family 33 263 2.1E-40 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_24305 0f10ca0a4cc9a51fd3d8e292b84bd6a1 297 SUPERFAMILY SSF53720 15 263 1.83E-45 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_24305 0f10ca0a4cc9a51fd3d8e292b84bd6a1 297 Gene3D G3DSA:3.40.605.10 10 295 1.0E-53 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_13420 16487d557c869b73e87f875f0d3b8244 343 Pfam PF01494 FAD binding domain 5 61 4.6E-6 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_13420 16487d557c869b73e87f875f0d3b8244 343 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 8.5E-13 T 12-10-2018 TL08_13420 16487d557c869b73e87f875f0d3b8244 343 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 135 150 8.5E-13 T 12-10-2018 TL08_13420 16487d557c869b73e87f875f0d3b8244 343 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 250 265 8.5E-13 T 12-10-2018 TL08_13420 16487d557c869b73e87f875f0d3b8244 343 Gene3D G3DSA:3.50.50.60 2 340 8.5E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_13420 16487d557c869b73e87f875f0d3b8244 343 SUPERFAMILY SSF51905 5 312 4.1E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_14610 e4f55ecb2e9bec237a4f4ba6aa9b946a 178 Pfam PF07617 Protein of unknown function (DUF1579) 49 160 2.1E-4 T 12-10-2018 IPR011473 Protein of unknown function DUF1579 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00463 E-class P450 group I signature 38 57 2.7E-17 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00463 E-class P450 group I signature 268 294 2.7E-17 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00463 E-class P450 group I signature 248 265 2.7E-17 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00463 E-class P450 group I signature 298 316 2.7E-17 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00463 E-class P450 group I signature 371 381 2.7E-17 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00463 E-class P450 group I signature 339 363 2.7E-17 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00463 E-class P450 group I signature 381 404 2.7E-17 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 Pfam PF00067 Cytochrome P450 28 415 5.4E-56 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 374 383 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 Gene3D G3DSA:1.10.630.10 3 431 7.1E-82 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 SUPERFAMILY SSF48264 28 434 1.7E-80 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00385 P450 superfamily signature 259 276 2.3E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00385 P450 superfamily signature 299 310 2.3E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00385 P450 superfamily signature 372 381 2.3E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16005 e5f04537aca4dc7061af9b2604fc72b1 435 PRINTS PR00385 P450 superfamily signature 381 392 2.3E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_13575 13e8d1500d6aa6e42862977c9318c247 422 Pfam PF04143 Sulphur transport 74 402 3.2E-61 T 12-10-2018 IPR007272 Sulphur transport domain TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 SUPERFAMILY SSF51735 2 199 2.18E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 3.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 3.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 3.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.5E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.5E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.5E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.5E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 Pfam PF00106 short chain dehydrogenase 5 186 4.4E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14725 1c9ea2f24ffab74c1d867a7b805a68bc 281 Gene3D G3DSA:3.40.50.720 5 263 2.2E-55 T 12-10-2018 TL08_03915 48ab30038db993350cbdf828f80d15b3 349 SUPERFAMILY SSF75005 30 348 9.42E-72 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_03915 48ab30038db993350cbdf828f80d15b3 349 PIRSF PIRSF026534 34 349 2.9E-94 T 12-10-2018 IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase GO:0046558 TL08_03915 48ab30038db993350cbdf828f80d15b3 349 Gene3D G3DSA:2.115.10.20 51 348 2.6E-85 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_03915 48ab30038db993350cbdf828f80d15b3 349 Pfam PF04616 Glycosyl hydrolases family 43 66 346 5.2E-50 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 TL08_13190 3a4513741232a2f649fda6daddc2baed 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 4.4E-24 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TL08_13190 3a4513741232a2f649fda6daddc2baed 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 213 231 4.4E-24 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TL08_13190 3a4513741232a2f649fda6daddc2baed 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 4.4E-24 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TL08_13190 3a4513741232a2f649fda6daddc2baed 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 244 265 4.4E-24 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TL08_13190 3a4513741232a2f649fda6daddc2baed 412 Gene3D G3DSA:1.20.120.640 330 412 6.9E-26 T 12-10-2018 TL08_13190 3a4513741232a2f649fda6daddc2baed 412 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 412 53.951 T 12-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 TL08_13190 3a4513741232a2f649fda6daddc2baed 412 SUPERFAMILY SSF52374 29 334 1.15E-69 T 12-10-2018 TL08_13190 3a4513741232a2f649fda6daddc2baed 412 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 36 334 5.2E-84 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TL08_13190 3a4513741232a2f649fda6daddc2baed 412 Gene3D G3DSA:3.40.50.620 1 329 4.8E-104 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TL08_13190 3a4513741232a2f649fda6daddc2baed 412 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 3 412 6.1E-210 T 12-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 TL08_00830 44ee928a77e6d92fb2140dbbe51c6e87 158 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 10 154 2.5E-47 T 12-10-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative TL08_20800 888851ac90566f3ebf5bf94f95b5fa81 129 SMART SM00418 2 84 2.1E-16 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_20800 888851ac90566f3ebf5bf94f95b5fa81 129 Pfam PF01022 Bacterial regulatory protein, arsR family 9 58 3.0E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_20800 888851ac90566f3ebf5bf94f95b5fa81 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 4.0E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_20800 888851ac90566f3ebf5bf94f95b5fa81 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 4.0E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_20800 888851ac90566f3ebf5bf94f95b5fa81 129 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 4.0E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_20800 888851ac90566f3ebf5bf94f95b5fa81 129 SUPERFAMILY SSF46785 3 100 9.54E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_20800 888851ac90566f3ebf5bf94f95b5fa81 129 Gene3D G3DSA:1.10.10.10 1 108 1.4E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07010 6140be5f96cb03acac7d5fc48fb1a79c 687 SUPERFAMILY SSF51445 160 675 9.19E-134 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_07010 6140be5f96cb03acac7d5fc48fb1a79c 687 Gene3D G3DSA:3.20.20.80 156 675 9.4E-124 T 12-10-2018 TL08_07010 6140be5f96cb03acac7d5fc48fb1a79c 687 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 127 671 9.1E-92 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TL08_07010 6140be5f96cb03acac7d5fc48fb1a79c 687 Pfam PF02446 4-alpha-glucanotransferase 165 663 1.4E-112 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TL08_11010 19ad8a0ad86d506f7bf699eea7cccd78 384 SUPERFAMILY SSF81606 97 374 3.4E-35 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_11010 19ad8a0ad86d506f7bf699eea7cccd78 384 SMART SM00332 86 372 4.4E-5 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_11010 19ad8a0ad86d506f7bf699eea7cccd78 384 Pfam PF13672 Protein phosphatase 2C 107 328 4.4E-12 T 12-10-2018 TL08_07595 df5d575efd136e69fa332c9bab90cb35 552 Pfam PF01547 Bacterial extracellular solute-binding protein 128 368 5.5E-13 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_07595 df5d575efd136e69fa332c9bab90cb35 552 SUPERFAMILY SSF53850 35 549 1.32E-56 T 12-10-2018 TL08_08905 958b89a3973236ab484f4e259cece9d0 161 Gene3D G3DSA:3.40.1050.10 1 161 4.9E-62 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TL08_08905 958b89a3973236ab484f4e259cece9d0 161 SUPERFAMILY SSF53056 1 160 3.4E-36 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 TL08_08905 958b89a3973236ab484f4e259cece9d0 161 Pfam PF00484 Carbonic anhydrase 31 100 2.9E-12 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TL08_08905 958b89a3973236ab484f4e259cece9d0 161 SMART SM00947 23 161 4.3E-27 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TL08_14210 f5f602c0f5aa47d9578b27c13e9c7ec0 140 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 136 1.4E-20 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like TL08_14210 f5f602c0f5aa47d9578b27c13e9c7ec0 140 SUPERFAMILY SSF55961 5 138 1.65E-31 T 12-10-2018 TL08_14210 f5f602c0f5aa47d9578b27c13e9c7ec0 140 Gene3D G3DSA:3.30.530.20 1 140 3.0E-34 T 12-10-2018 IPR023393 START-like domain superfamily TL08_24615 880d562cb3066c92340a803f9c2c5e33 255 Pfam PF01551 Peptidase family M23 149 244 3.4E-30 T 12-10-2018 IPR016047 Peptidase M23 TL08_24615 880d562cb3066c92340a803f9c2c5e33 255 SUPERFAMILY SSF51261 117 248 2.82E-45 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_24615 880d562cb3066c92340a803f9c2c5e33 255 Gene3D G3DSA:2.70.70.10 93 251 1.0E-41 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_15200 7d9ff8eca73d14e5e65e85309808dcd0 264 Gene3D G3DSA:2.60.120.200 25 259 5.3E-23 T 12-10-2018 TL08_15200 7d9ff8eca73d14e5e65e85309808dcd0 264 SUPERFAMILY SSF49899 23 247 3.02E-19 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TL08_15200 7d9ff8eca73d14e5e65e85309808dcd0 264 Pfam PF00722 Glycosyl hydrolases family 16 67 242 5.0E-7 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 TL08_26760 b4d7884765552b50723c50ee478fc994 188 Pfam PF04402 Protein of unknown function (DUF541) 3 179 1.9E-24 T 12-10-2018 IPR007497 Protein of unknown function DUF541 TL08_26760 b4d7884765552b50723c50ee478fc994 188 Gene3D G3DSA:3.30.70.2970 4 93 1.2E-17 T 12-10-2018 TL08_26760 b4d7884765552b50723c50ee478fc994 188 Gene3D G3DSA:3.30.110.170 94 161 1.2E-17 T 12-10-2018 TL08_24240 49d1e889fb55e55454e2917502cbf914 117 Pfam PF14534 Domain of unknown function (DUF4440) 13 106 3.5E-15 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 TL08_24240 49d1e889fb55e55454e2917502cbf914 117 Gene3D G3DSA:3.10.450.50 3 115 1.1E-12 T 12-10-2018 TL08_24240 49d1e889fb55e55454e2917502cbf914 117 SUPERFAMILY SSF54427 5 116 3.83E-17 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_21715 9c98a621a3f5ef9995b5e80d688cbe23 415 SUPERFAMILY SSF53756 41 413 1.88E-78 T 12-10-2018 TL08_21715 9c98a621a3f5ef9995b5e80d688cbe23 415 Gene3D G3DSA:3.40.50.2000 42 403 2.7E-126 T 12-10-2018 TL08_21715 9c98a621a3f5ef9995b5e80d688cbe23 415 Gene3D G3DSA:3.40.50.2000 209 402 2.7E-126 T 12-10-2018 TL08_21715 9c98a621a3f5ef9995b5e80d688cbe23 415 Pfam PF13439 Glycosyltransferase Family 4 52 211 7.4E-12 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_21715 9c98a621a3f5ef9995b5e80d688cbe23 415 Pfam PF00534 Glycosyl transferases group 1 222 395 4.3E-41 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 1.3E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 1.3E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 1.3E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 123 1.3E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 67 77 1.3E-19 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 SUPERFAMILY SSF51905 4 311 2.09E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 Hamap MF_01685 Ferredoxin--NADP reductase. 8 328 37.755 T 12-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 4.2E-16 T 12-10-2018 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 4.2E-16 T 12-10-2018 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 4.2E-16 T 12-10-2018 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 Gene3D G3DSA:3.50.50.60 130 246 9.7E-89 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 293 5.9E-31 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TL08_04155 67cd9733e9e4d49ff43dd63f340c10d0 328 Gene3D G3DSA:3.50.50.60 10 307 9.7E-89 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06270 6faadb4e41bd65b0bb2e2cf53549172a 407 Pfam PF04261 Dyp-type peroxidase family 66 396 9.0E-73 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 TL08_06270 6faadb4e41bd65b0bb2e2cf53549172a 407 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 66 396 3.6E-66 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 TL08_06270 6faadb4e41bd65b0bb2e2cf53549172a 407 SUPERFAMILY SSF54909 61 401 6.79E-79 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_01920 6fbd47aaefa39f015ab2c157aeeee193 375 Gene3D G3DSA:3.40.50.1980 42 255 5.4E-32 T 12-10-2018 TL08_01920 6fbd47aaefa39f015ab2c157aeeee193 375 Gene3D G3DSA:3.40.50.2300 293 363 5.0E-6 T 12-10-2018 TL08_01920 6fbd47aaefa39f015ab2c157aeeee193 375 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 370 6.8E-51 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TL08_01920 6fbd47aaefa39f015ab2c157aeeee193 375 SUPERFAMILY SSF53807 20 373 3.41E-58 T 12-10-2018 TL08_01670 7d9160030605625c14c477bd4bfa110c 209 SUPERFAMILY SSF55620 20 207 8.89E-78 T 12-10-2018 TL08_01670 7d9160030605625c14c477bd4bfa110c 209 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 30 207 4.9E-71 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TL08_01670 7d9160030605625c14c477bd4bfa110c 209 Pfam PF01227 GTP cyclohydrolase I 29 206 1.3E-75 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TL08_01670 7d9160030605625c14c477bd4bfa110c 209 Gene3D G3DSA:1.10.286.10 11 72 6.7E-19 T 12-10-2018 TL08_01670 7d9160030605625c14c477bd4bfa110c 209 Gene3D G3DSA:3.30.1130.10 74 209 3.7E-60 T 12-10-2018 TL08_01670 7d9160030605625c14c477bd4bfa110c 209 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 134 144 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TL08_01670 7d9160030605625c14c477bd4bfa110c 209 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 24 207 42.105 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TL08_22475 eef0430a0cbf28f2850a88062207acf0 293 SUPERFAMILY SSF103481 41 143 4.71E-11 T 12-10-2018 TL08_22475 eef0430a0cbf28f2850a88062207acf0 293 Pfam PF00892 EamA-like transporter family 6 140 4.8E-24 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_22475 eef0430a0cbf28f2850a88062207acf0 293 Pfam PF00892 EamA-like transporter family 151 285 6.3E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_22475 eef0430a0cbf28f2850a88062207acf0 293 SUPERFAMILY SSF103481 189 288 1.01E-11 T 12-10-2018 TL08_25860 8d4f68f4f7cc2a542817926256284b71 308 SUPERFAMILY SSF55073 119 283 1.73E-38 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_25860 8d4f68f4f7cc2a542817926256284b71 308 Gene3D G3DSA:3.30.70.270 100 283 2.9E-46 T 12-10-2018 TL08_25860 8d4f68f4f7cc2a542817926256284b71 308 SMART SM00267 103 282 9.8E-42 T 12-10-2018 IPR000160 GGDEF domain TL08_25860 8d4f68f4f7cc2a542817926256284b71 308 Pfam PF00990 Diguanylate cyclase, GGDEF domain 115 277 9.6E-32 T 12-10-2018 IPR000160 GGDEF domain TL08_25860 8d4f68f4f7cc2a542817926256284b71 308 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 111 282 3.1E-39 T 12-10-2018 IPR000160 GGDEF domain TL08_25870 91bc76858de813d53b1872f351c9d040 667 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 521 604 4.4E-16 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain TL08_25870 91bc76858de813d53b1872f351c9d040 667 Gene3D G3DSA:3.30.70.2390 520 598 4.9E-8 T 12-10-2018 TL08_25870 91bc76858de813d53b1872f351c9d040 667 Gene3D G3DSA:1.10.260.150 186 481 1.2E-60 T 12-10-2018 TL08_25870 91bc76858de813d53b1872f351c9d040 667 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 235 399 2.4E-37 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TL08_25870 91bc76858de813d53b1872f351c9d040 667 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 234 399 1.1E-44 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TL08_21550 8d63ef8415097e4c9407082219ed9c1e 294 Gene3D G3DSA:3.20.20.220 2 294 2.0E-95 T 12-10-2018 TL08_21550 8d63ef8415097e4c9407082219ed9c1e 294 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 15 287 2.5E-90 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 TL08_21550 8d63ef8415097e4c9407082219ed9c1e 294 SUPERFAMILY SSF51730 2 290 5.89E-92 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like TL08_21550 8d63ef8415097e4c9407082219ed9c1e 294 Pfam PF02219 Methylenetetrahydrofolate reductase 6 288 4.2E-91 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TL08_08550 34dff54c11fb152ca8d8956871b49c25 232 SUPERFAMILY SSF53213 95 222 3.79E-6 T 12-10-2018 TL08_08550 34dff54c11fb152ca8d8956871b49c25 232 Gene3D G3DSA:3.40.830.10 74 222 2.2E-23 T 12-10-2018 TL08_20065 4d0a0605256f4b478a6b216712a5c1b4 544 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 4 498 1.8E-100 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 TL08_20065 4d0a0605256f4b478a6b216712a5c1b4 544 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 4 516 1.9E-53 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 TL08_19235 43e7690ec3f1c1f5a137c4d1aed8c36d 63 Pfam PF04149 Domain of unknown function (DUF397) 7 58 2.6E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_06230 9b3e07eb43b7450481fa443a26c07480 376 Gene3D G3DSA:3.40.50.720 187 321 1.2E-66 T 12-10-2018 TL08_06230 9b3e07eb43b7450481fa443a26c07480 376 Pfam PF00107 Zinc-binding dehydrogenase 213 334 1.8E-16 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_06230 9b3e07eb43b7450481fa443a26c07480 376 Gene3D G3DSA:3.90.180.10 46 365 1.2E-66 T 12-10-2018 TL08_06230 9b3e07eb43b7450481fa443a26c07480 376 SUPERFAMILY SSF51735 174 336 2.25E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_06230 9b3e07eb43b7450481fa443a26c07480 376 TIGRFAM TIGR03366 HpnZ_proposed: putative phosphonate catabolism associated alcohol dehydrogenase 47 354 6.3E-127 T 12-10-2018 IPR017743 Alcohol dehydrogenase, phosphonate catabolism-associated, putative TL08_06230 9b3e07eb43b7450481fa443a26c07480 376 SUPERFAMILY SSF50129 26 372 6.45E-29 T 12-10-2018 IPR011032 GroES-like superfamily TL08_06230 9b3e07eb43b7450481fa443a26c07480 376 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 49 163 4.9E-20 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_14430 a878e183a13432b7527a3b2a8d680326 377 Gene3D G3DSA:3.40.50.720 1 173 2.4E-19 T 12-10-2018 TL08_14430 a878e183a13432b7527a3b2a8d680326 377 Pfam PF13460 NAD(P)H-binding 6 122 5.7E-11 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_14430 a878e183a13432b7527a3b2a8d680326 377 SUPERFAMILY SSF51735 1 99 9.09E-16 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_27120 44065b38a750a77d386da40b290cb417 300 Pfam PF13614 AAA domain 40 217 1.8E-57 T 12-10-2018 IPR025669 AAA domain TL08_27120 44065b38a750a77d386da40b290cb417 300 Gene3D G3DSA:3.40.50.300 37 296 1.2E-76 T 12-10-2018 TL08_27120 44065b38a750a77d386da40b290cb417 300 SUPERFAMILY SSF52540 40 291 6.08E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17030 7a58728b6b2b1370639c64145151f23d 241 Pfam PF06912 Protein of unknown function (DUF1275) 16 223 8.7E-36 T 12-10-2018 IPR010699 Protein of unknown function DUF1275 TL08_03215 e2060042c7c729e78a45a27d8b4cafea 232 Gene3D G3DSA:3.40.50.2300 1 128 3.2E-41 T 12-10-2018 TL08_03215 e2060042c7c729e78a45a27d8b4cafea 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 6.7E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_03215 e2060042c7c729e78a45a27d8b4cafea 232 SMART SM00862 152 227 2.3E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_03215 e2060042c7c729e78a45a27d8b4cafea 232 SMART SM00448 1 112 1.0E-45 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_03215 e2060042c7c729e78a45a27d8b4cafea 232 SUPERFAMILY SSF46894 132 228 5.95E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_03215 e2060042c7c729e78a45a27d8b4cafea 232 SUPERFAMILY SSF52172 1 122 3.13E-44 T 12-10-2018 IPR011006 CheY-like superfamily TL08_03215 e2060042c7c729e78a45a27d8b4cafea 232 Pfam PF00072 Response regulator receiver domain 3 112 4.8E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_03215 e2060042c7c729e78a45a27d8b4cafea 232 Gene3D G3DSA:1.10.10.10 132 231 2.5E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_19875 4fc02a3e86791d206881c84b154fc368 509 SUPERFAMILY SSF103473 9 503 2.22E-61 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_19875 4fc02a3e86791d206881c84b154fc368 509 Pfam PF07690 Major Facilitator Superfamily 24 411 7.5E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_19875 4fc02a3e86791d206881c84b154fc368 509 Gene3D G3DSA:1.20.1720.10 16 248 6.6E-44 T 12-10-2018 TL08_19875 4fc02a3e86791d206881c84b154fc368 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 402 421 7.7E-7 T 12-10-2018 TL08_19875 4fc02a3e86791d206881c84b154fc368 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 78 100 7.7E-7 T 12-10-2018 TL08_19875 4fc02a3e86791d206881c84b154fc368 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 165 189 7.7E-7 T 12-10-2018 TL08_19875 4fc02a3e86791d206881c84b154fc368 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 7.7E-7 T 12-10-2018 TL08_19875 4fc02a3e86791d206881c84b154fc368 509 Gene3D G3DSA:1.20.1250.20 269 501 4.7E-11 T 12-10-2018 TL08_11485 c3ca027305a5c7ae675b7dd3c3f31db4 451 Gene3D G3DSA:3.20.20.140 62 389 1.1E-122 T 12-10-2018 TL08_11485 c3ca027305a5c7ae675b7dd3c3f31db4 451 Pfam PF01979 Amidohydrolase family 57 441 2.2E-21 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_11485 c3ca027305a5c7ae675b7dd3c3f31db4 451 Hamap MF_00220_B Dihydroorotase [pyrC]. 11 446 40.679 T 12-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11485 c3ca027305a5c7ae675b7dd3c3f31db4 451 SUPERFAMILY SSF51556 61 388 3.11E-91 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_11485 c3ca027305a5c7ae675b7dd3c3f31db4 451 Gene3D G3DSA:2.30.40.10 20 441 1.1E-122 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_11485 c3ca027305a5c7ae675b7dd3c3f31db4 451 ProSitePatterns PS00483 Dihydroorotase signature 2. 323 334 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TL08_11485 c3ca027305a5c7ae675b7dd3c3f31db4 451 SUPERFAMILY SSF51338 21 450 9.84E-22 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TL08_11485 c3ca027305a5c7ae675b7dd3c3f31db4 451 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 23 446 7.9E-130 T 12-10-2018 TL08_13990 eca44b11c472a8d7f98031a3fb077a99 545 Gene3D G3DSA:1.20.1560.10 1 292 1.8E-42 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_13990 eca44b11c472a8d7f98031a3fb077a99 545 SUPERFAMILY SSF90123 2 296 1.57E-47 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_13990 eca44b11c472a8d7f98031a3fb077a99 545 Pfam PF00005 ABC transporter 349 453 3.3E-8 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_13990 eca44b11c472a8d7f98031a3fb077a99 545 SUPERFAMILY SSF52540 337 521 1.22E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13990 eca44b11c472a8d7f98031a3fb077a99 545 Pfam PF00664 ABC transporter transmembrane region 5 259 7.2E-24 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_13990 eca44b11c472a8d7f98031a3fb077a99 545 Gene3D G3DSA:3.40.50.300 313 532 7.9E-44 T 12-10-2018 TL08_13990 eca44b11c472a8d7f98031a3fb077a99 545 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_13040 823471a40419413c3415da13d415eca5 289 SMART SM00701 1 137 1.6E-13 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_13040 823471a40419413c3415da13d415eca5 289 SUPERFAMILY SSF55846 2 158 5.23E-36 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_13040 823471a40419413c3415da13d415eca5 289 Gene3D G3DSA:3.40.80.10 1 165 8.6E-38 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_13040 823471a40419413c3415da13d415eca5 289 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 24 145 4.1E-17 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_13040 823471a40419413c3415da13d415eca5 289 SMART SM00644 14 145 2.6E-7 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 TL08_22335 43f706fb4fb5c7d5d775dce6fea56f57 116 SUPERFAMILY SSF55797 1 115 6.02E-24 T 12-10-2018 IPR035940 CAP superfamily TL08_22335 43f706fb4fb5c7d5d775dce6fea56f57 116 Pfam PF00188 Cysteine-rich secretory protein family 3 114 4.1E-21 T 12-10-2018 IPR014044 CAP domain TL08_22335 43f706fb4fb5c7d5d775dce6fea56f57 116 Gene3D G3DSA:3.40.33.10 1 115 2.9E-47 T 12-10-2018 IPR035940 CAP superfamily TL08_07400 0dbe6110bbb674167e39d88125a8ed5a 197 SUPERFAMILY SSF55811 14 185 5.01E-36 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_07400 0dbe6110bbb674167e39d88125a8ed5a 197 Gene3D G3DSA:3.90.79.10 11 196 2.9E-42 T 12-10-2018 TL08_07400 0dbe6110bbb674167e39d88125a8ed5a 197 Pfam PF00293 NUDIX domain 53 166 4.0E-10 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_05550 4fa288c67aa1990bc6bc95c96c88dfe9 437 Gene3D G3DSA:3.90.1150.10 31 425 9.6E-132 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_05550 4fa288c67aa1990bc6bc95c96c88dfe9 437 SUPERFAMILY SSF53383 18 432 1.27E-109 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_05550 4fa288c67aa1990bc6bc95c96c88dfe9 437 Pfam PF00202 Aminotransferase class-III 26 430 5.4E-85 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_05550 4fa288c67aa1990bc6bc95c96c88dfe9 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_05550 4fa288c67aa1990bc6bc95c96c88dfe9 437 Gene3D G3DSA:3.40.640.10 60 324 9.6E-132 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_02830 6e0c6467fed3dfeafc82c8e0ba5dff22 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 25.334 T 12-10-2018 IPR007551 Protein of unknown function DUF520 TL08_02830 6e0c6467fed3dfeafc82c8e0ba5dff22 163 SUPERFAMILY SSF89963 5 87 5.49E-26 T 12-10-2018 IPR036183 YajQ-like superfamily TL08_02830 6e0c6467fed3dfeafc82c8e0ba5dff22 163 SUPERFAMILY SSF89963 92 163 6.02E-25 T 12-10-2018 IPR036183 YajQ-like superfamily TL08_02830 6e0c6467fed3dfeafc82c8e0ba5dff22 163 Gene3D G3DSA:3.30.70.860 5 163 2.2E-60 T 12-10-2018 IPR035571 UPF0234-like, C-terminal TL08_02830 6e0c6467fed3dfeafc82c8e0ba5dff22 163 Gene3D G3DSA:3.30.70.990 11 100 2.2E-60 T 12-10-2018 IPR035570 UPF0234, N-terminal TL08_02830 6e0c6467fed3dfeafc82c8e0ba5dff22 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 3.0E-61 T 12-10-2018 IPR007551 Protein of unknown function DUF520 TL08_17220 af7bd091c4a92179312a9b7673834d32 365 Gene3D G3DSA:1.20.1530.20 17 352 7.9E-26 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TL08_17220 af7bd091c4a92179312a9b7673834d32 365 PIRSF PIRSF005508 3 361 3.5E-136 T 12-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TL08_17220 af7bd091c4a92179312a9b7673834d32 365 Pfam PF01758 Sodium Bile acid symporter family 64 258 3.3E-63 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TL08_17220 af7bd091c4a92179312a9b7673834d32 365 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 17 345 1.3E-131 T 12-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TL08_24610 ba1ecdcfd0ec2c0f7d80d3fcc36b7b47 229 SUPERFAMILY SSF51261 90 222 8.89E-48 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_24610 ba1ecdcfd0ec2c0f7d80d3fcc36b7b47 229 Pfam PF01551 Peptidase family M23 122 218 4.5E-31 T 12-10-2018 IPR016047 Peptidase M23 TL08_24610 ba1ecdcfd0ec2c0f7d80d3fcc36b7b47 229 Gene3D G3DSA:2.70.70.10 68 225 1.2E-44 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_26055 d1d7a048d0fed4cda78add55e751c865 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 19.412 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_26055 d1d7a048d0fed4cda78add55e751c865 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 75 9.4E-15 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_26055 d1d7a048d0fed4cda78add55e751c865 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 5.9E-25 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_26055 d1d7a048d0fed4cda78add55e751c865 79 Gene3D G3DSA:3.30.1280.10 2 79 4.8E-25 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_26055 d1d7a048d0fed4cda78add55e751c865 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 74 8.0E-22 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TL08_26055 d1d7a048d0fed4cda78add55e751c865 79 SUPERFAMILY SSF82697 3 77 2.27E-22 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TL08_14190 14cdcbb067a1abd67c65cf6c3e0d7ac2 197 SUPERFAMILY SSF46689 17 87 2.26E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_14190 14cdcbb067a1abd67c65cf6c3e0d7ac2 197 SUPERFAMILY SSF48498 89 192 3.45E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_14190 14cdcbb067a1abd67c65cf6c3e0d7ac2 197 Gene3D G3DSA:1.10.357.10 2 196 2.5E-50 T 12-10-2018 TL08_14190 14cdcbb067a1abd67c65cf6c3e0d7ac2 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 7.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14190 14cdcbb067a1abd67c65cf6c3e0d7ac2 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 7.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_14190 14cdcbb067a1abd67c65cf6c3e0d7ac2 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 6.0E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_23400 ff3a0e239f4d2cb1735bdfdcd9f0ad46 303 Gene3D G3DSA:3.90.550.10 15 259 3.4E-31 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_23400 ff3a0e239f4d2cb1735bdfdcd9f0ad46 303 Pfam PF00535 Glycosyl transferase family 2 24 204 9.3E-15 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_23400 ff3a0e239f4d2cb1735bdfdcd9f0ad46 303 SUPERFAMILY SSF53448 22 269 2.18E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00705 b98647e8d63f959c18e22c82eff61fb1 670 SUPERFAMILY SSF53448 238 462 1.03E-21 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00705 b98647e8d63f959c18e22c82eff61fb1 670 Gene3D G3DSA:3.90.550.60 51 443 1.6E-133 T 12-10-2018 TL08_00705 b98647e8d63f959c18e22c82eff61fb1 670 Pfam PF13641 Glycosyltransferase like family 2 206 459 3.6E-36 T 12-10-2018 TL08_27090 07ecca0b00742007d7770f1591395825 109 PIRSF PIRSF000077 2 108 1.3E-44 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TL08_27090 07ecca0b00742007d7770f1591395825 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 1.2E-40 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TL08_27090 07ecca0b00742007d7770f1591395825 109 SUPERFAMILY SSF52833 5 109 2.79E-40 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_27090 07ecca0b00742007d7770f1591395825 109 Pfam PF00085 Thioredoxin 6 107 6.2E-36 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 TL08_27090 07ecca0b00742007d7770f1591395825 109 PRINTS PR00421 Thioredoxin family signature 32 41 5.7E-9 T 12-10-2018 TL08_27090 07ecca0b00742007d7770f1591395825 109 PRINTS PR00421 Thioredoxin family signature 24 32 5.7E-9 T 12-10-2018 TL08_27090 07ecca0b00742007d7770f1591395825 109 PRINTS PR00421 Thioredoxin family signature 72 83 5.7E-9 T 12-10-2018 TL08_27090 07ecca0b00742007d7770f1591395825 109 Gene3D G3DSA:3.40.30.10 2 109 4.6E-39 T 12-10-2018 TL08_27090 07ecca0b00742007d7770f1591395825 109 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TL08_10165 3d5a378e6bd072e5cdeae07be829de56 171 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 29 144 7.9E-6 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TL08_26655 173fe4c78707dae8902371357d75fe21 612 Pfam PF00350 Dynamin family 49 202 1.6E-12 T 12-10-2018 IPR022812 Dynamin superfamily TL08_26655 173fe4c78707dae8902371357d75fe21 612 Gene3D G3DSA:3.40.50.300 49 276 2.3E-25 T 12-10-2018 TL08_26655 173fe4c78707dae8902371357d75fe21 612 SUPERFAMILY SSF52540 42 278 8.11E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17010 6bbe8407b806771966f166e61e5f1fa8 135 Gene3D G3DSA:3.30.720.110 70 122 1.8E-18 T 12-10-2018 TL08_17010 6bbe8407b806771966f166e61e5f1fa8 135 Gene3D G3DSA:3.30.720.120 3 51 9.2E-6 T 12-10-2018 TL08_17010 6bbe8407b806771966f166e61e5f1fa8 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 120 6.3E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_17010 6bbe8407b806771966f166e61e5f1fa8 135 SUPERFAMILY SSF54593 6 122 1.61E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_16690 dc6f09190f723ed1f55b7b58f6385e87 283 Pfam PF00106 short chain dehydrogenase 7 148 4.6E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_16690 dc6f09190f723ed1f55b7b58f6385e87 283 Gene3D G3DSA:3.40.50.720 1 277 1.9E-33 T 12-10-2018 TL08_16690 dc6f09190f723ed1f55b7b58f6385e87 283 SUPERFAMILY SSF51735 4 268 3.75E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_10030 84f244b42cc4c19cd98302ed9f40d75a 229 Pfam PF01872 RibD C-terminal domain 5 215 5.6E-40 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TL08_10030 84f244b42cc4c19cd98302ed9f40d75a 229 Gene3D G3DSA:3.40.430.10 1 228 1.9E-55 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_10030 84f244b42cc4c19cd98302ed9f40d75a 229 SUPERFAMILY SSF53597 3 222 8.9E-46 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 Gene3D G3DSA:2.60.40.420 391 607 3.3E-53 T 12-10-2018 IPR008972 Cupredoxin TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 Gene3D G3DSA:2.60.40.420 212 389 8.0E-57 T 12-10-2018 IPR008972 Cupredoxin TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 ProSitePatterns PS00079 Multicopper oxidases signature 1. 562 582 - T 12-10-2018 IPR033138 Multicopper oxidases, conserved site TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 ProSitePatterns PS00080 Multicopper oxidases signature 2. 567 578 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 Gene3D G3DSA:2.60.40.420 26 211 1.3E-55 T 12-10-2018 IPR008972 Cupredoxin TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 Pfam PF07732 Multicopper oxidase 145 214 6.8E-6 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 Pfam PF07732 Multicopper oxidase 72 106 1.2E-5 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 Pfam PF07731 Multicopper oxidase 467 587 3.1E-21 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 SUPERFAMILY SSF49503 33 215 7.96E-24 T 12-10-2018 IPR008972 Cupredoxin TL08_10825 d88c0a15481606cb621f50d1f37711a8 614 SUPERFAMILY SSF49503 218 591 2.26E-30 T 12-10-2018 IPR008972 Cupredoxin TL08_10620 22910985e14696df2fc27aa5cac6cace 434 Pfam PF07690 Major Facilitator Superfamily 237 399 3.3E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_10620 22910985e14696df2fc27aa5cac6cace 434 Gene3D G3DSA:1.20.1250.20 8 196 5.4E-10 T 12-10-2018 TL08_10620 22910985e14696df2fc27aa5cac6cace 434 Gene3D G3DSA:1.20.1250.20 208 396 7.2E-11 T 12-10-2018 TL08_10620 22910985e14696df2fc27aa5cac6cace 434 SUPERFAMILY SSF103473 14 389 3.14E-27 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_20945 05d413c761f04aa32bf99b637de0c575 285 Gene3D G3DSA:3.90.25.10 131 267 3.1E-56 T 12-10-2018 TL08_20945 05d413c761f04aa32bf99b637de0c575 285 Gene3D G3DSA:3.40.50.720 10 265 3.1E-56 T 12-10-2018 TL08_20945 05d413c761f04aa32bf99b637de0c575 285 SUPERFAMILY SSF51735 8 275 3.27E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_20945 05d413c761f04aa32bf99b637de0c575 285 Pfam PF13460 NAD(P)H-binding 13 107 6.4E-17 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 SUPERFAMILY SSF52172 1 128 1.38E-34 T 12-10-2018 IPR011006 CheY-like superfamily TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 Pfam PF00072 Response regulator receiver domain 4 118 1.0E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 SMART SM00448 2 117 1.4E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 SMART SM00421 152 209 2.8E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 Gene3D G3DSA:3.40.50.12740 2 215 4.0E-71 T 12-10-2018 TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.1E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_20200 cca2c8312d580ffff5da85927b6def2f 221 SUPERFAMILY SSF46894 144 215 4.76E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_02060 b4e0f5e8645fb1b32641e39f54390484 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.5E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_02060 b4e0f5e8645fb1b32641e39f54390484 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.5E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_02060 b4e0f5e8645fb1b32641e39f54390484 203 SUPERFAMILY SSF46689 4 76 2.1E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_02060 b4e0f5e8645fb1b32641e39f54390484 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.8E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_02060 b4e0f5e8645fb1b32641e39f54390484 203 Gene3D G3DSA:1.10.357.10 3 196 1.9E-35 T 12-10-2018 TL08_19745 5db5a63643c288baaad2cf741277509f 349 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 272 285 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TL08_19745 5db5a63643c288baaad2cf741277509f 349 SUPERFAMILY SSF53613 6 325 6.39E-62 T 12-10-2018 IPR029056 Ribokinase-like TL08_19745 5db5a63643c288baaad2cf741277509f 349 Pfam PF00294 pfkB family carbohydrate kinase 8 313 3.1E-43 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_19745 5db5a63643c288baaad2cf741277509f 349 Gene3D G3DSA:3.40.1190.20 6 331 3.0E-76 T 12-10-2018 IPR029056 Ribokinase-like TL08_22390 fc675b197296830d9884af55553ee858 60 SUPERFAMILY SSF57829 2 57 1.71E-19 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TL08_22390 fc675b197296830d9884af55553ee858 60 Pfam PF01783 Ribosomal L32p protein family 2 57 1.1E-26 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_22390 fc675b197296830d9884af55553ee858 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 57 18.77 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_22390 fc675b197296830d9884af55553ee858 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 1.6E-24 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_26620 ae0f303343c78ca72b501081fd23bbfe 379 Pfam PF04230 Polysaccharide pyruvyl transferase 20 321 9.0E-19 T 12-10-2018 IPR007345 Polysaccharide pyruvyl transferase TL08_00940 374000eae1afb0342558b5920395ddf4 313 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TL08_00940 374000eae1afb0342558b5920395ddf4 313 Gene3D G3DSA:3.40.50.720 103 279 3.7E-91 T 12-10-2018 TL08_00940 374000eae1afb0342558b5920395ddf4 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 281 1.1E-46 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TL08_00940 374000eae1afb0342558b5920395ddf4 313 Gene3D G3DSA:3.40.50.720 37 305 3.7E-91 T 12-10-2018 TL08_00940 374000eae1afb0342558b5920395ddf4 313 SUPERFAMILY SSF52283 12 137 3.97E-33 T 12-10-2018 TL08_00940 374000eae1afb0342558b5920395ddf4 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 310 1.4E-28 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TL08_00940 374000eae1afb0342558b5920395ddf4 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TL08_00940 374000eae1afb0342558b5920395ddf4 313 SUPERFAMILY SSF51735 103 282 6.54E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_03785 b2d87562b68094b453d3b2a076263650 537 SUPERFAMILY SSF53955 142 307 3.66E-36 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_03785 b2d87562b68094b453d3b2a076263650 537 Pfam PF13406 Transglycosylase SLT domain 225 272 5.1E-8 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 TL08_19595 00e67c4987e7ad173026086a1d464d3e 316 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 155 273 2.5E-30 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TL08_19595 00e67c4987e7ad173026086a1d464d3e 316 Gene3D G3DSA:3.40.50.2000 145 312 3.9E-42 T 12-10-2018 TL08_19595 00e67c4987e7ad173026086a1d464d3e 316 SUPERFAMILY SSF53756 6 310 2.83E-59 T 12-10-2018 TL08_19595 00e67c4987e7ad173026086a1d464d3e 316 Gene3D G3DSA:3.40.50.2000 6 92 2.8E-9 T 12-10-2018 TL08_05730 c77c19c346acef5454f9d11b88be6e0d 261 Gene3D G3DSA:3.40.50.1820 5 254 2.3E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05730 c77c19c346acef5454f9d11b88be6e0d 261 Pfam PF12697 Alpha/beta hydrolase family 25 246 9.6E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05730 c77c19c346acef5454f9d11b88be6e0d 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 1.1E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05730 c77c19c346acef5454f9d11b88be6e0d 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 1.1E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05730 c77c19c346acef5454f9d11b88be6e0d 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 1.1E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05730 c77c19c346acef5454f9d11b88be6e0d 261 SUPERFAMILY SSF53474 14 254 9.18E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_23830 b796d3800345919f1b868dcae619cdac 298 SUPERFAMILY SSF51658 59 296 1.2E-38 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_23830 b796d3800345919f1b868dcae619cdac 298 Pfam PF01261 Xylose isomerase-like TIM barrel 80 254 1.1E-18 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_23830 b796d3800345919f1b868dcae619cdac 298 Gene3D G3DSA:3.20.20.150 40 298 9.8E-65 T 12-10-2018 TL08_15435 eeaef5ad354cf7e157245ad687f974a9 346 SUPERFAMILY SSF103481 225 296 5.36E-10 T 12-10-2018 TL08_15435 eeaef5ad354cf7e157245ad687f974a9 346 Pfam PF00892 EamA-like transporter family 153 294 4.3E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_15435 eeaef5ad354cf7e157245ad687f974a9 346 Pfam PF00892 EamA-like transporter family 11 142 9.6E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_15435 eeaef5ad354cf7e157245ad687f974a9 346 SUPERFAMILY SSF103481 46 142 1.96E-12 T 12-10-2018 TL08_05940 155f950dbcdccbaf661cc9a7c6f25c35 336 Gene3D G3DSA:3.20.20.70 12 262 4.1E-20 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_05940 155f950dbcdccbaf661cc9a7c6f25c35 336 SUPERFAMILY SSF102114 20 234 1.1E-22 T 12-10-2018 TL08_05940 155f950dbcdccbaf661cc9a7c6f25c35 336 Pfam PF04055 Radical SAM superfamily 23 145 5.3E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TL08_20815 055922dc3925f3cde04cebd05bb2723c 605 Gene3D G3DSA:3.30.420.10 2 167 8.5E-40 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TL08_20815 055922dc3925f3cde04cebd05bb2723c 605 SMART SM00292 517 595 0.0037 T 12-10-2018 IPR001357 BRCT domain TL08_20815 055922dc3925f3cde04cebd05bb2723c 605 SUPERFAMILY SSF52113 520 593 7.19E-7 T 12-10-2018 IPR036420 BRCT domain superfamily TL08_20815 055922dc3925f3cde04cebd05bb2723c 605 Pfam PF00929 Exonuclease 7 160 7.9E-19 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_20815 055922dc3925f3cde04cebd05bb2723c 605 SUPERFAMILY SSF53098 4 169 8.86E-43 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TL08_20815 055922dc3925f3cde04cebd05bb2723c 605 SMART SM00479 4 170 8.7E-25 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TL08_20815 055922dc3925f3cde04cebd05bb2723c 605 Gene3D G3DSA:3.40.50.10190 518 599 1.8E-13 T 12-10-2018 IPR036420 BRCT domain superfamily TL08_16290 6f04249c81f55b74602f786be6c8c93a 420 Pfam PF00155 Aminotransferase class I and II 79 395 4.3E-35 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TL08_16290 6f04249c81f55b74602f786be6c8c93a 420 Gene3D G3DSA:3.40.640.10 85 308 1.7E-92 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_16290 6f04249c81f55b74602f786be6c8c93a 420 SUPERFAMILY SSF53383 40 414 2.58E-85 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_16290 6f04249c81f55b74602f786be6c8c93a 420 Gene3D G3DSA:3.90.1150.10 48 413 1.7E-92 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_23415 aea7d1154206e666741dc733b48fe065 331 Pfam PF00535 Glycosyl transferase family 2 10 184 3.7E-19 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_23415 aea7d1154206e666741dc733b48fe065 331 Gene3D G3DSA:3.90.550.10 2 231 3.0E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_23415 aea7d1154206e666741dc733b48fe065 331 SUPERFAMILY SSF53448 5 250 6.75E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_08805 f38cd4ff0ebb5cb1cc9a28ffd7fd45ec 549 SUPERFAMILY SSF53850 45 524 1.69E-102 T 12-10-2018 TL08_08805 f38cd4ff0ebb5cb1cc9a28ffd7fd45ec 549 Gene3D G3DSA:3.40.190.10 49 533 2.7E-154 T 12-10-2018 TL08_08805 f38cd4ff0ebb5cb1cc9a28ffd7fd45ec 549 Gene3D G3DSA:3.90.76.10 67 172 2.7E-154 T 12-10-2018 TL08_08805 f38cd4ff0ebb5cb1cc9a28ffd7fd45ec 549 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 435 3.6E-71 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_08805 f38cd4ff0ebb5cb1cc9a28ffd7fd45ec 549 PIRSF PIRSF002741 2 528 2.3E-84 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_08805 f38cd4ff0ebb5cb1cc9a28ffd7fd45ec 549 Gene3D G3DSA:3.10.105.10 271 509 2.7E-154 T 12-10-2018 TL08_12185 3c80ae829722e59222ca19ce68df7b54 209 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 92 175 1.6E-8 T 12-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF TL08_12185 3c80ae829722e59222ca19ce68df7b54 209 Pfam PF08044 Domain of unknown function (DUF1707) 11 63 2.2E-22 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_09500 a644ab212629768c4668007883d828ed 338 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 330 3.2E-82 T 12-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related TL08_09500 a644ab212629768c4668007883d828ed 338 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 2 330 3.4E-141 T 12-10-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase TL08_09500 a644ab212629768c4668007883d828ed 338 SUPERFAMILY SSF51679 1 330 1.83E-76 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_09500 a644ab212629768c4668007883d828ed 338 Pfam PF00296 Luciferase-like monooxygenase 9 304 9.1E-62 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_09500 a644ab212629768c4668007883d828ed 338 Gene3D G3DSA:3.20.20.30 1 333 3.4E-98 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_25305 4697cbf25c8e29d13c52a920c2d050ed 203 SUPERFAMILY SSF52540 21 194 5.33E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25305 4697cbf25c8e29d13c52a920c2d050ed 203 Pfam PF03029 Conserved hypothetical ATP binding protein 26 194 7.3E-27 T 12-10-2018 IPR004130 GPN-loop GTPase TL08_25305 4697cbf25c8e29d13c52a920c2d050ed 203 Gene3D G3DSA:3.40.50.300 14 198 5.8E-18 T 12-10-2018 TL08_14395 c57c931febaec8fb8d3747ab7a486a71 1259 Gene3D G3DSA:3.40.50.300 952 1133 1.6E-40 T 12-10-2018 TL08_14395 c57c931febaec8fb8d3747ab7a486a71 1259 Pfam PF00656 Caspase domain 8 243 2.9E-12 T 12-10-2018 TL08_14395 c57c931febaec8fb8d3747ab7a486a71 1259 Gene3D G3DSA:3.40.50.1460 2 187 2.6E-17 T 12-10-2018 TL08_14395 c57c931febaec8fb8d3747ab7a486a71 1259 Pfam PF13086 AAA domain 554 721 1.5E-10 T 12-10-2018 TL08_14395 c57c931febaec8fb8d3747ab7a486a71 1259 Pfam PF13086 AAA domain 847 898 1.5E-7 T 12-10-2018 TL08_14395 c57c931febaec8fb8d3747ab7a486a71 1259 Pfam PF13087 AAA domain 933 1113 2.4E-31 T 12-10-2018 TL08_14395 c57c931febaec8fb8d3747ab7a486a71 1259 SUPERFAMILY SSF52540 552 1115 3.33E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_04405 6c43501bb245e3d48c820866417454af 270 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 1.7E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_04405 6c43501bb245e3d48c820866417454af 270 Gene3D G3DSA:1.10.10.10 136 234 7.6E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04405 6c43501bb245e3d48c820866417454af 270 SUPERFAMILY SSF52172 8 186 4.27E-37 T 12-10-2018 IPR011006 CheY-like superfamily TL08_04405 6c43501bb245e3d48c820866417454af 270 SMART SM00862 153 228 3.2E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TL08_04405 6c43501bb245e3d48c820866417454af 270 SMART SM00448 8 119 5.9E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_04405 6c43501bb245e3d48c820866417454af 270 Pfam PF00072 Response regulator receiver domain 10 118 2.9E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_04405 6c43501bb245e3d48c820866417454af 270 Gene3D G3DSA:3.40.50.2300 6 135 3.7E-34 T 12-10-2018 TL08_17815 70c22cbfe40481b931e1367f5816c5ee 712 SUPERFAMILY SSF53955 62 273 2.22E-61 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_17815 70c22cbfe40481b931e1367f5816c5ee 712 Gene3D G3DSA:1.10.3810.10 63 275 3.0E-67 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_17815 70c22cbfe40481b931e1367f5816c5ee 712 Gene3D G3DSA:3.40.710.10 307 710 6.2E-72 T 12-10-2018 TL08_17815 70c22cbfe40481b931e1367f5816c5ee 712 Pfam PF00905 Penicillin binding protein transpeptidase domain 376 647 1.6E-22 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TL08_17815 70c22cbfe40481b931e1367f5816c5ee 712 Pfam PF00912 Transglycosylase 71 260 3.1E-58 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_17815 70c22cbfe40481b931e1367f5816c5ee 712 SUPERFAMILY SSF56601 242 710 1.13E-75 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_26690 8e1006725ba413ea3b200d0c0461e221 87 Pfam PF11755 Protein of unknown function (DUF3311) 20 73 2.0E-12 T 12-10-2018 IPR021741 Protein of unknown function DUF3311 TL08_24135 f6e2f6013acff3de50565d71f7d568a6 345 Pfam PF00296 Luciferase-like monooxygenase 10 305 9.2E-63 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_24135 f6e2f6013acff3de50565d71f7d568a6 345 Gene3D G3DSA:3.20.20.30 4 335 1.3E-69 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_24135 f6e2f6013acff3de50565d71f7d568a6 345 TIGRFAM TIGR03617 F420_MSMEG_2256: probable F420-dependent oxidoreductase, MSMEG_2256 family 19 335 2.0E-129 T 12-10-2018 IPR019919 Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted TL08_24135 f6e2f6013acff3de50565d71f7d568a6 345 SUPERFAMILY SSF51679 8 333 6.18E-59 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_08810 c79db9b70a4afec1190ce9f9610612eb 329 Gene3D G3DSA:1.10.3720.10 93 322 1.8E-16 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08810 c79db9b70a4afec1190ce9f9610612eb 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 327 3.2E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_08810 c79db9b70a4afec1190ce9f9610612eb 329 SUPERFAMILY SSF161098 99 309 1.37E-13 T 12-10-2018 IPR035906 MetI-like superfamily TL08_11390 99c0dfbdf20eb0435466837e8219878f 461 Pfam PF02378 Phosphotransferase system, EIIC 25 336 1.0E-70 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TL08_08175 1dc43e5c6701ba12b714ceb6e89a99ed 505 SUPERFAMILY SSF48452 316 431 1.63E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_08175 1dc43e5c6701ba12b714ceb6e89a99ed 505 Gene3D G3DSA:1.25.40.10 298 491 3.8E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_02575 110e195cd1a9ecfe39393ea6de08ddc4 174 Pfam PF01883 Iron-sulfur cluster assembly protein 7 70 9.6E-15 T 12-10-2018 IPR002744 MIP18 family-like TL08_02575 110e195cd1a9ecfe39393ea6de08ddc4 174 Gene3D G3DSA:3.30.300.130 4 101 1.4E-21 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TL08_02575 110e195cd1a9ecfe39393ea6de08ddc4 174 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 16 174 1.5E-50 T 12-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit TL08_02575 110e195cd1a9ecfe39393ea6de08ddc4 174 SUPERFAMILY SSF117916 4 98 6.54E-22 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 Gene3D G3DSA:2.40.50.140 295 378 2.9E-29 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 SUPERFAMILY SSF50249 218 300 1.58E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 Gene3D G3DSA:2.40.50.140 33 128 1.3E-22 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 Gene3D G3DSA:2.40.50.140 129 210 6.8E-9 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 SUPERFAMILY SSF50249 39 141 8.21E-22 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 SUPERFAMILY SSF50249 288 376 5.28E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 SMART SM00316 218 288 3.2E-28 T 12-10-2018 IPR022967 RNA-binding domain, S1 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 SMART SM00316 45 116 1.6E-16 T 12-10-2018 IPR022967 RNA-binding domain, S1 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 SMART SM00316 132 199 2.0E-9 T 12-10-2018 IPR022967 RNA-binding domain, S1 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 SMART SM00316 303 374 4.6E-25 T 12-10-2018 IPR022967 RNA-binding domain, S1 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 Pfam PF00575 S1 RNA binding domain 44 116 8.1E-15 T 12-10-2018 IPR003029 S1 domain GO:0003676 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 Pfam PF00575 S1 RNA binding domain 132 199 2.1E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 Pfam PF00575 S1 RNA binding domain 217 288 4.5E-26 T 12-10-2018 IPR003029 S1 domain GO:0003676 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 Pfam PF00575 S1 RNA binding domain 302 374 5.9E-24 T 12-10-2018 IPR003029 S1 domain GO:0003676 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 Gene3D G3DSA:2.40.50.140 215 294 1.4E-30 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 PRINTS PR00681 Ribosomal protein S1 signature 240 261 3.5E-87 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 PRINTS PR00681 Ribosomal protein S1 signature 357 375 3.5E-87 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 PRINTS PR00681 Ribosomal protein S1 signature 137 153 3.5E-87 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 PRINTS PR00681 Ribosomal protein S1 signature 318 337 3.5E-87 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 PRINTS PR00681 Ribosomal protein S1 signature 183 203 3.5E-87 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 PRINTS PR00681 Ribosomal protein S1 signature 47 65 3.5E-87 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 PRINTS PR00681 Ribosomal protein S1 signature 65 79 3.5E-87 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 PRINTS PR00681 Ribosomal protein S1 signature 113 132 3.5E-87 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 PRINTS PR00681 Ribosomal protein S1 signature 154 171 3.5E-87 T 12-10-2018 TL08_10250 2be1fb60e7c0b9b245b8e9aa2e45b242 497 SUPERFAMILY SSF50249 118 202 5.86E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_23145 bad714283c1da028c43d0a55044b403a 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 13 198 6.4E-48 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_23145 bad714283c1da028c43d0a55044b403a 200 Gene3D G3DSA:3.40.50.1240 4 199 3.0E-55 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_23145 bad714283c1da028c43d0a55044b403a 200 SUPERFAMILY SSF53254 12 192 5.24E-50 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TL08_23145 bad714283c1da028c43d0a55044b403a 200 SMART SM00855 12 160 1.1E-21 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TL08_23145 bad714283c1da028c43d0a55044b403a 200 PIRSF PIRSF000709 7 175 1.4E-12 T 12-10-2018 TL08_08745 6858d3b3f91eefaa1982165a66d6a4d2 367 SUPERFAMILY SSF51556 48 326 6.81E-60 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_08745 6858d3b3f91eefaa1982165a66d6a4d2 367 Pfam PF01979 Amidohydrolase family 166 342 5.1E-9 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TL08_08745 6858d3b3f91eefaa1982165a66d6a4d2 367 Gene3D G3DSA:3.20.20.140 50 325 1.4E-50 T 12-10-2018 TL08_01945 4766651a8f50207317986389229294a2 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 296 3.8E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_01945 4766651a8f50207317986389229294a2 305 Gene3D G3DSA:1.10.3720.10 59 303 3.2E-68 T 12-10-2018 IPR035906 MetI-like superfamily TL08_01945 4766651a8f50207317986389229294a2 305 SUPERFAMILY SSF161098 62 290 3.79E-58 T 12-10-2018 IPR035906 MetI-like superfamily TL08_00025 a8c082a642fa8ce4bed4bb0e295a134e 203 Pfam PF05258 Protein of unknown function (DUF721) 91 178 4.8E-24 T 12-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 TL08_00025 a8c082a642fa8ce4bed4bb0e295a134e 203 Hamap MF_00630 UPF0232 protein . 