UA74_29360 6f9c7452c28d8d9da2c774650225d0af 542 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 535 2.9E-90 T 12-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 UA74_29360 6f9c7452c28d8d9da2c774650225d0af 542 Pfam PF00999 Sodium/hydrogen exchanger family 5 408 2.2E-52 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 UA74_09305 8b352eac904fd673bf82d6a830f6d67a 405 Gene3D G3DSA:1.10.260.40 131 198 6.1E-7 T 12-10-2018 UA74_09305 8b352eac904fd673bf82d6a830f6d67a 405 SMART SM00530 138 195 3.9E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_09305 8b352eac904fd673bf82d6a830f6d67a 405 Pfam PF13560 Helix-turn-helix domain 135 192 3.3E-6 T 12-10-2018 UA74_09305 8b352eac904fd673bf82d6a830f6d67a 405 SUPERFAMILY SSF47413 134 201 5.63E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_07015 1909027e647a9ab3c0a673ca09ca9434 215 Pfam PF01300 Telomere recombination 23 197 8.1E-48 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 UA74_07015 1909027e647a9ab3c0a673ca09ca9434 215 Gene3D G3DSA:3.90.870.10 3 212 9.6E-68 T 12-10-2018 UA74_07015 1909027e647a9ab3c0a673ca09ca9434 215 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 11 207 2.2E-62 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 UA74_07015 1909027e647a9ab3c0a673ca09ca9434 215 SUPERFAMILY SSF55821 5 206 4.58E-57 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily UA74_13875 c107a7a64631b2b3697e8bf0631ce177 422 SUPERFAMILY SSF51604 172 415 2.62E-60 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_13875 c107a7a64631b2b3697e8bf0631ce177 422 Gene3D G3DSA:3.20.20.120 165 399 4.0E-97 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_13875 c107a7a64631b2b3697e8bf0631ce177 422 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 76 173 6.8E-15 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_13875 c107a7a64631b2b3697e8bf0631ce177 422 SMART SM00922 191 287 3.2E-20 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_13875 c107a7a64631b2b3697e8bf0631ce177 422 Gene3D G3DSA:3.30.390.10 47 164 4.0E-97 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_13875 c107a7a64631b2b3697e8bf0631ce177 422 SUPERFAMILY SSF54826 44 173 1.11E-23 T 12-10-2018 UA74_13875 c107a7a64631b2b3697e8bf0631ce177 422 Pfam PF13378 Enolase C-terminal domain-like 198 408 6.9E-52 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_01495 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 SMART SM00347 47 146 7.3E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_01495 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 Gene3D G3DSA:1.10.10.10 4 162 2.6E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_01495 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 Pfam PF12802 MarR family 58 110 4.6E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_01495 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_01495 4a3ea4bf2454bd8b1877d5eef4cc74e0 180 SUPERFAMILY SSF46785 27 161 1.67E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04145 2f56d768c7c19013b8efe0c1c8b9663e 220 Gene3D G3DSA:1.10.10.10 123 206 1.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04145 2f56d768c7c19013b8efe0c1c8b9663e 220 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 41 203 5.5E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_04145 2f56d768c7c19013b8efe0c1c8b9663e 220 SUPERFAMILY SSF88946 36 120 1.53E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_04145 2f56d768c7c19013b8efe0c1c8b9663e 220 Pfam PF08281 Sigma-70, region 4 149 199 1.9E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_04145 2f56d768c7c19013b8efe0c1c8b9663e 220 SUPERFAMILY SSF88659 142 204 2.99E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_04145 2f56d768c7c19013b8efe0c1c8b9663e 220 Gene3D G3DSA:1.10.1740.10 31 111 9.0E-18 T 12-10-2018 UA74_04145 2f56d768c7c19013b8efe0c1c8b9663e 220 Pfam PF04542 Sigma-70 region 2 46 114 3.7E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_26835 101d01b7f045f6d430e66307325adade 134 Pfam PF02575 YbaB/EbfC DNA-binding family 18 98 1.4E-7 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_26835 101d01b7f045f6d430e66307325adade 134 Gene3D G3DSA:3.30.1310.10 9 106 1.8E-5 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_01800 2aecff50162198bac96edd054e5f78f3 842 Gene3D G3DSA:1.50.10.10 475 842 2.8E-80 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_01800 2aecff50162198bac96edd054e5f78f3 842 Gene3D G3DSA:3.40.50.1000 25 236 1.7E-48 T 12-10-2018 IPR023214 HAD superfamily UA74_01800 2aecff50162198bac96edd054e5f78f3 842 SUPERFAMILY SSF48208 461 837 6.05E-92 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_01800 2aecff50162198bac96edd054e5f78f3 842 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 23 250 1.9E-34 T 12-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 UA74_01800 2aecff50162198bac96edd054e5f78f3 842 Gene3D G3DSA:3.30.70.1020 104 180 1.7E-48 T 12-10-2018 UA74_01800 2aecff50162198bac96edd054e5f78f3 842 SUPERFAMILY SSF56784 24 250 3.67E-35 T 12-10-2018 IPR036412 HAD-like superfamily UA74_01800 2aecff50162198bac96edd054e5f78f3 842 Pfam PF02358 Trehalose-phosphatase 27 217 4.6E-32 T 12-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 UA74_01800 2aecff50162198bac96edd054e5f78f3 842 Pfam PF00723 Glycosyl hydrolases family 15 474 784 1.0E-35 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 UA74_21815 596a2f855cc8be95a3ea9e1df647ccb9 553 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 284 302 2.4E-5 T 12-10-2018 UA74_21815 596a2f855cc8be95a3ea9e1df647ccb9 553 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 371 394 2.4E-5 T 12-10-2018 UA74_21815 596a2f855cc8be95a3ea9e1df647ccb9 553 Pfam PF00939 Sodium:sulfate symporter transmembrane region 88 536 1.5E-24 T 12-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 UA74_10455 596f3968270cb04153252d770de190ec 338 Gene3D G3DSA:3.40.50.620 10 338 8.0E-109 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_10455 596f3968270cb04153252d770de190ec 338 Pfam PF00579 tRNA synthetases class I (W and Y) 10 292 1.4E-56 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_10455 596f3968270cb04153252d770de190ec 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 19 35 1.1E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_10455 596f3968270cb04153252d770de190ec 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 218 1.1E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_10455 596f3968270cb04153252d770de190ec 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 1.1E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_10455 596f3968270cb04153252d770de190ec 338 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 153 174 1.1E-20 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_10455 596f3968270cb04153252d770de190ec 338 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_10455 596f3968270cb04153252d770de190ec 338 SUPERFAMILY SSF52374 10 338 5.63E-78 T 12-10-2018 UA74_10455 596f3968270cb04153252d770de190ec 338 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 6 338 1.3E-86 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UA74_10455 596f3968270cb04153252d770de190ec 338 Gene3D G3DSA:1.10.240.10 203 306 8.0E-109 T 12-10-2018 UA74_07050 544c3623e23aaa6df8cc6902f2ad9703 275 PRINTS PR00125 ATP synthase delta subunit signature 233 248 2.3E-7 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07050 544c3623e23aaa6df8cc6902f2ad9703 275 PRINTS PR00125 ATP synthase delta subunit signature 248 266 2.3E-7 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07050 544c3623e23aaa6df8cc6902f2ad9703 275 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 109 273 3.1E-20 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07050 544c3623e23aaa6df8cc6902f2ad9703 275 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 235 254 - T 12-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07050 544c3623e23aaa6df8cc6902f2ad9703 275 Pfam PF00213 ATP synthase delta (OSCP) subunit 110 273 4.2E-31 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07050 544c3623e23aaa6df8cc6902f2ad9703 275 Hamap MF_01416 ATP synthase subunit delta [atpD]. 47 275 13.953 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_17720 732bb7bb2ddd2419b477c57b6718ec53 936 SMART SM00487 282 519 0.0017 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_17720 732bb7bb2ddd2419b477c57b6718ec53 936 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 42 226 7.7E-21 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain UA74_17720 732bb7bb2ddd2419b477c57b6718ec53 936 Pfam PF00271 Helicase conserved C-terminal domain 568 679 4.2E-5 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_17720 732bb7bb2ddd2419b477c57b6718ec53 936 Gene3D G3DSA:3.40.50.300 554 696 1.8E-7 T 12-10-2018 UA74_17720 732bb7bb2ddd2419b477c57b6718ec53 936 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 306 680 4.9E-51 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core UA74_17720 732bb7bb2ddd2419b477c57b6718ec53 936 Gene3D G3DSA:3.40.50.300 285 500 2.7E-12 T 12-10-2018 UA74_17720 732bb7bb2ddd2419b477c57b6718ec53 936 Pfam PF00270 DEAD/DEAH box helicase 299 489 1.2E-5 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_17720 732bb7bb2ddd2419b477c57b6718ec53 936 SUPERFAMILY SSF52540 299 680 2.98E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_17720 732bb7bb2ddd2419b477c57b6718ec53 936 Gene3D G3DSA:1.10.3210.30 24 266 6.4E-64 T 12-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily UA74_13985 02d85d4ba5592e58980218e3fd774824 308 Pfam PF02016 LD-carboxypeptidase 16 293 1.4E-65 T 12-10-2018 IPR003507 Peptidase family S66 UA74_13985 02d85d4ba5592e58980218e3fd774824 308 SUPERFAMILY SSF141986 171 299 2.48E-35 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UA74_13985 02d85d4ba5592e58980218e3fd774824 308 SUPERFAMILY SSF52317 4 168 8.7E-40 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_13985 02d85d4ba5592e58980218e3fd774824 308 Gene3D G3DSA:3.40.50.10740 4 159 6.9E-48 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal UA74_13985 02d85d4ba5592e58980218e3fd774824 308 PIRSF PIRSF028757 5 307 1.7E-62 T 12-10-2018 IPR003507 Peptidase family S66 UA74_13985 02d85d4ba5592e58980218e3fd774824 308 Gene3D G3DSA:3.50.30.60 175 300 7.2E-36 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UA74_25695 52508209586783d71c2059fbb2ae4d31 734 Gene3D G3DSA:2.40.50.140 43 139 7.7E-22 T 12-10-2018 UA74_25695 52508209586783d71c2059fbb2ae4d31 734 Pfam PF00270 DEAD/DEAH box helicase 292 446 4.6E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_25695 52508209586783d71c2059fbb2ae4d31 734 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 24 698 1.9E-201 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 UA74_25695 52508209586783d71c2059fbb2ae4d31 734 Gene3D G3DSA:3.40.50.300 472 663 2.1E-52 T 12-10-2018 UA74_25695 52508209586783d71c2059fbb2ae4d31 734 SUPERFAMILY SSF50249 12 181 1.03E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_25695 52508209586783d71c2059fbb2ae4d31 734 SUPERFAMILY SSF52540 400 632 1.5E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25695 52508209586783d71c2059fbb2ae4d31 734 Gene3D G3DSA:3.40.50.300 212 460 1.2E-80 T 12-10-2018 UA74_25695 52508209586783d71c2059fbb2ae4d31 734 SUPERFAMILY SSF52540 187 463 2.38E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25695 52508209586783d71c2059fbb2ae4d31 734 SMART SM00487 266 470 8.4E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_25695 52508209586783d71c2059fbb2ae4d31 734 Pfam PF00271 Helicase conserved C-terminal domain 550 621 2.7E-18 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_25695 52508209586783d71c2059fbb2ae4d31 734 Pfam PF17191 RecG wedge domain 13 177 9.9E-11 T 12-10-2018 IPR033454 RecG, wedge domain UA74_25695 52508209586783d71c2059fbb2ae4d31 734 SMART SM00490 537 622 5.1E-22 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_22195 910c039c254d7b788a78231178240282 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 48 1.7E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22195 910c039c254d7b788a78231178240282 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 3.9E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22195 910c039c254d7b788a78231178240282 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 3.9E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22195 910c039c254d7b788a78231178240282 216 SUPERFAMILY SSF46689 2 70 1.64E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_22195 910c039c254d7b788a78231178240282 216 Gene3D G3DSA:1.10.357.10 1 210 5.4E-59 T 12-10-2018 UA74_22195 910c039c254d7b788a78231178240282 216 SUPERFAMILY SSF48498 78 144 6.68E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_06785 085848547c5a763020c7d28bddf56b4d 392 SUPERFAMILY SSF53474 8 391 3.12E-97 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06785 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 196 209 4.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_06785 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 109 127 4.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_06785 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 366 388 4.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_06785 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 182 195 4.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_06785 085848547c5a763020c7d28bddf56b4d 392 PRINTS PR00412 Epoxide hydrolase signature 137 152 4.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_06785 085848547c5a763020c7d28bddf56b4d 392 PIRSF PIRSF001112 2 392 2.4E-105 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 UA74_06785 085848547c5a763020c7d28bddf56b4d 392 Gene3D G3DSA:3.40.50.1820 3 392 3.0E-129 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06785 085848547c5a763020c7d28bddf56b4d 392 Pfam PF06441 Epoxide hydrolase N terminus 15 117 1.2E-31 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 UA74_04820 af791b1906246bf90fbf951fdfc6a2d5 319 Gene3D G3DSA:3.90.79.20 69 180 1.8E-10 T 12-10-2018 UA74_04820 af791b1906246bf90fbf951fdfc6a2d5 319 Gene3D G3DSA:3.90.79.10 182 319 1.8E-34 T 12-10-2018 UA74_04820 af791b1906246bf90fbf951fdfc6a2d5 319 ProSitePatterns PS00893 Nudix box signature. 215 236 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_04820 af791b1906246bf90fbf951fdfc6a2d5 319 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 74 146 5.8E-7 T 12-10-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 UA74_04820 af791b1906246bf90fbf951fdfc6a2d5 319 SUPERFAMILY SSF55811 133 312 1.34E-45 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_04820 af791b1906246bf90fbf951fdfc6a2d5 319 Pfam PF00293 NUDIX domain 183 291 7.3E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_04820 af791b1906246bf90fbf951fdfc6a2d5 319 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 150 179 5.9E-10 T 12-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 UA74_11760 da44fb7b08631e8411625173c3a7548d 199 SUPERFAMILY SSF81301 17 151 7.93E-28 T 12-10-2018 UA74_11760 da44fb7b08631e8411625173c3a7548d 199 Pfam PF14907 Uncharacterised nucleotidyltransferase 17 182 5.9E-9 T 12-10-2018 IPR039498 Uncharacterised nucleotidyltransferase UA74_11760 da44fb7b08631e8411625173c3a7548d 199 Gene3D G3DSA:3.30.460.40 13 151 4.1E-12 T 12-10-2018 UA74_06605 e7e175fc1ea69578a0fe21ed9d5f3ecc 197 Gene3D G3DSA:3.40.50.1950 8 197 3.3E-19 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 UA74_06605 e7e175fc1ea69578a0fe21ed9d5f3ecc 197 Pfam PF02441 Flavoprotein 18 163 2.1E-14 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UA74_06605 e7e175fc1ea69578a0fe21ed9d5f3ecc 197 SUPERFAMILY SSF52507 22 193 4.71E-20 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 UA74_29310 21870aaa3144dd63c46a2f92daee9fc0 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 4.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_29310 21870aaa3144dd63c46a2f92daee9fc0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_29310 21870aaa3144dd63c46a2f92daee9fc0 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_29310 21870aaa3144dd63c46a2f92daee9fc0 200 Gene3D G3DSA:1.10.357.10 4 197 4.8E-39 T 12-10-2018 UA74_29310 21870aaa3144dd63c46a2f92daee9fc0 200 SUPERFAMILY SSF46689 7 78 2.57E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 Gene3D G3DSA:3.30.379.10 27 158 1.6E-24 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 SUPERFAMILY SSF49785 527 630 2.55E-18 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 Gene3D G3DSA:3.20.20.80 165 506 9.5E-74 T 12-10-2018 UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 SUPERFAMILY SSF55545 41 162 7.33E-14 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 Pfam PF00754 F5/8 type C domain 526 628 8.4E-15 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 123 143 1.1E-12 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 288 306 1.1E-12 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 187 208 1.1E-12 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 PRINTS PR00738 Glycosyl hydrolase family 20 signature 310 323 1.1E-12 T 12-10-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 SUPERFAMILY SSF51445 167 488 3.76E-69 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 Gene3D G3DSA:2.60.120.260 512 646 4.9E-20 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 168 430 3.0E-49 T 12-10-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 UA74_19850 a4c6bc1280744fe5fde853a1b6920fc9 648 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 41 161 2.4E-17 T 12-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal UA74_05545 33c4b27d0e11b592309b9955e9432655 387 Pfam PF13378 Enolase C-terminal domain-like 171 372 6.6E-64 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_05545 33c4b27d0e11b592309b9955e9432655 387 SMART SM00922 166 262 2.3E-25 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_05545 33c4b27d0e11b592309b9955e9432655 387 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 47 145 3.8E-14 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_05545 33c4b27d0e11b592309b9955e9432655 387 SUPERFAMILY SSF51604 133 374 1.03E-74 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_05545 33c4b27d0e11b592309b9955e9432655 387 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 212 243 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_05545 33c4b27d0e11b592309b9955e9432655 387 SUPERFAMILY SSF54826 16 146 6.23E-29 T 12-10-2018 UA74_05545 33c4b27d0e11b592309b9955e9432655 387 Gene3D G3DSA:3.30.390.10 17 373 2.3E-156 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_05545 33c4b27d0e11b592309b9955e9432655 387 Gene3D G3DSA:3.20.20.120 138 370 2.3E-156 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_01935 f2b5300df71416d62021ff5f588cf058 277 Gene3D G3DSA:3.20.20.30 127 273 1.8E-12 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_01935 f2b5300df71416d62021ff5f588cf058 277 Pfam PF00296 Luciferase-like monooxygenase 18 115 1.6E-5 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_01935 f2b5300df71416d62021ff5f588cf058 277 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 5 275 7.3E-107 T 12-10-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted UA74_01935 f2b5300df71416d62021ff5f588cf058 277 Gene3D G3DSA:3.20.20.30 12 119 2.4E-6 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_01935 f2b5300df71416d62021ff5f588cf058 277 SUPERFAMILY SSF51679 15 274 2.52E-27 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_04450 311ebee46d4932b6682b91125157b58b 209 Pfam PF03358 NADPH-dependent FMN reductase 7 134 7.1E-18 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_04450 311ebee46d4932b6682b91125157b58b 209 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 7 199 2.1E-47 T 12-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 UA74_04450 311ebee46d4932b6682b91125157b58b 209 Gene3D G3DSA:3.40.50.360 2 209 1.8E-63 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_04450 311ebee46d4932b6682b91125157b58b 209 SUPERFAMILY SSF52218 8 200 5.5E-49 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 1033 1075 3.2E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 328 361 2.9E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1048 1081 3.3E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 395 428 6.3E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 56 89 1.1E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1082 1115 1.5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 775 808 12.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 90 123 0.0052 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 980 1013 0.001 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 809 842 0.005 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 294 327 0.0039 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 192 225 370.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 22 55 0.49 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 260 293 34.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 497 530 1.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1150 1183 46.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 877 910 21.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 531 564 10.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 843 876 2.6E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 673 706 2.3E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 707 740 0.0045 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 158 191 4.7E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 741 774 0.0053 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 429 462 2.0E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 226 259 3.2E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1116 1149 35.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 946 979 1.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 463 496 0.009 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 639 672 2.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 571 604 0.0026 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 124 157 23.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 605 638 0.057 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SMART SM00028 1014 1047 0.084 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SUPERFAMILY SSF48452 977 1180 7.49E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 808 928 1.4E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 373 478 3.2E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 220 301 2.0E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SUPERFAMILY SSF48452 650 909 8.35E-37 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SUPERFAMILY SSF48452 401 739 2.28E-43 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 1076 1264 2.9E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 SUPERFAMILY SSF48452 9 360 3.49E-51 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 584 636 7.6E-4 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 8 55 0.017 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 814 877 5.7E-7 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 514 558 0.01 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 748 806 0.016 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 137 190 0.0049 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 69 122 9.5E-6 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 401 460 9.3E-6 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 961 1013 0.0025 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 307 361 3.8E-7 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 644 707 7.9E-10 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF13432 Tetratricopeptide repeat 1054 1115 6.0E-4 T 12-10-2018 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 143 219 5.2E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 565 631 2.2E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 302 372 8.2E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 3 69 5.1E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 632 807 1.1E-38 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 479 564 1.9E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 947 1032 7.9E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Gene3D G3DSA:1.25.40.10 70 142 4.8E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11135 fb5299cf55737e8db79e6189cc1fba69 1264 Pfam PF00515 Tetratricopeptide repeat 228 257 1.1E-6 T 12-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 608 623 1.3E-44 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 627 649 1.3E-44 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 469 487 1.3E-44 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 495 519 1.3E-44 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 523 542 1.3E-44 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 553 573 1.3E-44 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 Gene3D G3DSA:2.130.10.120 75 430 4.9E-209 T 12-10-2018 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 SUPERFAMILY SSF53474 439 696 2.95E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 530 560 - T 12-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 Pfam PF00326 Prolyl oligopeptidase family 489 700 9.5E-53 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 9 411 6.0E-66 T 12-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 Gene3D G3DSA:3.40.50.1820 17 695 4.9E-209 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07920 24ab639c1120194ee8ac3f548814d1ef 706 SUPERFAMILY SSF50993 6 423 1.26E-68 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00668 Condensation domain 1843 2287 2.8E-100 T 12-10-2018 IPR001242 Condensation domain UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.47.10 3 453 3.8E-188 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2341 2778 4.8E-117 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF52151 545 833 1.41E-63 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.50.720 1181 1725 1.5E-110 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.30.559.10 1845 2214 1.3E-124 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.30.300.30 2748 2853 9.9E-33 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.366.10 547 849 3.7E-138 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.30.70.3290 458 892 3.7E-138 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00823 Phosphopantetheine attachment site 2863 2932 0.0023 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00823 Phosphopantetheine attachment site 1748 1819 3.3E-9 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF47336 2855 2928 3.4E-15 T 12-10-2018 IPR036736 ACP-like superfamily UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1458 1652 1.3E-46 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00825 Beta-ketoacyl synthase 13 440 8.2E-209 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00826 907 1066 8.8E-45 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF51735 1195 1443 1.1E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:1.10.1200.10 2854 2931 5.6E-18 T 12-10-2018 IPR036736 ACP-like superfamily UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2462 2473 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:1.10.1200.10 1747 1818 1.6E-10 T 12-10-2018 IPR036736 ACP-like superfamily UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF53474 2942 3159 3.59E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 270 387 2.6E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.50.12780 2299 2746 2.5E-116 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF51735 1454 1712 1.74E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00698 Acyl transferase domain 547 864 3.1E-71 T 12-10-2018 IPR014043 Acyl transferase UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00501 AMP-binding enzyme 2310 2754 7.9E-87 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF14765 Polyketide synthase dehydratase 907 1188 6.3E-71 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF13193 AMP-binding enzyme C-terminal domain 2762 2837 1.7E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.10.129.110 906 1180 2.9E-71 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1774 1789 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 262 6.5E-81 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF52777 1846 2021 5.0E-40 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.30.559.30 2025 2267 1.3E-124 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF53901 9 436 1.09E-96 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF08659 KR domain 1458 1650 1.0E-56 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00975 Thioesterase domain 2952 3045 1.6E-19 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF55048 672 736 5.49E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00550 Phosphopantetheine attachment site 1752 1807 1.7E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF00550 Phosphopantetheine attachment site 2867 2927 4.0E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 391 504 9.9E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF47336 1747 1819 7.2E-11 T 12-10-2018 IPR036736 ACP-like superfamily UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:3.40.50.1820 2946 3158 8.4E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00824 Thioesterase 2954 3148 8.3E-5 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF56801 2270 2876 6.8E-145 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 549 846 3.2E-104 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 175 191 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 Gene3D G3DSA:1.20.890.40 3044 3096 8.4E-59 T 12-10-2018 UA74_18000 d108006b43f32b0d2ed68cbae0b6d174 3167 SUPERFAMILY SSF52777 2027 2274 5.11E-56 T 12-10-2018 UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 SUPERFAMILY SSF46785 32 98 1.78E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 Gene3D G3DSA:3.40.640.10 146 367 2.2E-76 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 Gene3D G3DSA:3.90.1150.10 127 469 2.2E-76 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 SUPERFAMILY SSF53383 111 469 6.33E-71 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 Gene3D G3DSA:1.10.10.10 26 95 2.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 Pfam PF00155 Aminotransferase class I and II 150 468 3.7E-22 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 94 1.1E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 1.4E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 1.4E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_28745 0dfb73f30f74b3f82619412e32ceb738 491 SMART SM00345 35 94 5.6E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_20365 594091299517a38cb41d41f8f3ad4d94 320 Gene3D G3DSA:1.10.150.240 22 127 1.6E-51 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_20365 594091299517a38cb41d41f8f3ad4d94 320 Gene3D G3DSA:3.40.50.1000 11 230 1.6E-51 T 12-10-2018 IPR023214 HAD superfamily UA74_20365 594091299517a38cb41d41f8f3ad4d94 320 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 219 1.9E-13 T 12-10-2018 UA74_20365 594091299517a38cb41d41f8f3ad4d94 320 SUPERFAMILY SSF56784 9 252 5.51E-39 T 12-10-2018 IPR036412 HAD-like superfamily UA74_20365 594091299517a38cb41d41f8f3ad4d94 320 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 119 225 8.4E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 SUPERFAMILY SSF56425 236 354 2.09E-40 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 PIRSF PIRSF000171 1 567 1.5E-45 T 12-10-2018 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 593 1.6E-282 T 12-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 SUPERFAMILY SSF51905 2 436 7.78E-75 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 SUPERFAMILY SSF46977 445 593 1.57E-42 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 Pfam PF00890 FAD binding domain 7 400 6.7E-115 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 593 2.3E-40 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 593 4.4E-248 T 12-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 Gene3D G3DSA:3.50.50.60 7 411 1.8E-159 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 6.3E-5 T 12-10-2018 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 6.3E-5 T 12-10-2018 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 Gene3D G3DSA:3.90.700.10 246 349 1.8E-159 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 12-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27505 eeb27cc1bae19bd72b1b58b1e52e2350 593 Gene3D G3DSA:1.20.58.100 426 541 1.5E-33 T 12-10-2018 UA74_23195 d146d3532fc3b4b7005e70e2f5ee4cb5 213 SUPERFAMILY SSF117987 3 86 2.04E-16 T 12-10-2018 UA74_23195 d146d3532fc3b4b7005e70e2f5ee4cb5 213 SUPERFAMILY SSF117987 94 208 3.4E-22 T 12-10-2018 UA74_23195 d146d3532fc3b4b7005e70e2f5ee4cb5 213 Gene3D G3DSA:3.30.70.1200 1 89 7.3E-19 T 12-10-2018 UA74_23195 d146d3532fc3b4b7005e70e2f5ee4cb5 213 Gene3D G3DSA:3.30.70.1210 93 209 8.7E-21 T 12-10-2018 UA74_23195 d146d3532fc3b4b7005e70e2f5ee4cb5 213 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 26 208 1.1E-18 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 UA74_23195 d146d3532fc3b4b7005e70e2f5ee4cb5 213 SMART SM01101 3 208 5.0E-45 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 UA74_23195 d146d3532fc3b4b7005e70e2f5ee4cb5 213 Pfam PF08798 CRISPR associated protein 4 208 5.0E-45 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 UA74_17825 0bda24234e65ba0c90649a65a0ff4341 298 SUPERFAMILY SSF56112 47 278 2.33E-29 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_17825 0bda24234e65ba0c90649a65a0ff4341 298 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 40 275 3.0E-21 T 12-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 UA74_17825 0bda24234e65ba0c90649a65a0ff4341 298 Gene3D G3DSA:3.90.1200.10 125 249 1.2E-10 T 12-10-2018 UA74_00590 ede5ba507a8699aad11b26e313a67e58 208 PIRSF PIRSF000709 5 174 1.7E-9 T 12-10-2018 UA74_00590 ede5ba507a8699aad11b26e313a67e58 208 SUPERFAMILY SSF53254 3 201 1.31E-39 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_00590 ede5ba507a8699aad11b26e313a67e58 208 Gene3D G3DSA:3.40.50.1240 4 203 1.7E-38 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_00590 ede5ba507a8699aad11b26e313a67e58 208 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 201 4.3E-42 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_00590 ede5ba507a8699aad11b26e313a67e58 208 SMART SM00855 5 160 2.1E-15 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_00590 ede5ba507a8699aad11b26e313a67e58 208 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 UA74_21210 7d1dfb9e6ab01a97cca7a5edda94ceea 439 SUPERFAMILY SSF53335 159 438 7.59E-66 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_21210 7d1dfb9e6ab01a97cca7a5edda94ceea 439 PIRSF PIRSF003085 40 439 1.4E-114 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 UA74_21210 7d1dfb9e6ab01a97cca7a5edda94ceea 439 Gene3D G3DSA:3.40.50.150 157 439 1.4E-91 T 12-10-2018 UA74_21210 7d1dfb9e6ab01a97cca7a5edda94ceea 439 Pfam PF02353 Mycolic acid cyclopropane synthetase 152 433 7.4E-84 T 12-10-2018 UA74_13525 7408e84c67fd0d34c039cb77f1e3566c 329 SUPERFAMILY SSF51735 115 270 3.82E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_13525 7408e84c67fd0d34c039cb77f1e3566c 329 Gene3D G3DSA:3.40.50.720 123 295 1.5E-92 T 12-10-2018 UA74_13525 7408e84c67fd0d34c039cb77f1e3566c 329 SUPERFAMILY SSF50129 2 142 2.28E-33 T 12-10-2018 IPR011032 GroES-like superfamily UA74_13525 7408e84c67fd0d34c039cb77f1e3566c 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 2.0E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_13525 7408e84c67fd0d34c039cb77f1e3566c 329 Pfam PF00107 Zinc-binding dehydrogenase 154 269 1.5E-28 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_13525 7408e84c67fd0d34c039cb77f1e3566c 329 SMART SM00829 13 325 7.3E-43 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_13525 7408e84c67fd0d34c039cb77f1e3566c 329 Gene3D G3DSA:3.90.180.10 8 322 1.5E-92 T 12-10-2018 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 Gene3D G3DSA:1.10.630.10 2 400 2.6E-123 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 140 156 7.0E-60 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 194 216 7.0E-60 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 93 104 7.0E-60 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 273 284 7.0E-60 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 291 318 7.0E-60 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 157 172 7.0E-60 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 319 334 7.0E-60 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 340 349 7.0E-60 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00359 B-class P450 signature 349 360 7.0E-60 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00385 P450 superfamily signature 273 284 2.0E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00385 P450 superfamily signature 340 349 2.0E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00385 P450 superfamily signature 349 360 2.0E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 PRINTS PR00385 P450 superfamily signature 238 255 2.0E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 Pfam PF00067 Cytochrome P450 86 370 3.5E-28 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_05855 aec8b2acd4cf00de609d08bb239b4a47 400 SUPERFAMILY SSF48264 9 400 1.28E-98 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.30.70.3290 7414 7840 7.8E-159 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF55048 7619 7684 6.54E-14 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 1424 1634 6.04E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.50.720 6388 6855 3.4E-119 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.50.720 2981 3419 3.6E-119 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF55048 2475 2536 5.1E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 8140 8308 2.6E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6903 6918 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00825 Beta-ketoacyl synthase 3530 3956 1.1E-225 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00825 Beta-ketoacyl synthase 1801 2227 5.9E-225 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00825 Beta-ketoacyl synthase 5227 5653 5.6E-227 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00825 Beta-ketoacyl synthase 6973 7399 9.1E-222 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00825 Beta-ketoacyl synthase 35 461 4.7E-222 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 6595 6847 3.48E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00826 4430 4590 5.7E-75 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00826 2706 2867 8.8E-80 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00826 6117 6274 2.0E-73 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00826 945 1110 1.9E-82 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00826 7863 8025 3.9E-45 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7498 7793 2.3E-121 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5755 6052 8.0E-114 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 581 878 7.8E-118 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4059 4365 8.7E-107 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2338 2641 2.3E-112 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1736 1751 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF47336 6871 6986 4.97E-22 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1425 1605 6.8E-51 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3157 3337 3.5E-58 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4854 5031 6.1E-53 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6596 6776 3.0E-54 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8323 8503 3.8E-61 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 1223 1409 3.94E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF47336 3431 3543 1.44E-22 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF53901 1796 2171 6.38E-101 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 3154 3409 4.89E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.10.129.110 4419 4704 1.3E-104 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.10.129.110 7852 8134 4.5E-76 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.10.129.110 2695 2980 1.3E-112 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.10.129.110 6106 6387 6.7E-104 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.10.129.110 934 1222 4.0E-108 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF53901 5222 5597 1.06E-105 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF55048 708 769 6.67E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 8323 8578 3.45E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF47336 8598 8683 1.2E-19 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.366.10 4057 4368 4.1E-160 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.366.10 579 881 2.1E-165 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.366.10 2336 2644 3.5E-162 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.366.10 5753 6055 5.4E-161 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.366.10 7496 7796 7.8E-159 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.30.70.3290 5667 6097 5.4E-161 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 4853 5063 1.96E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 4647 4839 1.42E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF14765 Polyketide synthase dehydratase 7863 8129 4.9E-36 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF14765 Polyketide synthase dehydratase 6117 6385 8.8E-54 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF14765 Polyketide synthase dehydratase 4430 4696 9.9E-58 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF14765 Polyketide synthase dehydratase 2706 2978 2.0E-57 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF14765 Polyketide synthase dehydratase 945 1217 6.0E-56 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF53901 30 398 2.09E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.30.70.3290 494 926 2.1E-165 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:1.10.1200.10 8586 8680 4.3E-30 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:1.10.1200.10 3420 3511 1.2E-32 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:1.10.1200.10 1692 1783 1.1E-34 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00698 Acyl transferase domain 2338 2659 4.2E-52 T 12-10-2018 IPR014043 Acyl transferase UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00698 Acyl transferase domain 5755 6070 1.3E-53 T 12-10-2018 IPR014043 Acyl transferase UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00698 Acyl transferase domain 4059 4383 3.7E-50 T 12-10-2018 IPR014043 Acyl transferase UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00698 Acyl transferase domain 580 895 7.1E-52 T 12-10-2018 IPR014043 Acyl transferase UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00698 Acyl transferase domain 7497 7801 7.9E-92 T 12-10-2018 IPR014043 Acyl transferase UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF55048 4186 4247 4.45E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.50.720 8141 8582 8.1E-119 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.50.720 1228 1686 9.5E-122 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF08990 Erythronolide synthase docking 3 26 1.0E-10 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF52151 4055 4337 7.06E-67 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM01294 8605 8672 0.0011 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM01294 1710 1777 8.6E-5 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM01294 5135 5202 5.1E-6 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM01294 3438 3505 1.2E-5 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM01294 6877 6944 4.0E-5 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 6390 6583 1.81E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF47336 1706 1814 1.07E-25 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1962 1978 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3906 4022 3.5E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5603 5718 4.6E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 7349 7463 3.4E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2177 2299 6.6E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 535 2.6E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF47336 5128 5240 3.4E-22 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 7134 7150 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5388 5404 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:1.10.1200.10 5114 5207 1.9E-33 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:1.10.1200.10 6856 6948 2.0E-33 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.30.70.3290 2249 2687 3.5E-162 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF52151 7495 7782 1.46E-67 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.30.70.3290 3974 4411 4.1E-160 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF52151 5752 6045 6.54E-69 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3464 3479 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.50.720 4705 5101 2.9E-114 T 12-10-2018 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.47.10 1794 2238 5.6E-186 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.47.10 24 489 3.7E-188 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.47.10 6962 7413 9.4E-189 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.47.10 3520 3973 2.7E-189 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5225 5475 1.4E-91 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1799 2049 2.2E-89 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 283 7.7E-91 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3528 3778 9.9E-90 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6971 7221 2.9E-92 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Gene3D G3DSA:3.40.47.10 5221 5657 1.3E-187 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF51735 2987 3146 1.46E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF52151 578 867 1.46E-69 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 7229 7346 5.4E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 5.2E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2057 2174 2.5E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5483 5600 1.5E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3786 3903 2.4E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00823 Phosphopantetheine attachment site 3437 3509 8.0E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00823 Phosphopantetheine attachment site 1709 1781 7.4E-32 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00823 Phosphopantetheine attachment site 6876 6948 4.8E-31 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00823 Phosphopantetheine attachment site 5134 5206 2.6E-31 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SMART SM00823 Phosphopantetheine attachment site 8604 8676 8.4E-28 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF08659 KR domain 1425 1604 1.8E-53 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF08659 KR domain 6596 6774 3.1E-56 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF08659 KR domain 4854 5029 3.0E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF08659 KR domain 3157 3336 5.2E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF08659 KR domain 8324 8502 4.5E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 ProSitePatterns PS00012 Phosphopantetheine attachment site. 8631 8646 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF53901 6969 7343 1.41E-103 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5161 5176 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00550 Phosphopantetheine attachment site 5137 5202 9.2E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00550 Phosphopantetheine attachment site 1711 1777 4.5E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00550 Phosphopantetheine attachment site 8606 8672 1.8E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00550 Phosphopantetheine attachment site 3439 3505 5.9E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 Pfam PF00550 Phosphopantetheine attachment site 6879 6944 1.2E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF55048 5886 5947 1.7E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF53901 3525 3899 1.22E-105 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16485 0f6ec7f3972887f96c28297014684ce5 8757 SUPERFAMILY SSF52151 2336 2635 2.2E-67 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_07805 4551636991d1ba25fcc6693fa930a5b2 559 Gene3D G3DSA:1.20.1530.20 3 408 1.4E-7 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily UA74_07805 4551636991d1ba25fcc6693fa930a5b2 559 Pfam PF00999 Sodium/hydrogen exchanger family 8 403 2.4E-51 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 UA74_07805 4551636991d1ba25fcc6693fa930a5b2 559 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 10 465 1.1E-100 T 12-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 UA74_26755 a07a517ef3892b0b177854ed761a06e7 278 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 273 25.417 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_26755 a07a517ef3892b0b177854ed761a06e7 278 SUPERFAMILY SSF56104 1 276 9.48E-95 T 12-10-2018 UA74_26755 a07a517ef3892b0b177854ed761a06e7 278 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 276 4.9E-67 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 UA74_26755 a07a517ef3892b0b177854ed761a06e7 278 Gene3D G3DSA:3.30.470.20 85 229 2.5E-55 T 12-10-2018 UA74_26755 a07a517ef3892b0b177854ed761a06e7 278 Gene3D G3DSA:3.30.200.20 1 84 1.4E-28 T 12-10-2018 UA74_26755 a07a517ef3892b0b177854ed761a06e7 278 Pfam PF01259 SAICAR synthetase 3 248 8.2E-95 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_25050 cc2d618b7ca4ec72e7616cc9b1d73255 418 Gene3D G3DSA:1.20.1740.10 12 415 7.5E-10 T 12-10-2018 UA74_07705 e3c9ab362615b522f1b7646f9d738b94 315 Pfam PF00005 ABC transporter 22 165 4.8E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_07705 e3c9ab362615b522f1b7646f9d738b94 315 Gene3D G3DSA:3.40.50.300 2 235 4.1E-60 T 12-10-2018 UA74_07705 e3c9ab362615b522f1b7646f9d738b94 315 SUPERFAMILY SSF52540 4 228 3.73E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07705 e3c9ab362615b522f1b7646f9d738b94 315 SMART SM00382 30 237 4.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_07705 e3c9ab362615b522f1b7646f9d738b94 315 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_09390 90bac8355431a6f17569e2cbf61e6fc8 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.0E-38 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_09390 90bac8355431a6f17569e2cbf61e6fc8 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 8.0E-21 T 12-10-2018 UA74_09390 90bac8355431a6f17569e2cbf61e6fc8 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_09390 90bac8355431a6f17569e2cbf61e6fc8 89 Gene3D G3DSA:1.10.287.10 2 89 5.8E-34 T 12-10-2018 UA74_09390 90bac8355431a6f17569e2cbf61e6fc8 89 SUPERFAMILY SSF47060 3 89 5.89E-35 T 12-10-2018 IPR009068 S15/NS1, RNA-binding UA74_09390 90bac8355431a6f17569e2cbf61e6fc8 89 Pfam PF00312 Ribosomal protein S15 8 88 4.6E-37 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_09390 90bac8355431a6f17569e2cbf61e6fc8 89 SMART SM01387 8 88 1.7E-50 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_09390 90bac8355431a6f17569e2cbf61e6fc8 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.462 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 Gene3D G3DSA:1.10.630.10 2 404 1.0E-150 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 SUPERFAMILY SSF48264 17 402 5.89E-106 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 Pfam PF00067 Cytochrome P450 175 267 2.8E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 Pfam PF00067 Cytochrome P450 273 372 5.4E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 293 320 7.7E-62 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 275 286 7.7E-62 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 159 174 7.7E-62 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 351 362 7.7E-62 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 142 158 7.7E-62 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 96 107 7.7E-62 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 194 216 7.7E-62 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 342 351 7.7E-62 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09790 cc148c5bda26bf2f9d7eed987b5dff90 404 PRINTS PR00359 B-class P450 signature 321 336 7.7E-62 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_27075 a3f73733bca51229569e69b3ddbe966f 415 PIRSF PIRSF015578 3 399 1.2E-77 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_27075 a3f73733bca51229569e69b3ddbe966f 415 Pfam PF07994 Myo-inositol-1-phosphate synthase 10 385 4.2E-43 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_27075 a3f73733bca51229569e69b3ddbe966f 415 Pfam PF01658 Myo-inositol-1-phosphate synthase 226 330 5.6E-24 T 12-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_27075 a3f73733bca51229569e69b3ddbe966f 415 Gene3D G3DSA:3.40.50.720 13 377 6.9E-124 T 12-10-2018 UA74_27075 a3f73733bca51229569e69b3ddbe966f 415 SUPERFAMILY SSF51735 11 386 1.34E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_27075 a3f73733bca51229569e69b3ddbe966f 415 SUPERFAMILY SSF55347 225 329 2.62E-26 T 12-10-2018 UA74_27075 a3f73733bca51229569e69b3ddbe966f 415 Gene3D G3DSA:3.30.360.10 226 326 6.9E-124 T 12-10-2018 UA74_17005 3757d4cf7ed9afc3eab9782e1480aec4 394 Gene3D G3DSA:3.50.50.60 4 363 1.6E-86 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17005 3757d4cf7ed9afc3eab9782e1480aec4 394 Pfam PF01266 FAD dependent oxidoreductase 4 362 7.0E-61 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_17005 3757d4cf7ed9afc3eab9782e1480aec4 394 SUPERFAMILY SSF54373 223 323 1.12E-11 T 12-10-2018 UA74_17005 3757d4cf7ed9afc3eab9782e1480aec4 394 Gene3D G3DSA:3.30.9.10 90 324 1.6E-86 T 12-10-2018 UA74_17005 3757d4cf7ed9afc3eab9782e1480aec4 394 SUPERFAMILY SSF51905 2 381 4.99E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_03615 37168b6ee6f7317b06db4db54086d013 287 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 102 285 1.7E-56 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UA74_03615 37168b6ee6f7317b06db4db54086d013 287 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 101 278 33.261 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UA74_03615 37168b6ee6f7317b06db4db54086d013 287 SUPERFAMILY SSF53178 102 285 5.1E-65 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 UA74_03615 37168b6ee6f7317b06db4db54086d013 287 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 207 217 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 UA74_03615 37168b6ee6f7317b06db4db54086d013 287 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 114 127 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 UA74_03615 37168b6ee6f7317b06db4db54086d013 287 Gene3D G3DSA:3.40.50.1470 87 287 6.8E-70 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 UA74_03615 37168b6ee6f7317b06db4db54086d013 287 Pfam PF01195 Peptidyl-tRNA hydrolase 103 285 9.1E-55 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UA74_03615 37168b6ee6f7317b06db4db54086d013 287 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 50 86 2.4E-11 T 12-10-2018 IPR019933 DivIVA domain UA74_03615 37168b6ee6f7317b06db4db54086d013 287 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 2.9E-12 T 12-10-2018 IPR019933 DivIVA domain UA74_01140 5466728265d83aeeb7548a6730096cc2 146 SUPERFAMILY SSF49464 54 109 1.77E-5 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily UA74_21660 d11709d56ff1220c09fe76a2c8481505 292 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 211 263 2.0E-5 T 12-10-2018 UA74_21660 d11709d56ff1220c09fe76a2c8481505 292 Pfam PF03601 Conserved hypothetical protein 698 26 275 2.5E-39 T 12-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 UA74_15030 448cbd6657698507997f3972dee5f040 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 1.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15030 448cbd6657698507997f3972dee5f040 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 1.2E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15030 448cbd6657698507997f3972dee5f040 227 Gene3D G3DSA:1.10.357.10 16 219 4.1E-41 T 12-10-2018 UA74_15030 448cbd6657698507997f3972dee5f040 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 74 2.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15030 448cbd6657698507997f3972dee5f040 227 SUPERFAMILY SSF46689 20 91 1.99E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 SUPERFAMILY SSF51905 3 337 6.63E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Gene3D G3DSA:3.30.390.30 341 462 1.1E-32 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PIRSF PIRSF000350 1 457 4.6E-81 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 456 1.7E-20 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Gene3D G3DSA:3.50.50.60 155 273 2.0E-104 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 9.4E-49 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 9.4E-49 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 9.4E-49 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 9.4E-49 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 9.4E-49 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 9.4E-49 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 9.4E-49 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 9.4E-49 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 9.4E-49 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 328 4.1E-56 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 Gene3D G3DSA:3.50.50.60 4 331 2.0E-104 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 4.0E-33 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 4.0E-33 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.0E-33 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 4.0E-33 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 4.0E-33 T 12-10-2018 UA74_26985 e5a007b1bfd2fcc36dfcf49d0d6bbd1e 467 SUPERFAMILY SSF55424 347 461 1.07E-25 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_04275 59e97aa149483ed2f2eed483eda49c78 382 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 59 376 2.8E-68 T 12-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 UA74_04275 59e97aa149483ed2f2eed483eda49c78 382 Gene3D G3DSA:3.40.190.10 165 377 2.9E-102 T 12-10-2018 UA74_04275 59e97aa149483ed2f2eed483eda49c78 382 SUPERFAMILY SSF53850 60 377 5.2E-48 T 12-10-2018 UA74_04275 59e97aa149483ed2f2eed483eda49c78 382 Gene3D G3DSA:3.40.190.10 62 351 2.9E-102 T 12-10-2018 UA74_04275 59e97aa149483ed2f2eed483eda49c78 382 Pfam PF13343 Bacterial extracellular solute-binding protein 107 351 1.3E-27 T 12-10-2018 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PRINTS PR00151 Porphobilinogen deaminase signature 226 243 5.4E-24 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PRINTS PR00151 Porphobilinogen deaminase signature 71 90 5.4E-24 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PRINTS PR00151 Porphobilinogen deaminase signature 138 155 5.4E-24 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PRINTS PR00151 Porphobilinogen deaminase signature 119 136 5.4E-24 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 PIRSF PIRSF001438 1 310 4.7E-104 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Gene3D G3DSA:3.40.190.10 5 210 6.3E-74 T 12-10-2018 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Gene3D G3DSA:3.40.190.10 95 194 6.3E-74 T 12-10-2018 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 301 33.756 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 223 299 3.3E-15 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 SUPERFAMILY SSF53850 3 211 8.47E-66 T 12-10-2018 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 SUPERFAMILY SSF54782 216 304 2.62E-14 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Gene3D G3DSA:3.30.160.40 217 307 2.1E-16 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 207 5.5E-67 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 299 1.1E-89 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02325 5ffd9cdd0648f0acbc1b0e544238fd1d 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 227 243 - T 12-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_21280 6229ecf8605340e5679e9e53e13ae1e7 267 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 127 1.3E-12 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 UA74_21280 6229ecf8605340e5679e9e53e13ae1e7 267 SUPERFAMILY SSF55961 3 136 1.1E-19 T 12-10-2018 UA74_21280 6229ecf8605340e5679e9e53e13ae1e7 267 Gene3D G3DSA:3.30.530.20 1 138 1.4E-31 T 12-10-2018 IPR023393 START-like domain superfamily UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 PIRSF PIRSF000332 4 440 9.0E-54 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 SUPERFAMILY SSF51905 150 312 8.7E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 SUPERFAMILY SSF51905 7 203 1.02E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 Gene3D G3DSA:3.50.50.60 2 376 1.1E-77 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 Pfam PF00743 Flavin-binding monooxygenase-like 7 382 5.8E-48 T 12-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 6 22 6.9E-21 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 185 200 6.9E-21 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 78 93 6.9E-21 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 158 172 6.9E-21 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 296 323 6.9E-21 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_16745 47711a2052c1c8a5a2ec00bf2f90aa1a 448 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 54 72 6.9E-21 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_00810 d12f68b6be5ac17c9853f11ef32fb3e4 693 Gene3D G3DSA:3.40.50.12780 83 536 1.7E-68 T 12-10-2018 UA74_00810 d12f68b6be5ac17c9853f11ef32fb3e4 693 Gene3D G3DSA:3.30.300.30 539 660 4.9E-10 T 12-10-2018 UA74_00810 d12f68b6be5ac17c9853f11ef32fb3e4 693 SUPERFAMILY SSF56801 50 643 2.62E-124 T 12-10-2018 UA74_00810 d12f68b6be5ac17c9853f11ef32fb3e4 693 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 49 104 7.8E-14 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 UA74_00810 d12f68b6be5ac17c9853f11ef32fb3e4 693 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 8 666 3.1E-243 T 12-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 UA74_00810 d12f68b6be5ac17c9853f11ef32fb3e4 693 ProSitePatterns PS00455 Putative AMP-binding domain signature. 284 295 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_00810 d12f68b6be5ac17c9853f11ef32fb3e4 693 Pfam PF00501 AMP-binding enzyme 111 541 2.9E-52 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_29580 23808e50c2b0073e85d19d442533d361 164 Gene3D G3DSA:1.10.10.10 18 162 9.1E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_29580 23808e50c2b0073e85d19d442533d361 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_29580 23808e50c2b0073e85d19d442533d361 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 1.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_29580 23808e50c2b0073e85d19d442533d361 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 140 160 1.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_29580 23808e50c2b0073e85d19d442533d361 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 1.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_29580 23808e50c2b0073e85d19d442533d361 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 1.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_29580 23808e50c2b0073e85d19d442533d361 164 SUPERFAMILY SSF46785 33 163 1.26E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_29580 23808e50c2b0073e85d19d442533d361 164 Pfam PF12802 MarR family 56 114 1.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_29580 23808e50c2b0073e85d19d442533d361 164 SMART SM00347 50 150 4.4E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 Gene3D G3DSA:3.40.47.10 639 774 8.3E-9 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 Gene3D G3DSA:3.40.47.10 6 230 1.0E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 SUPERFAMILY SSF53901 599 738 9.88E-18 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 217 7.4E-34 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 464 623 7.5E-13 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 SUPERFAMILY SSF53901 415 632 1.4E-29 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 Gene3D G3DSA:3.40.47.10 231 392 1.1E-44 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 Gene3D G3DSA:3.40.47.10 402 633 1.9E-34 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 SMART SM00825 Beta-ketoacyl synthase 6 405 4.6E-15 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 SUPERFAMILY SSF53901 4 339 1.47E-57 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05730 25ffe097cf5cd6cf1e3dc70510efc07e 775 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 227 341 2.6E-34 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_25080 25333ceceb1fa296589806a2f216c206 239 Gene3D G3DSA:3.30.930.10 1 205 4.9E-78 T 12-10-2018 UA74_25080 25333ceceb1fa296589806a2f216c206 239 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 25 195 5.7E-40 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_25080 25333ceceb1fa296589806a2f216c206 239 SUPERFAMILY SSF55681 3 205 2.15E-65 T 12-10-2018 UA74_25080 25333ceceb1fa296589806a2f216c206 239 PIRSF PIRSF016262 2 217 1.1E-60 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_25080 25333ceceb1fa296589806a2f216c206 239 Pfam PF03099 Biotin/lipoate A/B protein ligase family 49 159 9.8E-10 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UA74_25080 25333ceceb1fa296589806a2f216c206 239 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 70 122 5.0E-18 T 12-10-2018 UA74_25080 25333ceceb1fa296589806a2f216c206 239 Hamap MF_00013 Octanoyltransferase [lipB]. 1 207 33.536 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_25080 25333ceceb1fa296589806a2f216c206 239 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 66 81 - T 12-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UA74_15135 98af1eabc5128acf597c656d43fd03e4 427 Pfam PF13186 Iron-sulfur cluster-binding domain 290 352 1.7E-9 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain UA74_15135 98af1eabc5128acf597c656d43fd03e4 427 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 286 372 2.8E-9 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain UA74_15135 98af1eabc5128acf597c656d43fd03e4 427 SUPERFAMILY SSF102114 56 361 2.49E-43 T 12-10-2018 UA74_15135 98af1eabc5128acf597c656d43fd03e4 427 Pfam PF13353 4Fe-4S single cluster domain 60 173 2.1E-5 T 12-10-2018 UA74_15135 98af1eabc5128acf597c656d43fd03e4 427 Gene3D G3DSA:3.20.20.70 44 342 5.4E-34 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_15135 98af1eabc5128acf597c656d43fd03e4 427 SMART SM00729 52 261 9.8E-4 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_15135 98af1eabc5128acf597c656d43fd03e4 427 Pfam PF04055 Radical SAM superfamily 59 221 9.0E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_04095 2b743075ea924da0330267e3fdbced98 472 Gene3D G3DSA:3.40.50.1010 41 187 4.7E-18 T 12-10-2018 UA74_04095 2b743075ea924da0330267e3fdbced98 472 Gene3D G3DSA:3.40.50.300 260 467 1.5E-52 T 12-10-2018 UA74_04095 2b743075ea924da0330267e3fdbced98 472 Pfam PF13638 PIN domain 47 185 3.7E-27 T 12-10-2018 IPR002716 PIN domain UA74_04095 2b743075ea924da0330267e3fdbced98 472 SUPERFAMILY SSF88723 46 179 4.07E-9 T 12-10-2018 IPR029060 PIN-like domain superfamily UA74_04095 2b743075ea924da0330267e3fdbced98 472 Pfam PF02562 PhoH-like protein 262 466 4.3E-53 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 UA74_04095 2b743075ea924da0330267e3fdbced98 472 SUPERFAMILY SSF52540 260 422 3.56E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04095 2b743075ea924da0330267e3fdbced98 472 SMART SM00670 45 172 3.7E-19 T 12-10-2018 IPR002716 PIN domain UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 SUPERFAMILY SSF51735 5 240 2.88E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.4E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.4E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.4E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.4E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.4E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 Gene3D G3DSA:3.40.50.720 1 243 3.9E-77 T 12-10-2018 UA74_06810 9366db6a56c6f0f61113ba51d49502fd 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 240 1.8E-58 T 12-10-2018 UA74_05180 081aee843a0644fc02119c7fe2e73d3c 349 SUPERFAMILY SSF53335 142 236 2.05E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_05180 081aee843a0644fc02119c7fe2e73d3c 349 Pfam PF05175 Methyltransferase small domain 162 235 2.3E-8 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 UA74_05180 081aee843a0644fc02119c7fe2e73d3c 349 Gene3D G3DSA:3.40.50.150 146 274 3.3E-16 T 12-10-2018 UA74_00260 8c7b0b11390410b6c283c7e3eabbbe9f 260 SUPERFAMILY SSF161098 59 246 2.62E-31 T 12-10-2018 IPR035906 MetI-like superfamily UA74_00260 8c7b0b11390410b6c283c7e3eabbbe9f 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 251 6.9E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_00260 8c7b0b11390410b6c283c7e3eabbbe9f 260 Gene3D G3DSA:1.10.3720.10 55 254 3.7E-29 T 12-10-2018 IPR035906 MetI-like superfamily UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 SUPERFAMILY SSF52317 6 229 1.99E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00097 Anthranilate synthase component II signature 169 182 1.3E-5 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00097 Anthranilate synthase component II signature 80 91 1.3E-5 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00097 Anthranilate synthase component II signature 53 62 1.3E-5 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 SUPERFAMILY SSF52402 185 444 2.09E-57 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 2.9E-8 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 2.9E-8 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 2.9E-8 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 1.8E-6 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 1.8E-6 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 1.8E-6 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 195 7.0E-70 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 Gene3D G3DSA:3.40.50.880 6 201 2.1E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 Pfam PF02540 NAD synthase 217 287 3.7E-5 T 12-10-2018 IPR022310 NAD/GMP synthase UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 SUPERFAMILY SSF54810 403 524 2.75E-46 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 524 53.095 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 Gene3D G3DSA:3.30.300.10 404 524 1.3E-51 T 12-10-2018 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 Pfam PF00958 GMP synthase C terminal domain 431 523 2.4E-38 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 Gene3D G3DSA:3.40.50.620 202 403 8.2E-71 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 Pfam PF00117 Glutamine amidotransferase class-I 11 191 1.0E-39 T 12-10-2018 IPR017926 Glutamine amidotransferase UA74_27830 77e7cb38db8fa6edf9e697241c388d4e 524 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 524 6.8E-145 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UA74_19475 23340152a087a6bb1548d5609e8420ea 377 Pfam PF01758 Sodium Bile acid symporter family 61 257 4.8E-62 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 UA74_19475 23340152a087a6bb1548d5609e8420ea 377 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 16 344 5.2E-132 T 12-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 UA74_19475 23340152a087a6bb1548d5609e8420ea 377 PIRSF PIRSF005508 2 359 9.5E-136 T 12-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 UA74_19475 23340152a087a6bb1548d5609e8420ea 377 Gene3D G3DSA:1.20.1530.20 15 353 2.3E-24 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily UA74_07495 8891481030c18dc01446f64a1aebe70d 746 PIRSF PIRSF000463 18 746 3.6E-249 T 12-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_07495 8891481030c18dc01446f64a1aebe70d 746 SUPERFAMILY SSF81296 28 138 1.01E-11 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_07495 8891481030c18dc01446f64a1aebe70d 746 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 130 743 8.9E-247 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 UA74_07495 8891481030c18dc01446f64a1aebe70d 746 Gene3D G3DSA:2.60.40.1180 643 746 7.1E-35 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_07495 8891481030c18dc01446f64a1aebe70d 746 Pfam PF00128 Alpha amylase, catalytic domain 296 363 1.0E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07495 8891481030c18dc01446f64a1aebe70d 746 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 146 232 3.0E-14 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_07495 8891481030c18dc01446f64a1aebe70d 746 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 648 745 1.1E-16 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 UA74_07495 8891481030c18dc01446f64a1aebe70d 746 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 122 746 40.651 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 UA74_07495 8891481030c18dc01446f64a1aebe70d 746 SUPERFAMILY SSF51011 644 745 1.26E-27 T 12-10-2018 UA74_07495 8891481030c18dc01446f64a1aebe70d 746 Gene3D G3DSA:3.20.20.80 248 642 9.5E-164 T 12-10-2018 UA74_07495 8891481030c18dc01446f64a1aebe70d 746 SUPERFAMILY SSF51445 206 639 3.0E-109 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07495 8891481030c18dc01446f64a1aebe70d 746 Gene3D G3DSA:2.60.40.10 14 246 1.4E-54 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_07495 8891481030c18dc01446f64a1aebe70d 746 SMART SM00642 275 615 1.9E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_04620 c0fbcd01ba4f638c8037c6d6f9f4d7ca 427 Pfam PF01547 Bacterial extracellular solute-binding protein 78 329 7.9E-23 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_04620 c0fbcd01ba4f638c8037c6d6f9f4d7ca 427 SUPERFAMILY SSF53850 43 397 7.67E-61 T 12-10-2018 UA74_04620 c0fbcd01ba4f638c8037c6d6f9f4d7ca 427 Gene3D G3DSA:3.40.190.10 154 397 1.5E-69 T 12-10-2018 UA74_04620 c0fbcd01ba4f638c8037c6d6f9f4d7ca 427 Gene3D G3DSA:3.40.190.10 69 376 1.5E-69 T 12-10-2018 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 Gene3D G3DSA:3.40.50.720 5 206 3.9E-69 T 12-10-2018 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 SUPERFAMILY SSF51735 11 196 2.35E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 PIRSF PIRSF500136 5 445 8.8E-114 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 Gene3D G3DSA:3.40.50.720 240 450 5.7E-62 T 12-10-2018 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 PIRSF PIRSF000124 10 450 3.1E-106 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 SMART SM00984 330 432 2.3E-26 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 SUPERFAMILY SSF52413 318 437 1.14E-25 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 427 1.4E-104 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 303 1.0E-20 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 SUPERFAMILY SSF48179 209 305 9.18E-23 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 330 427 4.1E-21 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_17470 15b8cb1f385a94086b3b5b8826c5b7c6 450 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 188 5.1E-44 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_02490 4b6fac551358a1c2b7ede0c21dcca660 290 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 128 148 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 UA74_02490 4b6fac551358a1c2b7ede0c21dcca660 290 Gene3D G3DSA:3.90.226.10 6 227 7.7E-71 T 12-10-2018 UA74_02490 4b6fac551358a1c2b7ede0c21dcca660 290 TIGRFAM TIGR01929 menB: naphthoate synthase 21 286 1.2E-128 T 12-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 UA74_02490 4b6fac551358a1c2b7ede0c21dcca660 290 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 15 289 53.656 T 12-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 UA74_02490 4b6fac551358a1c2b7ede0c21dcca660 290 SUPERFAMILY SSF52096 16 286 9.68E-77 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_02490 4b6fac551358a1c2b7ede0c21dcca660 290 Gene3D G3DSA:1.10.12.10 228 278 4.3E-25 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal UA74_02490 4b6fac551358a1c2b7ede0c21dcca660 290 Pfam PF00378 Enoyl-CoA hydratase/isomerase 29 284 1.9E-76 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UA74_04995 24dc9336dd59ecc346f85c81c68b391a 309 Pfam PF13462 Thioredoxin 129 274 5.5E-19 T 12-10-2018 IPR012336 Thioredoxin-like fold UA74_04995 24dc9336dd59ecc346f85c81c68b391a 309 SUPERFAMILY SSF52833 127 304 1.77E-26 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_04995 24dc9336dd59ecc346f85c81c68b391a 309 Gene3D G3DSA:3.40.30.10 100 306 8.8E-44 T 12-10-2018 UA74_18885 0f6a28f0b834f5f2ea8303061e09ce73 223 Pfam PF12802 MarR family 37 98 1.9E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_18885 0f6a28f0b834f5f2ea8303061e09ce73 223 SMART SM00347 32 134 9.6E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_18885 0f6a28f0b834f5f2ea8303061e09ce73 223 SUPERFAMILY SSF46785 4 150 2.68E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18885 0f6a28f0b834f5f2ea8303061e09ce73 223 Gene3D G3DSA:1.10.10.10 4 151 2.2E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21915 eb4963adc3d1c6db85a63ff5d08fe0a4 178 Pfam PF05145 Transition state regulatory protein AbrB 19 174 1.9E-28 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 UA74_21915 eb4963adc3d1c6db85a63ff5d08fe0a4 178 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 21 173 4.0E-31 T 12-10-2018 IPR017516 AbrB duplication UA74_08235 6b29de206d64f898ebb28c0e501a78d3 490 SUPERFAMILY SSF53720 75 487 3.37E-116 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_08235 6b29de206d64f898ebb28c0e501a78d3 490 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 76 487 42.005 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_08235 6b29de206d64f898ebb28c0e501a78d3 490 Gene3D G3DSA:3.40.605.10 93 482 1.3E-161 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_08235 6b29de206d64f898ebb28c0e501a78d3 490 Pfam PF00171 Aldehyde dehydrogenase family 68 362 2.6E-15 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_08235 6b29de206d64f898ebb28c0e501a78d3 490 Gene3D G3DSA:3.40.309.10 297 445 1.3E-161 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_08235 6b29de206d64f898ebb28c0e501a78d3 490 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 394 415 - T 12-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_08235 6b29de206d64f898ebb28c0e501a78d3 490 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 84 477 4.5E-145 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_00085 02b668c73dae4117052324f2bbc12322 184 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 64 81 - T 12-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 UA74_00085 02b668c73dae4117052324f2bbc12322 184 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 16 178 2.4E-44 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UA74_00085 02b668c73dae4117052324f2bbc12322 184 Gene3D G3DSA:2.40.100.10 11 180 1.5E-72 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily UA74_00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 69 81 3.6E-25 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UA74_00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 124 136 3.6E-25 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UA74_00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 137 152 3.6E-25 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UA74_00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 28 43 3.6E-25 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UA74_00085 02b668c73dae4117052324f2bbc12322 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 109 124 3.6E-25 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UA74_00085 02b668c73dae4117052324f2bbc12322 184 PIRSF PIRSF001467 5 183 7.0E-56 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 UA74_00085 02b668c73dae4117052324f2bbc12322 184 SUPERFAMILY SSF50891 14 179 9.06E-61 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 SUPERFAMILY SSF56014 166 325 2.09E-44 T 12-10-2018 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 Gene3D G3DSA:3.30.413.10 158 336 1.7E-121 T 12-10-2018 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 467 483 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 166 316 9.1E-37 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 Gene3D G3DSA:3.30.413.10 415 561 9.9E-43 T 12-10-2018 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 SUPERFAMILY SSF55124 15 165 1.23E-38 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 PRINTS PR00397 Sirohaem Fe-binding site signature 418 436 5.6E-10 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 PRINTS PR00397 Sirohaem Fe-binding site signature 467 485 5.6E-10 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 Gene3D G3DSA:3.90.480.20 28 403 1.7E-121 T 12-10-2018 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 341 405 2.3E-12 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 95 156 4.4E-19 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 418 555 1.6E-10 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 SUPERFAMILY SSF56014 414 560 3.93E-37 T 12-10-2018 UA74_24525 8731a7cb1aeab452e4f7002f83a58246 561 SUPERFAMILY SSF55124 334 411 4.74E-17 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 SUPERFAMILY SSF51445 407 739 6.94E-103 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_18510 8520d18b7868f711e61f79e8507465f2 824 Gene3D G3DSA:3.20.20.70 393 709 1.8E-126 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 Gene3D G3DSA:2.70.98.60 256 392 2.1E-28 T 12-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 PRINTS PR00743 Glycosyl hydrolase family 36 signature 411 425 8.4E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 PRINTS PR00743 Glycosyl hydrolase family 36 signature 326 341 8.4E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 PRINTS PR00743 Glycosyl hydrolase family 36 signature 439 454 8.4E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 PRINTS PR00743 Glycosyl hydrolase family 36 signature 489 511 8.4E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 PRINTS PR00743 Glycosyl hydrolase family 36 signature 622 638 8.4E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 PRINTS PR00743 Glycosyl hydrolase family 36 signature 597 613 8.4E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 PRINTS PR00743 Glycosyl hydrolase family 36 signature 547 562 8.4E-41 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 123 369 8.5E-38 T 12-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 ProSitePatterns PS00512 Alpha-galactosidase signature. 440 456 - T 12-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_18510 8520d18b7868f711e61f79e8507465f2 824 Pfam PF02065 Melibiase 374 712 2.4E-121 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 3.0E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 SMART SM00421 159 216 9.1E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 Pfam PF00072 Response regulator receiver domain 7 123 1.0E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 SUPERFAMILY SSF52172 4 140 4.13E-31 T 12-10-2018 IPR011006 CheY-like superfamily UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 Gene3D G3DSA:3.40.50.12740 5 220 1.5E-61 T 12-10-2018 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 SUPERFAMILY SSF46894 144 218 1.22E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 SMART SM00448 5 122 2.9E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 1.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 1.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16405 65b3cd1fe2cfcf630a630de67f7a27d3 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 1.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_26785 2ec33be41b8993f8808585859a688203 1134 SUPERFAMILY SSF88946 8 107 1.57E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_26785 2ec33be41b8993f8808585859a688203 1134 Gene3D G3DSA:1.10.10.10 119 186 2.3E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26785 2ec33be41b8993f8808585859a688203 1134 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 184 3.3E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_26785 2ec33be41b8993f8808585859a688203 1134 Gene3D G3DSA:1.10.1740.10 7 115 6.7E-16 T 12-10-2018 UA74_26785 2ec33be41b8993f8808585859a688203 1134 Gene3D G3DSA:1.10.10.1320 201 250 7.0E-6 T 12-10-2018 UA74_26785 2ec33be41b8993f8808585859a688203 1134 Pfam PF04542 Sigma-70 region 2 31 99 1.8E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_26785 2ec33be41b8993f8808585859a688203 1134 SUPERFAMILY SSF88659 123 184 6.17E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_26785 2ec33be41b8993f8808585859a688203 1134 Pfam PF13490 Putative zinc-finger 198 232 1.4E-7 T 12-10-2018 IPR027383 Putative zinc-finger UA74_06845 5aca50478a19dddc51853fd8a8727a10 64 Gene3D G3DSA:3.30.70.20 1 64 8.5E-17 T 12-10-2018 UA74_06845 5aca50478a19dddc51853fd8a8727a10 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 5.2E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_06845 5aca50478a19dddc51853fd8a8727a10 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 5.2E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_06845 5aca50478a19dddc51853fd8a8727a10 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 5.2E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_06845 5aca50478a19dddc51853fd8a8727a10 64 Pfam PF13459 4Fe-4S single cluster domain 3 61 1.0E-11 T 12-10-2018 UA74_06845 5aca50478a19dddc51853fd8a8727a10 64 SUPERFAMILY SSF54862 2 62 1.26E-11 T 12-10-2018 UA74_22660 035138002ce5d2840012190b50be413f 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 313 8.5E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_22660 035138002ce5d2840012190b50be413f 340 SUPERFAMILY SSF52540 20 268 1.01E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22660 035138002ce5d2840012190b50be413f 340 Gene3D G3DSA:3.40.50.300 17 339 4.3E-93 T 12-10-2018 UA74_22660 035138002ce5d2840012190b50be413f 340 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22660 035138002ce5d2840012190b50be413f 340 Pfam PF00005 ABC transporter 40 197 1.1E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_22660 035138002ce5d2840012190b50be413f 340 SMART SM00382 48 247 1.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_22660 035138002ce5d2840012190b50be413f 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 333 4.4E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_26905 4990e34b3faacfef105f63e396ecef27 569 Gene3D G3DSA:1.10.3720.10 306 565 9.0E-36 T 12-10-2018 IPR035906 MetI-like superfamily UA74_26905 4990e34b3faacfef105f63e396ecef27 569 SUPERFAMILY SSF161098 302 558 1.12E-39 T 12-10-2018 IPR035906 MetI-like superfamily UA74_26905 4990e34b3faacfef105f63e396ecef27 569 Gene3D G3DSA:1.10.3720.10 13 289 1.4E-44 T 12-10-2018 IPR035906 MetI-like superfamily UA74_26905 4990e34b3faacfef105f63e396ecef27 569 SUPERFAMILY SSF161098 7 283 3.55E-49 T 12-10-2018 IPR035906 MetI-like superfamily UA74_26905 4990e34b3faacfef105f63e396ecef27 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 382 558 3.3E-9 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_26905 4990e34b3faacfef105f63e396ecef27 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 283 7.7E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:3.40.50.12780 688 1092 2.2E-129 T 12-10-2018 UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Pfam PF00550 Phosphopantetheine attachment site 1211 1274 7.1E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SUPERFAMILY SSF56801 678 1221 2.49E-150 T 12-10-2018 UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SUPERFAMILY SSF52777 429 662 4.56E-26 T 12-10-2018 UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 719 1122 2.9E-124 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:3.40.50.1820 1198 1308 7.1E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Pfam PF00501 AMP-binding enzyme 698 1098 1.7E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:3.30.559.30 450 670 2.4E-39 T 12-10-2018 UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Pfam PF13193 AMP-binding enzyme C-terminal domain 1106 1181 2.4E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SUPERFAMILY SSF47336 1202 1275 9.55E-18 T 12-10-2018 IPR036736 ACP-like superfamily UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:3.30.300.30 1093 1196 8.5E-32 T 12-10-2018 UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 ProSitePatterns PS00455 Putative AMP-binding domain signature. 850 861 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Pfam PF00668 Condensation domain 53 275 8.5E-27 T 12-10-2018 IPR001242 Condensation domain UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Pfam PF00668 Condensation domain 448 588 2.4E-10 T 12-10-2018 IPR001242 Condensation domain UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SUPERFAMILY SSF52777 58 254 1.89E-30 T 12-10-2018 UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 Gene3D G3DSA:3.30.559.10 58 277 8.6E-55 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_06490 a4b875980fb8b6e3f5c52ac4f0a7cd88 1400 SMART SM00823 Phosphopantetheine attachment site 1209 1278 2.2E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_05860 d0a9dc9ef588325ca48e1dc18058430c 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 3.0E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05860 d0a9dc9ef588325ca48e1dc18058430c 197 SUPERFAMILY SSF46689 9 87 5.99E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_05860 d0a9dc9ef588325ca48e1dc18058430c 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.8E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05860 d0a9dc9ef588325ca48e1dc18058430c 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.8E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05860 d0a9dc9ef588325ca48e1dc18058430c 197 SUPERFAMILY SSF48498 81 182 3.34E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_05860 d0a9dc9ef588325ca48e1dc18058430c 197 Gene3D G3DSA:1.10.357.10 4 188 4.9E-42 T 12-10-2018 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 Pfam PF00067 Cytochrome P450 13 437 9.5E-84 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 SUPERFAMILY SSF48264 11 451 1.1E-111 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00385 P450 superfamily signature 402 413 1.9E-13 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00385 P450 superfamily signature 266 283 1.9E-13 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00385 P450 superfamily signature 318 329 1.9E-13 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00385 P450 superfamily signature 393 402 1.9E-13 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 357 381 5.4E-23 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 255 272 5.4E-23 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 40 59 5.4E-23 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 275 301 5.4E-23 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 392 402 5.4E-23 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 PRINTS PR00463 E-class P450 group I signature 402 425 5.4E-23 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18595 e8a75a5afacc45052c15dce2d60ff901 455 Gene3D G3DSA:1.10.630.10 12 453 2.3E-120 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_11435 c100392033704c81d4a3e4641758455a 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.0E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_11435 c100392033704c81d4a3e4641758455a 198 SUPERFAMILY SSF48498 81 188 4.45E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_11435 c100392033704c81d4a3e4641758455a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_11435 c100392033704c81d4a3e4641758455a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_11435 c100392033704c81d4a3e4641758455a 198 SUPERFAMILY SSF46689 1 75 1.95E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_11435 c100392033704c81d4a3e4641758455a 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_11435 c100392033704c81d4a3e4641758455a 198 Gene3D G3DSA:1.10.357.10 3 195 1.0E-54 T 12-10-2018 UA74_00970 9906148015ddfa659f55e71ff3fe3037 386 Pfam PF13378 Enolase C-terminal domain-like 154 373 1.9E-37 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_00970 9906148015ddfa659f55e71ff3fe3037 386 SMART SM00922 147 248 2.7E-13 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_00970 9906148015ddfa659f55e71ff3fe3037 386 SUPERFAMILY SSF51604 123 382 2.36E-46 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_00970 9906148015ddfa659f55e71ff3fe3037 386 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 35 123 2.5E-7 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_00970 9906148015ddfa659f55e71ff3fe3037 386 SUPERFAMILY SSF54826 21 123 3.18E-16 T 12-10-2018 UA74_00970 9906148015ddfa659f55e71ff3fe3037 386 Gene3D G3DSA:3.20.20.120 118 381 1.0E-57 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_00970 9906148015ddfa659f55e71ff3fe3037 386 Gene3D G3DSA:3.30.390.10 1 114 2.5E-19 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_07820 1a11b8c5bc0cd5a3faf4d1492148d708 98 SMART SM00357 34 98 8.5E-29 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 UA74_07820 1a11b8c5bc0cd5a3faf4d1492148d708 98 PIRSF PIRSF002599 28 98 3.6E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 UA74_07820 1a11b8c5bc0cd5a3faf4d1492148d708 98 PRINTS PR00050 Cold shock protein signature 56 65 3.3E-16 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_07820 1a11b8c5bc0cd5a3faf4d1492148d708 98 PRINTS PR00050 Cold shock protein signature 71 89 3.3E-16 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_07820 1a11b8c5bc0cd5a3faf4d1492148d708 98 PRINTS PR00050 Cold shock protein signature 35 50 3.3E-16 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_07820 1a11b8c5bc0cd5a3faf4d1492148d708 98 ProSitePatterns PS00352 'Cold-shock' domain signature. 46 65 - T 12-10-2018 IPR019844 Cold-shock conserved site UA74_07820 1a11b8c5bc0cd5a3faf4d1492148d708 98 Pfam PF00313 'Cold-shock' DNA-binding domain 34 97 1.2E-29 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_07820 1a11b8c5bc0cd5a3faf4d1492148d708 98 Gene3D G3DSA:2.40.50.140 32 97 1.8E-29 T 12-10-2018 UA74_07820 1a11b8c5bc0cd5a3faf4d1492148d708 98 SUPERFAMILY SSF50249 30 97 6.86E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_06960 819003a8a61b8eb246ac3a5151abeb08 314 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 41 94 6.6E-7 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_06960 819003a8a61b8eb246ac3a5151abeb08 314 SMART SM00836 187 314 3.7E-14 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_06960 819003a8a61b8eb246ac3a5151abeb08 314 SUPERFAMILY SSF47323 182 314 2.35E-16 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_06960 819003a8a61b8eb246ac3a5151abeb08 314 SUPERFAMILY SSF55190 42 106 9.81E-7 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_06960 819003a8a61b8eb246ac3a5151abeb08 314 Gene3D G3DSA:3.30.1360.70 4 110 1.6E-6 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_06960 819003a8a61b8eb246ac3a5151abeb08 314 Gene3D G3DSA:1.10.730.10 182 314 3.4E-24 T 12-10-2018 UA74_06960 819003a8a61b8eb246ac3a5151abeb08 314 SMART SM01016 4 95 2.7E-9 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_06960 819003a8a61b8eb246ac3a5151abeb08 314 Gene3D G3DSA:3.40.50.620 137 181 3.4E-24 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_06960 819003a8a61b8eb246ac3a5151abeb08 314 Pfam PF05746 DALR anticodon binding domain 187 314 1.9E-16 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_04180 cb74aa45ab7ff9a7ed2dd321e40f69dc 341 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 28 311 37.299 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 UA74_04180 cb74aa45ab7ff9a7ed2dd321e40f69dc 341 Pfam PF02401 LytB protein 30 307 1.4E-90 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 UA74_04180 cb74aa45ab7ff9a7ed2dd321e40f69dc 341 Gene3D G3DSA:3.40.1010.20 124 220 2.3E-110 T 12-10-2018 UA74_04180 cb74aa45ab7ff9a7ed2dd321e40f69dc 341 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 30 308 4.2E-98 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 UA74_04180 cb74aa45ab7ff9a7ed2dd321e40f69dc 341 Gene3D G3DSA:3.40.50.11270 39 123 2.3E-110 T 12-10-2018 UA74_04180 cb74aa45ab7ff9a7ed2dd321e40f69dc 341 Gene3D G3DSA:3.40.1010.20 33 307 2.3E-110 T 12-10-2018 UA74_12280 ca14687659b5371012f61c19bf6724f2 181 SUPERFAMILY SSF56420 3 166 3.4E-50 T 12-10-2018 IPR036821 Peptide deformylase superfamily UA74_12280 ca14687659b5371012f61c19bf6724f2 181 Hamap MF_00163 Peptide deformylase [def]. 2 160 26.868 T 12-10-2018 IPR023635 Peptide deformylase UA74_12280 ca14687659b5371012f61c19bf6724f2 181 PIRSF PIRSF004749 1 170 3.0E-43 T 12-10-2018 IPR023635 Peptide deformylase UA74_12280 ca14687659b5371012f61c19bf6724f2 181 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 7 154 8.0E-36 T 12-10-2018 IPR023635 Peptide deformylase UA74_12280 ca14687659b5371012f61c19bf6724f2 181 PRINTS PR01576 Peptide deformylase signature 87 98 2.3E-30 T 12-10-2018 IPR023635 Peptide deformylase UA74_12280 ca14687659b5371012f61c19bf6724f2 181 PRINTS PR01576 Peptide deformylase signature 118 147 2.3E-30 T 12-10-2018 IPR023635 Peptide deformylase UA74_12280 ca14687659b5371012f61c19bf6724f2 181 PRINTS PR01576 Peptide deformylase signature 33 62 2.3E-30 T 12-10-2018 IPR023635 Peptide deformylase UA74_12280 ca14687659b5371012f61c19bf6724f2 181 PRINTS PR01576 Peptide deformylase signature 99 117 2.3E-30 T 12-10-2018 IPR023635 Peptide deformylase UA74_12280 ca14687659b5371012f61c19bf6724f2 181 Pfam PF01327 Polypeptide deformylase 4 148 1.5E-41 T 12-10-2018 IPR023635 Peptide deformylase UA74_12280 ca14687659b5371012f61c19bf6724f2 181 Gene3D G3DSA:3.90.45.10 1 176 1.6E-50 T 12-10-2018 IPR036821 Peptide deformylase superfamily UA74_22585 0d5b372c05ad2be4bf1696f2d4ab53d1 290 Gene3D G3DSA:1.10.260.40 6 82 2.1E-10 T 12-10-2018 UA74_22585 0d5b372c05ad2be4bf1696f2d4ab53d1 290 Pfam PF01381 Helix-turn-helix 15 64 4.0E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_22585 0d5b372c05ad2be4bf1696f2d4ab53d1 290 SUPERFAMILY SSF47413 8 66 3.75E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_22585 0d5b372c05ad2be4bf1696f2d4ab53d1 290 SMART SM00530 14 69 1.5E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_03725 08ea6140f64e1d7604564253deb6d95e 125 Gene3D G3DSA:1.25.40.10 9 62 1.9E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03725 08ea6140f64e1d7604564253deb6d95e 125 SMART SM00028 74 107 21.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03725 08ea6140f64e1d7604564253deb6d95e 125 SMART SM00028 40 73 0.13 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03725 08ea6140f64e1d7604564253deb6d95e 125 Gene3D G3DSA:1.25.40.10 63 123 2.0E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03725 08ea6140f64e1d7604564253deb6d95e 125 Pfam PF13432 Tetratricopeptide repeat 55 105 2.6E-8 T 12-10-2018 UA74_03725 08ea6140f64e1d7604564253deb6d95e 125 Pfam PF13432 Tetratricopeptide repeat 11 52 0.0065 T 12-10-2018 UA74_03725 08ea6140f64e1d7604564253deb6d95e 125 SUPERFAMILY SSF48452 8 106 7.59E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.6E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.6E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 Pfam PF00106 short chain dehydrogenase 3 200 7.5E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 SUPERFAMILY SSF51735 3 233 4.08E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 Gene3D G3DSA:3.40.50.720 2 235 4.5E-74 T 12-10-2018 UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24310 79fa9df77cf50ef20267d24f1ec0a956 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10745 74ec824a6da565cd11775ad0eafc4b7f 187 Gene3D G3DSA:1.10.1660.10 74 113 1.3E-5 T 12-10-2018 UA74_06190 8109d0dd54dd860f46a61fb82f864697 213 SUPERFAMILY SSF48498 100 201 1.28E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_06190 8109d0dd54dd860f46a61fb82f864697 213 SUPERFAMILY SSF46689 32 100 5.64E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_06190 8109d0dd54dd860f46a61fb82f864697 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 4.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06190 8109d0dd54dd860f46a61fb82f864697 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 4.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06190 8109d0dd54dd860f46a61fb82f864697 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 78 3.6E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06190 8109d0dd54dd860f46a61fb82f864697 213 Gene3D G3DSA:1.10.357.10 26 211 3.5E-56 T 12-10-2018 UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 Pfam PF00664 ABC transporter transmembrane region 170 431 3.1E-28 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 SMART SM00382 506 696 9.3E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 Gene3D G3DSA:3.40.50.300 471 717 1.8E-80 T 12-10-2018 UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 Pfam PF03412 Peptidase C39 family 11 138 4.0E-33 T 12-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 Gene3D G3DSA:1.20.1560.10 154 467 1.6E-61 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 SUPERFAMILY SSF90123 152 465 1.7E-54 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 ProSitePatterns PS00211 ABC transporters family signature. 618 632 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 SUPERFAMILY SSF52540 473 714 1.33E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 Gene3D G3DSA:3.90.70.10 2 145 1.7E-34 T 12-10-2018 UA74_09435 30e79a118c12a3fd7a641e28caebcba2 717 Pfam PF00005 ABC transporter 497 646 9.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_10395 363a32e011be9341891a3f4fdef5f72b 307 Gene3D G3DSA:3.90.550.10 9 222 2.8E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_10395 363a32e011be9341891a3f4fdef5f72b 307 SUPERFAMILY SSF53448 15 244 2.53E-37 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_10395 363a32e011be9341891a3f4fdef5f72b 307 Pfam PF00535 Glycosyl transferase family 2 20 177 2.3E-19 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 Gene3D G3DSA:2.40.10.10 99 285 1.6E-60 T 12-10-2018 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 139 144 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 SUPERFAMILY SSF50494 94 307 1.85E-31 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 Gene3D G3DSA:2.40.10.10 113 213 1.6E-60 T 12-10-2018 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 Pfam PF13365 Trypsin-like peptidase domain 128 281 3.2E-10 T 12-10-2018 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 ProSitePatterns PS00673 Serine proteases, V8 family, serine active site. 262 272 - T 12-10-2018 IPR000126 Serine proteases, V8 family, serine active site GO:0006508|GO:0008236 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 PRINTS PR00839 V8 serine protease family signature 128 145 2.5E-27 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 PRINTS PR00839 V8 serine protease family signature 223 236 2.5E-27 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 PRINTS PR00839 V8 serine protease family signature 162 174 2.5E-27 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 PRINTS PR00839 V8 serine protease family signature 273 285 2.5E-27 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 PRINTS PR00839 V8 serine protease family signature 256 272 2.5E-27 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_01145 f126ab9090f5da1579e03dbcd98c4962 310 PRINTS PR00839 V8 serine protease family signature 103 120 2.5E-27 T 12-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UA74_17815 060941b64417fb0e0227906db56897d3 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 5.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17815 060941b64417fb0e0227906db56897d3 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 5.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17815 060941b64417fb0e0227906db56897d3 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17815 060941b64417fb0e0227906db56897d3 298 Pfam PF00106 short chain dehydrogenase 3 117 5.8E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17815 060941b64417fb0e0227906db56897d3 298 Gene3D G3DSA:3.40.50.720 1 296 5.7E-41 T 12-10-2018 UA74_17815 060941b64417fb0e0227906db56897d3 298 SUPERFAMILY SSF51735 1 214 6.78E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17465 d890b0997b4614626e719813be2bab17 387 SUPERFAMILY SSF53383 5 376 6.78E-85 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_17465 d890b0997b4614626e719813be2bab17 387 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 374 7.7E-90 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_17465 d890b0997b4614626e719813be2bab17 387 Gene3D G3DSA:3.90.1150.10 259 384 4.6E-28 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_17465 d890b0997b4614626e719813be2bab17 387 PIRSF PIRSF000390 1 380 1.6E-88 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_17465 d890b0997b4614626e719813be2bab17 387 Gene3D G3DSA:3.40.640.10 1 258 1.3E-74 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_07955 6b4a82c0dd9ec436e0286cf5aa39450e 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UA74_07955 6b4a82c0dd9ec436e0286cf5aa39450e 476 Pfam PF00171 Aldehyde dehydrogenase family 23 474 1.0E-157 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_07955 6b4a82c0dd9ec436e0286cf5aa39450e 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 UA74_07955 6b4a82c0dd9ec436e0286cf5aa39450e 476 Gene3D G3DSA:3.40.309.10 256 447 2.2E-165 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_07955 6b4a82c0dd9ec436e0286cf5aa39450e 476 Gene3D G3DSA:3.40.605.10 22 472 2.2E-165 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_07955 6b4a82c0dd9ec436e0286cf5aa39450e 476 SUPERFAMILY SSF53720 7 474 1.7E-154 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_26465 c62d4f3dece081f4aaaebb0133576fad 440 Gene3D G3DSA:3.65.10.10 24 243 6.2E-141 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UA74_26465 c62d4f3dece081f4aaaebb0133576fad 440 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 12 425 29.129 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_26465 c62d4f3dece081f4aaaebb0133576fad 440 PIRSF PIRSF000505 4 427 1.8E-113 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_26465 c62d4f3dece081f4aaaebb0133576fad 440 ProSitePatterns PS00104 EPSP synthase signature 1. 92 106 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_26465 c62d4f3dece081f4aaaebb0133576fad 440 Gene3D G3DSA:3.65.10.10 16 415 6.2E-141 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UA74_26465 c62d4f3dece081f4aaaebb0133576fad 440 SUPERFAMILY SSF55205 12 421 1.13E-104 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 UA74_26465 c62d4f3dece081f4aaaebb0133576fad 440 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 18 422 2.9E-112 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_26465 c62d4f3dece081f4aaaebb0133576fad 440 ProSitePatterns PS00885 EPSP synthase signature 2. 338 356 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UA74_26465 c62d4f3dece081f4aaaebb0133576fad 440 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 416 9.8E-113 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 UA74_25255 6b43d1ee4cc28a0c20d801cdc69b76d7 397 SUPERFAMILY SSF53098 6 130 4.68E-31 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_25255 6b43d1ee4cc28a0c20d801cdc69b76d7 397 SMART SM00855 194 352 1.3E-19 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_25255 6b43d1ee4cc28a0c20d801cdc69b76d7 397 Pfam PF13456 Reverse transcriptase-like 10 132 1.4E-25 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 UA74_25255 6b43d1ee4cc28a0c20d801cdc69b76d7 397 SUPERFAMILY SSF53254 192 396 1.96E-53 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_25255 6b43d1ee4cc28a0c20d801cdc69b76d7 397 PIRSF PIRSF036922 2 397 1.6E-165 T 12-10-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing UA74_25255 6b43d1ee4cc28a0c20d801cdc69b76d7 397 Gene3D G3DSA:3.40.50.1240 193 397 3.5E-55 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_25255 6b43d1ee4cc28a0c20d801cdc69b76d7 397 Gene3D G3DSA:3.30.420.10 4 141 1.8E-41 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_25255 6b43d1ee4cc28a0c20d801cdc69b76d7 397 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 195 391 3.1E-57 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 SUPERFAMILY SSF52540 252 541 4.66E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 SUPERFAMILY SSF46894 3 88 9.92E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 Gene3D G3DSA:1.10.10.10 1 90 4.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 SUPERFAMILY SSF48452 809 974 8.93E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 Pfam PF03704 Bacterial transcriptional activator domain 95 237 1.3E-37 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 Gene3D G3DSA:1.25.40.10 92 254 1.1E-47 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 Pfam PF00931 NB-ARC domain 269 404 1.5E-9 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 SUPERFAMILY SSF48452 92 261 5.44E-33 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 PRINTS PR00364 Disease resistance protein signature 364 378 1.1E-7 T 12-10-2018 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 PRINTS PR00364 Disease resistance protein signature 475 489 1.1E-7 T 12-10-2018 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 PRINTS PR00364 Disease resistance protein signature 287 302 1.1E-7 T 12-10-2018 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 87 8.9E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 SMART SM01043 95 237 9.0E-50 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 Gene3D G3DSA:3.40.50.300 255 410 3.1E-21 T 12-10-2018 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 SMART SM00862 16 88 1.5E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_19455 7a6f1d00b4686b0686e9161bcd41d358 1056 Gene3D G3DSA:1.25.40.10 776 1006 1.0E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 SUPERFAMILY SSF48264 19 409 1.83E-94 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 Pfam PF00067 Cytochrome P450 214 379 2.9E-30 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 Gene3D G3DSA:1.10.630.10 23 409 1.5E-117 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00359 B-class P450 signature 163 178 1.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00359 B-class P450 signature 281 292 1.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00359 B-class P450 signature 327 342 1.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00359 B-class P450 signature 358 369 1.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00359 B-class P450 signature 200 222 1.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00359 B-class P450 signature 99 110 1.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00359 B-class P450 signature 146 162 1.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00359 B-class P450 signature 299 326 1.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00359 B-class P450 signature 349 358 1.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00385 P450 superfamily signature 246 263 1.1E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00385 P450 superfamily signature 281 292 1.1E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00385 P450 superfamily signature 349 358 1.1E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 PRINTS PR00385 P450 superfamily signature 358 369 1.1E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17450 bc62d712db14c70e8729dd768b1c1093 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 SUPERFAMILY SSF53850 92 292 2.53E-30 T 12-10-2018 UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Pfam PF03466 LysR substrate binding domain 91 293 6.4E-35 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Gene3D G3DSA:3.40.190.10 92 291 2.1E-49 T 12-10-2018 UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Gene3D G3DSA:1.10.10.10 2 88 3.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 SUPERFAMILY SSF46785 6 88 1.14E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 3.3E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_22640 ea31b5ffc9aacffda0a0b57b97ae9a53 296 Gene3D G3DSA:3.40.190.10 166 273 2.1E-49 T 12-10-2018 UA74_02075 bf028dcb5851203b70312883890cae69 390 SUPERFAMILY SSF56235 107 265 5.48E-12 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_02075 bf028dcb5851203b70312883890cae69 390 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 157 363 8.3E-14 T 12-10-2018 IPR005079 Peptidase C45 UA74_02075 bf028dcb5851203b70312883890cae69 390 Gene3D G3DSA:3.60.60.10 107 360 4.0E-24 T 12-10-2018 UA74_20675 51cc2af39db8fd352bce3816ec6ad632 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 220 5.1E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_20675 51cc2af39db8fd352bce3816ec6ad632 223 Gene3D G3DSA:3.40.50.2300 1 125 1.6E-36 T 12-10-2018 UA74_20675 51cc2af39db8fd352bce3816ec6ad632 223 Pfam PF00072 Response regulator receiver domain 5 112 4.2E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_20675 51cc2af39db8fd352bce3816ec6ad632 223 SMART SM00862 144 220 4.2E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_20675 51cc2af39db8fd352bce3816ec6ad632 223 SUPERFAMILY SSF52172 3 179 5.57E-41 T 12-10-2018 IPR011006 CheY-like superfamily UA74_20675 51cc2af39db8fd352bce3816ec6ad632 223 Gene3D G3DSA:1.10.10.10 126 223 1.6E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20675 51cc2af39db8fd352bce3816ec6ad632 223 SMART SM00448 2 112 7.6E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_15720 a8cf870c8c7779e2aa7ebef7415146d6 154 Gene3D G3DSA:1.10.10.10 4 147 5.3E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_15720 a8cf870c8c7779e2aa7ebef7415146d6 154 SUPERFAMILY SSF46785 14 145 3.33E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_08315 24a00a003b43aa899052427ad7ad4adb 362 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 15 357 2.3E-149 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 UA74_08315 24a00a003b43aa899052427ad7ad4adb 362 SUPERFAMILY SSF51569 15 356 2.41E-131 T 12-10-2018 UA74_08315 24a00a003b43aa899052427ad7ad4adb 362 Gene3D G3DSA:3.20.20.70 10 358 7.7E-154 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_08315 24a00a003b43aa899052427ad7ad4adb 362 PIRSF PIRSF001361 1 360 3.1E-156 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 UA74_08315 24a00a003b43aa899052427ad7ad4adb 362 Pfam PF00793 DAHP synthetase I family 51 345 1.5E-93 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 UA74_17185 cdb75afaadfb9ee81ec73284806496b3 347 Gene3D G3DSA:3.40.50.1980 31 169 7.7E-35 T 12-10-2018 UA74_17185 cdb75afaadfb9ee81ec73284806496b3 347 Pfam PF01497 Periplasmic binding protein 75 296 1.9E-15 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_17185 cdb75afaadfb9ee81ec73284806496b3 347 SUPERFAMILY SSF53807 41 344 7.06E-31 T 12-10-2018 UA74_17185 cdb75afaadfb9ee81ec73284806496b3 347 Gene3D G3DSA:3.40.50.1980 176 345 6.2E-26 T 12-10-2018 UA74_23830 da93d474b188a8aede57e94ce6113674 657 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 17 363 1.3E-105 T 12-10-2018 IPR016624 Uncharacterised conserved protein UCP014753 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 343 352 4.4E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 146 162 4.4E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 294 321 4.4E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 163 178 4.4E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 277 288 4.4E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 99 110 4.4E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 322 337 4.4E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 200 222 4.4E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00359 B-class P450 signature 352 363 4.4E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 SUPERFAMILY SSF48264 16 403 1.7E-93 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 Pfam PF00067 Cytochrome P450 224 373 2.8E-21 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 Gene3D G3DSA:1.10.630.10 13 407 6.9E-122 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00385 P450 superfamily signature 343 352 1.1E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00385 P450 superfamily signature 352 363 1.1E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00385 P450 superfamily signature 277 288 1.1E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_30050 95bfa53ea2c6b2ebfeebb8b6d424f610 408 PRINTS PR00385 P450 superfamily signature 242 259 1.1E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 PIRSF PIRSF006337 1 576 1.3E-221 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 SUPERFAMILY SSF51445 77 505 7.68E-105 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 Gene3D G3DSA:2.60.40.10 3 86 1.8E-25 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 Gene3D G3DSA:3.20.20.80 90 499 1.4E-161 T 12-10-2018 UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 6 543 1.5E-224 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 Pfam PF00128 Alpha amylase, catalytic domain 115 196 4.1E-12 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 6 57 8.9E-6 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 Gene3D G3DSA:1.10.10.760 431 471 1.4E-161 T 12-10-2018 UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 Pfam PF11941 Domain of unknown function (DUF3459) 491 580 9.7E-16 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 SMART SM00642 102 459 1.3E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_21250 8733d9d2c715a341b24fb10cb6b47c09 588 SUPERFAMILY SSF81296 6 81 1.22E-18 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_27055 8da203790e16d4d5ba0e5de5c54b7bc5 327 Pfam PF01026 TatD related DNase 4 228 3.4E-15 T 12-10-2018 IPR001130 TatD family GO:0016788 UA74_27055 8da203790e16d4d5ba0e5de5c54b7bc5 327 SUPERFAMILY SSF51556 2 256 1.93E-54 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_27055 8da203790e16d4d5ba0e5de5c54b7bc5 327 Gene3D G3DSA:3.20.20.140 2 262 1.9E-51 T 12-10-2018 UA74_08685 eb8c648c969c6b58a4777bd83a81f717 133 Gene3D G3DSA:3.30.2130.10 1 133 3.9E-43 T 12-10-2018 UA74_08685 eb8c648c969c6b58a4777bd83a81f717 133 SUPERFAMILY SSF55021 1 55 3.02E-9 T 12-10-2018 UA74_08685 eb8c648c969c6b58a4777bd83a81f717 133 SUPERFAMILY SSF55021 66 130 6.54E-17 T 12-10-2018 UA74_08685 eb8c648c969c6b58a4777bd83a81f717 133 Pfam PF13840 ACT domain 64 125 3.6E-18 T 12-10-2018 IPR027795 CASTOR, ACT domain UA74_08685 eb8c648c969c6b58a4777bd83a81f717 133 PIRSF PIRSF008459 1 133 2.5E-26 T 12-10-2018 IPR016540 Uncharacterised conserved protein UCP008459 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 64 75 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 Gene3D G3DSA:3.30.1490.20 112 185 2.4E-54 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 Pfam PF07478 D-ala D-ala ligase C-terminus 106 309 5.5E-44 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 Gene3D G3DSA:3.30.470.20 87 308 2.4E-54 T 12-10-2018 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 Gene3D G3DSA:3.40.50.20 2 85 2.0E-22 T 12-10-2018 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 Pfam PF01820 D-ala D-ala ligase N-terminus 6 86 3.1E-13 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 SUPERFAMILY SSF52440 6 97 1.25E-21 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 PIRSF PIRSF039102 38 315 1.3E-64 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 PIRSF PIRSF039102 2 49 2.0E-6 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 312 27.947 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_30275 fdef1a315fd7a72ce349ffd686496395 315 SUPERFAMILY SSF56059 97 308 8.93E-45 T 12-10-2018 UA74_07175 85fbdb88e27fb25b3c110328d7ea7238 261 SUPERFAMILY SSF53474 6 256 7.49E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07175 85fbdb88e27fb25b3c110328d7ea7238 261 Pfam PF00561 alpha/beta hydrolase fold 10 243 4.9E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_07175 85fbdb88e27fb25b3c110328d7ea7238 261 Gene3D G3DSA:3.40.50.1820 2 258 8.1E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07175 85fbdb88e27fb25b3c110328d7ea7238 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 5.4E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_07175 85fbdb88e27fb25b3c110328d7ea7238 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 34 49 5.4E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_07175 85fbdb88e27fb25b3c110328d7ea7238 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 5.4E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_07175 85fbdb88e27fb25b3c110328d7ea7238 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 5.4E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19110 375d8731c43744ad1f19cb37d64b86a9 991 SUPERFAMILY SSF52540 88 313 2.8E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19110 375d8731c43744ad1f19cb37d64b86a9 991 SUPERFAMILY SSF52540 252 621 6.3E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19110 375d8731c43744ad1f19cb37d64b86a9 991 SMART SM00490 498 582 2.6E-5 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_19110 375d8731c43744ad1f19cb37d64b86a9 991 SMART SM00487 126 327 6.7E-12 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_19110 375d8731c43744ad1f19cb37d64b86a9 991 Gene3D G3DSA:3.40.50.300 494 610 1.4E-6 T 12-10-2018 UA74_19110 375d8731c43744ad1f19cb37d64b86a9 991 Gene3D G3DSA:3.40.50.10810 128 456 1.9E-52 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily UA74_19110 375d8731c43744ad1f19cb37d64b86a9 991 Pfam PF00271 Helicase conserved C-terminal domain 462 582 8.5E-11 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_19110 375d8731c43744ad1f19cb37d64b86a9 991 Pfam PF00176 SNF2 family N-terminal domain 142 315 8.1E-9 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 UA74_05870 bc221f67f44ea0580660394957696d28 723 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 406 412 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_05870 bc221f67f44ea0580660394957696d28 723 Gene3D G3DSA:3.40.50.1000 385 653 1.3E-89 T 12-10-2018 IPR023214 HAD superfamily UA74_05870 bc221f67f44ea0580660394957696d28 723 Gene3D G3DSA:2.70.150.20 198 310 3.8E-35 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 Gene3D G3DSA:3.40.1110.10 415 535 1.3E-89 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00943 Copper-transporting ATPase signature 676 690 3.6E-8 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00943 Copper-transporting ATPase signature 580 597 3.6E-8 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00943 Copper-transporting ATPase signature 126 145 3.6E-8 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00943 Copper-transporting ATPase signature 328 342 3.6E-8 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00943 Copper-transporting ATPase signature 194 212 3.6E-8 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00943 Copper-transporting ATPase signature 387 402 3.6E-8 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 SUPERFAMILY SSF56784 403 708 8.25E-59 T 12-10-2018 IPR036412 HAD-like superfamily UA74_05870 bc221f67f44ea0580660394957696d28 723 SUPERFAMILY SSF81653 213 305 4.32E-24 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 UA74_05870 bc221f67f44ea0580660394957696d28 723 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 177 681 2.4E-83 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_05870 bc221f67f44ea0580660394957696d28 723 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 141 710 4.0E-171 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_05870 bc221f67f44ea0580660394957696d28 723 SUPERFAMILY SSF81665 142 397 1.7E-10 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UA74_05870 bc221f67f44ea0580660394957696d28 723 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 123 712 7.0E-167 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 Pfam PF00702 haloacid dehalogenase-like hydrolase 400 617 7.9E-47 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 626 638 7.9E-29 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 404 418 7.9E-29 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 550 560 7.9E-29 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 603 622 7.9E-29 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 255 269 7.9E-29 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 539 7.9E-29 T 12-10-2018 UA74_05870 bc221f67f44ea0580660394957696d28 723 Pfam PF00122 E1-E2 ATPase 205 383 4.0E-45 T 12-10-2018 UA74_02310 685b77e84a0bf509908b3ad3e05816d2 229 Gene3D G3DSA:2.30.180.10 71 229 6.1E-40 T 12-10-2018 IPR036378 FAS1 domain superfamily UA74_02310 685b77e84a0bf509908b3ad3e05816d2 229 Pfam PF02469 Fasciclin domain 107 227 1.4E-27 T 12-10-2018 IPR000782 FAS1 domain UA74_02310 685b77e84a0bf509908b3ad3e05816d2 229 SMART SM00554 131 228 1.3E-27 T 12-10-2018 IPR000782 FAS1 domain UA74_02310 685b77e84a0bf509908b3ad3e05816d2 229 SUPERFAMILY SSF82153 93 228 9.68E-30 T 12-10-2018 IPR036378 FAS1 domain superfamily UA74_06480 8bf13dd8dbdb922281acced30f68d83d 298 Gene3D G3DSA:3.40.47.10 22 214 1.7E-8 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_06480 8bf13dd8dbdb922281acced30f68d83d 298 SUPERFAMILY SSF53901 31 195 7.2E-8 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 Gene3D G3DSA:3.30.360.10 116 224 2.1E-80 T 12-10-2018 UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 11 115 3.4E-23 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 52 254 4.2E-53 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 SUPERFAMILY SSF55347 116 226 3.71E-37 T 12-10-2018 UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 SUPERFAMILY SSF51735 9 142 2.04E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 PIRSF PIRSF000161 9 256 1.1E-60 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 118 242 6.3E-29 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 11 255 28.609 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 Gene3D G3DSA:3.40.50.720 13 244 2.1E-80 T 12-10-2018 UA74_09410 0820927c6979c56d7a31255ddde6bdba 256 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 137 154 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.30.70.3290 2903 3325 1.5E-152 T 12-10-2018 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00825 Beta-ketoacyl synthase 9 417 1.4E-188 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00825 Beta-ketoacyl synthase 986 1412 2.7E-221 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00825 Beta-ketoacyl synthase 2461 2887 7.0E-211 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2393 2408 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:1.10.1200.10 888 965 1.3E-16 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM01294 2367 2434 1.4E-5 T 12-10-2018 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF47336 2361 2473 3.01E-20 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF53901 4 408 6.11E-86 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF51735 1878 2075 6.69E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF52151 524 813 2.62E-65 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2717 2834 1.1E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 247 365 1.3E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1242 1359 4.8E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2837 2941 1.5E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 367 487 5.3E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1362 1479 3.9E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF08659 KR domain 3555 3731 1.9E-56 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF08659 KR domain 2086 2264 3.0E-53 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF55048 1630 1706 1.02E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF47336 3831 3911 3.27E-16 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:1.10.1200.10 3822 3913 4.9E-29 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.40.47.10 980 1422 9.1E-185 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.40.47.10 2 425 6.7E-177 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.30.70.3290 440 875 5.4E-147 T 12-10-2018 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF51735 3550 3791 4.12E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF52151 2977 3269 6.02E-67 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1147 1163 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF51735 2084 2317 1.84E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 527 827 4.2E-97 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1509 1819 8.0E-112 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2981 3282 6.1E-116 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.40.366.10 525 830 5.4E-147 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.40.366.10 1507 1822 2.2E-151 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF52151 1505 1803 1.83E-67 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF51735 3338 3542 2.36E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.40.47.10 2456 2892 2.0E-181 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:1.10.1200.10 2346 2438 4.2E-33 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.40.366.10 2979 3285 1.5E-152 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF55048 653 712 2.49E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 984 1234 1.3E-85 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2459 2709 8.2E-86 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 239 4.8E-78 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2086 2266 1.0E-38 T 12-10-2018 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3555 3733 4.8E-44 T 12-10-2018 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF53901 983 1358 2.58E-99 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF00698 Acyl transferase domain 2981 3287 2.5E-83 T 12-10-2018 IPR014043 Acyl transferase UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF00698 Acyl transferase domain 525 845 4.8E-78 T 12-10-2018 IPR014043 Acyl transferase UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF00698 Acyl transferase domain 1508 1822 3.1E-79 T 12-10-2018 IPR014043 Acyl transferase UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF47336 898 998 2.49E-16 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF53901 2456 2825 7.29E-100 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2622 2638 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF00550 Phosphopantetheine attachment site 902 961 5.2E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF00550 Phosphopantetheine attachment site 2375 2434 5.0E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Pfam PF00550 Phosphopantetheine attachment site 3847 3906 4.2E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.40.50.720 3326 3805 1.3E-155 T 12-10-2018 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.40.50.720 1864 2337 4.9E-137 T 12-10-2018 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00823 Phosphopantetheine attachment site 2366 2438 2.8E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00823 Phosphopantetheine attachment site 895 965 5.8E-17 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SMART SM00823 Phosphopantetheine attachment site 3839 3911 3.7E-25 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 Gene3D G3DSA:3.30.70.3290 1428 1863 2.2E-151 T 12-10-2018 UA74_16525 40500e38d5ee8a5dc2ad108467449219 3994 SUPERFAMILY SSF55048 3102 3172 2.49E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 113 138 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 SUPERFAMILY SSF103473 5 445 4.84E-65 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 Gene3D G3DSA:1.20.1250.20 15 452 6.1E-105 T 12-10-2018 UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 25 35 2.1E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 108 127 2.1E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 373 385 2.1E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 350 371 2.1E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 PRINTS PR00171 Sugar transporter signature 260 270 2.1E-17 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 Pfam PF00083 Sugar (and other) transporter 18 449 3.2E-91 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 17 445 1.5E-85 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_19845 6bae871df8fd8ab9eccc467ec4a5289e 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 305 321 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_22635 6b553d829bad0be5ebee8173605453ed 306 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 6 303 5.0E-120 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 UA74_22635 6b553d829bad0be5ebee8173605453ed 306 Gene3D G3DSA:3.20.20.70 4 305 2.9E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_22635 6b553d829bad0be5ebee8173605453ed 306 SMART SM01130 13 304 1.6E-65 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_22635 6b553d829bad0be5ebee8173605453ed 306 Pfam PF00701 Dihydrodipicolinate synthetase family 15 301 3.3E-47 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_22635 6b553d829bad0be5ebee8173605453ed 306 PIRSF PIRSF001365 12 306 3.8E-55 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_22635 6b553d829bad0be5ebee8173605453ed 306 SUPERFAMILY SSF51569 15 301 6.49E-65 T 12-10-2018 UA74_22635 6b553d829bad0be5ebee8173605453ed 306 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 13 304 42.249 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 UA74_21955 8df8ae43f35250092b5a1246c12ef3dc 304 Pfam PF00440 Bacterial regulatory proteins, tetR family 77 123 2.9E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_21955 8df8ae43f35250092b5a1246c12ef3dc 304 SUPERFAMILY SSF46689 72 134 2.64E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_21955 8df8ae43f35250092b5a1246c12ef3dc 304 Gene3D G3DSA:1.10.10.60 69 131 8.7E-26 T 12-10-2018 UA74_21955 8df8ae43f35250092b5a1246c12ef3dc 304 SUPERFAMILY SSF48498 152 297 2.0E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_21955 8df8ae43f35250092b5a1246c12ef3dc 304 Gene3D G3DSA:1.10.357.10 147 302 2.8E-30 T 12-10-2018 UA74_21955 8df8ae43f35250092b5a1246c12ef3dc 304 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 150 293 1.4E-12 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_28920 1f6f9125d0709c5c1a590526d023d26d 313 SUPERFAMILY SSF51735 8 298 4.25E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_28920 1f6f9125d0709c5c1a590526d023d26d 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 216 8.2E-13 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_28920 1f6f9125d0709c5c1a590526d023d26d 313 Gene3D G3DSA:3.40.50.720 8 301 1.2E-37 T 12-10-2018 UA74_23215 33c4e3171dab2031005554cfe2066b58 380 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 28 377 30.711 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 UA74_23215 33c4e3171dab2031005554cfe2066b58 380 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 32 376 4.0E-130 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 UA74_23215 33c4e3171dab2031005554cfe2066b58 380 Pfam PF00561 alpha/beta hydrolase fold 61 364 1.6E-29 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_23215 33c4e3171dab2031005554cfe2066b58 380 Gene3D G3DSA:3.40.50.1820 37 370 6.9E-127 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23215 33c4e3171dab2031005554cfe2066b58 380 Gene3D G3DSA:1.10.1740.110 196 300 6.9E-127 T 12-10-2018 UA74_23215 33c4e3171dab2031005554cfe2066b58 380 PIRSF PIRSF000443 25 379 5.7E-123 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 UA74_23215 33c4e3171dab2031005554cfe2066b58 380 SUPERFAMILY SSF53474 34 377 1.46E-95 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20425 2b1b367264e42579101053163095e9cf 66 SMART SM00357 3 66 6.9E-29 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 UA74_20425 2b1b367264e42579101053163095e9cf 66 PRINTS PR00050 Cold shock protein signature 4 19 1.1E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_20425 2b1b367264e42579101053163095e9cf 66 PRINTS PR00050 Cold shock protein signature 39 57 1.1E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_20425 2b1b367264e42579101053163095e9cf 66 PRINTS PR00050 Cold shock protein signature 24 33 1.1E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_20425 2b1b367264e42579101053163095e9cf 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site UA74_20425 2b1b367264e42579101053163095e9cf 66 PIRSF PIRSF002599 1 66 1.2E-23 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 UA74_20425 2b1b367264e42579101053163095e9cf 66 Gene3D G3DSA:2.40.50.140 1 65 2.7E-31 T 12-10-2018 UA74_20425 2b1b367264e42579101053163095e9cf 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 7.8E-30 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_20425 2b1b367264e42579101053163095e9cf 66 SUPERFAMILY SSF50249 1 65 1.59E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_23815 815edb9d1b1df67ec1a3a828a6ca79d6 329 SMART SM00710 232 254 1300.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_23815 815edb9d1b1df67ec1a3a828a6ca79d6 329 SMART SM00710 154 176 1400.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_23815 815edb9d1b1df67ec1a3a828a6ca79d6 329 SMART SM00710 130 152 40.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_23815 815edb9d1b1df67ec1a3a828a6ca79d6 329 Gene3D G3DSA:2.160.20.10 49 329 3.4E-89 T 12-10-2018 IPR012334 Pectin lyase fold UA74_23815 815edb9d1b1df67ec1a3a828a6ca79d6 329 Pfam PF00544 Pectate lyase 106 265 2.4E-32 T 12-10-2018 IPR002022 Pectate lyase UA74_23815 815edb9d1b1df67ec1a3a828a6ca79d6 329 SMART SM00656 67 271 3.3E-37 T 12-10-2018 IPR002022 Pectate lyase UA74_23815 815edb9d1b1df67ec1a3a828a6ca79d6 329 SUPERFAMILY SSF51126 52 328 2.48E-70 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor UA74_12300 f0999ba4b0d0249a55f6040055bfa593 232 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UA74_12300 f0999ba4b0d0249a55f6040055bfa593 232 Gene3D G3DSA:3.20.20.70 1 223 1.4E-75 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_12300 f0999ba4b0d0249a55f6040055bfa593 232 PIRSF PIRSF001461 1 226 1.2E-86 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UA74_12300 f0999ba4b0d0249a55f6040055bfa593 232 SUPERFAMILY SSF51366 2 216 5.23E-60 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UA74_12300 f0999ba4b0d0249a55f6040055bfa593 232 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 1 215 9.0E-80 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UA74_12300 f0999ba4b0d0249a55f6040055bfa593 232 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UA74_12300 f0999ba4b0d0249a55f6040055bfa593 232 Pfam PF00834 Ribulose-phosphate 3 epimerase family 2 202 2.1E-75 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UA74_03765 a7f93a5fa30f9643f74a50ff6cdec099 247 SMART SM00987 55 233 8.1E-30 T 12-10-2018 UA74_03765 a7f93a5fa30f9643f74a50ff6cdec099 247 SMART SM00986 55 233 8.1E-30 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_03765 a7f93a5fa30f9643f74a50ff6cdec099 247 SUPERFAMILY SSF52141 23 236 3.27E-40 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_03765 a7f93a5fa30f9643f74a50ff6cdec099 247 Gene3D G3DSA:3.40.470.10 12 242 8.6E-63 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_03765 a7f93a5fa30f9643f74a50ff6cdec099 247 Pfam PF03167 Uracil DNA glycosylase superfamily 55 233 7.9E-26 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_17260 ab881d05e6e007b6b5569c9ad51c24dc 423 SUPERFAMILY SSF53756 20 416 3.14E-70 T 12-10-2018 UA74_17260 ab881d05e6e007b6b5569c9ad51c24dc 423 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 252 386 9.4E-16 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 UA74_17260 ab881d05e6e007b6b5569c9ad51c24dc 423 Gene3D G3DSA:3.40.50.2000 26 413 1.9E-126 T 12-10-2018 UA74_17260 ab881d05e6e007b6b5569c9ad51c24dc 423 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 26 416 3.4E-109 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 UA74_17260 ab881d05e6e007b6b5569c9ad51c24dc 423 Gene3D G3DSA:3.40.50.2000 241 400 1.9E-126 T 12-10-2018 UA74_08970 c4a0e9268a26b69303d20eed0625210e 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 368 65.835 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 UA74_08970 c4a0e9268a26b69303d20eed0625210e 368 SMART SM00729 117 342 0.0064 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_08970 c4a0e9268a26b69303d20eed0625210e 368 SUPERFAMILY SSF102114 115 339 2.09E-19 T 12-10-2018 UA74_08970 c4a0e9268a26b69303d20eed0625210e 368 Gene3D G3DSA:1.10.150.530 18 75 1.6E-8 T 12-10-2018 UA74_08970 c4a0e9268a26b69303d20eed0625210e 368 Pfam PF04055 Radical SAM superfamily 122 295 2.2E-24 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_08970 c4a0e9268a26b69303d20eed0625210e 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 366 7.7E-98 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 UA74_08970 c4a0e9268a26b69303d20eed0625210e 368 PIRSF PIRSF006004 13 368 1.5E-119 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 UA74_08970 c4a0e9268a26b69303d20eed0625210e 368 Gene3D G3DSA:3.20.20.70 81 355 1.7E-95 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_04770 8bfaacd7fd6a7909ec61b57880bacf22 1158 Pfam PF13361 UvrD-like helicase C-terminal domain 712 799 1.7E-9 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_04770 8bfaacd7fd6a7909ec61b57880bacf22 1158 Gene3D G3DSA:3.40.50.300 41 327 6.2E-45 T 12-10-2018 UA74_04770 8bfaacd7fd6a7909ec61b57880bacf22 1158 Gene3D G3DSA:3.40.50.300 677 827 1.7E-19 T 12-10-2018 UA74_04770 8bfaacd7fd6a7909ec61b57880bacf22 1158 SUPERFAMILY SSF52540 41 817 3.29E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04770 8bfaacd7fd6a7909ec61b57880bacf22 1158 Pfam PF00580 UvrD/REP helicase N-terminal domain 43 331 2.2E-35 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UA74_04770 8bfaacd7fd6a7909ec61b57880bacf22 1158 Pfam PF12705 PD-(D/E)XK nuclease superfamily 900 1148 4.3E-36 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type UA74_04770 8bfaacd7fd6a7909ec61b57880bacf22 1158 Gene3D G3DSA:1.10.10.160 144 250 6.2E-45 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily UA74_04770 8bfaacd7fd6a7909ec61b57880bacf22 1158 Gene3D G3DSA:3.40.50.300 465 562 2.6E-8 T 12-10-2018 UA74_07115 f913551ed09c2948d40815f1430a6281 271 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 19 268 1.2E-111 T 12-10-2018 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein UA74_07115 f913551ed09c2948d40815f1430a6281 271 Gene3D G3DSA:3.40.50.300 16 271 1.9E-81 T 12-10-2018 UA74_07115 f913551ed09c2948d40815f1430a6281 271 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_07115 f913551ed09c2948d40815f1430a6281 271 Pfam PF00005 ABC transporter 34 192 5.5E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_07115 f913551ed09c2948d40815f1430a6281 271 SMART SM00382 43 241 8.5E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_07115 f913551ed09c2948d40815f1430a6281 271 PIRSF PIRSF039085 15 269 4.7E-98 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UA74_07115 f913551ed09c2948d40815f1430a6281 271 SUPERFAMILY SSF52540 19 263 1.85E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25610 d0b4f18a1b6b81e2a074ee51e8a1be1d 143 Pfam PF00545 ribonuclease 59 137 2.7E-27 T 12-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 UA74_25610 d0b4f18a1b6b81e2a074ee51e8a1be1d 143 Gene3D G3DSA:3.10.450.30 47 143 4.8E-36 T 12-10-2018 UA74_25610 d0b4f18a1b6b81e2a074ee51e8a1be1d 143 SUPERFAMILY SSF53933 50 140 7.37E-35 T 12-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 UA74_21740 cdc961eb928cb9d5209b26bf02195605 236 Gene3D G3DSA:3.30.420.10 1 150 1.9E-55 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_21740 cdc961eb928cb9d5209b26bf02195605 236 SUPERFAMILY SSF53098 1 139 1.77E-52 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_21740 cdc961eb928cb9d5209b26bf02195605 236 Hamap MF_00042 Ribonuclease H [rnhA]. 1 147 31.104 T 12-10-2018 IPR022892 Ribonuclease HI GO:0004523 UA74_21740 cdc961eb928cb9d5209b26bf02195605 236 Pfam PF00075 RNase H 1 138 8.1E-49 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 UA74_28045 811945f28b83c9de99df8b29e1f2d1ba 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 3.2E-17 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like UA74_28045 811945f28b83c9de99df8b29e1f2d1ba 96 Gene3D G3DSA:1.10.287.1060 1 96 8.2E-22 T 12-10-2018 UA74_28045 811945f28b83c9de99df8b29e1f2d1ba 96 Pfam PF06013 Proteins of 100 residues with WXG 5 88 5.3E-13 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like UA74_28045 811945f28b83c9de99df8b29e1f2d1ba 96 SUPERFAMILY SSF140453 4 95 7.85E-20 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_16545 70415935a63c13db2addf9229e01f945 288 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 191 287 2.1E-31 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UA74_16545 70415935a63c13db2addf9229e01f945 288 SUPERFAMILY SSF48179 191 288 1.87E-31 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_16545 70415935a63c13db2addf9229e01f945 288 PIRSF PIRSF000105 1 288 1.2E-76 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 UA74_16545 70415935a63c13db2addf9229e01f945 288 Gene3D G3DSA:3.40.50.720 1 193 4.1E-52 T 12-10-2018 UA74_16545 70415935a63c13db2addf9229e01f945 288 SUPERFAMILY SSF51735 4 186 3.29E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16545 70415935a63c13db2addf9229e01f945 288 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 186 3.0E-50 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UA74_16545 70415935a63c13db2addf9229e01f945 288 Gene3D G3DSA:1.10.1040.10 194 288 1.0E-32 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_13340 8f873641ca470ab43615308153cd81b1 344 SUPERFAMILY SSF48008 97 226 5.49E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_13340 8f873641ca470ab43615308153cd81b1 344 Pfam PF07729 FCD domain 100 220 2.6E-21 T 12-10-2018 IPR011711 GntR, C-terminal UA74_13340 8f873641ca470ab43615308153cd81b1 344 SMART SM00345 13 71 7.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_13340 8f873641ca470ab43615308153cd81b1 344 Gene3D G3DSA:1.10.10.10 9 72 3.4E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13340 8f873641ca470ab43615308153cd81b1 344 Gene3D G3DSA:1.20.120.530 96 224 2.9E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_13340 8f873641ca470ab43615308153cd81b1 344 SUPERFAMILY SSF46785 13 75 9.62E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_13340 8f873641ca470ab43615308153cd81b1 344 SMART SM00895 100 221 2.1E-20 T 12-10-2018 IPR011711 GntR, C-terminal UA74_13340 8f873641ca470ab43615308153cd81b1 344 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 71 1.4E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_01675 f42f95a8eff0c333b53e85d04f639a0b 266 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 102 109 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UA74_01675 f42f95a8eff0c333b53e85d04f639a0b 266 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 235 1.6E-62 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UA74_01675 f42f95a8eff0c333b53e85d04f639a0b 266 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 235 39.257 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UA74_01675 f42f95a8eff0c333b53e85d04f639a0b 266 Gene3D G3DSA:3.90.550.10 1 241 9.7E-69 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_01675 f42f95a8eff0c333b53e85d04f639a0b 266 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 236 1.0E-61 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UA74_01675 f42f95a8eff0c333b53e85d04f639a0b 266 SUPERFAMILY SSF53448 3 235 4.77E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_13360 11fec5dbdd2c0feef4482371609c7a12 220 Gene3D G3DSA:1.10.357.10 56 200 9.9E-31 T 12-10-2018 UA74_13360 11fec5dbdd2c0feef4482371609c7a12 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13360 11fec5dbdd2c0feef4482371609c7a12 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13360 11fec5dbdd2c0feef4482371609c7a12 220 Gene3D G3DSA:1.10.10.60 5 54 3.1E-24 T 12-10-2018 UA74_13360 11fec5dbdd2c0feef4482371609c7a12 220 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_13360 11fec5dbdd2c0feef4482371609c7a12 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 4.1E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13360 11fec5dbdd2c0feef4482371609c7a12 220 SUPERFAMILY SSF46689 5 78 7.28E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 ProSitePatterns PS00012 Phosphopantetheine attachment site. 574 589 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.40.50.12780 1101 1504 1.6E-116 T 12-10-2018 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF52777 843 1101 2.89E-47 T 12-10-2018 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1137 1533 8.8E-112 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 61 465 2.8E-132 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.30.559.30 838 1093 3.3E-120 T 12-10-2018 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.30.300.30 1505 1604 1.7E-20 T 12-10-2018 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF53474 1693 1918 1.28E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF47336 544 612 2.22E-14 T 12-10-2018 IPR036736 ACP-like superfamily UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF56801 1076 1625 1.57E-130 T 12-10-2018 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1254 1265 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 SMART SM00823 Phosphopantetheine attachment site 1617 1688 0.0015 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 SMART SM00823 Phosphopantetheine attachment site 550 618 0.018 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.30.300.30 435 539 2.3E-29 T 12-10-2018 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.40.50.1820 1696 1921 4.6E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00975 Thioesterase domain 1708 1807 1.4E-21 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF56801 9 562 4.84E-152 T 12-10-2018 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.40.50.12780 30 433 3.2E-136 T 12-10-2018 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF47336 1610 1684 1.96E-15 T 12-10-2018 IPR036736 ACP-like superfamily UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:3.30.559.10 659 1028 3.3E-120 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 527 3.2E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00501 AMP-binding enzyme 1117 1510 4.1E-79 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00501 AMP-binding enzyme 41 441 1.2E-98 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00550 Phosphopantetheine attachment site 1619 1683 4.2E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00550 Phosphopantetheine attachment site 552 612 4.6E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Pfam PF00668 Condensation domain 655 1096 2.5E-86 T 12-10-2018 IPR001242 Condensation domain UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 SUPERFAMILY SSF52777 659 836 3.89E-45 T 12-10-2018 UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:1.10.1200.10 540 620 1.1E-20 T 12-10-2018 IPR036736 ACP-like superfamily UA74_14820 12de093eb5df77a1abc0ec692220b924 1922 Gene3D G3DSA:1.10.1200.10 1605 1686 3.3E-21 T 12-10-2018 IPR036736 ACP-like superfamily UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 PIRSF PIRSF001365 10 304 3.5E-73 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 SMART SM01130 12 299 6.9E-111 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 140 157 1.9E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 47 68 1.9E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 115 131 1.9E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 83 101 1.9E-28 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 16 292 5.7E-79 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 SUPERFAMILY SSF51569 12 300 5.97E-86 T 12-10-2018 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 Pfam PF00701 Dihydrodipicolinate synthetase family 13 293 2.5E-73 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 Gene3D G3DSA:3.20.20.70 7 302 4.9E-102 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 145 175 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 50 67 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_09490 0fd412ba575fa272be1f22ab1147834a 318 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 12 297 53.025 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_06935 e37a3b95c7990bf792dff6782f586695 310 Pfam PF08281 Sigma-70, region 4 108 159 2.5E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_06935 e37a3b95c7990bf792dff6782f586695 310 SUPERFAMILY SSF88659 84 164 6.35E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_06935 e37a3b95c7990bf792dff6782f586695 310 Gene3D G3DSA:3.10.450.50 173 295 1.8E-9 T 12-10-2018 UA74_06935 e37a3b95c7990bf792dff6782f586695 310 SUPERFAMILY SSF88946 5 88 5.49E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_06935 e37a3b95c7990bf792dff6782f586695 310 Gene3D G3DSA:1.10.10.10 90 164 2.9E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_06935 e37a3b95c7990bf792dff6782f586695 310 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 163 8.1E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_06935 e37a3b95c7990bf792dff6782f586695 310 Gene3D G3DSA:1.10.1740.10 2 87 1.1E-10 T 12-10-2018 UA74_06935 e37a3b95c7990bf792dff6782f586695 310 Pfam PF04542 Sigma-70 region 2 8 73 2.6E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_06935 e37a3b95c7990bf792dff6782f586695 310 SUPERFAMILY SSF54427 172 291 5.12E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_29060 9b9aebb4a4ec976082d979c455aaa2fa 383 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 16 337 7.1E-118 T 12-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 UA74_29060 9b9aebb4a4ec976082d979c455aaa2fa 383 Gene3D G3DSA:3.20.20.70 20 263 1.3E-80 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_29060 9b9aebb4a4ec976082d979c455aaa2fa 383 Pfam PF01207 Dihydrouridine synthase (Dus) 26 329 6.0E-106 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 UA74_29060 9b9aebb4a4ec976082d979c455aaa2fa 383 Gene3D G3DSA:1.10.1200.80 271 335 3.3E-8 T 12-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 UA74_29060 9b9aebb4a4ec976082d979c455aaa2fa 383 PIRSF PIRSF006621 14 347 3.9E-112 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 UA74_29060 9b9aebb4a4ec976082d979c455aaa2fa 383 SUPERFAMILY SSF51395 23 334 3.11E-85 T 12-10-2018 UA74_29060 9b9aebb4a4ec976082d979c455aaa2fa 383 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 108 126 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 249 262 3.1E-45 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 288 302 3.1E-45 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 129 144 3.1E-45 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 186 199 3.1E-45 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 264 284 3.1E-45 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 217 227 3.1E-45 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 58 77 3.1E-45 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 PRINTS PR00733 Glycosyl hydrolase family 6 signature 101 114 3.1E-45 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 Gene3D G3DSA:3.20.20.40 36 322 1.9E-109 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 PIRSF PIRSF001100 2 325 7.5E-87 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 SUPERFAMILY SSF51989 38 321 8.76E-89 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 106 122 - T 12-10-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 UA74_12160 8f15bcd4378381213ef6dd7dc0efc176 326 Pfam PF01341 Glycosyl hydrolases family 6 48 304 1.0E-65 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_08080 396bede087feb5c2bf38018ba9188cff 426 Gene3D G3DSA:1.10.8.60 316 424 8.6E-39 T 12-10-2018 UA74_08080 396bede087feb5c2bf38018ba9188cff 426 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UA74_08080 396bede087feb5c2bf38018ba9188cff 426 Gene3D G3DSA:3.30.50.30 3 50 5.5E-24 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily UA74_08080 396bede087feb5c2bf38018ba9188cff 426 Gene3D G3DSA:3.40.50.300 54 314 1.7E-106 T 12-10-2018 UA74_08080 396bede087feb5c2bf38018ba9188cff 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 3.7E-16 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_08080 396bede087feb5c2bf38018ba9188cff 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 1.3E-194 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UA74_08080 396bede087feb5c2bf38018ba9188cff 426 SUPERFAMILY SSF57716 11 46 1.37E-11 T 12-10-2018 UA74_08080 396bede087feb5c2bf38018ba9188cff 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 310 1.5E-49 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_08080 396bede087feb5c2bf38018ba9188cff 426 SMART SM01086 317 411 4.5E-32 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_08080 396bede087feb5c2bf38018ba9188cff 426 SMART SM00994 10 49 1.1E-23 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UA74_08080 396bede087feb5c2bf38018ba9188cff 426 SUPERFAMILY SSF52540 59 405 6.35E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08080 396bede087feb5c2bf38018ba9188cff 426 SMART SM00382 113 266 4.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_08080 396bede087feb5c2bf38018ba9188cff 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.266 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 266 285 1.8E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 188 200 1.8E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 355 363 1.8E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 PRINTS PR00410 Phenol hydroxylase reductase family signature 291 300 1.8E-13 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 Pfam PF00175 Oxidoreductase NAD-binding domain 267 368 2.1E-14 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 Gene3D G3DSA:2.40.30.10 157 253 4.5E-20 T 12-10-2018 UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 Pfam PF00042 Globin 26 118 1.2E-9 T 12-10-2018 IPR000971 Globin GO:0020037 UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 SUPERFAMILY SSF52343 259 388 2.1E-28 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 SUPERFAMILY SSF63380 160 255 2.33E-22 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 Gene3D G3DSA:3.40.50.80 256 389 2.3E-26 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 Gene3D G3DSA:1.10.490.10 22 156 5.2E-36 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 SUPERFAMILY SSF46458 24 151 6.39E-33 T 12-10-2018 IPR009050 Globin-like superfamily UA74_29570 e65d54f0397238651bd6b8cf886a7eb5 390 Pfam PF00970 Oxidoreductase FAD-binding domain 163 255 3.9E-14 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 UA74_08905 f7c938048fffc4903df7b9812ce43e20 128 Gene3D G3DSA:3.40.1350.10 21 127 5.0E-27 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 UA74_08905 f7c938048fffc4903df7b9812ce43e20 128 SUPERFAMILY SSF52980 20 115 2.41E-19 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_08905 f7c938048fffc4903df7b9812ce43e20 128 Pfam PF02021 Uncharacterised protein family UPF0102 21 111 9.3E-27 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 UA74_08905 f7c938048fffc4903df7b9812ce43e20 128 Hamap MF_00048 UPF0102 protein YraN [yraN]. 14 124 20.741 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 UA74_29545 f71f4b363f99164534e53a2b166881ba 690 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 314 328 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_29545 f71f4b363f99164534e53a2b166881ba 690 Gene3D G3DSA:3.30.420.40 161 342 9.7E-93 T 12-10-2018 UA74_29545 f71f4b363f99164534e53a2b166881ba 690 SUPERFAMILY SSF53067 4 155 9.54E-25 T 12-10-2018 UA74_29545 f71f4b363f99164534e53a2b166881ba 690 SUPERFAMILY SSF53067 169 353 1.3E-30 T 12-10-2018 UA74_29545 f71f4b363f99164534e53a2b166881ba 690 Pfam PF00012 Hsp70 protein 88 352 6.8E-30 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29545 f71f4b363f99164534e53a2b166881ba 690 Gene3D G3DSA:3.90.640.10 206 292 9.7E-93 T 12-10-2018 UA74_29545 f71f4b363f99164534e53a2b166881ba 690 Gene3D G3DSA:3.30.420.40 4 352 9.7E-93 T 12-10-2018 UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 283 445 5.8E-34 T 12-10-2018 IPR000160 GGDEF domain UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 SUPERFAMILY SSF55073 291 449 2.94E-41 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 SUPERFAMILY SSF55785 147 273 8.05E-27 T 12-10-2018 IPR035965 PAS domain superfamily UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 Gene3D G3DSA:3.30.70.270 280 459 9.6E-51 T 12-10-2018 UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 Pfam PF08448 PAS fold 172 277 2.8E-14 T 12-10-2018 IPR013656 PAS fold-4 UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 SUPERFAMILY SSF141868 466 714 1.07E-81 T 12-10-2018 IPR035919 EAL domain superfamily UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 SMART SM00091 160 226 5.6E-10 T 12-10-2018 IPR000014 PAS domain UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 SMART SM00267 275 447 2.2E-52 T 12-10-2018 IPR000160 GGDEF domain UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 SMART SM00052 457 708 1.4E-113 T 12-10-2018 IPR001633 EAL domain UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 Pfam PF00563 EAL domain 466 703 6.8E-71 T 12-10-2018 IPR001633 EAL domain UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 Gene3D G3DSA:3.20.20.450 460 719 3.5E-97 T 12-10-2018 IPR035919 EAL domain superfamily UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 156 282 1.8E-26 T 12-10-2018 IPR000014 PAS domain UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 Pfam PF00990 Diguanylate cyclase, GGDEF domain 286 442 2.9E-39 T 12-10-2018 IPR000160 GGDEF domain UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 Gene3D G3DSA:3.30.450.20 146 273 4.4E-27 T 12-10-2018 UA74_29235 c967a01ae6a94f58aee49aeda03bcb07 719 SMART SM00086 233 275 3.8E-5 T 12-10-2018 IPR001610 PAC motif UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 Pfam PF08281 Sigma-70, region 4 114 165 6.1E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 166 2.1E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 SUPERFAMILY SSF54427 178 294 1.0E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 Pfam PF04542 Sigma-70 region 2 15 78 1.8E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 Gene3D G3DSA:1.10.10.10 96 170 2.5E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 Gene3D G3DSA:1.10.1740.10 10 91 2.2E-10 T 12-10-2018 UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 SUPERFAMILY SSF88659 88 166 1.33E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 SUPERFAMILY SSF88946 15 95 1.73E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 14 293 8.7E-110 T 12-10-2018 IPR014303 RNA polymerase sigma-70, ECF type UA74_09920 6ad89703ce35db92a80a46044e0ab86f 299 Gene3D G3DSA:3.10.450.50 174 292 2.8E-6 T 12-10-2018 UA74_21090 b43d834fd193360cb722a889d6986946 344 Gene3D G3DSA:1.10.260.40 6 69 2.4E-23 T 12-10-2018 UA74_21090 b43d834fd193360cb722a889d6986946 344 SUPERFAMILY SSF53822 86 344 1.58E-67 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_21090 b43d834fd193360cb722a889d6986946 344 Gene3D G3DSA:3.40.50.2300 87 336 9.9E-76 T 12-10-2018 UA74_21090 b43d834fd193360cb722a889d6986946 344 Gene3D G3DSA:3.40.50.2300 176 338 9.9E-76 T 12-10-2018 UA74_21090 b43d834fd193360cb722a889d6986946 344 Pfam PF13377 Periplasmic binding protein-like domain 185 344 3.5E-40 T 12-10-2018 UA74_21090 b43d834fd193360cb722a889d6986946 344 SMART SM00354 12 82 3.2E-23 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_21090 b43d834fd193360cb722a889d6986946 344 SUPERFAMILY SSF47413 12 69 3.07E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_21090 b43d834fd193360cb722a889d6986946 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 9.4E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 SUPERFAMILY SSF46894 161 230 2.24E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 ProSitePatterns PS00622 LuxR-type HTH domain signature. 184 211 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 Pfam PF00072 Response regulator receiver domain 4 126 3.8E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 SUPERFAMILY SSF52172 1 144 2.28E-29 T 12-10-2018 IPR011006 CheY-like superfamily UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 212 4.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 200 4.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 184 4.2E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 SMART SM00448 2 125 1.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 Gene3D G3DSA:3.40.50.12740 2 230 2.4E-65 T 12-10-2018 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 SMART SM00421 167 224 8.6E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_21500 d74a6440ccf831f415432f48bfe45b06 234 Pfam PF00196 Bacterial regulatory proteins, luxR family 169 223 8.0E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_19315 2613d955345e734fe03f0940e59771ad 145 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 142 3.4E-49 T 12-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 UA74_19315 2613d955345e734fe03f0940e59771ad 145 Pfam PF02566 OsmC-like protein 45 140 8.2E-16 T 12-10-2018 IPR003718 OsmC/Ohr family UA74_19315 2613d955345e734fe03f0940e59771ad 145 SUPERFAMILY SSF82784 1 136 6.41E-30 T 12-10-2018 IPR036102 OsmC/Ohr superfamily UA74_19315 2613d955345e734fe03f0940e59771ad 145 Gene3D G3DSA:3.30.300.20 3 144 4.3E-37 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_09480 d8924c756ec18a3062414ceb98777027 246 Gene3D G3DSA:2.70.70.10 93 241 6.1E-44 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_09480 d8924c756ec18a3062414ceb98777027 246 SUPERFAMILY SSF51261 104 238 2.25E-47 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_09480 d8924c756ec18a3062414ceb98777027 246 Pfam PF01551 Peptidase family M23 140 234 1.0E-30 T 12-10-2018 IPR016047 Peptidase M23 UA74_03870 d8924c756ec18a3062414ceb98777027 246 Gene3D G3DSA:2.70.70.10 93 241 6.1E-44 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_03870 d8924c756ec18a3062414ceb98777027 246 SUPERFAMILY SSF51261 104 238 2.25E-47 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_03870 d8924c756ec18a3062414ceb98777027 246 Pfam PF01551 Peptidase family M23 140 234 1.0E-30 T 12-10-2018 IPR016047 Peptidase M23 UA74_00360 11a4488ad63be5e986bb7cde897a7219 1255 Gene3D G3DSA:3.40.50.200 205 504 1.2E-94 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_00360 11a4488ad63be5e986bb7cde897a7219 1255 PRINTS PR00723 Subtilisin serine protease family (S8) signature 230 249 9.0E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_00360 11a4488ad63be5e986bb7cde897a7219 1255 PRINTS PR00723 Subtilisin serine protease family (S8) signature 268 281 9.0E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_00360 11a4488ad63be5e986bb7cde897a7219 1255 PRINTS PR00723 Subtilisin serine protease family (S8) signature 443 459 9.0E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_00360 11a4488ad63be5e986bb7cde897a7219 1255 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 444 454 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_00360 11a4488ad63be5e986bb7cde897a7219 1255 SUPERFAMILY SSF52743 211 502 1.27E-82 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_00360 11a4488ad63be5e986bb7cde897a7219 1255 Pfam PF00082 Subtilase family 230 493 1.0E-53 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_23145 b750172a31856da8793084f62255918d 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 3.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_23145 b750172a31856da8793084f62255918d 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 3.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_23145 b750172a31856da8793084f62255918d 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 65 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_23145 b750172a31856da8793084f62255918d 214 SUPERFAMILY SSF46689 11 89 1.02E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_23145 b750172a31856da8793084f62255918d 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 2.5E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_23145 b750172a31856da8793084f62255918d 214 Gene3D G3DSA:1.10.357.10 7 212 8.6E-48 T 12-10-2018 UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 Gene3D G3DSA:1.20.120.530 99 252 3.6E-31 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 SMART SM00895 118 243 6.1E-24 T 12-10-2018 IPR011711 GntR, C-terminal UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 SUPERFAMILY SSF48008 116 251 1.8E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 SMART SM00345 34 93 2.3E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 SUPERFAMILY SSF46785 26 95 2.11E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 Gene3D G3DSA:1.10.10.10 29 97 4.8E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 83 6.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 67 6.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 Pfam PF07729 FCD domain 118 242 5.7E-27 T 12-10-2018 IPR011711 GntR, C-terminal UA74_19960 ae67c860a7df1793ab88ffd06aa07b9a 274 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 92 1.2E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF52096 1295 1500 1.53E-21 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF02785 Biotin carboxylase C-terminal domain 340 449 1.2E-34 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF51230 581 656 1.7E-14 T 12-10-2018 IPR011053 Single hybrid motif UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF52440 2 118 6.14E-32 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF01039 Carboxyl transferase domain 1334 1822 1.5E-29 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF56059 88 332 5.05E-60 T 12-10-2018 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 115 3.4E-33 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:3.30.470.130 1 452 1.9E-170 T 12-10-2018 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF52096 1551 1824 5.68E-36 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 SUPERFAMILY SSF51246 335 450 1.36E-34 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:2.40.50.100 582 655 4.5E-14 T 12-10-2018 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 SMART SM00878 340 448 5.1E-48 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF00364 Biotin-requiring enzyme 591 653 3.8E-7 T 12-10-2018 IPR000089 Biotin/lipoyl attachment UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 328 1.3E-63 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Pfam PF08326 Acetyl-CoA carboxylase, central region 1016 1208 1.9E-14 T 12-10-2018 IPR013537 Acetyl-CoA carboxylase, central domain GO:0003989|GO:0005524|GO:0006633 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-163765|Reactome: R-HSA-196780|Reactome: R-HSA-200425|Reactome: R-HSA-2426168 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:3.90.226.10 1517 1826 2.7E-56 T 12-10-2018 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 Gene3D G3DSA:3.90.226.10 1261 1507 5.1E-36 T 12-10-2018 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 158 172 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_15370 f44462657e80db1de9c5a5e4799effe4 1826 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 292 299 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:3.90.226.10 902 1116 2.7E-63 T 12-10-2018 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF50156 788 865 3.1E-9 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:2.130.10.10 319 688 3.9E-98 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:2.30.42.10 786 870 1.8E-5 T 12-10-2018 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 Pfam PF14684 Tricorn protease C1 domain 710 774 2.3E-27 T 12-10-2018 IPR028204 Tricorn protease C1 domain UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF69304 373 673 5.62E-19 T 12-10-2018 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF52096 709 1106 3.64E-65 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 PIRSF PIRSF036421 1 1114 0.0 T 12-10-2018 IPR012393 Tricorn protease GO:0008236 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 Pfam PF14685 Tricorn protease PDZ domain 788 868 2.3E-26 T 12-10-2018 IPR029414 Tricorn protease, PDZ domain UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 SMART SM00245 888 1081 2.4E-16 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 Pfam PF03572 Peptidase family S41 924 1080 3.7E-21 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 SUPERFAMILY SSF69304 5 300 1.31E-28 T 12-10-2018 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:2.120.10.60 1 297 4.7E-85 T 12-10-2018 UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 Pfam PF07676 WD40-like Beta Propeller Repeat 45 64 6.4E-4 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_03705 666d1a3ae9952681b16a5d5a1b781ad7 1120 Gene3D G3DSA:3.30.750.44 708 776 2.8E-27 T 12-10-2018 UA74_16650 16a99cc3aca27158e0af25a4413123e5 287 Pfam PF00005 ABC transporter 23 161 1.3E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_16650 16a99cc3aca27158e0af25a4413123e5 287 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_16650 16a99cc3aca27158e0af25a4413123e5 287 Gene3D G3DSA:3.40.50.300 1 238 2.8E-60 T 12-10-2018 UA74_16650 16a99cc3aca27158e0af25a4413123e5 287 SUPERFAMILY SSF52540 3 221 7.14E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16650 16a99cc3aca27158e0af25a4413123e5 287 SMART SM00382 30 216 4.