9 190 29.824 T 12-10-2018 IPR023007 Uncharacterised protein family UPF0232, actinobacteria TL08_20215 42ee4efa8614dca5f2cb43c73996f644 581 SUPERFAMILY SSF52540 347 566 4.7E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20215 42ee4efa8614dca5f2cb43c73996f644 581 Pfam PF00664 ABC transporter transmembrane region 56 253 1.4E-13 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_20215 42ee4efa8614dca5f2cb43c73996f644 581 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_20215 42ee4efa8614dca5f2cb43c73996f644 581 Gene3D G3DSA:3.40.50.300 344 578 7.0E-72 T 12-10-2018 TL08_20215 42ee4efa8614dca5f2cb43c73996f644 581 Pfam PF00005 ABC transporter 366 517 1.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_20215 42ee4efa8614dca5f2cb43c73996f644 581 Gene3D G3DSA:1.20.1560.10 11 301 1.2E-29 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_20215 42ee4efa8614dca5f2cb43c73996f644 581 SUPERFAMILY SSF90123 12 301 2.75E-36 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_20215 42ee4efa8614dca5f2cb43c73996f644 581 SMART SM00382 375 563 2.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_20215 42ee4efa8614dca5f2cb43c73996f644 581 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 14 559 3.2E-163 T 12-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 TL08_12380 4d0c8efeccec636986a81f1ef7d8d401 123 Pfam PF13564 DoxX-like family 7 110 8.5E-22 T 12-10-2018 IPR032808 DoxX family TL08_03235 73aa30e52a668c2d486884aaa4b93370 216 Pfam PF00994 Probable molybdopterin binding domain 63 204 1.6E-25 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_03235 73aa30e52a668c2d486884aaa4b93370 216 Gene3D G3DSA:3.40.980.10 56 214 3.1E-45 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TL08_03235 73aa30e52a668c2d486884aaa4b93370 216 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 60 199 5.1E-27 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_03235 73aa30e52a668c2d486884aaa4b93370 216 SUPERFAMILY SSF53218 60 209 2.88E-34 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TL08_03235 73aa30e52a668c2d486884aaa4b93370 216 SMART SM00852 62 206 2.6E-17 T 12-10-2018 IPR001453 MoaB/Mog domain TL08_24225 9212ba991d44c080383032abc6287a7f 89 Pfam PF04149 Domain of unknown function (DUF397) 32 81 3.6E-13 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_20350 5814173ab44050b9b6a54958bccf30b2 316 Pfam PF00294 pfkB family carbohydrate kinase 24 288 1.2E-28 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_20350 5814173ab44050b9b6a54958bccf30b2 316 SUPERFAMILY SSF53613 27 302 8.11E-38 T 12-10-2018 IPR029056 Ribokinase-like TL08_20350 5814173ab44050b9b6a54958bccf30b2 316 PIRSF PIRSF000535 8 306 1.7E-34 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TL08_20350 5814173ab44050b9b6a54958bccf30b2 316 Gene3D G3DSA:3.40.1190.20 7 311 2.7E-49 T 12-10-2018 IPR029056 Ribokinase-like TL08_11735 d98679bb44412238336c53a13c27569d 544 Pfam PF05960 Bacterial protein of unknown function (DUF885) 25 538 1.5E-104 T 12-10-2018 IPR010281 Protein of unknown function DUF885 TL08_18470 41848b971c024e3d23d438470985b382 328 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 18 296 2.0E-94 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TL08_18470 41848b971c024e3d23d438470985b382 328 Pfam PF02401 LytB protein 18 294 5.0E-86 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TL08_18470 41848b971c024e3d23d438470985b382 328 Gene3D G3DSA:3.40.1010.20 22 293 1.1E-106 T 12-10-2018 TL08_18470 41848b971c024e3d23d438470985b382 328 Gene3D G3DSA:3.40.50.11270 27 111 1.1E-106 T 12-10-2018 TL08_18470 41848b971c024e3d23d438470985b382 328 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 16 298 36.433 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TL08_18470 41848b971c024e3d23d438470985b382 328 Gene3D G3DSA:3.40.1010.20 112 208 1.1E-106 T 12-10-2018 TL08_19770 fbf45d0a06684d2a723c0d63412371f6 345 Pfam PF02126 Phosphotriesterase family 13 318 2.3E-90 T 12-10-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 TL08_19770 fbf45d0a06684d2a723c0d63412371f6 345 SUPERFAMILY SSF51556 3 319 1.84E-79 T 12-10-2018 IPR032466 Metal-dependent hydrolase TL08_19770 fbf45d0a06684d2a723c0d63412371f6 345 Gene3D G3DSA:3.20.20.140 3 319 6.3E-104 T 12-10-2018 TL08_19770 fbf45d0a06684d2a723c0d63412371f6 345 ProSitePatterns PS01322 Phosphotriesterase family signature 1. 17 25 - T 12-10-2018 IPR017947 Aryldialkylphosphatase, zinc-binding site GO:0008270|GO:0009056|GO:0016788 TL08_17705 cca4ec60bca9a6cb41a03c7b81035308 277 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 1 277 48.856 T 12-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 TL08_17705 cca4ec60bca9a6cb41a03c7b81035308 277 SUPERFAMILY SSF51182 1 261 3.09E-91 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_17705 cca4ec60bca9a6cb41a03c7b81035308 277 Pfam PF04962 KduI/IolB family 62 271 4.5E-30 T 12-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 TL08_17705 cca4ec60bca9a6cb41a03c7b81035308 277 Gene3D G3DSA:2.60.120.10 10 262 2.5E-110 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_17705 cca4ec60bca9a6cb41a03c7b81035308 277 PIRSF PIRSF006625 1 277 1.4E-112 T 12-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 TL08_17705 cca4ec60bca9a6cb41a03c7b81035308 277 Gene3D G3DSA:2.60.120.520 30 143 2.5E-110 T 12-10-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 SUPERFAMILY SSF52172 1 138 3.27E-19 T 12-10-2018 IPR011006 CheY-like superfamily TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 SUPERFAMILY SSF46894 136 195 3.2E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 SMART SM00421 147 210 6.5E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 Gene3D G3DSA:3.40.50.12740 1 202 5.1E-45 T 12-10-2018 TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 Pfam PF00072 Response regulator receiver domain 3 108 1.9E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 195 9.9E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_02165 382695c2020284c7fe151f2587fc8aaa 226 SMART SM00448 1 120 1.5E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_01280 03e99c9f1465223992d45975ccbf6a18 423 Gene3D G3DSA:1.20.1250.20 223 414 4.0E-10 T 12-10-2018 TL08_01280 03e99c9f1465223992d45975ccbf6a18 423 Gene3D G3DSA:1.20.1250.20 15 206 3.0E-13 T 12-10-2018 TL08_01280 03e99c9f1465223992d45975ccbf6a18 423 SUPERFAMILY SSF103473 29 402 6.15E-26 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_01280 03e99c9f1465223992d45975ccbf6a18 423 Pfam PF07690 Major Facilitator Superfamily 30 341 1.6E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_05240 c1077e2d6095e6130ea1df8c19a333cf 221 Gene3D G3DSA:3.40.50.850 10 204 5.0E-46 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TL08_05240 c1077e2d6095e6130ea1df8c19a333cf 221 Pfam PF00857 Isochorismatase family 18 168 1.1E-25 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 TL08_05240 c1077e2d6095e6130ea1df8c19a333cf 221 SUPERFAMILY SSF52499 11 197 1.83E-47 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TL08_14445 e32dff0586ebb8b392986eb36d8d6b13 547 SUPERFAMILY SSF56801 17 545 8.9E-139 T 12-10-2018 TL08_14445 e32dff0586ebb8b392986eb36d8d6b13 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 462 537 2.1E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TL08_14445 e32dff0586ebb8b392986eb36d8d6b13 547 Gene3D G3DSA:2.30.38.10 372 447 4.2E-27 T 12-10-2018 TL08_14445 e32dff0586ebb8b392986eb36d8d6b13 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 205 216 - T 12-10-2018 IPR020845 AMP-binding, conserved site TL08_14445 e32dff0586ebb8b392986eb36d8d6b13 547 Pfam PF00501 AMP-binding enzyme 45 453 5.0E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TL08_14445 e32dff0586ebb8b392986eb36d8d6b13 547 Gene3D G3DSA:3.40.50.980 199 371 8.2E-55 T 12-10-2018 TL08_14445 e32dff0586ebb8b392986eb36d8d6b13 547 Gene3D G3DSA:3.30.300.30 448 547 2.1E-28 T 12-10-2018 TL08_14445 e32dff0586ebb8b392986eb36d8d6b13 547 Gene3D G3DSA:3.40.50.980 33 191 2.6E-48 T 12-10-2018 TL08_26685 482cece052856a51f7191c0796c5568d 302 Pfam PF13845 Septum formation 75 280 3.0E-37 T 12-10-2018 IPR026004 Septum formation-related domain TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 Pfam PF01470 Pyroglutamyl peptidase 4 203 4.5E-66 T 12-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 219 4.7E-73 T 12-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 6.5E-38 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 6.5E-38 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 6.5E-38 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 6.5E-38 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 SUPERFAMILY SSF53182 1 217 1.1E-64 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 PIRSF PIRSF015592 1 214 2.4E-72 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 205 37.1 T 12-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TL08_09945 3bcc9691182a2f28501011c5de72ffa9 219 Gene3D G3DSA:3.40.630.20 2 219 5.8E-74 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TL08_21745 228fea039f13f0e5ff71b77dfe742a20 561 SUPERFAMILY SSF81342 23 300 9.58E-62 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TL08_21745 228fea039f13f0e5ff71b77dfe742a20 561 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 124 297 9.7E-61 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TL08_21745 228fea039f13f0e5ff71b77dfe742a20 561 Gene3D G3DSA:1.20.810.10 14 438 3.5E-93 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 TL08_07410 eec005e9ee882fe996f0306a1d996633 227 Pfam PF01939 Endonuclease NucS 8 227 4.1E-82 T 12-10-2018 IPR002793 Endonuclease NucS GO:0004519 TL08_07410 eec005e9ee882fe996f0306a1d996633 227 Gene3D G3DSA:2.70.180.20 4 97 7.8E-20 T 12-10-2018 TL08_07410 eec005e9ee882fe996f0306a1d996633 227 Gene3D G3DSA:3.40.1350.10 102 213 6.6E-25 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TL08_07410 eec005e9ee882fe996f0306a1d996633 227 Hamap MF_00722 Endonuclease NucS [nucS]. 9 219 31.279 T 12-10-2018 IPR002793 Endonuclease NucS GO:0004519 TL08_25190 961c2d0bdabccd32aee5ff2bdb3d63e3 536 SUPERFAMILY SSF103473 50 441 2.22E-49 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_25190 961c2d0bdabccd32aee5ff2bdb3d63e3 536 Gene3D G3DSA:1.20.1250.20 48 436 2.2E-48 T 12-10-2018 TL08_25190 961c2d0bdabccd32aee5ff2bdb3d63e3 536 Pfam PF05977 Transmembrane secretion effector 43 437 1.9E-56 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_23915 1ac01779b7b49bd8d23e6b04c7d5e476 384 Gene3D G3DSA:3.40.50.150 8 245 5.4E-47 T 12-10-2018 TL08_23915 1ac01779b7b49bd8d23e6b04c7d5e476 384 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 166 181 - T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TL08_23915 1ac01779b7b49bd8d23e6b04c7d5e476 384 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 14 209 1.7E-26 T 12-10-2018 TL08_23915 1ac01779b7b49bd8d23e6b04c7d5e476 384 SUPERFAMILY SSF53335 7 208 6.92E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_26795 30eb98ff345f166bf81105731c2849ff 362 Pfam PF01658 Myo-inositol-1-phosphate synthase 194 302 2.1E-31 T 12-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TL08_26795 30eb98ff345f166bf81105731c2849ff 362 PIRSF PIRSF015578 2 358 6.1E-94 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TL08_26795 30eb98ff345f166bf81105731c2849ff 362 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 7 356 3.3E-207 T 12-10-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria TL08_26795 30eb98ff345f166bf81105731c2849ff 362 Gene3D G3DSA:3.40.50.720 7 355 6.0E-149 T 12-10-2018 TL08_26795 30eb98ff345f166bf81105731c2849ff 362 SUPERFAMILY SSF51735 6 358 1.18E-93 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_26795 30eb98ff345f166bf81105731c2849ff 362 SUPERFAMILY SSF55347 193 301 1.57E-34 T 12-10-2018 TL08_26795 30eb98ff345f166bf81105731c2849ff 362 Gene3D G3DSA:3.30.360.10 193 302 6.0E-149 T 12-10-2018 TL08_12050 00efd25742cb211a30b2735f28d89c87 328 SUPERFAMILY SSF51430 53 314 4.06E-36 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_12050 00efd25742cb211a30b2735f28d89c87 328 Gene3D G3DSA:3.20.20.100 16 302 1.9E-37 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_12050 00efd25742cb211a30b2735f28d89c87 328 Pfam PF00248 Aldo/keto reductase family 58 311 8.9E-21 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_13335 32929ac7fb79e3caf248a0f500c80f54 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.6E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_13335 32929ac7fb79e3caf248a0f500c80f54 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.6E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_13335 32929ac7fb79e3caf248a0f500c80f54 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.6E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_13335 32929ac7fb79e3caf248a0f500c80f54 110 Pfam PF12840 Helix-turn-helix domain 11 68 1.4E-13 T 12-10-2018 TL08_13335 32929ac7fb79e3caf248a0f500c80f54 110 SMART SM00418 11 89 2.6E-29 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TL08_13335 32929ac7fb79e3caf248a0f500c80f54 110 SUPERFAMILY SSF46785 10 103 1.11E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_13335 32929ac7fb79e3caf248a0f500c80f54 110 Gene3D G3DSA:1.10.10.10 3 98 2.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_22855 d15ce1231eef880c594d9519487c762c 469 SUPERFAMILY SSF56176 352 431 1.06E-19 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_22855 d15ce1231eef880c594d9519487c762c 469 Gene3D G3DSA:3.30.465.10 355 426 6.7E-20 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TL08_22855 d15ce1231eef880c594d9519487c762c 469 SMART SM00116 222 271 0.011 T 12-10-2018 IPR000644 CBS domain TL08_22855 d15ce1231eef880c594d9519487c762c 469 SMART SM00116 285 333 14.0 T 12-10-2018 IPR000644 CBS domain TL08_22855 d15ce1231eef880c594d9519487c762c 469 Gene3D G3DSA:3.10.580.10 194 347 9.9E-47 T 12-10-2018 TL08_22855 d15ce1231eef880c594d9519487c762c 469 SUPERFAMILY SSF54631 210 343 6.06E-29 T 12-10-2018 TL08_22855 d15ce1231eef880c594d9519487c762c 469 SMART SM01091 348 426 2.7E-21 T 12-10-2018 IPR005170 Transporter-associated domain TL08_22855 d15ce1231eef880c594d9519487c762c 469 Pfam PF03471 Transporter associated domain 351 424 3.2E-22 T 12-10-2018 IPR005170 Transporter-associated domain TL08_22855 d15ce1231eef880c594d9519487c762c 469 Pfam PF01595 Domain of unknown function DUF21 10 193 8.8E-42 T 12-10-2018 IPR002550 CNNM, transmembrane domain TL08_22855 d15ce1231eef880c594d9519487c762c 469 Pfam PF00571 CBS domain 298 333 4.7E-4 T 12-10-2018 IPR000644 CBS domain TL08_22855 d15ce1231eef880c594d9519487c762c 469 Pfam PF00571 CBS domain 218 270 2.2E-6 T 12-10-2018 IPR000644 CBS domain TL08_06545 de539cf2d6be1ce58a2b64560c4f2b45 159 PIRSF PIRSF000239 2 156 2.3E-20 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TL08_06545 de539cf2d6be1ce58a2b64560c4f2b45 159 Pfam PF00578 AhpC/TSA family 10 137 9.5E-37 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TL08_06545 de539cf2d6be1ce58a2b64560c4f2b45 159 SUPERFAMILY SSF52833 6 156 9.13E-48 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_06545 de539cf2d6be1ce58a2b64560c4f2b45 159 Gene3D G3DSA:3.40.30.10 8 157 6.8E-48 T 12-10-2018 TL08_21470 d136836f9c6ac8c4a1311287bf4c1a53 116 Gene3D G3DSA:3.30.370.10 20 107 2.2E-8 T 12-10-2018 IPR035905 Barstar-like superfamily TL08_21470 d136836f9c6ac8c4a1311287bf4c1a53 116 SUPERFAMILY SSF52038 22 102 1.18E-14 T 12-10-2018 IPR035905 Barstar-like superfamily TL08_21470 d136836f9c6ac8c4a1311287bf4c1a53 116 Pfam PF01337 Barstar (barnase inhibitor) 23 102 1.2E-14 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) TL08_16990 0660801f98f0f6fe70bfdab15eaa3564 408 Gene3D G3DSA:1.20.1250.20 18 392 2.3E-29 T 12-10-2018 TL08_16990 0660801f98f0f6fe70bfdab15eaa3564 408 ProSitePatterns PS00216 Sugar transport proteins signature 1. 74 90 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_16990 0660801f98f0f6fe70bfdab15eaa3564 408 Pfam PF07690 Major Facilitator Superfamily 26 353 6.1E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_16990 0660801f98f0f6fe70bfdab15eaa3564 408 SUPERFAMILY SSF103473 23 393 3.27E-33 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_20515 3aaae0d0f1991024d37137c78183f41b 120 Pfam PF03334 Na+/H+ antiporter subunit 12 91 7.5E-20 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TL08_20515 3aaae0d0f1991024d37137c78183f41b 120 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 105 1.1E-18 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TL08_03690 d6d0b67d837479291fcae28ecc400c21 404 Pfam PF01566 Natural resistance-associated macrophage protein 14 374 1.1E-27 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TL08_00115 29a979bf10c63cf8496c89910d426f6c 134 Pfam PF12680 SnoaL-like domain 14 113 2.1E-10 T 12-10-2018 IPR037401 SnoaL-like domain TL08_00115 29a979bf10c63cf8496c89910d426f6c 134 Gene3D G3DSA:3.10.450.50 4 130 1.1E-23 T 12-10-2018 TL08_00115 29a979bf10c63cf8496c89910d426f6c 134 SUPERFAMILY SSF54427 7 123 6.05E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_15185 7b908b9f803e64b2148ee3b4297a2c8b 717 SUPERFAMILY SSF49785 568 691 5.76E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_15185 7b908b9f803e64b2148ee3b4297a2c8b 717 SUPERFAMILY SSF48208 109 514 2.31E-30 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_15185 7b908b9f803e64b2148ee3b4297a2c8b 717 Gene3D G3DSA:2.60.120.260 556 703 3.5E-24 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TL08_15185 7b908b9f803e64b2148ee3b4297a2c8b 717 Pfam PF00754 F5/8 type C domain 570 691 1.9E-10 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain TL08_15185 7b908b9f803e64b2148ee3b4297a2c8b 717 Gene3D G3DSA:1.50.10.10 89 456 2.9E-18 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_01480 114f54a45af396898cf70a9b9304640a 126 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 17 124 1.8E-25 T 12-10-2018 IPR021202 Apoptosis inhibitor Rv3654c-like TL08_01480 114f54a45af396898cf70a9b9304640a 126 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 19 65 5.0E-6 T 12-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal TL08_13305 1d1710efb7e3bddcbba778b0a5d5c982 262 SUPERFAMILY SSF46785 10 80 3.53E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_13305 1d1710efb7e3bddcbba778b0a5d5c982 262 Gene3D G3DSA:1.10.10.10 2 66 3.1E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_13305 1d1710efb7e3bddcbba778b0a5d5c982 262 SMART SM01134 79 240 2.0E-56 T 12-10-2018 TL08_13305 1d1710efb7e3bddcbba778b0a5d5c982 262 SUPERFAMILY SSF100950 83 239 9.0E-24 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_13305 1d1710efb7e3bddcbba778b0a5d5c982 262 SMART SM00420 12 64 2.0E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_13305 1d1710efb7e3bddcbba778b0a5d5c982 262 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TL08_13305 1d1710efb7e3bddcbba778b0a5d5c982 262 Pfam PF08220 DeoR-like helix-turn-helix domain 12 67 1.2E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TL08_13305 1d1710efb7e3bddcbba778b0a5d5c982 262 Pfam PF00455 DeoR C terminal sensor domain 83 238 1.2E-42 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain TL08_10330 83d2829e258aa26b3314615c89911f44 246 Gene3D G3DSA:3.40.50.10310 13 243 3.5E-59 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TL08_10330 83d2829e258aa26b3314615c89911f44 246 SUPERFAMILY SSF102215 4 241 1.11E-50 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TL08_10330 83d2829e258aa26b3314615c89911f44 246 Pfam PF02633 Creatinine amidohydrolase 19 237 2.9E-52 T 12-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TL08_19085 a6ab499efa8c65a073905666b8bea6f7 402 SUPERFAMILY SSF101898 59 336 4.45E-7 T 12-10-2018 TL08_12485 181a585bdfe7b451863a39542788f0a9 292 SUPERFAMILY SSF47413 14 80 4.44E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_12485 181a585bdfe7b451863a39542788f0a9 292 Pfam PF13560 Helix-turn-helix domain 16 82 1.4E-11 T 12-10-2018 TL08_12485 181a585bdfe7b451863a39542788f0a9 292 Gene3D G3DSA:1.10.260.40 13 81 2.6E-7 T 12-10-2018 TL08_12485 181a585bdfe7b451863a39542788f0a9 292 SMART SM00530 20 79 0.0038 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_09755 1f2cc8fbcb52389f078d490806a07dde 118 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 62 113 5.0E-19 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TL08_09755 1f2cc8fbcb52389f078d490806a07dde 118 Gene3D G3DSA:3.10.20.400 5 100 7.8E-39 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TL08_09755 1f2cc8fbcb52389f078d490806a07dde 118 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 36 108 1.1E-33 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TL08_09755 1f2cc8fbcb52389f078d490806a07dde 118 SUPERFAMILY SSF141734 10 113 1.57E-45 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TL08_09755 1f2cc8fbcb52389f078d490806a07dde 118 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 10 113 31.252 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TL08_03645 397e0fe272a47a8432e8982bb5b65d6f 457 Gene3D G3DSA:1.20.1250.20 54 446 7.0E-39 T 12-10-2018 TL08_03645 397e0fe272a47a8432e8982bb5b65d6f 457 Pfam PF05977 Transmembrane secretion effector 52 439 3.0E-29 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_03645 397e0fe272a47a8432e8982bb5b65d6f 457 PRINTS PR01988 Putative bacilysin exporter bacE signature 300 317 5.2E-6 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TL08_03645 397e0fe272a47a8432e8982bb5b65d6f 457 PRINTS PR01988 Putative bacilysin exporter bacE signature 62 84 5.2E-6 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TL08_03645 397e0fe272a47a8432e8982bb5b65d6f 457 PRINTS PR01988 Putative bacilysin exporter bacE signature 125 143 5.2E-6 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TL08_03645 397e0fe272a47a8432e8982bb5b65d6f 457 PRINTS PR01988 Putative bacilysin exporter bacE signature 218 235 5.2E-6 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TL08_03645 397e0fe272a47a8432e8982bb5b65d6f 457 SUPERFAMILY SSF103473 57 443 8.63E-42 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_15150 9fe38af137e556dab47730c5c965bfdc 345 Pfam PF01965 DJ-1/PfpI family 25 196 1.8E-23 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TL08_15150 9fe38af137e556dab47730c5c965bfdc 345 SUPERFAMILY SSF46689 236 285 7.62E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_15150 9fe38af137e556dab47730c5c965bfdc 345 SUPERFAMILY SSF52317 23 216 1.31E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_15150 9fe38af137e556dab47730c5c965bfdc 345 SUPERFAMILY SSF46689 287 338 4.93E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_15150 9fe38af137e556dab47730c5c965bfdc 345 Gene3D G3DSA:3.40.50.880 20 224 8.3E-61 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TL08_15150 9fe38af137e556dab47730c5c965bfdc 345 Pfam PF12833 Helix-turn-helix domain 257 335 1.0E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_15150 9fe38af137e556dab47730c5c965bfdc 345 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 285 330 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TL08_15150 9fe38af137e556dab47730c5c965bfdc 345 SMART SM00342 251 334 3.5E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_15150 9fe38af137e556dab47730c5c965bfdc 345 Gene3D G3DSA:1.10.10.60 233 343 3.8E-24 T 12-10-2018 TL08_12560 d975b8516d03edfa0f84cad20ea3fded 381 Pfam PF01636 Phosphotransferase enzyme family 71 293 5.4E-45 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_12560 d975b8516d03edfa0f84cad20ea3fded 381 Gene3D G3DSA:3.30.200.20 46 149 4.6E-30 T 12-10-2018 TL08_12560 d975b8516d03edfa0f84cad20ea3fded 381 SUPERFAMILY SSF56112 45 352 1.94E-54 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_12560 d975b8516d03edfa0f84cad20ea3fded 381 Gene3D G3DSA:3.90.1200.10 154 378 1.5E-63 T 12-10-2018 TL08_26475 69e07ab28b8d532b296b990428055c0a 263 Pfam PF13649 Methyltransferase domain 44 141 1.6E-9 T 12-10-2018 TL08_26475 69e07ab28b8d532b296b990428055c0a 263 SUPERFAMILY SSF53335 32 246 2.03E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_10505 8101ee77dcd71b56298675bdae84c25c 273 SUPERFAMILY SSF53335 32 239 3.44E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_10505 8101ee77dcd71b56298675bdae84c25c 273 Gene3D G3DSA:3.40.50.150 33 248 6.8E-28 T 12-10-2018 TL08_10505 8101ee77dcd71b56298675bdae84c25c 273 Pfam PF13649 Methyltransferase domain 51 143 9.2E-9 T 12-10-2018 TL08_12820 d934206314fcea35c5291f2c2d7f9512 118 Pfam PF05331 Protein of unknown function (DUF742) 7 116 3.4E-30 T 12-10-2018 IPR007995 Protein of unknown function DUF742 TL08_09640 f708b543803dfc44b8666f112c11058c 202 Pfam PF00293 NUDIX domain 4 92 2.7E-6 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_09640 f708b543803dfc44b8666f112c11058c 202 Gene3D G3DSA:3.90.79.10 1 103 6.9E-22 T 12-10-2018 TL08_09640 f708b543803dfc44b8666f112c11058c 202 Gene3D G3DSA:1.10.10.10 106 189 9.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_09640 f708b543803dfc44b8666f112c11058c 202 SUPERFAMILY SSF55811 2 109 7.04E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_09640 f708b543803dfc44b8666f112c11058c 202 SUPERFAMILY SSF46785 113 184 1.06E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_24830 70aa6dfa11f0b67e54922ce9c59bea8b 229 Gene3D G3DSA:3.30.420.40 100 185 2.1E-39 T 12-10-2018 TL08_24830 70aa6dfa11f0b67e54922ce9c59bea8b 229 Pfam PF00814 Glycoprotease family 38 160 1.4E-26 T 12-10-2018 IPR000905 Gcp-like domain TL08_24830 70aa6dfa11f0b67e54922ce9c59bea8b 229 SUPERFAMILY SSF53067 3 107 3.58E-21 T 12-10-2018 TL08_24830 70aa6dfa11f0b67e54922ce9c59bea8b 229 SUPERFAMILY SSF53067 116 212 5.96E-7 T 12-10-2018 TL08_24830 70aa6dfa11f0b67e54922ce9c59bea8b 229 Gene3D G3DSA:3.30.420.40 3 214 2.1E-39 T 12-10-2018 TL08_24830 70aa6dfa11f0b67e54922ce9c59bea8b 229 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 214 1.1E-51 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 TL08_17615 0f0f3c3d1df83d142956da6c3b5d859d 179 SUPERFAMILY SSF48498 82 172 1.22E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_17615 0f0f3c3d1df83d142956da6c3b5d859d 179 SUPERFAMILY SSF46689 1 66 1.85E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_17615 0f0f3c3d1df83d142956da6c3b5d859d 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 3.8E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_17615 0f0f3c3d1df83d142956da6c3b5d859d 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_17615 0f0f3c3d1df83d142956da6c3b5d859d 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_17615 0f0f3c3d1df83d142956da6c3b5d859d 179 Gene3D G3DSA:1.10.357.10 1 178 3.2E-39 T 12-10-2018 TL08_13080 c316985380a5f2e73801d32b4dedbcb9 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 23 71 2.0E-6 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TL08_13080 c316985380a5f2e73801d32b4dedbcb9 300 SUPERFAMILY SSF161098 90 269 3.92E-25 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13080 c316985380a5f2e73801d32b4dedbcb9 300 Gene3D G3DSA:1.10.3720.10 84 297 3.0E-21 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13080 c316985380a5f2e73801d32b4dedbcb9 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 297 1.6E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_13455 7be7edd0d451788ad6e4cfef47115d2a 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 319 2.8E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_13455 7be7edd0d451788ad6e4cfef47115d2a 329 SUPERFAMILY SSF161098 90 316 9.68E-60 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13455 7be7edd0d451788ad6e4cfef47115d2a 329 Gene3D G3DSA:1.10.3720.10 85 326 2.6E-66 T 12-10-2018 IPR035906 MetI-like superfamily TL08_10595 9496ee5c7a6b6e201bdf3a3439ae3c66 432 Pfam PF00583 Acetyltransferase (GNAT) family 326 404 9.6E-7 T 12-10-2018 IPR000182 GNAT domain TL08_10595 9496ee5c7a6b6e201bdf3a3439ae3c66 432 SUPERFAMILY SSF55021 93 159 5.73E-6 T 12-10-2018 TL08_10595 9496ee5c7a6b6e201bdf3a3439ae3c66 432 SUPERFAMILY SSF55729 272 404 5.75E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_10595 9496ee5c7a6b6e201bdf3a3439ae3c66 432 Gene3D G3DSA:3.40.630.30 275 430 1.3E-22 T 12-10-2018 TL08_05635 6682fff4a6552ecf92b4086d709ce554 487 Pfam PF03559 NDP-hexose 2,3-dehydratase 29 230 7.5E-83 T 12-10-2018 IPR005212 NDP-hexose 2,3-dehydratase KEGG: 00523+4.2.1.159 TL08_05635 6682fff4a6552ecf92b4086d709ce554 487 Pfam PF03559 NDP-hexose 2,3-dehydratase 272 473 1.3E-75 T 12-10-2018 IPR005212 NDP-hexose 2,3-dehydratase KEGG: 00523+4.2.1.159 TL08_05635 6682fff4a6552ecf92b4086d709ce554 487 Gene3D G3DSA:3.90.79.40 325 483 1.1E-58 T 12-10-2018 IPR038153 NDP-hexose 2,3-dehydratase-like superfamily KEGG: 00523+4.2.1.159 TL08_05635 6682fff4a6552ecf92b4086d709ce554 487 Gene3D G3DSA:3.90.79.40 78 238 4.2E-61 T 12-10-2018 IPR038153 NDP-hexose 2,3-dehydratase-like superfamily KEGG: 00523+4.2.1.159 TL08_05620 dcfe5c07853c6e76414b7a34a2d1956d 339 SUPERFAMILY SSF53822 68 333 1.81E-58 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_05620 dcfe5c07853c6e76414b7a34a2d1956d 339 Gene3D G3DSA:1.10.260.40 1 61 1.4E-18 T 12-10-2018 TL08_05620 dcfe5c07853c6e76414b7a34a2d1956d 339 Pfam PF13377 Periplasmic binding protein-like domain 175 331 2.0E-35 T 12-10-2018 TL08_05620 dcfe5c07853c6e76414b7a34a2d1956d 339 Gene3D G3DSA:3.40.50.2300 62 310 8.3E-63 T 12-10-2018 TL08_05620 dcfe5c07853c6e76414b7a34a2d1956d 339 SUPERFAMILY SSF47413 9 66 1.03E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_05620 dcfe5c07853c6e76414b7a34a2d1956d 339 SMART SM00354 8 78 5.3E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_05620 dcfe5c07853c6e76414b7a34a2d1956d 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 1.6E-11 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TL08_05620 dcfe5c07853c6e76414b7a34a2d1956d 339 Gene3D G3DSA:3.40.50.2300 167 293 8.3E-63 T 12-10-2018 TL08_16230 b46beb51f543e7ef88a00c95c8eac8f9 222 Gene3D G3DSA:1.10.357.10 21 215 1.7E-32 T 12-10-2018 TL08_16230 b46beb51f543e7ef88a00c95c8eac8f9 222 SUPERFAMILY SSF46689 10 90 4.26E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16230 b46beb51f543e7ef88a00c95c8eac8f9 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 71 2.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_21620 5ebbaf15783469249e78c146f0c5c183 759 Pfam PF03639 Glycosyl hydrolase family 81 55 689 7.5E-66 T 12-10-2018 IPR005200 Endo-1,3(4)-beta-glucanase GO:0052861 TL08_09670 6856ad453480e5a0eabc4276436e4a83 233 Pfam PF01323 DSBA-like thioredoxin domain 21 221 7.2E-35 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 TL08_09670 6856ad453480e5a0eabc4276436e4a83 233 SUPERFAMILY SSF52833 19 226 7.09E-36 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_09670 6856ad453480e5a0eabc4276436e4a83 233 Gene3D G3DSA:3.40.30.10 11 225 1.4E-53 T 12-10-2018 TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 PRINTS PR00143 Citrate synthase signature 208 224 5.8E-5 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 PRINTS PR00143 Citrate synthase signature 228 242 5.8E-5 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 PRINTS PR00143 Citrate synthase signature 88 116 5.8E-5 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 PRINTS PR00143 Citrate synthase signature 149 169 5.8E-5 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 Gene3D G3DSA:1.10.580.10 65 248 3.1E-32 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 Gene3D G3DSA:1.10.580.10 15 62 1.8E-8 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 Gene3D G3DSA:1.10.230.10 114 222 3.1E-32 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 Pfam PF00285 Citrate synthase, C-terminal domain 60 254 4.0E-31 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 Pfam PF00285 Citrate synthase, C-terminal domain 19 61 2.2E-7 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TL08_25805 c6152343ce7162d3b7dab2822f3fdd55 288 SUPERFAMILY SSF48256 17 274 2.36E-54 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 TL08_05670 766baa4997e85d2da8b3baf42448448e 537 Gene3D G3DSA:3.30.9.50 73 287 3.8E-111 T 12-10-2018 TL08_05670 766baa4997e85d2da8b3baf42448448e 537 Pfam PF01494 FAD binding domain 5 355 3.5E-95 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_05670 766baa4997e85d2da8b3baf42448448e 537 Gene3D G3DSA:3.40.30.120 384 537 1.8E-44 T 12-10-2018 TL08_05670 766baa4997e85d2da8b3baf42448448e 537 SUPERFAMILY SSF51905 6 364 9.84E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05670 766baa4997e85d2da8b3baf42448448e 537 Gene3D G3DSA:3.50.50.60 7 349 3.8E-111 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05670 766baa4997e85d2da8b3baf42448448e 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 2.6E-44 T 12-10-2018 TL08_05670 766baa4997e85d2da8b3baf42448448e 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 162 177 2.6E-44 T 12-10-2018 TL08_05670 766baa4997e85d2da8b3baf42448448e 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.6E-44 T 12-10-2018 TL08_05670 766baa4997e85d2da8b3baf42448448e 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 2.6E-44 T 12-10-2018 TL08_05670 766baa4997e85d2da8b3baf42448448e 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 341 2.6E-44 T 12-10-2018 TL08_05670 766baa4997e85d2da8b3baf42448448e 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 357 2.6E-44 T 12-10-2018 TL08_16550 ae3224341ab34660ef1bb84b268986d6 284 Pfam PF00561 alpha/beta hydrolase fold 29 263 1.8E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16550 ae3224341ab34660ef1bb84b268986d6 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 220 234 2.0E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16550 ae3224341ab34660ef1bb84b268986d6 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 2.0E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16550 ae3224341ab34660ef1bb84b268986d6 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 2.0E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_16550 ae3224341ab34660ef1bb84b268986d6 284 SUPERFAMILY SSF53474 11 278 2.32E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16550 ae3224341ab34660ef1bb84b268986d6 284 Gene3D G3DSA:3.40.50.1820 9 280 1.7E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_11150 f5ca7c0c0c3ce061854b04ae81946f5e 60 SUPERFAMILY SSF47413 3 45 5.04E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_11150 f5ca7c0c0c3ce061854b04ae81946f5e 60 Pfam PF13560 Helix-turn-helix domain 2 46 2.5E-7 T 12-10-2018 TL08_11150 f5ca7c0c0c3ce061854b04ae81946f5e 60 Gene3D G3DSA:1.10.260.40 1 47 8.4E-21 T 12-10-2018 TL08_14470 3a72ce5d4f61f8ac8445f33ccff6a6c4 317 Gene3D G3DSA:1.10.3720.10 85 308 1.9E-13 T 12-10-2018 IPR035906 MetI-like superfamily TL08_14470 3a72ce5d4f61f8ac8445f33ccff6a6c4 317 SUPERFAMILY SSF161098 89 294 7.85E-13 T 12-10-2018 IPR035906 MetI-like superfamily TL08_14470 3a72ce5d4f61f8ac8445f33ccff6a6c4 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 309 8.5E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_08640 638f3871d753a592f7981c903de88e39 353 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 54 336 5.0E-89 T 12-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TL08_08640 638f3871d753a592f7981c903de88e39 353 Pfam PF03812 2-keto-3-deoxygluconate permease 33 336 2.0E-106 T 12-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TL08_12335 12b09925582572d95b02c4ad8b490828 599 Pfam PF09818 Predicted ATPase of the ABC class 35 455 1.6E-158 T 12-10-2018 IPR019195 ABC transporter, ATPase, putative TL08_12335 12b09925582572d95b02c4ad8b490828 599 SUPERFAMILY SSF52540 257 439 5.63E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12335 12b09925582572d95b02c4ad8b490828 599 Gene3D G3DSA:3.40.50.300 261 455 8.4E-6 T 12-10-2018 TL08_26720 ec487d8a722f3360f4753963efb92eb7 270 Gene3D G3DSA:3.40.50.300 17 260 1.6E-74 T 12-10-2018 TL08_26720 ec487d8a722f3360f4753963efb92eb7 270 Pfam PF00005 ABC transporter 35 183 1.3E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_26720 ec487d8a722f3360f4753963efb92eb7 270 PIRSF PIRSF039085 16 259 2.0E-111 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TL08_26720 ec487d8a722f3360f4753963efb92eb7 270 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_26720 ec487d8a722f3360f4753963efb92eb7 270 SUPERFAMILY SSF52540 19 253 1.66E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26720 ec487d8a722f3360f4753963efb92eb7 270 SMART SM00382 44 232 3.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_25875 f8e1a1161f6301bd5c93357b2c38b75a 219 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 2.6E-53 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TL08_25875 f8e1a1161f6301bd5c93357b2c38b75a 219 Pfam PF01895 PhoU domain 16 102 2.1E-15 T 12-10-2018 IPR026022 PhoU domain TL08_25875 f8e1a1161f6301bd5c93357b2c38b75a 219 Pfam PF01895 PhoU domain 123 203 6.4E-11 T 12-10-2018 IPR026022 PhoU domain TL08_25875 f8e1a1161f6301bd5c93357b2c38b75a 219 PIRSF PIRSF003107 1 218 2.0E-53 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TL08_25875 f8e1a1161f6301bd5c93357b2c38b75a 219 SUPERFAMILY SSF109755 2 214 5.86E-56 T 12-10-2018 TL08_25875 f8e1a1161f6301bd5c93357b2c38b75a 219 Gene3D G3DSA:1.20.58.220 1 216 1.3E-59 T 12-10-2018 IPR038078 PhoU-like domain superfamily TL08_18915 50d0eb6ce982b20c25eb58be13d29f3f 475 SUPERFAMILY SSF54001 79 171 2.13E-6 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TL08_18915 50d0eb6ce982b20c25eb58be13d29f3f 475 Gene3D G3DSA:3.90.1720.10 33 198 7.6E-10 T 12-10-2018 TL08_18915 50d0eb6ce982b20c25eb58be13d29f3f 475 SUPERFAMILY SSF89372 227 469 1.03E-13 T 12-10-2018 TL08_22555 733cde664c168eb6de5c4472bf8c297c 323 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 14 319 27.057 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TL08_22555 733cde664c168eb6de5c4472bf8c297c 323 SUPERFAMILY SSF56042 155 301 2.54E-31 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TL08_22555 733cde664c168eb6de5c4472bf8c297c 323 Gene3D G3DSA:3.30.1330.10 10 150 6.3E-44 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TL08_22555 733cde664c168eb6de5c4472bf8c297c 323 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 15 318 4.1E-84 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TL08_22555 733cde664c168eb6de5c4472bf8c297c 323 PIRSF PIRSF005303 9 319 8.9E-90 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TL08_22555 733cde664c168eb6de5c4472bf8c297c 323 SUPERFAMILY SSF55326 12 148 5.41E-34 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TL08_22555 733cde664c168eb6de5c4472bf8c297c 323 Pfam PF00586 AIR synthase related protein, N-terminal domain 39 148 2.3E-19 T 12-10-2018 IPR016188 PurM-like, N-terminal domain TL08_22555 733cde664c168eb6de5c4472bf8c297c 323 Gene3D G3DSA:3.90.650.10 157 319 1.4E-49 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TL08_23180 48b8ac192ca7e51ee9ba53bdea35ebfc 122 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 11 84 3.3E-28 T 12-10-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA TL08_23180 48b8ac192ca7e51ee9ba53bdea35ebfc 122 Pfam PF13490 Putative zinc-finger 11 44 1.0E-4 T 12-10-2018 IPR027383 Putative zinc-finger TL08_23180 48b8ac192ca7e51ee9ba53bdea35ebfc 122 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 5 82 2.6E-25 T 12-10-2018 IPR014295 Anti-sigma factor TL08_13885 7e4eb49dd0e2049dc417f728be771247 488 Gene3D G3DSA:3.30.465.10 115 481 6.9E-86 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TL08_13885 7e4eb49dd0e2049dc417f728be771247 488 Gene3D G3DSA:3.40.462.20 215 452 6.9E-86 T 12-10-2018 TL08_13885 7e4eb49dd0e2049dc417f728be771247 488 Pfam PF01565 FAD binding domain 51 183 1.6E-23 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TL08_13885 7e4eb49dd0e2049dc417f728be771247 488 Gene3D G3DSA:3.30.43.10 26 101 5.4E-13 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TL08_13885 7e4eb49dd0e2049dc417f728be771247 488 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 51 84 - T 12-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 TL08_13885 7e4eb49dd0e2049dc417f728be771247 488 SUPERFAMILY SSF56176 18 216 9.81E-43 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TL08_22115 5d871b87f0eeef7d97a486973423afe3 617 Pfam PF09660 Protein of unknown function (DUF2397) 86 573 9.0E-111 T 12-10-2018 IPR013493 Conserved hypothetical protein CHP02677 TL08_19575 64e1b1c137b6b9a5a42abb38604c37cd 351 Gene3D G3DSA:3.40.50.2000 1 155 2.0E-9 T 12-10-2018 TL08_19575 64e1b1c137b6b9a5a42abb38604c37cd 351 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 75 310 7.1E-23 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 TL08_19575 64e1b1c137b6b9a5a42abb38604c37cd 351 Gene3D G3DSA:3.40.50.2000 165 336 1.3E-35 T 12-10-2018 TL08_19575 64e1b1c137b6b9a5a42abb38604c37cd 351 SUPERFAMILY SSF53756 3 333 2.35E-63 T 12-10-2018 TL08_18820 738387aae4f40d71071ae92bff2fd994 470 SUPERFAMILY SSF103473 3 405 3.92E-32 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_18820 738387aae4f40d71071ae92bff2fd994 470 Pfam PF07690 Major Facilitator Superfamily 12 285 3.6E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_18820 738387aae4f40d71071ae92bff2fd994 470 Gene3D G3DSA:1.20.1250.20 2 405 2.6E-28 T 12-10-2018 TL08_19490 3e89a5b38091c1165a2028bd05b533dd 273 Pfam PF07920 Protein of unknown function (DUF1684) 125 265 3.9E-34 T 12-10-2018 IPR012467 Protein of unknown function DUF1684 TL08_01800 282ea855e89ae8f3fb19720d14a5659a 165 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 11 161 2.6E-47 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TL08_01800 282ea855e89ae8f3fb19720d14a5659a 165 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 10 162 30.763 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TL08_01800 282ea855e89ae8f3fb19720d14a5659a 165 Pfam PF02542 YgbB family 11 160 2.6E-47 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TL08_01800 282ea855e89ae8f3fb19720d14a5659a 165 Gene3D G3DSA:3.30.1330.50 6 164 3.8E-58 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TL08_01800 282ea855e89ae8f3fb19720d14a5659a 165 SUPERFAMILY SSF69765 10 162 2.09E-51 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TL08_01800 282ea855e89ae8f3fb19720d14a5659a 165 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 44 59 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TL08_09545 671d097d261bbb1d3a03eb9b3b5791b3 214 Pfam PF04472 Cell division protein SepF 128 199 1.9E-23 T 12-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 TL08_09545 671d097d261bbb1d3a03eb9b3b5791b3 214 Hamap MF_01197 Cell division protein SepF [sepF]. 1 207 21.435 T 12-10-2018 IPR023052 Cell division protein SepF GO:0090529 TL08_09545 671d097d261bbb1d3a03eb9b3b5791b3 214 Gene3D G3DSA:3.30.110.150 126 207 7.3E-26 T 12-10-2018 IPR038594 SepF-like superfamily TL08_21520 5f70cbf974a8804b26c608695814052e 260 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 24 139 3.3E-14 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 TL08_21520 5f70cbf974a8804b26c608695814052e 260 Pfam PF07398 MDMPI C-terminal domain 153 248 3.8E-8 T 12-10-2018 IPR010872 MDMPI C-terminal TL08_21520 5f70cbf974a8804b26c608695814052e 260 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 22 233 3.4E-17 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type TL08_21520 5f70cbf974a8804b26c608695814052e 260 SUPERFAMILY SSF109854 38 145 4.27E-6 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_12255 55f03ad521a77a512f659d81b4fb57f2 406 SUPERFAMILY SSF56059 114 315 1.88E-11 T 12-10-2018 TL08_27045 9408617b27893bff15f8d781abebcada 235 SUPERFAMILY SSF103647 118 188 9.94E-6 T 12-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TL08_27045 9408617b27893bff15f8d781abebcada 235 SUPERFAMILY SSF103647 41 99 1.29E-6 T 12-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TL08_12170 dc440826ee24928bf518343231a4cff9 183 Pfam PF04186 FxsA cytoplasmic membrane protein 5 108 1.5E-23 T 12-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 TL08_25110 3935d5019a2cafb08695c5576f767d6e 329 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 265 278 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TL08_25110 3935d5019a2cafb08695c5576f767d6e 329 Pfam PF00294 pfkB family carbohydrate kinase 26 323 1.8E-40 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TL08_25110 3935d5019a2cafb08695c5576f767d6e 329 SUPERFAMILY SSF53613 2 324 4.83E-62 T 12-10-2018 IPR029056 Ribokinase-like TL08_25110 3935d5019a2cafb08695c5576f767d6e 329 Gene3D G3DSA:3.40.1190.20 1 328 1.5E-72 T 12-10-2018 IPR029056 Ribokinase-like TL08_10655 325fe0481eaa944bdddf1320bc71c5a6 296 Pfam PF00950 ABC 3 transport family 16 273 2.2E-57 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TL08_10655 325fe0481eaa944bdddf1320bc71c5a6 296 SUPERFAMILY SSF81345 19 266 1.57E-23 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_00905 88a5fdbad4733c61db8bc95a846a80c1 311 Gene3D G3DSA:1.10.3720.10 85 297 1.5E-18 T 12-10-2018 IPR035906 MetI-like superfamily TL08_00905 88a5fdbad4733c61db8bc95a846a80c1 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 304 5.8E-34 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_00905 88a5fdbad4733c61db8bc95a846a80c1 311 SUPERFAMILY SSF161098 91 292 4.25E-15 T 12-10-2018 IPR035906 MetI-like superfamily TL08_03120 d88fb922505a91e83cef8c9d1415ecb6 126 PIRSF PIRSF002134 1 125 9.7E-44 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03120 d88fb922505a91e83cef8c9d1415ecb6 126 Gene3D G3DSA:4.10.910.10 73 126 2.1E-24 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03120 d88fb922505a91e83cef8c9d1415ecb6 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.5E-51 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03120 d88fb922505a91e83cef8c9d1415ecb6 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 26.277 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03120 d88fb922505a91e83cef8c9d1415ecb6 126 Gene3D G3DSA:1.10.8.50 1 72 1.1E-30 T 12-10-2018 TL08_03120 d88fb922505a91e83cef8c9d1415ecb6 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.7E-31 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TL08_03120 d88fb922505a91e83cef8c9d1415ecb6 126 SUPERFAMILY SSF46946 2 124 8.64E-46 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TL08_21370 bb0ad46ca443bccf0a2729d4c22bd5b4 119 SUPERFAMILY SSF53927 31 92 1.47E-9 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TL08_21370 bb0ad46ca443bccf0a2729d4c22bd5b4 119 Gene3D G3DSA:3.40.140.10 11 119 1.7E-8 T 12-10-2018 TL08_20060 1d2986d1647c31d61265bb024bf966ce 211 Gene3D G3DSA:1.10.520.40 30 199 4.8E-27 T 12-10-2018 IPR038287 Cse2 superfamily TL08_20060 1d2986d1647c31d61265bb024bf966ce 211 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 43 184 3.5E-16 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 TL08_20060 1d2986d1647c31d61265bb024bf966ce 211 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 43 183 3.7E-25 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 TL08_09600 0ffbe26f0192246a2dda9881b1cc840e 281 Pfam PF14062 Domain of unknown function (DUF4253) 173 281 5.8E-41 T 12-10-2018 IPR025349 Domain of unknown function DUF4253 TL08_00260 763d8d9db2af52c7af86301b337a3e08 393 SMART SM00382 43 230 8.6E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_00260 763d8d9db2af52c7af86301b337a3e08 393 Pfam PF00005 ABC transporter 35 180 1.6E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_00260 763d8d9db2af52c7af86301b337a3e08 393 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_00260 763d8d9db2af52c7af86301b337a3e08 393 Gene3D G3DSA:3.40.50.300 15 289 5.8E-75 T 12-10-2018 TL08_00260 763d8d9db2af52c7af86301b337a3e08 393 SUPERFAMILY SSF54631 266 380 4.93E-7 T 12-10-2018 TL08_00260 763d8d9db2af52c7af86301b337a3e08 393 SUPERFAMILY SSF52540 17 256 6.12E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_20270 8e7d6ab38555c031301e273d89d9bf67 729 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 447 692 1.0E-82 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related TL08_20270 8e7d6ab38555c031301e273d89d9bf67 729 Pfam PF05425 Copper resistance protein D 299 395 3.5E-12 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 TL08_19890 d0b73c0b330dd9eb2c69827ba2cd2101 192 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 27 188 3.2E-14 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TL08_19890 d0b73c0b330dd9eb2c69827ba2cd2101 192 SUPERFAMILY SSF48150 18 147 6.28E-15 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TL08_19890 d0b73c0b330dd9eb2c69827ba2cd2101 192 Gene3D G3DSA:1.10.340.30 18 139 1.8E-7 T 12-10-2018 TL08_19890 d0b73c0b330dd9eb2c69827ba2cd2101 192 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 5 191 4.6E-87 T 12-10-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD TL08_02790 c022764b2a7edaa0a987f7946d171144 290 Hamap MF_00188 Protease HtpX [htpX]. 7 283 27.91 T 12-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TL08_02790 c022764b2a7edaa0a987f7946d171144 290 Pfam PF01435 Peptidase family M48 68 283 1.6E-36 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TL08_02790 c022764b2a7edaa0a987f7946d171144 290 Gene3D G3DSA:3.30.2010.10 61 151 5.9E-28 T 12-10-2018 TL08_16535 f8951f825215256e0cff89d694466d6d 313 Gene3D G3DSA:3.30.200.150 20 95 1.4E-13 T 12-10-2018 TL08_16535 f8951f825215256e0cff89d694466d6d 313 Gene3D G3DSA:3.90.1200.10 50 240 1.4E-13 T 12-10-2018 TL08_16535 f8951f825215256e0cff89d694466d6d 313 SUPERFAMILY SSF56112 15 248 2.9E-25 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_16535 f8951f825215256e0cff89d694466d6d 313 Pfam PF01636 Phosphotransferase enzyme family 22 247 3.0E-15 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_19475 ac2e6ac620df9ca574f96d3cbbee1db0 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 296 2.1E-28 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_19475 ac2e6ac620df9ca574f96d3cbbee1db0 297 Gene3D G3DSA:1.10.3720.10 86 290 2.3E-18 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19475 ac2e6ac620df9ca574f96d3cbbee1db0 297 SUPERFAMILY SSF161098 90 278 1.19E-21 T 12-10-2018 IPR035906 MetI-like superfamily TL08_10465 b141200cd707f23080f653fe4e7f9c67 422 Gene3D G3DSA:3.40.47.10 263 419 2.1E-46 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_10465 b141200cd707f23080f653fe4e7f9c67 422 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 251 2.0E-48 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TL08_10465 b141200cd707f23080f653fe4e7f9c67 422 Gene3D G3DSA:3.40.47.10 1 259 8.9E-70 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_10465 b141200cd707f23080f653fe4e7f9c67 422 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 373 4.0E-34 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TL08_10465 b141200cd707f23080f653fe4e7f9c67 422 SUPERFAMILY SSF53901 3 256 8.47E-60 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_10465 b141200cd707f23080f653fe4e7f9c67 422 SMART SM00825 Beta-ketoacyl synthase 5 407 3.9E-13 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TL08_10465 b141200cd707f23080f653fe4e7f9c67 422 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 159 175 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TL08_10465 b141200cd707f23080f653fe4e7f9c67 422 SUPERFAMILY SSF53901 219 416 2.97E-65 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_13310 5e9685fe9ffef98b066fe04c9c42e755 239 Pfam PF08445 FR47-like protein 163 216 2.2E-6 T 12-10-2018 IPR013653 FR47-like GO:0016747 TL08_13310 5e9685fe9ffef98b066fe04c9c42e755 239 SUPERFAMILY SSF55729 118 225 1.51E-11 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_13310 5e9685fe9ffef98b066fe04c9c42e755 239 Gene3D G3DSA:3.40.630.30 26 232 1.2E-14 T 12-10-2018 TL08_23890 825374ea0386a6978fd628dfd45b76dc 402 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 220 3.5E-12 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TL08_23890 825374ea0386a6978fd628dfd45b76dc 402 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 126 1.6E-22 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TL08_23890 825374ea0386a6978fd628dfd45b76dc 402 Gene3D G3DSA:3.40.50.720 3 140 5.5E-39 T 12-10-2018 TL08_23890 825374ea0386a6978fd628dfd45b76dc 402 SUPERFAMILY SSF55347 142 315 5.89E-37 T 12-10-2018 TL08_23890 825374ea0386a6978fd628dfd45b76dc 402 Gene3D G3DSA:3.30.360.10 141 395 1.1E-74 T 12-10-2018 TL08_23890 825374ea0386a6978fd628dfd45b76dc 402 SUPERFAMILY SSF51735 5 168 8.15E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_08470 cdea4f1b1a809483c4a4ef4e6fa700c6 150 SUPERFAMILY SSF50118 37 140 2.62E-8 T 12-10-2018 TL08_08470 cdea4f1b1a809483c4a4ef4e6fa700c6 150 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 40 137 6.3E-7 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 TL08_24490 b2b427e5222f481996f1eb74d9a0fd98 272 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 3 245 3.0E-32 T 12-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 PRINTS PR00412 Epoxide hydrolase signature 94 107 7.7E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 PRINTS PR00412 Epoxide hydrolase signature 28 46 7.7E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 PRINTS PR00412 Epoxide hydrolase signature 108 121 7.7E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 PRINTS PR00412 Epoxide hydrolase signature 48 63 7.7E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 PRINTS PR00412 Epoxide hydrolase signature 249 271 7.7E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 1.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 1.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 Gene3D G3DSA:3.40.50.1820 2 272 4.5E-81 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 Pfam PF00561 alpha/beta hydrolase fold 23 138 6.0E-28 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05710 5bbbd7f554dc6c3ab8d6eed54aff2516 287 SUPERFAMILY SSF53474 5 273 2.82E-72 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18920 6967b9eb1811a9e346a7a8f271e93e0f 562 SUPERFAMILY SSF89372 390 557 1.07E-7 T 12-10-2018 TL08_18920 6967b9eb1811a9e346a7a8f271e93e0f 562 SUPERFAMILY SSF89372 215 430 9.02E-12 T 12-10-2018 TL08_19680 a976cf5d7edc40fddd6128c59bcc1ad6 324 Gene3D G3DSA:1.10.3720.10 91 299 9.6E-17 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19680 a976cf5d7edc40fddd6128c59bcc1ad6 324 SUPERFAMILY SSF161098 98 284 9.0E-23 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19680 a976cf5d7edc40fddd6128c59bcc1ad6 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 294 1.3E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_26785 17b4489dbd040124c8344797e3b1f7a0 710 SUPERFAMILY SSF63829 354 617 1.67E-5 T 12-10-2018 TL08_26785 17b4489dbd040124c8344797e3b1f7a0 710 Pfam PF05787 Bacterial protein of unknown function (DUF839) 117 667 1.7E-173 T 12-10-2018 IPR008557 Protein of unknown function DUF839 TL08_18520 5c7d5909bf9f0cd19c89757ccb98052d 216 SUPERFAMILY SSF46689 23 96 8.98E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_18520 5c7d5909bf9f0cd19c89757ccb98052d 216 Gene3D G3DSA:1.10.357.10 21 213 1.3E-34 T 12-10-2018 TL08_18520 5c7d5909bf9f0cd19c89757ccb98052d 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 78 2.