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_17690 e2c1905c3af6dbfcc79c58a8862bf214 324 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 17 285 8.3E-100 T 12-10-2018 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 UA74_17690 e2c1905c3af6dbfcc79c58a8862bf214 324 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 8 303 17.868 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_17690 e2c1905c3af6dbfcc79c58a8862bf214 324 Gene3D G3DSA:1.20.120.920 109 304 1.9E-68 T 12-10-2018 UA74_17690 e2c1905c3af6dbfcc79c58a8862bf214 324 Pfam PF01867 CRISPR associated protein Cas1 147 250 4.3E-11 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_17690 e2c1905c3af6dbfcc79c58a8862bf214 324 Gene3D G3DSA:3.100.10.20 15 108 1.9E-20 T 12-10-2018 UA74_17690 e2c1905c3af6dbfcc79c58a8862bf214 324 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 148 254 1.9E-22 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_19580 0118395fb8a37fe50e92b0a105b51e8c 119 SUPERFAMILY SSF54593 4 115 6.06E-13 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_19580 0118395fb8a37fe50e92b0a105b51e8c 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 113 1.7E-4 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_19580 0118395fb8a37fe50e92b0a105b51e8c 119 Gene3D G3DSA:3.10.180.10 1 118 1.7E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_05115 173dfa83671cc78c57d55c7aaec3c5b4 277 SMART SM00967 39 115 1.1E-8 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UA74_05115 173dfa83671cc78c57d55c7aaec3c5b4 277 Pfam PF00588 SpoU rRNA Methylase family 126 266 4.2E-37 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_05115 173dfa83671cc78c57d55c7aaec3c5b4 277 SUPERFAMILY SSF75217 116 272 9.16E-44 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_05115 173dfa83671cc78c57d55c7aaec3c5b4 277 Gene3D G3DSA:3.40.1280.10 121 276 4.8E-49 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_05115 173dfa83671cc78c57d55c7aaec3c5b4 277 SUPERFAMILY SSF55315 11 110 2.9E-22 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_05115 173dfa83671cc78c57d55c7aaec3c5b4 277 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 40 110 1.3E-7 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UA74_05115 173dfa83671cc78c57d55c7aaec3c5b4 277 Gene3D G3DSA:3.30.1330.30 11 112 1.2E-24 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_18175 1429bb75dc11f0b29bb9e2b179a5dc57 64 Gene3D G3DSA:3.30.70.20 1 63 2.3E-18 T 12-10-2018 UA74_18175 1429bb75dc11f0b29bb9e2b179a5dc57 64 SUPERFAMILY SSF54862 2 62 3.45E-13 T 12-10-2018 UA74_18175 1429bb75dc11f0b29bb9e2b179a5dc57 64 Pfam PF13459 4Fe-4S single cluster domain 3 62 1.7E-11 T 12-10-2018 UA74_18175 1429bb75dc11f0b29bb9e2b179a5dc57 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.2E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_18175 1429bb75dc11f0b29bb9e2b179a5dc57 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.2E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_18175 1429bb75dc11f0b29bb9e2b179a5dc57 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.2E-5 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_25640 a14251c4dd2bca1da42e6ced4422f0e5 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.5E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_25640 a14251c4dd2bca1da42e6ced4422f0e5 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 2.5E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_25640 a14251c4dd2bca1da42e6ced4422f0e5 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 4.0E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_25640 a14251c4dd2bca1da42e6ced4422f0e5 221 SUPERFAMILY SSF48498 94 200 1.09E-16 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_25640 a14251c4dd2bca1da42e6ced4422f0e5 221 SUPERFAMILY SSF46689 20 98 1.31E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_25640 a14251c4dd2bca1da42e6ced4422f0e5 221 Gene3D G3DSA:1.10.357.10 12 205 2.2E-48 T 12-10-2018 UA74_21910 4a99e08cd0acebd732dcbca8a6c7dd00 174 Pfam PF05145 Transition state regulatory protein AbrB 5 159 9.1E-26 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 UA74_21910 4a99e08cd0acebd732dcbca8a6c7dd00 174 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 5 159 2.3E-30 T 12-10-2018 IPR017516 AbrB duplication UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 44 106 4.5E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 Gene3D G3DSA:1.20.120.530 110 247 2.0E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 SUPERFAMILY SSF48008 113 241 2.48E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 80 96 8.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 66 80 8.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 SUPERFAMILY SSF46785 42 110 1.88E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 Pfam PF07729 FCD domain 116 237 2.5E-25 T 12-10-2018 IPR011711 GntR, C-terminal UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 SMART SM00895 116 238 3.0E-21 T 12-10-2018 IPR011711 GntR, C-terminal UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 Gene3D G3DSA:1.10.10.10 40 107 4.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20115 379ba3395470fa3ac48b8bf8fc96bf8d 248 SMART SM00345 48 106 9.6E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 Gene3D G3DSA:1.10.510.10 98 275 1.7E-41 T 12-10-2018 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 Pfam PF00069 Protein kinase domain 12 263 6.7E-48 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 SUPERFAMILY SSF56112 4 268 3.64E-71 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 356 368 7.6E-9 T 12-10-2018 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 415 431 7.6E-9 T 12-10-2018 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 462 487 7.6E-9 T 12-10-2018 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 296 308 7.6E-9 T 12-10-2018 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 PRINTS PR01217 Proline rich extensin signature 438 455 7.6E-9 T 12-10-2018 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 Gene3D G3DSA:3.30.200.20 2 95 5.7E-29 T 12-10-2018 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 SMART SM00220 12 267 1.8E-59 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_20270 c1f3c91da6d09b2baaa8e7aced46e3ed 521 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF10385 RNA polymerase beta subunit external 1 domain 504 570 1.4E-24 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:3.90.1100.10 31 631 0.0 T 12-10-2018 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:2.40.270.10 29 1025 0.0 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:2.40.50.150 742 868 0.0 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 SUPERFAMILY SSF64484 25 1135 0.0 T 12-10-2018 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:2.40.50.100 632 706 0.0 T 12-10-2018 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 242 844 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF04565 RNA polymerase Rpb2, domain 3 426 494 2.0E-28 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF04563 RNA polymerase beta subunit 89 411 9.8E-22 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:3.90.1800.10 1034 1087 1.6E-10 T 12-10-2018 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 26 1125 12.252 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF04561 RNA polymerase Rpb2, domain 2 168 367 1.3E-25 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:3.90.1110.10 173 361 0.0 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Gene3D G3DSA:2.30.150.10 507 574 0.0 T 12-10-2018 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF00562 RNA polymerase Rpb2, domain 6 633 1047 1.4E-156 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 ProSitePatterns PS01166 RNA polymerases beta chain signature. 870 882 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02860 fc1a14b894268c792a851f2d4c43cb89 1164 Pfam PF04560 RNA polymerase Rpb2, domain 7 1049 1123 4.8E-26 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF49299 1054 1159 1.83E-14 T 12-10-2018 IPR035986 PKD domain superfamily UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF00801 PKD domain 1083 1148 1.4E-8 T 12-10-2018 IPR000601 PKD domain UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF00801 PKD domain 753 808 1.3E-10 T 12-10-2018 IPR000601 PKD domain UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SMART SM00089 1079 1160 1.6E-13 T 12-10-2018 IPR022409 PKD/Chitinase domain UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SMART SM00089 738 824 1.1E-13 T 12-10-2018 IPR022409 PKD/Chitinase domain UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF52317 45 271 1.03E-44 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF49785 933 1066 2.04E-17 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:2.60.40.10 1080 1160 2.6E-15 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF50952 279 711 1.12E-16 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:2.120.10.30 272 667 2.0E-71 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:2.60.120.260 929 1068 5.9E-25 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SMART SM00606 929 1068 3.7E-13 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF07995 Glucose / Sorbosone dehydrogenase 291 551 4.6E-30 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:3.40.50.880 32 271 1.7E-77 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Gene3D G3DSA:2.60.40.10 727 823 3.9E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF06283 Trehalose utilisation 48 264 1.8E-75 T 12-10-2018 IPR029010 ThuA-like domain UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 Pfam PF03422 Carbohydrate binding module (family 6) 946 1067 7.0E-13 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_13845 c69f0eafc74d2bd17cbeba1c581c3f36 1160 SUPERFAMILY SSF49299 736 823 3.14E-17 T 12-10-2018 IPR035986 PKD domain superfamily UA74_09020 6c44af178de164e378be0f218b38fad2 380 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 16 367 33.422 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UA74_09020 6c44af178de164e378be0f218b38fad2 380 SUPERFAMILY SSF56014 276 364 2.55E-12 T 12-10-2018 UA74_09020 6c44af178de164e378be0f218b38fad2 380 Gene3D G3DSA:3.20.20.20 13 271 8.2E-106 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_09020 6c44af178de164e378be0f218b38fad2 380 SUPERFAMILY SSF51717 28 219 1.65E-9 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_09020 6c44af178de164e378be0f218b38fad2 380 Pfam PF04551 GcpE protein 21 361 6.2E-135 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UA74_09020 6c44af178de164e378be0f218b38fad2 380 Gene3D G3DSA:3.30.413.10 272 372 1.0E-36 T 12-10-2018 UA74_09020 6c44af178de164e378be0f218b38fad2 380 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 18 360 6.8E-128 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UA74_09020 6c44af178de164e378be0f218b38fad2 380 PIRSF PIRSF004640 12 372 7.3E-146 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UA74_29915 3482c5e73bcd59de48cded3d77d4bdf2 413 SUPERFAMILY SSF52518 49 401 4.32E-95 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_29915 3482c5e73bcd59de48cded3d77d4bdf2 413 Gene3D G3DSA:3.40.50.970 21 399 1.2E-111 T 12-10-2018 UA74_29915 3482c5e73bcd59de48cded3d77d4bdf2 413 Pfam PF00676 Dehydrogenase E1 component 82 361 4.3E-70 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 UA74_29915 3482c5e73bcd59de48cded3d77d4bdf2 413 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 52 398 1.7E-126 T 12-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 UA74_07355 2db067010f9cc82bc6ce53468f29ea08 662 SUPERFAMILY SSF51445 14 386 8.84E-108 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07355 2db067010f9cc82bc6ce53468f29ea08 662 Gene3D G3DSA:3.20.20.80 2 389 2.4E-132 T 12-10-2018 UA74_07355 2db067010f9cc82bc6ce53468f29ea08 662 Pfam PF08532 Beta-galactosidase trimerisation domain 395 599 4.2E-61 T 12-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_07355 2db067010f9cc82bc6ce53468f29ea08 662 PIRSF PIRSF001084 5 661 7.1E-247 T 12-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_07355 2db067010f9cc82bc6ce53468f29ea08 662 Pfam PF08533 Beta-galactosidase C-terminal domain 609 657 4.5E-5 T 12-10-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_07355 2db067010f9cc82bc6ce53468f29ea08 662 Pfam PF02449 Beta-galactosidase 17 383 3.9E-142 T 12-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_07355 2db067010f9cc82bc6ce53468f29ea08 662 SUPERFAMILY SSF52317 392 599 5.8E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_07355 2db067010f9cc82bc6ce53468f29ea08 662 Gene3D G3DSA:3.40.50.880 392 602 2.6E-66 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_07355 2db067010f9cc82bc6ce53468f29ea08 662 Gene3D G3DSA:2.60.40.1180 607 660 4.9E-10 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_24905 b3301417889cb6c20a43f35e72fb5aa8 562 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 124 297 1.4E-60 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 UA74_24905 b3301417889cb6c20a43f35e72fb5aa8 562 Gene3D G3DSA:1.20.810.10 13 442 2.5E-92 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 UA74_24905 b3301417889cb6c20a43f35e72fb5aa8 562 SUPERFAMILY SSF81342 23 300 7.85E-62 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 UA74_10920 32877ccd882c649093b1a70088a68573 541 SUPERFAMILY SSF51905 6 374 2.44E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10920 32877ccd882c649093b1a70088a68573 541 Gene3D G3DSA:3.40.30.120 392 532 1.2E-44 T 12-10-2018 UA74_10920 32877ccd882c649093b1a70088a68573 541 Gene3D G3DSA:3.50.50.60 7 358 2.0E-111 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10920 32877ccd882c649093b1a70088a68573 541 Pfam PF01494 FAD binding domain 6 363 1.2E-103 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_10920 32877ccd882c649093b1a70088a68573 541 Gene3D G3DSA:3.30.9.50 72 295 2.0E-111 T 12-10-2018 UA74_10920 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.1E-46 T 12-10-2018 UA74_10920 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 182 1.1E-46 T 12-10-2018 UA74_10920 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 1.1E-46 T 12-10-2018 UA74_10920 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 349 365 1.1E-46 T 12-10-2018 UA74_10920 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 329 1.1E-46 T 12-10-2018 UA74_10920 32877ccd882c649093b1a70088a68573 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 349 1.1E-46 T 12-10-2018 UA74_06825 1aa6684c4d564684af82f0063a88286a 73 Pfam PF12277 Protein of unknown function (DUF3618) 2 47 3.5E-17 T 12-10-2018 IPR022062 Protein of unknown function DUF3618 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SUPERFAMILY SSF52540 274 546 5.34E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SUPERFAMILY SSF48452 734 843 8.06E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 Gene3D G3DSA:1.25.40.10 670 965 2.7E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SUPERFAMILY SSF48452 108 272 4.14E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 Gene3D G3DSA:1.10.10.10 1 104 6.6E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SUPERFAMILY SSF46894 4 56 7.94E-5 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 Gene3D G3DSA:3.40.50.300 277 438 9.1E-25 T 12-10-2018 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SMART SM00028 854 887 1.5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SMART SM00028 734 767 9.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SMART SM00028 934 967 170.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SMART SM00028 774 807 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SMART SM00028 814 847 270.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SMART SM00028 894 927 80.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 Gene3D G3DSA:1.25.40.10 108 270 5.5E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 Pfam PF13424 Tetratricopeptide repeat 734 806 4.8E-8 T 12-10-2018 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SUPERFAMILY SSF48452 814 954 1.19E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 SMART SM01043 109 253 3.5E-18 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 PRINTS PR00364 Disease resistance protein signature 482 496 5.3E-8 T 12-10-2018 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 PRINTS PR00364 Disease resistance protein signature 314 329 5.3E-8 T 12-10-2018 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 PRINTS PR00364 Disease resistance protein signature 394 408 5.3E-8 T 12-10-2018 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 Pfam PF00931 NB-ARC domain 309 548 2.2E-14 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_23055 0cdbe593c3cfb910e5b3d738c5f2889a 982 Pfam PF03704 Bacterial transcriptional activator domain 109 252 3.8E-19 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_17735 1ef2efec02844f903427004468ea8318 300 Pfam PF08281 Sigma-70, region 4 116 167 5.2E-6 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_17735 1ef2efec02844f903427004468ea8318 300 Pfam PF04542 Sigma-70 region 2 11 74 3.6E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_17735 1ef2efec02844f903427004468ea8318 300 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 169 2.4E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_17735 1ef2efec02844f903427004468ea8318 300 Gene3D G3DSA:1.10.10.10 100 175 1.5E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17735 1ef2efec02844f903427004468ea8318 300 SUPERFAMILY SSF54427 182 292 2.47E-10 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_17735 1ef2efec02844f903427004468ea8318 300 SUPERFAMILY SSF88946 6 87 1.77E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_17735 1ef2efec02844f903427004468ea8318 300 Gene3D G3DSA:3.10.450.50 179 296 2.2E-7 T 12-10-2018 UA74_17735 1ef2efec02844f903427004468ea8318 300 SUPERFAMILY SSF88659 109 170 6.54E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_17735 1ef2efec02844f903427004468ea8318 300 Gene3D G3DSA:1.10.1740.10 2 99 6.4E-11 T 12-10-2018 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 Gene3D G3DSA:3.40.50.300 29 270 3.1E-83 T 12-10-2018 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 SMART SM00382 60 231 6.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 Pfam PF00154 recA bacterial DNA recombination protein 10 271 2.7E-142 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 Gene3D G3DSA:3.30.250.10 271 347 1.7E-30 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 ProSitePatterns PS00321 recA signature. 216 224 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 Hamap MF_00268 Protein RecA [recA]. 8 332 52.706 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 300 317 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 130 159 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 96 125 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 246 275 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 213 241 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 PRINTS PR00142 RecA protein signature 168 197 1.1E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 SUPERFAMILY SSF54752 271 329 1.01E-20 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 7 327 2.2E-172 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UA74_08535 2afa91c9b5607319ddae74b44d58eb11 347 SUPERFAMILY SSF52540 7 270 1.62E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 SUPERFAMILY SSF57716 281 330 2.02E-14 T 12-10-2018 UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 Pfam PF06827 Zinc finger found in FPG and IleRS 302 330 8.9E-5 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 SMART SM01232 189 281 8.7E-41 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 SUPERFAMILY SSF46946 188 278 1.91E-25 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 Gene3D G3DSA:1.10.8.50 191 330 1.9E-41 T 12-10-2018 UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 330 39.6 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 SUPERFAMILY SSF81624 2 198 2.36E-33 T 12-10-2018 IPR035937 MutM-like, N-terminal UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 189 275 1.3E-21 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 SMART SM00898 2 170 1.5E-47 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 329 2.0E-81 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 UA74_25585 7fb6a418969eb812a1f74319dc4d230c 337 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 168 5.5E-34 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_15845 c993bb5ce51c2aaceabeb28abfe11f1a 376 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 60 113 5.0E-11 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_15845 c993bb5ce51c2aaceabeb28abfe11f1a 376 SUPERFAMILY SSF56349 59 351 7.65E-54 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_15845 c993bb5ce51c2aaceabeb28abfe11f1a 376 Gene3D G3DSA:1.10.443.10 162 356 1.9E-37 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_15845 c993bb5ce51c2aaceabeb28abfe11f1a 376 Pfam PF00589 Phage integrase family 167 343 6.1E-14 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_15845 c993bb5ce51c2aaceabeb28abfe11f1a 376 Gene3D G3DSA:1.10.150.130 56 160 4.0E-24 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_00340 d277e235f604049c20f51f6360b63b19 86 Gene3D G3DSA:3.30.2310.20 1 84 9.7E-41 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily UA74_00340 d277e235f604049c20f51f6360b63b19 86 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 2.0E-37 T 12-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 UA74_00340 d277e235f604049c20f51f6360b63b19 86 SUPERFAMILY SSF143011 1 83 1.44E-26 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily UA74_00340 d277e235f604049c20f51f6360b63b19 86 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 2.5E-32 T 12-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 371 155.947 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 SUPERFAMILY SSF52540 45 276 1.3E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 SMART SM00382 76 209 1.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 SUPERFAMILY SSF46785 281 355 9.25E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 Gene3D G3DSA:1.10.10.10 282 360 2.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 278 353 4.0E-30 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 Gene3D G3DSA:1.10.8.60 207 281 2.3E-30 T 12-10-2018 UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 31 260 4.1E-105 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 Gene3D G3DSA:3.40.50.300 45 206 3.3E-35 T 12-10-2018 UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 278 351 3.4E-28 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 UA74_11085 04e0d2bfd8a4f4214e57f52b11dcc1c7 371 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 49 351 2.2E-133 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 UA74_27990 18384d202d9519ee428fe3dd3d801d00 135 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 116 1.9E-16 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_27990 18384d202d9519ee428fe3dd3d801d00 135 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 122 1.5E-22 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UA74_27990 18384d202d9519ee428fe3dd3d801d00 135 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 122 21.156 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UA74_27990 18384d202d9519ee428fe3dd3d801d00 135 Gene3D G3DSA:3.90.470.20 1 122 5.2E-34 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_27990 18384d202d9519ee428fe3dd3d801d00 135 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 72 109 0.007 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UA74_27990 18384d202d9519ee428fe3dd3d801d00 135 SUPERFAMILY SSF56214 1 121 1.03E-25 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_27990 18384d202d9519ee428fe3dd3d801d00 135 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 121 7.0E-24 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Gene3D G3DSA:3.30.470.30 662 861 1.7E-77 T 12-10-2018 UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Pfam PF00149 Calcineurin-like phosphoesterase 182 387 3.5E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 476 798 6.2E-143 T 12-10-2018 IPR032380 Polynucleotide kinase-phosphatase, ligase domain UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Gene3D G3DSA:3.60.21.10 172 424 4.6E-70 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Pfam PF13671 AAA domain 11 140 8.3E-20 T 12-10-2018 UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 802 861 1.4E-31 T 12-10-2018 IPR032390 Polynucleotide kinase-phosphatase, C-terminal UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Gene3D G3DSA:3.30.470.30 446 639 1.9E-67 T 12-10-2018 UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 SUPERFAMILY SSF56300 180 406 2.66E-40 T 12-10-2018 UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 3 861 0.0 T 12-10-2018 IPR024028 Polynucleotide kinase-phosphatase, bacterial UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 SUPERFAMILY SSF56091 524 772 8.63E-11 T 12-10-2018 UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 Gene3D G3DSA:3.40.50.300 2 171 1.0E-43 T 12-10-2018 UA74_04040 d9ee15d1d43b6c486591ae46b3e3cf0c 861 SUPERFAMILY SSF52540 11 145 3.24E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_27115 35deca12481dccb26e7db744e5a71b0b 437 Gene3D G3DSA:3.90.25.10 287 421 1.4E-50 T 12-10-2018 UA74_27115 35deca12481dccb26e7db744e5a71b0b 437 SUPERFAMILY SSF51735 161 428 1.67E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_27115 35deca12481dccb26e7db744e5a71b0b 437 Gene3D G3DSA:3.40.50.720 164 420 1.4E-50 T 12-10-2018 UA74_27115 35deca12481dccb26e7db744e5a71b0b 437 Gene3D G3DSA:3.10.450.50 2 132 2.7E-37 T 12-10-2018 UA74_27115 35deca12481dccb26e7db744e5a71b0b 437 SUPERFAMILY SSF54427 5 128 7.19E-31 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_27115 35deca12481dccb26e7db744e5a71b0b 437 Pfam PF12680 SnoaL-like domain 11 118 8.4E-14 T 12-10-2018 IPR037401 SnoaL-like domain UA74_02285 506ad68ab35b8ca5b32e909718572b9a 301 Gene3D G3DSA:1.20.1440.100 61 137 2.3E-61 T 12-10-2018 UA74_02285 506ad68ab35b8ca5b32e909718572b9a 301 Gene3D G3DSA:3.40.50.1000 50 262 2.3E-61 T 12-10-2018 IPR023214 HAD superfamily UA74_02285 506ad68ab35b8ca5b32e909718572b9a 301 SUPERFAMILY SSF56784 49 266 1.31E-28 T 12-10-2018 IPR036412 HAD-like superfamily UA74_02285 506ad68ab35b8ca5b32e909718572b9a 301 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 49 249 3.0E-54 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like UA74_02285 506ad68ab35b8ca5b32e909718572b9a 301 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 49 237 4.4E-17 T 12-10-2018 UA74_02285 506ad68ab35b8ca5b32e909718572b9a 301 Pfam PF12710 haloacid dehalogenase-like hydrolase 50 236 6.0E-25 T 12-10-2018 UA74_16685 30bb14e59b71251bac756b4ffb29d0d3 150 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 131 9.4E-34 T 12-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 UA74_16685 30bb14e59b71251bac756b4ffb29d0d3 150 Gene3D G3DSA:3.40.930.10 2 145 2.7E-36 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UA74_16685 30bb14e59b71251bac756b4ffb29d0d3 150 SUPERFAMILY SSF55804 3 144 8.76E-32 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UA74_16685 30bb14e59b71251bac756b4ffb29d0d3 150 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 144 3.8E-30 T 12-10-2018 IPR002178 PTS EIIA type-2 domain UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Pfam PF07549 SecD/SecF GG Motif 497 520 4.1E-8 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Pfam PF07549 SecD/SecF GG Motif 27 48 5.7E-4 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 475 752 22.728 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 7 454 33.619 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Gene3D G3DSA:1.20.1640.10 451 499 2.5E-11 T 12-10-2018 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Gene3D G3DSA:1.20.1640.10 564 753 6.1E-8 T 12-10-2018 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 SUPERFAMILY SSF82866 581 747 4.71E-26 T 12-10-2018 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 SUPERFAMILY SSF82866 244 446 9.94E-34 T 12-10-2018 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Pfam PF02355 Protein export membrane protein 572 748 6.6E-49 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Pfam PF02355 Protein export membrane protein 268 437 3.3E-9 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Gene3D G3DSA:3.30.70.3400 58 267 4.2E-50 T 12-10-2018 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Gene3D G3DSA:3.30.1360.200 113 265 4.2E-50 T 12-10-2018 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 501 741 3.0E-53 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 PRINTS PR01755 Bacterial translocase SecF protein signature 657 675 1.3E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 PRINTS PR01755 Bacterial translocase SecF protein signature 500 515 1.3E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 PRINTS PR01755 Bacterial translocase SecF protein signature 689 704 1.3E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 PRINTS PR01755 Bacterial translocase SecF protein signature 609 623 1.3E-22 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 Gene3D G3DSA:1.20.1640.10 281 450 2.5E-11 T 12-10-2018 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 35 440 8.2E-107 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 UA74_12675 aab079af6feb1aa69a927e1a26e849d5 773 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 208 434 2.1E-58 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UA74_27485 2bcea2643e446c8cbb18aba8d7ef9ac5 570 Pfam PF00005 ABC transporter 285 441 1.0E-11 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_27485 2bcea2643e446c8cbb18aba8d7ef9ac5 570 SUPERFAMILY SSF52540 19 239 9.29E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_27485 2bcea2643e446c8cbb18aba8d7ef9ac5 570 SUPERFAMILY SSF52540 274 501 1.62E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_27485 2bcea2643e446c8cbb18aba8d7ef9ac5 570 Gene3D G3DSA:3.40.50.300 251 509 3.7E-34 T 12-10-2018 UA74_27485 2bcea2643e446c8cbb18aba8d7ef9ac5 570 SMART SM00382 43 228 6.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_27485 2bcea2643e446c8cbb18aba8d7ef9ac5 570 ProSitePatterns PS00211 ABC transporters family signature. 414 428 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_27485 2bcea2643e446c8cbb18aba8d7ef9ac5 570 Pfam PF00005 ABC transporter 36 180 5.1E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_27485 2bcea2643e446c8cbb18aba8d7ef9ac5 570 Gene3D G3DSA:3.40.50.300 10 250 1.1E-53 T 12-10-2018 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Pfam PF07724 AAA domain (Cdc48 subfamily) 568 738 2.7E-48 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 744 824 8.7E-22 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 125 172 3.2E-13 T 12-10-2018 IPR004176 Clp, N-terminal UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 60 99 0.017 T 12-10-2018 IPR004176 Clp, N-terminal UA74_11780 071210b5fb82977b513272c88ab06ddc 848 SMART SM00382 235 381 6.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_11780 071210b5fb82977b513272c88ab06ddc 848 SMART SM00382 569 745 1.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:1.10.8.60 744 838 8.3E-26 T 12-10-2018 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:1.10.8.60 382 513 2.3E-41 T 12-10-2018 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:1.10.1780.10 37 172 1.3E-25 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 331 343 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 240 357 2.8E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 SUPERFAMILY SSF52540 196 494 6.84E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11780 071210b5fb82977b513272c88ab06ddc 848 SUPERFAMILY SSF52540 518 824 2.16E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11780 071210b5fb82977b513272c88ab06ddc 848 SMART SM01086 744 833 1.0E-32 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_11780 071210b5fb82977b513272c88ab06ddc 848 SUPERFAMILY SSF81923 41 172 3.92E-16 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Pfam PF02151 UvrB/uvrC motif 455 487 1.1E-6 T 12-10-2018 IPR001943 UVR domain GO:0005515 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 603 621 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:3.40.50.300 187 379 4.9E-66 T 12-10-2018 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 573 591 5.1E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 680 694 5.1E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 618 636 5.1E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 647 665 5.1E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:3.40.50.300 521 742 2.0E-82 T 12-10-2018 UA74_11780 071210b5fb82977b513272c88ab06ddc 848 Gene3D G3DSA:4.10.860.10 445 499 2.3E-41 T 12-10-2018 UA74_24320 d770b239db96b9fba3d788908ca7af50 384 Gene3D G3DSA:3.40.50.1820 8 384 7.2E-133 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24320 d770b239db96b9fba3d788908ca7af50 384 Pfam PF06441 Epoxide hydrolase N terminus 8 113 3.6E-36 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 UA74_24320 d770b239db96b9fba3d788908ca7af50 384 PIRSF PIRSF001112 2 384 2.7E-121 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 UA74_24320 d770b239db96b9fba3d788908ca7af50 384 SUPERFAMILY SSF53474 4 380 1.5E-91 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24320 d770b239db96b9fba3d788908ca7af50 384 PRINTS PR00412 Epoxide hydrolase signature 133 148 4.0E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_24320 d770b239db96b9fba3d788908ca7af50 384 PRINTS PR00412 Epoxide hydrolase signature 179 192 4.0E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_24320 d770b239db96b9fba3d788908ca7af50 384 PRINTS PR00412 Epoxide hydrolase signature 104 122 4.0E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_24320 d770b239db96b9fba3d788908ca7af50 384 PRINTS PR00412 Epoxide hydrolase signature 355 377 4.0E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_13810 dd70143e566e36a8b3faa0b429db603c 630 Pfam PF00326 Prolyl oligopeptidase family 414 624 1.4E-31 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_13810 dd70143e566e36a8b3faa0b429db603c 630 Gene3D G3DSA:2.120.10.30 8 266 7.8E-13 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_13810 dd70143e566e36a8b3faa0b429db603c 630 Gene3D G3DSA:3.40.50.1820 341 629 5.6E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_13810 dd70143e566e36a8b3faa0b429db603c 630 SUPERFAMILY SSF53474 293 627 1.68E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_13810 dd70143e566e36a8b3faa0b429db603c 630 SUPERFAMILY SSF82171 21 353 1.7E-22 T 12-10-2018 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 204 4.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 SUPERFAMILY SSF52172 6 134 5.83E-32 T 12-10-2018 IPR011006 CheY-like superfamily UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 Pfam PF00072 Response regulator receiver domain 8 120 3.2E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 SMART SM00421 148 205 9.1E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 Gene3D G3DSA:3.40.50.12740 6 211 1.7E-64 T 12-10-2018 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 SMART SM00448 6 119 5.8E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03410 8e680ea5688b278171b23685a17f5fcf 218 SUPERFAMILY SSF46894 148 211 9.86E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_25650 d8dd774ea124f1fea0fdee1f5b9d49cb 422 SUPERFAMILY SSF81301 31 190 9.15E-48 T 12-10-2018 UA74_25650 d8dd774ea124f1fea0fdee1f5b9d49cb 422 SUPERFAMILY SSF53335 187 395 2.59E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_25650 d8dd774ea124f1fea0fdee1f5b9d49cb 422 Gene3D G3DSA:3.30.460.10 25 193 1.2E-48 T 12-10-2018 UA74_25650 d8dd774ea124f1fea0fdee1f5b9d49cb 422 Pfam PF08241 Methyltransferase domain 234 327 9.3E-22 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_25650 d8dd774ea124f1fea0fdee1f5b9d49cb 422 Pfam PF04229 GrpB protein 29 187 2.2E-50 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase UA74_25650 d8dd774ea124f1fea0fdee1f5b9d49cb 422 Gene3D G3DSA:3.40.50.150 216 420 2.1E-46 T 12-10-2018 UA74_19665 a97dd054654ae7286231f936ae106794 250 Gene3D G3DSA:2.40.10.10 119 249 1.5E-18 T 12-10-2018 UA74_19665 a97dd054654ae7286231f936ae106794 250 Pfam PF00089 Trypsin 50 244 5.0E-28 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_19665 a97dd054654ae7286231f936ae106794 250 Gene3D G3DSA:2.40.10.10 50 91 4.2E-11 T 12-10-2018 UA74_19665 a97dd054654ae7286231f936ae106794 250 SMART SM00020 49 244 2.2E-30 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_19665 a97dd054654ae7286231f936ae106794 250 SUPERFAMILY SSF50494 21 249 4.52E-43 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_19665 a97dd054654ae7286231f936ae106794 250 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 119 133 6.8E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_19665 a97dd054654ae7286231f936ae106794 250 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 195 207 6.8E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_19665 a97dd054654ae7286231f936ae106794 250 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 75 90 6.8E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_25995 5dd7398185d261c26ea0df2172a6ad07 307 SUPERFAMILY SSF52283 37 121 3.51E-5 T 12-10-2018 UA74_25995 5dd7398185d261c26ea0df2172a6ad07 307 Gene3D G3DSA:3.40.50.720 23 303 3.7E-71 T 12-10-2018 UA74_25995 5dd7398185d261c26ea0df2172a6ad07 307 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 272 7.5E-43 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_25995 5dd7398185d261c26ea0df2172a6ad07 307 SUPERFAMILY SSF51735 99 273 5.1E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25995 5dd7398185d261c26ea0df2172a6ad07 307 Gene3D G3DSA:3.40.50.720 97 279 3.7E-71 T 12-10-2018 UA74_23235 32d46683b4b682d725d74fbbf289d57b 321 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 5 311 1.1E-72 T 12-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain UA74_23235 32d46683b4b682d725d74fbbf289d57b 321 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 9 19 - T 12-10-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 UA74_23235 32d46683b4b682d725d74fbbf289d57b 321 Gene3D G3DSA:3.90.245.10 2 320 1.3E-87 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like UA74_23235 32d46683b4b682d725d74fbbf289d57b 321 SUPERFAMILY SSF53590 1 317 6.41E-81 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like UA74_14880 7f3708ed5946c00beed9c04a0179500a 168 Gene3D G3DSA:2.30.110.10 19 166 9.6E-32 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_14880 7f3708ed5946c00beed9c04a0179500a 168 SUPERFAMILY SSF50475 23 155 3.44E-25 T 12-10-2018 UA74_14880 7f3708ed5946c00beed9c04a0179500a 168 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 107 2.6E-14 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_06685 dacd6539be9b1b37f63e9a08b4fd22a2 447 Pfam PF00501 AMP-binding enzyme 56 436 4.3E-56 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_06685 dacd6539be9b1b37f63e9a08b4fd22a2 447 Gene3D G3DSA:3.40.50.12780 50 435 3.1E-73 T 12-10-2018 UA74_06685 dacd6539be9b1b37f63e9a08b4fd22a2 447 SUPERFAMILY SSF56801 41 440 1.96E-69 T 12-10-2018 UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 184 0.0031 T 12-10-2018 UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.3E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 Gene3D G3DSA:3.40.50.720 1 227 7.0E-58 T 12-10-2018 UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 SUPERFAMILY SSF51735 3 216 1.12E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 Pfam PF00106 short chain dehydrogenase 6 192 8.5E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10980 42550e9f6bcdc1c12b5bdf6bc035c2e5 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.7E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24695 5d30f859152c86d928ef39904b9f2679 731 SMART SM00220 25 286 3.3E-59 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Gene3D G3DSA:3.30.10.20 670 730 2.0E-6 T 12-10-2018 UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Gene3D G3DSA:3.30.200.20 14 108 8.6E-29 T 12-10-2018 UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Gene3D G3DSA:3.30.10.20 466 534 1.2E-10 T 12-10-2018 UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Gene3D G3DSA:3.30.10.20 535 602 1.4E-12 T 12-10-2018 UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Gene3D G3DSA:3.30.10.20 603 669 2.1E-14 T 12-10-2018 UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Pfam PF00069 Protein kinase domain 27 242 3.2E-45 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Gene3D G3DSA:1.10.510.10 110 293 1.5E-51 T 12-10-2018 UA74_24695 5d30f859152c86d928ef39904b9f2679 731 SMART SM00740 673 730 0.79 T 12-10-2018 IPR005543 PASTA domain UA74_24695 5d30f859152c86d928ef39904b9f2679 731 SMART SM00740 466 532 0.006 T 12-10-2018 IPR005543 PASTA domain UA74_24695 5d30f859152c86d928ef39904b9f2679 731 SMART SM00740 537 601 0.0038 T 12-10-2018 IPR005543 PASTA domain UA74_24695 5d30f859152c86d928ef39904b9f2679 731 SMART SM00740 602 670 8.1E-10 T 12-10-2018 IPR005543 PASTA domain UA74_24695 5d30f859152c86d928ef39904b9f2679 731 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 148 160 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Pfam PF03793 PASTA domain 675 729 9.4E-6 T 12-10-2018 IPR005543 PASTA domain UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Pfam PF03793 PASTA domain 472 532 7.3E-8 T 12-10-2018 IPR005543 PASTA domain UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Pfam PF03793 PASTA domain 606 669 3.6E-10 T 12-10-2018 IPR005543 PASTA domain UA74_24695 5d30f859152c86d928ef39904b9f2679 731 Pfam PF03793 PASTA domain 542 601 8.0E-10 T 12-10-2018 IPR005543 PASTA domain UA74_24695 5d30f859152c86d928ef39904b9f2679 731 SUPERFAMILY SSF56112 23 288 3.46E-73 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_19465 e610898d13acf5364c0f624215afbb60 301 SMART SM00418 24 110 5.4E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19465 e610898d13acf5364c0f624215afbb60 301 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 26 41 1.6E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19465 e610898d13acf5364c0f624215afbb60 301 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.6E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19465 e610898d13acf5364c0f624215afbb60 301 SUPERFAMILY SSF55729 123 279 2.3E-29 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_19465 e610898d13acf5364c0f624215afbb60 301 Gene3D G3DSA:1.10.10.10 6 111 3.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19465 e610898d13acf5364c0f624215afbb60 301 Pfam PF12840 Helix-turn-helix domain 24 83 8.9E-14 T 12-10-2018 UA74_19465 e610898d13acf5364c0f624215afbb60 301 Gene3D G3DSA:3.40.630.30 118 283 3.7E-38 T 12-10-2018 UA74_19465 e610898d13acf5364c0f624215afbb60 301 SUPERFAMILY SSF46785 20 93 3.09E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_19465 e610898d13acf5364c0f624215afbb60 301 Pfam PF13420 Acetyltransferase (GNAT) domain 125 272 6.4E-11 T 12-10-2018 UA74_30010 8d9921eb67dcb1c78b4e2b518ad1359e 168 Pfam PF00436 Single-strand binding protein family 6 106 1.4E-28 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 UA74_30010 8d9921eb67dcb1c78b4e2b518ad1359e 168 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 31.305 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UA74_30010 8d9921eb67dcb1c78b4e2b518ad1359e 168 SUPERFAMILY SSF50249 6 168 1.86E-46 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_30010 8d9921eb67dcb1c78b4e2b518ad1359e 168 Gene3D G3DSA:2.40.50.140 1 120 1.3E-42 T 12-10-2018 UA74_30010 8d9921eb67dcb1c78b4e2b518ad1359e 168 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 131 1.4E-32 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UA74_04100 37af19ab889c95c867bb336853ed2d62 479 Pfam PF00571 CBS domain 100 136 0.0026 T 12-10-2018 IPR000644 CBS domain UA74_04100 37af19ab889c95c867bb336853ed2d62 479 SMART SM01240 11 475 6.0E-189 T 12-10-2018 UA74_04100 37af19ab889c95c867bb336853ed2d62 479 Gene3D G3DSA:3.20.20.70 5 476 2.8E-136 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_04100 37af19ab889c95c867bb336853ed2d62 479 PIRSF PIRSF000130 3 479 1.4E-139 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 UA74_04100 37af19ab889c95c867bb336853ed2d62 479 SUPERFAMILY SSF54631 99 202 4.42E-15 T 12-10-2018 UA74_04100 37af19ab889c95c867bb336853ed2d62 479 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 474 4.4E-104 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 UA74_04100 37af19ab889c95c867bb336853ed2d62 479 SUPERFAMILY SSF51412 11 473 3.53E-91 T 12-10-2018 UA74_04100 37af19ab889c95c867bb336853ed2d62 479 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 477 5.1E-247 T 12-10-2018 IPR005991 IMP dehydrogenase-related 1 UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 ProSitePatterns PS00361 Ribosomal protein S10 signature. 44 59 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 Pfam PF00338 Ribosomal protein S10p/S20e 22 115 3.1E-34 T 12-10-2018 IPR027486 Ribosomal protein S10 domain UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 SMART SM01403 22 116 2.8E-55 T 12-10-2018 IPR027486 Ribosomal protein S10 domain UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 Gene3D G3DSA:3.30.70.600 7 116 2.5E-36 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 SUPERFAMILY SSF54999 20 115 2.22E-36 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 18 116 24.593 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 19 116 1.3E-45 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 PRINTS PR00971 Ribosomal protein S10 family signature 76 90 4.8E-21 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 PRINTS PR00971 Ribosomal protein S10 family signature 20 33 4.8E-21 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02940 892ce85bfbd4e779d5722bc8b2e7727e 116 PRINTS PR00971 Ribosomal protein S10 family signature 55 70 4.8E-21 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_07475 bf39b5d7374f1af4d30acd89c291a1a4 203 SUPERFAMILY SSF46689 23 95 8.48E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_07475 bf39b5d7374f1af4d30acd89c291a1a4 203 Gene3D G3DSA:1.10.357.10 15 203 6.6E-42 T 12-10-2018 UA74_07475 bf39b5d7374f1af4d30acd89c291a1a4 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 78 2.4E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_07475 bf39b5d7374f1af4d30acd89c291a1a4 203 SUPERFAMILY SSF48498 98 202 6.88E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_14035 29c3286f27687deb15ca38723d88493e 472 Gene3D G3DSA:3.40.50.300 49 260 1.3E-28 T 12-10-2018 UA74_14035 29c3286f27687deb15ca38723d88493e 472 SUPERFAMILY SSF52540 51 341 4.89E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14035 29c3286f27687deb15ca38723d88493e 472 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 190 243 1.3E-5 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 UA74_08610 2c790554f26cb8713ad411702e82da13 357 Pfam PF01715 IPP transferase 86 332 2.7E-70 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 UA74_08610 2c790554f26cb8713ad411702e82da13 357 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 54 338 6.9E-71 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 UA74_08610 2c790554f26cb8713ad411702e82da13 357 Gene3D G3DSA:1.10.20.140 160 230 3.8E-86 T 12-10-2018 UA74_08610 2c790554f26cb8713ad411702e82da13 357 SUPERFAMILY SSF52540 53 197 3.22E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08610 2c790554f26cb8713ad411702e82da13 357 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 53 348 26.373 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 UA74_08610 2c790554f26cb8713ad411702e82da13 357 Gene3D G3DSA:3.40.50.300 57 336 3.8E-86 T 12-10-2018 UA74_04890 7f04aea8d3e87c972c3be05bbc4a6a76 339 Gene3D G3DSA:2.30.42.10 135 205 3.8E-14 T 12-10-2018 UA74_04890 7f04aea8d3e87c972c3be05bbc4a6a76 339 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 234 316 7.9E-11 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 UA74_04890 7f04aea8d3e87c972c3be05bbc4a6a76 339 SUPERFAMILY SSF54211 222 326 4.55E-20 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_04890 7f04aea8d3e87c972c3be05bbc4a6a76 339 Pfam PF13180 PDZ domain 135 198 4.2E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 UA74_04890 7f04aea8d3e87c972c3be05bbc4a6a76 339 SUPERFAMILY SSF50156 133 234 1.97E-15 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 UA74_04890 7f04aea8d3e87c972c3be05bbc4a6a76 339 SMART SM00228 80 191 1.0E-5 T 12-10-2018 IPR001478 PDZ domain GO:0005515 UA74_04890 7f04aea8d3e87c972c3be05bbc4a6a76 339 Gene3D G3DSA:3.30.230.10 206 331 6.4E-22 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_17555 02f1fec1c527168ed804afabfef63149 228 Gene3D G3DSA:3.40.50.150 14 227 3.6E-64 T 12-10-2018 UA74_17555 02f1fec1c527168ed804afabfef63149 228 Pfam PF01596 O-methyltransferase 26 227 3.4E-50 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 UA74_17555 02f1fec1c527168ed804afabfef63149 228 SUPERFAMILY SSF53335 14 228 4.56E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_13550 82c644b3288fe824046791f2ab3c8407 395 SUPERFAMILY SSF53901 5 271 1.98E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 Gene3D G3DSA:3.40.47.10 141 392 1.1E-146 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 Pfam PF00108 Thiolase, N-terminal domain 5 264 7.2E-76 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 Pfam PF02803 Thiolase, C-terminal domain 273 393 1.8E-42 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 Gene3D G3DSA:3.40.47.10 7 278 1.1E-146 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 9.2E-135 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 PIRSF PIRSF000429 1 395 9.8E-131 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 UA74_13550 82c644b3288fe824046791f2ab3c8407 395 SUPERFAMILY SSF53901 274 393 1.13E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 Gene3D G3DSA:3.40.1770.10 13 537 5.5E-243 T 12-10-2018 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 ProSitePatterns PS01233 Urocanase signature. 437 452 - T 12-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 548 1.3E-273 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 Hamap MF_00577 Urocanate hydratase [hutU]. 3 551 49.92 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 PIRSF PIRSF001423 2 553 2.3E-273 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 Gene3D G3DSA:3.40.50.10730 138 344 5.5E-243 T 12-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 Pfam PF17391 Urocanase N-terminal domain 8 134 4.7E-59 T 12-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 Pfam PF17392 Urocanase C-terminal domain 347 541 4.7E-92 T 12-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 Pfam PF01175 Urocanase Rossmann-like domain 137 344 1.2E-82 T 12-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26325 eb4f0b02d3e99e8feb145414f62a5b5e 553 SUPERFAMILY SSF111326 5 549 1.44E-245 T 12-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_11445 f77dd6930c95290934ff9280b43a671d 446 Gene3D G3DSA:1.20.120.450 8 155 2.1E-9 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_11445 f77dd6930c95290934ff9280b43a671d 446 SUPERFAMILY SSF56436 180 440 1.28E-77 T 12-10-2018 IPR016187 C-type lectin fold UA74_11445 f77dd6930c95290934ff9280b43a671d 446 SUPERFAMILY SSF109854 15 148 6.96E-21 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_11445 f77dd6930c95290934ff9280b43a671d 446 Pfam PF03781 Sulfatase-modifying factor enzyme 1 179 438 1.4E-65 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 UA74_11445 f77dd6930c95290934ff9280b43a671d 446 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 440 52.561 T 12-10-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 UA74_11445 f77dd6930c95290934ff9280b43a671d 446 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 19 437 1.0E-134 T 12-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 UA74_11445 f77dd6930c95290934ff9280b43a671d 446 Gene3D G3DSA:3.90.1580.10 174 445 4.8E-64 T 12-10-2018 UA74_11445 f77dd6930c95290934ff9280b43a671d 446 Pfam PF12867 DinB superfamily 21 152 1.3E-26 T 12-10-2018 IPR024775 DinB-like domain UA74_08000 7e9f3927556cd79bccc79486916580a5 268 SUPERFAMILY SSF53850 47 268 4.48E-53 T 12-10-2018 UA74_08000 7e9f3927556cd79bccc79486916580a5 268 Gene3D G3DSA:3.40.190.10 126 228 9.0E-57 T 12-10-2018 UA74_08000 7e9f3927556cd79bccc79486916580a5 268 Gene3D G3DSA:3.40.190.10 49 265 9.0E-57 T 12-10-2018 UA74_08000 7e9f3927556cd79bccc79486916580a5 268 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 53 264 6.9E-36 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 UA74_08000 7e9f3927556cd79bccc79486916580a5 268 PIRSF PIRSF004846 6 268 5.9E-60 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 UA74_08000 7e9f3927556cd79bccc79486916580a5 268 Pfam PF13531 Bacterial extracellular solute-binding protein 48 265 4.5E-39 T 12-10-2018 UA74_30175 02bc6064ba9cd0b664f1f56be0d7f2c4 87 Pfam PF00462 Glutaredoxin 4 61 1.6E-13 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 UA74_30175 02bc6064ba9cd0b664f1f56be0d7f2c4 87 Gene3D G3DSA:3.40.30.10 1 82 4.0E-17 T 12-10-2018 UA74_30175 02bc6064ba9cd0b664f1f56be0d7f2c4 87 SUPERFAMILY SSF52833 4 75 5.51E-14 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_04600 f0391cd5462161b0719c0eb3201007e1 398 SUPERFAMILY SSF117916 28 111 5.56E-22 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UA74_04600 f0391cd5462161b0719c0eb3201007e1 398 SUPERFAMILY SSF52540 133 379 3.43E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04600 f0391cd5462161b0719c0eb3201007e1 398 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 134 379 1.0E-87 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 UA74_04600 f0391cd5462161b0719c0eb3201007e1 398 Gene3D G3DSA:3.40.50.300 129 378 1.3E-68 T 12-10-2018 UA74_04600 f0391cd5462161b0719c0eb3201007e1 398 Hamap MF_02040 Iron-sulfur cluster carrier protein. 125 380 33.288 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein UA74_04600 f0391cd5462161b0719c0eb3201007e1 398 ProSitePatterns PS01215 Mrp family signature. 238 254 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 UA74_04600 f0391cd5462161b0719c0eb3201007e1 398 Pfam PF01883 Iron-sulfur cluster assembly protein 29 99 4.2E-18 T 12-10-2018 IPR002744 MIP18 family-like UA74_04600 f0391cd5462161b0719c0eb3201007e1 398 Gene3D G3DSA:3.30.300.130 22 117 7.5E-21 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UA74_12595 8766f6af5411c645a44900dde2af6337 520 Pfam PF01966 HD domain 57 138 3.8E-11 T 12-10-2018 IPR006674 HD domain UA74_12595 8766f6af5411c645a44900dde2af6337 520 SMART SM00471 53 260 3.2E-10 T 12-10-2018 IPR003607 HD/PDEase domain UA74_12595 8766f6af5411c645a44900dde2af6337 520 SUPERFAMILY SSF109604 20 274 1.42E-44 T 12-10-2018 UA74_12595 8766f6af5411c645a44900dde2af6337 520 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 21 506 2.2E-56 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 UA74_12595 8766f6af5411c645a44900dde2af6337 520 Gene3D G3DSA:1.10.3210.10 2 508 5.2E-61 T 12-10-2018 UA74_14695 be9a34f2c0396688619aebee57f34d9d 553 Gene3D G3DSA:3.60.110.10 258 513 4.8E-21 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UA74_14695 be9a34f2c0396688619aebee57f34d9d 553 SUPERFAMILY SSF56317 242 512 3.92E-42 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UA74_14695 be9a34f2c0396688619aebee57f34d9d 553 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 74 482 2.5E-73 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UA74_14695 be9a34f2c0396688619aebee57f34d9d 553 Pfam PF00795 Carbon-nitrogen hydrolase 317 506 4.5E-18 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 UA74_14695 be9a34f2c0396688619aebee57f34d9d 553 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 27 520 15.383 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 Gene3D G3DSA:3.30.413.10 621 777 5.6E-35 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 Gene3D G3DSA:3.50.50.60 6 299 5.8E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 SUPERFAMILY SSF51905 148 309 3.02E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00397 Sirohaem Fe-binding site signature 626 644 1.2E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00397 Sirohaem Fe-binding site signature 669 687 1.2E-6 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 5 791 0.0 T 12-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 Gene3D G3DSA:1.10.10.1100 417 470 1.1E-11 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 282 6.1E-48 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 SUPERFAMILY SSF56014 623 797 7.46E-51 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PIRSF PIRSF037149 1 825 0.0 T 12-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 SUPERFAMILY SSF55124 492 631 4.42E-24 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 622 758 1.3E-20 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 4.1E-5 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 4.1E-5 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.1E-5 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 Gene3D G3DSA:3.50.50.60 114 240 5.8E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.0E-17 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 6.0E-17 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 6.0E-17 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 6.0E-17 T 12-10-2018 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 550 612 6.0E-11 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 669 685 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 SUPERFAMILY SSF51905 2 187 2.64E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09370 bbdc33bfe07bcd7925462c4079314705 833 Pfam PF04324 BFD-like [2Fe-2S] binding domain 418 466 3.5E-12 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain UA74_10090 4faa49ace235a770dca18db34b9666ec 1132 SUPERFAMILY SSF56300 783 999 1.54E-26 T 12-10-2018 UA74_10090 4faa49ace235a770dca18db34b9666ec 1132 Gene3D G3DSA:3.60.21.10 772 1040 9.0E-27 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_10090 4faa49ace235a770dca18db34b9666ec 1132 Pfam PF00149 Calcineurin-like phosphoesterase 783 975 2.7E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UA74_10090 4faa49ace235a770dca18db34b9666ec 1132 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 574 585 - T 12-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 UA74_10090 4faa49ace235a770dca18db34b9666ec 1132 Pfam PF09992 Phosphodiester glycosidase 259 411 1.0E-29 T 12-10-2018 IPR018711 Phosphodiester glycosidase UA74_02950 50757f47f457d013bb83f50391353b61 236 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 10 209 32.496 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02950 50757f47f457d013bb83f50391353b61 236 Pfam PF00573 Ribosomal protein L4/L1 family 18 204 5.9E-63 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 UA74_02950 50757f47f457d013bb83f50391353b61 236 SUPERFAMILY SSF52166 4 205 1.44E-72 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 UA74_02950 50757f47f457d013bb83f50391353b61 236 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 204 1.2E-68 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02950 50757f47f457d013bb83f50391353b61 236 Gene3D G3DSA:3.40.1370.10 3 211 1.5E-73 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 UA74_06985 f8009baedd063731eea4eb032208c4d2 680 Hamap MF_01884 Transcription termination factor Rho [rho]. 300 673 191.981 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 UA74_06985 f8009baedd063731eea4eb032208c4d2 680 SMART SM00357 308 375 1.1E-6 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 UA74_06985 f8009baedd063731eea4eb032208c4d2 680 Gene3D G3DSA:2.40.50.140 266 386 4.3E-30 T 12-10-2018 UA74_06985 f8009baedd063731eea4eb032208c4d2 680 SUPERFAMILY SSF68912 53 89 5.89E-5 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily UA74_06985 f8009baedd063731eea4eb032208c4d2 680 Pfam PF07498 Rho termination factor, N-terminal domain 53 89 1.3E-10 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 UA74_06985 f8009baedd063731eea4eb032208c4d2 680 TIGRFAM TIGR00767 rho: transcription termination factor Rho 52 671 4.1E-192 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 UA74_06985 f8009baedd063731eea4eb032208c4d2 680 SMART SM00959 52 94 1.8E-9 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 UA74_06985 f8009baedd063731eea4eb032208c4d2 680 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 413 617 6.1E-22 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_06985 f8009baedd063731eea4eb032208c4d2 680 SMART SM00382 424 609 1.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_06985 f8009baedd063731eea4eb032208c4d2 680 Gene3D G3DSA:3.40.50.300 387 676 1.5E-118 T 12-10-2018 UA74_06985 f8009baedd063731eea4eb032208c4d2 680 SUPERFAMILY SSF52540 344 625 9.56E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_06985 f8009baedd063731eea4eb032208c4d2 680 Pfam PF07497 Rho termination factor, RNA-binding domain 307 382 1.0E-28 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 UA74_18070 3f47495cb179e9d5138917ea77f304a3 119 SMART SM00422 1 69 9.5E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_18070 3f47495cb179e9d5138917ea77f304a3 119 SUPERFAMILY SSF46955 1 117 1.94E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_18070 3f47495cb179e9d5138917ea77f304a3 119 Gene3D G3DSA:1.10.1660.10 1 118 1.2E-24 T 12-10-2018 UA74_18070 3f47495cb179e9d5138917ea77f304a3 119 Pfam PF13411 MerR HTH family regulatory protein 1 67 3.0E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_18070 3f47495cb179e9d5138917ea77f304a3 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.4E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_18070 3f47495cb179e9d5138917ea77f304a3 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.4E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_18070 3f47495cb179e9d5138917ea77f304a3 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.4E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 Gene3D G3DSA:2.60.40.420 446 674 2.9E-53 T 12-10-2018 IPR008972 Cupredoxin UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 Gene3D G3DSA:2.60.40.420 268 443 1.1E-53 T 12-10-2018 IPR008972 Cupredoxin UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 Pfam PF07732 Multicopper oxidase 128 161 8.7E-5 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 Pfam PF07732 Multicopper oxidase 204 270 5.3E-6 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 Gene3D G3DSA:2.60.40.420 82 267 3.7E-55 T 12-10-2018 IPR008972 Cupredoxin UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 SUPERFAMILY SSF49503 94 272 1.21E-21 T 12-10-2018 IPR008972 Cupredoxin UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 SUPERFAMILY SSF49503 275 656 1.57E-31 T 12-10-2018 IPR008972 Cupredoxin UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 ProSitePatterns PS00079 Multicopper oxidases signature 1. 629 649 - T 12-10-2018 IPR033138 Multicopper oxidases, conserved site UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 ProSitePatterns PS00080 Multicopper oxidases signature 2. 634 645 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 UA74_11470 c8ea70efec7a3bbdc724ce13b59bee7e 674 Pfam PF07731 Multicopper oxidase 524 654 1.8E-22 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SMART SM00382 99 303 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Gene3D G3DSA:1.10.260.30 312 437 1.2E-38 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Gene3D G3DSA:3.40.50.300 90 287 8.3E-120 T 12-10-2018 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SMART SM00963 1 86 5.1E-33 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 1.8E-69 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SUPERFAMILY SSF47446 330 430 8.67E-32 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Pfam PF02978 Signal peptide binding domain 330 427 1.6E-28 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SUPERFAMILY SSF52540 42 356 7.3E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 4.4E-177 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Gene3D G3DSA:1.20.120.140 5 308 8.3E-120 T 12-10-2018 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 SMART SM00962 100 298 1.2E-109 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 440 33.338 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 UA74_08805 9b4457e6ba0aaaf6d1dedfbdab00338d 526 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.1E-20 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_18940 f738d3fc234eec52a24c3dc804ff6afe 113 Pfam PF00085 Thioredoxin 4 102 8.0E-25 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 UA74_18940 f738d3fc234eec52a24c3dc804ff6afe 113 PIRSF PIRSF000077 1 104 2.9E-27 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_18940 f738d3fc234eec52a24c3dc804ff6afe 113 SUPERFAMILY SSF52833 3 103 9.93E-32 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_18940 f738d3fc234eec52a24c3dc804ff6afe 113 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_18940 f738d3fc234eec52a24c3dc804ff6afe 113 Gene3D G3DSA:3.40.30.10 2 112 1.8E-28 T 12-10-2018 UA74_18940 f738d3fc234eec52a24c3dc804ff6afe 113 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 1.2E-29 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_18940 f738d3fc234eec52a24c3dc804ff6afe 113 PRINTS PR00421 Thioredoxin family signature 29 38 2.4E-8 T 12-10-2018 UA74_18940 f738d3fc234eec52a24c3dc804ff6afe 113 PRINTS PR00421 Thioredoxin family signature 21 29 2.4E-8 T 12-10-2018 UA74_18940 f738d3fc234eec52a24c3dc804ff6afe 113 PRINTS PR00421 Thioredoxin family signature 68 79 2.4E-8 T 12-10-2018 UA74_27530 6fd134ce0c0c9fde8214872ad4a8ad3c 213 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 120 198 2.0E-23 T 12-10-2018 IPR000772 Ricin B, lectin domain UA74_27530 6fd134ce0c0c9fde8214872ad4a8ad3c 213 SUPERFAMILY SSF50370 76 209 5.67E-41 T 12-10-2018 IPR035992 Ricin B-like lectins UA74_27530 6fd134ce0c0c9fde8214872ad4a8ad3c 213 Gene3D G3DSA:2.80.10.50 43 111 8.2E-9 T 12-10-2018 UA74_27530 6fd134ce0c0c9fde8214872ad4a8ad3c 213 SMART SM00458 73 211 4.9E-12 T 12-10-2018 IPR000772 Ricin B, lectin domain UA74_27530 6fd134ce0c0c9fde8214872ad4a8ad3c 213 Gene3D G3DSA:2.80.10.50 112 165 1.1E-15 T 12-10-2018 UA74_27530 6fd134ce0c0c9fde8214872ad4a8ad3c 213 Gene3D G3DSA:2.80.10.50 166 211 1.1E-16 T 12-10-2018 UA74_08590 b333d72bcaca24f802295f5917780aa1 480 Gene3D G3DSA:3.80.30.20 131 365 1.6E-89 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UA74_08590 b333d72bcaca24f802295f5917780aa1 480 SUPERFAMILY SSF102114 119 358 3.53E-60 T 12-10-2018 UA74_08590 b333d72bcaca24f802295f5917780aa1 480 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 1 429 1.3E-139 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 UA74_08590 b333d72bcaca24f802295f5917780aa1 480 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 137 157 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 UA74_08590 b333d72bcaca24f802295f5917780aa1 480 Pfam PF00919 Uncharacterized protein family UPF0004 1 90 8.3E-21 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 UA74_08590 b333d72bcaca24f802295f5917780aa1 480 Gene3D G3DSA:3.40.50.12160 1 120 4.9E-26 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily UA74_08590 b333d72bcaca24f802295f5917780aa1 480 SMART SM00729 133 351 8.1E-59 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_08590 b333d72bcaca24f802295f5917780aa1 480 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 434 64.228 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 UA74_08590 b333d72bcaca24f802295f5917780aa1 480 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 1 401 1.2E-132 T 12-10-2018 UA74_08590 b333d72bcaca24f802295f5917780aa1 480 Pfam PF04055 Radical SAM superfamily 137 308 6.6E-30 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Pfam PF06439 Domain of Unknown Function (DUF1080) 1045 1220 2.5E-28 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Gene3D G3DSA:2.60.40.10 485 577 8.6E-21 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Gene3D G3DSA:2.60.120.560 1036 1221 7.7E-31 T 12-10-2018 UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 SUPERFAMILY SSF49785 693 815 7.82E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 SUPERFAMILY SSF50952 54 472 7.19E-30 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 SMART SM00606 688 817 4.4E-12 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 SMART SM00089 493 580 4.3E-14 T 12-10-2018 IPR022409 PKD/Chitinase domain UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 SMART SM00089 825 905 9.3E-11 T 12-10-2018 IPR022409 PKD/Chitinase domain UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Pfam PF03422 Carbohydrate binding module (family 6) 696 816 3.0E-15 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Gene3D G3DSA:2.120.10.30 49 442 1.1E-75 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 SUPERFAMILY SSF49299 826 907 3.79E-14 T 12-10-2018 IPR035986 PKD domain superfamily UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Gene3D G3DSA:2.60.120.260 688 816 5.1E-19 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Pfam PF00801 PKD domain 500 569 5.4E-10 T 12-10-2018 IPR000601 PKD domain UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Pfam PF00801 PKD domain 839 892 7.2E-10 T 12-10-2018 IPR000601 PKD domain UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Gene3D G3DSA:2.60.40.10 822 904 2.5E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 Pfam PF07995 Glucose / Sorbosone dehydrogenase 71 324 5.9E-34 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase UA74_12660 c5a1345ed9d9c9cf094c8a5e89536e87 1591 SUPERFAMILY SSF49299 494 579 3.66E-17 T 12-10-2018 IPR035986 PKD domain superfamily UA74_11315 86f4d09edf5fed6150ec2fded22c5393 182 SUPERFAMILY SSF54637 16 164 3.82E-41 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_11315 86f4d09edf5fed6150ec2fded22c5393 182 Pfam PF03061 Thioesterase superfamily 31 102 1.9E-17 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 UA74_11315 86f4d09edf5fed6150ec2fded22c5393 182 Gene3D G3DSA:3.10.129.10 4 168 1.4E-50 T 12-10-2018 UA74_29480 17392d96e812796f42944ce5bc1621e0 146 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 140 4.9E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_29480 17392d96e812796f42944ce5bc1621e0 146 SMART SM00421 92 144 0.0098 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_29480 17392d96e812796f42944ce5bc1621e0 146 SUPERFAMILY SSF88946 2 65 1.57E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_29480 17392d96e812796f42944ce5bc1621e0 146 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 1 140 1.5E-47 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_29480 17392d96e812796f42944ce5bc1621e0 146 SUPERFAMILY SSF88659 70 144 2.99E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_29480 17392d96e812796f42944ce5bc1621e0 146 Gene3D G3DSA:1.10.10.10 60 145 3.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_29480 17392d96e812796f42944ce5bc1621e0 146 Pfam PF08281 Sigma-70, region 4 86 138 9.5E-20 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_29480 17392d96e812796f42944ce5bc1621e0 146 Pfam PF04542 Sigma-70 region 2 7 59 5.3E-6 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_29480 17392d96e812796f42944ce5bc1621e0 146 Gene3D G3DSA:1.10.1740.10 1 59 6.2E-7 T 12-10-2018 UA74_15290 b5b5dc145e6408f9e6c38b7617f8281d 416 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 165 7.7E-14 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_15290 b5b5dc145e6408f9e6c38b7617f8281d 416 Pfam PF08281 Sigma-70, region 4 114 165 3.4E-9 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_15290 b5b5dc145e6408f9e6c38b7617f8281d 416 SUPERFAMILY SSF88946 6 86 3.14E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_15290 b5b5dc145e6408f9e6c38b7617f8281d 416 Pfam PF04542 Sigma-70 region 2 10 76 6.9E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_15290 b5b5dc145e6408f9e6c38b7617f8281d 416 Gene3D G3DSA:1.10.1740.10 4 96 1.8E-6 T 12-10-2018 UA74_15290 b5b5dc145e6408f9e6c38b7617f8281d 416 SUPERFAMILY SSF88659 107 165 1.07E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_15290 b5b5dc145e6408f9e6c38b7617f8281d 416 Gene3D G3DSA:1.10.10.10 117 169 1.1E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26580 f845eeba3acecf1253774dbdd1b3c44b 78 Gene3D G3DSA:2.20.25.10 12 61 4.3E-12 T 12-10-2018 UA74_26580 f845eeba3acecf1253774dbdd1b3c44b 78 SUPERFAMILY SSF158997 6 61 3.27E-13 T 12-10-2018 UA74_26580 f845eeba3acecf1253774dbdd1b3c44b 78 Pfam PF03966 Trm112p-like protein 6 50 1.1E-5 T 12-10-2018 IPR005651 Trm112-like UA74_18030 7b984b01f0c05b656286dae636f3957b 183 SUPERFAMILY SSF109854 12 171 5.95E-31 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_18030 7b984b01f0c05b656286dae636f3957b 183 Gene3D G3DSA:1.20.120.450 6 174 7.7E-56 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_18030 7b984b01f0c05b656286dae636f3957b 183 Pfam PF04978 Protein of unknown function (DUF664) 13 172 2.3E-19 T 12-10-2018 IPR007061 Protein of unknown function DUF664 UA74_14540 31a9f4ee0d2315e447288c40f8f7c4ed 423 SUPERFAMILY SSF51445 84 349 9.31E-25 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_14540 31a9f4ee0d2315e447288c40f8f7c4ed 423 Pfam PF02638 Glycosyl hydrolase-like 10 56 368 6.2E-91 T 12-10-2018 IPR003790 Glycosyl hydrolase-like 10 UA74_14540 31a9f4ee0d2315e447288c40f8f7c4ed 423 Gene3D G3DSA:3.20.20.70 79 253 1.4E-11 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_18950 4cb7cdb91e344d08285c0ff2a7d2c98f 323 Gene3D G3DSA:1.10.150.130 34 125 3.3E-8 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_18950 4cb7cdb91e344d08285c0ff2a7d2c98f 323 Gene3D G3DSA:1.10.443.10 139 316 9.0E-35 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_18950 4cb7cdb91e344d08285c0ff2a7d2c98f 323 Pfam PF00589 Phage integrase family 141 313 2.1E-30 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_18950 4cb7cdb91e344d08285c0ff2a7d2c98f 323 SUPERFAMILY SSF56349 35 312 2.0E-34 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_18950 4cb7cdb91e344d08285c0ff2a7d2c98f 323 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 39 121 6.8E-6 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_05080 852cc58c8459b0162d1473b577eb7267 381 SUPERFAMILY SSF53756 5 373 1.33E-39 T 12-10-2018 UA74_05080 852cc58c8459b0162d1473b577eb7267 381 Gene3D G3DSA:3.40.50.2000 4 176 6.1E-13 T 12-10-2018 UA74_05080 852cc58c8459b0162d1473b577eb7267 381 Gene3D G3DSA:3.40.50.2000 211 356 3.6E-19 T 12-10-2018 UA74_05080 852cc58c8459b0162d1473b577eb7267 381 Pfam PF00534 Glycosyl transferases group 1 264 330 8.6E-12 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_05080 852cc58c8459b0162d1473b577eb7267 381 Pfam PF13439 Glycosyltransferase Family 4 19 170 7.1E-12 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SUPERFAMILY SSF141868 795 1040 6.67E-77 T 12-10-2018 IPR035919 EAL domain superfamily UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Pfam PF00563 EAL domain 796 1030 3.2E-63 T 12-10-2018 IPR001633 EAL domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Gene3D G3DSA:3.30.450.20 366 433 1.3E-14 T 12-10-2018 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Gene3D G3DSA:3.30.450.20 120 187 5.4E-9 T 12-10-2018 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SMART SM00052 790 1035 1.6E-87 T 12-10-2018 IPR001633 EAL domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SMART SM00086 196 238 8.4E-5 T 12-10-2018 IPR001610 PAC motif UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SMART SM00086 442 483 2.9 T 12-10-2018 IPR001610 PAC motif UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SMART SM00086 316 357 3.2 T 12-10-2018 IPR001610 PAC motif UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SMART SM00086 569 610 6.0 T 12-10-2018 IPR001610 PAC motif UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SMART SM00091 495 561 3.7E-8 T 12-10-2018 IPR000014 PAS domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SMART SM00091 366 436 12.0 T 12-10-2018 IPR000014 PAS domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SMART SM00091 17 85 29.0 T 12-10-2018 IPR000014 PAS domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SUPERFAMILY SSF55785 169 239 8.38E-9 T 12-10-2018 IPR035965 PAS domain superfamily UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SMART SM00267 610 780 4.1E-51 T 12-10-2018 IPR000160 GGDEF domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Gene3D G3DSA:2.10.70.100 438 484 1.9E-8 T 12-10-2018 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Gene3D G3DSA:2.10.70.100 193 239 1.5E-8 T 12-10-2018 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Pfam PF08448 PAS fold 505 612 3.9E-12 T 12-10-2018 IPR013656 PAS fold-4 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Gene3D G3DSA:3.30.450.20 493 620 6.1E-21 T 12-10-2018 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Gene3D G3DSA:3.20.20.450 793 1042 4.1E-84 T 12-10-2018 IPR035919 EAL domain superfamily UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Gene3D G3DSA:3.30.450.20 241 355 2.0E-7 T 12-10-2018 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 493 617 3.8E-19 T 12-10-2018 IPR000014 PAS domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 381 489 8.5E-7 T 12-10-2018 IPR000014 PAS domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Pfam PF00990 Diguanylate cyclase, GGDEF domain 621 775 8.8E-34 T 12-10-2018 IPR000160 GGDEF domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Pfam PF08447 PAS fold 392 476 4.4E-12 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Pfam PF08447 PAS fold 146 232 9.0E-7 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 617 779 1.9E-32 T 12-10-2018 IPR000160 GGDEF domain UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SUPERFAMILY SSF55073 626 779 4.71E-38 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SUPERFAMILY SSF55785 481 608 8.05E-20 T 12-10-2018 IPR035965 PAS domain superfamily UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 Gene3D G3DSA:3.30.70.270 621 792 5.5E-47 T 12-10-2018 UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SUPERFAMILY SSF55785 291 365 2.62E-5 T 12-10-2018 IPR035965 PAS domain superfamily UA74_26380 a58ddbbb8f5073c6c5f4cf43cce57916 1051 SUPERFAMILY SSF55785 354 481 3.14E-18 T 12-10-2018 IPR035965 PAS domain superfamily UA74_04765 7ad55cb353d1a4221ca56a37ab856fde 109 Gene3D G3DSA:1.10.10.10 3 100 1.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04765 7ad55cb353d1a4221ca56a37ab856fde 109 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 7 80 4.3E-15 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_04765 7ad55cb353d1a4221ca56a37ab856fde 109 SUPERFAMILY SSF46767 5 80 2.35E-14 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 UA74_00700 4135668b04b5de3bb144ed5fa96267af 272 SUPERFAMILY SSF52540 41 242 3.08E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00700 4135668b04b5de3bb144ed5fa96267af 272 Pfam PF00005 ABC transporter 47 177 2.2E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_00700 4135668b04b5de3bb144ed5fa96267af 272 SMART SM00382 56 228 2.8E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_00700 4135668b04b5de3bb144ed5fa96267af 272 Gene3D G3DSA:3.40.50.300 34 257 2.0E-41 T 12-10-2018 UA74_23030 c80d6bde1f0c3f72cd896c4828fe50c5 282 Pfam PF13560 Helix-turn-helix domain 14 65 4.6E-11 T 12-10-2018 UA74_23030 c80d6bde1f0c3f72cd896c4828fe50c5 282 SUPERFAMILY SSF47413 11 72 1.18E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_23030 c80d6bde1f0c3f72cd896c4828fe50c5 282 SMART SM00530 17 72 1.1E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_23030 c80d6bde1f0c3f72cd896c4828fe50c5 282 Gene3D G3DSA:1.10.260.40 9 90 4.0E-11 T 12-10-2018 UA74_15180 2a2a7516a291c30e18fbdf829e60087c 199 SUPERFAMILY SSF48498 83 197 2.08E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_15180 2a2a7516a291c30e18fbdf829e60087c 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 57 2.5E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15180 2a2a7516a291c30e18fbdf829e60087c 199 SUPERFAMILY SSF46689 1 68 7.18E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_15180 2a2a7516a291c30e18fbdf829e60087c 199 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 85 196 1.2E-9 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal UA74_15180 2a2a7516a291c30e18fbdf829e60087c 199 Gene3D G3DSA:1.10.357.10 1 194 1.0E-42 T 12-10-2018 UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 ProSitePatterns PS00211 ABC transporters family signature. 200 214 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 SUPERFAMILY SSF52540 404 576 3.5E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 Gene3D G3DSA:3.40.50.300 483 577 3.2E-22 T 12-10-2018 UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 Gene3D G3DSA:3.40.50.300 399 482 6.9E-16 T 12-10-2018 UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 Gene3D G3DSA:3.40.50.300 45 361 9.6E-64 T 12-10-2018 UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 SUPERFAMILY SSF52540 51 273 7.67E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 Pfam PF00005 ABC transporter 402 529 1.1E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 SMART SM00382 410 574 9.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 SMART SM00382 65 273 2.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_06570 be3449de9fb4cfa573386dd6de8b5245 577 Pfam PF00005 ABC transporter 56 228 1.9E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 Pfam PF00575 S1 RNA binding domain 658 727 2.5E-18 T 12-10-2018 IPR003029 S1 domain GO:0003676 UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 Pfam PF16921 Tex protein YqgF-like domain 333 458 1.8E-50 T 12-10-2018 IPR032639 Tex protein, YqgF-like domain UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 Pfam PF12836 Helix-hairpin-helix motif 498 562 5.0E-28 T 12-10-2018 UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:1.10.150.310 506 637 1.9E-46 T 12-10-2018 UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF47781 477 565 1.22E-26 T 12-10-2018 IPR010994 RuvA domain 2-like UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF47781 567 638 1.58E-17 T 12-10-2018 IPR010994 RuvA domain 2-like UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF158832 3 327 2.62E-116 T 12-10-2018 UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF50249 645 731 6.56E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 SUPERFAMILY SSF53098 328 476 3.57E-50 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 SMART SM00316 656 727 4.3E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:1.10.3500.10 112 505 1.3E-149 T 12-10-2018 IPR023323 Tex-like domain superfamily UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:3.30.420.140 331 458 1.3E-149 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:1.10.10.650 2 109 3.9E-39 T 12-10-2018 IPR023319 Tex-like protein, HTH domain superfamily UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 Pfam PF09371 Tex-like protein N-terminal domain 9 192 3.2E-68 T 12-10-2018 IPR018974 Tex-like protein, N-terminal UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 Gene3D G3DSA:2.40.50.140 638 731 6.8E-26 T 12-10-2018 UA74_23225 4080b3d11b56e2a9c8b7d32b4d775579 818 SMART SM00732 332 431 2.7E-37 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 UA74_25545 bc5cfd38336ec68c755ca74498c9ab49 115 Gene3D G3DSA:3.40.33.10 1 114 3.3E-44 T 12-10-2018 IPR035940 CAP superfamily UA74_25545 bc5cfd38336ec68c755ca74498c9ab49 115 SUPERFAMILY SSF55797 2 114 5.06E-23 T 12-10-2018 IPR035940 CAP superfamily UA74_25545 bc5cfd38336ec68c755ca74498c9ab49 115 Pfam PF00188 Cysteine-rich secretory protein family 3 113 1.6E-19 T 12-10-2018 IPR014044 CAP domain UA74_22840 4533a35f048135fa6421400696638d93 227 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 196 6.0E-25 T 12-10-2018 UA74_22840 4533a35f048135fa6421400696638d93 227 Gene3D G3DSA:1.20.1440.100 20 96 1.0E-58 T 12-10-2018 UA74_22840 4533a35f048135fa6421400696638d93 227 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 8 210 1.9E-37 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like UA74_22840 4533a35f048135fa6421400696638d93 227 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 8 198 2.3E-17 T 12-10-2018 UA74_22840 4533a35f048135fa6421400696638d93 227 Gene3D G3DSA:3.40.50.1000 9 220 1.0E-58 T 12-10-2018 IPR023214 HAD superfamily UA74_22840 4533a35f048135fa6421400696638d93 227 SUPERFAMILY SSF56784 4 219 8.26E-23 T 12-10-2018 IPR036412 HAD-like superfamily UA74_11410 05ea48b3e6becd470b03c922579660d3 424 Gene3D G3DSA:3.30.930.10 105 424 7.9E-109 T 12-10-2018 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 SUPERFAMILY SSF55681 122 423 4.68E-91 T 12-10-2018 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 3.0E-18 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 224 400 6.6E-33 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 PIRSF PIRSF001529 1 423 3.1E-141 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 12 417 9.3E-134 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 Gene3D G3DSA:1.10.287.40 1 104 5.6E-13 T 12-10-2018 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 265 277 2.4E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 277 290 2.4E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 317 330 2.4E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 352 368 2.4E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 PRINTS PR00981 Seryl-tRNA synthetase signature 334 350 2.4E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 36.725 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UA74_11410 05ea48b3e6becd470b03c922579660d3 424 SUPERFAMILY SSF46589 1 112 3.19E-19 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 UA74_07160 478dbf83e117066a636fa61cf5891410 236 Gene3D G3DSA:1.25.40.340 4 210 3.2E-58 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_07160 478dbf83e117066a636fa61cf5891410 236 Pfam PF02734 DAK2 domain 32 205 2.4E-52 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_07160 478dbf83e117066a636fa61cf5891410 236 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 14 205 4.5E-68 T 12-10-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00561+2.7.1.121 UA74_07160 478dbf83e117066a636fa61cf5891410 236 SMART SM01120 32 206 5.0E-69 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_07160 478dbf83e117066a636fa61cf5891410 236 SUPERFAMILY SSF101473 9 205 4.71E-50 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_15055 3977fe520b38d96ebf491383cd4d4e63 209 Gene3D G3DSA:1.10.357.10 14 208 6.9E-52 T 12-10-2018 UA74_15055 3977fe520b38d96ebf491383cd4d4e63 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 76 2.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15055 3977fe520b38d96ebf491383cd4d4e63 209 SUPERFAMILY SSF48498 143 178 1.16E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_15055 3977fe520b38d96ebf491383cd4d4e63 209 SUPERFAMILY SSF46689 24 90 1.25E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_07970 3dab9ba824bfe60e5da7a9af459ce22b 265 Gene3D G3DSA:3.90.1560.10 37 261 2.0E-38 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 UA74_07970 3dab9ba824bfe60e5da7a9af459ce22b 265 Pfam PF04029 2-phosphosulpholactate phosphatase 43 255 1.0E-18 T 12-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 UA74_07970 3dab9ba824bfe60e5da7a9af459ce22b 265 SUPERFAMILY SSF142823 27 258 4.45E-39 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 UA74_15235 9627fd8bd438e1b84c3e1b962c6e285f 199 SUPERFAMILY SSF55729 43 188 7.55E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_15235 9627fd8bd438e1b84c3e1b962c6e285f 199 Pfam PF00583 Acetyltransferase (GNAT) family 69 167 2.8E-12 T 12-10-2018 IPR000182 GNAT domain UA74_15235 9627fd8bd438e1b84c3e1b962c6e285f 199 Gene3D G3DSA:3.40.630.30 41 193 1.4E-40 T 12-10-2018 UA74_01840 575d5f681a0c95e0d5193e02538ee74b 130 Gene3D G3DSA:2.60.120.10 1 115 2.0E-43 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_01840 575d5f681a0c95e0d5193e02538ee74b 130 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 36.852 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 UA74_01840 575d5f681a0c95e0d5193e02538ee74b 130 Pfam PF06339 Ectoine synthase 2 125 1.7E-56 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 UA74_01840 575d5f681a0c95e0d5193e02538ee74b 130 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 7.0E-39 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 UA74_01840 575d5f681a0c95e0d5193e02538ee74b 130 SUPERFAMILY SSF51182 13 125 1.17E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_16075 168b8b3aa47c74f266df40fdc436bfcc 194 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 36 190 8.7E-25 T 12-10-2018 IPR000160 GGDEF domain UA74_16075 168b8b3aa47c74f266df40fdc436bfcc 194 SMART SM00267 25 192 3.1E-23 T 12-10-2018 IPR000160 GGDEF domain UA74_16075 168b8b3aa47c74f266df40fdc436bfcc 194 Pfam PF00990 Diguanylate cyclase, GGDEF domain 37 187 7.5E-25 T 12-10-2018 IPR000160 GGDEF domain UA74_16075 168b8b3aa47c74f266df40fdc436bfcc 194 SUPERFAMILY SSF55073 40 191 6.12E-27 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_16075 168b8b3aa47c74f266df40fdc436bfcc 194 Gene3D G3DSA:3.30.70.270 37 193 2.3E-32 T 12-10-2018 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 16 626 4.3E-269 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 SUPERFAMILY SSF52540 13 234 6.27E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 Pfam PF03144 Elongation factor Tu domain 2 247 317 2.8E-12 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:2.40.30.10 227 327 7.4E-30 T 12-10-2018 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 SUPERFAMILY SSF54980 427 541 2.25E-27 T 12-10-2018 IPR035647 EF-G domain III/V-like UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:3.30.70.870 335 618 3.7E-115 T 12-10-2018 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 86 96 3.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 18 31 3.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 138 147 3.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 PRINTS PR00315 GTP-binding elongation factor signature 102 113 3.6E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 160 6.5E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 Pfam PF00009 Elongation factor Tu GTP binding domain 16 223 1.6E-50 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 SUPERFAMILY SSF54980 330 416 1.25E-10 T 12-10-2018 IPR035647 EF-G domain III/V-like UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 SMART SM00838 424 512 0.0033 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:3.30.70.240 418 510 3.7E-115 T 12-10-2018 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:3.40.50.300 14 226 8.3E-55 T 12-10-2018 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 Gene3D G3DSA:2.40.50.250 511 626 3.7E-115 T 12-10-2018 UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 Pfam PF00679 Elongation factor G C-terminus 425 508 1.5E-21 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like UA74_04360 4710cfba64ded89f7ef5da45b1d8a9b9 637 SUPERFAMILY SSF50447 180 328 4.57E-31 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_08985 ee0d9a2540ace8687a88600726639b0f 408 Pfam PF08402 TOBE domain 307 392 5.6E-14 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 UA74_08985 ee0d9a2540ace8687a88600726639b0f 408 SMART SM00382 48 239 5.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_08985 ee0d9a2540ace8687a88600726639b0f 408 SUPERFAMILY SSF50331 262 391 3.1E-17 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UA74_08985 ee0d9a2540ace8687a88600726639b0f 408 Gene3D G3DSA:3.40.50.300 17 258 4.7E-72 T 12-10-2018 UA74_08985 ee0d9a2540ace8687a88600726639b0f 408 Pfam PF00005 ABC transporter 39 181 5.7E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_08985 ee0d9a2540ace8687a88600726639b0f 408 SUPERFAMILY SSF52540 24 257 5.59E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08985 ee0d9a2540ace8687a88600726639b0f 408 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_29960 49547537de501e07100cf5d3d0bc5ba6 363 Gene3D G3DSA:3.30.360.10 194 303 2.5E-149 T 12-10-2018 UA74_29960 49547537de501e07100cf5d3d0bc5ba6 363 Gene3D G3DSA:3.40.50.720 8 356 2.5E-149 T 12-10-2018 UA74_29960 49547537de501e07100cf5d3d0bc5ba6 363 PIRSF PIRSF015578 2 359 1.4E-93 T 12-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_29960 49547537de501e07100cf5d3d0bc5ba6 363 SUPERFAMILY SSF51735 7 359 1.41E-93 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_29960 49547537de501e07100cf5d3d0bc5ba6 363 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 8 357 1.3E-207 T 12-10-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria UA74_29960 49547537de501e07100cf5d3d0bc5ba6 363 Pfam PF01658 Myo-inositol-1-phosphate synthase 195 303 2.1E-31 T 12-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 UA74_29960 49547537de501e07100cf5d3d0bc5ba6 363 SUPERFAMILY SSF55347 194 302 1.57E-34 T 12-10-2018 UA74_07200 619edbb3ceae57ad07263c8abe0f25b9 321 Gene3D G3DSA:3.40.50.300 46 257 1.8E-85 T 12-10-2018 UA74_07200 619edbb3ceae57ad07263c8abe0f25b9 321 SMART SM00382 49 307 0.0034 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_07200 619edbb3ceae57ad07263c8abe0f25b9 321 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 315 3.5E-101 T 12-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_07200 619edbb3ceae57ad07263c8abe0f25b9 321 SUPERFAMILY SSF52540 3 314 5.7E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07200 619edbb3ceae57ad07263c8abe0f25b9 321 Pfam PF03308 ArgK protein 22 283 4.4E-97 T 12-10-2018 UA74_09985 c820d0bffda3cd54bb5b0dea739040f4 65 Pfam PF04149 Domain of unknown function (DUF397) 9 60 7.9E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_16750 4265d4c8205ff04c8adf087c4de11642 354 Gene3D G3DSA:1.10.10.60 237 352 7.3E-24 T 12-10-2018 UA74_16750 4265d4c8205ff04c8adf087c4de11642 354 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 33 214 2.2E-37 T 12-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal UA74_16750 4265d4c8205ff04c8adf087c4de11642 354 Pfam PF12833 Helix-turn-helix domain 264 341 3.4E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_16750 4265d4c8205ff04c8adf087c4de11642 354 SMART SM00342 257 339 9.8E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_16750 4265d4c8205ff04c8adf087c4de11642 354 SUPERFAMILY SSF46689 292 342 1.48E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_28960 17ac9521fc29e26887582fe5d4837b09 193 SUPERFAMILY SSF55811 13 183 5.69E-35 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_28960 17ac9521fc29e26887582fe5d4837b09 193 Pfam PF00293 NUDIX domain 52 160 2.2E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_28960 17ac9521fc29e26887582fe5d4837b09 193 Gene3D G3DSA:3.90.79.10 9 190 4.0E-42 T 12-10-2018 UA74_28960 17ac9521fc29e26887582fe5d4837b09 193 ProSitePatterns PS00893 Nudix box signature. 84 105 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_11965 16829492fe2622bc5b44211d8ef10fda 348 SUPERFAMILY SSF49384 246 347 3.28E-30 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UA74_11965 16829492fe2622bc5b44211d8ef10fda 348 SUPERFAMILY SSF81296 32 224 8.26E-45 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_11965 16829492fe2622bc5b44211d8ef10fda 348 Gene3D G3DSA:2.70.50.50 32 226 1.5E-66 T 12-10-2018 UA74_11965 16829492fe2622bc5b44211d8ef10fda 348 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 221 4.0E-42 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal UA74_11965 16829492fe2622bc5b44211d8ef10fda 348 Gene3D G3DSA:2.60.40.290 244 348 6.2E-32 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 UA74_11965 16829492fe2622bc5b44211d8ef10fda 348 SMART SM00637 247 347 1.2E-37 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_11965 16829492fe2622bc5b44211d8ef10fda 348 Pfam PF00553 Cellulose binding domain 247 347 1.4E-28 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_11160 1c586ab8634ec2a7f4a3cb71ad77496e 143 SUPERFAMILY SSF46906 69 141 1.57E-20 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily UA74_11160 1c586ab8634ec2a7f4a3cb71ad77496e 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 43 74 0.001 T 12-10-2018 UA74_11160 1c586ab8634ec2a7f4a3cb71ad77496e 143 Gene3D G3DSA:1.10.10.2720 74 143 1.6E-24 T 12-10-2018 UA74_11160 1c586ab8634ec2a7f4a3cb71ad77496e 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 141 3.1E-23 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_11160 1c586ab8634ec2a7f4a3cb71ad77496e 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 13 67 1.8E-9 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal UA74_11160 1c586ab8634ec2a7f4a3cb71ad77496e 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 7 143 21.562 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 UA74_11160 1c586ab8634ec2a7f4a3cb71ad77496e 143 SMART SM00649 11 142 3.4E-38 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 UA74_11160 1c586ab8634ec2a7f4a3cb71ad77496e 143 SUPERFAMILY SSF54747 13 85 5.23E-11 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily UA74_11160 1c586ab8634ec2a7f4a3cb71ad77496e 143 Gene3D G3DSA:3.30.1550.10 6 73 5.6E-12 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily UA74_11450 9b5cbf359bfcf2b6fee66f4bd69b4d0e 316 SUPERFAMILY SSF56235 44 306 1.56E-17 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_11450 9b5cbf359bfcf2b6fee66f4bd69b4d0e 316 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 307 37.598 T 12-10-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 KEGG: 00340+3.5.1.118|MetaCyc: PWY-7255 UA74_11450 9b5cbf359bfcf2b6fee66f4bd69b4d0e 316 Gene3D G3DSA:3.60.20.10 2 71 6.6E-17 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_11450 9b5cbf359bfcf2b6fee66f4bd69b4d0e 316 Gene3D G3DSA:3.60.20.10 91 311 1.7E-56 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_11450 9b5cbf359bfcf2b6fee66f4bd69b4d0e 316 Pfam PF13522 Glutamine amidotransferase domain 135 278 5.7E-13 T 12-10-2018 UA74_01770 b08fd3386208f83dbeaddb2f4c72d210 362 Pfam PF00005 ABC transporter 23 164 2.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_01770 b08fd3386208f83dbeaddb2f4c72d210 362 SUPERFAMILY SSF52540 12 244 1.39E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01770 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.940 225 352 3.1E-26 T 12-10-2018 UA74_01770 b08fd3386208f83dbeaddb2f4c72d210 362 Pfam PF08402 TOBE domain 278 351 1.7E-7 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 UA74_01770 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.140 285 342 3.1E-26 T 12-10-2018 UA74_01770 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:3.40.50.300 9 224 2.5E-60 T 12-10-2018 UA74_01770 b08fd3386208f83dbeaddb2f4c72d210 362 SMART SM00382 31 214 8.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01770 b08fd3386208f83dbeaddb2f4c72d210 362 SUPERFAMILY SSF50331 239 359 3.64E-23 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UA74_01770 b08fd3386208f83dbeaddb2f4c72d210 362 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_23550 b08fd3386208f83dbeaddb2f4c72d210 362 Pfam PF00005 ABC transporter 23 164 2.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_23550 b08fd3386208f83dbeaddb2f4c72d210 362 SUPERFAMILY SSF52540 12 244 1.39E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_23550 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.940 225 352 3.1E-26 T 12-10-2018 UA74_23550 b08fd3386208f83dbeaddb2f4c72d210 362 Pfam PF08402 TOBE domain 278 351 1.7E-7 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 UA74_23550 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:2.40.50.140 285 342 3.1E-26 T 12-10-2018 UA74_23550 b08fd3386208f83dbeaddb2f4c72d210 362 Gene3D G3DSA:3.40.50.300 9 224 2.5E-60 T 12-10-2018 UA74_23550 b08fd3386208f83dbeaddb2f4c72d210 362 SMART SM00382 31 214 8.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_23550 b08fd3386208f83dbeaddb2f4c72d210 362 SUPERFAMILY SSF50331 239 359 3.64E-23 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UA74_23550 b08fd3386208f83dbeaddb2f4c72d210 362 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_03840 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 Gene3D G3DSA:3.40.47.10 2 405 6.0E-130 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_03840 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 2.3E-134 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_03840 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 SUPERFAMILY SSF53901 283 404 8.89E-44 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_03840 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 UA74_03840 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 PIRSF PIRSF000429 1 406 1.7E-124 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_03840 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 Pfam PF02803 Thiolase, C-terminal domain 283 404 2.9E-47 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UA74_03840 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 2.1E-57 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UA74_03840 ae0fc3c266c9f1cd72ff3e6efcbaa0ff 406 SUPERFAMILY SSF53901 3 281 9.02E-65 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_06465 7ee36d806a7b15c469629a8e04080a05 87 Gene3D G3DSA:1.10.1200.10 2 87 1.3E-12 T 12-10-2018 IPR036736 ACP-like superfamily UA74_06465 7ee36d806a7b15c469629a8e04080a05 87 SUPERFAMILY SSF47336 3 80 9.95E-12 T 12-10-2018 IPR036736 ACP-like superfamily UA74_06465 7ee36d806a7b15c469629a8e04080a05 87 Pfam PF00550 Phosphopantetheine attachment site 8 73 3.1E-6 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_15930 dd1fb7c790650214431640cf7ed9397e 1025 Gene3D G3DSA:3.40.50.300 446 691 1.1E-25 T 12-10-2018 UA74_15930 dd1fb7c790650214431640cf7ed9397e 1025 Gene3D G3DSA:3.90.1570.50 102 252 1.0E-13 T 12-10-2018 UA74_15930 dd1fb7c790650214431640cf7ed9397e 1025 Pfam PF04851 Type III restriction enzyme, res subunit 261 420 3.1E-14 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_15930 dd1fb7c790650214431640cf7ed9397e 1025 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 8 686 7.7E-119 T 12-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 UA74_15930 dd1fb7c790650214431640cf7ed9397e 1025 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 11 202 8.6E-21 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 UA74_15930 dd1fb7c790650214431640cf7ed9397e 1025 SMART SM00487 257 448 2.3E-15 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_15930 dd1fb7c790650214431640cf7ed9397e 1025 Gene3D G3DSA:3.40.50.300 261 445 6.9E-35 T 12-10-2018 UA74_15930 dd1fb7c790650214431640cf7ed9397e 1025 SUPERFAMILY SSF52540 232 459 2.13E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13880 6ca5a3d92ce921a767c63b06d882919b 474 SUPERFAMILY SSF47413 7 66 2.15E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_13880 6ca5a3d92ce921a767c63b06d882919b 474 SMART SM00530 8 63 2.1E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_13880 6ca5a3d92ce921a767c63b06d882919b 474 Pfam PF13560 Helix-turn-helix domain 7 66 6.9E-10 T 12-10-2018 UA74_13880 6ca5a3d92ce921a767c63b06d882919b 474 Gene3D G3DSA:1.10.260.40 4 63 2.9E-13 T 12-10-2018 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 453 1.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 467 1.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 511 1.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 492 1.6E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 SUPERFAMILY SSF55874 347 518 7.33E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 SUPERFAMILY SSF47384 273 357 2.75E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 Pfam PF00672 HAMP domain 230 279 1.2E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 Gene3D G3DSA:1.20.1480.50 197 284 2.9E-15 T 12-10-2018 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 SMART SM00304 230 282 2.8E-15 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 SUPERFAMILY SSF158472 230 281 3.27E-10 T 12-10-2018 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 SMART SM00388 290 357 2.4E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 Gene3D G3DSA:1.10.287.130 285 361 1.5E-15 T 12-10-2018 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 404 512 4.4E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 Pfam PF00512 His Kinase A (phospho-acceptor) domain 291 357 5.0E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 Gene3D G3DSA:3.30.565.10 362 513 1.8E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_26535 6bb9c94ebd515ac6c18feb3beb1047d1 654 SMART SM00387 403 514 1.0E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_01025 77e9e42ca62f4cedbbe443d1250923b1 110 SUPERFAMILY SSF82607 1 85 3.01E-25 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_01025 77e9e42ca62f4cedbbe443d1250923b1 110 Pfam PF02575 YbaB/EbfC DNA-binding family 1 84 7.6E-31 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_01025 77e9e42ca62f4cedbbe443d1250923b1 110 PIRSF PIRSF004555 1 99 1.0E-28 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_01025 77e9e42ca62f4cedbbe443d1250923b1 110 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 77 3.0E-19 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_01025 77e9e42ca62f4cedbbe443d1250923b1 110 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 83 17.476 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_01025 77e9e42ca62f4cedbbe443d1250923b1 110 Gene3D G3DSA:3.30.1310.10 1 93 5.2E-31 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_28925 a7ddb29229ee19215fbfb09d1de450ac 168 Gene3D G3DSA:1.10.10.10 10 149 1.4E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28925 a7ddb29229ee19215fbfb09d1de450ac 168 SMART SM00347 32 131 3.6E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28925 a7ddb29229ee19215fbfb09d1de450ac 168 Pfam PF01047 MarR family 39 98 1.5E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28925 a7ddb29229ee19215fbfb09d1de450ac 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28925 a7ddb29229ee19215fbfb09d1de450ac 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28925 a7ddb29229ee19215fbfb09d1de450ac 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.7E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28925 a7ddb29229ee19215fbfb09d1de450ac 168 SUPERFAMILY SSF46785 15 143 1.91E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_30185 f1cf6dc8eb8135298762a9b80ba6bd59 242 SUPERFAMILY SSF48498 91 234 2.2E-16 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_30185 f1cf6dc8eb8135298762a9b80ba6bd59 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_30185 f1cf6dc8eb8135298762a9b80ba6bd59 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_30185 f1cf6dc8eb8135298762a9b80ba6bd59 242 SUPERFAMILY SSF46689 6 79 2.89E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_30185 f1cf6dc8eb8135298762a9b80ba6bd59 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 3.8E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_30185 f1cf6dc8eb8135298762a9b80ba6bd59 242 Gene3D G3DSA:1.10.357.10 1 239 6.1E-59 T 12-10-2018 UA74_29680 067650214c494f9bbd52082290fc5583 635 Gene3D G3DSA:2.40.10.500 187 284 3.0E-7 T 12-10-2018 UA74_29680 067650214c494f9bbd52082290fc5583 635 SUPERFAMILY SSF101898 184 492 1.41E-28 T 12-10-2018 UA74_29680 067650214c494f9bbd52082290fc5583 635 SUPERFAMILY SSF52833 30 193 4.55E-30 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_29680 067650214c494f9bbd52082290fc5583 635 Pfam PF00578 AhpC/TSA family 29 149 1.5E-8 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_29680 067650214c494f9bbd52082290fc5583 635 Gene3D G3DSA:3.40.30.10 15 180 8.0E-33 T 12-10-2018 UA74_29680 067650214c494f9bbd52082290fc5583 635 Gene3D G3DSA:2.120.10.30 325 456 1.8E-21 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_09400 05864684bedff8970034a8617d69f8c7 751 Pfam PF03725 3' exoribonuclease family, domain 2 487 561 1.7E-5 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_09400 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF54211 11 152 2.83E-45 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_09400 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF54791 586 672 2.18E-17 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 UA74_09400 05864684bedff8970034a8617d69f8c7 751 Gene3D G3DSA:3.30.230.70 261 581 5.8E-103 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_09400 05864684bedff8970034a8617d69f8c7 751 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 18 722 9.7E-264 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_09400 05864684bedff8970034a8617d69f8c7 751 Pfam PF01138 3' exoribonuclease family, domain 1 21 152 1.2E-16 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_09400 05864684bedff8970034a8617d69f8c7 751 Pfam PF01138 3' exoribonuclease family, domain 1 352 484 8.6E-15 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_09400 05864684bedff8970034a8617d69f8c7 751 Gene3D G3DSA:2.40.50.140 582 706 2.0E-46 T 12-10-2018 UA74_09400 05864684bedff8970034a8617d69f8c7 751 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 269 347 2.5E-18 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_09400 05864684bedff8970034a8617d69f8c7 751 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 6 723 0.0 T 12-10-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_09400 05864684bedff8970034a8617d69f8c7 751 SMART SM00322 583 648 1.8E-10 T 12-10-2018 IPR004087 K Homology domain GO:0003676 UA74_09400 05864684bedff8970034a8617d69f8c7 751 Pfam PF00013 KH domain 587 644 5.2E-10 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 UA74_09400 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF55666 478 577 3.11E-24 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_09400 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF46915 264 349 2.43E-15 T 12-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_09400 05864684bedff8970034a8617d69f8c7 751 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 10 727 27.002 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_09400 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF55666 153 259 6.71E-27 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_09400 05864684bedff8970034a8617d69f8c7 751 SMART SM00316 653 724 7.2E-16 T 12-10-2018 IPR022967 RNA-binding domain, S1 UA74_09400 05864684bedff8970034a8617d69f8c7 751 Pfam PF00575 S1 RNA binding domain 652 721 1.6E-13 T 12-10-2018 IPR003029 S1 domain GO:0003676 UA74_09400 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF50249 653 721 1.64E-14 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_09400 05864684bedff8970034a8617d69f8c7 751 PIRSF PIRSF005499 8 750 2.9E-282 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UA74_09400 05864684bedff8970034a8617d69f8c7 751 SUPERFAMILY SSF54211 323 519 1.97E-42 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_09400 05864684bedff8970034a8617d69f8c7 751 Gene3D G3DSA:3.30.230.70 5 250 5.6E-83 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site UA74_02935 e77a62862c007231daf98dc062cea8bf 397 SUPERFAMILY SSF50447 207 304 4.78E-30 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_02935 e77a62862c007231daf98dc062cea8bf 397 Gene3D G3DSA:2.40.30.10 208 337 2.9E-52 T 12-10-2018 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 Pfam PF03143 Elongation factor Tu C-terminal domain 303 395 1.1E-31 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal UA74_02935 e77a62862c007231daf98dc062cea8bf 397 Gene3D G3DSA:3.40.50.300 1 205 1.5E-68 T 12-10-2018 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 395 2.3E-217 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 9.9E-13 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 SUPERFAMILY SSF50465 305 397 6.04E-35 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal UA74_02935 e77a62862c007231daf98dc062cea8bf 397 Pfam PF03144 Elongation factor Tu domain 2 227 297 1.7E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 Gene3D G3DSA:2.40.30.10 341 395 2.5E-25 T 12-10-2018 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.3E-57 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02935 e77a62862c007231daf98dc062cea8bf 397 SUPERFAMILY SSF52540 6 221 2.78E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_02935 e77a62862c007231daf98dc062cea8bf 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 58.189 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 SMART SM00304 86 139 2.1E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 SMART SM00387 246 360 1.5E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 SUPERFAMILY SSF55874 206 360 7.2E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 SMART SM00388 140 204 3.1E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 Gene3D G3DSA:3.30.565.10 204 359 2.5E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 338 4.8E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 4.8E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 357 4.8E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 SUPERFAMILY SSF158472 88 136 1.31E-6 T 12-10-2018 UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 SUPERFAMILY SSF47384 123 203 1.96E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 203 3.6E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 250 358 9.4E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_19195 f11c074f7807201e217400bff7e7f8bd 369 Gene3D G3DSA:1.10.287.130 90 203 6.0E-24 T 12-10-2018 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 Gene3D G3DSA:3.40.50.150 203 487 4.8E-65 T 12-10-2018 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 Pfam PF01420 Type I restriction modification DNA specificity domain 597 719 2.3E-11 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 Pfam PF02384 N-6 DNA Methylase 206 500 2.2E-63 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 SUPERFAMILY SSF53335 107 521 7.13E-74 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 SUPERFAMILY SSF116734 550 733 1.64E-28 T 12-10-2018 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 313 319 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 Gene3D G3DSA:3.90.220.20 548 735 3.3E-32 T 12-10-2018 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 245 259 5.7E-20 T 12-10-2018 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 310 322 5.7E-20 T 12-10-2018 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 341 365 5.7E-20 T 12-10-2018 UA74_15910 ac5ef3054eeba526fd72f2de717318a8 743 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 221 237 5.7E-20 T 12-10-2018 UA74_14440 7d1b35399e34107b83f7bb66bca04eae 242 SUPERFAMILY SSF56214 113 228 7.32E-15 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_14440 7d1b35399e34107b83f7bb66bca04eae 242 PRINTS PR01399 Enterobactin synthetase component D signature 158 174 4.0E-24 T 12-10-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UA74_14440 7d1b35399e34107b83f7bb66bca04eae 242 PRINTS PR01399 Enterobactin synthetase component D signature 51 71 4.0E-24 T 12-10-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UA74_14440 7d1b35399e34107b83f7bb66bca04eae 242 PRINTS PR01399 Enterobactin synthetase component D signature 81 99 4.0E-24 T 12-10-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UA74_14440 7d1b35399e34107b83f7bb66bca04eae 242 Gene3D G3DSA:3.90.470.20 35 128 3.0E-5 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_14440 7d1b35399e34107b83f7bb66bca04eae 242 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 115 191 1.4E-9 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_00645 c7bf705ad00848938da09cd512b40767 310 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 3.0E-59 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_00645 c7bf705ad00848938da09cd512b40767 310 Gene3D G3DSA:3.90.25.10 178 306 8.2E-98 T 12-10-2018 UA74_00645 c7bf705ad00848938da09cd512b40767 310 Gene3D G3DSA:3.40.50.720 3 241 8.2E-98 T 12-10-2018 UA74_00645 c7bf705ad00848938da09cd512b40767 310 SUPERFAMILY SSF51735 1 309 2.78E-87 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_10515 0a4176eebd033966e4bb6b5072067ac0 153 PRINTS PR01438 Universal stress protein signature 5 23 1.6E-10 T 12-10-2018 IPR006015 Universal stress protein A UA74_10515 0a4176eebd033966e4bb6b5072067ac0 153 PRINTS PR01438 Universal stress protein signature 118 140 1.6E-10 T 12-10-2018 IPR006015 Universal stress protein A UA74_10515 0a4176eebd033966e4bb6b5072067ac0 153 PRINTS PR01438 Universal stress protein signature 100 112 1.6E-10 T 12-10-2018 IPR006015 Universal stress protein A UA74_10515 0a4176eebd033966e4bb6b5072067ac0 153 Gene3D G3DSA:3.40.50.620 2 147 6.7E-37 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_10515 0a4176eebd033966e4bb6b5072067ac0 153 SUPERFAMILY SSF52402 7 143 8.37E-30 T 12-10-2018 UA74_10515 0a4176eebd033966e4bb6b5072067ac0 153 Pfam PF00582 Universal stress protein family 4 140 1.4E-23 T 12-10-2018 IPR006016 UspA UA74_28995 06df0b90775c7aa77e74fec747825d09 740 Gene3D G3DSA:3.40.50.300 318 604 1.7E-36 T 12-10-2018 UA74_28995 06df0b90775c7aa77e74fec747825d09 740 SUPERFAMILY SSF52540 306 569 1.33E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28995 06df0b90775c7aa77e74fec747825d09 740 Pfam PF01580 FtsK/SpoIIIE family 369 538 2.3E-7 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_13805 4332d6e2a9a4c93c5d29757ce08478a5 251 SUPERFAMILY SSF46955 4 105 5.86E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_13805 4332d6e2a9a4c93c5d29757ce08478a5 251 Gene3D G3DSA:1.10.1660.10 6 236 2.3E-27 T 12-10-2018 UA74_13805 4332d6e2a9a4c93c5d29757ce08478a5 251 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.6E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13805 4332d6e2a9a4c93c5d29757ce08478a5 251 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.6E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13805 4332d6e2a9a4c93c5d29757ce08478a5 251 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.6E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13805 4332d6e2a9a4c93c5d29757ce08478a5 251 Pfam PF13411 MerR HTH family regulatory protein 4 68 1.9E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13805 4332d6e2a9a4c93c5d29757ce08478a5 251 SMART SM00422 3 72 2.0E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_01700 c38eb18bf6559ddd98920616a7a506d1 477 PIRSF PIRSF500217 1 477 8.5E-150 T 12-10-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 UA74_01700 c38eb18bf6559ddd98920616a7a506d1 477 PIRSF PIRSF016636 1 477 1.1E-147 T 12-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB UA74_01700 c38eb18bf6559ddd98920616a7a506d1 477 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 152 356 8.3E-33 T 12-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT UA74_27595 e031c84732409f177cc1a818773ece03 288 SUPERFAMILY SSF51735 125 283 4.67E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_27595 e031c84732409f177cc1a818773ece03 288 Gene3D G3DSA:3.40.50.720 9 261 1.5E-104 T 12-10-2018 UA74_27595 e031c84732409f177cc1a818773ece03 288 SUPERFAMILY SSF53223 5 124 1.25E-32 T 12-10-2018 UA74_27595 e031c84732409f177cc1a818773ece03 288 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 126 284 3.0E-61 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_27595 e031c84732409f177cc1a818773ece03 288 Hamap MF_01576 Bifunctional protein FolD [folD]. 6 285 36.038 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_27595 e031c84732409f177cc1a818773ece03 288 Gene3D G3DSA:3.40.50.10860 11 279 1.5E-104 T 12-10-2018 UA74_27595 e031c84732409f177cc1a818773ece03 288 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 8 123 6.2E-31 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_27595 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 157 177 2.2E-63 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_27595 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 208 237 2.2E-63 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_27595 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 112 133 2.2E-63 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_27595 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 258 276 2.2E-63 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_27595 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 77 104 2.2E-63 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_27595 e031c84732409f177cc1a818773ece03 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 36 58 2.2E-63 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_03900 289050199fee1806ec00c1cfc21d7b90 368 PIRSF PIRSF026534 60 368 3.7E-96 T 12-10-2018 IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase GO:0046558 UA74_03900 289050199fee1806ec00c1cfc21d7b90 368 Pfam PF04616 Glycosyl hydrolases family 43 85 365 4.0E-54 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_03900 289050199fee1806ec00c1cfc21d7b90 368 SUPERFAMILY SSF75005 73 367 7.42E-73 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_03900 289050199fee1806ec00c1cfc21d7b90 368 Gene3D G3DSA:2.115.10.20 72 367 6.4E-87 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_26660 f717905b64fa984df75b23103df9f0de 377 SUPERFAMILY SSF53756 8 362 7.14E-65 T 12-10-2018 UA74_26660 f717905b64fa984df75b23103df9f0de 377 Pfam PF13439 Glycosyltransferase Family 4 16 172 1.0E-9 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_26660 f717905b64fa984df75b23103df9f0de 377 Gene3D G3DSA:3.40.50.2000 13 362 4.0E-56 T 12-10-2018 UA74_26660 f717905b64fa984df75b23103df9f0de 377 Pfam PF00534 Glycosyl transferases group 1 195 349 1.3E-27 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_26660 f717905b64fa984df75b23103df9f0de 377 Gene3D G3DSA:3.40.50.2000 171 350 4.0E-56 T 12-10-2018 UA74_23755 a61ded0c2e3f8f85c857809ec62f4f71 625 SUPERFAMILY SSF56519 139 324 2.75E-24 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 UA74_23755 a61ded0c2e3f8f85c857809ec62f4f71 625 Gene3D G3DSA:3.40.710.10 321 625 4.8E-67 T 12-10-2018 UA74_23755 a61ded0c2e3f8f85c857809ec62f4f71 625 SUPERFAMILY SSF56601 280 619 4.73E-67 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_23755 a61ded0c2e3f8f85c857809ec62f4f71 625 Gene3D G3DSA:3.90.1310.30 138 320 6.5E-20 T 12-10-2018 UA74_23755 a61ded0c2e3f8f85c857809ec62f4f71 625 Pfam PF03717 Penicillin-binding Protein dimerisation domain 145 302 3.1E-16 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UA74_23755 a61ded0c2e3f8f85c857809ec62f4f71 625 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 30 137 3.6E-11 T 12-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 UA74_23755 a61ded0c2e3f8f85c857809ec62f4f71 625 Pfam PF00905 Penicillin binding protein transpeptidase domain 346 615 6.3E-43 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_19925 5ec002a476194a3c5c566af05c2c1f36 393 Gene3D G3DSA:3.40.710.10 39 369 8.0E-101 T 12-10-2018 UA74_19925 5ec002a476194a3c5c566af05c2c1f36 393 SUPERFAMILY SSF56601 43 363 2.29E-74 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_19925 5ec002a476194a3c5c566af05c2c1f36 393 Pfam PF00144 Beta-lactamase 52 364 5.1E-60 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_00435 3c06b6dd8eefbacf6ffef9426db7f3f7 274 Gene3D G3DSA:2.40.50.40 156 223 2.1E-9 T 12-10-2018 UA74_00435 3c06b6dd8eefbacf6ffef9426db7f3f7 274 SUPERFAMILY SSF52172 9 144 5.27E-23 T 12-10-2018 IPR011006 CheY-like superfamily UA74_00435 3c06b6dd8eefbacf6ffef9426db7f3f7 274 Pfam PF04397 LytTr DNA-binding domain 166 262 3.2E-23 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 UA74_00435 3c06b6dd8eefbacf6ffef9426db7f3f7 274 Gene3D G3DSA:3.40.50.2300 6 145 9.5E-23 T 12-10-2018 UA74_00435 3c06b6dd8eefbacf6ffef9426db7f3f7 274 SMART SM00850 164 263 1.2E-28 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 UA74_00435 3c06b6dd8eefbacf6ffef9426db7f3f7 274 Pfam PF00072 Response regulator receiver domain 12 134 1.5E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_00435 3c06b6dd8eefbacf6ffef9426db7f3f7 274 SMART SM00448 10 134 3.3E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_11010 80dfa7c7c24c89dc434bd8b8bf4148ee 86 Gene3D G3DSA:1.10.1200.10 1 83 4.1E-20 T 12-10-2018 IPR036736 ACP-like superfamily UA74_11010 80dfa7c7c24c89dc434bd8b8bf4148ee 86 SMART SM00823 Phosphopantetheine attachment site 6 81 0.0073 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_11010 80dfa7c7c24c89dc434bd8b8bf4148ee 86 SUPERFAMILY SSF47336 2 81 2.75E-14 T 12-10-2018 IPR036736 ACP-like superfamily UA74_11010 80dfa7c7c24c89dc434bd8b8bf4148ee 86 Pfam PF00550 Phosphopantetheine attachment site 7 77 2.9E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_11330 24eb27d25899b2198a724ff9ac7fea27 209 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 1.8E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_11330 24eb27d25899b2198a724ff9ac7fea27 209 Gene3D G3DSA:3.60.15.10 18 206 1.5E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_11330 24eb27d25899b2198a724ff9ac7fea27 209 SUPERFAMILY SSF56281 21 201 5.46E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_11330 24eb27d25899b2198a724ff9ac7fea27 209 SMART SM00849 24 188 3.1E-34 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_14745 e30bd321f3bcef87066a90c96a99fd27 337 SUPERFAMILY SSF56349 17 319 3.83E-35 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_14745 e30bd321f3bcef87066a90c96a99fd27 337 Gene3D G3DSA:1.10.150.130 21 114 2.0E-7 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_14745 e30bd321f3bcef87066a90c96a99fd27 337 Pfam PF00589 Phage integrase family 151 310 3.5E-19 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_14745 e30bd321f3bcef87066a90c96a99fd27 337 Gene3D G3DSA:1.10.443.10 132 318 3.2E-31 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_16555 93aa87afd575392b1c156c668b989cf7 492 SMART SM00829 90 456 1.1E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_16555 93aa87afd575392b1c156c668b989cf7 492 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 109 231 1.4E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_16555 93aa87afd575392b1c156c668b989cf7 492 SUPERFAMILY SSF51735 236 425 2.38E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16555 93aa87afd575392b1c156c668b989cf7 492 Pfam PF00107 Zinc-binding dehydrogenase 277 421 1.8E-30 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_16555 93aa87afd575392b1c156c668b989cf7 492 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 76 469 9.8E-173 T 12-10-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 UA74_16555 93aa87afd575392b1c156c668b989cf7 492 Gene3D G3DSA:3.90.180.10 59 481 1.5E-223 T 12-10-2018 UA74_16555 93aa87afd575392b1c156c668b989cf7 492 Gene3D G3DSA:3.40.50.720 260 406 1.5E-223 T 12-10-2018 UA74_16555 93aa87afd575392b1c156c668b989cf7 492 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 266 287 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_16555 93aa87afd575392b1c156c668b989cf7 492 SUPERFAMILY SSF50129 93 271 9.12E-29 T 12-10-2018 IPR011032 GroES-like superfamily UA74_00825 7b42e30726907dbe663fa99d5bee2f19 417 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 381 413 5.4E-4 T 12-10-2018 UA74_00825 7b42e30726907dbe663fa99d5bee2f19 417 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 113 159 6.8E-13 T 12-10-2018 IPR023849 Uncharacterised domain CHP03934, TQXA UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 Pfam PF00072 Response regulator receiver domain 5 119 1.1E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.2E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.2E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.2E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 SUPERFAMILY SSF46894 145 214 5.1E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 SMART SM00448 3 118 9.5E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 SMART SM00421 152 209 4.0E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 Gene3D G3DSA:3.40.50.12740 3 215 3.3E-65 T 12-10-2018 UA74_29510 df04aaae5ee90a9517f6b6208637c5e8 218 SUPERFAMILY SSF52172 1 134 8.4E-32 T 12-10-2018 IPR011006 CheY-like superfamily UA74_28140 e674d47adbe33d12a3cc77d15bd51eb3 154 Gene3D G3DSA:2.30.110.10 12 143 6.1E-35 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_28140 e674d47adbe33d12a3cc77d15bd51eb3 154 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 141 3.0E-37 T 12-10-2018 IPR019920 F420-binding domain, putative UA74_28140 e674d47adbe33d12a3cc77d15bd51eb3 154 SUPERFAMILY SSF50475 15 140 3.37E-29 T 12-10-2018 UA74_28140 e674d47adbe33d12a3cc77d15bd51eb3 154 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 96 3.5E-13 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_27135 73538c649b191fbe54fa7dd0864b866c 245 Gene3D G3DSA:3.40.50.300 2 240 4.8E-65 T 12-10-2018 UA74_27135 73538c649b191fbe54fa7dd0864b866c 245 Pfam PF00005 ABC transporter 24 161 5.6E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_27135 73538c649b191fbe54fa7dd0864b866c 245 SMART SM00382 32 209 2.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_27135 73538c649b191fbe54fa7dd0864b866c 245 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_27135 73538c649b191fbe54fa7dd0864b866c 245 SUPERFAMILY SSF52540 4 222 9.52E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 Gene3D G3DSA:3.40.50.300 268 428 5.3E-26 T 12-10-2018 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 93 1.9E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 Gene3D G3DSA:1.10.10.10 1 95 5.3E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SUPERFAMILY SSF52540 270 539 1.51E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SMART SM00862 17 93 4.8E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 Pfam PF13424 Tetratricopeptide repeat 847 916 2.1E-8 T 12-10-2018 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 Pfam PF13424 Tetratricopeptide repeat 765 832 9.2E-10 T 12-10-2018 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 Gene3D G3DSA:1.25.40.10 656 928 2.1E-47 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SUPERFAMILY SSF46894 4 93 1.79E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 Pfam PF03704 Bacterial transcriptional activator domain 100 245 2.7E-39 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SUPERFAMILY SSF48452 823 923 1.78E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SUPERFAMILY SSF48452 693 851 5.56E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SMART SM01043 100 245 3.0E-47 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 Gene3D G3DSA:1.25.40.10 98 267 1.8E-45 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 Pfam PF00931 NB-ARC domain 303 536 3.5E-13 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SMART SM00028 765 798 55.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SMART SM00028 885 918 39.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SMART SM00028 845 878 290.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SMART SM00028 725 758 0.0099 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SMART SM00028 105 138 78.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SMART SM00028 805 838 8.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 PRINTS PR00364 Disease resistance protein signature 471 485 1.3E-9 T 12-10-2018 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 PRINTS PR00364 Disease resistance protein signature 305 320 1.3E-9 T 12-10-2018 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 PRINTS PR00364 Disease resistance protein signature 386 400 1.3E-9 T 12-10-2018 UA74_18350 ac69f00d4d06fb038c05815485dacbff 947 SUPERFAMILY SSF48452 95 256 4.82E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_27110 988256f1455c0b0cdb27bfad83c3e070 417 Gene3D G3DSA:3.30.420.40 94 389 1.7E-77 T 12-10-2018 UA74_27110 988256f1455c0b0cdb27bfad83c3e070 417 Pfam PF00480 ROK family 88 395 4.1E-46 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_27110 988256f1455c0b0cdb27bfad83c3e070 417 Pfam PF09339 IclR helix-turn-helix domain 20 62 3.2E-5 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_27110 988256f1455c0b0cdb27bfad83c3e070 417 SUPERFAMILY SSF46785 14 75 1.13E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_27110 988256f1455c0b0cdb27bfad83c3e070 417 Gene3D G3DSA:1.10.10.10 4 81 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27110 988256f1455c0b0cdb27bfad83c3e070 417 Gene3D G3DSA:3.30.420.40 214 381 1.7E-77 T 12-10-2018 UA74_27110 988256f1455c0b0cdb27bfad83c3e070 417 SUPERFAMILY SSF53067 88 399 1.2E-42 T 12-10-2018 UA74_29140 81e49e9bd74451c1220d38281a960d8f 151 PIRSF PIRSF030042 14 148 1.7E-9 T 12-10-2018 IPR016942 Uncharacterised conserved protein UCP030042 UA74_29140 81e49e9bd74451c1220d38281a960d8f 151 Pfam PF14340 Domain of unknown function (DUF4395) 12 141 6.0E-39 T 12-10-2018 IPR025508 Domain of unknown function DUF4395 UA74_20745 96f345bcf9e83f27907a18919c28b831 151 Pfam PF04965 Gene 25-like lysozyme 27 116 3.4E-25 T 12-10-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD UA74_20745 96f345bcf9e83f27907a18919c28b831 151 Gene3D G3DSA:3.10.450.40 1 130 3.0E-49 T 12-10-2018 UA74_20745 96f345bcf9e83f27907a18919c28b831 151 SUPERFAMILY SSF160719 22 129 3.53E-34 T 12-10-2018 UA74_07605 e0f65315b375148559d1cd92721f48a4 404 Pfam PF13546 DDE superfamily endonuclease 26 256 8.9E-57 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain UA74_07605 e0f65315b375148559d1cd92721f48a4 404 SUPERFAMILY SSF53098 16 392 1.06E-6 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_23925 e0ebfee6c105136b4cc5710268f7d8c8 415 SUPERFAMILY SSF46785 2 73 5.46E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_23925 e0ebfee6c105136b4cc5710268f7d8c8 415 Gene3D G3DSA:1.10.10.10 273 413 6.2E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23925 e0ebfee6c105136b4cc5710268f7d8c8 415 Pfam PF00196 Bacterial regulatory proteins, luxR family 356 403 4.4E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23925 e0ebfee6c105136b4cc5710268f7d8c8 415 Gene3D G3DSA:1.10.10.10 1 92 5.0E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23925 e0ebfee6c105136b4cc5710268f7d8c8 415 SMART SM00421 346 403 3.2E-4 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23925 e0ebfee6c105136b4cc5710268f7d8c8 415 SUPERFAMILY SSF46894 353 409 1.02E-8 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 759 3.9E-52 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 322 1.1E-11 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SUPERFAMILY SSF52540 159 547 1.07E-94 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 3.2E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 3.2E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 3.2E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 3.2E-41 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:1.10.8.60 766 861 5.0E-28 T 12-10-2018 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:3.40.50.300 159 349 7.2E-71 T 12-10-2018 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:3.40.50.300 552 764 2.6E-84 T 12-10-2018 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 845 7.7E-26 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 851 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SMART SM00382 599 746 1.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SMART SM00382 199 345 1.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SMART SM01086 766 857 5.6E-33 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SUPERFAMILY SSF81923 7 157 6.97E-32 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:3.40.50.300 350 546 1.4E-72 T 12-10-2018 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 4.9E-9 T 12-10-2018 IPR004176 Clp, N-terminal UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 5.9E-14 T 12-10-2018 IPR004176 Clp, N-terminal UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 Gene3D G3DSA:1.10.1780.10 1 151 2.5E-27 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UA74_29600 0fcc9f90c3cf4315d44e9f517d49c7bd 865 SUPERFAMILY SSF52540 548 848 6.81E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08195 cabea79e2b67a3032d3678db54c31441 814 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 381 503 4.3E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_08195 cabea79e2b67a3032d3678db54c31441 814 Gene3D G3DSA:1.10.3720.10 536 796 1.1E-13 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08195 cabea79e2b67a3032d3678db54c31441 814 Gene3D G3DSA:1.10.3720.10 129 233 1.4E-5 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08195 cabea79e2b67a3032d3678db54c31441 814 Gene3D G3DSA:1.10.3720.10 326 511 1.4E-18 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08195 cabea79e2b67a3032d3678db54c31441 814 SUPERFAMILY SSF161098 94 206 7.29E-6 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08195 cabea79e2b67a3032d3678db54c31441 814 SUPERFAMILY SSF161098 380 502 2.09E-15 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08195 cabea79e2b67a3032d3678db54c31441 814 SUPERFAMILY SSF161098 538 806 1.14E-20 T 12-10-2018 IPR035906 MetI-like superfamily UA74_27520 7a643f1d418a45f402dd28d28a301857 385 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 56 322 4.3E-69 T 12-10-2018 IPR005274 Inner membrane protein YhjD UA74_27520 7a643f1d418a45f402dd28d28a301857 385 PIRSF PIRSF035875 39 342 4.1E-31 T 12-10-2018 IPR017039 Virulence factor BrkB UA74_27520 7a643f1d418a45f402dd28d28a301857 385 Pfam PF03631 Virulence factor BrkB 67 323 5.1E-43 T 12-10-2018 IPR017039 Virulence factor BrkB UA74_28885 04409858c06f5832de985eb34465d2df 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 383 2.9E-26 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_28885 04409858c06f5832de985eb34465d2df 391 Gene3D G3DSA:2.40.110.10 134 237 2.4E-35 T 12-10-2018 UA74_28885 04409858c06f5832de985eb34465d2df 391 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 137 149 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_28885 04409858c06f5832de985eb34465d2df 391 SUPERFAMILY SSF47203 241 389 2.26E-38 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_28885 04409858c06f5832de985eb34465d2df 391 Gene3D G3DSA:1.10.540.10 1 132 5.5E-39 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_28885 04409858c06f5832de985eb34465d2df 391 SUPERFAMILY SSF56645 9 236 1.01E-73 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_28885 04409858c06f5832de985eb34465d2df 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 135 224 4.5E-23 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UA74_28885 04409858c06f5832de985eb34465d2df 391 Gene3D G3DSA:1.20.140.10 239 391 5.7E-36 T 12-10-2018 UA74_28885 04409858c06f5832de985eb34465d2df 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 131 3.9E-29 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UA74_13090 ccfe1ab0b9117405fb131d217efebd6c 471 Gene3D G3DSA:3.40.50.2000 293 452 5.2E-42 T 12-10-2018 UA74_13090 ccfe1ab0b9117405fb131d217efebd6c 471 Gene3D G3DSA:3.40.50.2000 34 292 8.6E-31 T 12-10-2018 UA74_13090 ccfe1ab0b9117405fb131d217efebd6c 471 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 304 442 3.8E-9 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 UA74_13090 ccfe1ab0b9117405fb131d217efebd6c 471 SUPERFAMILY SSF53756 44 468 2.2E-68 T 12-10-2018 UA74_29675 4a51edc0e8b02f93563c5baad080c2b9 448 SUPERFAMILY SSF48208 72 343 3.57E-23 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_29675 4a51edc0e8b02f93563c5baad080c2b9 448 Gene3D G3DSA:1.50.10.20 59 437 9.5E-78 T 12-10-2018 UA74_29675 4a51edc0e8b02f93563c5baad080c2b9 448 Pfam PF03663 Glycosyl hydrolase family 76 80 378 5.4E-26 T 12-10-2018 IPR005198 Glycoside hydrolase, family 76 UA74_18675 35b30301bdae45655fbbdf3a219af4b8 274 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 261 4.5E-68 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_18675 35b30301bdae45655fbbdf3a219af4b8 274 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 UA74_18675 35b30301bdae45655fbbdf3a219af4b8 274 SUPERFAMILY SSF64005 32 257 2.62E-73 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 UA74_18675 35b30301bdae45655fbbdf3a219af4b8 274 Gene3D G3DSA:3.40.1180.10 2 256 3.7E-86 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 UA74_18675 35b30301bdae45655fbbdf3a219af4b8 274 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 261 3.7E-72 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_18675 35b30301bdae45655fbbdf3a219af4b8 274 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 262 36.857 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_12500 5e8d175aba4106d2615a8f0cf8767fd4 265 Pfam PF01061 ABC-2 type transporter 26 231 3.5E-18 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_12500 5e8d175aba4106d2615a8f0cf8767fd4 265 PIRSF PIRSF006648 8 264 1.1E-19 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SMART SM01018 638 720 5.0E-39 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:1.10.288.10 925 985 1.3E-45 T 12-10-2018 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF56507 900 1187 1.83E-84 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 PIRSF PIRSF000381 3 1187 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF02607 B12 binding domain 642 713 3.8E-23 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF02574 Homocysteine S-methyltransferase 18 308 3.9E-61 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:3.40.50.280 722 877 4.1E-42 T 12-10-2018 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 TIGRFAM TIGR02082 metH: methionine synthase 14 1186 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:3.10.196.10 909 1186 1.3E-45 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF82282 7 382 4.32E-105 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF51717 340 611 1.83E-74 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF52242 720 856 1.37E-38 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:3.20.20.20 329 625 6.0E-96 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF02310 B12 binding domain 726 844 2.8E-19 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:3.20.20.330 4 319 2.0E-92 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 SUPERFAMILY SSF47644 636 719 7.45E-23 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 971 1186 1.2E-31 T 12-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Gene3D G3DSA:1.10.1240.10 630 717 2.7E-28 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_14120 3e4f932fb250ce5a7bcfbb9bac96ff6e 1187 Pfam PF00809 Pterin binding enzyme 344 579 7.7E-45 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 Gene3D G3DSA:3.40.1110.10 470 591 8.0E-88 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 606 616 6.7E-25 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 584 595 6.7E-25 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 309 323 6.7E-25 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 473 6.7E-25 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 682 694 6.7E-25 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 659 678 6.7E-25 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 224 762 4.6E-150 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 SUPERFAMILY SSF81653 265 359 4.18E-25 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 Gene3D G3DSA:3.40.50.1000 440 711 8.0E-88 T 12-10-2018 IPR023214 HAD superfamily UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 SUPERFAMILY SSF81665 213 728 4.97E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 233 739 7.7E-87 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 ProSitePatterns PS01229 Hypothetical cof family signature 2. 659 681 - T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 SUPERFAMILY SSF55008 23 90 1.06E-17 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 Pfam PF00702 haloacid dehalogenase-like hydrolase 455 673 1.8E-45 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 Gene3D G3DSA:3.30.70.100 10 89 9.8E-19 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 178 761 4.0E-175 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 461 467 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 ProSitePatterns PS01047 Heavy-metal-associated domain. 29 57 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 Pfam PF00122 E1-E2 ATPase 262 437 4.6E-52 T 12-10-2018 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 Pfam PF00403 Heavy-metal-associated domain 28 85 1.3E-12 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 631 647 2.8E-6 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 659 675 2.8E-6 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 690 715 2.8E-6 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 SUPERFAMILY SSF56784 457 759 2.22E-55 T 12-10-2018 IPR036412 HAD-like superfamily UA74_07280 721e269ecde04281e99befc8ce9f47ca 787 Gene3D G3DSA:2.70.150.20 252 364 4.0E-35 T 12-10-2018 UA74_07275 6573af496ad0c9423ca12c00abdd1625 224 Pfam PF00293 NUDIX domain 72 187 3.7E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_07275 6573af496ad0c9423ca12c00abdd1625 224 SUPERFAMILY SSF55811 71 201 6.23E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_07275 6573af496ad0c9423ca12c00abdd1625 224 ProSitePatterns PS00893 Nudix box signature. 104 125 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_07275 6573af496ad0c9423ca12c00abdd1625 224 PRINTS PR00502 NUDIX hydrolase family signature 99 113 8.3E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_07275 6573af496ad0c9423ca12c00abdd1625 224 PRINTS PR00502 NUDIX hydrolase family signature 113 128 8.3E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_07275 6573af496ad0c9423ca12c00abdd1625 224 Gene3D G3DSA:3.90.79.10 47 197 2.7E-29 T 12-10-2018 UA74_13295 7f2fc76a9555c6165c8f06266c4c8731 445 Gene3D G3DSA:2.160.20.10 75 444 6.5E-96 T 12-10-2018 IPR012334 Pectin lyase fold UA74_13295 7f2fc76a9555c6165c8f06266c4c8731 445 Pfam PF13229 Right handed beta helix region 188 351 4.3E-10 T 12-10-2018 IPR039448 Right handed beta helix domain UA74_13295 7f2fc76a9555c6165c8f06266c4c8731 445 SUPERFAMILY SSF51126 79 439 1.29E-60 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor UA74_13295 7f2fc76a9555c6165c8f06266c4c8731 445 Pfam PF07602 Protein of unknown function (DUF1565) 87 126 3.6E-5 T 12-10-2018 IPR011459 Domain of unknown function DUF1565 UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:2.40.30.110 764 841 4.9E-26 T 12-10-2018 UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Pfam PF01266 FAD dependent oxidoreductase 6 409 3.9E-46 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.50.50.60 7 423 7.6E-108 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Pfam PF16350 FAD dependent oxidoreductase central domain 412 467 7.3E-19 T 12-10-2018 IPR032503 FAD dependent oxidoreductase, central domain UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF51905 5 455 8.42E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 750 841 1.0E-17 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF101790 767 853 5.89E-22 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.30.70.1400 538 755 9.3E-107 T 12-10-2018 UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.30.9.10 92 372 7.6E-108 T 12-10-2018 UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF103025 462 762 9.26E-93 T 12-10-2018 UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Pfam PF01571 Aminomethyltransferase folate-binding domain 469 742 1.6E-73 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 Gene3D G3DSA:3.30.1360.120 462 732 9.3E-107 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_06595 39c40a6d28e49fbbc22b6cdec64d0dc5 854 SUPERFAMILY SSF54373 226 372 6.28E-21 T 12-10-2018 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 SUPERFAMILY SSF51430 9 265 1.31E-79 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 PIRSF PIRSF000097 111 274 5.4E-37 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 PIRSF PIRSF000097 2 116 1.2E-29 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 158 187 4.0E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 92 110 4.0E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 196 220 4.0E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 124 141 4.0E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 PRINTS PR00069 Aldo-keto reductase signature 36 60 4.0E-38 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 40 57 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 Pfam PF00248 Aldo/keto reductase family 17 259 2.8E-39 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 124 141 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_19615 f7d0913739d22a5a5a5d87db1b8e41bf 278 Gene3D G3DSA:3.20.20.100 1 272 4.6E-92 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_05280 3efabfc399446d754ec38fe2eda78c13 138 Gene3D G3DSA:1.10.10.10 2 127 2.1E-46 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_05280 3efabfc399446d754ec38fe2eda78c13 138 Pfam PF01638 HxlR-like helix-turn-helix 28 113 3.8E-31 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_05280 3efabfc399446d754ec38fe2eda78c13 138 SUPERFAMILY SSF46785 14 126 1.9E-37 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_12835 d12dcbaeb3347d6169439ea8426d3880 277 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 5 55 3.6E-28 T 12-10-2018 UA74_12835 d12dcbaeb3347d6169439ea8426d3880 277 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 237 6.8E-19 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 UA74_12835 d12dcbaeb3347d6169439ea8426d3880 277 Gene3D G3DSA:3.40.50.150 71 266 2.0E-58 T 12-10-2018 UA74_12835 d12dcbaeb3347d6169439ea8426d3880 277 PIRSF PIRSF017269 2 272 2.9E-83 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 UA74_12835 d12dcbaeb3347d6169439ea8426d3880 277 SUPERFAMILY SSF53335 7 260 3.01E-72 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_12835 d12dcbaeb3347d6169439ea8426d3880 277 Gene3D G3DSA:3.10.330.20 2 69 4.2E-24 T 12-10-2018 UA74_04740 fd1d6f11d01cfd80590fe501d5613812 389 SMART SM00450 287 384 1.1E-28 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_04740 fd1d6f11d01cfd80590fe501d5613812 389 Gene3D G3DSA:3.40.50.720 16 262 1.1E-85 T 12-10-2018 UA74_04740 fd1d6f11d01cfd80590fe501d5613812 389 Pfam PF00899 ThiF family 24 255 2.0E-61 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 UA74_04740 fd1d6f11d01cfd80590fe501d5613812 389 SUPERFAMILY SSF69572 10 356 1.57E-97 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 UA74_04740 fd1d6f11d01cfd80590fe501d5613812 389 Pfam PF00581 Rhodanese-like domain 287 380 5.1E-14 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_04740 fd1d6f11d01cfd80590fe501d5613812 389 Gene3D G3DSA:3.40.250.10 284 389 1.4E-24 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_20040 04131f1c14f7f9a38e00e109e114d077 436 SUPERFAMILY SSF53850 39 432 3.11E-58 T 12-10-2018 UA74_20040 04131f1c14f7f9a38e00e109e114d077 436 Gene3D G3DSA:3.40.190.10 46 391 5.5E-60 T 12-10-2018 UA74_20040 04131f1c14f7f9a38e00e109e114d077 436 Pfam PF13416 Bacterial extracellular solute-binding protein 57 366 1.7E-25 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_20040 04131f1c14f7f9a38e00e109e114d077 436 Gene3D G3DSA:3.40.190.10 145 419 5.5E-60 T 12-10-2018 UA74_16795 62c878cb490a8a0d5c584bfa66c58b37 195 SUPERFAMILY SSF47413 11 76 9.29E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_16795 62c878cb490a8a0d5c584bfa66c58b37 195 SUPERFAMILY SSF51182 21 178 3.93E-16 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_16795 62c878cb490a8a0d5c584bfa66c58b37 195 Pfam PF01381 Helix-turn-helix 16 70 1.3E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_16795 62c878cb490a8a0d5c584bfa66c58b37 195 Pfam PF07883 Cupin domain 108 174 2.6E-9 T 12-10-2018 IPR013096 Cupin 2, conserved barrel UA74_16795 62c878cb490a8a0d5c584bfa66c58b37 195 Gene3D G3DSA:1.10.260.40 1 74 6.8E-19 T 12-10-2018 UA74_16795 62c878cb490a8a0d5c584bfa66c58b37 195 SMART SM00530 15 70 2.4E-17 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_16795 62c878cb490a8a0d5c584bfa66c58b37 195 Gene3D G3DSA:2.60.120.10 75 187 2.1E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_08555 4a22ecb0848bc0b0ee78dac3dd10528d 626 Gene3D G3DSA:3.50.30.80 429 579 2.5E-53 T 12-10-2018 UA74_08555 4a22ecb0848bc0b0ee78dac3dd10528d 626 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 515 526 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_08555 4a22ecb0848bc0b0ee78dac3dd10528d 626 Hamap MF_02094 Phosphogluconate dehydratase [edd]. 11 613 56.974 T 12-10-2018 UA74_08555 4a22ecb0848bc0b0ee78dac3dd10528d 626 SUPERFAMILY SSF143975 11 428 1.7E-143 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_08555 4a22ecb0848bc0b0ee78dac3dd10528d 626 Pfam PF00920 Dehydratase family 75 609 4.0E-163 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_08555 4a22ecb0848bc0b0ee78dac3dd10528d 626 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 12 612 5.8E-283 T 12-10-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 UA74_08555 4a22ecb0848bc0b0ee78dac3dd10528d 626 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 164 174 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_08555 4a22ecb0848bc0b0ee78dac3dd10528d 626 SUPERFAMILY SSF52016 429 612 9.42E-57 T 12-10-2018 UA74_01070 c60aec15c1008695637bb74311579c5a 600 Gene3D G3DSA:3.30.160.270 489 600 1.1E-36 T 12-10-2018 UA74_01070 c60aec15c1008695637bb74311579c5a 600 SUPERFAMILY SSF51569 62 370 4.21E-97 T 12-10-2018 UA74_01070 c60aec15c1008695637bb74311579c5a 600 Pfam PF00682 HMGL-like 73 353 1.1E-77 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 UA74_01070 c60aec15c1008695637bb74311579c5a 600 SUPERFAMILY SSF89000 438 488 2.43E-14 T 12-10-2018 UA74_01070 c60aec15c1008695637bb74311579c5a 600 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 80 96 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_01070 c60aec15c1008695637bb74311579c5a 600 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 44 600 54.852 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_01070 c60aec15c1008695637bb74311579c5a 600 Gene3D G3DSA:1.10.1220.20 435 488 1.1E-23 T 12-10-2018 UA74_01070 c60aec15c1008695637bb74311579c5a 600 SUPERFAMILY SSF110921 501 598 2.75E-35 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_01070 c60aec15c1008695637bb74311579c5a 600 Gene3D G3DSA:3.20.20.70 50 426 2.7E-157 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_01070 c60aec15c1008695637bb74311579c5a 600 SMART SM00917 472 599 1.3E-36 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_01070 c60aec15c1008695637bb74311579c5a 600 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 43 600 4.7E-263 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_01070 c60aec15c1008695637bb74311579c5a 600 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 283 296 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_01070 c60aec15c1008695637bb74311579c5a 600 Pfam PF08502 LeuA allosteric (dimerisation) domain 472 598 3.3E-32 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_07625 d14d68d53821dc94a906a3a09cb999bb 482 SMART SM00331 11 236 1.2E-36 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_07625 d14d68d53821dc94a906a3a09cb999bb 482 SUPERFAMILY SSF81606 5 236 3.53E-59 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_07625 d14d68d53821dc94a906a3a09cb999bb 482 SMART SM00332 2 234 5.7E-23 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_07625 d14d68d53821dc94a906a3a09cb999bb 482 Gene3D G3DSA:3.60.40.10 2 237 5.2E-61 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_07625 d14d68d53821dc94a906a3a09cb999bb 482 Pfam PF13672 Protein phosphatase 2C 19 196 1.3E-10 T 12-10-2018 UA74_22905 7f9a8541329270ce090a7310a12a08c6 329 Gene3D G3DSA:3.40.50.720 149 277 3.7E-97 T 12-10-2018 UA74_22905 7f9a8541329270ce090a7310a12a08c6 329 SMART SM00829 7 327 3.8E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_22905 7f9a8541329270ce090a7310a12a08c6 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 2.1E-33 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_22905 7f9a8541329270ce090a7310a12a08c6 329 SUPERFAMILY SSF51735 136 281 1.26E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22905 7f9a8541329270ce090a7310a12a08c6 329 Gene3D G3DSA:3.90.180.10 9 316 3.7E-97 T 12-10-2018 UA74_22905 7f9a8541329270ce090a7310a12a08c6 329 SUPERFAMILY SSF50129 1 171 8.22E-56 T 12-10-2018 IPR011032 GroES-like superfamily UA74_22905 7f9a8541329270ce090a7310a12a08c6 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_22905 7f9a8541329270ce090a7310a12a08c6 329 Pfam PF00107 Zinc-binding dehydrogenase 173 291 6.2E-16 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_11920 3971d53bf2d5859a17047677bde412ad 445 Gene3D G3DSA:4.10.320.10 136 190 2.6E-16 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UA74_11920 3971d53bf2d5859a17047677bde412ad 445 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 3 444 2.7E-138 T 12-10-2018 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 UA74_11920 3971d53bf2d5859a17047677bde412ad 445 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_11920 3971d53bf2d5859a17047677bde412ad 445 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 214 444 2.2E-81 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 UA74_11920 3971d53bf2d5859a17047677bde412ad 445 Gene3D G3DSA:3.30.559.10 198 442 8.2E-94 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_11920 3971d53bf2d5859a17047677bde412ad 445 SUPERFAMILY SSF51230 2 94 8.77E-27 T 12-10-2018 IPR011053 Single hybrid motif UA74_11920 3971d53bf2d5859a17047677bde412ad 445 Gene3D G3DSA:2.40.50.100 1 100 2.1E-29 T 12-10-2018 UA74_11920 3971d53bf2d5859a17047677bde412ad 445 Pfam PF02817 e3 binding domain 143 176 1.6E-14 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 UA74_11920 3971d53bf2d5859a17047677bde412ad 445 Pfam PF00364 Biotin-requiring enzyme 3 73 2.7E-20 T 12-10-2018 IPR000089 Biotin/lipoyl attachment UA74_11920 3971d53bf2d5859a17047677bde412ad 445 SUPERFAMILY SSF52777 214 443 2.45E-80 T 12-10-2018 UA74_11920 3971d53bf2d5859a17047677bde412ad 445 SUPERFAMILY SSF47005 136 180 7.32E-12 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UA74_05825 63358f9c2bd71770793f07fc5b59b25a 382 Gene3D G3DSA:2.60.120.630 1 132 4.6E-18 T 12-10-2018 IPR023131 Mth639-like domain superfamily UA74_05825 63358f9c2bd71770793f07fc5b59b25a 382 Pfam PF04027 Domain of unknown function (DUF371) 9 127 6.3E-15 T 12-10-2018 IPR007171 Protein of unknown function DUF371 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 408 534 2.6E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2033 2151 2.7E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF47336 1562 1671 2.75E-24 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2965 3139 7.9E-59 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1306 1479 4.3E-48 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 552 819 3.0E-82 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2198 2490 8.8E-109 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.47.10 24 484 1.1E-181 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.47.10 1651 2111 3.7E-188 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF08659 KR domain 1308 1478 9.0E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF08659 KR domain 2965 3138 8.8E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.10.129.110 2544 2823 1.8E-111 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.10.129.110 873 1160 1.6E-109 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00823 Phosphopantetheine attachment site 1566 1638 1.2E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00823 Phosphopantetheine attachment site 3226 3298 2.6E-26 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:1.10.1200.10 1554 1639 7.0E-30 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:1.10.1200.10 3209 3301 6.8E-31 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.366.10 550 822 5.0E-117 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.366.10 2196 2493 2.3E-149 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF52151 2195 2476 3.4E-65 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00550 Phosphopantetheine attachment site 1569 1634 1.2E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00550 Phosphopantetheine attachment site 3229 3294 6.2E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00975 Thioesterase domain 3364 3570 3.0E-24 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF08990 Erythronolide synthase docking 3 26 6.2E-7 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1593 1608 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF55048 671 729 7.72E-6 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF51735 2824 2954 2.76E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00826 2555 2713 3.4E-78 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00826 884 1046 7.1E-74 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00824 Thioesterase 3365 3574 2.3E-106 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF53901 31 402 5.92E-102 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF53901 1654 2027 5.51E-108 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00825 Beta-ketoacyl synthase 1659 2083 9.6E-224 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM00825 Beta-ketoacyl synthase 36 458 9.2E-212 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF55048 2318 2380 2.75E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF51735 2963 3188 8.7E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF14765 Polyketide synthase dehydratase 884 1152 9.4E-60 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF14765 Polyketide synthase dehydratase 2555 2823 1.5E-58 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF51735 1305 1494 1.0E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3253 3268 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 290 405 1.4E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1915 2030 2.2E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.30.70.3290 488 865 5.0E-117 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1657 1907 6.4E-90 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 282 2.6E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.50.1820 3308 3578 1.2E-68 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00698 Acyl transferase domain 552 790 5.3E-40 T 12-10-2018 IPR014043 Acyl transferase UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Pfam PF00698 Acyl transferase domain 2197 2509 2.8E-84 T 12-10-2018 IPR014043 Acyl transferase UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF52151 549 812 6.02E-61 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF51735 1163 1293 1.71E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.50.720 1161 1546 2.8E-110 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.40.50.720 2824 3199 1.4E-115 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1820 1836 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 195 211 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM01294 1567 1634 6.5E-6 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SMART SM01294 3228 3294 2.7E-4 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 Gene3D G3DSA:3.30.70.3290 2115 2536 2.3E-149 T 12-10-2018 UA74_17305 2f0511c19fb8799e78c3655a1455da52 3580 SUPERFAMILY SSF53474 3256 3575 6.46E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_25320 30282c5f7f028670c34d78a504b58a09 348 SUPERFAMILY SSF50129 9 171 1.19E-52 T 12-10-2018 IPR011032 GroES-like superfamily UA74_25320 30282c5f7f028670c34d78a504b58a09 348 SUPERFAMILY SSF51735 148 311 1.88E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25320 30282c5f7f028670c34d78a504b58a09 348 SMART SM00829 11 341 1.9E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_25320 30282c5f7f028670c34d78a504b58a09 348 Gene3D G3DSA:3.40.50.720 159 313 3.2E-137 T 12-10-2018 UA74_25320 30282c5f7f028670c34d78a504b58a09 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_25320 30282c5f7f028670c34d78a504b58a09 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 142 1.7E-28 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_25320 30282c5f7f028670c34d78a504b58a09 348 Gene3D G3DSA:3.90.180.10 14 341 3.2E-137 T 12-10-2018 UA74_25320 30282c5f7f028670c34d78a504b58a09 348 Pfam PF00107 Zinc-binding dehydrogenase 185 307 1.6E-20 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_02600 dae7191229beaf56e2fc0e8c998b1928 188 Pfam PF12838 4Fe-4S dicluster domain 52 110 5.1E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_02600 dae7191229beaf56e2fc0e8c998b1928 188 Gene3D G3DSA:3.30.70.3270 26 182 1.0E-45 T 12-10-2018 UA74_02600 dae7191229beaf56e2fc0e8c998b1928 188 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 9 136 2.6E-39 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02600 dae7191229beaf56e2fc0e8c998b1928 188 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 146 26.782 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02600 dae7191229beaf56e2fc0e8c998b1928 188 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_02600 dae7191229beaf56e2fc0e8c998b1928 188 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_02600 dae7191229beaf56e2fc0e8c998b1928 188 SUPERFAMILY SSF54862 26 141 2.55E-25 T 12-10-2018 UA74_25085 626f9c445fba2e7d7db444221128dd89 355 SUPERFAMILY SSF51679 45 354 1.96E-78 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_25085 626f9c445fba2e7d7db444221128dd89 355 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 47 275 1.1E-91 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c UA74_25085 626f9c445fba2e7d7db444221128dd89 355 Pfam PF00296 Luciferase-like monooxygenase 49 295 5.9E-53 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_25085 626f9c445fba2e7d7db444221128dd89 355 Gene3D G3DSA:3.20.20.30 40 355 4.0E-77 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 1833 2070 4.45E-41 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.300.30 1465 1557 5.9E-22 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.300.30 425 517 2.2E-21 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00012 Phosphopantetheine attachment site. 554 569 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SMART SM00823 Phosphopantetheine attachment site 1573 1642 0.098 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SMART SM00823 Phosphopantetheine attachment site 2630 2701 0.015 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SMART SM00823 Phosphopantetheine attachment site 527 599 0.016 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 3349 3585 2.11E-44 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00501 AMP-binding enzyme 1080 1470 3.9E-75 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00501 AMP-binding enzyme 32 429 5.5E-83 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00501 AMP-binding enzyme 2109 2493 3.4E-90 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 3177 3347 6.56E-38 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.559.30 1831 2083 1.3E-90 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF56801 1070 1586 4.97E-126 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 2900 3139 4.11E-31 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 807 1048 4.39E-49 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF13193 AMP-binding enzyme C-terminal domain 437 505 5.6E-6 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF13193 AMP-binding enzyme C-terminal domain 1478 1546 6.5E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2240 2251 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:1.10.1200.10 518 601 3.1E-19 T 12-10-2018 IPR036736 ACP-like superfamily UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00668 Condensation domain 625 1056 2.2E-68 T 12-10-2018 IPR001242 Condensation domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00668 Condensation domain 2718 3049 3.3E-38 T 12-10-2018 IPR001242 Condensation domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00668 Condensation domain 3172 3583 7.7E-69 T 12-10-2018 IPR001242 Condensation domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00668 Condensation domain 1657 2087 1.6E-59 T 12-10-2018 IPR001242 Condensation domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.559.10 1661 2016 1.3E-90 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2127 2518 2.0E-120 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 46 453 7.7E-111 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1101 1494 1.6E-115 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.559.30 2884 3140 1.8E-41 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.40.50.12780 2095 2488 2.3E-123 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.40.50.12780 17 423 1.0E-111 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.40.50.12780 1069 1464 9.3E-115 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 622 820 1.33E-38 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 2715 2913 1.22E-27 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.559.10 2706 2881 1.6E-34 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF52777 1655 1845 2.89E-36 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.559.10 3177 3534 1.1E-103 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.559.10 628 994 2.9E-104 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.559.30 3349 3583 1.1E-103 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.559.30 806 1057 2.9E-104 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1597 1612 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2657 2672 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:1.10.1200.10 2626 2698 7.2E-20 T 12-10-2018 IPR036736 ACP-like superfamily UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:1.10.1200.10 1565 1638 1.4E-21 T 12-10-2018 IPR036736 ACP-like superfamily UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF47336 525 595 1.57E-13 T 12-10-2018 IPR036736 ACP-like superfamily UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00550 Phosphopantetheine attachment site 532 595 1.2E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00550 Phosphopantetheine attachment site 2632 2694 3.9E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Pfam PF00550 Phosphopantetheine attachment site 1578 1635 5.0E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF56801 2065 2643 1.7E-138 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 Gene3D G3DSA:3.30.300.30 2490 2625 6.1E-25 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF47336 2623 2694 3.66E-14 T 12-10-2018 IPR036736 ACP-like superfamily UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF56801 21 543 3.92E-126 T 12-10-2018 UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 SUPERFAMILY SSF47336 1565 1636 4.58E-15 T 12-10-2018 IPR036736 ACP-like superfamily UA74_14815 870bd2a27802fc09dad50409dd4b1204 3592 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1213 1224 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_23380 f935fb12ba501794d8b2bfccb06e13ce 295 Pfam PF04954 Siderophore-interacting protein 147 264 1.7E-36 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain UA74_23380 f935fb12ba501794d8b2bfccb06e13ce 295 Gene3D G3DSA:3.40.50.80 142 286 4.4E-43 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_23380 f935fb12ba501794d8b2bfccb06e13ce 295 SUPERFAMILY SSF63380 8 136 1.04E-12 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_23380 f935fb12ba501794d8b2bfccb06e13ce 295 Pfam PF08021 Siderophore-interacting FAD-binding domain 11 132 2.2E-34 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting UA74_23380 f935fb12ba501794d8b2bfccb06e13ce 295 Gene3D G3DSA:2.40.30.10 1 133 1.6E-38 T 12-10-2018 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Pfam PF08659 KR domain 2224 2444 1.7E-29 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SUPERFAMILY SSF51735 2026 2188 3.81E-6 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SUPERFAMILY SSF51412 358 617 1.19E-14 T 12-10-2018 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Gene3D G3DSA:1.10.1200.10 1798 1894 1.0E-21 T 12-10-2018 IPR036736 ACP-like superfamily UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SUPERFAMILY SSF52151 1279 1575 6.54E-50 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Gene3D G3DSA:3.30.70.250 1406 1476 2.1E-72 T 12-10-2018 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SUPERFAMILY SSF53901 721 1113 6.73E-73 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Gene3D G3DSA:3.40.47.10 721 1232 7.4E-156 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Gene3D G3DSA:3.40.50.720 2023 2495 1.7E-68 T 12-10-2018 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SUPERFAMILY SSF51412 43 202 1.65E-13 T 12-10-2018 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SMART SM00825 Beta-ketoacyl synthase 726 1167 9.9E-101 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SUPERFAMILY SSF51735 2221 2481 5.67E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Gene3D G3DSA:3.40.366.10 1282 1563 2.1E-72 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2223 2447 7.1E-12 T 12-10-2018 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SUPERFAMILY SSF55048 1408 1473 6.8E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1282 1594 6.9E-33 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 997 1114 8.2E-38 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 902 918 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 SUPERFAMILY SSF47336 1810 1898 1.25E-9 T 12-10-2018 IPR036736 ACP-like superfamily UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 725 989 3.0E-66 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Pfam PF03060 Nitronate monooxygenase 359 690 2.5E-13 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Pfam PF00698 Acyl transferase domain 1282 1562 3.1E-30 T 12-10-2018 IPR014043 Acyl transferase UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Gene3D G3DSA:3.20.20.70 357 715 6.7E-67 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_21850 461749bab54f8cca7dc203d826e283a8 2503 Gene3D G3DSA:3.20.20.70 34 292 1.5E-30 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 SUPERFAMILY SSF46894 152 223 5.44E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 Gene3D G3DSA:3.40.50.12740 5 223 1.3E-67 T 12-10-2018 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 SMART SM00421 160 217 9.6E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 Pfam PF00072 Response regulator receiver domain 7 119 5.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 SMART SM00448 5 120 1.0E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 217 7.7E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 5.6E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 5.6E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 5.6E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05260 e1598b6ede9f4e042bcde4139705431d 227 SUPERFAMILY SSF52172 4 137 8.11E-31 T 12-10-2018 IPR011006 CheY-like superfamily UA74_24080 660fbf615cc5387a813763f73c1cef85 484 SMART SM00773 10 83 5.1E-17 T 12-10-2018 IPR008893 WGR domain UA74_24080 660fbf615cc5387a813763f73c1cef85 484 Gene3D G3DSA:2.20.140.10 14 85 1.3E-17 T 12-10-2018 IPR036930 WGR domain superfamily UA74_24080 660fbf615cc5387a813763f73c1cef85 484 SUPERFAMILY SSF50998 102 375 5.1E-17 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily UA74_24080 660fbf615cc5387a813763f73c1cef85 484 Gene3D G3DSA:2.130.10.10 238 433 1.3E-14 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_24080 660fbf615cc5387a813763f73c1cef85 484 Pfam PF13360 PQQ-like domain 249 375 1.8E-9 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat UA74_24080 660fbf615cc5387a813763f73c1cef85 484 SUPERFAMILY SSF142921 13 78 2.09E-9 T 12-10-2018 IPR036930 WGR domain superfamily UA74_24080 660fbf615cc5387a813763f73c1cef85 484 Pfam PF05406 WGR domain 12 79 4.4E-15 T 12-10-2018 IPR008893 WGR domain UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 SUPERFAMILY SSF51905 24 391 3.76E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 Gene3D G3DSA:3.40.30.120 423 547 3.3E-28 T 12-10-2018 UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 Pfam PF01494 FAD binding domain 24 379 1.5E-66 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 Gene3D G3DSA:3.30.70.2450 220 291 9.4E-12 T 12-10-2018 UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 Gene3D G3DSA:3.50.50.60 15 211 4.5E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 Gene3D G3DSA:3.50.50.60 292 404 1.9E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 329 345 1.1E-42 T 12-10-2018 UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 365 381 1.1E-42 T 12-10-2018 UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 24 46 1.1E-42 T 12-10-2018 UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 1.1E-42 T 12-10-2018 UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 329 1.1E-42 T 12-10-2018 UA74_05845 0b5499a0cca4295482b4bdd59dd3785c 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 347 365 1.1E-42 T 12-10-2018 UA74_28160 f411b856566bfee95f3d7d81a2687245 263 Pfam PF13560 Helix-turn-helix domain 1 52 3.2E-6 T 12-10-2018 UA74_00860 9859f6c911a87daeb44404fb230da792 159 Pfam PF14437 MafB19-like deaminase 10 156 2.4E-28 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 UA74_00860 9859f6c911a87daeb44404fb230da792 159 Gene3D G3DSA:3.40.140.10 2 159 5.2E-54 T 12-10-2018 UA74_00860 9859f6c911a87daeb44404fb230da792 159 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 14 157 46.359 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 UA74_00860 9859f6c911a87daeb44404fb230da792 159 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 60 98 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UA74_00860 9859f6c911a87daeb44404fb230da792 159 SUPERFAMILY SSF53927 7 157 4.52E-49 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UA74_26445 b78032879c040b9a5c2268863d73e1b6 158 Gene3D G3DSA:3.90.960.10 2 158 7.8E-56 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UA74_26445 b78032879c040b9a5c2268863d73e1b6 158 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 156 6.8E-54 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC UA74_26445 b78032879c040b9a5c2268863d73e1b6 158 Pfam PF04073 Aminoacyl-tRNA editing domain 35 147 3.1E-25 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_26445 b78032879c040b9a5c2268863d73e1b6 158 PIRSF PIRSF006181 2 158 2.1E-50 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC UA74_26445 b78032879c040b9a5c2268863d73e1b6 158 SUPERFAMILY SSF55826 6 156 6.15E-41 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UA74_15585 e13e644e9c23443b28454bee825088fb 348 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 321 1.2E-114 T 12-10-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c UA74_15585 e13e644e9c23443b28454bee825088fb 348 SUPERFAMILY SSF51679 10 339 9.86E-68 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_15585 e13e644e9c23443b28454bee825088fb 348 Gene3D G3DSA:3.20.20.30 12 341 1.9E-82 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_15585 e13e644e9c23443b28454bee825088fb 348 Pfam PF00296 Luciferase-like monooxygenase 16 317 1.2E-78 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_13690 aa2a80196679734a1dc17f772521402c 189 SUPERFAMILY SSF88946 11 108 2.71E-16 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_13690 aa2a80196679734a1dc17f772521402c 189 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 15 169 5.5E-45 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_13690 aa2a80196679734a1dc17f772521402c 189 Pfam PF08281 Sigma-70, region 4 114 164 1.2E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_13690 aa2a80196679734a1dc17f772521402c 189 SUPERFAMILY SSF88659 92 172 5.61E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_13690 aa2a80196679734a1dc17f772521402c 189 Gene3D G3DSA:1.10.10.10 108 175 5.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13690 aa2a80196679734a1dc17f772521402c 189 Pfam PF04542 Sigma-70 region 2 24 90 1.8E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_13690 aa2a80196679734a1dc17f772521402c 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 168 2.1E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_13690 aa2a80196679734a1dc17f772521402c 189 Gene3D G3DSA:1.10.1740.10 8 107 6.5E-11 T 12-10-2018 UA74_13315 afcb23038e0932b7980f070b89095486 500 Gene3D G3DSA:3.40.50.300 262 497 6.1E-41 T 12-10-2018 UA74_13315 afcb23038e0932b7980f070b89095486 500 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_13315 afcb23038e0932b7980f070b89095486 500 SUPERFAMILY SSF52540 10 232 8.37E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13315 afcb23038e0932b7980f070b89095486 500 Pfam PF00005 ABC transporter 277 429 7.0E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13315 afcb23038e0932b7980f070b89095486 500 SMART SM00382 284 494 0.1 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13315 afcb23038e0932b7980f070b89095486 500 SMART SM00382 33 221 1.6E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13315 afcb23038e0932b7980f070b89095486 500 Gene3D G3DSA:3.40.50.300 3 249 6.1E-59 T 12-10-2018 UA74_13315 afcb23038e0932b7980f070b89095486 500 Pfam PF00005 ABC transporter 26 173 9.9E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13315 afcb23038e0932b7980f070b89095486 500 SUPERFAMILY SSF52540 273 484 1.87E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21375 575a024ca231b6acbd312c0027b1e466 724 PRINTS PR00364 Disease resistance protein signature 244 258 5.2E-11 T 12-10-2018 UA74_21375 575a024ca231b6acbd312c0027b1e466 724 PRINTS PR00364 Disease resistance protein signature 80 95 5.2E-11 T 12-10-2018 UA74_21375 575a024ca231b6acbd312c0027b1e466 724 PRINTS PR00364 Disease resistance protein signature 157 171 5.2E-11 T 12-10-2018 UA74_21375 575a024ca231b6acbd312c0027b1e466 724 Gene3D G3DSA:3.40.50.300 41 199 1.2E-23 T 12-10-2018 UA74_21375 575a024ca231b6acbd312c0027b1e466 724 SUPERFAMILY SSF48452 484 688 1.7E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_21375 575a024ca231b6acbd312c0027b1e466 724 Gene3D G3DSA:1.25.40.10 429 525 1.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_21375 575a024ca231b6acbd312c0027b1e466 724 Gene3D G3DSA:1.25.40.10 526 721 1.1E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_21375 575a024ca231b6acbd312c0027b1e466 724 Pfam PF00931 NB-ARC domain 76 302 1.6E-9 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_21375 575a024ca231b6acbd312c0027b1e466 724 SUPERFAMILY SSF52540 37 310 1.96E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 279 9.5E-104 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 Pfam PF02780 Transketolase, C-terminal domain 505 617 4.1E-27 T 12-10-2018 IPR033248 Transketolase, C-terminal domain UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 SUPERFAMILY SSF52922 506 625 9.03E-25 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 Gene3D G3DSA:3.40.50.920 502 626 4.3E-28 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 SUPERFAMILY SSF52518 293 477 7.64E-54 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 7 621 2.1E-179 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 626 40.519 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 Pfam PF02779 Transketolase, pyrimidine binding domain 315 477 4.2E-39 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 Gene3D G3DSA:3.40.50.970 312 485 2.2E-58 T 12-10-2018 UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 SUPERFAMILY SSF52518 3 345 3.8E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_16385 2dad8d443ae79d8f9b5c6a987c016443 646 SMART SM00861 315 479 1.6E-53 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_05695 4386df7227dbfb2685a4c218aa7df7f4 314 Gene3D G3DSA:1.10.3210.10 87 222 3.9E-31 T 12-10-2018 UA74_05695 4386df7227dbfb2685a4c218aa7df7f4 314 Pfam PF13023 HD domain 102 209 1.2E-19 T 12-10-2018 IPR006674 HD domain UA74_05695 4386df7227dbfb2685a4c218aa7df7f4 314 SUPERFAMILY SSF109604 96 210 3.77E-23 T 12-10-2018 UA74_05695 4386df7227dbfb2685a4c218aa7df7f4 314 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 2.9E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_05695 4386df7227dbfb2685a4c218aa7df7f4 314 Gene3D G3DSA:1.10.10.10 2 77 6.9E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_05695 4386df7227dbfb2685a4c218aa7df7f4 314 SUPERFAMILY SSF46785 5 84 8.95E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_05695 4386df7227dbfb2685a4c218aa7df7f4 314 SMART SM00471 119 313 0.0091 T 12-10-2018 IPR003607 HD/PDEase domain UA74_05695 4386df7227dbfb2685a4c218aa7df7f4 314 SMART SM00345 16 75 5.8E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_00910 091851db59daedbb65845023dce2e884 282 SMART SM00420 8 59 1.5E-12 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_00910 091851db59daedbb65845023dce2e884 282 SUPERFAMILY SSF100950 75 235 3.77E-25 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_00910 091851db59daedbb65845023dce2e884 282 Pfam PF08220 DeoR-like helix-turn-helix domain 8 58 2.3E-13 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_00910 091851db59daedbb65845023dce2e884 282 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 6.9E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_00910 091851db59daedbb65845023dce2e884 282 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 6.9E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_00910 091851db59daedbb65845023dce2e884 282 SMART SM01134 73 234 2.5E-54 T 12-10-2018 UA74_00910 091851db59daedbb65845023dce2e884 282 SUPERFAMILY SSF46785 12 60 1.71E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_00910 091851db59daedbb65845023dce2e884 282 Pfam PF00455 DeoR C terminal sensor domain 75 232 6.8E-40 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 PRINTS PR00126 ATP synthase gamma subunit signature 252 271 1.1E-34 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.1E-34 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 PRINTS PR00126 ATP synthase gamma subunit signature 181 198 1.1E-34 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 PRINTS PR00126 ATP synthase gamma subunit signature 283 304 1.1E-34 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 Gene3D G3DSA:1.10.287.80 7 301 5.7E-93 T 12-10-2018 UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 Gene3D G3DSA:3.40.1380.10 61 224 5.7E-93 T 12-10-2018 UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 SUPERFAMILY SSF52943 3 305 2.62E-80 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 305 4.6E-102 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 Pfam PF00231 ATP synthase 5 305 1.7E-90 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07060 4da38a2adae39a99aff8bee2afe6852e 312 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 305 35.235 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_05120 a18526d4cc74bf027baefab51deeb2a2 297 SUPERFAMILY SSF75217 140 293 1.31E-35 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_05120 a18526d4cc74bf027baefab51deeb2a2 297 Gene3D G3DSA:3.40.1280.10 139 296 6.0E-40 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_05120 a18526d4cc74bf027baefab51deeb2a2 297 Gene3D G3DSA:3.30.1330.30 35 134 1.3E-9 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_05120 a18526d4cc74bf027baefab51deeb2a2 297 Pfam PF00588 SpoU rRNA Methylase family 147 288 2.0E-27 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_05120 a18526d4cc74bf027baefab51deeb2a2 297 SUPERFAMILY SSF55315 36 135 4.0E-7 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_03070 2bb3cfc848fecbc62563fc83af2be03c 276 Gene3D G3DSA:1.10.260.40 1 67 6.0E-9 T 12-10-2018 UA74_03070 2bb3cfc848fecbc62563fc83af2be03c 276 Pfam PF13560 Helix-turn-helix domain 3 64 1.2E-15 T 12-10-2018 UA74_03070 2bb3cfc848fecbc62563fc83af2be03c 276 SMART SM00530 6 61 4.5E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_03070 2bb3cfc848fecbc62563fc83af2be03c 276 SUPERFAMILY SSF47413 3 60 1.18E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 SUPERFAMILY SSF49384 431 536 1.74E-33 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 Gene3D G3DSA:2.60.40.290 429 538 1.4E-35 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 Gene3D G3DSA:2.60.40.10 336 426 1.6E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 SUPERFAMILY SSF51445 31 326 3.13E-76 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 SMART SM00060 338 415 1.7E-11 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 SUPERFAMILY SSF49265 335 429 8.6E-18 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 Pfam PF00041 Fibronectin type III domain 341 415 1.9E-11 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 SMART SM00637 435 535 2.6E-43 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 Pfam PF00553 Cellulose binding domain 435 535 4.6E-30 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 150 159 - T 12-10-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 41 286 2.0E-36 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 UA74_13020 8ba3c0fed987c660429fbd285cfc9e64 538 Gene3D G3DSA:3.20.20.80 22 328 1.1E-88 T 12-10-2018 UA74_05470 2f545f5c8208c4842d386b3c8f3c6273 437 SUPERFAMILY SSF53383 17 432 1.07E-109 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_05470 2f545f5c8208c4842d386b3c8f3c6273 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_05470 2f545f5c8208c4842d386b3c8f3c6273 437 Pfam PF00202 Aminotransferase class-III 26 430 5.1E-84 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_05470 2f545f5c8208c4842d386b3c8f3c6273 437 Gene3D G3DSA:3.40.640.10 60 324 3.4E-132 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_05470 2f545f5c8208c4842d386b3c8f3c6273 437 Gene3D G3DSA:3.90.1150.10 31 425 3.4E-132 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 403 580 1.3E-87 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 PIRSF PIRSF017245 3 794 0.0 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 Gene3D G3DSA:3.40.50.970 2 390 7.0E-171 T 12-10-2018 UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 Hamap MF_01403 Probable phosphoketolase. 9 794 40.336 T 12-10-2018 IPR023962 Probable phosphoketolase UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 Pfam PF09363 XFP C-terminal domain 591 792 1.2E-90 T 12-10-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 ProSitePatterns PS60002 Phosphoketolase signature 1. 148 154 - T 12-10-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 Pfam PF09364 XFP N-terminal domain 12 388 3.3E-179 T 12-10-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 SUPERFAMILY SSF52518 380 594 9.57E-27 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 Gene3D G3DSA:3.40.50.920 611 798 4.2E-78 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 ProSitePatterns PS60003 Phosphoketolase signature 2. 161 179 - T 12-10-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 SUPERFAMILY SSF52518 12 373 3.71E-70 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_08020 bdaf01a406e00211f6756354b4dd360d 799 Gene3D G3DSA:3.40.50.970 391 610 4.7E-102 T 12-10-2018 UA74_07545 e8d15abff630767cdcbbbbf429643977 308 Pfam PF03466 LysR substrate binding domain 90 290 6.2E-27 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_07545 e8d15abff630767cdcbbbbf429643977 308 Gene3D G3DSA:1.10.10.10 1 87 3.2E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_07545 e8d15abff630767cdcbbbbf429643977 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_07545 e8d15abff630767cdcbbbbf429643977 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_07545 e8d15abff630767cdcbbbbf429643977 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_07545 e8d15abff630767cdcbbbbf429643977 308 SUPERFAMILY SSF53850 92 293 7.6E-24 T 12-10-2018 UA74_07545 e8d15abff630767cdcbbbbf429643977 308 SUPERFAMILY SSF46785 4 86 2.66E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_07545 e8d15abff630767cdcbbbbf429643977 308 Gene3D G3DSA:3.40.190.10 95 290 3.1E-28 T 12-10-2018 UA74_07545 e8d15abff630767cdcbbbbf429643977 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 8.4E-25 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_07545 e8d15abff630767cdcbbbbf429643977 308 Gene3D G3DSA:3.40.190.10 165 268 3.1E-28 T 12-10-2018 UA74_03630 dffbc93dfb7bb7f41090b68d2de041dc 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 4.7E-43 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UA74_03630 dffbc93dfb7bb7f41090b68d2de041dc 326 SMART SM01400 12 128 1.0E-67 T 12-10-2018 UA74_03630 dffbc93dfb7bb7f41090b68d2de041dc 326 Gene3D G3DSA:3.40.50.2020 155 299 4.8E-108 T 12-10-2018 UA74_03630 dffbc93dfb7bb7f41090b68d2de041dc 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 UA74_03630 dffbc93dfb7bb7f41090b68d2de041dc 326 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 12 323 44.284 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 UA74_03630 dffbc93dfb7bb7f41090b68d2de041dc 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 322 9.0E-112 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UA74_03630 dffbc93dfb7bb7f41090b68d2de041dc 326 SUPERFAMILY SSF53271 77 314 6.78E-60 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_03630 dffbc93dfb7bb7f41090b68d2de041dc 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 4.9E-20 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UA74_03630 dffbc93dfb7bb7f41090b68d2de041dc 326 Gene3D G3DSA:3.40.50.2020 15 310 4.8E-108 T 12-10-2018 UA74_25500 b473d2e1c45181d3cfa3343b6552fe87 404 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 1 368 3.0E-88 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 UA74_25500 b473d2e1c45181d3cfa3343b6552fe87 404 Gene3D G3DSA:3.30.420.40 140 329 1.1E-90 T 12-10-2018 UA74_25500 b473d2e1c45181d3cfa3343b6552fe87 404 Gene3D G3DSA:3.30.420.40 2 364 1.1E-90 T 12-10-2018 UA74_25500 b473d2e1c45181d3cfa3343b6552fe87 404 SUPERFAMILY SSF53067 138 320 2.41E-8 T 12-10-2018 UA74_21505 949143098c9df84cf2c4debbcbabafb8 404 SUPERFAMILY SSF53474 195 286 2.97E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_21505 949143098c9df84cf2c4debbcbabafb8 404 Pfam PF06259 Alpha/beta hydrolase 137 310 9.6E-44 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 UA74_21505 949143098c9df84cf2c4debbcbabafb8 404 Gene3D G3DSA:3.40.50.1820 156 358 2.9E-5 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 SUPERFAMILY SSF46894 150 227 3.03E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 Pfam PF00072 Response regulator receiver domain 16 128 2.1E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 Gene3D G3DSA:3.40.50.12740 14 227 1.8E-61 T 12-10-2018 UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 SUPERFAMILY SSF52172 13 146 2.56E-29 T 12-10-2018 IPR011006 CheY-like superfamily UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 181 208 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 221 4.7E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 SMART SM00448 14 128 9.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 SMART SM00421 164 221 4.3E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 209 8.7E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 181 8.7E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27805 e0f18cbec9bb9dd753ba0c7f3ab7da9a 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 197 8.7E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18380 3721483b6b70b8e46a44a29f26d66cb3 588 Pfam PF13424 Tetratricopeptide repeat 207 273 2.4E-7 T 12-10-2018 UA74_18380 3721483b6b70b8e46a44a29f26d66cb3 588 SUPERFAMILY SSF48452 216 392 4.64E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_18380 3721483b6b70b8e46a44a29f26d66cb3 588 SUPERFAMILY SSF48452 73 197 9.39E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_18380 3721483b6b70b8e46a44a29f26d66cb3 588 Gene3D G3DSA:1.25.40.10 60 240 3.4E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_18380 3721483b6b70b8e46a44a29f26d66cb3 588 Gene3D G3DSA:1.25.40.10 241 421 7.1E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19690 c78253f18b186ee728cdf29776774b1b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 3.3E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19690 c78253f18b186ee728cdf29776774b1b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 3.3E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19690 c78253f18b186ee728cdf29776774b1b 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 3.3E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19690 c78253f18b186ee728cdf29776774b1b 121 SUPERFAMILY SSF46785 11 108 1.17E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_19690 c78253f18b186ee728cdf29776774b1b 121 Pfam PF12840 Helix-turn-helix domain 13 72 1.1E-14 T 12-10-2018 UA74_19690 c78253f18b186ee728cdf29776774b1b 121 Gene3D G3DSA:1.10.10.10 6 115 8.0E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19690 c78253f18b186ee728cdf29776774b1b 121 SMART SM00418 14 88 5.0E-16 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_00460 02adb68f09e9e921addf34299db9e566 309 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 42 292 1.4E-38 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UA74_00460 02adb68f09e9e921addf34299db9e566 309 Gene3D G3DSA:3.20.20.190 19 304 7.9E-66 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_00460 02adb68f09e9e921addf34299db9e566 309 SUPERFAMILY SSF51695 37 298 2.88E-60 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_23360 88d2185987e000da26d75e28b67396f3 113 SMART SM00418 9 83 3.4E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_23360 88d2185987e000da26d75e28b67396f3 113 SUPERFAMILY SSF46785 6 99 1.89E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_23360 88d2185987e000da26d75e28b67396f3 113 Pfam PF12840 Helix-turn-helix domain 10 65 2.1E-16 T 12-10-2018 UA74_23360 88d2185987e000da26d75e28b67396f3 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 1.1E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_23360 88d2185987e000da26d75e28b67396f3 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.1E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_23360 88d2185987e000da26d75e28b67396f3 113 Gene3D G3DSA:1.10.10.10 1 110 6.5E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 Gene3D G3DSA:3.50.50.60 144 261 5.2E-108 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PIRSF PIRSF000350 2 449 5.1E-74 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 3.6E-38 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 3.6E-38 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 3.6E-38 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.6E-38 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 3.6E-38 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 5.5E-70 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 5.5E-70 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 5.5E-70 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 5.5E-70 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 5.5E-70 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 5.5E-70 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 5.5E-70 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 5.5E-70 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 5.5E-70 T 12-10-2018 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 447 9.0E-25 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 317 2.1E-73 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 457 1.4E-137 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 Gene3D G3DSA:3.50.50.60 7 322 5.2E-108 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 SUPERFAMILY SSF55424 333 457 2.06E-29 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 SUPERFAMILY SSF51905 3 326 9.67E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_25065 44288104e7212a478c6fe35ff1baf56f 460 Gene3D G3DSA:3.30.390.30 336 458 1.0E-32 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_02370 7718a6c43932b2acbb90b53559b64266 446 Gene3D G3DSA:3.90.1150.10 20 424 2.1E-152 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_02370 7718a6c43932b2acbb90b53559b64266 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 247 283 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_02370 7718a6c43932b2acbb90b53559b64266 446 Pfam PF00202 Aminotransferase class-III 46 430 1.5E-82 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_02370 7718a6c43932b2acbb90b53559b64266 446 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 17 430 1.9E-175 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 UA74_02370 7718a6c43932b2acbb90b53559b64266 446 Gene3D G3DSA:3.40.640.10 82 330 2.1E-152 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_02370 7718a6c43932b2acbb90b53559b64266 446 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 16 437 93.65 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 UA74_02370 7718a6c43932b2acbb90b53559b64266 446 SUPERFAMILY SSF53383 14 433 5.27E-114 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_04460 278ea8bf4104cb66bc4d69208c42f9bd 271 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 256 1.1E-80 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 UA74_04460 278ea8bf4104cb66bc4d69208c42f9bd 271 SUPERFAMILY SSF51717 1 259 3.4E-76 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_04460 278ea8bf4104cb66bc4d69208c42f9bd 271 Gene3D G3DSA:3.20.20.20 1 271 2.3E-83 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_04460 278ea8bf4104cb66bc4d69208c42f9bd 271 Pfam PF00809 Pterin binding enzyme 1 242 6.2E-67 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_18115 b39b7caa3755b9bc54087c0a42d5b618 301 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_18115 b39b7caa3755b9bc54087c0a42d5b618 301 SUPERFAMILY SSF52540 5 220 2.21E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18115 b39b7caa3755b9bc54087c0a42d5b618 301 Pfam PF00005 ABC transporter 21 161 6.8E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_18115 b39b7caa3755b9bc54087c0a42d5b618 301 SMART SM00382 29 216 1.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_18115 b39b7caa3755b9bc54087c0a42d5b618 301 Gene3D G3DSA:3.40.50.300 3 232 1.6E-58 T 12-10-2018 UA74_10475 66a537e4b0e4dfce1f8492539312ab8d 134 Pfam PF12840 Helix-turn-helix domain 6 64 6.1E-16 T 12-10-2018 UA74_10475 66a537e4b0e4dfce1f8492539312ab8d 134 SMART SM00418 5 84 2.3E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_10475 66a537e4b0e4dfce1f8492539312ab8d 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 2.7E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_10475 66a537e4b0e4dfce1f8492539312ab8d 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 2.7E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_10475 66a537e4b0e4dfce1f8492539312ab8d 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 2.7E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_10475 66a537e4b0e4dfce1f8492539312ab8d 134 Gene3D G3DSA:1.10.10.10 2 107 3.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10475 66a537e4b0e4dfce1f8492539312ab8d 134 SUPERFAMILY SSF46785 5 97 1.41E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_29325 e4c70fce2d93d789f1fd04a3f051aa2e 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 160 3.2E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_29325 e4c70fce2d93d789f1fd04a3f051aa2e 172 Gene3D G3DSA:1.10.10.10 80 164 9.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_29325 e4c70fce2d93d789f1fd04a3f051aa2e 172 SUPERFAMILY SSF88659 81 163 3.92E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_29325 e4c70fce2d93d789f1fd04a3f051aa2e 172 Pfam PF08281 Sigma-70, region 4 105 157 9.7E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_29325 e4c70fce2d93d789f1fd04a3f051aa2e 172 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 161 2.1E-48 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_29325 e4c70fce2d93d789f1fd04a3f051aa2e 172 Gene3D G3DSA:1.10.1740.10 1 79 6.8E-10 T 12-10-2018 UA74_29325 e4c70fce2d93d789f1fd04a3f051aa2e 172 Pfam PF04542 Sigma-70 region 2 17 79 1.6E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_29325 e4c70fce2d93d789f1fd04a3f051aa2e 172 SUPERFAMILY SSF88946 4 92 4.71E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 Pfam PF01225 Mur ligase family, catalytic domain 42 142 2.8E-25 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 39 504 38.237 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 Gene3D G3DSA:3.40.1190.10 132 354 9.2E-66 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 Pfam PF02875 Mur ligase family, glutamate ligase domain 357 442 3.6E-25 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 SUPERFAMILY SSF51984 40 130 1.29E-22 T 12-10-2018 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 42 498 7.5E-145 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 Gene3D G3DSA:3.40.50.720 40 131 2.0E-29 T 12-10-2018 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 SUPERFAMILY SSF53244 356 500 2.09E-45 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 SUPERFAMILY SSF53623 129 355 2.75E-52 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 Pfam PF08245 Mur ligase middle domain 148 336 5.6E-27 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UA74_09650 9b99986e08e9b54efc8101fb467613c9 508 Gene3D G3DSA:3.90.190.20 355 507 5.3E-54 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_08180 5b1a1a4d15050bc710639ee5e0785217 949 Pfam PF10150 Ribonuclease E/G family 444 715 2.2E-101 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 UA74_08180 5b1a1a4d15050bc710639ee5e0785217 949 Gene3D G3DSA:2.40.50.140 358 448 1.5E-28 T 12-10-2018 UA74_08180 5b1a1a4d15050bc710639ee5e0785217 949 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 340 742 3.4E-150 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 UA74_08180 5b1a1a4d15050bc710639ee5e0785217 949 Pfam PF00575 S1 RNA binding domain 364 441 8.1E-5 T 12-10-2018 IPR003029 S1 domain GO:0003676 UA74_08180 5b1a1a4d15050bc710639ee5e0785217 949 Gene3D G3DSA:1.10.10.2480 24 90 2.7E-8 T 12-10-2018 UA74_08180 5b1a1a4d15050bc710639ee5e0785217 949 SMART SM00316 363 442 1.6E-7 T 12-10-2018 IPR022967 RNA-binding domain, S1 UA74_08180 5b1a1a4d15050bc710639ee5e0785217 949 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 23 72 9.3E-10 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal UA74_08180 5b1a1a4d15050bc710639ee5e0785217 949 SUPERFAMILY SSF50249 365 448 6.2E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF53901 31 408 3.79E-101 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00698 Acyl transferase domain 565 884 5.1E-47 T 12-10-2018 IPR014043 Acyl transferase UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00698 Acyl transferase domain 2615 2923 7.4E-82 T 12-10-2018 IPR014043 Acyl transferase UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF08659 KR domain 1715 1892 8.9E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF08659 KR domain 3454 3632 2.5E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.366.10 563 869 9.7E-162 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.366.10 2614 2923 1.3E-157 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2616 2920 1.4E-112 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 565 866 3.6E-114 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 3253 3440 1.1E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.50.11460 1209 1381 2.3E-43 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.30.70.3290 2534 2967 1.3E-157 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2023 2038 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF47336 3728 3823 1.1E-14 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 1710 1929 7.9E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1715 1894 4.6E-51 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3454 3634 2.0E-53 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.50.1820 3821 4094 4.2E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 1427 1483 2.5E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF50129 1406 1540 7.55E-32 T 12-10-2018 IPR011032 GroES-like superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF52151 561 861 4.71E-69 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF08990 Erythronolide synthase docking 2 26 2.0E-12 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.90.180.10 1390 1708 3.3E-126 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2346 2463 2.1E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 1.0E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00824 Thioesterase 3879 4092 3.7E-96 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.9E-89 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2088 2338 6.6E-85 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.50.720 1709 1961 4.8E-65 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.47.10 2079 2533 1.0E-183 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.47.10 24 476 6.2E-187 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3760 3775 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00550 Phosphopantetheine attachment site 3736 3801 1.1E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00550 Phosphopantetheine attachment site 1998 2063 2.5E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF53901 2086 2460 5.01E-100 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00829 1407 1705 4.3E-173 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF55048 700 761 2.09E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00107 Zinc-binding dehydrogenase 1546 1640 5.3E-17 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00823 Phosphopantetheine attachment site 3733 3805 6.3E-22 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00823 Phosphopantetheine attachment site 1996 2068 7.1E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF47336 1993 2103 2.49E-23 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF55048 2737 2810 1.1E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM01294 1997 2064 8.0E-5 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:1.10.1200.10 1975 2069 1.7E-33 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:1.10.1200.10 3713 3806 2.6E-25 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.30.70.3290 478 911 9.7E-162 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00825 Beta-ketoacyl synthase 2090 2516 5.1E-216 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00825 Beta-ketoacyl synthase 36 462 2.3E-219 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF00975 Thioesterase domain 3877 4091 1.5E-21 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 528 4.2E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2466 2584 2.5E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 1535 1556 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2251 2267 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.10.129.110 920 1208 1.3E-107 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.10.129.110 2975 3247 6.7E-79 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF53474 3763 4093 1.52E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 3449 3702 4.66E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 1207 1382 1.69E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF51735 1506 1644 9.69E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00826 931 1092 4.3E-73 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SMART SM00826 2986 3165 5.6E-49 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 SUPERFAMILY SSF52151 2612 2903 4.19E-65 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Gene3D G3DSA:3.40.50.720 3254 3708 4.2E-125 T 12-10-2018 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF14765 Polyketide synthase dehydratase 931 1202 1.3E-52 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16435 628ed6efc20addb554b0edce2a85beae 4096 Pfam PF14765 Polyketide synthase dehydratase 2986 3245 4.2E-34 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_04695 e4f4b3ecb9db67737b6613cb393dff1d 295 SUPERFAMILY SSF53474 39 289 1.54E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_04695 e4f4b3ecb9db67737b6613cb393dff1d 295 Gene3D G3DSA:3.40.50.1820 34 291 2.0E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_04695 e4f4b3ecb9db67737b6613cb393dff1d 295 Pfam PF12697 Alpha/beta hydrolase family 43 282 2.8E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_06575 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06575 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06575 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06575 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06575 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06575 948af2661075360f95bfb27175992848 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06575 948af2661075360f95bfb27175992848 253 Gene3D G3DSA:3.40.50.720 1 252 1.7E-75 T 12-10-2018 UA74_06575 948af2661075360f95bfb27175992848 253 SUPERFAMILY SSF51735 7 252 1.72E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_06575 948af2661075360f95bfb27175992848 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 1.5E-60 T 12-10-2018 UA74_06575 948af2661075360f95bfb27175992848 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06575 948af2661075360f95bfb27175992848 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06575 948af2661075360f95bfb27175992848 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06575 948af2661075360f95bfb27175992848 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_11875 bd66b641b831e2cd6f76a5d570d9a1c6 332 Gene3D G3DSA:3.20.20.100 3 319 3.9E-66 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_11875 bd66b641b831e2cd6f76a5d570d9a1c6 332 SUPERFAMILY SSF51430 5 319 1.18E-63 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_11875 bd66b641b831e2cd6f76a5d570d9a1c6 332 Pfam PF00248 Aldo/keto reductase family 16 317 4.0E-42 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_08510 8e395cd9664ff65499a170437adbd111 215 Pfam PF00486 Transcriptional regulatory protein, C terminal 121 192 1.7E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_08510 8e395cd9664ff65499a170437adbd111 215 Gene3D G3DSA:3.40.50.2300 1 97 4.7E-25 T 12-10-2018 UA74_08510 8e395cd9664ff65499a170437adbd111 215 SUPERFAMILY SSF52172 3 147 2.19E-28 T 12-10-2018 IPR011006 CheY-like superfamily UA74_08510 8e395cd9664ff65499a170437adbd111 215 Gene3D G3DSA:1.10.10.10 101 203 2.5E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08510 8e395cd9664ff65499a170437adbd111 215 SMART SM00448 1 88 3.8E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_08510 8e395cd9664ff65499a170437adbd111 215 Pfam PF00072 Response regulator receiver domain 2 89 5.2E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_08510 8e395cd9664ff65499a170437adbd111 215 SMART SM00862 121 193 4.8E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_22340 7514e179f359a43c261404987d551e47 167 Gene3D G3DSA:3.40.630.30 1 166 1.4E-43 T 12-10-2018 UA74_22340 7514e179f359a43c261404987d551e47 167 Pfam PF00583 Acetyltransferase (GNAT) family 41 124 4.9E-11 T 12-10-2018 IPR000182 GNAT domain UA74_22340 7514e179f359a43c261404987d551e47 167 SUPERFAMILY SSF55729 1 130 7.89E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_07095 e13b17ea78b1f0747077d8efce1d17ef 422 Gene3D G3DSA:3.65.10.10 21 230 2.1E-152 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UA74_07095 e13b17ea78b1f0747077d8efce1d17ef 422 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 416 39.411 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_07095 e13b17ea78b1f0747077d8efce1d17ef 422 Gene3D G3DSA:3.65.10.10 7 414 2.1E-152 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UA74_07095 e13b17ea78b1f0747077d8efce1d17ef 422 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 415 8.8E-163 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_07095 e13b17ea78b1f0747077d8efce1d17ef 422 SUPERFAMILY SSF55205 4 417 1.7E-126 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 UA74_07095 e13b17ea78b1f0747077d8efce1d17ef 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 1.5E-99 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 UA74_30165 1899fa9505e9ff918e04dd998ad78e2d 511 SUPERFAMILY SSF52540 14 229 5.75E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_30165 1899fa9505e9ff918e04dd998ad78e2d 511 SUPERFAMILY SSF52540 255 493 4.67E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_30165 1899fa9505e9ff918e04dd998ad78e2d 511 Pfam PF00005 ABC transporter 31 180 1.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_30165 1899fa9505e9ff918e04dd998ad78e2d 511 Pfam PF00005 ABC transporter 279 432 2.1E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_30165 1899fa9505e9ff918e04dd998ad78e2d 511 SMART SM00382 40 228 3.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_30165 1899fa9505e9ff918e04dd998ad78e2d 511 SMART SM00382 287 481 9.0E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_30165 1899fa9505e9ff918e04dd998ad78e2d 511 Gene3D G3DSA:3.40.50.300 3 238 5.7E-55 T 12-10-2018 UA74_30165 1899fa9505e9ff918e04dd998ad78e2d 511 Gene3D G3DSA:3.40.50.300 268 510 8.5E-45 T 12-10-2018 UA74_30165 1899fa9505e9ff918e04dd998ad78e2d 511 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22365 e71bcc6d2569843802e52e03fa19960a 323 Pfam PF08279 HTH domain 7 62 4.8E-14 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 UA74_22365 e71bcc6d2569843802e52e03fa19960a 323 Pfam PF13280 WYL domain 141 309 1.8E-30 T 12-10-2018 IPR026881 WYL domain UA74_22365 e71bcc6d2569843802e52e03fa19960a 323 SMART SM00420 7 59 0.0072 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_22365 e71bcc6d2569843802e52e03fa19960a 323 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_22365 e71bcc6d2569843802e52e03fa19960a 323 SUPERFAMILY SSF46785 5 62 2.59E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22365 e71bcc6d2569843802e52e03fa19960a 323 PIRSF PIRSF016838 2 317 2.4E-24 T 12-10-2018 IPR028349 Protein PafC UA74_22365 e71bcc6d2569843802e52e03fa19960a 323 Gene3D G3DSA:1.10.10.10 4 65 9.7E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 Gene3D G3DSA:2.40.50.140 1 115 2.8E-46 T 12-10-2018 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 Gene3D G3DSA:4.10.950.10 197 273 2.1E-29 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 SMART SM01382 125 253 1.1E-86 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 119 1.8E-32 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 SUPERFAMILY SSF50104 127 271 1.56E-54 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 6.8E-54 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 PIRSF PIRSF002158 3 274 2.6E-93 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 SUPERFAMILY SSF50249 3 126 5.48E-49 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 SMART SM01383 42 119 4.4E-41 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 47.172 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 Gene3D G3DSA:2.30.30.30 119 196 5.2E-32 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 UA74_02960 8ad3832c7e2332e3ce67ca1f2362842c 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 1.9E-124 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF52151 562 850 1.75E-66 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00826 3957 4121 7.9E-76 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF47336 1480 1589 5.76E-21 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF52151 3587 3877 3.92E-67 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.30.70.3290 478 910 1.4E-156 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.30.70.3290 2027 2459 4.4E-155 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF55048 3718 3782 3.66E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3224 3240 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.10.129.110 3948 4234 3.4E-108 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1508 1523 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4742 4757 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.50.720 4240 4690 3.3E-118 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:1.10.1200.10 1463 1555 9.7E-33 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1738 1754 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF55048 687 753 8.24E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF08659 KR domain 4437 4616 5.4E-56 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF08659 KR domain 1193 1371 7.9E-55 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF08659 KR domain 2695 2870 9.5E-58 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 1188 1426 1.2E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF14765 Polyketide synthase dehydratase 3957 4230 2.8E-57 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF53901 3060 3427 2.14E-104 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00823 Phosphopantetheine attachment site 2968 3040 1.3E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00823 Phosphopantetheine attachment site 1481 1553 2.4E-27 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00823 Phosphopantetheine attachment site 4715 4787 4.1E-33 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF08990 Erythronolide synthase docking 3 26 5.3E-11 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 2476 2684 7.1E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF47336 2963 3076 2.22E-24 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF53901 1572 1941 3.7E-104 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3061 3311 1.5E-87 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1575 1825 5.2E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 1.8E-86 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.50.720 2467 2951 6.6E-145 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 2692 2907 7.28E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.30.70.3290 3509 3940 3.6E-159 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 970 1179 1.46E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 4436 4637 2.46E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3319 3436 1.2E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 409 5.9E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1834 1950 2.0E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2995 3010 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM01294 4716 4783 2.7E-6 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM01294 1482 1549 3.5E-5 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM01294 2969 3036 3.2E-7 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF52151 2110 2398 1.75E-63 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:1.10.1200.10 2952 3041 7.6E-32 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:1.10.1200.10 4695 4787 1.1E-34 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00825 Beta-ketoacyl synthase 36 462 7.4E-220 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00825 Beta-ketoacyl synthase 3063 3487 1.5E-218 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00825 Beta-ketoacyl synthase 1577 2003 5.6E-216 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00550 Phosphopantetheine attachment site 2970 3036 3.4E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00550 Phosphopantetheine attachment site 1483 1546 1.1E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00550 Phosphopantetheine attachment site 4721 4783 3.4E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00698 Acyl transferase domain 3590 3910 1.1E-49 T 12-10-2018 IPR014043 Acyl transferase UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00698 Acyl transferase domain 2112 2426 1.3E-84 T 12-10-2018 IPR014043 Acyl transferase UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF00698 Acyl transferase domain 566 868 5.7E-85 T 12-10-2018 IPR014043 Acyl transferase UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.366.10 564 866 1.4E-156 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.366.10 3589 3895 3.6E-159 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.366.10 2112 2414 4.4E-155 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.47.10 3055 3503 9.5E-188 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.47.10 25 474 2.1E-187 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.47.10 1566 2022 1.3E-186 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Gene3D G3DSA:3.40.50.720 924 1447 7.0E-160 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF55048 2235 2300 2.75E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3591 3892 3.8E-116 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2114 2411 3.6E-108 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 566 863 2.3E-116 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3439 3556 3.4E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 529 3.1E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1953 2053 4.7E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF53901 29 400 4.08E-99 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF51735 4239 4415 1.75E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4437 4617 8.6E-54 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1193 1373 1.1E-43 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2695 2872 5.1E-52 T 12-10-2018 UA74_16505 70cdb7613d38c5961137a8129e68db68 4866 SUPERFAMILY SSF47336 4708 4794 5.1E-23 T 12-10-2018 IPR036736 ACP-like superfamily UA74_03145 8427a0eb9697a5320060f7883b549df4 180 SUPERFAMILY SSF64263 1 118 2.49E-45 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03145 8427a0eb9697a5320060f7883b549df4 180 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 116 1.6E-38 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03145 8427a0eb9697a5320060f7883b549df4 180 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.527 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03145 8427a0eb9697a5320060f7883b549df4 180 Gene3D G3DSA:3.90.1030.10 3 125 6.1E-43 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03145 8427a0eb9697a5320060f7883b549df4 180 Pfam PF01196 Ribosomal protein L17 20 116 3.7E-34 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_17880 7fa2775749aef3b29773151506f96833 258 Pfam PF10067 Predicted membrane protein (DUF2306) 76 225 1.2E-37 T 12-10-2018 IPR018750 Protein of unknown function DUF2306, membrane UA74_13280 fde5873098b31599474d9656af177b59 362 SMART SM00382 17 160 1.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13280 fde5873098b31599474d9656af177b59 362 SUPERFAMILY SSF52540 7 156 9.11E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13280 fde5873098b31599474d9656af177b59 362 Gene3D G3DSA:3.40.50.300 5 162 3.4E-22 T 12-10-2018 UA74_13280 fde5873098b31599474d9656af177b59 362 Pfam PF07728 AAA domain (dynein-related subfamily) 20 149 3.4E-9 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3733 3983 1.6E-90 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 553 802 7.1E-81 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2052 2302 2.2E-91 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF51735 3366 3612 3.1E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF08659 KR domain 1691 1864 1.3E-57 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF08659 KR domain 5070 5242 3.4E-53 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF08659 KR domain 3368 3540 2.0E-54 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.30.70.3290 2506 2930 2.2E-150 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF51735 4894 5056 2.44E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00826 2949 3111 3.8E-75 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00826 4618 4779 1.2E-75 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM01294 1961 2028 1.1E-4 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM01294 5341 5408 3.2E-5 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM01294 468 531 3.6E-5 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM01294 3638 3705 1.4E-5 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.30.70.3290 4178 4598 9.2E-152 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.366.10 1111 1403 2.5E-158 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.366.10 4259 4555 9.2E-152 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.366.10 96 399 2.4E-129 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.366.10 2586 2887 2.2E-150 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00823 Phosphopantetheine attachment site 5340 5412 4.8E-28 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00823 Phosphopantetheine attachment site 3637 3709 5.1E-32 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00823 Phosphopantetheine attachment site 1960 2032 2.7E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00823 Phosphopantetheine attachment site 463 535 7.8E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF52151 95 384 2.62E-60 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00698 Acyl transferase domain 1113 1417 3.3E-53 T 12-10-2018 IPR014043 Acyl transferase UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00698 Acyl transferase domain 4260 4571 5.4E-83 T 12-10-2018 IPR014043 Acyl transferase UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00698 Acyl transferase domain 97 415 1.1E-79 T 12-10-2018 IPR014043 Acyl transferase UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00698 Acyl transferase domain 2587 2903 6.0E-80 T 12-10-2018 IPR014043 Acyl transferase UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF55048 2708 2770 4.05E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3664 3679 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF14765 Polyketide synthase dehydratase 2949 3219 4.9E-55 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF14765 Polyketide synthase dehydratase 4618 4887 9.8E-54 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.30.70.3290 1027 1446 2.5E-158 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.50.720 3224 3609 6.8E-122 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.50.720 4893 5315 8.7E-120 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1987 2002 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF52151 4258 4541 2.38E-62 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF51735 1687 1907 1.89E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF51735 5068 5311 1.55E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF47336 5334 5415 8.51E-21 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 715 731 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF53901 3731 4103 4.95E-103 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF53901 549 922 1.22E-101 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF47336 458 568 2.62E-22 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF51735 3226 3356 3.74E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.10.129.110 4607 4892 8.7E-110 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.10.129.110 2938 3223 9.1E-106 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF47336 3634 3748 1.57E-24 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF52151 2585 2866 1.12E-63 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00550 Phosphopantetheine attachment site 466 531 4.0E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00550 Phosphopantetheine attachment site 1963 2028 4.9E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00550 Phosphopantetheine attachment site 5344 5407 3.7E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF00550 Phosphopantetheine attachment site 3639 3705 2.4E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF47336 1957 2067 2.62E-21 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.30.70.3290 11 433 2.4E-129 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 98 396 1.1E-92 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1113 1400 6.3E-118 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2588 2884 3.8E-109 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4261 4552 7.1E-110 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3896 3912 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:1.10.1200.10 444 536 2.9E-29 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:1.10.1200.10 3616 3709 4.3E-33 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5070 5244 1.3E-51 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1691 1866 6.9E-52 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3368 3542 3.1E-51 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.47.10 3726 4177 3.6E-189 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.47.10 2045 2497 4.0E-188 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.47.10 548 988 3.7E-180 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:3.40.50.720 1457 1937 1.4E-156 T 12-10-2018 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:1.10.1200.10 5323 5414 1.4E-31 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Gene3D G3DSA:1.10.1200.10 1943 2034 2.8E-31 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF52151 1110 1400 8.63E-73 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF55048 1236 1292 2.62E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF53901 2049 2422 4.64E-103 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2428 2547 3.4E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4109 4219 1.6E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 928 1076 5.1E-10 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF55048 4381 4443 3.27E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2215 2231 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 ProSitePatterns PS00012 Phosphopantetheine attachment site. 490 505 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5367 5382 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF51735 1505 1680 4.72E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00825 Beta-ketoacyl synthase 3735 4159 8.9E-225 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00825 Beta-ketoacyl synthase 2054 2478 7.2E-216 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SMART SM00825 Beta-ketoacyl synthase 555 977 7.1E-204 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 SUPERFAMILY SSF55048 221 285 1.44E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2310 2425 3.1E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 810 925 4.9E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_17320 1d22494964fabafd4f635c1ddbd4da33 5491 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3991 4106 2.4E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_28030 71a4d42487ba08281579ced52562ad06 444 SUPERFAMILY SSF53738 4 179 1.84E-45 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 443 44.543 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 SUPERFAMILY SSF53738 256 362 6.67E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 439 3.8E-14 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 1.3E-13 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.3E-13 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 1.3E-13 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 SUPERFAMILY SSF53738 158 254 9.03E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 Gene3D G3DSA:3.40.120.10 255 338 9.2E-70 T 12-10-2018 UA74_28030 71a4d42487ba08281579ced52562ad06 444 Gene3D G3DSA:3.30.310.50 369 444 4.0E-25 T 12-10-2018 UA74_28030 71a4d42487ba08281579ced52562ad06 444 SUPERFAMILY SSF55957 356 442 2.35E-22 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 365 6.8E-32 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 441 7.3E-181 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 Gene3D G3DSA:3.40.120.10 3 154 2.1E-46 T 12-10-2018 UA74_28030 71a4d42487ba08281579ced52562ad06 444 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 1.1E-39 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 252 9.7E-21 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_28030 71a4d42487ba08281579ced52562ad06 444 Gene3D G3DSA:3.40.120.10 172 361 9.2E-70 T 12-10-2018 UA74_00830 06833bfd330786d1b95debd18f0f03be 57 Pfam PF14013 MT0933-like antitoxin protein 9 53 7.1E-9 T 12-10-2018 IPR028037 Antitoxin Rv0909/MT0933 UA74_11720 6f052701376013f965efa41384751bab 215 SUPERFAMILY SSF56784 13 178 6.54E-42 T 12-10-2018 IPR036412 HAD-like superfamily UA74_11720 6f052701376013f965efa41384751bab 215 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 18 158 1.9E-32 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 UA74_11720 6f052701376013f965efa41384751bab 215 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 18 157 1.1E-30 T 12-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 UA74_11720 6f052701376013f965efa41384751bab 215 Gene3D G3DSA:3.40.50.1000 2 184 3.4E-43 T 12-10-2018 IPR023214 HAD superfamily UA74_11720 6f052701376013f965efa41384751bab 215 Pfam PF13242 HAD-hyrolase-like 112 176 1.1E-12 T 12-10-2018 UA74_19240 dd603946f76c0befb2c1e33647d5deae 138 SMART SM00886 2 93 5.7E-13 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel UA74_19240 dd603946f76c0befb2c1e33647d5deae 138 Pfam PF07876 Stress responsive A/B Barrel Domain 2 92 8.5E-14 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel UA74_19240 dd603946f76c0befb2c1e33647d5deae 138 SUPERFAMILY SSF54909 1 97 2.31E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_19240 dd603946f76c0befb2c1e33647d5deae 138 Gene3D G3DSA:3.30.70.100 1 92 3.0E-10 T 12-10-2018 UA74_11185 af303975c56a759970c0e874fc5a9055 521 SUPERFAMILY SSF55729 356 493 1.01E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_11185 af303975c56a759970c0e874fc5a9055 521 SUPERFAMILY SSF55021 184 248 1.26E-7 T 12-10-2018 UA74_11185 af303975c56a759970c0e874fc5a9055 521 Pfam PF00583 Acetyltransferase (GNAT) family 417 491 3.1E-8 T 12-10-2018 IPR000182 GNAT domain UA74_11185 af303975c56a759970c0e874fc5a9055 521 Pfam PF01842 ACT domain 185 231 2.0E-6 T 12-10-2018 IPR002912 ACT domain UA74_11185 af303975c56a759970c0e874fc5a9055 521 Gene3D G3DSA:3.40.630.30 361 521 8.6E-26 T 12-10-2018 UA74_11185 af303975c56a759970c0e874fc5a9055 521 Gene3D G3DSA:3.30.70.260 184 251 3.5E-6 T 12-10-2018 UA74_13800 79312d2f462bc4a6fff8817baaf920e1 96 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 87 1.3E-16 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_13800 79312d2f462bc4a6fff8817baaf920e1 96 PIRSF PIRSF032582 1 96 3.2E-31 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_13800 79312d2f462bc4a6fff8817baaf920e1 96 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 95 15.05 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_13800 79312d2f462bc4a6fff8817baaf920e1 96 Pfam PF09827 CRISPR associated protein Cas2 1 73 9.1E-19 T 12-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 UA74_13800 79312d2f462bc4a6fff8817baaf920e1 96 SUPERFAMILY SSF143430 1 86 7.46E-22 T 12-10-2018 UA74_13800 79312d2f462bc4a6fff8817baaf920e1 96 Gene3D G3DSA:3.30.70.240 1 96 5.2E-28 T 12-10-2018 UA74_26805 6f89b36d6d1b00138a28e77e9411facc 425 SUPERFAMILY SSF47384 186 261 8.24E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_26805 6f89b36d6d1b00138a28e77e9411facc 425 SMART SM00387 308 409 7.6E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_26805 6f89b36d6d1b00138a28e77e9411facc 425 SUPERFAMILY SSF55874 268 410 1.57E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_26805 6f89b36d6d1b00138a28e77e9411facc 425 Gene3D G3DSA:3.30.565.10 266 410 1.7E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_26805 6f89b36d6d1b00138a28e77e9411facc 425 Gene3D G3DSA:1.10.287.130 153 265 7.6E-14 T 12-10-2018 UA74_26805 6f89b36d6d1b00138a28e77e9411facc 425 SMART SM00388 202 266 0.002 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_26805 6f89b36d6d1b00138a28e77e9411facc 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 389 4.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_26805 6f89b36d6d1b00138a28e77e9411facc 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 357 4.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_26805 6f89b36d6d1b00138a28e77e9411facc 425 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 402 1.6E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_14025 a06cfb57f2aa6bdc362ddebe11906f69 127 Pfam PF11236 Protein of unknown function (DUF3037) 9 126 1.1E-38 T 12-10-2018 IPR021398 Protein of unknown function DUF3037 UA74_01175 176f4fda305558fa427bbdf96f8ee628 850 SMART SM00740 699 762 1.4E-6 T 12-10-2018 IPR005543 PASTA domain UA74_01175 176f4fda305558fa427bbdf96f8ee628 850 Gene3D G3DSA:3.40.710.10 291 698 1.8E-69 T 12-10-2018 UA74_01175 176f4fda305558fa427bbdf96f8ee628 850 Pfam PF00912 Transglycosylase 71 253 5.5E-59 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_01175 176f4fda305558fa427bbdf96f8ee628 850 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 622 1.3E-20 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_01175 176f4fda305558fa427bbdf96f8ee628 850 Gene3D G3DSA:3.30.10.20 703 763 3.7E-16 T 12-10-2018 UA74_01175 176f4fda305558fa427bbdf96f8ee628 850 SUPERFAMILY SSF53955 55 274 2.7E-68 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_01175 176f4fda305558fa427bbdf96f8ee628 850 Gene3D G3DSA:1.10.3810.10 59 269 8.0E-72 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_01175 176f4fda305558fa427bbdf96f8ee628 850 SUPERFAMILY SSF56601 235 696 3.09E-70 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_01175 176f4fda305558fa427bbdf96f8ee628 850 Pfam PF03793 PASTA domain 706 762 7.6E-9 T 12-10-2018 IPR005543 PASTA domain UA74_05230 839e9085c7960f359b73272ade6ba9b5 353 SUPERFAMILY SSF54631 208 332 9.22E-20 T 12-10-2018 UA74_05230 839e9085c7960f359b73272ade6ba9b5 353 SMART SM00116 285 332 5.9E-5 T 12-10-2018 IPR000644 CBS domain UA74_05230 839e9085c7960f359b73272ade6ba9b5 353 Pfam PF01595 Domain of unknown function DUF21 10 200 1.2E-33 T 12-10-2018 IPR002550 CNNM, transmembrane domain UA74_05230 839e9085c7960f359b73272ade6ba9b5 353 Gene3D G3DSA:3.10.580.10 207 335 8.5E-17 T 12-10-2018 UA74_05230 839e9085c7960f359b73272ade6ba9b5 353 Pfam PF00571 CBS domain 283 332 5.4E-7 T 12-10-2018 IPR000644 CBS domain UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 SUPERFAMILY SSF51569 1 324 6.59E-129 T 12-10-2018 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 SMART SM01004 2 322 3.8E-207 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 PIRSF PIRSF001415 1 325 1.6E-141 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 Pfam PF00490 Delta-aminolevulinic acid dehydratase 5 321 1.5E-134 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 2.8E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 2.8E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 2.8E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 2.8E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 2.8E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 2.8E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UA74_02335 f6d9c4f778c78b6fa2df9704a4466c23 325 Gene3D G3DSA:3.20.20.70 1 325 2.8E-133 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_21930 e340751b1d935748955568ffaf496639 199 SUPERFAMILY SSF48498 78 188 6.0E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_21930 e340751b1d935748955568ffaf496639 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 4.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_21930 e340751b1d935748955568ffaf496639 199 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 184 1.2E-12 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_21930 e340751b1d935748955568ffaf496639 199 SUPERFAMILY SSF46689 5 67 1.39E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_21930 e340751b1d935748955568ffaf496639 199 Gene3D G3DSA:1.10.10.60 4 54 7.2E-10 T 12-10-2018 UA74_21930 e340751b1d935748955568ffaf496639 199 Gene3D G3DSA:1.10.357.10 55 187 1.7E-19 T 12-10-2018 UA74_01600 c3ccf8559c34c22615c7f311695a67b2 178 SUPERFAMILY SSF50692 1 115 2.24E-48 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily UA74_01600 c3ccf8559c34c22615c7f311695a67b2 178 Pfam PF02261 Aspartate decarboxylase 1 114 2.4E-51 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UA74_01600 c3ccf8559c34c22615c7f311695a67b2 178 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 72.724 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UA74_01600 c3ccf8559c34c22615c7f311695a67b2 178 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 4.0E-34 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UA74_01600 c3ccf8559c34c22615c7f311695a67b2 178 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 117 1.5E-50 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UA74_01600 c3ccf8559c34c22615c7f311695a67b2 178 Gene3D G3DSA:2.40.40.20 1 124 5.7E-52 T 12-10-2018 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 386 38.326 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 6.6E-38 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Gene3D G3DSA:3.30.1330.20 218 325 6.2E-39 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Gene3D G3DSA:3.40.50.1440 1 217 3.3E-80 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.2E-35 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 PRINTS PR00423 Cell division protein FtsZ signature 95 115 9.6E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 PRINTS PR00423 Cell division protein FtsZ signature 186 208 9.6E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 PRINTS PR00423 Cell division protein FtsZ signature 209 230 9.6E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 PRINTS PR00423 Cell division protein FtsZ signature 123 144 9.6E-51 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 SUPERFAMILY SSF52490 9 205 1.01E-65 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 SMART SM00864 10 202 1.4E-108 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 SMART SM00865 204 321 4.8E-56 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 314 7.8E-127 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 SUPERFAMILY SSF55307 201 315 8.7E-43 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 UA74_09690 cadd0964e2f0d8d5fcd3a11fe057aae1 457 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 UA74_01020 3f90557745ec2fc5c5b3646ab26993f6 741 SMART SM00382 36 180 5.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01020 3f90557745ec2fc5c5b3646ab26993f6 741 SUPERFAMILY SSF52540 32 221 3.58E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01020 3f90557745ec2fc5c5b3646ab26993f6 741 Pfam PF13177 DNA polymerase III, delta subunit 19 177 1.8E-38 T 12-10-2018 UA74_01020 3f90557745ec2fc5c5b3646ab26993f6 741 Gene3D G3DSA:1.10.8.60 7 229 6.9E-93 T 12-10-2018 UA74_01020 3f90557745ec2fc5c5b3646ab26993f6 741 Gene3D G3DSA:1.20.272.10 244 366 1.3E-6 T 12-10-2018 UA74_01020 3f90557745ec2fc5c5b3646ab26993f6 741 Gene3D G3DSA:3.40.50.300 12 178 6.9E-93 T 12-10-2018 UA74_01020 3f90557745ec2fc5c5b3646ab26993f6 741 SUPERFAMILY SSF48019 246 363 5.95E-21 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 UA74_01020 3f90557745ec2fc5c5b3646ab26993f6 741 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 4 362 9.7E-112 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 UA74_01020 3f90557745ec2fc5c5b3646ab26993f6 741 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 235 364 2.3E-13 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 UA74_28125 641aa98ee3b13e1082375cda11eb0b4e 603 Gene3D G3DSA:3.40.50.12780 13 319 2.3E-49 T 12-10-2018 UA74_28125 641aa98ee3b13e1082375cda11eb0b4e 603 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_28125 641aa98ee3b13e1082375cda11eb0b4e 603 Gene3D G3DSA:3.30.300.30 470 601 4.5E-6 T 12-10-2018 UA74_28125 641aa98ee3b13e1082375cda11eb0b4e 603 Pfam PF00501 AMP-binding enzyme 26 471 5.7E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_28125 641aa98ee3b13e1082375cda11eb0b4e 603 SUPERFAMILY SSF56801 18 601 8.77E-111 T 12-10-2018 UA74_28125 641aa98ee3b13e1082375cda11eb0b4e 603 Gene3D G3DSA:3.40.50.12780 326 469 2.8E-36 T 12-10-2018 UA74_14475 d75685a07578c96e893bd364335ca53f 534 Gene3D G3DSA:3.40.710.10 44 106 4.2E-6 T 12-10-2018 UA74_14475 d75685a07578c96e893bd364335ca53f 534 Gene3D G3DSA:3.40.710.10 260 499 3.8E-58 T 12-10-2018 UA74_14475 d75685a07578c96e893bd364335ca53f 534 SUPERFAMILY SSF56601 38 483 4.54E-99 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_14475 d75685a07578c96e893bd364335ca53f 534 Gene3D G3DSA:3.50.80.20 107 192 5.1E-21 T 12-10-2018 UA74_14475 d75685a07578c96e893bd364335ca53f 534 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 66 472 6.8E-113 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_14475 d75685a07578c96e893bd364335ca53f 534 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 40 491 2.7E-137 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_14475 d75685a07578c96e893bd364335ca53f 534 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 78 97 3.1E-29 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_14475 d75685a07578c96e893bd364335ca53f 534 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 367 381 3.1E-29 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_14475 d75685a07578c96e893bd364335ca53f 534 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 382 396 3.1E-29 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_14475 d75685a07578c96e893bd364335ca53f 534 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 449 462 3.1E-29 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_14475 d75685a07578c96e893bd364335ca53f 534 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 309 331 3.1E-29 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_04855 8f7b23088476807e5834f86f1199c28d 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 7.4E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_04855 8f7b23088476807e5834f86f1199c28d 200 SUPERFAMILY SSF48498 88 185 3.56E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_04855 8f7b23088476807e5834f86f1199c28d 200 Gene3D G3DSA:1.10.357.10 18 190 4.8E-33 T 12-10-2018 UA74_04855 8f7b23088476807e5834f86f1199c28d 200 SUPERFAMILY SSF46689 16 88 4.0E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_04855 8f7b23088476807e5834f86f1199c28d 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 9.9E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_04855 8f7b23088476807e5834f86f1199c28d 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 9.9E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_17870 26fb8ac7ca84fd1c7de16f9641580376 344 Gene3D G3DSA:1.10.260.40 4 69 1.1E-22 T 12-10-2018 UA74_17870 26fb8ac7ca84fd1c7de16f9641580376 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 4.2E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_17870 26fb8ac7ca84fd1c7de16f9641580376 344 SMART SM00354 12 82 3.8E-24 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_17870 26fb8ac7ca84fd1c7de16f9641580376 344 Pfam PF13377 Periplasmic binding protein-like domain 178 339 2.8E-35 T 12-10-2018 UA74_17870 26fb8ac7ca84fd1c7de16f9641580376 344 Gene3D G3DSA:3.40.50.2300 70 156 6.4E-13 T 12-10-2018 UA74_17870 26fb8ac7ca84fd1c7de16f9641580376 344 SUPERFAMILY SSF47413 12 70 1.17E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_17870 26fb8ac7ca84fd1c7de16f9641580376 344 Gene3D G3DSA:3.40.50.2300 164 340 1.5E-51 T 12-10-2018 UA74_17870 26fb8ac7ca84fd1c7de16f9641580376 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 12-10-2018 UA74_17870 26fb8ac7ca84fd1c7de16f9641580376 344 SUPERFAMILY SSF53822 72 341 1.04E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF00698 Acyl transferase domain 531 791 1.6E-37 T 12-10-2018 IPR014043 Acyl transferase UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF00550 Phosphopantetheine attachment site 976 1039 2.6E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 531 850 2.3E-73 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:3.30.70.250 650 710 2.3E-122 T 12-10-2018 UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 269 386 4.3E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:3.30.70.3290 451 845 2.3E-122 T 12-10-2018 UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 SMART SM00823 Phosphopantetheine attachment site 974 1043 2.3E-6 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:3.40.47.10 9 438 6.9E-161 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 SUPERFAMILY SSF47336 967 1039 1.44E-19 T 12-10-2018 IPR036736 ACP-like superfamily UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 SUPERFAMILY SSF53901 10 434 2.21E-81 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 389 498 1.4E-19 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 SMART SM00825 Beta-ketoacyl synthase 13 438 7.0E-170 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 SUPERFAMILY SSF52151 528 810 3.66E-54 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 174 190 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:3.40.366.10 527 818 2.3E-122 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Gene3D G3DSA:1.10.1200.10 957 1045 1.4E-26 T 12-10-2018 IPR036736 ACP-like superfamily UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 260 6.6E-68 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_06495 32369ccf2eab27a4c4041fdae9ec3354 1050 ProSitePatterns PS00012 Phosphopantetheine attachment site. 998 1013 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 237 269 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 Pfam PF00815 Histidinol dehydrogenase 22 435 8.3E-155 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 259 278 4.6E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 4.6E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 4.6E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 237 258 4.6E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 4.6E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 4.6E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 4.6E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 PRINTS PR00083 Histidinol dehydrogenase signature 208 233 4.6E-83 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 Gene3D G3DSA:3.40.50.1980 29 236 1.5E-60 T 12-10-2018 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 436 38.312 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 PIRSF PIRSF000099 1 439 8.5E-149 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 SUPERFAMILY SSF53720 25 436 5.49E-69 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 Gene3D G3DSA:3.40.50.1980 237 380 1.1E-48 T 12-10-2018 UA74_09885 44dc0c1f7a4f58f739ddde9e5629859f 440 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 435 3.4E-139 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UA74_15075 b9fcd9681854fb658948630e005b6753 314 Pfam PF01814 Hemerythrin HHE cation binding domain 165 306 2.7E-15 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 UA74_15075 b9fcd9681854fb658948630e005b6753 314 Gene3D G3DSA:2.30.110.10 4 144 2.5E-51 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_15075 b9fcd9681854fb658948630e005b6753 314 Gene3D G3DSA:1.20.120.520 157 310 5.3E-21 T 12-10-2018 UA74_15075 b9fcd9681854fb658948630e005b6753 314 Pfam PF04075 F420H(2)-dependent quinone reductase 22 143 1.4E-44 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_15075 b9fcd9681854fb658948630e005b6753 314 SUPERFAMILY SSF50475 36 146 6.54E-5 T 12-10-2018 UA74_15075 b9fcd9681854fb658948630e005b6753 314 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 32 143 1.5E-33 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 11 471 8.3E-200 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 174 9.5E-49 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 259 271 - T 12-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 PIRSF PIRSF000109 4 479 5.7E-195 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 Gene3D G3DSA:3.40.50.720 3 185 3.7E-53 T 12-10-2018 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 Gene3D G3DSA:1.10.1040.10 186 438 3.1E-98 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 SMART SM01350 184 471 5.6E-197 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 SUPERFAMILY SSF51735 9 182 4.56E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 SUPERFAMILY SSF48179 182 472 1.08E-115 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 184 470 8.5E-120 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 9 32 5.2E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 173 201 5.2E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 360 382 5.2E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 255 282 5.2E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 72 101 5.2E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 125 150 5.2E-80 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_21295 a57f4331d1061e91bdff74d581d9a9b6 479 Gene3D G3DSA:1.20.5.320 439 472 1.0E-18 T 12-10-2018 UA74_04635 bd2d3bf188b2a3d20534890febdfb541 392 Gene3D G3DSA:2.40.50.940 223 381 3.0E-28 T 12-10-2018 UA74_04635 bd2d3bf188b2a3d20534890febdfb541 392 Pfam PF00005 ABC transporter 21 162 6.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_04635 bd2d3bf188b2a3d20534890febdfb541 392 SUPERFAMILY SSF52540 4 242 1.5E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04635 bd2d3bf188b2a3d20534890febdfb541 392 Gene3D G3DSA:2.40.50.140 287 372 3.0E-28 T 12-10-2018 UA74_04635 bd2d3bf188b2a3d20534890febdfb541 392 SMART SM00382 29 212 1.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_04635 bd2d3bf188b2a3d20534890febdfb541 392 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_04635 bd2d3bf188b2a3d20534890febdfb541 392 SUPERFAMILY SSF50331 237 388 2.75E-20 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UA74_04635 bd2d3bf188b2a3d20534890febdfb541 392 Gene3D G3DSA:3.40.50.300 4 222 4.0E-64 T 12-10-2018 UA74_10695 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:3.40.50.300 26 272 1.6E-73 T 12-10-2018 UA74_10695 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:3.40.50.300 308 443 2.8E-51 T 12-10-2018 UA74_10695 f4dadea4551594035f80170df0a36eca 725 Pfam PF02151 UvrB/uvrC motif 682 715 1.9E-6 T 12-10-2018 IPR001943 UVR domain GO:0005515 UA74_10695 f4dadea4551594035f80170df0a36eca 725 SUPERFAMILY SSF52540 63 608 7.36E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10695 f4dadea4551594035f80170df0a36eca 725 Pfam PF00271 Helicase conserved C-terminal domain 471 573 2.5E-17 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_10695 f4dadea4551594035f80170df0a36eca 725 SMART SM00487 39 455 2.4E-24 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_10695 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:3.40.50.300 444 625 1.2E-46 T 12-10-2018 UA74_10695 f4dadea4551594035f80170df0a36eca 725 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 34 713 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 UA74_10695 f4dadea4551594035f80170df0a36eca 725 Gene3D G3DSA:4.10.860.10 665 718 4.6E-7 T 12-10-2018 UA74_10695 f4dadea4551594035f80170df0a36eca 725 SUPERFAMILY SSF46600 670 716 4.18E-10 T 12-10-2018 IPR036876 UVR domain superfamily UA74_10695 f4dadea4551594035f80170df0a36eca 725 Pfam PF04851 Type III restriction enzyme, res subunit 45 149 6.0E-8 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_10695 f4dadea4551594035f80170df0a36eca 725 Hamap MF_00204 UvrABC system protein B [uvrB]. 33 715 42.573 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 UA74_10695 f4dadea4551594035f80170df0a36eca 725 Pfam PF12344 Ultra-violet resistance protein B 581 622 3.0E-20 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain UA74_10695 f4dadea4551594035f80170df0a36eca 725 SMART SM00490 489 575 3.2E-17 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_10695 f4dadea4551594035f80170df0a36eca 725 SUPERFAMILY SSF52540 35 444 3.17E-130 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21670 6f18aa18f2cd7ed0700b0fef802dc120 355 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 70 347 1.5E-84 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UA74_21670 6f18aa18f2cd7ed0700b0fef802dc120 355 Pfam PF01409 tRNA synthetases class II core domain (F) 109 348 4.5E-96 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 UA74_21670 6f18aa18f2cd7ed0700b0fef802dc120 355 Gene3D G3DSA:3.30.930.10 25 353 4.7E-101 T 12-10-2018 UA74_21670 6f18aa18f2cd7ed0700b0fef802dc120 355 SUPERFAMILY SSF55681 109 348 4.97E-73 T 12-10-2018 UA74_21670 6f18aa18f2cd7ed0700b0fef802dc120 355 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 103 5.6E-15 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 UA74_21670 6f18aa18f2cd7ed0700b0fef802dc120 355 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 351 43.767 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 UA74_21670 6f18aa18f2cd7ed0700b0fef802dc120 355 SUPERFAMILY SSF46589 31 115 3.92E-14 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 UA74_05595 6434b00d669e59eeb758082c6f4ebd72 274 SUPERFAMILY SSF48256 4 251 1.7E-48 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 UA74_05595 6434b00d669e59eeb758082c6f4ebd72 274 Gene3D G3DSA:1.10.230.10 110 218 4.7E-29 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain UA74_05595 6434b00d669e59eeb758082c6f4ebd72 274 Gene3D G3DSA:1.10.580.10 15 59 6.2E-7 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_05595 6434b00d669e59eeb758082c6f4ebd72 274 Pfam PF00285 Citrate synthase, C-terminal domain 55 246 3.8E-27 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_05595 6434b00d669e59eeb758082c6f4ebd72 274 Pfam PF00285 Citrate synthase, C-terminal domain 14 60 5.5E-6 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_05595 6434b00d669e59eeb758082c6f4ebd72 274 Gene3D G3DSA:1.10.580.10 60 244 4.7E-29 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_08775 5fad602b00387102a85b513e47efee38 227 SMART SM00862 146 222 2.2E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_08775 5fad602b00387102a85b513e47efee38 227 Pfam PF00072 Response regulator receiver domain 5 112 6.2E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_08775 5fad602b00387102a85b513e47efee38 227 SMART SM00448 2 112 1.3E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_08775 5fad602b00387102a85b513e47efee38 227 SUPERFAMILY SSF52172 3 176 3.13E-38 T 12-10-2018 IPR011006 CheY-like superfamily UA74_08775 5fad602b00387102a85b513e47efee38 227 Gene3D G3DSA:1.10.10.10 125 226 4.3E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08775 5fad602b00387102a85b513e47efee38 227 Gene3D G3DSA:3.40.50.2300 2 124 2.4E-33 T 12-10-2018 UA74_08775 5fad602b00387102a85b513e47efee38 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 6.9E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 SUPERFAMILY SSF55347 139 309 1.44E-50 T 12-10-2018 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 Pfam PF00742 Homoserine dehydrogenase 139 322 3.0E-65 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 185 207 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 PIRSF PIRSF000098 6 433 2.2E-153 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 SUPERFAMILY SSF51735 7 160 1.71E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 Gene3D G3DSA:3.40.50.720 9 341 2.9E-141 T 12-10-2018 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 SUPERFAMILY SSF55021 352 425 7.45E-11 T 12-10-2018 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 Gene3D G3DSA:3.30.360.10 138 349 2.9E-141 T 12-10-2018 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 15 131 8.9E-25 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 Gene3D G3DSA:3.30.70.260 350 421 2.9E-141 T 12-10-2018 UA74_06970 cbdd8107066d9eac14fd88b7237bb303 435 Pfam PF01842 ACT domain 357 418 1.2E-8 T 12-10-2018 IPR002912 ACT domain UA74_00095 0d1466fad9c93e00f2ef48b26b5335bb 88 Pfam PF06781 Cell division protein CrgA 1 88 3.4E-38 T 12-10-2018 IPR009619 Cell division protein CrgA UA74_00095 0d1466fad9c93e00f2ef48b26b5335bb 88 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 88 25.446 T 12-10-2018 IPR009619 Cell division protein CrgA UA74_18750 8213dd5ad96c8be4549f1ef17dc75deb 247 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 223 7.0E-26 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_18750 8213dd5ad96c8be4549f1ef17dc75deb 247 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 129 3.1E-20 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_18750 8213dd5ad96c8be4549f1ef17dc75deb 247 SUPERFAMILY SSF109854 2 136 9.77E-10 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_18750 8213dd5ad96c8be4549f1ef17dc75deb 247 Pfam PF07398 MDMPI C-terminal domain 144 238 1.9E-13 T 12-10-2018 IPR010872 MDMPI C-terminal UA74_24210 77aff6e138a50ccaaf9b9c48e84e6803 690 Pfam PF08533 Beta-galactosidase C-terminal domain 622 683 2.0E-6 T 12-10-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_24210 77aff6e138a50ccaaf9b9c48e84e6803 690 SUPERFAMILY SSF51445 15 377 1.28E-111 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_24210 77aff6e138a50ccaaf9b9c48e84e6803 690 Gene3D G3DSA:3.20.20.80 5 399 1.8E-138 T 12-10-2018 UA74_24210 77aff6e138a50ccaaf9b9c48e84e6803 690 SUPERFAMILY SSF52317 406 610 6.1E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_24210 77aff6e138a50ccaaf9b9c48e84e6803 690 Pfam PF02449 Beta-galactosidase 25 393 2.5E-150 T 12-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_24210 77aff6e138a50ccaaf9b9c48e84e6803 690 Gene3D G3DSA:3.40.50.880 404 614 5.4E-61 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_24210 77aff6e138a50ccaaf9b9c48e84e6803 690 PIRSF PIRSF001084 13 685 4.7E-262 T 12-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_24210 77aff6e138a50ccaaf9b9c48e84e6803 690 Pfam PF08532 Beta-galactosidase trimerisation domain 407 610 8.3E-62 T 12-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_28040 5ffa7203a778b4140c8b7adf547f4b54 147 SUPERFAMILY SSF52161 4 142 6.8E-59 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 UA74_28040 5ffa7203a778b4140c8b7adf547f4b54 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 1.1E-60 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_28040 5ffa7203a778b4140c8b7adf547f4b54 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 12-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 UA74_28040 5ffa7203a778b4140c8b7adf547f4b54 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 143 28.709 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UA74_28040 5ffa7203a778b4140c8b7adf547f4b54 147 Pfam PF00572 Ribosomal protein L13 15 138 9.4E-55 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UA74_28040 5ffa7203a778b4140c8b7adf547f4b54 147 PIRSF PIRSF002181 2 147 1.5E-50 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UA74_28040 5ffa7203a778b4140c8b7adf547f4b54 147 Gene3D G3DSA:3.90.1180.10 1 142 1.2E-60 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 UA74_20735 b47f27fedbfc24e79334a398df1689c8 522 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 12 480 3.4E-110 T 12-10-2018 IPR011749 Conserved hypothetical protein CHP02243 UA74_20735 b47f27fedbfc24e79334a398df1689c8 522 Pfam PF04865 Baseplate J-like protein 258 438 2.2E-10 T 12-10-2018 IPR006949 Baseplate protein J-like UA74_05525 29b46185bc35dd55d09e70d05a03a5e4 314 Pfam PF03466 LysR substrate binding domain 96 296 2.3E-14 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_05525 29b46185bc35dd55d09e70d05a03a5e4 314 Gene3D G3DSA:3.40.190.10 166 271 5.2E-20 T 12-10-2018 UA74_05525 29b46185bc35dd55d09e70d05a03a5e4 314 Gene3D G3DSA:3.40.190.10 97 288 5.2E-20 T 12-10-2018 UA74_05525 29b46185bc35dd55d09e70d05a03a5e4 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 5.4E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_05525 29b46185bc35dd55d09e70d05a03a5e4 314 Gene3D G3DSA:1.10.10.10 1 88 5.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_05525 29b46185bc35dd55d09e70d05a03a5e4 314 SUPERFAMILY SSF53850 97 297 4.78E-17 T 12-10-2018 UA74_05525 29b46185bc35dd55d09e70d05a03a5e4 314 SUPERFAMILY SSF46785 6 87 8.52E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20885 33831c06c8fada72f9b9ddf53beeec72 1009 Pfam PF00656 Caspase domain 19 213 6.3E-13 T 12-10-2018 UA74_20885 33831c06c8fada72f9b9ddf53beeec72 1009 SUPERFAMILY SSF52129 15 216 1.06E-17 T 12-10-2018 IPR029030 Caspase-like domain superfamily UA74_20885 33831c06c8fada72f9b9ddf53beeec72 1009 Gene3D G3DSA:3.40.50.1460 8 205 2.0E-19 T 12-10-2018 UA74_24655 94f6a4f172d2ee3fb1a1a27cc42c949d 189 SUPERFAMILY SSF55729 47 178 1.08E-14 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_24655 94f6a4f172d2ee3fb1a1a27cc42c949d 189 Gene3D G3DSA:3.40.630.30 24 174 1.4E-14 T 12-10-2018 UA74_24655 94f6a4f172d2ee3fb1a1a27cc42c949d 189 Pfam PF00583 Acetyltransferase (GNAT) family 97 163 5.7E-7 T 12-10-2018 IPR000182 GNAT domain UA74_13500 319729fadc0be9b816bbb575753e8bb7 292 SMART SM00382 42 234 1.0E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13500 319729fadc0be9b816bbb575753e8bb7 292 Pfam PF00005 ABC transporter 34 186 1.1E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13500 319729fadc0be9b816bbb575753e8bb7 292 Gene3D G3DSA:3.40.50.300 12 259 2.5E-51 T 12-10-2018 UA74_13500 319729fadc0be9b816bbb575753e8bb7 292 SUPERFAMILY SSF52540 16 257 3.48E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13500 319729fadc0be9b816bbb575753e8bb7 292 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_05085 747d953afc1a0aebae2375b81a0ae638 382 Gene3D G3DSA:3.40.50.2000 169 354 7.6E-19 T 12-10-2018 UA74_05085 747d953afc1a0aebae2375b81a0ae638 382 Gene3D G3DSA:3.40.50.2000 30 370 7.6E-19 T 12-10-2018 UA74_05085 747d953afc1a0aebae2375b81a0ae638 382 SUPERFAMILY SSF53756 21 372 1.26E-26 T 12-10-2018 UA74_05085 747d953afc1a0aebae2375b81a0ae638 382 Pfam PF13692 Glycosyl transferases group 1 204 336 4.9E-11 T 12-10-2018 UA74_11000 ffa924a8fa707e0531d800fd48508f1c 422 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 251 1.1E-49 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_11000 ffa924a8fa707e0531d800fd48508f1c 422 SUPERFAMILY SSF53901 2 256 3.93E-61 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11000 ffa924a8fa707e0531d800fd48508f1c 422 Gene3D G3DSA:3.40.47.10 263 420 1.4E-46 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11000 ffa924a8fa707e0531d800fd48508f1c 422 Gene3D G3DSA:3.40.47.10 1 259 1.5E-70 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11000 ffa924a8fa707e0531d800fd48508f1c 422 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 159 175 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_11000 ffa924a8fa707e0531d800fd48508f1c 422 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 373 9.0E-35 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_11000 ffa924a8fa707e0531d800fd48508f1c 422 SMART SM00825 Beta-ketoacyl synthase 5 407 1.0E-13 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_11000 ffa924a8fa707e0531d800fd48508f1c 422 SUPERFAMILY SSF53901 219 416 4.37E-65 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_27885 fa453312e82039c724320383a141fd48 330 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 49 95 1.1E-9 T 12-10-2018 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region UA74_05995 6f506590e93a37a695ba87540d9b0cde 581 Gene3D G3DSA:3.40.50.300 7 319 1.3E-9 T 12-10-2018 UA74_05995 6f506590e93a37a695ba87540d9b0cde 581 Pfam PF10088 Uncharacterised protein conserved in bacteria (DUF2326) 446 581 1.3E-34 T 12-10-2018 IPR018760 Protein of unknown function DUF2326 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 Gene3D G3DSA:3.30.930.10 1 245 5.7E-91 T 12-10-2018 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 Pfam PF01411 tRNA synthetases class II (A) 5 562 7.8E-194 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 SMART SM00863 660 704 1.2E-18 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 3.7E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 3.7E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 3.7E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 3.7E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 3.7E-26 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 868 8.9E-238 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 Gene3D G3DSA:3.10.310.40 773 886 1.8E-18 T 12-10-2018 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 660 704 7.7E-16 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 SUPERFAMILY SSF101353 249 442 2.09E-55 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 Gene3D G3DSA:3.30.980.10 571 705 4.2E-35 T 12-10-2018 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 SUPERFAMILY SSF50447 460 559 7.77E-17 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 SUPERFAMILY SSF55186 559 719 3.79E-40 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 Gene3D G3DSA:2.40.30.130 471 559 9.3E-10 T 12-10-2018 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 SUPERFAMILY SSF55681 3 248 5.47E-87 T 12-10-2018 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 Pfam PF02272 DHHA1 domain 740 883 4.2E-17 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 889 162.815 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 UA74_12045 0f4777032937edd9fa73cb2a2bbca4d0 892 Gene3D G3DSA:3.30.54.20 631 685 4.2E-35 T 12-10-2018 UA74_29150 663f8a7b16b2e5c0705943884400e193 101 SUPERFAMILY SSF49478 26 78 5.49E-6 T 12-10-2018 UA74_29150 663f8a7b16b2e5c0705943884400e193 101 Pfam PF07210 Protein of unknown function (DUF1416) 4 99 2.1E-35 T 12-10-2018 IPR010814 Protein of unknown function DUF1416 UA74_13325 2c372f384a02810f784e7291540d0c71 361 SUPERFAMILY SSF50129 7 187 9.13E-42 T 12-10-2018 IPR011032 GroES-like superfamily UA74_13325 2c372f384a02810f784e7291540d0c71 361 SMART SM00829 17 353 1.1E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_13325 2c372f384a02810f784e7291540d0c71 361 Pfam PF00107 Zinc-binding dehydrogenase 190 314 1.3E-14 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_13325 2c372f384a02810f784e7291540d0c71 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 74 88 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_13325 2c372f384a02810f784e7291540d0c71 361 Gene3D G3DSA:3.40.50.720 172 306 1.4E-72 T 12-10-2018 UA74_13325 2c372f384a02810f784e7291540d0c71 361 SUPERFAMILY SSF51735 153 314 2.89E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_13325 2c372f384a02810f784e7291540d0c71 361 Gene3D G3DSA:3.90.180.10 23 341 1.4E-72 T 12-10-2018 UA74_13325 2c372f384a02810f784e7291540d0c71 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 148 7.5E-25 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_16225 bb569a22a556ae8740390174131dc716 209 SUPERFAMILY SSF54001 84 208 1.08E-36 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UA74_16225 bb569a22a556ae8740390174131dc716 209 Pfam PF00877 NlpC/P60 family 99 193 5.1E-26 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UA74_16225 bb569a22a556ae8740390174131dc716 209 Pfam PF01464 Transglycosylase SLT domain 1 74 1.1E-4 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 UA74_16225 bb569a22a556ae8740390174131dc716 209 Gene3D G3DSA:3.90.1720.10 54 206 2.0E-44 T 12-10-2018 UA74_16225 bb569a22a556ae8740390174131dc716 209 SUPERFAMILY SSF53955 1 74 6.0E-8 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_22950 d9876c137d8058ae1eae176832f5ff74 897 Pfam PF00672 HAMP domain 344 408 9.6E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_22950 d9876c137d8058ae1eae176832f5ff74 897 SUPERFAMILY SSF55874 511 636 3.93E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_22950 d9876c137d8058ae1eae176832f5ff74 897 Pfam PF08376 Nitrate and nitrite sensing 65 294 9.5E-22 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein UA74_22950 d9876c137d8058ae1eae176832f5ff74 897 Gene3D G3DSA:3.30.565.10 490 643 3.7E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_22950 d9876c137d8058ae1eae176832f5ff74 897 SMART SM00387 524 637 2.4E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_22950 d9876c137d8058ae1eae176832f5ff74 897 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 528 634 2.8E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_14800 23ad21ba12229bb8e1e9080980bcd093 437 Pfam PF07690 Major Facilitator Superfamily 284 418 3.5E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_14800 23ad21ba12229bb8e1e9080980bcd093 437 Pfam PF07690 Major Facilitator Superfamily 45 272 3.4E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_14800 23ad21ba12229bb8e1e9080980bcd093 437 SUPERFAMILY SSF103473 41 422 1.7E-36 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_14800 23ad21ba12229bb8e1e9080980bcd093 437 Gene3D G3DSA:1.20.1250.20 37 423 9.8E-35 T 12-10-2018 UA74_05295 8fa414bf363f5d9aba73f0f00084697e 295 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 163 4.2E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_05295 8fa414bf363f5d9aba73f0f00084697e 295 Pfam PF04542 Sigma-70 region 2 15 79 3.5E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_05295 8fa414bf363f5d9aba73f0f00084697e 295 Gene3D G3DSA:1.10.1740.10 1 103 5.1E-16 T 12-10-2018 UA74_05295 8fa414bf363f5d9aba73f0f00084697e 295 SUPERFAMILY SSF88659 94 163 4.8E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_05295 8fa414bf363f5d9aba73f0f00084697e 295 Pfam PF08281 Sigma-70, region 4 106 157 5.3E-6 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_05295 8fa414bf363f5d9aba73f0f00084697e 295 SUPERFAMILY SSF88946 2 84 7.06E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_05295 8fa414bf363f5d9aba73f0f00084697e 295 Gene3D G3DSA:1.10.10.10 104 169 5.0E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_09075 436ce5a3235e6e0672b473684af6b775 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 321 8.1E-44 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 Gene3D G3DSA:3.50.50.60 4 330 3.1E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09075 436ce5a3235e6e0672b473684af6b775 462 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 2 458 3.6E-197 T 12-10-2018 IPR017817 Mycothione reductase MetaCyc: PWY-6421 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 SUPERFAMILY SSF51905 2 316 2.27E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 2.9E-40 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 2.9E-40 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 2.9E-40 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.9E-40 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 2.9E-40 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 2.9E-40 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 2.9E-40 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 Gene3D G3DSA:3.30.390.30 344 460 1.3E-34 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 Gene3D G3DSA:3.50.50.60 153 274 3.1E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09075 436ce5a3235e6e0672b473684af6b775 462 SUPERFAMILY SSF55424 342 456 1.34E-31 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PIRSF PIRSF000350 1 449 2.7E-83 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 9.2E-23 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 9.2E-23 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 9.2E-23 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 9.2E-23 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.2E-23 T 12-10-2018 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 453 2.2E-26 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_09075 436ce5a3235e6e0672b473684af6b775 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UA74_29070 98aca516ed485c093be7fc42b3b10ae6 308 Pfam PF00990 Diguanylate cyclase, GGDEF domain 115 277 6.4E-32 T 12-10-2018 IPR000160 GGDEF domain UA74_29070 98aca516ed485c093be7fc42b3b10ae6 308 Gene3D G3DSA:3.30.70.270 100 283 2.7E-46 T 12-10-2018 UA74_29070 98aca516ed485c093be7fc42b3b10ae6 308 SMART SM00267 103 282 1.6E-41 T 12-10-2018 IPR000160 GGDEF domain UA74_29070 98aca516ed485c093be7fc42b3b10ae6 308 SUPERFAMILY SSF55073 119 283 2.59E-38 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_29070 98aca516ed485c093be7fc42b3b10ae6 308 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 111 282 1.4E-39 T 12-10-2018 IPR000160 GGDEF domain UA74_22325 f3df40b22091f69ecd564fa63e70a5a0 381 Pfam PF02803 Thiolase, C-terminal domain 253 346 1.1E-11 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UA74_22325 f3df40b22091f69ecd564fa63e70a5a0 381 Gene3D G3DSA:3.40.47.10 1 378 4.5E-112 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_22325 f3df40b22091f69ecd564fa63e70a5a0 381 SUPERFAMILY SSF53901 234 364 6.15E-31 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_22325 f3df40b22091f69ecd564fa63e70a5a0 381 SUPERFAMILY SSF53901 4 220 1.25E-43 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_22325 f3df40b22091f69ecd564fa63e70a5a0 381 Pfam PF00108 Thiolase, N-terminal domain 5 213 1.2E-17 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UA74_22325 f3df40b22091f69ecd564fa63e70a5a0 381 ProSitePatterns PS00737 Thiolases signature 2. 313 329 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 UA74_22325 f3df40b22091f69ecd564fa63e70a5a0 381 PIRSF PIRSF000429 1 367 6.7E-58 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 41 284 7.1E-88 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 Pfam PF00557 Metallopeptidase family M24 48 276 1.2E-50 T 12-10-2018 IPR000994 Peptidase M24 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 1.4E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 1.4E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.4E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 1.4E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 Gene3D G3DSA:3.90.230.10 3 285 1.9E-114 T 12-10-2018 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 39.463 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_09035 bbe9578b48d5e0116c7c63884d92b424 285 SUPERFAMILY SSF55920 4 283 5.23E-89 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 3.0E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 3.0E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 3.0E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00412 Epoxide hydrolase signature 224 240 1.4E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00412 Epoxide hydrolase signature 100 113 1.4E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00412 Epoxide hydrolase signature 257 279 1.4E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 PRINTS PR00412 Epoxide hydrolase signature 45 60 1.4E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 Pfam PF00561 alpha/beta hydrolase fold 20 269 6.7E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 SUPERFAMILY SSF53474 2 282 3.13E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15440 200a6b5bdbd877c3a164439fccf0905a 286 Gene3D G3DSA:3.40.50.1820 1 283 5.3E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 SMART SM00116 118 166 6.4E-7 T 12-10-2018 IPR000644 CBS domain UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 SMART SM00116 179 227 2.4E-7 T 12-10-2018 IPR000644 CBS domain UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 PIRSF PIRSF000130 22 515 4.9E-197 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 30 501 1.0E-152 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 317 329 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 SMART SM01240 29 501 2.6E-301 T 12-10-2018 UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 Pfam PF00571 CBS domain 115 162 4.6E-8 T 12-10-2018 IPR000644 CBS domain UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 Pfam PF00571 CBS domain 171 224 1.2E-6 T 12-10-2018 IPR000644 CBS domain UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 Gene3D G3DSA:3.20.20.70 22 514 1.7E-204 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 SUPERFAMILY SSF51412 25 505 2.62E-113 T 12-10-2018 UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 30 514 81.996 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 30 483 3.8E-179 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 UA74_27875 52ee354e30df2651d3b1fc7373efb331 515 SUPERFAMILY SSF54631 115 224 1.52E-28 T 12-10-2018 UA74_08890 5368f7079fe35ee37706f6eae0f669ec 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 336 1.4E-13 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_08890 5368f7079fe35ee37706f6eae0f669ec 343 Gene3D G3DSA:3.40.50.300 1 342 3.4E-88 T 12-10-2018 UA74_08890 5368f7079fe35ee37706f6eae0f669ec 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 317 9.9E-14 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_08890 5368f7079fe35ee37706f6eae0f669ec 343 SUPERFAMILY SSF52540 4 251 2.47E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08890 5368f7079fe35ee37706f6eae0f669ec 343 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_08890 5368f7079fe35ee37706f6eae0f669ec 343 Pfam PF00005 ABC transporter 28 180 2.7E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_08890 5368f7079fe35ee37706f6eae0f669ec 343 SMART SM00382 36 230 1.4E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 Pfam PF00072 Response regulator receiver domain 3 113 2.6E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 SUPERFAMILY SSF52172 2 134 2.99E-16 T 12-10-2018 IPR011006 CheY-like superfamily UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 Gene3D G3DSA:3.40.50.12740 1 214 1.5E-41 T 12-10-2018 UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 SMART SM00421 148 211 1.6E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 SMART SM00448 1 120 8.9E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 SUPERFAMILY SSF46894 133 200 8.84E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 197 9.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_21435 4fc5455a10ada86d9f05e7e0382564c0 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05585 b365c042623161730392babe2ab64d46 408 SMART SM00530 9 64 9.8E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_05585 b365c042623161730392babe2ab64d46 408 Gene3D G3DSA:1.10.260.40 2 65 7.1E-10 T 12-10-2018 UA74_05585 b365c042623161730392babe2ab64d46 408 Pfam PF13560 Helix-turn-helix domain 7 62 5.6E-9 T 12-10-2018 UA74_05585 b365c042623161730392babe2ab64d46 408 SUPERFAMILY SSF47413 5 64 4.79E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_05585 b365c042623161730392babe2ab64d46 408 Gene3D G3DSA:1.25.40.10 131 391 6.9E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_14045 96d489292d0cffb749afb366d7594592 153 SUPERFAMILY SSF54427 3 113 2.68E-11 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_14045 96d489292d0cffb749afb366d7594592 153 Pfam PF12680 SnoaL-like domain 3 104 3.5E-8 T 12-10-2018 IPR037401 SnoaL-like domain UA74_14045 96d489292d0cffb749afb366d7594592 153 Gene3D G3DSA:3.10.450.50 1 117 1.1E-16 T 12-10-2018 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 Gene3D G3DSA:3.40.640.10 89 382 9.6E-96 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 Gene3D G3DSA:3.90.1150.10 383 483 2.4E-24 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 Gene3D G3DSA:1.20.1340.10 8 88 3.1E-26 T 12-10-2018 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 36 53 2.6E-54 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 13 32 2.6E-54 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 80 99 2.6E-54 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 54 73 2.6E-54 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 120 139 2.6E-54 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 355 370 2.6E-54 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 398 417 2.6E-54 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 101 119 2.6E-54 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 145 165 2.6E-54 T 12-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 SUPERFAMILY SSF53383 8 481 8.82E-133 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 42 416 6.9E-101 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 UA74_21300 d1a5c3a92dab815b011e84dec1045ded 483 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 299 320 - T 12-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 UA74_11300 1416e4f0319b375a04beb38cdc021493 317 SUPERFAMILY SSF52540 3 224 1.95E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11300 1416e4f0319b375a04beb38cdc021493 317 SMART SM00382 29 211 8.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_11300 1416e4f0319b375a04beb38cdc021493 317 Gene3D G3DSA:3.40.50.300 2 233 1.9E-66 T 12-10-2018 UA74_11300 1416e4f0319b375a04beb38cdc021493 317 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_11300 1416e4f0319b375a04beb38cdc021493 317 Pfam PF00005 ABC transporter 20 163 1.0E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_11300 1416e4f0319b375a04beb38cdc021493 317 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 305 2.2E-102 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_11300 1416e4f0319b375a04beb38cdc021493 317 Pfam PF13732 Domain of unknown function (DUF4162) 217 304 7.8E-7 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 UA74_29160 8836d68ce467b6dc033614a00b0b60dd 283 Gene3D G3DSA:3.30.470.10 2 112 2.5E-31 T 12-10-2018 UA74_29160 8836d68ce467b6dc033614a00b0b60dd 283 SUPERFAMILY SSF56752 5 278 1.31E-56 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 UA74_29160 8836d68ce467b6dc033614a00b0b60dd 283 Gene3D G3DSA:3.20.10.10 115 281 1.5E-53 T 12-10-2018 UA74_29160 8836d68ce467b6dc033614a00b0b60dd 283 Pfam PF01063 Amino-transferase class IV 31 254 6.9E-44 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 UA74_26035 58427b850eaa144d994c66619d44cdea 463 Gene3D G3DSA:3.40.50.300 1 201 1.4E-10 T 12-10-2018 UA74_26035 58427b850eaa144d994c66619d44cdea 463 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 205 393 2.0E-18 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_26035 58427b850eaa144d994c66619d44cdea 463 SUPERFAMILY SSF52540 2 399 1.87E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26035 58427b850eaa144d994c66619d44cdea 463 Gene3D G3DSA:3.40.50.300 223 414 2.0E-5 T 12-10-2018 UA74_26035 58427b850eaa144d994c66619d44cdea 463 Pfam PF11398 Protein of unknown function (DUF2813) 2 44 6.2E-5 T 12-10-2018 IPR022602 Protein of unknown function DUF2813 UA74_26830 af87f852430a1d442cefac6edc1bc134 105 Gene3D G3DSA:1.10.287.1060 1 97 3.8E-11 T 12-10-2018 UA74_26830 af87f852430a1d442cefac6edc1bc134 105 SUPERFAMILY SSF140453 1 98 6.02E-12 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_26830 af87f852430a1d442cefac6edc1bc134 105 Pfam PF06013 Proteins of 100 residues with WXG 2 91 2.4E-6 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like UA74_24505 232b123868f44c59d6a6f66064b783a8 251 Gene3D G3DSA:2.40.240.20 10 78 5.5E-20 T 12-10-2018 UA74_24505 232b123868f44c59d6a6f66064b783a8 251 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 13 249 1.5E-41 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 UA74_24505 232b123868f44c59d6a6f66064b783a8 251 PIRSF PIRSF015601 12 251 3.8E-51 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 UA74_24505 232b123868f44c59d6a6f66064b783a8 251 SUPERFAMILY SSF75217 82 251 9.94E-43 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_24505 232b123868f44c59d6a6f66064b783a8 251 Gene3D G3DSA:3.40.1280.10 80 251 3.1E-54 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_24505 232b123868f44c59d6a6f66064b783a8 251 SUPERFAMILY SSF88697 16 77 4.97E-12 T 12-10-2018 IPR015947 PUA-like superfamily UA74_24505 232b123868f44c59d6a6f66064b783a8 251 Pfam PF04452 RNA methyltransferase 26 245 5.3E-60 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Gene3D G3DSA:3.30.9.10 112 177 1.0E-11 T 12-10-2018 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 487 7.0E-189 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 6 489 1.1E-185 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Pfam PF01565 FAD binding domain 572 709 5.3E-37 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Gene3D G3DSA:3.30.465.10 627 748 4.9E-47 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 SUPERFAMILY SSF55103 752 1001 4.25E-55 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 SUPERFAMILY SSF56176 535 747 1.46E-75 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 3 489 44.345 T 12-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Gene3D G3DSA:3.30.70.2190 750 872 1.1E-34 T 12-10-2018 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Gene3D G3DSA:3.30.43.10 525 625 1.6E-26 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Gene3D G3DSA:3.30.70.2740 873 959 4.8E-28 T 12-10-2018 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Pfam PF02913 FAD linked oxidases, C-terminal domain 751 999 3.1E-49 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Gene3D G3DSA:1.10.45.10 960 1000 4.0E-17 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 Gene3D G3DSA:3.50.50.60 9 254 1.0E-11 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_05540 e48a9f9d61628b0c13e6b5c2c94664e8 1003 SUPERFAMILY SSF51905 5 272 5.18E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 Pfam PF00571 CBS domain 326 391 1.5E-4 T 12-10-2018 IPR000644 CBS domain UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 Pfam PF00571 CBS domain 402 454 1.5E-6 T 12-10-2018 IPR000644 CBS domain UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 SUPERFAMILY SSF53686 1 317 9.95E-95 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 454 3.2E-197 T 12-10-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 Gene3D G3DSA:3.40.50.1100 9 304 1.0E-116 T 12-10-2018 UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 Gene3D G3DSA:3.40.50.1100 41 154 1.0E-116 T 12-10-2018 UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 SMART SM00116 409 454 3.6E-4 T 12-10-2018 IPR000644 CBS domain UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 SMART SM00116 339 392 0.05 T 12-10-2018 IPR000644 CBS domain UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 Gene3D G3DSA:3.10.580.10 319 456 4.5E-18 T 12-10-2018 UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 SUPERFAMILY SSF54631 325 455 3.28E-17 T 12-10-2018 UA74_03850 8883c1a076b6f2a60f578b3b1a8f55be 457 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 296 2.4E-64 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_12420 646a3c195c85933b1a95e8254f720e42 698 Gene3D G3DSA:3.40.50.970 2 354 1.9E-117 T 12-10-2018 UA74_12420 646a3c195c85933b1a95e8254f720e42 698 Gene3D G3DSA:3.40.50.970 356 566 2.1E-85 T 12-10-2018 UA74_12420 646a3c195c85933b1a95e8254f720e42 698 ProSitePatterns PS00802 Transketolase signature 2. 497 513 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_12420 646a3c195c85933b1a95e8254f720e42 698 Pfam PF02780 Transketolase, C-terminal domain 577 684 3.6E-11 T 12-10-2018 IPR033248 Transketolase, C-terminal domain UA74_12420 646a3c195c85933b1a95e8254f720e42 698 SUPERFAMILY SSF52922 560 694 1.7E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_12420 646a3c195c85933b1a95e8254f720e42 698 SMART SM00861 375 555 6.7E-74 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_12420 646a3c195c85933b1a95e8254f720e42 698 SUPERFAMILY SSF52518 366 556 5.58E-69 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_12420 646a3c195c85933b1a95e8254f720e42 698 TIGRFAM TIGR00232 tktlase_bact: transketolase 25 690 6.2E-242 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 UA74_12420 646a3c195c85933b1a95e8254f720e42 698 SUPERFAMILY SSF52518 17 344 6.12E-103 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_12420 646a3c195c85933b1a95e8254f720e42 698 ProSitePatterns PS00801 Transketolase signature 1. 31 51 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_12420 646a3c195c85933b1a95e8254f720e42 698 Pfam PF02779 Transketolase, pyrimidine binding domain 374 554 8.5E-50 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_12420 646a3c195c85933b1a95e8254f720e42 698 Gene3D G3DSA:3.40.50.920 567 693 5.1E-39 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_12420 646a3c195c85933b1a95e8254f720e42 698 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 23 358 2.0E-138 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_15380 540c2f4acc9d76e4f84f6a6093b9456c 198 SUPERFAMILY SSF46689 13 93 3.64E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_15380 540c2f4acc9d76e4f84f6a6093b9456c 198 Gene3D G3DSA:1.10.357.10 8 198 1.2E-47 T 12-10-2018 UA74_15380 540c2f4acc9d76e4f84f6a6093b9456c 198 SUPERFAMILY SSF48498 92 195 9.85E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_15380 540c2f4acc9d76e4f84f6a6093b9456c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 5.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15380 540c2f4acc9d76e4f84f6a6093b9456c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 5.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15380 540c2f4acc9d76e4f84f6a6093b9456c 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 4.6E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_12145 5e915fe8076cbb7645885e7d59bdaead 144 Pfam PF01220 Dehydroquinase class II 3 138 2.0E-53 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_12145 5e915fe8076cbb7645885e7d59bdaead 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 141 1.6E-56 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_12145 5e915fe8076cbb7645885e7d59bdaead 144 SUPERFAMILY SSF52304 2 142 4.45E-55 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_12145 5e915fe8076cbb7645885e7d59bdaead 144 Gene3D G3DSA:3.40.50.9100 1 144 4.5E-58 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_12145 5e915fe8076cbb7645885e7d59bdaead 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 61.39 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_12145 5e915fe8076cbb7645885e7d59bdaead 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 18 140 2.0E-41 T 12-10-2018 UA74_12145 5e915fe8076cbb7645885e7d59bdaead 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 6 23 - T 12-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_12145 5e915fe8076cbb7645885e7d59bdaead 144 PIRSF PIRSF001399 1 144 3.3E-56 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 Pfam PF01225 Mur ligase family, catalytic domain 40 114 7.7E-9 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 Gene3D G3DSA:3.40.1390.10 11 119 9.6E-30 T 12-10-2018 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 SUPERFAMILY SSF53623 120 345 4.06E-62 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 SUPERFAMILY SSF53244 347 505 1.44E-43 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 SUPERFAMILY SSF63418 34 118 9.42E-17 T 12-10-2018 IPR035911 MurE/MurF, N-terminal UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 Gene3D G3DSA:3.90.190.20 349 509 5.9E-52 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 Pfam PF08245 Mur ligase middle domain 129 327 5.6E-37 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 38 504 7.2E-136 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 Gene3D G3DSA:3.40.1190.10 120 348 3.4E-77 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 Pfam PF02875 Mur ligase family, glutamate ligase domain 347 431 6.6E-19 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UA74_09620 e998ebf2556389c0be0537a5fc4e2f0f 513 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 15 504 31.278 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UA74_10245 b704a4a6219bbaec94d60c9e01ae77ea 538 SUPERFAMILY SSF56112 11 307 3.2E-63 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_10245 b704a4a6219bbaec94d60c9e01ae77ea 538 SMART SM00220 18 306 5.9E-49 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_10245 b704a4a6219bbaec94d60c9e01ae77ea 538 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 47 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_10245 b704a4a6219bbaec94d60c9e01ae77ea 538 Gene3D G3DSA:1.10.510.10 121 316 3.8E-43 T 12-10-2018 UA74_10245 b704a4a6219bbaec94d60c9e01ae77ea 538 Gene3D G3DSA:1.25.40.10 329 518 1.2E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_10245 b704a4a6219bbaec94d60c9e01ae77ea 538 Gene3D G3DSA:3.30.200.20 7 119 4.4E-25 T 12-10-2018 UA74_10245 b704a4a6219bbaec94d60c9e01ae77ea 538 SUPERFAMILY SSF48452 358 492 3.8E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_10245 b704a4a6219bbaec94d60c9e01ae77ea 538 Pfam PF00069 Protein kinase domain 18 299 3.1E-40 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_10245 b704a4a6219bbaec94d60c9e01ae77ea 538 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 163 175 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_23895 0751d495f6033a95a8f5b675b58023e1 107 Gene3D G3DSA:3.30.1310.10 3 104 1.4E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_23895 0751d495f6033a95a8f5b675b58023e1 107 Pfam PF02575 YbaB/EbfC DNA-binding family 18 100 6.5E-10 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_23895 0751d495f6033a95a8f5b675b58023e1 107 SUPERFAMILY SSF82607 19 101 2.09E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_04990 24425d5bd6a882373bff363916d08f43 457 ProSitePatterns PS00216 Sugar transport proteins signature 1. 285 301 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_04990 24425d5bd6a882373bff363916d08f43 457 Pfam PF07690 Major Facilitator Superfamily 33 263 4.7E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_04990 24425d5bd6a882373bff363916d08f43 457 Gene3D G3DSA:1.20.1250.20 26 258 2.1E-43 T 12-10-2018 UA74_04990 24425d5bd6a882373bff363916d08f43 457 PRINTS PR01035 Tetracycline resistance protein signature 153 175 1.2E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_04990 24425d5bd6a882373bff363916d08f43 457 PRINTS PR01035 Tetracycline resistance protein signature 181 201 1.2E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_04990 24425d5bd6a882373bff363916d08f43 457 PRINTS PR01035 Tetracycline resistance protein signature 267 287 1.2E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_04990 24425d5bd6a882373bff363916d08f43 457 PRINTS PR01035 Tetracycline resistance protein signature 38 54 1.2E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_04990 24425d5bd6a882373bff363916d08f43 457 Pfam PF00083 Sugar (and other) transporter 265 408 3.8E-7 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UA74_04990 24425d5bd6a882373bff363916d08f43 457 SUPERFAMILY SSF103473 14 415 7.72E-77 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_04990 24425d5bd6a882373bff363916d08f43 457 Gene3D G3DSA:1.20.1720.10 259 429 1.4E-25 T 12-10-2018 UA74_10950 d992870af58d104e761df53fb1e41a78 284 Gene3D G3DSA:3.90.25.10 135 265 3.8E-73 T 12-10-2018 UA74_10950 d992870af58d104e761df53fb1e41a78 284 SUPERFAMILY SSF51735 5 252 8.45E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_10950 d992870af58d104e761df53fb1e41a78 284 Pfam PF05368 NmrA-like family 6 217 9.2E-25 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 UA74_10950 d992870af58d104e761df53fb1e41a78 284 Gene3D G3DSA:3.40.50.720 7 263 3.8E-73 T 12-10-2018 UA74_03025 13160b260407aa8d12796cb0c71cf058 136 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 25 136 1.8E-40 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_03025 13160b260407aa8d12796cb0c71cf058 136 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 22 136 28.079 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_03025 13160b260407aa8d12796cb0c71cf058 136 SUPERFAMILY SSF53137 23 134 5.01E-48 T 12-10-2018 UA74_03025 13160b260407aa8d12796cb0c71cf058 136 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 23 136 6.1E-48 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03025 13160b260407aa8d12796cb0c71cf058 136 Gene3D G3DSA:3.30.420.100 22 136 1.9E-40 T 12-10-2018 UA74_27945 7581c5cd6be9a4aa6d12efb24188e61a 184 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 12 155 1.3E-32 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 UA74_27945 7581c5cd6be9a4aa6d12efb24188e61a 184 Pfam PF00583 Acetyltransferase (GNAT) family 37 135 3.9E-17 T 12-10-2018 IPR000182 GNAT domain UA74_27945 7581c5cd6be9a4aa6d12efb24188e61a 184 Gene3D G3DSA:3.40.630.30 5 169 1.0E-37 T 12-10-2018 UA74_27945 7581c5cd6be9a4aa6d12efb24188e61a 184 SUPERFAMILY SSF55729 1 157 4.18E-29 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_20490 70a4106e1aa53f7fee02172287eb9784 488 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 279 475 3.5E-55 T 12-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal UA74_20490 70a4106e1aa53f7fee02172287eb9784 488 Gene3D G3DSA:2.40.110.10 146 271 4.4E-37 T 12-10-2018 UA74_20490 70a4106e1aa53f7fee02172287eb9784 488 SUPERFAMILY SSF56645 1 271 1.49E-72 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_20490 70a4106e1aa53f7fee02172287eb9784 488 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 269 1.6E-83 T 12-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal UA74_20490 70a4106e1aa53f7fee02172287eb9784 488 Gene3D G3DSA:1.20.140.10 274 483 2.1E-49 T 12-10-2018 UA74_20490 70a4106e1aa53f7fee02172287eb9784 488 SUPERFAMILY SSF47203 261 476 4.38E-63 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_20490 70a4106e1aa53f7fee02172287eb9784 488 Gene3D G3DSA:1.10.3140.10 2 142 2.6E-31 T 12-10-2018 UA74_20490 70a4106e1aa53f7fee02172287eb9784 488 PIRSF PIRSF000331 1 482 6.5E-100 T 12-10-2018 IPR004925 HpaB/PvcC/4-BUDH UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.2E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 Gene3D G3DSA:1.10.10.10 2 70 1.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 Gene3D G3DSA:1.20.120.530 88 225 7.1E-32 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 SUPERFAMILY SSF48008 88 220 1.28E-29 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 SMART SM00345 7 66 4.0E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 SUPERFAMILY SSF46785 2 70 2.4E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 SMART SM00895 92 214 8.3E-22 T 12-10-2018 IPR011711 GntR, C-terminal UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 7.8E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 7.8E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_11850 3b59616c16313705a14ea74f2d1b5045 230 Pfam PF07729 FCD domain 92 213 1.7E-29 T 12-10-2018 IPR011711 GntR, C-terminal UA74_19535 a66199816be4c1bcd6202531202dce90 225 Pfam PF01081 KDPG and KHG aldolase 16 207 8.4E-43 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_19535 a66199816be4c1bcd6202531202dce90 225 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 135 148 - T 12-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_19535 a66199816be4c1bcd6202531202dce90 225 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 16 214 6.7E-52 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_19535 a66199816be4c1bcd6202531202dce90 225 Gene3D G3DSA:3.20.20.70 13 220 6.2E-70 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_19535 a66199816be4c1bcd6202531202dce90 225 SUPERFAMILY SSF51569 14 215 6.41E-58 T 12-10-2018 UA74_21050 cb591f07909023aba3ea362afd942ca7 436 Gene3D G3DSA:3.40.50.1970 41 217 2.7E-50 T 12-10-2018 UA74_21050 cb591f07909023aba3ea362afd942ca7 436 SUPERFAMILY SSF56796 54 405 1.83E-75 T 12-10-2018 UA74_21050 cb591f07909023aba3ea362afd942ca7 436 Pfam PF01761 3-dehydroquinate synthase 112 370 9.5E-62 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_21050 cb591f07909023aba3ea362afd942ca7 436 Gene3D G3DSA:1.20.1090.10 218 412 1.2E-60 T 12-10-2018 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 Gene3D G3DSA:3.30.930.10 1 296 1.1E-99 T 12-10-2018 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 Pfam PF03129 Anticodon binding domain 305 392 2.2E-9 T 12-10-2018 IPR004154 Anticodon-binding UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 SUPERFAMILY SSF52954 293 406 1.34E-18 T 12-10-2018 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 86 291 3.6E-25 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 124 147 5.0E-43 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 228 256 5.0E-43 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 271 284 5.0E-43 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 298 310 5.0E-43 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 PRINTS PR01047 Threonyl-tRNA synthetase signature 91 119 5.0E-43 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 2 393 2.0E-131 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 Gene3D G3DSA:3.40.50.800 297 407 2.8E-18 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily UA74_19565 02ef8dde54e6f4b59a8faea159a07d60 409 SUPERFAMILY SSF55681 3 290 8.48E-84 T 12-10-2018 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Pfam PF00698 Acyl transferase domain 617 805 2.3E-14 T 12-10-2018 IPR014043 Acyl transferase UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 580 819 2.6E-10 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Gene3D G3DSA:3.10.129.110 1088 1336 3.9E-14 T 12-10-2018 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 SUPERFAMILY SSF53901 5 465 6.77E-75 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 SUPERFAMILY SSF56214 1474 1555 3.31E-13 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 SUPERFAMILY SSF52151 577 830 2.25E-23 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 1474 1558 3.4E-10 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 SUPERFAMILY SSF55048 670 726 1.11E-5 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Gene3D G3DSA:3.90.470.20 1475 1572 1.3E-12 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Gene3D G3DSA:3.40.366.10 593 812 5.4E-37 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 SMART SM00825 Beta-ketoacyl synthase 8 469 3.9E-96 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 204 220 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 7 291 1.3E-56 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 424 476 5.0E-8 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Gene3D G3DSA:3.30.70.250 661 728 5.4E-37 T 12-10-2018 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Gene3D G3DSA:3.90.470.20 1366 1469 8.6E-10 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Pfam PF14765 Polyketide synthase dehydratase 1087 1338 2.8E-12 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 SUPERFAMILY SSF56214 1380 1465 5.62E-10 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_21845 7780fae262f5ffd1d372fee7bb8fd77e 1635 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 299 417 6.2E-33 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_09645 798c90b04787cb54f814f992fa0d8475 402 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 47 400 30.189 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_09645 798c90b04787cb54f814f992fa0d8475 402 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 46 395 2.9E-82 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_09645 798c90b04787cb54f814f992fa0d8475 402 Gene3D G3DSA:3.40.50.2000 203 384 1.5E-91 T 12-10-2018 UA74_09645 798c90b04787cb54f814f992fa0d8475 402 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 47 185 3.6E-37 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_09645 798c90b04787cb54f814f992fa0d8475 402 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 231 391 2.7E-34 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 UA74_09645 798c90b04787cb54f814f992fa0d8475 402 Gene3D G3DSA:3.40.50.2000 48 390 1.5E-91 T 12-10-2018 UA74_09645 798c90b04787cb54f814f992fa0d8475 402 SUPERFAMILY SSF53756 47 400 9.65E-94 T 12-10-2018 UA74_11240 9f0d2bec823bb8fc9f19183fcd513d68 268 SUPERFAMILY SSF50494 42 266 1.28E-66 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_11240 9f0d2bec823bb8fc9f19183fcd513d68 268 Pfam PF00089 Trypsin 44 259 1.8E-54 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_11240 9f0d2bec823bb8fc9f19183fcd513d68 268 Gene3D G3DSA:2.40.10.10 44 256 1.9E-71 T 12-10-2018 UA74_11240 9f0d2bec823bb8fc9f19183fcd513d68 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 216 228 4.6E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_11240 9f0d2bec823bb8fc9f19183fcd513d68 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 71 86 4.6E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_11240 9f0d2bec823bb8fc9f19183fcd513d68 268 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 127 141 4.6E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_11240 9f0d2bec823bb8fc9f19183fcd513d68 268 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 217 228 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site UA74_11240 9f0d2bec823bb8fc9f19183fcd513d68 268 SMART SM00020 43 262 4.7E-69 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_11240 9f0d2bec823bb8fc9f19183fcd513d68 268 Gene3D G3DSA:2.40.10.10 56 258 1.9E-71 T 12-10-2018 UA74_22320 edfabe5f6eff627e38c23f9987ab7c36 267 Gene3D G3DSA:3.30.450.40 88 266 3.8E-35 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_22320 edfabe5f6eff627e38c23f9987ab7c36 267 Pfam PF09339 IclR helix-turn-helix domain 17 65 7.6E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_22320 edfabe5f6eff627e38c23f9987ab7c36 267 Gene3D G3DSA:1.10.10.10 13 87 3.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22320 edfabe5f6eff627e38c23f9987ab7c36 267 SUPERFAMILY SSF55781 88 261 3.01E-33 T 12-10-2018 UA74_22320 edfabe5f6eff627e38c23f9987ab7c36 267 SUPERFAMILY SSF46785 15 88 3.5E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22320 edfabe5f6eff627e38c23f9987ab7c36 267 SMART SM00346 15 105 1.1E-21 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_22320 edfabe5f6eff627e38c23f9987ab7c36 267 Pfam PF01614 Bacterial transcriptional regulator 137 258 6.2E-15 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_15810 13f3d45efcf7cb1af8bab1ce6876e12e 340 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 8 243 7.5E-24 T 12-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR UA74_15810 13f3d45efcf7cb1af8bab1ce6876e12e 340 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 13 308 1.7E-50 T 12-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap UA74_24460 3cc4832157a70fd477100a37e589f78a 257 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 26.263 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 UA74_24460 3cc4832157a70fd477100a37e589f78a 257 Pfam PF11967 Recombination protein O N terminal 1 79 1.3E-25 T 12-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal UA74_24460 3cc4832157a70fd477100a37e589f78a 257 Pfam PF02565 Recombination protein O C terminal 85 238 4.6E-36 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 UA74_24460 3cc4832157a70fd477100a37e589f78a 257 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 206 1.6E-31 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 UA74_24460 3cc4832157a70fd477100a37e589f78a 257 SUPERFAMILY SSF57863 83 232 1.2E-39 T 12-10-2018 IPR037278 ARFGAP/RecO-like zinc finger UA74_24460 3cc4832157a70fd477100a37e589f78a 257 Gene3D G3DSA:2.40.50.140 2 81 1.9E-27 T 12-10-2018 UA74_24460 3cc4832157a70fd477100a37e589f78a 257 SUPERFAMILY SSF50249 1 79 1.88E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_10155 ae0ce6709c7d9130832b369720cd6b0b 433 SUPERFAMILY SSF53474 125 375 2.1E-6 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_10155 ae0ce6709c7d9130832b369720cd6b0b 433 Pfam PF06259 Alpha/beta hydrolase 273 366 7.9E-25 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 UA74_10155 ae0ce6709c7d9130832b369720cd6b0b 433 Pfam PF06259 Alpha/beta hydrolase 147 253 4.6E-21 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 SUPERFAMILY SSF52540 1036 1246 1.56E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 SUPERFAMILY SSF90123 722 1006 2.09E-24 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 721 1222 2.2E-124 T 12-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 SUPERFAMILY SSF52540 489 692 2.26E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 SUPERFAMILY SSF90123 46 371 4.84E-34 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 Pfam PF00005 ABC transporter 510 658 3.1E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 Pfam PF00664 ABC transporter transmembrane region 181 335 9.3E-9 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 SMART SM00382 1068 1239 1.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 SMART SM00382 523 730 2.3E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 Gene3D G3DSA:3.40.50.300 1028 1259 1.1E-56 T 12-10-2018 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 Gene3D G3DSA:3.40.50.300 486 703 1.6E-42 T 12-10-2018 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 Gene3D G3DSA:1.20.1560.10 704 1015 1.0E-14 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 Gene3D G3DSA:1.20.1560.10 39 375 3.2E-32 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_00560 7ed5dc6cc1ff27b12b4bce4eaf23fec5 1277 Pfam PF00005 ABC transporter 1059 1193 1.2E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_25160 c211cf3fb6d7db5fbd7564905d01290b 529 SUPERFAMILY SSF53474 118 512 7.46E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_25160 c211cf3fb6d7db5fbd7564905d01290b 529 Pfam PF00561 alpha/beta hydrolase fold 118 505 7.6E-47 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_14105 6fe1bd750fc8951e946f97ccad48b225 416 Gene3D G3DSA:3.30.590.20 31 394 5.2E-108 T 12-10-2018 UA74_14105 6fe1bd750fc8951e946f97ccad48b225 416 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 416 71.186 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_14105 6fe1bd750fc8951e946f97ccad48b225 416 SUPERFAMILY SSF55931 33 391 1.47E-84 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UA74_14105 6fe1bd750fc8951e946f97ccad48b225 416 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 37 318 3.0E-77 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_14105 6fe1bd750fc8951e946f97ccad48b225 416 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 38 315 2.3E-47 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 SUPERFAMILY SSF51905 5 311 8.98E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 Gene3D G3DSA:3.50.50.60 7 303 1.8E-96 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 Gene3D G3DSA:3.30.390.30 322 404 6.4E-13 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 3.5E-21 T 12-10-2018 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 3.5E-21 T 12-10-2018 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.5E-21 T 12-10-2018 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 3.5E-21 T 12-10-2018 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.5E-21 T 12-10-2018 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 SUPERFAMILY SSF55424 315 391 2.2E-19 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 Gene3D G3DSA:3.50.50.60 116 241 1.8E-96 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 3.9E-17 T 12-10-2018 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 3.9E-17 T 12-10-2018 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.9E-17 T 12-10-2018 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 3.9E-17 T 12-10-2018 UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 Pfam PF14759 Reductase C-terminal 322 389 9.5E-13 T 12-10-2018 IPR028202 Reductase, C-terminal UA74_17395 4b2af2fe66d86c8438d103817b79992a 419 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 303 1.7E-45 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 2.3E-28 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 SUPERFAMILY SSF56645 2 240 5.76E-84 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 SUPERFAMILY SSF47203 226 378 1.18E-55 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 Gene3D G3DSA:2.40.110.10 121 235 1.3E-38 T 12-10-2018 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 Gene3D G3DSA:1.20.140.10 236 383 4.2E-56 T 12-10-2018 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 8.2E-36 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 Gene3D G3DSA:1.10.540.10 1 120 3.1E-40 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 PIRSF PIRSF016578 3 379 2.9E-20 T 12-10-2018 UA74_13555 fbaa355c131db894fcdb38b03a298fff 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 3.8E-52 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_11610 d29b54a419510b510f9bd5951bbf6000 469 SUPERFAMILY SSF75304 5 465 1.83E-133 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_11610 d29b54a419510b510f9bd5951bbf6000 469 Gene3D G3DSA:3.90.1300.10 2 468 6.1E-149 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_11610 d29b54a419510b510f9bd5951bbf6000 469 Pfam PF01425 Amidase 27 447 1.2E-104 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_11610 d29b54a419510b510f9bd5951bbf6000 469 ProSitePatterns PS00571 Amidases signature. 155 186 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 UA74_21385 0e9956e5068230234653def4dfd7dd85 307 Gene3D G3DSA:1.10.10.10 1 93 5.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21385 0e9956e5068230234653def4dfd7dd85 307 Gene3D G3DSA:3.40.190.10 94 279 1.6E-39 T 12-10-2018 UA74_21385 0e9956e5068230234653def4dfd7dd85 307 Pfam PF03466 LysR substrate binding domain 89 291 1.6E-34 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_21385 0e9956e5068230234653def4dfd7dd85 307 Gene3D G3DSA:3.40.190.10 170 269 1.6E-39 T 12-10-2018 UA74_21385 0e9956e5068230234653def4dfd7dd85 307 SUPERFAMILY SSF46785 2 112 2.18E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_21385 0e9956e5068230234653def4dfd7dd85 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 7.4E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_21385 0e9956e5068230234653def4dfd7dd85 307 SUPERFAMILY SSF53850 90 298 9.59E-33 T 12-10-2018 UA74_04345 6c8c1a25fdd902e75373aaee8b1d897c 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 123 196 1.6E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_04345 6c8c1a25fdd902e75373aaee8b1d897c 218 SMART SM00862 122 197 1.1E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_04345 6c8c1a25fdd902e75373aaee8b1d897c 218 SMART SM00448 1 88 1.2E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_04345 6c8c1a25fdd902e75373aaee8b1d897c 218 SUPERFAMILY SSF52172 2 156 3.98E-28 T 12-10-2018 IPR011006 CheY-like superfamily UA74_04345 6c8c1a25fdd902e75373aaee8b1d897c 218 Pfam PF00072 Response regulator receiver domain 2 87 5.3E-18 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_04345 6c8c1a25fdd902e75373aaee8b1d897c 218 Gene3D G3DSA:1.10.10.10 102 202 4.2E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04345 6c8c1a25fdd902e75373aaee8b1d897c 218 Gene3D G3DSA:3.40.50.2300 1 101 1.6E-24 T 12-10-2018 UA74_06905 182b8a147edf101fb02c6dd591f5e938 289 Gene3D G3DSA:3.10.310.10 129 284 2.9E-72 T 12-10-2018 UA74_06905 182b8a147edf101fb02c6dd591f5e938 289 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 12 287 1.7E-49 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_06905 182b8a147edf101fb02c6dd591f5e938 289 PIRSF PIRSF016184 9 289 1.7E-58 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_06905 182b8a147edf101fb02c6dd591f5e938 289 Pfam PF02567 Phenazine biosynthesis-like protein 19 287 2.7E-70 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_06905 182b8a147edf101fb02c6dd591f5e938 289 Gene3D G3DSA:3.10.310.10 19 285 2.9E-72 T 12-10-2018 UA74_06905 182b8a147edf101fb02c6dd591f5e938 289 SUPERFAMILY SSF54506 10 287 1.45E-60 T 12-10-2018 UA74_14150 92419037363b19747eefa4d43bdc1d0a 201 Gene3D G3DSA:3.30.2170.10 1 201 3.8E-72 T 12-10-2018 UA74_14150 92419037363b19747eefa4d43bdc1d0a 201 Hamap MF_00801 Endonuclease V [nfi]. 4 201 26.855 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 UA74_14150 92419037363b19747eefa4d43bdc1d0a 201 Pfam PF04493 Endonuclease V 6 196 3.0E-64 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 UA74_22650 92b7513ce0f28f14eb5115b059ae23f7 309 Gene3D G3DSA:1.10.3720.10 85 299 3.1E-21 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22650 92b7513ce0f28f14eb5115b059ae23f7 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 305 4.5E-37 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_22650 92b7513ce0f28f14eb5115b059ae23f7 309 SUPERFAMILY SSF161098 88 290 4.58E-15 T 12-10-2018 IPR035906 MetI-like superfamily UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SUPERFAMILY SSF48452 97 265 2.53E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Pfam PF13374 Tetratricopeptide repeat 720 752 4.5E-4 T 12-10-2018 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Pfam PF13424 Tetratricopeptide repeat 762 830 2.4E-9 T 12-10-2018 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Gene3D G3DSA:3.40.50.300 264 422 1.5E-27 T 12-10-2018 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SMART SM01043 102 244 2.2E-38 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Gene3D G3DSA:1.25.40.10 101 263 1.5E-42 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Pfam PF13176 Tetratricopeptide repeat 842 866 0.032 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SMART SM00028 720 753 17.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SMART SM00028 760 793 69.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SMART SM00028 840 873 5.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SMART SM00028 880 913 59.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SMART SM00028 800 833 33.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Pfam PF00931 NB-ARC domain 293 538 3.7E-12 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SUPERFAMILY SSF46894 6 95 1.53E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SUPERFAMILY SSF48452 714 920 1.33E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 PRINTS PR00364 Disease resistance protein signature 376 390 2.3E-8 T 12-10-2018 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 PRINTS PR00364 Disease resistance protein signature 297 312 2.3E-8 T 12-10-2018 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 PRINTS PR00364 Disease resistance protein signature 464 478 2.3E-8 T 12-10-2018 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Gene3D G3DSA:1.10.10.10 1 98 4.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SUPERFAMILY SSF52540 264 534 3.04E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 94 2.3E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Gene3D G3DSA:1.25.40.10 660 925 4.2E-50 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 Pfam PF03704 Bacterial transcriptional activator domain 102 244 2.0E-33 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_13895 c0a86d2b7ec608a17c196f3325eaa009 928 SMART SM00862 19 95 1.3E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_08910 65e488b0c43be929fee0c6004b9a7258 504 SMART SM00382 211 393 4.2E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_08910 65e488b0c43be929fee0c6004b9a7258 504 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 1.1E-33 T 12-10-2018 UA74_08910 65e488b0c43be929fee0c6004b9a7258 504 SUPERFAMILY SSF52540 188 498 2.3E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08910 65e488b0c43be929fee0c6004b9a7258 504 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 499 1.5E-129 T 12-10-2018 IPR004482 Mg chelatase-related protein UA74_08910 65e488b0c43be929fee0c6004b9a7258 504 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 404 499 4.5E-22 T 12-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain UA74_08910 65e488b0c43be929fee0c6004b9a7258 504 Gene3D G3DSA:3.30.230.10 1 169 2.6E-8 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_08910 65e488b0c43be929fee0c6004b9a7258 504 SUPERFAMILY SSF54211 2 170 4.17E-29 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_08910 65e488b0c43be929fee0c6004b9a7258 504 Gene3D G3DSA:3.40.50.300 187 390 5.1E-40 T 12-10-2018 UA74_08910 65e488b0c43be929fee0c6004b9a7258 504 Pfam PF01078 Magnesium chelatase, subunit ChlI 191 393 5.9E-79 T 12-10-2018 IPR000523 Magnesium chelatase ChlI domain UA74_21180 487a7c8fda05c9b235a0eddd382b9ede 416 SUPERFAMILY SSF53756 19 412 1.53E-68 T 12-10-2018 UA74_21180 487a7c8fda05c9b235a0eddd382b9ede 416 Pfam PF13439 Glycosyltransferase Family 4 32 219 2.6E-19 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_21180 487a7c8fda05c9b235a0eddd382b9ede 416 Gene3D G3DSA:3.40.50.2000 23 411 8.4E-61 T 12-10-2018 UA74_21180 487a7c8fda05c9b235a0eddd382b9ede 416 Pfam PF00534 Glycosyl transferases group 1 228 394 1.3E-21 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_21180 487a7c8fda05c9b235a0eddd382b9ede 416 Gene3D G3DSA:3.40.50.2000 217 395 8.4E-61 T 12-10-2018 UA74_25630 30c8c7a28c614275bc0447839dbb6d78 178 SMART SM00347 45 148 1.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_25630 30c8c7a28c614275bc0447839dbb6d78 178 Gene3D G3DSA:1.10.10.10 3 163 6.3E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_25630 30c8c7a28c614275bc0447839dbb6d78 178 SUPERFAMILY SSF46785 15 162 6.69E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_25630 30c8c7a28c614275bc0447839dbb6d78 178 Pfam PF12802 MarR family 51 111 1.3E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Gene3D G3DSA:2.170.16.10 2889 3034 2.6E-41 T 12-10-2018 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 SUPERFAMILY SSF49899 1023 1200 1.58E-20 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF07591 Pretoxin HINT domain 2902 3035 5.5E-17 T 12-10-2018 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 1874 1908 1.5E-4 T 12-10-2018 IPR031325 RHS repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 1476 1506 2.8E-6 T 12-10-2018 IPR031325 RHS repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2254 2289 6.5E-6 T 12-10-2018 IPR031325 RHS repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2335 2373 2.6E-5 T 12-10-2018 IPR031325 RHS repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2406 2438 1.9E-5 T 12-10-2018 IPR031325 RHS repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2112 2145 4.1E-6 T 12-10-2018 IPR031325 RHS repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 2022 2058 1.2E-7 T 12-10-2018 IPR031325 RHS repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF05593 RHS Repeat 1926 1959 2.5E-6 T 12-10-2018 IPR031325 RHS repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Gene3D G3DSA:2.180.10.10 1396 1516 1.0E-5 T 12-10-2018 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Gene3D G3DSA:2.180.10.10 2286 2509 2.7E-6 T 12-10-2018 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Gene3D G3DSA:2.180.10.10 1605 1796 4.9E-10 T 12-10-2018 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Gene3D G3DSA:2.180.10.10 2005 2145 2.8E-12 T 12-10-2018 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Gene3D G3DSA:2.180.10.10 2551 2650 7.7E-11 T 12-10-2018 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2572 2651 1.1E-17 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1874 1900 1.9E-4 T 12-10-2018 IPR006530 YD repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1476 1507 2.5E-4 T 12-10-2018 IPR006530 YD repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2112 2143 1.3E-5 T 12-10-2018 IPR006530 YD repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1926 1959 1.3E-6 T 12-10-2018 IPR006530 YD repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2022 2060 1.8E-5 T 12-10-2018 IPR006530 YD repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2274 2311 5.6E-4 T 12-10-2018 IPR006530 YD repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2406 2436 5.6E-6 T 12-10-2018 IPR006530 YD repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2064 2098 5.4E-4 T 12-10-2018 IPR006530 YD repeat UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1029 1186 3.2E-15 T 12-10-2018 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 SUPERFAMILY SSF51294 2893 3033 9.29E-18 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 Gene3D G3DSA:2.60.120.200 1029 1209 8.9E-21 T 12-10-2018 UA74_05910 aecb34adc8cef397ff1c755905a93abf 3149 SMART SM00306 2890 2992 3.4E-12 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_05840 90d933742fb674263563f1ee82f6e0d7 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 64 2.8E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05840 90d933742fb674263563f1ee82f6e0d7 209 SUPERFAMILY SSF46689 12 84 2.0E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_05840 90d933742fb674263563f1ee82f6e0d7 209 Gene3D G3DSA:1.10.10.60 10 59 5.0E-21 T 12-10-2018 UA74_05840 90d933742fb674263563f1ee82f6e0d7 209 Gene3D G3DSA:1.10.357.10 61 203 7.3E-29 T 12-10-2018 UA74_07795 1c7485de980072183a81409dd2b38c38 569 SUPERFAMILY SSF53474 109 502 9.25E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07795 1c7485de980072183a81409dd2b38c38 569 Pfam PF00561 alpha/beta hydrolase fold 116 498 1.3E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19350 03b19123702f313aeded803ca08ea667 287 Gene3D G3DSA:3.60.15.10 71 283 2.2E-10 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_19350 03b19123702f313aeded803ca08ea667 287 SUPERFAMILY SSF56281 69 253 1.45E-24 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_10625 a3896000775a43a362cdf6076684da4e 237 SMART SM00382 28 215 3.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_10625 a3896000775a43a362cdf6076684da4e 237 Gene3D G3DSA:3.40.50.300 1 237 2.5E-67 T 12-10-2018 UA74_10625 a3896000775a43a362cdf6076684da4e 237 PIRSF PIRSF039137 1 237 3.4E-110 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 UA74_10625 a3896000775a43a362cdf6076684da4e 237 SUPERFAMILY SSF52540 3 233 1.96E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10625 a3896000775a43a362cdf6076684da4e 237 Pfam PF00005 ABC transporter 19 164 4.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_10625 a3896000775a43a362cdf6076684da4e 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.1E-26 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Gene3D G3DSA:2.30.30.30 1 62 1.6E-27 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SUPERFAMILY SSF50249 65 126 1.29E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 2.4E-75 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SUPERFAMILY SSF50249 129 185 3.6E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 PIRSF PIRSF005901 1 186 7.1E-65 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SMART SM01185 67 121 1.8E-26 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Gene3D G3DSA:2.40.50.140 128 187 4.8E-24 T 12-10-2018 UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 119 3.5E-21 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 48.659 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 9.0E-24 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SMART SM00841 129 184 9.2E-30 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 SUPERFAMILY SSF50104 2 63 3.79E-20 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily UA74_12170 4f513dd7d8fca4ca3ef6be042f28a3e0 187 Gene3D G3DSA:2.40.50.140 64 127 6.3E-24 T 12-10-2018 UA74_15300 df3e462772f6b19fede872ddc13aa639 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.4E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15300 df3e462772f6b19fede872ddc13aa639 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.4E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15300 df3e462772f6b19fede872ddc13aa639 185 SUPERFAMILY SSF46689 3 69 1.08E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_15300 df3e462772f6b19fede872ddc13aa639 185 Gene3D G3DSA:1.10.357.10 1 182 3.7E-51 T 12-10-2018 UA74_15300 df3e462772f6b19fede872ddc13aa639 185 SUPERFAMILY SSF48498 82 177 6.0E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_15300 df3e462772f6b19fede872ddc13aa639 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 4.1E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 SMART SM00354 18 89 3.7E-21 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Gene3D G3DSA:3.40.50.2300 73 321 1.2E-70 T 12-10-2018 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Gene3D G3DSA:3.40.50.2300 176 305 1.2E-70 T 12-10-2018 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 SUPERFAMILY SSF53822 79 346 1.02E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Gene3D G3DSA:1.10.260.40 12 72 1.1E-18 T 12-10-2018 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Pfam PF13377 Periplasmic binding protein-like domain 184 343 1.6E-36 T 12-10-2018 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 SUPERFAMILY SSF47413 18 77 1.94E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 30 40 9.6E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 20 30 9.6E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 20 65 2.7E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_24120 88e9c0ac2bfa2d9bdc4af412f44a6e2e 350 ProSitePatterns PS00356 LacI-type HTH domain signature. 21 39 - T 12-10-2018 UA74_14530 8d04113649d9ce8b74e0ab6b4d83f499 205 Pfam PF03358 NADPH-dependent FMN reductase 13 134 1.6E-13 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_14530 8d04113649d9ce8b74e0ab6b4d83f499 205 Gene3D G3DSA:3.40.50.360 1 204 1.7E-63 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_14530 8d04113649d9ce8b74e0ab6b4d83f499 205 SUPERFAMILY SSF52218 6 199 5.11E-48 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_14530 8d04113649d9ce8b74e0ab6b4d83f499 205 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 5 198 2.4E-44 T 12-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 UA74_21950 26172246544bd669dc098d8bbd4b66e2 407 SUPERFAMILY SSF51905 7 377 8.07E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_21950 26172246544bd669dc098d8bbd4b66e2 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 2.6E-18 T 12-10-2018 UA74_21950 26172246544bd669dc098d8bbd4b66e2 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.6E-18 T 12-10-2018 UA74_21950 26172246544bd669dc098d8bbd4b66e2 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 2.6E-18 T 12-10-2018 UA74_21950 26172246544bd669dc098d8bbd4b66e2 407 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 2.6E-18 T 12-10-2018 UA74_21950 26172246544bd669dc098d8bbd4b66e2 407 Gene3D G3DSA:3.30.9.50 44 279 1.7E-70 T 12-10-2018 UA74_21950 26172246544bd669dc098d8bbd4b66e2 407 Gene3D G3DSA:3.50.50.60 11 346 1.7E-70 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_21950 26172246544bd669dc098d8bbd4b66e2 407 Pfam PF01494 FAD binding domain 7 327 2.0E-24 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 10 494 31.366 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 39 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 208 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 14 26 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 43 56 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 PRINTS PR00987 Glutamyl-tRNA synthetase signature 214 222 4.7E-22 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 11 327 2.3E-78 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 11 492 4.4E-126 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 SUPERFAMILY SSF52374 11 323 4.56E-97 T 12-10-2018 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 Gene3D G3DSA:3.90.800.10 80 199 1.9E-89 T 12-10-2018 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 SUPERFAMILY SSF48163 324 494 1.44E-36 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 Gene3D G3DSA:1.10.10.350 398 497 3.1E-28 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 Gene3D G3DSA:3.40.50.620 11 252 1.9E-89 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_25875 34a81c21289c83cfc12859a8033a4b60 498 Gene3D G3DSA:1.10.1160.10 256 339 5.2E-30 T 12-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 367 1.8E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 SMART SM00387 257 369 1.1E-39 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 SMART SM00388 146 212 2.2E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 SUPERFAMILY SSF55874 202 367 1.07E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 Gene3D G3DSA:3.30.565.10 219 372 7.8E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 347 9.9E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 308 9.9E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 322 9.9E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 9.9E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 SUPERFAMILY SSF47384 138 210 3.53E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 Pfam PF00512 His Kinase A (phospho-acceptor) domain 147 211 9.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_02235 57c399a8ab0fd27aaccb7f6c30f6965b 415 Gene3D G3DSA:1.10.287.130 139 211 1.4E-16 T 12-10-2018 UA74_03470 c775907cd2c57def589a36a1563f58df 66 Pfam PF04149 Domain of unknown function (DUF397) 11 61 2.0E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_06020 3905ef83f914d958fb398b96c1c3c460 350 SUPERFAMILY SSF49265 45 129 4.47E-5 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 UA74_06020 3905ef83f914d958fb398b96c1c3c460 350 Gene3D G3DSA:2.60.40.10 42 132 5.9E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_06020 3905ef83f914d958fb398b96c1c3c460 350 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 154 347 4.5E-16 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal UA74_06020 3905ef83f914d958fb398b96c1c3c460 350 SUPERFAMILY SSF81296 154 349 7.98E-20 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_06020 3905ef83f914d958fb398b96c1c3c460 350 Gene3D G3DSA:2.70.50.50 154 349 6.0E-24 T 12-10-2018 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 279 289 3.0E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 37 47 3.0E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 364 385 3.0E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 120 139 3.0E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 PRINTS PR00171 Sugar transporter signature 387 399 3.0E-27 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 SUPERFAMILY SSF103473 21 460 1.31E-84 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 ProSitePatterns PS00216 Sugar transport proteins signature 1. 83 100 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 25 459 2.3E-121 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 Gene3D G3DSA:1.20.1250.20 21 463 1.5E-131 T 12-10-2018 UA74_22855 5bbe89d92fe6246983f991b7823a79db 477 Pfam PF00083 Sugar (and other) transporter 31 462 2.1E-121 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UA74_04630 a7eb53adb3d6edaee5dbbec3a62b078a 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 274 5.7E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_04630 a7eb53adb3d6edaee5dbbec3a62b078a 281 SUPERFAMILY SSF161098 11 281 7.01E-74 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04630 a7eb53adb3d6edaee5dbbec3a62b078a 281 Gene3D G3DSA:1.10.3720.10 5 272 6.0E-67 T 12-10-2018 IPR035906 MetI-like superfamily UA74_00320 06c2929f0b2c2319daf7530c13fef3e7 1251 SUPERFAMILY SSF53756 517 783 1.15E-31 T 12-10-2018 UA74_00320 06c2929f0b2c2319daf7530c13fef3e7 1251 Pfam PF05050 Methyltransferase FkbM domain 1051 1215 6.4E-13 T 12-10-2018 IPR006342 Methyltransferase FkbM UA74_00320 06c2929f0b2c2319daf7530c13fef3e7 1251 SUPERFAMILY SSF53448 6 256 1.29E-13 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_00320 06c2929f0b2c2319daf7530c13fef3e7 1251 SUPERFAMILY SSF53335 1016 1218 8.59E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_00320 06c2929f0b2c2319daf7530c13fef3e7 1251 Gene3D G3DSA:3.40.50.150 1037 1216 3.1E-30 T 12-10-2018 UA74_00320 06c2929f0b2c2319daf7530c13fef3e7 1251 Pfam PF00534 Glycosyl transferases group 1 591 761 7.4E-13 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_00320 06c2929f0b2c2319daf7530c13fef3e7 1251 Gene3D G3DSA:3.40.50.2000 578 784 2.5E-34 T 12-10-2018 UA74_00320 06c2929f0b2c2319daf7530c13fef3e7 1251 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 1048 1190 6.7E-22 T 12-10-2018 IPR006342 Methyltransferase FkbM UA74_29730 1ae9ade0f939c91bb9050cc732831ed3 407 SUPERFAMILY SSF81345 63 398 2.35E-83 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_29730 1ae9ade0f939c91bb9050cc732831ed3 407 Pfam PF01032 FecCD transport family 79 398 3.9E-94 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_29730 1ae9ade0f939c91bb9050cc732831ed3 407 Gene3D G3DSA:1.10.3470.10 65 405 2.7E-107 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_01825 56391fe0739d91a4dc17b7dd3dc966f0 328 Pfam PF00248 Aldo/keto reductase family 28 326 8.1E-64 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_01825 56391fe0739d91a4dc17b7dd3dc966f0 328 Gene3D G3DSA:3.20.20.100 15 328 4.6E-110 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_01825 56391fe0739d91a4dc17b7dd3dc966f0 328 SUPERFAMILY SSF51430 13 326 4.58E-88 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_08210 c5810897faef62aac76e36761e3b0b92 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08210 c5810897faef62aac76e36761e3b0b92 85 Pfam PF01016 Ribosomal L27 protein 2 80 1.2E-36 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08210 c5810897faef62aac76e36761e3b0b92 85 SUPERFAMILY SSF110324 2 81 9.07E-32 T 12-10-2018 UA74_08210 c5810897faef62aac76e36761e3b0b92 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 5.0E-16 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08210 c5810897faef62aac76e36761e3b0b92 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 6.9E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08210 c5810897faef62aac76e36761e3b0b92 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.7E-36 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08210 c5810897faef62aac76e36761e3b0b92 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.7E-36 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08210 c5810897faef62aac76e36761e3b0b92 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.7E-36 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08210 c5810897faef62aac76e36761e3b0b92 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 28.097 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08210 c5810897faef62aac76e36761e3b0b92 85 Gene3D G3DSA:2.40.50.100 21 85 7.0E-28 T 12-10-2018 UA74_03310 f4a81e201dc4279f161e24fa15bf3f3d 283 Gene3D G3DSA:3.20.20.30 4 283 1.2E-39 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_03310 f4a81e201dc4279f161e24fa15bf3f3d 283 SUPERFAMILY SSF51679 1 282 6.92E-43 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_03310 f4a81e201dc4279f161e24fa15bf3f3d 283 Pfam PF00296 Luciferase-like monooxygenase 19 230 9.0E-27 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_15960 77f8afb93db23dde8e62de5351b558d4 310 Gene3D G3DSA:3.90.1200.10 155 309 2.6E-6 T 12-10-2018 UA74_15960 77f8afb93db23dde8e62de5351b558d4 310 Pfam PF01636 Phosphotransferase enzyme family 40 247 9.4E-11 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_15960 77f8afb93db23dde8e62de5351b558d4 310 SUPERFAMILY SSF56112 38 281 4.96E-19 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 4.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 4.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 4.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 4.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 4.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 4.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 4.7E-61 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 SMART SM01096 422 545 2.2E-58 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.40.50.1380 958 1097 3.0E-39 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Pfam PF02142 MGS-like domain 978 1064 5.2E-20 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 716 730 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF56059 680 955 1.56E-94 T 12-10-2018 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:1.10.1030.10 406 551 2.0E-36 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 SMART SM00851 977 1064 1.8E-29 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF52440 1 127 1.27E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 845 852 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF52335 964 1093 8.24E-35 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.30.470.20 672 957 1.7E-107 T 12-10-2018 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF56059 128 400 2.3E-101 T 12-10-2018 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF52440 559 681 7.05E-45 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1074 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1092 13.239 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 SUPERFAMILY SSF48108 396 548 4.71E-41 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1085 12.98 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.30.470.20 120 402 5.8E-118 T 12-10-2018 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 882 4.6E-36 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 7.6E-66 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.40.50.20 1 116 1.3E-48 T 12-10-2018 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Gene3D G3DSA:3.40.50.20 556 669 7.5E-47 T 12-10-2018 UA74_12210 8f49e842e1580b8697a8f5f026a1155f 1101 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 545 9.9E-36 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_11895 e462540ffcc8e230a60affce657b104a 199 SUPERFAMILY SSF52499 2 193 3.92E-39 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_11895 e462540ffcc8e230a60affce657b104a 199 Gene3D G3DSA:3.40.50.850 1 196 4.7E-43 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_11895 e462540ffcc8e230a60affce657b104a 199 Pfam PF00857 Isochorismatase family 4 145 2.3E-32 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 UA74_04530 e4cdfc91106e0e544003b4667f2de4eb 489 SUPERFAMILY SSF140459 29 183 4.97E-7 T 12-10-2018 UA74_10635 523bbe22a8409f152a25617650072ce1 901 Gene3D G3DSA:3.30.70.370 635 896 1.8E-100 T 12-10-2018 UA74_10635 523bbe22a8409f152a25617650072ce1 901 ProSitePatterns PS00447 DNA polymerase family A signature. 726 745 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 Gene3D G3DSA:1.20.1060.10 515 629 6.6E-30 T 12-10-2018 UA74_10635 523bbe22a8409f152a25617650072ce1 901 SMART SM00474 312 490 3.2E-12 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 UA74_10635 523bbe22a8409f152a25617650072ce1 901 Gene3D G3DSA:1.10.150.20 681 824 1.8E-100 T 12-10-2018 UA74_10635 523bbe22a8409f152a25617650072ce1 901 SUPERFAMILY SSF47807 181 294 1.79E-29 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily UA74_10635 523bbe22a8409f152a25617650072ce1 901 SUPERFAMILY SSF53098 317 489 8.5E-29 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_10635 523bbe22a8409f152a25617650072ce1 901 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 12 180 1.0E-53 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 UA74_10635 523bbe22a8409f152a25617650072ce1 901 Gene3D G3DSA:3.30.420.10 345 513 2.7E-31 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_10635 523bbe22a8409f152a25617650072ce1 901 Pfam PF01612 3'-5' exonuclease 351 449 2.4E-5 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 UA74_10635 523bbe22a8409f152a25617650072ce1 901 Gene3D G3DSA:3.40.50.1010 13 287 6.0E-94 T 12-10-2018 UA74_10635 523bbe22a8409f152a25617650072ce1 901 TIGRFAM TIGR00593 pola: DNA polymerase I 13 899 1.8E-301 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 182 275 5.8E-27 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 UA74_10635 523bbe22a8409f152a25617650072ce1 901 SMART SM00279 183 218 2.4E-16 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 UA74_10635 523bbe22a8409f152a25617650072ce1 901 Pfam PF00476 DNA polymerase family A 527 897 1.5E-140 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 SMART SM00482 657 864 1.3E-108 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 SUPERFAMILY SSF56672 498 898 1.01E-133 T 12-10-2018 UA74_10635 523bbe22a8409f152a25617650072ce1 901 Gene3D G3DSA:1.10.150.20 184 256 6.0E-94 T 12-10-2018 UA74_10635 523bbe22a8409f152a25617650072ce1 901 SMART SM00475 11 271 3.4E-137 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 UA74_10635 523bbe22a8409f152a25617650072ce1 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 817 833 1.