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19445 4befdd91746d4c3254c6a3a9b1126f83 138 SUPERFAMILY SSF142906 1 122 1.44E-34 T 12-10-2018 IPR038056 YjbR-like superfamily TL08_19445 4befdd91746d4c3254c6a3a9b1126f83 138 Gene3D G3DSA:3.90.1150.30 1 130 2.2E-38 T 12-10-2018 IPR038056 YjbR-like superfamily TL08_19445 4befdd91746d4c3254c6a3a9b1126f83 138 Pfam PF04237 YjbR 11 108 1.0E-27 T 12-10-2018 IPR007351 Uncharacterised protein YjbR TL08_03775 c3a3878412e4188ee6aa9a81d9b7cc57 181 Pfam PF04977 Septum formation initiator 69 143 1.3E-15 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC TL08_20705 493cecc04cb966988d3096c5c39879da 425 Gene3D G3DSA:3.40.190.10 145 417 5.7E-119 T 12-10-2018 TL08_20705 493cecc04cb966988d3096c5c39879da 425 Pfam PF01547 Bacterial extracellular solute-binding protein 48 332 1.3E-31 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_20705 493cecc04cb966988d3096c5c39879da 425 Gene3D G3DSA:3.40.190.10 36 371 5.7E-119 T 12-10-2018 TL08_20705 493cecc04cb966988d3096c5c39879da 425 SUPERFAMILY SSF53850 23 424 6.21E-59 T 12-10-2018 TL08_11035 e0d710d6e91056ed4b8a3cfff7295675 302 Pfam PF03741 Integral membrane protein TerC family 15 201 7.4E-49 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TL08_10065 00486d3844d33a54a11c81d619e53655 538 Gene3D G3DSA:3.30.450.40 181 334 4.9E-10 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_10065 00486d3844d33a54a11c81d619e53655 538 SUPERFAMILY SSF55781 28 175 5.67E-14 T 12-10-2018 TL08_10065 00486d3844d33a54a11c81d619e53655 538 Gene3D G3DSA:3.30.565.10 401 525 1.4E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_10065 00486d3844d33a54a11c81d619e53655 538 SUPERFAMILY SSF55874 431 525 9.43E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_10065 00486d3844d33a54a11c81d619e53655 538 SUPERFAMILY SSF55781 182 329 3.93E-6 T 12-10-2018 TL08_10065 00486d3844d33a54a11c81d619e53655 538 Pfam PF07730 Histidine kinase 335 396 6.2E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_10065 00486d3844d33a54a11c81d619e53655 538 Gene3D G3DSA:3.30.450.40 82 158 1.5E-10 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_08655 82252ca968482dab38cb2d8195c1fc32 702 Gene3D G3DSA:3.40.50.1820 437 692 1.0E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_08655 82252ca968482dab38cb2d8195c1fc32 702 Gene3D G3DSA:2.120.10.30 30 190 2.4E-6 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_08655 82252ca968482dab38cb2d8195c1fc32 702 SUPERFAMILY SSF82171 48 406 5.1E-26 T 12-10-2018 TL08_08655 82252ca968482dab38cb2d8195c1fc32 702 Pfam PF00326 Prolyl oligopeptidase family 487 691 1.4E-45 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_08655 82252ca968482dab38cb2d8195c1fc32 702 SUPERFAMILY SSF53474 442 691 1.38E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_08655 82252ca968482dab38cb2d8195c1fc32 702 Gene3D G3DSA:2.120.10.30 192 431 5.7E-11 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_27100 d7b08222474007965a7975a9ab64150d 214 Gene3D G3DSA:3.40.630.30 21 188 4.7E-7 T 12-10-2018 TL08_27100 d7b08222474007965a7975a9ab64150d 214 SUPERFAMILY SSF55729 33 141 4.18E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_05810 603f5f04667c9f42584b191a34fb77f2 368 Pfam PF12697 Alpha/beta hydrolase family 68 340 1.2E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_05810 603f5f04667c9f42584b191a34fb77f2 368 SUPERFAMILY SSF53474 46 344 8.71E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05810 603f5f04667c9f42584b191a34fb77f2 368 Gene3D G3DSA:3.40.50.1820 44 349 6.7E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 Pfam PF00067 Cytochrome P450 221 370 3.7E-25 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00359 B-class P450 signature 196 218 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00359 B-class P450 signature 319 334 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00359 B-class P450 signature 95 106 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00359 B-class P450 signature 340 349 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00359 B-class P450 signature 142 158 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00359 B-class P450 signature 159 174 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00359 B-class P450 signature 349 360 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00359 B-class P450 signature 291 318 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00359 B-class P450 signature 273 284 1.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 Gene3D G3DSA:1.10.630.10 9 400 3.9E-123 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 SUPERFAMILY SSF48264 14 400 1.83E-94 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00385 P450 superfamily signature 349 360 9.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00385 P450 superfamily signature 340 349 9.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00385 P450 superfamily signature 273 284 9.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_11540 f032d99c2c0f090d0f5af24b71c00a2b 400 PRINTS PR00385 P450 superfamily signature 238 255 9.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_07605 05d7ff0a724e0c1d3ee23fa0e4a62815 312 Gene3D G3DSA:1.10.3720.10 23 303 9.9E-55 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07605 05d7ff0a724e0c1d3ee23fa0e4a62815 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 305 3.9E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_07605 05d7ff0a724e0c1d3ee23fa0e4a62815 312 SUPERFAMILY SSF161098 28 312 4.45E-49 T 12-10-2018 IPR035906 MetI-like superfamily TL08_12995 ac24f8386491ec842212c34304e69c20 290 Pfam PF01261 Xylose isomerase-like TIM barrel 74 246 4.3E-17 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_12995 ac24f8386491ec842212c34304e69c20 290 Gene3D G3DSA:3.20.20.150 31 290 7.1E-70 T 12-10-2018 TL08_12995 ac24f8386491ec842212c34304e69c20 290 SUPERFAMILY SSF51658 48 288 1.15E-39 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_15385 705691bbb1cf33dedd43126487d4aff0 429 Pfam PF13416 Bacterial extracellular solute-binding protein 54 354 7.2E-27 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_15385 705691bbb1cf33dedd43126487d4aff0 429 Gene3D G3DSA:3.40.190.10 50 373 1.8E-71 T 12-10-2018 TL08_15385 705691bbb1cf33dedd43126487d4aff0 429 Gene3D G3DSA:3.40.190.10 152 409 1.8E-71 T 12-10-2018 TL08_15385 705691bbb1cf33dedd43126487d4aff0 429 SUPERFAMILY SSF53850 25 422 1.72E-59 T 12-10-2018 TL08_09860 74f9ed3f73e0669dbe3184b1870cf59e 250 Gene3D G3DSA:3.40.50.150 7 238 2.7E-67 T 12-10-2018 TL08_09860 74f9ed3f73e0669dbe3184b1870cf59e 250 Pfam PF11599 RRNA methyltransferase AviRa 9 238 3.6E-20 T 12-10-2018 IPR024268 rRNA methyltransferase AviRa TL08_09860 74f9ed3f73e0669dbe3184b1870cf59e 250 Gene3D G3DSA:1.10.287.540 101 143 2.7E-67 T 12-10-2018 TL08_09860 74f9ed3f73e0669dbe3184b1870cf59e 250 SUPERFAMILY SSF53335 18 214 4.39E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_19070 bfc4323c57838449c687b9c3ead81d72 203 SUPERFAMILY SSF53335 1 194 1.67E-35 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_19070 bfc4323c57838449c687b9c3ead81d72 203 Pfam PF13847 Methyltransferase domain 37 145 8.3E-19 T 12-10-2018 IPR025714 Methyltransferase domain TL08_19070 bfc4323c57838449c687b9c3ead81d72 203 Gene3D G3DSA:3.40.50.150 5 200 3.2E-40 T 12-10-2018 TL08_17990 17b306dd9a0b31f10fd4acba9bdbcb04 667 Gene3D G3DSA:3.30.565.10 528 655 5.8E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_17990 17b306dd9a0b31f10fd4acba9bdbcb04 667 SUPERFAMILY SSF55874 563 654 5.46E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_17990 17b306dd9a0b31f10fd4acba9bdbcb04 667 Pfam PF07730 Histidine kinase 451 517 1.6E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_01465 909a4232384ec772630e8c6fb0441f5d 237 Pfam PF00482 Type II secretion system (T2SS), protein F 102 220 1.1E-14 T 12-10-2018 IPR018076 Type II secretion system F domain TL08_12655 acb7d1c7ba281511545d073f58aa199f 339 Gene3D G3DSA:3.40.190.10 119 218 3.6E-88 T 12-10-2018 TL08_12655 acb7d1c7ba281511545d073f58aa199f 339 Gene3D G3DSA:3.40.190.10 44 313 3.6E-88 T 12-10-2018 TL08_12655 acb7d1c7ba281511545d073f58aa199f 339 Gene3D G3DSA:1.10.8.450 252 285 3.6E-88 T 12-10-2018 TL08_12655 acb7d1c7ba281511545d073f58aa199f 339 SUPERFAMILY SSF53850 42 263 8.46E-43 T 12-10-2018 TL08_12655 acb7d1c7ba281511545d073f58aa199f 339 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 45 325 2.8E-54 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 TL08_12655 acb7d1c7ba281511545d073f58aa199f 339 Pfam PF13379 NMT1-like family 60 256 2.6E-11 T 12-10-2018 TL08_12655 acb7d1c7ba281511545d073f58aa199f 339 SMART SM00062 41 269 3.5E-7 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_24755 b19a98f09e54fe9293e189231faaf101 331 SUPERFAMILY SSF103481 41 131 1.7E-13 T 12-10-2018 TL08_24755 b19a98f09e54fe9293e189231faaf101 331 SUPERFAMILY SSF103481 173 277 4.05E-14 T 12-10-2018 TL08_24755 b19a98f09e54fe9293e189231faaf101 331 Pfam PF00892 EamA-like transporter family 4 128 1.0E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_24755 b19a98f09e54fe9293e189231faaf101 331 Pfam PF00892 EamA-like transporter family 139 270 1.5E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_06825 0d9c68b324c1274ffb84da75c161ab18 384 Gene3D G3DSA:3.30.565.10 256 380 3.5E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_06825 0d9c68b324c1274ffb84da75c161ab18 384 SUPERFAMILY SSF55874 263 379 1.74E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_06825 0d9c68b324c1274ffb84da75c161ab18 384 Pfam PF07730 Histidine kinase 184 248 2.7E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_23280 bd4c56b4669c5a3fa0eb0fa43bd95efc 272 Pfam PF01764 Lipase (class 3) 75 208 5.5E-29 T 12-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 TL08_23280 bd4c56b4669c5a3fa0eb0fa43bd95efc 272 Gene3D G3DSA:3.40.50.1820 10 232 2.1E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_23280 bd4c56b4669c5a3fa0eb0fa43bd95efc 272 SUPERFAMILY SSF53474 11 222 1.46E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13220 9c3350f6ad4ac7e6d719472ed413f42c 268 Pfam PF00296 Luciferase-like monooxygenase 5 236 2.0E-40 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_13220 9c3350f6ad4ac7e6d719472ed413f42c 268 Gene3D G3DSA:3.20.20.30 1 264 2.7E-52 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_13220 9c3350f6ad4ac7e6d719472ed413f42c 268 SUPERFAMILY SSF51679 2 264 2.36E-46 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_03985 bdf2347976f75651b901ee08f6d0a7eb 158 Pfam PF14430 Immunity protein Imm1 14 145 1.3E-15 T 12-10-2018 IPR025680 Immunity protein Imm1 TL08_17180 8a3bdbbe43c2867fa22c5c423b140df8 397 SUPERFAMILY SSF51445 2 368 1.35E-81 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_17180 8a3bdbbe43c2867fa22c5c423b140df8 397 Gene3D G3DSA:3.20.20.80 1 364 3.7E-81 T 12-10-2018 TL08_17180 8a3bdbbe43c2867fa22c5c423b140df8 397 SMART SM00642 11 359 4.4E-52 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_17180 8a3bdbbe43c2867fa22c5c423b140df8 397 Pfam PF00128 Alpha amylase, catalytic domain 39 320 1.6E-46 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_25025 a1dc2988f5252a76f91559bbd45ce356 160 Gene3D G3DSA:2.30.110.10 16 149 4.1E-35 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_25025 a1dc2988f5252a76f91559bbd45ce356 160 SUPERFAMILY SSF50475 21 146 7.11E-29 T 12-10-2018 TL08_25025 a1dc2988f5252a76f91559bbd45ce356 160 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 20 102 2.6E-15 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_25025 a1dc2988f5252a76f91559bbd45ce356 160 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 23 147 2.0E-35 T 12-10-2018 IPR019920 F420-binding domain, putative TL08_24530 fc79df94db6976b3539322f7e63b7c45 423 Pfam PF07690 Major Facilitator Superfamily 29 373 2.5E-22 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_24530 fc79df94db6976b3539322f7e63b7c45 423 Gene3D G3DSA:1.20.1250.20 13 408 1.0E-28 T 12-10-2018 TL08_24530 fc79df94db6976b3539322f7e63b7c45 423 SUPERFAMILY SSF103473 16 407 2.09E-34 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_05215 4c3bd4065276694a9bd74c317c2fd7ba 53 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 30 5.1E-9 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_05215 4c3bd4065276694a9bd74c317c2fd7ba 53 Pfam PF01783 Ribosomal L32p protein family 2 47 7.5E-12 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_05215 4c3bd4065276694a9bd74c317c2fd7ba 53 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 53 12.59 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_05215 4c3bd4065276694a9bd74c317c2fd7ba 53 SUPERFAMILY SSF57829 1 35 4.64E-8 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TL08_25740 d2d9335cf6f7f0c60941ea649e66a410 390 Gene3D G3DSA:2.40.110.10 133 236 7.1E-35 T 12-10-2018 TL08_25740 d2d9335cf6f7f0c60941ea649e66a410 390 Gene3D G3DSA:1.10.540.10 1 131 6.0E-40 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TL08_25740 d2d9335cf6f7f0c60941ea649e66a410 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 223 2.3E-23 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TL08_25740 d2d9335cf6f7f0c60941ea649e66a410 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 136 148 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TL08_25740 d2d9335cf6f7f0c60941ea649e66a410 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 130 4.9E-29 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TL08_25740 d2d9335cf6f7f0c60941ea649e66a410 390 Gene3D G3DSA:1.20.140.10 238 390 2.1E-37 T 12-10-2018 TL08_25740 d2d9335cf6f7f0c60941ea649e66a410 390 SUPERFAMILY SSF56645 8 234 4.06E-74 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TL08_25740 d2d9335cf6f7f0c60941ea649e66a410 390 SUPERFAMILY SSF47203 240 388 1.93E-39 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TL08_25740 d2d9335cf6f7f0c60941ea649e66a410 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 382 2.4E-26 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TL08_22910 076df3f94c25dbb4b19be41ccb0c636a 208 Pfam PF12079 Protein of unknown function (DUF3558) 6 200 1.4E-11 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 TL08_16725 92d21bef67357bf73ae6686a1426a5ca 189 SUPERFAMILY SSF46689 3 75 2.67E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16725 92d21bef67357bf73ae6686a1426a5ca 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 8.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16725 92d21bef67357bf73ae6686a1426a5ca 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 8.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16725 92d21bef67357bf73ae6686a1426a5ca 189 SUPERFAMILY SSF48498 86 183 5.12E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_16725 92d21bef67357bf73ae6686a1426a5ca 189 Pfam PF13305 WHG domain 98 165 4.7E-6 T 12-10-2018 IPR025996 WHG domain TL08_16725 92d21bef67357bf73ae6686a1426a5ca 189 Gene3D G3DSA:1.10.357.10 2 186 2.2E-35 T 12-10-2018 TL08_16725 92d21bef67357bf73ae6686a1426a5ca 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 1.7E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_03590 739757ad8a71eaa526542c9713754060 66 Pfam PF04149 Domain of unknown function (DUF397) 11 61 3.6E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_09310 a953ae19a68654346451b32e4b973257 161 Pfam PF09335 SNARE associated Golgi protein 35 150 7.4E-8 T 12-10-2018 IPR032816 SNARE associated Golgi protein TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 SUPERFAMILY SSF56634 5 481 5.1E-199 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 PIRSF PIRSF038928 1 483 1.2E-230 T 12-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 Gene3D G3DSA:2.40.180.10 1 483 1.4E-215 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 PRINTS PR00067 Catalase signature 123 141 1.6E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 PRINTS PR00067 Catalase signature 104 121 1.6E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 PRINTS PR00067 Catalase signature 320 346 1.6E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 PRINTS PR00067 Catalase signature 288 315 1.6E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 PRINTS PR00067 Catalase signature 21 44 1.6E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 PRINTS PR00067 Catalase signature 83 101 1.6E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 Pfam PF06628 Catalase-related immune-responsive 418 479 3.7E-17 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 SMART SM01060 8 389 1.9E-275 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_01150 1ad1b7bd5fa047a08dcdbc777d3f30c6 483 Pfam PF00199 Catalase 8 385 3.3E-182 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 TL08_05965 c3752a0159ade5579093bf373ab6df3f 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_05965 c3752a0159ade5579093bf373ab6df3f 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_05965 c3752a0159ade5579093bf373ab6df3f 201 SUPERFAMILY SSF46689 9 83 2.57E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_05965 c3752a0159ade5579093bf373ab6df3f 201 Gene3D G3DSA:1.10.357.10 6 191 6.3E-41 T 12-10-2018 TL08_05965 c3752a0159ade5579093bf373ab6df3f 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 6.6E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_05965 c3752a0159ade5579093bf373ab6df3f 201 SUPERFAMILY SSF48498 83 185 2.37E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_24535 b08be598394cbd4394948cb290c6c8b2 162 SUPERFAMILY SSF160424 13 153 1.15E-21 T 12-10-2018 IPR036170 Probable antitoxin YezG superfamily TL08_13995 cef87e17f11fa2e2ce5bdd83f2ef21c9 209 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 14 208 2.4E-72 T 12-10-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent TL08_13995 cef87e17f11fa2e2ce5bdd83f2ef21c9 209 Gene3D G3DSA:2.30.110.10 34 159 1.2E-28 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_13995 cef87e17f11fa2e2ce5bdd83f2ef21c9 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 127 1.8E-15 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 TL08_13995 cef87e17f11fa2e2ce5bdd83f2ef21c9 209 SUPERFAMILY SSF50475 39 154 1.12E-19 T 12-10-2018 TL08_03155 e14c02d05ba2a84161f0da8324264027 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 193 2.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03155 e14c02d05ba2a84161f0da8324264027 212 SMART SM00448 1 120 4.2E-9 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_03155 e14c02d05ba2a84161f0da8324264027 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 6.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03155 e14c02d05ba2a84161f0da8324264027 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 6.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03155 e14c02d05ba2a84161f0da8324264027 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 6.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03155 e14c02d05ba2a84161f0da8324264027 212 Pfam PF00072 Response regulator receiver domain 3 108 4.0E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TL08_03155 e14c02d05ba2a84161f0da8324264027 212 SUPERFAMILY SSF52172 2 174 2.28E-16 T 12-10-2018 IPR011006 CheY-like superfamily TL08_03155 e14c02d05ba2a84161f0da8324264027 212 SMART SM00421 146 208 7.8E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_03155 e14c02d05ba2a84161f0da8324264027 212 Gene3D G3DSA:3.40.50.12740 1 209 9.3E-44 T 12-10-2018 TL08_03155 e14c02d05ba2a84161f0da8324264027 212 SUPERFAMILY SSF46894 138 194 4.42E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_08150 e0a7bef26371e23e092a14f94d8c5dce 264 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 1 136 1.4E-30 T 12-10-2018 IPR018768 Domain of unknown function DUF2344 TL08_08150 e0a7bef26371e23e092a14f94d8c5dce 264 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 1 147 2.7E-26 T 12-10-2018 IPR018768 Domain of unknown function DUF2344 TL08_05505 2377f4558384375c7054f7221c669f44 386 Gene3D G3DSA:3.30.565.10 257 373 1.5E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_05505 2377f4558384375c7054f7221c669f44 386 Pfam PF07730 Histidine kinase 193 256 3.6E-10 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_06985 2f00180a4ac14681ce0d1f6d403e99bb 178 Pfam PF03703 Bacterial PH domain 88 161 2.5E-13 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_19170 de3e1ea6a0c22fb54214dfa5bc32c6d0 459 Pfam PF03600 Citrate transporter 15 400 5.3E-43 T 12-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TL08_19170 de3e1ea6a0c22fb54214dfa5bc32c6d0 459 TIGRFAM TIGR00784 citMHS: citrate transporter 1 455 8.5E-113 T 12-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 TL08_24060 29954f2368f7dfbda72d3bb0d61cafe9 542 Gene3D G3DSA:3.90.226.10 286 542 8.4E-89 T 12-10-2018 TL08_24060 29954f2368f7dfbda72d3bb0d61cafe9 542 SUPERFAMILY SSF52096 36 280 7.01E-73 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_24060 29954f2368f7dfbda72d3bb0d61cafe9 542 SUPERFAMILY SSF52096 279 542 3.62E-84 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_24060 29954f2368f7dfbda72d3bb0d61cafe9 542 Gene3D G3DSA:3.90.226.10 28 284 2.4E-87 T 12-10-2018 TL08_24060 29954f2368f7dfbda72d3bb0d61cafe9 542 Pfam PF01039 Carboxyl transferase domain 56 539 1.9E-179 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TL08_21730 d7a2d81d725f98ad7622fb95092523bd 551 Pfam PF05991 YacP-like NYN domain 431 548 4.6E-18 T 12-10-2018 IPR010298 Protein of unknown function DUF901 TL08_14410 25fa96d52e7fcd5fcb9ee65aa7fc7b8e 243 SUPERFAMILY SSF53335 6 159 1.04E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_14410 25fa96d52e7fcd5fcb9ee65aa7fc7b8e 243 Gene3D G3DSA:3.40.50.150 27 176 1.4E-15 T 12-10-2018 TL08_14410 25fa96d52e7fcd5fcb9ee65aa7fc7b8e 243 Pfam PF13649 Methyltransferase domain 42 136 4.4E-7 T 12-10-2018 TL08_01880 05fd4009496ed0f5042044ec13ac5cf4 246 Gene3D G3DSA:3.40.50.150 6 207 6.0E-32 T 12-10-2018 TL08_01880 05fd4009496ed0f5042044ec13ac5cf4 246 SUPERFAMILY SSF53335 6 189 1.01E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_01880 05fd4009496ed0f5042044ec13ac5cf4 246 Pfam PF13649 Methyltransferase domain 41 135 2.0E-17 T 12-10-2018 TL08_14720 ddfe668cb034ce86f9c2b946abe97c75 394 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 143 3.5E-27 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_14720 ddfe668cb034ce86f9c2b946abe97c75 394 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_14720 ddfe668cb034ce86f9c2b946abe97c75 394 Gene3D G3DSA:3.40.50.720 169 353 2.2E-120 T 12-10-2018 TL08_14720 ddfe668cb034ce86f9c2b946abe97c75 394 SUPERFAMILY SSF50129 1 175 2.28E-57 T 12-10-2018 IPR011032 GroES-like superfamily TL08_14720 ddfe668cb034ce86f9c2b946abe97c75 394 Gene3D G3DSA:3.90.180.10 4 382 2.2E-120 T 12-10-2018 TL08_14720 ddfe668cb034ce86f9c2b946abe97c75 394 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 22 4.7E-12 T 12-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated TL08_14720 ddfe668cb034ce86f9c2b946abe97c75 394 SUPERFAMILY SSF51735 156 352 2.42E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14720 ddfe668cb034ce86f9c2b946abe97c75 394 Pfam PF00107 Zinc-binding dehydrogenase 189 259 2.4E-12 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_01225 322382d1ecd7154b9b65d4abf9263330 334 Pfam PF02374 Anion-transporting ATPase 18 177 3.8E-16 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 TL08_01225 322382d1ecd7154b9b65d4abf9263330 334 SUPERFAMILY SSF52540 18 238 3.68E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_22545 40f0f665a5b25ba3c9f4ac46baf38557 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 45 1.4E-6 T 12-10-2018 IPR001451 Hexapeptide repeat TL08_22545 40f0f665a5b25ba3c9f4ac46baf38557 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 122 5.9E-7 T 12-10-2018 IPR001451 Hexapeptide repeat TL08_22545 40f0f665a5b25ba3c9f4ac46baf38557 174 Gene3D G3DSA:2.160.10.10 2 169 3.0E-49 T 12-10-2018 TL08_22545 40f0f665a5b25ba3c9f4ac46baf38557 174 SUPERFAMILY SSF51161 2 152 6.38E-42 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TL08_01155 84996c3661145b6f6d580596477c151d 87 Gene3D G3DSA:2.10.230.20 35 83 4.5E-5 T 12-10-2018 TL08_19895 21c16fb0f10a8ce295c6d2b79bc8a358 383 Pfam PF03235 Protein of unknown function DUF262 39 187 2.5E-19 T 12-10-2018 IPR004919 Domain of unknown function DUF262 TL08_26480 e0dd64ec960ebd65fe7117361bd46ba5 241 Gene3D G3DSA:3.40.50.150 4 220 7.3E-15 T 12-10-2018 TL08_26480 e0dd64ec960ebd65fe7117361bd46ba5 241 Pfam PF08241 Methyltransferase domain 45 169 7.6E-6 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_26480 e0dd64ec960ebd65fe7117361bd46ba5 241 SUPERFAMILY SSF53335 13 169 8.29E-14 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_24835 5ede048e6dcfd860e01e4a52e790f9ed 543 SUPERFAMILY SSF51645 21 542 2.22E-154 T 12-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TL08_24835 5ede048e6dcfd860e01e4a52e790f9ed 543 Gene3D G3DSA:3.20.20.360 13 421 4.3E-160 T 12-10-2018 TL08_24835 5ede048e6dcfd860e01e4a52e790f9ed 543 PIRSF PIRSF001363 9 543 1.9E-192 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TL08_24835 5ede048e6dcfd860e01e4a52e790f9ed 543 Gene3D G3DSA:1.20.1220.12 425 542 4.8E-32 T 12-10-2018 TL08_24835 5ede048e6dcfd860e01e4a52e790f9ed 543 Pfam PF01274 Malate synthase 20 542 1.6E-162 T 12-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TL08_24835 5ede048e6dcfd860e01e4a52e790f9ed 543 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 31 542 5.3E-192 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TL08_17945 6ae2ab8f8e0e806c60ee89b0cb388983 518 Pfam PF00171 Aldehyde dehydrogenase family 22 491 1.3E-129 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TL08_17945 6ae2ab8f8e0e806c60ee89b0cb388983 518 SUPERFAMILY SSF53720 6 493 2.23E-133 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TL08_17945 6ae2ab8f8e0e806c60ee89b0cb388983 518 Gene3D G3DSA:3.40.605.10 24 485 8.4E-136 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TL08_17945 6ae2ab8f8e0e806c60ee89b0cb388983 518 Gene3D G3DSA:3.40.309.10 258 459 8.4E-136 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TL08_17945 6ae2ab8f8e0e806c60ee89b0cb388983 518 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TL08_11985 5b75d9da0229cd489bcbbcc2e557feec 315 SMART SM00382 29 228 4.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_11985 5b75d9da0229cd489bcbbcc2e557feec 315 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 308 1.6E-104 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TL08_11985 5b75d9da0229cd489bcbbcc2e557feec 315 Gene3D G3DSA:3.40.50.300 2 244 1.2E-65 T 12-10-2018 TL08_11985 5b75d9da0229cd489bcbbcc2e557feec 315 Pfam PF00005 ABC transporter 20 163 8.6E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_11985 5b75d9da0229cd489bcbbcc2e557feec 315 SUPERFAMILY SSF52540 4 225 2.19E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_09200 ec37d2c6dbd3e42270a1f55997a4329b 150 Pfam PF00583 Acetyltransferase (GNAT) family 21 106 1.4E-9 T 12-10-2018 IPR000182 GNAT domain TL08_09200 ec37d2c6dbd3e42270a1f55997a4329b 150 Gene3D G3DSA:3.40.630.30 1 149 1.8E-42 T 12-10-2018 TL08_09200 ec37d2c6dbd3e42270a1f55997a4329b 150 SUPERFAMILY SSF55729 4 114 7.2E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_03040 fda4322c8e74f03723c1b4815036a9bc 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_03040 fda4322c8e74f03723c1b4815036a9bc 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 104 5.8E-36 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03040 fda4322c8e74f03723c1b4815036a9bc 104 Pfam PF00467 KOW motif 5 36 9.8E-9 T 12-10-2018 IPR005824 KOW TL08_03040 fda4322c8e74f03723c1b4815036a9bc 104 SUPERFAMILY SSF50104 1 99 1.2E-29 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TL08_03040 fda4322c8e74f03723c1b4815036a9bc 104 Gene3D G3DSA:2.30.30.30 1 103 5.9E-34 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 TL08_03040 fda4322c8e74f03723c1b4815036a9bc 104 SMART SM00739 2 29 1.6E-4 T 12-10-2018 IPR005824 KOW TL08_03040 fda4322c8e74f03723c1b4815036a9bc 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 104 9.0E-24 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_03040 fda4322c8e74f03723c1b4815036a9bc 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 98 20.982 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_05520 b3ac2882adfcfef8100931e9f1032f51 247 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 9.6E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_05520 b3ac2882adfcfef8100931e9f1032f51 247 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 9.6E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_05520 b3ac2882adfcfef8100931e9f1032f51 247 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 9.6E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_05520 b3ac2882adfcfef8100931e9f1032f51 247 SUPERFAMILY SSF46955 4 106 6.59E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_05520 b3ac2882adfcfef8100931e9f1032f51 247 Pfam PF13411 MerR HTH family regulatory protein 4 68 4.8E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_05520 b3ac2882adfcfef8100931e9f1032f51 247 SMART SM00422 3 72 7.8E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_05480 8681a4ea66bc9f82aa52cc7b3c83e77f 630 Gene3D G3DSA:2.120.10.30 8 134 9.3E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_05480 8681a4ea66bc9f82aa52cc7b3c83e77f 630 Pfam PF00326 Prolyl oligopeptidase family 409 625 2.4E-49 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TL08_05480 8681a4ea66bc9f82aa52cc7b3c83e77f 630 SUPERFAMILY SSF53474 365 624 1.24E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05480 8681a4ea66bc9f82aa52cc7b3c83e77f 630 Gene3D G3DSA:3.40.50.1820 338 629 3.6E-78 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_05480 8681a4ea66bc9f82aa52cc7b3c83e77f 630 SUPERFAMILY SSF82171 20 352 1.15E-19 T 12-10-2018 TL08_21170 29b52ebf59a7b6d31d114e9fc9342ab0 214 PIRSF PIRSF031644 12 214 7.5E-59 T 12-10-2018 IPR008319 Uncharacterised conserved protein UCP031644 TL08_21170 29b52ebf59a7b6d31d114e9fc9342ab0 214 Pfam PF06445 GyrI-like small molecule binding domain 31 210 1.8E-18 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain TL08_21170 29b52ebf59a7b6d31d114e9fc9342ab0 214 SUPERFAMILY SSF55136 125 205 2.09E-9 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily TL08_21170 29b52ebf59a7b6d31d114e9fc9342ab0 214 Gene3D G3DSA:3.20.80.10 8 214 5.3E-76 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily TL08_14455 037dff03318ea79a781bdcb433de94d8 339 Pfam PF01794 Ferric reductase like transmembrane component 95 230 1.8E-10 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain TL08_23320 90bad5b0a6bc94f09aac1669fcb7c5f0 114 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 18 103 9.8E-7 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 TL08_17385 7099954af2472b823d28b47b7805fb6e 295 Pfam PF01936 NYN domain 3 165 2.5E-12 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type TL08_17385 7099954af2472b823d28b47b7805fb6e 295 Gene3D G3DSA:3.40.50.1010 43 172 2.4E-7 T 12-10-2018 TL08_01320 ca9ae57304db798beea52884b86a5ab3 176 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 41 154 4.4E-29 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III TL08_14385 863c2651e57bb5c34c951b1cc0d9d6a8 207 SUPERFAMILY SSF56349 46 199 2.47E-15 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_14385 863c2651e57bb5c34c951b1cc0d9d6a8 207 Gene3D G3DSA:1.10.150.130 41 149 2.5E-9 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TL08_15365 c29033630d95c87c779801a52aaa3f39 118 Gene3D G3DSA:2.30.110.10 1 114 9.2E-31 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_15365 c29033630d95c87c779801a52aaa3f39 118 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 4 112 4.4E-26 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_15365 c29033630d95c87c779801a52aaa3f39 118 Pfam PF04075 F420H(2)-dependent quinone reductase 3 113 1.1E-27 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_10990 89d74a55d38b859df49e50826ca31364 427 Gene3D G3DSA:3.90.1150.10 16 417 7.4E-154 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_10990 89d74a55d38b859df49e50826ca31364 427 SUPERFAMILY SSF53383 20 422 4.18E-133 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_10990 89d74a55d38b859df49e50826ca31364 427 Gene3D G3DSA:3.40.640.10 58 321 7.4E-154 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_10990 89d74a55d38b859df49e50826ca31364 427 PIRSF PIRSF000521 11 130 1.9E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_10990 89d74a55d38b859df49e50826ca31364 427 PIRSF PIRSF000521 120 424 5.5E-42 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_10990 89d74a55d38b859df49e50826ca31364 427 Pfam PF00202 Aminotransferase class-III 21 422 2.1E-125 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_10990 89d74a55d38b859df49e50826ca31364 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TL08_15115 7265efb5c70ba65978f117ba5e10c35f 283 Gene3D G3DSA:1.10.260.40 7 75 1.9E-7 T 12-10-2018 TL08_15115 7265efb5c70ba65978f117ba5e10c35f 283 Pfam PF13560 Helix-turn-helix domain 11 70 2.1E-10 T 12-10-2018 TL08_15115 7265efb5c70ba65978f117ba5e10c35f 283 SUPERFAMILY SSF47413 9 66 2.49E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_26970 07bc553ba82166b82881a67619d0a0de 314 Gene3D G3DSA:3.40.50.2300 138 273 2.0E-89 T 12-10-2018 TL08_26970 07bc553ba82166b82881a67619d0a0de 314 Pfam PF13407 Periplasmic binding protein domain 40 291 4.9E-64 T 12-10-2018 IPR025997 Periplasmic binding protein TL08_26970 07bc553ba82166b82881a67619d0a0de 314 Gene3D G3DSA:3.40.50.2300 43 291 2.0E-89 T 12-10-2018 TL08_26970 07bc553ba82166b82881a67619d0a0de 314 SUPERFAMILY SSF53822 38 312 2.77E-85 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 Pfam PF02867 Ribonucleotide reductase, barrel domain 171 706 2.7E-141 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 92 716 3.1E-182 T 12-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 SUPERFAMILY SSF51998 171 718 2.32E-128 T 12-10-2018 TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 407 430 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 246 265 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 552 579 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 445 467 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 373 384 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 Gene3D G3DSA:3.20.70.20 76 722 6.5E-195 T 12-10-2018 TL08_08595 b6b2ec47e4110d9e545d43ac680c6508 957 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 67 150 6.2E-19 T 12-10-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TL08_19210 d83a864c2a0773968f09dddcc908b3fc 196 Gene3D G3DSA:1.10.357.10 28 194 6.5E-16 T 12-10-2018 TL08_19210 d83a864c2a0773968f09dddcc908b3fc 196 SUPERFAMILY SSF46689 5 78 1.28E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_05070 040f170df0678f2bb3823a22ea831b0a 86 Pfam PF00550 Phosphopantetheine attachment site 16 77 1.7E-16 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_05070 040f170df0678f2bb3823a22ea831b0a 86 SUPERFAMILY SSF47336 9 79 1.11E-19 T 12-10-2018 IPR036736 ACP-like superfamily TL08_05070 040f170df0678f2bb3823a22ea831b0a 86 ProSitePatterns PS00012 Phosphopantetheine attachment site. 37 52 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TL08_05070 040f170df0678f2bb3823a22ea831b0a 86 SMART SM00823 Phosphopantetheine attachment site 13 82 6.8E-8 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 TL08_05070 040f170df0678f2bb3823a22ea831b0a 86 Gene3D G3DSA:1.10.1200.10 2 85 3.0E-25 T 12-10-2018 IPR036736 ACP-like superfamily TL08_07185 b4fd4aa8080b3e2c51e45a48f9f4fc5b 314 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 140 166 9.2E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TL08_07185 b4fd4aa8080b3e2c51e45a48f9f4fc5b 314 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 190 218 9.2E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TL08_07185 b4fd4aa8080b3e2c51e45a48f9f4fc5b 314 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 122 140 9.2E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TL08_07185 b4fd4aa8080b3e2c51e45a48f9f4fc5b 314 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 30 57 9.2E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TL08_07185 b4fd4aa8080b3e2c51e45a48f9f4fc5b 314 ProSitePatterns PS01218 TatC family signature. 190 209 - T 12-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site TL08_07185 b4fd4aa8080b3e2c51e45a48f9f4fc5b 314 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 21 275 14.328 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TL08_07185 b4fd4aa8080b3e2c51e45a48f9f4fc5b 314 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 31 263 2.2E-56 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TL08_07185 b4fd4aa8080b3e2c51e45a48f9f4fc5b 314 Pfam PF00902 Sec-independent protein translocase protein (TatC) 33 256 2.0E-53 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TL08_23105 1ade1baca2620b76e17bd56ee5ec62f2 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 214 1.3E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_23105 1ade1baca2620b76e17bd56ee5ec62f2 246 Gene3D G3DSA:1.10.3720.10 23 210 2.5E-25 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23105 1ade1baca2620b76e17bd56ee5ec62f2 246 SUPERFAMILY SSF161098 24 203 1.14E-32 T 12-10-2018 IPR035906 MetI-like superfamily TL08_24980 52119a1d7591801d8b9f96c8df1c2661 401 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 9 399 6.7E-53 T 12-10-2018 IPR021368 Type VII secretion system protein EccE TL08_24980 52119a1d7591801d8b9f96c8df1c2661 401 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 207 309 7.0E-21 T 12-10-2018 IPR021368 Type VII secretion system protein EccE TL08_00770 775d7df77c5249e00a0fd38cb9d03edd 98 SUPERFAMILY SSF89360 1 87 1.96E-7 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TL08_00770 775d7df77c5249e00a0fd38cb9d03edd 98 Gene3D G3DSA:2.60.300.12 1 97 2.1E-7 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TL08_01485 b06585bfbd09ed94100e70fa6afc032f 213 SMART SM00943 19 208 1.1E-5 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TL08_21340 09222bdc1ddfa38f4fc37f98242fe657 120 SUPERFAMILY SSF46785 4 75 5.44E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_21340 09222bdc1ddfa38f4fc37f98242fe657 120 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 2.6E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_21340 09222bdc1ddfa38f4fc37f98242fe657 120 Gene3D G3DSA:1.10.10.10 5 120 1.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21340 09222bdc1ddfa38f4fc37f98242fe657 120 SMART SM00345 12 71 2.2E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_14025 47089e23736c00f8d14b271cd562d478 254 Gene3D G3DSA:3.40.50.720 2 253 1.5E-70 T 12-10-2018 TL08_14025 47089e23736c00f8d14b271cd562d478 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 7.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14025 47089e23736c00f8d14b271cd562d478 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 7.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14025 47089e23736c00f8d14b271cd562d478 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 7.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14025 47089e23736c00f8d14b271cd562d478 254 SUPERFAMILY SSF51735 5 252 2.01E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_14025 47089e23736c00f8d14b271cd562d478 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14025 47089e23736c00f8d14b271cd562d478 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14025 47089e23736c00f8d14b271cd562d478 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14025 47089e23736c00f8d14b271cd562d478 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14025 47089e23736c00f8d14b271cd562d478 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14025 47089e23736c00f8d14b271cd562d478 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_14025 47089e23736c00f8d14b271cd562d478 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 8.9E-51 T 12-10-2018 TL08_14065 74b977fca73a067015e26d1363203349 179 Gene3D G3DSA:3.40.630.30 2 171 1.8E-34 T 12-10-2018 TL08_14065 74b977fca73a067015e26d1363203349 179 SUPERFAMILY SSF55729 9 157 1.27E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_14065 74b977fca73a067015e26d1363203349 179 Pfam PF13302 Acetyltransferase (GNAT) domain 15 155 6.7E-21 T 12-10-2018 IPR000182 GNAT domain TL08_25340 f2ee80811477999e5ba9bd8a3b6df968 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 252 6.5E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_25340 f2ee80811477999e5ba9bd8a3b6df968 274 Gene3D G3DSA:1.10.3720.10 61 257 4.2E-18 T 12-10-2018 IPR035906 MetI-like superfamily TL08_25340 f2ee80811477999e5ba9bd8a3b6df968 274 SUPERFAMILY SSF161098 64 246 2.09E-24 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13255 e6c0662ef515afe36735bc81d2d680fd 636 SMART SM00382 406 592 4.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_13255 e6c0662ef515afe36735bc81d2d680fd 636 Gene3D G3DSA:1.20.1560.10 13 348 1.1E-75 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_13255 e6c0662ef515afe36735bc81d2d680fd 636 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_13255 e6c0662ef515afe36735bc81d2d680fd 636 SUPERFAMILY SSF90123 30 350 1.19E-70 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TL08_13255 e6c0662ef515afe36735bc81d2d680fd 636 Pfam PF00664 ABC transporter transmembrane region 47 315 1.5E-39 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TL08_13255 e6c0662ef515afe36735bc81d2d680fd 636 SUPERFAMILY SSF52540 355 617 1.63E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13255 e6c0662ef515afe36735bc81d2d680fd 636 Gene3D G3DSA:3.40.50.300 358 628 2.6E-83 T 12-10-2018 TL08_13255 e6c0662ef515afe36735bc81d2d680fd 636 Pfam PF00005 ABC transporter 397 546 8.5E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_07765 9c52656ee61fd9e35137a48f4ef79166 345 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 6 338 4.0E-149 T 12-10-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative TL08_07765 9c52656ee61fd9e35137a48f4ef79166 345 Pfam PF00296 Luciferase-like monooxygenase 22 301 1.7E-43 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_07765 9c52656ee61fd9e35137a48f4ef79166 345 SUPERFAMILY SSF51679 6 339 2.88E-70 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_07765 9c52656ee61fd9e35137a48f4ef79166 345 Gene3D G3DSA:3.20.20.30 2 343 6.6E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_06265 1e6caca2457cff7cc9c72b7840829b48 189 Pfam PF04314 Copper chaperone PCu(A)C 53 160 1.3E-35 T 12-10-2018 IPR007410 Copper chaperone PCuAC TL08_06265 1e6caca2457cff7cc9c72b7840829b48 189 SUPERFAMILY SSF110087 42 169 3.01E-38 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily TL08_06265 1e6caca2457cff7cc9c72b7840829b48 189 Gene3D G3DSA:2.60.40.1890 57 171 6.7E-34 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily TL08_03695 59e11ac146a5862bb01bc10485023af0 326 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 12 323 44.496 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TL08_03695 59e11ac146a5862bb01bc10485023af0 326 Gene3D G3DSA:3.40.50.2020 155 299 9.7E-110 T 12-10-2018 TL08_03695 59e11ac146a5862bb01bc10485023af0 326 SUPERFAMILY SSF53271 77 314 2.26E-60 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_03695 59e11ac146a5862bb01bc10485023af0 326 Gene3D G3DSA:3.40.50.2020 15 310 9.7E-110 T 12-10-2018 TL08_03695 59e11ac146a5862bb01bc10485023af0 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 1.9E-43 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TL08_03695 59e11ac146a5862bb01bc10485023af0 326 SMART SM01400 12 128 5.9E-68 T 12-10-2018 TL08_03695 59e11ac146a5862bb01bc10485023af0 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 322 4.1E-113 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TL08_03695 59e11ac146a5862bb01bc10485023af0 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 3.9E-20 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TL08_03695 59e11ac146a5862bb01bc10485023af0 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TL08_17685 ae53cc36633f56be8c296f20f0a6b71c 247 SMART SM00563 38 152 4.4E-33 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_17685 ae53cc36633f56be8c296f20f0a6b71c 247 Pfam PF01553 Acyltransferase 24 149 3.0E-28 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_17685 ae53cc36633f56be8c296f20f0a6b71c 247 SUPERFAMILY SSF69593 19 206 5.36E-35 T 12-10-2018 TL08_08565 4120aafba3ec311a6c413886e4920ede 443 Pfam PF05977 Transmembrane secretion effector 14 410 3.9E-24 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_08565 4120aafba3ec311a6c413886e4920ede 443 SUPERFAMILY SSF103473 13 409 1.2E-36 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_08565 4120aafba3ec311a6c413886e4920ede 443 Gene3D G3DSA:1.20.1250.20 11 403 7.1E-29 T 12-10-2018 TL08_14465 43e419328a6fdbdbb1d1212e19d7ba41 503 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 402 1.0E-57 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_14465 43e419328a6fdbdbb1d1212e19d7ba41 503 PIRSF PIRSF002741 434 477 77.0 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_14465 43e419328a6fdbdbb1d1212e19d7ba41 503 PIRSF PIRSF002741 5 419 2.9E-47 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_14465 43e419328a6fdbdbb1d1212e19d7ba41 503 SUPERFAMILY SSF53850 33 494 8.55E-78 T 12-10-2018 TL08_14465 43e419328a6fdbdbb1d1212e19d7ba41 503 Gene3D G3DSA:3.40.190.10 26 277 1.0E-34 T 12-10-2018 TL08_14465 43e419328a6fdbdbb1d1212e19d7ba41 503 Gene3D G3DSA:3.10.105.10 278 473 2.6E-31 T 12-10-2018 TL08_17535 1b217a5d70c6c3a50fad0f440b33ba87 357 Gene3D G3DSA:2.40.420.20 252 326 3.3E-12 T 12-10-2018 TL08_14640 b55d969855828fcefc517c6c02cfc351 939 Gene3D G3DSA:1.10.10.10 831 902 7.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_14640 b55d969855828fcefc517c6c02cfc351 939 Gene3D G3DSA:3.40.50.300 1 151 5.5E-6 T 12-10-2018 TL08_14640 b55d969855828fcefc517c6c02cfc351 939 SMART SM00421 836 893 2.8E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14640 b55d969855828fcefc517c6c02cfc351 939 SUPERFAMILY SSF46894 831 893 3.16E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_14640 b55d969855828fcefc517c6c02cfc351 939 Pfam PF00196 Bacterial regulatory proteins, luxR family 839 892 5.0E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14640 b55d969855828fcefc517c6c02cfc351 939 Gene3D G3DSA:1.25.40.10 504 817 1.3E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_14640 b55d969855828fcefc517c6c02cfc351 939 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 869 881 9.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14640 b55d969855828fcefc517c6c02cfc351 939 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 839 853 9.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14640 b55d969855828fcefc517c6c02cfc351 939 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 853 869 9.5E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_14640 b55d969855828fcefc517c6c02cfc351 939 SUPERFAMILY SSF52540 3 193 1.11E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_14640 b55d969855828fcefc517c6c02cfc351 939 Pfam PF13191 AAA ATPase domain 2 151 5.9E-17 T 12-10-2018 TL08_02570 1a6e8ed422b4379da3a17d4e82769f42 303 PIRSF PIRSF037834 34 303 1.8E-87 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 TL08_02570 1a6e8ed422b4379da3a17d4e82769f42 303 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 52 303 4.5E-70 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 TL08_02570 1a6e8ed422b4379da3a17d4e82769f42 303 SUPERFAMILY SSF47240 44 297 6.76E-63 T 12-10-2018 IPR009078 Ferritin-like superfamily TL08_02570 1a6e8ed422b4379da3a17d4e82769f42 303 Pfam PF05138 Phenylacetic acid catabolic protein 38 303 2.1E-75 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 TL08_02570 1a6e8ed422b4379da3a17d4e82769f42 303 Gene3D G3DSA:1.20.1260.10 34 303 6.7E-95 T 12-10-2018 IPR012347 Ferritin-like TL08_25175 67b61f98f08eb211afb5ec571904e97c 232 Pfam PF10801 Protein of unknown function (DUF2537) 146 225 3.3E-21 T 12-10-2018 IPR024244 Protein of unknown function DUF2537 TL08_25175 67b61f98f08eb211afb5ec571904e97c 232 ProDom PD053583 TRANSMEMBRANE MEMBRANE PRECURSOR SIGNAL MB0906 RV0882/MT0905 144 228 7.0E-7 T 12-10-2018 IPR024244 Protein of unknown function DUF2537 TL08_14960 907c60fe2334582a1583e8a3bb690313 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 69 339 2.8E-52 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TL08_14960 907c60fe2334582a1583e8a3bb690313 341 PIRSF PIRSF017082 11 341 2.0E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TL08_14960 907c60fe2334582a1583e8a3bb690313 341 Gene3D G3DSA:3.40.190.150 49 332 2.8E-80 T 12-10-2018 TL08_14960 907c60fe2334582a1583e8a3bb690313 341 SUPERFAMILY SSF53850 133 303 1.45E-10 T 12-10-2018 TL08_14960 907c60fe2334582a1583e8a3bb690313 341 Gene3D G3DSA:3.40.190.10 146 268 2.8E-80 T 12-10-2018 TL08_20245 50e0886d12b072e45bfa92d45519de94 247 Pfam PF13490 Putative zinc-finger 3 36 9.0E-7 T 12-10-2018 IPR027383 Putative zinc-finger TL08_23405 6a843b5969ee1c8b30e2e39118b73000 383 Gene3D G3DSA:3.40.50.2000 192 375 2.3E-35 T 12-10-2018 TL08_23405 6a843b5969ee1c8b30e2e39118b73000 383 SUPERFAMILY SSF53756 15 375 2.04E-66 T 12-10-2018 TL08_23405 6a843b5969ee1c8b30e2e39118b73000 383 Gene3D G3DSA:3.40.50.2000 8 191 2.3E-19 T 12-10-2018 TL08_23405 6a843b5969ee1c8b30e2e39118b73000 383 Pfam PF00534 Glycosyl transferases group 1 196 354 5.8E-20 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_23405 6a843b5969ee1c8b30e2e39118b73000 383 Pfam PF13439 Glycosyltransferase Family 4 20 180 7.5E-21 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_21530 063974e58589e8c96f8715ce5a87a818 165 Pfam PF04073 Aminoacyl-tRNA editing domain 30 149 1.8E-24 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TL08_21530 063974e58589e8c96f8715ce5a87a818 165 Gene3D G3DSA:3.90.960.10 3 160 3.1E-36 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TL08_21530 063974e58589e8c96f8715ce5a87a818 165 SUPERFAMILY SSF55826 9 157 1.57E-30 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TL08_09415 18d947edeff28f0262c55dfc8821a993 252 SUPERFAMILY SSF53335 19 200 9.73E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_09415 18d947edeff28f0262c55dfc8821a993 252 Gene3D G3DSA:3.40.50.150 1 248 4.6E-45 T 12-10-2018 TL08_09415 18d947edeff28f0262c55dfc8821a993 252 Pfam PF13489 Methyltransferase domain 9 191 1.6E-16 T 12-10-2018 TL08_12620 acf24596305368ce11871b3f3252143b 169 Gene3D G3DSA:3.10.129.10 17 166 2.4E-43 T 12-10-2018 TL08_12620 acf24596305368ce11871b3f3252143b 169 SUPERFAMILY SSF54637 20 163 1.01E-33 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_12620 acf24596305368ce11871b3f3252143b 169 Pfam PF01575 MaoC like domain 29 132 1.1E-19 T 12-10-2018 IPR002539 MaoC-like dehydratase domain TL08_22550 69c087228db4bf0ae19819383d260ee4 182 SUPERFAMILY SSF55729 1 156 3.49E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_22550 69c087228db4bf0ae19819383d260ee4 182 Gene3D G3DSA:3.40.630.30 2 165 7.8E-32 T 12-10-2018 TL08_22550 69c087228db4bf0ae19819383d260ee4 182 Pfam PF00583 Acetyltransferase (GNAT) family 28 138 2.9E-11 T 12-10-2018 IPR000182 GNAT domain TL08_17165 aef96b485407d41566db429fe5599247 814 Gene3D G3DSA:1.50.10.10 311 714 9.1E-146 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TL08_17165 aef96b485407d41566db429fe5599247 814 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 318 729 6.5E-139 T 12-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 TL08_17165 aef96b485407d41566db429fe5599247 814 SUPERFAMILY SSF48208 268 769 1.59E-103 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_17165 aef96b485407d41566db429fe5599247 814 Gene3D G3DSA:2.60.420.10 715 783 7.5E-11 T 12-10-2018 TL08_17165 aef96b485407d41566db429fe5599247 814 SUPERFAMILY SSF74650 3 264 5.96E-66 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TL08_17165 aef96b485407d41566db429fe5599247 814 PIRSF PIRSF036289 1 797 1.3E-205 T 12-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase TL08_17165 aef96b485407d41566db429fe5599247 814 Gene3D G3DSA:2.70.98.40 1 265 3.9E-78 T 12-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily TL08_17165 aef96b485407d41566db429fe5599247 814 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 9 263 1.1E-67 T 12-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 TL08_20715 07403152d2bbf29d7432fe2f09d27e4d 333 Gene3D G3DSA:3.40.190.10 153 302 2.0E-78 T 12-10-2018 TL08_20715 07403152d2bbf29d7432fe2f09d27e4d 333 Gene3D G3DSA:3.40.190.10 44 152 2.0E-78 T 12-10-2018 TL08_20715 07403152d2bbf29d7432fe2f09d27e4d 333 Pfam PF01547 Bacterial extracellular solute-binding protein 53 256 8.6E-31 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_20715 07403152d2bbf29d7432fe2f09d27e4d 333 SUPERFAMILY SSF53850 30 305 2.12E-48 T 12-10-2018 TL08_04985 c8ba02ceab88eadd9dff36e37210d222 231 Gene3D G3DSA:3.40.109.10 1 222 1.8E-54 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_04985 c8ba02ceab88eadd9dff36e37210d222 231 Pfam PF00881 Nitroreductase family 15 201 4.6E-25 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TL08_04985 c8ba02ceab88eadd9dff36e37210d222 231 SUPERFAMILY SSF55469 6 225 4.32E-34 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_18315 eaa6a7d0460a6b0fafbfe580d73202d5 394 Gene3D G3DSA:3.40.50.10350 10 373 1.0E-123 T 12-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold TL08_18315 eaa6a7d0460a6b0fafbfe580d73202d5 394 PIRSF PIRSF006078 10 389 6.1E-107 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TL08_18315 eaa6a7d0460a6b0fafbfe580d73202d5 394 Pfam PF02595 Glycerate kinase family 12 384 9.9E-132 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TL08_18315 eaa6a7d0460a6b0fafbfe580d73202d5 394 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 11 384 9.6E-134 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TL08_18315 eaa6a7d0460a6b0fafbfe580d73202d5 394 SUPERFAMILY SSF110738 11 386 2.75E-115 T 12-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 TL08_18315 eaa6a7d0460a6b0fafbfe580d73202d5 394 Gene3D G3DSA:3.90.1510.10 51 287 1.0E-123 T 12-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 TL08_10885 c0417840b40026f9d8b1079837cfce94 321 SMART SM00327 89 286 2.0E-23 T 12-10-2018 IPR002035 von Willebrand factor, type A TL08_10885 c0417840b40026f9d8b1079837cfce94 321 SUPERFAMILY SSF53300 86 283 5.7E-29 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_10885 c0417840b40026f9d8b1079837cfce94 321 Pfam PF07584 Aerotolerance regulator N-terminal 6 79 2.7E-8 T 12-10-2018 IPR024163 Aerotolerance regulator, N-terminal TL08_10885 c0417840b40026f9d8b1079837cfce94 321 Gene3D G3DSA:3.40.50.410 80 284 4.5E-44 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TL08_10885 c0417840b40026f9d8b1079837cfce94 321 Pfam PF13519 von Willebrand factor type A domain 92 205 8.2E-20 T 12-10-2018 IPR002035 von Willebrand factor, type A TL08_22010 8969f7c9e50514b0da7d39163a1008bb 275 Gene3D G3DSA:3.40.50.1980 15 126 5.6E-20 T 12-10-2018 TL08_22010 8969f7c9e50514b0da7d39163a1008bb 275 Gene3D G3DSA:3.40.50.1980 137 264 1.2E-6 T 12-10-2018 TL08_22010 8969f7c9e50514b0da7d39163a1008bb 275 SUPERFAMILY SSF53807 16 260 6.28E-29 T 12-10-2018 TL08_13330 20185e312751bd5cd6dbaee7e7cb7b7c 577 SUPERFAMILY SSF52091 443 549 2.75E-12 T 12-10-2018 IPR036513 STAS domain superfamily TL08_13330 20185e312751bd5cd6dbaee7e7cb7b7c 577 Pfam PF01740 STAS domain 441 545 1.5E-14 T 12-10-2018 IPR002645 STAS domain TL08_13330 20185e312751bd5cd6dbaee7e7cb7b7c 577 Pfam PF00916 Sulfate permease family 34 393 9.4E-71 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 TL08_13330 20185e312751bd5cd6dbaee7e7cb7b7c 577 Gene3D G3DSA:3.30.750.24 428 557 6.5E-24 T 12-10-2018 IPR036513 STAS domain superfamily TL08_07180 8e027040cf1a853f3b83922288c4f731 86 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 84 18.881 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TL08_07180 8e027040cf1a853f3b83922288c4f731 86 Pfam PF02416 mttA/Hcf106 family 4 49 1.2E-13 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TL08_04945 637072f93a30d8bae3948b4077397098 664 SUPERFAMILY SSF46785 529 646 8.42E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_04945 637072f93a30d8bae3948b4077397098 664 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 2.9E-6 T 12-10-2018 TL08_04945 637072f93a30d8bae3948b4077397098 664 PRINTS PR01036 Tetracycline resistance protein TetB signature 205 223 2.9E-6 T 12-10-2018 TL08_04945 637072f93a30d8bae3948b4077397098 664 PRINTS PR01036 Tetracycline resistance protein TetB signature 404 423 2.9E-6 T 12-10-2018 TL08_04945 637072f93a30d8bae3948b4077397098 664 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 2.9E-6 T 12-10-2018 TL08_04945 637072f93a30d8bae3948b4077397098 664 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 2.9E-6 T 12-10-2018 TL08_04945 637072f93a30d8bae3948b4077397098 664 Pfam PF07690 Major Facilitator Superfamily 21 413 1.2E-55 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_04945 637072f93a30d8bae3948b4077397098 664 Gene3D G3DSA:1.20.1720.10 18 225 1.9E-55 T 12-10-2018 TL08_04945 637072f93a30d8bae3948b4077397098 664 Gene3D G3DSA:1.10.10.10 502 650 6.1E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_04945 637072f93a30d8bae3948b4077397098 664 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 494 8.9E-84 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TL08_04945 637072f93a30d8bae3948b4077397098 664 SUPERFAMILY SSF103473 10 495 1.74E-73 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_25440 6f9c37fd6e5baf5a0dfc4634aade01d1 304 SUPERFAMILY SSF51430 27 303 7.73E-62 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_25440 6f9c37fd6e5baf5a0dfc4634aade01d1 304 Pfam PF00248 Aldo/keto reductase family 36 303 5.2E-48 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_25440 6f9c37fd6e5baf5a0dfc4634aade01d1 304 Gene3D G3DSA:3.20.20.100 29 304 1.5E-66 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_25440 6f9c37fd6e5baf5a0dfc4634aade01d1 304 PRINTS PR00069 Aldo-keto reductase signature 66 90 3.1E-12 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_25440 6f9c37fd6e5baf5a0dfc4634aade01d1 304 PRINTS PR00069 Aldo-keto reductase signature 239 263 3.1E-12 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_25440 6f9c37fd6e5baf5a0dfc4634aade01d1 304 PRINTS PR00069 Aldo-keto reductase signature 168 185 3.1E-12 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TL08_24420 5d98f8549972f2b4091fe946dcf054c0 383 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 79 381 1.2E-48 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TL08_24420 5d98f8549972f2b4091fe946dcf054c0 383 Gene3D G3DSA:3.40.50.2300 181 377 5.7E-88 T 12-10-2018 TL08_24420 5d98f8549972f2b4091fe946dcf054c0 383 Gene3D G3DSA:3.40.50.2300 75 344 5.7E-88 T 12-10-2018 TL08_24420 5d98f8549972f2b4091fe946dcf054c0 383 SUPERFAMILY SSF53822 108 305 1.84E-7 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_23170 a761ebe8e54bd08fc6a38127be4d6fbd 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.365 T 12-10-2018 IPR003482 Transcription factor WhiB TL08_23170 a761ebe8e54bd08fc6a38127be4d6fbd 84 Pfam PF02467 Transcription factor WhiB 3 71 1.4E-26 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TL08_05335 fe5298348b47c4d7660211d2a1403e96 325 Pfam PF13280 WYL domain 147 318 6.0E-29 T 12-10-2018 IPR026881 WYL domain TL08_05335 fe5298348b47c4d7660211d2a1403e96 325 Gene3D G3DSA:1.10.10.10 1 62 7.8E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05335 fe5298348b47c4d7660211d2a1403e96 325 PIRSF PIRSF016838 1 325 2.4E-17 T 12-10-2018 IPR028349 Protein PafC TL08_05335 fe5298348b47c4d7660211d2a1403e96 325 SUPERFAMILY SSF46785 2 57 1.41E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05335 fe5298348b47c4d7660211d2a1403e96 325 Pfam PF08279 HTH domain 8 57 2.9E-14 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TL08_12870 459f455fbef12cef6f1b6fc65a99e2fb 336 Gene3D G3DSA:3.40.50.2300 54 312 3.2E-44 T 12-10-2018 TL08_12870 459f455fbef12cef6f1b6fc65a99e2fb 336 Pfam PF13407 Periplasmic binding protein domain 52 305 1.5E-27 T 12-10-2018 IPR025997 Periplasmic binding protein TL08_12870 459f455fbef12cef6f1b6fc65a99e2fb 336 SUPERFAMILY SSF53822 48 322 7.79E-43 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_12870 459f455fbef12cef6f1b6fc65a99e2fb 336 Gene3D G3DSA:3.40.50.2300 151 319 3.2E-44 T 12-10-2018 TL08_11155 5d930507ec6ce930fe5f40e11eea06d5 421 Pfam PF13416 Bacterial extracellular solute-binding protein 50 350 1.9E-34 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_11155 5d930507ec6ce930fe5f40e11eea06d5 421 Gene3D G3DSA:3.40.190.10 142 412 1.5E-123 T 12-10-2018 TL08_11155 5d930507ec6ce930fe5f40e11eea06d5 421 SUPERFAMILY SSF53850 28 419 3.67E-58 T 12-10-2018 TL08_11155 5d930507ec6ce930fe5f40e11eea06d5 421 Gene3D G3DSA:3.40.190.10 31 367 1.5E-123 T 12-10-2018 TL08_00240 0867ab4399f3b4866d062918b986c149 237 Gene3D G3DSA:2.60.40.2230 29 185 9.1E-51 T 12-10-2018 IPR038507 YcnI-like superfamily TL08_00240 0867ab4399f3b4866d062918b986c149 237 Pfam PF07987 Domain of unkown function (DUF1775) 31 171 3.0E-39 T 12-10-2018 IPR012533 YcnI-like TL08_24020 870e36a867a2993dae2da69811517681 531 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 9 527 1.3E-228 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TL08_24020 870e36a867a2993dae2da69811517681 531 SUPERFAMILY SSF51703 9 525 8.44E-202 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TL08_24020 870e36a867a2993dae2da69811517681 531 Pfam PF01642 Methylmalonyl-CoA mutase 9 523 1.5E-218 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TL08_24020 870e36a867a2993dae2da69811517681 531 Gene3D G3DSA:3.20.20.240 4 531 1.2E-229 T 12-10-2018 TL08_06380 20ebf289bb98d24d54522b6e19ef4677 150 Pfam PF12680 SnoaL-like domain 10 119 7.1E-16 T 12-10-2018 IPR037401 SnoaL-like domain TL08_06380 20ebf289bb98d24d54522b6e19ef4677 150 SUPERFAMILY SSF54427 9 132 4.5E-21 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_06380 20ebf289bb98d24d54522b6e19ef4677 150 Gene3D G3DSA:3.10.450.50 7 136 2.7E-24 T 12-10-2018 TL08_19240 431d7412cf46a29eca9e2fc4df8c533f 256 Pfam PF13560 Helix-turn-helix domain 1 48 1.1E-6 T 12-10-2018 TL08_19240 431d7412cf46a29eca9e2fc4df8c533f 256 Gene3D G3DSA:1.10.260.40 1 48 8.6E-7 T 12-10-2018 TL08_19240 431d7412cf46a29eca9e2fc4df8c533f 256 SUPERFAMILY SSF47413 1 46 7.24E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_13380 fa9976d9c3f3a4a9f19768face4524fa 425 SMART SM00710 229 251 2600.