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 649 664 1.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 726 751 1.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 702 715 1.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 847 860 1.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 785 796 1.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 672 695 1.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 763 774 1.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 PRINTS PR00868 DNA-polymerase family A (pol I) signature 626 648 1.1E-75 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_10635 523bbe22a8409f152a25617650072ce1 901 SUPERFAMILY SSF88723 9 180 1.84E-52 T 12-10-2018 IPR029060 PIN-like domain superfamily UA74_12760 e453602c3ce19c91315caeb33f42213e 269 Pfam PF13847 Methyltransferase domain 38 166 1.0E-23 T 12-10-2018 IPR025714 Methyltransferase domain UA74_12760 e453602c3ce19c91315caeb33f42213e 269 Gene3D G3DSA:3.40.50.150 3 257 4.9E-41 T 12-10-2018 UA74_12760 e453602c3ce19c91315caeb33f42213e 269 SUPERFAMILY SSF53335 8 256 1.42E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_18905 a7109eacd12cbef446dcf4cc79fc1f11 272 SUPERFAMILY SSF47413 6 67 8.45E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_18905 a7109eacd12cbef446dcf4cc79fc1f11 272 Pfam PF13560 Helix-turn-helix domain 10 69 1.3E-12 T 12-10-2018 UA74_18905 a7109eacd12cbef446dcf4cc79fc1f11 272 SMART SM00530 13 68 7.2E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_18905 a7109eacd12cbef446dcf4cc79fc1f11 272 Gene3D G3DSA:1.10.260.40 8 84 5.6E-13 T 12-10-2018 UA74_24910 ec9928a33d4b8ef78fbe254523265b1d 375 Pfam PF00355 Rieske [2Fe-2S] domain 265 347 6.7E-11 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_24910 ec9928a33d4b8ef78fbe254523265b1d 375 SUPERFAMILY SSF50022 290 373 1.83E-24 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_24910 ec9928a33d4b8ef78fbe254523265b1d 375 Gene3D G3DSA:2.102.10.10 211 371 2.5E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_03620 94106ccbe62499e6fa3062a6d1cd7201 206 SUPERFAMILY SSF50715 11 179 1.69E-47 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_03620 94106ccbe62499e6fa3062a6d1cd7201 206 Gene3D G3DSA:2.40.240.10 1 96 1.9E-25 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_03620 94106ccbe62499e6fa3062a6d1cd7201 206 Pfam PF01386 Ribosomal L25p family 6 93 8.2E-24 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 UA74_03620 94106ccbe62499e6fa3062a6d1cd7201 206 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 181 24.718 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 UA74_03620 94106ccbe62499e6fa3062a6d1cd7201 206 Gene3D G3DSA:2.170.120.20 97 181 8.3E-14 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal UA74_03620 94106ccbe62499e6fa3062a6d1cd7201 206 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 8 92 6.0E-19 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 UA74_03620 94106ccbe62499e6fa3062a6d1cd7201 206 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 177 2.3E-47 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 UA74_03620 94106ccbe62499e6fa3062a6d1cd7201 206 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 101 179 5.9E-17 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain UA74_22770 33bcdb4f7c2b5110539d29732d3b9633 340 ProSitePatterns PS01322 Phosphotriesterase family signature 1. 17 25 - T 12-10-2018 IPR017947 Aryldialkylphosphatase, zinc-binding site GO:0008270|GO:0009056|GO:0016788 UA74_22770 33bcdb4f7c2b5110539d29732d3b9633 340 Pfam PF02126 Phosphotriesterase family 13 318 1.7E-91 T 12-10-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 UA74_22770 33bcdb4f7c2b5110539d29732d3b9633 340 Gene3D G3DSA:3.20.20.140 3 319 1.9E-104 T 12-10-2018 UA74_22770 33bcdb4f7c2b5110539d29732d3b9633 340 SUPERFAMILY SSF51556 3 319 3.81E-81 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_02520 9d49c14e8cb395134670ce7bd5c9814b 106 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 17 105 1.3E-43 T 12-10-2018 IPR009359 Phenylacetic acid degradation B UA74_02520 9d49c14e8cb395134670ce7bd5c9814b 106 Pfam PF06243 Phenylacetic acid degradation B 17 102 7.6E-38 T 12-10-2018 IPR009359 Phenylacetic acid degradation B UA74_02520 9d49c14e8cb395134670ce7bd5c9814b 106 PIRSF PIRSF030200 5 106 2.1E-42 T 12-10-2018 IPR009359 Phenylacetic acid degradation B UA74_02520 9d49c14e8cb395134670ce7bd5c9814b 106 Gene3D G3DSA:3.10.20.520 11 76 9.2E-31 T 12-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B UA74_11840 dcd740576e3a9003ebb7931a18c2bea8 421 Gene3D G3DSA:3.40.190.10 31 367 9.3E-122 T 12-10-2018 UA74_11840 dcd740576e3a9003ebb7931a18c2bea8 421 SUPERFAMILY SSF53850 28 419 2.82E-56 T 12-10-2018 UA74_11840 dcd740576e3a9003ebb7931a18c2bea8 421 Pfam PF13416 Bacterial extracellular solute-binding protein 50 348 1.3E-31 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_11840 dcd740576e3a9003ebb7931a18c2bea8 421 Gene3D G3DSA:3.40.190.10 142 412 9.3E-122 T 12-10-2018 UA74_16815 e8eda669ea2dcf7bb0ced094ff6280e9 143 Gene3D G3DSA:3.10.450.50 5 142 2.1E-30 T 12-10-2018 UA74_16815 e8eda669ea2dcf7bb0ced094ff6280e9 143 SUPERFAMILY SSF54427 16 141 2.2E-27 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_16815 e8eda669ea2dcf7bb0ced094ff6280e9 143 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 16 139 2.9E-24 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 UA74_16815 e8eda669ea2dcf7bb0ced094ff6280e9 143 Pfam PF14534 Domain of unknown function (DUF4440) 20 132 3.1E-10 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 UA74_13310 e6a50b5bafde63d92d573c1e83bcec84 332 Gene3D G3DSA:3.40.50.2300 143 280 1.6E-48 T 12-10-2018 UA74_13310 e6a50b5bafde63d92d573c1e83bcec84 332 Gene3D G3DSA:3.40.50.2300 44 308 1.6E-48 T 12-10-2018 UA74_13310 e6a50b5bafde63d92d573c1e83bcec84 332 Pfam PF13407 Periplasmic binding protein domain 40 300 2.9E-34 T 12-10-2018 IPR025997 Periplasmic binding protein UA74_13310 e6a50b5bafde63d92d573c1e83bcec84 332 SUPERFAMILY SSF53822 37 312 2.86E-49 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_00845 cbda4f08a08010ea4d4bbd195aa330b0 622 SUPERFAMILY SSF49265 58 143 3.12E-8 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 UA74_00845 cbda4f08a08010ea4d4bbd195aa330b0 622 Gene3D G3DSA:2.60.40.10 55 153 1.1E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_00845 cbda4f08a08010ea4d4bbd195aa330b0 622 SMART SM00060 59 139 4.3E-7 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 UA74_13165 46976a63677165a07f6073e3858323a1 177 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 6 172 30.456 T 12-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 UA74_13165 46976a63677165a07f6073e3858323a1 177 Pfam PF00156 Phosphoribosyl transferase domain 42 150 4.3E-15 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_13165 46976a63677165a07f6073e3858323a1 177 SUPERFAMILY SSF53271 13 164 3.15E-40 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_13165 46976a63677165a07f6073e3858323a1 177 Gene3D G3DSA:3.40.50.2020 2 172 6.7E-51 T 12-10-2018 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 SUPERFAMILY SSF81301 72 364 1.01E-51 T 12-10-2018 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Gene3D G3DSA:3.30.460.100 638 883 1.2E-59 T 12-10-2018 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Gene3D G3DSA:3.30.460.100 95 361 1.2E-51 T 12-10-2018 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 SUPERFAMILY SSF81593 894 1045 2.04E-36 T 12-10-2018 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 83 1035 16.481 T 12-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 SUPERFAMILY SSF81593 371 525 7.14E-34 T 12-10-2018 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 SUPERFAMILY SSF81301 601 887 3.01E-64 T 12-10-2018 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Gene3D G3DSA:1.20.120.330 370 526 3.5E-38 T 12-10-2018 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Gene3D G3DSA:1.20.120.330 892 1046 1.8E-37 T 12-10-2018 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Pfam PF08335 GlnD PII-uridylyltransferase 901 1043 3.3E-23 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Pfam PF08335 GlnD PII-uridylyltransferase 378 524 1.3E-32 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 629 878 5.7E-60 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 UA74_25125 a6d0cbb9b7a5816b1ab2eb0c8d93a2bc 1047 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 86 355 7.1E-36 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 UA74_11600 4501ca6e73d5e55a483200a15cb79967 182 ProSitePatterns PS01081 TetR-type HTH domain signature. 16 46 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_11600 4501ca6e73d5e55a483200a15cb79967 182 Gene3D G3DSA:1.10.357.10 1 178 2.1E-33 T 12-10-2018 UA74_11600 4501ca6e73d5e55a483200a15cb79967 182 SUPERFAMILY SSF46689 2 69 5.99E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_11600 4501ca6e73d5e55a483200a15cb79967 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 4 17 2.5E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_11600 4501ca6e73d5e55a483200a15cb79967 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 47 2.5E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_11600 4501ca6e73d5e55a483200a15cb79967 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 4 48 5.8E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_12690 c724c884643f15dd26a4c35d69bd926e 283 SUPERFAMILY SSF55729 1 246 9.75E-12 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_12690 c724c884643f15dd26a4c35d69bd926e 283 Gene3D G3DSA:3.40.630.30 2 221 5.8E-12 T 12-10-2018 UA74_00275 6169559c3af885a2d08dde08725655f1 544 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 213 530 2.8E-52 T 12-10-2018 IPR019993 RecB family nuclease, TM0106, putative UA74_00275 6169559c3af885a2d08dde08725655f1 544 Pfam PF13482 RNase_H superfamily 445 530 9.2E-11 T 12-10-2018 IPR038720 YprB, ribonuclease H-like domain UA74_00275 6169559c3af885a2d08dde08725655f1 544 SUPERFAMILY SSF53098 449 536 1.52E-5 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 Gene3D G3DSA:3.50.50.60 117 244 6.7E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 Gene3D G3DSA:3.50.50.60 7 301 6.7E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 Pfam PF04324 BFD-like [2Fe-2S] binding domain 425 469 8.3E-10 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 SUPERFAMILY SSF51905 154 309 1.09E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 2.9E-16 T 12-10-2018 UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 2.9E-16 T 12-10-2018 UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.9E-16 T 12-10-2018 UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.9E-16 T 12-10-2018 UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.9E-9 T 12-10-2018 UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 2.9E-9 T 12-10-2018 UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 2.9E-9 T 12-10-2018 UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 2.9E-9 T 12-10-2018 UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 SUPERFAMILY SSF51905 3 199 1.81E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 301 5.2E-48 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_09380 336b3af860733f03575e1c73e5a9fe9d 487 Gene3D G3DSA:1.10.10.1100 417 480 5.7E-9 T 12-10-2018 UA74_12925 bb82f15b8f517f15ea0830d680adbed6 135 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 98 19.846 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 UA74_12925 bb82f15b8f517f15ea0830d680adbed6 135 Pfam PF02416 mttA/Hcf106 family 4 54 7.8E-14 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 Gene3D G3DSA:3.30.420.40 154 314 8.3E-76 T 12-10-2018 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 Gene3D G3DSA:3.90.640.10 192 269 8.3E-76 T 12-10-2018 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 286 300 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 SUPERFAMILY SSF53067 155 325 2.66E-27 T 12-10-2018 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 283 299 6.0E-7 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 166 176 6.0E-7 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 314 334 6.0E-7 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 2 15 6.0E-7 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 PRINTS PR00301 70kDa heat shock protein signature 107 127 6.0E-7 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 Gene3D G3DSA:3.30.420.40 4 324 8.3E-76 T 12-10-2018 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 SUPERFAMILY SSF53067 4 146 4.86E-20 T 12-10-2018 UA74_19015 9830fe66b4ae1c4eacc09d327c5e112c 589 Pfam PF00012 Hsp70 protein 102 324 1.9E-23 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_14715 ccddbd54146a9cb0ec99984882e80ba7 467 Pfam PF11700 Vacuole effluxer Atg22 like 19 459 4.2E-94 T 12-10-2018 IPR024671 Autophagy-related protein 22-like UA74_14715 ccddbd54146a9cb0ec99984882e80ba7 467 SUPERFAMILY SSF103473 24 454 4.32E-40 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_14715 ccddbd54146a9cb0ec99984882e80ba7 467 Gene3D G3DSA:1.20.1250.20 30 451 9.5E-33 T 12-10-2018 UA74_27100 ed873753d1eed1b4cc7f99f5cc68d79f 359 Pfam PF02653 Branched-chain amino acid transport system / permease component 81 346 8.9E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_15535 33b2ddc22b95f0cbc5698055e35b9601 311 Pfam PF00248 Aldo/keto reductase family 15 295 6.8E-63 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_15535 33b2ddc22b95f0cbc5698055e35b9601 311 PRINTS PR00069 Aldo-keto reductase signature 39 63 5.4E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_15535 33b2ddc22b95f0cbc5698055e35b9601 311 PRINTS PR00069 Aldo-keto reductase signature 242 266 5.4E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_15535 33b2ddc22b95f0cbc5698055e35b9601 311 PRINTS PR00069 Aldo-keto reductase signature 103 121 5.4E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_15535 33b2ddc22b95f0cbc5698055e35b9601 311 Gene3D G3DSA:3.20.20.100 1 310 8.7E-98 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_15535 33b2ddc22b95f0cbc5698055e35b9601 311 SUPERFAMILY SSF51430 1 309 1.57E-86 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 SMART SM00448 6 121 3.0E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 SUPERFAMILY SSF52172 5 137 3.84E-32 T 12-10-2018 IPR011006 CheY-like superfamily UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 SMART SM00421 158 215 6.8E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 Pfam PF00072 Response regulator receiver domain 8 122 3.4E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 2.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 2.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 2.9E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 Gene3D G3DSA:3.40.50.12740 6 221 3.4E-66 T 12-10-2018 UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 SUPERFAMILY SSF46894 148 220 1.7E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_17810 0632c5396ef4ff27ba9621bf9e92c485 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 1.7E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_04955 d344d5a88759037b75f11da5dacf3455 352 Gene3D G3DSA:3.30.530.20 179 351 4.5E-17 T 12-10-2018 IPR023393 START-like domain superfamily UA74_04955 d344d5a88759037b75f11da5dacf3455 352 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 25 141 1.1E-19 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_04955 d344d5a88759037b75f11da5dacf3455 352 SUPERFAMILY SSF55961 7 149 2.55E-36 T 12-10-2018 UA74_04955 d344d5a88759037b75f11da5dacf3455 352 Gene3D G3DSA:3.30.530.20 2 171 2.6E-42 T 12-10-2018 IPR023393 START-like domain superfamily UA74_04955 d344d5a88759037b75f11da5dacf3455 352 SUPERFAMILY SSF55961 174 351 1.91E-14 T 12-10-2018 UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 Gene3D G3DSA:3.30.450.20 2 112 4.9E-7 T 12-10-2018 UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 Pfam PF08447 PAS fold 138 225 1.3E-11 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 Gene3D G3DSA:3.30.450.20 126 236 9.7E-19 T 12-10-2018 UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 SUPERFAMILY SSF55785 126 230 1.92E-13 T 12-10-2018 IPR035965 PAS domain superfamily UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 Pfam PF00990 Diguanylate cyclase, GGDEF domain 245 395 3.4E-39 T 12-10-2018 IPR000160 GGDEF domain UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 Pfam PF00989 PAS fold 9 65 3.1E-5 T 12-10-2018 IPR013767 PAS fold GO:0006355 UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 SUPERFAMILY SSF55785 5 96 5.23E-8 T 12-10-2018 IPR035965 PAS domain superfamily UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 SMART SM00091 6 72 5.3E-4 T 12-10-2018 IPR000014 PAS domain UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 SMART SM00091 117 182 52.0 T 12-10-2018 IPR000014 PAS domain UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 239 399 2.5E-40 T 12-10-2018 IPR000160 GGDEF domain UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 SUPERFAMILY SSF55073 248 401 3.37E-44 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 SMART SM00052 409 652 1.9E-66 T 12-10-2018 IPR001633 EAL domain UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 SMART SM00267 232 399 3.9E-53 T 12-10-2018 IPR000160 GGDEF domain UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 Pfam PF00563 EAL domain 415 647 7.0E-64 T 12-10-2018 IPR001633 EAL domain UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 Gene3D G3DSA:3.20.20.450 410 657 5.5E-76 T 12-10-2018 IPR035919 EAL domain superfamily UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 Gene3D G3DSA:3.30.70.270 241 409 8.3E-52 T 12-10-2018 UA74_14730 e8be8f3c95d2dd2cbd5a402022154c06 663 SUPERFAMILY SSF141868 415 656 3.27E-70 T 12-10-2018 IPR035919 EAL domain superfamily UA74_04430 36cd19da399dcc875ab7c33ef9b29431 376 SUPERFAMILY SSF53187 28 375 7.11E-41 T 12-10-2018 UA74_04430 36cd19da399dcc875ab7c33ef9b29431 376 SUPERFAMILY SSF55031 191 292 2.84E-18 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UA74_04430 36cd19da399dcc875ab7c33ef9b29431 376 Pfam PF07687 Peptidase dimerisation domain 191 288 4.7E-12 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain UA74_04430 36cd19da399dcc875ab7c33ef9b29431 376 Gene3D G3DSA:3.30.70.360 191 299 7.4E-95 T 12-10-2018 UA74_04430 36cd19da399dcc875ab7c33ef9b29431 376 Pfam PF01546 Peptidase family M20/M25/M40 87 375 3.0E-21 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 UA74_04430 36cd19da399dcc875ab7c33ef9b29431 376 Gene3D G3DSA:3.40.630.10 36 365 7.4E-95 T 12-10-2018 UA74_04430 36cd19da399dcc875ab7c33ef9b29431 376 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 26 375 4.1E-154 T 12-10-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 UA74_22165 4cd47e01beba96970a0053cf7e43e28f 328 Pfam PF13377 Periplasmic binding protein-like domain 165 323 3.3E-36 T 12-10-2018 UA74_22165 4cd47e01beba96970a0053cf7e43e28f 328 SMART SM00354 2 72 1.0E-26 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_22165 4cd47e01beba96970a0053cf7e43e28f 328 Gene3D G3DSA:3.40.50.2300 157 282 1.2E-69 T 12-10-2018 UA74_22165 4cd47e01beba96970a0053cf7e43e28f 328 SUPERFAMILY SSF53822 62 325 7.26E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_22165 4cd47e01beba96970a0053cf7e43e28f 328 Gene3D G3DSA:3.40.50.2300 56 298 1.2E-69 T 12-10-2018 UA74_22165 4cd47e01beba96970a0053cf7e43e28f 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 5.5E-15 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_22165 4cd47e01beba96970a0053cf7e43e28f 328 SUPERFAMILY SSF47413 3 59 2.73E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_22165 4cd47e01beba96970a0053cf7e43e28f 328 Gene3D G3DSA:1.10.260.40 1 55 5.3E-23 T 12-10-2018 UA74_24000 8af0940a6e5f35a1a2ed8b77a94a5fbc 267 Pfam PF01614 Bacterial transcriptional regulator 127 249 4.0E-22 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_24000 8af0940a6e5f35a1a2ed8b77a94a5fbc 267 SMART SM00346 7 97 2.3E-9 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_24000 8af0940a6e5f35a1a2ed8b77a94a5fbc 267 SUPERFAMILY SSF55781 81 254 4.32E-35 T 12-10-2018 UA74_24000 8af0940a6e5f35a1a2ed8b77a94a5fbc 267 Gene3D G3DSA:1.10.10.10 2 75 5.9E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24000 8af0940a6e5f35a1a2ed8b77a94a5fbc 267 SUPERFAMILY SSF46785 7 77 2.69E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24000 8af0940a6e5f35a1a2ed8b77a94a5fbc 267 Pfam PF09339 IclR helix-turn-helix domain 10 59 5.2E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_24000 8af0940a6e5f35a1a2ed8b77a94a5fbc 267 Gene3D G3DSA:3.30.450.40 87 255 4.1E-38 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_27560 385d375dcb2d53edda2b2e6cc4b6d5ce 405 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 389 7.6E-71 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_27560 385d375dcb2d53edda2b2e6cc4b6d5ce 405 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 271 290 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 UA74_27560 385d375dcb2d53edda2b2e6cc4b6d5ce 405 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 404 1.9E-210 T 12-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 UA74_27560 385d375dcb2d53edda2b2e6cc4b6d5ce 405 SMART SM01329 9 396 6.7E-137 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_27560 385d375dcb2d53edda2b2e6cc4b6d5ce 405 Gene3D G3DSA:3.40.718.10 1 405 1.4E-215 T 12-10-2018 UA74_27560 385d375dcb2d53edda2b2e6cc4b6d5ce 405 SUPERFAMILY SSF53659 2 404 1.56E-150 T 12-10-2018 UA74_27560 385d375dcb2d53edda2b2e6cc4b6d5ce 405 PIRSF PIRSF000108 1 405 2.6E-221 T 12-10-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 UA74_21220 ea57312398085e6059984de2bb7b256d 424 Pfam PF01593 Flavin containing amine oxidoreductase 13 281 2.2E-21 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_21220 ea57312398085e6059984de2bb7b256d 424 Gene3D G3DSA:3.50.50.60 6 281 1.7E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_21220 ea57312398085e6059984de2bb7b256d 424 Gene3D G3DSA:1.10.405.10 114 204 1.7E-26 T 12-10-2018 UA74_21220 ea57312398085e6059984de2bb7b256d 424 SUPERFAMILY SSF51905 6 419 3.7E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_21220 ea57312398085e6059984de2bb7b256d 424 Gene3D G3DSA:3.90.660.10 40 215 1.7E-26 T 12-10-2018 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 189 280 7.1E-27 T 12-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 Gene3D G3DSA:3.40.190.10 2 182 3.1E-58 T 12-10-2018 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 Gene3D G3DSA:3.40.190.10 91 178 3.1E-58 T 12-10-2018 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 Pfam PF08029 HisG, C-terminal domain 206 276 1.0E-23 T 12-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 SUPERFAMILY SSF53850 1 206 2.02E-58 T 12-10-2018 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 2.1E-49 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 Pfam PF01634 ATP phosphoribosyltransferase 49 201 3.1E-37 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 281 30.02 T 12-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 SUPERFAMILY SSF54913 209 280 1.22E-19 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta UA74_12805 ba6eafe9a4bc05323843fbde143adfef 281 Gene3D G3DSA:3.30.70.120 209 275 7.4E-26 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 SMART SM00344 7 116 2.9E-30 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.5E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.5E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.5E-11 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 Gene3D G3DSA:3.30.70.920 61 143 2.9E-17 T 12-10-2018 UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 Pfam PF01037 Lrp/AsnC ligand binding domain 75 146 3.1E-11 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 6.5E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 SUPERFAMILY SSF46785 7 66 4.29E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 SUPERFAMILY SSF54909 70 154 2.15E-11 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_10125 5a1d1443a8535ae5ab1adc749ac9b427 160 Gene3D G3DSA:1.10.10.10 1 60 6.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19365 3c4f0b57077754333594b9a85783d558 211 SUPERFAMILY SSF46689 2 85 2.1E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_19365 3c4f0b57077754333594b9a85783d558 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_19365 3c4f0b57077754333594b9a85783d558 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 9.4E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_19365 3c4f0b57077754333594b9a85783d558 211 Gene3D G3DSA:1.10.357.10 73 198 4.1E-28 T 12-10-2018 UA74_19365 3c4f0b57077754333594b9a85783d558 211 SUPERFAMILY SSF48498 82 195 1.22E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_19365 3c4f0b57077754333594b9a85783d558 211 Gene3D G3DSA:1.10.10.60 2 68 2.6E-29 T 12-10-2018 UA74_10460 1921d34775a821016003a5ec2ddff31d 229 SUPERFAMILY SSF53597 3 222 1.7E-46 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_10460 1921d34775a821016003a5ec2ddff31d 229 Pfam PF01872 RibD C-terminal domain 5 214 2.9E-40 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_10460 1921d34775a821016003a5ec2ddff31d 229 Gene3D G3DSA:3.40.430.10 1 226 3.1E-56 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_15490 174d00f35cf4a265ff48afc43a16b9a6 267 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 140 1.5E-10 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UA74_15490 174d00f35cf4a265ff48afc43a16b9a6 267 Gene3D G3DSA:3.40.50.720 1 142 3.8E-27 T 12-10-2018 UA74_15490 174d00f35cf4a265ff48afc43a16b9a6 267 PIRSF PIRSF000103 1 267 7.9E-27 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_15490 174d00f35cf4a265ff48afc43a16b9a6 267 Gene3D G3DSA:1.10.1040.10 143 267 2.2E-31 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_15490 174d00f35cf4a265ff48afc43a16b9a6 267 SUPERFAMILY SSF51735 1 142 9.69E-17 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_28035 3a9e3f4a7b5fb1e7444f8d897fda0678 215 SUPERFAMILY SSF54211 91 215 9.1E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_28035 3a9e3f4a7b5fb1e7444f8d897fda0678 215 Gene3D G3DSA:3.30.230.10 88 215 1.7E-48 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_28035 3a9e3f4a7b5fb1e7444f8d897fda0678 215 Pfam PF00380 Ribosomal protein S9/S16 95 215 5.7E-43 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 UA74_28035 3a9e3f4a7b5fb1e7444f8d897fda0678 215 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 86 215 32.278 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid UA74_28035 3a9e3f4a7b5fb1e7444f8d897fda0678 215 ProSitePatterns PS00360 Ribosomal protein S9 signature. 154 172 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 UA74_06500 327dc7b6615ec87094cbf1ce6b6e4b43 72 SMART SM00923 3 53 1.2E-5 T 12-10-2018 IPR005153 MbtH-like domain UA74_06500 327dc7b6615ec87094cbf1ce6b6e4b43 72 Gene3D G3DSA:3.90.820.10 1 59 8.5E-16 T 12-10-2018 UA74_06500 327dc7b6615ec87094cbf1ce6b6e4b43 72 Pfam PF03621 MbtH-like protein 1 51 4.1E-13 T 12-10-2018 IPR005153 MbtH-like domain UA74_06500 327dc7b6615ec87094cbf1ce6b6e4b43 72 SUPERFAMILY SSF160582 1 56 3.66E-14 T 12-10-2018 IPR038020 MbtH-like domain superfamily UA74_09800 ca274a1d58895ec49e5232f3374563d0 243 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 202 23.856 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 UA74_09800 ca274a1d58895ec49e5232f3374563d0 243 PIRSF PIRSF006755 1 212 7.9E-38 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 UA74_09800 ca274a1d58895ec49e5232f3374563d0 243 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 169 2.1E-31 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 UA74_09800 ca274a1d58895ec49e5232f3374563d0 243 Pfam PF13500 AAA domain 4 201 2.2E-33 T 12-10-2018 UA74_09800 ca274a1d58895ec49e5232f3374563d0 243 SUPERFAMILY SSF52540 1 201 1.22E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_09800 ca274a1d58895ec49e5232f3374563d0 243 Gene3D G3DSA:3.40.50.300 2 224 8.1E-59 T 12-10-2018 UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 285 297 1.1E-10 T 12-10-2018 UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 319 343 1.1E-10 T 12-10-2018 UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 214 1.1E-10 T 12-10-2018 UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 221 235 1.1E-10 T 12-10-2018 UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 SUPERFAMILY SSF53335 164 479 2.37E-46 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 SUPERFAMILY SSF116734 513 653 1.96E-7 T 12-10-2018 UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 Pfam PF02384 N-6 DNA Methylase 198 413 3.9E-31 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 288 294 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 Gene3D G3DSA:3.40.50.150 182 434 2.3E-39 T 12-10-2018 UA74_20555 f484ebafbcede0dfccbcef254029d20f 676 Gene3D G3DSA:3.90.220.20 504 667 1.4E-5 T 12-10-2018 UA74_08835 1aedc836bcc99acbe5d4bcc0353e0725 187 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 14 180 23.991 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 UA74_08835 1aedc836bcc99acbe5d4bcc0353e0725 187 Gene3D G3DSA:2.30.30.240 106 186 9.1E-14 T 12-10-2018 UA74_08835 1aedc836bcc99acbe5d4bcc0353e0725 187 Pfam PF05239 PRC-barrel domain 107 180 1.2E-9 T 12-10-2018 IPR027275 PRC-barrel domain UA74_08835 1aedc836bcc99acbe5d4bcc0353e0725 187 SUPERFAMILY SSF50447 14 103 9.06E-17 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_08835 1aedc836bcc99acbe5d4bcc0353e0725 187 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 15 180 5.2E-39 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 UA74_08835 1aedc836bcc99acbe5d4bcc0353e0725 187 Gene3D G3DSA:2.40.30.60 14 102 2.4E-21 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 UA74_08835 1aedc836bcc99acbe5d4bcc0353e0725 187 Pfam PF01782 RimM N-terminal domain 17 99 1.0E-19 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 UA74_08835 1aedc836bcc99acbe5d4bcc0353e0725 187 SUPERFAMILY SSF50346 110 180 9.68E-17 T 12-10-2018 IPR011033 PRC-barrel-like superfamily UA74_22630 903829b6ec0ea9c601939ecb28e2fd83 542 Gene3D G3DSA:3.40.605.10 56 537 9.2E-195 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_22630 903829b6ec0ea9c601939ecb28e2fd83 542 Gene3D G3DSA:3.40.309.10 281 472 9.2E-195 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_22630 903829b6ec0ea9c601939ecb28e2fd83 542 SUPERFAMILY SSF53720 36 534 6.41E-92 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_22630 903829b6ec0ea9c601939ecb28e2fd83 542 Pfam PF00171 Aldehyde dehydrogenase family 32 445 2.3E-42 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_27635 7433e316a0b43976855d3485bcfed076 645 Gene3D G3DSA:3.30.70.270 150 310 1.8E-16 T 12-10-2018 UA74_27635 7433e316a0b43976855d3485bcfed076 645 Pfam PF00817 impB/mucB/samB family 100 229 9.5E-15 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_27635 7433e316a0b43976855d3485bcfed076 645 Gene3D G3DSA:2.30.40.20 111 149 1.8E-16 T 12-10-2018 UA74_27635 7433e316a0b43976855d3485bcfed076 645 SUPERFAMILY SSF56672 85 310 1.42E-35 T 12-10-2018 UA74_27635 7433e316a0b43976855d3485bcfed076 645 Gene3D G3DSA:1.10.150.20 246 304 1.8E-16 T 12-10-2018 UA74_21255 77bfa6e49cb02256b3275f837a3ba749 426 Gene3D G3DSA:3.90.1230.10 225 331 1.7E-151 T 12-10-2018 UA74_21255 77bfa6e49cb02256b3275f837a3ba749 426 Gene3D G3DSA:3.90.440.10 111 224 1.7E-151 T 12-10-2018 UA74_21255 77bfa6e49cb02256b3275f837a3ba749 426 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 94 101 - T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_21255 77bfa6e49cb02256b3275f837a3ba749 426 Gene3D G3DSA:3.90.340.10 36 386 1.7E-151 T 12-10-2018 UA74_21255 77bfa6e49cb02256b3275f837a3ba749 426 Pfam PF02898 Nitric oxide synthase, oxygenase domain 35 392 5.9E-154 T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_21255 77bfa6e49cb02256b3275f837a3ba749 426 SUPERFAMILY SSF56512 17 394 1.31E-157 T 12-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_30065 6b5cdb7e6b3763987383e78e77541b02 139 Gene3D G3DSA:1.10.1660.10 8 130 8.3E-27 T 12-10-2018 UA74_30065 6b5cdb7e6b3763987383e78e77541b02 139 Pfam PF13411 MerR HTH family regulatory protein 9 73 7.3E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_30065 6b5cdb7e6b3763987383e78e77541b02 139 SMART SM00422 8 78 1.8E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_30065 6b5cdb7e6b3763987383e78e77541b02 139 SUPERFAMILY SSF46955 8 123 2.89E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_06920 c691f9c37d2ff03ceaffb4e6bfd210e0 362 Pfam PF01979 Amidohydrolase family 54 359 1.5E-11 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_06920 c691f9c37d2ff03ceaffb4e6bfd210e0 362 SUPERFAMILY SSF51556 58 323 5.3E-36 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_06920 c691f9c37d2ff03ceaffb4e6bfd210e0 362 Gene3D G3DSA:3.40.50.10910 122 235 8.0E-40 T 12-10-2018 UA74_06920 c691f9c37d2ff03ceaffb4e6bfd210e0 362 Gene3D G3DSA:3.30.110.90 57 324 8.0E-40 T 12-10-2018 UA74_06920 c691f9c37d2ff03ceaffb4e6bfd210e0 362 Gene3D G3DSA:1.20.58.520 236 305 8.0E-40 T 12-10-2018 UA74_06920 c691f9c37d2ff03ceaffb4e6bfd210e0 362 Gene3D G3DSA:2.30.40.10 42 358 8.0E-40 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 Gene3D G3DSA:3.90.180.10 9 358 1.5E-116 T 12-10-2018 UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 SUPERFAMILY SSF50129 310 360 1.18E-7 T 12-10-2018 IPR011032 GroES-like superfamily UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 SUPERFAMILY SSF51735 156 326 1.06E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 7.5E-203 T 12-10-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase MetaCyc: PWY-7908 UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 Gene3D G3DSA:3.40.50.720 167 304 1.5E-116 T 12-10-2018 UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 Pfam PF00107 Zinc-binding dehydrogenase 190 320 7.9E-29 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 SUPERFAMILY SSF50129 3 186 1.83E-55 T 12-10-2018 IPR011032 GroES-like superfamily UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 2.0E-28 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_11325 1f5f0967d358712259bfb6d7994f876d 361 SMART SM00829 12 361 9.1E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_21410 78725a2524c13a371daa7c2c6ae43c85 166 SMART SM00507 48 102 7.9E-5 T 12-10-2018 IPR003615 HNH nuclease UA74_21410 78725a2524c13a371daa7c2c6ae43c85 166 Gene3D G3DSA:3.30.40.60 10 133 6.6E-17 T 12-10-2018 UA74_21410 78725a2524c13a371daa7c2c6ae43c85 166 Pfam PF14279 HNH endonuclease 61 106 2.5E-9 T 12-10-2018 IPR029471 HNH endonuclease 5 UA74_28215 67cead7f2c10a7949510ba652b723711 303 Pfam PF00005 ABC transporter 21 161 5.5E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_28215 67cead7f2c10a7949510ba652b723711 303 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_28215 67cead7f2c10a7949510ba652b723711 303 SUPERFAMILY SSF52540 5 223 1.81E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28215 67cead7f2c10a7949510ba652b723711 303 SMART SM00382 30 209 1.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28215 67cead7f2c10a7949510ba652b723711 303 Gene3D G3DSA:3.40.50.300 1 229 8.6E-63 T 12-10-2018 UA74_28215 67cead7f2c10a7949510ba652b723711 303 Pfam PF13732 Domain of unknown function (DUF4162) 215 297 3.6E-9 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 PIRSF PIRSF000538 2 504 2.0E-168 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 Hamap MF_00186 Glycerol kinase [glpK]. 2 500 55.554 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 453 1.4E-64 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 SUPERFAMILY SSF53067 3 257 6.05E-88 T 12-10-2018 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 499 1.2E-224 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 SUPERFAMILY SSF53067 257 500 4.07E-83 T 12-10-2018 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 Gene3D G3DSA:3.30.420.40 256 504 1.9E-94 T 12-10-2018 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 Gene3D G3DSA:3.30.420.40 2 255 6.0E-109 T 12-10-2018 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 254 7.1E-74 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UA74_26980 4bce5c56a21e599cbb401be76c8ad8bd 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_14285 8e2581627a2004b0b9b3f912d7a16e7e 413 Gene3D G3DSA:1.20.1250.20 19 199 6.2E-26 T 12-10-2018 UA74_14285 8e2581627a2004b0b9b3f912d7a16e7e 413 SUPERFAMILY SSF103473 6 392 1.44E-56 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_14285 8e2581627a2004b0b9b3f912d7a16e7e 413 Pfam PF07690 Major Facilitator Superfamily 25 278 2.6E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_14285 8e2581627a2004b0b9b3f912d7a16e7e 413 Gene3D G3DSA:1.20.1250.20 211 400 6.1E-15 T 12-10-2018 UA74_17120 ea0ef8db1ca81d6171cb325385dbf917 266 SUPERFAMILY SSF53474 4 264 9.89E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17120 ea0ef8db1ca81d6171cb325385dbf917 266 Pfam PF00975 Thioesterase domain 18 123 1.9E-29 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_17120 ea0ef8db1ca81d6171cb325385dbf917 266 Gene3D G3DSA:3.40.50.1820 2 263 1.7E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17120 ea0ef8db1ca81d6171cb325385dbf917 266 SMART SM00824 Thioesterase 20 184 1.6E-5 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_10440 276958e68be858837a69246319e26fec 440 SUPERFAMILY SSF51735 4 185 1.81E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_10440 276958e68be858837a69246319e26fec 440 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 288 9.2E-32 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_10440 276958e68be858837a69246319e26fec 440 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 414 6.0E-121 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UA74_10440 276958e68be858837a69246319e26fec 440 Gene3D G3DSA:1.20.5.100 197 226 2.1E-12 T 12-10-2018 UA74_10440 276958e68be858837a69246319e26fec 440 Gene3D G3DSA:3.40.50.720 1 196 5.3E-60 T 12-10-2018 UA74_10440 276958e68be858837a69246319e26fec 440 SMART SM00984 316 418 8.4E-35 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_10440 276958e68be858837a69246319e26fec 440 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 418 9.8E-27 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_10440 276958e68be858837a69246319e26fec 440 SUPERFAMILY SSF52413 307 427 7.46E-30 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 UA74_10440 276958e68be858837a69246319e26fec 440 SUPERFAMILY SSF48179 196 293 8.33E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_10440 276958e68be858837a69246319e26fec 440 Gene3D G3DSA:3.40.50.720 227 438 9.7E-63 T 12-10-2018 UA74_10440 276958e68be858837a69246319e26fec 440 PIRSF PIRSF500134 3 435 9.6E-134 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 UA74_10440 276958e68be858837a69246319e26fec 440 PIRSF PIRSF000124 3 433 3.8E-116 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UA74_10440 276958e68be858837a69246319e26fec 440 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 174 8.7E-49 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UA74_10510 8b6dc401beb53ed09bbb6acc1140a5bc 549 Gene3D G3DSA:3.30.450.40 39 175 1.2E-17 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_10510 8b6dc401beb53ed09bbb6acc1140a5bc 549 Gene3D G3DSA:3.30.565.10 417 541 1.3E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_10510 8b6dc401beb53ed09bbb6acc1140a5bc 549 SUPERFAMILY SSF55781 30 191 3.71E-16 T 12-10-2018 UA74_10510 8b6dc401beb53ed09bbb6acc1140a5bc 549 SUPERFAMILY SSF55781 198 344 6.32E-5 T 12-10-2018 UA74_10510 8b6dc401beb53ed09bbb6acc1140a5bc 549 SMART SM00065 44 175 8.8E-4 T 12-10-2018 IPR003018 GAF domain GO:0005515 UA74_10510 8b6dc401beb53ed09bbb6acc1140a5bc 549 Gene3D G3DSA:3.30.450.40 197 349 1.4E-7 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_10510 8b6dc401beb53ed09bbb6acc1140a5bc 549 SUPERFAMILY SSF55874 457 541 1.2E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_10510 8b6dc401beb53ed09bbb6acc1140a5bc 549 Pfam PF07730 Histidine kinase 350 411 1.3E-10 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_10510 8b6dc401beb53ed09bbb6acc1140a5bc 549 Pfam PF13185 GAF domain 43 165 3.3E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 UA74_21075 a8295c1d697bb3751e8f00c26a572de8 292 Gene3D G3DSA:1.10.3720.10 25 283 1.0E-52 T 12-10-2018 IPR035906 MetI-like superfamily UA74_21075 a8295c1d697bb3751e8f00c26a572de8 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 282 2.1E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_21075 a8295c1d697bb3751e8f00c26a572de8 292 SUPERFAMILY SSF161098 27 292 4.11E-61 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08230 cf47c103cadf6119c8ac8edaee02a9d0 716 SMART SM00490 275 356 9.0E-21 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_08230 cf47c103cadf6119c8ac8edaee02a9d0 716 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 36 372 4.1E-68 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 UA74_08230 cf47c103cadf6119c8ac8edaee02a9d0 716 Pfam PF00271 Helicase conserved C-terminal domain 264 355 2.7E-12 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_08230 cf47c103cadf6119c8ac8edaee02a9d0 716 SMART SM00487 33 234 4.4E-21 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_08230 cf47c103cadf6119c8ac8edaee02a9d0 716 Pfam PF00270 DEAD/DEAH box helicase 40 209 1.2E-15 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_08230 cf47c103cadf6119c8ac8edaee02a9d0 716 SUPERFAMILY SSF53271 664 713 3.55E-8 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_08230 cf47c103cadf6119c8ac8edaee02a9d0 716 SUPERFAMILY SSF52540 81 376 7.51E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08230 cf47c103cadf6119c8ac8edaee02a9d0 716 Gene3D G3DSA:3.40.50.300 15 225 2.8E-54 T 12-10-2018 UA74_08230 cf47c103cadf6119c8ac8edaee02a9d0 716 Pfam PF16124 RecQ zinc-binding 454 497 1.9E-5 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain UA74_22045 ba998e24d9d2dc0916b0032aca793b78 137 PRINTS PR00502 NUDIX hydrolase family signature 45 60 2.3E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_22045 ba998e24d9d2dc0916b0032aca793b78 137 PRINTS PR00502 NUDIX hydrolase family signature 31 45 2.3E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_22045 ba998e24d9d2dc0916b0032aca793b78 137 Gene3D G3DSA:3.90.79.10 6 134 1.3E-21 T 12-10-2018 UA74_22045 ba998e24d9d2dc0916b0032aca793b78 137 Pfam PF00293 NUDIX domain 9 122 4.1E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_22045 ba998e24d9d2dc0916b0032aca793b78 137 SUPERFAMILY SSF55811 6 130 1.76E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_08445 440e93dd0b0869260e02630322f63422 290 SUPERFAMILY SSF56655 24 283 2.88E-67 T 12-10-2018 UA74_08445 440e93dd0b0869260e02630322f63422 290 Gene3D G3DSA:3.40.190.80 166 286 3.3E-32 T 12-10-2018 UA74_08445 440e93dd0b0869260e02630322f63422 290 Pfam PF00459 Inositol monophosphatase family 24 252 1.9E-56 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_08445 440e93dd0b0869260e02630322f63422 290 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 234 248 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 UA74_08445 440e93dd0b0869260e02630322f63422 290 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 105 118 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site UA74_08445 440e93dd0b0869260e02630322f63422 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 2.1E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_08445 440e93dd0b0869260e02630322f63422 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 200 221 2.1E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_08445 440e93dd0b0869260e02630322f63422 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 231 255 2.1E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_08445 440e93dd0b0869260e02630322f63422 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 105 121 2.1E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_08445 440e93dd0b0869260e02630322f63422 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 154 177 2.1E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_08445 440e93dd0b0869260e02630322f63422 290 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 82 2.1E-39 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_08445 440e93dd0b0869260e02630322f63422 290 Gene3D G3DSA:3.30.540.10 17 165 4.3E-39 T 12-10-2018 UA74_10380 864489c23f393af4339bdfa395470e9f 325 SUPERFAMILY SSF53756 53 322 3.4E-14 T 12-10-2018 UA74_10380 864489c23f393af4339bdfa395470e9f 325 Pfam PF00534 Glycosyl transferases group 1 219 300 5.4E-7 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_10380 864489c23f393af4339bdfa395470e9f 325 Gene3D G3DSA:3.40.50.2000 201 324 8.5E-11 T 12-10-2018 UA74_00675 92c121210ac543d3648bbf500eac3dcd 397 Pfam PF01266 FAD dependent oxidoreductase 3 389 5.6E-60 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_00675 92c121210ac543d3648bbf500eac3dcd 397 SUPERFAMILY SSF51905 2 392 1.12E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10855 537780f48b961fd38dc8cddfb7445b5d 310 Pfam PF00106 short chain dehydrogenase 16 216 1.3E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10855 537780f48b961fd38dc8cddfb7445b5d 310 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 161 0.0041 T 12-10-2018 UA74_10855 537780f48b961fd38dc8cddfb7445b5d 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 3.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10855 537780f48b961fd38dc8cddfb7445b5d 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 3.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10855 537780f48b961fd38dc8cddfb7445b5d 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 3.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10855 537780f48b961fd38dc8cddfb7445b5d 310 Gene3D G3DSA:3.40.50.720 1 303 2.1E-82 T 12-10-2018 UA74_10855 537780f48b961fd38dc8cddfb7445b5d 310 SUPERFAMILY SSF51735 9 299 4.35E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_27490 2dcb8eb542b797fcfae98783f686cc96 385 SUPERFAMILY SSF53822 86 300 2.24E-6 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_27490 2dcb8eb542b797fcfae98783f686cc96 385 Gene3D G3DSA:3.40.50.2300 75 343 1.0E-86 T 12-10-2018 UA74_27490 2dcb8eb542b797fcfae98783f686cc96 385 Gene3D G3DSA:3.40.50.2300 180 376 1.0E-86 T 12-10-2018 UA74_27490 2dcb8eb542b797fcfae98783f686cc96 385 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 79 381 1.0E-48 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 353 454 2.1E-5 T 12-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Gene3D G3DSA:1.50.10.10 469 818 4.5E-102 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Gene3D G3DSA:2.60.120.260 143 326 2.9E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 820 885 7.8E-9 T 12-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Gene3D G3DSA:2.60.40.10 39 142 1.3E-24 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 461 809 1.7E-37 T 12-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 SUPERFAMILY SSF49265 62 141 2.26E-6 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Gene3D G3DSA:2.60.420.10 461 882 4.5E-102 T 12-10-2018 UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 SUPERFAMILY SSF48208 464 883 3.83E-41 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Gene3D G3DSA:2.60.120.260 339 456 2.1E-10 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_17945 9a0b6d5b46bf6a548c9d6d63c501cc03 927 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 178 323 2.1E-13 T 12-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal UA74_17440 c7cf86e0d2cb84d5b5b9352bc53ccb5a 231 Gene3D G3DSA:1.10.357.10 25 212 4.3E-36 T 12-10-2018 UA74_17440 c7cf86e0d2cb84d5b5b9352bc53ccb5a 231 SUPERFAMILY SSF46689 27 106 2.0E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_17440 c7cf86e0d2cb84d5b5b9352bc53ccb5a 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 82 3.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 541 576 3.2E-8 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 793 826 1.7E-5 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 520 560 8.2E-9 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 709 749 2.3E-10 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 414 443 0.0018 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 499 539 8.0E-6 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 688 723 1.5E-5 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 812 846 0.0031 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 562 602 7.5E-9 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 393 427 8.8E-6 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 464 498 5.1E-7 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 605 644 5.5E-7 T 12-10-2018 IPR006530 YD repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Gene3D G3DSA:2.180.10.10 949 1260 7.7E-39 T 12-10-2018 UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Gene3D G3DSA:2.180.10.10 333 508 7.1E-8 T 12-10-2018 UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Gene3D G3DSA:3.90.930.1 653 797 3.8E-15 T 12-10-2018 UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Gene3D G3DSA:3.90.930.1 511 652 3.6E-13 T 12-10-2018 UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 812 846 1.3E-6 T 12-10-2018 IPR031325 RHS repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 393 425 1.1E-5 T 12-10-2018 IPR031325 RHS repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 464 493 1.6E-5 T 12-10-2018 IPR031325 RHS repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 520 556 1.2E-6 T 12-10-2018 IPR031325 RHS repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 709 746 8.4E-12 T 12-10-2018 IPR031325 RHS repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 562 598 7.9E-8 T 12-10-2018 IPR031325 RHS repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 478 508 4.9E-5 T 12-10-2018 IPR031325 RHS repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF05593 RHS Repeat 605 640 1.1E-7 T 12-10-2018 IPR031325 RHS repeat UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 Pfam PF03527 RHS protein 1159 1191 2.6E-8 T 12-10-2018 IPR001826 RHS protein UA74_24780 46574f558d4a69762f967c2606fef1e7 1345 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1187 1260 2.0E-21 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 UA74_28495 43a9b0c2dbaeed81b6ca8ee625863cd4 280 Pfam PF00005 ABC transporter 24 165 4.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_28495 43a9b0c2dbaeed81b6ca8ee625863cd4 280 Gene3D G3DSA:3.40.50.300 1 271 6.7E-69 T 12-10-2018 UA74_28495 43a9b0c2dbaeed81b6ca8ee625863cd4 280 SUPERFAMILY SSF52540 4 221 3.92E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28495 43a9b0c2dbaeed81b6ca8ee625863cd4 280 SMART SM00382 32 214 3.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28495 43a9b0c2dbaeed81b6ca8ee625863cd4 280 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_19500 45ece54cc9963b9e3c38a34f26615677 115 ProSitePatterns PS00194 Thioredoxin family active site. 30 48 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_19500 45ece54cc9963b9e3c38a34f26615677 115 TIGRFAM TIGR01068 thioredoxin: thioredoxin 14 110 9.6E-34 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_19500 45ece54cc9963b9e3c38a34f26615677 115 SUPERFAMILY SSF52833 6 113 6.86E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_19500 45ece54cc9963b9e3c38a34f26615677 115 Gene3D G3DSA:3.40.30.10 1 114 5.8E-33 T 12-10-2018 UA74_19500 45ece54cc9963b9e3c38a34f26615677 115 Pfam PF00085 Thioredoxin 10 110 2.1E-30 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 UA74_19500 45ece54cc9963b9e3c38a34f26615677 115 PRINTS PR00421 Thioredoxin family signature 37 46 4.3E-7 T 12-10-2018 UA74_19500 45ece54cc9963b9e3c38a34f26615677 115 PRINTS PR00421 Thioredoxin family signature 77 88 4.3E-7 T 12-10-2018 UA74_19500 45ece54cc9963b9e3c38a34f26615677 115 PRINTS PR00421 Thioredoxin family signature 29 37 4.3E-7 T 12-10-2018 UA74_19500 45ece54cc9963b9e3c38a34f26615677 115 PIRSF PIRSF000077 7 113 3.3E-38 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_10130 05b386696fc90e374c4da569b2c5ef91 203 Gene3D G3DSA:3.40.630.30 2 184 2.9E-61 T 12-10-2018 UA74_10130 05b386696fc90e374c4da569b2c5ef91 203 SMART SM01006 21 69 2.1E-13 T 12-10-2018 IPR019432 Siderophore biosynthesis protein, conserved domain UA74_10130 05b386696fc90e374c4da569b2c5ef91 203 Pfam PF13523 Acetyltransferase (GNAT) domain 29 170 8.7E-47 T 12-10-2018 UA74_10130 05b386696fc90e374c4da569b2c5ef91 203 SUPERFAMILY SSF55729 8 182 1.24E-46 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_03800 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.8E-5 T 12-10-2018 UA74_03800 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 3.8E-5 T 12-10-2018 UA74_03800 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 3.8E-5 T 12-10-2018 UA74_03800 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 9.8E-12 T 12-10-2018 UA74_03800 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 9.8E-12 T 12-10-2018 UA74_03800 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 9.8E-12 T 12-10-2018 UA74_03800 f722a4735f33ff4d22080835716cd24b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 9.8E-12 T 12-10-2018 UA74_03800 f722a4735f33ff4d22080835716cd24b 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 338 1.5E-48 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_03800 f722a4735f33ff4d22080835716cd24b 441 SUPERFAMILY SSF51905 8 347 5.11E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_03800 f722a4735f33ff4d22080835716cd24b 441 Gene3D G3DSA:3.50.50.100 7 414 1.0E-116 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.10.129.110 2446 2731 2.5E-111 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM01294 3215 3282 4.1E-6 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM01294 1472 1538 3.3E-6 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:1.10.1200.10 1453 1544 2.8E-32 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:1.10.1200.10 3197 3288 1.2E-34 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF53901 31 404 6.74E-106 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00698 Acyl transferase domain 2101 2411 1.7E-82 T 12-10-2018 IPR014043 Acyl transferase UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00698 Acyl transferase domain 571 890 9.4E-84 T 12-10-2018 IPR014043 Acyl transferase UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF51735 2936 3180 1.07E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00823 Phosphopantetheine attachment site 1470 1542 4.7E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00823 Phosphopantetheine attachment site 3214 3286 5.7E-32 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3241 3256 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1497 1512 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF08659 KR domain 1196 1369 1.3E-51 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF08659 KR domain 2939 3111 1.4E-53 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1196 1371 2.2E-45 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2939 3113 9.1E-48 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.366.10 571 874 1.8E-153 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.366.10 2099 2395 4.7E-154 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF51735 976 1185 2.62E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 4.7E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1825 1940 5.7E-43 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00825 Beta-ketoacyl synthase 36 459 9.8E-218 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00825 Beta-ketoacyl synthase 1569 1993 2.9E-209 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF51735 2733 2913 2.56E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.30.70.3290 485 916 1.8E-153 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF53901 1565 1937 1.96E-98 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.30.70.3290 2019 2438 4.7E-154 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF52151 2098 2381 3.4E-63 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.50.720 2736 3188 2.3E-121 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF55048 697 760 1.26E-6 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.50.720 929 1443 2.6E-162 T 12-10-2018 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 536 1.1E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1943 2069 1.1E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00826 2457 2617 8.1E-81 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2101 2392 7.2E-110 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 573 871 5.2E-108 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF47336 3206 3291 2.22E-23 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF51735 1194 1424 1.53E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF47336 1464 1582 2.49E-21 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF14765 Polyketide synthase dehydratase 2457 2724 1.7E-55 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.5E-90 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1567 1817 3.5E-87 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00550 Phosphopantetheine attachment site 3217 3282 2.9E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF00550 Phosphopantetheine attachment site 1475 1538 1.4E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1730 1746 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF52151 569 862 1.12E-65 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 SUPERFAMILY SSF55048 2221 2283 1.96E-12 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Pfam PF08990 Erythronolide synthase docking 2 25 6.5E-10 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.47.10 25 474 3.6E-186 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17315 4e3f80360f6dd3fe878520c1a7c28cc9 3358 Gene3D G3DSA:3.40.47.10 1563 2012 2.7E-183 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_23825 97ed8586d6943860d0784537cdbba6bb 426 Gene3D G3DSA:3.40.190.10 36 371 1.2E-113 T 12-10-2018 UA74_23825 97ed8586d6943860d0784537cdbba6bb 426 Pfam PF01547 Bacterial extracellular solute-binding protein 47 332 3.0E-30 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_23825 97ed8586d6943860d0784537cdbba6bb 426 Gene3D G3DSA:3.40.190.10 145 420 1.2E-113 T 12-10-2018 UA74_23825 97ed8586d6943860d0784537cdbba6bb 426 SUPERFAMILY SSF53850 23 424 1.25E-56 T 12-10-2018 UA74_22395 af532fee03568433cd6dbc147ab7082f 404 SUPERFAMILY SSF55874 278 390 4.38E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_22395 af532fee03568433cd6dbc147ab7082f 404 Pfam PF07730 Histidine kinase 187 253 1.3E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_22395 af532fee03568433cd6dbc147ab7082f 404 Gene3D G3DSA:3.30.565.10 266 390 7.1E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_00940 26524714f529f8573e326a0eb42e627a 268 Pfam PF00005 ABC transporter 25 183 3.3E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_00940 26524714f529f8573e326a0eb42e627a 268 SUPERFAMILY SSF52540 4 254 6.27E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00940 26524714f529f8573e326a0eb42e627a 268 SMART SM00382 33 232 1.6E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_00940 26524714f529f8573e326a0eb42e627a 268 Gene3D G3DSA:3.40.50.300 1 268 1.8E-76 T 12-10-2018 UA74_00940 26524714f529f8573e326a0eb42e627a 268 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 266 3.5E-7 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_25175 ca7f068b462a0900245f02124abdb18e 287 Pfam PF02548 Ketopantoate hydroxymethyltransferase 25 281 5.2E-109 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UA74_25175 ca7f068b462a0900245f02124abdb18e 287 PIRSF PIRSF000388 17 287 1.3E-110 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UA74_25175 ca7f068b462a0900245f02124abdb18e 287 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 27 287 8.5E-92 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UA74_25175 ca7f068b462a0900245f02124abdb18e 287 Gene3D G3DSA:3.20.20.60 23 286 7.8E-111 T 12-10-2018 UA74_25175 ca7f068b462a0900245f02124abdb18e 287 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 26 286 42.555 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UA74_25175 ca7f068b462a0900245f02124abdb18e 287 SUPERFAMILY SSF51621 25 285 5.1E-103 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UA74_26630 ebfa4f5f4fb641d971bd8a9bfbf04780 303 Gene3D G3DSA:3.90.550.10 17 255 7.7E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_26630 ebfa4f5f4fb641d971bd8a9bfbf04780 303 SUPERFAMILY SSF53448 22 269 1.38E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_26630 ebfa4f5f4fb641d971bd8a9bfbf04780 303 Pfam PF00535 Glycosyl transferase family 2 24 204 1.7E-15 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_20095 c092c3a743e1a29b5114ecc2ccc97f12 254 Gene3D G3DSA:1.10.357.10 93 252 3.8E-38 T 12-10-2018 UA74_20095 c092c3a743e1a29b5114ecc2ccc97f12 254 SUPERFAMILY SSF46689 29 91 5.49E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_20095 c092c3a743e1a29b5114ecc2ccc97f12 254 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 84 5.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_20095 c092c3a743e1a29b5114ecc2ccc97f12 254 SUPERFAMILY SSF48498 103 253 4.0E-28 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_20095 c092c3a743e1a29b5114ecc2ccc97f12 254 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 97 250 2.5E-18 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_20095 c092c3a743e1a29b5114ecc2ccc97f12 254 Gene3D G3DSA:1.10.10.60 12 90 4.1E-25 T 12-10-2018 UA74_29805 edb72aca39265f777ab7582948d7acf7 614 Gene3D G3DSA:1.10.540.10 35 154 3.0E-7 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_29805 edb72aca39265f777ab7582948d7acf7 614 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 30 6.3E-8 T 12-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria UA74_29805 edb72aca39265f777ab7582948d7acf7 614 SUPERFAMILY SSF47203 295 481 6.44E-31 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_29805 edb72aca39265f777ab7582948d7acf7 614 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 291 458 1.0E-13 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_29805 edb72aca39265f777ab7582948d7acf7 614 Gene3D G3DSA:1.20.140.10 296 466 6.7E-32 T 12-10-2018 UA74_29805 edb72aca39265f777ab7582948d7acf7 614 Gene3D G3DSA:2.40.110.10 160 295 7.2E-25 T 12-10-2018 UA74_29805 edb72aca39265f777ab7582948d7acf7 614 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 477 610 4.7E-30 T 12-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain UA74_29805 edb72aca39265f777ab7582948d7acf7 614 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 275 2.2E-17 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UA74_29805 edb72aca39265f777ab7582948d7acf7 614 SUPERFAMILY SSF56645 34 297 2.23E-42 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 123 203 1.9E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 SUPERFAMILY SSF56784 16 235 1.63E-46 T 12-10-2018 IPR036412 HAD-like superfamily UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 21 208 4.3E-21 T 12-10-2018 UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 Gene3D G3DSA:1.10.150.240 29 109 3.1E-46 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 74 208 2.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 16 27 3.7E-15 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 168 3.7E-15 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 170 190 3.7E-15 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 121 134 3.7E-15 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_25870 a0ed8b65fb730d09a7598e0722d96595 243 Gene3D G3DSA:3.40.50.1000 18 230 3.1E-46 T 12-10-2018 IPR023214 HAD superfamily UA74_23270 1c4e69c760813f52e9c89eab284c467a 150 Pfam PF12728 Helix-turn-helix domain 5 51 2.4E-15 T 12-10-2018 UA74_23270 1c4e69c760813f52e9c89eab284c467a 150 SUPERFAMILY SSF46955 5 51 5.04E-10 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_23270 1c4e69c760813f52e9c89eab284c467a 150 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 51 2.3E-13 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_23270 1c4e69c760813f52e9c89eab284c467a 150 Gene3D G3DSA:1.10.1660.10 2 56 1.4E-14 T 12-10-2018 UA74_01590 9db0a9999a61ecda6fe3a3d429e02f0f 305 Gene3D G3DSA:1.10.1040.20 184 283 2.0E-15 T 12-10-2018 IPR037108 TM1727-like, C-terminal domain superfamily UA74_01590 9db0a9999a61ecda6fe3a3d429e02f0f 305 SUPERFAMILY SSF51735 14 182 8.86E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_01590 9db0a9999a61ecda6fe3a3d429e02f0f 305 SUPERFAMILY SSF48179 185 284 5.78E-24 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_01590 9db0a9999a61ecda6fe3a3d429e02f0f 305 Pfam PF10727 Rossmann-like domain 6 128 6.1E-45 T 12-10-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain UA74_01590 9db0a9999a61ecda6fe3a3d429e02f0f 305 Gene3D G3DSA:3.40.50.720 11 182 4.3E-29 T 12-10-2018 UA74_01590 9db0a9999a61ecda6fe3a3d429e02f0f 305 Pfam PF10728 Domain of unknown function (DUF2520) 160 278 6.1E-36 T 12-10-2018 IPR018931 Domain of unknown function DUF2520 UA74_18625 acf95e9497161760e6b555fc7901aef6 128 Pfam PF01638 HxlR-like helix-turn-helix 1 88 4.7E-24 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_18625 acf95e9497161760e6b555fc7901aef6 128 Gene3D G3DSA:1.10.10.10 1 128 2.7E-41 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18625 acf95e9497161760e6b555fc7901aef6 128 SUPERFAMILY SSF46785 1 126 4.42E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24155 b95922d4b1e8f1ab2636f30a70598821 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 90 1.2E-15 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_24155 b95922d4b1e8f1ab2636f30a70598821 142 SUPERFAMILY SSF50475 2 133 3.93E-26 T 12-10-2018 UA74_24155 b95922d4b1e8f1ab2636f30a70598821 142 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 133 6.2E-35 T 12-10-2018 IPR019920 F420-binding domain, putative UA74_24155 b95922d4b1e8f1ab2636f30a70598821 142 Gene3D G3DSA:2.30.110.10 4 136 1.5E-27 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_25210 3e7d75072aabddab69500d4805d97e1c 329 SUPERFAMILY SSF54001 197 310 1.03E-35 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UA74_25210 3e7d75072aabddab69500d4805d97e1c 329 Pfam PF00877 NlpC/P60 family 215 305 4.7E-20 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UA74_25210 3e7d75072aabddab69500d4805d97e1c 329 Gene3D G3DSA:3.90.1720.10 185 316 1.7E-42 T 12-10-2018 UA74_00020 556e88a78c8b00aad0214f9059683071 385 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 385 92.49 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 UA74_00020 556e88a78c8b00aad0214f9059683071 385 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 367 1.6E-112 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 UA74_00020 556e88a78c8b00aad0214f9059683071 385 Gene3D G3DSA:3.40.50.300 6 359 1.7E-90 T 12-10-2018 UA74_00020 556e88a78c8b00aad0214f9059683071 385 ProSitePatterns PS00618 RecF protein signature 2. 327 345 - T 12-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 UA74_00020 556e88a78c8b00aad0214f9059683071 385 Gene3D G3DSA:1.20.1050.90 120 326 1.7E-90 T 12-10-2018 UA74_00020 556e88a78c8b00aad0214f9059683071 385 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 359 1.1E-14 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal UA74_00020 556e88a78c8b00aad0214f9059683071 385 SUPERFAMILY SSF52540 1 351 7.84E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01615 cc313c8ff210857f900171ec1c670ca1 115 Pfam PF11774 Lsr2 1 114 1.2E-42 T 12-10-2018 IPR024412 Lsr2 UA74_01615 cc313c8ff210857f900171ec1c670ca1 115 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 113 2.0E-27 T 12-10-2018 IPR024412 Lsr2 UA74_01615 cc313c8ff210857f900171ec1c670ca1 115 Gene3D G3DSA:1.20.890.50 81 115 1.2E-17 T 12-10-2018 UA74_01615 cc313c8ff210857f900171ec1c670ca1 115 Gene3D G3DSA:3.30.60.230 1 60 8.1E-26 T 12-10-2018 UA74_18925 5371c0845185af9d1c12ddba1390c773 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 2.3E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_18925 5371c0845185af9d1c12ddba1390c773 132 Gene3D G3DSA:3.10.180.10 1 131 3.0E-40 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_18925 5371c0845185af9d1c12ddba1390c773 132 SUPERFAMILY SSF54593 3 130 9.76E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 Pfam PF16360 GTP-binding GTPase Middle Region 160 244 1.2E-29 T 12-10-2018 IPR032305 GTP-binding protein, middle domain UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 PIRSF PIRSF006809 45 475 5.6E-154 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 252 272 9.2E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 319 337 9.2E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 Gene3D G3DSA:3.40.50.300 249 418 1.4E-36 T 12-10-2018 UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 Hamap MF_00900 GTPase HflX [hflX]. 73 444 47.959 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 Gene3D G3DSA:3.40.50.11060 64 185 2.8E-42 T 12-10-2018 UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 Pfam PF13167 GTP-binding GTPase N-terminal 70 158 1.8E-34 T 12-10-2018 IPR025121 GTPase HflX, N-terminal UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 54 414 8.3E-131 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 Pfam PF01926 50S ribosome-binding GTPase 252 374 1.5E-18 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_08625 85fc3f37cf67bbafd5bf0b84d5b79d3f 477 SUPERFAMILY SSF52540 250 425 1.71E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21430 7042672bb76e41f0bae7098f2c1f4530 429 Pfam PF07730 Histidine kinase 237 306 1.9E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_21430 7042672bb76e41f0bae7098f2c1f4530 429 SMART SM00387 340 429 9.4E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_21430 7042672bb76e41f0bae7098f2c1f4530 429 Gene3D G3DSA:3.30.565.10 309 428 1.3E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_21430 7042672bb76e41f0bae7098f2c1f4530 429 SUPERFAMILY SSF55874 319 427 3.01E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_21430 7042672bb76e41f0bae7098f2c1f4530 429 Pfam PF13796 Putative sensor 35 207 7.3E-9 T 12-10-2018 IPR025828 Putative sensor domain UA74_09680 026189bf2a1b00a84d73def2c743d693 282 SUPERFAMILY SSF88713 33 281 7.26E-94 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UA74_09680 026189bf2a1b00a84d73def2c743d693 282 Gene3D G3DSA:3.20.20.370 32 281 3.2E-97 T 12-10-2018 UA74_09680 026189bf2a1b00a84d73def2c743d693 282 Pfam PF03746 LamB/YcsF family 34 271 8.6E-98 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 UA74_09680 026189bf2a1b00a84d73def2c743d693 282 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 32 276 42.695 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 UA74_19785 65f5f66377f57c2f3ea8cc53a7af1186 453 Gene3D G3DSA:1.20.1250.20 12 192 2.7E-15 T 12-10-2018 UA74_19785 65f5f66377f57c2f3ea8cc53a7af1186 453 Pfam PF07690 Major Facilitator Superfamily 13 193 1.6E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_19785 65f5f66377f57c2f3ea8cc53a7af1186 453 Pfam PF07690 Major Facilitator Superfamily 221 402 2.5E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_19785 65f5f66377f57c2f3ea8cc53a7af1186 453 SUPERFAMILY SSF103473 11 406 1.83E-39 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_19785 65f5f66377f57c2f3ea8cc53a7af1186 453 Gene3D G3DSA:1.20.1250.20 209 401 1.1E-11 T 12-10-2018 UA74_27430 db14d19e5b19ae37d16c69611bc0d408 329 Pfam PF00005 ABC transporter 21 157 2.6E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_27430 db14d19e5b19ae37d16c69611bc0d408 329 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_27430 db14d19e5b19ae37d16c69611bc0d408 329 Gene3D G3DSA:3.40.50.300 6 228 7.2E-59 T 12-10-2018 UA74_27430 db14d19e5b19ae37d16c69611bc0d408 329 SUPERFAMILY SSF52540 8 220 2.05E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_27430 db14d19e5b19ae37d16c69611bc0d408 329 SMART SM00382 30 206 5.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_19540 679ee639168c57fd9e7f3826f2fe98d0 267 Pfam PF09339 IclR helix-turn-helix domain 10 60 2.0E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_19540 679ee639168c57fd9e7f3826f2fe98d0 267 Pfam PF01614 Bacterial transcriptional regulator 132 249 3.0E-30 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_19540 679ee639168c57fd9e7f3826f2fe98d0 267 Gene3D G3DSA:3.30.450.40 82 256 2.7E-44 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_19540 679ee639168c57fd9e7f3826f2fe98d0 267 Gene3D G3DSA:1.10.10.10 1 75 2.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19540 679ee639168c57fd9e7f3826f2fe98d0 267 SUPERFAMILY SSF46785 9 82 2.69E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_19540 679ee639168c57fd9e7f3826f2fe98d0 267 SUPERFAMILY SSF55781 66 254 2.49E-41 T 12-10-2018 UA74_19540 679ee639168c57fd9e7f3826f2fe98d0 267 SMART SM00346 8 98 8.0E-18 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_23865 496dd25cfba806b3bc4bec080f145420 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 1.2E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_23865 496dd25cfba806b3bc4bec080f145420 341 Pfam PF13377 Periplasmic binding protein-like domain 172 334 5.6E-33 T 12-10-2018 UA74_23865 496dd25cfba806b3bc4bec080f145420 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 12-10-2018 UA74_23865 496dd25cfba806b3bc4bec080f145420 341 Gene3D G3DSA:1.10.260.40 2 61 5.8E-19 T 12-10-2018 UA74_23865 496dd25cfba806b3bc4bec080f145420 341 Gene3D G3DSA:3.40.50.2300 162 293 3.9E-74 T 12-10-2018 UA74_23865 496dd25cfba806b3bc4bec080f145420 341 SUPERFAMILY SSF53822 63 337 3.85E-67 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_23865 496dd25cfba806b3bc4bec080f145420 341 SUPERFAMILY SSF47413 5 60 2.53E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_23865 496dd25cfba806b3bc4bec080f145420 341 SMART SM00354 4 74 1.7E-25 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_23865 496dd25cfba806b3bc4bec080f145420 341 Gene3D G3DSA:3.40.50.2300 65 308 3.9E-74 T 12-10-2018 UA74_09430 b71a3449e759537a2d061e344b423350 254 Gene3D G3DSA:1.10.10.10 194 254 1.4E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_09430 b71a3449e759537a2d061e344b423350 254 SMART SM00421 190 247 0.0055 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_09430 b71a3449e759537a2d061e344b423350 254 Pfam PF00196 Bacterial regulatory proteins, luxR family 201 246 4.3E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_09430 b71a3449e759537a2d061e344b423350 254 SUPERFAMILY SSF46894 200 253 2.62E-7 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_00585 bc4201541cea910ce3efbed2c529e0ae 333 Pfam PF00800 Prephenate dehydratase 4 201 2.2E-37 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 UA74_00585 bc4201541cea910ce3efbed2c529e0ae 333 Gene3D G3DSA:3.40.190.10 1 111 5.2E-21 T 12-10-2018 UA74_00585 bc4201541cea910ce3efbed2c529e0ae 333 SUPERFAMILY SSF53850 3 208 8.32E-39 T 12-10-2018 UA74_00585 bc4201541cea910ce3efbed2c529e0ae 333 Gene3D G3DSA:3.40.190.10 112 192 7.2E-23 T 12-10-2018 UA74_00585 bc4201541cea910ce3efbed2c529e0ae 333 SUPERFAMILY SSF55021 202 294 1.07E-23 T 12-10-2018 UA74_00585 bc4201541cea910ce3efbed2c529e0ae 333 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 242 249 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 UA74_00585 bc4201541cea910ce3efbed2c529e0ae 333 Gene3D G3DSA:3.30.70.260 205 298 1.2E-29 T 12-10-2018 UA74_00585 bc4201541cea910ce3efbed2c529e0ae 333 PIRSF PIRSF001500 1 296 1.7E-52 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 UA74_00585 bc4201541cea910ce3efbed2c529e0ae 333 Pfam PF01842 ACT domain 215 280 4.3E-10 T 12-10-2018 IPR002912 ACT domain UA74_22625 e962cef4366b440c4d3579c9a12d997f 319 Gene3D G3DSA:3.40.50.720 28 309 7.4E-108 T 12-10-2018 UA74_22625 e962cef4366b440c4d3579c9a12d997f 319 Gene3D G3DSA:3.40.50.720 105 288 7.4E-108 T 12-10-2018 UA74_22625 e962cef4366b440c4d3579c9a12d997f 319 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 30 316 1.8E-19 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UA74_22625 e962cef4366b440c4d3579c9a12d997f 319 SUPERFAMILY SSF52283 9 140 2.08E-27 T 12-10-2018 UA74_22625 e962cef4366b440c4d3579c9a12d997f 319 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 285 5.1E-48 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_22625 e962cef4366b440c4d3579c9a12d997f 319 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UA74_22625 e962cef4366b440c4d3579c9a12d997f 319 SUPERFAMILY SSF51735 105 286 7.34E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_15820 f70da360a1aae71069c3533ce668a7db 809 Gene3D G3DSA:3.40.50.300 262 466 1.1E-12 T 12-10-2018 UA74_15820 f70da360a1aae71069c3533ce668a7db 809 Gene3D G3DSA:3.40.50.300 467 644 9.5E-11 T 12-10-2018 UA74_15820 f70da360a1aae71069c3533ce668a7db 809 SMART SM00490 531 616 1.5E-4 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_15820 f70da360a1aae71069c3533ce668a7db 809 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 27 234 2.7E-18 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain UA74_15820 f70da360a1aae71069c3533ce668a7db 809 SMART SM00487 259 489 8.4E-6 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_15820 f70da360a1aae71069c3533ce668a7db 809 Gene3D G3DSA:1.10.3210.30 2 261 2.9E-13 T 12-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily UA74_15820 f70da360a1aae71069c3533ce668a7db 809 SUPERFAMILY SSF52540 276 624 1.43E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15820 f70da360a1aae71069c3533ce668a7db 809 SUPERFAMILY SSF109604 30 129 2.63E-6 T 12-10-2018 UA74_15820 f70da360a1aae71069c3533ce668a7db 809 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 276 625 1.2E-58 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 SMART SM01209 119 305 1.1E-111 T 12-10-2018 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 Gene3D G3DSA:3.30.1490.20 121 200 9.9E-12 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 Gene3D G3DSA:3.90.600.10 340 426 2.9E-25 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 Gene3D G3DSA:3.40.50.20 20 111 5.5E-30 T 12-10-2018 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 SUPERFAMILY SSF52440 19 119 2.01E-29 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 341 426 2.5E-25 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 SMART SM01210 340 429 5.1E-35 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 119 305 4.9E-68 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 SUPERFAMILY SSF56059 120 330 1.41E-50 T 12-10-2018 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 299 306 - T 12-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 20 428 1.5E-144 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 20 118 6.1E-28 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 SUPERFAMILY SSF51246 339 428 1.02E-22 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 19 429 38.983 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29355 17103db074e0d3d3f542e4ee3dc1429c 441 Gene3D G3DSA:3.30.470.20 201 337 1.4E-51 T 12-10-2018 UA74_27255 b2695b7303befc72dcbad3f9705466a0 207 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 207 38.938 T 12-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 UA74_27255 b2695b7303befc72dcbad3f9705466a0 207 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 205 2.2E-71 T 12-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 UA74_27255 b2695b7303befc72dcbad3f9705466a0 207 SUPERFAMILY SSF53271 4 205 1.31E-58 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_27255 b2695b7303befc72dcbad3f9705466a0 207 Pfam PF14681 Uracil phosphoribosyltransferase 5 206 5.8E-59 T 12-10-2018 UA74_27255 b2695b7303befc72dcbad3f9705466a0 207 Gene3D G3DSA:3.40.50.2020 1 206 1.0E-68 T 12-10-2018 UA74_23605 4f1ddfdc2c94f0e94ec633e8629ac70d 159 Pfam PF00578 AhpC/TSA family 4 125 5.7E-29 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_23605 4f1ddfdc2c94f0e94ec633e8629ac70d 159 SUPERFAMILY SSF52833 3 149 1.59E-41 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_23605 4f1ddfdc2c94f0e94ec633e8629ac70d 159 Gene3D G3DSA:3.40.30.10 1 151 1.1E-40 T 12-10-2018 UA74_23605 4f1ddfdc2c94f0e94ec633e8629ac70d 159 PIRSF PIRSF000239 1 156 2.1E-18 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 SUPERFAMILY SSF51182 4 398 2.13E-90 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 5 397 1.2E-62 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 Gene3D G3DSA:2.60.120.10 310 404 7.3E-128 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 PIRSF PIRSF001480 1 424 2.1E-93 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 Pfam PF01238 Phosphomannose isomerase type I 4 302 1.1E-56 T 12-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 2.3E-62 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 2.3E-62 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 127 150 2.3E-62 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 2.3E-62 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 2.3E-62 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 2.3E-62 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 82 103 2.3E-62 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 2.3E-62 T 12-10-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 127 135 - T 12-10-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 Gene3D G3DSA:1.10.441.10 151 309 7.3E-128 T 12-10-2018 UA74_26570 a3f95f2de0673e5a8905ae90393c7c70 424 Gene3D G3DSA:2.60.120.10 6 284 7.3E-128 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_27970 590038d2a8110ae5cb4771e616a5aa80 187 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 42 165 8.6E-29 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 UA74_27970 590038d2a8110ae5cb4771e616a5aa80 187 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 45 174 6.1E-22 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 UA74_27970 590038d2a8110ae5cb4771e616a5aa80 187 Gene3D G3DSA:3.40.50.300 34 184 1.1E-31 T 12-10-2018 UA74_27970 590038d2a8110ae5cb4771e616a5aa80 187 SUPERFAMILY SSF52540 57 164 2.19E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29595 a0ce07209e46d79c1cceae1e5f145691 517 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 63 505 3.7E-97 T 12-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 UA74_29595 a0ce07209e46d79c1cceae1e5f145691 517 Pfam PF00939 Sodium:sulfate symporter transmembrane region 36 506 1.7E-90 T 12-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 UA74_29215 2328103dcdcc7ab7efc6c64d0a3eac78 366 SUPERFAMILY SSF56042 176 347 6.28E-55 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UA74_29215 2328103dcdcc7ab7efc6c64d0a3eac78 366 SUPERFAMILY SSF55326 11 173 1.47E-44 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UA74_29215 2328103dcdcc7ab7efc6c64d0a3eac78 366 Gene3D G3DSA:3.30.1330.10 9 174 2.0E-59 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UA74_29215 2328103dcdcc7ab7efc6c64d0a3eac78 366 Pfam PF00586 AIR synthase related protein, N-terminal domain 65 168 1.0E-15 T 12-10-2018 IPR016188 PurM-like, N-terminal domain UA74_29215 2328103dcdcc7ab7efc6c64d0a3eac78 366 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 11 340 1.8E-135 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29215 2328103dcdcc7ab7efc6c64d0a3eac78 366 Pfam PF02769 AIR synthase related protein, C-terminal domain 180 347 1.8E-34 T 12-10-2018 IPR010918 PurM-like, C-terminal domain UA74_29215 2328103dcdcc7ab7efc6c64d0a3eac78 366 Gene3D G3DSA:3.90.650.10 176 355 9.9E-60 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UA74_29215 2328103dcdcc7ab7efc6c64d0a3eac78 366 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 10 357 41.877 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_11500 7e0769df9ae7adbcba9b70178b0a6ae6 311 SUPERFAMILY SSF103481 199 291 3.92E-10 T 12-10-2018 UA74_11500 7e0769df9ae7adbcba9b70178b0a6ae6 311 SUPERFAMILY SSF103481 44 146 7.59E-12 T 12-10-2018 UA74_11500 7e0769df9ae7adbcba9b70178b0a6ae6 311 Pfam PF00892 EamA-like transporter family 154 288 2.2E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_11500 7e0769df9ae7adbcba9b70178b0a6ae6 311 Pfam PF00892 EamA-like transporter family 17 143 2.7E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_27125 efa595f0b1368d387b26df530b126fe5 214 SUPERFAMILY SSF52172 1 176 2.26E-32 T 12-10-2018 IPR011006 CheY-like superfamily UA74_27125 efa595f0b1368d387b26df530b126fe5 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 7.4E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27125 efa595f0b1368d387b26df530b126fe5 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 7.4E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27125 efa595f0b1368d387b26df530b126fe5 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 7.4E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27125 efa595f0b1368d387b26df530b126fe5 214 Gene3D G3DSA:3.40.50.12740 2 213 1.3E-66 T 12-10-2018 UA74_27125 efa595f0b1368d387b26df530b126fe5 214 Pfam PF00072 Response regulator receiver domain 4 114 7.6E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_27125 efa595f0b1368d387b26df530b126fe5 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 8.0E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27125 efa595f0b1368d387b26df530b126fe5 214 SMART SM00448 2 114 4.1E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_27125 efa595f0b1368d387b26df530b126fe5 214 SMART SM00421 150 207 1.9E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17460 3c11c077c664201a8852443839424866 356 Pfam PF13489 Methyltransferase domain 33 189 1.5E-12 T 12-10-2018 UA74_17460 3c11c077c664201a8852443839424866 356 SUPERFAMILY SSF53335 21 204 7.98E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_17460 3c11c077c664201a8852443839424866 356 Gene3D G3DSA:3.40.50.720 258 356 2.8E-38 T 12-10-2018 UA74_17460 3c11c077c664201a8852443839424866 356 Pfam PF08484 C-methyltransferase C-terminal domain 194 351 3.3E-54 T 12-10-2018 IPR013691 C-methyltransferase UA74_17460 3c11c077c664201a8852443839424866 356 Gene3D G3DSA:3.40.50.150 6 206 2.8E-43 T 12-10-2018 UA74_17585 6bf3630254ea6e9cb52791b867b18fbc 535 Pfam PF00221 Aromatic amino acid lyase 17 495 5.2E-163 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 UA74_17585 6bf3630254ea6e9cb52791b867b18fbc 535 SUPERFAMILY SSF48557 8 524 6.67E-169 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 UA74_17585 6bf3630254ea6e9cb52791b867b18fbc 535 Gene3D G3DSA:1.10.275.10 9 203 1.5E-62 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal UA74_17585 6bf3630254ea6e9cb52791b867b18fbc 535 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 145 161 - T 12-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 UA74_17585 6bf3630254ea6e9cb52791b867b18fbc 535 Gene3D G3DSA:1.20.200.10 204 533 1.1E-131 T 12-10-2018 UA74_17585 6bf3630254ea6e9cb52791b867b18fbc 535 TIGRFAM TIGR03832 Tyr_2_3_mutase: tyrosine 2,3-aminomutase 12 518 2.0E-287 T 12-10-2018 IPR022314 Tyrosine 2,3-aminomutase, putative KEGG: 00350+5.4.3.6+4.3.1.23 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Gene3D G3DSA:3.40.50.620 283 419 6.7E-9 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 PRINTS PR00344 Bacterial sensor protein C-terminal signature 851 865 4.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 PRINTS PR00344 Bacterial sensor protein C-terminal signature 869 879 4.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 PRINTS PR00344 Bacterial sensor protein C-terminal signature 884 902 4.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 PRINTS PR00344 Bacterial sensor protein C-terminal signature 908 921 4.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 SUPERFAMILY SSF47384 693 771 1.45E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Gene3D G3DSA:1.20.120.620 440 544 4.0E-16 T 12-10-2018 IPR038318 KdpD, transmembrane domain superfamily UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 813 922 1.1E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 SUPERFAMILY SSF52402 298 419 1.05E-12 T 12-10-2018 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 SMART SM00387 812 924 2.0E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 68 277 1.6E-96 T 12-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Pfam PF00512 His Kinase A (phospho-acceptor) domain 704 770 5.3E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 SUPERFAMILY SSF55874 761 922 3.93E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Gene3D G3DSA:3.30.565.10 781 928 1.1E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 SMART SM00388 703 771 8.7E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Gene3D G3DSA:1.10.287.130 670 769 3.2E-11 T 12-10-2018 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Gene3D G3DSA:3.40.50.300 67 276 1.7E-96 T 12-10-2018 UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Pfam PF13493 Domain of unknown function (DUF4118) 444 549 4.1E-24 T 12-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain UA74_25560 7f33207c59fde060fa6846e66cc1b1a6 929 Pfam PF00582 Universal stress protein family 297 418 1.9E-6 T 12-10-2018 IPR006016 UspA UA74_29790 cccf774c2adfa9db9f4339d84b2df9e3 328 SUPERFAMILY SSF160240 233 305 1.06E-5 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 UA74_29790 cccf774c2adfa9db9f4339d84b2df9e3 328 Pfam PF01545 Cation efflux family 18 227 1.4E-34 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UA74_29790 cccf774c2adfa9db9f4339d84b2df9e3 328 SUPERFAMILY SSF161111 16 229 1.57E-37 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily UA74_29790 cccf774c2adfa9db9f4339d84b2df9e3 328 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 16 308 2.0E-50 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UA74_29790 cccf774c2adfa9db9f4339d84b2df9e3 328 Gene3D G3DSA:1.20.1510.10 15 228 1.9E-33 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily UA74_01320 0114aecde93f7fd096842eafe7cde25f 671 Gene3D G3DSA:3.40.50.12780 69 532 7.4E-103 T 12-10-2018 UA74_01320 0114aecde93f7fd096842eafe7cde25f 671 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 42 95 6.5E-23 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 UA74_01320 0114aecde93f7fd096842eafe7cde25f 671 Gene3D G3DSA:3.30.300.30 535 666 6.8E-31 T 12-10-2018 UA74_01320 0114aecde93f7fd096842eafe7cde25f 671 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 39 661 5.4E-291 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 UA74_01320 0114aecde93f7fd096842eafe7cde25f 671 Pfam PF00501 AMP-binding enzyme 101 539 9.6E-92 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_01320 0114aecde93f7fd096842eafe7cde25f 671 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 23 664 50.558 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 UA74_01320 0114aecde93f7fd096842eafe7cde25f 671 ProSitePatterns PS00455 Putative AMP-binding domain signature. 273 284 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_01320 0114aecde93f7fd096842eafe7cde25f 671 Pfam PF13193 AMP-binding enzyme C-terminal domain 548 630 3.8E-26 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_01320 0114aecde93f7fd096842eafe7cde25f 671 SUPERFAMILY SSF56801 29 659 6.02E-173 T 12-10-2018 UA74_06185 3fdcf5616dbd64c0161892d46d667ca1 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 141 6.1E-12 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_06185 3fdcf5616dbd64c0161892d46d667ca1 351 Gene3D G3DSA:3.90.180.10 7 345 4.6E-110 T 12-10-2018 UA74_06185 3fdcf5616dbd64c0161892d46d667ca1 351 Gene3D G3DSA:3.40.50.720 159 319 4.6E-110 T 12-10-2018 UA74_06185 3fdcf5616dbd64c0161892d46d667ca1 351 SMART SM00829 10 346 6.2E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_06185 3fdcf5616dbd64c0161892d46d667ca1 351 SUPERFAMILY SSF50129 1 179 1.89E-34 T 12-10-2018 IPR011032 GroES-like superfamily UA74_06185 3fdcf5616dbd64c0161892d46d667ca1 351 SUPERFAMILY SSF51735 150 323 3.51E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_06185 3fdcf5616dbd64c0161892d46d667ca1 351 Pfam PF00107 Zinc-binding dehydrogenase 183 307 1.9E-27 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_19645 590323ee2ee7916e57deb0e0b056e4c0 417 SUPERFAMILY SSF103473 31 410 5.36E-36 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_19645 590323ee2ee7916e57deb0e0b056e4c0 417 Pfam PF07690 Major Facilitator Superfamily 34 369 8.3E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_19645 590323ee2ee7916e57deb0e0b056e4c0 417 Gene3D G3DSA:1.20.1250.20 24 407 7.2E-31 T 12-10-2018 UA74_01445 26fb44a75446395d37650e925d742d17 954 SMART SM00436 165 253 1.7E-43 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 361 375 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 UA74_01445 26fb44a75446395d37650e925d742d17 954 Gene3D G3DSA:1.10.460.10 196 634 7.9E-173 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 UA74_01445 26fb44a75446395d37650e925d742d17 954 SUPERFAMILY SSF56712 51 635 1.05E-175 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain UA74_01445 26fb44a75446395d37650e925d742d17 954 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 53 699 1.8E-247 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 Pfam PF01751 Toprim domain 53 174 1.9E-28 T 12-10-2018 IPR006171 TOPRIM domain UA74_01445 26fb44a75446395d37650e925d742d17 954 Hamap MF_00952 DNA topoisomerase 1 [topA]. 51 825 55.248 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 Gene3D G3DSA:1.10.290.10 332 460 7.9E-173 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 UA74_01445 26fb44a75446395d37650e925d742d17 954 SMART SM00437 324 594 3.1E-124 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 Pfam PF13368 Topoisomerase C-terminal repeat 742 799 1.6E-13 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat UA74_01445 26fb44a75446395d37650e925d742d17 954 Pfam PF13368 Topoisomerase C-terminal repeat 872 925 6.5E-21 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat UA74_01445 26fb44a75446395d37650e925d742d17 954 Pfam PF13368 Topoisomerase C-terminal repeat 804 857 4.5E-17 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat UA74_01445 26fb44a75446395d37650e925d742d17 954 Pfam PF13368 Topoisomerase C-terminal repeat 678 735 1.6E-7 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat UA74_01445 26fb44a75446395d37650e925d742d17 954 SMART SM00493 51 165 2.2E-39 T 12-10-2018 IPR006171 TOPRIM domain UA74_01445 26fb44a75446395d37650e925d742d17 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 223 241 4.4E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 366 375 4.4E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 557 571 4.4E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 139 152 4.4E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 445 461 4.4E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 Gene3D G3DSA:3.40.50.140 50 195 2.4E-57 T 12-10-2018 UA74_01445 26fb44a75446395d37650e925d742d17 954 Pfam PF01131 DNA topoisomerase 189 631 5.7E-119 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UA74_01445 26fb44a75446395d37650e925d742d17 954 Gene3D G3DSA:2.70.20.10 245 541 7.9E-173 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 UA74_06895 4637ec10b72d314b11d5162dd79ee191 88 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 85 19.392 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 UA74_06895 4637ec10b72d314b11d5162dd79ee191 88 Pfam PF02416 mttA/Hcf106 family 4 52 2.7E-14 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 UA74_14480 3532422950c22b65023760409ef8472e 547 Gene3D G3DSA:3.40.50.300 313 546 4.7E-41 T 12-10-2018 UA74_14480 3532422950c22b65023760409ef8472e 547 SUPERFAMILY SSF52540 361 543 4.28E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14480 3532422950c22b65023760409ef8472e 547 Pfam PF00005 ABC transporter 367 495 8.4E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_14480 3532422950c22b65023760409ef8472e 547 SMART SM00382 29 232 2.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_14480 3532422950c22b65023760409ef8472e 547 SMART SM00382 374 541 3.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_14480 3532422950c22b65023760409ef8472e 547 Gene3D G3DSA:3.40.50.300 11 291 3.7E-51 T 12-10-2018 UA74_14480 3532422950c22b65023760409ef8472e 547 SUPERFAMILY SSF52540 5 229 5.14E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14480 3532422950c22b65023760409ef8472e 547 Pfam PF00005 ABC transporter 22 187 1.1E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13025 0f5b5d0028f7be74ff412ad1a726dee0 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 191 5.2E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_13025 0f5b5d0028f7be74ff412ad1a726dee0 201 Gene3D G3DSA:1.10.10.10 130 199 2.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13025 0f5b5d0028f7be74ff412ad1a726dee0 201 Pfam PF08281 Sigma-70, region 4 137 188 6.2E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_13025 0f5b5d0028f7be74ff412ad1a726dee0 201 Pfam PF04542 Sigma-70 region 2 39 104 2.3E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_13025 0f5b5d0028f7be74ff412ad1a726dee0 201 SUPERFAMILY SSF88946 19 115 3.92E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_13025 0f5b5d0028f7be74ff412ad1a726dee0 201 SUPERFAMILY SSF88659 133 193 6.76E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_13025 0f5b5d0028f7be74ff412ad1a726dee0 201 Gene3D G3DSA:1.10.1740.10 13 100 1.0E-28 T 12-10-2018 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 SUPERFAMILY SSF51230 1 96 2.75E-27 T 12-10-2018 IPR011053 Single hybrid motif UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 153 182 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 Pfam PF02817 e3 binding domain 273 307 8.1E-15 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 Gene3D G3DSA:2.40.50.100 2 102 5.7E-27 T 12-10-2018 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 Gene3D G3DSA:2.40.50.100 124 226 1.8E-26 T 12-10-2018 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 SUPERFAMILY SSF52777 334 570 1.11E-78 T 12-10-2018 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 Gene3D G3DSA:4.10.320.10 274 315 4.7E-16 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 SUPERFAMILY SSF47005 266 311 2.62E-12 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 579 3.0E-262 T 12-10-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 Pfam PF00364 Biotin-requiring enzyme 5 76 1.5E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 Pfam PF00364 Biotin-requiring enzyme 130 201 5.5E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 343 570 9.6E-76 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 SUPERFAMILY SSF51230 130 222 1.01E-26 T 12-10-2018 IPR011053 Single hybrid motif UA74_25070 15d5326c9a3bd5aa56afeb19975e92a0 579 Gene3D G3DSA:3.30.559.10 323 576 5.8E-84 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 79 2.3E-27 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 ProSitePatterns PS00057 Ribosomal protein S18 signature. 28 51 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 6.2E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 6.2E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 6.2E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 6.2E-16 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 Pfam PF01084 Ribosomal protein S18 26 75 3.0E-23 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 80 20.045 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 79 5.0E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 SUPERFAMILY SSF46911 5 79 2.49E-24 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30015 bee95d21e95e9924b7900939b36f5035 82 Gene3D G3DSA:4.10.640.10 1 82 3.7E-27 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21820 a785f4a8d0ae0aaee262d73c0e299d1e 219 Gene3D G3DSA:1.10.10.10 126 219 9.0E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21820 a785f4a8d0ae0aaee262d73c0e299d1e 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 218 9.2E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_21820 a785f4a8d0ae0aaee262d73c0e299d1e 219 SMART SM00448 2 113 9.1E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_21820 a785f4a8d0ae0aaee262d73c0e299d1e 219 SMART SM00862 147 218 2.6E-30 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_21820 a785f4a8d0ae0aaee262d73c0e299d1e 219 SUPERFAMILY SSF52172 1 176 3.15E-36 T 12-10-2018 IPR011006 CheY-like superfamily UA74_21820 a785f4a8d0ae0aaee262d73c0e299d1e 219 Pfam PF00072 Response regulator receiver domain 4 114 1.2E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_21820 a785f4a8d0ae0aaee262d73c0e299d1e 219 Gene3D G3DSA:3.40.50.2300 1 121 6.0E-36 T 12-10-2018 UA74_26300 008b3917237355c7b1faf88fba8a03f9 386 Gene3D G3DSA:3.20.20.140 60 345 2.2E-121 T 12-10-2018 UA74_26300 008b3917237355c7b1faf88fba8a03f9 386 SUPERFAMILY SSF51338 11 73 2.7E-9 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_26300 008b3917237355c7b1faf88fba8a03f9 386 SUPERFAMILY SSF51338 321 385 4.37E-13 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_26300 008b3917237355c7b1faf88fba8a03f9 386 Pfam PF01979 Amidohydrolase family 57 366 7.4E-15 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_26300 008b3917237355c7b1faf88fba8a03f9 386 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 385 41.314 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26300 008b3917237355c7b1faf88fba8a03f9 386 SUPERFAMILY SSF51556 59 338 2.94E-68 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_26300 008b3917237355c7b1faf88fba8a03f9 386 Gene3D G3DSA:2.30.40.10 15 383 2.2E-121 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_26300 008b3917237355c7b1faf88fba8a03f9 386 TIGRFAM TIGR01224 hutI: imidazolonepropionase 24 383 5.0E-101 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 Gene3D G3DSA:3.30.70.920 55 138 2.7E-13 T 12-10-2018 UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.9E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.9E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.9E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 Pfam PF01037 Lrp/AsnC ligand binding domain 84 125 1.3E-7 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 3.4E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 SUPERFAMILY SSF54909 65 138 2.55E-10 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 SMART SM00344 3 110 2.2E-22 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 Gene3D G3DSA:1.10.10.10 1 54 8.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28890 9b8878c46990d77b2a40353b1a31fba7 164 SUPERFAMILY SSF46785 2 62 3.89E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 SMART SM00052 443 693 8.9E-22 T 12-10-2018 IPR001633 EAL domain UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 SMART SM00267 261 433 3.8E-27 T 12-10-2018 IPR000160 GGDEF domain UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 142 267 2.2E-22 T 12-10-2018 IPR000014 PAS domain UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 Gene3D G3DSA:3.30.70.270 267 446 1.7E-35 T 12-10-2018 UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 270 430 1.3E-24 T 12-10-2018 IPR000160 GGDEF domain UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 SMART SM00086 219 261 9.7E-5 T 12-10-2018 IPR001610 PAC motif UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 SUPERFAMILY SSF55785 135 259 1.29E-23 T 12-10-2018 IPR035965 PAS domain superfamily UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 Pfam PF00990 Diguanylate cyclase, GGDEF domain 273 427 2.9E-27 T 12-10-2018 IPR000160 GGDEF domain UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 SMART SM00091 146 212 1.9E-11 T 12-10-2018 IPR000014 PAS domain UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 Pfam PF00563 EAL domain 452 685 3.5E-42 T 12-10-2018 IPR001633 EAL domain UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 Gene3D G3DSA:3.20.20.450 447 702 1.1E-51 T 12-10-2018 IPR035919 EAL domain superfamily UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 SUPERFAMILY SSF141868 452 700 2.75E-40 T 12-10-2018 IPR035919 EAL domain superfamily UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 Gene3D G3DSA:3.30.450.20 132 259 6.0E-23 T 12-10-2018 UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 SUPERFAMILY SSF55073 277 435 7.14E-30 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_06135 cd9dfd231a62bb0df6b55aafaf744452 704 Pfam PF13426 PAS domain 158 260 1.0E-10 T 12-10-2018 IPR000014 PAS domain UA74_07565 78a56e27a6c6d9b45831bbcc660b6b35 231 Pfam PF07110 EthD domain 12 93 5.8E-10 T 12-10-2018 IPR009799 EthD domain UA74_07565 78a56e27a6c6d9b45831bbcc660b6b35 231 SUPERFAMILY SSF54909 122 225 1.53E-26 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_07565 78a56e27a6c6d9b45831bbcc660b6b35 231 SUPERFAMILY SSF54909 2 103 4.69E-19 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_07565 78a56e27a6c6d9b45831bbcc660b6b35 231 Gene3D G3DSA:3.30.70.100 1 89 1.5E-8 T 12-10-2018 UA74_07565 78a56e27a6c6d9b45831bbcc660b6b35 231 Gene3D G3DSA:3.30.70.100 121 216 4.0E-15 T 12-10-2018 UA74_07565 78a56e27a6c6d9b45831bbcc660b6b35 231 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 131 214 4.6E-13 T 12-10-2018 IPR009799 EthD domain UA74_07565 78a56e27a6c6d9b45831bbcc660b6b35 231 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 4 82 3.4E-8 T 12-10-2018 IPR009799 EthD domain UA74_07565 78a56e27a6c6d9b45831bbcc660b6b35 231 Pfam PF09448 Methylmuconolactone methyl-isomerase 123 227 1.1E-12 T 12-10-2018 IPR018566 4-Methylmuconolactone methyl-isomerase UA74_07885 82d3d4242e7a0e7846a4012f1d3b0f1a 531 SUPERFAMILY SSF51445 16 468 6.04E-121 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07885 82d3d4242e7a0e7846a4012f1d3b0f1a 531 Gene3D G3DSA:3.90.400.10 117 189 1.8E-156 T 12-10-2018 UA74_07885 82d3d4242e7a0e7846a4012f1d3b0f1a 531 Pfam PF11941 Domain of unknown function (DUF3459) 454 530 1.4E-7 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) UA74_07885 82d3d4242e7a0e7846a4012f1d3b0f1a 531 SMART SM00642 25 408 1.1E-110 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07885 82d3d4242e7a0e7846a4012f1d3b0f1a 531 Pfam PF00128 Alpha amylase, catalytic domain 40 383 4.5E-78 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07885 82d3d4242e7a0e7846a4012f1d3b0f1a 531 Gene3D G3DSA:3.20.20.80 17 463 1.8E-156 T 12-10-2018 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00823 Phosphopantetheine attachment site 1653 1724 5.6E-18 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 262 379 4.1E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.40.366.10 527 825 1.8E-128 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.10.129.110 877 1149 2.5E-30 T 12-10-2018 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.40.50.720 1150 1632 1.5E-102 T 12-10-2018 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00825 Beta-ketoacyl synthase 7 432 2.9E-200 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF00698 Acyl transferase domain 527 833 3.7E-81 T 12-10-2018 IPR014043 Acyl transferase UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF52151 526 809 2.43E-60 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF00550 Phosphopantetheine attachment site 1655 1720 2.0E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF53901 2 375 4.01E-100 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM01294 1654 1720 3.6E-5 T 12-10-2018 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF08659 KR domain 1366 1557 2.1E-59 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:1.10.1200.10 1642 1727 1.6E-18 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF51735 1156 1350 2.51E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.40.47.10 1 444 1.6E-183 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF51735 1364 1572 2.13E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF14765 Polyketide synthase dehydratase 886 1150 9.1E-18 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1679 1694 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 382 494 6.7E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 254 4.4E-83 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 167 183 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 Gene3D G3DSA:3.30.70.3290 446 868 1.8E-128 T 12-10-2018 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 529 822 1.2E-86 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF55048 648 708 2.09E-7 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1366 1559 1.4E-53 T 12-10-2018 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SMART SM00826 886 1037 6.9E-5 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17515 f3a6608294fc2a1598bdbacdf5822634 1735 SUPERFAMILY SSF47336 1652 1726 4.06E-15 T 12-10-2018 IPR036736 ACP-like superfamily UA74_24435 56fb919cb8e90cd246cd22270a7fd434 310 SMART SM00382 28 205 7.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_24435 56fb919cb8e90cd246cd22270a7fd434 310 SUPERFAMILY SSF52540 3 234 2.62E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24435 56fb919cb8e90cd246cd22270a7fd434 310 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_24435 56fb919cb8e90cd246cd22270a7fd434 310 Gene3D G3DSA:3.40.50.300 1 229 1.0E-64 T 12-10-2018 UA74_24435 56fb919cb8e90cd246cd22270a7fd434 310 Pfam PF00005 ABC transporter 20 157 7.7E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 Gene3D G3DSA:1.10.10.10 3 88 4.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 SUPERFAMILY SSF53850 91 291 3.72E-31 T 12-10-2018 UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 Pfam PF03466 LysR substrate binding domain 88 290 3.7E-34 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.0E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 Gene3D G3DSA:3.40.190.10 92 281 1.0E-34 T 12-10-2018 UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 SUPERFAMILY SSF46785 2 112 1.59E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_15365 7daeb9179592814031da0ae3d5031ce1 310 Gene3D G3DSA:3.40.190.10 165 266 1.0E-34 T 12-10-2018 UA74_13460 a0be26de18822621289970bba1046d7e 140 Pfam PF04075 F420H(2)-dependent quinone reductase 10 133 8.6E-38 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_13460 a0be26de18822621289970bba1046d7e 140 Gene3D G3DSA:2.30.110.10 1 134 1.3E-49 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_13460 a0be26de18822621289970bba1046d7e 140 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 21 132 1.1E-28 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_13460 a0be26de18822621289970bba1046d7e 140 SUPERFAMILY SSF50475 24 118 7.66E-8 T 12-10-2018 UA74_30295 541eae0042cbecdbe8a930e224fc115b 309 Gene3D G3DSA:3.40.50.300 2 309 1.7E-91 T 12-10-2018 UA74_30295 541eae0042cbecdbe8a930e224fc115b 309 SUPERFAMILY SSF52540 7 307 4.21E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_30295 541eae0042cbecdbe8a930e224fc115b 309 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 89 224 1.6E-10 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 UA74_30295 541eae0042cbecdbe8a930e224fc115b 309 PIRSF PIRSF000545 1 309 6.4E-137 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_30295 541eae0042cbecdbe8a930e224fc115b 309 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 10 308 1.7E-123 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_30295 541eae0042cbecdbe8a930e224fc115b 309 Hamap MF_00215 Pantothenate kinase [coaA]. 1 309 166.808 T 12-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 Gene3D G3DSA:2.60.40.10 742 854 4.5E-30 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 Pfam PF14310 Fibronectin type III-like domain 772 841 8.6E-19 T 12-10-2018 IPR026891 Fibronectin type III-like domain UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 SUPERFAMILY SSF51445 69 471 3.72E-96 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 Gene3D G3DSA:3.20.20.300 78 433 3.2E-104 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 PRINTS PR00133 Glycosyl hydrolase family 3 signature 267 283 4.9E-20 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 PRINTS PR00133 Glycosyl hydrolase family 3 signature 236 252 4.9E-20 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 PRINTS PR00133 Glycosyl hydrolase family 3 signature 338 356 4.9E-20 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 PRINTS PR00133 Glycosyl hydrolase family 3 signature 167 183 4.9E-20 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 PRINTS PR00133 Glycosyl hydrolase family 3 signature 190 209 4.9E-20 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 472 709 4.1E-46 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 Gene3D G3DSA:3.40.50.1700 457 710 1.2E-62 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 90 418 1.3E-70 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 SUPERFAMILY SSF52279 472 712 4.84E-47 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 UA74_18875 9bd4a85537333d03db7f78e2ea9ecbb1 880 SMART SM01217 772 841 8.7E-27 T 12-10-2018 IPR026891 Fibronectin type III-like domain UA74_26160 df343af2434d73a86cae344bc4e0f170 385 Gene3D G3DSA:1.10.540.10 1 120 3.8E-38 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_26160 df343af2434d73a86cae344bc4e0f170 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_26160 df343af2434d73a86cae344bc4e0f170 385 SUPERFAMILY SSF56645 2 246 7.33E-77 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_26160 df343af2434d73a86cae344bc4e0f170 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 4.9E-34 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UA74_26160 df343af2434d73a86cae344bc4e0f170 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 221 1.7E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UA74_26160 df343af2434d73a86cae344bc4e0f170 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 2.2E-48 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_26160 df343af2434d73a86cae344bc4e0f170 385 SUPERFAMILY SSF47203 231 381 1.61E-50 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_26160 df343af2434d73a86cae344bc4e0f170 385 Gene3D G3DSA:1.20.140.10 240 385 1.0E-49 T 12-10-2018 UA74_26160 df343af2434d73a86cae344bc4e0f170 385 Gene3D G3DSA:2.40.110.10 122 239 1.3E-35 T 12-10-2018 UA74_26160 df343af2434d73a86cae344bc4e0f170 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_01270 3998517bfaec1edeac5ab013664fb136 249 Pfam PF00293 NUDIX domain 54 174 1.4E-11 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_01270 3998517bfaec1edeac5ab013664fb136 249 SUPERFAMILY SSF55811 55 209 3.25E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_01270 3998517bfaec1edeac5ab013664fb136 249 Gene3D G3DSA:3.90.79.10 42 216 7.6E-33 T 12-10-2018 UA74_00790 d18b7dac534b1f4530fe899610ac0925 397 SUPERFAMILY SSF53474 129 328 2.34E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_00790 d18b7dac534b1f4530fe899610ac0925 397 Pfam PF12740 Chlorophyllase enzyme 129 271 4.4E-7 T 12-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 UA74_00790 d18b7dac534b1f4530fe899610ac0925 397 Gene3D G3DSA:3.40.50.1820 32 382 1.9E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_03335 9a70faf47f362d798255338a53ad04f7 306 SUPERFAMILY SSF46785 1 82 9.25E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_03335 9a70faf47f362d798255338a53ad04f7 306 SUPERFAMILY SSF53850 88 281 6.04E-38 T 12-10-2018 UA74_03335 9a70faf47f362d798255338a53ad04f7 306 Gene3D G3DSA:1.10.10.10 1 83 2.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_03335 9a70faf47f362d798255338a53ad04f7 306 Pfam PF03466 LysR substrate binding domain 88 281 1.9E-41 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_03335 9a70faf47f362d798255338a53ad04f7 306 Gene3D G3DSA:3.40.190.290 91 294 4.0E-43 T 12-10-2018 UA74_03335 9a70faf47f362d798255338a53ad04f7 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_03335 9a70faf47f362d798255338a53ad04f7 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_03335 9a70faf47f362d798255338a53ad04f7 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_03335 9a70faf47f362d798255338a53ad04f7 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.9E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_28295 896d1961d45ea12daca81e3c7e8ffde2 621 Pfam PF00005 ABC transporter 397 546 6.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_28295 896d1961d45ea12daca81e3c7e8ffde2 621 SMART SM00382 406 592 1.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28295 896d1961d45ea12daca81e3c7e8ffde2 621 SUPERFAMILY SSF90123 48 367 1.23E-68 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_28295 896d1961d45ea12daca81e3c7e8ffde2 621 Pfam PF00664 ABC transporter transmembrane region 61 328 1.2E-39 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_28295 896d1961d45ea12daca81e3c7e8ffde2 621 SUPERFAMILY SSF52540 371 615 3.03E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28295 896d1961d45ea12daca81e3c7e8ffde2 621 Gene3D G3DSA:1.20.1560.10 29 367 6.6E-73 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_28295 896d1961d45ea12daca81e3c7e8ffde2 621 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_28295 896d1961d45ea12daca81e3c7e8ffde2 621 Gene3D G3DSA:3.40.50.300 371 619 4.2E-84 T 12-10-2018 UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 1.9E-68 T 12-10-2018 UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 1.6E-4 T 12-10-2018 UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 Gene3D G3DSA:3.40.50.720 1 252 1.8E-84 T 12-10-2018 UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.8E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.8E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.8E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 SUPERFAMILY SSF51735 7 250 1.26E-83 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.6E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.6E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.6E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13545 e5a9fab0c7a7ae883b26db7f40d23461 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18230 65d6788d9a50e89a49ab506bf7b81a72 820 Gene3D G3DSA:2.60.40.1180 344 817 8.3E-253 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_18230 65d6788d9a50e89a49ab506bf7b81a72 820 Gene3D G3DSA:1.50.10.10 70 766 8.3E-253 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_18230 65d6788d9a50e89a49ab506bf7b81a72 820 PIRSF PIRSF007663 38 797 1.1E-243 T 12-10-2018 IPR016518 Alpha-L-fucosidase GO:0004560 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 UA74_18230 65d6788d9a50e89a49ab506bf7b81a72 820 Gene3D G3DSA:2.70.98.50 75 343 8.3E-253 T 12-10-2018 UA74_18230 65d6788d9a50e89a49ab506bf7b81a72 820 SUPERFAMILY SSF48208 309 759 3.91E-84 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_18230 65d6788d9a50e89a49ab506bf7b81a72 820 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 61 299 1.9E-68 T 12-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 UA74_23295 e9587b248a3185f8cd7155e99e630c9f 655 SUPERFAMILY SSF52540 374 590 5.43E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_23295 e9587b248a3185f8cd7155e99e630c9f 655 Pfam PF00005 ABC transporter 393 542 6.8E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_23295 e9587b248a3185f8cd7155e99e630c9f 655 ProSitePatterns PS00211 ABC transporters family signature. 514 528 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_23295 e9587b248a3185f8cd7155e99e630c9f 655 Pfam PF00664 ABC transporter transmembrane region 81 245 1.0E-15 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_23295 e9587b248a3185f8cd7155e99e630c9f 655 Gene3D G3DSA:1.20.1560.10 5 291 9.1E-28 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_23295 e9587b248a3185f8cd7155e99e630c9f 655 Gene3D G3DSA:3.40.50.300 361 602 1.0E-74 T 12-10-2018 UA74_23295 e9587b248a3185f8cd7155e99e630c9f 655 SUPERFAMILY SSF90123 11 282 1.06E-34 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_23295 e9587b248a3185f8cd7155e99e630c9f 655 SMART SM00382 402 588 1.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_00545 e775ace5dac2d792ad20039ac91a5a23 233 Gene3D G3DSA:1.10.10.10 26 99 3.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_00545 e775ace5dac2d792ad20039ac91a5a23 233 SUPERFAMILY SSF55781 88 232 2.94E-16 T 12-10-2018 UA74_00545 e775ace5dac2d792ad20039ac91a5a23 233 SUPERFAMILY SSF46785 32 101 6.15E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_00545 e775ace5dac2d792ad20039ac91a5a23 233 SMART SM00346 30 117 1.8E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_00545 e775ace5dac2d792ad20039ac91a5a23 233 Pfam PF09339 IclR helix-turn-helix domain 32 84 8.2E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_00545 e775ace5dac2d792ad20039ac91a5a23 233 Gene3D G3DSA:3.30.450.40 102 177 1.4E-8 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 Gene3D G3DSA:1.10.630.10 23 416 5.7E-123 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 Pfam PF00067 Cytochrome P450 285 386 1.9E-19 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00385 P450 superfamily signature 254 271 1.7E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00385 P450 superfamily signature 289 300 1.7E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00385 P450 superfamily signature 356 365 1.7E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00385 P450 superfamily signature 365 376 1.7E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 SUPERFAMILY SSF48264 29 416 8.91E-96 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 358 367 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00359 B-class P450 signature 212 234 1.9E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00359 B-class P450 signature 307 334 1.9E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00359 B-class P450 signature 335 350 1.9E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00359 B-class P450 signature 289 300 1.9E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00359 B-class P450 signature 356 365 1.9E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00359 B-class P450 signature 158 174 1.9E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00359 B-class P450 signature 111 122 1.9E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00359 B-class P450 signature 175 190 1.9E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12250 c19e7fd7b84411283a4647b02454cd33 416 PRINTS PR00359 B-class P450 signature 365 376 1.9E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20370 96331840d07ac3d789b2ebee7ad488ec 816 Gene3D G3DSA:2.60.420.10 717 783 1.3E-10 T 12-10-2018 UA74_20370 96331840d07ac3d789b2ebee7ad488ec 816 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 9 263 4.7E-69 T 12-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 UA74_20370 96331840d07ac3d789b2ebee7ad488ec 816 Gene3D G3DSA:1.50.10.10 311 716 3.2E-145 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_20370 96331840d07ac3d789b2ebee7ad488ec 816 SUPERFAMILY SSF74650 3 264 1.38E-66 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 UA74_20370 96331840d07ac3d789b2ebee7ad488ec 816 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 318 731 5.2E-137 T 12-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 UA74_20370 96331840d07ac3d789b2ebee7ad488ec 816 SUPERFAMILY SSF48208 270 772 3.32E-102 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_20370 96331840d07ac3d789b2ebee7ad488ec 816 Gene3D G3DSA:2.70.98.40 1 265 1.8E-76 T 12-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily UA74_20370 96331840d07ac3d789b2ebee7ad488ec 816 PIRSF PIRSF036289 1 799 1.6E-201 T 12-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase UA74_05750 33d299909d953640d4bfb17368302ffc 300 Gene3D G3DSA:3.40.366.10 3 276 3.4E-78 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_05750 33d299909d953640d4bfb17368302ffc 300 Gene3D G3DSA:3.30.70.250 122 190 3.4E-78 T 12-10-2018 UA74_05750 33d299909d953640d4bfb17368302ffc 300 PIRSF PIRSF000446 1 296 2.4E-62 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 UA74_05750 33d299909d953640d4bfb17368302ffc 300 Pfam PF00698 Acyl transferase domain 4 266 1.1E-39 T 12-10-2018 IPR014043 Acyl transferase UA74_05750 33d299909d953640d4bfb17368302ffc 300 SUPERFAMILY SSF52151 1 280 9.16E-58 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_05750 33d299909d953640d4bfb17368302ffc 300 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 294 2.8E-20 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_05750 33d299909d953640d4bfb17368302ffc 300 SUPERFAMILY SSF55048 124 190 1.57E-8 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_05520 0b947d1cc2d14761d39e2418d897c528 415 Pfam PF07690 Major Facilitator Superfamily 29 351 1.5E-31 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_05520 0b947d1cc2d14761d39e2418d897c528 415 SUPERFAMILY SSF103473 14 403 5.75E-53 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_05520 0b947d1cc2d14761d39e2418d897c528 415 Gene3D G3DSA:1.20.1250.20 16 409 5.6E-42 T 12-10-2018 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 Pfam PF00289 Biotin carboxylase, N-terminal domain 21 129 2.8E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 305 312 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 SUPERFAMILY SSF51230 532 601 9.29E-19 T 12-10-2018 IPR011053 Single hybrid motif UA74_26940 aaceef35d972d3c019c45495d6e25076 603 SUPERFAMILY SSF51246 348 467 7.85E-37 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 Gene3D G3DSA:3.30.470.130 9 468 1.0E-176 T 12-10-2018 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 Pfam PF02785 Biotin carboxylase C-terminal domain 354 463 6.9E-36 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 SUPERFAMILY SSF56059 102 342 1.33E-58 T 12-10-2018 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 SUPERFAMILY SSF52440 18 132 8.63E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_26940 aaceef35d972d3c019c45495d6e25076 603 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 558 575 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 134 341 6.3E-76 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 SMART SM00878 354 463 4.1E-57 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 Gene3D G3DSA:2.40.50.100 526 602 1.2E-19 T 12-10-2018 UA74_26940 aaceef35d972d3c019c45495d6e25076 603 Pfam PF00364 Biotin-requiring enzyme 536 601 3.0E-16 T 12-10-2018 IPR000089 Biotin/lipoyl attachment UA74_25965 b5f0ce0790d6c6f8e8d3bc2950437cb7 287 Gene3D G3DSA:1.10.260.40 9 76 4.3E-9 T 12-10-2018 UA74_25965 b5f0ce0790d6c6f8e8d3bc2950437cb7 287 SMART SM00530 16 71 2.6E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_25965 b5f0ce0790d6c6f8e8d3bc2950437cb7 287 Pfam PF13560 Helix-turn-helix domain 12 74 3.4E-11 T 12-10-2018 UA74_25965 b5f0ce0790d6c6f8e8d3bc2950437cb7 287 SUPERFAMILY SSF47413 10 71 2.76E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 Pfam PF00394 Multicopper oxidase 254 347 4.1E-5 T 12-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 Gene3D G3DSA:2.60.40.420 50 130 4.5E-17 T 12-10-2018 IPR008972 Cupredoxin UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 Gene3D G3DSA:2.60.40.420 131 213 1.7E-23 T 12-10-2018 IPR008972 Cupredoxin UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 SUPERFAMILY SSF49503 414 524 5.94E-24 T 12-10-2018 IPR008972 Cupredoxin UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 Pfam PF07731 Multicopper oxidase 416 524 1.3E-22 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 Gene3D G3DSA:2.60.40.420 387 525 1.8E-40 T 12-10-2018 IPR008972 Cupredoxin UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 SUPERFAMILY SSF49503 220 346 2.13E-23 T 12-10-2018 IPR008972 Cupredoxin UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 Gene3D G3DSA:2.60.40.420 214 386 4.7E-51 T 12-10-2018 IPR008972 Cupredoxin UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 Pfam PF07732 Multicopper oxidase 90 216 1.2E-16 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_22405 c13551c50e3e1ed9a564cd38597d7005 525 SUPERFAMILY SSF49503 57 217 4.58E-26 T 12-10-2018 IPR008972 Cupredoxin UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 SUPERFAMILY SSF51445 133 576 3.58E-135 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 Gene3D G3DSA:2.60.40.10 1 136 1.9E-45 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 6.5E-18 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 680 0.0 T 12-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 Pfam PF00128 Alpha amylase, catalytic domain 188 277 3.0E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 Pfam PF00128 Alpha amylase, catalytic domain 311 454 2.7E-4 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 SUPERFAMILY SSF51011 590 716 1.58E-23 T 12-10-2018 UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 SUPERFAMILY SSF81296 5 147 2.8E-44 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 Gene3D G3DSA:3.20.20.80 138 582 1.5E-180 T 12-10-2018 UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 SMART SM00642 158 568 1.1E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_21235 588fa91430324ca51a2afdd22e6b7300 722 Gene3D G3DSA:2.60.40.1180 589 715 2.5E-16 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_28240 19aa013b85d65851cdf22779aeb7fc60 395 Gene3D G3DSA:2.30.40.10 1 372 1.3E-125 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_28240 19aa013b85d65851cdf22779aeb7fc60 395 Pfam PF01979 Amidohydrolase family 46 372 1.5E-14 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_28240 19aa013b85d65851cdf22779aeb7fc60 395 SUPERFAMILY SSF51556 48 342 5.88E-46 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_28240 19aa013b85d65851cdf22779aeb7fc60 395 SUPERFAMILY SSF51338 4 377 8.82E-19 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_28240 19aa013b85d65851cdf22779aeb7fc60 395 Gene3D G3DSA:3.20.20.140 49 338 1.3E-125 T 12-10-2018 UA74_06025 4e5539e511d7ae415f1c348123900a66 294 Pfam PF02517 CAAX protease self-immunity 182 281 7.2E-15 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 UA74_16535 3038902a4915b121e2f2d9b52ebf4a2b 315 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 306 3.6E-96 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_16535 3038902a4915b121e2f2d9b52ebf4a2b 315 Gene3D G3DSA:3.40.50.300 1 265 7.1E-66 T 12-10-2018 UA74_16535 3038902a4915b121e2f2d9b52ebf4a2b 315 SMART SM00382 30 221 9.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_16535 3038902a4915b121e2f2d9b52ebf4a2b 315 Pfam PF00005 ABC transporter 21 164 2.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_16535 3038902a4915b121e2f2d9b52ebf4a2b 315 SUPERFAMILY SSF52540 3 228 3.13E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16535 3038902a4915b121e2f2d9b52ebf4a2b 315 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 SUPERFAMILY SSF46894 150 225 1.02E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 218 1.7E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 SMART SM00421 162 219 5.7E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 Gene3D G3DSA:3.40.50.12740 19 225 3.2E-67 T 12-10-2018 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 Pfam PF00072 Response regulator receiver domain 21 133 2.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 3.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 3.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 3.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 SUPERFAMILY SSF52172 19 139 3.42E-30 T 12-10-2018 IPR011006 CheY-like superfamily UA74_09100 22e3f684480a5b02d7efa24364dc5df1 228 SMART SM00448 19 133 9.4E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_15605 83d9cbea239e5debefcc3c9e7a3ba73c 447 Pfam PF01546 Peptidase family M20/M25/M40 91 445 2.4E-37 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 UA74_15605 83d9cbea239e5debefcc3c9e7a3ba73c 447 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 90 99 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 UA74_15605 83d9cbea239e5debefcc3c9e7a3ba73c 447 Gene3D G3DSA:3.40.630.10 15 214 2.6E-48 T 12-10-2018 UA74_15605 83d9cbea239e5debefcc3c9e7a3ba73c 447 SUPERFAMILY SSF53187 13 445 1.17E-53 T 12-10-2018 UA74_15605 83d9cbea239e5debefcc3c9e7a3ba73c 447 Pfam PF07687 Peptidase dimerisation domain 208 344 1.3E-14 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain UA74_15605 83d9cbea239e5debefcc3c9e7a3ba73c 447 SUPERFAMILY SSF55031 211 351 1.26E-9 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UA74_16275 62d7caf4094d9c4aca3bd683edc33f7e 444 SUPERFAMILY SSF53335 15 408 1.59E-48 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_16275 62d7caf4094d9c4aca3bd683edc33f7e 444 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 78 90 - T 12-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 UA74_16275 62d7caf4094d9c4aca3bd683edc33f7e 444 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 15 31 7.3E-6 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_16275 62d7caf4094d9c4aca3bd683edc33f7e 444 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 118 132 7.3E-6 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_16275 62d7caf4094d9c4aca3bd683edc33f7e 444 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 162 175 7.3E-6 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_16275 62d7caf4094d9c4aca3bd683edc33f7e 444 Gene3D G3DSA:3.40.50.150 9 196 8.0E-39 T 12-10-2018 UA74_16275 62d7caf4094d9c4aca3bd683edc33f7e 444 Pfam PF00145 C-5 cytosine-specific DNA methylase 17 180 5.4E-27 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_26610 bd39f617ebc32d55bcf62d76699c0dbd 333 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 333 130.936 T 12-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 UA74_26610 bd39f617ebc32d55bcf62d76699c0dbd 333 Pfam PF01933 Uncharacterised protein family UPF0052 3 295 4.5E-63 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 UA74_26610 bd39f617ebc32d55bcf62d76699c0dbd 333 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 326 5.5E-117 T 12-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 UA74_26610 bd39f617ebc32d55bcf62d76699c0dbd 333 Gene3D G3DSA:3.40.50.10680 7 302 1.2E-91 T 12-10-2018 UA74_26610 bd39f617ebc32d55bcf62d76699c0dbd 333 Gene3D G3DSA:1.10.8.240 48 136 1.2E-91 T 12-10-2018 UA74_26610 bd39f617ebc32d55bcf62d76699c0dbd 333 SUPERFAMILY SSF142338 3 329 8.24E-79 T 12-10-2018 UA74_26930 6459aed22d82984c93000fd87109274f 433 Pfam PF07786 Protein of unknown function (DUF1624) 38 248 3.6E-5 T 12-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 UA74_26930 6459aed22d82984c93000fd87109274f 433 Pfam PF04235 Protein of unknown function (DUF418) 309 421 6.8E-6 T 12-10-2018 IPR007349 Domain of unknown function DUF418 UA74_24565 0bda3751334250e7298216851a92b461 248 Gene3D G3DSA:3.40.50.1400 9 126 7.3E-25 T 12-10-2018 UA74_24565 0bda3751334250e7298216851a92b461 248 Gene3D G3DSA:3.40.50.1400 129 247 1.7E-20 T 12-10-2018 UA74_24565 0bda3751334250e7298216851a92b461 248 SUPERFAMILY SSF53800 12 243 5.01E-34 T 12-10-2018 UA74_24565 0bda3751334250e7298216851a92b461 248 Pfam PF01903 CbiX 140 237 6.3E-14 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 UA74_24565 0bda3751334250e7298216851a92b461 248 Pfam PF01903 CbiX 17 115 9.2E-19 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 UA74_00290 d444f7ce27792d1701379b6e68f3ea03 131 Pfam PF13411 MerR HTH family regulatory protein 5 70 7.2E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_00290 d444f7ce27792d1701379b6e68f3ea03 131 SUPERFAMILY SSF46955 5 119 3.33E-30 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_00290 d444f7ce27792d1701379b6e68f3ea03 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 1.3E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_00290 d444f7ce27792d1701379b6e68f3ea03 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 1.3E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_00290 d444f7ce27792d1701379b6e68f3ea03 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 1.3E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_00290 d444f7ce27792d1701379b6e68f3ea03 131 Gene3D G3DSA:1.10.1660.10 4 129 1.5E-31 T 12-10-2018 UA74_00290 d444f7ce27792d1701379b6e68f3ea03 131 SMART SM00422 5 74 5.9E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13235 443768b86644f8e63eb4832197b119ec 274 SMART SM00382 31 220 7.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13235 443768b86644f8e63eb4832197b119ec 274 SUPERFAMILY SSF52540 5 232 1.51E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13235 443768b86644f8e63eb4832197b119ec 274 Pfam PF00005 ABC transporter 23 170 1.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13235 443768b86644f8e63eb4832197b119ec 274 Gene3D G3DSA:3.40.50.300 1 255 8.9E-68 T 12-10-2018 UA74_13235 443768b86644f8e63eb4832197b119ec 274 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_19075 2d97620e98258eba80f4c5e20da4428b 268 Gene3D G3DSA:1.10.150.130 71 178 3.8E-19 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_19075 2d97620e98258eba80f4c5e20da4428b 268 SUPERFAMILY SSF56349 76 238 6.36E-23 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_07985 d8e5f2f964feb68a01489569947afa9f 269 SMART SM01232 122 214 3.2E-30 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_07985 d8e5f2f964feb68a01489569947afa9f 269 SMART SM00898 2 108 6.1E-17 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_07985 d8e5f2f964feb68a01489569947afa9f 269 SUPERFAMILY SSF46946 121 205 1.91E-22 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_07985 d8e5f2f964feb68a01489569947afa9f 269 SUPERFAMILY SSF81624 2 123 2.09E-22 T 12-10-2018 IPR035937 MutM-like, N-terminal UA74_07985 d8e5f2f964feb68a01489569947afa9f 269 Gene3D G3DSA:1.10.8.50 124 268 2.2E-36 T 12-10-2018 UA74_07985 d8e5f2f964feb68a01489569947afa9f 269 Gene3D G3DSA:3.20.190.10 2 120 6.3E-11 T 12-10-2018 IPR035937 MutM-like, N-terminal UA74_07985 d8e5f2f964feb68a01489569947afa9f 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 206 1.1E-16 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_07985 d8e5f2f964feb68a01489569947afa9f 269 SUPERFAMILY SSF57716 221 267 9.41E-12 T 12-10-2018 UA74_11880 1e4e6ea8769b37d7d00f6932ef6919d2 379 Pfam PF04909 Amidohydrolase 276 377 2.9E-22 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_11880 1e4e6ea8769b37d7d00f6932ef6919d2 379 Pfam PF04909 Amidohydrolase 7 180 8.0E-16 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_11880 1e4e6ea8769b37d7d00f6932ef6919d2 379 Gene3D G3DSA:3.20.20.140 251 379 1.6E-31 T 12-10-2018 UA74_11880 1e4e6ea8769b37d7d00f6932ef6919d2 379 Gene3D G3DSA:3.20.20.140 4 197 2.7E-43 T 12-10-2018 UA74_11880 1e4e6ea8769b37d7d00f6932ef6919d2 379 SUPERFAMILY SSF51556 6 377 8.36E-34 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_07675 5cf4945b0da931e2052f290e60ad2fea 286 SUPERFAMILY SSF48452 98 252 7.21E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_07675 5cf4945b0da931e2052f290e60ad2fea 286 Pfam PF00486 Transcriptional regulatory protein, C terminal 15 79 6.4E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_07675 5cf4945b0da931e2052f290e60ad2fea 286 Gene3D G3DSA:1.25.40.10 101 259 2.3E-38 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_07675 5cf4945b0da931e2052f290e60ad2fea 286 Pfam PF03704 Bacterial transcriptional activator domain 103 244 2.1E-30 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_07675 5cf4945b0da931e2052f290e60ad2fea 286 Gene3D G3DSA:1.10.10.10 1 99 1.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_07675 5cf4945b0da931e2052f290e60ad2fea 286 SUPERFAMILY SSF46894 4 95 2.35E-13 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_07675 5cf4945b0da931e2052f290e60ad2fea 286 SMART SM00862 15 96 9.3E-13 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_07675 5cf4945b0da931e2052f290e60ad2fea 286 SMART SM01043 103 244 4.7E-36 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_11420 4284e3658aed2c41934a6712a0169882 353 SMART SM00116 226 274 0.0071 T 12-10-2018 IPR000644 CBS domain UA74_11420 4284e3658aed2c41934a6712a0169882 353 SMART SM00116 288 336 59.0 T 12-10-2018 IPR000644 CBS domain UA74_11420 4284e3658aed2c41934a6712a0169882 353 Pfam PF01595 Domain of unknown function DUF21 8 202 1.2E-41 T 12-10-2018 IPR002550 CNNM, transmembrane domain UA74_11420 4284e3658aed2c41934a6712a0169882 353 Gene3D G3DSA:3.10.580.10 199 344 5.1E-28 T 12-10-2018 UA74_11420 4284e3658aed2c41934a6712a0169882 353 Pfam PF00571 CBS domain 217 271 1.3E-4 T 12-10-2018 IPR000644 CBS domain UA74_11420 4284e3658aed2c41934a6712a0169882 353 SUPERFAMILY SSF54631 210 342 9.22E-22 T 12-10-2018 UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 SUPERFAMILY SSF49464 506 581 2.9E-11 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 Pfam PF13620 Carboxypeptidase regulatory-like domain 506 582 1.8E-11 T 12-10-2018 UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 Pfam PF13620 Carboxypeptidase regulatory-like domain 589 664 2.4E-12 T 12-10-2018 UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 429 439 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 Gene3D G3DSA:2.60.40.1120 506 583 1.2E-13 T 12-10-2018 UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 Gene3D G3DSA:2.60.40.1120 589 665 3.4E-9 T 12-10-2018 UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 SUPERFAMILY SSF52743 177 496 4.84E-62 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 Gene3D G3DSA:3.40.50.200 169 498 1.4E-67 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 SUPERFAMILY SSF49452 583 659 6.28E-11 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 PRINTS PR00723 Subtilisin serine protease family (S8) signature 251 264 3.9E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 PRINTS PR00723 Subtilisin serine protease family (S8) signature 197 216 3.9E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 PRINTS PR00723 Subtilisin serine protease family (S8) signature 428 444 3.9E-18 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_11195 caf23464d233cdbc8f8050437dcb9a7c 880 Pfam PF00082 Subtilase family 197 469 2.2E-39 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_05345 c5e6f65eb66c056e41af2f8799b013c2 280 Gene3D G3DSA:1.10.260.40 26 99 6.8E-7 T 12-10-2018 UA74_05345 c5e6f65eb66c056e41af2f8799b013c2 280 SMART SM00530 11 83 2.0E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_05345 c5e6f65eb66c056e41af2f8799b013c2 280 SUPERFAMILY SSF47413 31 82 5.0E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_05345 c5e6f65eb66c056e41af2f8799b013c2 280 Pfam PF13560 Helix-turn-helix domain 8 86 1.6E-16 T 12-10-2018 UA74_12685 5ffe72fe993e17582be6a9005b2fe00e 409 Gene3D G3DSA:2.120.10.10 44 408 4.6E-107 T 12-10-2018 UA74_12685 5ffe72fe993e17582be6a9005b2fe00e 409 SUPERFAMILY SSF50939 49 404 1.09E-92 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_12685 5ffe72fe993e17582be6a9005b2fe00e 409 Pfam PF13088 BNR repeat-like domain 72 378 1.5E-39 T 12-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_20510 0a02b0076e69c88f7a32f98ac12dba0f 258 Gene3D G3DSA:3.40.50.12500 10 248 2.0E-72 T 12-10-2018 UA74_20510 0a02b0076e69c88f7a32f98ac12dba0f 258 PIRSF PIRSF015736 5 251 2.6E-69 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 SUPERFAMILY SSF53474 1 258 6.11E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 Gene3D G3DSA:3.40.50.1820 2 266 1.8E-72 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 2.3E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.3E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.3E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 2.3E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00412 Epoxide hydrolase signature 104 117 3.9E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00412 Epoxide hydrolase signature 238 260 3.9E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00412 Epoxide hydrolase signature 46 61 3.9E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 PRINTS PR00412 Epoxide hydrolase signature 26 44 3.9E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_13430 f5ba0b424d7394ef7965b6d9ba4bb76f 272 Pfam PF00561 alpha/beta hydrolase fold 20 249 4.8E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15320 7b29fc26b26e0cb157b86792d6aee074 301 Pfam PF05368 NmrA-like family 8 235 1.3E-47 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 UA74_15320 7b29fc26b26e0cb157b86792d6aee074 301 SUPERFAMILY SSF51735 5 241 3.26E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_15320 7b29fc26b26e0cb157b86792d6aee074 301 Gene3D G3DSA:3.40.50.720 7 272 2.3E-68 T 12-10-2018 UA74_15320 7b29fc26b26e0cb157b86792d6aee074 301 Gene3D G3DSA:3.90.25.10 154 279 2.3E-68 T 12-10-2018 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 Pfam PF02983 Alpha-lytic protease prodomain 128 183 1.8E-12 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 Gene3D G3DSA:3.30.300.50 43 124 6.4E-8 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 PIRSF PIRSF001134 2 385 1.3E-123 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 SUPERFAMILY SSF50494 203 379 4.24E-34 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 SUPERFAMILY SSF54806 134 191 1.05E-5 T 12-10-2018 IPR037295 Alpha-lytic protease prodomain UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 Gene3D G3DSA:2.40.10.10 204 381 2.3E-70 T 12-10-2018 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 Pfam PF00089 Trypsin 202 374 1.9E-8 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 Gene3D G3DSA:3.30.300.50 128 194 2.4E-7 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 Gene3D G3DSA:2.40.10.10 272 370 2.3E-70 T 12-10-2018 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 224 238 6.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 324 347 6.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 348 362 6.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 284 304 6.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01955 e2f7482c73f8539806a33ec9feaf1bda 385 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 305 322 6.7E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_14600 5d63fbdf9945414d30f60ee832f97d99 277 Gene3D G3DSA:1.10.260.40 2 84 4.5E-8 T 12-10-2018 UA74_14600 5d63fbdf9945414d30f60ee832f97d99 277 SUPERFAMILY SSF47413 28 80 4.74E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_14600 5d63fbdf9945414d30f60ee832f97d99 277 Pfam PF13560 Helix-turn-helix domain 5 83 1.0E-14 T 12-10-2018 UA74_14600 5d63fbdf9945414d30f60ee832f97d99 277 SMART SM00530 9 81 4.9E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_14600 5d63fbdf9945414d30f60ee832f97d99 277 Gene3D G3DSA:3.30.450.180 108 275 1.1E-8 T 12-10-2018 UA74_10680 967a528fd517ca5a8be5c0fd879fcbca 326 Gene3D G3DSA:3.30.460.10 210 326 8.2E-14 T 12-10-2018 UA74_10680 967a528fd517ca5a8be5c0fd879fcbca 326 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 182 1.0E-48 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 UA74_10680 967a528fd517ca5a8be5c0fd879fcbca 326 SUPERFAMILY SSF52540 3 194 3.93E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10680 967a528fd517ca5a8be5c0fd879fcbca 326 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 192 26.261 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 UA74_10680 967a528fd517ca5a8be5c0fd879fcbca 326 Pfam PF04229 GrpB protein 213 325 1.1E-13 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase UA74_10680 967a528fd517ca5a8be5c0fd879fcbca 326 Pfam PF01121 Dephospho-CoA kinase 4 180 1.7E-59 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 UA74_10680 967a528fd517ca5a8be5c0fd879fcbca 326 SUPERFAMILY SSF81301 214 325 2.88E-17 T 12-10-2018 UA74_10680 967a528fd517ca5a8be5c0fd879fcbca 326 Gene3D G3DSA:3.40.50.300 1 197 1.1E-66 T 12-10-2018 UA74_04580 dc311524cf9f1abcf8a95a956c1a5db4 197 Pfam PF04542 Sigma-70 region 2 33 98 5.7E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_04580 dc311524cf9f1abcf8a95a956c1a5db4 197 Gene3D G3DSA:1.10.1740.10 19 99 2.3E-24 T 12-10-2018 UA74_04580 dc311524cf9f1abcf8a95a956c1a5db4 197 SUPERFAMILY SSF88946 29 107 1.32E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_04580 dc311524cf9f1abcf8a95a956c1a5db4 197 Pfam PF08281 Sigma-70, region 4 131 181 7.4E-17 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_04580 dc311524cf9f1abcf8a95a956c1a5db4 197 Gene3D G3DSA:1.10.10.10 129 190 4.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04580 dc311524cf9f1abcf8a95a956c1a5db4 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 185 2.7E-29 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_04580 dc311524cf9f1abcf8a95a956c1a5db4 197 SUPERFAMILY SSF88659 127 186 2.24E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_02220 3077e6707015c1b9d9e713612b0fdd8d 441 Pfam PF13439 Glycosyltransferase Family 4 37 217 1.2E-28 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_02220 3077e6707015c1b9d9e713612b0fdd8d 441 SUPERFAMILY SSF53756 36 423 2.69E-82 T 12-10-2018 UA74_02220 3077e6707015c1b9d9e713612b0fdd8d 441 Gene3D G3DSA:3.40.50.2000 22 419 3.4E-123 T 12-10-2018 UA74_02220 3077e6707015c1b9d9e713612b0fdd8d 441 Pfam PF00534 Glycosyl transferases group 1 227 396 2.4E-33 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_02220 3077e6707015c1b9d9e713612b0fdd8d 441 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 18 423 2.1E-187 T 12-10-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 UA74_02220 3077e6707015c1b9d9e713612b0fdd8d 441 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 17 427 51.171 T 12-10-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 UA74_02220 3077e6707015c1b9d9e713612b0fdd8d 441 Gene3D G3DSA:3.40.50.2000 214 403 3.4E-123 T 12-10-2018 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 Gene3D G3DSA:1.10.340.30 13 124 3.7E-70 T 12-10-2018 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 TIGRFAM TIGR01083 nth: endonuclease III 4 186 1.9E-72 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 ProSitePatterns PS01155 Endonuclease III family signature. 94 123 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 Pfam PF00633 Helix-hairpin-helix motif 91 118 7.7E-8 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 179 195 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 SUPERFAMILY SSF48150 3 200 6.28E-62 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 Hamap MF_00942 Endonuclease III [nth]. 1 201 34.462 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 27 160 7.3E-19 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 SMART SM00478 30 177 7.4E-56 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 SMART SM00525 178 198 0.0017 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 UA74_01260 d79f00c3ab741c78edb37cf1ba0aaa85 287 Gene3D G3DSA:1.10.1670.10 7 195 3.7E-70 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 UA74_03230 5371a53ebbfdda06062dd50092bfce91 365 PIRSF PIRSF000808 34 365 4.0E-105 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_03230 5371a53ebbfdda06062dd50092bfce91 365 SUPERFAMILY SSF54197 207 364 9.36E-33 T 12-10-2018 IPR036265 HIT-like superfamily UA74_03230 5371a53ebbfdda06062dd50092bfce91 365 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 178 195 - T 12-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_03230 5371a53ebbfdda06062dd50092bfce91 365 Gene3D G3DSA:3.30.428.10 71 202 9.9E-92 T 12-10-2018 IPR036265 HIT-like superfamily UA74_03230 5371a53ebbfdda06062dd50092bfce91 365 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 40 202 3.2E-40 T 12-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_03230 5371a53ebbfdda06062dd50092bfce91 365 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 42 364 1.5E-45 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_03230 5371a53ebbfdda06062dd50092bfce91 365 SUPERFAMILY SSF54197 39 203 7.37E-51 T 12-10-2018 IPR036265 HIT-like superfamily UA74_03230 5371a53ebbfdda06062dd50092bfce91 365 Gene3D G3DSA:3.30.428.10 42 362 9.9E-92 T 12-10-2018 IPR036265 HIT-like superfamily UA74_03230 5371a53ebbfdda06062dd50092bfce91 365 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 215 324 1.1E-15 T 12-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SUPERFAMILY SSF54631 332 405 1.92E-6 T 12-10-2018 UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SMART SM00267 381 543 3.6E-6 T 12-10-2018 IPR000160 GGDEF domain UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SUPERFAMILY SSF55073 397 534 4.24E-15 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 392 478 3.0E-10 T 12-10-2018 IPR000160 GGDEF domain UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SMART SM00052 6 233 5.1E-11 T 12-10-2018 IPR001633 EAL domain UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 Gene3D G3DSA:3.30.70.270 383 535 1.1E-16 T 12-10-2018 UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 SUPERFAMILY SSF141868 6 224 3.4E-37 T 12-10-2018 IPR035919 EAL domain superfamily UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 Pfam PF00563 EAL domain 7 223 2.4E-35 T 12-10-2018 IPR001633 EAL domain UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 Gene3D G3DSA:3.20.20.450 2 238 6.6E-42 T 12-10-2018 IPR035919 EAL domain superfamily UA74_12570 ba4e21c3269bfc560d6cde7f53eb6f9b 578 Pfam PF00990 Diguanylate cyclase, GGDEF domain 396 477 1.8E-10 T 12-10-2018 IPR000160 GGDEF domain UA74_25905 a313cbd0b0a4a55bef03d92bb121f889 552 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 22 38 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_25905 a313cbd0b0a4a55bef03d92bb121f889 552 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 16 548 1.5E-175 T 12-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 UA74_25905 a313cbd0b0a4a55bef03d92bb121f889 552 SMART SM00917 387 542 2.5E-36 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_25905 a313cbd0b0a4a55bef03d92bb121f889 552 SUPERFAMILY SSF110921 422 538 7.19E-25 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_25905 a313cbd0b0a4a55bef03d92bb121f889 552 Gene3D G3DSA:3.20.20.70 15 337 5.6E-95 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_25905 a313cbd0b0a4a55bef03d92bb121f889 552 Pfam PF00682 HMGL-like 16 267 3.8E-40 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 UA74_25905 a313cbd0b0a4a55bef03d92bb121f889 552 Gene3D G3DSA:3.30.160.270 410 540 1.3E-7 T 12-10-2018 UA74_25905 a313cbd0b0a4a55bef03d92bb121f889 552 Pfam PF08502 LeuA allosteric (dimerisation) domain 388 538 1.2E-24 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UA74_25905 a313cbd0b0a4a55bef03d92bb121f889 552 SUPERFAMILY SSF51569 11 305 2.38E-72 T 12-10-2018 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 Pfam PF13193 AMP-binding enzyme C-terminal domain 879 950 8.3E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_17125 ff3efe691493c4e4294824c114b61616 1055 SUPERFAMILY SSF52777 197 443 8.67E-56 T 12-10-2018 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 Pfam PF00668 Condensation domain 10 455 3.0E-93 T 12-10-2018 IPR001242 Condensation domain UA74_17125 ff3efe691493c4e4294824c114b61616 1055 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 496 895 1.0E-120 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_17125 ff3efe691493c4e4294824c114b61616 1055 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1004 1019 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17125 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:3.30.559.30 194 440 1.5E-126 T 12-10-2018 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:3.30.300.30 865 969 2.4E-30 T 12-10-2018 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:3.30.559.10 12 385 1.5E-126 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 SUPERFAMILY SSF47336 973 1046 1.7E-16 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17125 ff3efe691493c4e4294824c114b61616 1055 SUPERFAMILY SSF56801 439 993 1.83E-139 T 12-10-2018 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:1.10.1200.10 970 1049 6.1E-21 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17125 ff3efe691493c4e4294824c114b61616 1055 Pfam PF00550 Phosphopantetheine attachment site 983 1045 3.1E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17125 ff3efe691493c4e4294824c114b61616 1055 Pfam PF00501 AMP-binding enzyme 475 871 1.0E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 SMART SM00823 Phosphopantetheine attachment site 980 1049 0.0017 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 SUPERFAMILY SSF52777 13 190 1.33E-43 T 12-10-2018 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 Gene3D G3DSA:3.40.50.12780 469 864 1.0E-122 T 12-10-2018 UA74_17125 ff3efe691493c4e4294824c114b61616 1055 ProSitePatterns PS00455 Putative AMP-binding domain signature. 619 630 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_08260 4a916c04e77de7961b4ec911699705ca 204 SMART SM00855 5 157 6.7E-22 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_08260 4a916c04e77de7961b4ec911699705ca 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 197 8.7E-51 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_08260 4a916c04e77de7961b4ec911699705ca 204 Gene3D G3DSA:3.40.50.1240 2 203 6.2E-64 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_08260 4a916c04e77de7961b4ec911699705ca 204 SUPERFAMILY SSF53254 5 199 4.82E-53 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_08260 4a916c04e77de7961b4ec911699705ca 204 PIRSF PIRSF000709 4 173 6.5E-13 T 12-10-2018 UA74_08260 4a916c04e77de7961b4ec911699705ca 204 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 UA74_14995 de81729ca4135be1d834da4eec1eb565 178 Gene3D G3DSA:3.40.50.360 2 175 3.6E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_14995 de81729ca4135be1d834da4eec1eb565 178 Pfam PF03358 NADPH-dependent FMN reductase 6 133 8.4E-32 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_14995 de81729ca4135be1d834da4eec1eb565 178 SUPERFAMILY SSF52218 6 154 3.26E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_02920 67133771d26a08a09f765f2716d65caa 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 2.4E-43 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02920 67133771d26a08a09f765f2716d65caa 124 SUPERFAMILY SSF50249 2 123 2.31E-52 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_02920 67133771d26a08a09f765f2716d65caa 124 PIRSF PIRSF002133 1 124 1.1E-54 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02920 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02920 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02920 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02920 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02920 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02920 67133771d26a08a09f765f2716d65caa 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.3E-58 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02920 67133771d26a08a09f765f2716d65caa 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 3.9E-68 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02920 67133771d26a08a09f765f2716d65caa 124 Gene3D G3DSA:2.40.50.140 1 124 1.6E-63 T 12-10-2018 UA74_02920 67133771d26a08a09f765f2716d65caa 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02920 67133771d26a08a09f765f2716d65caa 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.92 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_06090 daf83819c415556a611b53e8311ecb6f 838 Pfam PF02687 FtsX-like permease family 741 831 1.1E-7 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_06090 daf83819c415556a611b53e8311ecb6f 838 Pfam PF02687 FtsX-like permease family 282 375 8.0E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 Gene3D G3DSA:2.102.10.10 53 182 6.9E-95 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 SUPERFAMILY SSF50022 20 172 2.62E-46 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 201 420 3.2E-19 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 Pfam PF00355 Rieske [2Fe-2S] domain 54 136 1.1E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 96 119 - T 12-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 SUPERFAMILY SSF55961 175 421 1.96E-43 T 12-10-2018 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 158 184 2.2E-28 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 89 109 2.2E-28 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 68 83 2.2E-28 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 110 130 2.2E-28 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 197 219 2.2E-28 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_12720 2ba0a01a11de7655142ec633a9a9de34 422 Gene3D G3DSA:3.90.380.10 29 420 6.9E-95 T 12-10-2018 UA74_26455 6f1c36924b734f78d935da4f732b9ae9 250 Gene3D G3DSA:3.90.1680.10 1 235 8.2E-67 T 12-10-2018 IPR036590 SOS response associated peptidase-like UA74_26455 6f1c36924b734f78d935da4f732b9ae9 250 Pfam PF02586 SOS response associated peptidase (SRAP) 1 223 6.9E-64 T 12-10-2018 IPR003738 SOS response associated peptidase (SRAP) UA74_26455 6f1c36924b734f78d935da4f732b9ae9 250 SUPERFAMILY SSF143081 2 235 2.75E-63 T 12-10-2018 IPR036590 SOS response associated peptidase-like UA74_13010 9bc836a66513663e493bef8644787d84 214 Pfam PF08044 Domain of unknown function (DUF1707) 13 65 4.0E-21 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 UA74_28105 368414908ad2959ad172d07b42f61e10 138 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 8 135 5.0E-46 T 12-10-2018 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable UA74_28105 368414908ad2959ad172d07b42f61e10 138 SUPERFAMILY SSF50475 3 136 4.68E-27 T 12-10-2018 UA74_28105 368414908ad2959ad172d07b42f61e10 138 Gene3D G3DSA:2.30.110.10 4 137 9.9E-44 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_28105 368414908ad2959ad172d07b42f61e10 138 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 97 2.0E-12 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_00485 fe43a18a27213d76b5dbbbe1ecf0384b 438 SUPERFAMILY SSF140459 12 175 4.18E-5 T 12-10-2018 UA74_00485 fe43a18a27213d76b5dbbbe1ecf0384b 438 PRINTS PR01228 Eggshell protein signature 306 321 4.1E-5 T 12-10-2018 UA74_00485 fe43a18a27213d76b5dbbbe1ecf0384b 438 PRINTS PR01228 Eggshell protein signature 224 235 4.1E-5 T 12-10-2018 UA74_00485 fe43a18a27213d76b5dbbbe1ecf0384b 438 PRINTS PR01228 Eggshell protein signature 383 401 4.1E-5 T 12-10-2018 UA74_00485 fe43a18a27213d76b5dbbbe1ecf0384b 438 PRINTS PR01228 Eggshell protein signature 332 342 4.1E-5 T 12-10-2018 UA74_22735 370a28cc52ce24b26213f06b11fec639 380 Pfam PF01546 Peptidase family M20/M25/M40 70 376 6.5E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 UA74_22735 370a28cc52ce24b26213f06b11fec639 380 Gene3D G3DSA:3.30.70.360 178 296 1.2E-83 T 12-10-2018 UA74_22735 370a28cc52ce24b26213f06b11fec639 380 SUPERFAMILY SSF55031 178 276 1.5E-18 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UA74_22735 370a28cc52ce24b26213f06b11fec639 380 SUPERFAMILY SSF53187 3 376 2.0E-54 T 12-10-2018 UA74_22735 370a28cc52ce24b26213f06b11fec639 380 Pfam PF07687 Peptidase dimerisation domain 174 283 1.1E-20 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain UA74_22735 370a28cc52ce24b26213f06b11fec639 380 Gene3D G3DSA:3.40.630.10 7 366 1.2E-83 T 12-10-2018 UA74_24850 dbfbf53519cd879b59dd1163187f8b7f 399 Gene3D G3DSA:2.60.40.790 325 394 2.1E-15 T 12-10-2018 IPR008978 HSP20-like chaperone UA74_24850 dbfbf53519cd879b59dd1163187f8b7f 399 Gene3D G3DSA:3.40.50.300 1 314 3.5E-79 T 12-10-2018 UA74_24850 dbfbf53519cd879b59dd1163187f8b7f 399 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 5 296 9.5E-56 T 12-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 UA74_24850 dbfbf53519cd879b59dd1163187f8b7f 399 Pfam PF02374 Anion-transporting ATPase 2 304 9.7E-64 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 UA74_24850 dbfbf53519cd879b59dd1163187f8b7f 399 SUPERFAMILY SSF52540 4 282 3.91E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF47336 914 1011 7.85E-14 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.30.70.3290 449 861 1.0E-67 T 12-10-2018 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 387 498 3.3E-14 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SMART SM00825 Beta-ketoacyl synthase 5 435 6.3E-118 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.40.366.10 523 816 1.0E-67 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF53901 2 431 1.06E-69 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 260 3.0E-56 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF52151 522 801 6.54E-32 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.30.559.30 1692 1919 1.4E-10 T 12-10-2018 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 268 383 2.8E-34 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF52777 1507 1700 7.67E-26 T 12-10-2018 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.90.1150.10 1050 1467 1.0E-104 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00202 Aminotransferase class-III 1083 1444 1.3E-41 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:1.10.1200.10 907 992 5.3E-10 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00668 Condensation domain 1510 1833 3.6E-28 T 12-10-2018 IPR001242 Condensation domain UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 1284 1320 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF53383 1062 1471 4.65E-76 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.40.47.10 1 435 1.9E-135 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.40.640.10 1121 1384 1.0E-104 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF55048 645 705 9.42E-5 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00698 Acyl transferase domain 583 781 1.8E-18 T 12-10-2018 IPR014043 Acyl transferase UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 525 842 1.7E-18 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SMART SM00823 Phosphopantetheine attachment site 921 993 5.5E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Pfam PF00550 Phosphopantetheine attachment site 923 989 8.6E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 SUPERFAMILY SSF52777 1712 1908 1.45E-9 T 12-10-2018 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 Gene3D G3DSA:3.30.559.10 1507 1691 2.3E-28 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_05150 dda735702af479c21a344837d9b9fb6d 1937 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 173 189 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_10795 5d217b194bee1c0f12adec6105a396f5 310 ProSitePatterns PS01235 PdxS/SNZ family signature. 221 239 - T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_10795 5d217b194bee1c0f12adec6105a396f5 310 Gene3D G3DSA:3.20.20.70 18 310 1.6E-151 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_10795 5d217b194bee1c0f12adec6105a396f5 310 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 25 310 5.5E-146 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_10795 5d217b194bee1c0f12adec6105a396f5 310 Pfam PF01680 SOR/SNZ family 23 228 1.5E-107 T 12-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_10795 5d217b194bee1c0f12adec6105a396f5 310 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 20 310 53.57 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_10795 5d217b194bee1c0f12adec6105a396f5 310 SUPERFAMILY SSF51366 34 280 2.97E-63 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UA74_10795 5d217b194bee1c0f12adec6105a396f5 310 PIRSF PIRSF029271 13 310 8.5E-152 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_16170 17568888f8c1e4f540554823fce8c660 389 Gene3D G3DSA:3.40.50.300 147 308 5.6E-20 T 12-10-2018 UA74_16170 17568888f8c1e4f540554823fce8c660 389 SUPERFAMILY SSF52540 150 315 6.54E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16170 17568888f8c1e4f540554823fce8c660 389 Pfam PF07728 AAA domain (dynein-related subfamily) 162 290 4.6E-15 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 UA74_15540 261e8aa37aa599b21b691952ac09de69 223 Gene3D G3DSA:1.10.10.10 1 78 7.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_15540 261e8aa37aa599b21b691952ac09de69 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 4.5E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_15540 261e8aa37aa599b21b691952ac09de69 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 4.5E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_15540 261e8aa37aa599b21b691952ac09de69 223 SUPERFAMILY SSF48008 83 215 3.14E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_15540 261e8aa37aa599b21b691952ac09de69 223 SUPERFAMILY SSF46785 10 81 3.67E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_15540 261e8aa37aa599b21b691952ac09de69 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 1.1E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_15540 261e8aa37aa599b21b691952ac09de69 223 SMART SM00345 19 77 3.0E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_15540 261e8aa37aa599b21b691952ac09de69 223 SMART SM00895 87 210 2.3E-11 T 12-10-2018 IPR011711 GntR, C-terminal UA74_15540 261e8aa37aa599b21b691952ac09de69 223 Pfam PF07729 FCD domain 91 209 2.1E-18 T 12-10-2018 IPR011711 GntR, C-terminal UA74_15540 261e8aa37aa599b21b691952ac09de69 223 Gene3D G3DSA:1.20.120.530 81 219 4.7E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 SUPERFAMILY SSF51735 14 171 2.6E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 SUPERFAMILY SSF69055 313 406 1.23E-24 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 16 405 43.073 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 Gene3D G3DSA:1.10.1740.10 324 408 6.3E-27 T 12-10-2018 UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 PIRSF PIRSF006205 13 410 1.4E-133 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 SUPERFAMILY SSF55347 149 285 3.07E-54 T 12-10-2018 UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 Pfam PF13288 DXP reductoisomerase C-terminal domain 283 400 7.7E-31 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 15 403 7.7E-111 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 Gene3D G3DSA:3.40.50.720 7 171 6.4E-43 T 12-10-2018 UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 167 250 1.3E-36 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UA74_09010 fb5a9b531fd2d024de068b92cbef765b 418 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 16 155 1.0E-34 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UA74_25715 1d8721853695ab4f755366d11a2054c0 216 SMART SM00986 44 203 5.2E-29 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_25715 1d8721853695ab4f755366d11a2054c0 216 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 2 214 32.951 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_25715 1d8721853695ab4f755366d11a2054c0 216 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 52 61 - T 12-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_25715 1d8721853695ab4f755366d11a2054c0 216 SUPERFAMILY SSF52141 2 214 1.22E-69 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_25715 1d8721853695ab4f755366d11a2054c0 216 SMART SM00987 44 203 5.2E-29 T 12-10-2018 UA74_25715 1d8721853695ab4f755366d11a2054c0 216 Gene3D G3DSA:3.40.470.10 1 216 8.9E-81 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_25715 1d8721853695ab4f755366d11a2054c0 216 Pfam PF03167 Uracil DNA glycosylase superfamily 47 202 1.9E-16 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UA74_14445 b3459ac8b1a8a444caf785b5dfce9ce8 256 Pfam PF00975 Thioesterase domain 24 247 1.2E-53 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_14445 b3459ac8b1a8a444caf785b5dfce9ce8 256 SMART SM00824 Thioesterase 26 248 1.6E-4 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_14445 b3459ac8b1a8a444caf785b5dfce9ce8 256 SUPERFAMILY SSF53474 9 248 2.53E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_14445 b3459ac8b1a8a444caf785b5dfce9ce8 256 Gene3D G3DSA:3.40.50.1820 5 250 2.9E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 Pfam PF00381 PTS HPr component phosphorylation site 197 275 4.5E-20 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 PRINTS PR00107 Phosphocarrier protein signature 247 264 7.6E-9 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 PRINTS PR00107 Phosphocarrier protein signature 232 247 7.6E-9 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 PRINTS PR00107 Phosphocarrier protein signature 207 223 7.6E-9 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 Gene3D G3DSA:3.40.50.510 1 129 2.1E-41 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 Gene3D G3DSA:3.30.1340.10 196 281 6.9E-21 T 12-10-2018 IPR035895 HPr-like superfamily UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 207 214 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 Pfam PF03610 PTS system fructose IIA component 5 116 1.5E-23 T 12-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 4 120 2.9E-35 T 12-10-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 SUPERFAMILY SSF53062 4 122 3.4E-29 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 SUPERFAMILY SSF55594 198 279 6.67E-21 T 12-10-2018 IPR035895 HPr-like superfamily UA74_07165 4ae141e9c891c90be703f47b6e9586ee 281 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 199 274 9.6E-20 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_27275 ba1799c23329bac48119f42e6fa63b88 215 Hamap MF_00165 Thymidylate kinase [tmk]. 13 207 17.031 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_27275 ba1799c23329bac48119f42e6fa63b88 215 SUPERFAMILY SSF52540 11 204 3.22E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_27275 ba1799c23329bac48119f42e6fa63b88 215 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 11 193 2.2E-33 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_27275 ba1799c23329bac48119f42e6fa63b88 215 Pfam PF02223 Thymidylate kinase 17 171 7.6E-32 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 UA74_27275 ba1799c23329bac48119f42e6fa63b88 215 Gene3D G3DSA:3.40.50.300 11 208 7.7E-42 T 12-10-2018 UA74_06870 b95f32a7de5150d7e2645eb66e6e3d32 198 Pfam PF03641 Possible lysine decarboxylase 41 169 6.1E-44 T 12-10-2018 IPR031100 LOG family UA74_06870 b95f32a7de5150d7e2645eb66e6e3d32 198 Gene3D G3DSA:3.40.50.450 1 189 1.8E-74 T 12-10-2018 UA74_06870 b95f32a7de5150d7e2645eb66e6e3d32 198 SUPERFAMILY SSF102405 1 174 1.4E-60 T 12-10-2018 UA74_06870 b95f32a7de5150d7e2645eb66e6e3d32 198 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 1 174 2.1E-57 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG UA74_25415 02a9e556efdace6e7421f58766ceb69f 322 Gene3D G3DSA:3.30.70.250 131 194 6.2E-85 T 12-10-2018 UA74_25415 02a9e556efdace6e7421f58766ceb69f 322 Pfam PF00698 Acyl transferase domain 12 290 1.7E-23 T 12-10-2018 IPR014043 Acyl transferase UA74_25415 02a9e556efdace6e7421f58766ceb69f 322 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 10 311 3.0E-15 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_25415 02a9e556efdace6e7421f58766ceb69f 322 SUPERFAMILY SSF52151 6 310 1.41E-64 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_25415 02a9e556efdace6e7421f58766ceb69f 322 SUPERFAMILY SSF55048 133 185 1.57E-10 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_25415 02a9e556efdace6e7421f58766ceb69f 322 Gene3D G3DSA:3.40.366.10 8 284 6.2E-85 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_18765 40c4e3fdba801cc8d18f7ee2f513c97f 429 SUPERFAMILY SSF53850 25 422 1.72E-58 T 12-10-2018 UA74_18765 40c4e3fdba801cc8d18f7ee2f513c97f 429 Gene3D G3DSA:3.40.190.10 152 409 4.8E-72 T 12-10-2018 UA74_18765 40c4e3fdba801cc8d18f7ee2f513c97f 429 Gene3D G3DSA:3.40.190.10 50 373 4.8E-72 T 12-10-2018 UA74_18765 40c4e3fdba801cc8d18f7ee2f513c97f 429 Pfam PF13416 Bacterial extracellular solute-binding protein 57 354 2.2E-26 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 SMART SM00448 2 115 1.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 Pfam PF00072 Response regulator receiver domain 4 115 1.6E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.1E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.1E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.1E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 SUPERFAMILY SSF46894 142 210 9.52E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 SMART SM00421 151 208 3.9E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 Gene3D G3DSA:3.40.50.12740 2 213 3.5E-56 T 12-10-2018 UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 206 2.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_19915 c2de927d2c6cc8fd90934dffc6535b5e 214 SUPERFAMILY SSF52172 2 129 1.15E-31 T 12-10-2018 IPR011006 CheY-like superfamily UA74_04985 d50875d6a16922a85b747309f2293b8d 860 Gene3D G3DSA:1.20.120.1080 373 455 3.5E-5 T 12-10-2018 UA74_04985 d50875d6a16922a85b747309f2293b8d 860 Pfam PF04408 Helicase associated domain (HA2) 389 445 6.4E-9 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 UA74_04985 d50875d6a16922a85b747309f2293b8d 860 SMART SM00490 228 326 2.3E-14 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_04985 d50875d6a16922a85b747309f2293b8d 860 Pfam PF00271 Helicase conserved C-terminal domain 210 326 3.0E-11 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_04985 d50875d6a16922a85b747309f2293b8d 860 Gene3D G3DSA:3.40.50.300 3 181 4.4E-50 T 12-10-2018 UA74_04985 d50875d6a16922a85b747309f2293b8d 860 Pfam PF08482 ATP-dependent helicase C-terminal 717 848 1.5E-52 T 12-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal UA74_04985 d50875d6a16922a85b747309f2293b8d 860 Gene3D G3DSA:3.40.50.300 182 344 6.2E-46 T 12-10-2018 UA74_04985 d50875d6a16922a85b747309f2293b8d 860 SUPERFAMILY SSF52540 20 336 5.19E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04985 d50875d6a16922a85b747309f2293b8d 860 PIRSF PIRSF005496 507 860 4.9E-107 T 12-10-2018 UA74_04985 d50875d6a16922a85b747309f2293b8d 860 PIRSF PIRSF005496 4 498 2.0E-171 T 12-10-2018 UA74_04985 d50875d6a16922a85b747309f2293b8d 860 SMART SM00487 7 188 3.7E-19 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_04985 d50875d6a16922a85b747309f2293b8d 860 SMART SM00847 386 479 2.6E-5 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 SMART SM01043 103 245 3.2E-36 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 Gene3D G3DSA:1.10.10.10 1 98 2.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 Pfam PF03704 Bacterial transcriptional activator domain 104 245 7.0E-32 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 Pfam PF00931 NB-ARC domain 367 475 1.3E-7 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 94 1.4E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 SUPERFAMILY SSF52540 288 488 1.6E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 SUPERFAMILY SSF48452 104 264 5.69E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 SUPERFAMILY SSF46894 5 96 4.82E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 Gene3D G3DSA:1.25.40.10 101 276 3.1E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_14775 65043175c08cfb3c66247896c6e8c8e4 620 SMART SM00862 19 96 1.6E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_17660 2c90751eec34d295c1d47d9d5a1247ed 629 Gene3D G3DSA:3.80.30.20 259 432 1.8E-8 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UA74_17660 2c90751eec34d295c1d47d9d5a1247ed 629 SUPERFAMILY SSF102114 260 456 1.49E-18 T 12-10-2018 UA74_17660 2c90751eec34d295c1d47d9d5a1247ed 629 Pfam PF02310 B12 binding domain 113 197 1.9E-10 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_17660 2c90751eec34d295c1d47d9d5a1247ed 629 TIGRFAM TIGR03975 rSAM_ocin_1: ribosomal peptide maturation radical SAM protein 1 3 602 7.4E-172 T 12-10-2018 IPR023984 Ribosomal peptide maturation radical SAM protein 1 UA74_17660 2c90751eec34d295c1d47d9d5a1247ed 629 SMART SM00729 260 475 4.7E-10 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_22370 cca8a5a18f8217cf108c6a5edf1ac782 282 Pfam PF13460 NAD(P)H-binding 13 106 1.6E-15 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_22370 cca8a5a18f8217cf108c6a5edf1ac782 282 Gene3D G3DSA:3.40.50.720 10 262 3.0E-54 T 12-10-2018 UA74_22370 cca8a5a18f8217cf108c6a5edf1ac782 282 Gene3D G3DSA:3.90.25.10 131 264 3.0E-54 T 12-10-2018 UA74_22370 cca8a5a18f8217cf108c6a5edf1ac782 282 SUPERFAMILY SSF51735 7 272 4.92E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_09260 341921386d49b0afb535bb4262739d0b 256 SUPERFAMILY SSF51735 7 254 7.38E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_09260 341921386d49b0afb535bb4262739d0b 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_09260 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09260 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09260 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09260 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09260 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09260 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09260 341921386d49b0afb535bb4262739d0b 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 254 1.9E-70 T 12-10-2018 UA74_09260 341921386d49b0afb535bb4262739d0b 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 195 0.0084 T 12-10-2018 UA74_09260 341921386d49b0afb535bb4262739d0b 256 Gene3D G3DSA:3.40.50.720 4 255 1.7E-84 T 12-10-2018 UA74_09260 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09260 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09260 341921386d49b0afb535bb4262739d0b 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.3E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17000 e91263ebaed0a56e14e369fa14093235 103 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 94 5.8E-21 T 12-10-2018 UA74_17000 e91263ebaed0a56e14e369fa14093235 103 Gene3D G3DSA:3.10.20.440 4 99 1.9E-17 T 12-10-2018 UA74_17000 e91263ebaed0a56e14e369fa14093235 103 SUPERFAMILY SSF54292 18 98 8.59E-15 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 UA74_02900 031895a45206c70509877948bc193392 201 SUPERFAMILY SSF46894 131 201 1.12E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_02900 031895a45206c70509877948bc193392 201 SUPERFAMILY SSF52172 1 129 7.83E-30 T 12-10-2018 IPR011006 CheY-like superfamily UA74_02900 031895a45206c70509877948bc193392 201 Pfam PF00072 Response regulator receiver domain 4 116 1.0E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_02900 031895a45206c70509877948bc193392 201 Gene3D G3DSA:3.40.50.12740 2 201 1.9E-53 T 12-10-2018 UA74_02900 031895a45206c70509877948bc193392 201 SMART SM00448 2 115 4.6E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_02900 031895a45206c70509877948bc193392 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_02900 031895a45206c70509877948bc193392 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.2E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_02900 031895a45206c70509877948bc193392 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.2E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_02900 031895a45206c70509877948bc193392 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.2E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_02900 031895a45206c70509877948bc193392 201 SMART SM00421 138 195 2.4E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_14380 a939ae9243ce40b4ae117379da23d7f9 497 SUPERFAMILY SSF53720 24 496 1.7E-165 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_14380 a939ae9243ce40b4ae117379da23d7f9 497 Gene3D G3DSA:3.40.309.10 272 462 4.4E-179 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_14380 a939ae9243ce40b4ae117379da23d7f9 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 268 275 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UA74_14380 a939ae9243ce40b4ae117379da23d7f9 497 Pfam PF00171 Aldehyde dehydrogenase family 37 493 1.3E-166 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_14380 a939ae9243ce40b4ae117379da23d7f9 497 Gene3D G3DSA:3.40.605.10 38 491 4.4E-179 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_22350 e9e5fb68ad1e00858a79b590f0412955 213 SUPERFAMILY SSF48498 66 172 2.11E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_22350 e9e5fb68ad1e00858a79b590f0412955 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 45 3.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22350 e9e5fb68ad1e00858a79b590f0412955 213 Gene3D G3DSA:1.10.357.10 1 173 2.5E-32 T 12-10-2018 UA74_22350 e9e5fb68ad1e00858a79b590f0412955 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 43 1.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22350 e9e5fb68ad1e00858a79b590f0412955 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 12 1.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22350 e9e5fb68ad1e00858a79b590f0412955 213 SUPERFAMILY SSF46689 13 69 1.05E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_25095 71bd4e8a18f02a33eacd9d3c3fc1aa56 372 Hamap MF_00206 Lipoyl synthase [lipA]. 63 346 131.745 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_25095 71bd4e8a18f02a33eacd9d3c3fc1aa56 372 Gene3D G3DSA:3.20.20.70 112 319 2.4E-16 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_25095 71bd4e8a18f02a33eacd9d3c3fc1aa56 372 Pfam PF04055 Radical SAM superfamily 120 274 5.1E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_25095 71bd4e8a18f02a33eacd9d3c3fc1aa56 372 PIRSF PIRSF005963 19 355 2.8E-119 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_25095 71bd4e8a18f02a33eacd9d3c3fc1aa56 372 SMART SM00729 110 315 9.4E-14 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_25095 71bd4e8a18f02a33eacd9d3c3fc1aa56 372 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 63 99 1.6E-7 T 12-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_25095 71bd4e8a18f02a33eacd9d3c3fc1aa56 372 SUPERFAMILY SSF102114 74 335 5.76E-61 T 12-10-2018 UA74_25095 71bd4e8a18f02a33eacd9d3c3fc1aa56 372 TIGRFAM TIGR00510 lipA: lipoyl synthase 56 342 3.1E-96 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 6.7E-24 T 12-10-2018 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 PRINTS PR00419 Adrenodoxin reductase family signature 178 191 6.7E-24 T 12-10-2018 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 PRINTS PR00419 Adrenodoxin reductase family signature 155 177 6.7E-24 T 12-10-2018 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 PRINTS PR00419 Adrenodoxin reductase family signature 220 230 6.7E-24 T 12-10-2018 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 SUPERFAMILY SSF51971 382 480 2.35E-10 T 12-10-2018 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 39 140 5.3E-19 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 SUPERFAMILY SSF46548 6 164 1.26E-28 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 155 470 1.3E-26 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 Gene3D G3DSA:3.50.50.60 286 482 4.5E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 SUPERFAMILY SSF51971 153 415 9.81E-61 T 12-10-2018 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 Gene3D G3DSA:3.50.50.60 152 285 3.0E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 4 488 1.1E-183 T 12-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 UA74_21335 e7ff76e2e56f5d69a8677da52194b9d1 501 Gene3D G3DSA:1.10.1060.10 17 151 1.7E-18 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 Gene3D G3DSA:3.30.559.30 197 440 2.7E-120 T 12-10-2018 UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 SUPERFAMILY SSF47336 613 685 1.44E-17 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 SMART SM00823 Phosphopantetheine attachment site 496 565 4.6E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 SMART SM00823 Phosphopantetheine attachment site 620 689 0.0077 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 SUPERFAMILY SSF47336 489 562 3.93E-19 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 SUPERFAMILY SSF53474 687 929 6.42E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 Pfam PF00975 Thioesterase domain 707 914 8.5E-20 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 Pfam PF00668 Condensation domain 21 445 2.0E-86 T 12-10-2018 IPR001242 Condensation domain UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 SUPERFAMILY SSF52777 200 441 5.56E-48 T 12-10-2018 UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 Gene3D G3DSA:3.30.559.10 22 385 2.7E-120 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 SUPERFAMILY SSF52777 24 193 2.11E-43 T 12-10-2018 UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 Pfam PF00550 Phosphopantetheine attachment site 500 561 4.6E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 Pfam PF00550 Phosphopantetheine attachment site 623 685 2.0E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 Gene3D G3DSA:3.40.50.1820 485 595 2.0E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05210 8b26f1979ec31fb7868d1ee5153b0ff4 934 Gene3D G3DSA:3.40.50.1820 609 932 1.6E-85 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_21420 d4b661fb787a9d14501e0a5757f83591 196 Gene3D G3DSA:1.10.10.10 108 179 5.6E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21420 d4b661fb787a9d14501e0a5757f83591 196 Pfam PF12840 Helix-turn-helix domain 112 169 9.6E-9 T 12-10-2018 UA74_21420 d4b661fb787a9d14501e0a5757f83591 196 SUPERFAMILY SSF46785 105 172 1.19E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 123 134 5.4E-21 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 212 223 5.4E-21 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 299 311 5.4E-21 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 241 259 5.4E-21 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 PRINTS PR00110 Alpha-amylase signature 91 108 5.4E-21 T 12-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 Gene3D G3DSA:2.60.40.10 489 591 3.2E-33 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 SMART SM01065 495 587 1.1E-30 T 12-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 SUPERFAMILY SSF51011 391 479 7.71E-32 T 12-10-2018 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 SUPERFAMILY SSF51445 47 387 1.66E-78 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 Pfam PF00128 Alpha amylase, catalytic domain 101 345 1.2E-18 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 SMART SM00632 394 480 3.3E-44 T 12-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 Gene3D G3DSA:2.60.40.1180 391 480 3.9E-33 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 SUPERFAMILY SSF49452 499 590 3.43E-31 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 Gene3D G3DSA:3.20.20.80 47 390 5.3E-137 T 12-10-2018 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 SMART SM00642 48 385 4.0E-74 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 397 477 1.5E-15 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 UA74_18130 dad373118d02ce4af0ed7fb98a0f46ea 591 Pfam PF00686 Starch binding domain 499 582 4.8E-29 T 12-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 Pfam PF05697 Bacterial trigger factor protein (TF) 2 145 2.1E-36 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 PIRSF PIRSF003095 1 443 4.1E-108 T 12-10-2018 IPR005215 Trigger factor GO:0015031 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 Gene3D G3DSA:3.30.70.1050 1 116 2.0E-30 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 SUPERFAMILY SSF109998 246 434 9.81E-41 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 SUPERFAMILY SSF54534 133 244 5.3E-19 T 12-10-2018 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 TIGRFAM TIGR00115 tig: trigger factor 12 415 1.3E-111 T 12-10-2018 IPR005215 Trigger factor GO:0015031 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 Gene3D G3DSA:3.10.50.40 151 243 1.9E-60 T 12-10-2018 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 Hamap MF_00303 Trigger factor [tig]. 1 424 18.515 T 12-10-2018 IPR005215 Trigger factor GO:0015031 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 Gene3D G3DSA:1.10.3120.10 117 423 1.9E-60 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 SUPERFAMILY SSF102735 2 128 5.49E-31 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 UA74_08065 1f1a7d615371352efe0160dc744cabfb 477 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 416 4.9E-33 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 UA74_17030 fb83e941d1c799d2d5c589f131ddf1f5 275 Pfam PF00005 ABC transporter 32 188 1.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_17030 fb83e941d1c799d2d5c589f131ddf1f5 275 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_17030 fb83e941d1c799d2d5c589f131ddf1f5 275 Gene3D G3DSA:3.40.50.300 10 274 9.1E-81 T 12-10-2018 UA74_17030 fb83e941d1c799d2d5c589f131ddf1f5 275 SUPERFAMILY SSF52540 12 260 1.61E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_17030 fb83e941d1c799d2d5c589f131ddf1f5 275 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 270 8.4E-6 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_17030 fb83e941d1c799d2d5c589f131ddf1f5 275 SMART SM00382 40 238 5.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 SUPERFAMILY SSF51735 8 248 7.38E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 247 4.3E-55 T 12-10-2018 UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 Gene3D G3DSA:3.40.50.720 2 248 2.3E-73 T 12-10-2018 UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_20350 87e6fa7c5a68b8344a64c3aa6d46b40c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_20025 e0fab47e3ec9c39a1805e36ce79f165f 379 Gene3D G3DSA:2.40.50.100 239 364 8.9E-19 T 12-10-2018 UA74_20025 e0fab47e3ec9c39a1805e36ce79f165f 379 Pfam PF08402 TOBE domain 282 359 1.2E-8 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 UA74_20025 e0fab47e3ec9c39a1805e36ce79f165f 379 Pfam PF00005 ABC transporter 20 161 3.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_20025 e0fab47e3ec9c39a1805e36ce79f165f 379 SUPERFAMILY SSF50331 236 367 2.07E-25 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UA74_20025 e0fab47e3ec9c39a1805e36ce79f165f 379 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_20025 e0fab47e3ec9c39a1805e36ce79f165f 379 SUPERFAMILY SSF52540 4 242 8.4E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20025 e0fab47e3ec9c39a1805e36ce79f165f 379 Gene3D G3DSA:3.40.50.300 1 238 1.2E-68 T 12-10-2018 UA74_20025 e0fab47e3ec9c39a1805e36ce79f165f 379 SMART SM00382 28 211 4.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20025 e0fab47e3ec9c39a1805e36ce79f165f 379 Gene3D G3DSA:2.40.50.140 285 352 8.9E-19 T 12-10-2018 UA74_00310 1b6eb54e8310f9f8b3fc89a394d48f64 486 Pfam PF01757 Acyltransferase family 117 437 7.0E-21 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_12090 0c5dbb5e379cdcad69b42e0e0f028b39 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site UA74_12090 0c5dbb5e379cdcad69b42e0e0f028b39 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 3.1E-23 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_12090 0c5dbb5e379cdcad69b42e0e0f028b39 89 Pfam PF00381 PTS HPr component phosphorylation site 3 83 1.1E-23 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_12090 0c5dbb5e379cdcad69b42e0e0f028b39 89 PRINTS PR00107 Phosphocarrier protein signature 54 71 3.0E-12 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_12090 0c5dbb5e379cdcad69b42e0e0f028b39 89 PRINTS PR00107 Phosphocarrier protein signature 39 54 3.0E-12 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_12090 0c5dbb5e379cdcad69b42e0e0f028b39 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.0E-12 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_12090 0c5dbb5e379cdcad69b42e0e0f028b39 89 SUPERFAMILY SSF55594 1 87 1.7E-21 T 12-10-2018 IPR035895 HPr-like superfamily UA74_12090 0c5dbb5e379cdcad69b42e0e0f028b39 89 Gene3D G3DSA:3.30.1340.10 1 86 5.2E-24 T 12-10-2018 IPR035895 HPr-like superfamily UA74_20965 fbf3104067bd1529028d5bef42a8df77 305 SUPERFAMILY SSF56219 4 282 2.36E-18 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_20965 fbf3104067bd1529028d5bef42a8df77 305 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 136 275 9.6E-9 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase UA74_05790 3c5e11853ccd999afb3d51d0c96b8838 381 Pfam PF12698 ABC-2 family transporter protein 24 370 1.1E-33 T 12-10-2018 UA74_18695 88b837de7d3fd6800c3fe3077405fdd9 410 SUPERFAMILY SSF46785 331 409 4.6E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 Pfam PF00106 short chain dehydrogenase 7 199 3.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 SUPERFAMILY SSF51735 7 248 1.83E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 Gene3D G3DSA:3.40.50.720 1 252 6.1E-65 T 12-10-2018 UA74_00280 b1720da2f80b720dcc0f58d419bea227 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 193 0.0038 T 12-10-2018 UA74_07715 65da55deccaa081d413a1608ecf5d469 340 SUPERFAMILY SSF51679 7 329 5.23E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_07715 65da55deccaa081d413a1608ecf5d469 340 Gene3D G3DSA:3.20.20.30 3 335 6.5E-104 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_07715 65da55deccaa081d413a1608ecf5d469 340 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 8 330 3.2E-119 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 UA74_07715 65da55deccaa081d413a1608ecf5d469 340 Pfam PF00296 Luciferase-like monooxygenase 14 306 2.7E-39 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_14535 e400e72be1c29017da17be3acc1f81d1 170 Gene3D G3DSA:1.10.10.10 14 156 2.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14535 e400e72be1c29017da17be3acc1f81d1 170 Pfam PF12802 MarR family 43 102 1.1E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14535 e400e72be1c29017da17be3acc1f81d1 170 SMART SM00347 37 140 7.3E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14535 e400e72be1c29017da17be3acc1f81d1 170 SUPERFAMILY SSF46785 12 153 6.42E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20420 0d933a5625c5f90cdf3c5d8ace8cacb5 380 Gene3D G3DSA:3.40.50.720 137 317 2.0E-50 T 12-10-2018 UA74_20420 0d933a5625c5f90cdf3c5d8ace8cacb5 380 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 211 362 2.5E-13 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_20420 0d933a5625c5f90cdf3c5d8ace8cacb5 380 SUPERFAMILY SSF52283 12 180 2.21E-27 T 12-10-2018 UA74_20420 0d933a5625c5f90cdf3c5d8ace8cacb5 380 Gene3D G3DSA:3.40.50.720 13 362 2.0E-50 T 12-10-2018 UA74_20420 0d933a5625c5f90cdf3c5d8ace8cacb5 380 SMART SM01002 147 309 1.1E-14 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_20420 0d933a5625c5f90cdf3c5d8ace8cacb5 380 SUPERFAMILY SSF51735 144 315 7.35E-17 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_20420 0d933a5625c5f90cdf3c5d8ace8cacb5 380 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 13 125 1.4E-13 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UA74_20420 0d933a5625c5f90cdf3c5d8ace8cacb5 380 SMART SM01003 7 144 1.5E-18 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF52151 2107 2397 1.41E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF47336 2986 3095 1.83E-22 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF47336 4509 4596 4.84E-20 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 4228 4484 3.66E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 4026 4218 1.55E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 2510 2694 3.33E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.47.10 23 494 2.2E-179 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.47.10 1571 2027 1.0E-186 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1209 1388 2.5E-45 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4231 4411 8.1E-48 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2705 2885 1.1E-57 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.50.720 946 1460 4.7E-159 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.50.720 3980 4484 7.5E-154 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF08990 Erythronolide synthase docking 2 26 6.2E-12 T 12-10-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF53901 1578 1952 3.32E-104 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.30.70.3290 3517 3969 3.1E-150 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00550 Phosphopantetheine attachment site 4517 4582 2.9E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00550 Phosphopantetheine attachment site 1492 1557 7.3E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00550 Phosphopantetheine attachment site 2990 3056 2.7E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 283 6.4E-84 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3080 3323 4.1E-84 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1580 1830 3.6E-88 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF53901 29 404 1.59E-93 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:1.10.1200.10 1471 1563 5.6E-32 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF52151 589 882 2.01E-68 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 2702 2936 1.42E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF52151 3599 3908 1.36E-64 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.50.720 2465 2959 1.1E-155 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00825 Beta-ketoacyl synthase 3082 3501 6.5E-206 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00825 Beta-ketoacyl synthase 35 461 3.6E-209 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00825 Beta-ketoacyl synthase 1582 2008 7.8E-221 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF55048 723 784 8.5E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1516 1531 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:1.10.1200.10 4495 4587 3.3E-30 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:1.10.1200.10 2968 3061 2.8E-33 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF08659 KR domain 4231 4409 2.0E-60 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF08659 KR domain 1209 1386 3.7E-54 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF08659 KR domain 2705 2883 1.1E-62 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 989 1196 4.33E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3236 3252 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1838 1955 6.6E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 408 5.9E-42 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3331 3448 1.2E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 555 2.8E-12 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3451 3562 7.1E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1958 2074 5.8E-16 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00823 Phosphopantetheine attachment site 2988 3060 5.1E-28 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00823 Phosphopantetheine attachment site 4515 4587 7.9E-29 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00823 Phosphopantetheine attachment site 1489 1561 5.1E-31 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF53901 3078 3438 6.98E-99 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF51735 1203 1463 8.0E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF55048 2238 2299 2.35E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM01294 2989 3056 1.0E-5 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM01294 1490 1557 1.4E-6 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM01294 4516 4583 1.9E-7 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3015 3030 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3602 3922 1.9E-107 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2111 2404 2.4E-113 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 592 889 1.4E-112 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.47.10 3073 3502 1.3E-175 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1743 1759 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00698 Acyl transferase domain 592 907 1.8E-52 T 12-10-2018 IPR014043 Acyl transferase UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00698 Acyl transferase domain 2111 2422 6.2E-50 T 12-10-2018 IPR014043 Acyl transferase UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Pfam PF00698 Acyl transferase domain 3601 3941 5.7E-47 T 12-10-2018 IPR014043 Acyl transferase UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF47336 1485 1595 2.36E-22 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.366.10 3600 3926 3.1E-150 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF101173 2 30 9.42E-5 T 12-10-2018 IPR036299 Polyketide synthase, docking domain superfmaily UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.366.10 2109 2407 2.1E-164 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.40.366.10 590 892 1.2E-158 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.30.70.3290 2028 2449 2.1E-164 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 Gene3D G3DSA:3.30.70.3290 504 935 1.2E-158 T 12-10-2018 UA74_16460 416737eca8bbdcd3c30e5eabec54e659 4665 SUPERFAMILY SSF55048 3729 3813 3.79E-8 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_19205 78b9e9bc51942baa10b7b3d6c6edbce3 195 SUPERFAMILY SSF55166 66 175 1.02E-20 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_19205 78b9e9bc51942baa10b7b3d6c6edbce3 195 Gene3D G3DSA:3.30.1380.10 47 177 2.1E-15 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_19205 78b9e9bc51942baa10b7b3d6c6edbce3 195 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 68 142 2.5E-11 T 12-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 UA74_13050 03840b51be7e0b416e70e0285687be6c 353 SUPERFAMILY SSF51735 4 322 1.81E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_13050 03840b51be7e0b416e70e0285687be6c 353 Gene3D G3DSA:3.40.50.720 1 326 4.2E-45 T 12-10-2018 UA74_13050 03840b51be7e0b416e70e0285687be6c 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 230 3.5E-19 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_26135 95fd8e0f1243a78b699dd1d23125aae1 328 SUPERFAMILY SSF51679 1 318 5.1E-73 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_26135 95fd8e0f1243a78b699dd1d23125aae1 328 Gene3D G3DSA:3.20.20.30 1 319 4.2E-83 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_26135 95fd8e0f1243a78b699dd1d23125aae1 328 Pfam PF00296 Luciferase-like monooxygenase 1 295 2.7E-55 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_29540 fd4157eb5219fe5ca723b67db7e1529f 237 Gene3D G3DSA:3.40.50.150 23 237 8.9E-64 T 12-10-2018 UA74_29540 fd4157eb5219fe5ca723b67db7e1529f 237 Pfam PF02390 Putative methyltransferase 59 226 9.7E-51 T 12-10-2018 UA74_29540 fd4157eb5219fe5ca723b67db7e1529f 237 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 17 236 28.547 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 UA74_29540 fd4157eb5219fe5ca723b67db7e1529f 237 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 54 235 4.3E-40 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 UA74_29540 fd4157eb5219fe5ca723b67db7e1529f 237 SUPERFAMILY SSF53335 7 235 3.93E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_19985 6e2e6f3b850628fc49c6f303da87939c 266 Pfam PF01261 Xylose isomerase-like TIM barrel 29 192 2.1E-24 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_19985 6e2e6f3b850628fc49c6f303da87939c 266 SUPERFAMILY SSF51658 11 262 3.73E-33 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_19985 6e2e6f3b850628fc49c6f303da87939c 266 Gene3D G3DSA:3.20.20.150 16 263 2.5E-35 T 12-10-2018 UA74_24830 93c724f49687c8c8fc130ac9bd10e2a9 256 Pfam PF12146 Serine aminopeptidase, S33 20 218 4.9E-18 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 UA74_24830 93c724f49687c8c8fc130ac9bd10e2a9 256 PIRSF PIRSF017388 3 248 4.4E-61 T 12-10-2018 IPR012354 Esterase/lipase GO:0052689 UA74_24830 93c724f49687c8c8fc130ac9bd10e2a9 256 SUPERFAMILY SSF53474 19 246 7.84E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24830 93c724f49687c8c8fc130ac9bd10e2a9 256 Gene3D G3DSA:3.40.50.1820 2 247 7.6E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_27850 f9eec93cf2ece81e8e4723dadbc4e250 106 Gene3D G3DSA:3.40.50.1820 5 92 4.9E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_27850 f9eec93cf2ece81e8e4723dadbc4e250 106 SUPERFAMILY SSF53474 23 89 6.13E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17645 f368cc355c2718f9eab8e305c5996865 196 Pfam PF00857 Isochorismatase family 1 181 1.5E-34 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 UA74_17645 f368cc355c2718f9eab8e305c5996865 196 SUPERFAMILY SSF52499 1 181 2.09E-36 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_17645 f368cc355c2718f9eab8e305c5996865 196 Gene3D G3DSA:3.40.50.850 1 195 3.2E-37 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_17015 b1608edff45929033f54ae091975f449 404 SUPERFAMILY SSF51338 12 402 2.44E-14 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_17015 b1608edff45929033f54ae091975f449 404 Gene3D G3DSA:3.20.20.140 64 361 7.5E-115 T 12-10-2018 UA74_17015 b1608edff45929033f54ae091975f449 404 SUPERFAMILY SSF51556 63 364 1.92E-76 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_17015 b1608edff45929033f54ae091975f449 404 Gene3D G3DSA:2.30.40.10 17 402 7.5E-115 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_17015 b1608edff45929033f54ae091975f449 404 Pfam PF01979 Amidohydrolase family 59 402 1.5E-40 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_06995 2dc0127ea8def50550f1cbf468df9003 70 Pfam PF01197 Ribosomal protein L31 2 66 4.5E-30 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_06995 2dc0127ea8def50550f1cbf468df9003 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_06995 2dc0127ea8def50550f1cbf468df9003 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 27.99 T 12-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_06995 2dc0127ea8def50550f1cbf468df9003 70 SUPERFAMILY SSF143800 2 66 8.63E-25 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_06995 2dc0127ea8def50550f1cbf468df9003 70 PRINTS PR01249 Ribosomal protein L31 signature 32 47 2.9E-21 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_06995 2dc0127ea8def50550f1cbf468df9003 70 PRINTS PR01249 Ribosomal protein L31 signature 47 65 2.9E-21 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_06995 2dc0127ea8def50550f1cbf468df9003 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.9E-21 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_06995 2dc0127ea8def50550f1cbf468df9003 70 Gene3D G3DSA:2.30.170.50 1 70 2.5E-30 T 12-10-2018 UA74_06995 2dc0127ea8def50550f1cbf468df9003 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 1.6E-31 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_05205 0ba9f6340548c0de5dbceae3e974d952 570 Gene3D G3DSA:3.30.559.10 21 215 7.2E-51 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_05205 0ba9f6340548c0de5dbceae3e974d952 570 SUPERFAMILY SSF47336 498 566 2.88E-12 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05205 0ba9f6340548c0de5dbceae3e974d952 570 SUPERFAMILY SSF52777 32 208 9.45E-44 T 12-10-2018 UA74_05205 0ba9f6340548c0de5dbceae3e974d952 570 Gene3D G3DSA:1.10.1200.10 499 570 1.7E-17 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05205 0ba9f6340548c0de5dbceae3e974d952 570 SUPERFAMILY SSF52777 215 458 5.78E-34 T 12-10-2018 UA74_05205 0ba9f6340548c0de5dbceae3e974d952 570 Gene3D G3DSA:3.30.559.30 216 460 6.2E-41 T 12-10-2018 UA74_05205 0ba9f6340548c0de5dbceae3e974d952 570 Pfam PF00668 Condensation domain 26 461 1.5E-65 T 12-10-2018 IPR001242 Condensation domain UA74_05205 0ba9f6340548c0de5dbceae3e974d952 570 Pfam PF00550 Phosphopantetheine attachment site 504 566 4.7E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 SUPERFAMILY SSF52172 3 130 5.55E-32 T 12-10-2018 IPR011006 CheY-like superfamily UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 SMART SM00421 156 213 1.1E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 3.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 3.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 3.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 213 1.5E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 Pfam PF00072 Response regulator receiver domain 5 115 5.7E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 SUPERFAMILY SSF46894 150 219 8.5E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 Gene3D G3DSA:3.40.50.12740 3 219 3.4E-66 T 12-10-2018 UA74_18120 d13d88a7bfbb320c4205dfa16641cdbd 224 SMART SM00448 3 115 3.8E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_11870 512a51c978c4dfd7d0b646d3c96c5cc0 103 Gene3D G3DSA:3.30.70.100 1 94 2.0E-14 T 12-10-2018 UA74_11870 512a51c978c4dfd7d0b646d3c96c5cc0 103 SUPERFAMILY SSF54909 1 102 2.32E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_11870 512a51c978c4dfd7d0b646d3c96c5cc0 103 Pfam PF05336 L-rhamnose mutarotase 4 91 7.0E-16 T 12-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 UA74_12295 e19df2a3c146d63216b66dd31119c816 376 Pfam PF02574 Homocysteine S-methyltransferase 23 371 1.8E-67 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UA74_12295 e19df2a3c146d63216b66dd31119c816 376 Gene3D G3DSA:3.20.20.330 13 135 4.8E-30 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UA74_12295 e19df2a3c146d63216b66dd31119c816 376 Gene3D G3DSA:3.20.20.330 143 371 1.5E-58 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UA74_12295 e19df2a3c146d63216b66dd31119c816 376 SUPERFAMILY SSF82282 19 374 1.08E-67 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UA74_12295 e19df2a3c146d63216b66dd31119c816 376 PIRSF PIRSF037505 11 131 3.2E-7 T 12-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 UA74_12295 e19df2a3c146d63216b66dd31119c816 376 PIRSF PIRSF037505 313 375 0.29 T 12-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 UA74_12295 e19df2a3c146d63216b66dd31119c816 376 PIRSF PIRSF037505 172 299 62.0 T 12-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 UA74_17905 160a68eb5ae2a3574975385f3e88d1ee 642 SUPERFAMILY SSF69322 22 362 1.31E-20 T 12-10-2018 UA74_17905 160a68eb5ae2a3574975385f3e88d1ee 642 Gene3D G3DSA:2.120.10.30 7 195 6.4E-13 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_17905 160a68eb5ae2a3574975385f3e88d1ee 642 Pfam PF00326 Prolyl oligopeptidase family 420 634 3.6E-43 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_17905 160a68eb5ae2a3574975385f3e88d1ee 642 Gene3D G3DSA:3.40.50.1820 350 639 6.0E-77 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17905 160a68eb5ae2a3574975385f3e88d1ee 642 SUPERFAMILY SSF53474 303 636 8.99E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08105 d3d70b4fda6dffde176fe9122d77db42 473 SUPERFAMILY SSF103473 16 437 3.92E-42 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_08105 d3d70b4fda6dffde176fe9122d77db42 473 Pfam PF07690 Major Facilitator Superfamily 34 389 4.7E-25 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_08105 d3d70b4fda6dffde176fe9122d77db42 473 Gene3D G3DSA:1.20.1250.20 16 431 2.1E-33 T 12-10-2018 UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Gene3D G3DSA:3.30.420.340 609 698 8.7E-21 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Gene3D G3DSA:3.30.420.340 451 540 3.4E-23 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Pfam PF02151 UvrB/uvrC motif 209 242 4.1E-10 T 12-10-2018 IPR001943 UVR domain GO:0005515 UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 756 29.569 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 SMART SM00465 17 99 3.4E-20 T 12-10-2018 IPR000305 GIY-YIG endonuclease UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 458 691 1.0E-45 T 12-10-2018 IPR001162 UvrC family homology region UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Gene3D G3DSA:4.10.860.10 206 245 3.1E-6 T 12-10-2018 UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Gene3D G3DSA:1.10.150.20 699 757 1.5E-19 T 12-10-2018 UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 SMART SM00278 705 724 20.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 SMART SM00278 737 756 27.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 SUPERFAMILY SSF82771 17 101 7.59E-22 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 SUPERFAMILY SSF46600 195 247 4.58E-14 T 12-10-2018 IPR036876 UVR domain superfamily UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 SUPERFAMILY SSF47781 650 758 3.08E-23 T 12-10-2018 IPR010994 RuvA domain 2-like UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Pfam PF14520 Helix-hairpin-helix domain 707 757 1.2E-8 T 12-10-2018 UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Pfam PF01541 GIY-YIG catalytic domain 18 92 6.7E-10 T 12-10-2018 IPR000305 GIY-YIG endonuclease UA74_12330 0b0cc35614941dc6328c46c39251ef7a 774 Gene3D G3DSA:3.40.1440.10 6 103 1.1E-28 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UA74_19020 434613aae812eb65812d5d438c06419a 409 Gene3D G3DSA:1.25.10.10 192 323 1.6E-5 T 12-10-2018 IPR011989 Armadillo-like helical UA74_19020 434613aae812eb65812d5d438c06419a 409 SUPERFAMILY SSF48371 201 400 1.41E-16 T 12-10-2018 IPR016024 Armadillo-type fold UA74_19020 434613aae812eb65812d5d438c06419a 409 SUPERFAMILY SSF160631 26 184 6.28E-11 T 12-10-2018 UA74_19020 434613aae812eb65812d5d438c06419a 409 Gene3D G3DSA:3.40.1580.10 18 88 5.1E-6 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily UA74_19020 434613aae812eb65812d5d438c06419a 409 Pfam PF13646 HEAT repeats 329 399 1.2E-8 T 12-10-2018 UA74_19020 434613aae812eb65812d5d438c06419a 409 SMART SM00567 E-Z type HEAT repeats 335 363 16.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UA74_19020 434613aae812eb65812d5d438c06419a 409 SMART SM00567 E-Z type HEAT repeats 211 242 73.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UA74_19020 434613aae812eb65812d5d438c06419a 409 SMART SM00567 E-Z type HEAT repeats 365 394 550.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UA74_19020 434613aae812eb65812d5d438c06419a 409 Gene3D G3DSA:1.25.10.110 324 409 7.4E-6 T 12-10-2018 UA74_19020 434613aae812eb65812d5d438c06419a 409 SMART SM00860 37 184 1.3E-7 T 12-10-2018 IPR018958 Knr4/Smi1-like domain UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Pfam PF00009 Elongation factor Tu GTP binding domain 15 191 2.2E-50 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Pfam PF00679 Elongation factor G C-terminus 408 494 4.7E-22 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 282.621 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Gene3D G3DSA:3.30.70.3380 378 487 1.3E-37 T 12-10-2018 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Gene3D G3DSA:3.40.50.300 12 195 3.4E-68 T 12-10-2018 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 SUPERFAMILY SSF52540 9 214 1.1E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 SMART SM00838 407 491 5.7E-4 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 185 1.7E-16 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 TIGRFAM TIGR01393 lepA: elongation factor 4 14 604 1.2E-290 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Pfam PF06421 GTP-binding protein LepA C-terminus 498 602 8.2E-49 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 SUPERFAMILY SSF50447 176 297 4.29E-24 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Gene3D G3DSA:3.30.70.870 296 377 4.3E-35 T 12-10-2018 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 60 68 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 PRINTS PR00315 GTP-binding elongation factor signature 17 30 3.2E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 SUPERFAMILY SSF54980 408 503 7.67E-23 T 12-10-2018 IPR035647 EF-G domain III/V-like UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 SUPERFAMILY SSF54980 301 380 3.2E-19 T 12-10-2018 IPR035647 EF-G domain III/V-like UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Gene3D G3DSA:3.30.70.2570 489 563 1.8E-33 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Pfam PF03144 Elongation factor Tu domain 2 215 285 2.9E-7 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UA74_08530 1c7039a19e4dd0668f2d70db6ba5af33 615 Gene3D G3DSA:2.40.30.10 196 295 2.0E-32 T 12-10-2018 UA74_05700 80e51bc650f3df57d4345f5352f32695 537 Pfam PF01494 FAD binding domain 5 355 3.0E-95 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_05700 80e51bc650f3df57d4345f5352f32695 537 SUPERFAMILY SSF51905 6 365 4.26E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_05700 80e51bc650f3df57d4345f5352f32695 537 Gene3D G3DSA:3.40.30.120 384 537 8.8E-46 T 12-10-2018 UA74_05700 80e51bc650f3df57d4345f5352f32695 537 Gene3D G3DSA:3.50.50.60 7 349 1.1E-110 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_05700 80e51bc650f3df57d4345f5352f32695 537 Gene3D G3DSA:3.30.9.50 73 287 1.1E-110 T 12-10-2018 UA74_05700 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 357 1.2E-45 T 12-10-2018 UA74_05700 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.2E-45 T 12-10-2018 UA74_05700 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 341 1.2E-45 T 12-10-2018 UA74_05700 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 162 177 1.2E-45 T 12-10-2018 UA74_05700 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 305 321 1.2E-45 T 12-10-2018 UA74_05700 80e51bc650f3df57d4345f5352f32695 537 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 305 1.2E-45 T 12-10-2018 UA74_12385 7565942cf473e86308e738484204e5e5 106 SUPERFAMILY SSF51905 2 73 6.95E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_12385 7565942cf473e86308e738484204e5e5 106 Gene3D G3DSA:3.50.50.60 6 65 1.3E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_12385 7565942cf473e86308e738484204e5e5 106 Pfam PF01494 FAD binding domain 2 66 5.3E-29 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_12385 7565942cf473e86308e738484204e5e5 106 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 41 59 7.5E-20 T 12-10-2018 UA74_12385 7565942cf473e86308e738484204e5e5 106 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 23 7.5E-20 T 12-10-2018 UA74_12385 7565942cf473e86308e738484204e5e5 106 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 23 39 7.5E-20 T 12-10-2018 UA74_03240 4bbdb3d02b716053f3332f0372d07667 217 Gene3D G3DSA:3.40.980.10 57 215 3.0E-45 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily UA74_03240 4bbdb3d02b716053f3332f0372d07667 217 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 61 200 1.8E-27 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_03240 4bbdb3d02b716053f3332f0372d07667 217 Pfam PF00994 Probable molybdopterin binding domain 64 205 1.7E-25 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_03240 4bbdb3d02b716053f3332f0372d07667 217 SMART SM00852 63 207 2.4E-17 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_03240 4bbdb3d02b716053f3332f0372d07667 217 SUPERFAMILY SSF53218 61 210 3.01E-34 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily UA74_06210 0499f61bd2ea51d9e2353fe251c535ab 341 Gene3D G3DSA:3.60.70.12 5 338 1.3E-122 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_06210 0499f61bd2ea51d9e2353fe251c535ab 341 Pfam PF03576 Peptidase family S58 11 329 3.1E-70 T 12-10-2018 IPR005321 Peptidase S58, DmpA UA74_06210 0499f61bd2ea51d9e2353fe251c535ab 341 SUPERFAMILY SSF56266 5 335 4.19E-76 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 Gene3D G3DSA:1.10.10.10 6 78 1.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.6E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.1E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.1E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 SMART SM00866 104 244 4.6E-12 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 Pfam PF07702 UTRA domain 114 242 5.6E-18 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 SMART SM00345 15 74 2.1E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 SUPERFAMILY SSF46785 4 83 7.72E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 SUPERFAMILY SSF64288 62 250 9.58E-26 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_26635 15648ad4f20da42a73d95e4bca3ed2c0 253 Gene3D G3DSA:3.40.1410.10 85 247 3.2E-28 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_02270 7ce7689ffb7c45ca3768cf413a2b1982 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 16 63 5.3E-20 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_02270 7ce7689ffb7c45ca3768cf413a2b1982 70 SUPERFAMILY SSF46955 15 63 1.48E-5 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_02270 7ce7689ffb7c45ca3768cf413a2b1982 70 Gene3D G3DSA:1.10.1660.10 14 65 1.0E-10 T 12-10-2018 UA74_02270 7ce7689ffb7c45ca3768cf413a2b1982 70 Pfam PF12728 Helix-turn-helix domain 16 64 1.4E-14 T 12-10-2018 UA74_09935 1c18b12f297915310721218e2723a0b8 153 Gene3D G3DSA:1.10.1660.10 2 131 1.4E-35 T 12-10-2018 UA74_09935 1c18b12f297915310721218e2723a0b8 153 SUPERFAMILY SSF46955 8 129 6.96E-30 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_09935 1c18b12f297915310721218e2723a0b8 153 Pfam PF00376 MerR family regulatory protein 9 45 1.4E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09935 1c18b12f297915310721218e2723a0b8 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 145 7.9E-60 T 12-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 UA74_09935 1c18b12f297915310721218e2723a0b8 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 9.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09935 1c18b12f297915310721218e2723a0b8 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 9.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09935 1c18b12f297915310721218e2723a0b8 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 9.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09935 1c18b12f297915310721218e2723a0b8 153 SMART SM00422 8 76 2.5E-24 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09935 1c18b12f297915310721218e2723a0b8 153 Pfam PF09278 MerR, DNA binding 50 115 1.6E-18 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding UA74_07895 5d5e304f7062f4d4cb2fc1d01bc3a70a 320 SUPERFAMILY SSF82689 216 313 1.31E-14 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 UA74_07895 5d5e304f7062f4d4cb2fc1d01bc3a70a 320 Gene3D G3DSA:2.30.30.60 167 216 4.2E-17 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily UA74_07895 5d5e304f7062f4d4cb2fc1d01bc3a70a 320 Pfam PF00924 Mechanosensitive ion channel 109 308 2.9E-39 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 UA74_07895 5d5e304f7062f4d4cb2fc1d01bc3a70a 320 SUPERFAMILY SSF50182 151 209 1.86E-11 T 12-10-2018 IPR010920 LSM domain superfamily UA74_07895 5d5e304f7062f4d4cb2fc1d01bc3a70a 320 Gene3D G3DSA:3.30.70.100 219 307 3.4E-22 T 12-10-2018 UA74_07895 5d5e304f7062f4d4cb2fc1d01bc3a70a 320 SUPERFAMILY SSF82861 96 150 1.26E-11 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 UA74_21630 8ce8b61ded8f83fcb53c593241aca9cc 403 Gene3D G3DSA:3.60.70.12 10 198 2.1E-68 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_21630 8ce8b61ded8f83fcb53c593241aca9cc 403 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 19 402 2.1E-114 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_21630 8ce8b61ded8f83fcb53c593241aca9cc 403 Gene3D G3DSA:3.10.20.340 278 403 2.8E-41 T 12-10-2018 UA74_21630 8ce8b61ded8f83fcb53c593241aca9cc 403 Pfam PF01960 ArgJ family 28 403 1.2E-132 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_21630 8ce8b61ded8f83fcb53c593241aca9cc 403 SUPERFAMILY SSF56266 24 399 1.44E-125 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_21630 8ce8b61ded8f83fcb53c593241aca9cc 403 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 403 132.696 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UA74_21630 8ce8b61ded8f83fcb53c593241aca9cc 403 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 48 401 9.0E-103 T 12-10-2018 UA74_21630 8ce8b61ded8f83fcb53c593241aca9cc 403 Gene3D G3DSA:3.30.2330.10 199 277 1.5E-25 T 12-10-2018 UA74_12645 2ba585281f033ebeff1066c9314a63af 130 SUPERFAMILY SSF46785 14 124 7.39E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_12645 2ba585281f033ebeff1066c9314a63af 130 Gene3D G3DSA:1.10.10.10 8 127 1.9E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12645 2ba585281f033ebeff1066c9314a63af 130 Pfam PF01638 HxlR-like helix-turn-helix 28 110 2.2E-26 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_15025 e7cee4d3580c7d3aa1b24912f54c942b 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 119 9.7E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_15025 e7cee4d3580c7d3aa1b24912f54c942b 125 Gene3D G3DSA:3.10.180.10 3 124 4.3E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_15025 e7cee4d3580c7d3aa1b24912f54c942b 125 SUPERFAMILY SSF54593 10 121 2.95E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_13945 da03ad687751661809a669b4dfd0271f 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 323 1.0E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_13945 da03ad687751661809a669b4dfd0271f 325 Gene3D G3DSA:1.10.3720.10 110 323 1.4E-21 T 12-10-2018 IPR035906 MetI-like superfamily UA74_13945 da03ad687751661809a669b4dfd0271f 325 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 49 97 7.9E-6 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_13945 da03ad687751661809a669b4dfd0271f 325 SUPERFAMILY SSF161098 116 295 3.66E-25 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22175 96048133ae9d31e52d0fe8747b02eac9 501 SMART SM00858 15 83 2.7E-14 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UA74_22175 96048133ae9d31e52d0fe8747b02eac9 501 Pfam PF08666 SAF domain 15 82 3.6E-10 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UA74_22175 96048133ae9d31e52d0fe8747b02eac9 501 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 106 499 1.7E-153 T 12-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 UA74_22175 96048133ae9d31e52d0fe8747b02eac9 501 Gene3D G3DSA:3.90.1210.30 7 84 9.2E-23 T 12-10-2018 UA74_13965 b94ae364badb7e8218faf04ca2227da0 92 Gene3D G3DSA:2.40.50.140 27 90 6.9E-31 T 12-10-2018 UA74_13965 b94ae364badb7e8218faf04ca2227da0 92 Pfam PF00313 'Cold-shock' DNA-binding domain 29 91 3.7E-29 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_13965 b94ae364badb7e8218faf04ca2227da0 92 PIRSF PIRSF002599 23 92 3.6E-25 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 UA74_13965 b94ae364badb7e8218faf04ca2227da0 92 ProSitePatterns PS00352 'Cold-shock' domain signature. 41 59 - T 12-10-2018 IPR019844 Cold-shock conserved site UA74_13965 b94ae364badb7e8218faf04ca2227da0 92 SMART SM00357 29 92 2.9E-29 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 UA74_13965 b94ae364badb7e8218faf04ca2227da0 92 SUPERFAMILY SSF50249 24 91 5.14E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_13965 b94ae364badb7e8218faf04ca2227da0 92 PRINTS PR00050 Cold shock protein signature 30 45 1.9E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_13965 b94ae364badb7e8218faf04ca2227da0 92 PRINTS PR00050 Cold shock protein signature 65 83 1.9E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_13965 b94ae364badb7e8218faf04ca2227da0 92 PRINTS PR00050 Cold shock protein signature 50 59 1.9E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_02610 50040cfb66967f8d166dc430948beb9c 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 1.0E-23 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like UA74_02610 50040cfb66967f8d166dc430948beb9c 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 20.101 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 UA74_18220 da94a25eeae130dbeb2efccb9397f7af 376 Gene3D G3DSA:3.40.50.150 6 239 1.8E-51 T 12-10-2018 UA74_18220 da94a25eeae130dbeb2efccb9397f7af 376 SUPERFAMILY SSF53335 6 207 3.31E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_18220 da94a25eeae130dbeb2efccb9397f7af 376 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 206 8.2E-30 T 12-10-2018 UA74_20445 355791600ab3957b30e4f4d9d4a25dba 335 SUPERFAMILY SSF53686 4 332 2.61E-95 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_20445 355791600ab3957b30e4f4d9d4a25dba 335 Gene3D G3DSA:3.40.50.1100 67 165 8.9E-110 T 12-10-2018 UA74_20445 355791600ab3957b30e4f4d9d4a25dba 335 Gene3D G3DSA:3.40.50.1100 16 331 8.9E-110 T 12-10-2018 UA74_20445 355791600ab3957b30e4f4d9d4a25dba 335 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 320 5.6E-43 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_20445 355791600ab3957b30e4f4d9d4a25dba 335 PIRSF PIRSF006278 1 335 1.8E-116 T 12-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase UA74_20445 355791600ab3957b30e4f4d9d4a25dba 335 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 334 2.0E-158 T 12-10-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 UA74_23390 2c93b2f650606b91c7e6db7fa97bc5e4 754 Gene3D G3DSA:3.40.50.300 436 579 5.8E-8 T 12-10-2018 UA74_23390 2c93b2f650606b91c7e6db7fa97bc5e4 754 Pfam PF13245 AAA domain 178 554 5.8E-11 T 12-10-2018 UA74_23390 2c93b2f650606b91c7e6db7fa97bc5e4 754 SUPERFAMILY SSF52540 166 736 6.37E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_23390 2c93b2f650606b91c7e6db7fa97bc5e4 754 Pfam PF13538 UvrD-like helicase C-terminal domain 684 731 3.6E-8 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain UA74_23390 2c93b2f650606b91c7e6db7fa97bc5e4 754 Gene3D G3DSA:3.40.50.300 163 319 3.5E-10 T 12-10-2018 UA74_23390 2c93b2f650606b91c7e6db7fa97bc5e4 754 Gene3D G3DSA:3.40.50.300 580 750 2.5E-15 T 12-10-2018 UA74_13655 96cfe3a0d488fc9a8aa2eb999c8f21e9 628 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_13655 96cfe3a0d488fc9a8aa2eb999c8f21e9 628 SMART SM00382 386 570 3.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13655 96cfe3a0d488fc9a8aa2eb999c8f21e9 628 Gene3D G3DSA:1.20.1560.10 3 328 6.7E-68 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13655 96cfe3a0d488fc9a8aa2eb999c8f21e9 628 SUPERFAMILY SSF52540 357 592 3.69E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13655 96cfe3a0d488fc9a8aa2eb999c8f21e9 628 SUPERFAMILY SSF90123 16 326 6.67E-60 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13655 96cfe3a0d488fc9a8aa2eb999c8f21e9 628 Pfam PF00005 ABC transporter 377 524 1.5E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13655 96cfe3a0d488fc9a8aa2eb999c8f21e9 628 Gene3D G3DSA:3.40.50.300 354 599 3.3E-75 T 12-10-2018 UA74_13655 96cfe3a0d488fc9a8aa2eb999c8f21e9 628 Pfam PF00664 ABC transporter transmembrane region 30 297 7.2E-36 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_05805 14921dc6ed78654f458566a4157673aa 921 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 891 903 2.1E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05805 14921dc6ed78654f458566a4157673aa 921 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 875 891 2.1E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05805 14921dc6ed78654f458566a4157673aa 921 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 861 875 2.1E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05805 14921dc6ed78654f458566a4157673aa 921 Gene3D G3DSA:3.40.50.300 6 192 5.2E-5 T 12-10-2018 UA74_05805 14921dc6ed78654f458566a4157673aa 921 Gene3D G3DSA:1.10.10.10 842 917 1.9E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_05805 14921dc6ed78654f458566a4157673aa 921 SUPERFAMILY SSF46894 853 913 2.82E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_05805 14921dc6ed78654f458566a4157673aa 921 SMART SM00421 858 915 2.2E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05805 14921dc6ed78654f458566a4157673aa 921 SMART SM00382 24 200 0.0037 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_05805 14921dc6ed78654f458566a4157673aa 921 ProSitePatterns PS00622 LuxR-type HTH domain signature. 875 902 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05805 14921dc6ed78654f458566a4157673aa 921 Gene3D G3DSA:1.25.40.10 571 824 1.7E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_05805 14921dc6ed78654f458566a4157673aa 921 Pfam PF00196 Bacterial regulatory proteins, luxR family 860 911 1.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05805 14921dc6ed78654f458566a4157673aa 921 SUPERFAMILY SSF52540 4 241 2.86E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_05805 14921dc6ed78654f458566a4157673aa 921 Pfam PF13191 AAA ATPase domain 7 168 1.8E-18 T 12-10-2018 UA74_17340 ab65ba0525d33758075e9293cbc3b60e 471 SUPERFAMILY SSF51556 77 383 4.66E-46 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_17340 ab65ba0525d33758075e9293cbc3b60e 471 Gene3D G3DSA:3.20.20.140 79 442 3.9E-88 T 12-10-2018 UA74_17340 ab65ba0525d33758075e9293cbc3b60e 471 SUPERFAMILY SSF51338 16 455 2.53E-22 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_17340 ab65ba0525d33758075e9293cbc3b60e 471 Pfam PF01979 Amidohydrolase family 74 428 3.3E-26 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_17340 ab65ba0525d33758075e9293cbc3b60e 471 Gene3D G3DSA:2.30.40.10 23 437 3.9E-88 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_11305 6eb7d421fe59d80b4aae5a1786bda6bc 264 Pfam PF01061 ABC-2 type transporter 20 227 3.0E-29 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_11305 6eb7d421fe59d80b4aae5a1786bda6bc 264 PIRSF PIRSF006648 1 263 2.2E-65 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_06435 bcdb978f995c5d35042f5890e2411031 260 SUPERFAMILY SSF52402 1 254 3.21E-74 T 12-10-2018 UA74_06435 bcdb978f995c5d35042f5890e2411031 260 PIRSF PIRSF000090 1 260 4.1E-84 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 UA74_06435 bcdb978f995c5d35042f5890e2411031 260 Gene3D G3DSA:3.40.50.620 1 260 1.0E-86 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_06435 bcdb978f995c5d35042f5890e2411031 260 Pfam PF01012 Electron transfer flavoprotein domain 25 208 5.1E-46 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UA74_06435 bcdb978f995c5d35042f5890e2411031 260 SMART SM00893 23 213 6.6E-54 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UA74_02105 da7dce2fbeba50f4b4ad37d1e7e17558 376 Gene3D G3DSA:3.40.50.2000 186 345 2.6E-96 T 12-10-2018 UA74_02105 da7dce2fbeba50f4b4ad37d1e7e17558 376 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 8 360 5.6E-81 T 12-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 UA74_02105 da7dce2fbeba50f4b4ad37d1e7e17558 376 Gene3D G3DSA:3.40.50.2000 10 354 2.6E-96 T 12-10-2018 UA74_02105 da7dce2fbeba50f4b4ad37d1e7e17558 376 SUPERFAMILY SSF53756 8 366 1.44E-83 T 12-10-2018 UA74_02105 da7dce2fbeba50f4b4ad37d1e7e17558 376 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 33 358 4.6E-79 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 2.7E-36 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 317 5.7E-67 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 SUPERFAMILY SSF55347 152 318 5.66E-71 T 12-10-2018 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 329 1.1E-134 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 Gene3D G3DSA:3.40.50.720 4 330 4.6E-148 T 12-10-2018 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 5.2E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 5.2E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 5.2E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 5.2E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 5.2E-41 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 SUPERFAMILY SSF51735 3 168 4.7E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 SMART SM00846 3 152 7.9E-90 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 Gene3D G3DSA:3.30.360.10 151 319 4.6E-148 T 12-10-2018 UA74_12350 0f3f0b5a8603c38fbf35eaea01a398b1 339 PIRSF PIRSF000149 1 338 5.6E-131 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 Hamap MF_00455 Xylose isomerase [xylA]. 12 391 34.678 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 14 391 1.5E-192 T 12-10-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 SUPERFAMILY SSF51658 15 395 2.49E-115 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 140 161 4.4E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 167 186 4.4E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 231 258 4.4E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 259 270 4.4E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 56 78 4.4E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 116 135 4.4E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 93 113 4.4E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 292 303 4.4E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 PRINTS PR00688 Xylose isomerase signature 189 213 4.4E-64 T 12-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 Pfam PF01261 Xylose isomerase-like TIM barrel 52 276 6.3E-25 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_27085 dbb63b6d67aa7d8d0f2d970045be8b0e 396 Gene3D G3DSA:3.20.20.150 13 395 1.5E-132 T 12-10-2018 UA74_13990 173830c8001bf373076c7fc3f8ae7e69 654 SUPERFAMILY SSF53474 385 640 1.35E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_13990 173830c8001bf373076c7fc3f8ae7e69 654 Gene3D G3DSA:3.40.50.1820 376 653 9.8E-79 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_13990 173830c8001bf373076c7fc3f8ae7e69 654 SUPERFAMILY SSF82171 79 368 3.92E-12 T 12-10-2018 UA74_13990 173830c8001bf373076c7fc3f8ae7e69 654 Pfam PF00326 Prolyl oligopeptidase family 437 641 1.9E-46 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 Pfam PF00672 HAMP domain 173 221 1.6E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 SMART SM00304 172 225 7.0E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 SUPERFAMILY SSF55874 282 448 1.01E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 448 1.1E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 291 5.7E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 SMART SM00387 333 450 9.3E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 SUPERFAMILY SSF47384 210 291 3.73E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 SUPERFAMILY SSF158472 173 222 6.67E-8 T 12-10-2018 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 9.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 401 9.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 387 9.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 Gene3D G3DSA:1.10.287.130 176 290 2.2E-24 T 12-10-2018 UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 Gene3D G3DSA:3.30.565.10 294 448 2.2E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_02665 b19bc97ae504ec1e4b5fbc07740db1f5 456 SMART SM00388 226 291 5.7E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_14330 a91f402f9aa2d6a8c6175a54b4875109 641 SUPERFAMILY SSF51445 179 506 1.05E-103 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_14330 a91f402f9aa2d6a8c6175a54b4875109 641 Gene3D G3DSA:1.20.58.460 482 635 2.0E-10 T 12-10-2018 UA74_14330 a91f402f9aa2d6a8c6175a54b4875109 641 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 39 174 5.4E-17 T 12-10-2018 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal UA74_14330 a91f402f9aa2d6a8c6175a54b4875109 641 SUPERFAMILY SSF55545 38 176 1.15E-16 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 UA74_14330 a91f402f9aa2d6a8c6175a54b4875109 641 Gene3D G3DSA:3.30.379.10 28 175 2.3E-25 T 12-10-2018 IPR029018 Beta-hexosaminidase-like, domain 2 UA74_14330 a91f402f9aa2d6a8c6175a54b4875109 641 Pfam PF07555 beta-N-acetylglucosaminidase 181 492 1.0E-107 T 12-10-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 UA74_14330 a91f402f9aa2d6a8c6175a54b4875109 641 SUPERFAMILY SSF140657 509 638 2.3E-5 T 12-10-2018 UA74_14330 a91f402f9aa2d6a8c6175a54b4875109 641 Gene3D G3DSA:3.20.20.80 176 476 5.0E-101 T 12-10-2018 UA74_24250 75447d1f5fdc9ce08edb61d9d698cccd 380 SUPERFAMILY SSF56601 21 366 1.82E-59 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_24250 75447d1f5fdc9ce08edb61d9d698cccd 380 Pfam PF00144 Beta-lactamase 26 363 8.4E-50 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_24250 75447d1f5fdc9ce08edb61d9d698cccd 380 Gene3D G3DSA:3.40.710.10 17 369 1.6E-63 T 12-10-2018 UA74_27920 40b7eda8b69f5bcc8c7c94e49bbea8eb 387 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 14 219 1.3E-27 T 12-10-2018 UA74_27920 40b7eda8b69f5bcc8c7c94e49bbea8eb 387 SUPERFAMILY SSF53335 7 213 2.29E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_27920 40b7eda8b69f5bcc8c7c94e49bbea8eb 387 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 166 181 - T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 UA74_27920 40b7eda8b69f5bcc8c7c94e49bbea8eb 387 Gene3D G3DSA:3.40.50.150 7 244 1.2E-51 T 12-10-2018 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 SUPERFAMILY SSF48264 18 400 5.5E-104 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 Gene3D G3DSA:1.10.630.10 4 401 3.6E-148 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 Pfam PF00067 Cytochrome P450 205 264 6.6E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 Pfam PF00067 Cytochrome P450 270 369 6.6E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 191 213 3.7E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 290 317 3.7E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 318 333 3.7E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 156 171 3.7E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 339 348 3.7E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 272 283 3.7E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 93 104 3.7E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 139 155 3.7E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 PRINTS PR00359 B-class P450 signature 348 359 3.7E-59 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09785 b6d84891f5e9ffd1189e25dfa7e272d2 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_04885 91339434c35fabbe0527d48989652d69 502 Pfam PF10103 Zincin-like metallopeptidase 90 438 9.3E-112 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 UA74_04885 91339434c35fabbe0527d48989652d69 502 SUPERFAMILY SSF55486 89 440 2.2E-108 T 12-10-2018 UA74_04885 91339434c35fabbe0527d48989652d69 502 Gene3D G3DSA:1.20.150.30 90 220 1.8E-6 T 12-10-2018 UA74_04885 91339434c35fabbe0527d48989652d69 502 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 90 440 9.5E-114 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 UA74_01695 dc6c74947501508c60a986e8fe12ece1 319 SUPERFAMILY SSF55315 73 149 1.29E-14 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_01695 dc6c74947501508c60a986e8fe12ece1 319 SUPERFAMILY SSF75217 140 317 4.45E-44 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_01695 dc6c74947501508c60a986e8fe12ece1 319 SMART SM00967 76 152 6.9E-17 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UA74_01695 dc6c74947501508c60a986e8fe12ece1 319 Gene3D G3DSA:3.40.1280.10 152 317 3.8E-52 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_01695 dc6c74947501508c60a986e8fe12ece1 319 Gene3D G3DSA:3.30.1330.30 51 148 7.2E-9 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_01695 dc6c74947501508c60a986e8fe12ece1 319 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 75 316 9.4E-63 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 UA74_01695 dc6c74947501508c60a986e8fe12ece1 319 Pfam PF00588 SpoU rRNA Methylase family 169 309 1.7E-35 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_01695 dc6c74947501508c60a986e8fe12ece1 319 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 77 151 1.8E-14 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UA74_30155 cf504e5ae67e4f2847b68362d828f6da 316 Gene3D G3DSA:3.40.50.2300 140 275 3.4E-88 T 12-10-2018 UA74_30155 cf504e5ae67e4f2847b68362d828f6da 316 SUPERFAMILY SSF53822 37 314 7.07E-85 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_30155 cf504e5ae67e4f2847b68362d828f6da 316 Gene3D G3DSA:3.40.50.2300 45 293 3.4E-88 T 12-10-2018 UA74_30155 cf504e5ae67e4f2847b68362d828f6da 316 Pfam PF13407 Periplasmic binding protein domain 42 293 1.0E-63 T 12-10-2018 IPR025997 Periplasmic binding protein UA74_06245 1017b069f9bd1c5226f9ecc09193508f 256 SUPERFAMILY SSF56281 3 254 4.98E-47 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_06245 1017b069f9bd1c5226f9ecc09193508f 256 SMART SM00849 18 193 3.0E-7 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_06245 1017b069f9bd1c5226f9ecc09193508f 256 Gene3D G3DSA:3.60.15.10 1 255 9.3E-68 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_06245 1017b069f9bd1c5226f9ecc09193508f 256 Pfam PF12706 Beta-lactamase superfamily domain 48 223 1.7E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_03420 07b82a70e2fa72685c0dd6da1f088325 274 Gene3D G3DSA:3.30.950.10 109 226 5.4E-40 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 UA74_03420 07b82a70e2fa72685c0dd6da1f088325 274 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 3 267 3.0E-60 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 UA74_03420 07b82a70e2fa72685c0dd6da1f088325 274 SUPERFAMILY SSF53790 2 217 7.72E-70 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 UA74_03420 07b82a70e2fa72685c0dd6da1f088325 274 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 1 219 31.071 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 UA74_03420 07b82a70e2fa72685c0dd6da1f088325 274 Gene3D G3DSA:3.40.1010.10 1 108 5.8E-29 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 UA74_03420 07b82a70e2fa72685c0dd6da1f088325 274 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 201 6.0E-26 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 UA74_03420 07b82a70e2fa72685c0dd6da1f088325 274 PIRSF PIRSF005917 1 272 4.1E-89 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 UA74_05380 4fa5de7f730049e0bf3d167905960e1d 988 Gene3D G3DSA:2.60.120.560 772 988 6.6E-73 T 12-10-2018 UA74_05380 4fa5de7f730049e0bf3d167905960e1d 988 SMART SM00758 29 169 1.5E-25 T 12-10-2018 IPR011658 PA14 domain UA74_05380 4fa5de7f730049e0bf3d167905960e1d 988 Pfam PF07691 PA14 domain 30 162 1.1E-15 T 12-10-2018 IPR011658 PA14 domain UA74_05380 4fa5de7f730049e0bf3d167905960e1d 988 SUPERFAMILY SSF101898 221 426 1.62E-10 T 12-10-2018 UA74_05380 4fa5de7f730049e0bf3d167905960e1d 988 SUPERFAMILY SSF49785 662 793 1.63E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_05380 4fa5de7f730049e0bf3d167905960e1d 988 Pfam PF06439 Domain of Unknown Function (DUF1080) 797 986 1.5E-35 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 UA74_05380 4fa5de7f730049e0bf3d167905960e1d 988 Pfam PF16990 Carbohydrate binding module (family 35) 663 793 1.3E-6 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_05380 4fa5de7f730049e0bf3d167905960e1d 988 SUPERFAMILY SSF56988 77 194 7.59E-11 T 12-10-2018 UA74_05380 4fa5de7f730049e0bf3d167905960e1d 988 Gene3D G3DSA:2.60.120.380 74 162 2.4E-8 T 12-10-2018 UA74_11615 0f08cbb0d314cb6323ae7ec73e2c5949 326 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 285 1.6E-46 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_11615 0f08cbb0d314cb6323ae7ec73e2c5949 326 Gene3D G3DSA:3.40.50.720 36 322 1.3E-89 T 12-10-2018 UA74_11615 0f08cbb0d314cb6323ae7ec73e2c5949 326 Gene3D G3DSA:3.40.50.720 103 291 1.3E-89 T 12-10-2018 UA74_11615 0f08cbb0d314cb6323ae7ec73e2c5949 326 SUPERFAMILY SSF51735 104 285 5.13E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_11615 0f08cbb0d314cb6323ae7ec73e2c5949 326 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_11615 0f08cbb0d314cb6323ae7ec73e2c5949 326 SUPERFAMILY SSF52283 39 133 4.76E-9 T 12-10-2018 UA74_04550 2c4935fd96091f852deb853b22c77fae 521 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 367 374 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_04550 2c4935fd96091f852deb853b22c77fae 521 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 204 511 1.6E-107 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_04550 2c4935fd96091f852deb853b22c77fae 521 SUPERFAMILY SSF53187 200 515 6.28E-103 T 12-10-2018 UA74_04550 2c4935fd96091f852deb853b22c77fae 521 PRINTS PR00481 Cytosol aminopeptidase signature 282 299 5.2E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_04550 2c4935fd96091f852deb853b22c77fae 521 PRINTS PR00481 Cytosol aminopeptidase signature 304 325 5.2E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_04550 2c4935fd96091f852deb853b22c77fae 521 PRINTS PR00481 Cytosol aminopeptidase signature 341 362 5.2E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_04550 2c4935fd96091f852deb853b22c77fae 521 PRINTS PR00481 Cytosol aminopeptidase signature 363 383 5.2E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_04550 2c4935fd96091f852deb853b22c77fae 521 PRINTS PR00481 Cytosol aminopeptidase signature 392 407 5.2E-47 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_04550 2c4935fd96091f852deb853b22c77fae 521 Gene3D G3DSA:3.40.630.10 185 519 1.2E-114 T 12-10-2018 UA74_17635 15912ac93d89b141fd9488886919fb71 175 Pfam PF13833 EF-hand domain pair 61 83 0.0017 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 UA74_17635 15912ac93d89b141fd9488886919fb71 175 SUPERFAMILY SSF47473 4 165 3.73E-19 T 12-10-2018 IPR011992 EF-hand domain pair UA74_17635 15912ac93d89b141fd9488886919fb71 175 ProSitePatterns PS00018 EF-hand calcium-binding domain. 67 79 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site UA74_17635 15912ac93d89b141fd9488886919fb71 175 Gene3D G3DSA:1.10.238.10 6 160 3.3E-21 T 12-10-2018 UA74_17635 15912ac93d89b141fd9488886919fb71 175 SMART SM00054 96 124 28.0 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 UA74_17635 15912ac93d89b141fd9488886919fb71 175 SMART SM00054 8 36 12.0 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 UA74_17635 15912ac93d89b141fd9488886919fb71 175 SMART SM00054 58 86 8.2 T 12-10-2018 IPR002048 EF-hand domain GO:0005509 UA74_09375 1e367679c727afa8df4f55d9c55cdcc1 461 Gene3D G3DSA:1.20.1250.20 8 228 4.5E-72 T 12-10-2018 UA74_09375 1e367679c727afa8df4f55d9c55cdcc1 461 Pfam PF07690 Major Facilitator Superfamily 57 372 6.1E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_09375 1e367679c727afa8df4f55d9c55cdcc1 461 Gene3D G3DSA:1.20.1250.20 229 450 1.1E-72 T 12-10-2018 UA74_09375 1e367679c727afa8df4f55d9c55cdcc1 461 SUPERFAMILY SSF103473 22 444 1.1E-40 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_01130 095789d7ae2e50852ec0f12afe40424b 396 SMART SM00495 42 87 5.7E-16 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_01130 095789d7ae2e50852ec0f12afe40424b 396 Gene3D G3DSA:2.10.10.20 42 85 1.3E-16 T 12-10-2018 UA74_01130 095789d7ae2e50852ec0f12afe40424b 396 SUPERFAMILY SSF51445 115 369 4.33E-20 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_01130 095789d7ae2e50852ec0f12afe40424b 396 Pfam PF02839 Carbohydrate binding domain 59 84 9.0E-5 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_01130 095789d7ae2e50852ec0f12afe40424b 396 SUPERFAMILY SSF51055 38 90 2.49E-15 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_01130 095789d7ae2e50852ec0f12afe40424b 396 Gene3D G3DSA:3.20.20.80 106 396 5.8E-82 T 12-10-2018 UA74_15995 50e71a1e705a9fc53d378a47dbd91b3c 339 SUPERFAMILY SSF48452 125 271 6.53E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_15995 50e71a1e705a9fc53d378a47dbd91b3c 339 Gene3D G3DSA:1.25.40.10 93 199 2.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_15995 50e71a1e705a9fc53d378a47dbd91b3c 339 Gene3D G3DSA:1.25.40.10 200 290 1.4E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 SUPERFAMILY SSF56655 6 259 5.76E-71 T 12-10-2018 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 3.2E-20 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 3.2E-20 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 3.2E-20 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 3.2E-20 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 Gene3D G3DSA:3.30.540.10 2 138 7.0E-42 T 12-10-2018 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 Pfam PF00459 Inositol monophosphatase family 9 235 8.8E-46 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 7 258 1.8E-84 T 12-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 UA74_26815 386991074e8d9c44e0457c58c25c8fe4 261 Gene3D G3DSA:3.40.190.80 147 259 3.4E-21 T 12-10-2018 UA74_15545 0b6ec19a96573d008db75f33f870c077 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 131 1.7E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_15545 0b6ec19a96573d008db75f33f870c077 143 SUPERFAMILY SSF54593 10 133 5.5E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_15545 0b6ec19a96573d008db75f33f870c077 143 Gene3D G3DSA:3.10.180.10 6 141 2.6E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_08920 694f4713844b1f36957d9463a8205b0a 306 SUPERFAMILY SSF47823 14 103 2.55E-11 T 12-10-2018 UA74_08920 694f4713844b1f36957d9463a8205b0a 306 Pfam PF00589 Phage integrase family 137 291 2.7E-40 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_08920 694f4713844b1f36957d9463a8205b0a 306 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 10 306 52.021 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD UA74_08920 694f4713844b1f36957d9463a8205b0a 306 SUPERFAMILY SSF56349 112 304 2.94E-46 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_08920 694f4713844b1f36957d9463a8205b0a 306 Gene3D G3DSA:1.10.150.130 11 103 4.5E-15 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_08920 694f4713844b1f36957d9463a8205b0a 306 Gene3D G3DSA:1.10.443.10 124 300 3.8E-55 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_08920 694f4713844b1f36957d9463a8205b0a 306 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 93 2.9E-15 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_26170 3c0c6901f389c62c1d3040dc8755b693 537 Pfam PF01039 Carboxyl transferase domain 50 527 4.7E-150 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 UA74_26170 3c0c6901f389c62c1d3040dc8755b693 537 SUPERFAMILY SSF52096 239 518 1.02E-88 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_26170 3c0c6901f389c62c1d3040dc8755b693 537 Gene3D G3DSA:3.90.226.10 276 537 5.9E-105 T 12-10-2018 UA74_26170 3c0c6901f389c62c1d3040dc8755b693 537 SUPERFAMILY SSF52096 26 273 1.31E-69 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_26170 3c0c6901f389c62c1d3040dc8755b693 537 Gene3D G3DSA:3.90.226.10 10 273 1.5E-94 T 12-10-2018 UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 SUPERFAMILY SSF69075 322 424 1.57E-15 T 12-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 12-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 421 25.229 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 174 310 3.0E-27 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.5E-40 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 424 5.5E-117 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 Gene3D G3DSA:3.40.50.720 162 316 3.2E-35 T 12-10-2018 UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 SUPERFAMILY SSF69742 1 158 9.68E-42 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 325 423 4.9E-20 T 12-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 SUPERFAMILY SSF51735 164 309 5.23E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_02320 716e8b1198409f5bc1a2c1d12bb24403 589 Gene3D G3DSA:3.30.460.30 1 158 1.6E-51 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UA74_01805 a8185c2129a68d7bd74fb5f81fbdaab5 480 Gene3D G3DSA:3.40.50.2000 36 471 6.3E-164 T 12-10-2018 UA74_01805 a8185c2129a68d7bd74fb5f81fbdaab5 480 SUPERFAMILY SSF53756 12 476 4.55E-143 T 12-10-2018 UA74_01805 a8185c2129a68d7bd74fb5f81fbdaab5 480 Gene3D G3DSA:3.40.50.2000 252 460 6.3E-164 T 12-10-2018 UA74_01805 a8185c2129a68d7bd74fb5f81fbdaab5 480 Pfam PF00982 Glycosyltransferase family 20 13 474 3.8E-150 T 12-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 UA74_27415 af08251a79cf2b824163f5b4e570d992 133 SUPERFAMILY SSF55298 1 133 7.38E-26 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_27415 af08251a79cf2b824163f5b4e570d992 133 Gene3D G3DSA:3.30.1330.40 4 133 1.0E-26 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_27415 af08251a79cf2b824163f5b4e570d992 133 Pfam PF01042 Endoribonuclease L-PSP 19 131 1.0E-20 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UA74_20165 92d00555624c91615c7317b90d32b787 90 Pfam PF03668 P-loop ATPase protein family 35 82 2.7E-6 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 UA74_17755 800f8a99505686b68db7e433a6c1b311 293 Gene3D G3DSA:1.10.260.40 11 89 1.3E-7 T 12-10-2018 UA74_17755 800f8a99505686b68db7e433a6c1b311 293 SMART SM00530 27 82 0.0077 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_17755 800f8a99505686b68db7e433a6c1b311 293 SUPERFAMILY SSF47413 22 80 8.16E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_17755 800f8a99505686b68db7e433a6c1b311 293 Pfam PF13560 Helix-turn-helix domain 24 83 3.2E-6 T 12-10-2018 UA74_18705 d5361253549afaf55f36d0e3faa5eb09 239 Pfam PF04909 Amidohydrolase 50 239 3.0E-29 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_18705 d5361253549afaf55f36d0e3faa5eb09 239 SUPERFAMILY SSF51556 2 239 3.74E-43 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_18705 d5361253549afaf55f36d0e3faa5eb09 239 Gene3D G3DSA:3.20.20.140 1 239 1.6E-47 T 12-10-2018 UA74_25395 2f5f05f2c869e0055094815c2861bfe1 448 Gene3D G3DSA:3.40.630.10 67 262 9.5E-36 T 12-10-2018 UA74_25395 2f5f05f2c869e0055094815c2861bfe1 448 SUPERFAMILY SSF53187 62 316 7.61E-40 T 12-10-2018 UA74_25395 2f5f05f2c869e0055094815c2861bfe1 448 SMART SM00631 64 285 2.5E-4 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_25395 2f5f05f2c869e0055094815c2861bfe1 448 Pfam PF00246 Zinc carboxypeptidase 72 194 1.8E-20 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_14165 6e7726065bdda256c80b48e2950eb0d5 239 SMART SM00418 14 91 5.6E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_14165 6e7726065bdda256c80b48e2950eb0d5 239 Gene3D G3DSA:1.10.10.10 2 95 9.4E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14165 6e7726065bdda256c80b48e2950eb0d5 239 SUPERFAMILY SSF46785 7 91 6.57E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14165 6e7726065bdda256c80b48e2950eb0d5 239 Pfam PF12840 Helix-turn-helix domain 12 71 8.8E-8 T 12-10-2018 UA74_08675 ffeb3bdbaf854409b9a4ddaa880afe0f 518 SUPERFAMILY SSF49384 412 517 1.26E-32 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UA74_08675 ffeb3bdbaf854409b9a4ddaa880afe0f 518 Gene3D G3DSA:2.60.40.290 412 518 3.6E-34 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 UA74_08675 ffeb3bdbaf854409b9a4ddaa880afe0f 518 SUPERFAMILY SSF50952 55 427 2.75E-29 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_08675 ffeb3bdbaf854409b9a4ddaa880afe0f 518 Pfam PF00553 Cellulose binding domain 417 517 1.1E-29 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_08675 ffeb3bdbaf854409b9a4ddaa880afe0f 518 Gene3D G3DSA:2.120.10.30 48 407 6.2E-88 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_08675 ffeb3bdbaf854409b9a4ddaa880afe0f 518 SMART SM00637 417 517 4.0E-40 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_08675 ffeb3bdbaf854409b9a4ddaa880afe0f 518 Pfam PF07995 Glucose / Sorbosone dehydrogenase 63 346 8.7E-47 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase UA74_20405 4b02010a5e1812cfad1372843c46cb3a 139 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 2.4E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_20405 4b02010a5e1812cfad1372843c46cb3a 139 SUPERFAMILY SSF54593 8 133 1.14E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_20405 4b02010a5e1812cfad1372843c46cb3a 139 Gene3D G3DSA:3.10.180.10 3 138 8.4E-44 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 SUPERFAMILY SSF52440 1 137 2.49E-35 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 351 38.854 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 293 321 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 Pfam PF01820 D-ala D-ala ligase N-terminus 1 127 6.8E-31 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 Pfam PF07478 D-ala D-ala ligase C-terminus 145 348 6.2E-67 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 1 350 2.3E-107 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 Gene3D G3DSA:3.40.50.20 1 126 2.2E-39 T 12-10-2018 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 Gene3D G3DSA:3.30.1490.20 153 220 2.2E-72 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 105 116 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 PIRSF PIRSF039102 1 356 2.2E-108 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 Gene3D G3DSA:3.30.470.20 127 353 2.2E-72 T 12-10-2018 UA74_25785 38b54cb5e3d7ad57e2cd7e357a68dd73 358 SUPERFAMILY SSF56059 138 352 5.56E-56 T 12-10-2018 UA74_15035 364cbb0d92336756f52ca39c2ba5d515 309 SMART SM00829 9 306 1.8E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_15035 364cbb0d92336756f52ca39c2ba5d515 309 Gene3D G3DSA:3.90.180.10 13 305 1.4E-48 T 12-10-2018 UA74_15035 364cbb0d92336756f52ca39c2ba5d515 309 Gene3D G3DSA:3.40.50.720 118 257 1.4E-48 T 12-10-2018 UA74_15035 364cbb0d92336756f52ca39c2ba5d515 309 Pfam PF13602 Zinc-binding dehydrogenase 178 306 7.2E-10 T 12-10-2018 UA74_15035 364cbb0d92336756f52ca39c2ba5d515 309 SUPERFAMILY SSF50129 11 141 4.07E-20 T 12-10-2018 IPR011032 GroES-like superfamily UA74_15035 364cbb0d92336756f52ca39c2ba5d515 309 SUPERFAMILY SSF51735 112 246 5.29E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_24270 1fbb990fc6b0f4a094f6360741891468 211 Pfam PF06445 GyrI-like small molecule binding domain 20 201 3.3E-21 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain UA74_24270 1fbb990fc6b0f4a094f6360741891468 211 PIRSF PIRSF031644 2 206 2.1E-63 T 12-10-2018 IPR008319 Uncharacterised conserved protein UCP031644 UA74_24270 1fbb990fc6b0f4a094f6360741891468 211 SUPERFAMILY SSF55136 126 195 3.14E-9 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UA74_24270 1fbb990fc6b0f4a094f6360741891468 211 Gene3D G3DSA:3.20.80.10 1 204 3.4E-79 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 Gene3D G3DSA:1.20.200.10 14 451 1.9E-139 T 12-10-2018 UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 11 452 5.3E-123 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 Gene3D G3DSA:1.10.275.60 25 234 1.9E-139 T 12-10-2018 UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 Pfam PF10397 Adenylosuccinate lyase C-terminus 370 453 1.5E-11 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 1.2E-9 T 12-10-2018 IPR000362 Fumarate lyase family UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 1.2E-9 T 12-10-2018 IPR000362 Fumarate lyase family UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 1.2E-9 T 12-10-2018 IPR000362 Fumarate lyase family UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 Pfam PF00206 Lyase 42 304 3.2E-20 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 SMART SM00998 369 455 1.3E-20 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 SUPERFAMILY SSF48557 10 456 1.52E-78 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 UA74_29285 d7563a29a557a0e10d8685bc11b6dcb5 477 Gene3D G3DSA:1.10.40.30 367 443 1.9E-139 T 12-10-2018 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 Gene3D G3DSA:3.90.190.20 316 457 1.7E-34 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 452 1.0E-106 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 Gene3D G3DSA:3.40.1190.10 93 310 1.3E-43 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 113 136 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 SUPERFAMILY SSF51984 6 93 1.57E-14 T 12-10-2018 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 SUPERFAMILY SSF53244 312 452 1.69E-33 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 9 455 30.146 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 SUPERFAMILY SSF53623 109 308 2.35E-40 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 Pfam PF08245 Mur ligase middle domain 115 226 4.3E-19 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 Gene3D G3DSA:3.40.50.720 5 92 3.4E-14 T 12-10-2018 UA74_09635 3b4bdf67380bcb7cfb538b9a87b36a0e 480 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 378 8.5E-6 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UA74_04660 e8c24045fc90bdf84edd3a3d0d634bca 360 SUPERFAMILY SSF143865 24 292 3.66E-64 T 12-10-2018 UA74_04660 e8c24045fc90bdf84edd3a3d0d634bca 360 Gene3D G3DSA:3.30.460.20 43 171 1.5E-27 T 12-10-2018 UA74_04660 e8c24045fc90bdf84edd3a3d0d634bca 360 Pfam PF01544 CorA-like Mg2+ transporter protein 63 355 1.2E-59 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 UA74_04660 e8c24045fc90bdf84edd3a3d0d634bca 360 Gene3D G3DSA:1.20.58.340 283 360 3.0E-23 T 12-10-2018 UA74_04660 e8c24045fc90bdf84edd3a3d0d634bca 360 SUPERFAMILY SSF144083 295 357 7.32E-19 T 12-10-2018 UA74_04660 e8c24045fc90bdf84edd3a3d0d634bca 360 Gene3D G3DSA:1.20.58.340 172 282 6.8E-30 T 12-10-2018 UA74_15970 0a742596da28937b41933c7e30796b3e 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 4.8E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_15970 0a742596da28937b41933c7e30796b3e 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 4.8E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_15970 0a742596da28937b41933c7e30796b3e 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 4.8E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_15970 0a742596da28937b41933c7e30796b3e 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 89 184 1.2E-16 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_15970 0a742596da28937b41933c7e30796b3e 225 Gene3D G3DSA:1.10.150.240 25 86 2.5E-47 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_15970 0a742596da28937b41933c7e30796b3e 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 184 1.8E-22 T 12-10-2018 UA74_15970 0a742596da28937b41933c7e30796b3e 225 SUPERFAMILY SSF56784 9 207 6.35E-43 T 12-10-2018 IPR036412 HAD-like superfamily UA74_15970 0a742596da28937b41933c7e30796b3e 225 Gene3D G3DSA:3.40.50.1000 11 206 2.5E-47 T 12-10-2018 IPR023214 HAD superfamily UA74_06395 160d14cae7b9adb38be1470ba65a63cd 515 SUPERFAMILY SSF88713 12 395 1.6E-93 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UA74_06395 160d14cae7b9adb38be1470ba65a63cd 515 Gene3D G3DSA:3.20.110.10 9 395 1.2E-109 T 12-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily UA74_06395 160d14cae7b9adb38be1470ba65a63cd 515 Pfam PF03065 Glycosyl hydrolase family 57 15 345 1.1E-21 T 12-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 UA74_06395 160d14cae7b9adb38be1470ba65a63cd 515 Pfam PF09210 Domain of unknown function (DUF1957) 411 505 1.4E-19 T 12-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 UA74_06395 160d14cae7b9adb38be1470ba65a63cd 515 SUPERFAMILY SSF88688 390 507 1.08E-18 T 12-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily UA74_06395 160d14cae7b9adb38be1470ba65a63cd 515 Gene3D G3DSA:1.20.1430.10 404 509 5.3E-17 T 12-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 357 489 8.5E-44 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.30.470.20 706 908 8.0E-58 T 12-10-2018 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF56059 708 910 9.06E-21 T 12-10-2018 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 SMART SM00881 208 303 1.5E-35 T 12-10-2018 IPR003781 CoA-binding GO:0048037 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Pfam PF13549 ATP-grasp domain 705 910 3.7E-52 T 12-10-2018 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.40.630.30 23 205 9.2E-47 T 12-10-2018 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF52210 496 642 9.29E-20 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF52210 334 493 7.06E-36 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.30.1490.20 724 794 8.0E-58 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Pfam PF13380 CoA binding domain 212 338 1.0E-24 T 12-10-2018 IPR003781 CoA-binding GO:0048037 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.40.50.720 206 332 4.9E-45 T 12-10-2018 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF51735 203 339 1.18E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.40.50.261 334 493 1.4E-50 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 SUPERFAMILY SSF55729 30 172 1.46E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Gene3D G3DSA:3.40.50.261 526 646 2.1E-16 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_08755 2ad2960a6883830cef9805dbc1223d1f 924 Pfam PF00583 Acetyltransferase (GNAT) family 68 166 2.6E-10 T 12-10-2018 IPR000182 GNAT domain UA74_28205 faca8703473d3ab243097c3c8cbda762 73 SMART SM00530 1 53 1.0E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_28205 faca8703473d3ab243097c3c8cbda762 73 Pfam PF01381 Helix-turn-helix 2 51 1.8E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_28205 faca8703473d3ab243097c3c8cbda762 73 Gene3D G3DSA:1.10.260.40 1 58 2.3E-18 T 12-10-2018 UA74_28205 faca8703473d3ab243097c3c8cbda762 73 SUPERFAMILY SSF47413 2 57 7.04E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_26600 89c51268fd85ca3806838739513ee402 104 Pfam PF02467 Transcription factor WhiB 36 99 2.4E-27 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain UA74_26600 89c51268fd85ca3806838739513ee402 104 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 26 104 19.382 T 12-10-2018 IPR003482 Transcription factor WhiB UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 SUPERFAMILY SSF52518 398 599 1.2E-67 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 33 595 2.6E-231 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 Gene3D G3DSA:3.40.50.970 394 603 3.0E-71 T 12-10-2018 UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 SUPERFAMILY SSF52467 216 388 6.1E-62 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 SUPERFAMILY SSF52518 28 212 1.04E-62 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 33 198 2.4E-56 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 Gene3D G3DSA:3.40.50.970 28 205 1.6E-69 T 12-10-2018 UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 222 357 2.3E-49 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 572 2.7E-49 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 Gene3D G3DSA:3.40.50.1220 217 387 1.1E-64 T 12-10-2018 UA74_25940 095aed97d3b1de0eaf3327cdfcbab475 608 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 458 477 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 Pfam PF00232 Glycosyl hydrolase family 1 18 475 8.6E-163 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 SUPERFAMILY SSF51445 20 477 7.69E-162 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 379 387 8.7E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 400 411 8.7E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 8.7E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 421 438 8.7E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 PRINTS PR00131 Glycosyl hydrolase family 1 signature 445 457 8.7E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 Gene3D G3DSA:3.20.20.80 13 477 5.7E-178 T 12-10-2018 UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 TIGRFAM TIGR03356 BGL: beta-galactosidase 21 466 3.2E-180 T 12-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 UA74_21070 259eba7d3d8ad8ebce1112648a713622 485 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 25 39 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UA74_14740 9f6bb9ee9d2f8e0b6c087be08135d8f9 447 SUPERFAMILY SSF56219 77 347 5.6E-14 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_14740 9f6bb9ee9d2f8e0b6c087be08135d8f9 447 Gene3D G3DSA:3.60.10.10 77 355 1.9E-19 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_14740 9f6bb9ee9d2f8e0b6c087be08135d8f9 447 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 82 343 1.2E-8 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase UA74_07085 7caeb22c1a58c674a3512ae203329fa7 144 Pfam PF10739 Protein of unknown function (DUF2550) 11 137 3.6E-44 T 12-10-2018 IPR019675 Protein of unknown function DUF2550 UA74_23765 6de1863652af38595ecfe52e0ebb77bd 362 SMART SM00922 142 239 1.9E-28 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_23765 6de1863652af38595ecfe52e0ebb77bd 362 SUPERFAMILY SSF54826 1 125 1.2E-24 T 12-10-2018 UA74_23765 6de1863652af38595ecfe52e0ebb77bd 362 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 23 123 4.3E-12 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_23765 6de1863652af38595ecfe52e0ebb77bd 362 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 189 220 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_23765 6de1863652af38595ecfe52e0ebb77bd 362 SUPERFAMILY SSF51604 111 357 4.85E-66 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_23765 6de1863652af38595ecfe52e0ebb77bd 362 Pfam PF13378 Enolase C-terminal domain-like 144 352 4.0E-58 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_23765 6de1863652af38595ecfe52e0ebb77bd 362 Gene3D G3DSA:3.30.390.10 14 115 1.8E-97 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_23765 6de1863652af38595ecfe52e0ebb77bd 362 Gene3D G3DSA:3.20.20.120 116 351 1.8E-97 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 290 4.8E-124 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 Pfam PF00549 CoA-ligase 158 274 4.4E-13 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 Gene3D G3DSA:3.40.50.261 130 292 2.3E-58 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 Gene3D G3DSA:3.40.50.720 1 129 1.9E-47 T 12-10-2018 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 Pfam PF02629 CoA binding domain 7 103 8.6E-27 T 12-10-2018 IPR003781 CoA-binding GO:0048037 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 SUPERFAMILY SSF52210 129 290 1.44E-44 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 PIRSF PIRSF001553 1 295 2.0E-115 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 SUPERFAMILY SSF51735 1 128 1.17E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 SMART SM00881 4 104 5.2E-33 T 12-10-2018 IPR003781 CoA-binding GO:0048037 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 5.0E-34 T 12-10-2018 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 5.0E-34 T 12-10-2018 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 5.0E-34 T 12-10-2018 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 5.0E-34 T 12-10-2018 UA74_27675 5ae79bd611fb7f2eb2fe481123dea6e8 297 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 39.15 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_16020 8d7f8c20d2d382f038a6b0b653b7242c 227 SUPERFAMILY SSF52402 14 224 3.31E-42 T 12-10-2018 UA74_16020 8d7f8c20d2d382f038a6b0b653b7242c 227 Pfam PF06508 Queuosine biosynthesis protein QueC 14 214 3.2E-42 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 UA74_16020 8d7f8c20d2d382f038a6b0b653b7242c 227 PIRSF PIRSF006293 11 227 3.7E-50 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 UA74_16020 8d7f8c20d2d382f038a6b0b653b7242c 227 Gene3D G3DSA:3.40.50.620 12 224 3.2E-47 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_24105 a99d5488ffa1ba45d607a14d4ce44bfa 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.2E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_24105 a99d5488ffa1ba45d607a14d4ce44bfa 300 Gene3D G3DSA:3.40.190.290 91 299 8.2E-35 T 12-10-2018 UA74_24105 a99d5488ffa1ba45d607a14d4ce44bfa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_24105 a99d5488ffa1ba45d607a14d4ce44bfa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_24105 a99d5488ffa1ba45d607a14d4ce44bfa 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_24105 a99d5488ffa1ba45d607a14d4ce44bfa 300 Pfam PF03466 LysR substrate binding domain 89 292 1.1E-40 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_24105 a99d5488ffa1ba45d607a14d4ce44bfa 300 SUPERFAMILY SSF53850 89 293 2.44E-38 T 12-10-2018 UA74_24105 a99d5488ffa1ba45d607a14d4ce44bfa 300 SUPERFAMILY SSF46785 1 110 7.48E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24105 a99d5488ffa1ba45d607a14d4ce44bfa 300 Gene3D G3DSA:1.10.10.10 1 86 6.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 Gene3D G3DSA:3.40.50.720 1 250 1.0E-81 T 12-10-2018 UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 6.8E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 6.8E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.8E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.8E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.8E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.8E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 3.6E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 183 0.0014 T 12-10-2018 UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 SUPERFAMILY SSF51735 5 248 3.71E-81 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 2.4E-63 T 12-10-2018 UA74_22300 e0ca7d5ad5428815fddc5a6c71ef8b66 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_03555 91c9f1262ef1f593509c8b8c93b0168d 228 SUPERFAMILY SSF161098 16 212 2.88E-38 T 12-10-2018 IPR035906 MetI-like superfamily UA74_03555 91c9f1262ef1f593509c8b8c93b0168d 228 Gene3D G3DSA:1.10.3720.10 8 222 4.0E-42 T 12-10-2018 IPR035906 MetI-like superfamily UA74_03555 91c9f1262ef1f593509c8b8c93b0168d 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 223 3.0E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00359 B-class P450 signature 87 98 9.7E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00359 B-class P450 signature 270 281 9.7E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00359 B-class P450 signature 189 211 9.7E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00359 B-class P450 signature 288 315 9.7E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00359 B-class P450 signature 134 150 9.7E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00359 B-class P450 signature 346 357 9.7E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00359 B-class P450 signature 151 166 9.7E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00359 B-class P450 signature 316 331 9.7E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00359 B-class P450 signature 337 346 9.7E-56 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 Pfam PF00067 Cytochrome P450 191 367 1.3E-26 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00385 P450 superfamily signature 337 346 6.7E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00385 P450 superfamily signature 235 252 6.7E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00385 P450 superfamily signature 346 357 6.7E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 PRINTS PR00385 P450 superfamily signature 270 281 6.7E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 Gene3D G3DSA:1.10.630.10 8 397 1.0E-118 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_08240 44d620fd699f22a6ee8d5ba986365be5 397 SUPERFAMILY SSF48264 21 397 2.1E-92 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_04605 74aa2ddae77d5cf6c9c7c39e79adf8e3 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 5.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_04605 74aa2ddae77d5cf6c9c7c39e79adf8e3 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 5.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_04605 74aa2ddae77d5cf6c9c7c39e79adf8e3 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 5.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_04605 74aa2ddae77d5cf6c9c7c39e79adf8e3 158 SUPERFAMILY SSF46785 3 134 2.73E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04605 74aa2ddae77d5cf6c9c7c39e79adf8e3 158 Gene3D G3DSA:1.10.10.10 1 139 4.7E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04605 74aa2ddae77d5cf6c9c7c39e79adf8e3 158 Pfam PF12802 MarR family 28 87 3.8E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_04605 74aa2ddae77d5cf6c9c7c39e79adf8e3 158 SMART SM00347 21 123 2.7E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_22385 12a789502f92fc3b31d30c0dcdaa2f00 193 Gene3D G3DSA:1.10.10.10 22 107 3.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22385 12a789502f92fc3b31d30c0dcdaa2f00 193 SMART SM00418 34 120 0.0015 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_22385 12a789502f92fc3b31d30c0dcdaa2f00 193 SUPERFAMILY SSF46785 36 107 2.15E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22385 12a789502f92fc3b31d30c0dcdaa2f00 193 Pfam PF12840 Helix-turn-helix domain 37 89 1.1E-12 T 12-10-2018 UA74_07760 7f7199200fdb761a1cc0448a83500743 202 Pfam PF03358 NADPH-dependent FMN reductase 5 156 1.2E-19 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_07760 7f7199200fdb761a1cc0448a83500743 202 Gene3D G3DSA:3.40.50.360 1 200 7.2E-18 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_07760 7f7199200fdb761a1cc0448a83500743 202 SUPERFAMILY SSF52218 3 198 1.1E-24 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_09875 5882999b480a8f8dec2c91a98b0e78c8 389 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 168 183 - T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 UA74_09875 5882999b480a8f8dec2c91a98b0e78c8 389 Gene3D G3DSA:3.40.50.150 12 247 2.2E-54 T 12-10-2018 UA74_09875 5882999b480a8f8dec2c91a98b0e78c8 389 SUPERFAMILY SSF53335 11 219 1.12E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_09875 5882999b480a8f8dec2c91a98b0e78c8 389 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 19 212 8.9E-29 T 12-10-2018 UA74_14145 361a428b289af976a658b9fdcd02698d 150 SUPERFAMILY SSF55729 1 140 1.47E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_14145 361a428b289af976a658b9fdcd02698d 150 Pfam PF00583 Acetyltransferase (GNAT) family 48 132 2.6E-9 T 12-10-2018 IPR000182 GNAT domain UA74_14145 361a428b289af976a658b9fdcd02698d 150 Gene3D G3DSA:3.40.630.30 1 143 1.7E-17 T 12-10-2018 UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 SUPERFAMILY SSF52518 368 579 1.0E-17 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 469 562 2.9E-6 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 427 5.0E-101 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 SUPERFAMILY SSF52518 8 184 6.42E-30 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Gene3D G3DSA:3.40.50.970 2 203 1.0E-63 T 12-10-2018 UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 181 5.2E-29 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 590 31.031 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Gene3D G3DSA:3.40.50.970 362 590 3.1E-63 T 12-10-2018 UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 Gene3D G3DSA:3.40.50.1220 207 358 1.7E-14 T 12-10-2018 UA74_02495 fb4f2c76cda9c7b4dbe97b1604ef55ad 598 PIRSF PIRSF004983 1 596 1.5E-124 T 12-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UA74_16825 23c86c6f3850465bf800b903e86874a7 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 4.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_16825 23c86c6f3850465bf800b903e86874a7 223 Gene3D G3DSA:1.10.357.10 1 171 4.5E-24 T 12-10-2018 UA74_16825 23c86c6f3850465bf800b903e86874a7 223 SUPERFAMILY SSF48498 69 136 1.4E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_16825 23c86c6f3850465bf800b903e86874a7 223 Pfam PF13305 WHG domain 78 127 1.8E-6 T 12-10-2018 IPR025996 WHG domain UA74_16825 23c86c6f3850465bf800b903e86874a7 223 SUPERFAMILY SSF46689 2 61 1.55E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_10725 980b5b1785fa43aaa992ad0536749663 633 Pfam PF07676 WD40-like Beta Propeller Repeat 156 193 5.3E-4 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_10725 980b5b1785fa43aaa992ad0536749663 633 Pfam PF07676 WD40-like Beta Propeller Repeat 72 104 2.3E-5 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_10725 980b5b1785fa43aaa992ad0536749663 633 Pfam PF07676 WD40-like Beta Propeller Repeat 33 63 0.3 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_10725 980b5b1785fa43aaa992ad0536749663 633 SUPERFAMILY SSF82171 12 346 1.1E-25 T 12-10-2018 UA74_10725 980b5b1785fa43aaa992ad0536749663 633 Gene3D G3DSA:2.120.10.30 7 126 4.4E-23 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_10725 980b5b1785fa43aaa992ad0536749663 633 SUPERFAMILY SSF53474 383 623 1.91E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_10725 980b5b1785fa43aaa992ad0536749663 633 Gene3D G3DSA:3.40.50.1820 384 626 4.5E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_10725 980b5b1785fa43aaa992ad0536749663 633 Gene3D G3DSA:2.120.10.30 127 242 1.2E-15 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_10725 980b5b1785fa43aaa992ad0536749663 633 Pfam PF00326 Prolyl oligopeptidase family 418 624 4.2E-45 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_28195 9dabb1a18e93f9d645ff46c2389d0500 335 Gene3D G3DSA:3.40.50.720 127 304 1.4E-136 T 12-10-2018 UA74_28195 9dabb1a18e93f9d645ff46c2389d0500 335 SUPERFAMILY SSF50129 6 144 1.4E-39 T 12-10-2018 IPR011032 GroES-like superfamily UA74_28195 9dabb1a18e93f9d645ff46c2389d0500 335 Pfam PF16884 N-terminal domain of oxidoreductase 7 113 2.2E-37 T 12-10-2018 UA74_28195 9dabb1a18e93f9d645ff46c2389d0500 335 SUPERFAMILY SSF51735 123 300 8.68E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_28195 9dabb1a18e93f9d645ff46c2389d0500 335 Gene3D G3DSA:3.90.180.10 22 332 1.4E-136 T 12-10-2018 UA74_28195 9dabb1a18e93f9d645ff46c2389d0500 335 SMART SM00829 19 333 2.7E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_28195 9dabb1a18e93f9d645ff46c2389d0500 335 Pfam PF00107 Zinc-binding dehydrogenase 159 286 1.1E-24 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_14805 5e70f66fe3f82040b266d13aaea77bf8 433 SUPERFAMILY SSF53383 31 426 3.98E-68 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_14805 5e70f66fe3f82040b266d13aaea77bf8 433 Pfam PF00155 Aminotransferase class I and II 71 420 8.8E-25 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_14805 5e70f66fe3f82040b266d13aaea77bf8 433 Gene3D G3DSA:3.90.1150.10 31 422 1.6E-93 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_14805 5e70f66fe3f82040b266d13aaea77bf8 433 Gene3D G3DSA:3.40.640.10 80 313 1.6E-93 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_10675 90976193fad132700277d9d8169d8114 693 Pfam PF01757 Acyltransferase family 36 366 4.5E-20 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_13070 5c6381e72ace6225c59b5f16f625d4ec 538 Gene3D G3DSA:3.40.50.300 272 512 2.1E-47 T 12-10-2018 UA74_13070 5c6381e72ace6225c59b5f16f625d4ec 538 SUPERFAMILY SSF52540 2 232 3.39E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13070 5c6381e72ace6225c59b5f16f625d4ec 538 SUPERFAMILY SSF52540 278 502 4.1E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13070 5c6381e72ace6225c59b5f16f625d4ec 538 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_13070 5c6381e72ace6225c59b5f16f625d4ec 538 SMART SM00382 27 218 3.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13070 5c6381e72ace6225c59b5f16f625d4ec 538 SMART SM00382 310 491 5.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13070 5c6381e72ace6225c59b5f16f625d4ec 538 Gene3D G3DSA:3.40.50.300 1 237 1.7E-61 T 12-10-2018 UA74_13070 5c6381e72ace6225c59b5f16f625d4ec 538 Pfam PF00005 ABC transporter 302 442 2.9E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13070 5c6381e72ace6225c59b5f16f625d4ec 538 Pfam PF00005 ABC transporter 18 169 5.6E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13620 ba076098b02d554dfdcb3d5d7bd030dc 524 Pfam PF00005 ABC transporter 44 192 3.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13620 ba076098b02d554dfdcb3d5d7bd030dc 524 Gene3D G3DSA:3.40.50.300 278 521 1.0E-40 T 12-10-2018 UA74_13620 ba076098b02d554dfdcb3d5d7bd030dc 524 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_13620 ba076098b02d554dfdcb3d5d7bd030dc 524 Pfam PF00005 ABC transporter 297 452 1.8E-15 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13620 ba076098b02d554dfdcb3d5d7bd030dc 524 SUPERFAMILY SSF52540 27 250 3.34E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13620 ba076098b02d554dfdcb3d5d7bd030dc 524 SMART SM00382 305 501 9.8 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13620 ba076098b02d554dfdcb3d5d7bd030dc 524 SMART SM00382 52 240 5.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13620 ba076098b02d554dfdcb3d5d7bd030dc 524 SUPERFAMILY SSF52540 278 512 1.9E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13620 ba076098b02d554dfdcb3d5d7bd030dc 524 Gene3D G3DSA:3.40.50.300 14 267 1.9E-57 T 12-10-2018 UA74_10975 2749cb54d8fa9eb04150e9b24a5cb280 389 Gene3D G3DSA:3.40.50.2000 199 368 1.6E-112 T 12-10-2018 UA74_10975 2749cb54d8fa9eb04150e9b24a5cb280 389 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 277 353 5.4E-10 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 UA74_10975 2749cb54d8fa9eb04150e9b24a5cb280 389 Pfam PF06722 Protein of unknown function (DUF1205) 177 269 1.3E-15 T 12-10-2018 IPR010610 Domain of unknown function DUF1205 UA74_10975 2749cb54d8fa9eb04150e9b24a5cb280 389 Gene3D G3DSA:3.40.50.11450 1 381 1.6E-112 T 12-10-2018 UA74_10975 2749cb54d8fa9eb04150e9b24a5cb280 389 SUPERFAMILY SSF53756 1 382 5.34E-68 T 12-10-2018 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 Pfam PF01336 OB-fold nucleic acid binding domain 70 146 1.4E-9 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 SUPERFAMILY SSF55681 162 501 5.77E-101 T 12-10-2018 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 Gene3D G3DSA:2.40.50.140 15 157 1.3E-35 T 12-10-2018 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 18 502 1.7E-135 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 22 503 35.336 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 Gene3D G3DSA:3.30.930.10 161 503 1.2E-112 T 12-10-2018 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 SUPERFAMILY SSF50249 16 155 6.12E-34 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 257 7.6E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 209 7.6E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 262 279 7.6E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 215 231 7.6E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 7.6E-30 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_01610 5e8b1a0d9ca3d1da02b2164f28026001 503 Pfam PF00152 tRNA synthetases class II (D, K and N) 162 500 8.2E-70 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 Gene3D G3DSA:2.40.180.10 1 482 5.8E-214 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 Pfam PF06628 Catalase-related immune-responsive 418 479 1.5E-16 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 Pfam PF00199 Catalase 8 385 3.7E-181 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 SMART SM01060 8 389 2.8E-273 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 PIRSF PIRSF038928 1 483 1.9E-229 T 12-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 104 121 1.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 123 141 1.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 320 346 1.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 288 315 1.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 21 44 1.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 PRINTS PR00067 Catalase signature 83 101 1.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_01105 be21b4446d3646eea935ff496abe6ffc 483 SUPERFAMILY SSF56634 5 481 2.62E-197 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_09340 43ad774fd39c1e2aedb7400a6025128c 311 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 18 227 5.7E-66 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_09340 43ad774fd39c1e2aedb7400a6025128c 311 SUPERFAMILY SSF88697 247 303 2.58E-12 T 12-10-2018 IPR015947 PUA-like superfamily UA74_09340 43ad774fd39c1e2aedb7400a6025128c 311 SUPERFAMILY SSF55120 17 235 3.52E-69 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_09340 43ad774fd39c1e2aedb7400a6025128c 311 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 191 231 8.3E-11 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 UA74_09340 43ad774fd39c1e2aedb7400a6025128c 311 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 247 302 3.6E-20 T 12-10-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_09340 43ad774fd39c1e2aedb7400a6025128c 311 Gene3D G3DSA:3.30.2350.10 18 238 3.6E-85 T 12-10-2018 UA74_09340 43ad774fd39c1e2aedb7400a6025128c 311 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 38 190 5.7E-50 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 UA74_09340 43ad774fd39c1e2aedb7400a6025128c 311 Gene3D G3DSA:2.30.130.10 239 301 1.2E-17 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 UA74_09340 43ad774fd39c1e2aedb7400a6025128c 311 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 16 301 16.933 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_22290 267f9450fb0e38135a03335531339471 421 Pfam PF12876 Sugar-binding cellulase-like 15 177 1.4E-12 T 12-10-2018 IPR024778 Putative cellulase UA74_22290 267f9450fb0e38135a03335531339471 421 Gene3D G3DSA:3.20.20.80 6 257 9.1E-49 T 12-10-2018 UA74_22290 267f9450fb0e38135a03335531339471 421 Gene3D G3DSA:3.20.20.80 288 421 5.3E-12 T 12-10-2018 UA74_22290 267f9450fb0e38135a03335531339471 421 SUPERFAMILY SSF51445 16 360 1.92E-13 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_02560 3341495bbe02b539e42be4aa58cd3eb4 121 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 121 17.12 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 UA74_02560 3341495bbe02b539e42be4aa58cd3eb4 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 21 120 1.9E-29 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02560 3341495bbe02b539e42be4aa58cd3eb4 121 Gene3D G3DSA:1.20.58.1610 1 121 6.7E-34 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_12180 90e8e3c611f260a65604d812a1803965 162 Gene3D G3DSA:1.10.10.1930 75 162 7.4E-34 T 12-10-2018 IPR038099 BldD-like, C-terminal domain superfamily UA74_12180 90e8e3c611f260a65604d812a1803965 162 SUPERFAMILY SSF47413 4 71 2.03E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_12180 90e8e3c611f260a65604d812a1803965 162 Pfam PF01381 Helix-turn-helix 12 68 7.4E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_12180 90e8e3c611f260a65604d812a1803965 162 Gene3D G3DSA:1.10.260.40 1 70 1.3E-32 T 12-10-2018 UA74_12180 90e8e3c611f260a65604d812a1803965 162 SMART SM00530 11 68 3.3E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 Gene3D G3DSA:1.10.101.10 84 157 9.5E-19 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 Gene3D G3DSA:1.10.101.10 1 76 5.4E-12 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 SMART SM00646 240 355 3.0E-31 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 Gene3D G3DSA:3.40.630.40 178 360 8.8E-40 T 12-10-2018 UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 SUPERFAMILY SSF47090 3 73 4.97E-12 T 12-10-2018 IPR036365 PGBD-like superfamily UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 SUPERFAMILY SSF47090 88 151 1.02E-18 T 12-10-2018 IPR036365 PGBD-like superfamily UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 Pfam PF01471 Putative peptidoglycan binding domain 94 149 2.7E-17 T 12-10-2018 IPR002477 Peptidoglycan binding-like UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 Pfam PF01471 Putative peptidoglycan binding domain 10 72 1.2E-9 T 12-10-2018 IPR002477 Peptidoglycan binding-like UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 182 355 2.4E-38 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UA74_30260 b77da52b00c81a388475ae1ee9df2635 384 SUPERFAMILY SSF53187 179 358 2.51E-43 T 12-10-2018 UA74_03835 e5cbf1388c211576804223cb5a8008d5 261 PIRSF PIRSF009160 1 261 6.8E-83 T 12-10-2018 IPR010539 Protein of unknown function UCP009160 UA74_03835 e5cbf1388c211576804223cb5a8008d5 261 Pfam PF12811 Bax inhibitor 1 like 35 260 1.1E-85 T 12-10-2018 IPR010539 Protein of unknown function UCP009160 UA74_01790 e68dc23cf3d0f20d601e5a28002f63ff 349 SMART SM00354 1 68 6.1E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_01790 e68dc23cf3d0f20d601e5a28002f63ff 349 Gene3D G3DSA:3.40.50.2300 173 301 8.1E-70 T 12-10-2018 UA74_01790 e68dc23cf3d0f20d601e5a28002f63ff 349 Pfam PF13377 Periplasmic binding protein-like domain 181 344 7.0E-38 T 12-10-2018 UA74_01790 e68dc23cf3d0f20d601e5a28002f63ff 349 Gene3D G3DSA:3.40.50.2300 54 318 8.1E-70 T 12-10-2018 UA74_01790 e68dc23cf3d0f20d601e5a28002f63ff 349 SUPERFAMILY SSF47413 3 47 2.03E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_01790 e68dc23cf3d0f20d601e5a28002f63ff 349 Gene3D G3DSA:1.10.260.40 2 45 8.1E-14 T 12-10-2018 UA74_01790 e68dc23cf3d0f20d601e5a28002f63ff 349 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 46 3.5E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_01790 e68dc23cf3d0f20d601e5a28002f63ff 349 SUPERFAMILY SSF53822 58 347 8.44E-65 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_01790 e68dc23cf3d0f20d601e5a28002f63ff 349 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 UA74_01760 3f93c589eecad623fdbeec5b4e9cbfb8 273 Pfam PF00005 ABC transporter 27 172 6.4E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_01760 3f93c589eecad623fdbeec5b4e9cbfb8 273 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_01760 3f93c589eecad623fdbeec5b4e9cbfb8 273 Gene3D G3DSA:3.40.50.300 3 259 1.2E-58 T 12-10-2018 UA74_01760 3f93c589eecad623fdbeec5b4e9cbfb8 273 SMART SM00382 35 222 1.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01760 3f93c589eecad623fdbeec5b4e9cbfb8 273 SUPERFAMILY SSF52540 10 236 1.88E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28395 6c1c7a36a74965e4b51af3f6e789eabe 303 Gene3D G3DSA:3.40.50.1000 103 198 1.2E-78 T 12-10-2018 IPR023214 HAD superfamily UA74_28395 6c1c7a36a74965e4b51af3f6e789eabe 303 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 27 247 2.1E-46 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_28395 6c1c7a36a74965e4b51af3f6e789eabe 303 Pfam PF13242 HAD-hyrolase-like 198 271 7.9E-24 T 12-10-2018 UA74_28395 6c1c7a36a74965e4b51af3f6e789eabe 303 SUPERFAMILY SSF56784 26 272 2.71E-67 T 12-10-2018 IPR036412 HAD-like superfamily UA74_28395 6c1c7a36a74965e4b51af3f6e789eabe 303 Pfam PF13344 Haloacid dehalogenase-like hydrolase 27 125 2.1E-24 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_28395 6c1c7a36a74965e4b51af3f6e789eabe 303 Gene3D G3DSA:3.40.50.1000 26 261 1.2E-78 T 12-10-2018 IPR023214 HAD superfamily UA74_28395 6c1c7a36a74965e4b51af3f6e789eabe 303 PIRSF PIRSF000915 14 276 5.7E-54 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_08375 5f13cca0e7e00b533ab2e7c8df7d63a5 307 SUPERFAMILY SSF53613 5 300 3.59E-66 T 12-10-2018 IPR029056 Ribokinase-like UA74_08375 5f13cca0e7e00b533ab2e7c8df7d63a5 307 Gene3D G3DSA:3.40.1190.20 4 304 4.3E-70 T 12-10-2018 IPR029056 Ribokinase-like UA74_08375 5f13cca0e7e00b533ab2e7c8df7d63a5 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_08375 5f13cca0e7e00b533ab2e7c8df7d63a5 307 Pfam PF00294 pfkB family carbohydrate kinase 6 300 1.9E-54 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_15570 3876bbd9eb9678d711484b7c8dbc4d7f 232 SMART SM00855 3 161 2.5E-16 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_15570 3876bbd9eb9678d711484b7c8dbc4d7f 232 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 201 3.9E-43 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_15570 3876bbd9eb9678d711484b7c8dbc4d7f 232 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 206 7.7E-96 T 12-10-2018 IPR022492 Phosphomutase MSMEG4193, putative UA74_15570 3876bbd9eb9678d711484b7c8dbc4d7f 232 Gene3D G3DSA:3.40.50.1240 1 208 5.3E-42 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_15570 3876bbd9eb9678d711484b7c8dbc4d7f 232 SUPERFAMILY SSF53254 1 200 5.57E-40 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_23780 08ed325818664b43866037d0bcf95ef5 383 Gene3D G3DSA:3.40.50.720 2 140 3.3E-34 T 12-10-2018 UA74_23780 08ed325818664b43866037d0bcf95ef5 383 SUPERFAMILY SSF55347 146 342 6.54E-29 T 12-10-2018 UA74_23780 08ed325818664b43866037d0bcf95ef5 383 Gene3D G3DSA:3.30.360.10 141 381 5.1E-64 T 12-10-2018 UA74_23780 08ed325818664b43866037d0bcf95ef5 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 138 5.6E-8 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_23780 08ed325818664b43866037d0bcf95ef5 383 SUPERFAMILY SSF51735 49 173 1.4E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_23780 08ed325818664b43866037d0bcf95ef5 383 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 152 228 3.2E-5 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UA74_19445 8a247bbfb851945d4ed2f9412b8f79ea 329 SMART SM00382 29 212 3.8E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_19445 8a247bbfb851945d4ed2f9412b8f79ea 329 Pfam PF00005 ABC transporter 20 164 9.5E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_19445 8a247bbfb851945d4ed2f9412b8f79ea 329 SUPERFAMILY SSF52540 4 225 4.24E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19445 8a247bbfb851945d4ed2f9412b8f79ea 329 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 1.4E-105 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_19445 8a247bbfb851945d4ed2f9412b8f79ea 329 Pfam PF13732 Domain of unknown function (DUF4162) 217 307 4.4E-8 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 UA74_19445 8a247bbfb851945d4ed2f9412b8f79ea 329 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_19445 8a247bbfb851945d4ed2f9412b8f79ea 329 Gene3D G3DSA:3.40.50.300 1 245 8.3E-66 T 12-10-2018 UA74_00795 51af4147f5fcf53eeed6449d9ef785ba 98 SUPERFAMILY SSF89360 1 87 3.34E-8 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UA74_00795 51af4147f5fcf53eeed6449d9ef785ba 98 Gene3D G3DSA:2.60.300.12 2 96 2.0E-7 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UA74_13240 f42dfc8a5c27d952d0a33dd550877dee 603 Gene3D G3DSA:1.20.1560.10 5 318 8.8E-42 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13240 f42dfc8a5c27d952d0a33dd550877dee 603 SUPERFAMILY SSF52540 414 599 3.25E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13240 f42dfc8a5c27d952d0a33dd550877dee 603 SUPERFAMILY SSF90123 7 319 8.11E-45 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13240 f42dfc8a5c27d952d0a33dd550877dee 603 Pfam PF00664 ABC transporter transmembrane region 28 283 6.3E-11 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_13240 f42dfc8a5c27d952d0a33dd550877dee 603 Pfam PF00005 ABC transporter 477 527 2.1E-6 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_28730 a6188e9937768f0d60d5253d3ceb3155 236 Gene3D G3DSA:2.60.120.590 9 218 2.7E-51 T 12-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily UA74_28730 a6188e9937768f0d60d5253d3ceb3155 236 SUPERFAMILY SSF51197 13 214 2.33E-44 T 12-10-2018 UA74_28730 a6188e9937768f0d60d5253d3ceb3155 236 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 15 213 2.6E-47 T 12-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like UA74_18715 cc03e46f0573344f2a06ee17041bfbc3 301 SUPERFAMILY SSF51735 1 178 1.37E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18715 cc03e46f0573344f2a06ee17041bfbc3 301 SUPERFAMILY SSF55347 141 249 1.96E-5 T 12-10-2018 UA74_18715 cc03e46f0573344f2a06ee17041bfbc3 301 Gene3D G3DSA:3.40.50.720 1 133 2.2E-12 T 12-10-2018 UA74_18715 cc03e46f0573344f2a06ee17041bfbc3 301 Gene3D G3DSA:3.30.360.10 136 260 3.0E-8 T 12-10-2018 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 689 888 1.7E-32 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.4E-66 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 SUPERFAMILY SSF52440 1 127 5.32E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Gene3D G3DSA:3.40.50.20 560 678 2.5E-44 T 12-10-2018 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1077 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 725 739 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Gene3D G3DSA:1.10.1030.10 410 555 1.2E-36 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 SUPERFAMILY SSF52440 563 690 8.34E-42 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Gene3D G3DSA:3.30.470.20 120 402 1.5E-118 T 12-10-2018 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Gene3D G3DSA:3.40.50.20 1 116 1.2E-47 T 12-10-2018 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 854 861 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 SMART SM01096 426 549 4.1E-56 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 1.1E-35 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 SUPERFAMILY SSF56059 128 400 1.77E-101 T 12-10-2018 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 5.3E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 5.3E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 5.3E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 5.3E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 5.3E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 5.3E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 5.3E-62 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 SUPERFAMILY SSF48108 396 553 5.75E-40 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Gene3D G3DSA:3.40.50.1380 967 1091 5.1E-6 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 SUPERFAMILY SSF56059 689 964 4.95E-93 T 12-10-2018 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1087 12.541 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 SUPERFAMILY SSF52335 966 1097 7.78E-5 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UA74_17150 aeeb5c9bbb7be17434f3a8306fc9a336 1137 Gene3D G3DSA:3.30.470.20 681 966 4.7E-103 T 12-10-2018 UA74_13190 70dbab951a075bb3d13088ee4747f655 855 SUPERFAMILY SSF56112 225 428 9.98E-20 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_13190 70dbab951a075bb3d13088ee4747f655 855 Pfam PF01636 Phosphotransferase enzyme family 282 387 1.1E-6 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_13190 70dbab951a075bb3d13088ee4747f655 855 Gene3D G3DSA:1.10.510.10 313 423 2.7E-13 T 12-10-2018 UA74_13190 70dbab951a075bb3d13088ee4747f655 855 Gene3D G3DSA:3.30.200.20 225 312 2.7E-13 T 12-10-2018 UA74_13190 70dbab951a075bb3d13088ee4747f655 855 SMART SM01260 521 849 5.7E-9 T 12-10-2018 IPR007822 Lanthionine synthetase C-like UA74_13190 70dbab951a075bb3d13088ee4747f655 855 SUPERFAMILY SSF158745 514 843 7.85E-24 T 12-10-2018 UA74_13190 70dbab951a075bb3d13088ee4747f655 855 SMART SM00220 226 513 0.0024 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 Gene3D G3DSA:3.30.460.10 234 366 2.2E-45 T 12-10-2018 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 Pfam PF04607 Region found in RelA / SpoT proteins 276 385 1.9E-36 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 Gene3D G3DSA:3.30.70.260 690 770 1.6E-16 T 12-10-2018 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 Gene3D G3DSA:3.10.20.30 426 497 1.5E-32 T 12-10-2018 IPR012675 Beta-grasp domain superfamily UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 SUPERFAMILY SSF109604 45 231 1.15E-69 T 12-10-2018 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 SMART SM00954 276 386 1.6E-61 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 Pfam PF13328 HD domain 69 216 7.7E-48 T 12-10-2018 IPR003607 HD/PDEase domain UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 SUPERFAMILY SSF81301 233 410 1.14E-60 T 12-10-2018 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 Pfam PF13291 ACT domain 690 766 2.2E-16 T 12-10-2018 IPR002912 ACT domain UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 SUPERFAMILY SSF81271 420 492 4.58E-23 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 69 766 3.0E-264 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 Pfam PF02824 TGS domain 433 492 1.0E-23 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 SMART SM00471 84 194 2.2E-12 T 12-10-2018 IPR003607 HD/PDEase domain UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 Gene3D G3DSA:1.10.3210.10 40 232 7.7E-78 T 12-10-2018 UA74_11095 15b13ddb45d099a68fdb1030fcb6e056 771 SUPERFAMILY SSF55021 690 769 2.25E-14 T 12-10-2018 UA74_29200 8543f1a409dbe03b82ae32e502820741 474 PRINTS PR01228 Eggshell protein signature 376 391 8.8E-5 T 12-10-2018 UA74_29200 8543f1a409dbe03b82ae32e502820741 474 PRINTS PR01228 Eggshell protein signature 428 446 8.8E-5 T 12-10-2018 UA74_29200 8543f1a409dbe03b82ae32e502820741 474 PRINTS PR01228 Eggshell protein signature 312 323 8.8E-5 T 12-10-2018 UA74_29200 8543f1a409dbe03b82ae32e502820741 474 PRINTS PR01228 Eggshell protein signature 404 414 8.8E-5 T 12-10-2018 UA74_29200 8543f1a409dbe03b82ae32e502820741 474 SUPERFAMILY SSF140459 32 178 2.28E-7 T 12-10-2018 UA74_20650 0f7ce87853c8c2fa255604d7d913f9c7 476 SUPERFAMILY SSF100950 69 299 7.11E-35 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_20650 0f7ce87853c8c2fa255604d7d913f9c7 476 Gene3D G3DSA:3.40.50.10420 135 284 4.1E-9 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily UA74_20650 0f7ce87853c8c2fa255604d7d913f9c7 476 Pfam PF11870 Domain of unknown function (DUF3390) 400 473 1.2E-6 T 12-10-2018 IPR024569 4Fe-4S binding protein, C-terminal UA74_20650 0f7ce87853c8c2fa255604d7d913f9c7 476 SUPERFAMILY SSF54862 295 399 2.85E-15 T 12-10-2018 UA74_20650 0f7ce87853c8c2fa255604d7d913f9c7 476 Gene3D G3DSA:1.10.1060.10 300 403 1.1E-5 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_20650 0f7ce87853c8c2fa255604d7d913f9c7 476 Pfam PF13183 4Fe-4S dicluster domain 314 384 6.7E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_20650 0f7ce87853c8c2fa255604d7d913f9c7 476 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 23 460 7.1E-137 T 12-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 UA74_20650 0f7ce87853c8c2fa255604d7d913f9c7 476 Pfam PF02589 LUD domain 74 297 3.0E-47 T 12-10-2018 IPR003741 LUD domain UA74_20650 0f7ce87853c8c2fa255604d7d913f9c7 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 317 328 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_10940 daccf22ac9c98b3bf9af253efb45a749 715 Gene3D G3DSA:3.30.410.10 125 437 4.1E-85 T 12-10-2018 UA74_10940 daccf22ac9c98b3bf9af253efb45a749 715 Pfam PF00732 GMC oxidoreductase 184 272 8.0E-8 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_10940 daccf22ac9c98b3bf9af253efb45a749 715 SUPERFAMILY SSF51905 6 504 4.49E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10940 daccf22ac9c98b3bf9af253efb45a749 715 Gene3D G3DSA:3.50.50.60 9 502 4.1E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10940 daccf22ac9c98b3bf9af253efb45a749 715 Pfam PF13450 NAD(P)-binding Rossmann-like domain 11 40 9.4E-6 T 12-10-2018 UA74_10940 daccf22ac9c98b3bf9af253efb45a749 715 Pfam PF05199 GMC oxidoreductase 439 496 2.0E-16 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 UA74_28120 a24085bd72a7dfd5a7b9475a5c932cb1 274 Gene3D G3DSA:3.10.180.10 7 127 6.2E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_28120 a24085bd72a7dfd5a7b9475a5c932cb1 274 Gene3D G3DSA:3.10.180.10 133 259 1.5E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_28120 a24085bd72a7dfd5a7b9475a5c932cb1 274 SUPERFAMILY SSF54593 12 121 2.0E-7 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_28120 a24085bd72a7dfd5a7b9475a5c932cb1 274 SUPERFAMILY SSF54593 139 256 3.16E-14 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_00770 82550732c50ed727141407adb39c8f0e 260 SUPERFAMILY SSF46785 9 90 7.52E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_00770 82550732c50ed727141407adb39c8f0e 260 SMART SM00345 20 79 2.0E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_00770 82550732c50ed727141407adb39c8f0e 260 Pfam PF07702 UTRA domain 112 251 2.3E-29 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_00770 82550732c50ed727141407adb39c8f0e 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 9.5E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_00770 82550732c50ed727141407adb39c8f0e 260 SMART SM00866 111 252 9.6E-25 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_00770 82550732c50ed727141407adb39c8f0e 260 Gene3D G3DSA:1.10.10.10 7 80 9.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_00770 82550732c50ed727141407adb39c8f0e 260 SUPERFAMILY SSF64288 67 257 5.23E-37 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_00770 82550732c50ed727141407adb39c8f0e 260 Gene3D G3DSA:3.40.1410.10 86 255 2.0E-47 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_00770 82550732c50ed727141407adb39c8f0e 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_00770 82550732c50ed727141407adb39c8f0e 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 Pfam PF01595 Domain of unknown function DUF21 23 207 7.3E-42 T 12-10-2018 IPR002550 CNNM, transmembrane domain UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 Gene3D G3DSA:3.30.465.10 369 440 9.3E-19 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 SUPERFAMILY SSF56176 366 445 4.64E-19 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 Pfam PF00571 CBS domain 312 347 1.8E-4 T 12-10-2018 IPR000644 CBS domain UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 Pfam PF00571 CBS domain 232 284 2.2E-4 T 12-10-2018 IPR000644 CBS domain UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 SMART SM01091 362 440 4.6E-21 T 12-10-2018 IPR005170 Transporter-associated domain UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 SMART SM00116 236 285 0.3 T 12-10-2018 IPR000644 CBS domain UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 SMART SM00116 299 347 7.1 T 12-10-2018 IPR000644 CBS domain UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 Pfam PF03471 Transporter associated domain 365 439 6.4E-20 T 12-10-2018 IPR005170 Transporter-associated domain UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 SUPERFAMILY SSF54631 224 357 2.27E-28 T 12-10-2018 UA74_26090 f6b9aebf584a72d3b6673881147db3ea 469 Gene3D G3DSA:3.10.580.10 208 360 1.9E-45 T 12-10-2018 UA74_10810 bc4ce5e9bece0e52c55c1d96a2587314 188 Gene3D G3DSA:1.10.260.40 2 83 1.9E-17 T 12-10-2018 UA74_10810 bc4ce5e9bece0e52c55c1d96a2587314 188 SUPERFAMILY SSF51182 65 185 4.69E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_10810 bc4ce5e9bece0e52c55c1d96a2587314 188 SMART SM00530 17 72 1.6E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_10810 bc4ce5e9bece0e52c55c1d96a2587314 188 Gene3D G3DSA:2.60.120.10 101 188 6.0E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_10810 bc4ce5e9bece0e52c55c1d96a2587314 188 SUPERFAMILY SSF47413 13 78 2.0E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_10810 bc4ce5e9bece0e52c55c1d96a2587314 188 Pfam PF01381 Helix-turn-helix 18 70 5.4E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_06770 4126bb62494d943de713efbbf3b38060 249 PIRSF PIRSF001060 8 249 3.6E-80 T 12-10-2018 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 UA74_06770 4126bb62494d943de713efbbf3b38060 249 Gene3D G3DSA:1.10.530.70 45 240 1.7E-81 T 12-10-2018 UA74_06770 4126bb62494d943de713efbbf3b38060 249 Pfam PF00182 Chitinase class I 47 249 2.5E-43 T 12-10-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 UA74_06770 4126bb62494d943de713efbbf3b38060 249 SUPERFAMILY SSF53955 45 249 3.66E-65 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_18140 0e6191ebeae5383b041140a61636a846 216 SUPERFAMILY SSF55961 21 162 2.58E-32 T 12-10-2018 UA74_18140 0e6191ebeae5383b041140a61636a846 216 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 36 147 3.8E-16 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_18140 0e6191ebeae5383b041140a61636a846 216 Gene3D G3DSA:3.30.530.20 7 191 2.1E-44 T 12-10-2018 IPR023393 START-like domain superfamily UA74_01125 48b45853dc32cf0a5f7b3d3128aaea3d 163 Pfam PF00210 Ferritin-like domain 25 162 2.9E-20 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 UA74_01125 48b45853dc32cf0a5f7b3d3128aaea3d 163 PIRSF PIRSF005900 1 163 1.3E-40 T 12-10-2018 IPR002177 DNA-binding protein Dps UA74_01125 48b45853dc32cf0a5f7b3d3128aaea3d 163 Gene3D G3DSA:1.20.1260.10 2 163 9.7E-41 T 12-10-2018 IPR012347 Ferritin-like UA74_01125 48b45853dc32cf0a5f7b3d3128aaea3d 163 SUPERFAMILY SSF47240 11 159 1.89E-40 T 12-10-2018 IPR009078 Ferritin-like superfamily UA74_01125 48b45853dc32cf0a5f7b3d3128aaea3d 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 139 157 2.4E-11 T 12-10-2018 IPR002177 DNA-binding protein Dps UA74_01125 48b45853dc32cf0a5f7b3d3128aaea3d 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 44 60 2.4E-11 T 12-10-2018 IPR002177 DNA-binding protein Dps UA74_01125 48b45853dc32cf0a5f7b3d3128aaea3d 163 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 68 84 2.4E-11 T 12-10-2018 IPR002177 DNA-binding protein Dps UA74_08870 3ff4be7c93196cf1be90750ba5b2987c 552 Gene3D G3DSA:3.10.105.10 274 512 2.2E-155 T 12-10-2018 UA74_08870 3ff4be7c93196cf1be90750ba5b2987c 552 SUPERFAMILY SSF53850 46 527 8.15E-103 T 12-10-2018 UA74_08870 3ff4be7c93196cf1be90750ba5b2987c 552 Gene3D G3DSA:3.90.76.10 70 175 2.2E-155 T 12-10-2018 UA74_08870 3ff4be7c93196cf1be90750ba5b2987c 552 Gene3D G3DSA:3.40.190.10 52 536 2.2E-155 T 12-10-2018 UA74_08870 3ff4be7c93196cf1be90750ba5b2987c 552 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 445 8.6E-74 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_08870 3ff4be7c93196cf1be90750ba5b2987c 552 PIRSF PIRSF002741 5 531 4.5E-83 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_15420 4c605cebef1e23c7a21cbd25fae4312b 199 SUPERFAMILY SSF55961 22 160 6.25E-28 T 12-10-2018 UA74_15420 4c605cebef1e23c7a21cbd25fae4312b 199 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 36 153 6.2E-12 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_15420 4c605cebef1e23c7a21cbd25fae4312b 199 Gene3D G3DSA:3.30.530.20 11 195 2.0E-38 T 12-10-2018 IPR023393 START-like domain superfamily UA74_18315 819e0586844c64c67b35d4c45e998fe6 376 Pfam PF02653 Branched-chain amino acid transport system / permease component 97 355 9.4E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 47 214 3.1E-31 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 SMART SM00479 51 219 2.7E-47 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 Pfam PF02151 UvrB/uvrC motif 439 469 6.3E-5 T 12-10-2018 IPR001943 UVR domain GO:0005515 UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 Gene3D G3DSA:3.30.420.10 47 217 1.3E-49 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 SUPERFAMILY SSF53098 46 229 1.21E-54 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 SMART SM00465 252 333 1.7E-10 T 12-10-2018 IPR000305 GIY-YIG endonuclease UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 Gene3D G3DSA:3.40.1440.10 238 335 3.5E-22 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 Pfam PF00929 Exonuclease 53 210 6.2E-34 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 Pfam PF01541 GIY-YIG catalytic domain 254 328 7.7E-5 T 12-10-2018 IPR000305 GIY-YIG endonuclease UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 SUPERFAMILY SSF82771 252 330 9.94E-14 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UA74_24895 596af766abbc64a88b48eb7661acfbb3 599 SUPERFAMILY SSF46600 428 470 7.72E-6 T 12-10-2018 IPR036876 UVR domain superfamily UA74_11825 44a5b9c3023efdf42ba01cf3da625fa8 225 Pfam PF06283 Trehalose utilisation 10 220 8.5E-73 T 12-10-2018 IPR029010 ThuA-like domain UA74_11825 44a5b9c3023efdf42ba01cf3da625fa8 225 Gene3D G3DSA:3.40.50.880 1 224 4.5E-81 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_11825 44a5b9c3023efdf42ba01cf3da625fa8 225 SUPERFAMILY SSF52317 7 222 1.24E-43 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_26910 01c1996ed90b185c37bf450faa8e34f3 364 Gene3D G3DSA:2.40.50.140 255 357 2.3E-6 T 12-10-2018 UA74_26910 01c1996ed90b185c37bf450faa8e34f3 364 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_26910 01c1996ed90b185c37bf450faa8e34f3 364 Pfam PF08402 TOBE domain 283 358 1.7E-13 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 UA74_26910 01c1996ed90b185c37bf450faa8e34f3 364 SMART SM00382 27 216 3.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_26910 01c1996ed90b185c37bf450faa8e34f3 364 Pfam PF00005 ABC transporter 19 166 6.3E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_26910 01c1996ed90b185c37bf450faa8e34f3 364 Gene3D G3DSA:3.40.50.300 1 243 1.4E-70 T 12-10-2018 UA74_26910 01c1996ed90b185c37bf450faa8e34f3 364 SUPERFAMILY SSF50331 243 358 3.4E-10 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UA74_26910 01c1996ed90b185c37bf450faa8e34f3 364 Gene3D G3DSA:2.40.50.100 285 353 2.3E-6 T 12-10-2018 UA74_26910 01c1996ed90b185c37bf450faa8e34f3 364 SUPERFAMILY SSF52540 3 245 8.57E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24860 17b74616ef189e7e50fa8fe605b5c2dc 261 SUPERFAMILY SSF56300 2 254 6.84E-29 T 12-10-2018 UA74_24860 17b74616ef189e7e50fa8fe605b5c2dc 261 Pfam PF00149 Calcineurin-like phosphoesterase 2 232 3.8E-7 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UA74_12060 806d2a706ef68bd2977b45bd0b53c047 287 Gene3D G3DSA:3.40.50.10860 10 267 1.2E-73 T 12-10-2018 UA74_12060 806d2a706ef68bd2977b45bd0b53c047 287 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 5 274 2.3E-70 T 12-10-2018 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+1.1.1.25+4.2.1.10+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_12060 806d2a706ef68bd2977b45bd0b53c047 287 Gene3D G3DSA:3.40.50.720 107 252 1.2E-73 T 12-10-2018 UA74_12060 806d2a706ef68bd2977b45bd0b53c047 287 SUPERFAMILY SSF53223 4 106 1.67E-22 T 12-10-2018 UA74_12060 806d2a706ef68bd2977b45bd0b53c047 287 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 11 93 1.6E-19 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 UA74_12060 806d2a706ef68bd2977b45bd0b53c047 287 SUPERFAMILY SSF51735 107 277 1.17E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_01565 1bed4be1fc9ca05f9bca97998dd1483a 166 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 130 7.4E-34 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UA74_01565 1bed4be1fc9ca05f9bca97998dd1483a 166 Gene3D G3DSA:3.30.70.560 1 155 1.4E-41 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UA74_01565 1bed4be1fc9ca05f9bca97998dd1483a 166 SUPERFAMILY SSF55083 1 151 9.81E-43 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UA74_01565 1bed4be1fc9ca05f9bca97998dd1483a 166 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 85 96 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UA74_01565 1bed4be1fc9ca05f9bca97998dd1483a 166 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 130 2.8E-29 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 Pfam PF00561 alpha/beta hydrolase fold 37 299 1.0E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 SUPERFAMILY SSF53474 14 314 7.19E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 4.9E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 4.9E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 4.9E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 63 78 4.1E-24 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 43 61 4.1E-24 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 121 134 4.1E-24 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 290 312 4.1E-24 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 PRINTS PR00412 Epoxide hydrolase signature 107 120 4.1E-24 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_01280 f12b56cdbc7f2d1c1df8e40b798a2f95 319 Gene3D G3DSA:3.40.50.1820 16 314 2.0E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18725 ad16b06ee71c6a65f7025daa5b7274f6 296 Gene3D G3DSA:1.10.3720.10 57 294 8.0E-70 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18725 ad16b06ee71c6a65f7025daa5b7274f6 296 SUPERFAMILY SSF161098 63 287 3.92E-61 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18725 ad16b06ee71c6a65f7025daa5b7274f6 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 289 2.8E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_06450 95a9ee7feaa132b52d693977fd511242 365 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 2 362 35.891 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 UA74_06450 95a9ee7feaa132b52d693977fd511242 365 Gene3D G3DSA:2.30.30.280 214 279 8.5E-10 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 UA74_06450 95a9ee7feaa132b52d693977fd511242 365 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 3 360 1.9E-84 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 UA74_06450 95a9ee7feaa132b52d693977fd511242 365 Gene3D G3DSA:2.40.30.10 280 365 3.1E-10 T 12-10-2018 UA74_06450 95a9ee7feaa132b52d693977fd511242 365 SUPERFAMILY SSF52402 3 245 2.65E-45 T 12-10-2018 UA74_06450 95a9ee7feaa132b52d693977fd511242 365 Gene3D G3DSA:3.40.50.620 1 212 7.8E-73 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_06450 95a9ee7feaa132b52d693977fd511242 365 Pfam PF03054 tRNA methyl transferase 3 360 3.8E-112 T 12-10-2018 UA74_05635 b9b4d636fd0600e1be7038ac9302bf29 488 Gene3D G3DSA:3.30.200.20 4 98 6.8E-27 T 12-10-2018 UA74_05635 b9b4d636fd0600e1be7038ac9302bf29 488 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 139 151 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_05635 b9b4d636fd0600e1be7038ac9302bf29 488 Pfam PF00069 Protein kinase domain 17 268 3.9E-46 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_05635 b9b4d636fd0600e1be7038ac9302bf29 488 SMART SM00220 15 274 1.2E-55 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_05635 b9b4d636fd0600e1be7038ac9302bf29 488 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_05635 b9b4d636fd0600e1be7038ac9302bf29 488 SUPERFAMILY SSF56112 8 268 4.45E-68 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_05635 b9b4d636fd0600e1be7038ac9302bf29 488 Gene3D G3DSA:1.10.510.10 101 274 4.3E-43 T 12-10-2018 UA74_25595 ab8135194df00a913af30b80a5b8e39e 60 SUPERFAMILY SSF57829 2 56 1.22E-19 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 UA74_25595 ab8135194df00a913af30b80a5b8e39e 60 Pfam PF01783 Ribosomal L32p protein family 2 56 3.3E-26 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_25595 ab8135194df00a913af30b80a5b8e39e 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 2.6E-25 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_25595 ab8135194df00a913af30b80a5b8e39e 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 57 18.467 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_00440 687d77ed716df186d323b8004083aed3 301 SUPERFAMILY SSF52096 23 238 2.89E-39 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_00440 687d77ed716df186d323b8004083aed3 301 Gene3D G3DSA:3.40.1750.20 140 206 1.3E-55 T 12-10-2018 UA74_00440 687d77ed716df186d323b8004083aed3 301 Pfam PF01343 Peptidase family S49 104 244 9.1E-33 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 UA74_00440 687d77ed716df186d323b8004083aed3 301 Gene3D G3DSA:3.90.226.10 29 242 1.3E-55 T 12-10-2018 UA74_18240 14419017dcf69e57eaf3d666c2538787 507 Gene3D G3DSA:3.40.50.300 280 493 2.4E-37 T 12-10-2018 UA74_18240 14419017dcf69e57eaf3d666c2538787 507 SUPERFAMILY SSF52540 16 240 1.48E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18240 14419017dcf69e57eaf3d666c2538787 507 Gene3D G3DSA:3.40.50.300 12 257 6.2E-55 T 12-10-2018 UA74_18240 14419017dcf69e57eaf3d666c2538787 507 SMART SM00382 41 238 4.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_18240 14419017dcf69e57eaf3d666c2538787 507 SMART SM00382 292 484 2.5 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_18240 14419017dcf69e57eaf3d666c2538787 507 Pfam PF00005 ABC transporter 32 182 1.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_18240 14419017dcf69e57eaf3d666c2538787 507 SUPERFAMILY SSF52540 284 490 8.78E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18240 14419017dcf69e57eaf3d666c2538787 507 Pfam PF00005 ABC transporter 285 437 1.1E-14 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 SUPERFAMILY SSF53901 5 270 4.95E-83 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 Pfam PF00108 Thiolase, N-terminal domain 5 262 3.6E-98 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 PIRSF PIRSF000429 2 394 1.1E-111 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 Gene3D G3DSA:3.40.47.10 126 389 8.3E-137 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 SUPERFAMILY SSF53901 272 390 4.94E-34 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 3.7E-130 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 Pfam PF02803 Thiolase, C-terminal domain 271 391 9.5E-39 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UA74_07195 5293b39c29ea8317ddc4336e80e2a180 395 Gene3D G3DSA:3.40.47.10 5 276 8.3E-137 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 SUPERFAMILY SSF52777 617 780 2.78E-41 T 12-10-2018 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 495 2.6E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 SUPERFAMILY SSF56801 7 539 1.96E-129 T 12-10-2018 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:3.40.50.12780 2 410 3.6E-114 T 12-10-2018 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 SMART SM00823 Phosphopantetheine attachment site 526 595 0.0065 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:3.30.559.30 784 1031 6.3E-111 T 12-10-2018 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:3.30.559.10 615 975 6.3E-111 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:3.30.300.30 413 513 1.3E-26 T 12-10-2018 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 33 442 1.7E-106 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 SUPERFAMILY SSF47336 521 625 1.22E-12 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 SUPERFAMILY SSF52777 786 1033 1.89E-44 T 12-10-2018 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 Pfam PF00501 AMP-binding enzyme 13 418 8.2E-80 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 Gene3D G3DSA:1.10.1200.10 514 596 3.8E-14 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 Pfam PF00668 Condensation domain 614 1034 1.3E-76 T 12-10-2018 IPR001242 Condensation domain UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 Pfam PF00550 Phosphopantetheine attachment site 528 589 3.9E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_05160 bbd2b6fd738c157dd98dc595ebd6173b 1050 ProSitePatterns PS00012 Phosphopantetheine attachment site. 550 565 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16660 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:3.40.50.300 13 442 3.5E-145 T 12-10-2018 UA74_16660 17f3872bac8e89b8176284197f52274c 769 SUPERFAMILY SSF52540 471 735 4.23E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16660 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:1.20.1580.10 550 588 4.0E-94 T 12-10-2018 UA74_16660 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:3.40.50.300 468 757 4.0E-94 T 12-10-2018 UA74_16660 17f3872bac8e89b8176284197f52274c 769 SUPERFAMILY SSF52540 12 424 6.54E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16660 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:1.10.8.280 152 264 3.5E-145 T 12-10-2018 UA74_16660 17f3872bac8e89b8176284197f52274c 769 SMART SM00382 482 729 0.2 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_16660 17f3872bac8e89b8176284197f52274c 769 SMART SM00382 30 419 1.1 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_16660 17f3872bac8e89b8176284197f52274c 769 Gene3D G3DSA:1.20.1580.10 98 342 3.5E-145 T 12-10-2018 UA74_23855 91c68754892535cb02de637f6fe9b52e 393 SUPERFAMILY SSF51658 30 367 1.13E-90 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_23855 91c68754892535cb02de637f6fe9b52e 393 Gene3D G3DSA:3.20.20.150 8 385 3.1E-130 T 12-10-2018 UA74_23855 91c68754892535cb02de637f6fe9b52e 393 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 12 383 1.3E-189 T 12-10-2018 IPR013457 Rhamnose isomerase-related UA74_23855 91c68754892535cb02de637f6fe9b52e 393 Pfam PF06134 L-rhamnose isomerase (RhaA) 96 341 2.8E-6 T 12-10-2018 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 UA74_23855 91c68754892535cb02de637f6fe9b52e 393 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 110 332 2.0E-7 T 12-10-2018 UA74_27600 6b7f8d12962ddeb6e8a376a41b370572 338 Pfam PF04657 Putative inner membrane exporter, YdcZ 195 329 5.6E-19 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ UA74_27600 6b7f8d12962ddeb6e8a376a41b370572 338 Pfam PF04657 Putative inner membrane exporter, YdcZ 31 179 7.6E-25 T 12-10-2018 IPR006750 Putative inner membrane exporter, YdcZ UA74_19200 ca8c174d518ab014a218b28a4e315a4f 231 SMART SM00862 145 217 2.4E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_19200 ca8c174d518ab014a218b28a4e315a4f 231 Gene3D G3DSA:1.10.10.10 121 222 6.7E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19200 ca8c174d518ab014a218b28a4e315a4f 231 SMART SM00448 1 112 4.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_19200 ca8c174d518ab014a218b28a4e315a4f 231 SUPERFAMILY SSF52172 1 170 1.06E-33 T 12-10-2018 IPR011006 CheY-like superfamily UA74_19200 ca8c174d518ab014a218b28a4e315a4f 231 Pfam PF00072 Response regulator receiver domain 3 112 6.3E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_19200 ca8c174d518ab014a218b28a4e315a4f 231 Gene3D G3DSA:3.40.50.2300 1 120 6.3E-30 T 12-10-2018 UA74_19200 ca8c174d518ab014a218b28a4e315a4f 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 217 1.4E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_28260 7ef455571f942989a38218c003c5e503 217 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 6 217 4.2E-75 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_28260 7ef455571f942989a38218c003c5e503 217 SUPERFAMILY SSF50475 16 217 3.1E-63 T 12-10-2018 UA74_28260 7ef455571f942989a38218c003c5e503 217 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 187 200 - T 12-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_28260 7ef455571f942989a38218c003c5e503 217 Gene3D G3DSA:2.30.110.10 14 216 1.4E-75 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_28260 7ef455571f942989a38218c003c5e503 217 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 14 217 36.222 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_28260 7ef455571f942989a38218c003c5e503 217 PIRSF PIRSF000190 2 217 5.8E-77 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_28260 7ef455571f942989a38218c003c5e503 217 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 177 217 3.5E-18 T 12-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_28260 7ef455571f942989a38218c003c5e503 217 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 37 122 1.6E-18 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_05220 629a5f3a4617643fa6765136bea45249 356 SUPERFAMILY SSF51197 49 345 8.24E-53 T 12-10-2018 UA74_05220 629a5f3a4617643fa6765136bea45249 356 Gene3D G3DSA:2.60.120.620 44 356 1.5E-116 T 12-10-2018 UA74_05220 629a5f3a4617643fa6765136bea45249 356 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 59 289 3.7E-36 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase UA74_05220 629a5f3a4617643fa6765136bea45249 356 TIGRFAM TIGR01762 chlorin-enz: chlorinating enzyme 49 343 3.6E-134 T 12-10-2018 IPR010092 Chlorinating enzyme UA74_19095 68baae3850ba5fc0eae1de988adb40ca 762 SUPERFAMILY SSF52540 255 755 1.09E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19095 68baae3850ba5fc0eae1de988adb40ca 762 SUPERFAMILY SSF143011 1 88 1.41E-5 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily UA74_19095 68baae3850ba5fc0eae1de988adb40ca 762 Pfam PF00580 UvrD/REP helicase N-terminal domain 261 538 2.5E-18 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UA74_19095 68baae3850ba5fc0eae1de988adb40ca 762 Gene3D G3DSA:3.30.2310.20 4 94 2.8E-8 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily UA74_19095 68baae3850ba5fc0eae1de988adb40ca 762 Gene3D G3DSA:3.40.50.300 420 544 2.0E-10 T 12-10-2018 UA74_19095 68baae3850ba5fc0eae1de988adb40ca 762 Gene3D G3DSA:3.40.50.300 559 761 4.5E-21 T 12-10-2018 UA74_19095 68baae3850ba5fc0eae1de988adb40ca 762 Gene3D G3DSA:3.40.50.300 255 400 7.4E-18 T 12-10-2018 UA74_19095 68baae3850ba5fc0eae1de988adb40ca 762 Pfam PF13361 UvrD-like helicase C-terminal domain 670 753 1.3E-10 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_11495 d0618ab8b663b608c80e363598d0ffa6 297 Gene3D G3DSA:1.10.10.10 1 93 1.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_11495 d0618ab8b663b608c80e363598d0ffa6 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.4E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_11495 d0618ab8b663b608c80e363598d0ffa6 297 SUPERFAMILY SSF46785 1 112 9.77E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_11495 d0618ab8b663b608c80e363598d0ffa6 297 Gene3D G3DSA:3.40.190.10 167 269 2.4E-44 T 12-10-2018 UA74_11495 d0618ab8b663b608c80e363598d0ffa6 297 Pfam PF03466 LysR substrate binding domain 88 295 1.4E-46 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_11495 d0618ab8b663b608c80e363598d0ffa6 297 SUPERFAMILY SSF53850 90 296 1.28E-42 T 12-10-2018 UA74_11495 d0618ab8b663b608c80e363598d0ffa6 297 Gene3D G3DSA:3.40.190.10 94 283 2.4E-44 T 12-10-2018 UA74_13285 cbee79d24d7f7b10a438fbc88fbaefc5 413 Gene3D G3DSA:1.20.58.1130 191 245 5.0E-15 T 12-10-2018 UA74_13285 cbee79d24d7f7b10a438fbc88fbaefc5 413 Gene3D G3DSA:1.20.1420.30 64 351 5.0E-15 T 12-10-2018 UA74_13285 cbee79d24d7f7b10a438fbc88fbaefc5 413 Pfam PF01699 Sodium/calcium exchanger protein 35 182 1.8E-12 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 UA74_13285 cbee79d24d7f7b10a438fbc88fbaefc5 413 Pfam PF01699 Sodium/calcium exchanger protein 214 357 2.7E-10 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 UA74_07745 0856ccaf6c1dcfa7739defcfe64a1aaf 430 SUPERFAMILY SSF102588 28 222 1.12E-43 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_07745 0856ccaf6c1dcfa7739defcfe64a1aaf 430 SUPERFAMILY SSF53335 246 405 4.96E-20 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_07745 0856ccaf6c1dcfa7739defcfe64a1aaf 430 Gene3D G3DSA:3.40.50.150 266 429 3.1E-33 T 12-10-2018 UA74_07745 0856ccaf6c1dcfa7739defcfe64a1aaf 430 Pfam PF05401 Nodulation protein S (NodS) 258 383 2.4E-14 T 12-10-2018 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 UA74_07745 0856ccaf6c1dcfa7739defcfe64a1aaf 430 Pfam PF02585 GlcNAc-PI de-N-acetylase 31 156 8.7E-26 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_07745 0856ccaf6c1dcfa7739defcfe64a1aaf 430 Gene3D G3DSA:3.40.50.10320 25 233 3.9E-39 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_23480 ab911be2391383dd3b02f3f248cecda0 275 SUPERFAMILY SSF64167 2 242 7.59E-41 T 12-10-2018 UA74_23480 ab911be2391383dd3b02f3f248cecda0 275 Gene3D G3DSA:3.40.1210.10 1 266 4.9E-54 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 UA74_23480 ab911be2391383dd3b02f3f248cecda0 275 Pfam PF01975 Survival protein SurE 3 187 8.2E-41 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 SUPERFAMILY SSF51735 245 407 9.29E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 13 486 1.1E-142 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 SUPERFAMILY SSF52283 12 487 6.23E-109 T 12-10-2018 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 SMART SM00996 13 486 0.0 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 SMART SM00997 245 407 4.2E-105 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 Gene3D G3DSA:3.40.50.1480 16 487 4.3E-235 T 12-10-2018 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 PIRSF PIRSF001109 1 487 1.7E-188 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 267 283 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 14 479 3.6E-189 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 245 407 4.9E-80 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 Gene3D G3DSA:3.40.50.720 248 408 4.3E-235 T 12-10-2018 UA74_26555 889f7d7eab8608df0d4a03df7c4b4c16 487 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 9 479 47.729 T 12-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 UA74_29115 a08d11f11276a9088c5fde18c8b3dc62 335 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 7 335 33.58 T 12-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 UA74_29115 a08d11f11276a9088c5fde18c8b3dc62 335 PIRSF PIRSF021524 3 335 3.4E-105 T 12-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 UA74_29115 a08d11f11276a9088c5fde18c8b3dc62 335 Pfam PF00583 Acetyltransferase (GNAT) family 224 324 1.4E-16 T 12-10-2018 IPR000182 GNAT domain UA74_29115 a08d11f11276a9088c5fde18c8b3dc62 335 Pfam PF00583 Acetyltransferase (GNAT) family 65 121 4.9E-7 T 12-10-2018 IPR000182 GNAT domain UA74_29115 a08d11f11276a9088c5fde18c8b3dc62 335 Gene3D G3DSA:3.40.630.30 2 335 1.5E-86 T 12-10-2018 UA74_29115 a08d11f11276a9088c5fde18c8b3dc62 335 SUPERFAMILY SSF55729 139 327 1.65E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_29115 a08d11f11276a9088c5fde18c8b3dc62 335 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 9 332 5.5E-86 T 12-10-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 UA74_29115 a08d11f11276a9088c5fde18c8b3dc62 335 SUPERFAMILY SSF55729 54 172 1.77E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_14645 d8881d4830a26b93590a015fa4316016 545 SUPERFAMILY SSF52540 335 537 1.09E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14645 d8881d4830a26b93590a015fa4316016 545 Gene3D G3DSA:3.40.50.300 308 542 3.7E-39 T 12-10-2018 UA74_14645 d8881d4830a26b93590a015fa4316016 545 SUPERFAMILY SSF52540 6 221 3.55E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14645 d8881d4830a26b93590a015fa4316016 545 SMART SM00382 367 533 1.1E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_14645 d8881d4830a26b93590a015fa4316016 545 SMART SM00382 30 215 8.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_14645 d8881d4830a26b93590a015fa4316016 545 Gene3D G3DSA:3.40.50.300 3 266 3.7E-56 T 12-10-2018 UA74_14645 d8881d4830a26b93590a015fa4316016 545 Pfam PF00005 ABC transporter 360 489 1.3E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_14645 d8881d4830a26b93590a015fa4316016 545 Pfam PF00005 ABC transporter 23 171 1.1E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_16325 67c4212418be822ab44947d52838a214 1628 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1471 1567 2.3E-17 T 12-10-2018 UA74_16325 67c4212418be822ab44947d52838a214 1628 SUPERFAMILY SSF52540 34 1590 5.84E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07380 7a24e598d40a22a7293f3b1ac3386b84 310 Gene3D G3DSA:3.40.50.720 1 178 7.7E-36 T 12-10-2018 UA74_07380 7a24e598d40a22a7293f3b1ac3386b84 310 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 179 298 1.1E-24 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain UA74_07380 7a24e598d40a22a7293f3b1ac3386b84 310 Gene3D G3DSA:1.10.1040.10 179 303 3.4E-26 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_07380 7a24e598d40a22a7293f3b1ac3386b84 310 SUPERFAMILY SSF51735 2 132 4.73E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_07380 7a24e598d40a22a7293f3b1ac3386b84 310 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 151 7.9E-27 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain UA74_07380 7a24e598d40a22a7293f3b1ac3386b84 310 SUPERFAMILY SSF48179 179 298 3.74E-23 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_07380 7a24e598d40a22a7293f3b1ac3386b84 310 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 301 3.1E-59 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 UA74_07105 e7e9bd96bd3ab96148bda5ce7677de6b 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 208 8.5E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_07105 e7e9bd96bd3ab96148bda5ce7677de6b 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 7 103 3.7E-23 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UA74_07105 e7e9bd96bd3ab96148bda5ce7677de6b 232 Gene3D G3DSA:1.10.3720.10 3 211 2.6E-47 T 12-10-2018 IPR035906 MetI-like superfamily UA74_07105 e7e9bd96bd3ab96148bda5ce7677de6b 232 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 8 209 1.8E-71 T 12-10-2018 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC UA74_07105 e7e9bd96bd3ab96148bda5ce7677de6b 232 SUPERFAMILY SSF161098 6 194 1.01E-39 T 12-10-2018 IPR035906 MetI-like superfamily UA74_13585 7a604cd60892bb71e71099e210b2d253 225 SMART SM01007 20 209 1.8E-37 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal UA74_13585 7a604cd60892bb71e71099e210b2d253 225 SUPERFAMILY SSF53639 20 213 6.47E-37 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UA74_13585 7a604cd60892bb71e71099e210b2d253 225 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 25 212 3.9E-49 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 UA74_13585 7a604cd60892bb71e71099e210b2d253 225 Gene3D G3DSA:3.40.225.10 16 220 1.7E-44 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UA74_13585 7a604cd60892bb71e71099e210b2d253 225 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 217 70.359 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 UA74_13585 7a604cd60892bb71e71099e210b2d253 225 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 22 206 7.8E-33 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal UA74_11045 6b19db4adc5d29e0ae5edd6950cfbfb0 181 Pfam PF00364 Biotin-requiring enzyme 103 174 3.9E-15 T 12-10-2018 IPR000089 Biotin/lipoyl attachment UA74_11045 6b19db4adc5d29e0ae5edd6950cfbfb0 181 SUPERFAMILY SSF51230 101 176 2.75E-20 T 12-10-2018 IPR011053 Single hybrid motif UA74_11045 6b19db4adc5d29e0ae5edd6950cfbfb0 181 Gene3D G3DSA:2.40.50.100 97 176 6.8E-25 T 12-10-2018 UA74_11045 6b19db4adc5d29e0ae5edd6950cfbfb0 181 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 122 136 8.1E-13 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UA74_11045 6b19db4adc5d29e0ae5edd6950cfbfb0 181 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 105 118 8.1E-13 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UA74_11045 6b19db4adc5d29e0ae5edd6950cfbfb0 181 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 137 150 8.1E-13 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UA74_14295 5cb9c3179a5c32c4251b492983609dd9 121 Gene3D G3DSA:1.10.490.10 2 121 3.9E-41 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UA74_14295 5cb9c3179a5c32c4251b492983609dd9 121 Pfam PF01152 Bacterial-like globin 4 116 1.4E-26 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 UA74_14295 5cb9c3179a5c32c4251b492983609dd9 121 PIRSF PIRSF002030 1 119 8.7E-40 T 12-10-2018 IPR016339 Truncated hemoglobin, group 1 UA74_14295 5cb9c3179a5c32c4251b492983609dd9 121 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 51 71 - T 12-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 UA74_14295 5cb9c3179a5c32c4251b492983609dd9 121 SUPERFAMILY SSF46458 3 117 2.18E-35 T 12-10-2018 IPR009050 Globin-like superfamily UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 Pfam PF00082 Subtilase family 173 443 2.2E-37 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 Pfam PF13620 Carboxypeptidase regulatory-like domain 564 639 4.9E-9 T 12-10-2018 UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 Pfam PF13620 Carboxypeptidase regulatory-like domain 481 557 1.2E-10 T 12-10-2018 UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 231 241 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 SUPERFAMILY SSF49452 558 639 3.14E-9 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 PRINTS PR00723 Subtilisin serine protease family (S8) signature 173 192 2.2E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 PRINTS PR00723 Subtilisin serine protease family (S8) signature 403 419 2.2E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 PRINTS PR00723 Subtilisin serine protease family (S8) signature 227 240 2.2E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 Gene3D G3DSA:2.60.40.1120 481 557 2.1E-14 T 12-10-2018 UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 SUPERFAMILY SSF52743 150 473 3.27E-59 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 Gene3D G3DSA:2.60.40.1120 563 641 3.7E-7 T 12-10-2018 UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 SUPERFAMILY SSF49452 475 556 3.33E-11 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 Gene3D G3DSA:3.40.50.200 145 473 1.4E-63 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_11230 d5555bc68919dc9d8eb446432aeb1d83 837 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 404 414 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_10505 3a978f8201a9d4f1827458b545b5c85e 222 Pfam PF00072 Response regulator receiver domain 5 117 4.8E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_10505 3a978f8201a9d4f1827458b545b5c85e 222 Gene3D G3DSA:3.40.50.12740 4 209 2.9E-62 T 12-10-2018 UA74_10505 3a978f8201a9d4f1827458b545b5c85e 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 5.4E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_10505 3a978f8201a9d4f1827458b545b5c85e 222 SMART SM00421 148 205 5.6E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_10505 3a978f8201a9d4f1827458b545b5c85e 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 4.