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_13380 fa9976d9c3f3a4a9f19768face4524fa 425 SMART SM00710 176 198 1900.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_13380 fa9976d9c3f3a4a9f19768face4524fa 425 SMART SM00710 386 414 1000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_13380 fa9976d9c3f3a4a9f19768face4524fa 425 SMART SM00710 334 356 86.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_13380 fa9976d9c3f3a4a9f19768face4524fa 425 Gene3D G3DSA:2.160.20.10 105 425 6.6E-8 T 12-10-2018 IPR012334 Pectin lyase fold TL08_13380 fa9976d9c3f3a4a9f19768face4524fa 425 SUPERFAMILY SSF51126 108 425 6.28E-15 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_04370 0b6c8247446566237e0b6bd60d2df5bc 99 SUPERFAMILY SSF55248 1 94 5.1E-27 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TL08_04370 0b6c8247446566237e0b6bd60d2df5bc 99 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 2 93 20.314 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TL08_04370 0b6c8247446566237e0b6bd60d2df5bc 99 Gene3D G3DSA:3.30.1360.20 4 99 1.1E-27 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TL08_04370 0b6c8247446566237e0b6bd60d2df5bc 99 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 91 3.4E-26 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TL08_17315 fd9bf6c4daf25f1b154145781758eeac 230 Gene3D G3DSA:3.40.50.720 1 193 4.7E-49 T 12-10-2018 TL08_17315 fd9bf6c4daf25f1b154145781758eeac 230 SUPERFAMILY SSF51735 4 192 1.69E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_17315 fd9bf6c4daf25f1b154145781758eeac 230 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 90 2.3E-17 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TL08_04865 48c963cfc2642dfcc1a9f8ea22d30a8f 460 SUPERFAMILY SSF63411 26 245 7.14E-28 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TL08_04865 48c963cfc2642dfcc1a9f8ea22d30a8f 460 Pfam PF05193 Peptidase M16 inactive domain 202 375 1.4E-15 T 12-10-2018 IPR007863 Peptidase M16, C-terminal TL08_04865 48c963cfc2642dfcc1a9f8ea22d30a8f 460 SUPERFAMILY SSF63411 264 456 9.33E-33 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TL08_04865 48c963cfc2642dfcc1a9f8ea22d30a8f 460 Gene3D G3DSA:3.30.830.10 43 247 1.2E-30 T 12-10-2018 TL08_04865 48c963cfc2642dfcc1a9f8ea22d30a8f 460 Gene3D G3DSA:3.30.830.10 256 447 1.0E-40 T 12-10-2018 TL08_11330 c176ecea02c2027880928f7b5228a76f 599 Gene3D G3DSA:1.10.510.40 376 578 2.1E-48 T 12-10-2018 TL08_11330 c176ecea02c2027880928f7b5228a76f 599 Pfam PF06276 Ferric iron reductase FhuF-like transporter 409 560 5.6E-31 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain TL08_11330 c176ecea02c2027880928f7b5228a76f 599 Pfam PF04183 IucA / IucC family 140 387 6.5E-74 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 TL08_11330 c176ecea02c2027880928f7b5228a76f 599 Gene3D G3DSA:1.10.274.90 3 127 3.0E-20 T 12-10-2018 TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 Pfam PF01145 SPFH domain / Band 7 family 24 195 1.6E-33 T 12-10-2018 IPR001107 Band 7 domain TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 Gene3D G3DSA:3.30.479.30 48 180 8.7E-45 T 12-10-2018 TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 ProSitePatterns PS01270 Band 7 protein family signature. 134 162 - T 12-10-2018 IPR018080 Band 7/stomatin-like, conserved site TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 PRINTS PR00721 Stomatin signature 173 194 5.3E-36 T 12-10-2018 IPR001972 Stomatin family GO:0016020 TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 PRINTS PR00721 Stomatin signature 75 96 5.3E-36 T 12-10-2018 IPR001972 Stomatin family GO:0016020 TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 PRINTS PR00721 Stomatin signature 130 153 5.3E-36 T 12-10-2018 IPR001972 Stomatin family GO:0016020 TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 PRINTS PR00721 Stomatin signature 110 127 5.3E-36 T 12-10-2018 IPR001972 Stomatin family GO:0016020 TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 PRINTS PR00721 Stomatin signature 27 49 5.3E-36 T 12-10-2018 IPR001972 Stomatin family GO:0016020 TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 PRINTS PR00721 Stomatin signature 154 172 5.3E-36 T 12-10-2018 IPR001972 Stomatin family GO:0016020 TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 SUPERFAMILY SSF117892 51 185 1.7E-41 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily TL08_10925 0242a69adf6d09812cd78eaa5dd97023 394 SMART SM00244 20 178 1.4E-57 T 12-10-2018 IPR001107 Band 7 domain TL08_25580 dd9d8c1b577743d212ae83722c874280 238 SUPERFAMILY SSF51197 13 214 1.03E-43 T 12-10-2018 TL08_25580 dd9d8c1b577743d212ae83722c874280 238 Gene3D G3DSA:2.60.120.590 9 217 6.8E-53 T 12-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily TL08_25580 dd9d8c1b577743d212ae83722c874280 238 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 15 213 2.6E-49 T 12-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like TL08_01600 8bb5c27079e5b5c70d1295210f11901f 160 Gene3D G3DSA:2.60.40.2880 65 155 1.9E-14 T 12-10-2018 IPR038468 Transport accessory protein MmpS, soluble domain superfamily TL08_01600 8bb5c27079e5b5c70d1295210f11901f 160 Pfam PF05423 Mycobacterium membrane protein 16 152 1.7E-11 T 12-10-2018 IPR008693 Transport accessory protein MmpS TL08_06770 077e6cbef1302332fb7917cde22a9631 113 Pfam PF00355 Rieske [2Fe-2S] domain 5 88 2.8E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TL08_06770 077e6cbef1302332fb7917cde22a9631 113 SUPERFAMILY SSF50022 1 102 7.46E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_06770 077e6cbef1302332fb7917cde22a9631 113 Gene3D G3DSA:2.102.10.10 2 111 5.5E-33 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TL08_10360 cfb3ecc1ad04ed955410d8dee831c0d0 357 Gene3D G3DSA:3.90.79.10 191 333 7.9E-24 T 12-10-2018 TL08_10360 cfb3ecc1ad04ed955410d8dee831c0d0 357 Gene3D G3DSA:1.20.1440.20 23 190 3.3E-5 T 12-10-2018 IPR023353 LemA-like domain superfamily TL08_10360 cfb3ecc1ad04ed955410d8dee831c0d0 357 SUPERFAMILY SSF55811 197 327 1.19E-19 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_10360 cfb3ecc1ad04ed955410d8dee831c0d0 357 ProSitePatterns PS00893 Nudix box signature. 235 256 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_10360 cfb3ecc1ad04ed955410d8dee831c0d0 357 Pfam PF00293 NUDIX domain 199 328 3.5E-18 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_13145 643fc5730533b9cff454b637db162583 265 Gene3D G3DSA:3.40.50.150 2 264 7.9E-102 T 12-10-2018 TL08_13145 643fc5730533b9cff454b637db162583 265 Pfam PF04672 S-adenosyl methyltransferase 8 264 2.1E-86 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_13145 643fc5730533b9cff454b637db162583 265 SUPERFAMILY SSF53335 12 248 1.62E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_13145 643fc5730533b9cff454b637db162583 265 PIRSF PIRSF017393 2 265 3.8E-91 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type TL08_20055 1eab741b4cfd10c066eba582d4aadf6f 405 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 3 331 1.4E-86 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 TL08_20055 1eab741b4cfd10c066eba582d4aadf6f 405 Pfam PF09344 CT1975-like protein 3 365 1.3E-110 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 TL08_26105 d8ca08f5508a2d74b2d4f3bcdb37b2a9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_26105 d8ca08f5508a2d74b2d4f3bcdb37b2a9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_26105 d8ca08f5508a2d74b2d4f3bcdb37b2a9 200 Gene3D G3DSA:1.10.357.10 4 198 3.6E-35 T 12-10-2018 TL08_26105 d8ca08f5508a2d74b2d4f3bcdb37b2a9 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 2.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_26105 d8ca08f5508a2d74b2d4f3bcdb37b2a9 200 SUPERFAMILY SSF46689 4 80 1.95E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_05700 6b99be99afe203e2ba7c985871c0a7fa 243 Pfam PF00881 Nitroreductase family 19 218 1.4E-17 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TL08_05700 6b99be99afe203e2ba7c985871c0a7fa 243 Gene3D G3DSA:3.40.109.10 7 233 8.0E-34 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_05700 6b99be99afe203e2ba7c985871c0a7fa 243 SUPERFAMILY SSF55469 11 242 2.62E-28 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_02010 2d71b4b07252161a2d361d29cdb35c55 383 Gene3D G3DSA:1.10.4080.10 23 379 1.1E-54 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TL08_02010 2d71b4b07252161a2d361d29cdb35c55 383 SUPERFAMILY SSF101478 24 366 1.44E-48 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TL08_02010 2d71b4b07252161a2d361d29cdb35c55 383 Pfam PF03747 ADP-ribosylglycohydrolase 32 347 1.4E-54 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 TL08_05395 d92e6ebc9e93829b901137a75e94b848 286 SMART SM00530 11 83 5.0E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_05395 d92e6ebc9e93829b901137a75e94b848 286 Pfam PF13560 Helix-turn-helix domain 8 86 2.9E-13 T 12-10-2018 TL08_05395 d92e6ebc9e93829b901137a75e94b848 286 Gene3D G3DSA:1.10.260.40 25 92 5.4E-8 T 12-10-2018 TL08_05395 d92e6ebc9e93829b901137a75e94b848 286 SUPERFAMILY SSF47413 23 81 1.24E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_22035 a10b4e4321353a6970b2d059d57a5e74 329 SUPERFAMILY SSF54001 197 310 1.23E-35 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TL08_22035 a10b4e4321353a6970b2d059d57a5e74 329 Pfam PF00877 NlpC/P60 family 215 304 7.2E-20 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain TL08_22035 a10b4e4321353a6970b2d059d57a5e74 329 Gene3D G3DSA:3.90.1720.10 186 316 3.7E-42 T 12-10-2018 TL08_04590 ba73df5a99a9fbe66236ea0de95ce69d 259 Pfam PF14011 EspG family 13 253 3.7E-52 T 12-10-2018 IPR025734 EspG family TL08_23370 eb01d9aaa6cf1f8f20d5fe238c371f20 104 Pfam PF02467 Transcription factor WhiB 36 99 2.4E-27 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TL08_23370 eb01d9aaa6cf1f8f20d5fe238c371f20 104 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 26 104 19.382 T 12-10-2018 IPR003482 Transcription factor WhiB TL08_09555 09832b8c8efad157a51ad6b7618353c7 273 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 6.1E-15 T 12-10-2018 IPR019933 DivIVA domain TL08_09555 09832b8c8efad157a51ad6b7618353c7 273 Pfam PF05103 DivIVA protein 3 65 4.2E-13 T 12-10-2018 IPR007793 DivIVA family TL08_04935 5e0fb2f637afdf1f5e46abebbfd2fe95 987 Pfam PF03699 Uncharacterised protein family (UPF0182) 12 811 3.8E-279 T 12-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 TL08_04935 5e0fb2f637afdf1f5e46abebbfd2fe95 987 Hamap MF_01600 UPF0182 protein . 3 888 18.392 T 12-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 TL08_20695 6fe2cb0f510330241cd6ca862ec04492 329 Pfam PF00544 Pectate lyase 106 265 2.2E-34 T 12-10-2018 IPR002022 Pectate lyase TL08_20695 6fe2cb0f510330241cd6ca862ec04492 329 SUPERFAMILY SSF51126 52 328 6.62E-70 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_20695 6fe2cb0f510330241cd6ca862ec04492 329 Gene3D G3DSA:2.160.20.10 49 329 4.8E-89 T 12-10-2018 IPR012334 Pectin lyase fold TL08_20695 6fe2cb0f510330241cd6ca862ec04492 329 SMART SM00656 67 271 6.1E-40 T 12-10-2018 IPR002022 Pectate lyase TL08_20695 6fe2cb0f510330241cd6ca862ec04492 329 SMART SM00710 232 254 1300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_20695 6fe2cb0f510330241cd6ca862ec04492 329 SMART SM00710 130 152 29.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_20695 6fe2cb0f510330241cd6ca862ec04492 329 SMART SM00710 255 294 7100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_20695 6fe2cb0f510330241cd6ca862ec04492 329 SMART SM00710 154 176 1400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TL08_03890 5caa038ba0396d7459b0d4fb483e0073 361 SUPERFAMILY SSF51735 165 322 2.49E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_03890 5caa038ba0396d7459b0d4fb483e0073 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 42 150 1.1E-25 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TL08_03890 5caa038ba0396d7459b0d4fb483e0073 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 78 92 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TL08_03890 5caa038ba0396d7459b0d4fb483e0073 361 Gene3D G3DSA:3.40.50.720 173 305 3.9E-75 T 12-10-2018 TL08_03890 5caa038ba0396d7459b0d4fb483e0073 361 SUPERFAMILY SSF50129 18 195 1.34E-40 T 12-10-2018 IPR011032 GroES-like superfamily TL08_03890 5caa038ba0396d7459b0d4fb483e0073 361 Pfam PF00107 Zinc-binding dehydrogenase 198 319 2.3E-15 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_03890 5caa038ba0396d7459b0d4fb483e0073 361 Gene3D G3DSA:3.90.180.10 27 345 3.9E-75 T 12-10-2018 TL08_06910 87c7caee23e08f06d8a6ae022fa69890 298 Gene3D G3DSA:3.30.450.180 111 283 5.1E-18 T 12-10-2018 TL08_06910 87c7caee23e08f06d8a6ae022fa69890 298 SUPERFAMILY SSF47413 36 84 1.13E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_06910 87c7caee23e08f06d8a6ae022fa69890 298 Pfam PF13560 Helix-turn-helix domain 11 90 5.4E-19 T 12-10-2018 TL08_06910 87c7caee23e08f06d8a6ae022fa69890 298 Gene3D G3DSA:1.10.260.40 30 104 7.8E-10 T 12-10-2018 TL08_06910 87c7caee23e08f06d8a6ae022fa69890 298 SMART SM00530 15 87 1.2E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_24050 00df88c8aaa304258ae806248570178e 202 SUPERFAMILY SSF48498 86 195 3.56E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_24050 00df88c8aaa304258ae806248570178e 202 Gene3D G3DSA:1.10.357.10 2 197 3.2E-41 T 12-10-2018 TL08_24050 00df88c8aaa304258ae806248570178e 202 SUPERFAMILY SSF46689 1 87 1.26E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_24050 00df88c8aaa304258ae806248570178e 202 Pfam PF13305 WHG domain 90 173 3.4E-14 T 12-10-2018 IPR025996 WHG domain TL08_24050 00df88c8aaa304258ae806248570178e 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_12120 fc003562684a8732c823acf58a7c3b7e 190 SUPERFAMILY SSF81995 13 87 7.06E-5 T 12-10-2018 TL08_12120 fc003562684a8732c823acf58a7c3b7e 190 Pfam PF14230 Domain of unknown function (DUF4333) 106 183 4.7E-25 T 12-10-2018 IPR025637 Domain of unknown function DUF4333 TL08_14205 6d07e42d7b6479d6960c1a0194a0a453 315 SUPERFAMILY SSF56112 52 308 3.35E-25 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_14205 6d07e42d7b6479d6960c1a0194a0a453 315 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 44 295 8.9E-64 T 12-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 TL08_24160 efa47fb9ab1faa7216e9777bc4d78e67 793 Pfam PF03176 MMPL family 504 719 3.3E-26 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TL08_24160 efa47fb9ab1faa7216e9777bc4d78e67 793 Pfam PF03176 MMPL family 43 374 2.8E-47 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TL08_24160 efa47fb9ab1faa7216e9777bc4d78e67 793 Gene3D G3DSA:1.20.1640.10 147 337 8.1E-11 T 12-10-2018 TL08_24160 efa47fb9ab1faa7216e9777bc4d78e67 793 SUPERFAMILY SSF82866 503 712 1.28E-22 T 12-10-2018 TL08_24160 efa47fb9ab1faa7216e9777bc4d78e67 793 SUPERFAMILY SSF82866 109 333 6.15E-32 T 12-10-2018 TL08_14175 1bd008b64b1e695b4f07f73692858791 296 Gene3D G3DSA:3.40.50.1820 2 295 1.3E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14175 1bd008b64b1e695b4f07f73692858791 296 SUPERFAMILY SSF53474 6 292 6.0E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_14175 1bd008b64b1e695b4f07f73692858791 296 Pfam PF00561 alpha/beta hydrolase fold 22 278 2.6E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_15670 cdbe707f1a03fc0cf74dc6fbcda906d1 308 Gene3D G3DSA:3.90.25.10 160 292 1.6E-69 T 12-10-2018 TL08_15670 cdbe707f1a03fc0cf74dc6fbcda906d1 308 Pfam PF05368 NmrA-like family 5 241 3.2E-47 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 TL08_15670 cdbe707f1a03fc0cf74dc6fbcda906d1 308 SUPERFAMILY SSF51735 5 292 1.35E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_15670 cdbe707f1a03fc0cf74dc6fbcda906d1 308 Gene3D G3DSA:3.40.50.720 5 286 1.6E-69 T 12-10-2018 TL08_03550 534d05718bec78d734fb4f73a55707b3 1133 Pfam PF13569 Domain of unknown function (DUF4132) 874 1055 1.0E-40 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_18135 480e8ca69143de16e8c80c5c7dba00cc 290 Pfam PF12697 Alpha/beta hydrolase family 16 276 8.2E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_18135 480e8ca69143de16e8c80c5c7dba00cc 290 SUPERFAMILY SSF53474 6 287 1.94E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18135 480e8ca69143de16e8c80c5c7dba00cc 290 Gene3D G3DSA:3.40.50.1820 12 290 3.2E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18485 f64216314289e5d30e5cf0ff9f1d1c24 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 3.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_18485 f64216314289e5d30e5cf0ff9f1d1c24 204 Gene3D G3DSA:3.40.50.12740 1 204 9.5E-22 T 12-10-2018 TL08_18485 f64216314289e5d30e5cf0ff9f1d1c24 204 SUPERFAMILY SSF46894 129 204 1.9E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_18485 f64216314289e5d30e5cf0ff9f1d1c24 204 SMART SM00421 141 198 6.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_13095 c53dcbe20118de2ddddfb85f2804a1f8 144 SUPERFAMILY SSF52980 13 133 7.51E-34 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TL08_13095 c53dcbe20118de2ddddfb85f2804a1f8 144 Gene3D G3DSA:3.40.960.10 27 142 2.1E-39 T 12-10-2018 TL08_13095 c53dcbe20118de2ddddfb85f2804a1f8 144 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 16 126 3.9E-35 T 12-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 TL08_13095 c53dcbe20118de2ddddfb85f2804a1f8 144 Pfam PF03852 DNA mismatch endonuclease Vsr 17 79 1.7E-17 T 12-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 TL08_00930 179b08be1f80fbc883731031ff1ddfe3 255 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 240 1.3E-36 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 TL08_00930 179b08be1f80fbc883731031ff1ddfe3 255 SUPERFAMILY SSF51621 6 252 3.14E-64 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TL08_00930 179b08be1f80fbc883731031ff1ddfe3 255 Gene3D G3DSA:3.20.20.60 2 255 1.8E-71 T 12-10-2018 TL08_11535 e096c18ecc2f3682c58030195a23da81 176 Pfam PF12802 MarR family 38 97 1.7E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_11535 e096c18ecc2f3682c58030195a23da81 176 SUPERFAMILY SSF46785 25 123 1.08E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_11535 e096c18ecc2f3682c58030195a23da81 176 Gene3D G3DSA:1.10.10.10 13 103 6.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_16590 92906d1d5f1f9ab74c4ab120e7d75b43 150 SUPERFAMILY SSF52799 38 141 1.7E-21 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like TL08_16590 92906d1d5f1f9ab74c4ab120e7d75b43 150 Pfam PF00102 Protein-tyrosine phosphatase 49 118 4.8E-5 T 12-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 TL08_16590 92906d1d5f1f9ab74c4ab120e7d75b43 150 Gene3D G3DSA:3.90.190.10 38 149 3.8E-19 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like TL08_22785 36d73a3fb746eed160335cf4f919c4f5 180 Pfam PF07681 DoxX 25 106 4.2E-16 T 12-10-2018 IPR032808 DoxX family TL08_10390 3c8d56c87cb36225df92361047fd4d6f 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 4 97 4.2E-14 T 12-10-2018 IPR008407 Branched-chain amino acid transport, AzlD TL08_20375 701f68404bd951047c4a444797f2122f 140 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 20 135 3.4E-31 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III TL08_15090 f5ecd5f2045d67e6ee706253f3e3f22e 259 SUPERFAMILY SSF46955 4 105 3.66E-20 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TL08_15090 f5ecd5f2045d67e6ee706253f3e3f22e 259 Pfam PF00376 MerR family regulatory protein 4 41 6.6E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_15090 f5ecd5f2045d67e6ee706253f3e3f22e 259 SMART SM00422 3 72 1.8E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TL08_08340 b96e40205933813305a6dd4e94081138 87 Pfam PF11238 Protein of unknown function (DUF3039) 26 81 5.1E-28 T 12-10-2018 IPR021400 Protein of unknown function DUF3039 TL08_11710 c84c74f40bc7d967ebd1646a1c113e4a 669 SUPERFAMILY SSF55486 267 343 1.94E-5 T 12-10-2018 TL08_11710 c84c74f40bc7d967ebd1646a1c113e4a 669 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 94 350 2.4E-34 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 TL08_20435 4b88e4368ef5e3a8f1c7515836614cc4 283 Pfam PF04248 Domain of unknown function (DUF427) 182 273 9.6E-26 T 12-10-2018 IPR007361 Domain of unknown function DUF427 TL08_20435 4b88e4368ef5e3a8f1c7515836614cc4 283 Pfam PF04248 Domain of unknown function (DUF427) 57 148 3.8E-30 T 12-10-2018 IPR007361 Domain of unknown function DUF427 TL08_20435 4b88e4368ef5e3a8f1c7515836614cc4 283 Gene3D G3DSA:2.170.150.40 166 281 8.6E-31 T 12-10-2018 TL08_20435 4b88e4368ef5e3a8f1c7515836614cc4 283 Gene3D G3DSA:2.170.150.40 44 152 1.4E-32 T 12-10-2018 TL08_13765 073ab262b05164ff54f06a94b0fe6fc1 163 Pfam PF12802 MarR family 44 103 3.0E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13765 073ab262b05164ff54f06a94b0fe6fc1 163 SUPERFAMILY SSF46785 28 154 3.72E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_13765 073ab262b05164ff54f06a94b0fe6fc1 163 SMART SM00347 38 141 4.4E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_13765 073ab262b05164ff54f06a94b0fe6fc1 163 Gene3D G3DSA:1.10.10.10 16 159 1.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06710 c86534488098b59d5370667b0679c948 92 Gene3D G3DSA:1.10.1200.10 2 81 2.8E-6 T 12-10-2018 IPR036736 ACP-like superfamily TL08_06710 c86534488098b59d5370667b0679c948 92 SUPERFAMILY SSF47336 15 74 2.56E-6 T 12-10-2018 IPR036736 ACP-like superfamily TL08_18320 2634d82760c1ab9cd40e44fcaad6e076 524 Pfam PF00939 Sodium:sulfate symporter transmembrane region 60 502 1.6E-25 T 12-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 TL08_26710 df9a15d0e90bcaa369350654bbf3ec6f 555 Pfam PF03806 AbgT putative transporter family 289 552 2.0E-83 T 12-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 TL08_26710 df9a15d0e90bcaa369350654bbf3ec6f 555 Pfam PF03806 AbgT putative transporter family 21 254 1.1E-60 T 12-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 TL08_05025 bdea159af0b93cd97fc6b97ccf0da962 89 SUPERFAMILY SSF47336 2 83 9.42E-16 T 12-10-2018 IPR036736 ACP-like superfamily TL08_05025 bdea159af0b93cd97fc6b97ccf0da962 89 Gene3D G3DSA:1.10.1200.10 3 86 2.2E-18 T 12-10-2018 IPR036736 ACP-like superfamily TL08_05025 bdea159af0b93cd97fc6b97ccf0da962 89 Pfam PF00550 Phosphopantetheine attachment site 19 76 1.2E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_08635 7f7e0690b40023102c7882d0533877e0 397 Gene3D G3DSA:3.40.980.20 222 391 1.5E-20 T 12-10-2018 TL08_08635 7f7e0690b40023102c7882d0533877e0 397 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 231 383 8.3E-22 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain TL08_08635 7f7e0690b40023102c7882d0533877e0 397 Gene3D G3DSA:3.40.50.10840 4 221 2.6E-56 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily TL08_08635 7f7e0690b40023102c7882d0533877e0 397 SUPERFAMILY SSF142764 5 388 1.2E-84 T 12-10-2018 TL08_08635 7f7e0690b40023102c7882d0533877e0 397 Pfam PF07005 Putative sugar-binding N-terminal domain 5 215 2.5E-48 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain TL08_09895 09a3b47c8e3b2cf17d8495fa1d2a4f84 446 Pfam PF01757 Acyltransferase family 47 402 9.6E-17 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_12105 553afdd8204932d7c09bbbc0b59824da 144 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 100 19.699 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TL08_12105 553afdd8204932d7c09bbbc0b59824da 144 Pfam PF02416 mttA/Hcf106 family 4 53 9.6E-14 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TL08_17820 d355da3f086706d5b9c5f7faf8bcebbb 285 Pfam PF09335 SNARE associated Golgi protein 45 163 7.4E-21 T 12-10-2018 IPR032816 SNARE associated Golgi protein TL08_16100 fb5eb2ab843258f2f81b5c5eceba3c5b 198 SUPERFAMILY SSF46689 1 72 3.26E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16100 fb5eb2ab843258f2f81b5c5eceba3c5b 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 2.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16100 fb5eb2ab843258f2f81b5c5eceba3c5b 198 Gene3D G3DSA:1.10.357.10 1 171 5.2E-31 T 12-10-2018 TL08_19580 f1f795e773087306c6ebdc183f4a61da 187 SUPERFAMILY SSF53697 2 184 1.5E-44 T 12-10-2018 TL08_19580 f1f795e773087306c6ebdc183f4a61da 187 Gene3D G3DSA:3.40.50.10490 1 185 7.8E-62 T 12-10-2018 TL08_19580 f1f795e773087306c6ebdc183f4a61da 187 Pfam PF13580 SIS domain 9 140 8.3E-27 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TL08_19605 a3f08cbe2dded0674fb016ad264931f0 294 Pfam PF12697 Alpha/beta hydrolase family 34 266 4.8E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_19605 a3f08cbe2dded0674fb016ad264931f0 294 Gene3D G3DSA:3.40.50.1820 11 287 1.1E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_19605 a3f08cbe2dded0674fb016ad264931f0 294 SUPERFAMILY SSF53474 12 281 4.22E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13235 7be3e430978cd1b1e6acab356bbb0232 219 Pfam PF04493 Endonuclease V 27 213 2.8E-63 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TL08_13235 7be3e430978cd1b1e6acab356bbb0232 219 Gene3D G3DSA:3.30.2170.10 2 219 1.7E-75 T 12-10-2018 TL08_13235 7be3e430978cd1b1e6acab356bbb0232 219 Hamap MF_00801 Endonuclease V [nfi]. 13 218 28.703 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TL08_11270 bec75645953c5064cb38e92ed67da7a5 407 Gene3D G3DSA:1.20.1250.20 220 395 7.1E-17 T 12-10-2018 TL08_11270 bec75645953c5064cb38e92ed67da7a5 407 SUPERFAMILY SSF103473 9 403 2.62E-33 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_11270 bec75645953c5064cb38e92ed67da7a5 407 Gene3D G3DSA:1.20.1250.20 12 194 8.2E-15 T 12-10-2018 TL08_11270 bec75645953c5064cb38e92ed67da7a5 407 Pfam PF07690 Major Facilitator Superfamily 245 391 2.0E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_11270 bec75645953c5064cb38e92ed67da7a5 407 Pfam PF07690 Major Facilitator Superfamily 17 197 1.5E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_02895 7c56caa6d8552dc8030c383624d85ce4 186 SUPERFAMILY SSF160369 1 169 1.44E-49 T 12-10-2018 TL08_02895 7c56caa6d8552dc8030c383624d85ce4 186 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.223 T 12-10-2018 IPR022973 Ribosomal protein L10 TL08_02895 7c56caa6d8552dc8030c383624d85ce4 186 Pfam PF00466 Ribosomal protein L10 1 98 5.8E-25 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TL08_02895 7c56caa6d8552dc8030c383624d85ce4 186 Gene3D G3DSA:3.30.70.1730 1 170 5.1E-37 T 12-10-2018 TL08_25885 dbd26e30e391d8dd8f22c2b42a28ac1e 258 SMART SM00382 29 223 3.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_25885 dbd26e30e391d8dd8f22c2b42a28ac1e 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 1.6E-114 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 TL08_25885 dbd26e30e391d8dd8f22c2b42a28ac1e 258 Gene3D G3DSA:3.40.50.300 2 256 6.5E-63 T 12-10-2018 TL08_25885 dbd26e30e391d8dd8f22c2b42a28ac1e 258 SUPERFAMILY SSF52540 5 244 1.82E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_25885 dbd26e30e391d8dd8f22c2b42a28ac1e 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_25885 dbd26e30e391d8dd8f22c2b42a28ac1e 258 Pfam PF00005 ABC transporter 21 176 2.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_12695 05e3175c9df61c0b09a7c1857606c571 66 Pfam PF04149 Domain of unknown function (DUF397) 8 61 3.4E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_19380 6cf00243eb120256aa1396e24c47c477 278 Gene3D G3DSA:1.10.3720.10 3 268 4.0E-57 T 12-10-2018 IPR035906 MetI-like superfamily TL08_19380 6cf00243eb120256aa1396e24c47c477 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 263 6.2E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_19380 6cf00243eb120256aa1396e24c47c477 278 SUPERFAMILY SSF161098 10 277 7.33E-64 T 12-10-2018 IPR035906 MetI-like superfamily TL08_06370 f5f5db010fc26d78250f1ec9f0b83860 246 SMART SM00382 38 224 1.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_06370 f5f5db010fc26d78250f1ec9f0b83860 246 SUPERFAMILY SSF52540 10 228 7.32E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06370 f5f5db010fc26d78250f1ec9f0b83860 246 Gene3D G3DSA:3.40.50.300 7 245 4.8E-70 T 12-10-2018 TL08_06370 f5f5db010fc26d78250f1ec9f0b83860 246 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_06370 f5f5db010fc26d78250f1ec9f0b83860 246 Pfam PF00005 ABC transporter 29 175 1.1E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23195 8d25cf3e04330567764edada1b19f751 206 Gene3D G3DSA:3.40.50.1820 24 198 3.9E-17 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_23195 8d25cf3e04330567764edada1b19f751 206 SUPERFAMILY SSF53474 3 200 3.6E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_26130 0320ce49297a5c4b514bd4a54545f486 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 7.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_26130 0320ce49297a5c4b514bd4a54545f486 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 8 19 7.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_26130 0320ce49297a5c4b514bd4a54545f486 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 7.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_26130 0320ce49297a5c4b514bd4a54545f486 205 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 7.5E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_26130 0320ce49297a5c4b514bd4a54545f486 205 Pfam PF00702 haloacid dehalogenase-like hydrolase 91 182 9.3E-9 T 12-10-2018 TL08_26130 0320ce49297a5c4b514bd4a54545f486 205 SUPERFAMILY SSF56784 8 191 2.14E-28 T 12-10-2018 IPR036412 HAD-like superfamily TL08_26130 0320ce49297a5c4b514bd4a54545f486 205 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 87 185 1.5E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TL08_26130 0320ce49297a5c4b514bd4a54545f486 205 Gene3D G3DSA:3.40.50.1000 7 202 3.9E-31 T 12-10-2018 IPR023214 HAD superfamily TL08_16320 77a3a067afc0a21f3d95f31c860285d0 437 SUPERFAMILY SSF56601 4 331 1.48E-56 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_16320 77a3a067afc0a21f3d95f31c860285d0 437 Pfam PF00144 Beta-lactamase 9 323 2.5E-46 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_16320 77a3a067afc0a21f3d95f31c860285d0 437 Gene3D G3DSA:3.40.710.10 3 332 7.6E-60 T 12-10-2018 TL08_12715 a57a74a55d680e08d813e4ecd5acbc71 380 Pfam PF01008 Initiation factor 2 subunit family 84 365 4.8E-47 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TL08_12715 a57a74a55d680e08d813e4ecd5acbc71 380 SUPERFAMILY SSF100950 36 373 1.59E-73 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_12715 a57a74a55d680e08d813e4ecd5acbc71 380 Gene3D G3DSA:3.40.50.10470 174 365 5.4E-70 T 12-10-2018 TL08_12715 a57a74a55d680e08d813e4ecd5acbc71 380 Gene3D G3DSA:1.20.120.420 65 173 5.4E-70 T 12-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TL08_22405 62fc0462208ca79dc57d5a947f79c4bc 144 Gene3D G3DSA:3.10.450.30 49 144 1.7E-37 T 12-10-2018 TL08_22405 62fc0462208ca79dc57d5a947f79c4bc 144 SUPERFAMILY SSF53933 53 141 9.96E-37 T 12-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 TL08_22405 62fc0462208ca79dc57d5a947f79c4bc 144 Pfam PF00545 ribonuclease 60 138 5.6E-28 T 12-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 TL08_21250 3cd0e11da2e704ad96088f3adb64b2b4 423 Pfam PF01966 HD domain 68 213 5.0E-18 T 12-10-2018 IPR006674 HD domain TL08_21250 3cd0e11da2e704ad96088f3adb64b2b4 423 SMART SM00471 64 223 8.2E-12 T 12-10-2018 IPR003607 HD/PDEase domain TL08_21250 3cd0e11da2e704ad96088f3adb64b2b4 423 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 31 415 1.3E-82 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 TL08_21250 3cd0e11da2e704ad96088f3adb64b2b4 423 Gene3D G3DSA:1.10.3210.10 5 416 1.8E-92 T 12-10-2018 TL08_21250 3cd0e11da2e704ad96088f3adb64b2b4 423 SUPERFAMILY SSF109604 30 234 7.75E-57 T 12-10-2018 TL08_21250 3cd0e11da2e704ad96088f3adb64b2b4 423 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 14 415 31.816 T 12-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 TL08_21250 3cd0e11da2e704ad96088f3adb64b2b4 423 Pfam PF13286 Phosphohydrolase-associated domain 322 413 1.2E-20 T 12-10-2018 IPR026875 Phosphohydrolase-associated domain TL08_08315 7ef60a68c4cab3195ea63e8c29602ed2 220 Pfam PF01553 Acyltransferase 21 150 1.5E-25 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_08315 7ef60a68c4cab3195ea63e8c29602ed2 220 SUPERFAMILY SSF69593 7 217 9.29E-50 T 12-10-2018 TL08_08315 7ef60a68c4cab3195ea63e8c29602ed2 220 SMART SM00563 34 153 6.6E-34 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_02665 1be284587b4060fd4b6db41e5fc03a34 542 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 9 518 5.2E-171 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02665 1be284587b4060fd4b6db41e5fc03a34 542 Pfam PF00361 Proton-conducting membrane transporter 133 426 1.3E-61 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02665 1be284587b4060fd4b6db41e5fc03a34 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 246 270 7.3E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02665 1be284587b4060fd4b6db41e5fc03a34 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 7.3E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02665 1be284587b4060fd4b6db41e5fc03a34 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 169 193 7.3E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02665 1be284587b4060fd4b6db41e5fc03a34 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 334 353 7.3E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_02665 1be284587b4060fd4b6db41e5fc03a34 542 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 386 412 7.3E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_21770 72ef845ef8cfeb0682dee0263cc03e31 137 SUPERFAMILY SSF52172 12 129 1.57E-6 T 12-10-2018 IPR011006 CheY-like superfamily TL08_21770 72ef845ef8cfeb0682dee0263cc03e31 137 Gene3D G3DSA:3.40.50.2300 2 133 5.7E-7 T 12-10-2018 TL08_00515 6f6a235272f220350d3e2437e181eff4 68 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 6 33 5.1E-6 T 12-10-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB TL08_05830 ad689471fb7f4855c48df43277c151ae 1110 Pfam PF13569 Domain of unknown function (DUF4132) 846 1024 2.9E-51 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_11615 d9644c3bdeacd113898bb9a96755ac38 339 SUPERFAMILY SSF142338 3 310 4.05E-81 T 12-10-2018 TL08_11615 d9644c3bdeacd113898bb9a96755ac38 339 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 5 309 9.3E-86 T 12-10-2018 IPR010119 Gluconeogenesis factor TL08_11615 d9644c3bdeacd113898bb9a96755ac38 339 Hamap MF_00973 Gluconeogenesis factor. 1 315 31.027 T 12-10-2018 IPR010119 Gluconeogenesis factor TL08_11615 d9644c3bdeacd113898bb9a96755ac38 339 Gene3D G3DSA:3.40.50.12300 2 315 8.2E-93 T 12-10-2018 IPR038136 Gluconeogenesis factor superfamily TL08_11615 d9644c3bdeacd113898bb9a96755ac38 339 Pfam PF01933 Uncharacterised protein family UPF0052 5 269 6.9E-69 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 TL08_10240 bd8ca92f463ab73f319362fe021412de 305 Gene3D G3DSA:3.40.630.30 143 299 2.7E-18 T 12-10-2018 TL08_10240 bd8ca92f463ab73f319362fe021412de 305 Pfam PF00583 Acetyltransferase (GNAT) family 192 278 3.6E-6 T 12-10-2018 IPR000182 GNAT domain TL08_10240 bd8ca92f463ab73f319362fe021412de 305 SUPERFAMILY SSF55729 130 294 1.22E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_03995 99ed16a7ec5e31b7ee2e813876746265 386 SUPERFAMILY SSF53335 8 226 2.05E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_03995 99ed16a7ec5e31b7ee2e813876746265 386 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 166 181 - T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TL08_03995 99ed16a7ec5e31b7ee2e813876746265 386 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 13 224 4.3E-27 T 12-10-2018 TL08_03995 99ed16a7ec5e31b7ee2e813876746265 386 Gene3D G3DSA:3.40.50.150 7 246 2.5E-54 T 12-10-2018 TL08_14940 cec601eeb1d7fcdeee85e71e8db675c8 627 SUPERFAMILY SSF69318 169 568 8.5E-14 T 12-10-2018 TL08_14940 cec601eeb1d7fcdeee85e71e8db675c8 627 Gene3D G3DSA:2.60.40.10 46 148 6.4E-22 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_12575 ea699b6d77de844227bb82c9a30e42a1 282 Gene3D G3DSA:3.40.50.300 6 266 8.9E-57 T 12-10-2018 TL08_12575 ea699b6d77de844227bb82c9a30e42a1 282 SUPERFAMILY SSF52540 18 266 2.09E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_12575 ea699b6d77de844227bb82c9a30e42a1 282 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 246 266 2.0E-10 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TL08_12575 ea699b6d77de844227bb82c9a30e42a1 282 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_12575 ea699b6d77de844227bb82c9a30e42a1 282 SMART SM00382 44 244 9.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_12575 ea699b6d77de844227bb82c9a30e42a1 282 Pfam PF00005 ABC transporter 35 195 3.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_02195 e9a61d7239a4bfd19cf58ee52afe1831 102 Pfam PF10724 Protein of unknown function (DUF2516) 9 99 3.7E-30 T 12-10-2018 IPR019662 Protein of unknown function DUF2516 TL08_25420 bd54d9421f1d3261e3a34b3980d7a298 211 SUPERFAMILY SSF51219 4 207 4.71E-27 T 12-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily TL08_25420 bd54d9421f1d3261e3a34b3980d7a298 211 Gene3D G3DSA:3.60.160.10 1 211 1.5E-30 T 12-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily TL08_25420 bd54d9421f1d3261e3a34b3980d7a298 211 Pfam PF01987 Mitochondrial biogenesis AIM24 11 204 3.1E-24 T 12-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 TL08_18190 d6cf90f9f411d286172994994195925f 165 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 50 4.8E-21 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TL08_18190 d6cf90f9f411d286172994994195925f 165 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 59 142 1.9E-33 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 TL08_18190 d6cf90f9f411d286172994994195925f 165 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 2 145 9.4E-54 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TL08_18190 d6cf90f9f411d286172994994195925f 165 ProSitePatterns PS00938 Initiation factor 3 signature. 33 46 - T 12-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 TL08_18190 d6cf90f9f411d286172994994195925f 165 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 145 23.455 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TL08_18190 d6cf90f9f411d286172994994195925f 165 SUPERFAMILY SSF54364 1 53 9.55E-20 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TL08_18190 d6cf90f9f411d286172994994195925f 165 Gene3D G3DSA:3.10.20.80 1 50 2.1E-21 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TL08_18190 d6cf90f9f411d286172994994195925f 165 SUPERFAMILY SSF55200 60 144 7.06E-31 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TL08_18190 d6cf90f9f411d286172994994195925f 165 Gene3D G3DSA:3.30.110.10 51 146 5.4E-33 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TL08_05850 6b1feb4e4c0d155bfeae5456752c2299 254 SUPERFAMILY SSF102588 4 202 4.32E-26 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_05850 6b1feb4e4c0d155bfeae5456752c2299 254 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 142 1.9E-15 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TL08_05850 6b1feb4e4c0d155bfeae5456752c2299 254 Gene3D G3DSA:3.40.50.10320 2 225 8.2E-38 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TL08_00135 65bb6dba2401687df775ad45ae660685 482 Pfam PF01098 Cell cycle protein 90 455 8.5E-86 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TL08_26485 9d52218bdff3849b81593f6a8adbc1af 370 SUPERFAMILY SSF52374 25 338 1.42E-9 T 12-10-2018 TL08_21485 a84bc7fb8628f5e7fe82a241f06e491e 216 SUPERFAMILY SSF50800 3 211 3.87E-48 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TL08_21485 a84bc7fb8628f5e7fe82a241f06e491e 216 Gene3D G3DSA:2.40.33.20 1 215 1.6E-58 T 12-10-2018 TL08_21485 a84bc7fb8628f5e7fe82a241f06e491e 216 Pfam PF03473 MOSC domain 53 161 3.4E-15 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 TL08_18835 6f4542f4d3156e3f55583bd38a1d10d0 141 Pfam PF04075 F420H(2)-dependent quinone reductase 18 135 6.9E-38 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_18835 6f4542f4d3156e3f55583bd38a1d10d0 141 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 27 137 1.8E-33 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_18835 6f4542f4d3156e3f55583bd38a1d10d0 141 Gene3D G3DSA:2.30.110.10 4 140 3.4E-53 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_18835 6f4542f4d3156e3f55583bd38a1d10d0 141 SUPERFAMILY SSF50475 45 139 1.57E-5 T 12-10-2018 TL08_19560 a21cb6af1d639e6eb415ec867f8e8d45 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 25 322 3.4E-47 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_19560 a21cb6af1d639e6eb415ec867f8e8d45 338 SUPERFAMILY SSF51735 23 329 2.53E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_19560 a21cb6af1d639e6eb415ec867f8e8d45 338 Gene3D G3DSA:3.40.50.720 23 313 1.3E-93 T 12-10-2018 TL08_19560 a21cb6af1d639e6eb415ec867f8e8d45 338 Gene3D G3DSA:3.90.25.10 205 326 1.3E-93 T 12-10-2018 TL08_20090 d0269b18503be6043dfa5d83d04e558e 622 SUPERFAMILY SSF69318 138 569 1.22E-13 T 12-10-2018 TL08_20090 d0269b18503be6043dfa5d83d04e558e 622 Gene3D G3DSA:2.60.40.10 41 131 2.0E-29 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_20510 23dd155405d07b6a9eb5f3a7864dbf54 249 Pfam PF12483 E3 Ubiquitin ligase 109 205 5.7E-6 T 12-10-2018 IPR022170 E3 Ubiquitin ligase, GIDE-type GO:0004842|GO:0006996|GO:0016567 MetaCyc: PWY-7511|Reactome: R-HSA-5689880 TL08_11810 613586ee51aed55ce8134ca9a54a7906 397 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 114 384 1.1E-73 T 12-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 TL08_11810 613586ee51aed55ce8134ca9a54a7906 397 SUPERFAMILY SSF101960 41 392 6.93E-87 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TL08_11810 613586ee51aed55ce8134ca9a54a7906 397 Pfam PF01458 Uncharacterized protein family (UPF0051) 147 367 3.8E-71 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TL08_14075 f980143d5ab97dd36a79c2d69923fa5c 178 Pfam PF03358 NADPH-dependent FMN reductase 6 133 3.4E-31 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TL08_14075 f980143d5ab97dd36a79c2d69923fa5c 178 SUPERFAMILY SSF52218 6 163 4.69E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_14075 f980143d5ab97dd36a79c2d69923fa5c 178 Gene3D G3DSA:3.40.50.360 1 176 2.0E-43 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_15900 593aa4203489f859dd038d082dc7bc32 277 Pfam PF08241 Methyltransferase domain 68 165 3.4E-23 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_15900 593aa4203489f859dd038d082dc7bc32 277 SMART SM00828 Methyltransferase in polyketide synthase (PKS) enzymes. 51 277 0.0023 T 12-10-2018 IPR020803 Polyketide synthase, methyltransferase domain TL08_15900 593aa4203489f859dd038d082dc7bc32 277 Gene3D G3DSA:3.40.50.150 1 273 1.9E-63 T 12-10-2018 TL08_15900 593aa4203489f859dd038d082dc7bc32 277 SUPERFAMILY SSF53335 9 265 5.27E-53 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_23285 59e35150fdefd4a2b287b3072dd93c27 609 SMART SM00909 226 314 1.8E-7 T 12-10-2018 IPR019606 GerMN domain TL08_23285 59e35150fdefd4a2b287b3072dd93c27 609 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 343 608 2.5E-38 T 12-10-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal TL08_23285 59e35150fdefd4a2b287b3072dd93c27 609 Pfam PF10646 Sporulation and spore germination 200 308 2.8E-9 T 12-10-2018 IPR019606 GerMN domain TL08_04555 c113349022cb7b4eda536b0ecbd6c7f7 262 Pfam PF14011 EspG family 15 254 2.2E-54 T 12-10-2018 IPR025734 EspG family TL08_06790 54df41089c97034a098ce7ef4ba29bb5 182 Gene3D G3DSA:3.40.50.1950 2 181 4.0E-18 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TL08_06790 54df41089c97034a098ce7ef4ba29bb5 182 SUPERFAMILY SSF52507 3 175 1.44E-18 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TL08_06790 54df41089c97034a098ce7ef4ba29bb5 182 Pfam PF02441 Flavoprotein 5 150 9.6E-14 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TL08_25445 2a1a5e9d67430962d03bf0e347ca3fb4 221 SUPERFAMILY SSF46894 151 221 1.05E-8 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TL08_25445 2a1a5e9d67430962d03bf0e347ca3fb4 221 SMART SM00421 159 216 1.8E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TL08_25445 2a1a5e9d67430962d03bf0e347ca3fb4 221 Gene3D G3DSA:1.10.10.10 64 221 1.9E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_00750 d4b46d8ed17b2ec8cacfdc93e66a9000 426 Gene3D G3DSA:3.60.10.10 60 422 1.3E-19 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_00750 d4b46d8ed17b2ec8cacfdc93e66a9000 426 SUPERFAMILY SSF56219 60 421 3.02E-20 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_00750 d4b46d8ed17b2ec8cacfdc93e66a9000 426 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 64 414 2.0E-28 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TL08_13725 d9f6d985b9c0f02d9056bc70d1b11e21 254 Pfam PF00975 Thioesterase domain 22 244 3.3E-56 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_13725 d9f6d985b9c0f02d9056bc70d1b11e21 254 Gene3D G3DSA:3.40.50.1820 2 248 4.6E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13725 d9f6d985b9c0f02d9056bc70d1b11e21 254 SMART SM00824 Thioesterase 24 246 2.3E-6 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 TL08_13725 d9f6d985b9c0f02d9056bc70d1b11e21 254 SUPERFAMILY SSF53474 6 246 1.94E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_17460 b6cb1e0697a0a26a31c48755805953a4 655 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 7 613 7.9E-173 T 12-10-2018 IPR011749 Conserved hypothetical protein CHP02243 TL08_17460 b6cb1e0697a0a26a31c48755805953a4 655 Pfam PF04865 Baseplate J-like protein 398 562 1.7E-9 T 12-10-2018 IPR006949 Baseplate protein J-like TL08_07600 13cacc5b0a34ae97b80f153a599876b3 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 262 5.2E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_07600 13cacc5b0a34ae97b80f153a599876b3 334 Gene3D G3DSA:1.10.3720.10 85 325 9.1E-55 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07600 13cacc5b0a34ae97b80f153a599876b3 334 SUPERFAMILY SSF161098 88 315 1.44E-48 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23770 52a3a4b54619ed8002a8188947d83c25 275 Pfam PF14011 EspG family 16 258 2.8E-64 T 12-10-2018 IPR025734 EspG family TL08_06385 2103667b5f05e9301e24d8a7904c2acb 179 Pfam PF01638 HxlR-like helix-turn-helix 28 114 2.2E-22 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_06385 2103667b5f05e9301e24d8a7904c2acb 179 Gene3D G3DSA:1.10.10.10 10 167 2.6E-52 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_06385 2103667b5f05e9301e24d8a7904c2acb 179 SUPERFAMILY SSF46785 14 154 6.62E-41 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_02600 c55a11adb7da081a6330bbd795973500 441 Gene3D G3DSA:3.50.50.60 20 425 6.9E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_02600 c55a11adb7da081a6330bbd795973500 441 Pfam PF01494 FAD binding domain 22 339 7.0E-20 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_02600 c55a11adb7da081a6330bbd795973500 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 23 45 1.7E-14 T 12-10-2018 TL08_02600 c55a11adb7da081a6330bbd795973500 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 173 188 1.7E-14 T 12-10-2018 TL08_02600 c55a11adb7da081a6330bbd795973500 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 1.7E-14 T 12-10-2018 TL08_02600 c55a11adb7da081a6330bbd795973500 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 326 1.7E-14 T 12-10-2018 TL08_02600 c55a11adb7da081a6330bbd795973500 441 SUPERFAMILY SSF51905 23 419 1.33E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_02600 c55a11adb7da081a6330bbd795973500 441 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 24 346 4.4E-73 T 12-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 TL08_15035 909603ff16ddf02a5ea7c63f167f5b75 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 296 8.7E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_15035 909603ff16ddf02a5ea7c63f167f5b75 314 SUPERFAMILY SSF161098 34 313 5.42E-56 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15035 909603ff16ddf02a5ea7c63f167f5b75 314 Gene3D G3DSA:1.10.3720.10 28 304 2.5E-54 T 12-10-2018 IPR035906 MetI-like superfamily TL08_05690 ccfa750b4ecd21d011bbffe8bf2e4e4c 354 SUPERFAMILY SSF101790 280 331 1.8E-6 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TL08_05690 ccfa750b4ecd21d011bbffe8bf2e4e4c 354 Gene3D G3DSA:3.30.1360.120 2 344 1.5E-55 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TL08_05690 ccfa750b4ecd21d011bbffe8bf2e4e4c 354 SUPERFAMILY SSF103025 12 265 5.02E-46 T 12-10-2018 TL08_05690 ccfa750b4ecd21d011bbffe8bf2e4e4c 354 PIRSF PIRSF006487 1 347 4.8E-41 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TL08_05690 ccfa750b4ecd21d011bbffe8bf2e4e4c 354 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 247 6.2E-34 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TL08_05690 ccfa750b4ecd21d011bbffe8bf2e4e4c 354 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 255 330 2.0E-10 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TL08_26100 2fbdab402c516c7ae461a74f2e5a057e 409 SUPERFAMILY SSF103473 2 390 7.85E-41 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_26100 2fbdab402c516c7ae461a74f2e5a057e 409 Pfam PF00083 Sugar (and other) transporter 254 363 5.0E-6 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TL08_26100 2fbdab402c516c7ae461a74f2e5a057e 409 Pfam PF07690 Major Facilitator Superfamily 10 243 1.2E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_26100 2fbdab402c516c7ae461a74f2e5a057e 409 PRINTS PR01035 Tetracycline resistance protein signature 136 158 4.7E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_26100 2fbdab402c516c7ae461a74f2e5a057e 409 PRINTS PR01035 Tetracycline resistance protein signature 14 30 4.7E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_26100 2fbdab402c516c7ae461a74f2e5a057e 409 PRINTS PR01035 Tetracycline resistance protein signature 280 301 4.7E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TL08_26100 2fbdab402c516c7ae461a74f2e5a057e 409 Gene3D G3DSA:1.20.1250.20 1 187 5.3E-19 T 12-10-2018 TL08_26100 2fbdab402c516c7ae461a74f2e5a057e 409 Gene3D G3DSA:1.20.1250.20 207 395 7.9E-16 T 12-10-2018 TL08_15960 dea6df6480d681c1979a96aba5a85d59 98 Gene3D G3DSA:1.10.443.10 5 82 5.9E-16 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TL08_15960 dea6df6480d681c1979a96aba5a85d59 98 Pfam PF00589 Phage integrase family 15 69 5.9E-12 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TL08_15960 dea6df6480d681c1979a96aba5a85d59 98 SUPERFAMILY SSF56349 14 76 6.77E-17 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 Gene3D G3DSA:3.40.50.1820 2 391 3.8E-132 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 SUPERFAMILY SSF53474 4 386 4.42E-94 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 Pfam PF06441 Epoxide hydrolase N terminus 8 120 4.6E-32 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 PRINTS PR00412 Epoxide hydrolase signature 330 346 1.9E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 PRINTS PR00412 Epoxide hydrolase signature 111 129 1.9E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 PRINTS PR00412 Epoxide hydrolase signature 362 384 1.9E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 PRINTS PR00412 Epoxide hydrolase signature 182 195 1.9E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 PRINTS PR00412 Epoxide hydrolase signature 137 152 1.9E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 PRINTS PR00412 Epoxide hydrolase signature 196 209 1.9E-13 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_06925 75498f71fbd3174b79f158ed1f194a55 393 PIRSF PIRSF001112 3 390 1.0E-111 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 TL08_25145 ac477bc3be4a03979fd44ead9f21a106 334 Pfam PF11268 Protein of unknown function (DUF3071) 1 169 2.0E-60 T 12-10-2018 IPR021421 Protein of unknown function DUF3071 TL08_14170 4090d8e6e1d2e5e6e92f2dd1b8f6d6e7 228 SUPERFAMILY SSF51261 51 220 7.32E-48 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_14170 4090d8e6e1d2e5e6e92f2dd1b8f6d6e7 228 Pfam PF01551 Peptidase family M23 122 216 4.3E-30 T 12-10-2018 IPR016047 Peptidase M23 TL08_14170 4090d8e6e1d2e5e6e92f2dd1b8f6d6e7 228 Gene3D G3DSA:2.70.70.10 69 223 2.1E-42 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_04600 9a6a26a25896b52f52b9798aee3dfb3e 306 Gene3D G3DSA:3.90.226.10 47 248 3.2E-68 T 12-10-2018 TL08_04600 9a6a26a25896b52f52b9798aee3dfb3e 306 SUPERFAMILY SSF52096 47 305 6.1E-81 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_04600 9a6a26a25896b52f52b9798aee3dfb3e 306 Gene3D G3DSA:1.10.12.10 249 306 1.5E-19 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TL08_04600 9a6a26a25896b52f52b9798aee3dfb3e 306 Pfam PF00378 Enoyl-CoA hydratase/isomerase 54 304 2.9E-62 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TL08_07120 d4bfb207180a93a4ade3fcb3433257a9 202 SUPERFAMILY SSF52218 1 160 7.76E-39 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_07120 d4bfb207180a93a4ade3fcb3433257a9 202 Pfam PF03358 NADPH-dependent FMN reductase 2 147 1.1E-36 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TL08_07120 d4bfb207180a93a4ade3fcb3433257a9 202 Gene3D G3DSA:3.40.50.360 1 202 4.3E-47 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 Gene3D G3DSA:1.10.630.10 104 495 3.6E-112 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00385 P450 superfamily signature 333 350 8.8E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00385 P450 superfamily signature 435 444 8.8E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00385 P450 superfamily signature 444 455 8.8E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 SUPERFAMILY SSF48264 110 495 2.75E-80 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00359 B-class P450 signature 386 413 6.