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_10505 3a978f8201a9d4f1827458b545b5c85e 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 4.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_10505 3a978f8201a9d4f1827458b545b5c85e 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 4.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_10505 3a978f8201a9d4f1827458b545b5c85e 222 SMART SM00448 3 116 3.1E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_10505 3a978f8201a9d4f1827458b545b5c85e 222 SUPERFAMILY SSF52172 4 181 9.81E-30 T 12-10-2018 IPR011006 CheY-like superfamily UA74_20260 ab4373f8025f72bd9d9aa1b81cd7f218 266 SUPERFAMILY SSF53474 1 249 1.53E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_10290 999f19d6fa575e2d69149606745d7663 484 Pfam PF01569 PAP2 superfamily 95 202 3.1E-23 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_10290 999f19d6fa575e2d69149606745d7663 484 SMART SM00014 93 202 2.9E-13 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_10290 999f19d6fa575e2d69149606745d7663 484 Gene3D G3DSA:1.20.144.10 129 219 1.7E-18 T 12-10-2018 UA74_10290 999f19d6fa575e2d69149606745d7663 484 SUPERFAMILY SSF48317 54 203 3.01E-30 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily UA74_24140 d6710112f04bec2151474a2df72fd69f 164 Gene3D G3DSA:3.10.180.10 28 164 1.6E-55 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_24140 d6710112f04bec2151474a2df72fd69f 164 SUPERFAMILY SSF54593 32 159 2.95E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_24465 ce2e0704d15e470a0932ee083ebdac59 302 Hamap MF_00367 GTPase Era [era]. 8 302 34.246 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_24465 ce2e0704d15e470a0932ee083ebdac59 302 SUPERFAMILY SSF54814 187 302 1.09E-34 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UA74_24465 ce2e0704d15e470a0932ee083ebdac59 302 TIGRFAM TIGR00436 era: GTP-binding protein Era 11 285 2.8E-67 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_24465 ce2e0704d15e470a0932ee083ebdac59 302 Pfam PF01926 50S ribosome-binding GTPase 13 129 2.6E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_24465 ce2e0704d15e470a0932ee083ebdac59 302 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 171 3.5E-17 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_24465 ce2e0704d15e470a0932ee083ebdac59 302 SUPERFAMILY SSF52540 14 218 5.08E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24465 ce2e0704d15e470a0932ee083ebdac59 302 Pfam PF07650 KH domain 212 291 1.8E-17 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_24465 ce2e0704d15e470a0932ee083ebdac59 302 Gene3D G3DSA:3.40.50.300 6 187 3.5E-41 T 12-10-2018 UA74_24465 ce2e0704d15e470a0932ee083ebdac59 302 Gene3D G3DSA:3.30.300.20 189 302 1.4E-40 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_05400 0380d3e5fb3e29b3691f85fc2ba05bc1 365 Pfam PF03088 Strictosidine synthase 156 248 7.1E-20 T 12-10-2018 IPR018119 Strictosidine synthase, conserved region GO:0009058|GO:0016844 UA74_05400 0380d3e5fb3e29b3691f85fc2ba05bc1 365 Gene3D G3DSA:2.120.10.30 56 308 2.4E-59 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_05400 0380d3e5fb3e29b3691f85fc2ba05bc1 365 SUPERFAMILY SSF63829 34 343 2.62E-47 T 12-10-2018 UA74_29365 1aa4531262724f37105e030f9392fb03 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_29365 1aa4531262724f37105e030f9392fb03 430 Gene3D G3DSA:3.90.170.10 266 428 4.3E-68 T 12-10-2018 UA74_29365 1aa4531262724f37105e030f9392fb03 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 424 7.4E-163 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_29365 1aa4531262724f37105e030f9392fb03 430 Gene3D G3DSA:3.40.440.10 7 256 3.4E-97 T 12-10-2018 UA74_29365 1aa4531262724f37105e030f9392fb03 430 Gene3D G3DSA:1.10.300.10 101 200 3.4E-97 T 12-10-2018 UA74_29365 1aa4531262724f37105e030f9392fb03 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 200.595 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_29365 1aa4531262724f37105e030f9392fb03 430 SUPERFAMILY SSF52540 1 423 5.52E-168 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29365 1aa4531262724f37105e030f9392fb03 430 SMART SM00788 3 423 1.8E-275 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_29365 1aa4531262724f37105e030f9392fb03 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_29365 1aa4531262724f37105e030f9392fb03 430 Pfam PF00709 Adenylosuccinate synthetase 4 422 1.4E-176 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UA74_23340 48b90b524cf5796a1947cd01831070c6 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 6.3E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_23340 48b90b524cf5796a1947cd01831070c6 189 Pfam PF13305 WHG domain 84 160 1.0E-8 T 12-10-2018 IPR025996 WHG domain UA74_23340 48b90b524cf5796a1947cd01831070c6 189 Gene3D G3DSA:1.10.10.60 1 49 1.5E-17 T 12-10-2018 UA74_23340 48b90b524cf5796a1947cd01831070c6 189 Gene3D G3DSA:1.10.357.10 51 184 2.7E-28 T 12-10-2018 UA74_23340 48b90b524cf5796a1947cd01831070c6 189 SUPERFAMILY SSF48498 77 183 1.78E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_23340 48b90b524cf5796a1947cd01831070c6 189 SUPERFAMILY SSF46689 8 69 1.18E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_00885 84038e5cc5015c3768222705f0bacf71 219 SUPERFAMILY SSF52218 2 213 2.62E-27 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_00885 84038e5cc5015c3768222705f0bacf71 219 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 206 19.159 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 UA74_00885 84038e5cc5015c3768222705f0bacf71 219 Gene3D G3DSA:3.40.50.360 1 208 3.8E-31 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_00885 84038e5cc5015c3768222705f0bacf71 219 Pfam PF02525 Flavodoxin-like fold 1 167 4.8E-21 T 12-10-2018 IPR003680 Flavodoxin-like fold UA74_19185 d3a09fd77080ae177c87c192a3e7e361 222 Pfam PF02080 TrkA-C domain 155 221 6.6E-12 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_19185 d3a09fd77080ae177c87c192a3e7e361 222 SUPERFAMILY SSF51735 9 139 2.03E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_19185 d3a09fd77080ae177c87c192a3e7e361 222 Pfam PF02254 TrkA-N domain 12 126 1.3E-23 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UA74_19185 d3a09fd77080ae177c87c192a3e7e361 222 Gene3D G3DSA:3.30.70.1450 143 220 2.8E-20 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UA74_19185 d3a09fd77080ae177c87c192a3e7e361 222 SUPERFAMILY SSF116726 136 221 2.09E-17 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UA74_19185 d3a09fd77080ae177c87c192a3e7e361 222 Gene3D G3DSA:3.40.50.720 5 142 1.4E-29 T 12-10-2018 UA74_08930 fea5a8085b8a42947f682ec38115b99a 173 Pfam PF01551 Peptidase family M23 65 159 6.0E-17 T 12-10-2018 IPR016047 Peptidase M23 UA74_08930 fea5a8085b8a42947f682ec38115b99a 173 SUPERFAMILY SSF51261 39 163 1.78E-19 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_08930 fea5a8085b8a42947f682ec38115b99a 173 Gene3D G3DSA:2.70.70.10 25 165 2.2E-22 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_05245 fcbecc5e88c1d8d2c04180215e920fa2 448 SMART SM00387 345 436 2.5E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_05245 fcbecc5e88c1d8d2c04180215e920fa2 448 SUPERFAMILY SSF55874 312 433 1.83E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_05245 fcbecc5e88c1d8d2c04180215e920fa2 448 PIRSF PIRSF037434 18 439 1.3E-68 T 12-10-2018 IPR017205 Signal transduction histidine kinase, ChrS UA74_05245 fcbecc5e88c1d8d2c04180215e920fa2 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 433 9.4E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_05245 fcbecc5e88c1d8d2c04180215e920fa2 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 433 1.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_05245 fcbecc5e88c1d8d2c04180215e920fa2 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 1.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_05245 fcbecc5e88c1d8d2c04180215e920fa2 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 1.9E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_05245 fcbecc5e88c1d8d2c04180215e920fa2 448 Gene3D G3DSA:3.30.565.10 308 434 2.5E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_05245 fcbecc5e88c1d8d2c04180215e920fa2 448 Pfam PF07730 Histidine kinase 241 307 4.7E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_02970 9a6e5efeabb898f6a41369ee7466af95 143 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 21 123 1.5E-46 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02970 9a6e5efeabb898f6a41369ee7466af95 143 Pfam PF00237 Ribosomal protein L22p/L17e 21 123 1.8E-35 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 UA74_02970 9a6e5efeabb898f6a41369ee7466af95 143 SUPERFAMILY SSF54843 10 127 9.03E-43 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 UA74_02970 9a6e5efeabb898f6a41369ee7466af95 143 Gene3D G3DSA:3.90.470.10 16 141 4.2E-48 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 UA74_02970 9a6e5efeabb898f6a41369ee7466af95 143 ProSitePatterns PS00464 Ribosomal protein L22 signature. 99 123 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02970 9a6e5efeabb898f6a41369ee7466af95 143 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 17 126 29.467 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_17590 0407bff87aa4bbceceb68d1ba2b33066 649 Pfam PF00501 AMP-binding enzyme 38 440 3.0E-71 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_17590 0407bff87aa4bbceceb68d1ba2b33066 649 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 530 2.0E-7 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_17590 0407bff87aa4bbceceb68d1ba2b33066 649 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_17590 0407bff87aa4bbceceb68d1ba2b33066 649 Gene3D G3DSA:3.30.300.30 434 545 2.7E-16 T 12-10-2018 UA74_17590 0407bff87aa4bbceceb68d1ba2b33066 649 Gene3D G3DSA:3.40.50.12780 25 433 1.1E-94 T 12-10-2018 UA74_17590 0407bff87aa4bbceceb68d1ba2b33066 649 SUPERFAMILY SSF56801 29 538 1.83E-108 T 12-10-2018 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 Gene3D G3DSA:3.40.50.12740 5 218 7.2E-66 T 12-10-2018 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 SUPERFAMILY SSF46894 151 218 1.36E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 SUPERFAMILY SSF52172 4 139 2.28E-30 T 12-10-2018 IPR011006 CheY-like superfamily UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 3.6E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 3.6E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 3.6E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 Pfam PF00072 Response regulator receiver domain 7 119 6.1E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 SMART SM00421 155 212 4.6E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 2.3E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_07460 66c5c757a7d44a925ff8cfd9fffb2c56 219 SMART SM00448 5 120 2.6E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 Gene3D G3DSA:3.40.50.1240 156 311 2.0E-36 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 Pfam PF00293 NUDIX domain 14 148 1.9E-22 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 SUPERFAMILY SSF53254 156 308 2.57E-20 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 SUPERFAMILY SSF55811 12 150 1.62E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 158 254 3.4E-12 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 SMART SM00855 157 271 6.9E-10 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 Gene3D G3DSA:3.90.79.10 13 153 1.1E-38 T 12-10-2018 UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 PRINTS PR00502 NUDIX hydrolase family signature 46 60 8.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_25830 da2ed8cc71c3e06ec2c1cbfd5cc66d8a 319 PRINTS PR00502 NUDIX hydrolase family signature 60 75 8.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_08615 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 282 28.998 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UA74_08615 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Gene3D G3DSA:3.10.310.10 142 278 1.1E-83 T 12-10-2018 UA74_08615 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Pfam PF01678 Diaminopimelate epimerase 151 274 5.0E-21 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UA74_08615 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Pfam PF01678 Diaminopimelate epimerase 6 133 5.3E-33 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UA74_08615 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 SUPERFAMILY SSF54506 4 135 2.69E-34 T 12-10-2018 UA74_08615 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 Gene3D G3DSA:3.10.310.10 6 141 1.1E-83 T 12-10-2018 UA74_08615 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 SUPERFAMILY SSF54506 141 280 3.14E-28 T 12-10-2018 UA74_08615 c8bc4196b9ebd0e1eed8429ab1bea6c5 291 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 280 9.1E-63 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UA74_03910 c09af71db68821d831ba933803027038 384 SMART SM00922 132 237 2.1E-21 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_03910 c09af71db68821d831ba933803027038 384 Pfam PF13378 Enolase C-terminal domain-like 137 358 1.5E-65 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_03910 c09af71db68821d831ba933803027038 384 SUPERFAMILY SSF54826 3 116 1.85E-26 T 12-10-2018 UA74_03910 c09af71db68821d831ba933803027038 384 SUPERFAMILY SSF51604 99 365 9.04E-81 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_03910 c09af71db68821d831ba933803027038 384 Gene3D G3DSA:3.30.390.10 6 360 3.7E-123 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_03910 c09af71db68821d831ba933803027038 384 Gene3D G3DSA:3.20.20.120 105 350 3.7E-123 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_03910 c09af71db68821d831ba933803027038 384 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 111 9.2E-14 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_28455 6fbd608306b8d5268f41bd5937320ff4 203 SUPERFAMILY SSF52540 21 194 2.85E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28455 6fbd608306b8d5268f41bd5937320ff4 203 Gene3D G3DSA:3.40.50.300 14 198 6.2E-18 T 12-10-2018 UA74_28455 6fbd608306b8d5268f41bd5937320ff4 203 Pfam PF03029 Conserved hypothetical ATP binding protein 26 194 1.1E-27 T 12-10-2018 IPR004130 GPN-loop GTPase UA74_16040 510699e1e01f7962835ac8ed7afe6300 315 Gene3D G3DSA:3.20.20.70 11 288 2.3E-43 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_16040 510699e1e01f7962835ac8ed7afe6300 315 SUPERFAMILY SSF102114 14 287 2.62E-50 T 12-10-2018 UA74_16040 510699e1e01f7962835ac8ed7afe6300 315 Pfam PF13353 4Fe-4S single cluster domain 16 124 4.0E-7 T 12-10-2018 UA74_16040 510699e1e01f7962835ac8ed7afe6300 315 Pfam PF04055 Radical SAM superfamily 21 162 2.5E-20 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_16040 510699e1e01f7962835ac8ed7afe6300 315 SMART SM00729 15 216 3.9E-10 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_28470 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 SMART SM00387 567 678 1.1E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_28470 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 SUPERFAMILY SSF55874 554 676 2.36E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_28470 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 571 671 8.1E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_28470 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 Gene3D G3DSA:3.30.565.10 504 670 3.0E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_28470 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 Pfam PF00672 HAMP domain 385 452 1.9E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_28470 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 Pfam PF08376 Nitrate and nitrite sensing 109 347 6.5E-37 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein UA74_28470 2e6c8ff012dadbf81d1dcaba1b8bdeda 1122 SMART SM00304 385 455 0.0026 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 Pfam PF00571 CBS domain 192 246 4.0E-6 T 12-10-2018 IPR000644 CBS domain UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 Pfam PF00571 CBS domain 127 183 1.4E-6 T 12-10-2018 IPR000644 CBS domain UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 SMART SM00924 24 127 1.0E-24 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 Gene3D G3DSA:1.25.60.10 1 122 1.3E-19 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 Gene3D G3DSA:3.10.580.10 124 250 1.1E-36 T 12-10-2018 UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 SUPERFAMILY SSF54631 126 264 1.89E-30 T 12-10-2018 UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 SUPERFAMILY SSF161093 270 440 3.27E-48 T 12-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 TIGRFAM TIGR00400 mgtE: magnesium transporter 5 441 6.9E-119 T 12-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 Pfam PF01769 Divalent cation transporter 313 434 1.1E-29 T 12-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 Pfam PF03448 MgtE intracellular N domain 26 124 2.3E-20 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 SMART SM00116 134 187 3.0 T 12-10-2018 IPR000644 CBS domain UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 SMART SM00116 198 246 8.5E-6 T 12-10-2018 IPR000644 CBS domain UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 SUPERFAMILY SSF158791 3 124 5.1E-24 T 12-10-2018 UA74_25360 64ddb6f60b4198d56234a9416e24ae82 442 Gene3D G3DSA:1.10.357.20 265 440 2.1E-54 T 12-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain UA74_10565 228612cf6e8f64e3355e2a73730408d4 297 Gene3D G3DSA:3.40.50.300 3 297 1.2E-64 T 12-10-2018 UA74_10565 228612cf6e8f64e3355e2a73730408d4 297 SUPERFAMILY SSF52540 7 256 2.43E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10565 228612cf6e8f64e3355e2a73730408d4 297 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 9 253 2.3E-53 T 12-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 UA74_10565 228612cf6e8f64e3355e2a73730408d4 297 Pfam PF02374 Anion-transporting ATPase 7 254 1.3E-50 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 UA74_23395 5c376166dd49b714110a67ac2ee9529b 655 Gene3D G3DSA:1.10.510.10 104 278 4.2E-9 T 12-10-2018 UA74_23395 5c376166dd49b714110a67ac2ee9529b 655 SUPERFAMILY SSF56112 41 201 1.25E-12 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_28560 00b3ac6664ab225305efb3bcb6b0421e 212 Gene3D G3DSA:3.60.160.10 1 212 9.9E-33 T 12-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily UA74_28560 00b3ac6664ab225305efb3bcb6b0421e 212 Pfam PF01987 Mitochondrial biogenesis AIM24 10 205 1.8E-28 T 12-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 UA74_28560 00b3ac6664ab225305efb3bcb6b0421e 212 SUPERFAMILY SSF51219 4 209 9.16E-30 T 12-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily UA74_05495 6a6085207fa3351aef54a5a744b13f46 586 Gene3D G3DSA:1.10.287.1060 78 170 6.7E-5 T 12-10-2018 UA74_05495 6a6085207fa3351aef54a5a744b13f46 586 SUPERFAMILY SSF140453 83 170 8.37E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_03125 085f8e577998de0f29c93cc32db62de9 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 2.5E-51 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_03125 085f8e577998de0f29c93cc32db62de9 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 2.9E-32 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03125 085f8e577998de0f29c93cc32db62de9 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 26.499 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03125 085f8e577998de0f29c93cc32db62de9 126 Gene3D G3DSA:4.10.910.10 73 126 2.1E-24 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03125 085f8e577998de0f29c93cc32db62de9 126 Gene3D G3DSA:1.10.8.50 1 72 1.1E-30 T 12-10-2018 UA74_03125 085f8e577998de0f29c93cc32db62de9 126 PIRSF PIRSF002134 1 125 9.4E-44 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03125 085f8e577998de0f29c93cc32db62de9 126 SUPERFAMILY SSF46946 2 124 6.93E-46 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 Gene3D G3DSA:3.40.50.800 367 461 5.6E-27 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 SUPERFAMILY SSF52954 356 461 7.55E-30 T 12-10-2018 UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 Pfam PF03129 Anticodon binding domain 369 456 2.6E-18 T 12-10-2018 IPR004154 Anticodon-binding UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 2.6E-43 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 2.6E-43 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 406 425 2.6E-43 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 2.6E-43 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 2.6E-43 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 320 332 2.6E-43 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UA74_24380 185b5b125e5cff8ed5c0d0d7a5a19424 463 SUPERFAMILY SSF55681 7 372 3.55E-98 T 12-10-2018 UA74_25790 e9e5e27ae567b7c5097f9843513fb336 484 Gene3D G3DSA:3.40.640.10 106 465 1.5E-75 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_25790 e9e5e27ae567b7c5097f9843513fb336 484 SUPERFAMILY SSF53383 84 471 3.35E-63 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_25790 e9e5e27ae567b7c5097f9843513fb336 484 Pfam PF00155 Aminotransferase class I and II 182 417 2.0E-10 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_25790 e9e5e27ae567b7c5097f9843513fb336 484 SUPERFAMILY SSF46785 19 93 1.48E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_25790 e9e5e27ae567b7c5097f9843513fb336 484 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 89 1.7E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_25790 e9e5e27ae567b7c5097f9843513fb336 484 SMART SM00345 30 89 2.2E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_25790 e9e5e27ae567b7c5097f9843513fb336 484 Gene3D G3DSA:1.10.10.10 12 90 6.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 Gene3D G3DSA:3.40.30.10 1 169 4.3E-67 T 12-10-2018 UA74_04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 468 522 0.052 T 12-10-2018 UA74_04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 Pfam PF03190 Protein of unknown function, DUF255 3 163 1.3E-73 T 12-10-2018 IPR004879 Domain of unknown function DUF255 UA74_04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 SUPERFAMILY SSF52833 2 126 1.85E-29 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 SUPERFAMILY SSF48208 187 549 2.04E-70 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_04070 f739f6bd19a370f4b8a7dabb1f0622f2 692 PIRSF PIRSF006402 1 692 1.5E-201 T 12-10-2018 IPR024705 Spermatogenesis-associated protein 20 UA74_01455 4be6d8886431616a0c44bec6bc99586e 744 Gene3D G3DSA:3.40.50.300 519 716 2.1E-30 T 12-10-2018 UA74_01455 4be6d8886431616a0c44bec6bc99586e 744 Pfam PF05977 Transmembrane secretion effector 292 458 2.7E-6 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_01455 4be6d8886431616a0c44bec6bc99586e 744 Pfam PF05977 Transmembrane secretion effector 43 217 2.5E-11 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_01455 4be6d8886431616a0c44bec6bc99586e 744 Hamap MF_00165 Thymidylate kinase [tmk]. 522 713 15.546 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_01455 4be6d8886431616a0c44bec6bc99586e 744 Pfam PF02223 Thymidylate kinase 536 700 1.4E-10 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 UA74_01455 4be6d8886431616a0c44bec6bc99586e 744 SUPERFAMILY SSF52540 521 708 1.26E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01455 4be6d8886431616a0c44bec6bc99586e 744 SUPERFAMILY SSF103473 48 493 6.93E-31 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 Pfam PF04898 Glutamate synthase central domain 494 780 3.4E-108 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 SUPERFAMILY SSF69336 1265 1526 4.19E-88 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 Gene3D G3DSA:3.20.20.70 831 1252 1.3E-183 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 Gene3D G3DSA:3.20.20.70 475 830 6.0E-130 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 SUPERFAMILY SSF56235 22 469 5.52E-136 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 Gene3D G3DSA:2.160.20.60 1268 1535 3.4E-100 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 Pfam PF01493 GXGXG motif 1296 1473 1.3E-74 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 SUPERFAMILY SSF51395 482 1243 1.06E-253 T 12-10-2018 UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 Gene3D G3DSA:3.60.20.10 22 474 1.7E-166 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 Pfam PF00310 Glutamine amidotransferases class-II 22 467 8.1E-161 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain UA74_21340 ecb05f4944b60f4f661d0bca6053cb8f 1547 Pfam PF01645 Conserved region in glutamate synthase 846 1210 5.3E-150 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 UA74_05570 d528270ea555eece0dbef747507bc8cf 267 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 95 100 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 UA74_05570 d528270ea555eece0dbef747507bc8cf 267 SUPERFAMILY SSF50494 55 265 1.41E-35 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_05570 d528270ea555eece0dbef747507bc8cf 267 Pfam PF00089 Trypsin 68 261 1.8E-21 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_05570 d528270ea555eece0dbef747507bc8cf 267 Gene3D G3DSA:2.40.10.10 170 266 1.7E-10 T 12-10-2018 UA74_05570 d528270ea555eece0dbef747507bc8cf 267 Gene3D G3DSA:2.40.10.10 71 155 3.2E-13 T 12-10-2018 UA74_05570 d528270ea555eece0dbef747507bc8cf 267 SMART SM00020 60 261 7.0E-13 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_05570 d528270ea555eece0dbef747507bc8cf 267 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 131 145 1.1E-6 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_05570 d528270ea555eece0dbef747507bc8cf 267 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 213 225 1.1E-6 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_05570 d528270ea555eece0dbef747507bc8cf 267 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 85 100 1.1E-6 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 Pfam PF01556 DnaJ C terminal domain 146 358 2.8E-35 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 PRINTS PR00625 DnaJ domain signature 47 67 2.5E-21 T 12-10-2018 IPR001623 DnaJ domain UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 PRINTS PR00625 DnaJ domain signature 12 30 2.5E-21 T 12-10-2018 IPR001623 DnaJ domain UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 PRINTS PR00625 DnaJ domain signature 67 86 2.5E-21 T 12-10-2018 IPR001623 DnaJ domain UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 PRINTS PR00625 DnaJ domain signature 30 45 2.5E-21 T 12-10-2018 IPR001623 DnaJ domain UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 Gene3D G3DSA:2.10.230.10 170 232 1.1E-19 T 12-10-2018 UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 SUPERFAMILY SSF46565 9 109 4.58E-28 T 12-10-2018 IPR036869 Chaperone J-domain superfamily UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 Gene3D G3DSA:2.60.260.20 233 278 4.9E-13 T 12-10-2018 UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 Gene3D G3DSA:1.10.287.110 7 120 1.8E-28 T 12-10-2018 IPR036869 Chaperone J-domain superfamily UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 SUPERFAMILY SSF49493 285 368 1.83E-18 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 SMART SM00271 9 67 9.9E-26 T 12-10-2018 IPR001623 DnaJ domain UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 Pfam PF00684 DnaJ central domain 173 233 2.3E-13 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 Gene3D G3DSA:2.60.260.20 280 386 5.6E-26 T 12-10-2018 UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 SUPERFAMILY SSF49493 139 292 2.09E-21 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 SUPERFAMILY SSF57938 160 235 6.15E-20 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 Pfam PF00226 DnaJ domain 10 72 9.5E-25 T 12-10-2018 IPR001623 DnaJ domain UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 391 36.46 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 UA74_29700 fd7d7d73d96ac30f4861b33a0cf478f0 395 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 375 1.3E-115 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 28 71 9.3E-7 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 SMART SM00926 26 76 3.5E-8 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 Pfam PF01568 Molydopterin dinucleotide binding domain 598 705 1.5E-26 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 Gene3D G3DSA:3.40.228.10 159 358 1.1E-151 T 12-10-2018 UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 Gene3D G3DSA:2.20.25.90 27 76 9.1E-9 T 12-10-2018 UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 SUPERFAMILY SSF50692 560 708 2.49E-42 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 Pfam PF00384 Molybdopterin oxidoreductase 79 505 1.4E-66 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 Gene3D G3DSA:3.40.50.740 88 555 1.1E-151 T 12-10-2018 UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 SUPERFAMILY SSF53706 29 600 1.96E-159 T 12-10-2018 UA74_09385 cb4e0b54a8f0dbdd10962d5c6b778384 723 Gene3D G3DSA:2.40.40.20 588 710 4.1E-37 T 12-10-2018 UA74_16875 d3908a2fc779e3476995b281573d8dbd 487 Pfam PF01425 Amidase 31 459 3.3E-84 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_16875 d3908a2fc779e3476995b281573d8dbd 487 SUPERFAMILY SSF75304 5 480 7.19E-112 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_16875 d3908a2fc779e3476995b281573d8dbd 487 Gene3D G3DSA:3.90.1300.10 4 485 1.6E-133 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_16875 d3908a2fc779e3476995b281573d8dbd 487 ProSitePatterns PS00571 Amidases signature. 149 180 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 Pfam PF02357 Transcription termination factor nusG 82 184 8.4E-25 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 PRINTS PR00338 Transcription termination factor NUSG signature 241 257 4.9E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 PRINTS PR00338 Transcription termination factor NUSG signature 135 147 4.9E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 PRINTS PR00338 Transcription termination factor NUSG signature 223 238 4.9E-20 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 83 265 1.9E-65 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 Gene3D G3DSA:2.30.30.30 204 265 3.7E-25 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 80 265 24.317 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 SUPERFAMILY SSF50104 209 265 4.21E-17 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 Gene3D G3DSA:3.30.70.940 77 195 9.1E-41 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 SUPERFAMILY SSF82679 82 185 1.02E-35 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 ProSitePatterns PS01014 Transcription termination factor nusG signature. 248 257 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site UA74_02835 1d55f00626da40bcd77a21ec408643a7 265 SMART SM00738 80 188 1.5E-50 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UA74_12335 5df7599b6b5bd775767fac46ecc56a2a 300 SUPERFAMILY SSF52540 20 169 2.42E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12335 5df7599b6b5bd775767fac46ecc56a2a 300 Pfam PF03668 P-loop ATPase protein family 16 300 4.6E-109 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 UA74_12335 5df7599b6b5bd775767fac46ecc56a2a 300 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 16 299 40.889 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 UA74_12335 5df7599b6b5bd775767fac46ecc56a2a 300 Gene3D G3DSA:3.40.50.300 17 180 5.9E-5 T 12-10-2018 UA74_12335 5df7599b6b5bd775767fac46ecc56a2a 300 PIRSF PIRSF005052 16 300 8.6E-111 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 UA74_26890 e9b4481b8f74d5ca5926426bf4df558a 160 Pfam PF12728 Helix-turn-helix domain 80 127 1.8E-12 T 12-10-2018 UA74_26890 e9b4481b8f74d5ca5926426bf4df558a 160 SUPERFAMILY SSF46955 80 126 1.45E-5 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_26890 e9b4481b8f74d5ca5926426bf4df558a 160 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 81 125 3.1E-15 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_13835 75e41bdd0efa74a727b60fa13547a6e3 448 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 155 9.2E-22 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UA74_13835 75e41bdd0efa74a727b60fa13547a6e3 448 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 315 444 1.3E-41 T 12-10-2018 IPR019920 F420-binding domain, putative UA74_13835 75e41bdd0efa74a727b60fa13547a6e3 448 Gene3D G3DSA:3.40.50.720 1 155 1.0E-38 T 12-10-2018 UA74_13835 75e41bdd0efa74a727b60fa13547a6e3 448 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 315 394 2.4E-12 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_13835 75e41bdd0efa74a727b60fa13547a6e3 448 SUPERFAMILY SSF50475 315 446 8.93E-34 T 12-10-2018 UA74_13835 75e41bdd0efa74a727b60fa13547a6e3 448 Gene3D G3DSA:1.10.1040.10 156 284 1.1E-40 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_13835 75e41bdd0efa74a727b60fa13547a6e3 448 Gene3D G3DSA:2.30.110.10 314 446 4.1E-42 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_13835 75e41bdd0efa74a727b60fa13547a6e3 448 SUPERFAMILY SSF51735 1 155 9.8E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_04405 70d3d6a38c16dc1bb006acb5f379adb2 106 Gene3D G3DSA:3.30.70.20 2 106 1.4E-45 T 12-10-2018 UA74_04405 70d3d6a38c16dc1bb006acb5f379adb2 106 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_04405 70d3d6a38c16dc1bb006acb5f379adb2 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_04405 70d3d6a38c16dc1bb006acb5f379adb2 106 SUPERFAMILY SSF54862 3 85 1.08E-20 T 12-10-2018 UA74_04405 70d3d6a38c16dc1bb006acb5f379adb2 106 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.7E-17 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 UA74_04405 70d3d6a38c16dc1bb006acb5f379adb2 106 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.7E-17 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 UA74_04405 70d3d6a38c16dc1bb006acb5f379adb2 106 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.7E-17 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 UA74_17025 84818a28f1559e50689663d071514b90 276 Pfam PF00005 ABC transporter 29 179 8.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_17025 84818a28f1559e50689663d071514b90 276 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 265 1.4E-7 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_17025 84818a28f1559e50689663d071514b90 276 SMART SM00382 37 229 1.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_17025 84818a28f1559e50689663d071514b90 276 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_17025 84818a28f1559e50689663d071514b90 276 Gene3D G3DSA:3.40.50.300 5 275 2.4E-85 T 12-10-2018 UA74_17025 84818a28f1559e50689663d071514b90 276 SUPERFAMILY SSF52540 9 251 1.02E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00150 8616244d962c0875a9bc677dd80d5bc1 478 Pfam PF13672 Protein phosphatase 2C 18 199 1.4E-11 T 12-10-2018 UA74_00150 8616244d962c0875a9bc677dd80d5bc1 478 SMART SM00332 2 233 1.6E-24 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_00150 8616244d962c0875a9bc677dd80d5bc1 478 SMART SM00331 11 235 3.0E-38 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_00150 8616244d962c0875a9bc677dd80d5bc1 478 Gene3D G3DSA:3.60.40.10 2 236 5.0E-65 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_00150 8616244d962c0875a9bc677dd80d5bc1 478 SUPERFAMILY SSF81606 4 234 3.01E-62 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_13910 b49686e5be512a2d1764307e913b4944 288 SMART SM00701 1 137 1.3E-9 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_13910 b49686e5be512a2d1764307e913b4944 288 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 24 145 4.5E-16 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_13910 b49686e5be512a2d1764307e913b4944 288 SUPERFAMILY SSF55846 2 158 4.71E-34 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_13910 b49686e5be512a2d1764307e913b4944 288 Gene3D G3DSA:3.40.80.10 1 167 1.9E-36 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_13910 b49686e5be512a2d1764307e913b4944 288 SMART SM00644 12 145 4.0E-5 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_04195 8cae01cfdcb6bc09ac1de19f07c66809 387 Gene3D G3DSA:3.60.21.10 1 271 1.2E-86 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_04195 8cae01cfdcb6bc09ac1de19f07c66809 387 SUPERFAMILY SSF56300 1 303 1.02E-53 T 12-10-2018 UA74_04195 8cae01cfdcb6bc09ac1de19f07c66809 387 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 248 4.7E-50 T 12-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 UA74_04195 8cae01cfdcb6bc09ac1de19f07c66809 387 Pfam PF00149 Calcineurin-like phosphoesterase 1 222 7.7E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UA74_04195 8cae01cfdcb6bc09ac1de19f07c66809 387 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 271 325 6.8E-7 T 12-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 SUPERFAMILY SSF48264 13 398 8.25E-100 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00385 P450 superfamily signature 270 281 4.2E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00385 P450 superfamily signature 235 252 4.2E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00385 P450 superfamily signature 338 347 4.2E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00385 P450 superfamily signature 347 358 4.2E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 Gene3D G3DSA:1.10.630.10 7 398 3.5E-132 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 Pfam PF00067 Cytochrome P450 178 368 9.1E-24 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00359 B-class P450 signature 152 167 8.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00359 B-class P450 signature 317 332 8.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00359 B-class P450 signature 135 151 8.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00359 B-class P450 signature 347 358 8.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00359 B-class P450 signature 289 316 8.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00359 B-class P450 signature 338 347 8.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00359 B-class P450 signature 88 99 8.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00359 B-class P450 signature 190 212 8.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14780 66651f846e1906c396c88a4a5e6f966d 398 PRINTS PR00359 B-class P450 signature 270 281 8.7E-58 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_10600 113ba3dc952fea3e4b359fa0bbef4b08 209 SMART SM01012 150 205 3.4E-25 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 UA74_10600 113ba3dc952fea3e4b359fa0bbef4b08 209 SUPERFAMILY SSF52172 21 205 2.56E-57 T 12-10-2018 IPR011006 CheY-like superfamily UA74_10600 113ba3dc952fea3e4b359fa0bbef4b08 209 PIRSF PIRSF036382 13 209 3.7E-74 T 12-10-2018 IPR008327 Signal transduction response regulator, antiterminator UA74_10600 113ba3dc952fea3e4b359fa0bbef4b08 209 Pfam PF00072 Response regulator receiver domain 25 134 1.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_10600 113ba3dc952fea3e4b359fa0bbef4b08 209 SMART SM00448 23 134 1.2E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_10600 113ba3dc952fea3e4b359fa0bbef4b08 209 Gene3D G3DSA:1.10.10.10 152 209 2.9E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10600 113ba3dc952fea3e4b359fa0bbef4b08 209 Gene3D G3DSA:3.40.50.2300 12 151 2.9E-36 T 12-10-2018 UA74_10600 113ba3dc952fea3e4b359fa0bbef4b08 209 Pfam PF03861 ANTAR domain 152 205 1.4E-22 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 UA74_23310 1e6c553ab7d3a956505ce3eb93458319 682 SUPERFAMILY SSF53474 6 346 2.01E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23310 1e6c553ab7d3a956505ce3eb93458319 682 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 23 274 2.5E-59 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_23310 1e6c553ab7d3a956505ce3eb93458319 682 SMART SM00939 291 557 5.0E-76 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_23310 1e6c553ab7d3a956505ce3eb93458319 682 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 20 513 7.2E-58 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 UA74_23310 1e6c553ab7d3a956505ce3eb93458319 682 Gene3D G3DSA:1.10.3020.10 154 227 7.1E-58 T 12-10-2018 UA74_23310 1e6c553ab7d3a956505ce3eb93458319 682 SUPERFAMILY SSF49785 293 538 1.38E-55 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_23310 1e6c553ab7d3a956505ce3eb93458319 682 Gene3D G3DSA:3.40.50.1820 17 306 7.1E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23310 1e6c553ab7d3a956505ce3eb93458319 682 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 316 530 1.5E-51 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_23310 1e6c553ab7d3a956505ce3eb93458319 682 Gene3D G3DSA:2.60.120.260 354 542 3.1E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_02010 4c93db9cfa34e6131f3553638e864642 225 SMART SM00448 1 120 7.4E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_02010 4c93db9cfa34e6131f3553638e864642 225 SUPERFAMILY SSF46894 136 195 2.38E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_02010 4c93db9cfa34e6131f3553638e864642 225 Pfam PF00072 Response regulator receiver domain 3 108 6.7E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_02010 4c93db9cfa34e6131f3553638e864642 225 Gene3D G3DSA:3.40.50.12740 1 202 1.4E-43 T 12-10-2018 UA74_02010 4c93db9cfa34e6131f3553638e864642 225 SMART SM00421 147 210 2.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_02010 4c93db9cfa34e6131f3553638e864642 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 195 1.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_02010 4c93db9cfa34e6131f3553638e864642 225 SUPERFAMILY SSF52172 2 136 1.28E-18 T 12-10-2018 IPR011006 CheY-like superfamily UA74_02010 4c93db9cfa34e6131f3553638e864642 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 4.9E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_02010 4c93db9cfa34e6131f3553638e864642 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 4.9E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_02010 4c93db9cfa34e6131f3553638e864642 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 4.9E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_13530 5255f4f7d9f54d404a27d5c4f4636a21 1029 Pfam PF13191 AAA ATPase domain 11 213 8.4E-12 T 12-10-2018 UA74_13530 5255f4f7d9f54d404a27d5c4f4636a21 1029 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 931 947 1.9E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_13530 5255f4f7d9f54d404a27d5c4f4636a21 1029 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 947 959 1.9E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_13530 5255f4f7d9f54d404a27d5c4f4636a21 1029 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 917 931 1.9E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_13530 5255f4f7d9f54d404a27d5c4f4636a21 1029 SUPERFAMILY SSF52540 19 251 4.2E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13530 5255f4f7d9f54d404a27d5c4f4636a21 1029 Pfam PF00196 Bacterial regulatory proteins, luxR family 916 970 1.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_13530 5255f4f7d9f54d404a27d5c4f4636a21 1029 SUPERFAMILY SSF46894 913 971 1.46E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_13530 5255f4f7d9f54d404a27d5c4f4636a21 1029 Gene3D G3DSA:1.10.10.10 863 980 2.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13530 5255f4f7d9f54d404a27d5c4f4636a21 1029 SMART SM00421 914 971 1.7E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_01390 327a97ee508ce9aec397bd6eefefb998 360 Gene3D G3DSA:3.40.50.300 118 353 1.2E-25 T 12-10-2018 UA74_01390 327a97ee508ce9aec397bd6eefefb998 360 SUPERFAMILY SSF52172 2 114 3.98E-6 T 12-10-2018 IPR011006 CheY-like superfamily UA74_01390 327a97ee508ce9aec397bd6eefefb998 360 SUPERFAMILY SSF52540 119 334 1.67E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01390 327a97ee508ce9aec397bd6eefefb998 360 Pfam PF06564 Cellulose biosynthesis protein BcsQ 120 269 4.1E-5 T 12-10-2018 IPR017746 Cellulose synthase operon protein BcsQ UA74_01390 327a97ee508ce9aec397bd6eefefb998 360 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 11 350 6.4E-101 T 12-10-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like UA74_23615 0f058f105310dd18bd7cc537581b13a1 211 SUPERFAMILY SSF46894 132 206 2.96E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_23615 0f058f105310dd18bd7cc537581b13a1 211 Gene3D G3DSA:1.10.10.10 136 205 1.7E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23615 0f058f105310dd18bd7cc537581b13a1 211 SMART SM00421 138 200 4.5E-4 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23615 0f058f105310dd18bd7cc537581b13a1 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 182 1.1E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27980 165155f37992dcc557ad80420667feac 401 SMART SM01005 251 379 4.2E-59 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 Hamap MF_01201 Alanine racemase. 9 379 30.891 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 TIGRFAM TIGR00492 alr: alanine racemase 13 371 6.1E-84 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 Pfam PF01168 Alanine racemase, N-terminal domain 16 239 2.6E-60 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 SUPERFAMILY SSF50621 246 378 1.19E-46 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_27980 165155f37992dcc557ad80420667feac 401 SUPERFAMILY SSF51419 16 252 2.62E-56 T 12-10-2018 IPR029066 PLP-binding barrel UA74_27980 165155f37992dcc557ad80420667feac 401 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 41 51 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 Gene3D G3DSA:3.20.20.10 18 234 2.0E-123 T 12-10-2018 IPR029066 PLP-binding barrel UA74_27980 165155f37992dcc557ad80420667feac 401 Pfam PF00842 Alanine racemase, C-terminal domain 251 375 3.5E-42 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 Gene3D G3DSA:2.40.37.10 16 371 2.0E-123 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_27980 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 267 282 2.2E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 36 52 2.2E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 284 299 2.2E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 72 90 2.2E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 170 181 2.2E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 212 239 2.2E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 305 322 2.2E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 133 145 2.2E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_27980 165155f37992dcc557ad80420667feac 401 PRINTS PR00992 Alanine racemase signature 360 373 2.2E-59 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_22360 45b2e73649851b1b162e715f9d5a90ee 384 Gene3D G3DSA:2.40.50.140 262 380 2.0E-39 T 12-10-2018 UA74_22360 45b2e73649851b1b162e715f9d5a90ee 384 Pfam PF04679 ATP dependent DNA ligase C terminal region 278 374 1.3E-25 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 UA74_22360 45b2e73649851b1b162e715f9d5a90ee 384 Gene3D G3DSA:3.30.1490.70 80 257 2.6E-50 T 12-10-2018 UA74_22360 45b2e73649851b1b162e715f9d5a90ee 384 SUPERFAMILY SSF56091 67 258 3.17E-41 T 12-10-2018 UA74_22360 45b2e73649851b1b162e715f9d5a90ee 384 SUPERFAMILY SSF50249 262 380 2.97E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_22360 45b2e73649851b1b162e715f9d5a90ee 384 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 70 380 1.3E-78 T 12-10-2018 IPR014146 DNA ligase D, ligase domain UA74_22360 45b2e73649851b1b162e715f9d5a90ee 384 Pfam PF01068 ATP dependent DNA ligase domain 82 258 7.9E-30 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 UA74_22360 45b2e73649851b1b162e715f9d5a90ee 384 Gene3D G3DSA:3.30.470.30 92 214 2.6E-50 T 12-10-2018 UA74_09015 3fe241a8391f1081cb3d0a3af24daa2d 419 Gene3D G3DSA:2.30.42.10 173 258 1.2E-9 T 12-10-2018 UA74_09015 3fe241a8391f1081cb3d0a3af24daa2d 419 SUPERFAMILY SSF50156 124 230 1.48E-8 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 UA74_09015 3fe241a8391f1081cb3d0a3af24daa2d 419 Pfam PF02163 Peptidase family M50 28 368 3.5E-48 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 UA74_00445 6e6935ea9723dd06e067993d347b5bf5 462 SUPERFAMILY SSF55874 254 387 2.75E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_00445 6e6935ea9723dd06e067993d347b5bf5 462 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 288 387 1.7E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_00445 6e6935ea9723dd06e067993d347b5bf5 462 Gene3D G3DSA:3.30.565.10 244 389 2.0E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_00445 6e6935ea9723dd06e067993d347b5bf5 462 Pfam PF06580 Histidine kinase 190 266 2.0E-24 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 UA74_00445 6e6935ea9723dd06e067993d347b5bf5 462 SMART SM00387 280 390 7.9E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_03775 f5e3ac92dd0165551cdb61fa9c6b119a 219 Pfam PF13559 Domain of unknown function (DUF4129) 128 197 1.8E-5 T 12-10-2018 IPR025403 Domain of unknown function DUF4129 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 3.8E-38 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 3.8E-38 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 3.8E-38 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 3.8E-38 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 Pfam PF01470 Pyroglutamyl peptidase 3 205 1.8E-64 T 12-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 Gene3D G3DSA:3.40.630.20 1 220 4.1E-73 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 PIRSF PIRSF015592 1 217 6.8E-71 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 218 5.3E-70 T 12-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 206 35.862 T 12-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 UA74_10270 dcab0edcc6be5b28b0d94b266ca1bef0 220 SUPERFAMILY SSF53182 1 219 7.06E-64 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 UA74_06050 282beb3c9896f145d7d1c78975660e54 136 Gene3D G3DSA:3.40.50.1010 7 135 3.9E-23 T 12-10-2018 UA74_06050 282beb3c9896f145d7d1c78975660e54 136 SUPERFAMILY SSF88723 9 131 5.61E-17 T 12-10-2018 IPR029060 PIN-like domain superfamily UA74_06050 282beb3c9896f145d7d1c78975660e54 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 10 134 9.93 T 12-10-2018 IPR022907 VapC family GO:0004540 UA74_06050 282beb3c9896f145d7d1c78975660e54 136 Pfam PF01850 PIN domain 10 122 1.4E-6 T 12-10-2018 IPR002716 PIN domain UA74_08280 ed754084cea5af9aeef86548d4c35ff0 789 Pfam PF03772 Competence protein 232 497 1.6E-50 T 12-10-2018 IPR004477 ComEC/Rec2-related protein UA74_08280 ed754084cea5af9aeef86548d4c35ff0 789 SMART SM00849 539 739 8.7E-6 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_08280 ed754084cea5af9aeef86548d4c35ff0 789 Pfam PF00753 Metallo-beta-lactamase superfamily 541 719 5.1E-8 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_08280 ed754084cea5af9aeef86548d4c35ff0 789 Pfam PF13567 Domain of unknown function (DUF4131) 37 180 1.6E-7 T 12-10-2018 IPR025405 Domain of unknown function DUF4131 UA74_08280 ed754084cea5af9aeef86548d4c35ff0 789 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 254 423 6.5E-17 T 12-10-2018 IPR004477 ComEC/Rec2-related protein UA74_08280 ed754084cea5af9aeef86548d4c35ff0 789 SUPERFAMILY SSF56281 526 777 4.32E-39 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_08280 ed754084cea5af9aeef86548d4c35ff0 789 Gene3D G3DSA:3.60.15.10 528 783 1.4E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_14170 4f38fc9fc26c9fb20c12ccf12c01f721 265 SUPERFAMILY SSF51621 7 259 6.73E-47 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UA74_14170 4f38fc9fc26c9fb20c12ccf12c01f721 265 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 240 2.0E-63 T 12-10-2018 UA74_14170 4f38fc9fc26c9fb20c12ccf12c01f721 265 Gene3D G3DSA:3.20.20.60 1 264 8.4E-58 T 12-10-2018 UA74_21510 c2cd35c7de6db3bdcc7f7c8ee48e2367 426 Pfam PF01757 Acyltransferase family 10 346 4.0E-10 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_02705 0502a68dd222f204f89ccfa612421c46 301 Gene3D G3DSA:3.30.200.20 1 87 2.8E-22 T 12-10-2018 UA74_02705 0502a68dd222f204f89ccfa612421c46 301 SUPERFAMILY SSF56112 5 260 1.75E-65 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_02705 0502a68dd222f204f89ccfa612421c46 301 Pfam PF00069 Protein kinase domain 13 255 7.5E-40 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_02705 0502a68dd222f204f89ccfa612421c46 301 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_02705 0502a68dd222f204f89ccfa612421c46 301 SMART SM00220 7 266 1.3E-45 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_02705 0502a68dd222f204f89ccfa612421c46 301 Gene3D G3DSA:1.10.510.10 89 268 7.0E-44 T 12-10-2018 UA74_02705 0502a68dd222f204f89ccfa612421c46 301 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 14 37 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_23840 feb442cabbd1bed57f26782767ff4b41 500 SUPERFAMILY SSF53067 265 485 1.84E-35 T 12-10-2018 UA74_23840 feb442cabbd1bed57f26782767ff4b41 500 Gene3D G3DSA:3.30.420.40 11 250 1.4E-79 T 12-10-2018 UA74_23840 feb442cabbd1bed57f26782767ff4b41 500 Gene3D G3DSA:3.30.420.40 251 498 1.1E-97 T 12-10-2018 UA74_23840 feb442cabbd1bed57f26782767ff4b41 500 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 268 458 4.9E-37 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UA74_23840 feb442cabbd1bed57f26782767ff4b41 500 SUPERFAMILY SSF53067 16 259 1.62E-43 T 12-10-2018 UA74_23840 feb442cabbd1bed57f26782767ff4b41 500 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 17 257 1.8E-28 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 Gene3D G3DSA:3.40.50.12740 3 215 1.5E-69 T 12-10-2018 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 SUPERFAMILY SSF52172 1 133 7.54E-34 T 12-10-2018 IPR011006 CheY-like superfamily UA74_06065 578c31840d518abfcd869a94408b2cd2 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.9E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 SUPERFAMILY SSF46894 144 215 2.04E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 Pfam PF00072 Response regulator receiver domain 5 118 3.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 SMART SM00448 3 118 1.9E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_06065 578c31840d518abfcd869a94408b2cd2 216 SMART SM00421 152 209 1.4E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17730 c98be6cc67d4cfe82b482140efa6383b 248 Gene3D G3DSA:3.40.50.360 14 218 4.0E-29 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_17730 c98be6cc67d4cfe82b482140efa6383b 248 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 16 223 19.594 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 UA74_17730 c98be6cc67d4cfe82b482140efa6383b 248 Pfam PF02525 Flavodoxin-like fold 16 201 1.0E-21 T 12-10-2018 IPR003680 Flavodoxin-like fold UA74_17730 c98be6cc67d4cfe82b482140efa6383b 248 SUPERFAMILY SSF52218 16 200 2.56E-24 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_26210 a139623c32838b438cca40620003a032 142 Gene3D G3DSA:3.30.350.10 34 142 2.4E-31 T 12-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 UA74_26210 a139623c32838b438cca40620003a032 142 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 42 132 2.0E-11 T 12-10-2018 IPR023549 Subtilisin inhibitor GO:0004867 UA74_26210 a139623c32838b438cca40620003a032 142 Pfam PF00720 Subtilisin inhibitor-like 39 128 3.3E-21 T 12-10-2018 IPR023549 Subtilisin inhibitor GO:0004867 UA74_26210 a139623c32838b438cca40620003a032 142 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 67 94 9.0E-9 T 12-10-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 UA74_26210 a139623c32838b438cca40620003a032 142 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 117 133 9.0E-9 T 12-10-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 UA74_26210 a139623c32838b438cca40620003a032 142 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 41 67 9.0E-9 T 12-10-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 UA74_26210 a139623c32838b438cca40620003a032 142 SUPERFAMILY SSF55399 39 142 5.23E-25 T 12-10-2018 IPR036819 Subtilisin inhibitor-like superfamily GO:0004867 UA74_15130 4af33973d96b27186f614c2f0952d363 544 Pfam PF02310 B12 binding domain 37 147 5.4E-17 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_15130 4af33973d96b27186f614c2f0952d363 544 Gene3D G3DSA:3.80.30.20 200 368 6.0E-13 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UA74_15130 4af33973d96b27186f614c2f0952d363 544 SUPERFAMILY SSF52242 40 141 2.83E-5 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_15130 4af33973d96b27186f614c2f0952d363 544 Gene3D G3DSA:3.40.50.280 54 154 2.6E-7 T 12-10-2018 UA74_15130 4af33973d96b27186f614c2f0952d363 544 SUPERFAMILY SSF102114 175 360 6.8E-21 T 12-10-2018 UA74_15130 4af33973d96b27186f614c2f0952d363 544 Pfam PF04055 Radical SAM superfamily 207 351 3.2E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_15130 4af33973d96b27186f614c2f0952d363 544 SMART SM00729 202 408 3.6E-6 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_19670 c5b4ba9aab5747c4f328332f7ce12c9b 425 Pfam PF03069 Acetamidase/Formamidase family 265 410 3.8E-18 T 12-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 UA74_19670 c5b4ba9aab5747c4f328332f7ce12c9b 425 Pfam PF03069 Acetamidase/Formamidase family 152 256 1.8E-5 T 12-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 UA74_19670 c5b4ba9aab5747c4f328332f7ce12c9b 425 Gene3D G3DSA:3.10.28.20 340 425 3.6E-13 T 12-10-2018 UA74_19670 c5b4ba9aab5747c4f328332f7ce12c9b 425 SUPERFAMILY SSF141130 77 425 1.05E-73 T 12-10-2018 UA74_19670 c5b4ba9aab5747c4f328332f7ce12c9b 425 Gene3D G3DSA:2.60.120.580 85 223 7.1E-13 T 12-10-2018 UA74_19670 c5b4ba9aab5747c4f328332f7ce12c9b 425 Gene3D G3DSA:2.60.120.580 224 330 9.2E-28 T 12-10-2018 UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 Gene3D G3DSA:1.10.940.10 29 170 1.7E-40 T 12-10-2018 IPR035926 NusB-like superfamily UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 292 302 8.4E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 259 273 8.4E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 406 422 8.4E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 457 474 8.4E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 356 368 8.4E-18 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 SUPERFAMILY SSF48013 32 186 4.84E-33 T 12-10-2018 IPR035926 NusB-like superfamily UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 Gene3D G3DSA:3.40.50.150 178 474 4.5E-53 T 12-10-2018 UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 Pfam PF01189 16S rRNA methyltransferase RsmB/F 290 472 2.7E-45 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 Pfam PF01029 NusB family 32 154 1.2E-26 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 SUPERFAMILY SSF53335 176 474 1.4E-50 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_12270 346be5e857d01d43dc2f81fc1c0a5444 480 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 355 366 - T 12-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 Gene3D G3DSA:3.40.50.620 32 529 5.6E-291 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_08125 5eb04706ff6265183bba0fee1842151c 882 TIGRFAM TIGR00422 valS: valine--tRNA ligase 13 852 1.7E-301 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 SUPERFAMILY SSF50677 200 342 3.66E-54 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 46 57 3.9E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 3.9E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 238 255 3.9E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 479 497 3.9E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 PRINTS PR00986 Valyl-tRNA synthetase signature 354 367 3.9E-38 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 Gene3D G3DSA:1.10.730.10 12 742 5.6E-291 T 12-10-2018 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 Pfam PF08264 Anticodon-binding domain of tRNA 610 752 1.0E-37 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 810 874 1.7E-18 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 SUPERFAMILY SSF46589 810 874 4.81E-13 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 Gene3D G3DSA:3.90.740.10 185 350 5.6E-291 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 25 433 6.7E-144 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 445 565 1.3E-46 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 53 64 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 Gene3D G3DSA:1.10.287.380 803 875 3.5E-16 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 SUPERFAMILY SSF47323 580 822 5.05E-47 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 SUPERFAMILY SSF52374 3 577 3.03E-134 T 12-10-2018 UA74_08125 5eb04706ff6265183bba0fee1842151c 882 Hamap MF_02004 Valine--tRNA ligase [valS]. 12 875 15.07 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_30020 3a5c56e6e42c2e7757fdcb0423f03618 151 Gene3D G3DSA:3.10.430.100 60 150 1.0E-21 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily UA74_30020 3a5c56e6e42c2e7757fdcb0423f03618 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 2.7E-21 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30020 3a5c56e6e42c2e7757fdcb0423f03618 151 SUPERFAMILY SSF55658 1 55 4.71E-17 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal UA74_30020 3a5c56e6e42c2e7757fdcb0423f03618 151 Gene3D G3DSA:3.40.5.10 1 59 2.4E-21 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30020 3a5c56e6e42c2e7757fdcb0423f03618 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 4.0E-34 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_30020 3a5c56e6e42c2e7757fdcb0423f03618 151 SUPERFAMILY SSF55653 58 148 3.27E-21 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily UA74_30020 3a5c56e6e42c2e7757fdcb0423f03618 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 7.0E-23 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal UA74_30020 3a5c56e6e42c2e7757fdcb0423f03618 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 24.923 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_30020 3a5c56e6e42c2e7757fdcb0423f03618 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02840 d119e23912e9787937d34a911a6cf691 239 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 4.0E-100 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 UA74_02840 d119e23912e9787937d34a911a6cf691 239 SUPERFAMILY SSF56808 6 227 2.35E-80 T 12-10-2018 IPR023674 Ribosomal protein L1-like UA74_02840 d119e23912e9787937d34a911a6cf691 239 PIRSF PIRSF002155 1 227 2.1E-73 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02840 d119e23912e9787937d34a911a6cf691 239 Gene3D G3DSA:3.40.50.790 68 159 6.1E-80 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich UA74_02840 d119e23912e9787937d34a911a6cf691 239 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.63 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 UA74_02840 d119e23912e9787937d34a911a6cf691 239 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02840 d119e23912e9787937d34a911a6cf691 239 Pfam PF00687 Ribosomal protein L1p/L10e family 32 220 2.0E-50 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein UA74_02840 d119e23912e9787937d34a911a6cf691 239 Gene3D G3DSA:3.30.190.20 24 225 6.1E-80 T 12-10-2018 UA74_21890 a4693f78cea3a38e680667c159cf5f7e 543 SUPERFAMILY SSF56300 95 475 7.05E-11 T 12-10-2018 UA74_21890 a4693f78cea3a38e680667c159cf5f7e 543 Gene3D G3DSA:3.60.21.70 119 458 4.8E-15 T 12-10-2018 IPR038607 PhoD-like superfamily UA74_21890 a4693f78cea3a38e680667c159cf5f7e 543 Pfam PF09423 PhoD-like phosphatase 122 456 1.6E-12 T 12-10-2018 IPR018946 Alkaline phosphatase D-related UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 SUPERFAMILY SSF51905 1 290 5.96E-23 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 275 2.4E-32 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 Gene3D G3DSA:3.50.50.100 1 339 1.1E-57 T 12-10-2018 UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.5E-11 T 12-10-2018 UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 90 108 1.5E-11 T 12-10-2018 UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.5E-11 T 12-10-2018 UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 151 3.6E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 299 3.6E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 3.6E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_06945 68ad6c8fdc6a37fd61fabb3c9cff3ed4 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 91 99 3.6E-8 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_08915 864db4b7f343056c580fdfab09f3a52c 385 SUPERFAMILY SSF102405 106 299 1.98E-35 T 12-10-2018 UA74_08915 864db4b7f343056c580fdfab09f3a52c 385 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 293 2.8E-63 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 UA74_08915 864db4b7f343056c580fdfab09f3a52c 385 Gene3D G3DSA:3.40.50.450 7 304 2.6E-88 T 12-10-2018 UA74_08915 864db4b7f343056c580fdfab09f3a52c 385 Pfam PF02481 DNA recombination-mediator protein A 74 292 1.2E-69 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 UA74_13205 bb6dd769c853c122cd77c626d74a2c79 810 Gene3D G3DSA:3.40.50.300 550 789 7.6E-59 T 12-10-2018 UA74_13205 bb6dd769c853c122cd77c626d74a2c79 810 SMART SM00382 580 763 2.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13205 bb6dd769c853c122cd77c626d74a2c79 810 SUPERFAMILY SSF90123 126 413 9.42E-28 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13205 bb6dd769c853c122cd77c626d74a2c79 810 Gene3D G3DSA:1.20.1560.10 107 431 3.7E-18 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13205 bb6dd769c853c122cd77c626d74a2c79 810 Pfam PF00005 ABC transporter 572 719 4.4E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13205 bb6dd769c853c122cd77c626d74a2c79 810 SUPERFAMILY SSF52540 554 785 5.33E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13205 bb6dd769c853c122cd77c626d74a2c79 810 ProSitePatterns PS00211 ABC transporters family signature. 691 705 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 Gene3D G3DSA:2.40.10.10 181 274 1.7E-22 T 12-10-2018 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 Pfam PF13365 Trypsin-like peptidase domain 210 354 4.3E-32 T 12-10-2018 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 SUPERFAMILY SSF50494 184 404 1.85E-51 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 PRINTS PR00834 HtrA/DegQ protease family signature 219 231 2.1E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 PRINTS PR00834 HtrA/DegQ protease family signature 347 364 2.1E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 2.1E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 PRINTS PR00834 HtrA/DegQ protease family signature 325 342 2.1E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 PRINTS PR00834 HtrA/DegQ protease family signature 431 443 2.1E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 PRINTS PR00834 HtrA/DegQ protease family signature 285 309 2.1E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 SMART SM00228 399 473 2.6E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 SUPERFAMILY SSF50156 370 484 4.73E-16 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 Pfam PF13180 PDZ domain 400 482 2.3E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 Gene3D G3DSA:2.30.42.10 397 488 2.7E-18 T 12-10-2018 UA74_04590 bed5274e270c3f0765153a8d89935ecd 488 Gene3D G3DSA:2.40.10.10 276 396 1.8E-39 T 12-10-2018 UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 2.2E-54 T 12-10-2018 UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 SUPERFAMILY SSF51735 2 248 2.15E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 210 3.2E-4 T 12-10-2018 UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.3E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.3E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.3E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.3E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.3E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.3E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08430 fe5f725771ca88f60113cd517ba72f41 248 Gene3D G3DSA:3.40.50.720 1 247 1.5E-74 T 12-10-2018 UA74_17330 559a7edbf94bba04ad2dbb66f0314c57 277 Pfam PF13560 Helix-turn-helix domain 6 86 3.0E-16 T 12-10-2018 UA74_17330 559a7edbf94bba04ad2dbb66f0314c57 277 SMART SM00530 10 83 1.1E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_17330 559a7edbf94bba04ad2dbb66f0314c57 277 Gene3D G3DSA:3.30.450.180 106 271 2.7E-10 T 12-10-2018 UA74_17330 559a7edbf94bba04ad2dbb66f0314c57 277 SUPERFAMILY SSF47413 31 80 4.15E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_17330 559a7edbf94bba04ad2dbb66f0314c57 277 Gene3D G3DSA:1.10.260.40 6 87 5.7E-10 T 12-10-2018 UA74_06455 3307617e76c43ea431ffcd8093149166 357 Pfam PF00891 O-methyltransferase 107 320 3.2E-42 T 12-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_06455 3307617e76c43ea431ffcd8093149166 357 Gene3D G3DSA:3.40.50.150 96 327 1.5E-62 T 12-10-2018 UA74_06455 3307617e76c43ea431ffcd8093149166 357 SUPERFAMILY SSF46785 15 87 9.53E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_06455 3307617e76c43ea431ffcd8093149166 357 PIRSF PIRSF005739 8 325 1.6E-37 T 12-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_06455 3307617e76c43ea431ffcd8093149166 357 SUPERFAMILY SSF53335 107 321 2.34E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_06455 3307617e76c43ea431ffcd8093149166 357 Gene3D G3DSA:1.10.10.10 3 95 4.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 50 61 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 Gene3D G3DSA:3.40.50.620 28 582 3.9E-188 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 124 619 2.0E-67 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 104 8.8E-19 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 Gene3D G3DSA:1.10.730.10 17 769 3.9E-188 T 12-10-2018 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 SUPERFAMILY SSF47323 633 861 5.98E-31 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 Pfam PF08264 Anticodon-binding domain of tRNA 658 824 3.9E-26 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 PRINTS PR00986 Valyl-tRNA synthetase signature 386 399 7.5E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 PRINTS PR00986 Valyl-tRNA synthetase signature 257 274 7.5E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 PRINTS PR00986 Valyl-tRNA synthetase signature 43 54 7.5E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 PRINTS PR00986 Valyl-tRNA synthetase signature 502 523 7.5E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 PRINTS PR00986 Valyl-tRNA synthetase signature 533 551 7.5E-20 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 Gene3D G3DSA:3.90.740.10 203 382 3.9E-188 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 Hamap MF_02005 Valine--tRNA ligase [valS]. 8 855 27.915 T 12-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 SUPERFAMILY SSF50677 220 369 3.14E-31 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_20800 e037db2cf47a6aa5fde53b264d36efd2 873 SUPERFAMILY SSF52374 7 624 1.79E-107 T 12-10-2018 UA74_14385 0dc22c88cf6cbfaa99cba65eaaa18de9 308 SUPERFAMILY SSF47413 35 86 5.33E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_14385 0dc22c88cf6cbfaa99cba65eaaa18de9 308 Gene3D G3DSA:1.10.260.40 30 102 6.1E-9 T 12-10-2018 UA74_14385 0dc22c88cf6cbfaa99cba65eaaa18de9 308 SMART SM00530 15 87 1.1E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_14385 0dc22c88cf6cbfaa99cba65eaaa18de9 308 Gene3D G3DSA:3.30.450.180 110 278 1.8E-16 T 12-10-2018 UA74_14385 0dc22c88cf6cbfaa99cba65eaaa18de9 308 Pfam PF13560 Helix-turn-helix domain 11 90 4.2E-18 T 12-10-2018 UA74_04390 ce6ba490596ef0968a5e42c6ad5e1e22 354 Pfam PF00005 ABC transporter 54 205 1.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_04390 ce6ba490596ef0968a5e42c6ad5e1e22 354 ProSitePatterns PS00211 ABC transporters family signature. 178 192 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_04390 ce6ba490596ef0968a5e42c6ad5e1e22 354 Gene3D G3DSA:3.40.50.300 23 351 3.9E-102 T 12-10-2018 UA74_04390 ce6ba490596ef0968a5e42c6ad5e1e22 354 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 257 324 7.1E-16 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_04390 ce6ba490596ef0968a5e42c6ad5e1e22 354 SMART SM00382 62 255 1.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_04390 ce6ba490596ef0968a5e42c6ad5e1e22 354 SUPERFAMILY SSF52540 25 277 7.43E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04390 ce6ba490596ef0968a5e42c6ad5e1e22 354 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 255 345 1.4E-25 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_17610 0cddab9e1fd82d46e9747919ffb492de 393 PIRSF PIRSF016578 2 393 2.5E-116 T 12-10-2018 UA74_17610 0cddab9e1fd82d46e9747919ffb492de 393 SUPERFAMILY SSF47203 237 380 2.09E-10 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_17610 0cddab9e1fd82d46e9747919ffb492de 393 Gene3D G3DSA:1.10.540.10 3 113 3.4E-26 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_17610 0cddab9e1fd82d46e9747919ffb492de 393 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 242 371 3.9E-20 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain UA74_17610 0cddab9e1fd82d46e9747919ffb492de 393 SUPERFAMILY SSF56645 9 208 1.83E-31 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_17610 0cddab9e1fd82d46e9747919ffb492de 393 Gene3D G3DSA:2.40.110.10 114 207 9.8E-26 T 12-10-2018 UA74_17610 0cddab9e1fd82d46e9747919ffb492de 393 Gene3D G3DSA:1.20.140.10 213 392 1.2E-31 T 12-10-2018 UA74_17610 0cddab9e1fd82d46e9747919ffb492de 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 88 2.0E-4 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UA74_15450 d842535fa4c59966418862a6e8b4d24c 316 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 43 294 2.3E-67 T 12-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 UA74_15450 d842535fa4c59966418862a6e8b4d24c 316 SUPERFAMILY SSF56112 38 296 2.72E-27 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_15450 d842535fa4c59966418862a6e8b4d24c 316 Gene3D G3DSA:3.90.1200.10 152 263 3.0E-5 T 12-10-2018 UA74_08725 97b4208af97d28813d7fd011285d0aab 320 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 315 4.5E-118 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 UA74_08725 97b4208af97d28813d7fd011285d0aab 320 Gene3D G3DSA:3.90.25.10 170 299 3.1E-116 T 12-10-2018 UA74_08725 97b4208af97d28813d7fd011285d0aab 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 246 6.9E-58 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_08725 97b4208af97d28813d7fd011285d0aab 320 SUPERFAMILY SSF51735 2 314 2.05E-88 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_08725 97b4208af97d28813d7fd011285d0aab 320 Gene3D G3DSA:3.40.50.720 4 246 3.1E-116 T 12-10-2018 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 6 194 3.8E-35 T 12-10-2018 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 161 185 1.0E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 1.0E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 122 130 1.0E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 PIRSF PIRSF000332 206 293 0.029 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 PIRSF PIRSF000332 1 229 2.0E-20 T 12-10-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 Gene3D G3DSA:3.50.50.60 1 351 7.7E-100 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 SUPERFAMILY SSF51905 124 318 1.3E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 1.1E-11 T 12-10-2018 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-11 T 12-10-2018 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 1.1E-11 T 12-10-2018 UA74_19485 9211c8bd574f9b8f4f22f49f9122ec7a 357 SUPERFAMILY SSF51905 1 185 8.74E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_21640 6dabae294d002341da463af1920fb971 345 SUPERFAMILY SSF54427 205 316 3.0E-15 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_21640 6dabae294d002341da463af1920fb971 345 Gene3D G3DSA:1.10.1740.10 7 90 3.2E-22 T 12-10-2018 UA74_21640 6dabae294d002341da463af1920fb971 345 Gene3D G3DSA:1.10.10.10 123 196 2.4E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21640 6dabae294d002341da463af1920fb971 345 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 18 324 8.0E-111 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria UA74_21640 6dabae294d002341da463af1920fb971 345 Pfam PF12680 SnoaL-like domain 214 295 7.4E-7 T 12-10-2018 IPR037401 SnoaL-like domain UA74_21640 6dabae294d002341da463af1920fb971 345 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 43 74 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_21640 6dabae294d002341da463af1920fb971 345 SUPERFAMILY SSF88946 17 91 4.71E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_21640 6dabae294d002341da463af1920fb971 345 Pfam PF04542 Sigma-70 region 2 22 88 6.0E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_21640 6dabae294d002341da463af1920fb971 345 Pfam PF08281 Sigma-70, region 4 137 190 2.2E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_21640 6dabae294d002341da463af1920fb971 345 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 191 2.0E-22 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_21640 6dabae294d002341da463af1920fb971 345 Gene3D G3DSA:3.10.450.50 202 320 9.5E-13 T 12-10-2018 UA74_21640 6dabae294d002341da463af1920fb971 345 SUPERFAMILY SSF88659 105 193 5.05E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_29835 cc4a2850c0bb57bf852cf9b39d480832 199 Gene3D G3DSA:1.10.357.10 6 198 2.8E-47 T 12-10-2018 UA74_29835 cc4a2850c0bb57bf852cf9b39d480832 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 2.2E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_29835 cc4a2850c0bb57bf852cf9b39d480832 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.2E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_29835 cc4a2850c0bb57bf852cf9b39d480832 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.2E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_29835 cc4a2850c0bb57bf852cf9b39d480832 199 SUPERFAMILY SSF46689 7 90 9.23E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_29535 85b0cf44e9c3572efcf04b2f099d3d6e 305 Gene3D G3DSA:3.90.1230.10 169 275 4.1E-93 T 12-10-2018 UA74_29535 85b0cf44e9c3572efcf04b2f099d3d6e 305 Gene3D G3DSA:3.90.340.10 2 293 4.1E-93 T 12-10-2018 UA74_29535 85b0cf44e9c3572efcf04b2f099d3d6e 305 SUPERFAMILY SSF56512 2 296 1.09E-94 T 12-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_29535 85b0cf44e9c3572efcf04b2f099d3d6e 305 Gene3D G3DSA:3.90.440.10 55 168 4.1E-93 T 12-10-2018 UA74_29535 85b0cf44e9c3572efcf04b2f099d3d6e 305 Pfam PF02898 Nitric oxide synthase, oxygenase domain 2 290 5.3E-91 T 12-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 SMART SM00382 30 240 6.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 SMART SM00382 346 516 1.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 Gene3D G3DSA:3.40.50.300 2 282 3.2E-72 T 12-10-2018 UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 Gene3D G3DSA:3.40.50.300 284 556 4.8E-62 T 12-10-2018 UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 Pfam PF12848 ABC transporter 227 303 5.2E-14 T 12-10-2018 IPR032781 ABC-transporter extension domain UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 Pfam PF00005 ABC transporter 338 471 5.3E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 SUPERFAMILY SSF52540 307 507 1.64E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 SUPERFAMILY SSF52540 8 241 3.29E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 Pfam PF00005 ABC transporter 21 188 9.8E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_07860 812da9e5addc815d2ec8c1fb4a875b09 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 555 1.1E-264 T 12-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 UA74_14890 8477dbd8c2c7abde02df724f34255617 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 2.9E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_14890 8477dbd8c2c7abde02df724f34255617 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 135 147 2.9E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_14890 8477dbd8c2c7abde02df724f34255617 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 2.9E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_14890 8477dbd8c2c7abde02df724f34255617 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 2.9E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_14890 8477dbd8c2c7abde02df724f34255617 351 Gene3D G3DSA:3.50.50.60 8 307 1.6E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_14890 8477dbd8c2c7abde02df724f34255617 351 SUPERFAMILY SSF51905 5 310 3.89E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_14890 8477dbd8c2c7abde02df724f34255617 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 6.2E-13 T 12-10-2018 UA74_14890 8477dbd8c2c7abde02df724f34255617 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 6.2E-13 T 12-10-2018 UA74_14890 8477dbd8c2c7abde02df724f34255617 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 6.2E-13 T 12-10-2018 UA74_14890 8477dbd8c2c7abde02df724f34255617 351 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 290 1.0E-18 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_14890 8477dbd8c2c7abde02df724f34255617 351 Gene3D G3DSA:3.50.50.60 126 237 1.6E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 51 276 2.7E-34 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 Gene3D G3DSA:1.10.1740.10 31 123 1.6E-30 T 12-10-2018 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 Gene3D G3DSA:1.20.140.160 125 280 2.8E-46 T 12-10-2018 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 PIRSF PIRSF000770 29 280 7.8E-55 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 Pfam PF04539 Sigma-70 region 3 135 210 8.6E-7 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 54 276 1.2E-83 T 12-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 SUPERFAMILY SSF88659 127 204 1.96E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 Pfam PF04545 Sigma-70, region 4 225 274 1.1E-16 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 81 94 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 SUPERFAMILY SSF88946 29 126 1.31E-27 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 Pfam PF04542 Sigma-70 region 2 54 126 4.6E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 246 272 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 PRINTS PR00046 Major sigma-70 factor signature 229 241 1.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 PRINTS PR00046 Major sigma-70 factor signature 246 261 1.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 PRINTS PR00046 Major sigma-70 factor signature 261 272 1.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 PRINTS PR00046 Major sigma-70 factor signature 81 94 1.7E-12 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08925 586531d2b1c06cd9fa4a1b7885b774fe 280 SUPERFAMILY SSF88659 193 278 8.97E-22 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_19990 2d795d173f97328b744ee076d06612e1 287 Gene3D G3DSA:3.40.50.720 4 180 5.2E-56 T 12-10-2018 UA74_19990 2d795d173f97328b744ee076d06612e1 287 Gene3D G3DSA:1.10.3640.10 181 281 3.8E-32 T 12-10-2018 IPR037161 Semialdehyde dehydrogenase-like, C-terminal UA74_19990 2d795d173f97328b744ee076d06612e1 287 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 10 95 6.2E-7 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UA74_19990 2d795d173f97328b744ee076d06612e1 287 SUPERFAMILY SSF51735 10 174 5.88E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_19990 2d795d173f97328b744ee076d06612e1 287 Pfam PF16896 Phosphogluconate dehydrogenase (decarboxylating) C-term 128 281 2.3E-62 T 12-10-2018 IPR031663 Phosphogluconate dehydrogenase (decarboxylating) , C-terminal UA74_22725 550c6de4acbb3f333627ab1fcf99968b 430 Gene3D G3DSA:3.40.1190.20 4 117 3.6E-27 T 12-10-2018 IPR029056 Ribokinase-like UA74_22725 550c6de4acbb3f333627ab1fcf99968b 430 Gene3D G3DSA:3.40.1190.20 183 415 1.5E-50 T 12-10-2018 IPR029056 Ribokinase-like UA74_22725 550c6de4acbb3f333627ab1fcf99968b 430 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 353 366 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_22725 550c6de4acbb3f333627ab1fcf99968b 430 SUPERFAMILY SSF53613 200 409 8.57E-45 T 12-10-2018 IPR029056 Ribokinase-like UA74_22725 550c6de4acbb3f333627ab1fcf99968b 430 SUPERFAMILY SSF53613 8 101 4.28E-18 T 12-10-2018 IPR029056 Ribokinase-like UA74_22725 550c6de4acbb3f333627ab1fcf99968b 430 Pfam PF00294 pfkB family carbohydrate kinase 210 396 4.2E-29 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_22725 550c6de4acbb3f333627ab1fcf99968b 430 Pfam PF00294 pfkB family carbohydrate kinase 10 99 1.9E-14 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_25185 38817a5662f01992c6e60fb55c4eaf04 294 Gene3D G3DSA:3.40.50.1980 6 125 8.9E-19 T 12-10-2018 UA74_25185 38817a5662f01992c6e60fb55c4eaf04 294 SUPERFAMILY SSF53807 17 265 1.96E-25 T 12-10-2018 UA74_25185 38817a5662f01992c6e60fb55c4eaf04 294 Gene3D G3DSA:3.40.50.1980 138 266 3.3E-6 T 12-10-2018 UA74_22120 7c69ec136acf76630a823def200d5db9 712 Gene3D G3DSA:3.40.50.1820 26 387 2.9E-76 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22120 7c69ec136acf76630a823def200d5db9 712 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 233 263 - T 12-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 UA74_22120 7c69ec136acf76630a823def200d5db9 712 Gene3D G3DSA:3.40.50.1820 504 699 1.7E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22120 7c69ec136acf76630a823def200d5db9 712 SUPERFAMILY SSF53474 102 387 2.68E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22120 7c69ec136acf76630a823def200d5db9 712 Pfam PF05448 Acetyl xylan esterase (AXE1) 174 279 1.8E-8 T 12-10-2018 IPR008391 Acetyl xylan esterase UA74_22120 7c69ec136acf76630a823def200d5db9 712 SUPERFAMILY SSF53474 521 667 2.07E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26440 caeec372e2dab4610d74aaa8d12d40ce 212 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 191 1.2E-27 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_26440 caeec372e2dab4610d74aaa8d12d40ce 212 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 51 82 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_26440 caeec372e2dab4610d74aaa8d12d40ce 212 SUPERFAMILY SSF88659 135 193 2.06E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_26440 caeec372e2dab4610d74aaa8d12d40ce 212 Pfam PF08281 Sigma-70, region 4 137 188 5.5E-17 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_26440 caeec372e2dab4610d74aaa8d12d40ce 212 SUPERFAMILY SSF88946 26 109 4.19E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_26440 caeec372e2dab4610d74aaa8d12d40ce 212 Pfam PF04542 Sigma-70 region 2 33 96 1.2E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_26440 caeec372e2dab4610d74aaa8d12d40ce 212 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 20 204 6.9E-107 T 12-10-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_26440 caeec372e2dab4610d74aaa8d12d40ce 212 Gene3D G3DSA:1.10.10.10 129 197 9.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26440 caeec372e2dab4610d74aaa8d12d40ce 212 Gene3D G3DSA:1.10.1740.10 17 99 4.2E-34 T 12-10-2018 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 1.5E-14 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 3.7E-67 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 2.2E-243 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 Gene3D G3DSA:3.40.50.300 97 382 1.2E-113 T 12-10-2018 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 SUPERFAMILY SSF50615 14 97 8.37E-25 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 SUPERFAMILY SSF52540 99 381 3.72E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 SUPERFAMILY SSF47917 383 511 1.54E-44 T 12-10-2018 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 48.646 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 Gene3D G3DSA:1.20.150.20 383 513 6.0E-49 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 Gene3D G3DSA:2.40.30.20 4 96 1.9E-29 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07055 8d2a8b60473d6bc87cfe77899a7e0365 549 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 2.9E-46 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_25805 0be0030659aeb141792d9592f052d85b 380 PIRSF PIRSF001434 3 378 2.2E-97 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_25805 0be0030659aeb141792d9592f052d85b 380 SUPERFAMILY SSF53383 33 377 3.57E-70 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_25805 0be0030659aeb141792d9592f052d85b 380 Gene3D G3DSA:3.40.640.10 8 255 3.9E-59 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_25805 0be0030659aeb141792d9592f052d85b 380 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 375 4.6E-75 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_25805 0be0030659aeb141792d9592f052d85b 380 Gene3D G3DSA:3.90.1150.10 256 379 1.3E-26 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_20500 bc1b998e32369b37520853017afb0e24 224 Gene3D G3DSA:3.60.20.10 1 212 5.3E-55 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_20500 bc1b998e32369b37520853017afb0e24 224 SUPERFAMILY SSF56235 1 223 7.25E-64 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_20500 bc1b998e32369b37520853017afb0e24 224 Pfam PF06267 Family of unknown function (DUF1028) 2 191 8.5E-55 T 12-10-2018 IPR010430 Protein of unknown function DUF1028 UA74_08420 20300e241d23fff174b71dd5b3be3e97 387 Gene3D G3DSA:3.30.420.40 206 363 4.4E-70 T 12-10-2018 UA74_08420 20300e241d23fff174b71dd5b3be3e97 387 SUPERFAMILY SSF53067 84 381 1.35E-43 T 12-10-2018 UA74_08420 20300e241d23fff174b71dd5b3be3e97 387 Gene3D G3DSA:3.30.420.40 85 376 4.4E-70 T 12-10-2018 UA74_08420 20300e241d23fff174b71dd5b3be3e97 387 Gene3D G3DSA:1.10.10.10 3 76 1.4E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08420 20300e241d23fff174b71dd5b3be3e97 387 Pfam PF00480 ROK family 85 379 2.5E-49 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_08420 20300e241d23fff174b71dd5b3be3e97 387 SUPERFAMILY SSF46785 10 74 2.15E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_03040 e8e8b41f9c6cb6b03b6274329e2ddb13 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 144 7.3E-43 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03040 e8e8b41f9c6cb6b03b6274329e2ddb13 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 141 - T 12-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03040 e8e8b41f9c6cb6b03b6274329e2ddb13 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 145 2.1E-30 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P UA74_03040 e8e8b41f9c6cb6b03b6274329e2ddb13 147 SUPERFAMILY SSF52080 8 146 5.49E-39 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily UA74_03040 e8e8b41f9c6cb6b03b6274329e2ddb13 147 Gene3D G3DSA:3.100.10.10 67 147 2.5E-21 T 12-10-2018 UA74_03040 e8e8b41f9c6cb6b03b6274329e2ddb13 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 147 19.069 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 UA74_13335 cabdc332dda932994a9e53c80b491743 253 Gene3D G3DSA:3.40.50.720 2 249 1.6E-75 T 12-10-2018 UA74_13335 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13335 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13335 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13335 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13335 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13335 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13335 cabdc332dda932994a9e53c80b491743 253 SUPERFAMILY SSF51735 10 248 4.79E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_13335 cabdc332dda932994a9e53c80b491743 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 200 0.0023 T 12-10-2018 UA74_13335 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 5.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13335 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 5.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13335 cabdc332dda932994a9e53c80b491743 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 5.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13335 cabdc332dda932994a9e53c80b491743 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 247 3.9E-62 T 12-10-2018 UA74_13335 cabdc332dda932994a9e53c80b491743 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 9.1E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 9.1E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 78 9.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 Gene3D G3DSA:1.10.357.10 84 247 2.5E-34 T 12-10-2018 UA74_00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 93 245 1.0E-11 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 SUPERFAMILY SSF48498 96 247 8.89E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 SUPERFAMILY SSF46689 23 84 9.98E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_00075 7dea6075aaf1ced1d4a773f6b7612e8a 253 Gene3D G3DSA:1.10.10.60 8 83 1.7E-23 T 12-10-2018 UA74_08840 23627013512843e4f2be01a8e1e3364a 267 Gene3D G3DSA:3.40.1280.10 1 169 1.2E-63 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_08840 23627013512843e4f2be01a8e1e3364a 267 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 227 4.0E-66 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_08840 23627013512843e4f2be01a8e1e3364a 267 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 233 3.3E-75 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_08840 23627013512843e4f2be01a8e1e3364a 267 Gene3D G3DSA:1.10.1270.20 170 263 8.8E-31 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_08840 23627013512843e4f2be01a8e1e3364a 267 SUPERFAMILY SSF75217 2 239 6.34E-88 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_08840 23627013512843e4f2be01a8e1e3364a 267 PIRSF PIRSF000386 1 257 8.7E-93 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_08840 23627013512843e4f2be01a8e1e3364a 267 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 267 103.308 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UA74_06085 edf518184c2c5000b1f848e327bb601d 248 Gene3D G3DSA:3.40.50.300 9 247 2.6E-71 T 12-10-2018 UA74_06085 edf518184c2c5000b1f848e327bb601d 248 SUPERFAMILY SSF52540 12 229 2.37E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_06085 edf518184c2c5000b1f848e327bb601d 248 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_06085 edf518184c2c5000b1f848e327bb601d 248 Pfam PF00005 ABC transporter 31 177 7.0E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_06085 edf518184c2c5000b1f848e327bb601d 248 SMART SM00382 40 226 9.5E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_11320 f6afd623acb6b752d4bb36a06d851f2b 766 Gene3D G3DSA:3.20.20.210 396 761 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_11320 f6afd623acb6b752d4bb36a06d851f2b 766 PIRSF PIRSF000382 9 766 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_11320 f6afd623acb6b752d4bb36a06d851f2b 766 SUPERFAMILY SSF51726 414 763 7.59E-112 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_11320 f6afd623acb6b752d4bb36a06d851f2b 766 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 436 758 1.5E-145 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_11320 f6afd623acb6b752d4bb36a06d851f2b 766 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 13 321 3.7E-107 T 12-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_11320 f6afd623acb6b752d4bb36a06d851f2b 766 SUPERFAMILY SSF51726 12 394 1.05E-90 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_11320 f6afd623acb6b752d4bb36a06d851f2b 766 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 15 763 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_11320 f6afd623acb6b752d4bb36a06d851f2b 766 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 10 763 33.845 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_11320 f6afd623acb6b752d4bb36a06d851f2b 766 Gene3D G3DSA:3.20.20.210 14 529 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_20245 2db996baaacad36034b71942b9af14d9 516 Gene3D G3DSA:2.60.40.420 122 203 1.2E-24 T 12-10-2018 IPR008972 Cupredoxin UA74_20245 2db996baaacad36034b71942b9af14d9 516 Gene3D G3DSA:2.60.40.420 42 121 7.2E-16 T 12-10-2018 IPR008972 Cupredoxin UA74_20245 2db996baaacad36034b71942b9af14d9 516 SUPERFAMILY SSF49503 210 345 1.31E-22 T 12-10-2018 IPR008972 Cupredoxin UA74_20245 2db996baaacad36034b71942b9af14d9 516 Gene3D G3DSA:2.60.40.420 381 516 8.8E-39 T 12-10-2018 IPR008972 Cupredoxin UA74_20245 2db996baaacad36034b71942b9af14d9 516 Pfam PF07732 Multicopper oxidase 81 206 2.2E-16 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_20245 2db996baaacad36034b71942b9af14d9 516 Gene3D G3DSA:2.60.40.420 204 380 1.1E-49 T 12-10-2018 IPR008972 Cupredoxin UA74_20245 2db996baaacad36034b71942b9af14d9 516 SUPERFAMILY SSF49503 59 207 4.75E-25 T 12-10-2018 IPR008972 Cupredoxin UA74_20245 2db996baaacad36034b71942b9af14d9 516 SUPERFAMILY SSF49503 406 512 6.19E-25 T 12-10-2018 IPR008972 Cupredoxin UA74_20245 2db996baaacad36034b71942b9af14d9 516 Pfam PF07731 Multicopper oxidase 409 514 1.5E-20 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_07090 2f75fc6255cad03781ee4b760c17a71f 191 Pfam PF01923 Cobalamin adenosyltransferase 8 176 1.4E-57 T 12-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_07090 2f75fc6255cad03781ee4b760c17a71f 191 SUPERFAMILY SSF89028 6 183 3.73E-56 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_07090 2f75fc6255cad03781ee4b760c17a71f 191 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 185 2.0E-49 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_07090 2f75fc6255cad03781ee4b760c17a71f 191 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 181 7.2E-52 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_07090 2f75fc6255cad03781ee4b760c17a71f 191 Gene3D G3DSA:1.20.1200.10 29 191 3.7E-59 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 SUPERFAMILY SSF53850 89 287 1.63E-25 T 12-10-2018 UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 Pfam PF03466 LysR substrate binding domain 87 283 2.5E-27 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 SUPERFAMILY SSF46785 1 84 8.08E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 Gene3D G3DSA:1.10.10.10 1 85 9.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.9E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 Gene3D G3DSA:3.40.190.10 161 260 1.8E-25 T 12-10-2018 UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.0E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13415 0d7bd74806038573889f94e1e37a8caa 290 Gene3D G3DSA:3.40.190.10 92 284 1.8E-25 T 12-10-2018 UA74_21310 b72382aa6dfee2e075979ead0e476c1a 323 SUPERFAMILY SSF54637 43 153 1.17E-40 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_21310 b72382aa6dfee2e075979ead0e476c1a 323 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 51 320 3.3E-95 T 12-10-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 UA74_21310 b72382aa6dfee2e075979ead0e476c1a 323 Gene3D G3DSA:3.10.129.90 42 322 6.0E-108 T 12-10-2018 UA74_21310 b72382aa6dfee2e075979ead0e476c1a 323 Pfam PF13622 Thioesterase-like superfamily 70 318 9.5E-61 T 12-10-2018 UA74_21310 b72382aa6dfee2e075979ead0e476c1a 323 SUPERFAMILY SSF54637 155 320 1.33E-52 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_01050 5bcf7e4cb40073b3ed93b211cf694628 311 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 83 8.0E-13 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_01050 5bcf7e4cb40073b3ed93b211cf694628 311 SUPERFAMILY SSF161098 102 291 1.19E-27 T 12-10-2018 IPR035906 MetI-like superfamily UA74_01050 5bcf7e4cb40073b3ed93b211cf694628 311 Gene3D G3DSA:1.10.3720.10 96 310 2.6E-23 T 12-10-2018 IPR035906 MetI-like superfamily UA74_01050 5bcf7e4cb40073b3ed93b211cf694628 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 310 4.0E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_27215 98e843ed3e7b0d6d754def695ee804d6 287 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 49 284 1.7E-96 T 12-10-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 UA74_27215 98e843ed3e7b0d6d754def695ee804d6 287 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 102 143 - T 12-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 UA74_27215 98e843ed3e7b0d6d754def695ee804d6 287 SUPERFAMILY SSF53167 32 284 1.53E-77 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 UA74_27215 98e843ed3e7b0d6d754def695ee804d6 287 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 48 284 1.2E-75 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 UA74_27215 98e843ed3e7b0d6d754def695ee804d6 287 Pfam PF01048 Phosphorylase superfamily 49 284 7.1E-40 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_27215 98e843ed3e7b0d6d754def695ee804d6 287 Gene3D G3DSA:3.40.50.1580 20 286 5.3E-88 T 12-10-2018 UA74_27215 98e843ed3e7b0d6d754def695ee804d6 287 PIRSF PIRSF000477 20 287 5.1E-90 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 UA74_11925 350b6e7f3bf0b98beb757e29ca15a4d1 330 Gene3D G3DSA:3.40.50.970 3 191 9.6E-78 T 12-10-2018 UA74_11925 350b6e7f3bf0b98beb757e29ca15a4d1 330 Pfam PF02780 Transketolase, C-terminal domain 193 314 1.1E-39 T 12-10-2018 IPR033248 Transketolase, C-terminal domain UA74_11925 350b6e7f3bf0b98beb757e29ca15a4d1 330 SUPERFAMILY SSF52518 4 203 2.12E-68 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_11925 350b6e7f3bf0b98beb757e29ca15a4d1 330 SUPERFAMILY SSF52922 190 323 6.94E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_11925 350b6e7f3bf0b98beb757e29ca15a4d1 330 SMART SM00861 4 179 3.1E-61 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_11925 350b6e7f3bf0b98beb757e29ca15a4d1 330 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 9.7E-44 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_11925 350b6e7f3bf0b98beb757e29ca15a4d1 330 Gene3D G3DSA:3.40.50.920 192 325 1.0E-45 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_04280 7e4bd1ac5b966ffaf37b7493c568d779 560 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 267 3.8E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_04280 7e4bd1ac5b966ffaf37b7493c568d779 560 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 369 541 1.7E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_04280 7e4bd1ac5b966ffaf37b7493c568d779 560 SUPERFAMILY SSF161098 291 548 1.44E-40 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04280 7e4bd1ac5b966ffaf37b7493c568d779 560 SUPERFAMILY SSF161098 33 266 1.27E-43 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04280 7e4bd1ac5b966ffaf37b7493c568d779 560 Gene3D G3DSA:1.10.3720.10 295 551 8.8E-43 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04280 7e4bd1ac5b966ffaf37b7493c568d779 560 Gene3D G3DSA:1.10.3720.10 34 277 4.4E-49 T 12-10-2018 IPR035906 MetI-like superfamily UA74_01670 84598983abb0b43dbe77fc9c3b9f8130 162 Pfam PF02559 CarD-like/TRCF domain 3 111 2.0E-18 T 12-10-2018 IPR003711 CarD-like/TRCF domain UA74_01670 84598983abb0b43dbe77fc9c3b9f8130 162 SMART SM01058 2 112 1.1E-32 T 12-10-2018 IPR003711 CarD-like/TRCF domain UA74_01670 84598983abb0b43dbe77fc9c3b9f8130 162 Gene3D G3DSA:1.20.58.1290 61 162 2.6E-39 T 12-10-2018 UA74_01670 84598983abb0b43dbe77fc9c3b9f8130 162 Gene3D G3DSA:2.30.30.840 1 60 4.6E-26 T 12-10-2018 UA74_01670 84598983abb0b43dbe77fc9c3b9f8130 162 SUPERFAMILY SSF141259 3 65 3.53E-14 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily UA74_10360 3897bb102424cdd171fbd662583337a6 603 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_10360 3897bb102424cdd171fbd662583337a6 603 Pfam PF00005 ABC transporter 376 524 1.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_10360 3897bb102424cdd171fbd662583337a6 603 Gene3D G3DSA:3.40.50.300 355 602 5.2E-87 T 12-10-2018 UA74_10360 3897bb102424cdd171fbd662583337a6 603 Pfam PF00664 ABC transporter transmembrane region 37 312 1.1E-58 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_10360 3897bb102424cdd171fbd662583337a6 603 Gene3D G3DSA:1.20.1560.10 4 346 1.8E-100 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_10360 3897bb102424cdd171fbd662583337a6 603 SUPERFAMILY SSF90123 18 346 1.83E-85 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_10360 3897bb102424cdd171fbd662583337a6 603 SUPERFAMILY SSF52540 353 595 3.11E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10360 3897bb102424cdd171fbd662583337a6 603 SMART SM00382 384 576 3.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 Gene3D G3DSA:3.40.50.720 1 261 6.5E-64 T 12-10-2018 UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.3E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.3E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.3E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 SUPERFAMILY SSF51735 7 258 3.42E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 6.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 6.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.7E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_14460 fa5658768e1d304c468265b7c20f2fc0 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 4.8E-45 T 12-10-2018 UA74_24770 be1ace75cd6ed501c3b068b0929cfcc1 594 SUPERFAMILY SSF140453 83 165 2.62E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_24770 be1ace75cd6ed501c3b068b0929cfcc1 594 Gene3D G3DSA:1.10.287.1060 78 169 3.7E-6 T 12-10-2018 UA74_15795 e9f138227390ed601a6b325b3ea9a96a 289 Gene3D G3DSA:3.30.70.141 61 211 1.2E-9 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_15795 e9f138227390ed601a6b325b3ea9a96a 289 SUPERFAMILY SSF54919 61 204 3.4E-13 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_15795 e9f138227390ed601a6b325b3ea9a96a 289 Pfam PF00334 Nucleoside diphosphate kinase 65 200 1.1E-7 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_27615 c5df071dcf60160ba9dc49193bbbd4f4 1350 SUPERFAMILY SSF160424 13 140 3.79E-12 T 12-10-2018 IPR036170 Probable antitoxin YezG superfamily UA74_27615 c5df071dcf60160ba9dc49193bbbd4f4 1350 Pfam PF14021 Tuberculosis necrotizing toxin 1256 1340 3.9E-29 T 12-10-2018 IPR025331 Tuberculosis necrotizing toxin KEGG: 00760+3.2.2.5 UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 Gene3D G3DSA:3.30.70.1450 136 217 1.2E-14 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.6E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 1.6E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 1.6E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.6E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 Pfam PF02080 TrkA-C domain 152 215 2.6E-11 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 Pfam PF02254 TrkA-N domain 3 118 1.4E-24 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 SUPERFAMILY SSF51735 1 145 1.23E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 SUPERFAMILY SSF116726 144 217 9.55E-12 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UA74_08485 ec3370e7345d02f781c6c7e3c5d0fae6 226 Gene3D G3DSA:3.40.50.720 1 131 2.5E-29 T 12-10-2018 UA74_17365 8174a944d29176ccccd4c7e40fbe060b 588 Gene3D G3DSA:2.120.10.30 368 584 4.0E-22 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_17365 8174a944d29176ccccd4c7e40fbe060b 588 Gene3D G3DSA:2.120.10.30 23 174 9.4E-14 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_17365 8174a944d29176ccccd4c7e40fbe060b 588 SUPERFAMILY SSF63829 376 580 2.78E-28 T 12-10-2018 UA74_17365 8174a944d29176ccccd4c7e40fbe060b 588 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 379 581 7.7E-8 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_17365 8174a944d29176ccccd4c7e40fbe060b 588 SUPERFAMILY SSF101898 141 304 2.25E-22 T 12-10-2018 UA74_17365 8174a944d29176ccccd4c7e40fbe060b 588 SUPERFAMILY SSF63825 36 193 1.05E-20 T 12-10-2018 UA74_17365 8174a944d29176ccccd4c7e40fbe060b 588 Gene3D G3DSA:2.120.10.30 191 308 2.9E-9 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_08095 e3bb617357c403de70c0ec76c90d520a 302 Pfam PF00756 Putative esterase 76 256 3.0E-7 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 UA74_08095 e3bb617357c403de70c0ec76c90d520a 302 SUPERFAMILY SSF53474 68 301 4.05E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08095 e3bb617357c403de70c0ec76c90d520a 302 Gene3D G3DSA:3.40.50.1820 69 299 2.6E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22265 495f0047e2f6c25449f698ff465909f4 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 90 4.4E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_22265 495f0047e2f6c25449f698ff465909f4 256 SUPERFAMILY SSF46785 22 94 2.84E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22265 495f0047e2f6c25449f698ff465909f4 256 Gene3D G3DSA:1.20.120.530 112 248 5.5E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_22265 495f0047e2f6c25449f698ff465909f4 256 Pfam PF07729 FCD domain 119 239 2.8E-18 T 12-10-2018 IPR011711 GntR, C-terminal UA74_22265 495f0047e2f6c25449f698ff465909f4 256 SMART SM00895 119 240 9.4E-19 T 12-10-2018 IPR011711 GntR, C-terminal UA74_22265 495f0047e2f6c25449f698ff465909f4 256 Gene3D G3DSA:1.10.10.10 24 91 1.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22265 495f0047e2f6c25449f698ff465909f4 256 SUPERFAMILY SSF48008 117 244 6.02E-19 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_22265 495f0047e2f6c25449f698ff465909f4 256 SMART SM00345 32 90 8.4E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_06200 51a3c26f22268642628607fe1aa8bf2e 99 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 22 93 1.8E-22 T 12-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 UA74_06200 51a3c26f22268642628607fe1aa8bf2e 99 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 2 99 18.042 T 12-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS UA74_06200 51a3c26f22268642628607fe1aa8bf2e 99 Gene3D G3DSA:3.30.1390.10 3 96 1.6E-18 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UA74_06200 51a3c26f22268642628607fe1aa8bf2e 99 SUPERFAMILY SSF54736 22 97 6.28E-25 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UA74_22720 31a3525a909b197f5ef3e1c0184708a6 247 Gene3D G3DSA:3.30.450.40 74 247 3.3E-58 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_22720 31a3525a909b197f5ef3e1c0184708a6 247 Gene3D G3DSA:1.10.10.10 1 73 3.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22720 31a3525a909b197f5ef3e1c0184708a6 247 SUPERFAMILY SSF55781 57 245 8.5E-51 T 12-10-2018 UA74_22720 31a3525a909b197f5ef3e1c0184708a6 247 Pfam PF09339 IclR helix-turn-helix domain 4 52 3.0E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_22720 31a3525a909b197f5ef3e1c0184708a6 247 Pfam PF01614 Bacterial transcriptional regulator 117 241 1.5E-33 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_22720 31a3525a909b197f5ef3e1c0184708a6 247 SUPERFAMILY SSF46785 3 73 1.86E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22720 31a3525a909b197f5ef3e1c0184708a6 247 SMART SM00346 2 89 5.5E-25 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_05685 838988aef848195b7132cd283f9d7428 527 Gene3D G3DSA:1.25.40.10 105 269 3.4E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_05685 838988aef848195b7132cd283f9d7428 527 PRINTS PR00364 Disease resistance protein signature 386 400 6.2E-6 T 12-10-2018 UA74_05685 838988aef848195b7132cd283f9d7428 527 PRINTS PR00364 Disease resistance protein signature 308 323 6.2E-6 T 12-10-2018 UA74_05685 838988aef848195b7132cd283f9d7428 527 PRINTS PR00364 Disease resistance protein signature 474 488 6.2E-6 T 12-10-2018 UA74_05685 838988aef848195b7132cd283f9d7428 527 SUPERFAMILY SSF46894 5 101 5.1E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_05685 838988aef848195b7132cd283f9d7428 527 Pfam PF03704 Bacterial transcriptional activator domain 108 250 1.4E-39 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_05685 838988aef848195b7132cd283f9d7428 527 SMART SM00382 305 445 7.8E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_05685 838988aef848195b7132cd283f9d7428 527 SMART SM00862 19 101 3.8E-11 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_05685 838988aef848195b7132cd283f9d7428 527 Gene3D G3DSA:3.40.50.300 270 431 3.1E-23 T 12-10-2018 UA74_05685 838988aef848195b7132cd283f9d7428 527 SUPERFAMILY SSF48452 104 266 3.79E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_05685 838988aef848195b7132cd283f9d7428 527 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 101 7.6E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_05685 838988aef848195b7132cd283f9d7428 527 SUPERFAMILY SSF52540 275 505 1.85E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_05685 838988aef848195b7132cd283f9d7428 527 Gene3D G3DSA:1.10.10.10 2 103 4.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_05685 838988aef848195b7132cd283f9d7428 527 SMART SM01043 108 250 5.6E-44 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_03650 eaaef550779c2ec321a1644bc472c215 317 PRINTS PR00075 Fatty acid desaturase family 1 signature 259 273 5.6E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_03650 eaaef550779c2ec321a1644bc472c215 317 PRINTS PR00075 Fatty acid desaturase family 1 signature 56 78 5.6E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_03650 eaaef550779c2ec321a1644bc472c215 317 PRINTS PR00075 Fatty acid desaturase family 1 signature 216 237 5.6E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_03650 eaaef550779c2ec321a1644bc472c215 317 PRINTS PR00075 Fatty acid desaturase family 1 signature 79 99 5.6E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_03650 eaaef550779c2ec321a1644bc472c215 317 Pfam PF00487 Fatty acid desaturase 57 275 4.2E-20 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 SMART SM00862 692 771 1.6E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 SMART SM01043 778 917 2.5E-17 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 Pfam PF01476 LysM domain 180 229 1.5E-6 T 12-10-2018 IPR018392 LysM domain UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 SUPERFAMILY SSF46894 673 758 7.94E-9 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 Pfam PF03704 Bacterial transcriptional activator domain 778 916 1.0E-9 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 SUPERFAMILY SSF48452 798 929 2.16E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 Gene3D G3DSA:3.10.350.10 178 227 4.3E-9 T 12-10-2018 IPR036779 LysM domain superfamily UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 Gene3D G3DSA:1.25.40.10 777 946 2.8E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 Gene3D G3DSA:1.10.10.10 663 773 4.6E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16145 c80e514530f0a751a4b0264df66d6ea8 952 Pfam PF00486 Transcriptional regulatory protein, C terminal 698 761 1.4E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_29085 86b822131340117b879834acb7f045ef 220 SUPERFAMILY SSF109755 2 213 1.67E-55 T 12-10-2018 UA74_29085 86b822131340117b879834acb7f045ef 220 Pfam PF01895 PhoU domain 16 102 1.7E-15 T 12-10-2018 IPR026022 PhoU domain UA74_29085 86b822131340117b879834acb7f045ef 220 Pfam PF01895 PhoU domain 123 204 3.9E-11 T 12-10-2018 IPR026022 PhoU domain UA74_29085 86b822131340117b879834acb7f045ef 220 Gene3D G3DSA:1.20.58.220 1 216 5.3E-59 T 12-10-2018 IPR038078 PhoU-like domain superfamily UA74_29085 86b822131340117b879834acb7f045ef 220 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 4.6E-53 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 UA74_29085 86b822131340117b879834acb7f045ef 220 PIRSF PIRSF003107 1 217 3.2E-53 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 4.1E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 4.1E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 4.1E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 SUPERFAMILY SSF53474 4 273 8.45E-72 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 94 107 2.3E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 249 271 2.3E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 108 121 2.3E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 28 46 2.3E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 PRINTS PR00412 Epoxide hydrolase signature 48 63 2.3E-25 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 Gene3D G3DSA:3.40.50.1820 1 271 1.1E-79 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05745 3f4e322e15f316603b3613fdbe2c45ab 287 Pfam PF00561 alpha/beta hydrolase fold 23 137 3.5E-28 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_01485 9272ad292decd37b7e7df9e32764bd8f 736 Gene3D G3DSA:3.40.50.300 447 577 7.0E-7 T 12-10-2018 UA74_01485 9272ad292decd37b7e7df9e32764bd8f 736 Gene3D G3DSA:3.40.50.300 166 310 3.5E-10 T 12-10-2018 UA74_01485 9272ad292decd37b7e7df9e32764bd8f 736 SUPERFAMILY SSF52540 169 712 9.76E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01485 9272ad292decd37b7e7df9e32764bd8f 736 Gene3D G3DSA:3.40.50.300 661 725 1.2E-9 T 12-10-2018 UA74_01485 9272ad292decd37b7e7df9e32764bd8f 736 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 191 234 9.4E-5 T 12-10-2018 IPR018647 Domain of unknown function DUF2075 UA74_19605 c3eb2a5a4a106e856f8f7d56c2fc0794 227 Gene3D G3DSA:3.40.50.300 1 224 4.5E-56 T 12-10-2018 UA74_19605 c3eb2a5a4a106e856f8f7d56c2fc0794 227 SMART SM00382 23 201 3.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_19605 c3eb2a5a4a106e856f8f7d56c2fc0794 227 SUPERFAMILY SSF52540 2 215 2.38E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19605 c3eb2a5a4a106e856f8f7d56c2fc0794 227 Pfam PF00005 ABC transporter 16 152 1.8E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_19605 c3eb2a5a4a106e856f8f7d56c2fc0794 227 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_03670 fc5b518a97d84009dac2ba362cf0c0fd 316 Gene3D G3DSA:1.10.287.70 108 162 1.4E-19 T 12-10-2018 UA74_03670 fc5b518a97d84009dac2ba362cf0c0fd 316 Gene3D G3DSA:1.20.5.110 164 205 1.2E-13 T 12-10-2018 UA74_03670 fc5b518a97d84009dac2ba362cf0c0fd 316 SUPERFAMILY SSF81324 17 198 5.42E-34 T 12-10-2018 UA74_03670 fc5b518a97d84009dac2ba362cf0c0fd 316 PRINTS PR01333 Two pore domain K+ channel signature 288 297 2.1E-6 T 12-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 UA74_03670 fc5b518a97d84009dac2ba362cf0c0fd 316 PRINTS PR01333 Two pore domain K+ channel signature 155 183 2.1E-6 T 12-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 UA74_03670 fc5b518a97d84009dac2ba362cf0c0fd 316 Pfam PF07885 Ion channel 122 199 1.9E-14 T 12-10-2018 IPR013099 Potassium channel domain UA74_08005 90b23c17c6f7825537ab1ffc49774ab8 254 SUPERFAMILY SSF161098 3 246 7.41E-51 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08005 90b23c17c6f7825537ab1ffc49774ab8 254 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 43 246 6.1E-70 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 UA74_08005 90b23c17c6f7825537ab1ffc49774ab8 254 Gene3D G3DSA:1.10.3720.10 1 250 5.2E-67 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08005 90b23c17c6f7825537ab1ffc49774ab8 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 60 244 1.4E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_08005 90b23c17c6f7825537ab1ffc49774ab8 254 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 21 243 2.0E-71 T 12-10-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0016020|GO:0055085 UA74_13135 cf5b03151e10bf260e5798dd178270d6 586 ProSitePatterns PS01303 BCCT family of transporters signature. 337 346 - T 12-10-2018 IPR018093 BCCT transporter, conserved site UA74_13135 cf5b03151e10bf260e5798dd178270d6 586 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 30 522 2.0E-188 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 UA74_13135 cf5b03151e10bf260e5798dd178270d6 586 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 68 523 7.4E-162 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 UA74_24360 435c1247e7a826a716c235b5a1b29b51 441 SMART SM00093 80 440 1.4E-67 T 12-10-2018 IPR023796 Serpin domain UA74_24360 435c1247e7a826a716c235b5a1b29b51 441 ProSitePatterns PS00284 Serpins signature. 413 423 - T 12-10-2018 IPR023795 Serpin, conserved site UA74_24360 435c1247e7a826a716c235b5a1b29b51 441 Pfam PF00079 Serpin (serine protease inhibitor) 77 440 5.0E-79 T 12-10-2018 IPR023796 Serpin domain UA74_24360 435c1247e7a826a716c235b5a1b29b51 441 Gene3D G3DSA:3.30.497.10 78 385 4.1E-86 T 12-10-2018 UA74_24360 435c1247e7a826a716c235b5a1b29b51 441 SUPERFAMILY SSF56574 74 440 3.93E-86 T 12-10-2018 IPR036186 Serpin superfamily UA74_24360 435c1247e7a826a716c235b5a1b29b51 441 Gene3D G3DSA:2.30.39.10 243 440 4.1E-86 T 12-10-2018 UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 Gene3D G3DSA:3.50.50.100 1 369 2.1E-78 T 12-10-2018 UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 279 2.6E-42 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 SUPERFAMILY SSF51905 3 315 1.01E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.6E-17 T 12-10-2018 UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 6.6E-17 T 12-10-2018 UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 6.6E-17 T 12-10-2018 UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 279 7.3E-12 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 7.3E-12 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 139 163 7.3E-12 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_09915 03dba555b2847a75d97d2edeefc633cc 388 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 7.3E-12 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_03345 f33cdff20b3f7f5c23af92c501cbec92 190 Pfam PF12867 DinB superfamily 13 174 5.4E-18 T 12-10-2018 IPR024775 DinB-like domain UA74_03345 f33cdff20b3f7f5c23af92c501cbec92 190 SUPERFAMILY SSF109854 10 182 1.67E-15 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_13675 5340b76458c127e63f6bfaeb437c3750 146 Gene3D G3DSA:3.30.450.30 9 134 5.4E-40 T 12-10-2018 UA74_13675 5340b76458c127e63f6bfaeb437c3750 146 SUPERFAMILY SSF103196 6 130 9.94E-29 T 12-10-2018 UA74_13675 5340b76458c127e63f6bfaeb437c3750 146 Pfam PF03259 Roadblock/LC7 domain 13 103 2.6E-20 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain UA74_13675 5340b76458c127e63f6bfaeb437c3750 146 SMART SM00960 13 103 1.1E-29 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain UA74_06585 d7f3e2708fd83d71fa65bb79a16672b6 105 SUPERFAMILY SSF50022 2 98 1.44E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_06585 d7f3e2708fd83d71fa65bb79a16672b6 105 Pfam PF00355 Rieske [2Fe-2S] domain 2 86 9.6E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_06585 d7f3e2708fd83d71fa65bb79a16672b6 105 Gene3D G3DSA:2.102.10.10 1 103 3.2E-34 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_29715 680587e5d665e10e1cb9d03371c48585 681 SUPERFAMILY SSF50494 221 390 8.23E-23 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_29715 680587e5d665e10e1cb9d03371c48585 681 Gene3D G3DSA:2.60.40.10 518 602 7.8E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_29715 680587e5d665e10e1cb9d03371c48585 681 Gene3D G3DSA:2.60.40.10 427 506 6.3E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_29715 680587e5d665e10e1cb9d03371c48585 681 Gene3D G3DSA:2.40.10.10 296 393 3.3E-34 T 12-10-2018 UA74_29715 680587e5d665e10e1cb9d03371c48585 681 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 362 373 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site UA74_29715 680587e5d665e10e1cb9d03371c48585 681 Gene3D G3DSA:3.30.300.50 46 127 2.0E-7 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_29715 680587e5d665e10e1cb9d03371c48585 681 Pfam PF00089 Trypsin 239 391 1.8E-6 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_29715 680587e5d665e10e1cb9d03371c48585 681 Gene3D G3DSA:2.40.10.10 221 295 3.3E-34 T 12-10-2018 UA74_29715 680587e5d665e10e1cb9d03371c48585 681 Pfam PF02983 Alpha-lytic protease prodomain 131 187 6.5E-5 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 SUPERFAMILY SSF48173 189 459 2.49E-98 T 12-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Gene3D G3DSA:1.10.579.10 282 462 4.9E-73 T 12-10-2018 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Gene3D G3DSA:1.25.40.80 127 277 5.6E-67 T 12-10-2018 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Pfam PF03441 FAD binding domain of DNA photolyase 264 457 1.3E-78 T 12-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 PRINTS PR00147 DNA photolyase signature 375 389 6.4E-23 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 PRINTS PR00147 DNA photolyase signature 316 332 6.4E-23 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 PRINTS PR00147 DNA photolyase signature 138 154 6.4E-23 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 PRINTS PR00147 DNA photolyase signature 336 354 6.4E-23 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Gene3D G3DSA:3.40.50.620 8 200 5.6E-67 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 SUPERFAMILY SSF52425 5 172 1.31E-42 T 12-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 UA74_28225 d65956bfb1df2f0e8bd8b6f9d715c28e 463 Pfam PF00875 DNA photolyase 7 158 9.8E-41 T 12-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 UA74_20520 bfff87368be8c6310abb8ea2197f3ea0 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 420 3.3E-106 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 UA74_20520 bfff87368be8c6310abb8ea2197f3ea0 425 PIRSF PIRSF006066 1 425 1.2E-122 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 UA74_20520 bfff87368be8c6310abb8ea2197f3ea0 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 414 1.4E-99 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit UA74_21105 99ee7a876bb26082f2030233186ec3df 265 SUPERFAMILY SSF46785 16 87 1.36E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_21105 99ee7a876bb26082f2030233186ec3df 265 Pfam PF09339 IclR helix-turn-helix domain 16 65 3.1E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_21105 99ee7a876bb26082f2030233186ec3df 265 Gene3D G3DSA:3.30.450.40 86 262 4.9E-56 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_21105 99ee7a876bb26082f2030233186ec3df 265 Pfam PF01614 Bacterial transcriptional regulator 131 252 1.2E-28 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_21105 99ee7a876bb26082f2030233186ec3df 265 SMART SM00346 14 103 2.1E-20 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_21105 99ee7a876bb26082f2030233186ec3df 265 Gene3D G3DSA:1.10.10.10 2 81 4.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21105 99ee7a876bb26082f2030233186ec3df 265 SUPERFAMILY SSF55781 85 258 3.73E-49 T 12-10-2018 UA74_07455 827a7018e91d4797066ff9e9c22e7f79 393 SUPERFAMILY SSF55874 274 388 5.02E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_07455 827a7018e91d4797066ff9e9c22e7f79 393 Pfam PF07730 Histidine kinase 193 257 1.1E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_07455 827a7018e91d4797066ff9e9c22e7f79 393 Gene3D G3DSA:3.30.565.10 265 389 6.8E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_28325 13ae129b432eff7a3e12b66e25d14427 524 Pfam PF00860 Permease family 65 477 5.8E-28 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 UA74_22880 7107c760175876abecd19918335669fc 523 SUPERFAMILY SSF103473 8 498 3.14E-59 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_22880 7107c760175876abecd19918335669fc 523 Gene3D G3DSA:1.20.1250.20 269 506 1.2E-16 T 12-10-2018 UA74_22880 7107c760175876abecd19918335669fc 523 Gene3D G3DSA:1.20.1720.10 19 231 1.1E-41 T 12-10-2018 UA74_22880 7107c760175876abecd19918335669fc 523 Pfam PF07690 Major Facilitator Superfamily 26 413 2.8E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_06145 05672ec7f70c6dd2191452397ddced01 147 SUPERFAMILY SSF53335 14 146 7.93E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_06145 05672ec7f70c6dd2191452397ddced01 147 Pfam PF04672 S-adenosyl methyltransferase 10 144 2.7E-53 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_06145 05672ec7f70c6dd2191452397ddced01 147 Gene3D G3DSA:3.40.50.150 5 147 1.2E-58 T 12-10-2018 UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:2.60.120.380 459 603 2.9E-195 T 12-10-2018 UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 SUPERFAMILY SSF50405 486 565 3.07E-7 T 12-10-2018 IPR008999 Actin-crosslinking UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 Pfam PF14310 Fibronectin type III-like domain 781 851 9.8E-20 T 12-10-2018 IPR026891 Fibronectin type III-like domain UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 SUPERFAMILY SSF52279 382 747 3.27E-49 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:3.40.50.1700 375 711 2.9E-195 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:2.60.40.10 747 863 6.5E-29 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 SUPERFAMILY SSF51445 17 381 8.32E-71 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 PRINTS PR00133 Glycosyl hydrolase family 3 signature 169 185 1.1E-7 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 PRINTS PR00133 Glycosyl hydrolase family 3 signature 80 99 1.1E-7 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 SUPERFAMILY SSF49785 872 973 6.16E-6 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 SMART SM01217 781 851 2.4E-25 T 12-10-2018 IPR026891 Fibronectin type III-like domain UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 64 320 2.5E-37 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:2.60.120.260 871 989 1.2E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 382 744 3.9E-61 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_07320 bca070dde340ec8e99dae303bf89b2b5 1048 Gene3D G3DSA:3.20.20.300 33 746 2.9E-195 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 UA74_30080 f9fbc482a09a929704a7d0d0c991eeb2 419 Pfam PF07690 Major Facilitator Superfamily 20 323 4.0E-35 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_30080 f9fbc482a09a929704a7d0d0c991eeb2 419 Gene3D G3DSA:1.20.1250.20 207 392 6.9E-12 T 12-10-2018 UA74_30080 f9fbc482a09a929704a7d0d0c991eeb2 419 SUPERFAMILY SSF103473 11 391 9.02E-52 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_30080 f9fbc482a09a929704a7d0d0c991eeb2 419 Gene3D G3DSA:1.20.1250.20 12 196 4.2E-24 T 12-10-2018 UA74_00345 a557f1bcb87d5869e071a9fcb178a306 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 56 8.6E-10 T 12-10-2018 UA74_00345 a557f1bcb87d5869e071a9fcb178a306 83 SUPERFAMILY SSF143120 1 81 4.58E-24 T 12-10-2018 IPR036165 YefM-like superfamily UA74_00345 a557f1bcb87d5869e071a9fcb178a306 83 Gene3D G3DSA:3.40.1620.10 1 40 4.2E-11 T 12-10-2018 UA74_00345 a557f1bcb87d5869e071a9fcb178a306 83 Gene3D G3DSA:1.10.1220.170 41 83 1.5E-17 T 12-10-2018 UA74_00345 a557f1bcb87d5869e071a9fcb178a306 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 73 3.1E-21 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_26425 2be2ce3e016100076e526a218a5bab23 496 SUPERFAMILY SSF55785 180 291 1.71E-7 T 12-10-2018 IPR035965 PAS domain superfamily UA74_26425 2be2ce3e016100076e526a218a5bab23 496 Gene3D G3DSA:3.30.450.280 1 136 2.7E-43 T 12-10-2018 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily UA74_26425 2be2ce3e016100076e526a218a5bab23 496 Gene3D G3DSA:3.30.565.10 356 496 1.1E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_26425 2be2ce3e016100076e526a218a5bab23 496 Pfam PF12282 Signal transduction histidine kinase 4 151 3.7E-54 T 12-10-2018 IPR022066 Signal transduction histidine kinase, N-terminal UA74_26425 2be2ce3e016100076e526a218a5bab23 496 Pfam PF13581 Histidine kinase-like ATPase domain 389 468 1.3E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_26425 2be2ce3e016100076e526a218a5bab23 496 Pfam PF07568 Histidine kinase 300 369 1.8E-22 T 12-10-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain UA74_26425 2be2ce3e016100076e526a218a5bab23 496 SMART SM00387 394 494 2.0E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_26425 2be2ce3e016100076e526a218a5bab23 496 SUPERFAMILY SSF55874 355 493 1.57E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_26425 2be2ce3e016100076e526a218a5bab23 496 Pfam PF08448 PAS fold 178 286 8.0E-9 T 12-10-2018 IPR013656 PAS fold-4 UA74_26425 2be2ce3e016100076e526a218a5bab23 496 Gene3D G3DSA:3.30.450.20 137 286 6.0E-42 T 12-10-2018 UA74_16640 3fd58422ccd57c8fad4fd62d64dec8a8 244 Pfam PF12730 ABC-2 family transporter protein 22 157 2.7E-6 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UA74_02565 9ff2f57cf56124b977bc85efd1e1deaf 183 Gene3D G3DSA:3.40.50.12280 2 168 4.1E-74 T 12-10-2018 UA74_02565 9ff2f57cf56124b977bc85efd1e1deaf 183 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 151 2.2E-70 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02565 9ff2f57cf56124b977bc85efd1e1deaf 183 SUPERFAMILY SSF56770 9 153 1.7E-66 T 12-10-2018 UA74_02565 9ff2f57cf56124b977bc85efd1e1deaf 183 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 43.144 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02565 9ff2f57cf56124b977bc85efd1e1deaf 183 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 4.1E-25 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02565 9ff2f57cf56124b977bc85efd1e1deaf 183 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_28350 8ea038abb289f6fca5aa34a578fb32a1 759 Gene3D G3DSA:1.20.1250.20 325 704 2.9E-12 T 12-10-2018 UA74_28350 8ea038abb289f6fca5aa34a578fb32a1 759 Pfam PF07690 Major Facilitator Superfamily 329 673 8.1E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_28350 8ea038abb289f6fca5aa34a578fb32a1 759 SUPERFAMILY SSF103473 324 705 4.71E-26 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_23125 b595d4fc024269721ca9839a4784d792 187 SUPERFAMILY SSF55811 12 177 6.63E-45 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_23125 b595d4fc024269721ca9839a4784d792 187 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 12 185 34.208 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_23125 b595d4fc024269721ca9839a4784d792 187 PIRSF PIRSF018427 1 184 9.9E-51 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_23125 b595d4fc024269721ca9839a4784d792 187 Gene3D G3DSA:3.90.79.10 10 181 7.2E-50 T 12-10-2018 UA74_23125 b595d4fc024269721ca9839a4784d792 187 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 14 173 1.0E-43 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_23125 b595d4fc024269721ca9839a4784d792 187 Pfam PF00293 NUDIX domain 39 155 4.7E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_25885 9150701b64345dd78c49ccdbc82c96a5 257 SUPERFAMILY SSF56529 52 255 1.44E-79 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 UA74_25885 9150701b64345dd78c49ccdbc82c96a5 257 Pfam PF10370 Domain of unknown function (DUF2437) 2 55 1.1E-13 T 12-10-2018 IPR018833 Domain of unknown function DUF2437 UA74_25885 9150701b64345dd78c49ccdbc82c96a5 257 Gene3D G3DSA:3.90.850.10 56 257 4.2E-84 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 UA74_25885 9150701b64345dd78c49ccdbc82c96a5 257 Gene3D G3DSA:2.30.30.370 1 55 6.0E-28 T 12-10-2018 UA74_25885 9150701b64345dd78c49ccdbc82c96a5 257 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 60 255 2.8E-67 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 UA74_16700 dafe9758cbc7eaba69d96cfcab451bc2 354 Gene3D G3DSA:1.10.3470.10 15 353 1.8E-98 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_16700 dafe9758cbc7eaba69d96cfcab451bc2 354 Pfam PF01032 FecCD transport family 29 347 5.2E-90 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_16700 dafe9758cbc7eaba69d96cfcab451bc2 354 SUPERFAMILY SSF81345 14 348 2.09E-79 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 Pfam PF00009 Elongation factor Tu GTP binding domain 111 271 2.9E-33 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 Gene3D G3DSA:2.40.30.10 283 401 2.1E-38 T 12-10-2018 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 19 610 6.9E-222 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 109 268 5.3E-31 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 Pfam PF11987 Translation-initiation factor 2 398 501 3.5E-31 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 2 610 15.794 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 PRINTS PR00315 GTP-binding elongation factor signature 110 123 4.5E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 PRINTS PR00315 GTP-binding elongation factor signature 214 223 4.5E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 PRINTS PR00315 GTP-binding elongation factor signature 178 189 4.5E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 PRINTS PR00315 GTP-binding elongation factor signature 162 172 4.5E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 SUPERFAMILY SSF50447 513 610 1.31E-27 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 ProSitePatterns PS01176 Initiation factor 2 signature. 563 585 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 SUPERFAMILY SSF52156 391 518 7.32E-34 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 SUPERFAMILY SSF50447 284 367 1.15E-22 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 Gene3D G3DSA:3.40.50.10050 405 512 1.3E-31 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 Gene3D G3DSA:3.40.50.300 104 282 7.2E-67 T 12-10-2018 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 27 72 7.0E-6 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 Gene3D G3DSA:2.40.30.10 513 611 9.5E-29 T 12-10-2018 UA74_09245 3bfaf7d749175b9c7c85e1a2bdc24f3e 611 SUPERFAMILY SSF52540 106 273 2.85E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22375 06e6ac4c67c0e1e5409c07294ba13504 364 Pfam PF06224 Winged helix DNA-binding domain 31 345 1.3E-69 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 UA74_22825 9b651d99699dbe8a253af938f85e2848 510 Gene3D G3DSA:3.30.70.2450 188 270 4.2E-98 T 12-10-2018 UA74_22825 9b651d99699dbe8a253af938f85e2848 510 SUPERFAMILY SSF51905 7 377 1.3E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_22825 9b651d99699dbe8a253af938f85e2848 510 Gene3D G3DSA:3.50.50.60 9 347 4.2E-98 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_22825 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 4.5E-43 T 12-10-2018 UA74_22825 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 4.5E-43 T 12-10-2018 UA74_22825 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 314 332 4.5E-43 T 12-10-2018 UA74_22825 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 348 4.5E-43 T 12-10-2018 UA74_22825 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 4.5E-43 T 12-10-2018 UA74_22825 9b651d99699dbe8a253af938f85e2848 510 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 4.5E-43 T 12-10-2018 UA74_22825 9b651d99699dbe8a253af938f85e2848 510 Pfam PF01494 FAD binding domain 8 346 5.1E-69 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 SUPERFAMILY SSF81464 17 115 8.99E-22 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 SUPERFAMILY SSF49503 122 258 1.75E-32 T 12-10-2018 IPR008972 Cupredoxin UA74_24945 da59bd7e790b39e452b3693c0d117698 305 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 43 251 6.4E-44 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 Gene3D G3DSA:1.10.287.90 35 115 7.3E-15 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 224 241 8.1E-8 T 12-10-2018 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 123 142 8.1E-8 T 12-10-2018 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 206 223 8.1E-8 T 12-10-2018 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 PRINTS PR01166 Cytochrome c oxidase subunit II signature 88 100 8.1E-8 T 12-10-2018 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 164 241 2.4E-14 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 34 107 9.0E-5 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_24945 da59bd7e790b39e452b3693c0d117698 305 Gene3D G3DSA:2.60.40.420 116 285 1.5E-34 T 12-10-2018 IPR008972 Cupredoxin UA74_24945 da59bd7e790b39e452b3693c0d117698 305 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 182 235 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_05235 9b4cfeef1c533f8c7f4881b972abd34f 312 SMART SM00382 28 206 8.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_05235 9b4cfeef1c533f8c7f4881b972abd34f 312 SUPERFAMILY SSF52540 3 221 1.51E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_05235 9b4cfeef1c533f8c7f4881b972abd34f 312 Pfam PF00005 ABC transporter 20 157 3.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_05235 9b4cfeef1c533f8c7f4881b972abd34f 312 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_05235 9b4cfeef1c533f8c7f4881b972abd34f 312 Gene3D G3DSA:3.40.50.300 1 234 8.0E-66 T 12-10-2018 UA74_13380 730349610f6e1ea40b688dc5b0b57845 186 Gene3D G3DSA:2.60.120.10 75 171 3.6E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_13380 730349610f6e1ea40b688dc5b0b57845 186 Gene3D G3DSA:1.10.260.40 4 74 1.9E-17 T 12-10-2018 UA74_13380 730349610f6e1ea40b688dc5b0b57845 186 Pfam PF01381 Helix-turn-helix 9 63 1.4E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_13380 730349610f6e1ea40b688dc5b0b57845 186 Pfam PF07883 Cupin domain 112 170 4.6E-10 T 12-10-2018 IPR013096 Cupin 2, conserved barrel UA74_13380 730349610f6e1ea40b688dc5b0b57845 186 SUPERFAMILY SSF51182 59 170 4.46E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_13380 730349610f6e1ea40b688dc5b0b57845 186 SMART SM00530 8 63 2.0E-18 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_13380 730349610f6e1ea40b688dc5b0b57845 186 SUPERFAMILY SSF47413 5 68 1.9E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 SUPERFAMILY SSF47323 400 581 2.43E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 SUPERFAMILY SSF52374 6 399 7.11E-92 T 12-10-2018 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 Gene3D G3DSA:3.40.50.620 6 394 2.0E-143 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 592 38.021 T 12-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 253 264 3.3E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 3.3E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 399 410 3.3E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.3E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 3.3E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 PRINTS PR01041 Methionyl-tRNA synthetase signature 293 308 3.3E-25 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 Gene3D G3DSA:2.20.28.20 140 174 2.0E-143 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 543 3.7E-147 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 Gene3D G3DSA:1.10.730.10 395 588 1.6E-36 T 12-10-2018 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 Pfam PF09334 tRNA synthetases class I (M) 6 411 8.4E-144 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_03430 7d6739cb0fd76ad0e395e96802df63a7 597 SUPERFAMILY SSF57770 140 173 4.58E-11 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_28065 0992cfb16a2022cf5317704b0b9fd911 1329 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 753 1322 8.2E-233 T 12-10-2018 IPR023837 EccCb-like, Actinobacteria UA74_28065 0992cfb16a2022cf5317704b0b9fd911 1329 Gene3D G3DSA:3.40.50.300 205 375 1.0E-10 T 12-10-2018 UA74_28065 0992cfb16a2022cf5317704b0b9fd911 1329 Gene3D G3DSA:3.40.50.300 775 1082 3.5E-90 T 12-10-2018 UA74_28065 0992cfb16a2022cf5317704b0b9fd911 1329 SUPERFAMILY SSF52540 440 660 5.62E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28065 0992cfb16a2022cf5317704b0b9fd911 1329 Pfam PF01580 FtsK/SpoIIIE family 813 1039 4.4E-50 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_28065 0992cfb16a2022cf5317704b0b9fd911 1329 Pfam PF01580 FtsK/SpoIIIE family 447 576 1.6E-22 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_28065 0992cfb16a2022cf5317704b0b9fd911 1329 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 697 1.5E-278 T 12-10-2018 IPR023836 EccCa-like, Actinobacteria UA74_28065 0992cfb16a2022cf5317704b0b9fd911 1329 SUPERFAMILY SSF52540 771 1021 2.84E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28065 0992cfb16a2022cf5317704b0b9fd911 1329 Gene3D G3DSA:3.40.50.300 1091 1326 8.6E-51 T 12-10-2018 UA74_18825 b53b0eb57f68d9e1ffcb71f0fac47748 118 SUPERFAMILY SSF54593 1 116 9.93E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_18825 b53b0eb57f68d9e1ffcb71f0fac47748 118 Gene3D G3DSA:3.10.180.10 2 118 2.8E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_18825 b53b0eb57f68d9e1ffcb71f0fac47748 118 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 111 2.7E-4 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_01795 8b56bf6139bbb0b77fa669b780e96f88 379 SMART SM00354 23 94 6.6E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_01795 8b56bf6139bbb0b77fa669b780e96f88 379 Pfam PF13377 Periplasmic binding protein-like domain 192 365 6.5E-27 T 12-10-2018 UA74_01795 8b56bf6139bbb0b77fa669b780e96f88 379 Gene3D G3DSA:3.40.50.2300 183 328 9.3E-58 T 12-10-2018 UA74_01795 8b56bf6139bbb0b77fa669b780e96f88 379 SUPERFAMILY SSF53822 96 360 4.91E-46 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_01795 8b56bf6139bbb0b77fa669b780e96f88 379 Gene3D G3DSA:1.10.260.40 15 77 8.2E-17 T 12-10-2018 UA74_01795 8b56bf6139bbb0b77fa669b780e96f88 379 Gene3D G3DSA:3.40.50.2300 78 343 9.3E-58 T 12-10-2018 UA74_01795 8b56bf6139bbb0b77fa669b780e96f88 379 SUPERFAMILY SSF47413 23 81 4.22E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_01795 8b56bf6139bbb0b77fa669b780e96f88 379 Pfam PF00356 Bacterial regulatory proteins, lacI family 26 67 4.7E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_17080 b5f640b324a29dd949ce9630ca483883 227 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_17080 b5f640b324a29dd949ce9630ca483883 227 Gene3D G3DSA:1.10.10.10 140 215 5.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17080 b5f640b324a29dd949ce9630ca483883 227 SUPERFAMILY SSF46785 147 218 2.86E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_17080 b5f640b324a29dd949ce9630ca483883 227 SUPERFAMILY SSF55811 5 142 1.9E-27 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_17080 b5f640b324a29dd949ce9630ca483883 227 Gene3D G3DSA:3.90.79.10 1 138 8.7E-39 T 12-10-2018 UA74_17080 b5f640b324a29dd949ce9630ca483883 227 Pfam PF00293 NUDIX domain 6 132 1.0E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 623 698 1.4E-17 T 12-10-2018 IPR011709 Domain of unknown function DUF1605 UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Pfam PF11898 Domain of unknown function (DUF3418) 713 1297 9.4E-232 T 12-10-2018 IPR024590 RNA helicase HrpA, C-terminal UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SUPERFAMILY SSF52540 77 602 5.11E-112 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 15 1296 0.0 T 12-10-2018 IPR010222 RNA helicase HrpA GO:0004004 UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SMART SM00487 76 262 7.4E-25 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SMART SM00847 465 560 1.6E-37 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SMART SM00382 95 385 8.6E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Gene3D G3DSA:3.40.50.300 45 255 9.5E-76 T 12-10-2018 UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Pfam PF04408 Helicase associated domain (HA2) 467 556 1.6E-18 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 SMART SM00490 305 405 8.0E-13 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Gene3D G3DSA:1.20.120.1080 450 558 6.4E-20 T 12-10-2018 UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Pfam PF00271 Helicase conserved C-terminal domain 287 404 3.1E-10 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_11955 cf6a13e30859c5b4bdc73eee3141b4d3 1300 Gene3D G3DSA:3.40.50.300 256 421 9.1E-57 T 12-10-2018 UA74_23240 c342e3f79730d1b28bc4aa7177daf12b 229 Pfam PF03992 Antibiotic biosynthesis monooxygenase 141 195 1.3E-4 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_23240 c342e3f79730d1b28bc4aa7177daf12b 229 SUPERFAMILY SSF54909 130 195 3.17E-9 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_23240 c342e3f79730d1b28bc4aa7177daf12b 229 SUPERFAMILY SSF54909 51 84 2.19E-5 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_23240 c342e3f79730d1b28bc4aa7177daf12b 229 Gene3D G3DSA:3.30.70.100 11 115 6.2E-27 T 12-10-2018 UA74_23240 c342e3f79730d1b28bc4aa7177daf12b 229 Gene3D G3DSA:3.30.70.100 121 225 9.7E-17 T 12-10-2018 UA74_16710 cb6a36f06f9ab97bbbc79ade6873bcea 331 Gene3D G3DSA:3.40.50.1980 158 329 2.0E-31 T 12-10-2018 UA74_16710 cb6a36f06f9ab97bbbc79ade6873bcea 331 SUPERFAMILY SSF53807 55 329 1.3E-44 T 12-10-2018 UA74_16710 cb6a36f06f9ab97bbbc79ade6873bcea 331 Pfam PF01497 Periplasmic binding protein 64 301 2.6E-28 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_16710 cb6a36f06f9ab97bbbc79ade6873bcea 331 Gene3D G3DSA:3.40.50.1980 39 157 2.1E-14 T 12-10-2018 UA74_00950 79d4c8a8571e0dc1ea602531c22b1c52 317 SUPERFAMILY SSF51430 6 313 2.1E-83 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_00950 79d4c8a8571e0dc1ea602531c22b1c52 317 Gene3D G3DSA:3.20.20.100 2 317 1.3E-99 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_00950 79d4c8a8571e0dc1ea602531c22b1c52 317 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_00950 79d4c8a8571e0dc1ea602531c22b1c52 317 Pfam PF00248 Aldo/keto reductase family 7 304 1.7E-66 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_00950 79d4c8a8571e0dc1ea602531c22b1c52 317 PRINTS PR00069 Aldo-keto reductase signature 31 55 4.5E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_00950 79d4c8a8571e0dc1ea602531c22b1c52 317 PRINTS PR00069 Aldo-keto reductase signature 126 143 4.5E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_00950 79d4c8a8571e0dc1ea602531c22b1c52 317 PRINTS PR00069 Aldo-keto reductase signature 95 113 4.5E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_03635 0842b6ff3bfb5aab07caa84992a5a1c0 507 SUPERFAMILY SSF53448 20 276 5.63E-60 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_03635 0842b6ff3bfb5aab07caa84992a5a1c0 507 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 418 451 0.0028 T 12-10-2018 IPR001451 Hexapeptide repeat UA74_03635 0842b6ff3bfb5aab07caa84992a5a1c0 507 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 341 374 3.8E-4 T 12-10-2018 IPR001451 Hexapeptide repeat UA74_03635 0842b6ff3bfb5aab07caa84992a5a1c0 507 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 18 475 39.835 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 UA74_03635 0842b6ff3bfb5aab07caa84992a5a1c0 507 Gene3D G3DSA:3.90.550.10 12 275 1.3E-73 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_03635 0842b6ff3bfb5aab07caa84992a5a1c0 507 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 20 476 4.4E-169 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 UA74_03635 0842b6ff3bfb5aab07caa84992a5a1c0 507 Pfam PF12804 MobA-like NTP transferase domain 22 167 1.0E-21 T 12-10-2018 IPR025877 MobA-like NTP transferase UA74_03635 0842b6ff3bfb5aab07caa84992a5a1c0 507 SUPERFAMILY SSF51161 268 461 3.87E-36 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily UA74_03635 0842b6ff3bfb5aab07caa84992a5a1c0 507 Gene3D G3DSA:2.160.10.10 276 463 2.1E-47 T 12-10-2018 UA74_19740 e6ecf9cf48dc9192d0282afaa881c619 285 SMART SM00530 20 75 3.4E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_19740 e6ecf9cf48dc9192d0282afaa881c619 285 Gene3D G3DSA:1.10.260.40 14 77 3.1E-8 T 12-10-2018 UA74_19740 e6ecf9cf48dc9192d0282afaa881c619 285 SUPERFAMILY SSF47413 16 74 6.22E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_19740 e6ecf9cf48dc9192d0282afaa881c619 285 Pfam PF13560 Helix-turn-helix domain 17 78 2.1E-11 T 12-10-2018 UA74_00955 9bb83ef24431b913f742324405739dbc 255 Gene3D G3DSA:3.20.20.60 2 255 4.1E-70 T 12-10-2018 UA74_00955 9bb83ef24431b913f742324405739dbc 255 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 240 3.3E-36 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 UA74_00955 9bb83ef24431b913f742324405739dbc 255 SUPERFAMILY SSF51621 6 252 7.07E-64 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UA74_29155 0c47207b54ae1fbebf5f95706ae69d11 211 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 47 210 34.195 T 12-10-2018 IPR022939 Uncharacterised protein family UPF0678 UA74_29155 0c47207b54ae1fbebf5f95706ae69d11 211 Gene3D G3DSA:2.40.128.20 17 211 5.6E-77 T 12-10-2018 IPR012674 Calycin UA74_29155 0c47207b54ae1fbebf5f95706ae69d11 211 Pfam PF08768 Domain of unknown function (DUF1794) 56 208 4.3E-48 T 12-10-2018 IPR014878 Domain of unknown function DUF1794 UA74_29155 0c47207b54ae1fbebf5f95706ae69d11 211 SUPERFAMILY SSF50814 50 209 8.12E-41 T 12-10-2018 IPR012674 Calycin UA74_17550 e5990b20c2ea281759ccda2713650b35 327 SUPERFAMILY SSF51735 3 317 1.1E-87 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17550 e5990b20c2ea281759ccda2713650b35 327 PRINTS PR01713 Nucleotide sugar epimerase signature 235 250 4.3E-5 T 12-10-2018 UA74_17550 e5990b20c2ea281759ccda2713650b35 327 PRINTS PR01713 Nucleotide sugar epimerase signature 212 227 4.3E-5 T 12-10-2018 UA74_17550 e5990b20c2ea281759ccda2713650b35 327 PRINTS PR01713 Nucleotide sugar epimerase signature 278 295 4.3E-5 T 12-10-2018 UA74_17550 e5990b20c2ea281759ccda2713650b35 327 Gene3D G3DSA:3.40.50.720 2 320 1.0E-94 T 12-10-2018 UA74_17550 e5990b20c2ea281759ccda2713650b35 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 241 7.7E-58 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_01900 b13e019e997e080be99a834cf3a7128d 288 SUPERFAMILY SSF53613 18 282 4.37E-71 T 12-10-2018 IPR029056 Ribokinase-like UA74_01900 b13e019e997e080be99a834cf3a7128d 288 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 21 279 1.5E-83 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_01900 b13e019e997e080be99a834cf3a7128d 288 Gene3D G3DSA:3.40.1190.20 13 287 1.3E-90 T 12-10-2018 IPR029056 Ribokinase-like UA74_01900 b13e019e997e080be99a834cf3a7128d 288 Pfam PF08543 Phosphomethylpyrimidine kinase 28 277 5.1E-81 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 UA74_19135 12724b6367d538c7162c4fcffb96b445 305 Gene3D G3DSA:3.40.50.720 1 305 5.2E-42 T 12-10-2018 UA74_19135 12724b6367d538c7162c4fcffb96b445 305 Pfam PF00106 short chain dehydrogenase 7 146 1.2E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19135 12724b6367d538c7162c4fcffb96b445 305 SUPERFAMILY SSF51735 5 231 1.42E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_13590 c74ba22b36e925ee8175c64f9e3daefa 245 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 6 234 37.295 T 12-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 UA74_13590 c74ba22b36e925ee8175c64f9e3daefa 245 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 8 233 5.8E-62 T 12-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 UA74_13590 c74ba22b36e925ee8175c64f9e3daefa 245 SUPERFAMILY SSF56784 8 234 5.79E-52 T 12-10-2018 IPR036412 HAD-like superfamily UA74_13590 c74ba22b36e925ee8175c64f9e3daefa 245 Gene3D G3DSA:1.10.720.60 21 105 7.9E-59 T 12-10-2018 UA74_13590 c74ba22b36e925ee8175c64f9e3daefa 245 Gene3D G3DSA:3.40.50.1000 10 216 7.9E-59 T 12-10-2018 IPR023214 HAD superfamily UA74_11560 d608e24c92b5773ea8dfe9c53690756f 277 Pfam PF11296 Protein of unknown function (DUF3097) 10 272 4.6E-119 T 12-10-2018 IPR021447 Protein of unknown function DUF3097 UA74_10390 22a4b1d96e263da5916f59aa8fca984e 298 Pfam PF00535 Glycosyl transferase family 2 7 111 5.2E-18 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_10390 22a4b1d96e263da5916f59aa8fca984e 298 SUPERFAMILY SSF53448 5 233 7.31E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_10390 22a4b1d96e263da5916f59aa8fca984e 298 Gene3D G3DSA:3.90.550.10 2 217 6.3E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_04200 4a14949c282cfcbc0aa182eaea942fc9 1028 SUPERFAMILY SSF52540 20 1011 1.7E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04200 4a14949c282cfcbc0aa182eaea942fc9 1028 Gene3D G3DSA:3.40.50.300 790 1026 4.4E-25 T 12-10-2018 UA74_04200 4a14949c282cfcbc0aa182eaea942fc9 1028 Gene3D G3DSA:3.40.50.300 1 351 2.4E-33 T 12-10-2018 UA74_04200 4a14949c282cfcbc0aa182eaea942fc9 1028 Pfam PF13476 AAA domain 5 184 7.5E-20 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain UA74_04200 4a14949c282cfcbc0aa182eaea942fc9 1028 Pfam PF13558 Putative exonuclease SbcCD, C subunit 925 986 5.7E-11 T 12-10-2018 UA74_18405 0667db49f14d24f46b8237622c9a525a 311 SUPERFAMILY SSF55120 83 295 5.44E-49 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_18405 0667db49f14d24f46b8237622c9a525a 311 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_18405 0667db49f14d24f46b8237622c9a525a 311 Pfam PF00849 RNA pseudouridylate synthase 99 245 1.9E-17 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_18405 0667db49f14d24f46b8237622c9a525a 311 Gene3D G3DSA:3.30.2350.10 83 297 4.5E-43 T 12-10-2018 UA74_00185 dafdca2006d30adfb53fdaff32c33222 1113 Pfam PF05141 Pyoverdine/dityrosine biosynthesis protein 765 878 3.3E-17 T 12-10-2018 IPR007817 Pyoverdine biosynthesis UA74_14610 ba79b47a64967804254d50999f9f46db 338 Gene3D G3DSA:3.20.20.100 1 324 1.8E-98 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_14610 ba79b47a64967804254d50999f9f46db 338 PRINTS PR00069 Aldo-keto reductase signature 105 123 6.8E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_14610 ba79b47a64967804254d50999f9f46db 338 PRINTS PR00069 Aldo-keto reductase signature 42 66 6.8E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_14610 ba79b47a64967804254d50999f9f46db 338 PRINTS PR00069 Aldo-keto reductase signature 136 153 6.8E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_14610 ba79b47a64967804254d50999f9f46db 338 SUPERFAMILY SSF51430 2 307 4.85E-82 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_14610 ba79b47a64967804254d50999f9f46db 338 Pfam PF00248 Aldo/keto reductase family 15 307 3.5E-63 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_25440 82f23f51eef5a92b679bd788d7549cd8 167 Pfam PF11343 Protein of unknown function (DUF3145) 10 165 1.4E-69 T 12-10-2018 IPR021491 Protein of unknown function DUF3145 UA74_24960 b65a323384ff9cc3b86980570ce1f20d 286 Pfam PF13560 Helix-turn-helix domain 13 75 8.7E-15 T 12-10-2018 UA74_24960 b65a323384ff9cc3b86980570ce1f20d 286 SMART SM00530 17 72 2.9E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_24960 b65a323384ff9cc3b86980570ce1f20d 286 Gene3D G3DSA:1.10.260.40 12 83 4.4E-10 T 12-10-2018 UA74_24960 b65a323384ff9cc3b86980570ce1f20d 286 SUPERFAMILY SSF47413 12 68 7.68E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_00880 8d6a92ed8875ed1f88d7d692ea656736 544 SUPERFAMILY SSF51679 7 289 2.52E-55 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_00880 8d6a92ed8875ed1f88d7d692ea656736 544 Gene3D G3DSA:3.20.20.30 8 299 1.4E-61 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_00880 8d6a92ed8875ed1f88d7d692ea656736 544 Pfam PF00296 Luciferase-like monooxygenase 19 230 2.2E-45 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_00880 8d6a92ed8875ed1f88d7d692ea656736 544 Pfam PF01814 Hemerythrin HHE cation binding domain 391 535 5.9E-17 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 UA74_00880 8d6a92ed8875ed1f88d7d692ea656736 544 Gene3D G3DSA:1.20.120.520 379 544 1.0E-29 T 12-10-2018 UA74_11015 18054f88d3d7cc68628fdf6974b66437 155 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 132 6.2E-12 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 UA74_11015 18054f88d3d7cc68628fdf6974b66437 155 SUPERFAMILY SSF55961 3 150 1.28E-33 T 12-10-2018 UA74_11015 18054f88d3d7cc68628fdf6974b66437 155 Gene3D G3DSA:3.30.530.20 1 154 2.9E-44 T 12-10-2018 IPR023393 START-like domain superfamily UA74_29585 0f4969dbdb7047afd104e3a3e343e2f7 543 SUPERFAMILY SSF103473 48 535 3.92E-65 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_29585 0f4969dbdb7047afd104e3a3e343e2f7 543 Pfam PF07690 Major Facilitator Superfamily 66 461 6.7E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_29585 0f4969dbdb7047afd104e3a3e343e2f7 543 PRINTS PR01036 Tetracycline resistance protein TetB signature 452 471 1.8E-6 T 12-10-2018 UA74_29585 0f4969dbdb7047afd104e3a3e343e2f7 543 PRINTS PR01036 Tetracycline resistance protein TetB signature 186 210 1.8E-6 T 12-10-2018 UA74_29585 0f4969dbdb7047afd104e3a3e343e2f7 543 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 147 1.8E-6 T 12-10-2018 UA74_29585 0f4969dbdb7047afd104e3a3e343e2f7 543 Gene3D G3DSA:1.20.1250.20 310 537 1.3E-15 T 12-10-2018 UA74_29585 0f4969dbdb7047afd104e3a3e343e2f7 543 Gene3D G3DSA:1.20.1720.10 64 290 1.0E-44 T 12-10-2018 UA74_28815 f8f15a1519c1c96377f0632961e80b87 181 Gene3D G3DSA:2.60.120.10 1 180 5.7E-54 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_28815 f8f15a1519c1c96377f0632961e80b87 181 SUPERFAMILY SSF51182 1 178 2.73E-55 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_28815 f8f15a1519c1c96377f0632961e80b87 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 7 173 7.0E-53 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_28815 f8f15a1519c1c96377f0632961e80b87 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 8 167 2.0E-45 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_27025 91e36d072ebbecd48dff4a3478e60ddf 408 PIRSF PIRSF037226 5 399 1.2E-133 T 12-10-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted UA74_27025 91e36d072ebbecd48dff4a3478e60ddf 408 SUPERFAMILY SSF53187 17 381 2.77E-58 T 12-10-2018 UA74_27025 91e36d072ebbecd48dff4a3478e60ddf 408 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 352 2.5E-57 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 UA74_27025 91e36d072ebbecd48dff4a3478e60ddf 408 SUPERFAMILY SSF55031 172 275 1.11E-18 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UA74_27025 91e36d072ebbecd48dff4a3478e60ddf 408 Gene3D G3DSA:3.40.630.10 26 367 3.3E-120 T 12-10-2018 UA74_27025 91e36d072ebbecd48dff4a3478e60ddf 408 Pfam PF07687 Peptidase dimerisation domain 169 266 8.6E-9 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain UA74_27025 91e36d072ebbecd48dff4a3478e60ddf 408 Gene3D G3DSA:3.30.70.360 170 287 3.3E-120 T 12-10-2018 UA74_27025 91e36d072ebbecd48dff4a3478e60ddf 408 Pfam PF01546 Peptidase family M20/M25/M40 94 348 3.7E-7 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 UA74_22570 2c539fc60f8d88b78738601f4219c019 122 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 79 2.5E-10 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 UA74_22570 2c539fc60f8d88b78738601f4219c019 122 SUPERFAMILY SSF53223 10 82 6.91E-11 T 12-10-2018 UA74_22570 2c539fc60f8d88b78738601f4219c019 122 Gene3D G3DSA:3.40.50.10860 7 114 3.7E-19 T 12-10-2018 UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 SUPERFAMILY SSF48452 657 826 2.17E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 SUPERFAMILY SSF52540 49 246 7.28E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 863 877 9.4E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 893 905 9.4E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 877 893 9.4E-5 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 Gene3D G3DSA:1.25.40.10 525 834 2.6E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 Gene3D G3DSA:1.10.10.10 848 919 8.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 Pfam PF00196 Bacterial regulatory proteins, luxR family 862 914 2.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 SUPERFAMILY SSF46894 851 917 1.77E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_16560 e6050944e1a39e4ff145e1a2cf51ef90 939 SMART SM00421 860 917 2.9E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 1.0E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.0E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 1.0E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 52 67 1.9E-19 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 32 50 1.9E-19 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 272 294 1.9E-19 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 97 110 1.9E-19 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 PRINTS PR00412 Epoxide hydrolase signature 111 124 1.9E-19 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 Gene3D G3DSA:3.40.50.1820 2 296 2.8E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 SUPERFAMILY SSF53474 9 296 1.79E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22345 0f0e95eeba5ed2bd0d61b03481d2b80e 301 Pfam PF00561 alpha/beta hydrolase fold 27 181 2.3E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 SUPERFAMILY SSF52374 2 286 6.97E-87 T 12-10-2018 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 Gene3D G3DSA:3.40.50.620 1 279 3.2E-115 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 Gene3D G3DSA:1.20.120.640 280 450 1.2E-33 T 12-10-2018 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 SMART SM00840 322 387 4.8E-9 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 Pfam PF09190 DALR domain 322 379 7.9E-7 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 3 14 2.1E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 197 218 2.1E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 39 48 2.1E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 166 184 2.1E-26 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 SUPERFAMILY SSF47323 310 449 4.58E-30 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 450 33.049 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 1 448 7.1E-130 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 UA74_01690 dc1cf466fa92fb5221377bfa234bf096 453 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 1 287 5.2E-119 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 UA74_28415 c02ac44021fc56fb43718c31a1e00a85 226 SUPERFAMILY SSF53955 40 120 9.09E-33 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_28415 c02ac44021fc56fb43718c31a1e00a85 226 SMART SM00257 180 226 5.2E-10 T 12-10-2018 IPR018392 LysM domain UA74_28415 c02ac44021fc56fb43718c31a1e00a85 226 Gene3D G3DSA:1.10.530.10 12 121 3.4E-38 T 12-10-2018 UA74_28415 c02ac44021fc56fb43718c31a1e00a85 226 SUPERFAMILY SSF54106 181 225 1.57E-8 T 12-10-2018 UA74_28415 c02ac44021fc56fb43718c31a1e00a85 226 Pfam PF06737 Transglycosylase-like domain 41 114 1.0E-35 T 12-10-2018 IPR010618 Transglycosylase-like UA74_28415 c02ac44021fc56fb43718c31a1e00a85 226 Gene3D G3DSA:3.10.350.10 180 224 4.5E-13 T 12-10-2018 IPR036779 LysM domain superfamily UA74_28415 c02ac44021fc56fb43718c31a1e00a85 226 Pfam PF01476 LysM domain 181 225 4.9E-12 T 12-10-2018 IPR018392 LysM domain UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 Pfam PF01245 Ribosomal protein L19 4 112 3.1E-50 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 3.0E-49 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 SUPERFAMILY SSF50104 1 114 1.0E-46 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 Gene3D G3DSA:2.30.30.790 3 114 2.4E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 PIRSF PIRSF002191 1 119 5.4E-51 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.3E-41 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.3E-41 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.3E-41 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 29.734 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08845 b0a9a74d3681d02a3f7f1112ed0a7169 119 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_06260 85471ada321582cd20fe3d8b1d4c9166 212 Gene3D G3DSA:3.90.950.10 3 207 2.6E-72 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like UA74_06260 85471ada321582cd20fe3d8b1d4c9166 212 Hamap MF_01405 dITP/XTP pyrophosphatase. 6 205 48.863 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 UA74_06260 85471ada321582cd20fe3d8b1d4c9166 212 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 8 200 3.0E-47 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 UA74_06260 85471ada321582cd20fe3d8b1d4c9166 212 Pfam PF01725 Ham1 family 8 200 2.0E-56 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 UA74_06260 85471ada321582cd20fe3d8b1d4c9166 212 SUPERFAMILY SSF52972 5 204 2.41E-62 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like UA74_26370 f1932fe86acfac9820fe625616db4b28 378 SMART SM00382 27 212 9.4E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_26370 f1932fe86acfac9820fe625616db4b28 378 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_26370 f1932fe86acfac9820fe625616db4b28 378 SUPERFAMILY SSF52540 2 239 3.08E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26370 f1932fe86acfac9820fe625616db4b28 378 Gene3D G3DSA:3.40.50.300 1 246 1.1E-70 T 12-10-2018 UA74_26370 f1932fe86acfac9820fe625616db4b28 378 Pfam PF00005 ABC transporter 19 163 2.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_28385 fddf509f9c0fd906d97961920dff7f70 197 SUPERFAMILY SSF46689 3 76 1.15E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_28385 fddf509f9c0fd906d97961920dff7f70 197 Gene3D G3DSA:1.10.357.10 2 183 4.5E-21 T 12-10-2018 UA74_28385 fddf509f9c0fd906d97961920dff7f70 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_28385 fddf509f9c0fd906d97961920dff7f70 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_28385 fddf509f9c0fd906d97961920dff7f70 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 51 4.2E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_09445 363e6392993aab474b4940a24f22370a 1113 PRINTS PR01950 LanC-like protein superfamily signature 1072 1089 7.0E-14 T 12-10-2018 IPR007822 Lanthionine synthetase C-like UA74_09445 363e6392993aab474b4940a24f22370a 1113 PRINTS PR01950 LanC-like protein superfamily signature 953 973 7.0E-14 T 12-10-2018 IPR007822 Lanthionine synthetase C-like UA74_09445 363e6392993aab474b4940a24f22370a 1113 PRINTS PR01950 LanC-like protein superfamily signature 718 736 7.0E-14 T 12-10-2018 IPR007822 Lanthionine synthetase C-like UA74_09445 363e6392993aab474b4940a24f22370a 1113 PRINTS PR01950 LanC-like protein superfamily signature 890 906 7.0E-14 T 12-10-2018 IPR007822 Lanthionine synthetase C-like UA74_09445 363e6392993aab474b4940a24f22370a 1113 PRINTS PR01950 LanC-like protein superfamily signature 832 847 7.0E-14 T 12-10-2018 IPR007822 Lanthionine synthetase C-like UA74_09445 363e6392993aab474b4940a24f22370a 1113 Gene3D G3DSA:1.50.10.10 646 1095 8.5E-37 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_09445 363e6392993aab474b4940a24f22370a 1113 Pfam PF13575 Domain of unknown function (DUF4135) 220 600 5.9E-105 T 12-10-2018 IPR025410 Lantibiotic biosynthesis protein, dehydration domain UA74_09445 363e6392993aab474b4940a24f22370a 1113 PIRSF PIRSF037228 164 1105 4.2E-175 T 12-10-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM UA74_09445 363e6392993aab474b4940a24f22370a 1113 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 167 1092 1.1E-232 T 12-10-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM UA74_09445 363e6392993aab474b4940a24f22370a 1113 SUPERFAMILY SSF158745 692 1102 1.26E-61 T 12-10-2018 UA74_09445 363e6392993aab474b4940a24f22370a 1113 SMART SM01260 715 1100 5.3E-56 T 12-10-2018 IPR007822 Lanthionine synthetase C-like UA74_09445 363e6392993aab474b4940a24f22370a 1113 Pfam PF05147 Lanthionine synthetase C-like protein 718 1100 7.8E-49 T 12-10-2018 IPR007822 Lanthionine synthetase C-like UA74_08900 b8d9bfdc8e9bb7f0aac1e6184ec3b608 347 SUPERFAMILY SSF53067 31 343 1.42E-62 T 12-10-2018 UA74_08900 b8d9bfdc8e9bb7f0aac1e6184ec3b608 347 ProSitePatterns PS01125 ROK family signature. 167 194 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_08900 b8d9bfdc8e9bb7f0aac1e6184ec3b608 347 Pfam PF00480 ROK family 34 339 2.6E-66 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_08900 b8d9bfdc8e9bb7f0aac1e6184ec3b608 347 Gene3D G3DSA:3.30.420.40 34 337 4.9E-96 T 12-10-2018 UA74_08900 b8d9bfdc8e9bb7f0aac1e6184ec3b608 347 Gene3D G3DSA:3.30.420.40 158 325 4.9E-96 T 12-10-2018 UA74_02380 578866789321f0db907ce5f741f7b411 196 Pfam PF00578 AhpC/TSA family 55 173 9.4E-15 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_02380 578866789321f0db907ce5f741f7b411 196 Gene3D G3DSA:3.40.30.10 45 194 6.4E-32 T 12-10-2018 UA74_02380 578866789321f0db907ce5f741f7b411 196 SUPERFAMILY SSF52833 54 195 2.13E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_02380 578866789321f0db907ce5f741f7b411 196 ProSitePatterns PS00194 Thioredoxin family active site. 82 100 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_20385 d306727b4ce64250970da2e956e6f695 1094 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 992 1065 1.9E-17 T 12-10-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain UA74_20385 d306727b4ce64250970da2e956e6f695 1094 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 369 537 1.2E-55 T 12-10-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal UA74_20385 d306727b4ce64250970da2e956e6f695 1094 SUPERFAMILY SSF49785 308 435 1.09E-5 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_20385 d306727b4ce64250970da2e956e6f695 1094 SUPERFAMILY SSF49265 72 159 3.71E-6 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 UA74_20385 d306727b4ce64250970da2e956e6f695 1094 Gene3D G3DSA:2.60.120.260 179 352 0.0 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_20385 d306727b4ce64250970da2e956e6f695 1094 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 550 650 1.1E-28 T 12-10-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain UA74_20385 d306727b4ce64250970da2e956e6f695 1094 SUPERFAMILY SSF48208 672 1056 3.74E-38 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_20385 d306727b4ce64250970da2e956e6f695 1094 Gene3D G3DSA:1.50.10.10 165 1089 0.0 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_20385 d306727b4ce64250970da2e956e6f695 1094 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 655 990 6.0E-99 T 12-10-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain UA74_20385 d306727b4ce64250970da2e956e6f695 1094 Gene3D G3DSA:2.60.40.10 51 160 2.2E-37 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_20385 d306727b4ce64250970da2e956e6f695 1094 PIRSF PIRSF010631 42 1094 7.2E-295 T 12-10-2018 IPR016007 Alpha-L-rhamnosidase UA74_03865 24c235c1f56d7b4afd4889b57a9c5392 255 SMART SM00346 5 96 1.9E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_03865 24c235c1f56d7b4afd4889b57a9c5392 255 Pfam PF01614 Bacterial transcriptional regulator 124 248 1.9E-33 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_03865 24c235c1f56d7b4afd4889b57a9c5392 255 Pfam PF09339 IclR helix-turn-helix domain 7 58 1.5E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_03865 24c235c1f56d7b4afd4889b57a9c5392 255 SUPERFAMILY SSF55781 72 251 4.38E-51 T 12-10-2018 UA74_03865 24c235c1f56d7b4afd4889b57a9c5392 255 Gene3D G3DSA:3.30.450.40 81 254 6.1E-58 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_03865 24c235c1f56d7b4afd4889b57a9c5392 255 SUPERFAMILY SSF46785 5 79 2.49E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_03865 24c235c1f56d7b4afd4889b57a9c5392 255 Gene3D G3DSA:1.10.10.10 3 80 1.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23710 bcf0a071e1929ea273dcd67aa8fd49cc 230 Gene3D G3DSA:3.30.70.1100 126 229 1.3E-35 T 12-10-2018 UA74_23710 bcf0a071e1929ea273dcd67aa8fd49cc 230 Pfam PF06778 Chlorite dismutase 32 220 4.2E-74 T 12-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase UA74_23710 bcf0a071e1929ea273dcd67aa8fd49cc 230 SUPERFAMILY SSF54909 5 229 9.65E-79 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_00735 2115658e05adacf0fb43310d609414ec 506 Pfam PF04389 Peptidase family M28 249 463 1.6E-36 T 12-10-2018 IPR007484 Peptidase M28 UA74_00735 2115658e05adacf0fb43310d609414ec 506 SUPERFAMILY SSF52025 116 233 8.11E-16 T 12-10-2018 UA74_00735 2115658e05adacf0fb43310d609414ec 506 Pfam PF02225 PA domain 138 226 1.3E-13 T 12-10-2018 IPR003137 PA domain UA74_00735 2115658e05adacf0fb43310d609414ec 506 Gene3D G3DSA:3.50.30.30 111 241 5.1E-79 T 12-10-2018 UA74_00735 2115658e05adacf0fb43310d609414ec 506 SUPERFAMILY SSF53187 47 469 6.86E-56 T 12-10-2018 UA74_00735 2115658e05adacf0fb43310d609414ec 506 Gene3D G3DSA:3.40.630.10 72 458 5.1E-79 T 12-10-2018 UA74_09115 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.1E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.1E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.1E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.1E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.1E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.1E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 SUPERFAMILY SSF51735 7 251 3.24E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_09115 ab281e36b07923d146e9a4c11a372682 254 Pfam PF00106 short chain dehydrogenase 12 194 4.7E-49 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.0E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09115 ab281e36b07923d146e9a4c11a372682 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 189 8.5E-5 T 12-10-2018 UA74_09115 ab281e36b07923d146e9a4c11a372682 254 Gene3D G3DSA:3.40.50.720 1 252 5.2E-70 T 12-10-2018 UA74_25525 00e42ee0df7606799d348336a7acc631 91 Pfam PF04149 Domain of unknown function (DUF397) 9 59 4.9E-22 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_29255 385752cafeace2f53d6f2c2897579c42 223 SMART SM01211 1 220 2.8E-119 T 12-10-2018 UA74_29255 385752cafeace2f53d6f2c2897579c42 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 203 1.2E-32 T 12-10-2018 UA74_29255 385752cafeace2f53d6f2c2897579c42 223 Gene3D G3DSA:3.40.50.880 1 221 1.2E-58 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_29255 385752cafeace2f53d6f2c2897579c42 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 4.1E-79 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_29255 385752cafeace2f53d6f2c2897579c42 223 PIRSF PIRSF001586 1 223 5.4E-76 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_29255 385752cafeace2f53d6f2c2897579c42 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 38.865 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_29255 385752cafeace2f53d6f2c2897579c42 223 SUPERFAMILY SSF52317 1 218 2.87E-67 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_22455 45c5a70ebebcd21aaed0bd82848218d6 155 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_22455 45c5a70ebebcd21aaed0bd82848218d6 155 Gene3D G3DSA:3.90.79.10 3 154 9.5E-20 T 12-10-2018 UA74_22455 45c5a70ebebcd21aaed0bd82848218d6 155 Pfam PF00293 NUDIX domain 6 148 1.2E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_22455 45c5a70ebebcd21aaed0bd82848218d6 155 SUPERFAMILY SSF55811 4 154 2.03E-20 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_06420 e50e196f47f51eab0116cb9fc69bb268 222 SUPERFAMILY SSF46689 16 91 2.77E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_06420 e50e196f47f51eab0116cb9fc69bb268 222 Gene3D G3DSA:1.10.357.10 79 221 2.8E-30 T 12-10-2018 UA74_06420 e50e196f47f51eab0116cb9fc69bb268 222 Gene3D G3DSA:1.10.10.60 13 69 1.6E-19 T 12-10-2018 UA74_06420 e50e196f47f51eab0116cb9fc69bb268 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 9.0E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06420 e50e196f47f51eab0116cb9fc69bb268 222 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 161 214 2.7E-11 T 12-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type UA74_06420 e50e196f47f51eab0116cb9fc69bb268 222 SUPERFAMILY SSF48498 101 212 3.26E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_06420 e50e196f47f51eab0116cb9fc69bb268 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06420 e50e196f47f51eab0116cb9fc69bb268 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 Pfam PF00067 Cytochrome P450 82 379 1.5E-18 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 SUPERFAMILY SSF48264 13 402 4.98E-85 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 156 171 1.1E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 326 341 1.1E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 89 100 1.1E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 281 292 1.1E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 139 155 1.1E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 199 221 1.1E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 298 325 1.1E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 347 356 1.1E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 PRINTS PR00359 B-class P450 signature 356 367 1.1E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_00450 75c4102239c8717e92c4a8ac92c79266 404 Gene3D G3DSA:1.10.630.10 4 404 6.7E-123 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 Pfam PF14759 Reductase C-terminal 342 410 1.4E-14 T 12-10-2018 IPR028202 Reductase, C-terminal UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 6.1E-20 T 12-10-2018 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 6.1E-20 T 12-10-2018 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.1E-20 T 12-10-2018 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 6.1E-20 T 12-10-2018 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 6.1E-20 T 12-10-2018 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 SUPERFAMILY SSF55424 338 409 2.06E-19 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 Gene3D G3DSA:3.50.50.60 4 315 1.2E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 SUPERFAMILY SSF51905 4 188 5.0E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 Gene3D G3DSA:3.50.50.60 113 253 1.2E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 Gene3D G3DSA:3.30.390.30 342 420 5.3E-15 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 315 1.5E-46 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.7E-15 T 12-10-2018 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 4.7E-15 T 12-10-2018 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 261 4.7E-15 T 12-10-2018 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 4.7E-15 T 12-10-2018 UA74_06580 f789c5b848af8cf3e58b2bd229f681a5 421 SUPERFAMILY SSF51905 144 323 4.59E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 376 4.0E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 Gene3D G3DSA:3.30.565.10 228 377 3.7E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 223 5.4E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 356 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1 12 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 332 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 375 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 SUPERFAMILY SSF158472 104 153 1.57E-7 T 12-10-2018 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 SMART SM00388 157 224 2.4E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 SUPERFAMILY SSF47384 140 222 9.22E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 Pfam PF00672 HAMP domain 104 152 2.5E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 SMART SM00387 267 378 4.0E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 SUPERFAMILY SSF55874 231 375 1.27E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 SMART SM00304 103 156 1.3E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_08515 999a45c078e664b969ab6288da4b5ca1 378 Gene3D G3DSA:1.10.287.130 107 224 2.2E-28 T 12-10-2018 UA74_17275 14590349e2dd22d70b7b00cd978e1a76 236 Gene3D G3DSA:3.40.50.150 9 220 6.4E-79 T 12-10-2018 UA74_17275 14590349e2dd22d70b7b00cd978e1a76 236 Gene3D G3DSA:2.20.130.10 146 204 6.4E-79 T 12-10-2018 UA74_17275 14590349e2dd22d70b7b00cd978e1a76 236 Pfam PF13649 Methyltransferase domain 43 133 2.3E-14 T 12-10-2018 UA74_17275 14590349e2dd22d70b7b00cd978e1a76 236 SUPERFAMILY SSF53335 6 222 2.37E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_28500 6e84b01c992feed8b267039678c8f74e 553 SUPERFAMILY SSF52540 146 345 2.85E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28500 6e84b01c992feed8b267039678c8f74e 553 SMART SM00490 423 500 1.1E-12 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_28500 6e84b01c992feed8b267039678c8f74e 553 Gene3D G3DSA:3.40.50.300 172 353 1.2E-36 T 12-10-2018 UA74_28500 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 356 378 2.4E-34 T 12-10-2018 UA74_28500 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 456 474 2.4E-34 T 12-10-2018 UA74_28500 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 475 500 2.4E-34 T 12-10-2018 UA74_28500 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 291 311 2.4E-34 T 12-10-2018 UA74_28500 6e84b01c992feed8b267039678c8f74e 553 PRINTS PR00851 Xeroderma pigmentosum group B protein signature 191 213 2.4E-34 T 12-10-2018 UA74_28500 6e84b01c992feed8b267039678c8f74e 553 SUPERFAMILY SSF52540 284 527 6.57E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28500 6e84b01c992feed8b267039678c8f74e 553 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 540 3.0E-45 T 12-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 UA74_28500 6e84b01c992feed8b267039678c8f74e 553 Gene3D G3DSA:3.40.50.300 354 545 1.4E-47 T 12-10-2018 UA74_28500 6e84b01c992feed8b267039678c8f74e 553 Pfam PF13625 Helicase conserved C-terminal domain 6 133 1.3E-44 T 12-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 UA74_28500 6e84b01c992feed8b267039678c8f74e 553 SMART SM00487 178 353 3.4E-22 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_28500 6e84b01c992feed8b267039678c8f74e 553 Pfam PF04851 Type III restriction enzyme, res subunit 181 326 1.8E-14 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_16245 6870b5c2fde051cfbfef27239962a695 376 Pfam PF12666 PrgI family protein 6 93 1.9E-14 T 12-10-2018 IPR024414 Uncharacterised protein family PrgI UA74_16965 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:3.30.300.30 887 988 4.3E-28 T 12-10-2018 UA74_16965 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:3.40.50.12780 472 886 1.7E-106 T 12-10-2018 UA74_16965 d418d360adf525cc670860d4ad1800db 1080 Pfam PF13193 AMP-binding enzyme C-terminal domain 901 974 6.3E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_16965 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:3.30.559.30 239 460 3.9E-52 T 12-10-2018 UA74_16965 d418d360adf525cc670860d4ad1800db 1080 Pfam PF00550 Phosphopantetheine attachment site 1006 1069 5.9E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16965 d418d360adf525cc670860d4ad1800db 1080 SUPERFAMILY SSF52777 20 194 8.12E-31 T 12-10-2018 UA74_16965 d418d360adf525cc670860d4ad1800db 1080 SUPERFAMILY SSF56801 474 1017 1.57E-118 T 12-10-2018 UA74_16965 d418d360adf525cc670860d4ad1800db 1080 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 506 914 4.8E-96 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_16965 d418d360adf525cc670860d4ad1800db 1080 SUPERFAMILY SSF47336 997 1070 1.01E-17 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16965 d418d360adf525cc670860d4ad1800db 1080 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1028 1043 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16965 d418d360adf525cc670860d4ad1800db 1080 Pfam PF00668 Condensation domain 19 468 1.9E-48 T 12-10-2018 IPR001242 Condensation domain UA74_16965 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:3.30.559.10 20 217 1.1E-48 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_16965 d418d360adf525cc670860d4ad1800db 1080 SUPERFAMILY SSF52777 199 457 9.45E-31 T 12-10-2018 UA74_16965 d418d360adf525cc670860d4ad1800db 1080 SMART SM00823 Phosphopantetheine attachment site 1004 1073 8.7E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16965 d418d360adf525cc670860d4ad1800db 1080 ProSitePatterns PS00455 Putative AMP-binding domain signature. 633 644 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_16965 d418d360adf525cc670860d4ad1800db 1080 Pfam PF00501 AMP-binding enzyme 486 892 1.4E-76 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_16965 d418d360adf525cc670860d4ad1800db 1080 Gene3D G3DSA:3.40.50.1820 993 1079 4.0E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_30160 7f45d460bd218cb5e8b45221ae6f5f5c 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 317 4.2E-49 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 SMART SM00278 11 30 0.0081 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 SUPERFAMILY SSF111304 2 202 3.92E-68 T 12-10-2018 IPR023627 Recombination protein RecR UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 Gene3D G3DSA:1.10.8.420 1 51 9.5E-20 T 12-10-2018 UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 100.389 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 Pfam PF13662 Toprim domain 80 175 6.4E-22 T 12-10-2018 IPR006171 TOPRIM domain UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 SMART SM00493 79 168 3.8E-15 T 12-10-2018 IPR006171 TOPRIM domain UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 Pfam PF02132 RecR protein 38 77 2.5E-13 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 TIGRFAM TIGR00615 recR: recombination protein RecR 2 200 8.5E-79 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 UA74_01030 60836c8ddd590a2e77c6d7b292e645de 202 Gene3D G3DSA:3.40.1360.10 76 202 3.4E-42 T 12-10-2018 UA74_00580 82ef7a8ca50c8d4c96262fbe1bc2c036 204 Pfam PF01661 Macro domain 64 190 5.0E-12 T 12-10-2018 IPR002589 Macro domain UA74_00580 82ef7a8ca50c8d4c96262fbe1bc2c036 204 Gene3D G3DSA:3.40.220.10 14 202 9.9E-39 T 12-10-2018 UA74_00580 82ef7a8ca50c8d4c96262fbe1bc2c036 204 SUPERFAMILY SSF52949 24 199 1.08E-25 T 12-10-2018 UA74_00580 82ef7a8ca50c8d4c96262fbe1bc2c036 204 SMART SM00506 47 192 6.1E-12 T 12-10-2018 IPR002589 Macro domain UA74_01475 4ec1b4aa47318faa96a0de1aee75b382 591 SMART SM00776 432 589 7.1E-50 T 12-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module UA74_01475 4ec1b4aa47318faa96a0de1aee75b382 591 Pfam PF00149 Calcineurin-like phosphoesterase 38 250 2.1E-14 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UA74_01475 4ec1b4aa47318faa96a0de1aee75b382 591 Gene3D G3DSA:3.60.21.10 41 306 5.8E-18 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_01475 4ec1b4aa47318faa96a0de1aee75b382 591 Gene3D G3DSA:2.60.120.1060 430 588 8.4E-43 T 12-10-2018 IPR038637 NPCBM domain superfamily UA74_01475 4ec1b4aa47318faa96a0de1aee75b382 591 SUPERFAMILY SSF56300 39 306 3.48E-31 T 12-10-2018 UA74_01475 4ec1b4aa47318faa96a0de1aee75b382 591 Pfam PF08305 NPCBM/NEW2 domain 435 587 1.3E-40 T 12-10-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module UA74_01475 4ec1b4aa47318faa96a0de1aee75b382 591 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 334 401 3.9E-8 T 12-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain UA74_01475 4ec1b4aa47318faa96a0de1aee75b382 591 SUPERFAMILY SSF49785 435 587 3.53E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_21540 354b02251f3e7ee91719e713b2ec3c1d 583 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 570 2.3E-170 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 UA74_21540 354b02251f3e7ee91719e713b2ec3c1d 583 SUPERFAMILY SSF52540 2 217 2.26E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21540 354b02251f3e7ee91719e713b2ec3c1d 583 Gene3D G3DSA:3.40.50.300 286 571 2.6E-50 T 12-10-2018 UA74_21540 354b02251f3e7ee91719e713b2ec3c1d 583 Gene3D G3DSA:3.40.50.300 1 250 2.8E-35 T 12-10-2018 UA74_21540 354b02251f3e7ee91719e713b2ec3c1d 583 PIRSF PIRSF003128 1 575 8.1E-150 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 UA74_21540 354b02251f3e7ee91719e713b2ec3c1d 583 Pfam PF02463 RecF/RecN/SMC N terminal domain 11 525 2.9E-13 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal UA74_21540 354b02251f3e7ee91719e713b2ec3c1d 583 SUPERFAMILY SSF52540 2 528 5.55E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25300 4336e6db97a87833341042b8b2a7a5d9 418 Pfam PF09661 Protein of unknown function (DUF2398) 34 384 2.9E-93 T 12-10-2018 IPR013494 Conserved hypothetical protein CHP02678 UA74_25300 4336e6db97a87833341042b8b2a7a5d9 418 TIGRFAM TIGR02678 TIGR02678: TIGR02678 family protein 34 382 9.5E-39 T 12-10-2018 IPR013494 Conserved hypothetical protein CHP02678 UA74_24355 964e68df0fd1e5d7d2510ab7fe51f802 343 Gene3D G3DSA:3.10.450.50 191 341 4.3E-8 T 12-10-2018 UA74_24355 964e68df0fd1e5d7d2510ab7fe51f802 343 SUPERFAMILY SSF54427 193 340 4.83E-15 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_24355 964e68df0fd1e5d7d2510ab7fe51f802 343 Pfam PF04542 Sigma-70 region 2 24 90 3.4E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_24355 964e68df0fd1e5d7d2510ab7fe51f802 343 Gene3D G3DSA:1.10.10.10 131 187 9.9E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24355 964e68df0fd1e5d7d2510ab7fe51f802 343 Pfam PF08281 Sigma-70, region 4 136 181 7.2E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_24355 964e68df0fd1e5d7d2510ab7fe51f802 343 SUPERFAMILY SSF88946 10 110 7.46E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_24355 964e68df0fd1e5d7d2510ab7fe51f802 343 Gene3D G3DSA:1.10.1740.10 2 89 7.2E-10 T 12-10-2018 UA74_24355 964e68df0fd1e5d7d2510ab7fe51f802 343 SUPERFAMILY SSF88659 129 183 3.55E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_24355 964e68df0fd1e5d7d2510ab7fe51f802 343 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 181 1.3E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_28575 110ab89986736c015793859d2ce080c6 781 SMART SM01073 3 91 3.1E-14 T 12-10-2018 IPR003338 CDC48, N-terminal subdomain UA74_28575 110ab89986736c015793859d2ce080c6 781 ProSitePatterns PS00674 AAA-protein family signature. 658 676 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 UA74_28575 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:2.40.40.20 3 91 5.2E-7 T 12-10-2018 UA74_28575 110ab89986736c015793859d2ce080c6 781 SMART SM00382 553 690 2.5E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28575 110ab89986736c015793859d2ce080c6 781 SMART SM00382 289 423 0.0044 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28575 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:3.40.50.300 251 422 1.7E-21 T 12-10-2018 UA74_28575 110ab89986736c015793859d2ce080c6 781 SUPERFAMILY SSF50692 14 89 2.36E-9 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily UA74_28575 110ab89986736c015793859d2ce080c6 781 SUPERFAMILY SSF52540 518 774 3.83E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28575 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:3.40.50.300 518 775 9.6E-87 T 12-10-2018 UA74_28575 110ab89986736c015793859d2ce080c6 781 SUPERFAMILY SSF52540 255 504 5.27E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28575 110ab89986736c015793859d2ce080c6 781 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 12 90 2.2E-12 T 12-10-2018 IPR003338 CDC48, N-terminal subdomain UA74_28575 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:1.10.8.60 423 514 2.0E-16 T 12-10-2018 UA74_28575 110ab89986736c015793859d2ce080c6 781 Gene3D G3DSA:1.10.8.60 689 761 9.6E-87 T 12-10-2018 UA74_28575 110ab89986736c015793859d2ce080c6 781 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 293 417 2.4E-12 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_28575 110ab89986736c015793859d2ce080c6 781 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 557 687 4.4E-40 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_07585 d00b3d92616f59d740efc4f755e52a5f 200 Gene3D G3DSA:3.40.50.880 11 200 5.8E-29 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_07585 d00b3d92616f59d740efc4f755e52a5f 200 SUPERFAMILY SSF52317 15 198 3.51E-20 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_07585 d00b3d92616f59d740efc4f755e52a5f 200 Pfam PF01965 DJ-1/PfpI family 16 193 1.2E-13 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UA74_07995 6a8630885e489d113f2d01cff2dbbf7c 406 Pfam PF13530 Sterol carrier protein domain 181 402 4.7E-44 T 12-10-2018 IPR025559 Enhanced intracellular survival protein domain UA74_07995 6a8630885e489d113f2d01cff2dbbf7c 406 Hamap MF_01812 N-acetyltransferase Eis [eis]. 5 406 30.69 T 12-10-2018 IPR022902 N-acetyltransferase Eis UA74_07995 6a8630885e489d113f2d01cff2dbbf7c 406 Pfam PF13527 Acetyltransferase (GNAT) domain 8 132 1.2E-25 T 12-10-2018 UA74_07995 6a8630885e489d113f2d01cff2dbbf7c 406 SUPERFAMILY SSF55718 300 403 2.55E-21 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily UA74_07995 6a8630885e489d113f2d01cff2dbbf7c 406 Gene3D G3DSA:3.40.630.30 142 292 2.8E-33 T 12-10-2018 UA74_07995 6a8630885e489d113f2d01cff2dbbf7c 406 SUPERFAMILY SSF55729 9 299 2.08E-44 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_07995 6a8630885e489d113f2d01cff2dbbf7c 406 Gene3D G3DSA:3.30.1050.10 298 397 8.9E-28 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily UA74_07995 6a8630885e489d113f2d01cff2dbbf7c 406 Gene3D G3DSA:3.40.630.30 4 138 2.0E-30 T 12-10-2018 UA74_15560 aa189177b6334a942afe7187107b6af8 371 Gene3D G3DSA:3.20.20.70 1 368 1.5E-125 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_15560 aa189177b6334a942afe7187107b6af8 371 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 350 4.6E-72 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 UA74_15560 aa189177b6334a942afe7187107b6af8 371 SUPERFAMILY SSF51395 2 364 6.48E-114 T 12-10-2018 UA74_08300 dbd2d7c1cb873d80aa777a167bad0f84 86 SUPERFAMILY SSF46992 3 86 1.05E-27 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08300 dbd2d7c1cb873d80aa777a167bad0f84 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 83 2.9E-22 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08300 dbd2d7c1cb873d80aa777a167bad0f84 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 3.0E-23 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08300 dbd2d7c1cb873d80aa777a167bad0f84 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.595 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08300 dbd2d7c1cb873d80aa777a167bad0f84 86 Pfam PF01649 Ribosomal protein S20 2 84 1.8E-26 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08300 dbd2d7c1cb873d80aa777a167bad0f84 86 Gene3D G3DSA:1.20.58.110 1 86 9.0E-28 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_27130 7c584a4f1db2e030292920c7bdd601f8 365 Gene3D G3DSA:3.30.565.10 246 365 1.9E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_27130 7c584a4f1db2e030292920c7bdd601f8 365 Pfam PF07730 Histidine kinase 184 247 1.6E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_27130 7c584a4f1db2e030292920c7bdd601f8 365 SUPERFAMILY SSF55874 251 364 1.92E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 SMART SM01002 149 297 2.2E-80 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 Gene3D G3DSA:3.40.50.720 130 305 4.2E-137 T 12-10-2018 UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 Gene3D G3DSA:3.40.50.720 3 353 4.2E-137 T 12-10-2018 UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 PIRSF PIRSF000183 1 371 7.0E-159 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 SUPERFAMILY SSF51735 137 303 1.03E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 SMART SM01003 4 137 2.1E-79 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 365 2.1E-159 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 137 2.8E-47 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 SUPERFAMILY SSF52283 1 359 2.3E-65 T 12-10-2018 UA74_26245 a0586db09b79514f73f104bc52b56fe5 375 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 9.3E-78 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_17135 dcef9e052e5791b3c9cf9ed42a1d8691 553 Pfam PF13454 FAD-NAD(P)-binding 4 163 2.2E-34 T 12-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain UA74_17135 dcef9e052e5791b3c9cf9ed42a1d8691 553 SUPERFAMILY SSF51905 1 212 2.33E-9 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_19190 1ab458b71b7320e2dcb3895f1b809962 466 Pfam PF02386 Cation transport protein 45 444 3.7E-54 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 UA74_06105 c31de44c7eed8bbba7a3a252ffb32ca0 169 Gene3D G3DSA:1.10.10.10 1 158 1.2E-52 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_06105 c31de44c7eed8bbba7a3a252ffb32ca0 169 SUPERFAMILY SSF46785 5 144 3.1E-40 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_06105 c31de44c7eed8bbba7a3a252ffb32ca0 169 Pfam PF01638 HxlR-like helix-turn-helix 19 104 3.4E-23 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 Gene3D G3DSA:1.10.10.10 46 123 6.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 Pfam PF07729 FCD domain 137 257 8.0E-26 T 12-10-2018 IPR011711 GntR, C-terminal UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 SUPERFAMILY SSF48008 134 265 8.89E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 SMART SM00345 52 111 2.5E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 Pfam PF00392 Bacterial regulatory proteins, gntR family 50 111 3.4E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 71 85 5.4E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 85 101 5.4E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 Gene3D G3DSA:1.20.120.530 124 267 7.1E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 SUPERFAMILY SSF46785 45 115 1.55E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18250 49f616caad9da4fc6a9438906e5fedab 271 SMART SM00895 137 259 5.2E-21 T 12-10-2018 IPR011711 GntR, C-terminal UA74_13680 224df53e706b9ec469635f1d91127cf7 430 SMART SM00387 169 280 6.0E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_13680 224df53e706b9ec469635f1d91127cf7 430 Gene3D G3DSA:1.10.287.130 83 127 1.3E-16 T 12-10-2018 UA74_13680 224df53e706b9ec469635f1d91127cf7 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 173 277 1.4E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_13680 224df53e706b9ec469635f1d91127cf7 430 Gene3D G3DSA:3.30.565.10 128 276 1.3E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_13680 224df53e706b9ec469635f1d91127cf7 430 SUPERFAMILY SSF55874 162 279 5.24E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_17045 155dd9600a91a666dc94572bb00286ed 573 Gene3D G3DSA:3.10.105.10 325 538 7.6E-55 T 12-10-2018 UA74_17045 155dd9600a91a666dc94572bb00286ed 573 Gene3D G3DSA:3.40.190.10 55 324 7.1E-41 T 12-10-2018 UA74_17045 155dd9600a91a666dc94572bb00286ed 573 SUPERFAMILY SSF53850 53 556 3.98E-86 T 12-10-2018 UA74_17045 155dd9600a91a666dc94572bb00286ed 573 PIRSF PIRSF002741 4 566 1.7E-62 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_17045 155dd9600a91a666dc94572bb00286ed 573 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 99 482 3.0E-60 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_01435 6fab7d1510611f8d89eb8234a29f0ae1 770 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 27 717 5.9E-206 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UA74_01435 6fab7d1510611f8d89eb8234a29f0ae1 770 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 22 716 24.094 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UA74_01435 6fab7d1510611f8d89eb8234a29f0ae1 770 PIRSF PIRSF001265 19 724 1.1E-247 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UA74_01435 6fab7d1510611f8d89eb8234a29f0ae1 770 Pfam PF03030 Inorganic H+ pyrophosphatase 34 711 5.1E-237 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UA74_13495 7a4a160a255e6a5745b85384698da406 367 SUPERFAMILY SSF56112 33 339 9.77E-53 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_13495 7a4a160a255e6a5745b85384698da406 367 Gene3D G3DSA:3.90.1200.10 142 365 5.0E-63 T 12-10-2018 UA74_13495 7a4a160a255e6a5745b85384698da406 367 Pfam PF01636 Phosphotransferase enzyme family 57 276 4.1E-42 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_13495 7a4a160a255e6a5745b85384698da406 367 Gene3D G3DSA:3.30.200.20 34 136 6.5E-29 T 12-10-2018 UA74_25880 a25a961146a598be6afc90abe910b493 429 Gene3D G3DSA:3.50.50.60 235 371 6.1E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_25880 a25a961146a598be6afc90abe910b493 429 Gene3D G3DSA:3.50.50.60 4 201 1.1E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_25880 a25a961146a598be6afc90abe910b493 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 8.7E-22 T 12-10-2018 UA74_25880 a25a961146a598be6afc90abe910b493 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 8.7E-22 T 12-10-2018 UA74_25880 a25a961146a598be6afc90abe910b493 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 8.7E-22 T 12-10-2018 UA74_25880 a25a961146a598be6afc90abe910b493 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 8.7E-22 T 12-10-2018 UA74_25880 a25a961146a598be6afc90abe910b493 429 Pfam PF01494 FAD binding domain 14 322 1.0E-53 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_25880 a25a961146a598be6afc90abe910b493 429 SUPERFAMILY SSF51905 15 366 4.08E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_03475 f9dfc425a9c321d1bd2892932450cbb3 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 1.5E-19 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_04945 5f9897832c6a8935622fc713d459b028 319 Pfam PF00296 Luciferase-like monooxygenase 17 293 9.0E-38 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_04945 5f9897832c6a8935622fc713d459b028 319 SUPERFAMILY SSF51679 18 313 4.37E-42 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_04945 5f9897832c6a8935622fc713d459b028 319 Gene3D G3DSA:3.20.20.30 7 315 4.4E-55 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_09810 8809aa5d6acb0299c80823996f2d541f 340 Gene3D G3DSA:3.20.20.70 26 334 3.2E-94 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_09810 8809aa5d6acb0299c80823996f2d541f 340 SMART SM00876 241 333 4.1E-28 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_09810 8809aa5d6acb0299c80823996f2d541f 340 Pfam PF04055 Radical SAM superfamily 70 229 1.9E-11 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_09810 8809aa5d6acb0299c80823996f2d541f 340 TIGRFAM TIGR00433 bioB: biotin synthase 35 330 5.2E-102 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_09810 8809aa5d6acb0299c80823996f2d541f 340 SUPERFAMILY SSF102114 25 319 9.94E-61 T 12-10-2018 UA74_09810 8809aa5d6acb0299c80823996f2d541f 340 Hamap MF_01694 Biotin synthase [bioB]. 11 334 36.982 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_09810 8809aa5d6acb0299c80823996f2d541f 340 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 241 329 9.1E-13 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_09810 8809aa5d6acb0299c80823996f2d541f 340 PIRSF PIRSF001619 5 339 1.2E-99 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UA74_09810 8809aa5d6acb0299c80823996f2d541f 340 SMART SM00729 63 270 1.6E-32 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_05640 6fad308e79869010cf6f77067c535023 235 Gene3D G3DSA:3.30.1310.10 9 105 3.8E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_05640 6fad308e79869010cf6f77067c535023 235 SUPERFAMILY SSF82607 12 97 2.35E-6 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_05640 6fad308e79869010cf6f77067c535023 235 Pfam PF02575 YbaB/EbfC DNA-binding family 14 98 9.9E-10 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_06015 aeff210b8431f3543764cbb30f2b6705 305 Gene3D G3DSA:3.40.50.720 3 270 2.4E-44 T 12-10-2018 UA74_06015 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 8.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06015 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06015 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 8.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06015 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 8.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06015 aeff210b8431f3543764cbb30f2b6705 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 8.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06015 aeff210b8431f3543764cbb30f2b6705 305 Pfam PF00106 short chain dehydrogenase 8 209 1.3E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_06015 aeff210b8431f3543764cbb30f2b6705 305 SUPERFAMILY SSF51735 3 252 1.18E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_07725 45644b72601bf9e93377383a6e22eaa8 250 Pfam PF03704 Bacterial transcriptional activator domain 97 239 2.4E-39 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_07725 45644b72601bf9e93377383a6e22eaa8 250 SMART SM01043 96 240 6.0E-40 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_07725 45644b72601bf9e93377383a6e22eaa8 250 Gene3D G3DSA:1.10.10.10 1 91 3.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_07725 45644b72601bf9e93377383a6e22eaa8 250 SUPERFAMILY SSF48452 92 243 6.83E-29 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_07725 45644b72601bf9e93377383a6e22eaa8 250 Gene3D G3DSA:1.25.40.10 93 250 1.2E-41 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_07725 45644b72601bf9e93377383a6e22eaa8 250 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 78 1.9E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_07725 45644b72601bf9e93377383a6e22eaa8 250 SUPERFAMILY SSF46894 2 89 1.47E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_07725 45644b72601bf9e93377383a6e22eaa8 250 SMART SM00862 16 89 4.7E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF05000 RNA polymerase Rpb1, domain 4 753 820 7.1E-8 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 5.7E-80 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Gene3D G3DSA:1.10.132.30 718 852 6.7E-49 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 SMART SM00663 310 589 6.3E-172 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Gene3D G3DSA:1.10.1790.20 1011 1200 1.5E-62 T 12-10-2018 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1263 17.444 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Gene3D G3DSA:1.10.274.100 565 717 4.0E-40 T 12-10-2018 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Gene3D G3DSA:2.40.50.100 1027 1101 1.5E-62 T 12-10-2018 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Gene3D G3DSA:1.10.150.390 1202 1265 2.4E-29 T 12-10-2018 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF04998 RNA polymerase Rpb1, domain 5 828 1201 1.5E-64 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 467 560 2.3E-28 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 461 3.5E-8 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1253 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Gene3D G3DSA:1.10.40.90 449 491 1.8E-23 T 12-10-2018 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 SUPERFAMILY SSF64484 5 1255 0.0 T 12-10-2018 UA74_02865 16d59e6bd17423fa2ff9a0309c3f10aa 1303 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 721 1.2E-25 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_15400 03f98023b10759d3dd7f07be5614daa9 240 Pfam PF08241 Methyltransferase domain 49 141 9.1E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_15400 03f98023b10759d3dd7f07be5614daa9 240 Gene3D G3DSA:3.40.50.150 4 218 3.5E-47 T 12-10-2018 UA74_15400 03f98023b10759d3dd7f07be5614daa9 240 SUPERFAMILY SSF53335 10 216 4.42E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PIRSF PIRSF006431 1 323 4.4E-113 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 4.9E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 4.9E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 4.9E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 310 6.9E-92 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 1.1E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 111 125 1.1E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 1.1E-13 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 SUPERFAMILY SSF53474 3 319 7.54E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 Pfam PF00561 alpha/beta hydrolase fold 35 303 8.5E-34 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_18045 aff45c8a99d5c128b7f1ef58d9c9c2f3 324 Gene3D G3DSA:3.40.50.1820 1 322 1.8E-89 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 579 4.7E-207 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 5.9E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 5.9E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 5.9E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 5.9E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 SUPERFAMILY SSF55681 115 583 8.71E-98 T 12-10-2018 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 SUPERFAMILY SSF50249 2 104 1.14E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 7.1E-16 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 Pfam PF02938 GAD domain 313 394 2.5E-13 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 584 31.828 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 Gene3D G3DSA:3.30.930.10 117 580 2.2E-178 T 12-10-2018 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 Gene3D G3DSA:3.30.1360.30 273 412 2.2E-178 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 Gene3D G3DSA:2.40.50.140 1 107 4.1E-33 T 12-10-2018 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 557 1.5E-99 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_11990 eead80e000d136a3e2752a4b9dbe802e 590 SUPERFAMILY SSF55261 290 412 1.18E-33 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 Pfam PF00005 ABC transporter 1024 1173 7.6E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 ProSitePatterns PS00211 ABC transporters family signature. 457 471 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 Pfam PF00005 ABC transporter 332 485 8.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 SUPERFAMILY SSF52540 308 553 6.35E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26270 b609e89685bce16d7619543ff58269f6 1254 Gene3D G3DSA:3.40.50.300 1000 1253 1.6E-85 T 12-10-2018 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 Gene3D G3DSA:3.40.50.300 313 566 4.6E-81 T 12-10-2018 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 Pfam PF00664 ABC transporter transmembrane region 690 960 4.0E-38 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 Pfam PF00664 ABC transporter transmembrane region 1 269 1.7E-35 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 SUPERFAMILY SSF90123 2 304 1.7E-64 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 SUPERFAMILY SSF90123 674 993 7.85E-75 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 Gene3D G3DSA:1.20.1560.10 1 297 3.6E-68 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_26270 b609e89685bce16d7619543ff58269f6 1254 SMART SM00382 341 539 5.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_26270 b609e89685bce16d7619543ff58269f6 1254 SMART SM00382 1033 1219 9.2E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_26270 b609e89685bce16d7619543ff58269f6 1254 SUPERFAMILY SSF52540 998 1242 1.7E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26270 b609e89685bce16d7619543ff58269f6 1254 Gene3D G3DSA:1.20.1560.10 659 993 1.7E-81 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_16110 ab124ad72d6410b3e4e91a58e8969429 472 SUPERFAMILY SSF52540 102 402 1.53E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16110 ab124ad72d6410b3e4e91a58e8969429 472 Pfam PF00437 Type II/IV secretion system protein 119 402 3.0E-48 T 12-10-2018 IPR001482 Type II/IV secretion system protein UA74_16110 ab124ad72d6410b3e4e91a58e8969429 472 Gene3D G3DSA:3.40.50.300 219 453 1.7E-55 T 12-10-2018 UA74_16110 ab124ad72d6410b3e4e91a58e8969429 472 Gene3D G3DSA:3.30.450.380 23 215 2.8E-13 T 12-10-2018 UA74_20475 67a88083db0d2a391079c14414fd7a59 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_20475 67a88083db0d2a391079c14414fd7a59 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_20475 67a88083db0d2a391079c14414fd7a59 336 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_20475 67a88083db0d2a391079c14414fd7a59 336 Gene3D G3DSA:3.40.50.1820 4 266 4.2E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20475 67a88083db0d2a391079c14414fd7a59 336 Pfam PF00561 alpha/beta hydrolase fold 27 140 1.0E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_20475 67a88083db0d2a391079c14414fd7a59 336 SUPERFAMILY SSF53474 5 262 6.69E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19780 62da5446771938380bf3e77365c3ae4a 116 Pfam PF12840 Helix-turn-helix domain 26 83 3.6E-12 T 12-10-2018 UA74_19780 62da5446771938380bf3e77365c3ae4a 116 Gene3D G3DSA:1.10.10.10 5 116 2.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19780 62da5446771938380bf3e77365c3ae4a 116 SMART SM00418 25 103 3.8E-22 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19780 62da5446771938380bf3e77365c3ae4a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.3E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19780 62da5446771938380bf3e77365c3ae4a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 1.3E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19780 62da5446771938380bf3e77365c3ae4a 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 1.3E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19780 62da5446771938380bf3e77365c3ae4a 116 SUPERFAMILY SSF46785 14 100 4.82E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 SUPERFAMILY SSF52317 9 196 3.99E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00096 Glutamine amidotransferase superfamily signature 172 185 2.4E-13 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00096 Glutamine amidotransferase superfamily signature 82 93 2.4E-13 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 2.4E-13 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 Gene3D G3DSA:3.40.50.880 9 200 2.7E-61 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 3.1E-7 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 82 98 3.1E-7 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00097 Anthranilate synthase component II signature 107 115 7.4E-35 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00097 Anthranilate synthase component II signature 54 63 7.4E-35 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00097 Anthranilate synthase component II signature 127 139 7.4E-35 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00097 Anthranilate synthase component II signature 172 185 7.4E-35 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00097 Anthranilate synthase component II signature 11 25 7.4E-35 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 PRINTS PR00097 Anthranilate synthase component II signature 82 93 7.4E-35 T 12-10-2018 UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 Pfam PF00117 Glutamine amidotransferase class-I 13 193 5.3E-51 T 12-10-2018 IPR017926 Glutamine amidotransferase UA74_00115 a1956c73b7f240eaf0504f90f80794e3 221 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 11 193 8.6E-67 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_11905 dbfd22e8a35c44e92410230711d939bd 357 SUPERFAMILY SSF56112 5 322 2.62E-28 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_11905 dbfd22e8a35c44e92410230711d939bd 357 Gene3D G3DSA:3.30.200.20 14 109 4.8E-6 T 12-10-2018 UA74_11905 dbfd22e8a35c44e92410230711d939bd 357 Gene3D G3DSA:3.90.1200.10 125 337 1.0E-25 T 12-10-2018 UA74_11905 dbfd22e8a35c44e92410230711d939bd 357 Pfam PF01636 Phosphotransferase enzyme family 31 298 2.1E-22 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SUPERFAMILY SSF57884 6 83 2.35E-30 T 12-10-2018 IPR035451 Ada-like domain superfamily UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Pfam PF06029 AlkA N-terminal domain 211 334 2.0E-29 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Pfam PF12833 Helix-turn-helix domain 107 186 1.2E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SMART SM01009 210 334 3.3E-41 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:1.10.1670.10 464 520 2.4E-6 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SUPERFAMILY SSF55945 211 314 6.59E-18 T 12-10-2018 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SMART SM00342 101 184 9.0E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SMART SM00478 344 519 1.4E-4 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:3.40.10.10 6 74 6.4E-28 T 12-10-2018 IPR035451 Ada-like domain superfamily UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:1.10.340.30 336 460 6.8E-31 T 12-10-2018 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SUPERFAMILY SSF48150 325 516 1.41E-33 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:1.10.10.60 87 190 1.0E-14 T 12-10-2018 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Pfam PF02805 Metal binding domain of Ada 8 72 6.1E-29 T 12-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 SUPERFAMILY SSF46689 137 187 2.78E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_07775 a3ebab771f0f5fd75f5118e5cbc3f9ce 520 Gene3D G3DSA:3.30.310.20 210 334 2.1E-26 T 12-10-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily UA74_10790 4256b19f7b3451453c73ea0cc99c2d24 253 Gene3D G3DSA:3.40.50.300 1 204 8.0E-15 T 12-10-2018 UA74_10790 4256b19f7b3451453c73ea0cc99c2d24 253 SUPERFAMILY SSF52540 1 201 8.33E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10790 4256b19f7b3451453c73ea0cc99c2d24 253 Pfam PF02223 Thymidylate kinase 5 194 7.3E-5 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 UA74_28400 3ac63d149622236630ca05bebd8a600d 134 Gene3D G3DSA:2.40.50.100 65 127 1.1E-14 T 12-10-2018 UA74_28400 3ac63d149622236630ca05bebd8a600d 134 Gene3D G3DSA:1.10.1660.10 2 49 3.7E-7 T 12-10-2018 UA74_28400 3ac63d149622236630ca05bebd8a600d 134 SUPERFAMILY SSF50331 10 127 4.13E-16 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UA74_28400 3ac63d149622236630ca05bebd8a600d 134 Pfam PF03459 TOBE domain 66 125 2.2E-7 T 12-10-2018 IPR005116 Transport-associated OB, type 1 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 Gene3D G3DSA:3.40.50.1370 136 282 1.5E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 305 38.816 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 2.4E-17 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 2.4E-17 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 2.4E-17 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 2.4E-17 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 SUPERFAMILY SSF53671 1 304 1.3E-92 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 148 4.9E-40 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 301 3.4E-21 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 303 4.9E-87 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 3.2E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 3.2E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 3.2E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 3.2E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 3.2E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 3.2E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12190 4e0d2695454fdc7df320d36de05499ed 309 Gene3D G3DSA:3.40.50.1370 5 298 1.5E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UA74_12310 229b20cba7146c261b559068ca6006b5 443 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 11 407 55.494 T 12-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UA74_12310 229b20cba7146c261b559068ca6006b5 443 Gene3D G3DSA:3.90.870.10 7 216 5.1E-91 T 12-10-2018 UA74_12310 229b20cba7146c261b559068ca6006b5 443 Pfam PF00925 GTP cyclohydrolase II 218 384 1.6E-71 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UA74_12310 229b20cba7146c261b559068ca6006b5 443 SUPERFAMILY SSF55821 14 217 5.95E-82 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily UA74_12310 229b20cba7146c261b559068ca6006b5 443 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 218 408 2.0E-72 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UA74_12310 229b20cba7146c261b559068ca6006b5 443 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 10 214 38.239 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12310 229b20cba7146c261b559068ca6006b5 443 PIRSF PIRSF001259 10 414 1.2E-178 T 12-10-2018 UA74_12310 229b20cba7146c261b559068ca6006b5 443 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 215 411 40.561 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UA74_12310 229b20cba7146c261b559068ca6006b5 443 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 210 6.7E-74 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12310 229b20cba7146c261b559068ca6006b5 443 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 16 209 2.3E-86 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12310 229b20cba7146c261b559068ca6006b5 443 Gene3D G3DSA:3.40.50.10990 217 388 3.2E-74 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UA74_12310 229b20cba7146c261b559068ca6006b5 443 SUPERFAMILY SSF142695 216 387 5.1E-71 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UA74_05100 ffa1b0e6decd87a63a79f08c2ce49a6d 428 Gene3D G3DSA:1.10.260.40 15 75 3.2E-12 T 12-10-2018 UA74_05100 ffa1b0e6decd87a63a79f08c2ce49a6d 428 SUPERFAMILY SSF47413 15 69 5.07E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_05100 ffa1b0e6decd87a63a79f08c2ce49a6d 428 Pfam PF13560 Helix-turn-helix domain 15 72 1.3E-8 T 12-10-2018 UA74_05100 ffa1b0e6decd87a63a79f08c2ce49a6d 428 SMART SM00530 14 69 0.0011 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 SUPERFAMILY SSF53738 7 121 1.18E-31 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 SUPERFAMILY SSF53738 257 361 1.84E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 SUPERFAMILY SSF55957 365 448 5.62E-18 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 363 1.0E-25 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 Gene3D G3DSA:3.40.120.10 170 247 3.2E-31 T 12-10-2018 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 Gene3D G3DSA:3.40.120.10 5 137 2.4E-44 T 12-10-2018 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 370 447 9.4E-16 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 131 2.0E-29 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 Gene3D G3DSA:3.40.120.10 248 365 9.1E-35 T 12-10-2018 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 251 2.5E-24 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 231 246 6.4E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 202 215 6.4E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 168 187 6.4E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 6.4E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 SUPERFAMILY SSF53738 151 253 2.16E-28 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_26585 b531a9f090bc1c746d8f92ae47a1d7b9 449 Gene3D G3DSA:3.30.310.50 366 449 5.0E-21 T 12-10-2018 UA74_11235 320711b993c7463b3fa06c77a78abc89 295 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 10 234 5.0E-92 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c UA74_11235 320711b993c7463b3fa06c77a78abc89 295 SUPERFAMILY SSF51679 1 294 6.33E-54 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_11235 320711b993c7463b3fa06c77a78abc89 295 Pfam PF00296 Luciferase-like monooxygenase 1 235 1.2E-39 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_11235 320711b993c7463b3fa06c77a78abc89 295 Gene3D G3DSA:3.20.20.30 1 283 6.7E-64 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_10945 f4f643f7e8b97c8d9fa27dba6bdba043 135 Pfam PF07876 Stress responsive A/B Barrel Domain 2 89 5.5E-8 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel UA74_10945 f4f643f7e8b97c8d9fa27dba6bdba043 135 SMART SM00886 2 90 1.5E-4 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel UA74_10945 f4f643f7e8b97c8d9fa27dba6bdba043 135 Gene3D G3DSA:3.30.70.100 1 90 3.5E-6 T 12-10-2018 UA74_10945 f4f643f7e8b97c8d9fa27dba6bdba043 135 SUPERFAMILY SSF54909 1 95 1.25E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_26045 9f4f44a228201c3966d1e1808619d987 99 SUPERFAMILY SSF141000 3 94 1.14E-27 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 UA74_26045 9f4f44a228201c3966d1e1808619d987 99 Gene3D G3DSA:1.10.20.60 2 94 9.9E-22 T 12-10-2018 UA74_26045 9f4f44a228201c3966d1e1808619d987 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.608 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UA74_26045 9f4f44a228201c3966d1e1808619d987 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.4E-22 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UA74_26045 9f4f44a228201c3966d1e1808619d987 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.4E-15 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Pfam PF00009 Elongation factor Tu GTP binding domain 11 284 5.6E-68 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF50447 267 406 5.81E-33 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Pfam PF14492 Elongation Factor G, domain II 406 480 1.7E-34 T 12-10-2018 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF52540 8 284 4.71E-109 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_02930 dda7ef301807cd604661af03398c6c5e 699 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 2.5E-35 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site UA74_02930 dda7ef301807cd604661af03398c6c5e 699 SMART SM00838 605 692 8.4E-58 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like UA74_02930 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF54980 406 483 3.96E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:3.30.70.870 408 485 8.7E-32 T 12-10-2018 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF54211 481 604 8.09E-41 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:3.40.50.300 5 297 1.3E-113 T 12-10-2018 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Pfam PF03764 Elongation factor G, domain IV 481 603 1.0E-47 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:2.40.30.10 298 407 4.4E-40 T 12-10-2018 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:3.30.230.10 486 692 9.4E-89 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Hamap MF_00054_B Elongation factor G [fusA]. 8 696 110.018 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Pfam PF00679 Elongation factor G C-terminus 606 691 1.5E-30 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like UA74_02930 dda7ef301807cd604661af03398c6c5e 699 TIGRFAM TIGR00484 EF-G: translation elongation factor G 7 696 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Gene3D G3DSA:3.30.70.240 609 679 9.4E-89 T 12-10-2018 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 SUPERFAMILY SSF54980 608 694 1.97E-30 T 12-10-2018 IPR035647 EF-G domain III/V-like UA74_02930 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 80 90 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 60 68 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 96 107 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 PRINTS PR00315 GTP-binding elongation factor signature 132 141 7.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 SMART SM00889 482 603 8.9E-73 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 UA74_02930 dda7ef301807cd604661af03398c6c5e 699 Pfam PF03144 Elongation factor Tu domain 2 326 393 5.1E-13 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UA74_26920 b95330f818520eb1dcb17e4f1eb4c979 321 Gene3D G3DSA:1.10.10.10 1 85 1.5E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26920 b95330f818520eb1dcb17e4f1eb4c979 321 Gene3D G3DSA:3.40.190.10 170 270 8.9E-43 T 12-10-2018 UA74_26920 b95330f818520eb1dcb17e4f1eb4c979 321 SUPERFAMILY SSF53850 92 299 7.91E-33 T 12-10-2018 UA74_26920 b95330f818520eb1dcb17e4f1eb4c979 321 Gene3D G3DSA:3.40.190.10 93 279 8.9E-43 T 12-10-2018 UA74_26920 b95330f818520eb1dcb17e4f1eb4c979 321 Pfam PF03466 LysR substrate binding domain 90 294 3.6E-37 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_26920 b95330f818520eb1dcb17e4f1eb4c979 321 SUPERFAMILY SSF46785 2 109 4.48E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_26920 b95330f818520eb1dcb17e4f1eb4c979 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.7E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_03080 720b8a704051ed300d171cc1835a2579 90 SUPERFAMILY SSF55729 5 73 1.31E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_03080 720b8a704051ed300d171cc1835a2579 90 Pfam PF00583 Acetyltransferase (GNAT) family 4 50 4.3E-6 T 12-10-2018 IPR000182 GNAT domain UA74_03080 720b8a704051ed300d171cc1835a2579 90 Gene3D G3DSA:3.40.630.30 1 86 4.9E-19 T 12-10-2018 UA74_02535 8da6ab573b8411d577813e469943fb58 405 Gene3D G3DSA:3.40.50.80 161 297 4.8E-27 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_02535 8da6ab573b8411d577813e469943fb58 405 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 322 394 4.5E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 UA74_02535 8da6ab573b8411d577813e469943fb58 405 SUPERFAMILY SSF54292 285 402 6.55E-26 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 UA74_02535 8da6ab573b8411d577813e469943fb58 405 SUPERFAMILY SSF52343 147 292 4.45E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_02535 8da6ab573b8411d577813e469943fb58 405 Gene3D G3DSA:3.10.20.30 304 405 2.2E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily UA74_02535 8da6ab573b8411d577813e469943fb58 405 SUPERFAMILY SSF63380 25 156 1.59E-17 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_02535 8da6ab573b8411d577813e469943fb58 405 Pfam PF00175 Oxidoreductase NAD-binding domain 168 275 2.2E-14 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 UA74_02535 8da6ab573b8411d577813e469943fb58 405 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 352 360 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 Gene3D G3DSA:1.10.286.20 190 236 1.4E-37 T 12-10-2018 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 SUPERFAMILY SSF46934 3 56 2.66E-16 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 Gene3D G3DSA:3.30.479.20 160 270 1.4E-37 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 Gene3D G3DSA:1.10.8.10 1 56 1.4E-23 T 12-10-2018 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 271 2.0E-75 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 Hamap MF_00050 Elongation factor Ts [tsf]. 1 272 63.792 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 SUPERFAMILY SSF54713 58 270 9.45E-39 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 Pfam PF00889 Elongation factor TS 67 271 1.6E-61 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 Gene3D G3DSA:3.30.479.20 57 143 3.4E-18 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 UA74_08945 511886bc47f1a638a429de1d23390fcd 272 ProSitePatterns PS01127 Elongation factor Ts signature 2. 71 81 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UA74_03460 e741935038d4d0e77a0859822565c08d 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 60 87 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 UA74_03460 e741935038d4d0e77a0859822565c08d 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 32 282 6.6E-43 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm UA74_03460 e741935038d4d0e77a0859822565c08d 292 Gene3D G3DSA:1.10.8.100 226 290 3.5E-19 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 UA74_03460 e741935038d4d0e77a0859822565c08d 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 28 289 48.225 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 UA74_03460 e741935038d4d0e77a0859822565c08d 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 28 286 7.3E-75 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 UA74_03460 e741935038d4d0e77a0859822565c08d 292 Gene3D G3DSA:3.40.50.150 4 221 5.3E-59 T 12-10-2018 UA74_03460 e741935038d4d0e77a0859822565c08d 292 SMART SM00650 44 218 2.6E-65 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 UA74_03460 e741935038d4d0e77a0859822565c08d 292 SUPERFAMILY SSF53335 28 286 1.75E-63 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_29515 b21c9573869bf4699fc28092531c9e06 408 SUPERFAMILY SSF55874 292 402 2.26E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_29515 b21c9573869bf4699fc28092531c9e06 408 Pfam PF07730 Histidine kinase 198 263 3.2E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_29515 b21c9573869bf4699fc28092531c9e06 408 Gene3D G3DSA:3.30.565.10 272 403 4.0E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_07065 550942032342d6ea10fef9c30cd96666 476 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 347 356 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07065 550942032342d6ea10fef9c30cd96666 476 Gene3D G3DSA:2.40.10.170 9 88 1.9E-28 T 12-10-2018 UA74_07065 550942032342d6ea10fef9c30cd96666 476 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 15 86 5.2E-23 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07065 550942032342d6ea10fef9c30cd96666 476 Hamap MF_01347 ATP synthase subunit beta [atpB]. 10 474 54.284 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 UA74_07065 550942032342d6ea10fef9c30cd96666 476 Gene3D G3DSA:1.10.1140.10 359 476 3.6E-51 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07065 550942032342d6ea10fef9c30cd96666 476 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 143 356 2.3E-62 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07065 550942032342d6ea10fef9c30cd96666 476 SUPERFAMILY SSF47917 359 474 4.45E-48 T 12-10-2018 UA74_07065 550942032342d6ea10fef9c30cd96666 476 Gene3D G3DSA:3.40.50.300 89 358 1.7E-101 T 12-10-2018 UA74_07065 550942032342d6ea10fef9c30cd96666 476 SUPERFAMILY SSF50615 12 87 8.63E-24 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_07065 550942032342d6ea10fef9c30cd96666 476 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 12 472 1.2E-241 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 UA74_07065 550942032342d6ea10fef9c30cd96666 476 SUPERFAMILY SSF52540 90 361 2.31E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07065 550942032342d6ea10fef9c30cd96666 476 SMART SM00382 155 341 7.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 SMART SM00420 6 58 2.2E-15 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 SUPERFAMILY SSF100950 75 243 8.9E-27 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 SMART SM01134 72 242 5.1E-56 T 12-10-2018 UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.4E-15 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.6E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.6E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 Pfam PF00455 DeoR C terminal sensor domain 74 240 1.2E-43 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 SUPERFAMILY SSF46785 4 64 4.77E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_19815 9550a33ae18cebdb0f906a40c9a5448d 261 Gene3D G3DSA:3.40.50.1360 72 236 1.7E-6 T 12-10-2018 UA74_16935 5b010d2dc4253388801eb29262285d8e 355 Gene3D G3DSA:1.10.260.40 7 73 1.2E-17 T 12-10-2018 UA74_16935 5b010d2dc4253388801eb29262285d8e 355 Gene3D G3DSA:3.40.50.2300 103 336 1.2E-38 T 12-10-2018 UA74_16935 5b010d2dc4253388801eb29262285d8e 355 Gene3D G3DSA:3.40.50.2300 181 311 1.2E-38 T 12-10-2018 UA74_16935 5b010d2dc4253388801eb29262285d8e 355 SUPERFAMILY SSF53822 86 335 4.32E-27 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_16935 5b010d2dc4253388801eb29262285d8e 355 SMART SM00354 13 86 5.5E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_16935 5b010d2dc4253388801eb29262285d8e 355 Pfam PF00356 Bacterial regulatory proteins, lacI family 18 63 4.9E-11 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_16935 5b010d2dc4253388801eb29262285d8e 355 Pfam PF13377 Periplasmic binding protein-like domain 189 336 6.1E-21 T 12-10-2018 UA74_16935 5b010d2dc4253388801eb29262285d8e 355 SUPERFAMILY SSF47413 17 70 9.21E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_16575 b9c8ff0070c035d79a8bacd2cc68f717 507 Gene3D G3DSA:3.40.50.2300 221 369 1.0E-14 T 12-10-2018 UA74_16575 b9c8ff0070c035d79a8bacd2cc68f717 507 SUPERFAMILY SSF53822 123 476 2.94E-17 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_16575 b9c8ff0070c035d79a8bacd2cc68f717 507 Gene3D G3DSA:3.40.50.2300 140 460 1.0E-14 T 12-10-2018 UA74_06255 280d3c4ca20d06e686c11d262dd573d8 252 SUPERFAMILY SSF54211 2 183 8.1E-41 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_06255 280d3c4ca20d06e686c11d262dd573d8 252 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 238 4.8E-105 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 UA74_06255 280d3c4ca20d06e686c11d262dd573d8 252 Gene3D G3DSA:3.30.230.70 17 246 2.8E-57 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_06255 280d3c4ca20d06e686c11d262dd573d8 252 SUPERFAMILY SSF55666 156 242 3.93E-22 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_06255 280d3c4ca20d06e686c11d262dd573d8 252 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 12-10-2018 IPR018336 Ribonuclease PH, conserved site UA74_06255 280d3c4ca20d06e686c11d262dd573d8 252 Hamap MF_00564 Ribonuclease PH [rph]. 12 239 41.742 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 UA74_06255 280d3c4ca20d06e686c11d262dd573d8 252 Pfam PF01138 3' exoribonuclease family, domain 1 12 141 2.9E-20 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_06255 280d3c4ca20d06e686c11d262dd573d8 252 Pfam PF03725 3' exoribonuclease family, domain 2 160 225 4.1E-10 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UA74_01055 9b45820c7637a51a6ed2f7636efc0b05 331 SUPERFAMILY SSF52540 3 253 8.11E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01055 9b45820c7637a51a6ed2f7636efc0b05 331 SMART SM00382 33 231 2.0E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01055 9b45820c7637a51a6ed2f7636efc0b05 331 Gene3D G3DSA:3.40.50.300 1 330 5.6E-92 T 12-10-2018 UA74_01055 9b45820c7637a51a6ed2f7636efc0b05 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 317 8.8E-20 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_01055 9b45820c7637a51a6ed2f7636efc0b05 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 1.4E-15 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_01055 9b45820c7637a51a6ed2f7636efc0b05 331 Pfam PF00005 ABC transporter 25 182 1.4E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_21935 ef5c511dde760893d00eca64819e8cc6 488 SUPERFAMILY SSF51445 36 396 8.44E-22 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_21935 ef5c511dde760893d00eca64819e8cc6 488 Gene3D G3DSA:3.20.20.80 40 392 8.7E-30 T 12-10-2018 UA74_01000 c10bdc723975899ce0268130f2bbe77a 500 Gene3D G3DSA:3.40.50.300 255 494 3.1E-41 T 12-10-2018 UA74_01000 c10bdc723975899ce0268130f2bbe77a 500 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_01000 c10bdc723975899ce0268130f2bbe77a 500 SMART SM00382 279 472 9.8E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01000 c10bdc723975899ce0268130f2bbe77a 500 SMART SM00382 30 217 3.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01000 c10bdc723975899ce0268130f2bbe77a 500 Gene3D G3DSA:3.40.50.300 1 244 1.9E-56 T 12-10-2018 UA74_01000 c10bdc723975899ce0268130f2bbe77a 500 SUPERFAMILY SSF52540 262 478 3.61E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01000 c10bdc723975899ce0268130f2bbe77a 500 Pfam PF00005 ABC transporter 21 170 6.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_01000 c10bdc723975899ce0268130f2bbe77a 500 SUPERFAMILY SSF52540 4 222 2.76E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01000 c10bdc723975899ce0268130f2bbe77a 500 Pfam PF00005 ABC transporter 271 423 7.4E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_02260 ad7b93775238321221036bedb3b8ff29 283 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 102 7.6E-21 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UA74_02260 ad7b93775238321221036bedb3b8ff29 283 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 166 270 7.4E-37 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UA74_02260 ad7b93775238321221036bedb3b8ff29 283 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 270 4.7E-79 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UA74_02260 ad7b93775238321221036bedb3b8ff29 283 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 226 248 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UA74_02260 ad7b93775238321221036bedb3b8ff29 283 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 270 26.736 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UA74_02260 ad7b93775238321221036bedb3b8ff29 283 SUPERFAMILY SSF48179 165 272 2.55E-34 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_02260 ad7b93775238321221036bedb3b8ff29 283 PIRSF PIRSF000193 1 273 4.6E-69 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UA74_02260 ad7b93775238321221036bedb3b8ff29 283 Gene3D G3DSA:3.40.50.720 1 169 8.4E-44 T 12-10-2018 UA74_02260 ad7b93775238321221036bedb3b8ff29 283 SUPERFAMILY SSF51735 3 162 1.07E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_02260 ad7b93775238321221036bedb3b8ff29 283 Gene3D G3DSA:1.10.3730.10 170 272 5.0E-38 T 12-10-2018 UA74_24630 58f775d9e60f4e2038c0519610999d57 1795 Pfam PF00271 Helicase conserved C-terminal domain 550 615 1.7E-11 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_24630 58f775d9e60f4e2038c0519610999d57 1795 Gene3D G3DSA:3.40.50.300 59 275 2.5E-53 T 12-10-2018 UA74_24630 58f775d9e60f4e2038c0519610999d57 1795 SMART SM00487 71 286 5.1E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_24630 58f775d9e60f4e2038c0519610999d57 1795 SUPERFAMILY SSF52540 85 620 5.79E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24630 58f775d9e60f4e2038c0519610999d57 1795 SMART SM00490 531 615 1.5E-11 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_24630 58f775d9e60f4e2038c0519610999d57 1795 Pfam PF00270 DEAD/DEAH box helicase 76 261 1.3E-21 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_24630 58f775d9e60f4e2038c0519610999d57 1795 Pfam PF08494 DEAD/H associated 878 1071 5.4E-73 T 12-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 UA74_14435 bb271c40cb9af53fdba4387e998de4d5 342 Gene3D G3DSA:3.40.50.1980 181 341 6.4E-38 T 12-10-2018 UA74_14435 bb271c40cb9af53fdba4387e998de4d5 342 Pfam PF01497 Periplasmic binding protein 63 301 2.2E-19 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_14435 bb271c40cb9af53fdba4387e998de4d5 342 SUPERFAMILY SSF53807 46 330 4.71E-45 T 12-10-2018 UA74_14435 bb271c40cb9af53fdba4387e998de4d5 342 Gene3D G3DSA:3.40.50.1980 40 179 3.0E-38 T 12-10-2018 UA74_05350 5255f898cf35194983848c622fc9a363 468 SUPERFAMILY SSF49384 380 468 3.07E-15 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UA74_05350 5255f898cf35194983848c622fc9a363 468 Gene3D G3DSA:3.20.20.80 57 367 1.9E-121 T 12-10-2018 UA74_05350 5255f898cf35194983848c622fc9a363 468 SMART SM00637 382 465 2.3E-10 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_05350 5255f898cf35194983848c622fc9a363 468 Pfam PF00331 Glycosyl hydrolase family 10 62 356 1.5E-109 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UA74_05350 5255f898cf35194983848c622fc9a363 468 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 284 294 - T 12-10-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6717|MetaCyc: PWY-6784 UA74_05350 5255f898cf35194983848c622fc9a363 468 PRINTS PR00134 Glycosyl hydrolase family 10 signature 175 186 7.5E-17 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UA74_05350 5255f898cf35194983848c622fc9a363 468 PRINTS PR00134 Glycosyl hydrolase family 10 signature 220 231 7.5E-17 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UA74_05350 5255f898cf35194983848c622fc9a363 468 PRINTS PR00134 Glycosyl hydrolase family 10 signature 133 145 7.5E-17 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UA74_05350 5255f898cf35194983848c622fc9a363 468 PRINTS PR00134 Glycosyl hydrolase family 10 signature 250 262 7.5E-17 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UA74_05350 5255f898cf35194983848c622fc9a363 468 SUPERFAMILY SSF51445 59 360 2.63E-107 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_05350 5255f898cf35194983848c622fc9a363 468 Gene3D G3DSA:2.60.40.290 379 468 3.1E-20 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 UA74_05350 5255f898cf35194983848c622fc9a363 468 SMART SM00633 102 358 4.8E-131 T 12-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UA74_01845 70cd2b599bb006dc42c61f7a77e6d2d7 334 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 81 296 1.2E-32 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase UA74_01845 70cd2b599bb006dc42c61f7a77e6d2d7 334 SUPERFAMILY SSF51197 70 331 1.83E-56 T 12-10-2018 UA74_01845 70cd2b599bb006dc42c61f7a77e6d2d7 334 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 59 333 7.2E-129 T 12-10-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 UA74_01845 70cd2b599bb006dc42c61f7a77e6d2d7 334 Gene3D G3DSA:2.60.120.620 36 332 1.7E-101 T 12-10-2018 UA74_18690 3d8bb1776e12991d724c867444e84b21 426 Gene3D G3DSA:3.20.20.70 145 415 4.4E-36 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_18690 3d8bb1776e12991d724c867444e84b21 426 SMART SM01130 144 419 3.4E-8 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_18690 3d8bb1776e12991d724c867444e84b21 426 SUPERFAMILY SSF51569 152 409 1.05E-26 T 12-10-2018 UA74_18690 3d8bb1776e12991d724c867444e84b21 426 Pfam PF00701 Dihydrodipicolinate synthetase family 183 401 2.1E-8 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_02545 259792332f140200da4fb677c0f46043 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 197 218 8.6E-12 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_02545 259792332f140200da4fb677c0f46043 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 50 70 8.6E-12 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_02545 259792332f140200da4fb677c0f46043 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 151 174 8.6E-12 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_02545 259792332f140200da4fb677c0f46043 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 228 252 8.6E-12 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_02545 259792332f140200da4fb677c0f46043 286 PRINTS PR00377 Inositol monophosphatase superfamily signature 102 118 8.6E-12 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_02545 259792332f140200da4fb677c0f46043 286 SUPERFAMILY SSF56655 15 280 3.93E-35 T 12-10-2018 UA74_02545 259792332f140200da4fb677c0f46043 286 Gene3D G3DSA:3.40.190.80 166 284 1.1E-10 T 12-10-2018 UA74_02545 259792332f140200da4fb677c0f46043 286 Gene3D G3DSA:3.30.540.10 5 160 6.0E-22 T 12-10-2018 UA74_02545 259792332f140200da4fb677c0f46043 286 Pfam PF00459 Inositol monophosphatase family 21 253 3.1E-27 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_30280 3c91e2feb220ed9d16942642d7d6b45f 331 Pfam PF02195 ParB-like nuclease domain 68 157 4.2E-26 T 12-10-2018 IPR003115 ParB/Sulfiredoxin UA74_30280 3c91e2feb220ed9d16942642d7d6b45f 331 SUPERFAMILY SSF110849 63 160 2.88E-29 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily UA74_30280 3c91e2feb220ed9d16942642d7d6b45f 331 Gene3D G3DSA:1.10.10.2830 144 258 4.3E-34 T 12-10-2018 UA74_30280 3c91e2feb220ed9d16942642d7d6b45f 331 SMART SM00470 67 157 5.2E-35 T 12-10-2018 IPR003115 ParB/Sulfiredoxin UA74_30280 3c91e2feb220ed9d16942642d7d6b45f 331 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 65 242 5.8E-61 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 UA74_30280 3c91e2feb220ed9d16942642d7d6b45f 331 SUPERFAMILY SSF109709 149 258 5.49E-32 T 12-10-2018 UA74_30280 3c91e2feb220ed9d16942642d7d6b45f 331 Gene3D G3DSA:3.90.1530.30 80 142 3.5E-26 T 12-10-2018 UA74_11640 728baaf9187d357c1d918d817a5fa5f3 489 SUPERFAMILY SSF53720 11 487 7.33E-165 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_11640 728baaf9187d357c1d918d817a5fa5f3 489 Gene3D G3DSA:3.40.605.10 29 483 1.2E-171 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_11640 728baaf9187d357c1d918d817a5fa5f3 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UA74_11640 728baaf9187d357c1d918d817a5fa5f3 489 Pfam PF00171 Aldehyde dehydrogenase family 21 485 4.8E-164 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_11640 728baaf9187d357c1d918d817a5fa5f3 489 Gene3D G3DSA:3.40.309.10 261 454 1.2E-171 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_09405 8569f25117587b2199c0863a5e30ee99 477 SUPERFAMILY SSF63411 285 464 1.75E-39 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_09405 8569f25117587b2199c0863a5e30ee99 477 Pfam PF00675 Insulinase (Peptidase family M16) 59 206 1.3E-38 T 12-10-2018 IPR011765 Peptidase M16, N-terminal UA74_09405 8569f25117587b2199c0863a5e30ee99 477 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 80 103 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 UA74_09405 8569f25117587b2199c0863a5e30ee99 477 SUPERFAMILY SSF63411 49 257 4.89E-60 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_09405 8569f25117587b2199c0863a5e30ee99 477 Pfam PF05193 Peptidase M16 inactive domain 213 396 1.4E-40 T 12-10-2018 IPR007863 Peptidase M16, C-terminal UA74_09405 8569f25117587b2199c0863a5e30ee99 477 Gene3D G3DSA:3.30.830.10 280 467 2.5E-47 T 12-10-2018 UA74_09405 8569f25117587b2199c0863a5e30ee99 477 Gene3D G3DSA:3.30.830.10 48 260 4.0E-71 T 12-10-2018 UA74_05300 a1bd8245fed7fcaf25c17f9dfa43aa24 318 Gene3D G3DSA:3.40.50.1820 17 318 3.9E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05300 a1bd8245fed7fcaf25c17f9dfa43aa24 318 Pfam PF07859 alpha/beta hydrolase fold 89 294 3.7E-49 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 UA74_05300 a1bd8245fed7fcaf25c17f9dfa43aa24 318 SUPERFAMILY SSF53474 49 314 2.41E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_13560 5bd867542443048d0750400c3c65714c 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13560 5bd867542443048d0750400c3c65714c 232 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 203 3.9E-13 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_13560 5bd867542443048d0750400c3c65714c 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.0E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13560 5bd867542443048d0750400c3c65714c 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.0E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13560 5bd867542443048d0750400c3c65714c 232 PRINTS PR00400 Tetracycline repressor protein signature 26 49 5.4E-12 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_13560 5bd867542443048d0750400c3c65714c 232 PRINTS PR00400 Tetracycline repressor protein signature 187 201 5.4E-12 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_13560 5bd867542443048d0750400c3c65714c 232 PRINTS PR00400 Tetracycline repressor protein signature 78 97 5.4E-12 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_13560 5bd867542443048d0750400c3c65714c 232 Gene3D G3DSA:1.10.357.10 1 210 3.2E-60 T 12-10-2018 UA74_13560 5bd867542443048d0750400c3c65714c 232 SUPERFAMILY SSF48498 77 205 3.67E-27 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_13560 5bd867542443048d0750400c3c65714c 232 SUPERFAMILY SSF46689 1 68 3.69E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 SUPERFAMILY SSF56634 25 544 1.02E-210 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 Pfam PF00199 Catalase 38 424 2.6E-169 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 SMART SM01060 38 427 2.2E-255 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 51 74 2.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 356 382 2.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 115 133 2.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 324 351 2.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 136 153 2.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 PRINTS PR00067 Catalase signature 155 173 2.3E-69 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 Gene3D G3DSA:2.40.180.10 2 449 4.0E-198 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 SUPERFAMILY SSF52317 549 718 1.17E-16 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 369 377 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 PIRSF PIRSF038927 7 719 0.0 T 12-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 Gene3D G3DSA:3.40.50.880 544 720 1.4E-38 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 Pfam PF01965 DJ-1/PfpI family 552 666 6.3E-9 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 ProSitePatterns PS00438 Catalase proximal active site signature. 74 90 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 Gene3D G3DSA:1.20.1370.20 450 543 2.1E-31 T 12-10-2018 UA74_13155 e4b989c5d178b356c9147317355d0b4d 721 Pfam PF06628 Catalase-related immune-responsive 455 517 2.3E-21 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UA74_02510 92dafad319b6d7ada51d3862f9fe538f 252 SUPERFAMILY SSF56655 15 249 2.75E-31 T 12-10-2018 UA74_02510 92dafad319b6d7ada51d3862f9fe538f 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 90 106 3.5E-5 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_02510 92dafad319b6d7ada51d3862f9fe538f 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 48 68 3.5E-5 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_02510 92dafad319b6d7ada51d3862f9fe538f 252 Pfam PF00459 Inositol monophosphatase family 17 227 9.6E-20 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_02510 92dafad319b6d7ada51d3862f9fe538f 252 Gene3D G3DSA:3.30.540.10 11 145 2.6E-24 T 12-10-2018 UA74_25910 3f293d6f5c7703e487568ccc4f1fd2da 354 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 232 251 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 UA74_25910 3f293d6f5c7703e487568ccc4f1fd2da 354 SMART SM01329 2 334 8.9E-158 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_25910 3f293d6f5c7703e487568ccc4f1fd2da 354 SUPERFAMILY SSF53659 2 329 1.73E-106 T 12-10-2018 UA74_25910 3f293d6f5c7703e487568ccc4f1fd2da 354 Gene3D G3DSA:3.40.718.10 1 338 2.4E-126 T 12-10-2018 UA74_25910 3f293d6f5c7703e487568ccc4f1fd2da 354 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 317 2.0E-86 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_25910 3f293d6f5c7703e487568ccc4f1fd2da 354 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 1 338 56.913 T 12-10-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 UA74_02660 0e5f3f33f378626905b9418b8246281f 303 Gene3D G3DSA:3.75.10.10 45 300 2.5E-52 T 12-10-2018 UA74_02660 0e5f3f33f378626905b9418b8246281f 303 SUPERFAMILY SSF55909 34 302 9.23E-49 T 12-10-2018 UA74_06650 91921b0ce62953fe84af4fc3baf42626 394 SUPERFAMILY SSF141523 237 361 3.79E-27 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like UA74_06650 91921b0ce62953fe84af4fc3baf42626 394 Gene3D G3DSA:2.40.440.10 237 379 3.2E-92 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like UA74_06650 91921b0ce62953fe84af4fc3baf42626 394 Gene3D G3DSA:2.60.40.3780 38 135 4.3E-29 T 12-10-2018 UA74_06650 91921b0ce62953fe84af4fc3baf42626 394 Pfam PF03734 L,D-transpeptidase catalytic domain 246 361 6.9E-16 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UA74_06650 91921b0ce62953fe84af4fc3baf42626 394 Gene3D G3DSA:2.60.40.3710 145 391 3.2E-92 T 12-10-2018 UA74_11360 66947715f3e5adf9697ac6ac427f80d6 290 SUPERFAMILY SSF51679 4 285 1.35E-57 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_11360 66947715f3e5adf9697ac6ac427f80d6 290 Gene3D G3DSA:3.20.20.30 1 281 3.0E-61 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_11360 66947715f3e5adf9697ac6ac427f80d6 290 Pfam PF00296 Luciferase-like monooxygenase 20 245 9.2E-46 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_11360 66947715f3e5adf9697ac6ac427f80d6 290 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 10 232 1.3E-89 T 12-10-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c UA74_02945 634cfbb2e48a2da96948738786f499fc 216 SUPERFAMILY SSF50447 6 213 1.06E-81 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_02945 634cfbb2e48a2da96948738786f499fc 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 8 209 2.7E-88 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02945 634cfbb2e48a2da96948738786f499fc 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site UA74_02945 634cfbb2e48a2da96948738786f499fc 216 Gene3D G3DSA:2.40.30.10 127 215 1.0E-16 T 12-10-2018 UA74_02945 634cfbb2e48a2da96948738786f499fc 216 Pfam PF00297 Ribosomal protein L3 99 186 1.0E-17 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02945 634cfbb2e48a2da96948738786f499fc 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 6 212 39.579 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02945 634cfbb2e48a2da96948738786f499fc 216 Gene3D G3DSA:2.40.50.620 37 101 6.4E-18 T 12-10-2018 UA74_14230 3e6764387fb35f88da9dbe043add7566 255 SUPERFAMILY SSF55729 53 211 2.98E-12 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_14230 3e6764387fb35f88da9dbe043add7566 255 Pfam PF08445 FR47-like protein 160 212 6.8E-7 T 12-10-2018 IPR013653 FR47-like GO:0016747 UA74_14230 3e6764387fb35f88da9dbe043add7566 255 Gene3D G3DSA:3.40.630.30 27 220 6.3E-16 T 12-10-2018 UA74_25420 3d9853f2b4f0b45d7edc21e06d110545 328 Gene3D G3DSA:3.40.47.10 182 328 1.0E-41 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_25420 3d9853f2b4f0b45d7edc21e06d110545 328 Gene3D G3DSA:3.40.47.10 7 181 5.8E-61 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_25420 3d9853f2b4f0b45d7edc21e06d110545 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 15 327 58.231 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_25420 3d9853f2b4f0b45d7edc21e06d110545 328 SUPERFAMILY SSF53901 15 326 8.86E-60 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_25420 3d9853f2b4f0b45d7edc21e06d110545 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 235 325 3.3E-29 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_25420 3d9853f2b4f0b45d7edc21e06d110545 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 16 325 2.3E-97 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_25420 3d9853f2b4f0b45d7edc21e06d110545 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 120 196 4.6E-27 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_06280 3e1fef3adf673bc2cb11b53fcf12d1a5 215 SUPERFAMILY SSF53335 4 213 6.48E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_06280 3e1fef3adf673bc2cb11b53fcf12d1a5 215 Gene3D G3DSA:3.40.50.150 2 212 1.6E-77 T 12-10-2018 UA74_06280 3e1fef3adf673bc2cb11b53fcf12d1a5 215 Pfam PF13649 Methyltransferase domain 14 107 8.9E-11 T 12-10-2018 UA74_06280 3e1fef3adf673bc2cb11b53fcf12d1a5 215 Gene3D G3DSA:2.20.25.570 115 173 1.6E-77 T 12-10-2018 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 549 582 3.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 886 919 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 629 662 0.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 806 839 140.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 709 742 1.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 669 702 9.9 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 589 622 1.9 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 846 879 0.13 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SMART SM00028 509 542 15.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 Gene3D G3DSA:1.25.40.10 465 559 3.5E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF00931 NB-ARC domain 88 294 6.2E-9 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 Gene3D G3DSA:1.25.40.10 560 768 3.7E-56 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF48452 663 766 4.81E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF13374 Tetratricopeptide repeat 591 622 1.9E-4 T 12-10-2018 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF48452 552 690 5.12E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 Gene3D G3DSA:1.25.40.10 787 938 4.2E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 PRINTS PR00364 Disease resistance protein signature 89 104 3.8E-8 T 12-10-2018 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 PRINTS PR00364 Disease resistance protein signature 174 188 3.8E-8 T 12-10-2018 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 PRINTS PR00364 Disease resistance protein signature 264 278 3.8E-8 T 12-10-2018 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF48452 806 916 3.8E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF52540 58 325 1.72E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF13424 Tetratricopeptide repeat 710 766 5.0E-9 T 12-10-2018 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF13424 Tetratricopeptide repeat 629 692 4.9E-11 T 12-10-2018 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 Pfam PF13424 Tetratricopeptide repeat 510 581 1.2E-11 T 12-10-2018 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 SUPERFAMILY SSF48452 473 581 6.96E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03175 6db9c6f679a2c47cbcf6233f583294d4 942 Gene3D G3DSA:3.40.50.300 51 221 1.4E-22 T 12-10-2018 UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 SMART SM00345 16 75 1.2E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 Gene3D G3DSA:1.10.357.10 155 306 3.1E-33 T 12-10-2018 UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 157 303 1.4E-15 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 SUPERFAMILY SSF48498 163 306 1.11E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 PRINTS PR00400 Tetracycline repressor protein signature 113 136 1.1E-6 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 PRINTS PR00400 Tetracycline repressor protein signature 287 301 1.1E-6 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 Gene3D G3DSA:1.10.10.60 92 154 1.1E-25 T 12-10-2018 UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 SUPERFAMILY SSF46785 8 88 1.77E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 4.5E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 Gene3D G3DSA:1.10.10.10 12 87 1.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 Pfam PF00440 Bacterial regulatory proteins, tetR family 101 145 6.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_18540 80c7e02339d40f40492b4e8d9a4e71fd 307 SUPERFAMILY SSF46689 89 154 5.99E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_25030 36a09c4673cac75e87e98a66e3c213b2 366 Gene3D G3DSA:1.10.1610.10 25 352 4.6E-126 T 12-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 UA74_25030 36a09c4673cac75e87e98a66e3c213b2 366 Pfam PF02277 Phosphoribosyltransferase 25 360 8.6E-137 T 12-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 UA74_25030 36a09c4673cac75e87e98a66e3c213b2 366 SUPERFAMILY SSF52733 21 361 8.24E-113 T 12-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 UA74_25030 36a09c4673cac75e87e98a66e3c213b2 366 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 29 360 4.8E-128 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 UA74_25030 36a09c4673cac75e87e98a66e3c213b2 366 Gene3D G3DSA:3.40.50.10210 72 343 4.6E-126 T 12-10-2018 UA74_25030 36a09c4673cac75e87e98a66e3c213b2 366 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 27 362 36.88 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 UA74_28720 659ccbd3644501b078c3a22a50abade6 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 152 2.0E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_28720 659ccbd3644501b078c3a22a50abade6 165 Gene3D G3DSA:1.10.1740.10 1 92 4.9E-16 T 12-10-2018 UA74_28720 659ccbd3644501b078c3a22a50abade6 165 SUPERFAMILY SSF88946 4 82 8.63E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_28720 659ccbd3644501b078c3a22a50abade6 165 Gene3D G3DSA:1.10.10.10 97 155 3.6E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28720 659ccbd3644501b078c3a22a50abade6 165 SUPERFAMILY SSF88659 96 153 2.8E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_28720 659ccbd3644501b078c3a22a50abade6 165 Pfam PF04542 Sigma-70 region 2 8 73 1.6E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_28720 659ccbd3644501b078c3a22a50abade6 165 Pfam PF08281 Sigma-70, region 4 99 140 4.8E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_12460 79b15da29a9827a5b75f9bdebb1cf2f4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 157 181 7.0E-8 T 12-10-2018 UA74_12460 79b15da29a9827a5b75f9bdebb1cf2f4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 127 147 7.0E-8 T 12-10-2018 UA74_12460 79b15da29a9827a5b75f9bdebb1cf2f4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 36 60 7.0E-8 T 12-10-2018 UA74_12460 79b15da29a9827a5b75f9bdebb1cf2f4 495 Pfam PF07690 Major Facilitator Superfamily 38 438 8.3E-45 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_12460 79b15da29a9827a5b75f9bdebb1cf2f4 495 Gene3D G3DSA:1.20.1720.10 33 244 3.5E-46 T 12-10-2018 UA74_12460 79b15da29a9827a5b75f9bdebb1cf2f4 495 SUPERFAMILY SSF103473 28 489 7.72E-61 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_12460 79b15da29a9827a5b75f9bdebb1cf2f4 495 Gene3D G3DSA:1.20.1250.20 292 492 7.0E-13 T 12-10-2018 UA74_23870 bd0dfc8e9f3233e7db1fa19a945fe920 695 Gene3D G3DSA:3.40.50.880 397 623 3.4E-67 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_23870 bd0dfc8e9f3233e7db1fa19a945fe920 695 SUPERFAMILY SSF51445 17 371 9.78E-114 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_23870 bd0dfc8e9f3233e7db1fa19a945fe920 695 Gene3D G3DSA:3.20.20.80 10 393 1.1E-133 T 12-10-2018 UA74_23870 bd0dfc8e9f3233e7db1fa19a945fe920 695 Pfam PF02449 Beta-galactosidase 20 389 5.8E-146 T 12-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_23870 bd0dfc8e9f3233e7db1fa19a945fe920 695 Pfam PF08533 Beta-galactosidase C-terminal domain 629 690 1.5E-4 T 12-10-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_23870 bd0dfc8e9f3233e7db1fa19a945fe920 695 Gene3D G3DSA:2.60.40.1180 627 692 6.0E-11 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_23870 bd0dfc8e9f3233e7db1fa19a945fe920 695 PIRSF PIRSF001084 8 693 4.3E-249 T 12-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_23870 bd0dfc8e9f3233e7db1fa19a945fe920 695 Pfam PF08532 Beta-galactosidase trimerisation domain 400 619 1.8E-57 T 12-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_23870 bd0dfc8e9f3233e7db1fa19a945fe920 695 SUPERFAMILY SSF52317 397 620 2.9E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_06250 4a6261a6e161030c8a6084c480f34605 320 Pfam PF01544 CorA-like Mg2+ transporter protein 33 316 4.4E-60 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 UA74_06250 4a6261a6e161030c8a6084c480f34605 320 Gene3D G3DSA:1.20.58.340 130 243 3.2E-33 T 12-10-2018 UA74_06250 4a6261a6e161030c8a6084c480f34605 320 Gene3D G3DSA:3.30.460.20 6 129 8.2E-23 T 12-10-2018 UA74_06250 4a6261a6e161030c8a6084c480f34605 320 Gene3D G3DSA:1.20.58.340 244 320 2.3E-12 T 12-10-2018 UA74_06250 4a6261a6e161030c8a6084c480f34605 320 SUPERFAMILY SSF143865 5 255 4.45E-62 T 12-10-2018 UA74_06250 4a6261a6e161030c8a6084c480f34605 320 SUPERFAMILY SSF144083 256 317 1.57E-11 T 12-10-2018 UA74_28235 6fc06a32468a7f4952d416abbb2ac62a 347 Gene3D G3DSA:3.40.1190.20 1 341 2.5E-72 T 12-10-2018 IPR029056 Ribokinase-like UA74_28235 6fc06a32468a7f4952d416abbb2ac62a 347 SUPERFAMILY SSF53613 2 337 8.57E-58 T 12-10-2018 IPR029056 Ribokinase-like UA74_28235 6fc06a32468a7f4952d416abbb2ac62a 347 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 278 291 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_28235 6fc06a32468a7f4952d416abbb2ac62a 347 Pfam PF00294 pfkB family carbohydrate kinase 2 336 5.4E-43 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_13085 57184ad8c7dc875824beb8ffd7e41c6f 427 Gene3D G3DSA:3.40.50.2000 249 410 3.0E-43 T 12-10-2018 UA74_13085 57184ad8c7dc875824beb8ffd7e41c6f 427 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 223 404 2.0E-11 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 UA74_13085 57184ad8c7dc875824beb8ffd7e41c6f 427 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 9 408 1.7E-35 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 UA74_13085 57184ad8c7dc875824beb8ffd7e41c6f 427 SUPERFAMILY SSF53756 1 423 4.0E-69 T 12-10-2018 UA74_13085 57184ad8c7dc875824beb8ffd7e41c6f 427 Gene3D G3DSA:3.40.50.2000 1 248 1.9E-32 T 12-10-2018 UA74_17140 1fc173a43479ae261412f92b83229e40 334 PIRSF PIRSF001439 5 327 6.2E-63 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 UA74_17140 1fc173a43479ae261412f92b83229e40 334 Gene3D G3DSA:3.40.50.720 135 300 7.7E-80 T 12-10-2018 UA74_17140 1fc173a43479ae261412f92b83229e40 334 Gene3D G3DSA:3.30.1780.10 21 320 7.7E-80 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 UA74_17140 1fc173a43479ae261412f92b83229e40 334 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 5 327 6.0E-112 T 12-10-2018 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB UA74_17140 1fc173a43479ae261412f92b83229e40 334 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 22 225 3.4E-30 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 UA74_17140 1fc173a43479ae261412f92b83229e40 334 SUPERFAMILY SSF51735 9 326 3.77E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12130 53717f27064d0ed50377091e676e93dd 188 Pfam PF01202 Shikimate kinase 13 168 7.6E-42 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UA74_12130 53717f27064d0ed50377091e676e93dd 188 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UA74_12130 53717f27064d0ed50377091e676e93dd 188 SUPERFAMILY SSF52540 7 168 1.78E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12130 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 31 44 1.8E-17 T 12-10-2018 UA74_12130 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 59 67 1.8E-17 T 12-10-2018 UA74_12130 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 7 22 1.8E-17 T 12-10-2018 UA74_12130 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 97 114 1.8E-17 T 12-10-2018 UA74_12130 53717f27064d0ed50377091e676e93dd 188 PRINTS PR01100 Shikimate kinase family signature 77 86 1.8E-17 T 12-10-2018 UA74_12130 53717f27064d0ed50377091e676e93dd 188 Gene3D G3DSA:3.40.50.300 4 179 1.5E-52 T 12-10-2018 UA74_12130 53717f27064d0ed50377091e676e93dd 188 Hamap MF_00109 Shikimate kinase [aroK]. 4 169 27.001 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UA74_06070 8e1aa0df5fec6d44fe2ab65bd1bf2f37 386 SUPERFAMILY SSF55874 285 380 4.67E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_06070 8e1aa0df5fec6d44fe2ab65bd1bf2f37 386 Gene3D G3DSA:3.30.565.10 251 380 3.5E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_06070 8e1aa0df5fec6d44fe2ab65bd1bf2f37 386 Pfam PF07730 Histidine kinase 177 242 4.2E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_04730 c4b3f56e13016dd596d7ff8c05a3870e 379 SUPERFAMILY SSF55486 191 339 9.05E-14 T 12-10-2018 UA74_04730 c4b3f56e13016dd596d7ff8c05a3870e 379 Pfam PF11350 Protein of unknown function (DUF3152) 165 374 5.1E-59 T 12-10-2018 IPR022603 Domain of unknown function DUF3152 UA74_29095 6b83218ec99c9ed563f7835e06f7e450 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_29095 6b83218ec99c9ed563f7835e06f7e450 258 Pfam PF00005 ABC transporter 21 176 1.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_29095 6b83218ec99c9ed563f7835e06f7e450 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 5.3E-115 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 UA74_29095 6b83218ec99c9ed563f7835e06f7e450 258 SUPERFAMILY SSF52540 5 244 4.73E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29095 6b83218ec99c9ed563f7835e06f7e450 258 Gene3D G3DSA:3.40.50.300 2 256 5.0E-63 T 12-10-2018 UA74_29095 6b83218ec99c9ed563f7835e06f7e450 258 SMART SM00382 29 223 7.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_17145 72e75b7bc5c4e37983583b6e4ae8169f 331 SUPERFAMILY SSF53686 21 312 1.44E-69 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_17145 72e75b7bc5c4e37983583b6e4ae8169f 331 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 8 307 1.8E-114 T 12-10-2018 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA UA74_17145 72e75b7bc5c4e37983583b6e4ae8169f 331 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 291 1.2E-53 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_17145 72e75b7bc5c4e37983583b6e4ae8169f 331 Gene3D G3DSA:3.40.50.1100 25 298 5.3E-82 T 12-10-2018 UA74_17145 72e75b7bc5c4e37983583b6e4ae8169f 331 Gene3D G3DSA:3.40.50.1100 42 147 5.3E-82 T 12-10-2018 UA74_16760 c61cf54f13a1b3c6362006f28bb147d7 150 SUPERFAMILY SSF82607 22 105 2.22E-6 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_16760 c61cf54f13a1b3c6362006f28bb147d7 150 Pfam PF02575 YbaB/EbfC DNA-binding family 23 104 2.9E-6 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_05490 dd5352feb2e12bd03ac3793e4dc0d8ee 582 SUPERFAMILY SSF140453 83 163 7.32E-8 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_05490 dd5352feb2e12bd03ac3793e4dc0d8ee 582 Gene3D G3DSA:1.10.287.1060 78 169 1.3E-6 T 12-10-2018 UA74_19595 b50ac5c7c485bfbd2f4e70bd448ff170 413 SUPERFAMILY SSF50969 60 350 4.79E-6 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like UA74_19595 b50ac5c7c485bfbd2f4e70bd448ff170 413 Gene3D G3DSA:2.130.10.10 144 413 5.9E-7 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_08075 19f9286f154bc904027c588a0634266a 208 Pfam PF00574 Clp protease 27 201 7.8E-74 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA UA74_08075 19f9286f154bc904027c588a0634266a 208 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 38.533 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08075 19f9286f154bc904027c588a0634266a 208 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 12-10-2018 IPR018215 ClpP, Ser active site UA74_08075 19f9286f154bc904027c588a0634266a 208 SUPERFAMILY SSF52096 20 204 2.31E-62 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_08075 19f9286f154bc904027c588a0634266a 208 Gene3D G3DSA:3.90.226.10 1 207 7.9E-78 T 12-10-2018 UA74_08075 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08075 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08075 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08075 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08075 19f9286f154bc904027c588a0634266a 208 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 5.4E-40 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08075 19f9286f154bc904027c588a0634266a 208 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 12-10-2018 IPR033135 ClpP, histidine active site UA74_25100 d5b2069760a953a4d320e37a239124ad 242 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 28 227 8.0E-68 T 12-10-2018 UA74_25100 d5b2069760a953a4d320e37a239124ad 242 Pfam PF13829 Domain of unknown function (DUF4191) 19 234 1.6E-85 T 12-10-2018 IPR025445 Protein of unknown function DUF4191 UA74_15085 e54cf7f27f657848e5d2945fbb775fcb 211 Pfam PF13302 Acetyltransferase (GNAT) domain 13 146 9.7E-12 T 12-10-2018 IPR000182 GNAT domain UA74_15085 e54cf7f27f657848e5d2945fbb775fcb 211 SUPERFAMILY SSF55729 8 170 5.01E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_15085 e54cf7f27f657848e5d2945fbb775fcb 211 Gene3D G3DSA:3.40.630.30 3 201 2.5E-22 T 12-10-2018 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 SUPERFAMILY SSF53784 1 333 1.83E-117 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PIRSF PIRSF000532 1 338 2.1E-119 T 12-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 12-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 Pfam PF00365 Phosphofructokinase 2 296 4.0E-102 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 Gene3D G3DSA:3.40.50.460 140 277 1.1E-110 T 12-10-2018 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 321 2.4E-151 T 12-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 Gene3D G3DSA:3.40.50.450 3 322 1.1E-110 T 12-10-2018 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 43.9 T 12-10-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 4.0E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 4.0E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 4.0E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 4.0E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 4.0E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 4.0E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 4.0E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 4.0E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_24815 6be2a5ce58d29be5a83f7728788939ef 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 4.0E-72 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 PRINTS PR00733 Glycosyl hydrolase family 6 signature 141 160 3.1E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 PRINTS PR00733 Glycosyl hydrolase family 6 signature 330 343 3.1E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 PRINTS PR00733 Glycosyl hydrolase family 6 signature 344 364 3.1E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 PRINTS PR00733 Glycosyl hydrolase family 6 signature 180 193 3.1E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 PRINTS PR00733 Glycosyl hydrolase family 6 signature 265 278 3.1E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 PRINTS PR00733 Glycosyl hydrolase family 6 signature 295 305 3.1E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 PRINTS PR00733 Glycosyl hydrolase family 6 signature 368 382 3.1E-29 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 Pfam PF01341 Glycosyl hydrolases family 6 147 386 5.2E-63 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 PIRSF PIRSF001100 66 406 2.5E-77 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 185 201 - T 12-10-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 Gene3D G3DSA:3.20.20.40 120 406 8.2E-87 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 UA74_28775 d94b3ca39daa59e27d22cab667ffbb35 407 SUPERFAMILY SSF51989 122 404 6.54E-72 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 UA74_02145 ee98cd54cb9e85b7b987189b9f1cf561 186 Gene3D G3DSA:3.90.960.10 30 179 3.9E-21 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UA74_02145 ee98cd54cb9e85b7b987189b9f1cf561 186 Pfam PF04073 Aminoacyl-tRNA editing domain 48 167 8.5E-15 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_02145 ee98cd54cb9e85b7b987189b9f1cf561 186 SUPERFAMILY SSF55826 41 178 3.92E-20 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UA74_20720 3e5b86ee1c4f211ae49d3fb5aaee9d54 505 Pfam PF00005 ABC transporter 281 431 2.4E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_20720 3e5b86ee1c4f211ae49d3fb5aaee9d54 505 Gene3D G3DSA:3.40.50.300 269 500 5.6E-43 T 12-10-2018 UA74_20720 3e5b86ee1c4f211ae49d3fb5aaee9d54 505 Pfam PF00005 ABC transporter 24 181 9.3E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_20720 3e5b86ee1c4f211ae49d3fb5aaee9d54 505 SMART SM00382 290 480 4.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20720 3e5b86ee1c4f211ae49d3fb5aaee9d54 505 SMART SM00382 33 229 3.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20720 3e5b86ee1c4f211ae49d3fb5aaee9d54 505 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_20720 3e5b86ee1c4f211ae49d3fb5aaee9d54 505 SUPERFAMILY SSF52540 8 242 8.61E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20720 3e5b86ee1c4f211ae49d3fb5aaee9d54 505 Gene3D G3DSA:3.40.50.300 5 250 1.3E-55 T 12-10-2018 UA74_20720 3e5b86ee1c4f211ae49d3fb5aaee9d54 505 SUPERFAMILY SSF52540 277 486 1.5E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04655 c81b6095a9bbd572a6232b01a985a84a 359 PIRSF PIRSF012608 1 359 3.9E-73 T 12-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 UA74_04655 c81b6095a9bbd572a6232b01a985a84a 359 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 4 357 6.4E-93 T 12-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 UA74_28825 93f05aea3ff942c283ea319fe9695160 219 Gene3D G3DSA:3.40.50.10320 3 214 8.8E-23 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_28825 93f05aea3ff942c283ea319fe9695160 219 Pfam PF02585 GlcNAc-PI de-N-acetylase 14 126 4.9E-11 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_28825 93f05aea3ff942c283ea319fe9695160 219 SUPERFAMILY SSF102588 12 211 5.49E-28 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_13595 f19ebf3eea503b038818f4fc7642f7ac 388 SUPERFAMILY SSF100950 37 381 1.59E-74 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_13595 f19ebf3eea503b038818f4fc7642f7ac 388 Gene3D G3DSA:1.20.120.420 67 181 5.1E-70 T 12-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 UA74_13595 f19ebf3eea503b038818f4fc7642f7ac 388 Gene3D G3DSA:3.40.50.10470 182 373 5.1E-70 T 12-10-2018 UA74_13595 f19ebf3eea503b038818f4fc7642f7ac 388 Pfam PF01008 Initiation factor 2 subunit family 94 373 2.6E-46 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 179 194 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 SUPERFAMILY SSF140490 338 431 2.22E-34 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 SUPERFAMILY SSF142984 253 335 3.66E-22 T 12-10-2018 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 Gene3D G3DSA:3.40.50.11540 65 243 4.7E-79 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 Gene3D G3DSA:3.10.20.600 244 337 5.3E-29 T 12-10-2018 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 21 423 2.0E-186 T 12-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 60 231 2.0E-46 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 Pfam PF10531 SLBB domain 256 302 2.5E-10 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 SUPERFAMILY SSF142019 17 251 6.02E-87 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 Gene3D G3DSA:1.20.1440.230 339 437 1.3E-32 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 SMART SM00928 340 385 4.0E-24 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 344 423 1.0E-31 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02585 9072effc459179bf43c0d8dce6f3c4bd 446 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 353 364 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM00823 Phosphopantetheine attachment site 1328 1400 4.0E-32 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 407 521 1.8E-13 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF51735 1060 1271 8.11E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:3.40.366.10 539 811 7.3E-118 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF52151 538 801 1.8E-61 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 281 5.3E-86 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 289 404 1.1E-45 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM01294 1329 1396 1.6E-6 T 12-10-2018 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF08659 KR domain 1063 1236 4.2E-54 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:3.30.70.3290 477 851 7.3E-118 T 12-10-2018 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 194 210 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM00825 Beta-ketoacyl synthase 37 457 2.0E-209 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF53901 32 401 2.96E-103 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 541 808 3.0E-82 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:3.40.47.10 27 475 5.1E-181 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:3.40.50.720 852 1308 4.4E-146 T 12-10-2018 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1355 1370 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF00550 Phosphopantetheine attachment site 1331 1396 1.3E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF51735 869 1052 8.06E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1063 1238 6.2E-45 T 12-10-2018 UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF55048 660 718 2.75E-6 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Gene3D G3DSA:1.10.1200.10 1313 1403 7.1E-34 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 Pfam PF00698 Acyl transferase domain 541 779 1.5E-40 T 12-10-2018 IPR014043 Acyl transferase UA74_17310 cdbe32eb8e06f42c438dc6718e214301 1473 SUPERFAMILY SSF47336 1319 1406 7.07E-24 T 12-10-2018 IPR036736 ACP-like superfamily UA74_09360 5bc02bf3e09e54574adf22adce43e4b6 376 SMART SM00862 301 371 2.8E-11 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_09360 5bc02bf3e09e54574adf22adce43e4b6 376 Pfam PF02602 Uroporphyrinogen-III synthase HemD 29 270 2.9E-41 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_09360 5bc02bf3e09e54574adf22adce43e4b6 376 Gene3D G3DSA:3.40.50.10090 22 269 4.6E-65 T 12-10-2018 UA74_09360 5bc02bf3e09e54574adf22adce43e4b6 376 Gene3D G3DSA:1.10.10.10 284 374 4.5E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_09360 5bc02bf3e09e54574adf22adce43e4b6 376 SUPERFAMILY SSF46894 284 373 2.75E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_09360 5bc02bf3e09e54574adf22adce43e4b6 376 Gene3D G3DSA:3.40.50.10090 48 184 4.6E-65 T 12-10-2018 UA74_09360 5bc02bf3e09e54574adf22adce43e4b6 376 SUPERFAMILY SSF69618 17 274 4.58E-55 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_09360 5bc02bf3e09e54574adf22adce43e4b6 376 Pfam PF00486 Transcriptional regulatory protein, C terminal 312 371 1.4E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_29305 d38d2dba11ed3f75da255bc5303c81c3 449 Gene3D G3DSA:1.20.1250.20 2 402 1.5E-35 T 12-10-2018 UA74_29305 d38d2dba11ed3f75da255bc5303c81c3 449 ProSitePatterns PS00217 Sugar transport proteins signature 2. 321 346 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_29305 d38d2dba11ed3f75da255bc5303c81c3 449 ProSitePatterns PS00216 Sugar transport proteins signature 1. 58 74 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_29305 d38d2dba11ed3f75da255bc5303c81c3 449 Pfam PF07690 Major Facilitator Superfamily 13 246 1.8E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_29305 d38d2dba11ed3f75da255bc5303c81c3 449 Pfam PF07690 Major Facilitator Superfamily 248 399 2.7E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_29305 d38d2dba11ed3f75da255bc5303c81c3 449 SUPERFAMILY SSF103473 2 399 9.02E-41 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_23675 7ca5f357e94cb31fc8b7ea142042118a 522 SUPERFAMILY SSF53474 116 493 1.15E-14 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23675 7ca5f357e94cb31fc8b7ea142042118a 522 Pfam PF08386 TAP-like protein 421 520 1.1E-19 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal UA74_23675 7ca5f357e94cb31fc8b7ea142042118a 522 Pfam PF00561 alpha/beta hydrolase fold 141 343 1.0E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_24555 f3c6a2cc2478ed349b551247010a27c4 328 Pfam PF00005 ABC transporter 38 159 1.1E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_24555 f3c6a2cc2478ed349b551247010a27c4 328 SUPERFAMILY SSF52540 36 301 1.82E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24555 f3c6a2cc2478ed349b551247010a27c4 328 SMART SM00382 47 296 2.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_24555 f3c6a2cc2478ed349b551247010a27c4 328 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_07595 2e214c302fc08b09b8185aefc8038a11 756 SUPERFAMILY SSF81296 76 204 1.36E-18 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_07595 2e214c302fc08b09b8185aefc8038a11 756 Gene3D G3DSA:2.60.40.10 64 194 1.8E-27 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_07595 2e214c302fc08b09b8185aefc8038a11 756 Pfam PF00128 Alpha amylase, catalytic domain 234 335 7.1E-11 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07595 2e214c302fc08b09b8185aefc8038a11 756 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 80 170 1.3E-4 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_07595 2e214c302fc08b09b8185aefc8038a11 756 SUPERFAMILY SSF51011 648 749 2.01E-16 T 12-10-2018 UA74_07595 2e214c302fc08b09b8185aefc8038a11 756 Gene3D G3DSA:3.20.20.80 195 639 1.2E-188 T 12-10-2018 UA74_07595 2e214c302fc08b09b8185aefc8038a11 756 SMART SM00642 216 626 7.3E-10 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07595 2e214c302fc08b09b8185aefc8038a11 756 SUPERFAMILY SSF51445 195 634 2.22E-130 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07595 2e214c302fc08b09b8185aefc8038a11 756 Gene3D G3DSA:2.60.40.1180 647 749 1.9E-15 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_08205 df6e3776672a19c804142f73bbd39b74 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 22.894 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08205 df6e3776672a19c804142f73bbd39b74 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 1.1E-34 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08205 df6e3776672a19c804142f73bbd39b74 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08205 df6e3776672a19c804142f73bbd39b74 103 SUPERFAMILY SSF141091 1 100 1.96E-32 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08205 df6e3776672a19c804142f73bbd39b74 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 7.3E-26 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02745 f99f7da0e6df9416d0c046ddea12f5fe 291 Pfam PF01435 Peptidase family M48 68 284 5.7E-37 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 UA74_02745 f99f7da0e6df9416d0c046ddea12f5fe 291 Gene3D G3DSA:3.30.2010.10 61 151 3.6E-28 T 12-10-2018 UA74_02745 f99f7da0e6df9416d0c046ddea12f5fe 291 Hamap MF_00188 Protease HtpX [htpX]. 7 284 27.354 T 12-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 UA74_26075 bdad4423d81bfe3f3464b7d53113d4b4 68 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 3 40 8.4E-14 T 12-10-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 31 941 0.0 T 12-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 205 218 1.8E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 145 158 1.8E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 219 234 1.8E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 472 483 1.8E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 295 308 1.8E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 169 177 1.8E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 374 388 1.8E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 281 294 1.8E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 PRINTS PR00415 Aconitase family signature 534 547 1.8E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 ProSitePatterns PS01244 Aconitase family signature 2. 534 547 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 Gene3D G3DSA:1.10.1440.20 632 692 1.1E-19 T 12-10-2018 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 Pfam PF00694 Aconitase C-terminal domain 733 866 2.4E-41 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 ProSitePatterns PS00450 Aconitase family signature 1. 468 484 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 SUPERFAMILY SSF52016 672 941 2.75E-82 T 12-10-2018 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 Pfam PF00330 Aconitase family (aconitate hydratase) 75 603 5.0E-176 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 Gene3D G3DSA:3.30.499.20 12 374 1.4E-154 T 12-10-2018 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 Gene3D G3DSA:3.20.19.10 694 942 3.5E-101 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 UA74_11475 c4b6bb3d45425049225fb8f5ebd7955e 943 SUPERFAMILY SSF53732 8 668 6.8E-218 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 UA74_27105 384d675f00313222a726a0b282a60380 539 SUPERFAMILY SSF52540 301 526 1.51E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_27105 384d675f00313222a726a0b282a60380 539 SMART SM00382 320 514 7.6E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_27105 384d675f00313222a726a0b282a60380 539 SMART SM00382 67 256 1.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_27105 384d675f00313222a726a0b282a60380 539 Gene3D G3DSA:3.40.50.300 302 534 3.4E-45 T 12-10-2018 UA74_27105 384d675f00313222a726a0b282a60380 539 SUPERFAMILY SSF52540 41 260 6.71E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_27105 384d675f00313222a726a0b282a60380 539 ProSitePatterns PS00211 ABC transporters family signature. 438 452 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_27105 384d675f00313222a726a0b282a60380 539 Pfam PF00005 ABC transporter 313 465 4.5E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_27105 384d675f00313222a726a0b282a60380 539 Pfam PF00005 ABC transporter 58 208 1.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_27105 384d675f00313222a726a0b282a60380 539 Gene3D G3DSA:3.40.50.300 29 275 2.3E-56 T 12-10-2018 UA74_18275 d7708e48f15080a4092d87cae7679c35 282 SMART SM00530 15 70 0.0016 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_18275 d7708e48f15080a4092d87cae7679c35 282 Pfam PF13560 Helix-turn-helix domain 11 70 3.0E-9 T 12-10-2018 UA74_18275 d7708e48f15080a4092d87cae7679c35 282 Gene3D G3DSA:1.10.260.40 7 77 1.0E-7 T 12-10-2018 UA74_18275 d7708e48f15080a4092d87cae7679c35 282 SUPERFAMILY SSF47413 9 66 9.38E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_16415 b0a888055cd31a133425b405fc3d2d7d 230 SUPERFAMILY SSF46894 150 215 2.21E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_16415 b0a888055cd31a133425b405fc3d2d7d 230 Gene3D G3DSA:1.10.10.10 154 215 2.4E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16415 b0a888055cd31a133425b405fc3d2d7d 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 208 2.2E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16415 b0a888055cd31a133425b405fc3d2d7d 230 SMART SM00421 152 209 1.6E-4 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_16415 b0a888055cd31a133425b405fc3d2d7d 230 Pfam PF08448 PAS fold 35 142 2.8E-6 T 12-10-2018 IPR013656 PAS fold-4 UA74_16415 b0a888055cd31a133425b405fc3d2d7d 230 Gene3D G3DSA:3.30.450.20 29 138 4.3E-6 T 12-10-2018 UA74_16415 b0a888055cd31a133425b405fc3d2d7d 230 SUPERFAMILY SSF55785 30 133 3.91E-8 T 12-10-2018 IPR035965 PAS domain superfamily UA74_22785 c3a695bec0edcbcd424c5307ed7b3778 251 SUPERFAMILY SSF52540 42 223 1.8E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22785 c3a695bec0edcbcd424c5307ed7b3778 251 Gene3D G3DSA:3.40.50.300 109 224 1.3E-7 T 12-10-2018 UA74_22785 c3a695bec0edcbcd424c5307ed7b3778 251 Gene3D G3DSA:3.40.50.300 36 103 3.2E-7 T 12-10-2018 UA74_22785 c3a695bec0edcbcd424c5307ed7b3778 251 Pfam PF13476 AAA domain 41 78 1.4E-6 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain UA74_22785 c3a695bec0edcbcd424c5307ed7b3778 251 SMART SM00382 48 226 9.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_04920 75650fba66382716a71073529c686098 366 SUPERFAMILY SSF75620 28 364 6.28E-118 T 12-10-2018 UA74_04920 75650fba66382716a71073529c686098 366 Gene3D G3DSA:1.20.58.410 2 114 6.3E-26 T 12-10-2018 UA74_04920 75650fba66382716a71073529c686098 366 SMART SM00937 83 193 1.3E-42 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 UA74_04920 75650fba66382716a71073529c686098 366 Gene3D G3DSA:3.30.160.20 224 318 2.3E-86 T 12-10-2018 UA74_04920 75650fba66382716a71073529c686098 366 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 362 4.7E-150 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 UA74_04920 75650fba66382716a71073529c686098 366 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 243 259 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_04920 75650fba66382716a71073529c686098 366 Gene3D G3DSA:3.30.70.1660 128 356 2.3E-86 T 12-10-2018 UA74_04920 75650fba66382716a71073529c686098 366 Pfam PF00472 RF-1 domain 230 335 1.9E-37 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_04920 75650fba66382716a71073529c686098 366 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 363 36.281 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 UA74_04920 75650fba66382716a71073529c686098 366 Pfam PF03462 PCRF domain 29 218 2.0E-52 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 SUPERFAMILY SSF49899 624 819 5.7E-33 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 SUPERFAMILY SSF49303 218 312 1.32E-11 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 Gene3D G3DSA:2.60.40.10 217 312 5.5E-11 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 Gene3D G3DSA:2.60.120.200 621 818 7.9E-37 T 12-10-2018 UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 SUPERFAMILY SSF49785 43 215 3.04E-44 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 SMART SM00560 680 812 7.3E-21 T 12-10-2018 IPR006558 LamG-like jellyroll fold UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 SUPERFAMILY SSF51445 308 595 6.1E-57 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 Gene3D G3DSA:3.20.20.80 322 599 4.7E-47 T 12-10-2018 UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 89 209 5.7E-11 T 12-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 664 815 6.4E-27 T 12-10-2018 UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 Gene3D G3DSA:2.60.120.260 47 215 7.1E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_18330 d284dcb5333b6bd7ae5081006a29edaf 823 Pfam PF00703 Glycosyl hydrolases family 2 251 311 6.5E-9 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 UA74_05125 aea1513c50c0b59173055ba06d2efbad 84 Pfam PF00550 Phosphopantetheine attachment site 8 71 1.6E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_05125 aea1513c50c0b59173055ba06d2efbad 84 Gene3D G3DSA:1.10.1200.10 2 77 2.3E-16 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05125 aea1513c50c0b59173055ba06d2efbad 84 SUPERFAMILY SSF47336 4 79 1.96E-15 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05125 aea1513c50c0b59173055ba06d2efbad 84 SMART SM00823 Phosphopantetheine attachment site 5 76 1.6E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_22145 73a721bd838d482a473ebf411b6fc70e 657 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 124 532 2.8E-70 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_22145 73a721bd838d482a473ebf411b6fc70e 657 SUPERFAMILY SSF53850 105 638 1.3E-81 T 12-10-2018 UA74_22145 73a721bd838d482a473ebf411b6fc70e 657 Gene3D G3DSA:3.40.190.10 83 365 1.0E-42 T 12-10-2018 UA74_22145 73a721bd838d482a473ebf411b6fc70e 657 Gene3D G3DSA:3.10.105.10 366 613 2.5E-37 T 12-10-2018 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 SUPERFAMILY SSF81338 6 242 5.49E-59 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 ProSitePatterns PS00221 MIP family signature. 64 72 - T 12-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 Gene3D G3DSA:1.20.1080.10 2 244 1.0E-66 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 46 70 8.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 5 24 8.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 138 156 8.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 176 198 8.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 223 243 8.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 PRINTS PR00783 Major intrinsic protein family signature 83 102 8.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UA74_26975 33e42cd49f46c72b762f526c85d844de 245 Pfam PF00230 Major intrinsic protein 6 240 1.2E-37 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UA74_14990 737d4286981ed325e27b6bf97091bf48 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 153 3.1E-13 T 12-10-2018 UA74_14990 737d4286981ed325e27b6bf97091bf48 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 163 187 3.1E-13 T 12-10-2018 UA74_14990 737d4286981ed325e27b6bf97091bf48 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 42 66 3.1E-13 T 12-10-2018 UA74_14990 737d4286981ed325e27b6bf97091bf48 451 SUPERFAMILY SSF103473 13 446 6.8E-56 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_14990 737d4286981ed325e27b6bf97091bf48 451 Pfam PF07690 Major Facilitator Superfamily 44 393 3.5E-40 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_14990 737d4286981ed325e27b6bf97091bf48 451 Gene3D G3DSA:1.20.1720.10 40 235 3.8E-49 T 12-10-2018 UA74_14990 737d4286981ed325e27b6bf97091bf48 451 Gene3D G3DSA:1.20.1250.20 297 449 5.8E-6 T 12-10-2018 UA74_25120 ab6c6efe71f421567473d90ee0298e82 312 Pfam PF00520 Ion transport protein 14 223 8.4E-47 T 12-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 UA74_25120 ab6c6efe71f421567473d90ee0298e82 312 SUPERFAMILY SSF81324 13 223 3.34E-39 T 12-10-2018 UA74_25120 ab6c6efe71f421567473d90ee0298e82 312 Gene3D G3DSA:1.20.120.350 4 116 2.0E-29 T 12-10-2018 IPR027359 Voltage-dependent channel domain superfamily UA74_25120 ab6c6efe71f421567473d90ee0298e82 312 Gene3D G3DSA:1.10.287.70 117 214 3.0E-33 T 12-10-2018 UA74_07260 707a3cf4a00b453dd20c6f1b50f39593 668 Gene3D G3DSA:2.60.40.1180 577 668 3.6E-35 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_07260 707a3cf4a00b453dd20c6f1b50f39593 668 SUPERFAMILY SSF51445 212 571 5.7E-79 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07260 707a3cf4a00b453dd20c6f1b50f39593 668 Gene3D G3DSA:1.20.58.280 105 186 2.2E-55 T 12-10-2018 UA74_07260 707a3cf4a00b453dd20c6f1b50f39593 668 Gene3D G3DSA:2.60.40.10 16 205 2.2E-55 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_07260 707a3cf4a00b453dd20c6f1b50f39593 668 SMART SM00642 211 546 6.0E-5 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07260 707a3cf4a00b453dd20c6f1b50f39593 668 Pfam PF11896 Domain of unknown function (DUF3416) 15 205 2.7E-53 T 12-10-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 UA74_07260 707a3cf4a00b453dd20c6f1b50f39593 668 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 13 667 44.933 T 12-10-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 UA74_07260 707a3cf4a00b453dd20c6f1b50f39593 668 Gene3D G3DSA:3.20.20.80 206 576 1.4E-162 T 12-10-2018 UA74_19970 c2457ab76a932c29c4dff94936c3e7a1 609 SUPERFAMILY SSF101473 402 605 1.44E-41 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_19970 c2457ab76a932c29c4dff94936c3e7a1 609 Gene3D G3DSA:1.25.40.340 397 606 3.5E-48 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_19970 c2457ab76a932c29c4dff94936c3e7a1 609 Gene3D G3DSA:3.40.50.10440 12 181 8.6E-50 T 12-10-2018 UA74_19970 c2457ab76a932c29c4dff94936c3e7a1 609 Pfam PF02733 Dak1 domain 18 330 4.6E-106 T 12-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_19970 c2457ab76a932c29c4dff94936c3e7a1 609 SUPERFAMILY SSF82549 11 333 1.96E-102 T 12-10-2018 UA74_19970 c2457ab76a932c29c4dff94936c3e7a1 609 Pfam PF02734 DAK2 domain 429 602 1.7E-42 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_19970 c2457ab76a932c29c4dff94936c3e7a1 609 SMART SM01120 428 604 8.2E-52 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_19970 c2457ab76a932c29c4dff94936c3e7a1 609 Gene3D G3DSA:3.30.1180.20 183 335 7.4E-44 T 12-10-2018 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Gene3D G3DSA:2.130.10.10 1051 1277 8.8E-49 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Gene3D G3DSA:2.130.10.10 714 900 1.1E-43 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SUPERFAMILY SSF50978 945 1267 1.34E-53 T 12-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 964 978 - T 12-10-2018 IPR019775 WD40 repeat, conserved site UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Gene3D G3DSA:2.130.10.10 901 1049 3.4E-29 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 697 711 - T 12-10-2018 IPR019775 WD40 repeat, conserved site UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 PRINTS PR00320 G protein beta WD-40 repeat signature 788 802 9.3E-7 T 12-10-2018 IPR020472 G-protein beta WD-40 repeat UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 PRINTS PR00320 G protein beta WD-40 repeat signature 1153 1167 9.3E-7 T 12-10-2018 IPR020472 G-protein beta WD-40 repeat UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 PRINTS PR00320 G protein beta WD-40 repeat signature 697 711 9.3E-7 T 12-10-2018 IPR020472 G-protein beta WD-40 repeat UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 788 802 - T 12-10-2018 IPR019775 WD40 repeat, conserved site UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Gene3D G3DSA:2.130.10.10 565 713 2.7E-20 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 776 801 3.3E-4 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 945 977 0.0013 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 1180 1212 1.1E-7 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 1099 1122 0.024 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 1226 1265 0.011 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 815 847 3.6E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 1141 1166 4.5E-6 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 905 939 5.3E-4 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 Pfam PF00400 WD domain, G-beta repeat 679 710 4.2E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SUPERFAMILY SSF52540 78 304 3.68E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 926 940 - T 12-10-2018 IPR019775 WD40 repeat, conserved site UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SUPERFAMILY SSF50998 623 942 9.42E-62 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 941 977 0.45 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 763 801 0.0031 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1219 1266 0.06 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 717 756 1.8 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 857 893 0.73 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 983 1031 50.0 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 671 710 1.2E-6 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 625 664 6.3E-4 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 808 847 2.4E-6 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1037 1073 3.7 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1123 1166 1.2E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1083 1122 0.32 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 1170 1212 7.7E-9 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_18355 a6bb8db14e136d443f16aef6f1529ae6 1304 SMART SM00320 900 939 1.3E-5 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_26385 95f6e9f5b99a3625f223e161aa63285c 388 SUPERFAMILY SSF53223 18 166 3.09E-49 T 12-10-2018 UA74_26385 95f6e9f5b99a3625f223e161aa63285c 388 SMART SM00919 168 388 8.7E-102 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UA74_26385 95f6e9f5b99a3625f223e161aa63285c 388 Pfam PF00390 Malic enzyme, N-terminal domain 33 119 1.3E-19 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_26385 95f6e9f5b99a3625f223e161aa63285c 388 Pfam PF03949 Malic enzyme, NAD binding domain 170 387 8.6E-18 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UA74_26385 95f6e9f5b99a3625f223e161aa63285c 388 SMART SM01274 23 156 7.4E-68 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_26385 95f6e9f5b99a3625f223e161aa63285c 388 SUPERFAMILY SSF51735 168 387 2.84E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_26385 95f6e9f5b99a3625f223e161aa63285c 388 PIRSF PIRSF000106 33 388 6.6E-64 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UA74_26385 95f6e9f5b99a3625f223e161aa63285c 388 Gene3D G3DSA:3.40.50.720 166 388 1.2E-66 T 12-10-2018 UA74_26385 95f6e9f5b99a3625f223e161aa63285c 388 Gene3D G3DSA:3.40.50.10380 11 165 1.6E-61 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 UA74_29300 312e71282facffc896f33d9ed07a7063 292 Pfam PF00376 MerR family regulatory protein 4 41 1.1E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_29300 312e71282facffc896f33d9ed07a7063 292 SUPERFAMILY SSF46955 3 108 6.96E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_29300 312e71282facffc896f33d9ed07a7063 292 SMART SM00422 3 72 1.1E-21 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_29300 312e71282facffc896f33d9ed07a7063 292 Gene3D G3DSA:1.10.1660.10 5 187 8.3E-24 T 12-10-2018 UA74_29300 312e71282facffc896f33d9ed07a7063 292 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 9.6E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_29300 312e71282facffc896f33d9ed07a7063 292 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 9.6E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_29300 312e71282facffc896f33d9ed07a7063 292 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 9.6E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15580 789bdf3a70c7d098cc6d17e9f71eb5a9 277 Pfam PF02673 Bacitracin resistance protein BacA 6 264 5.1E-84 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 UA74_15580 789bdf3a70c7d098cc6d17e9f71eb5a9 277 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 262 1.9E-84 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 UA74_15580 789bdf3a70c7d098cc6d17e9f71eb5a9 277 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 269 18.071 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 Gene3D G3DSA:1.10.10.10 4 79 1.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 SMART SM00345 15 74 9.7E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.6E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.6E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 Pfam PF07729 FCD domain 94 211 3.0E-22 T 12-10-2018 IPR011711 GntR, C-terminal UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 SUPERFAMILY SSF46785 6 78 1.61E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 SMART SM00895 94 219 5.1E-19 T 12-10-2018 IPR011711 GntR, C-terminal UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 SUPERFAMILY SSF48008 90 224 6.8E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.9E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_09060 4d23ab9a1647668fe36b8330e4b70c38 234 Gene3D G3DSA:1.20.120.530 88 222 6.0E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_16285 f3041155cb498854599da5546e293934 80 Gene3D G3DSA:3.30.420.10 1 79 3.5E-11 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_16285 f3041155cb498854599da5546e293934 80 SUPERFAMILY SSF53098 2 73 1.15E-13 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_16285 f3041155cb498854599da5546e293934 80 Pfam PF00665 Integrase core domain 2 73 1.5E-10 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 UA74_15775 1e2c075dc63dcbd8f45a454ed102a019 514 Gene3D G3DSA:3.40.50.12780 5 386 1.4E-54 T 12-10-2018 UA74_15775 1e2c075dc63dcbd8f45a454ed102a019 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_15775 1e2c075dc63dcbd8f45a454ed102a019 514 Gene3D G3DSA:3.30.300.30 393 509 4.0E-5 T 12-10-2018 UA74_15775 1e2c075dc63dcbd8f45a454ed102a019 514 SUPERFAMILY SSF56801 5 502 2.88E-70 T 12-10-2018 UA74_15775 1e2c075dc63dcbd8f45a454ed102a019 514 Pfam PF00501 AMP-binding enzyme 12 393 2.7E-54 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_18775 473bdd877b07c2a932d63ecfe5aa327a 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 285 1.1E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_18775 473bdd877b07c2a932d63ecfe5aa327a 292 SUPERFAMILY SSF161098 23 292 5.63E-64 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18775 473bdd877b07c2a932d63ecfe5aa327a 292 Gene3D G3DSA:1.10.3720.10 18 283 3.5E-53 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20585 eeaafbed9062beb53fd8c5787d0db04f 1048 SMART SM00487 108 328 2.6E-14 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_20585 eeaafbed9062beb53fd8c5787d0db04f 1048 SUPERFAMILY SSF52540 106 333 5.83E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20585 eeaafbed9062beb53fd8c5787d0db04f 1048 Gene3D G3DSA:3.40.50.10810 110 391 9.3E-65 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily UA74_20585 eeaafbed9062beb53fd8c5787d0db04f 1048 Pfam PF00271 Helicase conserved C-terminal domain 508 615 1.2E-15 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_20585 eeaafbed9062beb53fd8c5787d0db04f 1048 SUPERFAMILY SSF52540 243 629 4.16E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20585 eeaafbed9062beb53fd8c5787d0db04f 1048 SMART SM00490 526 615 1.5E-15 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_20585 eeaafbed9062beb53fd8c5787d0db04f 1048 Gene3D G3DSA:3.40.50.300 439 630 6.5E-35 T 12-10-2018 UA74_20585 eeaafbed9062beb53fd8c5787d0db04f 1048 Pfam PF00176 SNF2 family N-terminal domain 132 311 8.8E-8 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 UA74_03885 dac1c18c016821d40f8def9d890faf48 439 SUPERFAMILY SSF53850 36 431 1.02E-51 T 12-10-2018 UA74_03885 dac1c18c016821d40f8def9d890faf48 439 Pfam PF13416 Bacterial extracellular solute-binding protein 61 346 3.3E-15 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_03885 dac1c18c016821d40f8def9d890faf48 439 Gene3D G3DSA:3.40.190.10 32 431 7.8E-57 T 12-10-2018 UA74_24020 b9cf769364eaf7dd0a6a2fb6f4be915c 287 SUPERFAMILY SSF63380 28 125 4.12E-15 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_24020 b9cf769364eaf7dd0a6a2fb6f4be915c 287 SUPERFAMILY SSF52343 120 281 1.44E-18 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_24020 b9cf769364eaf7dd0a6a2fb6f4be915c 287 PIRSF PIRSF006816 27 287 3.1E-43 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 UA74_24020 b9cf769364eaf7dd0a6a2fb6f4be915c 287 Gene3D G3DSA:3.40.50.80 128 236 1.3E-7 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_24020 b9cf769364eaf7dd0a6a2fb6f4be915c 287 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 79 89 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 UA74_24020 b9cf769364eaf7dd0a6a2fb6f4be915c 287 Gene3D G3DSA:2.10.240.10 245 283 2.3E-10 T 12-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily UA74_24020 b9cf769364eaf7dd0a6a2fb6f4be915c 287 Gene3D G3DSA:2.40.30.10 26 123 2.1E-20 T 12-10-2018 UA74_24020 b9cf769364eaf7dd0a6a2fb6f4be915c 287 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 245 281 1.9E-9 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UA74_11595 1185fb410c25d5fe7f29316d90b37eda 160 SUPERFAMILY SSF82784 4 150 1.96E-39 T 12-10-2018 IPR036102 OsmC/Ohr superfamily UA74_11595 1185fb410c25d5fe7f29316d90b37eda 160 Gene3D G3DSA:3.30.300.20 1 150 2.6E-49 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_11595 1185fb410c25d5fe7f29316d90b37eda 160 Pfam PF02566 OsmC-like protein 51 147 1.1E-11 T 12-10-2018 IPR003718 OsmC/Ohr family UA74_08885 f389e07a0345e271eea0198863c9701f 400 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 282 369 2.2E-21 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_08885 f389e07a0345e271eea0198863c9701f 400 Gene3D G3DSA:3.40.50.300 50 378 1.2E-95 T 12-10-2018 UA74_08885 f389e07a0345e271eea0198863c9701f 400 ProSitePatterns PS00211 ABC transporters family signature. 205 219 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_08885 f389e07a0345e271eea0198863c9701f 400 Pfam PF00005 ABC transporter 72 232 2.6E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_08885 f389e07a0345e271eea0198863c9701f 400 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 284 348 1.4E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_08885 f389e07a0345e271eea0198863c9701f 400 SMART SM00382 80 282 1.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_08885 f389e07a0345e271eea0198863c9701f 400 SUPERFAMILY SSF52540 52 303 1.14E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_05555 8aaa00e6a4ad57108317733c6632557d 336 SUPERFAMILY SSF53850 47 283 3.8E-10 T 12-10-2018 UA74_05555 8aaa00e6a4ad57108317733c6632557d 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 61 327 4.0E-44 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 UA74_05555 8aaa00e6a4ad57108317733c6632557d 336 Gene3D G3DSA:3.40.190.10 140 258 1.1E-72 T 12-10-2018 UA74_05555 8aaa00e6a4ad57108317733c6632557d 336 Gene3D G3DSA:3.40.190.150 45 322 1.1E-72 T 12-10-2018 UA74_05555 8aaa00e6a4ad57108317733c6632557d 336 PIRSF PIRSF017082 4 331 6.1E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 UA74_21810 4173b5b21f6aca28982088727da3553b 394 SUPERFAMILY SSF110738 11 386 3.53E-112 T 12-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 UA74_21810 4173b5b21f6aca28982088727da3553b 394 PIRSF PIRSF006078 10 389 2.6E-105 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_21810 4173b5b21f6aca28982088727da3553b 394 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 11 385 2.4E-129 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_21810 4173b5b21f6aca28982088727da3553b 394 Gene3D G3DSA:3.40.50.10350 10 373 3.0E-121 T 12-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold UA74_21810 4173b5b21f6aca28982088727da3553b 394 Pfam PF02595 Glycerate kinase family 12 384 5.6E-128 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_21810 4173b5b21f6aca28982088727da3553b 394 Gene3D G3DSA:3.90.1510.10 51 287 3.0E-121 T 12-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 UA74_15745 52a88a53bcc326e52c10d4fa5c7fac29 160 Gene3D G3DSA:3.90.79.10 2 148 1.0E-32 T 12-10-2018 UA74_15745 52a88a53bcc326e52c10d4fa5c7fac29 160 Pfam PF00293 NUDIX domain 22 135 5.1E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_15745 52a88a53bcc326e52c10d4fa5c7fac29 160 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_15745 52a88a53bcc326e52c10d4fa5c7fac29 160 SUPERFAMILY SSF55811 19 149 2.37E-27 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_25505 bc538159150a5f8ad7ffdb634a8c0971 538 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 439 1.2E-63 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UA74_25505 bc538159150a5f8ad7ffdb634a8c0971 538 Gene3D G3DSA:1.20.1730.10 22 501 1.0E-106 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily UA74_25505 bc538159150a5f8ad7ffdb634a8c0971 538 Pfam PF00474 Sodium:solute symporter family 33 436 1.0E-33 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UA74_26685 9c188cd675ab85b49ebbe8d6f6525703 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 307 8.9E-79 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_26685 9c188cd675ab85b49ebbe8d6f6525703 333 SUPERFAMILY SSF51735 1 319 2.69E-97 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_26685 9c188cd675ab85b49ebbe8d6f6525703 333 Gene3D G3DSA:3.90.25.10 193 314 6.1E-120 T 12-10-2018 UA74_26685 9c188cd675ab85b49ebbe8d6f6525703 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 321 7.2E-133 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 UA74_26685 9c188cd675ab85b49ebbe8d6f6525703 333 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_26685 9c188cd675ab85b49ebbe8d6f6525703 333 Gene3D G3DSA:3.40.50.720 2 306 6.1E-120 T 12-10-2018 UA74_06170 82316a13f0626edb1cd366480402131c 197 Gene3D G3DSA:1.10.1760.20 22 193 5.6E-46 T 12-10-2018 UA74_06170 82316a13f0626edb1cd366480402131c 197 PIRSF PIRSF016661 13 197 7.9E-37 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 UA74_06170 82316a13f0626edb1cd366480402131c 197 Pfam PF02632 BioY family 51 189 1.4E-34 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 UA74_19355 ffe2ca3ad6aa65cc72f19b0279ff4063 110 SUPERFAMILY SSF103481 11 105 1.28E-19 T 12-10-2018 UA74_19355 ffe2ca3ad6aa65cc72f19b0279ff4063 110 Pfam PF00893 Small Multidrug Resistance protein 7 98 6.4E-25 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 UA74_19355 ffe2ca3ad6aa65cc72f19b0279ff4063 110 Gene3D G3DSA:1.10.3730.20 5 110 1.7E-30 T 12-10-2018 UA74_18975 4be359732f19687b48e4f7e20a85f82f 628 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_18975 4be359732f19687b48e4f7e20a85f82f 628 SMART SM00220 15 273 5.9E-35 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_18975 4be359732f19687b48e4f7e20a85f82f 628 Pfam PF00069 Protein kinase domain 15 264 1.3E-33 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_18975 4be359732f19687b48e4f7e20a85f82f 628 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_18975 4be359732f19687b48e4f7e20a85f82f 628 Gene3D G3DSA:1.10.510.10 96 277 2.6E-41 T 12-10-2018 UA74_18975 4be359732f19687b48e4f7e20a85f82f 628 Gene3D G3DSA:3.30.200.20 5 93 9.8E-17 T 12-10-2018 UA74_18975 4be359732f19687b48e4f7e20a85f82f 628 SUPERFAMILY SSF56112 12 269 2.43E-57 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_22255 a8232a138b800b6aaea5bec074c8d598 176 Gene3D G3DSA:1.10.10.10 4 144 1.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22255 a8232a138b800b6aaea5bec074c8d598 176 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 101 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_22255 a8232a138b800b6aaea5bec074c8d598 176 Pfam PF13463 Winged helix DNA-binding domain 37 101 7.9E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_22255 a8232a138b800b6aaea5bec074c8d598 176 SUPERFAMILY SSF46785 10 142 6.82E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22255 a8232a138b800b6aaea5bec074c8d598 176 SMART SM00347 29 128 6.2E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_26360 b6f23576b252523c3303748d953cf855 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 214 1.4E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_26360 b6f23576b252523c3303748d953cf855 257 SUPERFAMILY SSF161098 23 203 1.24E-33 T 12-10-2018 IPR035906 MetI-like superfamily UA74_26360 b6f23576b252523c3303748d953cf855 257 Gene3D G3DSA:1.10.3720.10 21 209 2.1E-26 T 12-10-2018 IPR035906 MetI-like superfamily UA74_26550 eae2462bdc02dbe4a32b069ac9c2a827 208 Gene3D G3DSA:3.40.50.300 1 200 1.4E-48 T 12-10-2018 UA74_26550 eae2462bdc02dbe4a32b069ac9c2a827 208 SUPERFAMILY SSF52540 1 195 1.15E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26550 eae2462bdc02dbe4a32b069ac9c2a827 208 Pfam PF02223 Thymidylate kinase 2 160 1.5E-20 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 UA74_30140 1e635dac9962e66193405af53743dbdd 566 Gene3D G3DSA:3.20.20.60 229 549 1.5E-88 T 12-10-2018 UA74_30140 1e635dac9962e66193405af53743dbdd 566 Gene3D G3DSA:3.50.30.10 8 227 8.9E-48 T 12-10-2018 UA74_30140 1e635dac9962e66193405af53743dbdd 566 Pfam PF05524 PEP-utilising enzyme, N-terminal 7 124 4.1E-17 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 UA74_30140 1e635dac9962e66193405af53743dbdd 566 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 425 443 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 UA74_30140 1e635dac9962e66193405af53743dbdd 566 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 182 193 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 UA74_30140 1e635dac9962e66193405af53743dbdd 566 SUPERFAMILY SSF47831 34 141 5.36E-17 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 UA74_30140 1e635dac9962e66193405af53743dbdd 566 SUPERFAMILY SSF52009 123 237 3.79E-27 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 UA74_30140 1e635dac9962e66193405af53743dbdd 566 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 248 518 2.8E-74 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 UA74_30140 1e635dac9962e66193405af53743dbdd 566 PIRSF PIRSF000732 2 552 1.0E-137 T 12-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 UA74_30140 1e635dac9962e66193405af53743dbdd 566 Gene3D G3DSA:1.10.274.10 25 144 8.9E-48 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 UA74_30140 1e635dac9962e66193405af53743dbdd 566 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 222 2.7E-21 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 UA74_30140 1e635dac9962e66193405af53743dbdd 566 SUPERFAMILY SSF51621 244 523 1.6E-80 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UA74_30140 1e635dac9962e66193405af53743dbdd 566 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 442 457 3.3E-19 T 12-10-2018 UA74_30140 1e635dac9962e66193405af53743dbdd 566 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 425 440 3.3E-19 T 12-10-2018 UA74_30140 1e635dac9962e66193405af53743dbdd 566 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 280 299 3.3E-19 T 12-10-2018 UA74_30140 1e635dac9962e66193405af53743dbdd 566 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 478 490 3.3E-19 T 12-10-2018 UA74_23875 4f7066e43a1b6480f37379f7af58c013 442 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 225 3.5E-16 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UA74_23875 4f7066e43a1b6480f37379f7af58c013 442 Gene3D G3DSA:3.40.50.720 4 139 1.0E-26 T 12-10-2018 UA74_23875 4f7066e43a1b6480f37379f7af58c013 442 SUPERFAMILY SSF55347 142 334 3.49E-29 T 12-10-2018 UA74_23875 4f7066e43a1b6480f37379f7af58c013 442 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 136 2.6E-17 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_23875 4f7066e43a1b6480f37379f7af58c013 442 SUPERFAMILY SSF51735 7 168 6.99E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12900 0b81414a0fb8ea4f3c51a0f8249977c0 464 Pfam PF01569 PAP2 superfamily 35 146 3.4E-19 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_12900 0b81414a0fb8ea4f3c51a0f8249977c0 464 SMART SM00014 33 142 3.9E-20 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UA74_12900 0b81414a0fb8ea4f3c51a0f8249977c0 464 SUPERFAMILY SSF48317 7 145 1.44E-37 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily UA74_12900 0b81414a0fb8ea4f3c51a0f8249977c0 464 Gene3D G3DSA:3.40.50.10330 167 287 3.2E-13 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 UA74_12900 0b81414a0fb8ea4f3c51a0f8249977c0 464 SMART SM00046 169 297 2.9E-8 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_12900 0b81414a0fb8ea4f3c51a0f8249977c0 464 SUPERFAMILY SSF111331 170 457 2.4E-42 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily UA74_12900 0b81414a0fb8ea4f3c51a0f8249977c0 464 Gene3D G3DSA:2.60.200.40 288 447 4.3E-16 T 12-10-2018 UA74_12900 0b81414a0fb8ea4f3c51a0f8249977c0 464 Gene3D G3DSA:1.20.144.10 65 151 1.6E-18 T 12-10-2018 UA74_12900 0b81414a0fb8ea4f3c51a0f8249977c0 464 Pfam PF00781 Diacylglycerol kinase catalytic domain 170 287 1.6E-12 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_17575 3106ddbe5e14fa90ab0f84dc841e14cd 462 SUPERFAMILY SSF52777 207 449 1.11E-28 T 12-10-2018 UA74_17575 3106ddbe5e14fa90ab0f84dc841e14cd 462 Gene3D G3DSA:3.30.559.30 203 450 1.5E-83 T 12-10-2018 UA74_17575 3106ddbe5e14fa90ab0f84dc841e14cd 462 SUPERFAMILY SSF52777 22 199 6.23E-37 T 12-10-2018 UA74_17575 3106ddbe5e14fa90ab0f84dc841e14cd 462 Pfam PF00668 Condensation domain 51 450 7.0E-51 T 12-10-2018 IPR001242 Condensation domain UA74_17575 3106ddbe5e14fa90ab0f84dc841e14cd 462 Gene3D G3DSA:3.30.559.10 22 400 1.5E-83 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 SUPERFAMILY SSF81301 29 178 3.81E-32 T 12-10-2018 UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 Gene3D G3DSA:1.10.3090.10 187 484 1.1E-44 T 12-10-2018 UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 Gene3D G3DSA:3.30.460.10 19 178 9.6E-33 T 12-10-2018 UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 22 496 1.4E-231 T 12-10-2018 IPR014065 tRNA adenylyltransferase UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 SMART SM00471 282 502 4.2E-4 T 12-10-2018 IPR003607 HD/PDEase domain UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 212 271 3.0E-15 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 Pfam PF01966 HD domain 286 411 1.6E-13 T 12-10-2018 IPR006674 HD domain UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 TIGRFAM TIGR00277 HDIG: HDIG domain 283 368 3.9E-17 T 12-10-2018 IPR006675 HDIG domain UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 Pfam PF01743 Poly A polymerase head domain 46 179 1.3E-28 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 UA74_30215 702b2b2f97f7d6f861d71890d4f2a46a 508 SUPERFAMILY SSF81891 183 496 3.79E-60 T 12-10-2018 UA74_26515 2d2b311d819389720f8449405942b4fa 974 Hamap MF_01382 Protein translocase subunit SecA [secA]. 2 831 19.887 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_26515 2d2b311d819389720f8449405942b4fa 974 Pfam PF07517 SecA DEAD-like domain 6 380 2.2E-126 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UA74_26515 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 98 112 2.9E-70 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_26515 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 318 340 2.9E-70 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_26515 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 355 372 2.9E-70 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_26515 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 167 187 2.9E-70 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_26515 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 392 405 2.9E-70 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_26515 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 114 124 2.9E-70 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_26515 2d2b311d819389720f8449405942b4fa 974 PRINTS PR00906 SecA protein signature 60 84 2.9E-70 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_26515 2d2b311d819389720f8449405942b4fa 974 Pfam PF07516 SecA Wing and Scaffold domain 611 828 2.1E-65 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 UA74_26515 2d2b311d819389720f8449405942b4fa 974 Pfam PF01043 SecA preprotein cross-linking domain 229 337 2.0E-36 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 UA74_26515 2d2b311d819389720f8449405942b4fa 974 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 25 816 0.0 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_26515 2d2b311d819389720f8449405942b4fa 974 Gene3D G3DSA:3.90.1440.10 226 347 9.3E-180 T 12-10-2018 UA74_26515 2d2b311d819389720f8449405942b4fa 974 Gene3D G3DSA:3.40.50.300 20 394 9.3E-180 T 12-10-2018 UA74_26515 2d2b311d819389720f8449405942b4fa 974 SMART SM00957 3 381 2.2E-275 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UA74_26515 2d2b311d819389720f8449405942b4fa 974 ProSitePatterns PS01312 SecA family signature. 479 494 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 UA74_26515 2d2b311d819389720f8449405942b4fa 974 Gene3D G3DSA:1.10.3060.10 615 832 1.2E-71 T 12-10-2018 UA74_26515 2d2b311d819389720f8449405942b4fa 974 Gene3D G3DSA:3.40.50.300 396 613 3.6E-91 T 12-10-2018 UA74_26515 2d2b311d819389720f8449405942b4fa 974 SUPERFAMILY SSF52540 9 394 2.78E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26515 2d2b311d819389720f8449405942b4fa 974 SUPERFAMILY SSF81886 614 834 7.72E-70 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily UA74_26515 2d2b311d819389720f8449405942b4fa 974 SMART SM00958 225 337 5.9E-66 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 UA74_26515 2d2b311d819389720f8449405942b4fa 974 SUPERFAMILY SSF52540 395 612 1.16E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26515 2d2b311d819389720f8449405942b4fa 974 SUPERFAMILY SSF81767 224 347 6.54E-44 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 UA74_07240 fdbcdec48b7c1df5d23a00bea0d9d67c 280 SUPERFAMILY SSF55315 13 109 2.82E-8 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_07240 fdbcdec48b7c1df5d23a00bea0d9d67c 280 SUPERFAMILY SSF75217 116 277 1.11E-38 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_07240 fdbcdec48b7c1df5d23a00bea0d9d67c 280 Gene3D G3DSA:3.30.1330.30 14 113 1.6E-20 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_07240 fdbcdec48b7c1df5d23a00bea0d9d67c 280 Gene3D G3DSA:3.40.1280.10 114 279 8.8E-53 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_07240 fdbcdec48b7c1df5d23a00bea0d9d67c 280 Pfam PF00588 SpoU rRNA Methylase family 123 268 1.1E-32 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 Gene3D G3DSA:1.25.40.10 543 640 4.3E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 Pfam PF13432 Tetratricopeptide repeat 618 676 0.0059 T 12-10-2018 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 Pfam PF13432 Tetratricopeptide repeat 752 806 2.0E-5 T 12-10-2018 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 Pfam PF13432 Tetratricopeptide repeat 546 608 1.7E-7 T 12-10-2018 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 610 643 0.03 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 712 745 0.13 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 576 609 0.074 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 542 575 2.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 644 677 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 814 847 1.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 780 813 1.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 678 711 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SMART SM00028 746 779 0.0012 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 Pfam PF13191 AAA ATPase domain 20 239 3.4E-9 T 12-10-2018 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SUPERFAMILY SSF48452 543 851 8.09E-45 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 SUPERFAMILY SSF52540 18 313 9.91E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 Gene3D G3DSA:1.25.40.10 641 711 1.2E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 Gene3D G3DSA:1.25.40.10 712 854 3.9E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11140 7e2b840642201d9facd3124dc20f25ee 875 Gene3D G3DSA:3.40.50.300 3 122 2.9E-6 T 12-10-2018 UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 Gene3D G3DSA:3.40.50.720 2 251 1.7E-77 T 12-10-2018 UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 249 2.4E-58 T 12-10-2018 UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 188 1.5E-4 T 12-10-2018 UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.0E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.0E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.0E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15120 ed4c76fc728fdaa8d9512fe51b95c1fa 252 SUPERFAMILY SSF51735 4 251 9.23E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_11680 fdf54f1d30c364421bb71ddf15a62eea 241 SUPERFAMILY SSF49879 127 232 2.49E-18 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 UA74_11680 fdf54f1d30c364421bb71ddf15a62eea 241 SMART SM00240 153 210 1.3E-7 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_11680 fdf54f1d30c364421bb71ddf15a62eea 241 Gene3D G3DSA:2.60.200.20 119 239 8.0E-18 T 12-10-2018 UA74_11680 fdf54f1d30c364421bb71ddf15a62eea 241 Pfam PF00498 FHA domain 156 228 6.0E-11 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_17845 dd5765001b2b7ca5ba6f7970f0a167e2 387 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 51 3.1E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_17845 dd5765001b2b7ca5ba6f7970f0a167e2 387 SMART SM00354 6 77 1.5E-9 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_17845 dd5765001b2b7ca5ba6f7970f0a167e2 387 SUPERFAMILY SSF47413 6 52 5.63E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_17845 dd5765001b2b7ca5ba6f7970f0a167e2 387 SUPERFAMILY SSF53822 128 386 4.32E-50 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_17845 dd5765001b2b7ca5ba6f7970f0a167e2 387 Gene3D G3DSA:1.10.260.40 1 62 2.6E-17 T 12-10-2018 UA74_17845 dd5765001b2b7ca5ba6f7970f0a167e2 387 Pfam PF13377 Periplasmic binding protein-like domain 226 386 9.9E-31 T 12-10-2018 UA74_17845 dd5765001b2b7ca5ba6f7970f0a167e2 387 Gene3D G3DSA:3.40.50.2300 149 367 2.6E-53 T 12-10-2018 UA74_17845 dd5765001b2b7ca5ba6f7970f0a167e2 387 Gene3D G3DSA:3.40.50.2300 217 348 2.6E-53 T 12-10-2018 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 SMART SM00896 767 860 7.7E-40 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 SMART SM00873 252 425 6.1E-78 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 SMART SM00874 441 514 1.8E-18 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.30.930.10 529 756 1.1E-53 T 12-10-2018 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.30.70.380 768 861 6.5E-26 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 Pfam PF03147 Ferredoxin-fold anticodon binding domain 767 860 2.2E-24 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF54991 765 860 1.7E-26 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF55681 510 755 5.96E-40 T 12-10-2018 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 854 38.92 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 Pfam PF01588 Putative tRNA binding domain 109 181 1.1E-9 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.50.40.10 239 435 3.4E-71 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 Gene3D G3DSA:3.30.56.10 441 518 8.4E-15 T 12-10-2018 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF50249 108 232 4.06E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 108 860 3.6E-161 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 Pfam PF03483 B3/4 domain 252 424 8.1E-62 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF56037 239 437 4.45E-65 T 12-10-2018 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 Pfam PF03484 tRNA synthetase B5 domain 448 514 3.7E-12 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UA74_21665 9abf2f84273a8c3b14e145bfe2ca3f49 861 SUPERFAMILY SSF46955 443 518 3.11E-12 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_16720 fa5cc3e812844b76212f0c9e0f3846f2 139 Pfam PF12802 MarR family 30 83 1.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_16720 fa5cc3e812844b76212f0c9e0f3846f2 139 SMART SM00347 25 124 0.0022 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_16720 fa5cc3e812844b76212f0c9e0f3846f2 139 SUPERFAMILY SSF46785 8 120 3.12E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_16720 fa5cc3e812844b76212f0c9e0f3846f2 139 Gene3D G3DSA:1.10.10.10 9 133 2.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_06215 629f7d4e63a1dbc31f8d20f338f841fa 151 Gene3D G3DSA:3.40.140.10 1 143 8.6E-34 T 12-10-2018 UA74_06215 629f7d4e63a1dbc31f8d20f338f841fa 151 SMART SM00232 1 136 5.4E-27 T 12-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 UA74_06215 629f7d4e63a1dbc31f8d20f338f841fa 151 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 120 5.0E-28 T 12-10-2018 IPR028090 JAB domain, prokaryotic UA74_06215 629f7d4e63a1dbc31f8d20f338f841fa 151 SUPERFAMILY SSF102712 2 130 4.84E-27 T 12-10-2018 UA74_21030 995be2fe627d00976927076701f5149b 402 Gene3D G3DSA:3.90.180.10 43 359 1.3E-26 T 12-10-2018 UA74_21030 995be2fe627d00976927076701f5149b 402 SUPERFAMILY SSF50129 25 185 2.67E-23 T 12-10-2018 IPR011032 GroES-like superfamily UA74_21030 995be2fe627d00976927076701f5149b 402 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 50 113 3.6E-10 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_21030 995be2fe627d00976927076701f5149b 402 Gene3D G3DSA:3.40.50.720 164 326 1.3E-26 T 12-10-2018 UA74_25495 485f969221e2e7c747bb6976b132768e 499 SUPERFAMILY SSF52540 295 498 4.31E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25495 485f969221e2e7c747bb6976b132768e 499 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 226 499 57.559 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 UA74_25495 485f969221e2e7c747bb6976b132768e 499 SMART SM00963 203 283 5.1E-15 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_25495 485f969221e2e7c747bb6976b132768e 499 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 227 498 1.4E-102 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 UA74_25495 485f969221e2e7c747bb6976b132768e 499 SUPERFAMILY SSF47364 198 277 8.9E-16 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 UA74_25495 485f969221e2e7c747bb6976b132768e 499 Pfam PF02881 SRP54-type protein, helical bundle domain 218 277 2.8E-7 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_25495 485f969221e2e7c747bb6976b132768e 499 Pfam PF00448 SRP54-type protein, GTPase domain 300 498 2.8E-72 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_25495 485f969221e2e7c747bb6976b132768e 499 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 472 485 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_25495 485f969221e2e7c747bb6976b132768e 499 Gene3D G3DSA:1.20.120.140 201 497 5.5E-98 T 12-10-2018 UA74_25495 485f969221e2e7c747bb6976b132768e 499 SMART SM00962 300 499 1.6E-100 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UA74_25495 485f969221e2e7c747bb6976b132768e 499 Gene3D G3DSA:3.40.50.300 292 487 5.5E-98 T 12-10-2018 UA74_25495 485f969221e2e7c747bb6976b132768e 499 SMART SM00382 299 449 4.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_30040 ad63fa940338d12ba5a1494fc37082bd 319 Pfam PF00005 ABC transporter 25 168 3.7E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_30040 ad63fa940338d12ba5a1494fc37082bd 319 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_30040 ad63fa940338d12ba5a1494fc37082bd 319 Gene3D G3DSA:3.40.50.300 2 237 8.6E-67 T 12-10-2018 UA74_30040 ad63fa940338d12ba5a1494fc37082bd 319 SMART SM00382 34 217 3.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_30040 ad63fa940338d12ba5a1494fc37082bd 319 SUPERFAMILY SSF52540 8 230 1.05E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_30040 ad63fa940338d12ba5a1494fc37082bd 319 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 17 308 5.2E-94 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_21325 9c083b42b3f558d044e87d3d7a03264a 461 Gene3D G3DSA:3.50.30.30 113 245 2.8E-89 T 12-10-2018 UA74_21325 9c083b42b3f558d044e87d3d7a03264a 461 Pfam PF02225 PA domain 138 228 3.9E-7 T 12-10-2018 IPR003137 PA domain UA74_21325 9c083b42b3f558d044e87d3d7a03264a 461 Gene3D G3DSA:3.40.630.10 74 447 2.8E-89 T 12-10-2018 UA74_21325 9c083b42b3f558d044e87d3d7a03264a 461 SUPERFAMILY SSF52025 132 222 4.58E-8 T 12-10-2018 UA74_21325 9c083b42b3f558d044e87d3d7a03264a 461 SUPERFAMILY SSF53187 52 459 9.67E-57 T 12-10-2018 UA74_21325 9c083b42b3f558d044e87d3d7a03264a 461 Pfam PF04389 Peptidase family M28 253 444 1.1E-36 T 12-10-2018 IPR007484 Peptidase M28 UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 6.8E-7 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 6.8E-7 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 6.8E-7 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 SUPERFAMILY SSF46785 9 70 4.81E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 Pfam PF13404 AsnC-type helix-turn-helix domain 10 50 2.1E-6 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 SMART SM00344 10 116 7.8E-22 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 Gene3D G3DSA:3.30.70.920 63 152 9.5E-21 T 12-10-2018 UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 SUPERFAMILY SSF54909 70 154 5.09E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 Gene3D G3DSA:1.10.10.10 6 60 1.4E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04010 fa2f9f2adc8bb27299c72248da6fd760 166 Pfam PF01037 Lrp/AsnC ligand binding domain 84 146 4.8E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_18945 4bfcbcd315457e63c8f348da1e24217f 183 SUPERFAMILY SSF81301 6 166 8.83E-45 T 12-10-2018 UA74_18945 4bfcbcd315457e63c8f348da1e24217f 183 Gene3D G3DSA:3.30.460.10 1 170 2.7E-51 T 12-10-2018 UA74_18945 4bfcbcd315457e63c8f348da1e24217f 183 Pfam PF04229 GrpB protein 5 164 3.4E-47 T 12-10-2018 IPR007344 GrpB/Dephospho-CoA kinase UA74_10665 f000a2e74cc671ded13f08e21f440122 497 Gene3D G3DSA:2.40.50.140 33 128 1.3E-22 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 Gene3D G3DSA:2.40.50.140 129 210 6.8E-9 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 SUPERFAMILY SSF50249 218 300 1.85E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_10665 f000a2e74cc671ded13f08e21f440122 497 SMART SM00316 218 288 3.3E-28 T 12-10-2018 IPR022967 RNA-binding domain, S1 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 SMART SM00316 45 116 1.6E-16 T 12-10-2018 IPR022967 RNA-binding domain, S1 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 SMART SM00316 132 199 2.0E-9 T 12-10-2018 IPR022967 RNA-binding domain, S1 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 SMART SM00316 303 374 4.6E-25 T 12-10-2018 IPR022967 RNA-binding domain, S1 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 Pfam PF00575 S1 RNA binding domain 44 116 8.1E-15 T 12-10-2018 IPR003029 S1 domain GO:0003676 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 Pfam PF00575 S1 RNA binding domain 132 199 2.1E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 Pfam PF00575 S1 RNA binding domain 217 288 8.3E-26 T 12-10-2018 IPR003029 S1 domain GO:0003676 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 Pfam PF00575 S1 RNA binding domain 302 374 5.9E-24 T 12-10-2018 IPR003029 S1 domain GO:0003676 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 SUPERFAMILY SSF50249 288 376 5.28E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_10665 f000a2e74cc671ded13f08e21f440122 497 SUPERFAMILY SSF50249 39 141 8.21E-22 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_10665 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 240 261 3.5E-87 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 357 375 3.5E-87 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 137 153 3.5E-87 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 318 337 3.5E-87 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 183 203 3.5E-87 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 47 65 3.5E-87 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 65 79 3.5E-87 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 113 132 3.5E-87 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 PRINTS PR00681 Ribosomal protein S1 signature 154 171 3.5E-87 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 Gene3D G3DSA:2.40.50.140 295 378 2.9E-29 T 12-10-2018 UA74_10665 f000a2e74cc671ded13f08e21f440122 497 SUPERFAMILY SSF50249 118 202 5.86E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_10665 f000a2e74cc671ded13f08e21f440122 497 Gene3D G3DSA:2.40.50.140 215 294 1.9E-30 T 12-10-2018 UA74_22100 f1c5929fa4ae1d554127ec53db677c3f 407 Gene3D G3DSA:1.20.1250.20 205 385 2.4E-27 T 12-10-2018 UA74_22100 f1c5929fa4ae1d554127ec53db677c3f 407 Gene3D G3DSA:1.20.1250.20 9 187 1.1E-13 T 12-10-2018 UA74_22100 f1c5929fa4ae1d554127ec53db677c3f 407 Pfam PF07690 Major Facilitator Superfamily 13 343 1.1E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_22100 f1c5929fa4ae1d554127ec53db677c3f 407 SUPERFAMILY SSF103473 6 387 1.02E-40 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_28465 628ae1fe74eaca0b073812474c04eab5 140 Gene3D G3DSA:3.30.450.30 10 133 1.3E-44 T 12-10-2018 UA74_28465 628ae1fe74eaca0b073812474c04eab5 140 SMART SM00960 12 102 6.7E-33 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain UA74_28465 628ae1fe74eaca0b073812474c04eab5 140 Pfam PF03259 Roadblock/LC7 domain 13 102 2.8E-24 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain UA74_28465 628ae1fe74eaca0b073812474c04eab5 140 SUPERFAMILY SSF103196 5 129 1.48E-34 T 12-10-2018 UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Pfam PF13606 Ankyrin repeat 239 263 1.1E-4 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SUPERFAMILY SSF48403 123 281 8.65E-34 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Pfam PF12680 SnoaL-like domain 10 122 3.7E-7 T 12-10-2018 IPR037401 SnoaL-like domain UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Gene3D G3DSA:3.10.450.50 1 138 3.6E-22 T 12-10-2018 UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SMART SM00248 238 267 0.1 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SMART SM00248 171 200 0.016 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SMART SM00248 204 233 8.1E-5 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Gene3D G3DSA:1.25.40.20 139 286 1.0E-37 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 Pfam PF12796 Ankyrin repeats (3 copies) 143 229 1.1E-12 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain UA74_07520 4d31c86377bf7b3f9841f9cbf8e8a01b 297 SUPERFAMILY SSF54427 7 135 1.87E-19 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_10060 d70ea0102fd20281f85ae54ee6eecdd1 391 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 UA74_10060 d70ea0102fd20281f85ae54ee6eecdd1 391 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 7 267 7.3E-42 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 UA74_10060 d70ea0102fd20281f85ae54ee6eecdd1 391 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 270 1.5E-64 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 UA74_10060 d70ea0102fd20281f85ae54ee6eecdd1 391 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 276 15.64 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 UA74_29345 7707db7cf23a865d00c51cfdf374a13f 392 Gene3D G3DSA:3.40.640.10 8 392 2.4E-123 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_29345 7707db7cf23a865d00c51cfdf374a13f 392 SUPERFAMILY SSF53383 14 389 2.24E-96 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_29345 7707db7cf23a865d00c51cfdf374a13f 392 Pfam PF00155 Aminotransferase class I and II 37 384 1.6E-57 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_29345 7707db7cf23a865d00c51cfdf374a13f 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UA74_01780 ef6d45bc18cbf8ddae029b6bd0f14158 305 SUPERFAMILY SSF161098 62 291 6.41E-57 T 12-10-2018 IPR035906 MetI-like superfamily UA74_01780 ef6d45bc18cbf8ddae029b6bd0f14158 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 295 8.0E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_01780 ef6d45bc18cbf8ddae029b6bd0f14158 305 Gene3D G3DSA:1.10.3720.10 59 303 5.1E-67 T 12-10-2018 IPR035906 MetI-like superfamily UA74_06715 e8cd3fd2465b8e3d4f247f9fb9c58c10 378 SUPERFAMILY SSF103481 41 134 3.53E-12 T 12-10-2018 UA74_06715 e8cd3fd2465b8e3d4f247f9fb9c58c10 378 Pfam PF00892 EamA-like transporter family 141 282 2.5E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_06715 e8cd3fd2465b8e3d4f247f9fb9c58c10 378 Pfam PF00892 EamA-like transporter family 8 130 6.9E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_06715 e8cd3fd2465b8e3d4f247f9fb9c58c10 378 SUPERFAMILY SSF103481 187 282 4.18E-9 T 12-10-2018 UA74_25150 3792344045dc6bf9b19e1e61e165567b 1317 SUPERFAMILY SSF53756 565 808 1.88E-13 T 12-10-2018 UA74_25150 3792344045dc6bf9b19e1e61e165567b 1317 SUPERFAMILY SSF53335 1037 1279 5.34E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_25150 3792344045dc6bf9b19e1e61e165567b 1317 Gene3D G3DSA:3.40.50.2000 606 794 4.0E-14 T 12-10-2018 UA74_25150 3792344045dc6bf9b19e1e61e165567b 1317 Pfam PF05050 Methyltransferase FkbM domain 1095 1278 2.4E-8 T 12-10-2018 IPR006342 Methyltransferase FkbM UA74_25150 3792344045dc6bf9b19e1e61e165567b 1317 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 1092 1253 1.4E-13 T 12-10-2018 IPR006342 Methyltransferase FkbM UA74_25150 3792344045dc6bf9b19e1e61e165567b 1317 Gene3D G3DSA:3.40.50.150 1082 1284 1.5E-21 T 12-10-2018 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 577 7.1E-273 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 SUPERFAMILY SSF100920 358 514 1.11E-57 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:3.30.420.40 5 350 3.9E-146 T 12-10-2018 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 Pfam PF00012 Hsp70 protein 79 577 2.7E-212 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 Pfam PF00012 Hsp70 protein 4 78 2.4E-29 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:3.30.420.40 162 339 3.9E-146 T 12-10-2018 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:3.90.640.10 200 288 3.9E-146 T 12-10-2018 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:1.20.1270.10 481 580 6.5E-31 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 SUPERFAMILY SSF100934 508 565 1.73E-5 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 443 459 3.2E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.2E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 362 381 3.2E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 174 184 3.2E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 339 359 3.2E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 114 134 3.2E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 307 323 3.2E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.2E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.2E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 SUPERFAMILY SSF53067 4 160 3.08E-58 T 12-10-2018 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 SUPERFAMILY SSF53067 162 356 2.22E-61 T 12-10-2018 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 618 35.838 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 UA74_29710 dda1ed766d29fac4b68b39e26bfc2230 624 Gene3D G3DSA:2.60.34.10 351 478 2.7E-57 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 UA74_09835 7028a52056747f7e13f87d031dea0240 545 Pfam PF00890 FAD binding domain 10 396 9.8E-84 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_09835 7028a52056747f7e13f87d031dea0240 545 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 374 381 5.3E-7 T 12-10-2018 UA74_09835 7028a52056747f7e13f87d031dea0240 545 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 5.3E-7 T 12-10-2018 UA74_09835 7028a52056747f7e13f87d031dea0240 545 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 381 5.8E-10 T 12-10-2018 UA74_09835 7028a52056747f7e13f87d031dea0240 545 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 5.8E-10 T 12-10-2018 UA74_09835 7028a52056747f7e13f87d031dea0240 545 SUPERFAMILY SSF56425 236 356 3.44E-34 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_09835 7028a52056747f7e13f87d031dea0240 545 Gene3D G3DSA:1.20.58.100 426 527 1.0E-11 T 12-10-2018 UA74_09835 7028a52056747f7e13f87d031dea0240 545 SUPERFAMILY SSF51905 3 412 2.97E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09835 7028a52056747f7e13f87d031dea0240 545 Gene3D G3DSA:3.90.700.10 246 351 4.6E-134 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_09835 7028a52056747f7e13f87d031dea0240 545 Pfam PF02910 Fumarate reductase flavoprotein C-term 485 523 2.7E-9 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_09835 7028a52056747f7e13f87d031dea0240 545 SUPERFAMILY SSF46977 440 531 5.63E-20 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_09835 7028a52056747f7e13f87d031dea0240 545 Gene3D G3DSA:3.50.50.60 10 406 4.6E-134 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09835 7028a52056747f7e13f87d031dea0240 545 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 9 512 2.9E-154 T 12-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 UA74_05965 7e806f9b117f142335184b93e4c9bd46 290 SMART SM00530 13 68 3.1E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_05965 7e806f9b117f142335184b93e4c9bd46 290 Gene3D G3DSA:1.10.260.40 4 68 1.5E-11 T 12-10-2018 UA74_05965 7e806f9b117f142335184b93e4c9bd46 290 SUPERFAMILY SSF47413 8 64 2.56E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_05965 7e806f9b117f142335184b93e4c9bd46 290 Pfam PF13560 Helix-turn-helix domain 9 70 1.1E-14 T 12-10-2018 UA74_26140 d6544c658df5f4c62b11c0908c23e3e2 163 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 92 4.7E-10 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_26140 d6544c658df5f4c62b11c0908c23e3e2 163 Gene3D G3DSA:2.30.110.10 1 116 4.2E-15 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_26140 d6544c658df5f4c62b11c0908c23e3e2 163 SUPERFAMILY SSF50475 10 106 7.18E-15 T 12-10-2018 UA74_26740 283d25a7fd8251a5cb3d39e66f43d2cf 507 SUPERFAMILY SSF52540 12 237 1.98E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26740 283d25a7fd8251a5cb3d39e66f43d2cf 507 Gene3D G3DSA:3.40.50.300 262 502 8.4E-46 T 12-10-2018 UA74_26740 283d25a7fd8251a5cb3d39e66f43d2cf 507 Pfam PF00005 ABC transporter 279 432 8.1E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_26740 283d25a7fd8251a5cb3d39e66f43d2cf 507 Pfam PF00005 ABC transporter 29 179 7.