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00359 B-class P450 signature 444 455 6.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00359 B-class P450 signature 286 308 6.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00359 B-class P450 signature 368 379 6.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00359 B-class P450 signature 248 263 6.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00359 B-class P450 signature 414 429 6.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00359 B-class P450 signature 435 444 6.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00359 B-class P450 signature 184 195 6.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 PRINTS PR00359 B-class P450 signature 231 247 6.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_16025 d2f27247ae5924f1d556b496d2451d63 495 Pfam PF00067 Cytochrome P450 297 465 3.1E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_24470 6c681f16da7a1321daac9d4b73512d0a 204 Pfam PF08044 Domain of unknown function (DUF1707) 17 69 2.9E-19 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_07110 782da038000d53ad73f095d6376eac8e 210 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 5 74 7.4E-20 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 TL08_07110 782da038000d53ad73f095d6376eac8e 210 Gene3D G3DSA:2.60.120.10 88 209 7.2E-8 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_07110 782da038000d53ad73f095d6376eac8e 210 SUPERFAMILY SSF51182 107 194 1.08E-10 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_26340 7bc6aecc88aed29d284a094520a17895 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 182 3.5E-4 T 12-10-2018 TL08_26340 7bc6aecc88aed29d284a094520a17895 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26340 7bc6aecc88aed29d284a094520a17895 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26340 7bc6aecc88aed29d284a094520a17895 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 6.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26340 7bc6aecc88aed29d284a094520a17895 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 9.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26340 7bc6aecc88aed29d284a094520a17895 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 9.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26340 7bc6aecc88aed29d284a094520a17895 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 9.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26340 7bc6aecc88aed29d284a094520a17895 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 9.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26340 7bc6aecc88aed29d284a094520a17895 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 9.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26340 7bc6aecc88aed29d284a094520a17895 257 PIRSF PIRSF000126 1 256 3.3E-67 T 12-10-2018 TL08_26340 7bc6aecc88aed29d284a094520a17895 257 Pfam PF00106 short chain dehydrogenase 3 189 5.8E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_26340 7bc6aecc88aed29d284a094520a17895 257 SUPERFAMILY SSF51735 3 250 1.77E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_26340 7bc6aecc88aed29d284a094520a17895 257 Gene3D G3DSA:3.40.50.720 1 255 2.6E-61 T 12-10-2018 TL08_23930 6714e68925aa8f03afdf43a5b54b0805 411 SUPERFAMILY SSF47413 5 72 5.93E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_23930 6714e68925aa8f03afdf43a5b54b0805 411 Pfam PF13560 Helix-turn-helix domain 10 64 8.2E-8 T 12-10-2018 TL08_23930 6714e68925aa8f03afdf43a5b54b0805 411 SUPERFAMILY SSF48452 163 375 7.59E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_23930 6714e68925aa8f03afdf43a5b54b0805 411 Gene3D G3DSA:1.10.260.40 8 73 2.7E-8 T 12-10-2018 TL08_08520 b6adc067a260adf0e90edfba4f5bbb7a 222 SUPERFAMILY SSF161098 16 210 2.62E-35 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08520 b6adc067a260adf0e90edfba4f5bbb7a 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 218 1.8E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_08520 b6adc067a260adf0e90edfba4f5bbb7a 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 113 1.6E-19 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TL08_08520 b6adc067a260adf0e90edfba4f5bbb7a 222 Gene3D G3DSA:1.10.3720.10 6 220 2.4E-42 T 12-10-2018 IPR035906 MetI-like superfamily TL08_17770 efaec0aed9e5f195d149f5a3d0b4ea20 113 Pfam PF12823 Domain of unknown function (DUF3817) 18 105 5.3E-26 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane TL08_17770 efaec0aed9e5f195d149f5a3d0b4ea20 113 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 20 103 1.5E-28 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane TL08_07540 21c34ab824828592e948caf7b45320ab 450 Pfam PF01757 Acyltransferase family 29 348 3.7E-18 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_09315 f6866ccd4d46f8def840817cfe823b66 186 SUPERFAMILY SSF55729 5 164 7.75E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_09315 f6866ccd4d46f8def840817cfe823b66 186 Gene3D G3DSA:3.40.630.30 5 179 3.2E-28 T 12-10-2018 TL08_09315 f6866ccd4d46f8def840817cfe823b66 186 Pfam PF00583 Acetyltransferase (GNAT) family 54 154 2.2E-4 T 12-10-2018 IPR000182 GNAT domain TL08_19920 72dac62a7b0e69046b10fa650c0da3b2 461 Gene3D G3DSA:3.40.190.10 65 420 6.3E-137 T 12-10-2018 TL08_19920 72dac62a7b0e69046b10fa650c0da3b2 461 SUPERFAMILY SSF53850 32 456 1.04E-78 T 12-10-2018 TL08_19920 72dac62a7b0e69046b10fa650c0da3b2 461 Pfam PF01547 Bacterial extracellular solute-binding protein 67 353 3.2E-50 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_19920 72dac62a7b0e69046b10fa650c0da3b2 461 Gene3D G3DSA:3.40.190.10 164 449 6.3E-137 T 12-10-2018 TL08_10685 e739b3cda4fb34f09aaa3faec8ccefc4 183 Pfam PF03061 Thioesterase superfamily 31 102 1.6E-17 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TL08_10685 e739b3cda4fb34f09aaa3faec8ccefc4 183 SUPERFAMILY SSF54637 16 163 1.87E-41 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_10685 e739b3cda4fb34f09aaa3faec8ccefc4 183 Gene3D G3DSA:3.10.129.10 4 169 9.9E-51 T 12-10-2018 TL08_19420 c947d9c0bcaa6d8e5840aef812aaf2b9 371 SUPERFAMILY SSF46689 6 74 3.54E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_19420 c947d9c0bcaa6d8e5840aef812aaf2b9 371 Gene3D G3DSA:1.10.357.10 3 192 1.5E-21 T 12-10-2018 TL08_19420 c947d9c0bcaa6d8e5840aef812aaf2b9 371 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 7.8E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19420 c947d9c0bcaa6d8e5840aef812aaf2b9 371 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 7.8E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19420 c947d9c0bcaa6d8e5840aef812aaf2b9 371 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 5.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_06755 1f92808138b4fa1e850c2b80a91c5666 349 Gene3D G3DSA:3.50.50.60 1 347 4.7E-104 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06755 1f92808138b4fa1e850c2b80a91c5666 349 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 1 199 1.0E-19 T 12-10-2018 TL08_06755 1f92808138b4fa1e850c2b80a91c5666 349 SUPERFAMILY SSF51905 1 201 1.18E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_06755 1f92808138b4fa1e850c2b80a91c5666 349 SUPERFAMILY SSF51905 166 345 2.37E-9 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_17730 a867e72436deabf6b4b3a08eede90411 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.0E-24 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17730 a867e72436deabf6b4b3a08eede90411 101 SUPERFAMILY SSF57716 2 101 2.49E-34 T 12-10-2018 TL08_17730 a867e72436deabf6b4b3a08eede90411 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.526 T 12-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid TL08_17730 a867e72436deabf6b4b3a08eede90411 101 Gene3D G3DSA:4.10.830.10 38 101 3.9E-24 T 12-10-2018 TL08_22865 86ac238059f65444f8454938035bd709 347 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 12 336 3.4E-16 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TL08_22865 86ac238059f65444f8454938035bd709 347 SUPERFAMILY SSF51726 12 340 9.42E-28 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TL08_22865 86ac238059f65444f8454938035bd709 347 Gene3D G3DSA:3.20.20.210 7 340 2.0E-26 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TL08_24410 54978ba859a05c994f1b1d02786949dd 409 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 328 5.4E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_18410 4790438900ea3d7d00c3acbd92417074 178 Pfam PF05145 Transition state regulatory protein AbrB 18 175 2.3E-26 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 TL08_18410 4790438900ea3d7d00c3acbd92417074 178 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 22 174 6.6E-30 T 12-10-2018 IPR017516 AbrB duplication TL08_19885 8324148091e570998c45b8431263ad91 191 SUPERFAMILY SSF48498 78 186 7.19E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_19885 8324148091e570998c45b8431263ad91 191 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 81 178 5.4E-9 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal TL08_19885 8324148091e570998c45b8431263ad91 191 Gene3D G3DSA:1.10.357.10 2 188 8.5E-27 T 12-10-2018 TL08_19885 8324148091e570998c45b8431263ad91 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 1.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19885 8324148091e570998c45b8431263ad91 191 SUPERFAMILY SSF46689 4 75 4.31E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_13290 958f244d693587a85d55ad229b89aea2 425 Pfam PF07005 Putative sugar-binding N-terminal domain 4 231 5.1E-66 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain TL08_13290 958f244d693587a85d55ad229b89aea2 425 Gene3D G3DSA:3.40.50.10840 1 241 1.2E-83 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily TL08_13290 958f244d693587a85d55ad229b89aea2 425 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 256 417 2.1E-33 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain TL08_13290 958f244d693587a85d55ad229b89aea2 425 SUPERFAMILY SSF142764 4 424 4.45E-106 T 12-10-2018 TL08_13290 958f244d693587a85d55ad229b89aea2 425 Gene3D G3DSA:3.40.980.20 242 425 2.7E-43 T 12-10-2018 TL08_14560 a9b5c8d10bb352aa58dbdfccd53f639f 135 SMART SM00886 2 90 0.004 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel TL08_14560 a9b5c8d10bb352aa58dbdfccd53f639f 135 Pfam PF07876 Stress responsive A/B Barrel Domain 2 89 1.6E-6 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel TL08_14560 a9b5c8d10bb352aa58dbdfccd53f639f 135 SUPERFAMILY SSF54909 1 93 3.13E-11 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_14270 deedec3b56bed45b3f7edc5aaf9fdc0a 277 Pfam PF02673 Bacitracin resistance protein BacA 6 264 2.6E-83 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TL08_14270 deedec3b56bed45b3f7edc5aaf9fdc0a 277 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 262 1.2E-83 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TL08_14270 deedec3b56bed45b3f7edc5aaf9fdc0a 277 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 269 17.95 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TL08_25495 1abcd779ad3884f3a919f448188e8d58 446 Pfam PF04286 Protein of unknown function (DUF445) 82 444 6.4E-110 T 12-10-2018 IPR007383 Protein of unknown function DUF445 TL08_24005 ea516beb85d08dca3cf90646fd82ed45 144 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 109 1.3E-24 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TL08_01415 8ebee11f1b1f974fa6b376e36f6c447b 441 PRINTS PR01228 Eggshell protein signature 229 240 2.9E-8 T 12-10-2018 TL08_01415 8ebee11f1b1f974fa6b376e36f6c447b 441 PRINTS PR01228 Eggshell protein signature 315 330 2.9E-8 T 12-10-2018 TL08_01415 8ebee11f1b1f974fa6b376e36f6c447b 441 PRINTS PR01228 Eggshell protein signature 370 388 2.9E-8 T 12-10-2018 TL08_01415 8ebee11f1b1f974fa6b376e36f6c447b 441 PRINTS PR01228 Eggshell protein signature 344 354 2.9E-8 T 12-10-2018 TL08_01415 8ebee11f1b1f974fa6b376e36f6c447b 441 SUPERFAMILY SSF140459 22 175 6.28E-6 T 12-10-2018 TL08_25245 6de7bbbe174a374e959cec38d3b5da01 187 Gene3D G3DSA:1.10.357.10 1 164 3.2E-14 T 12-10-2018 TL08_25245 6de7bbbe174a374e959cec38d3b5da01 187 SUPERFAMILY SSF46689 1 52 2.05E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_25245 6de7bbbe174a374e959cec38d3b5da01 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 29 2.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_11445 a4ed2272d446d45a130d16d44cd5ee1a 529 SUPERFAMILY SSF75005 154 348 1.36E-17 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_11445 a4ed2272d446d45a130d16d44cd5ee1a 529 Gene3D G3DSA:2.115.10.20 72 176 2.0E-12 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_11445 a4ed2272d446d45a130d16d44cd5ee1a 529 Gene3D G3DSA:2.115.10.20 177 355 1.7E-7 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_07855 8d07f9f64117cf81f2c35191e6f3993f 531 Pfam PF11941 Domain of unknown function (DUF3459) 454 530 3.5E-7 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) TL08_07855 8d07f9f64117cf81f2c35191e6f3993f 531 Gene3D G3DSA:3.90.400.10 117 189 4.1E-157 T 12-10-2018 TL08_07855 8d07f9f64117cf81f2c35191e6f3993f 531 SUPERFAMILY SSF51445 16 468 4.16E-121 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_07855 8d07f9f64117cf81f2c35191e6f3993f 531 Pfam PF00128 Alpha amylase, catalytic domain 40 383 8.7E-79 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_07855 8d07f9f64117cf81f2c35191e6f3993f 531 SMART SM00642 25 408 4.6E-115 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_07855 8d07f9f64117cf81f2c35191e6f3993f 531 Gene3D G3DSA:3.20.20.80 17 463 4.1E-157 T 12-10-2018 TL08_15835 19e348c0f5fd64de82ac32ef074a8cec 266 SUPERFAMILY SSF103481 13 105 1.57E-7 T 12-10-2018 TL08_15835 19e348c0f5fd64de82ac32ef074a8cec 266 Pfam PF00892 EamA-like transporter family 1 104 2.3E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_15835 19e348c0f5fd64de82ac32ef074a8cec 266 Pfam PF00892 EamA-like transporter family 121 252 1.0E-15 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TL08_15835 19e348c0f5fd64de82ac32ef074a8cec 266 SUPERFAMILY SSF103481 155 258 3.27E-10 T 12-10-2018 TL08_20185 ec0bbb24305842a314c5aa8652eed489 323 Gene3D G3DSA:3.90.245.10 2 321 1.7E-91 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like TL08_20185 ec0bbb24305842a314c5aa8652eed489 323 SUPERFAMILY SSF53590 4 318 1.19E-83 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like TL08_20185 ec0bbb24305842a314c5aa8652eed489 323 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 5 308 6.3E-74 T 12-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain TL08_21320 38662085697913487cee801c45df534e 311 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_21320 38662085697913487cee801c45df534e 311 SUPERFAMILY SSF52540 3 227 1.51E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21320 38662085697913487cee801c45df534e 311 Pfam PF00005 ABC transporter 20 157 5.3E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_21320 38662085697913487cee801c45df534e 311 SMART SM00382 28 206 7.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_21320 38662085697913487cee801c45df534e 311 Gene3D G3DSA:3.40.50.300 1 230 4.0E-64 T 12-10-2018 TL08_24450 05a3df3d796443a4ef285d7a18dfa0db 398 Pfam PF03631 Virulence factor BrkB 86 341 1.4E-46 T 12-10-2018 IPR017039 Virulence factor BrkB TL08_24450 05a3df3d796443a4ef285d7a18dfa0db 398 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 75 341 9.7E-67 T 12-10-2018 IPR005274 Inner membrane protein YhjD TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 Gene3D G3DSA:3.40.50.720 4 248 1.1E-84 T 12-10-2018 TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 1.1E-66 T 12-10-2018 TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 SUPERFAMILY SSF51735 5 246 3.01E-83 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_05675 c34ef47690e9c3a89a633d031ac478a1 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 221 2.0E-7 T 12-10-2018 TL08_18030 8d4ab1cfb8dbfeba088ba6797445223a 394 SUPERFAMILY SSF63999 179 301 9.55E-12 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TL08_18030 8d4ab1cfb8dbfeba088ba6797445223a 394 Pfam PF12555 Thiamine pyrophosphokinase C terminal 336 385 2.7E-6 T 12-10-2018 IPR022215 Thiamine pyrophosphokinase C-terminal TL08_01160 dafce14ca81ee613285d3cc0e5e7a1f8 185 SUPERFAMILY SSF52218 4 177 7.38E-33 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_01160 dafce14ca81ee613285d3cc0e5e7a1f8 185 Pfam PF03358 NADPH-dependent FMN reductase 4 143 8.2E-24 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TL08_01160 dafce14ca81ee613285d3cc0e5e7a1f8 185 Gene3D G3DSA:3.40.50.360 1 185 2.7E-40 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_09830 3bf1e7f33e616e4482cd10afcf457a7d 536 Gene3D G3DSA:1.20.1250.20 15 229 2.3E-43 T 12-10-2018 TL08_09830 3bf1e7f33e616e4482cd10afcf457a7d 536 Gene3D G3DSA:1.20.1250.20 274 456 3.5E-20 T 12-10-2018 TL08_09830 3bf1e7f33e616e4482cd10afcf457a7d 536 Pfam PF07690 Major Facilitator Superfamily 26 257 1.1E-25 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_09830 3bf1e7f33e616e4482cd10afcf457a7d 536 SUPERFAMILY SSF103473 8 453 8.63E-66 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_15360 f844763613a99ad241eaac2622afba2c 311 Pfam PF02779 Transketolase, pyrimidine binding domain 20 172 2.2E-18 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_15360 f844763613a99ad241eaac2622afba2c 311 SUPERFAMILY SSF52518 11 174 1.61E-31 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_15360 f844763613a99ad241eaac2622afba2c 311 Gene3D G3DSA:3.40.50.920 186 309 2.6E-11 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_15360 f844763613a99ad241eaac2622afba2c 311 Gene3D G3DSA:3.40.50.970 14 183 2.3E-34 T 12-10-2018 TL08_15360 f844763613a99ad241eaac2622afba2c 311 SUPERFAMILY SSF52922 186 267 4.06E-10 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TL08_15360 f844763613a99ad241eaac2622afba2c 311 SMART SM00861 14 180 2.9E-17 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TL08_04915 db3d292e22f2ff0aa995af9652e4bc9f 176 Pfam PF01863 Protein of unknown function DUF45 56 145 5.9E-20 T 12-10-2018 IPR002725 Protein of unknown function DUF45 TL08_04915 db3d292e22f2ff0aa995af9652e4bc9f 176 Gene3D G3DSA:3.30.2010.10 68 154 3.6E-10 T 12-10-2018 TL08_12650 5d5298a48bd109f351fa42b095e2cf65 382 Pfam PF00296 Luciferase-like monooxygenase 5 336 7.5E-87 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_12650 5d5298a48bd109f351fa42b095e2cf65 382 Gene3D G3DSA:3.20.20.30 1 366 3.0E-133 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_12650 5d5298a48bd109f351fa42b095e2cf65 382 SUPERFAMILY SSF51679 6 367 4.71E-93 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_15725 a893234f93f8ac2ecd0f1025ab8d42b0 390 Pfam PF01757 Acyltransferase family 21 377 9.2E-29 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_08980 d0609ec5eb93dc08e7aab9dc55158d06 84 Gene3D G3DSA:3.40.1620.10 3 43 2.0E-11 T 12-10-2018 TL08_08980 d0609ec5eb93dc08e7aab9dc55158d06 84 SUPERFAMILY SSF143120 8 49 7.06E-10 T 12-10-2018 IPR036165 YefM-like superfamily TL08_08980 d0609ec5eb93dc08e7aab9dc55158d06 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 45 7.8E-10 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TL08_08980 d0609ec5eb93dc08e7aab9dc55158d06 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 10 45 1.4E-7 T 12-10-2018 TL08_14920 7f75e499e6d6a363fee03358cc70d602 137 SUPERFAMILY SSF54427 5 133 5.49E-30 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_14920 7f75e499e6d6a363fee03358cc70d602 137 Pfam PF12680 SnoaL-like domain 22 119 1.2E-11 T 12-10-2018 IPR037401 SnoaL-like domain TL08_14920 7f75e499e6d6a363fee03358cc70d602 137 Gene3D G3DSA:3.10.450.50 1 136 1.7E-36 T 12-10-2018 TL08_07080 853023f6d7f520345c165f9af74426aa 160 Gene3D G3DSA:3.40.50.2300 1 155 1.1E-21 T 12-10-2018 TL08_07080 853023f6d7f520345c165f9af74426aa 160 SMART SM00226 1 154 1.6E-4 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TL08_07080 853023f6d7f520345c165f9af74426aa 160 SUPERFAMILY SSF52788 1 155 9.81E-17 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TL08_07080 853023f6d7f520345c165f9af74426aa 160 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 1 142 4.1E-9 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 Gene3D G3DSA:2.120.10.30 596 722 1.1E-11 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 SUPERFAMILY SSF82171 221 698 1.45E-28 T 12-10-2018 TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 Pfam PF07676 WD40-like Beta Propeller Repeat 537 556 2.4E-4 T 12-10-2018 IPR011659 WD40-like Beta Propeller TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 Pfam PF07676 WD40-like Beta Propeller Repeat 599 617 0.22 T 12-10-2018 IPR011659 WD40-like Beta Propeller TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 Pfam PF07676 WD40-like Beta Propeller Repeat 658 679 5.3E-4 T 12-10-2018 IPR011659 WD40-like Beta Propeller TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 Pfam PF07676 WD40-like Beta Propeller Repeat 484 505 3.1E-4 T 12-10-2018 IPR011659 WD40-like Beta Propeller TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 Pfam PF07676 WD40-like Beta Propeller Repeat 164 201 3.7E-8 T 12-10-2018 IPR011659 WD40-like Beta Propeller TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 SUPERFAMILY SSF69304 81 295 1.11E-20 T 12-10-2018 TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 Gene3D G3DSA:2.120.10.30 397 526 6.4E-12 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_17570 c4e9ff32127f8c299e1eb21be732384c 1086 Gene3D G3DSA:2.120.10.30 61 298 1.0E-31 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_20885 d32c8087f9a0cd8d76509aaf59bb38c3 290 SUPERFAMILY SSF47413 15 73 7.24E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_20885 d32c8087f9a0cd8d76509aaf59bb38c3 290 Gene3D G3DSA:1.10.260.40 19 76 7.2E-10 T 12-10-2018 TL08_20885 d32c8087f9a0cd8d76509aaf59bb38c3 290 Pfam PF13560 Helix-turn-helix domain 15 76 9.4E-12 T 12-10-2018 TL08_20885 d32c8087f9a0cd8d76509aaf59bb38c3 290 SMART SM00530 19 74 7.2E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_09035 1a74309dc9628ecc4fe6b8cebf68a61e 421 SUPERFAMILY SSF55874 304 409 2.22E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_09035 1a74309dc9628ecc4fe6b8cebf68a61e 421 Gene3D G3DSA:3.30.565.10 292 416 3.2E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_09035 1a74309dc9628ecc4fe6b8cebf68a61e 421 Pfam PF07730 Histidine kinase 214 279 6.7E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.6E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.6E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.6E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 7.5E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 Gene3D G3DSA:1.10.10.10 1 88 3.5E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 SUPERFAMILY SSF53850 91 277 5.07E-12 T 12-10-2018 TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 SUPERFAMILY SSF46785 5 88 3.51E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 Gene3D G3DSA:3.40.190.10 166 258 2.9E-10 T 12-10-2018 TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 Pfam PF03466 LysR substrate binding domain 91 277 1.9E-8 T 12-10-2018 IPR005119 LysR, substrate-binding TL08_21610 28566e59b9104f31e6160631d7cb2b56 291 Gene3D G3DSA:3.40.190.10 103 276 2.9E-10 T 12-10-2018 TL08_04310 92187aa4db44b470153a5ac16c11ea0b 282 SUPERFAMILY SSF160424 151 277 1.16E-5 T 12-10-2018 IPR036170 Probable antitoxin YezG superfamily TL08_04515 9cfd52ff77fab357143af557a6409ab3 271 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 87 261 5.0E-43 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG TL08_04515 9cfd52ff77fab357143af557a6409ab3 271 SUPERFAMILY SSF102405 58 260 2.14E-62 T 12-10-2018 TL08_04515 9cfd52ff77fab357143af557a6409ab3 271 Gene3D G3DSA:3.40.50.450 59 271 1.8E-68 T 12-10-2018 TL08_04515 9cfd52ff77fab357143af557a6409ab3 271 Pfam PF03641 Possible lysine decarboxylase 130 258 2.5E-31 T 12-10-2018 IPR031100 LOG family TL08_04695 33250ac834743fd701da5e7806791780 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 274 3.2E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_04695 33250ac834743fd701da5e7806791780 281 SUPERFAMILY SSF161098 12 281 3.74E-74 T 12-10-2018 IPR035906 MetI-like superfamily TL08_04695 33250ac834743fd701da5e7806791780 281 Gene3D G3DSA:1.10.3720.10 9 272 6.3E-67 T 12-10-2018 IPR035906 MetI-like superfamily TL08_07560 df37c5decb3757ff598927a2437c7f30 92 Pfam PF00403 Heavy-metal-associated domain 29 89 4.7E-15 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TL08_07560 df37c5decb3757ff598927a2437c7f30 92 PRINTS PR00944 Copper ion binding protein signature 77 90 1.2E-7 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 TL08_07560 df37c5decb3757ff598927a2437c7f30 92 PRINTS PR00944 Copper ion binding protein signature 27 39 1.2E-7 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 TL08_07560 df37c5decb3757ff598927a2437c7f30 92 PRINTS PR00944 Copper ion binding protein signature 52 65 1.2E-7 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 TL08_07560 df37c5decb3757ff598927a2437c7f30 92 PRINTS PR00944 Copper ion binding protein signature 39 52 1.2E-7 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 TL08_07560 df37c5decb3757ff598927a2437c7f30 92 Gene3D G3DSA:3.30.70.100 27 90 1.8E-19 T 12-10-2018 TL08_07560 df37c5decb3757ff598927a2437c7f30 92 ProSitePatterns PS01047 Heavy-metal-associated domain. 32 61 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TL08_07560 df37c5decb3757ff598927a2437c7f30 92 SUPERFAMILY SSF55008 22 91 8.38E-20 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TL08_09840 733c257c3abcd1107c5ba456a34afd81 176 Pfam PF01252 Signal peptidase (SPase) II 38 169 6.7E-28 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09840 733c257c3abcd1107c5ba456a34afd81 176 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 150 166 3.4E-14 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09840 733c257c3abcd1107c5ba456a34afd81 176 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 72 80 3.4E-14 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09840 733c257c3abcd1107c5ba456a34afd81 176 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 118 133 3.4E-14 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09840 733c257c3abcd1107c5ba456a34afd81 176 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 29 175 12.888 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09840 733c257c3abcd1107c5ba456a34afd81 176 TIGRFAM TIGR00077 lspA: signal peptidase II 34 170 1.7E-23 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TL08_09735 5d7c4e5a535a200276fa1fac398b0871 220 PIRSF PIRSF026622 6 212 2.2E-24 T 12-10-2018 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type TL08_09735 5d7c4e5a535a200276fa1fac398b0871 220 Pfam PF02517 CAAX protease self-immunity 87 198 1.4E-14 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TL08_03750 9a91b16301fedd2482f1fe53accbcc7a 281 SUPERFAMILY SSF53955 66 270 3.52E-33 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TL08_03750 9a91b16301fedd2482f1fe53accbcc7a 281 Pfam PF13406 Transglycosylase SLT domain 193 237 1.1E-6 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 TL08_03750 9a91b16301fedd2482f1fe53accbcc7a 281 Gene3D G3DSA:1.10.530.10 117 277 6.1E-9 T 12-10-2018 TL08_12960 c87aa485f7403af54065c452229504f2 405 Gene3D G3DSA:1.10.260.40 9 85 4.6E-13 T 12-10-2018 TL08_12960 c87aa485f7403af54065c452229504f2 405 Pfam PF13560 Helix-turn-helix domain 11 68 2.3E-12 T 12-10-2018 TL08_12960 c87aa485f7403af54065c452229504f2 405 SMART SM00530 14 70 1.7E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_12960 c87aa485f7403af54065c452229504f2 405 SUPERFAMILY SSF47413 10 73 1.52E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_09090 9449390970ed91a5af498bc5727347c4 457 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 398 407 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 TL08_09090 9449390970ed91a5af498bc5727347c4 457 Gene3D G3DSA:1.10.630.10 15 456 5.8E-67 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_09090 9449390970ed91a5af498bc5727347c4 457 PRINTS PR00359 B-class P450 signature 144 160 6.8E-12 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09090 9449390970ed91a5af498bc5727347c4 457 PRINTS PR00359 B-class P450 signature 286 297 6.8E-12 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09090 9449390970ed91a5af498bc5727347c4 457 PRINTS PR00359 B-class P450 signature 161 176 6.8E-12 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09090 9449390970ed91a5af498bc5727347c4 457 PRINTS PR00359 B-class P450 signature 303 330 6.8E-12 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 TL08_09090 9449390970ed91a5af498bc5727347c4 457 SUPERFAMILY SSF48264 34 453 2.45E-52 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 TL08_21050 290239a60c4893048056ebc109b301f5 327 SMART SM00943 13 218 3.2E-32 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TL08_21050 290239a60c4893048056ebc109b301f5 327 SUPERFAMILY SSF56747 60 210 2.75E-19 T 12-10-2018 TL08_21050 290239a60c4893048056ebc109b301f5 327 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 15 217 2.6E-32 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TL08_20985 c54464e60d5ea9a07f1dd8790d87e901 213 SUPERFAMILY SSF46689 14 90 1.8E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_20985 c54464e60d5ea9a07f1dd8790d87e901 213 Gene3D G3DSA:1.10.357.10 24 211 6.4E-47 T 12-10-2018 TL08_07220 ed272148bf2de7aed34aa8b85d8f9d67 264 Gene3D G3DSA:1.20.1260.10 82 256 3.3E-59 T 12-10-2018 IPR012347 Ferritin-like TL08_07220 ed272148bf2de7aed34aa8b85d8f9d67 264 Pfam PF03713 Domain of unknown function (DUF305) 89 252 4.3E-45 T 12-10-2018 IPR005183 Domain of unknown function DUF305 TL08_05705 2d29cd8eb95f4d57920947af167f9633 413 SUPERFAMILY SSF51905 5 375 2.54E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05705 2d29cd8eb95f4d57920947af167f9633 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.6E-7 T 12-10-2018 TL08_05705 2d29cd8eb95f4d57920947af167f9633 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 1.6E-7 T 12-10-2018 TL08_05705 2d29cd8eb95f4d57920947af167f9633 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.6E-7 T 12-10-2018 TL08_05705 2d29cd8eb95f4d57920947af167f9633 413 Gene3D G3DSA:3.50.50.60 4 389 1.1E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05705 2d29cd8eb95f4d57920947af167f9633 413 Pfam PF01494 FAD binding domain 5 321 4.0E-20 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TL08_01830 ba7698e47858adf82b57d7cc7465aa53 97 Pfam PF04149 Domain of unknown function (DUF397) 41 92 1.2E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_17135 d3e2787353f47a96fd3c675498208a97 377 Gene3D G3DSA:1.10.3470.10 43 376 1.6E-84 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_17135 d3e2787353f47a96fd3c675498208a97 377 SUPERFAMILY SSF81345 40 370 8.11E-66 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_17135 d3e2787353f47a96fd3c675498208a97 377 Pfam PF01032 FecCD transport family 56 370 2.6E-76 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_04770 4241579e12d63a5d1d4ea5bd20fdd898 76 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 9.8E-31 T 12-10-2018 IPR021456 Protein of unknown function DUF3107 TL08_24000 caed02c8dcbb3362877f029f7c2aace1 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 1.5E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_24000 caed02c8dcbb3362877f029f7c2aace1 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 375 401 1.5E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_24000 caed02c8dcbb3362877f029f7c2aace1 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 166 190 1.5E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_24000 caed02c8dcbb3362877f029f7c2aace1 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 323 342 1.5E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_24000 caed02c8dcbb3362877f029f7c2aace1 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 1.5E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_24000 caed02c8dcbb3362877f029f7c2aace1 510 Pfam PF00361 Proton-conducting membrane transporter 131 418 6.9E-61 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_17375 a4fb9666fac0e7ef539b5933b4528614 414 Gene3D G3DSA:3.40.190.10 27 357 2.1E-116 T 12-10-2018 TL08_17375 a4fb9666fac0e7ef539b5933b4528614 414 SUPERFAMILY SSF53850 13 412 1.3E-60 T 12-10-2018 TL08_17375 a4fb9666fac0e7ef539b5933b4528614 414 Gene3D G3DSA:3.40.190.10 136 405 2.1E-116 T 12-10-2018 TL08_17375 a4fb9666fac0e7ef539b5933b4528614 414 Pfam PF01547 Bacterial extracellular solute-binding protein 36 321 7.8E-27 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_13375 9e0c613bcc7457f2bbe94877a72d726a 309 Pfam PF03547 Membrane transport protein 13 148 4.8E-8 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TL08_13375 9e0c613bcc7457f2bbe94877a72d726a 309 Pfam PF03547 Membrane transport protein 159 304 5.0E-12 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TL08_10245 ba1d3260c8e1e235bc35f7b3f8a9c44a 288 Gene3D G3DSA:3.40.50.150 78 284 2.6E-37 T 12-10-2018 TL08_10245 ba1d3260c8e1e235bc35f7b3f8a9c44a 288 Pfam PF08241 Methyltransferase domain 91 187 9.6E-20 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TL08_10245 ba1d3260c8e1e235bc35f7b3f8a9c44a 288 SUPERFAMILY SSF53335 41 270 1.23E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_26185 3472c8db582434b82b8646928f6faf32 202 SUPERFAMILY SSF55961 8 143 1.85E-15 T 12-10-2018 TL08_26185 3472c8db582434b82b8646928f6faf32 202 Gene3D G3DSA:3.30.530.20 9 155 1.9E-10 T 12-10-2018 IPR023393 START-like domain superfamily TL08_26185 3472c8db582434b82b8646928f6faf32 202 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 15 144 4.8E-6 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase TL08_22110 644ba235630a5a3675f44ec608bc5775 330 Pfam PF03186 CobD/Cbib protein 9 290 1.7E-89 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TL08_22110 644ba235630a5a3675f44ec608bc5775 330 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 312 92.94 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TL08_22110 644ba235630a5a3675f44ec608bc5775 330 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 9 267 1.6E-50 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TL08_13555 02d2901c48db3ead0e6e2092183e5715 352 SUPERFAMILY SSF51735 136 303 2.45E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_13555 02d2901c48db3ead0e6e2092183e5715 352 Pfam PF16884 N-terminal domain of oxidoreductase 5 102 1.3E-16 T 12-10-2018 TL08_13555 02d2901c48db3ead0e6e2092183e5715 352 SMART SM00829 14 349 1.8E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TL08_13555 02d2901c48db3ead0e6e2092183e5715 352 Gene3D G3DSA:3.40.50.720 138 318 6.6E-81 T 12-10-2018 TL08_13555 02d2901c48db3ead0e6e2092183e5715 352 SUPERFAMILY SSF50129 3 147 4.38E-21 T 12-10-2018 IPR011032 GroES-like superfamily TL08_13555 02d2901c48db3ead0e6e2092183e5715 352 Gene3D G3DSA:3.90.180.10 24 349 6.6E-81 T 12-10-2018 TL08_13555 02d2901c48db3ead0e6e2092183e5715 352 Pfam PF00107 Zinc-binding dehydrogenase 170 293 5.3E-18 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TL08_26800 25e8a8f1adf7392752453df98e5872fe 187 SUPERFAMILY SSF46785 2 173 1.69E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_26800 25e8a8f1adf7392752453df98e5872fe 187 Gene3D G3DSA:1.10.10.10 1 96 1.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_26800 25e8a8f1adf7392752453df98e5872fe 187 Pfam PF03551 Transcriptional regulator PadR-like family 6 85 4.2E-18 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal TL08_23430 57aa8436c00dd4c4e6007aa3a6117cfb 307 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 6 298 9.1E-84 T 12-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TL08_23430 57aa8436c00dd4c4e6007aa3a6117cfb 307 Gene3D G3DSA:3.90.25.10 173 293 2.8E-89 T 12-10-2018 TL08_23430 57aa8436c00dd4c4e6007aa3a6117cfb 307 Pfam PF04321 RmlD substrate binding domain 6 299 2.2E-100 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TL08_23430 57aa8436c00dd4c4e6007aa3a6117cfb 307 Gene3D G3DSA:3.40.50.720 7 287 2.8E-89 T 12-10-2018 TL08_23430 57aa8436c00dd4c4e6007aa3a6117cfb 307 SUPERFAMILY SSF51735 6 298 1.7E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_17930 cbb62c8078c5f1ffda7403b003014525 132 Pfam PF14279 HNH endonuclease 27 72 2.2E-10 T 12-10-2018 IPR029471 HNH endonuclease 5 TL08_17930 cbb62c8078c5f1ffda7403b003014525 132 SMART SM00507 14 68 5.8E-7 T 12-10-2018 IPR003615 HNH nuclease TL08_17930 cbb62c8078c5f1ffda7403b003014525 132 Gene3D G3DSA:3.30.40.60 1 131 3.6E-17 T 12-10-2018 TL08_08630 d6eb5f387d7c63016e67f22a7dc9985c 345 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 328 3.7E-91 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TL08_08630 d6eb5f387d7c63016e67f22a7dc9985c 345 SUPERFAMILY SSF53659 3 330 2.24E-92 T 12-10-2018 TL08_08630 d6eb5f387d7c63016e67f22a7dc9985c 345 Gene3D G3DSA:3.40.718.10 1 329 3.1E-110 T 12-10-2018 TL08_08630 d6eb5f387d7c63016e67f22a7dc9985c 345 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 33 323 6.1E-87 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 TL08_00420 2d55c8c3b192c185052448bd22e1f607 146 Pfam PF14534 Domain of unknown function (DUF4440) 25 136 6.6E-9 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 TL08_00420 2d55c8c3b192c185052448bd22e1f607 146 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 21 146 2.0E-18 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 TL08_00420 2d55c8c3b192c185052448bd22e1f607 146 SUPERFAMILY SSF54427 19 145 3.55E-30 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_00420 2d55c8c3b192c185052448bd22e1f607 146 Gene3D G3DSA:3.10.450.50 10 145 1.4E-33 T 12-10-2018 TL08_23665 f9b2e265b155aafbd440c8bf9deacbf2 63 Pfam PF04149 Domain of unknown function (DUF397) 7 58 2.0E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_04660 349ca736d432e41e341116caa3cfe456 131 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 122 14.971 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 TL08_04660 349ca736d432e41e341116caa3cfe456 131 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 5 82 2.4E-20 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 TL08_04660 349ca736d432e41e341116caa3cfe456 131 Pfam PF02416 mttA/Hcf106 family 5 41 1.2E-7 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TL08_04660 349ca736d432e41e341116caa3cfe456 131 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 6.4E-11 T 12-10-2018 TL08_04660 349ca736d432e41e341116caa3cfe456 131 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 6.4E-11 T 12-10-2018 TL08_04660 349ca736d432e41e341116caa3cfe456 131 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 6.4E-11 T 12-10-2018 TL08_02210 2acbea07c0938d3ff01b81ffe7c2d928 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 7.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_02210 2acbea07c0938d3ff01b81ffe7c2d928 207 SUPERFAMILY SSF48498 91 202 2.03E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_02210 2acbea07c0938d3ff01b81ffe7c2d928 207 SUPERFAMILY SSF46689 14 93 1.55E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_02210 2acbea07c0938d3ff01b81ffe7c2d928 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 3.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_02210 2acbea07c0938d3ff01b81ffe7c2d928 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 3.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_02210 2acbea07c0938d3ff01b81ffe7c2d928 207 Gene3D G3DSA:1.10.357.10 9 206 8.2E-53 T 12-10-2018 TL08_22800 20ea7e3371b5435cd6c55b86bb3e7f84 440 Gene3D G3DSA:2.120.10.30 107 431 6.1E-45 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TL08_22800 20ea7e3371b5435cd6c55b86bb3e7f84 440 Pfam PF07995 Glucose / Sorbosone dehydrogenase 140 337 2.0E-15 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TL08_22800 20ea7e3371b5435cd6c55b86bb3e7f84 440 SUPERFAMILY SSF50952 126 374 3.79E-13 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TL08_03185 3bbfa0955f376dc977b295d9a2169402 353 SUPERFAMILY SSF51735 7 348 5.04E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_03185 3bbfa0955f376dc977b295d9a2169402 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 107 2.9E-8 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TL08_03185 3bbfa0955f376dc977b295d9a2169402 353 Gene3D G3DSA:3.40.50.720 2 353 3.9E-109 T 12-10-2018 TL08_12015 1d39c349ed1adb8453bb035ae5b472ca 376 SUPERFAMILY SSF54631 262 373 1.52E-5 T 12-10-2018 TL08_12015 1d39c349ed1adb8453bb035ae5b472ca 376 PIRSF PIRSF006404 16 376 1.6E-59 T 12-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS TL08_12015 1d39c349ed1adb8453bb035ae5b472ca 376 Pfam PF02163 Peptidase family M50 151 206 1.1E-6 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TL08_11325 51080a12bac1a604867fdddca398f813 244 Pfam PF05988 Bacterial protein of unknown function (DUF899) 13 154 1.4E-18 T 12-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like TL08_12145 9bfdab911c07adc9c35adc3615336bf5 359 SUPERFAMILY SSF52266 44 328 3.83E-37 T 12-10-2018 TL08_12145 9bfdab911c07adc9c35adc3615336bf5 359 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 46 319 4.1E-16 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain TL08_12145 9bfdab911c07adc9c35adc3615336bf5 359 Gene3D G3DSA:3.40.50.1110 38 330 5.4E-52 T 12-10-2018 IPR036514 SGNH hydrolase superfamily TL08_02450 75fbf55a2fe3c48b0bf2dbfa6d2d18cb 283 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 87 262 1.5E-33 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 TL08_01095 4b414b08217bfa249e935b6284217f8e 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 310 3.5E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_01095 4b414b08217bfa249e935b6284217f8e 311 Gene3D G3DSA:1.10.3720.10 96 310 7.2E-23 T 12-10-2018 IPR035906 MetI-like superfamily TL08_01095 4b414b08217bfa249e935b6284217f8e 311 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 83 3.8E-13 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TL08_01095 4b414b08217bfa249e935b6284217f8e 311 SUPERFAMILY SSF161098 102 291 5.89E-27 T 12-10-2018 IPR035906 MetI-like superfamily TL08_20425 7679bca11b26b735966338d9f279c4b6 274 Gene3D G3DSA:3.20.20.150 2 272 5.4E-67 T 12-10-2018 TL08_20425 7679bca11b26b735966338d9f279c4b6 274 Pfam PF01261 Xylose isomerase-like TIM barrel 43 219 1.4E-31 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_20425 7679bca11b26b735966338d9f279c4b6 274 SUPERFAMILY SSF51658 7 263 9.82E-55 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_10810 b5cf47a934b0227480a02c35c0b0d211 264 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 255 1.3E-74 T 12-10-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 TL08_10810 b5cf47a934b0227480a02c35c0b0d211 264 Pfam PF13522 Glutamine amidotransferase domain 84 199 7.2E-15 T 12-10-2018 TL08_10810 b5cf47a934b0227480a02c35c0b0d211 264 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 255 37.088 T 12-10-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 TL08_10810 b5cf47a934b0227480a02c35c0b0d211 264 SUPERFAMILY SSF56235 42 254 4.63E-20 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_10810 b5cf47a934b0227480a02c35c0b0d211 264 Gene3D G3DSA:3.60.20.10 2 260 4.9E-75 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TL08_01690 042a6fb0f73702d542cdac20c6888478 155 Pfam PF11377 Protein of unknown function (DUF3180) 12 144 8.3E-37 T 12-10-2018 IPR021517 Protein of unknown function DUF3180 TL08_12785 dc899e96a82deaee91ad7153f3d90a23 548 Gene3D G3DSA:3.10.105.10 303 518 6.0E-48 T 12-10-2018 TL08_12785 dc899e96a82deaee91ad7153f3d90a23 548 PIRSF PIRSF002741 15 547 1.5E-69 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TL08_12785 dc899e96a82deaee91ad7153f3d90a23 548 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 456 2.0E-70 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TL08_12785 dc899e96a82deaee91ad7153f3d90a23 548 SUPERFAMILY SSF53850 47 545 1.3E-105 T 12-10-2018 TL08_12785 dc899e96a82deaee91ad7153f3d90a23 548 Gene3D G3DSA:3.40.190.10 32 296 1.2E-51 T 12-10-2018 TL08_13775 08067b5ab562504e932ae5b4cda23253 179 Gene3D G3DSA:3.40.50.850 9 179 1.3E-36 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TL08_13775 08067b5ab562504e932ae5b4cda23253 179 Pfam PF00857 Isochorismatase family 11 146 1.8E-28 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 TL08_13775 08067b5ab562504e932ae5b4cda23253 179 SUPERFAMILY SSF52499 10 172 2.35E-34 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TL08_16830 b3eef8e65c8daaa2ee35383e70cd4c82 427 Pfam PF01757 Acyltransferase family 79 402 1.1E-23 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_21900 154824fdc1859b9b147d1a00a53c3b95 242 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 27 227 3.0E-71 T 12-10-2018 TL08_21900 154824fdc1859b9b147d1a00a53c3b95 242 Pfam PF13829 Domain of unknown function (DUF4191) 19 234 5.5E-86 T 12-10-2018 IPR025445 Protein of unknown function DUF4191 TL08_07575 b155fac905d0f867e3cd80b3e16b3c72 317 Pfam PF14100 Methane oxygenase PmoA 27 309 2.0E-68 T 12-10-2018 IPR029475 Methane oxygenase PmoA TL08_20795 0c700a4f62f7c9d81a75e633dbc3fd96 273 SUPERFAMILY SSF51126 57 228 2.55E-50 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TL08_20795 0c700a4f62f7c9d81a75e633dbc3fd96 273 Pfam PF03211 Pectate lyase 55 247 2.3E-72 T 12-10-2018 IPR004898 Pectate lyase PlyH/PlyE-like GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 TL08_20795 0c700a4f62f7c9d81a75e633dbc3fd96 273 Gene3D G3DSA:2.160.20.10 57 273 1.7E-71 T 12-10-2018 IPR012334 Pectin lyase fold TL08_07025 af17c666606190302ad908537661afe6 494 SUPERFAMILY SSF75011 139 447 1.7E-9 T 12-10-2018 TL08_07025 af17c666606190302ad908537661afe6 494 Pfam PF08309 LVIVD repeat 167 191 0.66 T 12-10-2018 IPR013211 LVIVD TL08_07025 af17c666606190302ad908537661afe6 494 Pfam PF08309 LVIVD repeat 94 126 1.3E-4 T 12-10-2018 IPR013211 LVIVD TL08_18300 68a72e94bcb1988e526c3fe9143c5fb1 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 1.8E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_03395 cb0bb41715925aaeb3f684480146fe89 201 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 74 155 1.5E-11 T 12-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 TL08_03395 cb0bb41715925aaeb3f684480146fe89 201 SUPERFAMILY SSF55166 71 181 3.92E-21 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TL08_03395 cb0bb41715925aaeb3f684480146fe89 201 Gene3D G3DSA:3.30.1380.10 42 184 6.0E-15 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TL08_01755 7c1864c102d6e33cdbfd62b3c4512d90 287 Gene3D G3DSA:3.40.50.1220 15 256 2.3E-38 T 12-10-2018 TL08_01755 7c1864c102d6e33cdbfd62b3c4512d90 287 SUPERFAMILY SSF52467 5 277 3.46E-61 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TL08_01755 7c1864c102d6e33cdbfd62b3c4512d90 287 Gene3D G3DSA:3.30.1600.10 33 188 2.3E-38 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily TL08_01755 7c1864c102d6e33cdbfd62b3c4512d90 287 Pfam PF02146 Sir2 family 24 189 4.0E-18 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 TL08_04625 c986d1b8f82848524ccb5cf898bf69a0 394 Pfam PF07690 Major Facilitator Superfamily 2 218 3.8E-26 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_04625 c986d1b8f82848524ccb5cf898bf69a0 394 Pfam PF07690 Major Facilitator Superfamily 234 375 3.4E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_04625 c986d1b8f82848524ccb5cf898bf69a0 394 Gene3D G3DSA:1.20.1250.20 1 378 1.2E-45 T 12-10-2018 TL08_04625 c986d1b8f82848524ccb5cf898bf69a0 394 SUPERFAMILY SSF103473 2 374 3.66E-50 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_22540 13e257e3d5f1cc8c2aac8d783c9f4f44 243 Pfam PF10067 Predicted membrane protein (DUF2306) 58 208 8.1E-37 T 12-10-2018 IPR018750 Protein of unknown function DUF2306, membrane TL08_26935 119cec4776c9582d4b2bbed75d53eb19 398 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 229 397 2.3E-44 T 12-10-2018 IPR000160 GGDEF domain TL08_26935 119cec4776c9582d4b2bbed75d53eb19 398 SUPERFAMILY SSF55073 237 396 4.79E-41 T 12-10-2018 IPR029787 Nucleotide cyclase TL08_26935 119cec4776c9582d4b2bbed75d53eb19 398 Pfam PF00990 Diguanylate cyclase, GGDEF domain 231 393 1.7E-41 T 12-10-2018 IPR000160 GGDEF domain TL08_26935 119cec4776c9582d4b2bbed75d53eb19 398 Gene3D G3DSA:3.30.70.270 226 398 5.3E-49 T 12-10-2018 TL08_26935 119cec4776c9582d4b2bbed75d53eb19 398 SMART SM00267 220 398 5.2E-46 T 12-10-2018 IPR000160 GGDEF domain TL08_11855 078c251d18549a36122268867227f82c 424 Gene3D G3DSA:3.50.50.60 3 321 5.2E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_11855 078c251d18549a36122268867227f82c 424 SUPERFAMILY SSF51905 3 348 1.12E-18 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_11855 078c251d18549a36122268867227f82c 424 Gene3D G3DSA:3.30.9.50 37 269 5.2E-10 T 12-10-2018 TL08_11855 078c251d18549a36122268867227f82c 424 Pfam PF05834 Lycopene cyclase protein 3 380 8.7E-60 T 12-10-2018 TL08_13550 c072d5a044ddc93037076d2513f696f0 568 Gene3D G3DSA:3.50.50.60 178 310 5.6E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_13550 c072d5a044ddc93037076d2513f696f0 568 Gene3D G3DSA:3.50.50.60 1 90 2.0E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_13550 c072d5a044ddc93037076d2513f696f0 568 SUPERFAMILY SSF51905 2 518 1.55E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_13550 c072d5a044ddc93037076d2513f696f0 568 Pfam PF13450 NAD(P)-binding Rossmann-like domain 3 66 6.6E-12 T 12-10-2018 TL08_23575 f191c83871177f9d720d3740d2409659 864 Gene3D G3DSA:1.10.287.1060 22 113 7.6E-7 T 12-10-2018 TL08_23575 f191c83871177f9d720d3740d2409659 864 Pfam PF14021 Tuberculosis necrotizing toxin 757 840 7.6E-25 T 12-10-2018 IPR025331 Tuberculosis necrotizing toxin KEGG: 00760+3.2.2.5 TL08_15165 5e4135614925dfc2f2b0fa8f256a08c3 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 326 4.0E-45 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_11945 3ea961c609eb607a01ac489beccc1820 405 Gene3D G3DSA:2.120.10.10 42 403 3.7E-104 T 12-10-2018 TL08_11945 3ea961c609eb607a01ac489beccc1820 405 SUPERFAMILY SSF50939 46 404 5.05E-92 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TL08_11945 3ea961c609eb607a01ac489beccc1820 405 Pfam PF13088 BNR repeat-like domain 70 377 8.5E-41 T 12-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TL08_00180 ccd8030ba442255db12116cd45508b2e 220 SUPERFAMILY SSF51735 6 211 2.22E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_00180 ccd8030ba442255db12116cd45508b2e 220 Gene3D G3DSA:3.40.50.720 6 220 7.9E-45 T 12-10-2018 TL08_00180 ccd8030ba442255db12116cd45508b2e 220 Pfam PF13460 NAD(P)H-binding 11 197 1.5E-40 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_02765 57abb3dff3749f4ff7d1639c7b463119 76 SUPERFAMILY SSF55298 1 75 7.54E-17 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_02765 57abb3dff3749f4ff7d1639c7b463119 76 Gene3D G3DSA:3.30.1330.40 1 76 5.3E-19 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_02765 57abb3dff3749f4ff7d1639c7b463119 76 Pfam PF01042 Endoribonuclease L-PSP 1 75 5.7E-11 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TL08_20210 dcf7367a2dc1d14a66c61efca223c756 258 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 1 202 4.7E-38 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TL08_06860 a1f4675f1acb5dcc9873f6fe4ff8ca27 216 SUPERFAMILY SSF46689 8 81 1.47E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_06860 a1f4675f1acb5dcc9873f6fe4ff8ca27 216 SUPERFAMILY SSF48498 92 213 6.67E-28 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_06860 a1f4675f1acb5dcc9873f6fe4ff8ca27 216 Gene3D G3DSA:1.10.357.10 3 215 6.6E-76 T 12-10-2018 TL08_06860 a1f4675f1acb5dcc9873f6fe4ff8ca27 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 5.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_01805 d771243ff2db00b99f85f25791c6eede 172 ProSitePatterns PS00893 Nudix box signature. 58 79 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_01805 d771243ff2db00b99f85f25791c6eede 172 Gene3D G3DSA:3.90.79.10 23 167 5.5E-21 T 12-10-2018 TL08_01805 d771243ff2db00b99f85f25791c6eede 172 Pfam PF00293 NUDIX domain 27 139 1.3E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_01805 d771243ff2db00b99f85f25791c6eede 172 SUPERFAMILY SSF55811 26 144 1.62E-21 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_09965 8a79735baf9230de66df898e451122a9 887 SUPERFAMILY SSF53822 591 875 2.65E-7 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_09965 8a79735baf9230de66df898e451122a9 887 Gene3D G3DSA:3.40.50.2300 622 768 1.2E-6 T 12-10-2018 TL08_09965 8a79735baf9230de66df898e451122a9 887 Gene3D G3DSA:3.40.50.2300 562 860 1.2E-6 T 12-10-2018 TL08_10355 a3a3b9b473a8de0ee3067462daba0c67 394 Pfam PF13439 Glycosyltransferase Family 4 14 173 9.7E-25 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_10355 a3a3b9b473a8de0ee3067462daba0c67 394 Gene3D G3DSA:3.40.50.2000 171 348 7.7E-116 T 12-10-2018 TL08_10355 a3a3b9b473a8de0ee3067462daba0c67 394 Pfam PF13692 Glycosyl transferases group 1 190 330 5.4E-29 T 12-10-2018 TL08_10355 a3a3b9b473a8de0ee3067462daba0c67 394 SUPERFAMILY SSF53756 6 365 2.83E-72 T 12-10-2018 TL08_10355 a3a3b9b473a8de0ee3067462daba0c67 394 Gene3D G3DSA:3.40.50.2000 12 361 7.7E-116 T 12-10-2018 TL08_19225 7e1b4b4e36bb75129c2c72a17e0f2e88 169 Pfam PF11706 CGNR zinc finger 119 161 3.5E-17 T 12-10-2018 IPR021005 Zinc finger, CGNR TL08_19225 7e1b4b4e36bb75129c2c72a17e0f2e88 169 SUPERFAMILY SSF160904 5 161 9.29E-33 T 12-10-2018 TL08_19225 7e1b4b4e36bb75129c2c72a17e0f2e88 169 Gene3D G3DSA:1.10.3300.10 3 163 1.2E-21 T 12-10-2018 IPR023286 ABATE domain superfamily TL08_17405 56258c840145ced902e0a9b023f78985 212 Gene3D G3DSA:3.40.50.10420 39 212 2.6E-57 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TL08_17405 56258c840145ced902e0a9b023f78985 212 Pfam PF02589 LUD domain 109 211 3.1E-21 T 12-10-2018 IPR003741 LUD domain TL08_17405 56258c840145ced902e0a9b023f78985 212 SUPERFAMILY SSF100950 41 211 7.11E-40 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TL08_07740 ddcaeb23d3931e3918ed9c26484cf0de 120 Pfam PF13788 Domain of unknown function (DUF4180) 8 116 9.9E-35 T 12-10-2018 IPR025438 Domain of unknown function DUF4180 TL08_21300 3545b608c7d4a7cebe87a5468f8360ad 378 Pfam PF03773 Predicted permease 95 372 3.1E-49 T 12-10-2018 IPR005524 Predicted permease DUF318 TL08_20265 47100d0d862c5110f67cc2cf3f039ba3 345 SUPERFAMILY SSF53807 40 336 8.24E-31 T 12-10-2018 TL08_20265 47100d0d862c5110f67cc2cf3f039ba3 345 Gene3D G3DSA:3.40.50.1980 27 168 1.4E-34 T 12-10-2018 TL08_20265 47100d0d862c5110f67cc2cf3f039ba3 345 Gene3D G3DSA:3.40.50.1980 172 343 1.5E-27 T 12-10-2018 TL08_20265 47100d0d862c5110f67cc2cf3f039ba3 345 Pfam PF01497 Periplasmic binding protein 73 294 5.7E-18 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TL08_10235 8ccbd928bba4dbf9902792eff68a95d8 237 SUPERFAMILY SSF52540 3 162 4.13E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10235 8ccbd928bba4dbf9902792eff68a95d8 237 Gene3D G3DSA:3.40.50.300 3 162 5.8E-14 T 12-10-2018 TL08_10235 8ccbd928bba4dbf9902792eff68a95d8 237 Pfam PF00005 ABC transporter 19 64 1.1E-5 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_23695 9242134b2d1670510202cf7fcd858e22 244 Pfam PF01738 Dienelactone hydrolase family 16 239 8.7E-40 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TL08_23695 9242134b2d1670510202cf7fcd858e22 244 SUPERFAMILY SSF53474 1 241 5.03E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_23695 9242134b2d1670510202cf7fcd858e22 244 Gene3D G3DSA:3.40.50.1820 1 241 3.6E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_10230 511705bbe678a757ba6a57b5968ff8da 711 Pfam PF12051 Protein of unknown function (DUF3533) 31 187 1.6E-6 T 12-10-2018 IPR022703 Domain of unknown function DUF3533 TL08_10230 511705bbe678a757ba6a57b5968ff8da 711 Pfam PF01061 ABC-2 type transporter 519 665 1.8E-10 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_10230 511705bbe678a757ba6a57b5968ff8da 711 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 9.1E-41 T 12-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal TL08_10230 511705bbe678a757ba6a57b5968ff8da 711 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 493 697 2.1E-50 T 12-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal TL08_11245 83557cef0e6614e98164c9b9a1504412 393 Pfam PF13556 PucR C-terminal helix-turn-helix domain 327 384 3.9E-16 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain TL08_11245 83557cef0e6614e98164c9b9a1504412 393 Gene3D G3DSA:1.10.10.2840 261 389 4.2E-21 T 12-10-2018 TL08_17695 ec85b13e584e040be966abd589fc901c 279 SUPERFAMILY SSF55781 95 275 2.55E-47 T 12-10-2018 TL08_17695 ec85b13e584e040be966abd589fc901c 279 Gene3D G3DSA:1.10.10.10 19 97 5.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_17695 ec85b13e584e040be966abd589fc901c 279 SUPERFAMILY SSF46785 32 102 9.97E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_17695 ec85b13e584e040be966abd589fc901c 279 Pfam PF09339 IclR helix-turn-helix domain 32 81 4.5E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_17695 ec85b13e584e040be966abd589fc901c 279 SMART SM00346 30 119 2.6E-19 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TL08_17695 ec85b13e584e040be966abd589fc901c 279 Gene3D G3DSA:3.30.450.40 103 277 2.3E-53 T 12-10-2018 IPR029016 GAF-like domain superfamily TL08_17695 ec85b13e584e040be966abd589fc901c 279 Pfam PF01614 Bacterial transcriptional regulator 147 269 5.7E-28 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TL08_15665 3e2ac07ebeff9cc713902a030069cf60 198 SUPERFAMILY SSF48498 85 195 1.7E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_15665 3e2ac07ebeff9cc713902a030069cf60 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15665 3e2ac07ebeff9cc713902a030069cf60 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 4.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15665 3e2ac07ebeff9cc713902a030069cf60 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 1.3E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_15665 3e2ac07ebeff9cc713902a030069cf60 198 SUPERFAMILY SSF46689 8 86 3.3E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_15665 3e2ac07ebeff9cc713902a030069cf60 198 Gene3D G3DSA:1.10.357.10 3 198 7.3E-55 T 12-10-2018 TL08_07835 b5283f2e1af9d1fb12d84b0b36d31403 1544 Gene3D G3DSA:1.25.40.10 146 376 4.3E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_00185 e9130590875486d10a42ffc732c18504 1114 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 766 920 5.7E-18 T 12-10-2018 IPR007817 Pyoverdine biosynthesis TL08_10190 d7d180e50ed3d3ada3c493363394b89f 403 Pfam PF13458 Periplasmic binding protein 65 394 2.1E-43 T 12-10-2018 IPR028081 Leucine-binding protein domain TL08_10190 d7d180e50ed3d3ada3c493363394b89f 403 Gene3D G3DSA:3.40.50.2300 67 377 3.6E-73 T 12-10-2018 TL08_10190 d7d180e50ed3d3ada3c493363394b89f 403 Gene3D G3DSA:3.40.50.2300 182 307 3.6E-73 T 12-10-2018 TL08_10190 d7d180e50ed3d3ada3c493363394b89f 403 SUPERFAMILY SSF53822 63 397 3.36E-67 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TL08_22125 e23ee8a1fe85d364d162e9ad5c1559d6 1388 TIGRFAM TIGR02680 TIGR02680: TIGR02680 family protein 6 1382 8.4E-205 T 12-10-2018 IPR013496 Conserved hypothetical protein CHP02680 TL08_22125 e23ee8a1fe85d364d162e9ad5c1559d6 1388 Gene3D G3DSA:3.40.50.300 1132 1341 2.5E-5 T 12-10-2018 TL08_22125 e23ee8a1fe85d364d162e9ad5c1559d6 1388 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1241 1334 3.9E-19 T 12-10-2018 TL08_22125 e23ee8a1fe85d364d162e9ad5c1559d6 1388 SUPERFAMILY SSF52540 19 1336 1.44E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_05310 2c29d4638bd139afdfd6b5109f65d9db 155 Gene3D G3DSA:1.10.10.10 2 84 3.4E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_05310 2c29d4638bd139afdfd6b5109f65d9db 155 Pfam PF12802 MarR family 19 78 1.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_05310 2c29d4638bd139afdfd6b5109f65d9db 155 SUPERFAMILY SSF46785 11 109 2.06E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_14055 c942ef9b6bc6b80f3260286f79849b7b 140 Gene3D G3DSA:1.10.10.10 2 139 9.2E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_14055 c942ef9b6bc6b80f3260286f79849b7b 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 2.3E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_14055 c942ef9b6bc6b80f3260286f79849b7b 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 2.3E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_14055 c942ef9b6bc6b80f3260286f79849b7b 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 2.3E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_14055 c942ef9b6bc6b80f3260286f79849b7b 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 2.3E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_14055 c942ef9b6bc6b80f3260286f79849b7b 140 SUPERFAMILY SSF46785 9 137 4.97E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_14055 c942ef9b6bc6b80f3260286f79849b7b 140 Pfam PF01047 MarR family 34 90 3.3E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_14055 c942ef9b6bc6b80f3260286f79849b7b 140 SMART SM00347 27 126 1.3E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_06190 ba830e3757d796178ee970effd8d50d8 287 Pfam PF02517 CAAX protease self-immunity 129 234 5.0E-11 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TL08_14955 38addc2ef6400760e2d6080908079239 261 Pfam PF03737 Aldolase/RraA 50 216 2.1E-30 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TL08_14955 38addc2ef6400760e2d6080908079239 261 SUPERFAMILY SSF89562 50 227 5.49E-37 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TL08_14955 38addc2ef6400760e2d6080908079239 261 Gene3D G3DSA:3.50.30.100 17 239 2.2E-54 T 12-10-2018 TL08_17720 f9add226054df010a79ab0f80b2721c5 78 Gene3D G3DSA:2.30.170.40 2 78 1.1E-26 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17720 f9add226054df010a79ab0f80b2721c5 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.2E-25 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17720 f9add226054df010a79ab0f80b2721c5 78 Pfam PF00830 Ribosomal L28 family 4 61 3.8E-23 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_17720 f9add226054df010a79ab0f80b2721c5 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 19.486 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TL08_17720 f9add226054df010a79ab0f80b2721c5 78 SUPERFAMILY SSF143800 2 75 2.94E-26 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TL08_13260 3aaa0e9604f04bcf85c7dfe729bbf957 202 SUPERFAMILY SSF52540 17 189 7.75E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13260 3aaa0e9604f04bcf85c7dfe729bbf957 202 Gene3D G3DSA:3.40.50.300 15 199 1.6E-39 T 12-10-2018 TL08_13260 3aaa0e9604f04bcf85c7dfe729bbf957 202 Pfam PF06414 Zeta toxin 11 102 1.5E-8 T 12-10-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 TL08_20995 3c3aface2199709c15f1440310344cfd 131 Gene3D G3DSA:3.10.180.10 1 131 1.2E-53 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_20995 3c3aface2199709c15f1440310344cfd 131 SUPERFAMILY SSF54593 5 128 2.55E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_26365 a4f82fd675936d32251b493e03d8523d 228 Gene3D G3DSA:1.10.3630.10 1 217 1.8E-20 T 12-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily TL08_26365 a4f82fd675936d32251b493e03d8523d 228 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 8 206 8.6E-40 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 TL08_00935 2327b8d8e0650a9e5761e4c7aadc676c 389 SUPERFAMILY SSF50939 20 383 1.99E-49 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TL08_00935 2327b8d8e0650a9e5761e4c7aadc676c 389 Gene3D G3DSA:2.120.10.10 17 302 1.7E-36 T 12-10-2018 TL08_00935 2327b8d8e0650a9e5761e4c7aadc676c 389 Pfam PF13088 BNR repeat-like domain 34 364 6.6E-63 T 12-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 TL08_01815 a8390506311c21c4c8053c07e56e7d79 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 114 146 2.2E-5 T 12-10-2018 IPR001451 Hexapeptide repeat TL08_01815 a8390506311c21c4c8053c07e56e7d79 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 62 95 8.6E-6 T 12-10-2018 IPR001451 Hexapeptide repeat TL08_01815 a8390506311c21c4c8053c07e56e7d79 273 SUPERFAMILY SSF51161 60 272 4.72E-32 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TL08_01815 a8390506311c21c4c8053c07e56e7d79 273 Gene3D G3DSA:2.160.10.10 44 269 6.7E-39 T 12-10-2018 TL08_01815 a8390506311c21c4c8053c07e56e7d79 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 228 256 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TL08_19685 1b04dc8dbd7603bd96f2d063079cadaf 338 Gene3D G3DSA:3.40.50.300 15 337 1.3E-96 T 12-10-2018 TL08_19685 1b04dc8dbd7603bd96f2d063079cadaf 338 SMART SM00382 46 245 8.2E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_19685 1b04dc8dbd7603bd96f2d063079cadaf 338 Pfam PF00005 ABC transporter 38 195 3.7E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_19685 1b04dc8dbd7603bd96f2d063079cadaf 338 SUPERFAMILY SSF52540 18 266 1.44E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19685 1b04dc8dbd7603bd96f2d063079cadaf 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 246 331 9.2E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_19685 1b04dc8dbd7603bd96f2d063079cadaf 338 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_19685 1b04dc8dbd7603bd96f2d063079cadaf 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 311 7.5E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TL08_00780 e85c0dfc1e5d9f714424509e3009cd53 234 SUPERFAMILY SSF53474 4 233 4.55E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_00780 e85c0dfc1e5d9f714424509e3009cd53 234 Gene3D G3DSA:3.40.50.1820 4 231 1.7E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_00780 e85c0dfc1e5d9f714424509e3009cd53 234 Pfam PF01738 Dienelactone hydrolase family 17 232 1.3E-24 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 TL08_01305 b6783499590f87997e71cc8d0f088291 249 Gene3D G3DSA:3.90.79.10 41 216 1.9E-34 T 12-10-2018 TL08_01305 b6783499590f87997e71cc8d0f088291 249 SUPERFAMILY SSF55811 54 209 2.44E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_01305 b6783499590f87997e71cc8d0f088291 249 Pfam PF00293 NUDIX domain 54 174 7.3E-12 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_19230 879a92433a022f83cfe7f786616ee03d 65 Pfam PF04149 Domain of unknown function (DUF397) 9 60 4.9E-12 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_15015 c858eb53cf56f81d61d3bb312abe4f78 370 Pfam PF12102 Domain of unknown function (DUF3578) 13 191 6.1E-36 T 12-10-2018 IPR021961 Protein of unknown function DUF3578 TL08_15015 c858eb53cf56f81d61d3bb312abe4f78 370 Pfam PF13020 Domain of unknown function (DUF3883) 246 323 1.8E-6 T 12-10-2018 IPR024975 Domain of unknown function DUF3883 TL08_07085 0845727390c39646931c376d3b31c6a1 405 Pfam PF07730 Histidine kinase 150 255 6.2E-6 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_07085 0845727390c39646931c376d3b31c6a1 405 Gene3D G3DSA:3.30.565.10 269 395 1.5E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_07085 0845727390c39646931c376d3b31c6a1 405 SUPERFAMILY SSF55874 277 393 5.59E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_26500 62a13864c260c4fed7fff294aec5a8fe 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 5.3E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_01825 541490dd61b72216a1bd7f25b65af3b3 63 Pfam PF04149 Domain of unknown function (DUF397) 7 58 2.7E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_26465 8f8a08ef0a166ad976850a8facb43664 170 SUPERFAMILY SSF88697 18 136 4.67E-7 T 12-10-2018 IPR015947 PUA-like superfamily TL08_08945 5e311388a7180b663316742178e7fd42 415 Pfam PF02163 Peptidase family M50 24 365 1.2E-48 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TL08_08945 5e311388a7180b663316742178e7fd42 415 Gene3D G3DSA:2.30.42.10 170 255 1.5E-10 T 12-10-2018 TL08_08945 5e311388a7180b663316742178e7fd42 415 SUPERFAMILY SSF50156 118 226 1.21E-9 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TL08_09970 d84fc038f784607b7b900a1def2d419e 183 Gene3D G3DSA:1.10.10.10 13 61 7.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_09970 d84fc038f784607b7b900a1def2d419e 183 SMART SM00344 14 121 2.2E-23 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TL08_09970 d84fc038f784607b7b900a1def2d419e 183 SUPERFAMILY SSF46785 14 70 3.67E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_09970 d84fc038f784607b7b900a1def2d419e 183 Gene3D G3DSA:3.30.70.920 62 154 2.8E-15 T 12-10-2018 TL08_09970 d84fc038f784607b7b900a1def2d419e 183 Pfam PF01037 Lrp/AsnC ligand binding domain 81 150 1.5E-13 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TL08_09970 d84fc038f784607b7b900a1def2d419e 183 Pfam PF13404 AsnC-type helix-turn-helix domain 14 54 5.6E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_09970 d84fc038f784607b7b900a1def2d419e 183 SUPERFAMILY SSF54909 76 151 3.22E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_09970 d84fc038f784607b7b900a1def2d419e 183 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 14 30 3.5E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_09970 d84fc038f784607b7b900a1def2d419e 183 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 41 60 3.5E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_09970 d84fc038f784607b7b900a1def2d419e 183 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 41 3.5E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TL08_06450 9b17eb5d873a5ec20f9b9c7e32ecb3a0 191 Gene3D G3DSA:3.40.50.850 2 185 1.8E-58 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TL08_06450 9b17eb5d873a5ec20f9b9c7e32ecb3a0 191 Pfam PF00857 Isochorismatase family 4 182 3.0E-29 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 TL08_06450 9b17eb5d873a5ec20f9b9c7e32ecb3a0 191 SUPERFAMILY SSF52499 3 182 2.62E-44 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TL08_24800 d31b9681eff58d8d8d25c9df7e9691f0 100 Pfam PF02467 Transcription factor WhiB 17 85 2.2E-24 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TL08_24800 d31b9681eff58d8d8d25c9df7e9691f0 100 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 18.752 T 12-10-2018 IPR003482 Transcription factor WhiB TL08_03555 fe5e6e50c1a1cc7f11f5611e4f07f44b 137 Pfam PF04075 F420H(2)-dependent quinone reductase 23 101 2.8E-9 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 TL08_03555 fe5e6e50c1a1cc7f11f5611e4f07f44b 137 Gene3D G3DSA:2.30.110.10 11 113 2.9E-13 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TL08_02655 50040cfb66967f8d166dc430948beb9c 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 1.0E-23 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TL08_02655 50040cfb66967f8d166dc430948beb9c 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 20.101 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 TL08_09305 d39eb6ba280c9015b0b563f9f8bc7a5e 140 SUPERFAMILY SSF48452 93 138 1.14E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_09305 d39eb6ba280c9015b0b563f9f8bc7a5e 140 Gene3D G3DSA:1.25.40.10 81 140 1.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TL08_07320 42a09f7a07d22e01a15df2df47eb3612 275 Hamap MF_01416 ATP synthase subunit delta [atpD]. 47 275 14.002 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07320 42a09f7a07d22e01a15df2df47eb3612 275 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 110 273 1.6E-19 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07320 42a09f7a07d22e01a15df2df47eb3612 275 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 235 254 - T 12-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_07320 42a09f7a07d22e01a15df2df47eb3612 275 Pfam PF00213 ATP synthase delta (OSCP) subunit 110 273 3.5E-30 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 TL08_06740 839bd48e454c78418f12f0872357942f 256 SUPERFAMILY SSF53474 10 247 1.51E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06740 839bd48e454c78418f12f0872357942f 256 Gene3D G3DSA:3.40.50.1820 7 250 3.4E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06740 839bd48e454c78418f12f0872357942f 256 SMART SM00824 Thioesterase 27 247 0.0038 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 TL08_06740 839bd48e454c78418f12f0872357942f 256 Pfam PF00975 Thioesterase domain 25 244 1.5E-44 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 TL08_21185 22e6f50d3915cb6fb2a4c592a0a62dae 246 PIRSF PIRSF006648 2 245 4.3E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_21185 22e6f50d3915cb6fb2a4c592a0a62dae 246 Pfam PF01061 ABC-2 type transporter 6 212 1.8E-23 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_17525 12faa18f56f22406c97561d5372e159b 432 Pfam PF02687 FtsX-like permease family 335 424 5.2E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TL08_04755 05eac18768e37f60a9240e07d6242cf9 402 Gene3D G3DSA:2.130.10.10 22 216 1.0E-5 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TL08_04755 05eac18768e37f60a9240e07d6242cf9 402 SUPERFAMILY SSF50998 58 377 1.32E-6 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TL08_14715 def424a7f4148383458bd8d279e05c23 345 Gene3D G3DSA:2.115.10.20 167 344 3.2E-7 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_14715 def424a7f4148383458bd8d279e05c23 345 Gene3D G3DSA:2.115.10.20 89 166 2.5E-9 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_14715 def424a7f4148383458bd8d279e05c23 345 SUPERFAMILY SSF75005 65 277 9.22E-17 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TL08_11285 e2d95d16e491d1e370550878bfc748a2 148 Pfam PF07681 DoxX 12 93 4.6E-18 T 12-10-2018 IPR032808 DoxX family TL08_24220 15a1d027c234a8b299badc98042b47ac 66 Pfam PF04149 Domain of unknown function (DUF397) 6 54 5.0E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_15050 f8bfd21d836beeb2fc285e4b671a2adf 688 Pfam PF07730 Histidine kinase 193 257 3.0E-8 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_15050 f8bfd21d836beeb2fc285e4b671a2adf 688 Gene3D G3DSA:3.30.565.10 542 674 7.3E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_15050 f8bfd21d836beeb2fc285e4b671a2adf 688 SUPERFAMILY SSF55874 553 673 6.02E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_17140 69ddefa7f3ba5ef5670f2f04a6df5947 344 SUPERFAMILY SSF81345 18 338 9.02E-77 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_17140 69ddefa7f3ba5ef5670f2f04a6df5947 344 Pfam PF01032 FecCD transport family 31 338 7.5E-90 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_17140 69ddefa7f3ba5ef5670f2f04a6df5947 344 Gene3D G3DSA:1.10.3470.10 18 341 5.7E-95 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_06210 dfc43b17284bfb73d7b2abcc9673c62c 262 SUPERFAMILY SSF52540 11 236 1.3E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_06210 dfc43b17284bfb73d7b2abcc9673c62c 262 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TL08_06210 dfc43b17284bfb73d7b2abcc9673c62c 262 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 10 249 1.5E-85 T 12-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 TL08_06210 dfc43b17284bfb73d7b2abcc9673c62c 262 Pfam PF00005 ABC transporter 25 181 2.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_06210 dfc43b17284bfb73d7b2abcc9673c62c 262 SMART SM00382 34 230 2.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_06210 dfc43b17284bfb73d7b2abcc9673c62c 262 Gene3D G3DSA:3.40.50.300 1 252 3.0E-62 T 12-10-2018 TL08_27030 6a9483be25d59f4bb9936086f05ca823 458 SUPERFAMILY SSF140459 19 178 3.14E-5 T 12-10-2018 TL08_06340 32efab471ededa6f92e09bed4277bfe9 133 SUPERFAMILY SSF88723 6 124 5.61E-14 T 12-10-2018 IPR029060 PIN-like domain superfamily TL08_06340 32efab471ededa6f92e09bed4277bfe9 133 Gene3D G3DSA:3.40.50.1010 4 133 1.1E-20 T 12-10-2018 TL08_01640 e32d5a464d633f391f09743d8f733dc0 172 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 31.963 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TL08_01640 e32d5a464d633f391f09743d8f733dc0 172 Pfam PF00719 Inorganic pyrophosphatase 5 156 2.4E-52 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TL08_01640 e32d5a464d633f391f09743d8f733dc0 172 SUPERFAMILY SSF50324 3 156 8.11E-55 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TL08_01640 e32d5a464d633f391f09743d8f733dc0 172 Gene3D G3DSA:3.90.80.10 1 161 4.8E-64 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TL08_01640 e32d5a464d633f391f09743d8f733dc0 172 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TL08_04965 03d621c795b5d4b75d7a9e8bfb74edc1 300 Gene3D G3DSA:3.30.70.3040 43 160 3.2E-35 T 12-10-2018 TL08_04965 03d621c795b5d4b75d7a9e8bfb74edc1 300 PIRSF PIRSF003097 1 300 4.8E-71 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 TL08_02785 5b25129866df0155253167677741e42f 361 SUPERFAMILY SSF101478 23 350 3.14E-40 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TL08_02785 5b25129866df0155253167677741e42f 361 Pfam PF03747 ADP-ribosylglycohydrolase 30 337 9.0E-47 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 TL08_02785 5b25129866df0155253167677741e42f 361 Gene3D G3DSA:1.10.4080.10 26 359 6.2E-48 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TL08_15745 862e3ac14cf1ec3fe22385eb86b759a1 387 Gene3D G3DSA:3.30.1870.10 66 139 3.7E-30 T 12-10-2018 TL08_15745 862e3ac14cf1ec3fe22385eb86b759a1 387 Pfam PF05139 Erythromycin esterase 67 378 8.6E-27 T 12-10-2018 IPR007815 Erythromycin esterase GO:0046677 TL08_15745 862e3ac14cf1ec3fe22385eb86b759a1 387 Gene3D G3DSA:3.40.1660.10 36 380 3.7E-30 T 12-10-2018 TL08_15745 862e3ac14cf1ec3fe22385eb86b759a1 387 Gene3D G3DSA:1.20.1440.30 140 259 3.7E-30 T 12-10-2018 TL08_15745 862e3ac14cf1ec3fe22385eb86b759a1 387 SUPERFAMILY SSF159501 13 384 5.23E-38 T 12-10-2018 TL08_04800 7cae77d83fcddb7666d02ca4176a7d78 240 SUPERFAMILY SSF56112 19 180 3.74E-12 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_04800 7cae77d83fcddb7666d02ca4176a7d78 240 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 5 235 3.9E-76 T 12-10-2018 IPR013402 Conserved hypothetical protein CHP02569 TL08_15570 974954a7a286def8ac886daac4943b9c 159 SUPERFAMILY SSF54637 15 143 5.67E-21 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_15570 974954a7a286def8ac886daac4943b9c 159 Pfam PF03061 Thioesterase superfamily 31 113 6.6E-7 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TL08_15570 974954a7a286def8ac886daac4943b9c 159 Gene3D G3DSA:3.10.129.10 8 150 1.6E-19 T 12-10-2018 TL08_26385 340d0121611ac651884dd7ec42e8a87b 215 Gene3D G3DSA:3.40.1280.10 48 214 1.0E-35 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TL08_26385 340d0121611ac651884dd7ec42e8a87b 215 Pfam PF00588 SpoU rRNA Methylase family 66 202 2.0E-25 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TL08_26385 340d0121611ac651884dd7ec42e8a87b 215 SUPERFAMILY SSF75217 49 208 2.42E-39 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TL08_26390 3bf24d386b60274a52ce30fc77b56024 398 Gene3D G3DSA:1.50.10.20 18 395 4.4E-84 T 12-10-2018 TL08_26390 3bf24d386b60274a52ce30fc77b56024 398 PIRSF PIRSF021505 15 392 1.6E-33 T 12-10-2018 IPR014512 Predicted O-glycosyl hydrolase TL08_26390 3bf24d386b60274a52ce30fc77b56024 398 SUPERFAMILY SSF48208 56 332 4.86E-32 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_26390 3bf24d386b60274a52ce30fc77b56024 398 Pfam PF03663 Glycosyl hydrolase family 76 64 355 1.7E-31 T 12-10-2018 IPR005198 Glycoside hydrolase, family 76 TL08_00360 ea169811c221bb6c2d1ee9c249b9807f 293 Pfam PF14219 Domain of unknown function (DUF4328) 101 256 2.4E-36 T 12-10-2018 IPR025565 Domain of unknown function DUF4328 TL08_02460 b62f0124f47dbcdef2dff2dc69c8d6a7 324 Pfam PF01578 Cytochrome C assembly protein 110 318 2.3E-45 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TL08_02460 b62f0124f47dbcdef2dff2dc69c8d6a7 324 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 87 321 2.7E-73 T 12-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 TL08_04900 91777b7b4bc2e1169177390f083bf6d3 438 SUPERFAMILY SSF56112 95 307 4.37E-26 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_04900 91777b7b4bc2e1169177390f083bf6d3 438 Pfam PF03109 ABC1 family 112 227 4.0E-31 T 12-10-2018 IPR004147 UbiB domain TL08_22315 aa4d922bcd99798a34f014f98f1717f8 67 Pfam PF04149 Domain of unknown function (DUF397) 9 59 3.7E-19 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_07135 9b64032504bfabb7e24cf598087ab829 73 Pfam PF12277 Protein of unknown function (DUF3618) 2 46 1.8E-16 T 12-10-2018 IPR022062 Protein of unknown function DUF3618 TL08_02135 43748d73dd8d052389a901ea04b03e74 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 299 2.9E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_02135 43748d73dd8d052389a901ea04b03e74 310 SUPERFAMILY SSF161098 66 294 7.46E-51 T 12-10-2018 IPR035906 MetI-like superfamily TL08_02135 43748d73dd8d052389a901ea04b03e74 310 Gene3D G3DSA:1.10.3720.10 62 307 3.6E-55 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23580 9c0ab3063b70a65ea635632f42be7511 105 Gene3D G3DSA:1.10.287.1060 2 97 1.4E-8 T 12-10-2018 TL08_23580 9c0ab3063b70a65ea635632f42be7511 105 SUPERFAMILY SSF140453 2 98 1.15E-8 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_24585 cab62b9eb3fc4d9629f0bd192deeda6a 244 Pfam PF17270 Family of unknown function (DUF5336) 4 152 3.2E-21 T 12-10-2018 IPR035166 Protein of unknown function DUF5336 TL08_03510 eead9aa00cf6aabaa506b1d9a6c410c6 248 Pfam PF01061 ABC-2 type transporter 7 213 3.2E-26 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_03510 eead9aa00cf6aabaa506b1d9a6c410c6 248 PIRSF PIRSF006648 1 248 1.2E-38 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_19125 f66d0cea2ab5205e17a0ec6f48838cc2 278 SMART SM01236 121 223 1.4E-20 T 12-10-2018 TL08_19125 f66d0cea2ab5205e17a0ec6f48838cc2 278 SUPERFAMILY SSF48613 82 261 6.67E-12 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_19125 f66d0cea2ab5205e17a0ec6f48838cc2 278 Pfam PF14518 Iron-containing redox enzyme 92 256 3.2E-30 T 12-10-2018 TL08_19125 f66d0cea2ab5205e17a0ec6f48838cc2 278 Gene3D G3DSA:1.20.910.10 57 268 1.1E-21 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TL08_00470 4965842eaad12193658b96a287d48049 269 Pfam PF14011 EspG family 13 259 1.3E-51 T 12-10-2018 IPR025734 EspG family TL08_04400 08d8643feb199ffd3da76b101ec0dbb7 371 SUPERFAMILY SSF89392 102 253 3.69E-11 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX TL08_04400 08d8643feb199ffd3da76b101ec0dbb7 371 Gene3D G3DSA:2.50.20.10 73 253 7.9E-17 T 12-10-2018 TL08_20365 1bb862001021c69fb624eeec6f9ea328 96 Pfam PF14019 Protein of unknown function (DUF4235) 7 83 3.2E-23 T 12-10-2018 IPR025329 Protein of unknown function DUF4235 TL08_13075 02b4197056566bedec3834c7146e9344 349 Gene3D G3DSA:1.10.3720.10 109 343 4.5E-21 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13075 02b4197056566bedec3834c7146e9344 349 SUPERFAMILY SSF161098 114 332 1.1E-14 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13075 02b4197056566bedec3834c7146e9344 349 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 347 3.4E-40 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_19280 f0eacd80c167c3a4c64e7d201781a263 162 SUPERFAMILY SSF55811 22 152 1.02E-26 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_19280 f0eacd80c167c3a4c64e7d201781a263 162 ProSitePatterns PS00893 Nudix box signature. 57 78 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_19280 f0eacd80c167c3a4c64e7d201781a263 162 Pfam PF00293 NUDIX domain 28 135 2.1E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_19280 f0eacd80c167c3a4c64e7d201781a263 162 Gene3D G3DSA:3.90.79.10 24 145 1.4E-27 T 12-10-2018 TL08_19280 f0eacd80c167c3a4c64e7d201781a263 162 PRINTS PR00502 NUDIX hydrolase family signature 66 81 2.4E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_19280 f0eacd80c167c3a4c64e7d201781a263 162 PRINTS PR00502 NUDIX hydrolase family signature 52 66 2.4E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TL08_20530 d91cd56e5cb85b6597c9ca3fc636c7f7 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 369 395 1.3E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_20530 d91cd56e5cb85b6597c9ca3fc636c7f7 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 131 150 1.3E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_20530 d91cd56e5cb85b6597c9ca3fc636c7f7 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 161 185 1.3E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_20530 d91cd56e5cb85b6597c9ca3fc636c7f7 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 317 336 1.3E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_20530 d91cd56e5cb85b6597c9ca3fc636c7f7 509 Pfam PF00361 Proton-conducting membrane transporter 126 413 3.1E-48 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_07870 60847402663248cbaeb833f3160fcbde 258 Pfam PF14011 EspG family 11 251 1.5E-60 T 12-10-2018 IPR025734 EspG family TL08_19835 8f507ac02911e2a625bdf947adc82d05 209 Pfam PF01810 LysE type translocator 17 207 2.4E-24 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TL08_15265 8d532b23aaf0bd1ddb6f928e8d7b92ff 320 Gene3D G3DSA:3.30.2350.10 83 296 2.9E-41 T 12-10-2018 TL08_15265 8d532b23aaf0bd1ddb6f928e8d7b92ff 320 SUPERFAMILY SSF55120 85 295 1.64E-47 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_15265 8d532b23aaf0bd1ddb6f928e8d7b92ff 320 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_15265 8d532b23aaf0bd1ddb6f928e8d7b92ff 320 Pfam PF00849 RNA pseudouridylate synthase 99 245 9.7E-16 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 13 557 1.4E-232 T 12-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 17 107 2.1E-16 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 SMART SM00642 169 580 9.3E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 Gene3D G3DSA:3.20.20.80 153 564 1.1E-157 T 12-10-2018 TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 Gene3D G3DSA:2.60.40.10 10 148 1.2E-36 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 Gene3D G3DSA:2.60.40.1180 650 760 1.5E-9 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 Pfam PF00128 Alpha amylase, catalytic domain 199 282 1.1E-5 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 SUPERFAMILY SSF51011 650 762 2.37E-18 T 12-10-2018 TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 SUPERFAMILY SSF51445 154 637 1.31E-122 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TL08_06580 cbb666a31743d73a3d08ba7da51325bd 772 SUPERFAMILY SSF81296 13 146 2.8E-33 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_06330 03555103ef71bd0c205ba7d9a37bd05d 395 Pfam PF05816 Toxic anion resistance protein (TelA) 64 379 2.4E-65 T 12-10-2018 IPR008863 Toxic anion resistance TL08_26625 282133a38c9511a4ea65f9c6dcecd92e 311 Pfam PF13354 Beta-lactamase enzyme family 35 271 1.3E-47 T 12-10-2018 TL08_26625 282133a38c9511a4ea65f9c6dcecd92e 311 Gene3D G3DSA:3.40.710.10 8 308 1.5E-69 T 12-10-2018 TL08_26625 282133a38c9511a4ea65f9c6dcecd92e 311 SUPERFAMILY SSF56601 12 298 8.98E-38 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_20745 2063306f0b9d28692803007b6f3e137b 106 Pfam PF05336 L-rhamnose mutarotase 4 105 2.9E-28 T 12-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 TL08_20745 2063306f0b9d28692803007b6f3e137b 106 SUPERFAMILY SSF54909 3 106 1.11E-31 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_20745 2063306f0b9d28692803007b6f3e137b 106 Gene3D G3DSA:3.30.70.100 1 97 2.1E-30 T 12-10-2018 TL08_04560 bca17b0f4fc99e004cc4027ab0084d72 446 SUPERFAMILY SSF140459 26 185 1.52E-7 T 12-10-2018 TL08_04560 bca17b0f4fc99e004cc4027ab0084d72 446 Gene3D G3DSA:1.20.1260.20 23 186 1.5E-7 T 12-10-2018 IPR038332 PPE superfamily TL08_24880 2250f07d52b216cb334c986609af6365 278 Gene3D G3DSA:3.40.50.1820 4 266 1.2E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_24880 2250f07d52b216cb334c986609af6365 278 SUPERFAMILY SSF53474 15 242 1.0E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_24880 2250f07d52b216cb334c986609af6365 278 Pfam PF12740 Chlorophyllase enzyme 31 150 4.2E-9 T 12-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 TL08_03740 39202085455c56f38986b3508659a647 343 Gene3D G3DSA:1.10.287.1080 269 343 8.5E-9 T 12-10-2018 TL08_03740 39202085455c56f38986b3508659a647 343 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 136 211 8.8E-25 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TL08_03740 39202085455c56f38986b3508659a647 343 Gene3D G3DSA:1.10.287.1080 112 238 3.9E-40 T 12-10-2018 TL08_03740 39202085455c56f38986b3508659a647 343 SUPERFAMILY SSF101386 117 215 2.94E-22 T 12-10-2018 TL08_02100 ab6b6ae78d1d31c656160272a346b630 191 Pfam PF13302 Acetyltransferase (GNAT) domain 19 155 5.5E-21 T 12-10-2018 IPR000182 GNAT domain TL08_02100 ab6b6ae78d1d31c656160272a346b630 191 Gene3D G3DSA:3.40.630.30 4 187 2.7E-46 T 12-10-2018 TL08_02100 ab6b6ae78d1d31c656160272a346b630 191 SUPERFAMILY SSF55729 12 179 4.58E-40 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_13785 d6c0d73efeeff1dc8877cd2256bf24ec 353 Gene3D G3DSA:3.40.50.1100 135 290 1.0E-42 T 12-10-2018 TL08_13785 d6c0d73efeeff1dc8877cd2256bf24ec 353 SUPERFAMILY SSF53686 28 294 6.55E-42 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TL08_13785 d6c0d73efeeff1dc8877cd2256bf24ec 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 34 275 4.8E-28 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TL08_13785 d6c0d73efeeff1dc8877cd2256bf24ec 353 Gene3D G3DSA:3.40.50.1100 29 134 1.0E-42 T 12-10-2018 TL08_08395 043a795d8bfc86f706f9d6ad3cecf078 233 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 93 181 1.8E-8 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain TL08_13130 bdfc2dd072ae39ad9283b159a777f740 188 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 180 1.5E-79 T 12-10-2018 IPR021441 Protein of unknown function DUF3090 TL08_13130 bdfc2dd072ae39ad9283b159a777f740 188 Pfam PF11290 Protein of unknown function (DUF3090) 6 176 1.9E-69 T 12-10-2018 IPR021441 Protein of unknown function DUF3090 TL08_25840 6a136e05682163b2abdbbd8debdfc8ff 325 Gene3D G3DSA:3.40.50.720 11 309 4.8E-95 T 12-10-2018 TL08_25840 6a136e05682163b2abdbbd8debdfc8ff 325 Gene3D G3DSA:3.40.50.720 100 283 4.8E-95 T 12-10-2018 TL08_25840 6a136e05682163b2abdbbd8debdfc8ff 325 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 196 218 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TL08_25840 6a136e05682163b2abdbbd8debdfc8ff 325 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 285 2.3E-53 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TL08_25840 6a136e05682163b2abdbbd8debdfc8ff 325 SUPERFAMILY SSF51735 100 286 2.19E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_25840 6a136e05682163b2abdbbd8debdfc8ff 325 SUPERFAMILY SSF52283 7 134 3.02E-27 T 12-10-2018 TL08_25840 6a136e05682163b2abdbbd8debdfc8ff 325 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 175 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TL08_25840 6a136e05682163b2abdbbd8debdfc8ff 325 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 13 317 2.1E-26 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TL08_25895 0bb2d2103be9f467f4aed92203b6f5b3 346 SUPERFAMILY SSF161098 68 335 1.44E-28 T 12-10-2018 IPR035906 MetI-like superfamily TL08_25895 0bb2d2103be9f467f4aed92203b6f5b3 346 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 44 340 4.2E-84 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 TL08_25895 0bb2d2103be9f467f4aed92203b6f5b3 346 Gene3D G3DSA:1.10.3720.10 100 340 3.6E-28 T 12-10-2018 IPR035906 MetI-like superfamily TL08_25895 0bb2d2103be9f467f4aed92203b6f5b3 346 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 337 8.8E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_20660 be6ede3708f2a184155f6a660efcba13 319 Gene3D G3DSA:1.10.3720.10 70 311 5.2E-65 T 12-10-2018 IPR035906 MetI-like superfamily TL08_20660 be6ede3708f2a184155f6a660efcba13 319 SUPERFAMILY SSF160964 32 77 1.7E-5 T 12-10-2018 TL08_20660 be6ede3708f2a184155f6a660efcba13 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 6.6E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_20660 be6ede3708f2a184155f6a660efcba13 319 SUPERFAMILY SSF161098 74 301 7.98E-53 T 12-10-2018 IPR035906 MetI-like superfamily TL08_15815 c8dcfba64bcc3338ca899fbbf5f68dfb 391 SUPERFAMILY SSF51679 6 350 8.11E-65 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_15815 c8dcfba64bcc3338ca899fbbf5f68dfb 391 Pfam PF00296 Luciferase-like monooxygenase 6 312 1.9E-39 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_15815 c8dcfba64bcc3338ca899fbbf5f68dfb 391 Gene3D G3DSA:3.20.20.30 5 352 1.5E-68 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_01975 bf1dd6fe94b26046ba3a32c302f7bef5 471 Pfam PF12821 Threonine/Serine exporter, ThrE 311 438 5.2E-15 T 12-10-2018 IPR024528 Threonine/Serine exporter, ThrE TL08_01975 bf1dd6fe94b26046ba3a32c302f7bef5 471 Pfam PF06738 Putative threonine/serine exporter 41 284 1.1E-56 T 12-10-2018 IPR010619 Putative threonine/serine exporter TL08_04245 1f354a8394a80ac407c16cda7f74b1a8 133 Gene3D G3DSA:3.40.630.30 9 132 4.8E-23 T 12-10-2018 TL08_04245 1f354a8394a80ac407c16cda7f74b1a8 133 Pfam PF00583 Acetyltransferase (GNAT) family 24 122 1.2E-14 T 12-10-2018 IPR000182 GNAT domain TL08_04245 1f354a8394a80ac407c16cda7f74b1a8 133 SUPERFAMILY SSF55729 12 126 1.91E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_03880 9d04f82bef23a14cd7f02eaf7634cb85 385 Gene3D G3DSA:3.40.640.10 2 255 4.6E-100 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TL08_03880 9d04f82bef23a14cd7f02eaf7634cb85 385 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 197 211 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TL08_03880 9d04f82bef23a14cd7f02eaf7634cb85 385 SUPERFAMILY SSF53383 14 384 9.38E-122 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TL08_03880 9d04f82bef23a14cd7f02eaf7634cb85 385 PIRSF PIRSF001434 1 385 6.5E-141 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TL08_03880 9d04f82bef23a14cd7f02eaf7634cb85 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 384 2.4E-142 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TL08_03880 9d04f82bef23a14cd7f02eaf7634cb85 385 Gene3D G3DSA:3.90.1150.10 256 385 2.8E-51 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TL08_06135 b64dccac66bc5a5ca31e6a8dab2d8578 65 Pfam PF04149 Domain of unknown function (DUF397) 8 60 1.1E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 Gene3D G3DSA:1.20.1250.20 20 464 4.5E-133 T 12-10-2018 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 25 460 6.4E-121 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 PRINTS PR00171 Sugar transporter signature 365 386 1.1E-26 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 PRINTS PR00171 Sugar transporter signature 120 139 1.1E-26 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 PRINTS PR00171 Sugar transporter signature 37 47 1.1E-26 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 PRINTS PR00171 Sugar transporter signature 388 400 1.1E-26 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 PRINTS PR00171 Sugar transporter signature 280 290 1.1E-26 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 Pfam PF00083 Sugar (and other) transporter 31 463 2.1E-123 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 SUPERFAMILY SSF103473 21 461 2.09E-82 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_19855 dc5bdeca7cf49cb0124a90f1bf88fc53 475 ProSitePatterns PS00216 Sugar transport proteins signature 1. 83 100 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TL08_25300 2b1fa0ee86122f0f51d97addaed91afd 767 Pfam PF13625 Helicase conserved C-terminal domain 471 593 6.3E-40 T 12-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 TL08_08765 53a1a86a45912ec25ae26d8b438207ae 79 Pfam PF13083 KH domain 6 66 8.6E-19 T 12-10-2018 TL08_08765 53a1a86a45912ec25ae26d8b438207ae 79 Hamap MF_00088 UPF0109 protein . 4 75 20.446 T 12-10-2018 IPR020627 Uncharacterised protein family UPF0109 TL08_08765 53a1a86a45912ec25ae26d8b438207ae 79 SUPERFAMILY SSF54814 18 61 1.11E-7 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TL08_01895 47a479eb31c47abf45bd93c958542e34 406 Pfam PF04235 Protein of unknown function (DUF418) 233 395 4.4E-36 T 12-10-2018 IPR007349 Domain of unknown function DUF418 TL08_20305 e0ca5b0eb4b70d2dd0c742b2dede7926 99 Pfam PF02467 Transcription factor WhiB 17 87 6.5E-23 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TL08_20305 e0ca5b0eb4b70d2dd0c742b2dede7926 99 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 18.641 T 12-10-2018 IPR003482 Transcription factor WhiB TL08_08795 a7485c7bad03d4a43e3ac9af1155f465 108 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 1.6E-52 T 12-10-2018 IPR019592 Protein of unknown function DUF2469 TL08_17750 289488be8b9e67cd9176237beb91b06c 416 Gene3D G3DSA:3.40.50.2000 217 395 5.7E-60 T 12-10-2018 TL08_17750 289488be8b9e67cd9176237beb91b06c 416 Gene3D G3DSA:3.40.50.2000 23 411 5.7E-60 T 12-10-2018 TL08_17750 289488be8b9e67cd9176237beb91b06c 416 SUPERFAMILY SSF53756 19 412 6.63E-66 T 12-10-2018 TL08_17750 289488be8b9e67cd9176237beb91b06c 416 Pfam PF00534 Glycosyl transferases group 1 229 394 3.4E-21 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_17750 289488be8b9e67cd9176237beb91b06c 416 Pfam PF13439 Glycosyltransferase Family 4 32 219 3.4E-19 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_07890 91f552b57a29fb972d83f4c6077ddae6 201 Pfam PF12079 Protein of unknown function (DUF3558) 17 196 9.3E-22 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 TL08_21695 78b44426367c2544093dd9ff0b9778b1 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 145 8.2E-14 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase TL08_21695 78b44426367c2544093dd9ff0b9778b1 154 SUPERFAMILY SSF55961 4 146 2.15E-28 T 12-10-2018 TL08_21695 78b44426367c2544093dd9ff0b9778b1 154 Gene3D G3DSA:3.30.530.20 3 150 1.5E-34 T 12-10-2018 IPR023393 START-like domain superfamily TL08_20285 7495297b046dbcbdb8e51c8b83f56ee7 325 SUPERFAMILY SSF49899 60 291 1.06E-23 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TL08_20285 7495297b046dbcbdb8e51c8b83f56ee7 325 Pfam PF00722 Glycosyl hydrolases family 16 96 291 2.0E-8 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 TL08_20285 7495297b046dbcbdb8e51c8b83f56ee7 325 Gene3D G3DSA:2.60.120.200 69 293 4.9E-24 T 12-10-2018 TL08_11475 9bba1729a5b368b8d3407b1c34f107b8 208 Gene3D G3DSA:3.40.50.2020 5 200 3.9E-60 T 12-10-2018 TL08_11475 9bba1729a5b368b8d3407b1c34f107b8 208 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 15 192 35.399 T 12-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TL08_11475 9bba1729a5b368b8d3407b1c34f107b8 208 SUPERFAMILY SSF53271 21 186 2.9E-39 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TL08_11475 9bba1729a5b368b8d3407b1c34f107b8 208 Pfam PF00156 Phosphoribosyl transferase domain 23 162 1.7E-18 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TL08_21680 55df6919ee4e46614658220f75a12b26 314 Pfam PF00480 ROK family 3 305 1.0E-71 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_21680 55df6919ee4e46614658220f75a12b26 314 ProSitePatterns PS01125 ROK family signature. 129 156 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TL08_21680 55df6919ee4e46614658220f75a12b26 314 SUPERFAMILY SSF53067 1 306 3.05E-61 T 12-10-2018 TL08_21680 55df6919ee4e46614658220f75a12b26 314 Gene3D G3DSA:3.30.420.40 4 300 7.8E-95 T 12-10-2018 TL08_21680 55df6919ee4e46614658220f75a12b26 314 Gene3D G3DSA:3.30.420.40 121 287 7.8E-95 T 12-10-2018 TL08_24545 205d4a3babbc2a14f49feb70ec0e1dc9 200 SUPERFAMILY SSF141571 21 197 8.63E-44 T 12-10-2018 TL08_24545 205d4a3babbc2a14f49feb70ec0e1dc9 200 Gene3D G3DSA:2.160.20.100 18 200 3.0E-56 T 12-10-2018 TL08_24545 205d4a3babbc2a14f49feb70ec0e1dc9 200 Pfam PF13599 Pentapeptide repeats (9 copies) 12 73 1.9E-7 T 12-10-2018 IPR001646 Pentapeptide repeat TL08_24545 205d4a3babbc2a14f49feb70ec0e1dc9 200 Pfam PF00805 Pentapeptide repeats (8 copies) 114 149 6.8E-10 T 12-10-2018 IPR001646 Pentapeptide repeat TL08_16395 96402d47978c0f4c268568b6680693a6 355 Pfam PF01794 Ferric reductase like transmembrane component 76 212 5.0E-11 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain TL08_02735 7d57c41d93b33b9f5bcf54b4aba28431 397 Pfam PF12704 MacB-like periplasmic core domain 31 216 4.7E-18 T 12-10-2018 IPR025857 MacB-like periplasmic core domain TL08_02735 7d57c41d93b33b9f5bcf54b4aba28431 397 Pfam PF02687 FtsX-like permease family 303 391 9.7E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TL08_18015 d714f51eab992cad9d5b286fb2817058 219 Gene3D G3DSA:3.90.79.10 12 218 7.4E-62 T 12-10-2018 TL08_18015 d714f51eab992cad9d5b286fb2817058 219 Pfam PF00293 NUDIX domain 53 166 1.9E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_18015 d714f51eab992cad9d5b286fb2817058 219 SUPERFAMILY SSF55811 17 189 7.04E-45 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_07915 84cc61548014e08e4f31ecb027cdba72 160 Gene3D G3DSA:3.10.310.50 41 156 3.2E-6 T 12-10-2018 TL08_07915 84cc61548014e08e4f31ecb027cdba72 160 Pfam PF17174 Domain of unknown function (DUF5130) 19 153 9.2E-34 T 12-10-2018 IPR033437 Protein of unknown function DUF5130 TL08_15940 42aacf89d5c4dfe9925ae5778cb61ca3 482 Pfam PF03559 NDP-hexose 2,3-dehydratase 33 235 4.3E-84 T 12-10-2018 IPR005212 NDP-hexose 2,3-dehydratase KEGG: 00523+4.2.1.159 TL08_15940 42aacf89d5c4dfe9925ae5778cb61ca3 482 Pfam PF03559 NDP-hexose 2,3-dehydratase 274 477 2.0E-73 T 12-10-2018 IPR005212 NDP-hexose 2,3-dehydratase KEGG: 00523+4.2.1.159 TL08_15940 42aacf89d5c4dfe9925ae5778cb61ca3 482 Gene3D G3DSA:3.90.79.40 84 245 1.8E-62 T 12-10-2018 IPR038153 NDP-hexose 2,3-dehydratase-like superfamily KEGG: 00523+4.2.1.159 TL08_15940 42aacf89d5c4dfe9925ae5778cb61ca3 482 Gene3D G3DSA:3.90.79.40 324 481 1.6E-55 T 12-10-2018 IPR038153 NDP-hexose 2,3-dehydratase-like superfamily KEGG: 00523+4.2.1.159 TL08_21315 500bd99cf07a5582fa6219da27acfcdd 245 PIRSF PIRSF006648 5 244 4.8E-15 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_21315 500bd99cf07a5582fa6219da27acfcdd 245 Pfam PF01061 ABC-2 type transporter 6 214 4.7E-23 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_22295 f69e458b73054eaecf8c98c94004e36a 544 Gene3D G3DSA:1.20.1730.10 22 494 5.7E-106 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily TL08_22295 f69e458b73054eaecf8c98c94004e36a 544 Pfam PF00474 Sodium:solute symporter family 33 436 8.7E-34 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TL08_22295 f69e458b73054eaecf8c98c94004e36a 544 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 436 4.0E-65 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TL08_13600 88cd0346e186b2050704e0a14c1a1cf8 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 217 1.9E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_13600 88cd0346e186b2050704e0a14c1a1cf8 220 Gene3D G3DSA:1.10.3720.10 7 220 7.3E-41 T 12-10-2018 IPR035906 MetI-like superfamily TL08_13600 88cd0346e186b2050704e0a14c1a1cf8 220 SUPERFAMILY SSF161098 10 207 1.57E-38 T 12-10-2018 IPR035906 MetI-like superfamily TL08_23670 7ddad37cec605a9a9445e41f05a073ae 74 Pfam PF04149 Domain of unknown function (DUF397) 8 60 1.1E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_18610 d704538c0034c2aa2ff20e82aabbe4af 276 Pfam PF12833 Helix-turn-helix domain 148 219 6.4E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_18610 d704538c0034c2aa2ff20e82aabbe4af 276 Gene3D G3DSA:1.10.10.60 132 221 6.0E-12 T 12-10-2018 TL08_18610 d704538c0034c2aa2ff20e82aabbe4af 276 SMART SM00342 136 218 2.5E-4 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_06705 cf2801d6304477bd99e6cac47f956012 88 SUPERFAMILY SSF47336 2 77 2.75E-11 T 12-10-2018 IPR036736 ACP-like superfamily TL08_06705 cf2801d6304477bd99e6cac47f956012 88 Pfam PF00550 Phosphopantetheine attachment site 8 65 1.6E-6 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TL08_06705 cf2801d6304477bd99e6cac47f956012 88 Gene3D G3DSA:1.10.1200.10 1 80 1.2E-10 T 12-10-2018 IPR036736 ACP-like superfamily TL08_00390 2536d9ab2c14f3392f8a1afa9d089293 619 Gene3D G3DSA:1.20.1730.10 23 232 2.8E-26 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily TL08_00390 2536d9ab2c14f3392f8a1afa9d089293 619 Gene3D G3DSA:1.20.1730.10 264 563 2.6E-18 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily TL08_00390 2536d9ab2c14f3392f8a1afa9d089293 619 Pfam PF00474 Sodium:solute symporter family 265 500 2.7E-17 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TL08_00390 2536d9ab2c14f3392f8a1afa9d089293 619 Pfam PF00474 Sodium:solute symporter family 35 197 1.8E-29 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TL08_25850 489a50892c682e4fb4acc28142e8167e 199 SUPERFAMILY SSF49329 70 197 7.85E-14 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TL08_25850 489a50892c682e4fb4acc28142e8167e 199 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 68 195 9.7E-9 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TL08_25850 489a50892c682e4fb4acc28142e8167e 199 Gene3D G3DSA:2.60.40.200 43 197 4.3E-15 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TL08_13925 56718f36b00f78f326d1c7ce8829a55b 462 Gene3D G3DSA:1.20.1250.20 19 445 2.3E-31 T 12-10-2018 TL08_13925 56718f36b00f78f326d1c7ce8829a55b 462 SUPERFAMILY SSF103473 14 449 1.7E-40 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_13925 56718f36b00f78f326d1c7ce8829a55b 462 Pfam PF11700 Vacuole effluxer Atg22 like 14 454 1.9E-94 T 12-10-2018 IPR024671 Autophagy-related protein 22-like TL08_12350 a6f0521814d2f625254b2abe66ac76a0 391 SUPERFAMILY SSF81345 60 386 2.48E-81 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_12350 a6f0521814d2f625254b2abe66ac76a0 391 Pfam PF01032 FecCD transport family 69 385 1.1E-89 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_12350 a6f0521814d2f625254b2abe66ac76a0 391 Gene3D G3DSA:1.10.3470.10 58 388 2.6E-94 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_18875 ef69a023f46efedf05670f8626d2f0db 240 Pfam PF14436 Bacterial EndoU nuclease 117 186 5.0E-7 T 12-10-2018 IPR029501 Bacterial EndoU nuclease TL08_10000 978413ac0fbd45acff71c35c0a70482d 162 Gene3D G3DSA:3.40.50.300 1 159 1.2E-16 T 12-10-2018 TL08_10000 978413ac0fbd45acff71c35c0a70482d 162 SUPERFAMILY SSF52540 1 153 3.16E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_17640 84566996f2c5bce76c080f38be2d4193 331 SUPERFAMILY SSF51658 56 236 6.91E-18 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_17640 84566996f2c5bce76c080f38be2d4193 331 Pfam PF01261 Xylose isomerase-like TIM barrel 62 223 6.7E-11 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_17640 84566996f2c5bce76c080f38be2d4193 331 Gene3D G3DSA:3.20.20.150 38 304 4.0E-21 T 12-10-2018 TL08_12205 3ed5a0c9e1cb70c64569902ec2228d94 245 Pfam PF13490 Putative zinc-finger 3 37 7.0E-8 T 12-10-2018 IPR027383 Putative zinc-finger TL08_12440 47a352ab13bee251bb652e6b0ac3ba41 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 67 329 8.5E-42 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_07015 75a356b135b2127c0bd60ba3997ab76e 175 Gene3D G3DSA:3.40.630.30 1 145 2.6E-22 T 12-10-2018 TL08_07015 75a356b135b2127c0bd60ba3997ab76e 175 Pfam PF00583 Acetyltransferase (GNAT) family 69 138 1.1E-11 T 12-10-2018 IPR000182 GNAT domain TL08_07015 75a356b135b2127c0bd60ba3997ab76e 175 SUPERFAMILY SSF55729 5 144 5.32E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_09430 f788c45497b3d7451b08d837d9edcf19 425 Pfam PF01882 Protein of unknown function DUF58 198 280 6.3E-20 T 12-10-2018 IPR002881 Domain of unknown function DUF58 TL08_12940 cee9d9b1d310fffb1b4fcb2b25279b94 165 Gene3D G3DSA:1.10.10.10 25 165 2.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12940 cee9d9b1d310fffb1b4fcb2b25279b94 165 SUPERFAMILY SSF46785 32 164 5.25E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_00095 0e2f9c889db2b68f6d9ea323de9b763a 721 Pfam PF04203 Sortase family 522 695 1.8E-27 T 12-10-2018 IPR005754 Sortase family TL08_00095 0e2f9c889db2b68f6d9ea323de9b763a 721 SUPERFAMILY SSF63817 476 697 3.61E-27 T 12-10-2018 IPR023365 Sortase domain superfamily TL08_00425 09bf0ff22c54e61f8f4f383ff0a96b7f 270 SUPERFAMILY SSF51695 3 258 9.42E-61 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_00425 09bf0ff22c54e61f8f4f383ff0a96b7f 270 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 253 2.6E-36 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TL08_00425 09bf0ff22c54e61f8f4f383ff0a96b7f 270 Gene3D G3DSA:3.20.20.190 1 265 1.4E-64 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_24775 bcf1818ba0c739be0ffe3aec8d42cd3c 126 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 6 119 2.0E-22 T 12-10-2018 IPR035165 Protein of unknown function DUF5319 TL08_24775 bcf1818ba0c739be0ffe3aec8d42cd3c 126 Pfam PF17252 Family of unknown function (DUF5319) 3 121 1.0E-48 T 12-10-2018 IPR035165 Protein of unknown function DUF5319 TL08_13710 6118f60ff94c104d616afa47512a35f5 346 Gene3D G3DSA:1.10.3470.10 21 345 4.7E-83 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_13710 6118f60ff94c104d616afa47512a35f5 346 SUPERFAMILY SSF81345 18 341 2.22E-70 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TL08_13710 6118f60ff94c104d616afa47512a35f5 346 Pfam PF01032 FecCD transport family 36 341 2.7E-79 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TL08_02565 0317bea9b909c6c65ca2f6ab68835571 111 Gene3D G3DSA:3.10.20.520 16 81 1.1E-30 T 12-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B TL08_02565 0317bea9b909c6c65ca2f6ab68835571 111 Pfam PF06243 Phenylacetic acid degradation B 22 107 9.5E-38 T 12-10-2018 IPR009359 Phenylacetic acid degradation B TL08_02565 0317bea9b909c6c65ca2f6ab68835571 111 PIRSF PIRSF030200 8 111 6.0E-42 T 12-10-2018 IPR009359 Phenylacetic acid degradation B TL08_02565 0317bea9b909c6c65ca2f6ab68835571 111 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 22 110 1.1E-41 T 12-10-2018 IPR009359 Phenylacetic acid degradation B TL08_13140 fd5b226dc71b3ca0b78fd9049dcb974c 152 SUPERFAMILY SSF53927 7 133 4.68E-25 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TL08_13140 fd5b226dc71b3ca0b78fd9049dcb974c 152 Gene3D G3DSA:3.40.140.10 1 143 4.1E-27 T 12-10-2018 TL08_13140 fd5b226dc71b3ca0b78fd9049dcb974c 152 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 7 108 8.1E-16 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TL08_16365 3e9a0fc354e40057c40bbe2c6470596e 434 SUPERFAMILY SSF55874 324 430 1.02E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_16365 3e9a0fc354e40057c40bbe2c6470596e 434 Gene3D G3DSA:3.30.565.10 309 429 1.6E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_16365 3e9a0fc354e40057c40bbe2c6470596e 434 Pfam PF07730 Histidine kinase 236 308 2.3E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_16365 3e9a0fc354e40057c40bbe2c6470596e 434 Pfam PF13796 Putative sensor 31 208 2.9E-13 T 12-10-2018 IPR025828 Putative sensor domain TL08_26295 57166158733bb2adc3c461b5cc49de7e 328 Pfam PF00005 ABC transporter 18 154 4.8E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TL08_26295 57166158733bb2adc3c461b5cc49de7e 328 SUPERFAMILY SSF52540 2 229 1.46E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_26295 57166158733bb2adc3c461b5cc49de7e 328 Gene3D G3DSA:3.40.50.300 1 228 2.0E-50 T 12-10-2018 TL08_26295 57166158733bb2adc3c461b5cc49de7e 328 SMART SM00382 26 204 2.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TL08_05755 26ab3bd6c962390ba586250175c9afa0 381 Pfam PF12698 ABC-2 family transporter protein 24 370 4.0E-34 T 12-10-2018 TL08_15545 77f7da7947320cd828da96105cb8adba 185 Pfam PF14015 Protein of unknown function (DUF4231) 51 135 1.5E-8 T 12-10-2018 IPR025325 Protein of unknown function DUF4231 TL08_17355 eff8b644bd6259afc7a53b19feea900f 554 SUPERFAMILY SSF53756 142 306 1.73E-5 T 12-10-2018 TL08_01080 d807086ad8f4bc8035d0e1f74df068b4 231 SUPERFAMILY SSF52540 55 212 8.67E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_01080 d807086ad8f4bc8035d0e1f74df068b4 231 Gene3D G3DSA:3.40.50.300 35 216 1.9E-21 T 12-10-2018 TL08_01080 d807086ad8f4bc8035d0e1f74df068b4 231 Pfam PF02224 Cytidylate kinase 56 77 1.2E-4 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TL08_19530 11c989a40c199a1ae4ac6c898b9e989b 202 SUPERFAMILY SSF52218 5 190 6.14E-23 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_19530 11c989a40c199a1ae4ac6c898b9e989b 202 Gene3D G3DSA:3.40.50.360 7 199 5.9E-17 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TL08_19530 11c989a40c199a1ae4ac6c898b9e989b 202 Pfam PF03358 NADPH-dependent FMN reductase 7 157 6.3E-20 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TL08_23360 67d16d99b7c0c0d78ed96dc65487e4b6 115 SUPERFAMILY SSF55486 1 112 3.66E-20 T 12-10-2018 TL08_23360 67d16d99b7c0c0d78ed96dc65487e4b6 115 Pfam PF06262 Zincin-like metallopeptidase 18 111 1.9E-10 T 12-10-2018 IPR010428 Zincin-like metallopeptidase TL08_23360 67d16d99b7c0c0d78ed96dc65487e4b6 115 Gene3D G3DSA:3.30.2010.20 1 113 6.7E-10 T 12-10-2018 IPR038555 Zincin-like metallopeptidase superfamily TL08_00615 4cc8838249278072afbff966c982b8f3 116 SUPERFAMILY SSF55486 3 115 3.47E-37 T 12-10-2018 TL08_00615 4cc8838249278072afbff966c982b8f3 116 Gene3D G3DSA:3.30.2010.20 1 115 1.3E-41 T 12-10-2018 IPR038555 Zincin-like metallopeptidase superfamily TL08_00615 4cc8838249278072afbff966c982b8f3 116 Pfam PF06262 Zincin-like metallopeptidase 29 115 6.1E-33 T 12-10-2018 IPR010428 Zincin-like metallopeptidase TL08_18000 b326330c61056cb499e01838c37717d8 382 SUPERFAMILY SSF53474 225 320 7.58E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18000 b326330c61056cb499e01838c37717d8 382 Pfam PF06259 Alpha/beta hydrolase 137 309 1.1E-42 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 TL08_26580 8bc75624dbbb5f225891fb607a1b7038 265 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 137 8.3E-10 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TL08_26580 8bc75624dbbb5f225891fb607a1b7038 265 Gene3D G3DSA:1.10.1040.10 141 265 3.8E-29 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TL08_26580 8bc75624dbbb5f225891fb607a1b7038 265 PIRSF PIRSF000103 1 264 6.6E-20 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TL08_26580 8bc75624dbbb5f225891fb607a1b7038 265 Gene3D G3DSA:3.40.50.720 1 139 1.0E-23 T 12-10-2018 TL08_26580 8bc75624dbbb5f225891fb607a1b7038 265 SUPERFAMILY SSF51735 1 140 4.24E-16 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_21450 dc0432a7dd0b7134f724ce7254759be4 301 SUPERFAMILY SSF161098 93 281 3.27E-31 T 12-10-2018 IPR035906 MetI-like superfamily TL08_21450 dc0432a7dd0b7134f724ce7254759be4 301 Gene3D G3DSA:1.10.3720.10 93 291 4.0E-28 T 12-10-2018 IPR035906 MetI-like superfamily TL08_21450 dc0432a7dd0b7134f724ce7254759be4 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 283 3.8E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_20500 a8f1d43a2c82a6c1deda46104bbbfeac 523 Pfam PF08386 TAP-like protein 424 521 6.7E-19 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal TL08_20500 a8f1d43a2c82a6c1deda46104bbbfeac 523 SUPERFAMILY SSF53474 117 494 1.52E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_22760 53cb232cecf4a4c1c97e569d7237bcaf 66 Pfam PF04149 Domain of unknown function (DUF397) 13 64 2.3E-20 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_21545 f8ae7195f33f0a276b5f68f0fb46ced7 227 Pfam PF11353 Protein of unknown function (DUF3153) 39 217 2.2E-8 T 12-10-2018 IPR021499 Protein of unknown function DUF3153 TL08_07380 88d13277b332266698a7000c0ea264c8 249 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 2 244 4.1E-66 T 12-10-2018 IPR014337 Ectoine/Hydroxyectoine ABC transporter, substrate-binding protein EhuB GO:0033294|GO:0051470 TL08_07380 88d13277b332266698a7000c0ea264c8 249 SMART SM00062 1 232 9.7E-26 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_07380 88d13277b332266698a7000c0ea264c8 249 SUPERFAMILY SSF53850 3 226 8.1E-35 T 12-10-2018 TL08_07380 88d13277b332266698a7000c0ea264c8 249 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 3 224 9.6E-34 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TL08_07380 88d13277b332266698a7000c0ea264c8 249 Gene3D G3DSA:3.40.190.10 5 226 4.4E-59 T 12-10-2018 TL08_07380 88d13277b332266698a7000c0ea264c8 249 Gene3D G3DSA:3.40.190.10 84 190 4.4E-59 T 12-10-2018 TL08_08165 c957e6dce7ad47e7f2ff6549cee50a1e 438 Gene3D G3DSA:3.40.190.10 89 368 3.6E-36 T 12-10-2018 TL08_08165 c957e6dce7ad47e7f2ff6549cee50a1e 438 SUPERFAMILY SSF53850 37 404 1.54E-36 T 12-10-2018 TL08_08165 c957e6dce7ad47e7f2ff6549cee50a1e 438 Pfam PF01547 Bacterial extracellular solute-binding protein 88 335 2.7E-11 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TL08_08165 c957e6dce7ad47e7f2ff6549cee50a1e 438 Gene3D G3DSA:3.40.190.10 143 404 3.6E-36 T 12-10-2018 TL08_16045 c5724bbbbc2aa2718002ab0c038b6c2b 284 Pfam PF13460 NAD(P)H-binding 10 180 2.6E-24 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_16045 c5724bbbbc2aa2718002ab0c038b6c2b 284 SUPERFAMILY SSF51735 5 252 1.71E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_16045 c5724bbbbc2aa2718002ab0c038b6c2b 284 Gene3D G3DSA:3.90.25.10 135 264 9.0E-72 T 12-10-2018 TL08_16045 c5724bbbbc2aa2718002ab0c038b6c2b 284 Gene3D G3DSA:3.40.50.720 7 263 9.0E-72 T 12-10-2018 TL08_16525 685f4e944451fe71d94c094aa1112c6c 218 SUPERFAMILY SSF46689 6 75 7.7E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16525 685f4e944451fe71d94c094aa1112c6c 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 2.1E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16525 685f4e944451fe71d94c094aa1112c6c 218 Gene3D G3DSA:1.10.357.10 5 195 1.7E-24 T 12-10-2018 TL08_16525 685f4e944451fe71d94c094aa1112c6c 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 7.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16525 685f4e944451fe71d94c094aa1112c6c 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 7.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_21690 4ed3702a2809f28d0bd5eda2c538ff66 399 Gene3D G3DSA:3.40.50.300 1 315 4.0E-78 T 12-10-2018 TL08_21690 4ed3702a2809f28d0bd5eda2c538ff66 399 Gene3D G3DSA:2.60.40.790 325 394 2.5E-15 T 12-10-2018 IPR008978 HSP20-like chaperone TL08_21690 4ed3702a2809f28d0bd5eda2c538ff66 399 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 5 297 3.0E-54 T 12-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 TL08_21690 4ed3702a2809f28d0bd5eda2c538ff66 399 SUPERFAMILY SSF52540 4 275 5.26E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_21690 4ed3702a2809f28d0bd5eda2c538ff66 399 Pfam PF02374 Anion-transporting ATPase 2 304 6.2E-62 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 TL08_21645 f55228daf4b1bcae5be553012b961770 206 Pfam PF14436 Bacterial EndoU nuclease 142 202 1.0E-5 T 12-10-2018 IPR029501 Bacterial EndoU nuclease TL08_09975 a58d92b9b1a02d4358d04ba49e6df3d1 204 Pfam PF01810 LysE type translocator 15 200 6.5E-19 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TL08_19405 8990bed5d863e4c4153a687c98caa861 330 SUPERFAMILY SSF53474 33 313 5.81E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_19405 8990bed5d863e4c4153a687c98caa861 330 Pfam PF12697 Alpha/beta hydrolase family 57 310 1.1E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_19405 8990bed5d863e4c4153a687c98caa861 330 Gene3D G3DSA:3.40.50.1820 31 314 2.3E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16615 6e1e4a10bd2e03795824807378c4b03d 342 PRINTS PR00412 Epoxide hydrolase signature 87 105 4.2E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16615 6e1e4a10bd2e03795824807378c4b03d 342 PRINTS PR00412 Epoxide hydrolase signature 151 164 4.2E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16615 6e1e4a10bd2e03795824807378c4b03d 342 PRINTS PR00412 Epoxide hydrolase signature 317 339 4.2E-11 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 TL08_16615 6e1e4a10bd2e03795824807378c4b03d 342 SUPERFAMILY SSF53474 56 341 4.83E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16615 6e1e4a10bd2e03795824807378c4b03d 342 Gene3D G3DSA:3.40.50.1820 59 341 2.0E-77 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_16615 6e1e4a10bd2e03795824807378c4b03d 342 Pfam PF00561 alpha/beta hydrolase fold 82 170 9.8E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_12495 ca0fd4f2ea5f3aaafb9c8582041b8fdd 295 Pfam PF03747 ADP-ribosylglycohydrolase 13 271 8.2E-47 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 TL08_12495 ca0fd4f2ea5f3aaafb9c8582041b8fdd 295 Gene3D G3DSA:1.10.4080.10 5 288 4.1E-58 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TL08_12495 ca0fd4f2ea5f3aaafb9c8582041b8fdd 295 SUPERFAMILY SSF101478 8 280 2.22E-51 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily TL08_01765 4362a7836926aa50c626917edd8ce00a 174 Gene3D G3DSA:3.90.1140.10 3 161 1.8E-6 T 12-10-2018 TL08_03480 e471cf0394b20e1569baf5ec10e57977 392 Pfam PF04235 Protein of unknown function (DUF418) 225 390 5.3E-30 T 12-10-2018 IPR007349 Domain of unknown function DUF418 TL08_25620 08e771b80da7ccde1833a825ede989d2 404 SUPERFAMILY SSF53756 2 348 5.78E-15 T 12-10-2018 TL08_25620 08e771b80da7ccde1833a825ede989d2 404 Pfam PF13579 Glycosyl transferase 4-like domain 17 231 2.0E-8 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TL08_25620 08e771b80da7ccde1833a825ede989d2 404 Pfam PF13692 Glycosyl transferases group 1 248 376 1.4E-10 T 12-10-2018 TL08_21840 785c4d16a7a02044a1c81c0f9bea5692 366 Gene3D G3DSA:3.30.470.10 30 361 5.3E-135 T 12-10-2018 TL08_21840 785c4d16a7a02044a1c81c0f9bea5692 366 Gene3D G3DSA:3.20.10.10 176 348 5.3E-135 T 12-10-2018 TL08_21840 785c4d16a7a02044a1c81c0f9bea5692 366 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 362 4.8E-131 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 TL08_21840 785c4d16a7a02044a1c81c0f9bea5692 366 Pfam PF01063 Amino-transferase class IV 75 320 4.6E-31 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TL08_21840 785c4d16a7a02044a1c81c0f9bea5692 366 SUPERFAMILY SSF56752 11 362 2.35E-111 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TL08_21840 785c4d16a7a02044a1c81c0f9bea5692 366 PIRSF PIRSF006468 5 365 1.6E-127 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 TL08_00510 26fc31aa99e7ac5caec68a8c4a722ef7 210 Pfam PF10517 Electron transfer DM13 105 207 8.4E-24 T 12-10-2018 IPR019545 DM13 domain TL08_12405 6547567ee6117ea07ea9c9af443da44f 82 Gene3D G3DSA:1.20.1530.10 3 63 6.0E-15 T 12-10-2018 IPR023171 Na/H antiporter domain superfamily TL08_12405 6547567ee6117ea07ea9c9af443da44f 82 Pfam PF06965 Na+/H+ antiporter 1 6 55 2.5E-13 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TL08_25735 3cba755620a3d26d623fc088b8431602 129 Pfam PF12986 Domain of unknown function (DUF3870) 24 112 1.9E-21 T 12-10-2018 IPR024617 Domain of unknown function DUF3870 TL08_07060 c31c5bc3c5fe909c034b79b4786c7b2e 540 SUPERFAMILY SSF52540 83 307 3.94E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_07060 c31c5bc3c5fe909c034b79b4786c7b2e 540 Gene3D G3DSA:3.40.50.300 74 273 2.1E-5 T 12-10-2018 TL08_07060 c31c5bc3c5fe909c034b79b4786c7b2e 540 Pfam PF13191 AAA ATPase domain 85 222 1.5E-8 T 12-10-2018 TL08_04650 41f9dd83ba025d03cfbf8717b67f36ae 286 Pfam PF13490 Putative zinc-finger 15 45 2.7E-5 T 12-10-2018 IPR027383 Putative zinc-finger TL08_21665 2d5167276978075713f255265cab2dc0 252 Pfam PF01553 Acyltransferase 21 151 1.2E-26 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_21665 2d5167276978075713f255265cab2dc0 252 SMART SM00563 35 154 1.8E-36 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_21665 2d5167276978075713f255265cab2dc0 252 SUPERFAMILY SSF69593 2 226 2.62E-54 T 12-10-2018 TL08_04790 81751e24e54d264cd02e2bc789747d74 350 SUPERFAMILY SSF55486 214 331 1.33E-10 T 12-10-2018 TL08_04790 81751e24e54d264cd02e2bc789747d74 350 Pfam PF11350 Protein of unknown function (DUF3152) 142 350 2.6E-65 T 12-10-2018 IPR022603 Domain of unknown function DUF3152 TL08_02585 837b85089d754dbec9071d0edc7588b6 385 SUPERFAMILY SSF53474 46 335 8.67E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_02585 837b85089d754dbec9071d0edc7588b6 385 Pfam PF12146 Serine aminopeptidase, S33 115 212 1.8E-6 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 TL08_02585 837b85089d754dbec9071d0edc7588b6 385 Gene3D G3DSA:3.40.50.1820 44 345 1.0E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_19395 20c8bfaff66f56742ed6e30597ccc8d1 632 Gene3D G3DSA:2.115.10.10 122 278 1.1E-26 T 12-10-2018 TL08_19395 20c8bfaff66f56742ed6e30597ccc8d1 632 SUPERFAMILY SSF50934 123 234 3.27E-14 T 12-10-2018 IPR036813 Tachylectin 2 superfamily TL08_19395 20c8bfaff66f56742ed6e30597ccc8d1 632 SUPERFAMILY SSF89372 390 603 1.57E-16 T 12-10-2018 TL08_19395 20c8bfaff66f56742ed6e30597ccc8d1 632 Pfam PF14517 Tachylectin 38 244 5.6E-27 T 12-10-2018 IPR023294 Tachylectin 2 TL08_26395 c4f8a3a0abf99b9ea3fae827547f2a79 185 SUPERFAMILY SSF109854 75 162 1.19E-6 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_26395 c4f8a3a0abf99b9ea3fae827547f2a79 185 Gene3D G3DSA:1.20.120.450 15 176 8.1E-6 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TL08_26395 c4f8a3a0abf99b9ea3fae827547f2a79 185 Pfam PF12867 DinB superfamily 22 173 5.8E-20 T 12-10-2018 IPR024775 DinB-like domain TL08_21505 7341ff48a801bdcfb36ce7875af7111a 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 2.9E-29 T 12-10-2018 IPR021408 Protein of unknown function DUF3046 TL08_20720 3ecd2902fdf82f3194fdf10933c81023 96 Gene3D G3DSA:3.40.190.10 1 42 1.3E-18 T 12-10-2018 TL08_20720 3ecd2902fdf82f3194fdf10933c81023 96 Gene3D G3DSA:3.40.190.10 43 86 1.3E-18 T 12-10-2018 TL08_00685 790b9c454256cebec7261a7d2dc90b66 294 Gene3D G3DSA:3.90.550.10 2 253 3.0E-27 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00685 790b9c454256cebec7261a7d2dc90b66 294 SUPERFAMILY SSF53448 3 235 3.56E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_00685 790b9c454256cebec7261a7d2dc90b66 294 Pfam PF00535 Glycosyl transferase family 2 5 117 1.8E-16 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TL08_21495 2985bb1cb8eee2a2418b5627a4596f29 282 Pfam PF14325 Domain of unknown function (DUF4383) 18 132 3.1E-8 T 12-10-2018 IPR025492 Protein of unknown function DUF4383 TL08_09585 2c0397bb04309be2f14ecb1382b149fa 172 Pfam PF03703 Bacterial PH domain 82 150 1.7E-15 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_09960 a84beeab6163176089e313b64d953a2c 284 Gene3D G3DSA:2.70.70.10 30 173 1.3E-34 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_09960 a84beeab6163176089e313b64d953a2c 284 Pfam PF01551 Peptidase family M23 58 150 2.5E-25 T 12-10-2018 IPR016047 Peptidase M23 TL08_09960 a84beeab6163176089e313b64d953a2c 284 SUPERFAMILY SSF51261 68 150 5.13E-30 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_24235 267426f620652bb52a62ce46edcd483a 71 Pfam PF04149 Domain of unknown function (DUF397) 15 66 1.2E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_24150 80776a0c044d32033bf84d293ada2467 151 SUPERFAMILY SSF54637 15 143 2.2E-26 T 12-10-2018 IPR029069 HotDog domain superfamily TL08_24150 80776a0c044d32033bf84d293ada2467 151 Pfam PF01575 MaoC like domain 20 113 9.3E-23 T 12-10-2018 IPR002539 MaoC-like dehydratase domain TL08_24150 80776a0c044d32033bf84d293ada2467 151 PRINTS PR01483 Fatty acid synthase signature 53 74 7.5E-5 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 TL08_24150 80776a0c044d32033bf84d293ada2467 151 PRINTS PR01483 Fatty acid synthase signature 31 53 7.5E-5 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 TL08_24150 80776a0c044d32033bf84d293ada2467 151 Gene3D G3DSA:3.10.129.10 8 146 2.8E-38 T 12-10-2018 TL08_19140 457ae96b956e679f20ad47d2080e0826 332 SUPERFAMILY SSF103481 228 331 2.09E-5 T 12-10-2018 TL08_19140 457ae96b956e679f20ad47d2080e0826 332 Pfam PF04657 Putative inner membrane exporter, YdcZ 186 328 7.1E-38 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ TL08_19140 457ae96b956e679f20ad47d2080e0826 332 Pfam PF04657 Putative inner membrane exporter, YdcZ 6 141 2.8E-29 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ TL08_00305 df5732bd76bedb8a991b16acc1cae9e8 416 Pfam PF01757 Acyltransferase family 61 382 7.0E-21 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_07825 44c6a3accdc2525d65cfb55bcf720422 160 Pfam PF00436 Single-strand binding protein family 6 104 1.2E-11 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TL08_07825 44c6a3accdc2525d65cfb55bcf720422 160 Gene3D G3DSA:2.40.50.140 1 117 1.6E-28 T 12-10-2018 TL08_07825 44c6a3accdc2525d65cfb55bcf720422 160 SUPERFAMILY SSF50249 6 130 5.43E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TL08_07720 e0598206790cf3d88ca7c3ce68fe1063 341 SUPERFAMILY SSF51679 7 330 4.45E-71 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_07720 e0598206790cf3d88ca7c3ce68fe1063 341 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 8 331 2.2E-119 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 TL08_07720 e0598206790cf3d88ca7c3ce68fe1063 341 Pfam PF00296 Luciferase-like monooxygenase 10 307 5.3E-37 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_07720 e0598206790cf3d88ca7c3ce68fe1063 341 Gene3D G3DSA:3.20.20.30 3 336 6.4E-100 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_17910 08808246183b9dfbaa6e8c8ee04309d6 412 Pfam PF00999 Sodium/hydrogen exchanger family 16 372 4.8E-43 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TL08_17910 08808246183b9dfbaa6e8c8ee04309d6 412 Gene3D G3DSA:1.20.1530.20 5 383 1.7E-51 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TL08_10405 9ffc7463e4b0b1320fbd8743983be137 165 Pfam PF14081 Domain of unknown function (DUF4262) 16 138 4.9E-36 T 12-10-2018 IPR025358 Protein of unknown function DUF4262 TL08_06495 9fe1dfd51c4cfe9375c4202e32c8462f 92 Gene3D G3DSA:3.10.20.30 1 90 1.2E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TL08_06495 9fe1dfd51c4cfe9375c4202e32c8462f 92 Pfam PF02597 ThiS family 5 90 3.4E-19 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TL08_06495 9fe1dfd51c4cfe9375c4202e32c8462f 92 SUPERFAMILY SSF54285 1 90 9.16E-24 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TL08_03240 e278a2c6907dd73c7189563458d9168c 76 Pfam PF14013 MT0933-like antitoxin protein 5 62 2.7E-6 T 12-10-2018 IPR028037 Antitoxin Rv0909/MT0933 TL08_26830 d2bf62d4f6f456187c97b2ec11399977 508 PIRSF PIRSF010361 4 464 1.1E-73 T 12-10-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane TL08_17935 339ad94708f4a90a8691f4a58fdc8103 359 SUPERFAMILY SSF56601 64 322 1.34E-14 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_17935 339ad94708f4a90a8691f4a58fdc8103 359 Pfam PF13354 Beta-lactamase enzyme family 71 280 1.8E-14 T 12-10-2018 TL08_17935 339ad94708f4a90a8691f4a58fdc8103 359 Gene3D G3DSA:3.40.710.10 54 333 3.3E-28 T 12-10-2018 TL08_02180 0c1a68ca983583f128d94860b78ccb4c 135 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 12 120 1.4E-21 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TL08_02180 0c1a68ca983583f128d94860b78ccb4c 135 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 10 125 17.541 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TL08_21925 fb8635fd6c2d9166e9c6f4abc147ae87 126 Pfam PF01638 HxlR-like helix-turn-helix 32 112 2.2E-21 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_21925 fb8635fd6c2d9166e9c6f4abc147ae87 126 Gene3D G3DSA:1.10.10.10 8 124 1.5E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_21925 fb8635fd6c2d9166e9c6f4abc147ae87 126 SUPERFAMILY SSF46785 17 118 2.0E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_05135 e7ff5742cc710446afc314fa689cd46a 401 Gene3D G3DSA:3.30.565.10 281 400 7.8E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_05135 e7ff5742cc710446afc314fa689cd46a 401 Pfam PF07730 Histidine kinase 215 280 8.0E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_05135 e7ff5742cc710446afc314fa689cd46a 401 SUPERFAMILY SSF55874 286 399 5.48E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_00950 69422ad7e629f504c650eeada26b3c94 468 Pfam PF01566 Natural resistance-associated macrophage protein 57 398 9.8E-18 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TL08_00755 7d7be4f0eaaba42b6dfdee3b32145f5f 143 Gene3D G3DSA:1.10.10.10 1 142 8.8E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_00755 7d7be4f0eaaba42b6dfdee3b32145f5f 143 SUPERFAMILY SSF46785 4 139 1.22E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_00755 7d7be4f0eaaba42b6dfdee3b32145f5f 143 Pfam PF12802 MarR family 27 87 3.9E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00755 7d7be4f0eaaba42b6dfdee3b32145f5f 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 5.1E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00755 7d7be4f0eaaba42b6dfdee3b32145f5f 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 5.1E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00755 7d7be4f0eaaba42b6dfdee3b32145f5f 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 5.1E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00755 7d7be4f0eaaba42b6dfdee3b32145f5f 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 5.1E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00755 7d7be4f0eaaba42b6dfdee3b32145f5f 143 SMART SM00347 21 124 1.8E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_11240 f45f97e02a8e6d41e1c87f668463e083 381 Pfam PF00676 Dehydrogenase E1 component 60 356 1.0E-80 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TL08_11240 f45f97e02a8e6d41e1c87f668463e083 381 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 52 365 3.5E-129 T 12-10-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 TL08_11240 f45f97e02a8e6d41e1c87f668463e083 381 SUPERFAMILY SSF52518 49 367 2.14E-98 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TL08_11240 f45f97e02a8e6d41e1c87f668463e083 381 Gene3D G3DSA:3.40.50.970 10 374 2.2E-120 T 12-10-2018 TL08_25210 9b4a9a418e780fd01a49b556bc20d49a 1042 SUPERFAMILY SSF55874 53 145 8.86E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_17345 0b7f44598a050e93d3885f7ee9f37a67 344 SUPERFAMILY SSF141571 189 253 1.44E-6 T 12-10-2018 TL08_17345 0b7f44598a050e93d3885f7ee9f37a67 344 Gene3D G3DSA:2.160.20.80 188 279 4.8E-7 T 12-10-2018 TL08_17345 0b7f44598a050e93d3885f7ee9f37a67 344 Pfam PF13576 Pentapeptide repeats (9 copies) 202 247 5.2E-10 T 12-10-2018 IPR001646 Pentapeptide repeat TL08_04870 49e079ba8e2a6dbd5c3f63f13fc23042 308 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 138 168 3.7E-12 T 12-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 TL08_04870 49e079ba8e2a6dbd5c3f63f13fc23042 308 Gene3D G3DSA:3.90.79.10 171 308 3.8E-34 T 12-10-2018 TL08_04870 49e079ba8e2a6dbd5c3f63f13fc23042 308 Pfam PF00293 NUDIX domain 172 282 2.4E-18 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_04870 49e079ba8e2a6dbd5c3f63f13fc23042 308 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 77 135 6.3E-6 T 12-10-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 TL08_04870 49e079ba8e2a6dbd5c3f63f13fc23042 308 Gene3D G3DSA:3.90.79.20 61 169 5.8E-12 T 12-10-2018 TL08_04870 49e079ba8e2a6dbd5c3f63f13fc23042 308 SUPERFAMILY SSF55811 122 306 1.14E-46 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_04870 49e079ba8e2a6dbd5c3f63f13fc23042 308 ProSitePatterns PS00893 Nudix box signature. 204 225 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TL08_22620 e6994301c5627f0a6f0adced20f98f08 269 Pfam PF01553 Acyltransferase 42 168 8.1E-28 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_22620 e6994301c5627f0a6f0adced20f98f08 269 SUPERFAMILY SSF69593 41 235 3.4E-45 T 12-10-2018 TL08_22620 e6994301c5627f0a6f0adced20f98f08 269 SMART SM00563 54 172 9.5E-36 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TL08_19990 a6be969c4274497cf0cec14268de1de9 125 Pfam PF05331 Protein of unknown function (DUF742) 13 125 1.1E-29 T 12-10-2018 IPR007995 Protein of unknown function DUF742 TL08_00995 b8f3192846165d6bfd0eaa6036d28207 275 SMART SM00530 6 61 4.9E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_00995 b8f3192846165d6bfd0eaa6036d28207 275 Gene3D G3DSA:1.10.260.40 1 63 9.3E-7 T 12-10-2018 TL08_00995 b8f3192846165d6bfd0eaa6036d28207 275 SUPERFAMILY SSF47413 3 59 2.04E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_00995 b8f3192846165d6bfd0eaa6036d28207 275 Pfam PF13560 Helix-turn-helix domain 3 62 3.6E-7 T 12-10-2018 TL08_05455 f72e084747fe37bb413d6f9f2689a8d4 107 Gene3D G3DSA:1.10.287.1060 3 102 7.0E-10 T 12-10-2018 TL08_05455 f72e084747fe37bb413d6f9f2689a8d4 107 SUPERFAMILY SSF140453 5 102 3.79E-6 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_24780 142ccb31b3607a4c35557046bd74b61e 314 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 33 79 6.7E-12 T 12-10-2018 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region TL08_08025 58a999afa823ecfa273887686db8bb4c 203 Gene3D G3DSA:1.10.357.10 8 194 1.7E-21 T 12-10-2018 TL08_08025 58a999afa823ecfa273887686db8bb4c 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 5.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_08025 58a999afa823ecfa273887686db8bb4c 203 SUPERFAMILY SSF46689 12 70 4.02E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_15280 441a6ce86d95c6b149fae2f8f4e4f160 258 Pfam PF12697 Alpha/beta hydrolase family 23 249 3.3E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_15280 441a6ce86d95c6b149fae2f8f4e4f160 258 Gene3D G3DSA:3.40.50.1820 1 257 4.8E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15280 441a6ce86d95c6b149fae2f8f4e4f160 258 SUPERFAMILY SSF53474 2 257 1.97E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_09590 fde3c4bb27d6b0cfb9034ba9f225b901 539 PIRSF PIRSF026631 36 528 1.6E-51 T 12-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 TL08_09590 fde3c4bb27d6b0cfb9034ba9f225b901 539 Pfam PF03703 Bacterial PH domain 86 167 8.7E-9 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_17785 6fe4e47167387c6b9cfd1fa00994cee5 296 Gene3D G3DSA:2.70.70.10 140 291 3.4E-47 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_17785 6fe4e47167387c6b9cfd1fa00994cee5 296 SUPERFAMILY SSF51261 86 288 5.75E-53 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_17785 6fe4e47167387c6b9cfd1fa00994cee5 296 Pfam PF01551 Peptidase family M23 190 284 5.3E-33 T 12-10-2018 IPR016047 Peptidase M23 TL08_21130 a7ac0c6b23023367f66e626693df0e9e 526 SUPERFAMILY SSF53474 109 321 1.22E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_21130 a7ac0c6b23023367f66e626693df0e9e 526 Pfam PF00561 alpha/beta hydrolase fold 112 498 1.1E-38 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TL08_22965 3f38ec9731538e7a0ea7b43c0acb2bba 132 Pfam PF02656 Domain of unknown function (DUF202) 33 96 2.5E-14 T 12-10-2018 IPR003807 Domain of unknown function DUF202 TL08_06600 c80c3005bcb9b6232909f534de4cb068 183 Pfam PF02575 YbaB/EbfC DNA-binding family 28 115 4.5E-12 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_06600 c80c3005bcb9b6232909f534de4cb068 183 SUPERFAMILY SSF82607 31 117 1.23E-8 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_06600 c80c3005bcb9b6232909f534de4cb068 183 Gene3D G3DSA:3.30.1310.10 22 124 6.5E-11 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_05875 b1b8208a130f4b0a9d9b26fcf6a2177e 484 Gene3D G3DSA:3.30.9.10 106 342 7.7E-51 T 12-10-2018 TL08_05875 b1b8208a130f4b0a9d9b26fcf6a2177e 484 Gene3D G3DSA:3.50.50.60 13 379 7.7E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_05875 b1b8208a130f4b0a9d9b26fcf6a2177e 484 Pfam PF01266 FAD dependent oxidoreductase 13 380 8.4E-39 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_05875 b1b8208a130f4b0a9d9b26fcf6a2177e 484 SUPERFAMILY SSF51905 12 406 1.28E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_16425 5329c2921c81e0c38edcf90305e65287 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 1.9E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_15830 2b8d2b7fbdf2f62448d3ac9e36253a8e 391 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 92 318 3.0E-29 T 12-10-2018 IPR018713 Domain of unknown function DUF2236 TL08_25795 89530aefc0989cab3bc69f3303386dc1 153 Gene3D G3DSA:1.20.120.520 1 142 4.2E-22 T 12-10-2018 TL08_25795 89530aefc0989cab3bc69f3303386dc1 153 Pfam PF01814 Hemerythrin HHE cation binding domain 3 125 1.1E-14 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TL08_21490 743dcfb27720a3423ccfee3b2c86a70f 340 SUPERFAMILY SSF51412 3 335 7.78E-54 T 12-10-2018 TL08_21490 743dcfb27720a3423ccfee3b2c86a70f 340 Gene3D G3DSA:3.20.20.70 1 340 2.2E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TL08_21490 743dcfb27720a3423ccfee3b2c86a70f 340 Pfam PF03060 Nitronate monooxygenase 7 334 1.2E-81 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 TL08_11760 f96984eca09122709a25358ae73eeec2 371 Gene3D G3DSA:3.30.565.10 244 368 3.1E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_11760 f96984eca09122709a25358ae73eeec2 371 SMART SM00387 278 369 8.9E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_11760 f96984eca09122709a25358ae73eeec2 371 SUPERFAMILY SSF55874 256 366 1.06E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TL08_11760 f96984eca09122709a25358ae73eeec2 371 Pfam PF07730 Histidine kinase 179 242 3.3E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TL08_11760 f96984eca09122709a25358ae73eeec2 371 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 366 4.1E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_07565 69be350e5d53015922548f338a1ad0fe 131 Pfam PF00293 NUDIX domain 11 109 1.1E-8 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TL08_07565 69be350e5d53015922548f338a1ad0fe 131 SUPERFAMILY SSF55811 7 111 7.58E-19 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TL08_07565 69be350e5d53015922548f338a1ad0fe 131 Gene3D G3DSA:3.90.79.10 4 128 2.1E-19 T 12-10-2018 TL08_13840 b68c6e3bca97f8156f7819ce68eedc38 262 Pfam PF13569 Domain of unknown function (DUF4132) 26 179 9.3E-15 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_09630 b3c244b03292a232fff880ffe3c4de43 223 Pfam PF10821 Protein of unknown function (DUF2567) 74 168 6.7E-8 T 12-10-2018 IPR021213 Protein of unknown function DUF2567 TL08_27035 98db30f98fce6ae5e1ad62a955f38db3 190 Pfam PF02622 Uncharacterized ACR, COG1678 17 173 6.8E-36 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 TL08_27035 98db30f98fce6ae5e1ad62a955f38db3 190 SUPERFAMILY SSF143456 8 184 5.76E-48 T 12-10-2018 TL08_27035 98db30f98fce6ae5e1ad62a955f38db3 190 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 6 187 25.203 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 TL08_27035 98db30f98fce6ae5e1ad62a955f38db3 190 Gene3D G3DSA:3.40.1740.10 2 181 4.7E-60 T 12-10-2018 TL08_17395 f3b410f23b19172521b354bcad440b3a 240 Pfam PF02754 Cysteine-rich domain 3 83 1.8E-14 T 12-10-2018 IPR004017 Cysteine-rich domain TL08_17395 f3b410f23b19172521b354bcad440b3a 240 Pfam PF02754 Cysteine-rich domain 124 208 6.8E-16 T 12-10-2018 IPR004017 Cysteine-rich domain TL08_18990 2572c092d4990e6219f6ebf6b11ab6b3 401 SUPERFAMILY SSF51905 5 290 6.91E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TL08_18990 2572c092d4990e6219f6ebf6b11ab6b3 401 Pfam PF01266 FAD dependent oxidoreductase 5 392 1.7E-60 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TL08_21460 608cb0f6b7c83853dfc710e5a257f44c 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 6 248 7.0E-46 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TL08_21460 608cb0f6b7c83853dfc710e5a257f44c 260 SUPERFAMILY SSF52096 4 250 8.89E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TL08_21460 608cb0f6b7c83853dfc710e5a257f44c 260 Gene3D G3DSA:1.10.12.10 195 250 1.2E-15 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TL08_21460 608cb0f6b7c83853dfc710e5a257f44c 260 Gene3D G3DSA:3.90.226.10 1 192 5.0E-51 T 12-10-2018 TL08_23645 c9cfad78d9c222946e0104bcb45ff864 228 SUPERFAMILY SSF51261 51 220 7.32E-48 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_23645 c9cfad78d9c222946e0104bcb45ff864 228 Pfam PF01551 Peptidase family M23 122 216 4.3E-30 T 12-10-2018 IPR016047 Peptidase M23 TL08_23645 c9cfad78d9c222946e0104bcb45ff864 228 Gene3D G3DSA:2.70.70.10 69 223 2.1E-42 T 12-10-2018 IPR011055 Duplicated hybrid motif TL08_22100 b8b38c3ac460a0a0cef804802d0d3405 191 Gene3D G3DSA:1.10.357.40 39 191 3.2E-40 T 12-10-2018 IPR037238 YbiA-like superfamily TL08_22100 b8b38c3ac460a0a0cef804802d0d3405 191 SUPERFAMILY SSF143990 26 189 2.88E-47 T 12-10-2018 IPR037238 YbiA-like superfamily TL08_22100 b8b38c3ac460a0a0cef804802d0d3405 191 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 29 188 7.3E-46 T 12-10-2018 IPR012816 NADAR TL08_22100 b8b38c3ac460a0a0cef804802d0d3405 191 Pfam PF08719 Domain of unknown function (DUF1768) 43 188 7.2E-51 T 12-10-2018 IPR012816 NADAR TL08_20340 43bf52481f970273e5f4f56c66a4c6e9 206 SUPERFAMILY SSF55961 5 142 9.17E-15 T 12-10-2018 TL08_20340 43bf52481f970273e5f4f56c66a4c6e9 206 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 121 1.1E-7 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 TL08_20340 43bf52481f970273e5f4f56c66a4c6e9 206 Gene3D G3DSA:3.30.530.20 2 149 4.3E-22 T 12-10-2018 IPR023393 START-like domain superfamily TL08_13050 00e6d9682c9dff97d6a29f78f9a83806 301 Pfam PF00722 Glycosyl hydrolases family 16 84 296 6.2E-25 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 TL08_13050 00e6d9682c9dff97d6a29f78f9a83806 301 SUPERFAMILY SSF49899 34 301 1.19E-55 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TL08_13050 00e6d9682c9dff97d6a29f78f9a83806 301 Gene3D G3DSA:2.60.120.200 28 300 6.9E-59 T 12-10-2018 TL08_25835 d1066f97d18f8eeb8954337d1ac4193d 216 Gene3D G3DSA:3.50.30.100 5 202 4.8E-53 T 12-10-2018 TL08_25835 d1066f97d18f8eeb8954337d1ac4193d 216 SUPERFAMILY SSF89562 29 191 2.62E-44 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TL08_25835 d1066f97d18f8eeb8954337d1ac4193d 216 Pfam PF03737 Aldolase/RraA 32 180 1.8E-38 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TL08_20540 7c84e88494051dce4b733b6043d323f5 952 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 785 906 3.1E-31 T 12-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TL08_20540 7c84e88494051dce4b733b6043d323f5 952 Pfam PF13244 Domain of unknown function (DUF4040) 601 666 2.4E-16 T 12-10-2018 IPR025383 Domain of unknown function DUF4040 TL08_20540 7c84e88494051dce4b733b6043d323f5 952 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 9.2E-32 T 12-10-2018 TL08_20540 7c84e88494051dce4b733b6043d323f5 952 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 76 101 9.2E-32 T 12-10-2018 TL08_20540 7c84e88494051dce4b733b6043d323f5 952 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 214 235 9.2E-32 T 12-10-2018 TL08_20540 7c84e88494051dce4b733b6043d323f5 952 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 9.2E-32 T 12-10-2018 TL08_20540 7c84e88494051dce4b733b6043d323f5 952 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 236 262 9.2E-32 T 12-10-2018 TL08_20540 7c84e88494051dce4b733b6043d323f5 952 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 304 316 9.2E-32 T 12-10-2018 TL08_20540 7c84e88494051dce4b733b6043d323f5 952 Pfam PF00361 Proton-conducting membrane transporter 126 405 1.0E-66 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TL08_08735 80110cec3a74fd21f16223ad1fdfccd6 1130 Pfam PF13569 Domain of unknown function (DUF4132) 883 1011 7.5E-25 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_09940 43fb047219cb4ce7cb58cb8a160806c4 274 Gene3D G3DSA:1.20.120.330 144 271 9.5E-35 T 12-10-2018 TL08_09940 43fb047219cb4ce7cb58cb8a160806c4 274 Gene3D G3DSA:3.30.460.10 9 142 5.5E-28 T 12-10-2018 TL08_09940 43fb047219cb4ce7cb58cb8a160806c4 274 SUPERFAMILY SSF81301 12 108 7.63E-5 T 12-10-2018 TL08_02545 ec38a18e79ba53ea65255c2f6155997e 373 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 98 370 7.1E-72 T 12-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 TL08_02545 ec38a18e79ba53ea65255c2f6155997e 373 SUPERFAMILY SSF56322 2 371 7.46E-77 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TL08_02545 ec38a18e79ba53ea65255c2f6155997e 373 Pfam PF00425 chorismate binding enzyme 113 362 5.0E-67 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TL08_02545 ec38a18e79ba53ea65255c2f6155997e 373 Gene3D G3DSA:3.60.120.10 45 372 1.4E-88 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TL08_16760 78f0569d3376a9ba3ecc1e895c47c01c 244 Pfam PF01636 Phosphotransferase enzyme family 58 177 8.1E-9 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TL08_16760 78f0569d3376a9ba3ecc1e895c47c01c 244 SUPERFAMILY SSF56112 9 174 4.24E-18 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TL08_16760 78f0569d3376a9ba3ecc1e895c47c01c 244 Gene3D G3DSA:3.90.1200.10 79 205 1.4E-5 T 12-10-2018 TL08_20480 ad789185520fea7659857ab2ae18f2f8 195 Pfam PF03780 Asp23 family, cell envelope-related function 91 187 5.7E-10 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 TL08_19870 8321b2c36c26cb73a2a1b05b1e2e5251 235 Gene3D G3DSA:1.10.10.60 4 77 3.4E-26 T 12-10-2018 TL08_19870 8321b2c36c26cb73a2a1b05b1e2e5251 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 1.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_19870 8321b2c36c26cb73a2a1b05b1e2e5251 235 SUPERFAMILY SSF46689 20 81 4.24E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_19870 8321b2c36c26cb73a2a1b05b1e2e5251 235 SUPERFAMILY SSF48498 90 228 2.89E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TL08_19870 8321b2c36c26cb73a2a1b05b1e2e5251 235 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 84 228 2.0E-15 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 TL08_19870 8321b2c36c26cb73a2a1b05b1e2e5251 235 Gene3D G3DSA:1.10.357.10 80 229 3.8E-31 T 12-10-2018 TL08_15065 56bb4426ad349d2ff0a9188bfcf20d67 302 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 16 275 4.4E-74 T 12-10-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 TL08_15065 56bb4426ad349d2ff0a9188bfcf20d67 302 Gene3D G3DSA:3.40.50.150 4 294 1.9E-74 T 12-10-2018 TL08_15065 56bb4426ad349d2ff0a9188bfcf20d67 302 Pfam PF04072 Leucine carboxyl methyltransferase 19 198 4.1E-49 T 12-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 TL08_15065 56bb4426ad349d2ff0a9188bfcf20d67 302 SUPERFAMILY SSF53335 15 294 1.41E-65 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_17515 42500d5d4944bd8e4512b2b6317d373f 699 Pfam PF12294 Protein of unknown function (DUF3626) 516 649 5.1E-6 T 12-10-2018 IPR022074 Protein of unknown function DUF3626 TL08_17515 42500d5d4944bd8e4512b2b6317d373f 699 Pfam PF13699 Domain of unknown function (DUF4157) 81 152 4.8E-25 T 12-10-2018 IPR025295 Domain of unknown function DUF4157 TL08_26890 d26cb1c28032e4ceb04e5686bf7b3e3d 266 Gene3D G3DSA:3.40.50.1820 8 233 4.3E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_26890 d26cb1c28032e4ceb04e5686bf7b3e3d 266 SUPERFAMILY SSF53474 12 260 3.46E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_06080 a988faaa7993d8c05f6bc482d6ff39c5 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 69 8.1E-12 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TL08_06080 a988faaa7993d8c05f6bc482d6ff39c5 96 Gene3D G3DSA:3.30.70.100 2 90 1.3E-13 T 12-10-2018 TL08_06080 a988faaa7993d8c05f6bc482d6ff39c5 96 SUPERFAMILY SSF54909 1 70 1.65E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TL08_13565 026bf50f141e5e16f00bbdf206fa78f3 333 Pfam PF01497 Periplasmic binding protein 64 302 7.9E-22 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TL08_13565 026bf50f141e5e16f00bbdf206fa78f3 333 SUPERFAMILY SSF53807 42 304 1.77E-51 T 12-10-2018 TL08_13565 026bf50f141e5e16f00bbdf206fa78f3 333 Gene3D G3DSA:3.40.50.1980 33 176 2.5E-36 T 12-10-2018 TL08_13565 026bf50f141e5e16f00bbdf206fa78f3 333 Gene3D G3DSA:3.40.50.1980 178 332 6.8E-37 T 12-10-2018 TL08_13405 fc5e4cb6a35816cc573a5a4b9f51016b 398 SMART SM00530 11 66 9.8E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_13405 fc5e4cb6a35816cc573a5a4b9f51016b 398 SUPERFAMILY SSF47413 3 68 7.04E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_13405 fc5e4cb6a35816cc573a5a4b9f51016b 398 Gene3D G3DSA:1.10.260.40 5 91 2.0E-11 T 12-10-2018 TL08_27010 2da5ae676e9c7e4d25d5962f816f5153 157 Pfam PF13630 SdpI/YhfL protein family 51 117 2.6E-13 T 12-10-2018 IPR025962 SdpI/YhfL protein family TL08_13350 80d9b1fa7e6b207c6470e180d502d2e5 118 Pfam PF14016 Protein of unknown function (DUF4232) 1 113 1.3E-17 T 12-10-2018 IPR025326 Protein of unknown function DUF4232 TL08_04565 6b5d582e806f767697e2685f0c156f07 199 Pfam PF12079 Protein of unknown function (DUF3558) 16 190 1.5E-20 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 TL08_14815 b642fc048a31a094a583e82157846cb8 659 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 42 556 2.7E-125 T 12-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 TL08_14815 b642fc048a31a094a583e82157846cb8 659 SUPERFAMILY SSF48208 151 379 1.1E-25 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_16250 2285c3db766bfa93ad86b1070663a2d3 1111 SUPERFAMILY SSF48371 696 963 3.6E-6 T 12-10-2018 IPR016024 Armadillo-type fold TL08_06525 843842a3df01b9f771073c8693fe439c 256 SMART SM00849 18 205 1.9E-8 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_06525 843842a3df01b9f771073c8693fe439c 256 Gene3D G3DSA:3.60.15.10 1 255 7.9E-68 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_06525 843842a3df01b9f771073c8693fe439c 256 Pfam PF12706 Beta-lactamase superfamily domain 47 223 5.8E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase TL08_06525 843842a3df01b9f771073c8693fe439c 256 SUPERFAMILY SSF56281 3 254 2.62E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TL08_00865 505210fd4df460b133b8e0324e332cd6 170 SMART SM00347 40 140 1.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00865 505210fd4df460b133b8e0324e332cd6 170 Gene3D G3DSA:1.10.10.10 15 153 3.3E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_00865 505210fd4df460b133b8e0324e332cd6 170 Pfam PF12802 MarR family 53 104 1.6E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00865 505210fd4df460b133b8e0324e332cd6 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 6.3E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00865 505210fd4df460b133b8e0324e332cd6 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 6.3E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00865 505210fd4df460b133b8e0324e332cd6 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 6.3E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_00865 505210fd4df460b133b8e0324e332cd6 170 SUPERFAMILY SSF46785 16 154 1.51E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_23655 d9bcc02cd60cd5c90faaae0ac98e350e 280 Pfam PF13560 Helix-turn-helix domain 5 84 1.5E-15 T 12-10-2018 TL08_23655 d9bcc02cd60cd5c90faaae0ac98e350e 280 SUPERFAMILY SSF47413 28 79 3.02E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_23655 d9bcc02cd60cd5c90faaae0ac98e350e 280 Gene3D G3DSA:3.30.450.180 102 275 5.1E-12 T 12-10-2018 TL08_23655 d9bcc02cd60cd5c90faaae0ac98e350e 280 SMART SM00530 9 81 9.8E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TL08_09550 2239acc0def0f67786b3df735db91ec4 94 Pfam PF02325 YGGT family 10 91 2.0E-13 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 TL08_16695 66ff468598e60207c6c3c6b092862121 509 Pfam PF15892 BNR repeat-containing family member 77 389 9.9E-59 T 12-10-2018 IPR039469 BNR repeat-containing family member TL08_16790 6a78dbb31d3eaaa354a3e41029f8d80f 1163 Pfam PF13569 Domain of unknown function (DUF4132) 873 1077 9.1E-47 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_21700 e698dfb71f8328dc4b0f67ee90b6ad4b 261 SUPERFAMILY SSF56300 2 254 5.02E-31 T 12-10-2018 TL08_21700 e698dfb71f8328dc4b0f67ee90b6ad4b 261 Pfam PF00149 Calcineurin-like phosphoesterase 2 232 5.9E-9 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TL08_21150 0570969d08827580ddd71665b7536f04 211 SMART SM00746 166 204 9.0E-4 T 12-10-2018 IPR011017 TRASH domain TL08_04145 3838240fa67a7b0f418e80f284df0214 358 SUPERFAMILY SSF51695 42 342 1.23E-59 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_04145 3838240fa67a7b0f418e80f284df0214 358 Gene3D G3DSA:3.20.20.190 27 350 2.4E-97 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TL08_04145 3838240fa67a7b0f418e80f284df0214 358 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 47 336 9.7E-39 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TL08_17340 070c7a9f92c2c7cb0e060af1e3652def 197 Pfam PF11611 Domain of unknown function (DUF4352) 67 190 1.1E-27 T 12-10-2018 IPR029051 Domain of unknown function DUF4352 TL08_17340 070c7a9f92c2c7cb0e060af1e3652def 197 Gene3D G3DSA:2.60.40.1240 61 185 1.4E-26 T 12-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily TL08_08545 dab56636d55891a0311165790068854b 444 Pfam PF03993 Domain of Unknown Function (DUF349) 132 205 3.2E-13 T 12-10-2018 IPR007139 Protein of unknown function DUF349 TL08_08545 dab56636d55891a0311165790068854b 444 Pfam PF03993 Domain of Unknown Function (DUF349) 287 359 6.2E-21 T 12-10-2018 IPR007139 Protein of unknown function DUF349 TL08_08545 dab56636d55891a0311165790068854b 444 Pfam PF03993 Domain of Unknown Function (DUF349) 209 281 1.0E-19 T 12-10-2018 IPR007139 Protein of unknown function DUF349 TL08_11110 3123b4e75ee3b16846fb43199ec77284 183 Pfam PF14325 Domain of unknown function (DUF4383) 22 143 5.9E-41 T 12-10-2018 IPR025492 Protein of unknown function DUF4383 TL08_11770 5e8029067a307bf17bb93adf28b214cc 296 Gene3D G3DSA:3.30.470.20 97 265 2.2E-6 T 12-10-2018 TL08_11770 5e8029067a307bf17bb93adf28b214cc 296 SUPERFAMILY SSF56059 90 268 2.21E-10 T 12-10-2018 TL08_11770 5e8029067a307bf17bb93adf28b214cc 296 Gene3D G3DSA:3.30.1490.20 106 165 2.2E-6 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TL08_10300 de51883d1761a77995a848d457b9b95d 329 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 319 2.4E-115 T 12-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 TL08_10300 de51883d1761a77995a848d457b9b95d 329 Pfam PF03741 Integral membrane protein TerC family 69 273 4.3E-50 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TL08_20125 0f39a0b20132ad75fb0e5c3ebf95b641 513 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 12 492 8.3E-54 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 TL08_20125 0f39a0b20132ad75fb0e5c3ebf95b641 513 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 10 472 1.6E-80 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 TL08_01460 773395b0c510ab347b3100c0d4ca4021 273 Pfam PF00482 Type II secretion system (T2SS), protein F 100 223 1.2E-8 T 12-10-2018 IPR018076 Type II secretion system F domain TL08_08755 c195cb5d6a3e87192535ef5ccafbcc75 231 Pfam PF02517 CAAX protease self-immunity 128 216 1.4E-16 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TL08_02725 8354bbdd34f1f6ad6b25bcaf8f878a37 434 Gene3D G3DSA:2.40.420.20 352 431 2.8E-11 T 12-10-2018 TL08_02725 8354bbdd34f1f6ad6b25bcaf8f878a37 434 SUPERFAMILY SSF47090 190 250 2.22E-10 T 12-10-2018 IPR036365 PGBD-like superfamily TL08_02725 8354bbdd34f1f6ad6b25bcaf8f878a37 434 Pfam PF01471 Putative peptidoglycan binding domain 203 249 7.9E-10 T 12-10-2018 IPR002477 Peptidoglycan binding-like TL08_02725 8354bbdd34f1f6ad6b25bcaf8f878a37 434 Gene3D G3DSA:1.10.101.10 191 252 2.8E-8 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 TL08_15740 7e0f62149629f11def94fd87486c195e 123 SUPERFAMILY SSF54427 2 121 7.78E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily TL08_15740 7e0f62149629f11def94fd87486c195e 123 Pfam PF14534 Domain of unknown function (DUF4440) 7 111 3.1E-13 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 TL08_15740 7e0f62149629f11def94fd87486c195e 123 Gene3D G3DSA:3.10.450.50 1 119 4.2E-13 T 12-10-2018 TL08_26370 7549f2a6c6c14bb7ade01cf19f54bf1a 485 Pfam PF08386 TAP-like protein 382 482 7.0E-23 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal TL08_26370 7549f2a6c6c14bb7ade01cf19f54bf1a 485 SUPERFAMILY SSF53474 70 460 1.67E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13920 8455015b4569a3ed00b7e1b64e186407 252 Pfam PF00265 Thymidine kinase 27 191 5.5E-20 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TL08_13920 8455015b4569a3ed00b7e1b64e186407 252 SUPERFAMILY SSF52540 27 163 3.71E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_13920 8455015b4569a3ed00b7e1b64e186407 252 Gene3D G3DSA:3.40.50.300 19 164 3.5E-19 T 12-10-2018 TL08_22195 e3ca6865bf27b800a41a81a010665d2f 262 Pfam PF05552 Conserved TM helix 103 145 4.4E-7 T 12-10-2018 IPR008910 Conserved TM helix TL08_22195 e3ca6865bf27b800a41a81a010665d2f 262 Pfam PF05552 Conserved TM helix 11 55 2.4E-13 T 12-10-2018 IPR008910 Conserved TM helix TL08_19540 c9009b8414e1e8be7bcd4fc6da375de1 324 SUPERFAMILY SSF53756 54 322 5.76E-16 T 12-10-2018 TL08_19540 c9009b8414e1e8be7bcd4fc6da375de1 324 Gene3D G3DSA:3.40.50.2000 182 323 5.0E-12 T 12-10-2018 TL08_19540 c9009b8414e1e8be7bcd4fc6da375de1 324 Pfam PF00534 Glycosyl transferases group 1 213 300 3.9E-7 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TL08_06140 54012cb47b7b120b90f5f546655742ff 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 6.9E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_05545 534a79d9d52614dd71392d70ed933210 450 Pfam PF01757 Acyltransferase family 67 396 2.2E-37 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_08420 e95856b07a5077e8c6026f33430126ea 126 PIRSF PIRSF006910 1 125 1.2E-49 T 12-10-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted TL08_22570 f616181d6409776d551952a927e63eca 132 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 6.6E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22570 f616181d6409776d551952a927e63eca 132 SMART SM00345 18 77 2.8E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TL08_22570 f616181d6409776d551952a927e63eca 132 SUPERFAMILY SSF46785 7 81 1.58E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_22570 f616181d6409776d551952a927e63eca 132 Gene3D G3DSA:1.10.10.10 11 131 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_11720 40291255f43e7c3f0b1b49bef9c6c7d9 226 Pfam PF00578 AhpC/TSA family 88 185 5.0E-13 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TL08_11720 40291255f43e7c3f0b1b49bef9c6c7d9 226 SUPERFAMILY SSF52833 87 219 2.48E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TL08_11720 40291255f43e7c3f0b1b49bef9c6c7d9 226 Gene3D G3DSA:3.40.30.10 86 223 1.8E-23 T 12-10-2018 TL08_11720 40291255f43e7c3f0b1b49bef9c6c7d9 226 ProSitePatterns PS00194 Thioredoxin family active site. 113 131 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TL08_00385 9424355598ca5db25070325fd128028a 113 Pfam PF04341 Protein of unknown function, DUF485 19 106 1.3E-35 T 12-10-2018 IPR007436 Protein of unknown function DUF485 TL08_14530 9ebb4d4a91bcbbb1965144aca432a80d 126 SUPERFAMILY SSF46785 31 125 2.18E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_14530 9ebb4d4a91bcbbb1965144aca432a80d 126 Pfam PF01638 HxlR-like helix-turn-helix 41 125 2.5E-24 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_14530 9ebb4d4a91bcbbb1965144aca432a80d 126 Gene3D G3DSA:1.10.10.10 24 126 3.0E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_12245 553362968dd15aebf3c3ebfc08396a04 365 Pfam PF02361 Cobalt transport protein 20 228 4.1E-7 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TL08_10965 4ab3b178d05b6da6f7c1e7a58caef678 164 SUPERFAMILY SSF50891 6 147 4.17E-7 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TL08_10965 4ab3b178d05b6da6f7c1e7a58caef678 164 Gene3D G3DSA:2.40.100.20 2 163 1.3E-53 T 12-10-2018 TL08_10965 4ab3b178d05b6da6f7c1e7a58caef678 164 Pfam PF12903 Protein of unknown function (DUF3830) 7 161 2.2E-59 T 12-10-2018 IPR024532 Protein of unknown function DUF3830 TL08_09995 cef7aa4c4a5a4734d2a915f1c7009090 125 Pfam PF13453 Transcription factor zinc-finger 4 42 3.1E-17 T 12-10-2018 IPR027392 Transcription factor zinc-finger TL08_05845 661c00e2dc7fd9f4e5ee4abfa09a370d 384 Pfam PF04027 Domain of unknown function (DUF371) 9 129 5.5E-16 T 12-10-2018 IPR007171 Protein of unknown function DUF371 TL08_05845 661c00e2dc7fd9f4e5ee4abfa09a370d 384 Gene3D G3DSA:2.60.120.630 3 133 2.4E-18 T 12-10-2018 IPR023131 Mth639-like domain superfamily TL08_21295 89bc260b4e028f18cf2fb18cc24c612f 316 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 124 314 9.6E-33 T 12-10-2018 IPR015402 Protein of unknown function DUF1980 TL08_14730 448812d4e1da44b4e2ccdd407c6a25ef 317 Pfam PF13803 Domain of unknown function (DUF4184) 29 162 1.5E-25 T 12-10-2018 IPR025238 Protein of unknown function DUF4184 TL08_08590 84d27421c03ae4365d3872bca2f4a1dc 113 Pfam PF03477 ATP cone domain 1 84 6.4E-15 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TL08_08590 84d27421c03ae4365d3872bca2f4a1dc 113 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 103 51.654 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TL08_26960 544101fe7734a3ce03fedc4487b5eefe 129 SUPERFAMILY SSF102546 2 129 6.54E-37 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 TL08_26960 544101fe7734a3ce03fedc4487b5eefe 129 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 129 29.23 T 12-10-2018 IPR023064 D-ribose pyranase GO:0016872 TL08_26960 544101fe7734a3ce03fedc4487b5eefe 129 Pfam PF05025 RbsD / FucU transport protein family 2 127 5.1E-41 T 12-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 TL08_26960 544101fe7734a3ce03fedc4487b5eefe 129 Gene3D G3DSA:3.40.1650.10 8 125 3.0E-31 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 TL08_01970 a884ccba4d0cdeeeeab7a631e542fdad 480 Pfam PF00982 Glycosyltransferase family 20 13 474 3.1E-149 T 12-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 TL08_01970 a884ccba4d0cdeeeeab7a631e542fdad 480 SUPERFAMILY SSF53756 12 475 8.16E-143 T 12-10-2018 TL08_01970 a884ccba4d0cdeeeeab7a631e542fdad 480 Gene3D G3DSA:3.40.50.2000 252 460 7.3E-164 T 12-10-2018 TL08_01970 a884ccba4d0cdeeeeab7a631e542fdad 480 Gene3D G3DSA:3.40.50.2000 36 471 7.3E-164 T 12-10-2018 TL08_23755 39e72599139776463148bbf7ea9bb1b2 213 Pfam PF12079 Protein of unknown function (DUF3558) 30 207 7.9E-27 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 TL08_27015 6d1876476be02a0e03b8ea0d95288b63 207 Pfam PF12079 Protein of unknown function (DUF3558) 17 200 3.1E-18 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 TL08_16050 7ac021ceaff25d6987dcdc795c8e9b3f 183 SUPERFAMILY SSF46689 6 83 7.7E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TL08_16050 7ac021ceaff25d6987dcdc795c8e9b3f 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TL08_16050 7ac021ceaff25d6987dcdc795c8e9b3f 183 Gene3D G3DSA:1.10.357.10 3 178 4.6E-25 T 12-10-2018 TL08_10345 a0ae1eb9f3cb7930dbed9269e11e4be0 203 Gene3D G3DSA:1.20.120.1760 7 202 3.9E-59 T 12-10-2018 TL08_10345 a0ae1eb9f3cb7930dbed9269e11e4be0 203 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 7.1E-10 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TL08_10345 a0ae1eb9f3cb7930dbed9269e11e4be0 203 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TL08_26905 688caa078abb2a2caf52bb9dcf337a70 371 PIRSF PIRSF015921 7 371 3.3E-77 T 12-10-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 TL08_26905 688caa078abb2a2caf52bb9dcf337a70 371 Pfam PF00487 Fatty acid desaturase 87 344 4.5E-40 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 TL08_01000 48b31ea9bd56310bcfa90740c3f7b0a4 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 2.0E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_16915 d22e00b24943208e2375324831b6a94d 126 SUPERFAMILY SSF55298 1 125 1.35E-34 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_16915 d22e00b24943208e2375324831b6a94d 126 Pfam PF01042 Endoribonuclease L-PSP 12 123 1.3E-26 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TL08_16915 d22e00b24943208e2375324831b6a94d 126 Gene3D G3DSA:3.30.1330.40 6 126 9.4E-38 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TL08_08575 55e4720a1dffeed35013c8a389d17bfb 351 SUPERFAMILY SSF101898 26 268 3.4E-10 T 12-10-2018 TL08_05050 69e210682073640c68884e7d97c2cfd3 190 Gene3D G3DSA:3.40.47.10 10 187 1.9E-5 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TL08_01370 3bc463f5e6e15d44f65a608fde06a19a 66 Pfam PF04149 Domain of unknown function (DUF397) 7 58 6.9E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_14165 9f1b4e064e4d61754d77e804319edd4d 387 Gene3D G3DSA:3.60.10.10 1 294 7.7E-27 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_14165 9f1b4e064e4d61754d77e804319edd4d 387 SUPERFAMILY SSF56219 1 288 1.7E-24 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_14165 9f1b4e064e4d61754d77e804319edd4d 387 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 284 2.0E-15 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TL08_08035 d5f379ae0899f4702d11190c429a688e 247 SUPERFAMILY SSF53335 12 215 1.2E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_08035 d5f379ae0899f4702d11190c429a688e 247 Pfam PF13649 Methyltransferase domain 29 123 4.6E-12 T 12-10-2018 TL08_08035 d5f379ae0899f4702d11190c429a688e 247 Gene3D G3DSA:3.40.50.150 11 212 1.1E-28 T 12-10-2018 TL08_24095 ec8f2b756a84ce85daf75df3c974cbc5 340 Pfam PF03756 A-factor biosynthesis hotdog domain 205 329 2.2E-15 T 12-10-2018 IPR005509 A-factor biosynthesis hotdog domain TL08_24095 ec8f2b756a84ce85daf75df3c974cbc5 340 Pfam PF03756 A-factor biosynthesis hotdog domain 30 166 4.8E-23 T 12-10-2018 IPR005509 A-factor biosynthesis hotdog domain TL08_23225 b6c76ea2ab493be0df2d2f944aac587c 278 SUPERFAMILY SSF89392 98 263 2.0E-5 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX TL08_19100 0c3a7973d34ecb0ba510dcb1e1145da8 408 Pfam PF00144 Beta-lactamase 70 392 7.6E-56 T 12-10-2018 IPR001466 Beta-lactamase-related TL08_19100 0c3a7973d34ecb0ba510dcb1e1145da8 408 SUPERFAMILY SSF56601 67 385 1.06E-68 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TL08_19100 0c3a7973d34ecb0ba510dcb1e1145da8 408 Gene3D G3DSA:3.40.710.10 63 396 2.9E-96 T 12-10-2018 TL08_11185 973f2ea62c03f0475aa3ac71f3f55fa3 335 Gene3D G3DSA:3.20.20.100 7 323 5.0E-64 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_11185 973f2ea62c03f0475aa3ac71f3f55fa3 335 Pfam PF00248 Aldo/keto reductase family 19 321 7.7E-40 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_11185 973f2ea62c03f0475aa3ac71f3f55fa3 335 SUPERFAMILY SSF51430 8 322 2.88E-60 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_18150 af16c08380ff0d01d40b696f806ca98d 410 Pfam PF03601 Conserved hypothetical protein 698 62 384 2.3E-49 T 12-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 TL08_18150 af16c08380ff0d01d40b696f806ca98d 410 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 276 379 2.0E-9 T 12-10-2018 TL08_15240 6b961ec9b6b12edcfb394057f18cc518 445 Pfam PF12770 CHAT domain 111 430 1.1E-8 T 12-10-2018 IPR024983 CHAT domain TL08_25680 3b3c86e5fb3bce248dc4b23d6558db4c 274 SUPERFAMILY SSF53448 1 255 3.38E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_25680 3b3c86e5fb3bce248dc4b23d6558db4c 274 Gene3D G3DSA:3.90.550.10 1 256 7.9E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TL08_21540 6679240708a310185742edf5f1d5c935 568 Pfam PF05960 Bacterial protein of unknown function (DUF885) 28 565 7.4E-158 T 12-10-2018 IPR010281 Protein of unknown function DUF885 TL08_07030 7ddc0419cd51e91f689406251362c6e2 236 Pfam PF03713 Domain of unknown function (DUF305) 75 233 2.9E-46 T 12-10-2018 IPR005183 Domain of unknown function DUF305 TL08_07030 7ddc0419cd51e91f689406251362c6e2 236 Gene3D G3DSA:1.20.1260.10 68 236 4.3E-52 T 12-10-2018 IPR012347 Ferritin-like TL08_06575 336eb13666a430b1f32244e7bade1289 178 SUPERFAMILY SSF51182 37 160 3.85E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TL08_06575 336eb13666a430b1f32244e7bade1289 178 Pfam PF05995 Cysteine dioxygenase type I 47 160 3.4E-17 T 12-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 TL08_06575 336eb13666a430b1f32244e7bade1289 178 Gene3D G3DSA:2.60.120.10 8 168 1.4E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TL08_16600 f023fb0438f677a11bd7417bbd5a65f2 275 Pfam PF01925 Sulfite exporter TauE/SafE 18 269 1.5E-26 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TL08_04595 9b71f181920396004f9cf6e0c0cb92d8 535 SUPERFAMILY SSF140459 26 182 2.04E-8 T 12-10-2018 TL08_17155 4ba7c692df70eb79a0b626b41de25fd6 413 Gene3D G3DSA:1.20.1250.20 1 369 7.8E-34 T 12-10-2018 TL08_17155 4ba7c692df70eb79a0b626b41de25fd6 413 Pfam PF05977 Transmembrane secretion effector 6 380 1.5E-30 T 12-10-2018 IPR010290 Transmembrane secretion effector TL08_17155 4ba7c692df70eb79a0b626b41de25fd6 413 SUPERFAMILY SSF103473 1 378 9.94E-38 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_25820 0b35eed64f9dbb820afc7ca65b3c3314 208 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 22 200 1.8E-19 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 TL08_06490 fcecc2ede6763a2ccf1e77c2ce04e9f6 151 SMART SM00232 1 136 1.3E-24 T 12-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 TL08_06490 fcecc2ede6763a2ccf1e77c2ce04e9f6 151 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 120 1.2E-26 T 12-10-2018 IPR028090 JAB domain, prokaryotic TL08_06490 fcecc2ede6763a2ccf1e77c2ce04e9f6 151 Gene3D G3DSA:3.40.140.10 1 143 3.3E-34 T 12-10-2018 TL08_06490 fcecc2ede6763a2ccf1e77c2ce04e9f6 151 SUPERFAMILY SSF102712 2 130 1.06E-27 T 12-10-2018 TL08_16495 35a6fa4f3b2c946c88d2b11b2f76344b 400 Pfam PF07690 Major Facilitator Superfamily 16 338 8.8E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TL08_16495 35a6fa4f3b2c946c88d2b11b2f76344b 400 Gene3D G3DSA:1.20.1250.20 206 384 1.1E-29 T 12-10-2018 TL08_16495 35a6fa4f3b2c946c88d2b11b2f76344b 400 Gene3D G3DSA:1.20.1250.20 9 188 1.6E-15 T 12-10-2018 TL08_16495 35a6fa4f3b2c946c88d2b11b2f76344b 400 SUPERFAMILY SSF103473 10 398 3.01E-45 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_17045 b3a556e888f3c589d91289bb35d558aa 317 SUPERFAMILY SSF161098 91 297 9.48E-17 T 12-10-2018 IPR035906 MetI-like superfamily TL08_17045 b3a556e888f3c589d91289bb35d558aa 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 5.6E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TL08_17045 b3a556e888f3c589d91289bb35d558aa 317 Gene3D G3DSA:1.10.3720.10 85 307 4.0E-24 T 12-10-2018 IPR035906 MetI-like superfamily TL08_08320 87314b3da1292a832d0cf2bf0a63f558 106 Pfam PF11298 Protein of unknown function (DUF3099) 12 80 1.5E-28 T 12-10-2018 IPR021449 Protein of unknown function DUF3099 TL08_04875 c9547ee628f8c5dcf1ff6883b43a20ce 317 Pfam PF04235 Protein of unknown function (DUF418) 156 305 5.8E-31 T 12-10-2018 IPR007349 Domain of unknown function DUF418 TL08_18655 34220e23a7b2bd9b586eb669760c3788 150 Pfam PF01638 HxlR-like helix-turn-helix 19 105 2.9E-23 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TL08_18655 34220e23a7b2bd9b586eb669760c3788 150 Gene3D G3DSA:1.10.10.10 1 150 2.0E-46 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_18655 34220e23a7b2bd9b586eb669760c3788 150 SUPERFAMILY SSF46785 6 144 9.82E-39 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_11170 fce321767fe3d7165ed64dedab812309 647 Gene3D G3DSA:2.60.40.10 59 150 7.0E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold TL08_11170 fce321767fe3d7165ed64dedab812309 647 SUPERFAMILY SSF69318 174 601 3.66E-15 T 12-10-2018 TL08_16955 04b862f7b360a4bcbcc059c34a21036d 468 Pfam PF12802 MarR family 355 416 1.1E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TL08_16955 04b862f7b360a4bcbcc059c34a21036d 468 SUPERFAMILY SSF46785 338 424 4.34E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TL08_16955 04b862f7b360a4bcbcc059c34a21036d 468 Gene3D G3DSA:1.10.10.10 338 453 3.7E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TL08_07365 0f05d83aabd5bc0379e83ce80817df12 144 Pfam PF10739 Protein of unknown function (DUF2550) 11 137 3.4E-43 T 12-10-2018 IPR019675 Protein of unknown function DUF2550 TL08_24515 c4971a9387548f90064ffb7e9ffe3d92 97 Pfam PF11222 Protein of unknown function (DUF3017) 17 90 1.2E-19 T 12-10-2018 IPR021385 Protein of unknown function DUF3017 TL08_11780 c23416cd51700cc64580ff82194d01d5 338 Pfam PF02628 Cytochrome oxidase assembly protein 27 203 5.9E-16 T 12-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 TL08_16965 5243a72d5d3276acd01ddac6f6a92c42 87 Gene3D G3DSA:3.30.1310.10 6 87 4.9E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_16965 5243a72d5d3276acd01ddac6f6a92c42 87 Pfam PF02575 YbaB/EbfC DNA-binding family 23 86 6.7E-7 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_16965 5243a72d5d3276acd01ddac6f6a92c42 87 SUPERFAMILY SSF82607 14 86 1.7E-5 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_15660 366f0ee50b10f5f5c276b92501d0bb71 230 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 6 224 8.0E-28 T 12-10-2018 IPR010843 Uncharacterised protein family AroM TL08_15660 366f0ee50b10f5f5c276b92501d0bb71 230 Pfam PF07302 AroM protein 7 224 1.0E-64 T 12-10-2018 IPR010843 Uncharacterised protein family AroM TL08_26325 d5d38df3cdbe8bf2541059b4649d5dc5 513 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 51 503 4.1E-97 T 12-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 TL08_26325 d5d38df3cdbe8bf2541059b4649d5dc5 513 Pfam PF00939 Sodium:sulfate symporter transmembrane region 33 501 1.1E-88 T 12-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 TL08_00200 3fe81a15a50df57291f8d655c88f9e8d 342 SUPERFAMILY SSF53335 146 333 1.95E-20 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TL08_00200 3fe81a15a50df57291f8d655c88f9e8d 342 Gene3D G3DSA:3.40.50.150 108 338 3.4E-19 T 12-10-2018 TL08_00200 3fe81a15a50df57291f8d655c88f9e8d 342 Pfam PF13489 Methyltransferase domain 162 326 4.0E-7 T 12-10-2018 TL08_21075 8bbc00f13fae8e41f4721884e946d231 642 Gene3D G3DSA:3.40.50.300 250 506 4.6E-22 T 12-10-2018 TL08_21075 8bbc00f13fae8e41f4721884e946d231 642 SUPERFAMILY SSF52540 230 448 1.44E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_19785 aac488ddd02712e9829aeb8952724b17 296 Pfam PF13560 Helix-turn-helix domain 29 89 2.1E-10 T 12-10-2018 TL08_19785 aac488ddd02712e9829aeb8952724b17 296 SUPERFAMILY SSF47413 21 85 3.64E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TL08_19785 aac488ddd02712e9829aeb8952724b17 296 Gene3D G3DSA:1.10.260.40 17 85 4.4E-7 T 12-10-2018 TL08_00875 d8c29631ab59081d4586b0b15ee021e8 913 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 870 903 0.0011 T 12-10-2018 TL08_00875 d8c29631ab59081d4586b0b15ee021e8 913 Gene3D G3DSA:3.60.10.10 504 807 6.2E-35 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_00875 d8c29631ab59081d4586b0b15ee021e8 913 SUPERFAMILY SSF56219 505 807 1.07E-28 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TL08_09740 86183eb01f711e8468e174cdd82c369b 424 Pfam PF01757 Acyltransferase family 63 393 7.5E-14 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_25125 5dd389b8d2152abdca6153c350a5f2d9 469 Gene3D G3DSA:1.20.1740.10 33 466 8.8E-80 T 12-10-2018 TL08_25125 5dd389b8d2152abdca6153c350a5f2d9 469 PIRSF PIRSF006060 21 467 1.9E-73 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TL08_25125 5dd389b8d2152abdca6153c350a5f2d9 469 Pfam PF13520 Amino acid permease 43 425 8.0E-39 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TL08_14545 576ba4cecb4382707f2cb4e2af6ca7f6 158 Pfam PF07510 Protein of unknown function (DUF1524) 59 151 2.8E-7 T 12-10-2018 IPR011089 Domain of unknown function DUF1524 TL08_23125 ce49c5d8e743a61fb6ed0ec905266e58 213 Pfam PF13796 Putative sensor 19 190 6.9E-20 T 12-10-2018 IPR025828 Putative sensor domain TL08_22085 6158da00c78d5d10fd8e92ebc54b3504 245 Pfam PF02591 C4-type zinc ribbon domain 203 237 2.8E-10 T 12-10-2018 IPR003743 C4-type zinc ribbon domain TL08_07635 58ead2bf2f0ebf7a3725d8929cac8234 539 Pfam PF00135 Carboxylesterase family 37 516 1.1E-104 T 12-10-2018 IPR002018 Carboxylesterase, type B TL08_07635 58ead2bf2f0ebf7a3725d8929cac8234 539 Gene3D G3DSA:3.40.50.1820 33 539 1.7E-140 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_07635 58ead2bf2f0ebf7a3725d8929cac8234 539 SUPERFAMILY SSF53474 37 535 7.63E-114 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_18400 7cd1331c8b26925bf587ccb245ebfca7 284 Gene3D G3DSA:3.90.25.10 138 258 1.1E-34 T 12-10-2018 TL08_18400 7cd1331c8b26925bf587ccb245ebfca7 284 Gene3D G3DSA:3.40.50.720 3 267 1.1E-34 T 12-10-2018 TL08_18400 7cd1331c8b26925bf587ccb245ebfca7 284 SUPERFAMILY SSF51735 2 245 2.63E-19 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_04300 82f16419fdfb805267903258a7add160 158 SUPERFAMILY SSF160424 10 142 2.88E-18 T 12-10-2018 IPR036170 Probable antitoxin YezG superfamily TL08_00805 812d35315abc5121619c5be4cc4b6952 58 Pfam PF14013 MT0933-like antitoxin protein 9 54 7.0E-9 T 12-10-2018 IPR028037 Antitoxin Rv0909/MT0933 TL08_26645 83b0a58d77020c5c2832f556f11a8cc6 543 Pfam PF00350 Dynamin family 50 155 3.7E-10 T 12-10-2018 IPR022812 Dynamin superfamily TL08_26645 83b0a58d77020c5c2832f556f11a8cc6 543 SUPERFAMILY SSF52540 42 263 1.09E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TL08_10130 e839aef5a2de009060d3af39543f31e6 117 Pfam PF02467 Transcription factor WhiB 54 99 1.7E-9 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TL08_23600 5384c0b2609bad78ca9792398df3b9ec 178 Pfam PF03703 Bacterial PH domain 78 149 3.2E-18 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_03805 bc9d3e43d1260c106e06706364a3d402 145 Gene3D G3DSA:3.10.180.10 1 145 2.1E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03805 bc9d3e43d1260c106e06706364a3d402 145 SUPERFAMILY SSF54593 5 144 1.03E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_00230 9f1b2bc57767cff1cfda6cd3645dc800 332 Pfam PF05425 Copper resistance protein D 231 329 2.4E-22 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 TL08_22395 54a09f449f6e108f45eee4833cbb99ff 201 Pfam PF02620 Uncharacterized ACR, COG1399 73 182 2.1E-28 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD TL08_22565 b158dc65c441cef962f01c0bb0f9bfc8 189 Pfam PF12028 Protein of unknown function (DUF3515) 22 185 1.1E-45 T 12-10-2018 IPR021903 Protein of unknown function DUF3515 TL08_25470 893efc6b155c6df540a27e13f1eb16e5 157 SUPERFAMILY SSF54593 34 154 1.79E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_25470 893efc6b155c6df540a27e13f1eb16e5 157 Gene3D G3DSA:3.10.180.10 30 155 1.0E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_17565 5575ea77ce898d92fef89f454215dfe4 241 Pfam PF14065 Protein of unknown function (DUF4255) 4 179 1.0E-39 T 12-10-2018 IPR025351 Protein of unknown function DUF4255 TL08_01215 dcf7274da23d07c218f78f255d30b87d 100 Pfam PF02467 Transcription factor WhiB 8 70 1.6E-23 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TL08_01215 dcf7274da23d07c218f78f255d30b87d 100 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 2 75 18.342 T 12-10-2018 IPR003482 Transcription factor WhiB TL08_00290 fc998682842030c38d0ad7cc4bf17e80 320 SUPERFAMILY SSF51430 2 316 1.96E-89 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_00290 fc998682842030c38d0ad7cc4bf17e80 320 Gene3D G3DSA:3.20.20.100 1 318 6.0E-108 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TL08_00290 fc998682842030c38d0ad7cc4bf17e80 320 Pfam PF00248 Aldo/keto reductase family 16 314 2.6E-65 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TL08_21780 3f9b517e80c1b49d0363e1a6fdbd45b7 132 PIRSF PIRSF017385 1 132 7.8E-49 T 12-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TL08_21780 3f9b517e80c1b49d0363e1a6fdbd45b7 132 Pfam PF12270 Cytochrome c oxidase subunit IV 1 129 8.7E-51 T 12-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TL08_00235 691894f39295132470c1a09b4197648f 188 Gene3D G3DSA:2.60.40.1220 30 129 4.1E-24 T 12-10-2018 TL08_00235 691894f39295132470c1a09b4197648f 188 Pfam PF04234 CopC domain 30 123 5.3E-23 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 TL08_00235 691894f39295132470c1a09b4197648f 188 SUPERFAMILY SSF81296 29 124 3.36E-23 T 12-10-2018 IPR014756 Immunoglobulin E-set TL08_21760 9a9719d1e81096300c0672c14f815357 230 SUPERFAMILY SSF81452 34 228 1.57E-56 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21760 9a9719d1e81096300c0672c14f815357 230 Gene3D G3DSA:1.20.120.80 45 230 8.7E-52 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_21760 9a9719d1e81096300c0672c14f815357 230 Pfam PF00510 Cytochrome c oxidase subunit III 48 228 1.7E-26 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_25970 8505113af516288168ccfe77738c1b58 322 Pfam PF06089 L-asparaginase II 6 311 7.2E-114 T 12-10-2018 IPR010349 L-asparaginase II TL08_17295 8befa7cc18f94a7125a39a662d9a753b 176 Pfam PF10027 Predicted integral membrane protein (DUF2269) 22 170 1.1E-6 T 12-10-2018 IPR018729 Protein of unknown function DUF2269, transmembrane TL08_15120 ce74f5da6e2f6c4dae894271ce26fc6b 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 8.0E-19 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_13265 4f17c573cb8d705c5691f1557206f2c6 734 SUPERFAMILY SSF48208 324 724 1.17E-49 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TL08_12680 70398c1829e796efa95e77f5e50fa07c 110 Pfam PF04149 Domain of unknown function (DUF397) 7 42 6.8E-12 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_13135 226a862a2b2f44ef6b63009ac19b0d9f 266 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 14 266 5.1E-114 T 12-10-2018 IPR022292 Conserved hypothetical protein CHP03843 TL08_00530 d7d2101910d4fcbe880cdf16725b993c 274 Pfam PF02517 CAAX protease self-immunity 170 257 7.1E-12 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TL08_17865 50ce84b43d1627e2ea3975996924498f 120 Pfam PF04892 VanZ like family 34 105 2.7E-7 T 12-10-2018 IPR006976 VanZ-like TL08_17230 84948a80689249ca9ab7f4a534311f76 139 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 131 5.6E-14 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TL08_17230 84948a80689249ca9ab7f4a534311f76 139 SUPERFAMILY SSF54593 1 139 1.48E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_17230 84948a80689249ca9ab7f4a534311f76 139 Gene3D G3DSA:3.10.180.10 2 138 2.0E-45 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_26695 c819fdf9c87aecaac37019e2c7ed64e2 556 Pfam PF00474 Sodium:solute symporter family 43 410 2.4E-18 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TL08_26695 c819fdf9c87aecaac37019e2c7ed64e2 556 Gene3D G3DSA:1.20.1730.10 30 519 4.3E-31 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily TL08_10910 19eb98912cbe8cab1248cf757d5bc9b8 241 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 1 232 9.0E-20 T 12-10-2018 TL08_00725 5b895f4210dfc4d159dd0eaf68700e5a 195 Pfam PF10759 Protein of unknown function (DUF2587) 48 182 4.6E-77 T 12-10-2018 IPR019695 Bacterial proteasome activator GO:0061136 TL08_25030 099cb58f79e000edc8a61b409ab7a21d 225 Pfam PF14016 Protein of unknown function (DUF4232) 90 217 1.0E-25 T 12-10-2018 IPR025326 Protein of unknown function DUF4232 TL08_01900 cf7f8062a9222e45a273ac3d5db6f616 451 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 163 298 1.2E-17 T 12-10-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain TL08_23315 f9d6d12f938b02dcfec7338741eb6a95 913 SUPERFAMILY SSF53474 586 663 1.86E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_20710 5e8f3f2c09a727273dfb196a29b1b42f 670 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 17 363 1.2E-107 T 12-10-2018 IPR016624 Uncharacterised conserved protein UCP014753 TL08_15965 2892d9a72c8b3f36fb359e32cd2aa5d0 180 SUPERFAMILY SSF103473 36 131 4.05E-5 T 12-10-2018 IPR036259 MFS transporter superfamily TL08_09355 e8524f4a5d3fbc021cc783005dbf58b6 165 Gene3D G3DSA:1.20.90.10 36 148 1.9E-40 T 12-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 TL08_09355 e8524f4a5d3fbc021cc783005dbf58b6 165 SUPERFAMILY SSF48619 37 147 3.91E-35 T 12-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 TL08_09355 e8524f4a5d3fbc021cc783005dbf58b6 165 Pfam PF09056 Prokaryotic phospholipase A2 42 147 1.7E-40 T 12-10-2018 IPR015141 Phospholipase A2, prokaryotic/fungal TL08_18265 fe3a81478f693d18716f1d19076589f2 201 Pfam PF02575 YbaB/EbfC DNA-binding family 34 113 3.6E-9 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TL08_18265 fe3a81478f693d18716f1d19076589f2 201 SUPERFAMILY SSF82607 27 114 1.31E-6 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TL08_11350 07301a2b4ddec29feadee014ecafd0e5 141 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 2.9E-21 T 12-10-2018 IPR009293 Uncharacterised protein family UPF0478 TL08_18245 93c097f8d402e50ec808886af3256f6a 396 Pfam PF04231 Endonuclease I 181 389 3.3E-42 T 12-10-2018 IPR007346 Endonuclease I GO:0004518 TL08_18245 93c097f8d402e50ec808886af3256f6a 396 SUPERFAMILY SSF54060 178 389 5.18E-57 T 12-10-2018 TL08_20525 0b16ea8021fbdae69d37195215548de6 131 Pfam PF01899 Na+/H+ ion antiporter subunit 5 108 6.1E-26 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TL08_22090 5c79b8796defd9c577e90fd540e16c33 285 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 219 3.6E-47 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TL08_22090 5c79b8796defd9c577e90fd540e16c33 285 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 257 5.0E-65 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TL08_22090 5c79b8796defd9c577e90fd540e16c33 285 SUPERFAMILY SSF102705 4 276 3.92E-75 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily TL08_22090 5c79b8796defd9c577e90fd540e16c33 285 Gene3D G3DSA:3.40.1390.30 102 238 2.2E-63 T 12-10-2018 TL08_22090 5c79b8796defd9c577e90fd540e16c33 285 Gene3D G3DSA:3.40.1390.30 8 250 2.2E-63 T 12-10-2018 TL08_10680 0da17e429763c956fd7df4bce330fb01 263 PIRSF PIRSF006648 2 262 6.4E-65 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_10680 0da17e429763c956fd7df4bce330fb01 263 Pfam PF01061 ABC-2 type transporter 21 225 1.2E-27 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_06035 1262780e1252cb79fef1e2741e065d77 65 Gene3D G3DSA:3.40.50.720 1 59 2.9E-5 T 12-10-2018 TL08_17065 b6e5684484ce2eed712d8d14f1e23512 295 Gene3D G3DSA:1.10.10.60 185 288 6.6E-17 T 12-10-2018 TL08_17065 b6e5684484ce2eed712d8d14f1e23512 295 Pfam PF12833 Helix-turn-helix domain 209 285 5.2E-14 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_17065 b6e5684484ce2eed712d8d14f1e23512 295 SMART SM00342 202 285 2.0E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TL08_13635 d29afd512af16bfd98e6e940ede35be3 253 Pfam PF10067 Predicted membrane protein (DUF2306) 76 234 2.1E-35 T 12-10-2018 IPR018750 Protein of unknown function DUF2306, membrane TL08_25985 89e5fb58c47145f93e936ae41721e728 480 SUPERFAMILY SSF140459 24 178 1.73E-7 T 12-10-2018 TL08_09020 d6d447a198f7617edadc07031547d6b9 393 Pfam PF04892 VanZ like family 48 188 3.8E-18 T 12-10-2018 IPR006976 VanZ-like TL08_01740 8470d9867269ba6c4cfaf24b23d52c0c 289 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 254 275 1.8E-6 T 12-10-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 TL08_02310 aa37686ac4eec9fc76e5c704344b6948 307 Pfam PF01261 Xylose isomerase-like TIM barrel 43 156 1.2E-10 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TL08_02310 aa37686ac4eec9fc76e5c704344b6948 307 Gene3D G3DSA:3.20.20.150 24 299 7.2E-43 T 12-10-2018 TL08_02310 aa37686ac4eec9fc76e5c704344b6948 307 SUPERFAMILY SSF51658 28 297 4.64E-42 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TL08_14365 06c689181d18276c5b836c7ce533fe64 895 Pfam PF08665 PglZ domain 485 649 8.4E-9 T 12-10-2018 IPR013973 PglZ domain TL08_12300 4454ead44415f36b6f04af521455a796 197 Pfam PF13298 DNA polymerase Ligase (LigD) 36 147 3.8E-38 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain TL08_12300 4454ead44415f36b6f04af521455a796 197 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 7 165 3.4E-55 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain TL08_07820 9df2a2d349fcd5a794b6fab560cac8a2 677 Pfam PF05425 Copper resistance protein D 249 345 1.1E-15 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 TL08_07820 9df2a2d349fcd5a794b6fab560cac8a2 677 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 398 643 5.9E-88 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related TL08_09115 8f584100dd23d1221b725fde1adb9a65 281 Pfam PF03883 Peroxide stress protein YaaA 20 233 6.5E-34 T 12-10-2018 IPR005583 Peroxide stress protein YaaA TL08_23615 e953f06c9e2bbd5c975d6343bdf19b03 118 Pfam PF01934 Protein of unknown function DUF86 21 106 3.6E-19 T 12-10-2018 IPR008201 Protein of unknown function DUF86 TL08_00635 82d1236742ef3adf6bae3745dbedd790 156 Pfam PF03994 Domain of Unknown Function (DUF350) 31 84 1.2E-14 T 12-10-2018 IPR007140 Protein of unknown function DUF350 TL08_00635 82d1236742ef3adf6bae3745dbedd790 156 Pfam PF03994 Domain of Unknown Function (DUF350) 101 155 2.3E-10 T 12-10-2018 IPR007140 Protein of unknown function DUF350 TL08_26930 4d3432ab7e6da2e5c34169e2a506f789 402 Pfam PF01594 AI-2E family transporter 17 342 2.5E-62 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like TL08_14855 75b8b4f8c3c3f12f88f3b52a90262e3d 774 Pfam PF04738 Lantibiotic dehydratase, C terminus 74 546 1.6E-19 T 12-10-2018 IPR006827 Lantibiotic dehydratase, N-terminal TL08_14855 75b8b4f8c3c3f12f88f3b52a90262e3d 774 Pfam PF04738 Lantibiotic dehydratase, C terminus 640 718 1.5E-10 T 12-10-2018 IPR006827 Lantibiotic dehydratase, N-terminal TL08_08750 0b88d421d38e4348fe8a730ba744dab0 462 Pfam PF02517 CAAX protease self-immunity 364 452 4.5E-12 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TL08_15655 adda6a9f98223051fee8116cb430f5b3 552 Pfam PF03169 OPT oligopeptide transporter protein 26 186 5.1E-7 T 12-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TL08_15655 adda6a9f98223051fee8116cb430f5b3 552 Pfam PF03169 OPT oligopeptide transporter protein 188 545 6.5E-13 T 12-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TL08_00620 570e566bf169f3d9f3bf5edc64aaff27 444 Pfam PF13845 Septum formation 161 342 1.2E-48 T 12-10-2018 IPR026004 Septum formation-related domain TL08_00620 570e566bf169f3d9f3bf5edc64aaff27 444 Pfam PF13845 Septum formation 78 117 6.1E-7 T 12-10-2018 IPR026004 Septum formation-related domain TL08_02485 a4029862ce902e2e37d4f70d7bc20404 112 Pfam PF14012 Protein of unknown function (DUF4229) 29 89 1.6E-11 T 12-10-2018 IPR025323 Protein of unknown function DUF4229 TL08_01130 2cef20d78689d3123377f16bfe9095f3 413 Pfam PF09594 Glycosyltransferase family 87 127 335 5.8E-5 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 TL08_14970 2f1cfef53202adfae9c2b3a7320a189d 508 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 18 437 3.5E-132 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TL08_03970 2f1d1b52014f1e6faddcb853634e5315 64 Pfam PF04149 Domain of unknown function (DUF397) 7 59 1.7E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_17025 3c32bee58c5359669077f343ac1c0b6f 558 Pfam PF03929 PepSY-associated TM region 85 450 6.1E-66 T 12-10-2018 IPR005625 PepSY-associated TM protein TL08_00335 f4dad3b9907415352d54a904eccec406 444 Pfam PF01757 Acyltransferase family 22 337 6.0E-17 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 TL08_06130 7c3e9ea6db373c6126e621e80e8995a9 81 Pfam PF04149 Domain of unknown function (DUF397) 17 68 3.6E-13 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_21000 2eada98a8f2a4fa69e67ae3edf43e392 295 SUPERFAMILY SSF48239 37 272 1.26E-8 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TL08_22815 614465dc11e351972c236b8b0da34257 226 Pfam PF14103 Domain of unknown function (DUF4276) 11 205 2.4E-9 T 12-10-2018 IPR025455 Protein of unknown function DUF4276 TL08_03780 820c75c084d53f2b6a052b35826c2fa3 173 Pfam PF04417 Protein of unknown function (DUF501) 35 156 1.1E-36 T 12-10-2018 IPR007511 Protein of unknown function DUF501 TL08_10270 cea8d9950e5525cbb7ba856738af2431 131 Gene3D G3DSA:2.40.380.10 1 124 9.7E-27 T 12-10-2018 IPR035930 FomD-like superfamily TL08_10270 cea8d9950e5525cbb7ba856738af2431 131 SUPERFAMILY SSF159234 13 129 3.27E-19 T 12-10-2018 IPR035930 FomD-like superfamily TL08_17505 1a59a5da49879f1b7e2208b879fc17ff 146 Pfam PF06841 T4-like virus tail tube protein gp19 11 143 3.8E-27 T 12-10-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 TL08_17505 1a59a5da49879f1b7e2208b879fc17ff 146 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 6 145 1.4E-26 T 12-10-2018 IPR011747 Conserved hypothetical protein CHP02241 TL08_24010 6cb173fe6edc55c601f462160a447452 179 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 35 156 6.2E-29 T 12-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TL08_09405 1c62b7d082009cf48f5ad10754262ea2 395 Pfam PF00860 Permease family 3 358 5.5E-73 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TL08_23980 5c27fad6d151bcd8d30be5c0420e6029 515 Pfam PF03703 Bacterial PH domain 422 499 6.3E-7 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_23980 5c27fad6d151bcd8d30be5c0420e6029 515 Pfam PF03703 Bacterial PH domain 86 164 9.2E-10 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_23980 5c27fad6d151bcd8d30be5c0420e6029 515 Pfam PF03703 Bacterial PH domain 262 321 3.7E-5 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_23980 5c27fad6d151bcd8d30be5c0420e6029 515 PIRSF PIRSF026631 28 186 2.8E-21 T 12-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 TL08_23980 5c27fad6d151bcd8d30be5c0420e6029 515 PIRSF PIRSF026631 198 504 6.3E-38 T 12-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 TL08_16995 130f00280ac13372d4fdcc888f23d924 64 SUPERFAMILY SSF141000 5 55 6.8E-5 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 TL08_12755 084932c93dd2d10d4cabe15620e98630 343 SUPERFAMILY SSF51679 1 341 7.98E-76 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_12755 084932c93dd2d10d4cabe15620e98630 343 Gene3D G3DSA:3.20.20.30 1 342 2.9E-84 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 TL08_12755 084932c93dd2d10d4cabe15620e98630 343 Pfam PF00296 Luciferase-like monooxygenase 1 305 4.5E-66 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 TL08_20550 7d6c9cf1ffdc44336a5276d7ca629f68 322 Gene3D G3DSA:3.90.920.30 6 282 2.3E-86 T 12-10-2018 TL08_26495 5f1e28edcce176a064c37cbaecc6c25a 48 Pfam PF04149 Domain of unknown function (DUF397) 6 43 2.6E-7 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_01835 93552188c69b3f07a8bf2253a9412318 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 4.7E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_16795 49e9817aa4973ace7c9f574d1082be62 391 Pfam PF13569 Domain of unknown function (DUF4132) 135 316 4.2E-44 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_21850 554f792cff14f1c6f417670c1067581e 421 Gene3D G3DSA:1.20.1740.10 9 421 1.5E-16 T 12-10-2018 TL08_03735 089e06a7a43e56936b21059adad396bd 320 SUPERFAMILY SSF109998 34 154 1.06E-5 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily TL08_17840 af9d7626c152dded4a0403194e1eaa45 307 Pfam PF09851 Short C-terminal domain 278 304 1.0E-8 T 12-10-2018 IPR018649 SHOCT domain TL08_17840 af9d7626c152dded4a0403194e1eaa45 307 Pfam PF14472 Domain of unknown function (DUF4429) 22 114 2.4E-5 T 12-10-2018 IPR027860 Domain of unknown function DUF4429 TL08_17840 af9d7626c152dded4a0403194e1eaa45 307 Pfam PF14472 Domain of unknown function (DUF4429) 149 225 2.8E-13 T 12-10-2018 IPR027860 Domain of unknown function DUF4429 TL08_15700 a286d868f9aee3ad4b961ad7e92513f2 330 Pfam PF00756 Putative esterase 70 326 4.7E-50 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TL08_15700 a286d868f9aee3ad4b961ad7e92513f2 330 SUPERFAMILY SSF53474 55 309 2.01E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15700 a286d868f9aee3ad4b961ad7e92513f2 330 Gene3D G3DSA:3.40.50.1820 17 329 7.5E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15555 eccf21a9c789938fdc508f13184aa40d 95 Gene3D G3DSA:3.40.50.1820 2 95 4.7E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_15555 eccf21a9c789938fdc508f13184aa40d 95 SUPERFAMILY SSF53474 3 94 2.93E-14 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TL08_13645 8166034dd1a4bd70f2616bc85004f7fb 288 Pfam PF00583 Acetyltransferase (GNAT) family 188 275 3.2E-7 T 12-10-2018 IPR000182 GNAT domain TL08_13645 8166034dd1a4bd70f2616bc85004f7fb 288 SUPERFAMILY SSF55729 81 283 1.89E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TL08_13645 8166034dd1a4bd70f2616bc85004f7fb 288 Gene3D G3DSA:3.40.630.30 8 287 8.4E-24 T 12-10-2018 TL08_17510 0250739cc87e63fa6c60c86a081a2925 504 Pfam PF17482 Phage tail sheath C-terminal domain 387 492 3.7E-21 T 12-10-2018 IPR020287 Tail sheath protein, C-terminal domain TL08_17510 0250739cc87e63fa6c60c86a081a2925 504 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 225 386 2.5E-33 T 12-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain TL08_17510 0250739cc87e63fa6c60c86a081a2925 504 Gene3D G3DSA:3.40.50.11780 219 343 1.5E-10 T 12-10-2018 TL08_22970 bb0354ad628add5a7cd3f30c48cf5cfa 111 Pfam PF02656 Domain of unknown function (DUF202) 13 76 1.0E-11 T 12-10-2018 IPR003807 Domain of unknown function DUF202 TL08_11020 454589075b9e7af2910691ef477cbdbb 209 Gene3D G3DSA:3.40.50.300 13 196 1.9E-14 T 12-10-2018 TL08_26790 878f443c5ab391ae3662ee466ecf3dc9 173 Pfam PF06803 Protein of unknown function (DUF1232) 93 127 1.2E-13 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 TL08_20150 6b46d225ec2332be326161beb1106ed2 300 SUPERFAMILY SSF55486 88 292 4.05E-9 T 12-10-2018 TL08_24365 6895908cf284b1fc715de263d69a8e6d 247 Pfam PF01061 ABC-2 type transporter 9 208 2.3E-7 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_24365 6895908cf284b1fc715de263d69a8e6d 247 PIRSF PIRSF006648 2 243 3.5E-22 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TL08_26505 32aac1f373fe6c03404ae305175eb830 66 Pfam PF04149 Domain of unknown function (DUF397) 10 61 3.6E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_20585 7c36e8ceb9dc4a7d25d6c984e86a1ada 181 Pfam PF11452 Protein of unknown function (DUF3000) 5 175 4.8E-69 T 12-10-2018 IPR021555 Protein of unknown function DUF3000 TL08_24540 1555f2d292285d313cb51eb811ecff6f 1353 Pfam PF14021 Tuberculosis necrotizing toxin 1259 1344 7.5E-29 T 12-10-2018 IPR025331 Tuberculosis necrotizing toxin KEGG: 00760+3.2.2.5 TL08_24540 1555f2d292285d313cb51eb811ecff6f 1353 SUPERFAMILY SSF160424 15 140 9.29E-13 T 12-10-2018 IPR036170 Probable antitoxin YezG superfamily TL08_12110 87148a709b5b48326d91d8b6cbae51e2 71 Pfam PF16827 zinc-finger 4 59 2.0E-6 T 12-10-2018 IPR031795 Putative zinc-finger containing protein TL08_12110 87148a709b5b48326d91d8b6cbae51e2 71 Gene3D G3DSA:2.30.30.990 1 52 7.0E-6 T 12-10-2018 TL08_23975 32f4656913721eca1d85f8943580a41f 169 Pfam PF03703 Bacterial PH domain 76 153 2.5E-17 T 12-10-2018 IPR005182 Domain of unknown function DUF304 TL08_00040 2763102141119dadfea672d0020d7ddd 321 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 205 319 2.0E-44 T 12-10-2018 IPR021949 Domain of unknown function DUF3566. transmembrane TL08_06275 6355e1d21a2b3cd80499a93bcfbe331b 166 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 160 1.5E-60 T 12-10-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger TL08_04585 32543d0346f3b77cbdaba1e2950c10d4 75 Pfam PF04149 Domain of unknown function (DUF397) 7 66 3.0E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_03110 6b5d4940c94e838d59d1a24ba8f8d5ec 169 Pfam PF08044 Domain of unknown function (DUF1707) 22 74 3.4E-20 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_11595 a721a049b935125d08597c29f78a78d2 156 Pfam PF10756 Bacterial PH domain 76 146 2.4E-20 T 12-10-2018 IPR019692 Protein of unknown function DUF2581 TL08_12095 f311c0a634ab5d677690896f4ef4273b 329 Pfam PF13280 WYL domain 146 312 2.7E-34 T 12-10-2018 IPR026881 WYL domain TL08_12095 f311c0a634ab5d677690896f4ef4273b 329 PIRSF PIRSF016838 1 321 1.3E-117 T 12-10-2018 IPR028349 Protein PafC TL08_12735 bca40ff93483050b162346e01eeba77e 341 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 327 8.4E-26 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_25605 e5018dff4fcc55cfe6649eb49af952ed 291 SUPERFAMILY SSF81606 13 289 4.05E-6 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TL08_05125 a60902166b4f9ab5e9692664f9c269b5 251 Pfam PF09335 SNARE associated Golgi protein 47 174 1.1E-22 T 12-10-2018 IPR032816 SNARE associated Golgi protein TL08_08240 4af8669da895e6f291a94b13300fa2e8 269 SUPERFAMILY SSF52266 11 238 4.12E-9 T 12-10-2018 TL08_02810 7914d8c86588779b35c4c632b7c34c9a 305 Pfam PF13460 NAD(P)H-binding 27 186 1.7E-7 T 12-10-2018 IPR016040 NAD(P)-binding domain TL08_02810 7914d8c86588779b35c4c632b7c34c9a 305 Gene3D G3DSA:3.90.25.10 138 271 4.0E-52 T 12-10-2018 TL08_02810 7914d8c86588779b35c4c632b7c34c9a 305 Gene3D G3DSA:3.40.50.720 24 269 4.0E-52 T 12-10-2018 TL08_02810 7914d8c86588779b35c4c632b7c34c9a 305 SUPERFAMILY SSF51735 22 252 2.18E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TL08_07880 8f1a7e1d525581b5090d65fec11081aa 211 Pfam PF12079 Protein of unknown function (DUF3558) 17 206 3.9E-25 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 TL08_00430 01e57e20a2e8a38f545aada2d4e802d0 321 SUPERFAMILY SSF103642 21 40 1.8E-5 T 12-10-2018 TL08_03660 68a257844bb2291decebe52d71dd4429 185 Pfam PF14280 Domain of unknown function (DUF4365) 26 177 4.3E-12 T 12-10-2018 IPR025375 Domain of unknown function DUF4365 TL08_18980 57dfc6dde75716989024dff6831362fd 147 Pfam PF11070 Protein of unknown function (DUF2871) 1 128 2.3E-41 T 12-10-2018 IPR021299 Protein of unknown function DUF2871 TL08_17260 3618460543aec3405fec27b6a67d006b 237 Pfam PF11139 Sap, sulfolipid-1-addressing protein 9 229 1.4E-35 T 12-10-2018 IPR021315 Glycolipid exporter Gap/Sap TL08_20535 84c2626107fbc7815ea9740626b02e9b 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 3 91 2.0E-20 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TL08_10385 bc2e4f479c7b78d5c89ccec1dfb2a5c8 286 Pfam PF03591 AzlC protein 21 155 5.8E-32 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease TL08_16420 b6997c1587bafdf82b7cb022bd3fab47 354 Pfam PF12051 Protein of unknown function (DUF3533) 200 292 4.7E-7 T 12-10-2018 IPR022703 Domain of unknown function DUF3533 TL08_15710 ccdd034d326665fc3323b3a1b7eb9eb0 63 Pfam PF13783 Domain of unknown function (DUF4177) 5 61 1.4E-8 T 12-10-2018 IPR025234 Protein of unknown function DUF4177 TL08_13690 ddd5e22f5614b1a8d7a3d50c4f99f433 215 Pfam PF08044 Domain of unknown function (DUF1707) 8 60 3.6E-17 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 TL08_23365 f5263323bd1ccf64c28d10a8cd3fb5ba 125 Pfam PF12005 Protein of unknown function (DUF3499) 8 105 5.5E-46 T 12-10-2018 IPR021888 Protein of unknown function DUF3499 TL08_20615 0a05090b6c138ae57b5ab19e69a4f56c 82 Pfam PF13396 Phospholipase_D-nuclease N-terminal 18 58 4.6E-6 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal TL08_25045 5d8894aef1d28bc397fb836dbe619595 261 Pfam PF13560 Helix-turn-helix domain 1 54 3.8E-6 T 12-10-2018 TL08_25785 abd4aaa5870ec977914aa70a91c3e2f7 598 SUPERFAMILY SSF53756 64 353 2.83E-8 T 12-10-2018 TL08_26975 073d080db77ee56e6c68da487a61d13a 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 317 2.2E-47 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_25370 612d3eabde5d0f0e61b0f09d41c6aedf 74 Pfam PF04024 PspC domain 15 73 2.8E-17 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal TL08_15170 57c52a4832e6035360de402ea0654858 369 Pfam PF02653 Branched-chain amino acid transport system / permease component 83 341 3.5E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_19520 44a4e4acfa9096bd526210735a107a3c 83 Pfam PF04149 Domain of unknown function (DUF397) 25 78 2.6E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_22020 5561912d6ab9b3253b3f27282e4aa28f 431 Gene3D G3DSA:3.30.2010.10 199 287 1.0E-5 T 12-10-2018 TL08_22020 5561912d6ab9b3253b3f27282e4aa28f 431 Pfam PF01435 Peptidase family M48 215 419 2.9E-18 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TL08_10550 70e47aa3bf563ea0a2056d64ea71da07 563 Pfam PF07907 YibE/F-like protein 156 394 1.2E-70 T 12-10-2018 IPR012507 YibE/F-like TL08_25765 18f46e79fa51fd05fb7863e2be20795c 139 SUPERFAMILY SSF54593 25 132 4.95E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_25765 18f46e79fa51fd05fb7863e2be20795c 139 Gene3D G3DSA:3.10.180.10 10 133 9.1E-13 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TL08_03990 ac68a0b1b1936eda9f634a4a8c41e53f 264 Pfam PF14428 SCP1.201-like deaminase 140 256 3.0E-16 T 12-10-2018 IPR032724 Deaminase, SCP1.201-like TL08_03300 848fec2481ab35a0f371ef0bccb1c4d3 63 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 11 56 3.8E-9 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TL08_03300 848fec2481ab35a0f371ef0bccb1c4d3 63 Pfam PF12728 Helix-turn-helix domain 11 58 8.9E-7 T 12-10-2018 TL08_25205 de9a637dc153eca2781c790acaa0e598 65 Pfam PF10745 Protein of unknown function (DUF2530) 1 65 1.9E-18 T 12-10-2018 IPR019681 Protein of unknown function DUF2530 TL08_23000 0a937cd30f9f3534c63dbcaa436f98fb 293 Pfam PF12679 ABC-2 family transporter protein 71 291 2.6E-7 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TL08_08415 05b38f90076286ff09ba688c520142e6 230 Pfam PF12502 Protein of unknown function (DUF3710) 29 195 3.3E-57 T 12-10-2018 IPR022183 Protein of unknown function DUF3710 TL08_24255 0d55bbba54bd95bf95b039bdf7798e6d 146 Pfam PF00872 Transposase, Mutator family 34 98 4.5E-9 T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TL08_05490 bc65ed89e489d9b24c50795e92265bed 240 Pfam PF01061 ABC-2 type transporter 4 161 5.7E-9 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TL08_25980 7f19d7e76488d8635accd64228efd6b6 61 Pfam PF11273 Protein of unknown function (DUF3073) 2 60 2.1E-23 T 12-10-2018 IPR021426 Protein of unknown function DUF3073 TL08_15790 e29bd2aa4a9e3ad37e5c3d7905b1e4a4 417 Gene3D G3DSA:3.40.109.10 32 165 1.5E-12 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_15790 e29bd2aa4a9e3ad37e5c3d7905b1e4a4 417 Gene3D G3DSA:3.40.109.10 229 410 1.5E-6 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TL08_25990 dc1c55dd985ccc5db30b87df7ac12958 274 Pfam PF14011 EspG family 27 264 5.9E-49 T 12-10-2018 IPR025734 EspG family TL08_14315 efb9fd076c27651e959c2d015c13ffe8 120 Pfam PF02467 Transcription factor WhiB 52 97 2.1E-9 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain TL08_13155 1d005b2fa69348f34ec0b9c127c35d3b 127 Pfam PF11236 Protein of unknown function (DUF3037) 9 126 3.5E-39 T 12-10-2018 IPR021398 Protein of unknown function DUF3037 TL08_04305 a60b81c204aacc339ba241b25c114d82 2209 SUPERFAMILY SSF140453 26 95 9.29E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily TL08_20610 70910ab52761d687a9b1b1bedc74f90d 237 Pfam PF02517 CAAX protease self-immunity 143 227 3.2E-18 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TL08_12090 b15cae55c896596bf7e9dd1d0d17f7cf 316 Pfam PF13280 WYL domain 137 309 1.7E-28 T 12-10-2018 IPR026881 WYL domain TL08_01040 79c3145ec263d2a65246abd43198b2c5 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 328 2.4E-48 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_07875 e43e43758312113d65422691348756c7 465 SUPERFAMILY SSF140459 36 172 1.44E-5 T 12-10-2018 TL08_20465 6e45ace746410cc6427937b5952c2207 198 Pfam PF03780 Asp23 family, cell envelope-related function 74 183 1.4E-33 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 TL08_22105 aa6d2581c8dac5ac5c9a27dc9b139039 304 Pfam PF02104 SURF1 family 28 231 2.0E-28 T 12-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TL08_16185 4a03df858f4cd7fe6b4f03d96a1bdd23 515 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 19 437 1.3E-146 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TL08_18270 1062c0fc785100de949cd80b1e4d9afc 108 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 7 98 1.1E-10 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 TL08_17435 77ba334a7f25413b31a6383aff17faee 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 317 1.1E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_17635 29bfb2a09c06aab49782f1f35302f5c4 273 Pfam PF13349 Putative adhesin 114 271 1.5E-15 T 12-10-2018 IPR025164 Putative adhesin TL08_21650 b649d588674ff98182c239c4d7ff64e0 318 Pfam PF13020 Domain of unknown function (DUF3883) 201 275 1.1E-8 T 12-10-2018 IPR024975 Domain of unknown function DUF3883 TL08_10200 b6fd023a7b8077ad42ac9be4ffa760e6 381 Pfam PF02653 Branched-chain amino acid transport system / permease component 64 334 2.1E-47 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TL08_11070 686488478665c84dc6a517f81d6f8179 147 Pfam PF13581 Histidine kinase-like ATPase domain 26 89 1.8E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TL08_22780 b6d7cc6ad08957e3a3f65aab555ed257 340 Pfam PF07681 DoxX 185 270 2.6E-19 T 12-10-2018 IPR032808 DoxX family TL08_22235 de7c07fc4481da084ca702891974a59d 167 Pfam PF11343 Protein of unknown function (DUF3145) 10 165 4.4E-70 T 12-10-2018 IPR021491 Protein of unknown function DUF3145 TL08_17550 52c668c3e75fc4cb8ee6875113199f5e 202 Pfam PF01810 LysE type translocator 15 202 2.3E-44 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 TL08_19005 e4d4a5bb05e76b77d8560361db68de6c 287 Pfam PF13569 Domain of unknown function (DUF4132) 27 207 4.4E-27 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 TL08_12230 6bfe54a3ee413bf08c693eb6802c5b54 243 Pfam PF05331 Protein of unknown function (DUF742) 133 243 1.1E-28 T 12-10-2018 IPR007995 Protein of unknown function DUF742 TL08_06045 990e579d83fbd583cae5717c883bacce 368 Gene3D G3DSA:1.25.40.290 122 240 1.3E-29 T 12-10-2018 TL08_06045 990e579d83fbd583cae5717c883bacce 368 SUPERFAMILY SSF48371 44 241 6.24E-28 T 12-10-2018 IPR016024 Armadillo-type fold TL08_16875 93a27b10dddec5f90c090fca7150cb62 66 Pfam PF04149 Domain of unknown function (DUF397) 8 59 1.6E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_00090 a02dca30d99403e196e052fde0dc30c1 90 Pfam PF06781 Cell division protein CrgA 1 90 3.9E-36 T 12-10-2018 IPR009619 Cell division protein CrgA TL08_00090 a02dca30d99403e196e052fde0dc30c1 90 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 90 25.392 T 12-10-2018 IPR009619 Cell division protein CrgA TL08_10350 f9874e8321327491c789d3f55a6fabbc 341 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 3 297 4.2E-68 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 TL08_04095 d527667193e579c941fa64c56a6cae82 299 Pfam PF07751 Abi-like protein 30 216 1.4E-44 T 12-10-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like TL08_22720 8304cb5287e2c398af17414d42daa8c4 89 Pfam PF04149 Domain of unknown function (DUF397) 30 81 5.9E-12 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_18650 c29b167fc0150bc9eb08dc9cd57762b7 216 Pfam PF05988 Bacterial protein of unknown function (DUF899) 2 213 2.3E-77 T 12-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like TL08_01410 00158914bb42ea1bcf5e178164a5a8e7 206 Pfam PF12079 Protein of unknown function (DUF3558) 18 200 1.4E-19 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 TL08_04050 94452b31eed9a5e63ffbf7fcc4221bd0 158 Pfam PF14155 Domain of unknown function (DUF4307) 24 134 3.4E-30 T 12-10-2018 IPR025443 Protein of unknown function DUF4307 TL08_13430 509363b1e6e85468d3c05db6676dcf94 269 Pfam PF01040 UbiA prenyltransferase family 16 241 1.6E-18 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TL08_15685 fc773d45a7ae7e2d6ea6ec6317504b66 954 Pfam PF01435 Peptidase family M48 136 346 1.3E-9 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TL08_11090 2e844ae5876abb084e9e9ba1b8d6bccb 88 Pfam PF04972 BON domain 15 76 4.1E-8 T 12-10-2018 IPR007055 BON domain TL08_05720 f455c886ff899f9837b7b18d6f713b92 152 Gene3D G3DSA:3.90.470.20 14 140 1.4E-12 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TL08_01470 40b85c871ae0415f337e9c0f0ebcb7ab 115 Pfam PF14029 Protein of unknown function (DUF4244) 60 111 3.3E-22 T 12-10-2018 IPR025338 Protein of unknown function DUF4244 TL08_05780 82c792e91351d0ff0017a24264ae0dbe 60 Pfam PF04149 Domain of unknown function (DUF397) 4 55 2.3E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 TL08_04295 57b2745cfe83f64cb3369b0e44772b3b 434 SUPERFAMILY SSF160424 13 146 1.96E-15 T 12-10-2018 IPR036170 Probable antitoxin YezG superfamily