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_26740 283d25a7fd8251a5cb3d39e66f43d2cf 507 SMART SM00382 287 481 5.7E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_26740 283d25a7fd8251a5cb3d39e66f43d2cf 507 SMART SM00382 38 221 6.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_26740 283d25a7fd8251a5cb3d39e66f43d2cf 507 Gene3D G3DSA:3.40.50.300 2 254 1.8E-56 T 12-10-2018 UA74_26740 283d25a7fd8251a5cb3d39e66f43d2cf 507 SUPERFAMILY SSF52540 277 491 2.62E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26740 283d25a7fd8251a5cb3d39e66f43d2cf 507 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_10235 69bcf2442ba06d7b387254f8bc895287 425 Pfam PF01420 Type I restriction modification DNA specificity domain 32 170 1.2E-5 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 UA74_10235 69bcf2442ba06d7b387254f8bc895287 425 SUPERFAMILY SSF116734 18 183 1.64E-24 T 12-10-2018 UA74_10235 69bcf2442ba06d7b387254f8bc895287 425 SUPERFAMILY SSF116734 219 412 2.94E-19 T 12-10-2018 UA74_10235 69bcf2442ba06d7b387254f8bc895287 425 Gene3D G3DSA:3.90.220.20 12 197 2.3E-25 T 12-10-2018 UA74_10235 69bcf2442ba06d7b387254f8bc895287 425 Gene3D G3DSA:3.90.220.20 214 409 3.5E-17 T 12-10-2018 UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.5E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 Gene3D G3DSA:3.40.50.720 1 260 8.5E-60 T 12-10-2018 UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 194 2.5E-4 T 12-10-2018 UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 Pfam PF00106 short chain dehydrogenase 9 199 2.9E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 SUPERFAMILY SSF51735 3 257 1.59E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 PIRSF PIRSF000126 1 267 3.7E-65 T 12-10-2018 UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 3.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 3.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16845 c5e9c327f0e14fc88036194dc5faae1c 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13855 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 Gene3D G3DSA:3.40.50.720 5 143 4.5E-34 T 12-10-2018 UA74_13855 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 Gene3D G3DSA:3.30.360.10 144 385 2.6E-64 T 12-10-2018 UA74_13855 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 SUPERFAMILY SSF55347 149 340 2.62E-29 T 12-10-2018 UA74_13855 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 53 141 3.3E-8 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_13855 55b2ad7e57e68e3ea9c6aca8a28e0b4d 386 SUPERFAMILY SSF51735 52 176 1.49E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_03700 714fbbd6330c083278fbb1b8c65d28a8 234 Gene3D G3DSA:1.20.120.530 79 221 1.5E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_03700 714fbbd6330c083278fbb1b8c65d28a8 234 SMART SM00895 86 210 1.2E-18 T 12-10-2018 IPR011711 GntR, C-terminal UA74_03700 714fbbd6330c083278fbb1b8c65d28a8 234 SUPERFAMILY SSF48008 82 217 2.3E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_03700 714fbbd6330c083278fbb1b8c65d28a8 234 Gene3D G3DSA:1.10.10.10 2 77 5.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_03700 714fbbd6330c083278fbb1b8c65d28a8 234 SMART SM00345 18 76 8.2E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_03700 714fbbd6330c083278fbb1b8c65d28a8 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 76 1.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_03700 714fbbd6330c083278fbb1b8c65d28a8 234 SUPERFAMILY SSF46785 16 100 2.02E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_03700 714fbbd6330c083278fbb1b8c65d28a8 234 Pfam PF07729 FCD domain 86 208 4.8E-24 T 12-10-2018 IPR011711 GntR, C-terminal UA74_25735 9bc3687f271725d6dd6b5475a1274259 174 SUPERFAMILY SSF51161 2 152 2.5E-41 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily UA74_25735 9bc3687f271725d6dd6b5475a1274259 174 Gene3D G3DSA:2.160.10.10 2 169 2.6E-48 T 12-10-2018 UA74_25735 9bc3687f271725d6dd6b5475a1274259 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 45 2.2E-6 T 12-10-2018 IPR001451 Hexapeptide repeat UA74_25735 9bc3687f271725d6dd6b5475a1274259 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 104 3.4E-5 T 12-10-2018 IPR001451 Hexapeptide repeat UA74_27660 f15bbba08793fe61baebc38baf3e1d90 201 Pfam PF00551 Formyl transferase 4 183 3.3E-51 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_27660 f15bbba08793fe61baebc38baf3e1d90 201 SUPERFAMILY SSF53328 4 199 2.88E-58 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_27660 f15bbba08793fe61baebc38baf3e1d90 201 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 135 158 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_27660 f15bbba08793fe61baebc38baf3e1d90 201 Gene3D G3DSA:3.40.50.170 1 201 4.6E-77 T 12-10-2018 UA74_27660 f15bbba08793fe61baebc38baf3e1d90 201 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 4 189 28.892 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 UA74_27660 f15bbba08793fe61baebc38baf3e1d90 201 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 4 190 2.8E-66 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 SMART SM00344 1 108 4.4E-18 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 Gene3D G3DSA:1.10.10.10 1 48 6.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 Pfam PF13404 AsnC-type helix-turn-helix domain 1 41 9.1E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 Pfam PF01037 Lrp/AsnC ligand binding domain 69 137 4.2E-13 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 Gene3D G3DSA:3.30.70.920 50 141 4.8E-14 T 12-10-2018 UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 SUPERFAMILY SSF54909 63 137 8.85E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 SUPERFAMILY SSF46785 1 55 1.8E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.4E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.4E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_10315 6c6c33a96ab3acc729b8cec3b294a95c 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.4E-12 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 Gene3D G3DSA:3.30.70.920 58 138 1.3E-19 T 12-10-2018 UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 SUPERFAMILY SSF46785 4 71 8.83E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 SMART SM00344 5 112 2.1E-37 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 SMART SM00418 3 89 0.0035 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 Gene3D G3DSA:1.10.10.10 6 57 7.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 SUPERFAMILY SSF54909 66 144 1.74E-13 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 3.0E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 3.0E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 3.0E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 2.0E-18 T 12-10-2018 UA74_12965 11fbafd5e7b9eb1ab6532a500dc65731 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 141 7.8E-14 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_01650 381c556d4c07fbedcb0c9c5c2d684925 294 Gene3D G3DSA:1.10.340.30 21 133 7.6E-68 T 12-10-2018 UA74_01650 381c556d4c07fbedcb0c9c5c2d684925 294 Gene3D G3DSA:1.10.1670.10 10 212 7.6E-68 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 UA74_01650 381c556d4c07fbedcb0c9c5c2d684925 294 Pfam PF00633 Helix-hairpin-helix motif 101 129 7.8E-7 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 UA74_01650 381c556d4c07fbedcb0c9c5c2d684925 294 SUPERFAMILY SSF48150 9 219 3.3E-62 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_01650 381c556d4c07fbedcb0c9c5c2d684925 294 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 153 9.2E-16 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_01650 381c556d4c07fbedcb0c9c5c2d684925 294 SMART SM00478 40 192 2.3E-41 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_14840 fa7b791a5ee4a52f1962c85396b5a370 315 Pfam PF12833 Helix-turn-helix domain 213 290 1.1E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_14840 fa7b791a5ee4a52f1962c85396b5a370 315 SUPERFAMILY SSF46689 190 241 6.81E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14840 fa7b791a5ee4a52f1962c85396b5a370 315 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 244 286 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UA74_14840 fa7b791a5ee4a52f1962c85396b5a370 315 SUPERFAMILY SSF46689 243 293 4.93E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14840 fa7b791a5ee4a52f1962c85396b5a370 315 Gene3D G3DSA:1.10.10.60 188 296 1.3E-22 T 12-10-2018 UA74_14840 fa7b791a5ee4a52f1962c85396b5a370 315 SMART SM00342 207 290 7.3E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_14840 fa7b791a5ee4a52f1962c85396b5a370 315 Pfam PF12852 Cupin 2 175 4.1E-42 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain UA74_04810 ae7f03f129c2eb95ebbd6d35f2bfe116 430 Pfam PF00675 Insulinase (Peptidase family M16) 17 131 4.0E-18 T 12-10-2018 IPR011765 Peptidase M16, N-terminal UA74_04810 ae7f03f129c2eb95ebbd6d35f2bfe116 430 Gene3D G3DSA:3.30.830.10 227 423 3.7E-31 T 12-10-2018 UA74_04810 ae7f03f129c2eb95ebbd6d35f2bfe116 430 Pfam PF05193 Peptidase M16 inactive domain 173 353 6.8E-18 T 12-10-2018 IPR007863 Peptidase M16, C-terminal UA74_04810 ae7f03f129c2eb95ebbd6d35f2bfe116 430 Gene3D G3DSA:3.30.830.10 2 223 1.6E-58 T 12-10-2018 UA74_04810 ae7f03f129c2eb95ebbd6d35f2bfe116 430 SUPERFAMILY SSF63411 5 220 1.25E-48 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_04810 ae7f03f129c2eb95ebbd6d35f2bfe116 430 SUPERFAMILY SSF63411 231 421 3.67E-18 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_14855 d600a7deb97dd608bbe84f40ad3495ae 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 3.2E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14855 d600a7deb97dd608bbe84f40ad3495ae 204 SUPERFAMILY SSF46689 5 83 1.55E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14855 d600a7deb97dd608bbe84f40ad3495ae 204 Gene3D G3DSA:1.10.357.10 3 203 5.3E-43 T 12-10-2018 UA74_14855 d600a7deb97dd608bbe84f40ad3495ae 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 7.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14855 d600a7deb97dd608bbe84f40ad3495ae 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 7.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14855 d600a7deb97dd608bbe84f40ad3495ae 204 SUPERFAMILY SSF48498 83 199 1.85E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 SUPERFAMILY SSF52518 923 1134 6.57E-43 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Gene3D G3DSA:3.40.50.12470 894 1151 1.2E-157 T 12-10-2018 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF02779 Transketolase, pyrimidine binding domain 935 1127 1.4E-53 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 SUPERFAMILY SSF52777 162 398 4.89E-54 T 12-10-2018 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Gene3D G3DSA:3.30.559.10 147 405 1.1E-52 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 432 1275 5.0E-303 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1133 1276 5.1E-45 T 12-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 164 398 2.4E-54 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Gene3D G3DSA:1.10.287.1150 427 508 1.2E-28 T 12-10-2018 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Gene3D G3DSA:3.40.50.11610 1071 1274 1.2E-157 T 12-10-2018 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 SUPERFAMILY SSF52518 463 872 1.12E-83 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 SMART SM00861 935 1128 4.0E-48 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF00676 Dehydrogenase E1 component 550 873 7.2E-58 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 10 43 3.1E-12 T 12-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UA74_26275 fc37f0e27407243634d98f4909da5a30 1277 Gene3D G3DSA:3.40.50.970 509 874 1.0E-143 T 12-10-2018 UA74_08145 8568993f37697d92a4fa46968a5a581c 308 Pfam PF00005 ABC transporter 22 164 2.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_08145 8568993f37697d92a4fa46968a5a581c 308 SMART SM00382 30 213 2.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_08145 8568993f37697d92a4fa46968a5a581c 308 Gene3D G3DSA:3.40.50.300 4 236 8.2E-68 T 12-10-2018 UA74_08145 8568993f37697d92a4fa46968a5a581c 308 SUPERFAMILY SSF52540 6 227 1.33E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08145 8568993f37697d92a4fa46968a5a581c 308 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_12705 8d0071865c8830f924c3b044d73d2059 402 Gene3D G3DSA:3.90.180.10 52 400 1.8E-89 T 12-10-2018 UA74_12705 8d0071865c8830f924c3b044d73d2059 402 Pfam PF00107 Zinc-binding dehydrogenase 232 359 1.0E-22 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_12705 8d0071865c8830f924c3b044d73d2059 402 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 79 190 4.0E-20 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_12705 8d0071865c8830f924c3b044d73d2059 402 SMART SM00829 62 396 2.9E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_12705 8d0071865c8830f924c3b044d73d2059 402 SUPERFAMILY SSF51735 194 363 7.14E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12705 8d0071865c8830f924c3b044d73d2059 402 SUPERFAMILY SSF50129 48 234 3.65E-42 T 12-10-2018 IPR011032 GroES-like superfamily UA74_09170 2395a1e6bed467bf10d5fb7203ea551c 507 SMART SM00490 320 401 1.3E-31 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_09170 2395a1e6bed467bf10d5fb7203ea551c 507 Gene3D G3DSA:3.40.50.300 293 445 7.5E-45 T 12-10-2018 UA74_09170 2395a1e6bed467bf10d5fb7203ea551c 507 Gene3D G3DSA:3.40.50.300 40 274 1.9E-70 T 12-10-2018 UA74_09170 2395a1e6bed467bf10d5fb7203ea551c 507 SUPERFAMILY SSF52540 139 416 1.6E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_09170 2395a1e6bed467bf10d5fb7203ea551c 507 SMART SM00487 86 286 5.0E-50 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_09170 2395a1e6bed467bf10d5fb7203ea551c 507 Pfam PF00271 Helicase conserved C-terminal domain 304 401 1.9E-25 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_09170 2395a1e6bed467bf10d5fb7203ea551c 507 Pfam PF00270 DEAD/DEAH box helicase 91 257 1.1E-40 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_10710 338fe5ebcaac43238da62d046df06ace 937 SMART SM00939 360 587 2.3E-7 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_10710 338fe5ebcaac43238da62d046df06ace 937 SUPERFAMILY SSF52540 632 859 9.87E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10710 338fe5ebcaac43238da62d046df06ace 937 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 56 319 5.4E-17 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_10710 338fe5ebcaac43238da62d046df06ace 937 Gene3D G3DSA:2.60.120.260 429 583 1.4E-12 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_10710 338fe5ebcaac43238da62d046df06ace 937 SMART SM00382 664 852 4.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_10710 338fe5ebcaac43238da62d046df06ace 937 SUPERFAMILY SSF49785 419 589 1.25E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_10710 338fe5ebcaac43238da62d046df06ace 937 Gene3D G3DSA:3.40.50.300 634 863 3.8E-58 T 12-10-2018 UA74_10710 338fe5ebcaac43238da62d046df06ace 937 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 451 575 4.3E-9 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_10710 338fe5ebcaac43238da62d046df06ace 937 ProSitePatterns PS00211 ABC transporters family signature. 768 782 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_10710 338fe5ebcaac43238da62d046df06ace 937 SUPERFAMILY SSF53474 12 368 1.06E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_10710 338fe5ebcaac43238da62d046df06ace 937 Pfam PF00005 ABC transporter 656 796 2.3E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_23750 18114757b86259716f853c2f06613488 704 Gene3D G3DSA:3.40.50.720 331 519 5.8E-61 T 12-10-2018 UA74_23750 18114757b86259716f853c2f06613488 704 SUPERFAMILY SSF51735 332 516 6.18E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_23750 18114757b86259716f853c2f06613488 704 Pfam PF00378 Enoyl-CoA hydratase/isomerase 51 233 6.7E-25 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UA74_23750 18114757b86259716f853c2f06613488 704 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 335 514 2.1E-56 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UA74_23750 18114757b86259716f853c2f06613488 704 SUPERFAMILY SSF48179 629 695 9.35E-11 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_23750 18114757b86259716f853c2f06613488 704 SUPERFAMILY SSF48179 516 620 9.35E-15 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_23750 18114757b86259716f853c2f06613488 704 SUPERFAMILY SSF52096 32 312 7.24E-39 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_23750 18114757b86259716f853c2f06613488 704 Gene3D G3DSA:1.10.1040.50 520 699 3.2E-32 T 12-10-2018 UA74_23750 18114757b86259716f853c2f06613488 704 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 518 599 2.3E-11 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UA74_23750 18114757b86259716f853c2f06613488 704 Gene3D G3DSA:3.90.226.10 24 327 2.1E-52 T 12-10-2018 UA74_10775 05c6fbf11473b4c3b34bd419e021b97f 381 Pfam PF13439 Glycosyltransferase Family 4 14 173 1.8E-24 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_10775 05c6fbf11473b4c3b34bd419e021b97f 381 Pfam PF13692 Glycosyl transferases group 1 190 330 1.8E-29 T 12-10-2018 UA74_10775 05c6fbf11473b4c3b34bd419e021b97f 381 Gene3D G3DSA:3.40.50.2000 12 361 1.4E-117 T 12-10-2018 UA74_10775 05c6fbf11473b4c3b34bd419e021b97f 381 Gene3D G3DSA:3.40.50.2000 171 348 1.4E-117 T 12-10-2018 UA74_10775 05c6fbf11473b4c3b34bd419e021b97f 381 SUPERFAMILY SSF53756 3 365 1.53E-72 T 12-10-2018 UA74_04865 ac2ac8504fdd803971789f57b7c210ed 438 Pfam PF03109 ABC1 family 112 227 1.8E-31 T 12-10-2018 IPR004147 UbiB domain UA74_04865 ac2ac8504fdd803971789f57b7c210ed 438 Gene3D G3DSA:1.10.510.10 127 318 1.2E-6 T 12-10-2018 UA74_04865 ac2ac8504fdd803971789f57b7c210ed 438 SUPERFAMILY SSF56112 95 307 1.14E-27 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_24675 3cc631812e2a07774556e82824add5b1 368 Gene3D G3DSA:1.10.600.10 3 368 2.7E-110 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_24675 3cc631812e2a07774556e82824add5b1 368 SUPERFAMILY SSF48576 24 367 3.84E-72 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_24675 3cc631812e2a07774556e82824add5b1 368 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 98 112 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site UA74_24675 3cc631812e2a07774556e82824add5b1 368 Pfam PF00348 Polyprenyl synthetase 50 293 2.2E-44 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 UA74_23775 9b2d6a1929828631735cdebcc45f6482 295 SUPERFAMILY SSF51735 2 294 1.81E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_23775 9b2d6a1929828631735cdebcc45f6482 295 Gene3D G3DSA:3.40.50.720 1 295 1.1E-46 T 12-10-2018 UA74_23775 9b2d6a1929828631735cdebcc45f6482 295 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 238 2.6E-21 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 Gene3D G3DSA:1.20.58.180 203 283 3.6E-27 T 12-10-2018 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 305 1006 20.326 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 279 49.921 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 307 1004 6.3E-152 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 308 874 2.7E-168 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 Gene3D G3DSA:3.30.930.10 1 202 3.2E-99 T 12-10-2018 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 SUPERFAMILY SSF109604 655 806 1.57E-7 T 12-10-2018 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 53 68 3.1E-57 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 154 169 3.1E-57 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 239 255 3.1E-57 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 105 129 3.1E-57 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 74 94 3.1E-57 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 131 151 3.1E-57 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 1 278 2.8E-127 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 284 5.8E-121 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UA74_18970 03945843eff1c948d114e54e1de8891b 1013 SUPERFAMILY SSF55681 2 278 2.98E-109 T 12-10-2018 UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 146 219 3.8E-13 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 ProSitePatterns PS01242 Zinc finger FPG-type signature. 247 271 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 SUPERFAMILY SSF57716 233 271 1.08E-11 T 12-10-2018 UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 85 3.3E-15 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 SMART SM00898 2 125 1.2E-21 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 Gene3D G3DSA:3.20.190.10 2 108 2.1E-14 T 12-10-2018 IPR035937 MutM-like, N-terminal UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 Gene3D G3DSA:1.10.8.50 135 272 9.5E-30 T 12-10-2018 UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 SUPERFAMILY SSF46946 139 219 1.83E-16 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 SUPERFAMILY SSF81624 2 142 7.72E-21 T 12-10-2018 IPR035937 MutM-like, N-terminal UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 SMART SM01232 139 226 6.6E-18 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UA74_00385 15199fa35fb2d01aab8227ee286ceacb 287 Pfam PF06827 Zinc finger found in FPG and IleRS 244 271 7.5E-8 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 UA74_24575 b200903da4c6971d2a271b05d4e3b8b7 272 SUPERFAMILY SSF53335 54 181 1.07E-15 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_24575 b200903da4c6971d2a271b05d4e3b8b7 272 Gene3D G3DSA:3.40.50.150 30 196 2.8E-15 T 12-10-2018 UA74_24575 b200903da4c6971d2a271b05d4e3b8b7 272 Pfam PF13489 Methyltransferase domain 49 171 1.3E-6 T 12-10-2018 UA74_30240 6c054422d3cfa5c0867729be12cbc7e9 164 Pfam PF08281 Sigma-70, region 4 80 132 1.3E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_30240 6c054422d3cfa5c0867729be12cbc7e9 164 SUPERFAMILY SSF88946 2 63 5.49E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_30240 6c054422d3cfa5c0867729be12cbc7e9 164 SUPERFAMILY SSF88659 72 137 1.5E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_30240 6c054422d3cfa5c0867729be12cbc7e9 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 135 4.0E-26 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_30240 6c054422d3cfa5c0867729be12cbc7e9 164 Gene3D G3DSA:1.10.1740.10 1 54 1.2E-17 T 12-10-2018 UA74_30240 6c054422d3cfa5c0867729be12cbc7e9 164 Pfam PF04542 Sigma-70 region 2 2 52 1.3E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_30240 6c054422d3cfa5c0867729be12cbc7e9 164 Gene3D G3DSA:1.10.10.10 60 139 5.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14845 cb0a92006d5e6c269a63ebfe59fb6721 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 14 165 3.0E-20 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UA74_14845 cb0a92006d5e6c269a63ebfe59fb6721 302 Gene3D G3DSA:3.40.50.720 2 169 1.1E-41 T 12-10-2018 UA74_14845 cb0a92006d5e6c269a63ebfe59fb6721 302 SUPERFAMILY SSF51735 14 164 2.35E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14845 cb0a92006d5e6c269a63ebfe59fb6721 302 Gene3D G3DSA:1.10.1040.10 170 301 7.5E-43 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_14845 cb0a92006d5e6c269a63ebfe59fb6721 302 PIRSF PIRSF000103 6 302 1.0E-41 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_14845 cb0a92006d5e6c269a63ebfe59fb6721 302 SUPERFAMILY SSF48179 183 297 1.25E-5 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_04720 fa5e7edc389ac976fc0199c4fdbb7ac0 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 3.2E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_04720 fa5e7edc389ac976fc0199c4fdbb7ac0 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_04720 fa5e7edc389ac976fc0199c4fdbb7ac0 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_04720 fa5e7edc389ac976fc0199c4fdbb7ac0 210 SUPERFAMILY SSF48498 92 204 4.6E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_04720 fa5e7edc389ac976fc0199c4fdbb7ac0 210 SUPERFAMILY SSF46689 13 92 3.94E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_04720 fa5e7edc389ac976fc0199c4fdbb7ac0 210 Gene3D G3DSA:1.10.357.10 10 209 1.2E-48 T 12-10-2018 UA74_03860 8dd461a5ec876ffbd4473eb445d6c654 385 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 197 211 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_03860 8dd461a5ec876ffbd4473eb445d6c654 385 Gene3D G3DSA:3.90.1150.10 256 385 2.2E-50 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_03860 8dd461a5ec876ffbd4473eb445d6c654 385 PIRSF PIRSF001434 2 385 2.2E-144 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_03860 8dd461a5ec876ffbd4473eb445d6c654 385 SUPERFAMILY SSF53383 14 384 1.24E-126 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_03860 8dd461a5ec876ffbd4473eb445d6c654 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 13 384 1.7E-147 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_03860 8dd461a5ec876ffbd4473eb445d6c654 385 Gene3D G3DSA:3.40.640.10 2 255 1.1E-105 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_18215 a621cffa0366054542a50aaf6bbc91be 371 SUPERFAMILY SSF52540 8 208 1.78E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18215 a621cffa0366054542a50aaf6bbc91be 371 Gene3D G3DSA:3.40.50.300 7 200 2.2E-51 T 12-10-2018 UA74_18215 a621cffa0366054542a50aaf6bbc91be 371 SMART SM00833 259 350 1.4E-16 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_18215 a621cffa0366054542a50aaf6bbc91be 371 SUPERFAMILY SSF90002 260 350 7.19E-18 T 12-10-2018 UA74_18215 a621cffa0366054542a50aaf6bbc91be 371 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 10 184 4.3E-43 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain UA74_18215 a621cffa0366054542a50aaf6bbc91be 371 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 260 350 3.7E-23 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_18215 a621cffa0366054542a50aaf6bbc91be 371 Gene3D G3DSA:3.30.1220.10 244 351 2.1E-11 T 12-10-2018 IPR036627 CobW-like, C-terminal domain superfamily UA74_02525 f08f75c9900a733227cafc5dcc38e322 303 Gene3D G3DSA:1.20.1260.10 39 303 2.1E-96 T 12-10-2018 IPR012347 Ferritin-like UA74_02525 f08f75c9900a733227cafc5dcc38e322 303 PIRSF PIRSF037834 37 303 8.1E-87 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UA74_02525 f08f75c9900a733227cafc5dcc38e322 303 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 52 303 4.4E-70 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UA74_02525 f08f75c9900a733227cafc5dcc38e322 303 SUPERFAMILY SSF47240 44 297 2.3E-60 T 12-10-2018 IPR009078 Ferritin-like superfamily UA74_02525 f08f75c9900a733227cafc5dcc38e322 303 Pfam PF05138 Phenylacetic acid catabolic protein 42 303 1.8E-75 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UA74_08855 b69f426dbbb8ce1cddfe9693f5bdfea9 251 SUPERFAMILY SSF53098 27 216 2.58E-58 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_08855 b69f426dbbb8ce1cddfe9693f5bdfea9 251 Gene3D G3DSA:3.30.420.10 13 226 4.2E-63 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_08855 b69f426dbbb8ce1cddfe9693f5bdfea9 251 Pfam PF01351 Ribonuclease HII 34 213 5.0E-36 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain UA74_08855 b69f426dbbb8ce1cddfe9693f5bdfea9 251 Hamap MF_00052_B Ribonuclease HII [rnhB]. 32 213 34.573 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 UA74_24935 2bf9f852d2adf2fa52d64bfeda34068e 356 Pfam PF00591 Glycosyl transferase family, a/b domain 83 336 3.7E-78 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_24935 2bf9f852d2adf2fa52d64bfeda34068e 356 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 14 346 33.586 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UA74_24935 2bf9f852d2adf2fa52d64bfeda34068e 356 SUPERFAMILY SSF47648 12 79 8.77E-20 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_24935 2bf9f852d2adf2fa52d64bfeda34068e 356 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 17 345 3.3E-108 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UA74_24935 2bf9f852d2adf2fa52d64bfeda34068e 356 Gene3D G3DSA:3.40.1030.10 82 353 5.3E-91 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_24935 2bf9f852d2adf2fa52d64bfeda34068e 356 SUPERFAMILY SSF52418 81 343 6.8E-76 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_24935 2bf9f852d2adf2fa52d64bfeda34068e 356 Gene3D G3DSA:1.20.970.10 10 75 2.4E-31 T 12-10-2018 UA74_24935 2bf9f852d2adf2fa52d64bfeda34068e 356 Pfam PF02885 Glycosyl transferase family, helical bundle domain 15 75 1.2E-19 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_25925 5d20549ae20dfa9706cb733fc05c0952 89 Pfam PF04149 Domain of unknown function (DUF397) 30 81 5.9E-12 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 SUPERFAMILY SSF46894 136 207 1.63E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 SMART SM00421 147 204 7.4E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 1.8E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 SMART SM00448 3 116 3.4E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 Gene3D G3DSA:3.40.50.12740 3 209 1.3E-62 T 12-10-2018 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 SUPERFAMILY SSF52172 3 133 7.26E-32 T 12-10-2018 IPR011006 CheY-like superfamily UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 Pfam PF00072 Response regulator receiver domain 5 117 4.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_00570 b43db1b688493b186f2a5ec5326ff270 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05420 56d03dae79e4993afc90c6e8c5eee5d8 299 Gene3D G3DSA:3.40.50.300 2 227 2.7E-61 T 12-10-2018 UA74_05420 56d03dae79e4993afc90c6e8c5eee5d8 299 SUPERFAMILY SSF52540 8 223 4.49E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_05420 56d03dae79e4993afc90c6e8c5eee5d8 299 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_05420 56d03dae79e4993afc90c6e8c5eee5d8 299 SMART SM00382 34 216 2.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_05420 56d03dae79e4993afc90c6e8c5eee5d8 299 Pfam PF00005 ABC transporter 26 162 3.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 3.3E-63 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 3.3E-63 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 3.3E-63 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 3.3E-63 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 3.3E-63 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.3E-63 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.3E-63 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 3.3E-63 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 3.3E-63 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PIRSF PIRSF000350 1 462 7.8E-87 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 SUPERFAMILY SSF51905 1 336 4.86E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 Gene3D G3DSA:3.30.390.30 346 466 3.2E-44 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 Gene3D G3DSA:3.50.50.60 5 332 7.3E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 SUPERFAMILY SSF55424 343 465 3.78E-37 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 2.6E-35 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 2.6E-35 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 2.6E-35 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.6E-35 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 2.6E-35 T 12-10-2018 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 Gene3D G3DSA:3.50.50.60 150 270 7.3E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 1.2E-33 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 466 1.2E-164 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 UA74_06120 cbf8af0035d5683e7178a265b38b8f69 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 327 7.7E-66 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_13110 9eaad1f388beddedc0269d7d74c85dda 185 Pfam PF04264 YceI-like domain 16 181 1.2E-44 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like UA74_13110 9eaad1f388beddedc0269d7d74c85dda 185 SUPERFAMILY SSF101874 14 182 7.85E-54 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily UA74_13110 9eaad1f388beddedc0269d7d74c85dda 185 Gene3D G3DSA:2.40.128.110 15 184 1.4E-51 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily UA74_13110 9eaad1f388beddedc0269d7d74c85dda 185 SMART SM00867 15 182 1.2E-70 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 TIGRFAM TIGR01391 dnaG: DNA primase 5 427 2.9E-109 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF01807 CHC2 zinc finger 7 100 1.5E-32 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 SMART SM00766 487 616 6.5E-18 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 Gene3D G3DSA:3.90.580.10 1 101 1.6E-35 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 Gene3D G3DSA:3.90.980.10 111 243 1.6E-33 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF13662 Toprim domain 263 337 1.1E-16 T 12-10-2018 IPR006171 TOPRIM domain UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF08278 DNA primase DnaG DnaB-binding 488 615 2.0E-22 T 12-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 SUPERFAMILY SSF57783 4 100 5.61E-32 T 12-10-2018 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF10410 DnaB-helicase binding domain of primase 381 434 1.3E-16 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 Gene3D G3DSA:3.40.1360.10 244 378 1.7E-35 T 12-10-2018 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 SUPERFAMILY SSF56731 117 434 4.18E-89 T 12-10-2018 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 SMART SM00400 37 91 5.7E-34 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 SMART SM00493 262 344 4.6E-10 T 12-10-2018 IPR006171 TOPRIM domain UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 PIRSF PIRSF002811 2 627 2.3E-140 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 Hamap MF_00974 DNA primase [dnaG]. 4 621 25.794 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 UA74_24350 b6fd22fe15066a2fe807d1c604e28272 638 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 1.1E-34 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal UA74_25155 b0ffdc3ebf9430384b0161a65e1216f5 447 Gene3D G3DSA:3.30.590.10 109 445 3.1E-121 T 12-10-2018 UA74_25155 b0ffdc3ebf9430384b0161a65e1216f5 447 SMART SM01230 106 357 1.1E-126 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25155 b0ffdc3ebf9430384b0161a65e1216f5 447 SUPERFAMILY SSF54368 8 105 1.44E-28 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25155 b0ffdc3ebf9430384b0161a65e1216f5 447 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 1.1E-24 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UA74_25155 b0ffdc3ebf9430384b0161a65e1216f5 447 Gene3D G3DSA:3.10.20.70 2 108 1.7E-33 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25155 b0ffdc3ebf9430384b0161a65e1216f5 447 SUPERFAMILY SSF55931 108 444 9.22E-118 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UA74_25155 b0ffdc3ebf9430384b0161a65e1216f5 447 Pfam PF00120 Glutamine synthetase, catalytic domain 107 441 1.5E-126 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25155 b0ffdc3ebf9430384b0161a65e1216f5 447 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 Gene3D G3DSA:2.30.42.10 499 589 1.5E-26 T 12-10-2018 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 SMART SM00228 501 573 1.0E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 SUPERFAMILY SSF50494 285 496 1.81E-55 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 Gene3D G3DSA:2.40.10.10 279 374 4.8E-30 T 12-10-2018 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 Gene3D G3DSA:2.40.10.10 375 498 9.6E-44 T 12-10-2018 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 Pfam PF13180 PDZ domain 501 583 5.0E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 Pfam PF13365 Trypsin-like peptidase domain 311 456 8.4E-32 T 12-10-2018 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 PRINTS PR00834 HtrA/DegQ protease family signature 531 543 8.4E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 PRINTS PR00834 HtrA/DegQ protease family signature 427 444 8.4E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 PRINTS PR00834 HtrA/DegQ protease family signature 320 332 8.4E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 PRINTS PR00834 HtrA/DegQ protease family signature 449 466 8.4E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 PRINTS PR00834 HtrA/DegQ protease family signature 385 409 8.4E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 PRINTS PR00834 HtrA/DegQ protease family signature 344 364 8.4E-45 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_03235 4b6a2a9757f7da0b062b2da34fdaa447 590 SUPERFAMILY SSF50156 472 573 3.55E-16 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 UA74_20760 7ce9b9b797ee3770a0980d548c809802 243 Gene3D G3DSA:3.10.350.10 181 226 4.2E-6 T 12-10-2018 IPR036779 LysM domain superfamily UA74_20760 7ce9b9b797ee3770a0980d548c809802 243 Pfam PF01476 LysM domain 183 229 1.8E-4 T 12-10-2018 IPR018392 LysM domain UA74_12550 5b92c87ebf37add2688f24b5666e290c 139 Gene3D G3DSA:3.30.300.130 31 134 4.2E-31 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UA74_12550 5b92c87ebf37add2688f24b5666e290c 139 SUPERFAMILY SSF117916 36 133 5.56E-27 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UA74_12550 5b92c87ebf37add2688f24b5666e290c 139 Pfam PF01883 Iron-sulfur cluster assembly protein 37 102 4.6E-20 T 12-10-2018 IPR002744 MIP18 family-like UA74_12815 6bc77cbbb462e45124eb2931068a98c8 103 SUPERFAMILY SSF54909 1 98 4.95E-27 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_12815 6bc77cbbb462e45124eb2931068a98c8 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 4.0E-12 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_12815 6bc77cbbb462e45124eb2931068a98c8 103 Gene3D G3DSA:3.30.70.100 1 96 4.9E-37 T 12-10-2018 UA74_01855 b91da1f1585692e15258ce86146607da 959 SUPERFAMILY SSF52540 293 562 3.07E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01855 b91da1f1585692e15258ce86146607da 959 SMART SM01043 113 254 6.5E-39 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_01855 b91da1f1585692e15258ce86146607da 959 SMART SM00862 27 106 3.1E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_01855 b91da1f1585692e15258ce86146607da 959 SUPERFAMILY SSF48452 762 936 1.14E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_01855 b91da1f1585692e15258ce86146607da 959 SUPERFAMILY SSF46894 14 106 5.95E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_01855 b91da1f1585692e15258ce86146607da 959 PRINTS PR00364 Disease resistance protein signature 325 340 5.3E-7 T 12-10-2018 UA74_01855 b91da1f1585692e15258ce86146607da 959 PRINTS PR00364 Disease resistance protein signature 408 422 5.3E-7 T 12-10-2018 UA74_01855 b91da1f1585692e15258ce86146607da 959 PRINTS PR00364 Disease resistance protein signature 494 508 5.3E-7 T 12-10-2018 UA74_01855 b91da1f1585692e15258ce86146607da 959 Gene3D G3DSA:1.10.10.10 8 108 8.6E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_01855 b91da1f1585692e15258ce86146607da 959 Gene3D G3DSA:3.40.50.300 284 449 5.2E-24 T 12-10-2018 UA74_01855 b91da1f1585692e15258ce86146607da 959 Pfam PF03704 Bacterial transcriptional activator domain 114 254 3.5E-37 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_01855 b91da1f1585692e15258ce86146607da 959 Pfam PF00486 Transcriptional regulatory protein, C terminal 34 105 8.3E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_01855 b91da1f1585692e15258ce86146607da 959 Gene3D G3DSA:1.25.40.10 111 275 1.1E-40 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_01855 b91da1f1585692e15258ce86146607da 959 Gene3D G3DSA:1.25.40.10 717 947 3.1E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_01855 b91da1f1585692e15258ce86146607da 959 Pfam PF13424 Tetratricopeptide repeat 827 894 5.3E-8 T 12-10-2018 UA74_01855 b91da1f1585692e15258ce86146607da 959 Pfam PF00931 NB-ARC domain 323 509 6.8E-7 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_01855 b91da1f1585692e15258ce86146607da 959 SUPERFAMILY SSF48452 110 274 9.1E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_24915 f0d51f0985cc6f8e60e558e28db76012 269 PIRSF PIRSF000007 1 269 1.4E-117 T 12-10-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 UA74_24915 f0d51f0985cc6f8e60e558e28db76012 269 Gene3D G3DSA:1.10.760.10 149 230 1.8E-13 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_24915 f0d51f0985cc6f8e60e558e28db76012 269 SUPERFAMILY SSF46626 135 225 3.01E-27 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_24915 f0d51f0985cc6f8e60e558e28db76012 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 150 223 1.2E-11 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_24915 f0d51f0985cc6f8e60e558e28db76012 269 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 54 129 6.9E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_24915 f0d51f0985cc6f8e60e558e28db76012 269 Gene3D G3DSA:1.10.760.10 9 134 6.8E-10 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_24915 f0d51f0985cc6f8e60e558e28db76012 269 SUPERFAMILY SSF46626 23 135 1.86E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UA74_04925 0aa82937383322abc407459327ad5bb7 229 SMART SM00382 28 215 3.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_04925 0aa82937383322abc407459327ad5bb7 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_04925 0aa82937383322abc407459327ad5bb7 229 Gene3D G3DSA:3.40.50.300 1 224 1.9E-68 T 12-10-2018 UA74_04925 0aa82937383322abc407459327ad5bb7 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 1.3E-85 T 12-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 UA74_04925 0aa82937383322abc407459327ad5bb7 229 Pfam PF00005 ABC transporter 19 166 2.9E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_04925 0aa82937383322abc407459327ad5bb7 229 SUPERFAMILY SSF52540 1 220 1.87E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12410 fd60e1c07cecbe758f496beefcaea4b6 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 267 288 8.3E-10 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12410 fd60e1c07cecbe758f496beefcaea4b6 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 193 211 8.3E-10 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12410 fd60e1c07cecbe758f496beefcaea4b6 543 PRINTS PR00662 Glucose-6-phosphate isomerase signature 89 108 8.3E-10 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12410 fd60e1c07cecbe758f496beefcaea4b6 543 Gene3D G3DSA:3.40.50.10490 52 218 8.2E-36 T 12-10-2018 UA74_12410 fd60e1c07cecbe758f496beefcaea4b6 543 Gene3D G3DSA:3.40.50.10490 326 381 1.6E-10 T 12-10-2018 UA74_12410 fd60e1c07cecbe758f496beefcaea4b6 543 Gene3D G3DSA:3.40.50.10490 220 303 1.6E-8 T 12-10-2018 UA74_12410 fd60e1c07cecbe758f496beefcaea4b6 543 Pfam PF00342 Phosphoglucose isomerase 85 289 1.0E-6 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12410 fd60e1c07cecbe758f496beefcaea4b6 543 SUPERFAMILY SSF53697 26 380 2.22E-71 T 12-10-2018 UA74_10145 802b063ebe04d2977c7ca4820b4f654d 503 Pfam PF01593 Flavin containing amine oxidoreductase 15 485 5.9E-45 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_10145 802b063ebe04d2977c7ca4820b4f654d 503 SUPERFAMILY SSF51905 1 485 1.26E-63 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10145 802b063ebe04d2977c7ca4820b4f654d 503 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 8 487 1.7E-152 T 12-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 UA74_10145 802b063ebe04d2977c7ca4820b4f654d 503 Gene3D G3DSA:3.50.50.60 199 323 7.1E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10145 802b063ebe04d2977c7ca4820b4f654d 503 Gene3D G3DSA:3.50.50.60 5 114 2.9E-21 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_03330 ed42ac4e7edee6c2a103ce10e182de36 290 Pfam PF00248 Aldo/keto reductase family 14 285 1.1E-53 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_03330 ed42ac4e7edee6c2a103ce10e182de36 290 SUPERFAMILY SSF51430 3 285 7.2E-69 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_03330 ed42ac4e7edee6c2a103ce10e182de36 290 Gene3D G3DSA:3.20.20.100 1 289 6.1E-71 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_26860 3f010780ba97c2c2744a56799cc78505 287 Pfam PF02237 Biotin protein ligase C terminal domain 236 283 1.1E-10 T 12-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_26860 3f010780ba97c2c2744a56799cc78505 287 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 143 1.2E-9 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UA74_26860 3f010780ba97c2c2744a56799cc78505 287 SUPERFAMILY SSF50037 239 283 1.92E-7 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal UA74_26860 3f010780ba97c2c2744a56799cc78505 287 Gene3D G3DSA:2.30.30.100 237 285 2.1E-18 T 12-10-2018 UA74_26860 3f010780ba97c2c2744a56799cc78505 287 SUPERFAMILY SSF55681 27 223 3.64E-42 T 12-10-2018 UA74_26860 3f010780ba97c2c2744a56799cc78505 287 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 31 283 1.1E-37 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_26860 3f010780ba97c2c2744a56799cc78505 287 Gene3D G3DSA:3.30.930.10 1 235 1.2E-62 T 12-10-2018 UA74_17855 61e966a7a0419b2b2f486e06a8ed13f7 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 265 9.7E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_17855 61e966a7a0419b2b2f486e06a8ed13f7 280 Gene3D G3DSA:1.10.3720.10 7 271 2.9E-56 T 12-10-2018 IPR035906 MetI-like superfamily UA74_17855 61e966a7a0419b2b2f486e06a8ed13f7 280 SUPERFAMILY SSF161098 19 280 1.26E-63 T 12-10-2018 IPR035906 MetI-like superfamily UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 Gene3D G3DSA:2.40.33.10 39 133 1.0E-119 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 Gene3D G3DSA:3.40.1380.20 310 436 4.3E-32 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 Pfam PF02887 Pyruvate kinase, alpha/beta domain 322 433 8.2E-26 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 1 434 1.0E-154 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 PRINTS PR01050 Pyruvate kinase family signature 235 259 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 PRINTS PR01050 Pyruvate kinase family signature 27 43 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 PRINTS PR01050 Pyruvate kinase family signature 210 234 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 PRINTS PR01050 Pyruvate kinase family signature 260 278 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 PRINTS PR01050 Pyruvate kinase family signature 152 166 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 PRINTS PR01050 Pyruvate kinase family signature 279 295 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 PRINTS PR01050 Pyruvate kinase family signature 183 209 4.8E-66 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 Gene3D G3DSA:3.20.20.60 1 298 1.0E-119 T 12-10-2018 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 SUPERFAMILY SSF51621 1 305 2.97E-81 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 SUPERFAMILY SSF52935 289 435 2.35E-36 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 ProSitePatterns PS00110 Pyruvate kinase active site signature. 181 193 - T 12-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 SUPERFAMILY SSF50800 38 132 7.15E-26 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily UA74_21315 e56fb344ed1f4589543bc4c7ecf337b8 441 Pfam PF00224 Pyruvate kinase, barrel domain 1 304 1.6E-105 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UA74_23255 dbde98409c19ae8bafb95d0dcdf36f6b 258 Pfam PF12697 Alpha/beta hydrolase family 4 247 1.1E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_23255 dbde98409c19ae8bafb95d0dcdf36f6b 258 PRINTS PR00412 Epoxide hydrolase signature 70 83 2.1E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_23255 dbde98409c19ae8bafb95d0dcdf36f6b 258 PRINTS PR00412 Epoxide hydrolase signature 7 25 2.1E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_23255 dbde98409c19ae8bafb95d0dcdf36f6b 258 PRINTS PR00412 Epoxide hydrolase signature 27 42 2.1E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_23255 dbde98409c19ae8bafb95d0dcdf36f6b 258 PRINTS PR00412 Epoxide hydrolase signature 231 253 2.1E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_23255 dbde98409c19ae8bafb95d0dcdf36f6b 258 Gene3D G3DSA:3.40.50.1820 1 254 2.2E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23255 dbde98409c19ae8bafb95d0dcdf36f6b 258 SUPERFAMILY SSF53474 3 256 2.13E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_11910 dc53c8b96dfd5d8d558e03eabfe66d4b 834 SMART SM00490 277 363 1.7E-12 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_11910 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Pfam PF00270 DEAD/DEAH box helicase 33 180 6.9E-10 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_11910 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Gene3D G3DSA:3.40.50.300 13 197 8.3E-38 T 12-10-2018 UA74_11910 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Pfam PF12029 Domain of unknown function (DUF3516) 374 829 1.9E-214 T 12-10-2018 IPR021904 Protein of unknown function DUF3516 UA74_11910 dc53c8b96dfd5d8d558e03eabfe66d4b 834 SMART SM00487 27 211 1.2E-15 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_11910 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Pfam PF00271 Helicase conserved C-terminal domain 284 363 6.6E-6 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_11910 dc53c8b96dfd5d8d558e03eabfe66d4b 834 Gene3D G3DSA:3.40.50.300 198 384 7.6E-43 T 12-10-2018 UA74_11910 dc53c8b96dfd5d8d558e03eabfe66d4b 834 SUPERFAMILY SSF52540 46 375 7.53E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:1.10.8.280 186 293 1.1E-107 T 12-10-2018 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:1.20.1580.10 586 724 1.7E-124 T 12-10-2018 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 SMART SM00382 527 802 0.012 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 SMART SM00382 41 454 2.0 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 ProSitePatterns PS00211 ABC transporters family signature. 724 738 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:1.20.1580.10 149 382 1.1E-107 T 12-10-2018 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 ProSitePatterns PS00211 ABC transporters family signature. 377 391 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 149 819 1.4E-241 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:1.20.1580.10 109 148 1.3E-56 T 12-10-2018 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 SUPERFAMILY SSF52540 514 804 3.59E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 SUPERFAMILY SSF52540 22 453 1.33E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:3.40.50.300 511 827 1.7E-124 T 12-10-2018 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:3.40.50.300 383 483 1.1E-107 T 12-10-2018 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 Gene3D G3DSA:3.40.50.300 24 107 1.3E-56 T 12-10-2018 UA74_18790 ab11fb78f555dd392efa10cbe699ff57 835 Pfam PF00005 ABC transporter 518 754 1.5E-8 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_23720 a8f5c2d81b1e02bb1e86e98a4216079b 377 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 22 359 2.4E-121 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UA74_23720 a8f5c2d81b1e02bb1e86e98a4216079b 377 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 35 44 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UA74_23720 a8f5c2d81b1e02bb1e86e98a4216079b 377 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 152 168 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UA74_23720 a8f5c2d81b1e02bb1e86e98a4216079b 377 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 19 361 47.32 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UA74_23720 a8f5c2d81b1e02bb1e86e98a4216079b 377 SUPERFAMILY SSF51726 22 361 3.66E-103 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_23720 a8f5c2d81b1e02bb1e86e98a4216079b 377 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 19 359 2.4E-126 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UA74_23720 a8f5c2d81b1e02bb1e86e98a4216079b 377 Gene3D G3DSA:3.20.20.210 10 366 2.2E-142 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_01040 d2dcb983344772df1f9cf655181b5b0c 564 PIRSF PIRSF002741 5 563 2.2E-92 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_01040 d2dcb983344772df1f9cf655181b5b0c 564 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 479 1.6E-74 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_01040 d2dcb983344772df1f9cf655181b5b0c 564 Gene3D G3DSA:3.10.105.10 318 538 9.8E-127 T 12-10-2018 UA74_01040 d2dcb983344772df1f9cf655181b5b0c 564 Gene3D G3DSA:3.40.190.10 235 551 9.8E-127 T 12-10-2018 UA74_01040 d2dcb983344772df1f9cf655181b5b0c 564 SUPERFAMILY SSF53850 43 562 1.38E-106 T 12-10-2018 UA74_01040 d2dcb983344772df1f9cf655181b5b0c 564 Gene3D G3DSA:3.90.76.10 61 234 9.8E-127 T 12-10-2018 UA74_24500 077825d934380fea2747784317815e5f 127 PRINTS PR00332 Histidine triad family signature 9 25 4.5E-16 T 12-10-2018 IPR001310 Histidine triad (HIT) protein UA74_24500 077825d934380fea2747784317815e5f 127 PRINTS PR00332 Histidine triad family signature 98 108 4.5E-16 T 12-10-2018 IPR001310 Histidine triad (HIT) protein UA74_24500 077825d934380fea2747784317815e5f 127 PRINTS PR00332 Histidine triad family signature 30 48 4.5E-16 T 12-10-2018 IPR001310 Histidine triad (HIT) protein UA74_24500 077825d934380fea2747784317815e5f 127 Gene3D G3DSA:3.30.428.10 1 114 2.9E-34 T 12-10-2018 IPR036265 HIT-like superfamily UA74_24500 077825d934380fea2747784317815e5f 127 Pfam PF01230 HIT domain 16 111 8.6E-23 T 12-10-2018 IPR001310 Histidine triad (HIT) protein UA74_24500 077825d934380fea2747784317815e5f 127 SUPERFAMILY SSF54197 6 115 2.63E-33 T 12-10-2018 IPR036265 HIT-like superfamily UA74_09770 c6e0bac01b935462f80619d7366bd24d 265 SMART SM00530 15 88 8.1E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_09770 c6e0bac01b935462f80619d7366bd24d 265 Pfam PF13560 Helix-turn-helix domain 12 91 5.7E-16 T 12-10-2018 UA74_09770 c6e0bac01b935462f80619d7366bd24d 265 Gene3D G3DSA:1.10.260.40 8 99 3.5E-11 T 12-10-2018 UA74_09770 c6e0bac01b935462f80619d7366bd24d 265 SUPERFAMILY SSF47413 36 86 2.67E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_09770 c6e0bac01b935462f80619d7366bd24d 265 Gene3D G3DSA:3.30.450.180 111 265 1.1E-8 T 12-10-2018 UA74_25975 f45c7dbce9db2e796d2aa661ed846a58 722 Gene3D G3DSA:3.30.200.20 5 93 4.6E-17 T 12-10-2018 UA74_25975 f45c7dbce9db2e796d2aa661ed846a58 722 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_25975 f45c7dbce9db2e796d2aa661ed846a58 722 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 133 145 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 UA74_25975 f45c7dbce9db2e796d2aa661ed846a58 722 SUPERFAMILY SSF56112 11 267 1.17E-58 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_25975 f45c7dbce9db2e796d2aa661ed846a58 722 Gene3D G3DSA:1.10.510.10 95 270 6.1E-40 T 12-10-2018 UA74_25975 f45c7dbce9db2e796d2aa661ed846a58 722 Pfam PF00069 Protein kinase domain 16 262 2.4E-32 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_04415 bfdd8b8e724aabf111e17fad7cc01d49 340 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 38 322 2.2E-87 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 UA74_04415 bfdd8b8e724aabf111e17fad7cc01d49 340 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 7 327 3.7E-94 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 UA74_04415 bfdd8b8e724aabf111e17fad7cc01d49 340 SUPERFAMILY SSF53659 5 328 4.07E-97 T 12-10-2018 UA74_04415 bfdd8b8e724aabf111e17fad7cc01d49 340 Gene3D G3DSA:3.40.718.10 1 330 6.2E-112 T 12-10-2018 UA74_23080 4e46bcdaee4286193d893390b8cedff0 257 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 5 151 1.9E-41 T 12-10-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 UA74_23080 4e46bcdaee4286193d893390b8cedff0 257 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 5 237 3.7E-43 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_23080 4e46bcdaee4286193d893390b8cedff0 257 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 5 45 7.5E-8 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_23080 4e46bcdaee4286193d893390b8cedff0 257 Gene3D G3DSA:3.30.70.2660 3 250 2.6E-49 T 12-10-2018 UA74_13600 83912254e876cd0e4d8785512b255cfb 395 SUPERFAMILY SSF47203 234 390 4.67E-17 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_13600 83912254e876cd0e4d8785512b255cfb 395 Gene3D G3DSA:1.20.140.10 221 395 6.9E-51 T 12-10-2018 UA74_13600 83912254e876cd0e4d8785512b255cfb 395 Gene3D G3DSA:1.10.540.10 9 116 4.0E-25 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_13600 83912254e876cd0e4d8785512b255cfb 395 Gene3D G3DSA:2.40.110.10 120 214 9.3E-20 T 12-10-2018 UA74_13600 83912254e876cd0e4d8785512b255cfb 395 PIRSF PIRSF016578 1 391 2.5E-34 T 12-10-2018 UA74_13600 83912254e876cd0e4d8785512b255cfb 395 SUPERFAMILY SSF56645 14 213 6.94E-37 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_13600 83912254e876cd0e4d8785512b255cfb 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 87 3.1E-5 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UA74_13600 83912254e876cd0e4d8785512b255cfb 395 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 370 5.1E-15 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain UA74_02480 a60897d283c5b06c33fa7bdb285ee85a 296 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 18 291 5.6E-85 T 12-10-2018 UA74_02480 a60897d283c5b06c33fa7bdb285ee85a 296 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 9 293 20.651 T 12-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 UA74_02480 a60897d283c5b06c33fa7bdb285ee85a 296 PIRSF PIRSF005355 1 296 1.9E-83 T 12-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 UA74_02480 a60897d283c5b06c33fa7bdb285ee85a 296 Pfam PF01040 UbiA prenyltransferase family 26 256 1.9E-33 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 SUPERFAMILY SSF46894 855 917 1.56E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 Gene3D G3DSA:1.10.10.10 860 921 1.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 Pfam PF13191 AAA ATPase domain 11 174 5.3E-15 T 12-10-2018 UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 SMART SM00421 863 920 6.6E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 ProSitePatterns PS00622 LuxR-type HTH domain signature. 880 907 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 866 880 5.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 896 908 5.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 880 896 5.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 Pfam PF00196 Bacterial regulatory proteins, luxR family 864 916 3.9E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17300 5e49523b73367c82e14c7b9c78e64476 922 Gene3D G3DSA:1.25.40.10 477 844 3.3E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19055 cf0afeb165139dbc67eac12ecf3adb6f 130 Gene3D G3DSA:1.10.1900.10 13 125 3.3E-36 T 12-10-2018 UA74_19055 cf0afeb165139dbc67eac12ecf3adb6f 130 Pfam PF06304 Protein of unknown function (DUF1048) 22 122 8.8E-27 T 12-10-2018 IPR008316 Uncharacterised conserved protein UCP029876 UA74_19055 cf0afeb165139dbc67eac12ecf3adb6f 130 SUPERFAMILY SSF158560 15 122 9.16E-27 T 12-10-2018 UA74_12275 407bc7f38af3e48ecea15be8227c327c 309 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 304 7.1E-63 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 UA74_12275 407bc7f38af3e48ecea15be8227c327c 309 SUPERFAMILY SSF53328 1 206 2.35E-53 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_12275 407bc7f38af3e48ecea15be8227c327c 309 SUPERFAMILY SSF50486 205 308 7.85E-23 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 UA74_12275 407bc7f38af3e48ecea15be8227c327c 309 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 303 30.472 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 UA74_12275 407bc7f38af3e48ecea15be8227c327c 309 Pfam PF00551 Formyl transferase 7 178 1.3E-29 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_12275 407bc7f38af3e48ecea15be8227c327c 309 Pfam PF02911 Formyl transferase, C-terminal domain 204 300 1.4E-17 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_12275 407bc7f38af3e48ecea15be8227c327c 309 Gene3D G3DSA:3.40.50.12230 1 308 9.1E-84 T 12-10-2018 UA74_12830 ebb5b00a640e0d724b280ff876f0751b 376 SUPERFAMILY SSF54631 263 373 1.39E-5 T 12-10-2018 UA74_12830 ebb5b00a640e0d724b280ff876f0751b 376 Pfam PF02163 Peptidase family M50 151 198 1.1E-6 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 UA74_12830 ebb5b00a640e0d724b280ff876f0751b 376 PIRSF PIRSF006404 14 376 4.7E-62 T 12-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS UA74_11440 d6b8e7d655854f89fd06f04932a03c6e 415 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 15 415 30.121 T 12-10-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_11440 d6b8e7d655854f89fd06f04932a03c6e 415 Gene3D G3DSA:3.30.590.20 5 409 8.0E-86 T 12-10-2018 UA74_11440 d6b8e7d655854f89fd06f04932a03c6e 415 SUPERFAMILY SSF55931 31 365 2.26E-30 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UA74_11440 d6b8e7d655854f89fd06f04932a03c6e 415 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 41 338 1.5E-44 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_11440 d6b8e7d655854f89fd06f04932a03c6e 415 PIRSF PIRSF017901 5 407 2.6E-82 T 12-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_08585 69c4062172c690ea7ecbeb75e49f4f37 242 Pfam PF00005 ABC transporter 17 165 4.6E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_08585 69c4062172c690ea7ecbeb75e49f4f37 242 SUPERFAMILY SSF52540 1 235 4.69E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08585 69c4062172c690ea7ecbeb75e49f4f37 242 Gene3D G3DSA:3.40.50.300 1 242 1.4E-78 T 12-10-2018 UA74_08585 69c4062172c690ea7ecbeb75e49f4f37 242 PIRSF PIRSF039085 1 241 1.8E-111 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UA74_08585 69c4062172c690ea7ecbeb75e49f4f37 242 SMART SM00382 26 213 5.6E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_08585 69c4062172c690ea7ecbeb75e49f4f37 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22710 0360f97507fd321567f577e9beee4e66 429 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 41 142 2.2E-4 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_22710 0360f97507fd321567f577e9beee4e66 429 Gene3D G3DSA:3.20.20.120 142 385 2.2E-188 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_22710 0360f97507fd321567f577e9beee4e66 429 Pfam PF13378 Enolase C-terminal domain-like 179 392 3.9E-52 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_22710 0360f97507fd321567f577e9beee4e66 429 Gene3D G3DSA:3.30.390.10 12 422 2.2E-188 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_22710 0360f97507fd321567f577e9beee4e66 429 SUPERFAMILY SSF54826 10 142 1.33E-24 T 12-10-2018 UA74_22710 0360f97507fd321567f577e9beee4e66 429 SUPERFAMILY SSF51604 142 401 1.57E-75 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_22710 0360f97507fd321567f577e9beee4e66 429 SMART SM00922 176 270 5.4E-26 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_09925 2126820cdf08e68535a5aa10126b5953 199 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 199 40.597 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UA74_09925 2126820cdf08e68535a5aa10126b5953 199 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 179 4.7E-59 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UA74_09925 2126820cdf08e68535a5aa10126b5953 199 Gene3D G3DSA:3.30.230.40 91 199 1.2E-34 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 UA74_09925 2126820cdf08e68535a5aa10126b5953 199 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 161 173 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UA74_09925 2126820cdf08e68535a5aa10126b5953 199 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UA74_09925 2126820cdf08e68535a5aa10126b5953 199 SUPERFAMILY SSF54211 88 184 3.79E-28 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_09925 2126820cdf08e68535a5aa10126b5953 199 SUPERFAMILY SSF54211 3 86 4.68E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_09925 2126820cdf08e68535a5aa10126b5953 199 Gene3D G3DSA:3.30.230.40 1 90 1.1E-36 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 UA74_21185 598218de20d0ccfa24851059690a20eb 281 SUPERFAMILY SSF48498 98 211 5.48E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_21185 598218de20d0ccfa24851059690a20eb 281 Gene3D G3DSA:1.10.357.10 67 213 2.6E-28 T 12-10-2018 UA74_21185 598218de20d0ccfa24851059690a20eb 281 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 76 2.4E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_21185 598218de20d0ccfa24851059690a20eb 281 SUPERFAMILY SSF46689 16 101 1.2E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_21185 598218de20d0ccfa24851059690a20eb 281 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_21185 598218de20d0ccfa24851059690a20eb 281 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_21185 598218de20d0ccfa24851059690a20eb 281 Gene3D G3DSA:1.10.10.60 14 66 4.1E-21 T 12-10-2018 UA74_03205 b8ffe30692ed04bafd0378ba40747c34 508 SUPERFAMILY SSF55073 332 489 1.57E-40 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_03205 b8ffe30692ed04bafd0378ba40747c34 508 SUPERFAMILY SSF48452 161 259 4.34E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03205 b8ffe30692ed04bafd0378ba40747c34 508 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 325 490 1.3E-40 T 12-10-2018 IPR000160 GGDEF domain UA74_03205 b8ffe30692ed04bafd0378ba40747c34 508 SMART SM00267 316 490 7.1E-44 T 12-10-2018 IPR000160 GGDEF domain UA74_03205 b8ffe30692ed04bafd0378ba40747c34 508 Pfam PF00990 Diguanylate cyclase, GGDEF domain 327 486 1.4E-37 T 12-10-2018 IPR000160 GGDEF domain UA74_03205 b8ffe30692ed04bafd0378ba40747c34 508 Gene3D G3DSA:3.30.70.270 325 494 3.8E-48 T 12-10-2018 UA74_03205 b8ffe30692ed04bafd0378ba40747c34 508 Gene3D G3DSA:1.25.40.10 15 324 2.5E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_29125 b4109ced0a1b77c4c684f924e5154356 281 Pfam PF12697 Alpha/beta hydrolase family 48 230 2.3E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_29125 b4109ced0a1b77c4c684f924e5154356 281 SUPERFAMILY SSF53474 12 263 2.81E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_14885 236a1d6be85fe672d429ce87fb06e1e3 220 SUPERFAMILY SSF56784 1 202 9.03E-26 T 12-10-2018 IPR036412 HAD-like superfamily UA74_14885 236a1d6be85fe672d429ce87fb06e1e3 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 91 190 8.6E-9 T 12-10-2018 UA74_14885 236a1d6be85fe672d429ce87fb06e1e3 220 Gene3D G3DSA:3.40.50.1000 1 212 2.9E-23 T 12-10-2018 IPR023214 HAD superfamily UA74_27440 e9c105524eb24df7262909dc2ce83795 203 SMART SM00860 28 164 6.8E-5 T 12-10-2018 IPR018958 Knr4/Smi1-like domain UA74_27440 e9c105524eb24df7262909dc2ce83795 203 Gene3D G3DSA:3.40.1580.10 18 172 2.7E-5 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily UA74_27440 e9c105524eb24df7262909dc2ce83795 203 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 28 145 2.1E-9 T 12-10-2018 IPR018958 Knr4/Smi1-like domain UA74_27440 e9c105524eb24df7262909dc2ce83795 203 SUPERFAMILY SSF160631 22 165 1.44E-10 T 12-10-2018 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 Gene3D G3DSA:3.10.150.10 140 264 2.9E-33 T 12-10-2018 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 Gene3D G3DSA:3.10.150.10 265 389 2.4E-43 T 12-10-2018 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 SMART SM00480 17 383 7.5E-121 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 Pfam PF02767 DNA polymerase III beta subunit, central domain 146 260 1.1E-31 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 387 2.4E-95 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 SUPERFAMILY SSF55979 262 387 1.3E-30 T 12-10-2018 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 39 5.0E-7 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 54 134 1.0E-21 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 PIRSF PIRSF000804 1 388 7.6E-97 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 SUPERFAMILY SSF55979 1 134 1.75E-19 T 12-10-2018 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 SUPERFAMILY SSF55979 146 261 2.77E-19 T 12-10-2018 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 Gene3D G3DSA:3.10.150.10 1 137 3.2E-41 T 12-10-2018 UA74_00010 1e26a031a5d98a6d7446cfe7945b6486 389 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 262 372 2.4E-32 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 Pfam PF04542 Sigma-70 region 2 55 120 1.2E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 Gene3D G3DSA:1.10.1740.10 30 135 8.4E-31 T 12-10-2018 UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 Pfam PF12680 SnoaL-like domain 250 356 1.2E-7 T 12-10-2018 IPR037401 SnoaL-like domain UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 48 369 3.2E-105 T 12-10-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 Gene3D G3DSA:3.10.450.50 232 360 3.6E-12 T 12-10-2018 UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 Gene3D G3DSA:1.10.10.10 150 229 6.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 SUPERFAMILY SSF88946 35 127 2.75E-29 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 77 108 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 51 228 2.2E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 Pfam PF08281 Sigma-70, region 4 173 224 5.5E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 SUPERFAMILY SSF54427 248 359 3.97E-12 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_18545 45d6879bce9bd4c72b93e1fb28a1c531 395 SUPERFAMILY SSF88659 170 228 3.74E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_15780 d54c7586e758371308c5056f26091a5f 379 PIRSF PIRSF016578 1 376 2.3E-59 T 12-10-2018 UA74_15780 d54c7586e758371308c5056f26091a5f 379 Gene3D G3DSA:1.20.140.10 209 373 3.3E-25 T 12-10-2018 UA74_15780 d54c7586e758371308c5056f26091a5f 379 SUPERFAMILY SSF56645 17 196 4.43E-18 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_15780 d54c7586e758371308c5056f26091a5f 379 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 229 358 3.1E-14 T 12-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain UA74_15780 d54c7586e758371308c5056f26091a5f 379 Gene3D G3DSA:2.40.110.10 113 204 5.3E-18 T 12-10-2018 UA74_15780 d54c7586e758371308c5056f26091a5f 379 SUPERFAMILY SSF47203 225 356 9.14E-8 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_15780 d54c7586e758371308c5056f26091a5f 379 Gene3D G3DSA:1.10.540.10 5 112 6.0E-14 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_20100 22afb0b73a3bee1d2dd504a85417fb33 278 Pfam PF17197 Domain of unknown function (DUF5134) 38 277 2.0E-27 T 12-10-2018 IPR033458 Protein of unknown function DUF5134 UA74_20100 22afb0b73a3bee1d2dd504a85417fb33 278 ProDom PD338207 MEMBRANE INTEGRAL TRANSMEMBRANE PLASMID PROBABLE MB0995 RV0970/MT0998 7 117 3.0E-11 T 12-10-2018 UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 378 6.1E-139 T 12-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 SUPERFAMILY SSF53448 7 359 1.01E-69 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 404 47.426 T 12-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 Gene3D G3DSA:3.90.550.10 2 291 6.5E-82 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 196 206 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 Gene3D G3DSA:2.160.10.10 292 405 1.5E-33 T 12-10-2018 UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 SUPERFAMILY SSF51161 298 398 2.77E-18 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily UA74_04570 c4d9ff34fa26c975b52f7b23d2ed92cb 406 Pfam PF00483 Nucleotidyl transferase 9 276 2.0E-69 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_17890 48a806255ae1ad955147264b904a7b10 379 Pfam PF00296 Luciferase-like monooxygenase 1 293 6.4E-55 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_17890 48a806255ae1ad955147264b904a7b10 379 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 354 4.7E-214 T 12-10-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative UA74_17890 48a806255ae1ad955147264b904a7b10 379 Gene3D G3DSA:3.20.20.30 1 341 2.4E-66 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_17890 48a806255ae1ad955147264b904a7b10 379 SUPERFAMILY SSF51679 1 333 3.4E-70 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_19930 d93ca96493a75cd05973f569c56b6400 252 SUPERFAMILY SSF53474 4 237 4.47E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19930 d93ca96493a75cd05973f569c56b6400 252 Pfam PF12697 Alpha/beta hydrolase family 23 227 7.5E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19930 d93ca96493a75cd05973f569c56b6400 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 2.4E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19930 d93ca96493a75cd05973f569c56b6400 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.4E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19930 d93ca96493a75cd05973f569c56b6400 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.4E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19930 d93ca96493a75cd05973f569c56b6400 252 Gene3D G3DSA:3.40.50.1820 2 239 9.1E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19920 fe5f399ebd28a640958e60b46bf49895 657 Gene3D G3DSA:3.30.565.10 476 586 1.6E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_19920 fe5f399ebd28a640958e60b46bf49895 657 Gene3D G3DSA:3.30.565.10 307 455 1.4E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_19920 fe5f399ebd28a640958e60b46bf49895 657 SUPERFAMILY SSF55874 545 585 3.46E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_19920 fe5f399ebd28a640958e60b46bf49895 657 SUPERFAMILY SSF55874 313 385 2.26E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_19920 fe5f399ebd28a640958e60b46bf49895 657 Pfam PF07730 Histidine kinase 205 267 1.6E-8 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_12985 b4ef09699c87d31a80646509d7f98c93 229 Gene3D G3DSA:3.40.50.300 10 229 1.9E-54 T 12-10-2018 UA74_12985 b4ef09699c87d31a80646509d7f98c93 229 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_12985 b4ef09699c87d31a80646509d7f98c93 229 Pfam PF00005 ABC transporter 32 178 2.7E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_12985 b4ef09699c87d31a80646509d7f98c93 229 SMART SM00382 41 225 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_12985 b4ef09699c87d31a80646509d7f98c93 229 SUPERFAMILY SSF52540 10 227 6.23E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_09780 2455a4bd1d685ea15f7d492f54086256 281 Pfam PF14062 Domain of unknown function (DUF4253) 173 281 6.9E-40 T 12-10-2018 IPR025349 Domain of unknown function DUF4253 UA74_02850 1c200a6a3b987f36937a886612a49ef2 186 Gene3D G3DSA:3.30.70.1730 1 168 6.1E-37 T 12-10-2018 UA74_02850 1c200a6a3b987f36937a886612a49ef2 186 SUPERFAMILY SSF160369 1 169 1.01E-48 T 12-10-2018 UA74_02850 1c200a6a3b987f36937a886612a49ef2 186 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 66 140 0.006 T 12-10-2018 UA74_02850 1c200a6a3b987f36937a886612a49ef2 186 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 25.058 T 12-10-2018 IPR022973 Ribosomal protein L10 UA74_02850 1c200a6a3b987f36937a886612a49ef2 186 Pfam PF00466 Ribosomal protein L10 1 98 7.6E-25 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 UA74_26500 4ccd97b86106ed5b8a44b49e0893eb3c 255 Gene3D G3DSA:3.30.1330.30 5 86 1.4E-7 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_26500 4ccd97b86106ed5b8a44b49e0893eb3c 255 Gene3D G3DSA:3.40.1280.10 101 255 8.6E-42 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_26500 4ccd97b86106ed5b8a44b49e0893eb3c 255 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 14 88 3.4E-13 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UA74_26500 4ccd97b86106ed5b8a44b49e0893eb3c 255 Pfam PF00588 SpoU rRNA Methylase family 106 243 2.7E-29 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_26500 4ccd97b86106ed5b8a44b49e0893eb3c 255 SUPERFAMILY SSF55315 8 84 2.0E-11 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_26500 4ccd97b86106ed5b8a44b49e0893eb3c 255 SMART SM00967 13 90 1.3E-9 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UA74_26500 4ccd97b86106ed5b8a44b49e0893eb3c 255 SUPERFAMILY SSF75217 90 252 1.05E-36 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_24765 89f3c67f4ddb40b169114a9ea371cd75 458 SUPERFAMILY SSF51569 11 457 6.96E-190 T 12-10-2018 UA74_24765 89f3c67f4ddb40b169114a9ea371cd75 458 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 27 457 4.1E-212 T 12-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 UA74_24765 89f3c67f4ddb40b169114a9ea371cd75 458 Pfam PF01474 Class-II DAHP synthetase family 31 453 1.2E-186 T 12-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 UA74_24765 89f3c67f4ddb40b169114a9ea371cd75 458 Gene3D G3DSA:3.20.20.70 208 458 6.3E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_16905 fd22e1e6ed0e9ee203f114bd3857da74 187 Gene3D G3DSA:1.10.10.10 18 113 6.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16905 fd22e1e6ed0e9ee203f114bd3857da74 187 Pfam PF12802 MarR family 47 106 5.6E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_16905 fd22e1e6ed0e9ee203f114bd3857da74 187 SUPERFAMILY SSF46785 30 121 3.75E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_09630 3870ece0908c1794d1c04a4677507d26 357 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 346 23.115 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_09630 3870ece0908c1794d1c04a4677507d26 357 ProSitePatterns PS01348 MraY family signature 2. 175 186 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_09630 3870ece0908c1794d1c04a4677507d26 357 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 342 6.8E-92 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_09630 3870ece0908c1794d1c04a4677507d26 357 Pfam PF00953 Glycosyl transferase family 4 82 272 7.3E-38 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 UA74_09630 3870ece0908c1794d1c04a4677507d26 357 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_09630 3870ece0908c1794d1c04a4677507d26 357 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 7.2E-6 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_11815 86f1c76afc67736c61a9b8eb969a5e3e 328 SUPERFAMILY SSF51735 5 160 3.29E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_11815 86f1c76afc67736c61a9b8eb969a5e3e 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 124 1.1E-23 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_11815 86f1c76afc67736c61a9b8eb969a5e3e 328 Gene3D G3DSA:3.40.50.720 3 128 2.3E-38 T 12-10-2018 UA74_11815 86f1c76afc67736c61a9b8eb969a5e3e 328 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 140 203 3.8E-4 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UA74_11815 86f1c76afc67736c61a9b8eb969a5e3e 328 Gene3D G3DSA:3.30.360.10 129 326 8.3E-52 T 12-10-2018 UA74_11815 86f1c76afc67736c61a9b8eb969a5e3e 328 SUPERFAMILY SSF55347 132 292 2.62E-37 T 12-10-2018 UA74_03590 0949f3912eeb2198f36aa82e91aa9127 204 SUPERFAMILY SSF46785 11 184 1.75E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_03590 0949f3912eeb2198f36aa82e91aa9127 204 Gene3D G3DSA:1.10.10.10 2 104 6.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_03590 0949f3912eeb2198f36aa82e91aa9127 204 Pfam PF03551 Transcriptional regulator PadR-like family 15 91 5.5E-11 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_14080 8d11225ad6aeb82d076f3c2338ff78b6 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 69 2.0E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14080 8d11225ad6aeb82d076f3c2338ff78b6 207 SUPERFAMILY SSF46689 19 71 4.58E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14080 8d11225ad6aeb82d076f3c2338ff78b6 207 Gene3D G3DSA:1.10.10.60 16 66 3.8E-21 T 12-10-2018 UA74_14080 8d11225ad6aeb82d076f3c2338ff78b6 207 Gene3D G3DSA:1.10.357.10 67 200 1.2E-15 T 12-10-2018 UA74_04420 747fdbe1a9fe8ab87413efc2740629df 351 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 265 297 1.3E-14 T 12-10-2018 IPR001451 Hexapeptide repeat UA74_04420 747fdbe1a9fe8ab87413efc2740629df 351 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 144 183 2.1E-20 T 12-10-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 UA74_04420 747fdbe1a9fe8ab87413efc2740629df 351 Gene3D G3DSA:2.160.10.10 184 351 1.9E-67 T 12-10-2018 UA74_04420 747fdbe1a9fe8ab87413efc2740629df 351 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 28 350 1.8E-151 T 12-10-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 UA74_04420 747fdbe1a9fe8ab87413efc2740629df 351 SUPERFAMILY SSF51161 114 330 3.05E-38 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily UA74_04420 747fdbe1a9fe8ab87413efc2740629df 351 Gene3D G3DSA:3.30.60.70 144 183 1.5E-23 T 12-10-2018 IPR038361 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain superfamily KEGG: 00300+2.3.1.117 UA74_04420 747fdbe1a9fe8ab87413efc2740629df 351 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 26 348 43.684 T 12-10-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 UA74_04420 747fdbe1a9fe8ab87413efc2740629df 351 Gene3D G3DSA:3.30.70.2010 21 143 5.8E-36 T 12-10-2018 UA74_16885 6cb53e265c0f5853684d7d3876964143 295 Gene3D G3DSA:3.30.450.180 105 292 5.8E-15 T 12-10-2018 UA74_16885 6cb53e265c0f5853684d7d3876964143 295 SMART SM00530 10 83 7.8E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_16885 6cb53e265c0f5853684d7d3876964143 295 Gene3D G3DSA:1.10.260.40 9 93 2.3E-8 T 12-10-2018 UA74_16885 6cb53e265c0f5853684d7d3876964143 295 SUPERFAMILY SSF47413 31 82 2.62E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_16885 6cb53e265c0f5853684d7d3876964143 295 Pfam PF13560 Helix-turn-helix domain 6 86 6.4E-16 T 12-10-2018 UA74_12285 d9bc613dda3d636ee6500df1a09a03c3 207 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 41 200 1.5E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_12285 d9bc613dda3d636ee6500df1a09a03c3 207 SUPERFAMILY SSF88659 139 202 5.01E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_12285 d9bc613dda3d636ee6500df1a09a03c3 207 Gene3D G3DSA:1.10.1740.10 23 112 1.0E-17 T 12-10-2018 UA74_12285 d9bc613dda3d636ee6500df1a09a03c3 207 Pfam PF08281 Sigma-70, region 4 146 198 1.1E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_12285 d9bc613dda3d636ee6500df1a09a03c3 207 Gene3D G3DSA:1.10.10.10 123 205 3.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12285 d9bc613dda3d636ee6500df1a09a03c3 207 SUPERFAMILY SSF88946 24 120 2.94E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_12285 d9bc613dda3d636ee6500df1a09a03c3 207 Pfam PF04542 Sigma-70 region 2 45 113 9.5E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_05095 0e5a78037933839566b76f33141d3471 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 43 177 4.5E-9 T 12-10-2018 UA74_05095 0e5a78037933839566b76f33141d3471 214 SUPERFAMILY SSF56784 1 207 2.18E-33 T 12-10-2018 IPR036412 HAD-like superfamily UA74_05095 0e5a78037933839566b76f33141d3471 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 170 1.9E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_05095 0e5a78037933839566b76f33141d3471 214 Gene3D G3DSA:3.40.50.1000 1 212 6.7E-28 T 12-10-2018 IPR023214 HAD superfamily UA74_03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 SUPERFAMILY SSF55021 242 327 5.84E-8 T 12-10-2018 UA74_03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 Gene3D G3DSA:3.40.50.300 1 262 3.5E-83 T 12-10-2018 UA74_03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 SUPERFAMILY SSF52540 1 238 9.54E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 Pfam PF09383 NIL domain 262 327 2.6E-9 T 12-10-2018 IPR018449 NIL domain UA74_03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 Pfam PF00005 ABC transporter 21 169 2.9E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 SMART SM00930 257 330 1.0E-10 T 12-10-2018 IPR018449 NIL domain UA74_03550 9cfde0c38d9ea68f78f37acbd6faaae7 339 SMART SM00382 30 217 3.8E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_24595 33512a20946a24155e2301b3a2315b9a 321 SUPERFAMILY SSF50129 13 156 7.23E-30 T 12-10-2018 IPR011032 GroES-like superfamily UA74_24595 33512a20946a24155e2301b3a2315b9a 321 Pfam PF00107 Zinc-binding dehydrogenase 167 282 2.1E-23 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_24595 33512a20946a24155e2301b3a2315b9a 321 Gene3D G3DSA:3.40.50.720 137 269 6.7E-77 T 12-10-2018 UA74_24595 33512a20946a24155e2301b3a2315b9a 321 SUPERFAMILY SSF51735 128 289 1.09E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_24595 33512a20946a24155e2301b3a2315b9a 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 123 6.1E-5 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_24595 33512a20946a24155e2301b3a2315b9a 321 SMART SM00829 13 319 7.6E-14 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_24595 33512a20946a24155e2301b3a2315b9a 321 Gene3D G3DSA:3.90.180.10 19 310 6.7E-77 T 12-10-2018 UA74_18080 aee28f71a8486707201c3c75e25023c4 546 Gene3D G3DSA:3.20.20.80 20 467 1.3E-150 T 12-10-2018 UA74_18080 aee28f71a8486707201c3c75e25023c4 546 Pfam PF11941 Domain of unknown function (DUF3459) 458 544 4.5E-10 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) UA74_18080 aee28f71a8486707201c3c75e25023c4 546 SUPERFAMILY SSF51445 18 472 1.67E-130 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_18080 aee28f71a8486707201c3c75e25023c4 546 SMART SM00642 28 410 3.1E-126 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_18080 aee28f71a8486707201c3c75e25023c4 546 Gene3D G3DSA:3.90.400.10 120 192 1.3E-150 T 12-10-2018 UA74_18080 aee28f71a8486707201c3c75e25023c4 546 Pfam PF00128 Alpha amylase, catalytic domain 43 381 1.1E-79 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_18570 431dc207a87bf7183c365db55790e006 139 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 11 136 8.3E-40 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 UA74_18570 431dc207a87bf7183c365db55790e006 139 Gene3D G3DSA:3.10.450.50 1 138 1.7E-42 T 12-10-2018 UA74_18570 431dc207a87bf7183c365db55790e006 139 Pfam PF14534 Domain of unknown function (DUF4440) 17 128 1.8E-12 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 UA74_18570 431dc207a87bf7183c365db55790e006 139 SUPERFAMILY SSF54427 10 138 2.1E-37 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_11830 6d9b28eac78b3839c0b3f5824d8b8437 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 253 2.3E-74 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_11830 6d9b28eac78b3839c0b3f5824d8b8437 255 Pfam PF00557 Metallopeptidase family M24 12 246 2.0E-40 T 12-10-2018 IPR000994 Peptidase M24 UA74_11830 6d9b28eac78b3839c0b3f5824d8b8437 255 SUPERFAMILY SSF55920 1 254 3.01E-70 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like UA74_11830 6d9b28eac78b3839c0b3f5824d8b8437 255 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 35.227 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_11830 6d9b28eac78b3839c0b3f5824d8b8437 255 Gene3D G3DSA:3.90.230.10 1 255 1.2E-82 T 12-10-2018 UA74_11830 6d9b28eac78b3839c0b3f5824d8b8437 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 9.1E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_11830 6d9b28eac78b3839c0b3f5824d8b8437 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 9.1E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_11830 6d9b28eac78b3839c0b3f5824d8b8437 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 9.1E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_11830 6d9b28eac78b3839c0b3f5824d8b8437 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 9.1E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_08950 a79dac5f314329fd78f3ecb597e2a757 250 Hamap MF_01220_B Uridylate kinase [pyrH]. 9 242 42.621 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 UA74_08950 a79dac5f314329fd78f3ecb597e2a757 250 PIRSF PIRSF005650 7 249 1.2E-86 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 UA74_08950 a79dac5f314329fd78f3ecb597e2a757 250 Gene3D G3DSA:3.40.1160.10 3 244 3.8E-76 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UA74_08950 a79dac5f314329fd78f3ecb597e2a757 250 SUPERFAMILY SSF53633 11 241 6.02E-69 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UA74_08950 a79dac5f314329fd78f3ecb597e2a757 250 Pfam PF00696 Amino acid kinase family 13 221 5.2E-28 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UA74_08950 a79dac5f314329fd78f3ecb597e2a757 250 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 12 242 6.6E-88 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 UA74_14055 0b0f70c32994966fd7f5054159163538 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.2E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_14055 0b0f70c32994966fd7f5054159163538 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.2E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_14055 0b0f70c32994966fd7f5054159163538 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.2E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_14055 0b0f70c32994966fd7f5054159163538 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 196 2.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_14055 0b0f70c32994966fd7f5054159163538 220 SUPERFAMILY SSF52172 1 167 1.49E-19 T 12-10-2018 IPR011006 CheY-like superfamily UA74_14055 0b0f70c32994966fd7f5054159163538 220 SMART SM00421 148 205 2.9E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_14055 0b0f70c32994966fd7f5054159163538 220 SMART SM00448 1 120 8.4E-9 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_14055 0b0f70c32994966fd7f5054159163538 220 Pfam PF00072 Response regulator receiver domain 3 108 1.3E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_14055 0b0f70c32994966fd7f5054159163538 220 Gene3D G3DSA:3.40.50.12740 1 214 3.0E-43 T 12-10-2018 UA74_18645 f11be2fe5341346704726d7658dc0027 778 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 592 769 1.4E-7 T 12-10-2018 UA74_18645 f11be2fe5341346704726d7658dc0027 778 SUPERFAMILY SSF50952 98 492 2.62E-11 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_18645 f11be2fe5341346704726d7658dc0027 778 Gene3D G3DSA:2.120.10.30 90 487 3.9E-46 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_18645 f11be2fe5341346704726d7658dc0027 778 Pfam PF07995 Glucose / Sorbosone dehydrogenase 93 460 9.4E-25 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase UA74_18645 f11be2fe5341346704726d7658dc0027 778 SUPERFAMILY SSF49899 504 774 1.13E-14 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UA74_18645 f11be2fe5341346704726d7658dc0027 778 Gene3D G3DSA:2.60.120.200 583 777 2.9E-13 T 12-10-2018 UA74_20595 43cce84929de96bd97f126806fda0cb7 361 Gene3D G3DSA:2.160.20.100 194 312 1.8E-8 T 12-10-2018 UA74_20595 43cce84929de96bd97f126806fda0cb7 361 Pfam PF00805 Pentapeptide repeats (8 copies) 197 236 1.2E-4 T 12-10-2018 IPR001646 Pentapeptide repeat UA74_20595 43cce84929de96bd97f126806fda0cb7 361 SUPERFAMILY SSF141571 195 246 2.35E-5 T 12-10-2018 UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 6 26 1.0E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 94 111 1.0E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 76 93 1.0E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 175 192 1.0E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 27 49 1.0E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 125 147 1.0E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 PRINTS PR00775 90kDa heat shock protein signature 198 216 1.0E-56 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 SUPERFAMILY SSF55874 5 221 5.63E-60 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 SUPERFAMILY SSF54211 260 513 1.14E-95 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 Gene3D G3DSA:3.30.70.2140 221 248 2.2E-74 T 12-10-2018 UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 Gene3D G3DSA:1.20.120.790 519 659 2.2E-37 T 12-10-2018 IPR037196 HSP90, C-terminal domain UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 660 29.897 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 Gene3D G3DSA:3.30.565.10 6 220 2.2E-74 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 PIRSF PIRSF002583 2 663 1.2E-212 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 Pfam PF00183 Hsp90 protein 194 661 8.5E-136 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 Gene3D G3DSA:3.40.50.11260 427 514 1.0E-32 T 12-10-2018 UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 Gene3D G3DSA:3.30.230.80 261 426 4.1E-64 T 12-10-2018 UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 SUPERFAMILY SSF110942 541 659 2.62E-29 T 12-10-2018 IPR037196 HSP90, C-terminal domain UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 185 2.1E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_17455 b48f6c9d44aaf0d8408f740c407ad9b8 663 SMART SM00387 28 187 3.4E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_02995 b867dcacb0bbf15515abd3147cec1750 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 1.6E-53 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UA74_02995 b867dcacb0bbf15515abd3147cec1750 122 SMART SM01374 1 122 3.1E-85 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UA74_02995 b867dcacb0bbf15515abd3147cec1750 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02995 b867dcacb0bbf15515abd3147cec1750 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.849 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UA74_02995 b867dcacb0bbf15515abd3147cec1750 122 Gene3D G3DSA:2.40.150.20 1 122 2.7E-52 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 UA74_02995 b867dcacb0bbf15515abd3147cec1750 122 SUPERFAMILY SSF50193 2 122 9.16E-50 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 UA74_02995 b867dcacb0bbf15515abd3147cec1750 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.0E-56 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 Pfam PF00005 ABC transporter 353 481 1.8E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 Pfam PF12848 ABC transporter 240 307 1.8E-8 T 12-10-2018 IPR032781 ABC-transporter extension domain UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 SMART SM00382 360 527 1.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 SMART SM00382 26 242 7.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 SUPERFAMILY SSF52540 3 239 5.24E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 Pfam PF00005 ABC transporter 18 197 3.4E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 SUPERFAMILY SSF52540 317 527 1.52E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12620 83b93327a141c6a8f8f10d1a7d309a62 542 Gene3D G3DSA:3.40.50.300 301 540 3.9E-55 T 12-10-2018 UA74_13625 1b0530e75b73297c9682fadeebe2f06b 344 SUPERFAMILY SSF53822 41 242 4.12E-6 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_13625 1b0530e75b73297c9682fadeebe2f06b 344 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 51 304 5.3E-36 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 UA74_13625 1b0530e75b73297c9682fadeebe2f06b 344 Gene3D G3DSA:3.40.50.2300 47 294 2.2E-62 T 12-10-2018 UA74_13625 1b0530e75b73297c9682fadeebe2f06b 344 Gene3D G3DSA:3.40.50.2300 139 336 2.2E-62 T 12-10-2018 UA74_19685 59c785a699ef579529b91c181328665f 153 Gene3D G3DSA:3.30.530.20 1 149 2.8E-38 T 12-10-2018 IPR023393 START-like domain superfamily UA74_19685 59c785a699ef579529b91c181328665f 153 SUPERFAMILY SSF55961 10 146 2.85E-28 T 12-10-2018 UA74_19685 59c785a699ef579529b91c181328665f 153 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 19 147 1.7E-20 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_06625 efd15005e2de46e6e26a87dc62673111 152 SUPERFAMILY SSF54593 15 143 4.91E-11 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_06625 efd15005e2de46e6e26a87dc62673111 152 Gene3D G3DSA:3.10.180.10 11 150 3.3E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_26340 3cd1b45982bbfea724d23af7ea69e1ee 250 SUPERFAMILY SSF141523 128 249 3.4E-16 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like UA74_26340 3cd1b45982bbfea724d23af7ea69e1ee 250 Gene3D G3DSA:2.40.440.10 104 250 1.1E-16 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like UA74_26340 3cd1b45982bbfea724d23af7ea69e1ee 250 Pfam PF03734 L,D-transpeptidase catalytic domain 133 249 2.1E-10 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 Gene3D G3DSA:3.40.50.720 7 442 1.4E-148 T 12-10-2018 UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 174 8.2E-14 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 PIRSF PIRSF000362 1 448 2.4E-164 T 12-10-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 Gene3D G3DSA:3.50.50.60 48 321 1.4E-148 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 1.3E-21 T 12-10-2018 UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 PRINTS PR00419 Adrenodoxin reductase family signature 31 44 1.3E-21 T 12-10-2018 UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 PRINTS PR00419 Adrenodoxin reductase family signature 74 84 1.3E-21 T 12-10-2018 UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 PRINTS PR00419 Adrenodoxin reductase family signature 145 159 1.3E-21 T 12-10-2018 UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 SUPERFAMILY SSF51971 261 439 4.71E-10 T 12-10-2018 UA74_09820 6371eaa98169cb1da1d5548963d57e66 448 SUPERFAMILY SSF51971 4 316 3.06E-60 T 12-10-2018 UA74_23090 b524142787c4f5e6f0f69b2a4f1e6bc5 211 Gene3D G3DSA:1.10.520.40 28 188 4.9E-30 T 12-10-2018 IPR038287 Cse2 superfamily UA74_23090 b524142787c4f5e6f0f69b2a4f1e6bc5 211 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 43 178 5.7E-26 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 UA74_23090 b524142787c4f5e6f0f69b2a4f1e6bc5 211 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 42 178 2.6E-17 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 UA74_18560 b8927f1383349f8dc31bcee88cc3001e 442 SUPERFAMILY SSF88946 26 97 2.98E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_18560 b8927f1383349f8dc31bcee88cc3001e 442 Pfam PF08281 Sigma-70, region 4 139 189 1.3E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_18560 b8927f1383349f8dc31bcee88cc3001e 442 Gene3D G3DSA:1.10.10.10 144 194 5.1E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18560 b8927f1383349f8dc31bcee88cc3001e 442 Gene3D G3DSA:1.10.1740.10 23 119 8.4E-7 T 12-10-2018 UA74_18560 b8927f1383349f8dc31bcee88cc3001e 442 Pfam PF04542 Sigma-70 region 2 34 100 4.9E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_18560 b8927f1383349f8dc31bcee88cc3001e 442 SUPERFAMILY SSF88659 134 191 3.49E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_07110 17055a571ab993abfbbb050a55797a40 221 Gene3D G3DSA:1.10.3720.10 3 218 3.0E-49 T 12-10-2018 IPR035906 MetI-like superfamily UA74_07110 17055a571ab993abfbbb050a55797a40 221 SUPERFAMILY SSF161098 15 201 1.7E-37 T 12-10-2018 IPR035906 MetI-like superfamily UA74_07110 17055a571ab993abfbbb050a55797a40 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 5.8E-28 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UA74_07110 17055a571ab993abfbbb050a55797a40 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 215 1.2E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_07110 17055a571ab993abfbbb050a55797a40 221 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 4 215 2.8E-85 T 12-10-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 179 1.3E-37 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 196 27.912 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 Pfam PF07499 RuvA, C-terminal domain 149 195 4.8E-9 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 Gene3D G3DSA:1.10.8.10 135 199 7.1E-18 T 12-10-2018 UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 Pfam PF14520 Helix-hairpin-helix domain 71 129 2.2E-14 T 12-10-2018 UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 Pfam PF01330 RuvA N terminal domain 1 61 7.9E-17 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 SMART SM00278 72 91 22.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 SMART SM00278 107 126 0.8 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 SUPERFAMILY SSF47781 65 132 3.34E-19 T 12-10-2018 IPR010994 RuvA domain 2-like UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 SUPERFAMILY SSF46929 148 198 3.01E-8 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 Gene3D G3DSA:2.40.50.140 1 64 7.6E-24 T 12-10-2018 UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 SUPERFAMILY SSF50249 1 62 1.26E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_11080 b74a3d7982bef4877cd344fb5e262d51 199 Gene3D G3DSA:1.10.150.20 67 132 6.8E-23 T 12-10-2018 UA74_09205 0fd1775b483f25d1d21f12d76f8dc1fa 135 Gene3D G3DSA:2.60.120.460 2 134 7.5E-28 T 12-10-2018 IPR035917 YjbQ-like superfamily UA74_09205 0fd1775b483f25d1d21f12d76f8dc1fa 135 Pfam PF01894 Uncharacterised protein family UPF0047 17 129 1.1E-21 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 UA74_09205 0fd1775b483f25d1d21f12d76f8dc1fa 135 SUPERFAMILY SSF111038 3 131 3.92E-31 T 12-10-2018 IPR035917 YjbQ-like superfamily UA74_23795 e0d4b067f8b3e71392b99b6b278fc485 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 294 3.3E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_23795 e0d4b067f8b3e71392b99b6b278fc485 301 Gene3D G3DSA:1.10.3720.10 18 292 6.1E-66 T 12-10-2018 IPR035906 MetI-like superfamily UA74_23795 e0d4b067f8b3e71392b99b6b278fc485 301 SUPERFAMILY SSF161098 25 301 4.45E-73 T 12-10-2018 IPR035906 MetI-like superfamily UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 SUPERFAMILY SSF51735 16 218 2.56E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 247 264 6.3E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 354 380 6.3E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 195 223 6.3E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 171 184 6.3E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 265 281 6.3E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 205 211 - T 12-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 PIRSF PIRSF000110 5 514 7.3E-174 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 26 513 9.4E-197 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 Gene3D G3DSA:3.40.50.720 26 203 7.5E-53 T 12-10-2018 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 SUPERFAMILY SSF55347 205 512 2.81E-110 T 12-10-2018 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 26 513 86.655 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 Gene3D G3DSA:3.30.360.10 204 513 1.2E-118 T 12-10-2018 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 30 215 9.9E-61 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_12405 72c29c80dbdcf16859f34bc826a8e9d3 514 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 217 512 9.0E-110 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UA74_17425 25104490d2782fcb671287d5a763ea1f 309 Gene3D G3DSA:3.40.190.10 88 288 5.4E-39 T 12-10-2018 UA74_17425 25104490d2782fcb671287d5a763ea1f 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 9.3E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_17425 25104490d2782fcb671287d5a763ea1f 309 Gene3D G3DSA:1.10.10.10 1 82 1.3E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17425 25104490d2782fcb671287d5a763ea1f 309 SUPERFAMILY SSF46785 1 79 1.63E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_17425 25104490d2782fcb671287d5a763ea1f 309 Gene3D G3DSA:3.40.190.10 165 270 5.4E-39 T 12-10-2018 UA74_17425 25104490d2782fcb671287d5a763ea1f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_17425 25104490d2782fcb671287d5a763ea1f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_17425 25104490d2782fcb671287d5a763ea1f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_17425 25104490d2782fcb671287d5a763ea1f 309 SUPERFAMILY SSF53850 88 298 1.03E-31 T 12-10-2018 UA74_17425 25104490d2782fcb671287d5a763ea1f 309 Pfam PF03466 LysR substrate binding domain 87 296 3.6E-30 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_07155 28b276eaabf375a73eb9a7c2f54709cf 332 SUPERFAMILY SSF82549 11 331 5.75E-122 T 12-10-2018 UA74_07155 28b276eaabf375a73eb9a7c2f54709cf 332 Gene3D G3DSA:3.30.1180.20 184 332 2.3E-50 T 12-10-2018 UA74_07155 28b276eaabf375a73eb9a7c2f54709cf 332 Gene3D G3DSA:3.40.50.10440 11 182 9.5E-67 T 12-10-2018 UA74_07155 28b276eaabf375a73eb9a7c2f54709cf 332 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 328 2.8E-142 T 12-10-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00561+2.7.1.121 UA74_07155 28b276eaabf375a73eb9a7c2f54709cf 332 Pfam PF02733 Dak1 domain 18 327 6.8E-127 T 12-10-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_06175 2dc068e1ab48c001d22f4ee7cda9fbde 191 SUPERFAMILY SSF52499 3 184 1.11E-45 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_06175 2dc068e1ab48c001d22f4ee7cda9fbde 191 Pfam PF00857 Isochorismatase family 4 184 8.7E-32 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 UA74_06175 2dc068e1ab48c001d22f4ee7cda9fbde 191 Gene3D G3DSA:3.40.50.850 2 185 3.2E-60 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_16620 bf34672adb5657459ea8da7e06eaba4b 504 Gene3D G3DSA:3.10.105.10 279 474 2.9E-31 T 12-10-2018 UA74_16620 bf34672adb5657459ea8da7e06eaba4b 504 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 409 6.9E-60 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_16620 bf34672adb5657459ea8da7e06eaba4b 504 SUPERFAMILY SSF53850 39 492 1.39E-79 T 12-10-2018 UA74_16620 bf34672adb5657459ea8da7e06eaba4b 504 Gene3D G3DSA:3.40.190.10 7 277 1.0E-37 T 12-10-2018 UA74_16620 bf34672adb5657459ea8da7e06eaba4b 504 PIRSF PIRSF002741 434 484 350.0 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_16620 bf34672adb5657459ea8da7e06eaba4b 504 PIRSF PIRSF002741 4 422 5.4E-48 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_23995 d4b2a6a26224f3be1eec8b74784a1143 345 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 38 339 2.3E-81 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 UA74_23995 d4b2a6a26224f3be1eec8b74784a1143 345 Gene3D G3DSA:3.20.20.70 33 342 9.8E-81 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_23995 d4b2a6a26224f3be1eec8b74784a1143 345 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 280 300 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 UA74_23995 d4b2a6a26224f3be1eec8b74784a1143 345 SUPERFAMILY SSF51395 33 339 1.43E-67 T 12-10-2018 UA74_23995 d4b2a6a26224f3be1eec8b74784a1143 345 Pfam PF01180 Dihydroorotate dehydrogenase 43 325 9.3E-52 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 UA74_23995 d4b2a6a26224f3be1eec8b74784a1143 345 PIRSF PIRSF000164 14 342 4.6E-64 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 UA74_23995 d4b2a6a26224f3be1eec8b74784a1143 345 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 37 343 32.816 T 12-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 UA74_28900 c705781d0c572a027a392c4c3c3bee40 425 SUPERFAMILY SSF53383 29 418 1.8E-76 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_28900 c705781d0c572a027a392c4c3c3bee40 425 Pfam PF00266 Aminotransferase class-V 101 345 6.2E-18 T 12-10-2018 IPR000192 Aminotransferase class V domain UA74_28900 c705781d0c572a027a392c4c3c3bee40 425 Hamap MF_01970 Kynureninase [kynU]. 18 417 31.865 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 UA74_28900 c705781d0c572a027a392c4c3c3bee40 425 Gene3D G3DSA:3.40.640.10 64 322 9.7E-132 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_28900 c705781d0c572a027a392c4c3c3bee40 425 Gene3D G3DSA:3.90.1150.10 33 416 9.7E-132 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_28900 c705781d0c572a027a392c4c3c3bee40 425 PIRSF PIRSF038800 22 423 1.1E-119 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 UA74_19495 e1d5c5634e0a70f6e80e72d830332b20 457 Gene3D G3DSA:3.50.50.60 2 406 3.8E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_19495 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.4E-7 T 12-10-2018 UA74_19495 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 197 222 7.4E-7 T 12-10-2018 UA74_19495 e1d5c5634e0a70f6e80e72d830332b20 457 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 330 2.0E-11 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_19495 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 304 320 3.8E-8 T 12-10-2018 UA74_19495 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.8E-8 T 12-10-2018 UA74_19495 e1d5c5634e0a70f6e80e72d830332b20 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 197 215 3.8E-8 T 12-10-2018 UA74_19495 e1d5c5634e0a70f6e80e72d830332b20 457 SUPERFAMILY SSF51905 3 220 1.11E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_19495 e1d5c5634e0a70f6e80e72d830332b20 457 SUPERFAMILY SSF51905 186 398 7.34E-8 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06675 8f96a74679dabeb4c90975fc0546b36f 658 Pfam PF03703 Bacterial PH domain 185 266 5.9E-17 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_06675 8f96a74679dabeb4c90975fc0546b36f 658 Pfam PF03703 Bacterial PH domain 542 614 8.1E-7 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_02030 22305107d7d5cd2f0fdc7cc3aaf1ece7 118 Gene3D G3DSA:1.10.260.40 12 78 7.8E-18 T 12-10-2018 UA74_02030 22305107d7d5cd2f0fdc7cc3aaf1ece7 118 SUPERFAMILY SSF47413 13 75 6.19E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_02030 22305107d7d5cd2f0fdc7cc3aaf1ece7 118 Pfam PF01381 Helix-turn-helix 19 71 4.9E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_02030 22305107d7d5cd2f0fdc7cc3aaf1ece7 118 SMART SM00530 18 73 7.8E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_18780 b9985912a98dfa31e6d4be0e5d7b917b 410 SMART SM00922 129 265 1.1E-17 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_18780 b9985912a98dfa31e6d4be0e5d7b917b 410 Gene3D G3DSA:3.20.20.120 105 376 3.9E-159 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_18780 b9985912a98dfa31e6d4be0e5d7b917b 410 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 5.8E-31 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_18780 b9985912a98dfa31e6d4be0e5d7b917b 410 SUPERFAMILY SSF54826 1 112 3.68E-31 T 12-10-2018 UA74_18780 b9985912a98dfa31e6d4be0e5d7b917b 410 Pfam PF13378 Enolase C-terminal domain-like 201 385 7.9E-41 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_18780 b9985912a98dfa31e6d4be0e5d7b917b 410 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_18780 b9985912a98dfa31e6d4be0e5d7b917b 410 Gene3D G3DSA:3.30.390.10 3 407 3.9E-159 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_18780 b9985912a98dfa31e6d4be0e5d7b917b 410 SUPERFAMILY SSF51604 98 394 7.75E-71 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_15240 ff3fdb961145806cc0bf9fc738f7cf65 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 57 4.8E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_15240 ff3fdb961145806cc0bf9fc738f7cf65 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 7.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_15240 ff3fdb961145806cc0bf9fc738f7cf65 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 7.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_15240 ff3fdb961145806cc0bf9fc738f7cf65 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 7.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_15240 ff3fdb961145806cc0bf9fc738f7cf65 293 Gene3D G3DSA:3.40.190.290 85 287 8.9E-49 T 12-10-2018 UA74_15240 ff3fdb961145806cc0bf9fc738f7cf65 293 SUPERFAMILY SSF53850 83 282 2.96E-39 T 12-10-2018 UA74_15240 ff3fdb961145806cc0bf9fc738f7cf65 293 SUPERFAMILY SSF46785 1 78 4.04E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_15240 ff3fdb961145806cc0bf9fc738f7cf65 293 Pfam PF03466 LysR substrate binding domain 83 282 3.7E-43 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_15240 ff3fdb961145806cc0bf9fc738f7cf65 293 Gene3D G3DSA:1.10.10.10 1 79 1.0E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_01350 70b7c6a1dedba1f3cda1ec00b4be7427 165 Pfam PF12079 Protein of unknown function (DUF3558) 5 159 3.0E-20 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_19410 da6a0d569abbb6960ce45931df5353f6 96 Gene3D G3DSA:3.30.70.100 2 91 1.3E-11 T 12-10-2018 UA74_19410 da6a0d569abbb6960ce45931df5353f6 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 69 7.3E-10 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_19410 da6a0d569abbb6960ce45931df5353f6 96 SUPERFAMILY SSF54909 1 69 2.64E-14 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_02110 eb62d6456eda2cf7d47fec7da5ef7dc7 216 Gene3D G3DSA:3.90.79.10 2 169 8.7E-24 T 12-10-2018 UA74_02110 eb62d6456eda2cf7d47fec7da5ef7dc7 216 SUPERFAMILY SSF55811 5 155 9.07E-18 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_02110 eb62d6456eda2cf7d47fec7da5ef7dc7 216 Pfam PF00293 NUDIX domain 28 154 2.1E-9 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_23230 a38bf0afdff5f0fbd53eec2818ef0539 130 Gene3D G3DSA:2.30.110.10 1 126 5.3E-33 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_23230 a38bf0afdff5f0fbd53eec2818ef0539 130 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 83 9.7E-17 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_23230 a38bf0afdff5f0fbd53eec2818ef0539 130 SUPERFAMILY SSF50475 7 125 2.29E-27 T 12-10-2018 UA74_16050 f917309e1660af0a9f77132287dd0750 590 SUPERFAMILY SSF52374 116 464 2.67E-85 T 12-10-2018 UA74_16050 f917309e1660af0a9f77132287dd0750 590 Hamap MF_00123 Arginine--tRNA ligase [argS]. 13 590 25.595 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_16050 f917309e1660af0a9f77132287dd0750 590 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 13 92 2.3E-15 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_16050 f917309e1660af0a9f77132287dd0750 590 Pfam PF05746 DALR anticodon binding domain 472 590 3.1E-32 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_16050 f917309e1660af0a9f77132287dd0750 590 Gene3D G3DSA:3.30.1360.70 6 111 6.2E-17 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_16050 f917309e1660af0a9f77132287dd0750 590 Gene3D G3DSA:3.40.50.620 115 465 4.8E-102 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_16050 f917309e1660af0a9f77132287dd0750 590 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 14 590 5.1E-146 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_16050 f917309e1660af0a9f77132287dd0750 590 SMART SM01016 13 92 9.4E-22 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_16050 f917309e1660af0a9f77132287dd0750 590 SUPERFAMILY SSF55190 17 102 1.7E-13 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_16050 f917309e1660af0a9f77132287dd0750 590 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 128 139 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_16050 f917309e1660af0a9f77132287dd0750 590 Gene3D G3DSA:1.10.730.10 466 590 2.4E-34 T 12-10-2018 UA74_16050 f917309e1660af0a9f77132287dd0750 590 Pfam PF00750 tRNA synthetases class I (R) 119 457 1.6E-114 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 UA74_16050 f917309e1660af0a9f77132287dd0750 590 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 135 6.2E-26 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_16050 f917309e1660af0a9f77132287dd0750 590 PRINTS PR01038 Arginyl-tRNA synthetase signature 315 336 6.2E-26 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_16050 f917309e1660af0a9f77132287dd0750 590 PRINTS PR01038 Arginyl-tRNA synthetase signature 159 172 6.2E-26 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_16050 f917309e1660af0a9f77132287dd0750 590 PRINTS PR01038 Arginyl-tRNA synthetase signature 135 151 6.2E-26 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_16050 f917309e1660af0a9f77132287dd0750 590 SUPERFAMILY SSF47323 466 590 1.05E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_16050 f917309e1660af0a9f77132287dd0750 590 SMART SM00836 472 590 3.6E-38 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_18060 630b1beec53488afa57a78c5cf11622c 741 Pfam PF03176 MMPL family 498 701 5.5E-25 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UA74_18060 630b1beec53488afa57a78c5cf11622c 741 Pfam PF03176 MMPL family 45 362 6.6E-45 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UA74_18060 630b1beec53488afa57a78c5cf11622c 741 SUPERFAMILY SSF82866 141 337 3.4E-31 T 12-10-2018 UA74_18060 630b1beec53488afa57a78c5cf11622c 741 SUPERFAMILY SSF82866 462 700 6.15E-23 T 12-10-2018 UA74_08975 d9785c6878e90df36c42b054d6203c5b 161 Pfam PF00484 Carbonic anhydrase 31 119 1.9E-12 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_08975 d9785c6878e90df36c42b054d6203c5b 161 Gene3D G3DSA:3.40.1050.10 1 161 1.9E-61 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UA74_08975 d9785c6878e90df36c42b054d6203c5b 161 SUPERFAMILY SSF53056 2 160 1.83E-35 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UA74_08975 d9785c6878e90df36c42b054d6203c5b 161 SMART SM00947 23 161 2.7E-27 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_17875 4143f90653450e77628ab03488d46fdd 1404 Gene3D G3DSA:2.60.120.260 852 996 8.1E-23 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_17875 4143f90653450e77628ab03488d46fdd 1404 Gene3D G3DSA:2.60.120.260 1100 1250 1.6E-34 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_17875 4143f90653450e77628ab03488d46fdd 1404 Gene3D G3DSA:1.50.10.10 386 624 1.0E-9 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_17875 4143f90653450e77628ab03488d46fdd 1404 Gene3D G3DSA:2.60.40.10 1008 1099 1.4E-10 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_17875 4143f90653450e77628ab03488d46fdd 1404 SUPERFAMILY SSF49785 1101 1246 3.83E-5 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_17875 4143f90653450e77628ab03488d46fdd 1404 SUPERFAMILY SSF49785 855 996 5.72E-10 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_17875 4143f90653450e77628ab03488d46fdd 1404 SUPERFAMILY SSF48208 316 780 5.35E-23 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_17875 4143f90653450e77628ab03488d46fdd 1404 Pfam PF07532 Bacterial Ig-like domain (group 4) 1334 1392 2.1E-13 T 12-10-2018 IPR011081 Bacterial Ig-related UA74_17875 4143f90653450e77628ab03488d46fdd 1404 Pfam PF00754 F5/8 type C domain 866 988 4.8E-12 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_23220 827f95dc6a2ae53a883372278633efe1 448 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 218 232 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_23220 827f95dc6a2ae53a883372278633efe1 448 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 25 441 1.8E-139 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_23220 827f95dc6a2ae53a883372278633efe1 448 Gene3D G3DSA:3.90.1150.10 310 448 3.2E-49 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_23220 827f95dc6a2ae53a883372278633efe1 448 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 24 441 8.2E-197 T 12-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 UA74_23220 827f95dc6a2ae53a883372278633efe1 448 PIRSF PIRSF001434 13 445 2.8E-129 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UA74_23220 827f95dc6a2ae53a883372278633efe1 448 Gene3D G3DSA:3.40.640.10 23 306 2.8E-104 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_23220 827f95dc6a2ae53a883372278633efe1 448 SUPERFAMILY SSF53383 22 441 2.82E-120 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 Pfam PF00106 short chain dehydrogenase 22 214 2.1E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 Gene3D G3DSA:3.40.50.720 17 254 8.4E-63 T 12-10-2018 UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 SUPERFAMILY SSF51735 20 240 4.23E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 8.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 8.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 8.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 8.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 8.9E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 197 7.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 7.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15390 7b688d26b0e61f5017b6a2c87a17d7e5 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 7.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 SUPERFAMILY SSF51735 4 184 4.87E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 2.2E-62 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 330 44.89 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 Gene3D G3DSA:3.40.50.720 1 183 1.2E-78 T 12-10-2018 UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 179 6.5E-75 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 SUPERFAMILY SSF48179 185 330 3.74E-66 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 1.5E-131 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 PIRSF PIRSF000116 1 210 3.2E-40 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 PIRSF PIRSF000116 204 334 1.2E-13 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UA74_25930 d1e225ed88b43b7ae3884a138cca7607 337 Gene3D G3DSA:1.10.3730.40 184 337 2.2E-69 T 12-10-2018 UA74_14930 3f6d9bd06bdd57c3ebc1390361f29d8d 197 Pfam PF07931 Chloramphenicol phosphotransferase-like protein 18 183 4.2E-10 T 12-10-2018 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 UA74_14930 3f6d9bd06bdd57c3ebc1390361f29d8d 197 SUPERFAMILY SSF52540 15 182 1.94E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14930 3f6d9bd06bdd57c3ebc1390361f29d8d 197 Gene3D G3DSA:3.40.50.300 12 189 3.4E-41 T 12-10-2018 UA74_29460 941d837cc336c9fe5c9c1d147be424c8 344 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_29460 941d837cc336c9fe5c9c1d147be424c8 344 PIRSF PIRSF001359 6 341 7.5E-66 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_29460 941d837cc336c9fe5c9c1d147be424c8 344 SUPERFAMILY SSF51569 4 340 2.56E-98 T 12-10-2018 UA74_29460 941d837cc336c9fe5c9c1d147be424c8 344 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 340 6.8E-81 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_29460 941d837cc336c9fe5c9c1d147be424c8 344 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_29460 941d837cc336c9fe5c9c1d147be424c8 344 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 339 1.5E-142 T 12-10-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 UA74_29460 941d837cc336c9fe5c9c1d147be424c8 344 Gene3D G3DSA:3.20.20.70 1 344 2.2E-128 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_29460 941d837cc336c9fe5c9c1d147be424c8 344 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 340 5.9E-76 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_00015 9f598af95aa790409b6fca402e0565be 306 Gene3D G3DSA:1.10.1040.10 162 292 1.3E-47 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_00015 9f598af95aa790409b6fca402e0565be 306 SUPERFAMILY SSF51735 2 143 5.8E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_00015 9f598af95aa790409b6fca402e0565be 306 Gene3D G3DSA:3.40.50.720 1 161 1.8E-41 T 12-10-2018 UA74_00015 9f598af95aa790409b6fca402e0565be 306 SMART SM01350 162 305 1.7E-4 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_00015 9f598af95aa790409b6fca402e0565be 306 SUPERFAMILY SSF48179 160 292 2.31E-40 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 5.6E-33 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 5.6E-33 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 5.6E-33 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 151 179 5.6E-33 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_00015 9f598af95aa790409b6fca402e0565be 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 226 253 5.6E-33 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_00015 9f598af95aa790409b6fca402e0565be 306 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 2 292 2.6E-105 T 12-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 UA74_00015 9f598af95aa790409b6fca402e0565be 306 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 230 242 - T 12-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_00015 9f598af95aa790409b6fca402e0565be 306 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 143 1.7E-33 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UA74_00015 9f598af95aa790409b6fca402e0565be 306 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 162 272 1.5E-22 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 310 319 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00359 B-class P450 signature 158 180 7.6E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00359 B-class P450 signature 121 136 7.6E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00359 B-class P450 signature 317 328 7.6E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00359 B-class P450 signature 54 65 7.6E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00359 B-class P450 signature 258 285 7.6E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00359 B-class P450 signature 308 317 7.6E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00359 B-class P450 signature 240 251 7.6E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00359 B-class P450 signature 104 120 7.6E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 Gene3D G3DSA:1.10.630.10 1 371 9.9E-126 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 SUPERFAMILY SSF48264 2 369 1.83E-86 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00385 P450 superfamily signature 317 328 9.7E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00385 P450 superfamily signature 308 317 9.7E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00385 P450 superfamily signature 205 222 9.7E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 PRINTS PR00385 P450 superfamily signature 240 251 9.7E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 Pfam PF00067 Cytochrome P450 171 232 1.5E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20305 14684ae5b38192a92a525efdf46cee00 373 Pfam PF00067 Cytochrome P450 239 338 8.4E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 SUPERFAMILY SSF55326 41 223 7.92E-49 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 Pfam PF02769 AIR synthase related protein, C-terminal domain 233 388 8.3E-32 T 12-10-2018 IPR010918 PurM-like, C-terminal domain UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 Pfam PF02769 AIR synthase related protein, C-terminal domain 621 758 1.1E-16 T 12-10-2018 IPR010918 PurM-like, C-terminal domain UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 Pfam PF00586 AIR synthase related protein, N-terminal domain 488 606 1.7E-24 T 12-10-2018 IPR016188 PurM-like, N-terminal domain UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 Pfam PF00586 AIR synthase related protein, N-terminal domain 118 219 4.1E-22 T 12-10-2018 IPR016188 PurM-like, N-terminal domain UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 SUPERFAMILY SSF55326 444 613 2.62E-57 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 PIRSF PIRSF001587 26 786 4.9E-279 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 45 782 2.1E-247 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 Gene3D G3DSA:3.30.1330.10 70 224 7.9E-123 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 Gene3D G3DSA:3.90.650.10 56 409 7.9E-123 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 786 305.441 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 SUPERFAMILY SSF56042 620 785 2.99E-35 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 Gene3D G3DSA:3.90.650.10 618 785 2.3E-35 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 SUPERFAMILY SSF56042 232 473 4.93E-50 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UA74_29250 7a1fb67a76dd365073aa2c5bd1b31666 786 Gene3D G3DSA:3.30.1330.10 436 609 1.1E-58 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UA74_29940 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 2.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29940 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 2.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29940 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 2.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29940 043af488de98637d7a3e5608e7aa4108 228 Gene3D G3DSA:3.40.50.720 3 228 3.6E-60 T 12-10-2018 UA74_29940 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29940 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29940 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29940 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29940 043af488de98637d7a3e5608e7aa4108 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29940 043af488de98637d7a3e5608e7aa4108 228 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_29940 043af488de98637d7a3e5608e7aa4108 228 SUPERFAMILY SSF51735 6 215 3.5E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_29940 043af488de98637d7a3e5608e7aa4108 228 Pfam PF00106 short chain dehydrogenase 7 188 5.9E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29940 043af488de98637d7a3e5608e7aa4108 228 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 206 6.6E-4 T 12-10-2018 UA74_10070 0c12290fddfb1ac6d7292089f447a082 240 Pfam PF01553 Acyltransferase 45 167 1.2E-21 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_10070 0c12290fddfb1ac6d7292089f447a082 240 SUPERFAMILY SSF69593 35 227 1.96E-35 T 12-10-2018 UA74_10070 0c12290fddfb1ac6d7292089f447a082 240 SMART SM00563 60 170 5.4E-31 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_21025 c1b8cded4e7207ca1aef9b6197dbe74e 457 Pfam PF00480 ROK family 13 211 8.6E-9 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_21025 c1b8cded4e7207ca1aef9b6197dbe74e 457 SUPERFAMILY SSF53067 11 439 7.98E-19 T 12-10-2018 UA74_21025 c1b8cded4e7207ca1aef9b6197dbe74e 457 Gene3D G3DSA:3.30.420.40 9 140 5.9E-11 T 12-10-2018 UA74_19505 203bbdbe0ea5f49c1f5fa3489d9d8887 138 SUPERFAMILY SSF46955 1 112 8.06E-26 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_19505 203bbdbe0ea5f49c1f5fa3489d9d8887 138 Gene3D G3DSA:1.10.1660.10 1 126 2.5E-30 T 12-10-2018 UA74_19505 203bbdbe0ea5f49c1f5fa3489d9d8887 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.8E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_19505 203bbdbe0ea5f49c1f5fa3489d9d8887 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 7.8E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_19505 203bbdbe0ea5f49c1f5fa3489d9d8887 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.8E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_19505 203bbdbe0ea5f49c1f5fa3489d9d8887 138 Pfam PF13411 MerR HTH family regulatory protein 1 61 6.2E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_19505 203bbdbe0ea5f49c1f5fa3489d9d8887 138 SMART SM00422 1 69 1.0E-21 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 Gene3D G3DSA:3.30.70.100 3 86 6.5E-18 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 665 677 6.0E-26 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 292 306 6.0E-26 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 567 578 6.0E-26 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 589 599 6.0E-26 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 661 6.0E-26 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 442 456 6.0E-26 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 164 744 1.8E-172 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 217 721 4.8E-82 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 Pfam PF00403 Heavy-metal-associated domain 19 75 4.4E-10 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF56784 440 742 1.65E-53 T 12-10-2018 IPR036412 HAD-like superfamily UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 193 210 7.2E-6 T 12-10-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 91 109 7.2E-6 T 12-10-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 245 264 7.2E-6 T 12-10-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 PRINTS PR00940 Cation-transporting P-type ATPase A signature 109 126 7.2E-6 T 12-10-2018 IPR000579 Cation-transporting P-type ATPase A/B GO:0006812|GO:0016021|GO:0019829 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF81665 93 434 5.75E-13 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 Pfam PF00122 E1-E2 ATPase 243 420 1.1E-50 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 Gene3D G3DSA:3.40.1110.10 453 574 1.3E-86 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 207 745 9.8E-148 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 ProSitePatterns PS01047 Heavy-metal-associated domain. 19 47 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 Gene3D G3DSA:2.70.150.20 235 347 7.4E-30 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF55008 11 81 2.75E-18 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 Pfam PF00702 haloacid dehalogenase-like hydrolase 438 656 1.9E-45 T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 SUPERFAMILY SSF81653 247 339 2.48E-22 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 ProSitePatterns PS01229 Hypothetical cof family signature 2. 642 664 - T 12-10-2018 UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 Gene3D G3DSA:3.40.50.1000 423 694 1.3E-86 T 12-10-2018 IPR023214 HAD superfamily UA74_17210 3e29095bf9fb1b49d1325e85a0dba9a3 761 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 444 450 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 Pfam PF00067 Cytochrome P450 40 385 2.2E-34 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00385 P450 superfamily signature 355 364 7.0E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00385 P450 superfamily signature 288 299 7.0E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00385 P450 superfamily signature 253 270 7.0E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00385 P450 superfamily signature 364 375 7.0E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00359 B-class P450 signature 306 333 1.3E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00359 B-class P450 signature 288 299 1.3E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00359 B-class P450 signature 364 375 1.3E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00359 B-class P450 signature 149 165 1.3E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00359 B-class P450 signature 204 226 1.3E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00359 B-class P450 signature 355 364 1.3E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00359 B-class P450 signature 102 113 1.3E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00359 B-class P450 signature 334 349 1.3E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 PRINTS PR00359 B-class P450 signature 166 181 1.3E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 SUPERFAMILY SSF48264 31 415 4.98E-97 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 Gene3D G3DSA:1.10.630.10 20 416 1.8E-124 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12700 d62867fce916df9c084796ec64e41dfa 416 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 357 366 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_02155 d24db47b83c8124acbea9e05a2bd224b 207 SUPERFAMILY SSF46689 13 93 1.51E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_02155 d24db47b83c8124acbea9e05a2bd224b 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 5.5E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_02155 d24db47b83c8124acbea9e05a2bd224b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_02155 d24db47b83c8124acbea9e05a2bd224b 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_02155 d24db47b83c8124acbea9e05a2bd224b 207 SUPERFAMILY SSF48498 92 202 2.56E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_02155 d24db47b83c8124acbea9e05a2bd224b 207 Gene3D G3DSA:1.10.357.10 9 206 5.9E-55 T 12-10-2018 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 14 492 1.4E-142 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 Pfam PF02637 GatB domain 351 493 5.9E-39 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 SUPERFAMILY SSF89095 350 493 3.66E-25 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 13 497 35.336 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 Pfam PF02934 GatB/GatE catalytic domain 17 311 1.2E-105 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 SUPERFAMILY SSF55931 16 318 1.37E-111 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 162 176 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 SMART SM00845 349 496 7.8E-54 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 Gene3D G3DSA:1.10.150.380 319 434 2.6E-18 T 12-10-2018 UA74_26020 c0d33a57a66d0d50f5ba13d3d6eb0520 500 Gene3D G3DSA:1.10.10.410 436 495 9.5E-15 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal UA74_05770 186df5f524e9aff641ae1d6fc1fb4767 184 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 8 75 4.8E-6 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_05770 186df5f524e9aff641ae1d6fc1fb4767 184 SUPERFAMILY SSF56214 8 77 4.01E-8 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_05770 186df5f524e9aff641ae1d6fc1fb4767 184 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 11 75 9.0E-5 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UA74_05770 186df5f524e9aff641ae1d6fc1fb4767 184 Gene3D G3DSA:3.90.470.20 5 128 1.6E-8 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_04365 d132ef1785e28f184b323a4c6208a9a2 650 Gene3D G3DSA:3.90.76.10 145 251 1.5E-176 T 12-10-2018 UA74_04365 d132ef1785e28f184b323a4c6208a9a2 650 Gene3D G3DSA:3.40.190.10 113 629 1.5E-176 T 12-10-2018 UA74_04365 d132ef1785e28f184b323a4c6208a9a2 650 Gene3D G3DSA:3.10.105.10 359 617 1.5E-176 T 12-10-2018 UA74_04365 d132ef1785e28f184b323a4c6208a9a2 650 SUPERFAMILY SSF53850 112 644 6.7E-60 T 12-10-2018 UA74_04365 d132ef1785e28f184b323a4c6208a9a2 650 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 169 508 4.0E-35 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_10470 92222d826c42b9b8dfef46690f7afe61 503 Pfam PF00916 Sulfate permease family 178 369 9.0E-27 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 UA74_10470 92222d826c42b9b8dfef46690f7afe61 503 Pfam PF00916 Sulfate permease family 31 154 2.6E-20 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 UA74_10470 92222d826c42b9b8dfef46690f7afe61 503 SUPERFAMILY SSF52091 410 491 3.73E-13 T 12-10-2018 IPR036513 STAS domain superfamily UA74_10470 92222d826c42b9b8dfef46690f7afe61 503 Pfam PF01740 STAS domain 414 491 9.7E-8 T 12-10-2018 IPR002645 STAS domain UA74_10470 92222d826c42b9b8dfef46690f7afe61 503 Gene3D G3DSA:3.30.750.24 401 496 2.0E-28 T 12-10-2018 IPR036513 STAS domain superfamily UA74_26415 d09a616194a1218cc50d27cfa6c9242f 307 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 117 3.3E-26 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_26415 d09a616194a1218cc50d27cfa6c9242f 307 Gene3D G3DSA:3.40.50.10330 1 125 1.1E-31 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 UA74_26415 d09a616194a1218cc50d27cfa6c9242f 307 SUPERFAMILY SSF111331 2 306 1.44E-57 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily UA74_26415 d09a616194a1218cc50d27cfa6c9242f 307 Gene3D G3DSA:2.60.200.40 128 300 7.2E-19 T 12-10-2018 UA74_26415 d09a616194a1218cc50d27cfa6c9242f 307 SMART SM00046 2 131 1.8E-14 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_06370 a331530338c3f2753256e41485f580e0 363 SUPERFAMILY SSF53335 75 355 4.67E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_06370 a331530338c3f2753256e41485f580e0 363 Gene3D G3DSA:3.40.50.150 41 315 1.6E-34 T 12-10-2018 UA74_06370 a331530338c3f2753256e41485f580e0 363 Pfam PF08241 Methyltransferase domain 114 211 7.2E-23 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_14640 ad3b78853607f9ac87ad839db75a29ac 250 SUPERFAMILY SSF53335 28 249 4.22E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_14640 ad3b78853607f9ac87ad839db75a29ac 250 Pfam PF08241 Methyltransferase domain 53 139 3.8E-9 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_14640 ad3b78853607f9ac87ad839db75a29ac 250 Gene3D G3DSA:3.40.50.150 2 249 9.7E-18 T 12-10-2018 UA74_02650 39a56ff08f01f7872305d8b648445d88 637 SUPERFAMILY SSF52922 533 630 1.88E-10 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_02650 39a56ff08f01f7872305d8b648445d88 637 Gene3D G3DSA:3.40.920.10 26 232 2.7E-16 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 UA74_02650 39a56ff08f01f7872305d8b648445d88 637 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 276 493 1.3E-52 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 UA74_02650 39a56ff08f01f7872305d8b648445d88 637 Gene3D G3DSA:3.40.50.970 239 441 8.6E-63 T 12-10-2018 UA74_02650 39a56ff08f01f7872305d8b648445d88 637 SUPERFAMILY SSF53323 32 244 4.58E-17 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 UA74_02650 39a56ff08f01f7872305d8b648445d88 637 Gene3D G3DSA:3.40.50.920 528 633 2.9E-16 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_02650 39a56ff08f01f7872305d8b648445d88 637 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 38 226 1.1E-26 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 UA74_02650 39a56ff08f01f7872305d8b648445d88 637 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 30 626 1.8E-196 T 12-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 UA74_02650 39a56ff08f01f7872305d8b648445d88 637 SUPERFAMILY SSF52518 250 516 1.42E-60 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_05215 0f83cd7119e020d3a0cd8446653bcaaa 498 SUPERFAMILY SSF56801 2 497 2.62E-105 T 12-10-2018 UA74_05215 0f83cd7119e020d3a0cd8446653bcaaa 498 Gene3D G3DSA:3.40.50.12780 5 403 8.9E-88 T 12-10-2018 UA74_05215 0f83cd7119e020d3a0cd8446653bcaaa 498 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 489 1.1E-5 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_05215 0f83cd7119e020d3a0cd8446653bcaaa 498 ProSitePatterns PS00455 Putative AMP-binding domain signature. 153 164 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_05215 0f83cd7119e020d3a0cd8446653bcaaa 498 Pfam PF00501 AMP-binding enzyme 8 408 2.1E-63 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_05215 0f83cd7119e020d3a0cd8446653bcaaa 498 Gene3D G3DSA:3.30.300.30 404 498 2.9E-24 T 12-10-2018 UA74_10165 10a8e37ce9fda5fb557c57c54503670c 432 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 243 274 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_10165 10a8e37ce9fda5fb557c57c54503670c 432 SUPERFAMILY SSF51604 182 428 5.63E-69 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_10165 10a8e37ce9fda5fb557c57c54503670c 432 Gene3D G3DSA:3.20.20.120 130 431 4.0E-109 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_10165 10a8e37ce9fda5fb557c57c54503670c 432 Gene3D G3DSA:3.30.390.10 1 129 1.0E-51 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_10165 10a8e37ce9fda5fb557c57c54503670c 432 SUPERFAMILY SSF54826 3 136 1.68E-38 T 12-10-2018 UA74_10165 10a8e37ce9fda5fb557c57c54503670c 432 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 39 134 4.2E-8 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_10165 10a8e37ce9fda5fb557c57c54503670c 432 Pfam PF13378 Enolase C-terminal domain-like 203 414 2.1E-62 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_10165 10a8e37ce9fda5fb557c57c54503670c 432 SMART SM00922 197 293 4.7E-27 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_17700 1c61d2911bf1acc6bfc3d807d0f4624e 249 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 218 1.2E-57 T 12-10-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 UA74_17700 1c61d2911bf1acc6bfc3d807d0f4624e 249 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 45 1.7E-12 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_17700 1c61d2911bf1acc6bfc3d807d0f4624e 249 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 182 3.9E-45 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_06195 52cb754d4348a9c4190903c53e30dd1c 424 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 1 408 7.8E-126 T 12-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 UA74_06195 52cb754d4348a9c4190903c53e30dd1c 424 SUPERFAMILY SSF51690 130 419 1.35E-83 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 UA74_06195 52cb754d4348a9c4190903c53e30dd1c 424 Gene3D G3DSA:3.20.140.10 1 407 6.0E-99 T 12-10-2018 UA74_06195 52cb754d4348a9c4190903c53e30dd1c 424 Gene3D G3DSA:3.20.20.70 142 301 6.0E-99 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_06195 52cb754d4348a9c4190903c53e30dd1c 424 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 130 299 2.9E-6 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 UA74_06195 52cb754d4348a9c4190903c53e30dd1c 424 SUPERFAMILY SSF54675 1 127 6.87E-38 T 12-10-2018 UA74_06195 52cb754d4348a9c4190903c53e30dd1c 424 PIRSF PIRSF000484 1 420 5.3E-94 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 UA74_24160 39453a69a8331f3fe5e9199416615a7f 339 SUPERFAMILY SSF47413 7 63 5.23E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_24160 39453a69a8331f3fe5e9199416615a7f 339 Gene3D G3DSA:1.10.260.40 7 64 5.1E-22 T 12-10-2018 UA74_24160 39453a69a8331f3fe5e9199416615a7f 339 Pfam PF13377 Periplasmic binding protein-like domain 174 332 5.8E-39 T 12-10-2018 UA74_24160 39453a69a8331f3fe5e9199416615a7f 339 SMART SM00354 7 77 6.7E-26 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_24160 39453a69a8331f3fe5e9199416615a7f 339 SUPERFAMILY SSF53822 66 336 1.59E-53 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_24160 39453a69a8331f3fe5e9199416615a7f 339 Gene3D G3DSA:3.40.50.2300 83 323 1.1E-64 T 12-10-2018 UA74_24160 39453a69a8331f3fe5e9199416615a7f 339 Gene3D G3DSA:3.40.50.2300 165 327 1.1E-64 T 12-10-2018 UA74_24160 39453a69a8331f3fe5e9199416615a7f 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 54 2.1E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_22330 ceea03abfec385e360e66328b2b801e1 445 Gene3D G3DSA:3.40.50.1820 2 269 2.3E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22330 ceea03abfec385e360e66328b2b801e1 445 Pfam PF12697 Alpha/beta hydrolase family 26 256 2.3E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22330 ceea03abfec385e360e66328b2b801e1 445 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 368 425 8.0E-16 T 12-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal UA74_22330 ceea03abfec385e360e66328b2b801e1 445 SUPERFAMILY SSF53474 1 263 4.36E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22330 ceea03abfec385e360e66328b2b801e1 445 SUPERFAMILY SSF50249 320 432 7.2E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_22330 ceea03abfec385e360e66328b2b801e1 445 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 333 366 9.1E-9 T 12-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal UA74_06805 c442e1ba82f33e8398df9e15c74d3a7d 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 46 2.6E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06805 c442e1ba82f33e8398df9e15c74d3a7d 184 Pfam PF16925 Bacterial transcriptional repressor C-terminal 86 179 2.3E-7 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_06805 c442e1ba82f33e8398df9e15c74d3a7d 184 Gene3D G3DSA:1.10.10.60 1 54 9.3E-17 T 12-10-2018 UA74_06805 c442e1ba82f33e8398df9e15c74d3a7d 184 Gene3D G3DSA:1.10.357.10 55 181 6.2E-24 T 12-10-2018 UA74_06805 c442e1ba82f33e8398df9e15c74d3a7d 184 SUPERFAMILY SSF46689 2 70 2.92E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_06805 c442e1ba82f33e8398df9e15c74d3a7d 184 ProSitePatterns PS01081 TetR-type HTH domain signature. 12 42 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_06805 c442e1ba82f33e8398df9e15c74d3a7d 184 SUPERFAMILY SSF48498 67 180 2.88E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_03395 61dab505ff67f3f759fd2817ba83bc85 427 Gene3D G3DSA:3.40.50.1820 37 422 6.8E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_03395 61dab505ff67f3f759fd2817ba83bc85 427 SUPERFAMILY SSF53474 42 419 3.94E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_03395 61dab505ff67f3f759fd2817ba83bc85 427 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 51 59 2.6E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_03395 61dab505ff67f3f759fd2817ba83bc85 427 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 140 154 2.6E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_03395 61dab505ff67f3f759fd2817ba83bc85 427 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 81 92 2.6E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_03395 61dab505ff67f3f759fd2817ba83bc85 427 Pfam PF00561 alpha/beta hydrolase fold 49 231 2.0E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05890 76940bc54ea0f879ffa2b75869811cd8 200 Pfam PF12464 Maltose acetyltransferase 24 74 2.1E-6 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 UA74_05890 76940bc54ea0f879ffa2b75869811cd8 200 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 155 183 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 UA74_05890 76940bc54ea0f879ffa2b75869811cd8 200 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 147 181 2.8E-9 T 12-10-2018 IPR001451 Hexapeptide repeat UA74_05890 76940bc54ea0f879ffa2b75869811cd8 200 SUPERFAMILY SSF51161 33 198 3.47E-46 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily UA74_05890 76940bc54ea0f879ffa2b75869811cd8 200 Gene3D G3DSA:2.160.10.10 19 200 1.9E-57 T 12-10-2018 UA74_05890 76940bc54ea0f879ffa2b75869811cd8 200 SMART SM01266 22 75 9.5E-8 T 12-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 UA74_07505 9a7db41a6b3148cb2d3b8276188fa8a8 580 Pfam PF16657 Maltogenic Amylase, C-terminal domain 488 570 8.6E-22 T 12-10-2018 IPR032091 Maltogenic Amylase, C-terminal UA74_07505 9a7db41a6b3148cb2d3b8276188fa8a8 580 Gene3D G3DSA:2.60.40.1180 488 580 1.6E-32 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_07505 9a7db41a6b3148cb2d3b8276188fa8a8 580 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 30 573 8.4E-288 T 12-10-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622|MetaCyc: PWY-7900 UA74_07505 9a7db41a6b3148cb2d3b8276188fa8a8 580 Pfam PF00128 Alpha amylase, catalytic domain 53 409 7.4E-75 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07505 9a7db41a6b3148cb2d3b8276188fa8a8 580 Gene3D G3DSA:3.20.20.80 30 483 6.0E-226 T 12-10-2018 UA74_07505 9a7db41a6b3148cb2d3b8276188fa8a8 580 SUPERFAMILY SSF51011 492 573 3.15E-15 T 12-10-2018 UA74_07505 9a7db41a6b3148cb2d3b8276188fa8a8 580 SUPERFAMILY SSF51445 41 488 1.56E-131 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07505 9a7db41a6b3148cb2d3b8276188fa8a8 580 Gene3D G3DSA:3.90.400.10 128 197 6.0E-226 T 12-10-2018 UA74_07505 9a7db41a6b3148cb2d3b8276188fa8a8 580 SMART SM00642 38 440 3.2E-114 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_23010 414a4b85bc9941826e82cff99a6a88bc 372 Gene3D G3DSA:3.20.20.70 19 290 4.1E-35 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_23010 414a4b85bc9941826e82cff99a6a88bc 372 Pfam PF13353 4Fe-4S single cluster domain 34 134 7.9E-11 T 12-10-2018 UA74_23010 414a4b85bc9941826e82cff99a6a88bc 372 Pfam PF04055 Radical SAM superfamily 34 165 7.2E-19 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_23010 414a4b85bc9941826e82cff99a6a88bc 372 SUPERFAMILY SSF102114 25 334 3.66E-44 T 12-10-2018 UA74_04840 8830f94d8fb57537a7523fdc04aa0afa 123 Pfam PF02467 Transcription factor WhiB 41 90 1.2E-15 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain UA74_04840 8830f94d8fb57537a7523fdc04aa0afa 123 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 26 104 16.03 T 12-10-2018 IPR003482 Transcription factor WhiB UA74_04840 8830f94d8fb57537a7523fdc04aa0afa 123 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 100 110 - T 12-10-2018 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 UA74_21170 988804842d49a455dafdf69d89d9b193 274 SUPERFAMILY SSF51430 7 268 4.71E-95 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_21170 988804842d49a455dafdf69d89d9b193 274 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_21170 988804842d49a455dafdf69d89d9b193 274 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_21170 988804842d49a455dafdf69d89d9b193 274 PIRSF PIRSF000097 1 272 4.6E-88 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_21170 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.4E-49 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_21170 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 196 220 4.4E-49 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_21170 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 159 188 4.4E-49 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_21170 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 93 111 4.4E-49 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_21170 988804842d49a455dafdf69d89d9b193 274 PRINTS PR00069 Aldo-keto reductase signature 125 142 4.4E-49 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_21170 988804842d49a455dafdf69d89d9b193 274 Pfam PF00248 Aldo/keto reductase family 24 260 6.6E-48 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_21170 988804842d49a455dafdf69d89d9b193 274 Gene3D G3DSA:3.20.20.100 1 274 7.9E-117 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_21170 988804842d49a455dafdf69d89d9b193 274 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 Pfam PF07702 UTRA domain 103 243 1.5E-45 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 SUPERFAMILY SSF46785 18 93 8.88E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 2.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 2.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 SUPERFAMILY SSF64288 71 249 3.61E-55 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 SMART SM00866 103 243 2.6E-46 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 Gene3D G3DSA:3.40.1410.10 86 251 1.4E-61 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 82 1.1E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 Gene3D G3DSA:1.10.10.10 21 85 2.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_01970 b2beb42205335e4659d25bf357b8ef2d 258 SMART SM00345 26 83 1.7E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_14510 2743ce351ca4fb39472eec53bae1adbd 354 Gene3D G3DSA:3.90.180.10 30 340 1.1E-81 T 12-10-2018 UA74_14510 2743ce351ca4fb39472eec53bae1adbd 354 SUPERFAMILY SSF51735 150 310 1.21E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14510 2743ce351ca4fb39472eec53bae1adbd 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 144 1.1E-24 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_14510 2743ce351ca4fb39472eec53bae1adbd 354 SUPERFAMILY SSF50129 11 184 5.02E-38 T 12-10-2018 IPR011032 GroES-like superfamily UA74_14510 2743ce351ca4fb39472eec53bae1adbd 354 Gene3D G3DSA:3.40.50.720 163 296 1.1E-81 T 12-10-2018 UA74_14510 2743ce351ca4fb39472eec53bae1adbd 354 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_14510 2743ce351ca4fb39472eec53bae1adbd 354 Pfam PF00107 Zinc-binding dehydrogenase 185 312 5.3E-22 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_14510 2743ce351ca4fb39472eec53bae1adbd 354 SMART SM00829 19 328 2.0E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 22 539 40.31 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 Gene3D G3DSA:3.40.140.20 411 539 7.0E-49 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 SMART SM00798 153 474 4.2E-165 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 23 539 2.2E-161 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 PIRSF PIRSF000414 17 539 2.5E-187 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 SUPERFAMILY SSF52335 22 210 4.19E-62 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 Gene3D G3DSA:3.40.50.1380 14 216 2.4E-82 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 SMART SM00851 34 148 1.2E-46 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 Gene3D G3DSA:3.40.140.20 228 387 4.6E-55 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 Pfam PF01808 AICARFT/IMPCHase bienzyme 153 473 1.8E-108 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 SUPERFAMILY SSF53927 231 539 2.61E-110 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UA74_27655 fe49006ca4c46c3d10c350fc95d9ffcf 539 Pfam PF02142 MGS-like domain 34 147 1.2E-24 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain UA74_29220 f840818ec8c1a3fd5af3dc83dcfeddec 535 PIRSF PIRSF000485 37 502 5.4E-156 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 UA74_29220 f840818ec8c1a3fd5af3dc83dcfeddec 535 SUPERFAMILY SSF56235 41 301 9.44E-62 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_29220 f840818ec8c1a3fd5af3dc83dcfeddec 535 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 40 489 45.574 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 UA74_29220 f840818ec8c1a3fd5af3dc83dcfeddec 535 Pfam PF13522 Glutamine amidotransferase domain 98 243 2.4E-11 T 12-10-2018 UA74_29220 f840818ec8c1a3fd5af3dc83dcfeddec 535 Gene3D G3DSA:3.40.50.2020 308 472 2.7E-143 T 12-10-2018 UA74_29220 f840818ec8c1a3fd5af3dc83dcfeddec 535 Pfam PF00156 Phosphoribosyl transferase domain 312 419 1.0E-6 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_29220 f840818ec8c1a3fd5af3dc83dcfeddec 535 Gene3D G3DSA:3.60.20.10 41 491 2.7E-143 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_29220 f840818ec8c1a3fd5af3dc83dcfeddec 535 SUPERFAMILY SSF53271 284 498 6.69E-68 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_29220 f840818ec8c1a3fd5af3dc83dcfeddec 535 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 41 490 1.0E-154 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 UA74_06855 b5fe30b32c1ca772c495659fc7a293c1 321 Gene3D G3DSA:3.40.50.720 1 180 6.4E-15 T 12-10-2018 UA74_06855 b5fe30b32c1ca772c495659fc7a293c1 321 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 109 1.9E-8 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain UA74_23075 c830aec279708ea468cdddda06adbc3b 226 Gene3D G3DSA:3.30.70.1200 1 90 2.4E-23 T 12-10-2018 UA74_23075 c830aec279708ea468cdddda06adbc3b 226 SUPERFAMILY SSF117987 95 221 4.45E-24 T 12-10-2018 UA74_23075 c830aec279708ea468cdddda06adbc3b 226 Gene3D G3DSA:3.30.70.1210 94 221 4.4E-27 T 12-10-2018 UA74_23075 c830aec279708ea468cdddda06adbc3b 226 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 2 221 2.5E-20 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 UA74_23075 c830aec279708ea468cdddda06adbc3b 226 Pfam PF08798 CRISPR associated protein 2 221 1.3E-52 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 UA74_23075 c830aec279708ea468cdddda06adbc3b 226 SMART SM01101 1 221 4.6E-57 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 UA74_23075 c830aec279708ea468cdddda06adbc3b 226 SUPERFAMILY SSF117987 1 80 8.63E-19 T 12-10-2018 UA74_29455 0e605ba1be124ac7aa865261bcb2e10c 163 Pfam PF11349 Protein of unknown function (DUF3151) 34 157 2.6E-58 T 12-10-2018 IPR014487 Protein of unknown function DUF3151 UA74_29455 0e605ba1be124ac7aa865261bcb2e10c 163 PIRSF PIRSF017349 26 162 1.4E-59 T 12-10-2018 IPR014487 Protein of unknown function DUF3151 UA74_21625 049d1b8abb7e931f02ab608fdf2ba10d 306 PRINTS PR00474 Glutamate 5-kinase family signature 68 82 1.1E-8 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UA74_21625 049d1b8abb7e931f02ab608fdf2ba10d 306 PRINTS PR00474 Glutamate 5-kinase family signature 200 227 1.1E-8 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UA74_21625 049d1b8abb7e931f02ab608fdf2ba10d 306 PRINTS PR00474 Glutamate 5-kinase family signature 251 271 1.1E-8 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UA74_21625 049d1b8abb7e931f02ab608fdf2ba10d 306 SUPERFAMILY SSF53633 19 302 6.55E-86 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UA74_21625 049d1b8abb7e931f02ab608fdf2ba10d 306 TIGRFAM TIGR00761 argB: acetylglutamate kinase 38 276 2.3E-76 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_21625 049d1b8abb7e931f02ab608fdf2ba10d 306 Hamap MF_00082 Acetylglutamate kinase [argB]. 36 294 45.971 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_21625 049d1b8abb7e931f02ab608fdf2ba10d 306 Pfam PF00696 Amino acid kinase family 38 278 1.3E-44 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UA74_21625 049d1b8abb7e931f02ab608fdf2ba10d 306 PIRSF PIRSF000728 22 300 6.0E-99 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_21625 049d1b8abb7e931f02ab608fdf2ba10d 306 Gene3D G3DSA:3.40.1160.10 15 305 1.3E-100 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UA74_17415 c1a826af364bed8c724f1705d53510b1 490 Pfam PF07690 Major Facilitator Superfamily 26 420 4.5E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_17415 c1a826af364bed8c724f1705d53510b1 490 Gene3D G3DSA:1.20.1720.10 22 225 4.6E-37 T 12-10-2018 UA74_17415 c1a826af364bed8c724f1705d53510b1 490 Gene3D G3DSA:1.20.1250.20 264 477 7.1E-20 T 12-10-2018 UA74_17415 c1a826af364bed8c724f1705d53510b1 490 SUPERFAMILY SSF103473 20 473 5.49E-59 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SMART SM01142 836 1012 8.1E-64 T 12-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SMART SM00487 36 218 2.7E-28 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Pfam PF00270 DEAD/DEAH box helicase 42 189 2.3E-17 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Gene3D G3DSA:3.40.50.300 214 473 5.1E-56 T 12-10-2018 UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Pfam PF08148 DSHCT (NUC185) domain 839 1007 1.1E-37 T 12-10-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Pfam PF00271 Helicase conserved C-terminal domain 363 442 1.5E-4 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Gene3D G3DSA:1.10.3380.30 832 992 1.4E-13 T 12-10-2018 UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 Gene3D G3DSA:3.40.50.300 9 213 3.8E-61 T 12-10-2018 UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SUPERFAMILY SSF52540 55 456 1.93E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12935 69f1a01b5fa9b6b32f031e064e09cdc9 1012 SMART SM00490 352 442 1.3E-13 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_21560 898734bf44c0b16288369d549f4d9101 356 Gene3D G3DSA:3.40.50.1000 22 254 8.9E-72 T 12-10-2018 IPR023214 HAD superfamily UA74_21560 898734bf44c0b16288369d549f4d9101 356 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 25 251 1.8E-31 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_21560 898734bf44c0b16288369d549f4d9101 356 SUPERFAMILY SSF56784 20 276 1.76E-52 T 12-10-2018 IPR036412 HAD-like superfamily UA74_21560 898734bf44c0b16288369d549f4d9101 356 Pfam PF13344 Haloacid dehalogenase-like hydrolase 24 124 6.1E-19 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_21560 898734bf44c0b16288369d549f4d9101 356 PIRSF PIRSF000915 4 283 4.4E-57 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA UA74_21560 898734bf44c0b16288369d549f4d9101 356 Gene3D G3DSA:3.40.50.1000 89 204 8.9E-72 T 12-10-2018 IPR023214 HAD superfamily UA74_21560 898734bf44c0b16288369d549f4d9101 356 Pfam PF13242 HAD-hyrolase-like 204 275 4.7E-15 T 12-10-2018 UA74_02225 b151aacefb6d7963883cc62de4626310 172 Pfam PF10722 Putative bacterial sensory transduction regulator 14 134 6.9E-19 T 12-10-2018 IPR019660 Putative sensory transduction regulator YbjN UA74_02225 b151aacefb6d7963883cc62de4626310 172 SUPERFAMILY SSF69635 8 137 1.85E-29 T 12-10-2018 UA74_02225 b151aacefb6d7963883cc62de4626310 172 Gene3D G3DSA:3.30.1460.10 29 142 8.1E-7 T 12-10-2018 UA74_03825 1d41dabf2b82dd3f4a50dfcd2b5f26d5 273 SUPERFAMILY SSF63817 123 268 2.47E-9 T 12-10-2018 IPR023365 Sortase domain superfamily UA74_03825 1d41dabf2b82dd3f4a50dfcd2b5f26d5 273 Gene3D G3DSA:2.40.260.10 143 272 3.4E-12 T 12-10-2018 IPR023365 Sortase domain superfamily UA74_03825 1d41dabf2b82dd3f4a50dfcd2b5f26d5 273 Pfam PF04203 Sortase family 173 269 3.3E-8 T 12-10-2018 IPR005754 Sortase family UA74_21550 545a44b486949fd9a4e5642c7851387d 295 Pfam PF01479 S4 domain 5 48 4.3E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_21550 545a44b486949fd9a4e5642c7851387d 295 Pfam PF01728 FtsJ-like methyltransferase 64 247 1.9E-17 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 UA74_21550 545a44b486949fd9a4e5642c7851387d 295 SUPERFAMILY SSF53335 62 248 1.58E-19 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_21550 545a44b486949fd9a4e5642c7851387d 295 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 242 4.1E-57 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 UA74_21550 545a44b486949fd9a4e5642c7851387d 295 Gene3D G3DSA:3.10.290.10 1 64 3.8E-14 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UA74_21550 545a44b486949fd9a4e5642c7851387d 295 Gene3D G3DSA:3.40.50.150 66 277 5.6E-67 T 12-10-2018 UA74_21550 545a44b486949fd9a4e5642c7851387d 295 SMART SM00363 5 72 3.8E-5 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_21550 545a44b486949fd9a4e5642c7851387d 295 SUPERFAMILY SSF55174 4 67 1.77E-11 T 12-10-2018 UA74_21550 545a44b486949fd9a4e5642c7851387d 295 PIRSF PIRSF005578 1 270 1.4E-90 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 UA74_19000 8653039bbb9e2958188bc0425c84f70d 311 PIRSF PIRSF028754 7 311 5.5E-91 T 12-10-2018 IPR008492 Protein of unknown function DUF774 UA74_19000 8653039bbb9e2958188bc0425c84f70d 311 Gene3D G3DSA:1.10.287.100 232 272 2.2E-13 T 12-10-2018 UA74_19000 8653039bbb9e2958188bc0425c84f70d 311 Gene3D G3DSA:3.40.50.10900 2 229 7.3E-72 T 12-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily UA74_19000 8653039bbb9e2958188bc0425c84f70d 311 Pfam PF09754 PAC2 family 27 248 1.4E-44 T 12-10-2018 IPR019151 Proteasome assembly chaperone 2 UA74_19000 8653039bbb9e2958188bc0425c84f70d 311 SUPERFAMILY SSF159659 5 271 1.44E-82 T 12-10-2018 UA74_23890 28fe16dc4874a477987f2e301a3dab77 286 SMART SM00342 195 279 3.5E-11 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_23890 28fe16dc4874a477987f2e301a3dab77 286 SUPERFAMILY SSF46689 247 282 4.93E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_23890 28fe16dc4874a477987f2e301a3dab77 286 Gene3D G3DSA:1.10.10.60 180 284 2.9E-19 T 12-10-2018 UA74_23890 28fe16dc4874a477987f2e301a3dab77 286 Pfam PF12833 Helix-turn-helix domain 201 280 8.4E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 114 1.3E-44 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.537 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 SUPERFAMILY SSF74731 3 117 4.58E-46 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.3E-38 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.3E-38 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.3E-38 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 Gene3D G3DSA:1.10.1900.20 56 119 5.2E-27 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 2.0E-21 T 12-10-2018 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 Gene3D G3DSA:1.10.720.90 2 55 1.7E-19 T 12-10-2018 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 Pfam PF00453 Ribosomal protein L20 3 108 7.6E-45 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21690 b8f114ce4dc36f034db45dc9e9116fa5 126 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 SUPERFAMILY SSF52540 10 580 7.48E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:1.10.8.280 292 409 6.6E-264 T 12-10-2018 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:3.40.50.300 6 606 6.6E-264 T 12-10-2018 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:3.40.50.300 627 946 1.2E-143 T 12-10-2018 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:1.20.1580.10 702 840 1.2E-143 T 12-10-2018 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:1.20.1580.10 91 503 6.6E-264 T 12-10-2018 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 950 22.794 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 SUPERFAMILY SSF52540 625 924 6.12E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 Gene3D G3DSA:3.30.190.20 131 248 6.6E-264 T 12-10-2018 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 ProSitePatterns PS00211 ABC transporters family signature. 840 854 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 Pfam PF00005 ABC transporter 634 870 3.8E-9 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_21715 f61e7fba1d43a20365521fa24b1a6562 950 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 934 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 UA74_12980 c1e1187234b574c987c5193b0f01c84b 298 SUPERFAMILY SSF53335 31 248 6.91E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_12980 c1e1187234b574c987c5193b0f01c84b 298 Gene3D G3DSA:3.40.50.150 28 295 7.5E-64 T 12-10-2018 UA74_12980 c1e1187234b574c987c5193b0f01c84b 298 Pfam PF13649 Methyltransferase domain 112 196 5.8E-7 T 12-10-2018 UA74_12980 c1e1187234b574c987c5193b0f01c84b 298 PIRSF PIRSF018249 17 298 3.5E-84 T 12-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 SMART SM00304 166 218 5.8E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 5.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 411 5.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 SUPERFAMILY SSF55874 284 429 6.36E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 SMART SM00387 325 433 4.7E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 SUPERFAMILY SSF47384 205 268 1.02E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 273 4.1E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 Gene3D G3DSA:1.10.287.130 164 270 3.3E-19 T 12-10-2018 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 SUPERFAMILY SSF158472 167 216 7.72E-5 T 12-10-2018 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 SMART SM00388 219 277 1.3E-4 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 Pfam PF00672 HAMP domain 166 214 7.6E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_08770 3c79c5784a5b6b345d0df82f838c9749 434 Gene3D G3DSA:3.30.565.10 290 430 4.0E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 TIGRFAM TIGR00191 thrB: homoserine kinase 4 263 2.4E-59 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 Gene3D G3DSA:3.30.230.10 6 160 8.8E-75 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 87 98 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 245 260 4.0E-30 T 12-10-2018 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 11 26 4.0E-30 T 12-10-2018 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 168 185 4.0E-30 T 12-10-2018 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 94 109 4.0E-30 T 12-10-2018 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 PRINTS PR00958 Homoserine kinase signature 127 140 4.0E-30 T 12-10-2018 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 Hamap MF_00384 Homoserine kinase [thrB]. 6 290 27.564 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 Pfam PF00288 GHMP kinases N terminal domain 81 140 6.6E-12 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 Gene3D G3DSA:3.30.70.890 161 261 8.8E-75 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 SUPERFAMILY SSF54211 4 149 5.31E-30 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 PIRSF PIRSF000676 1 276 7.4E-71 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 UA74_06980 00de285d6bd8cb73f3e843d5d5a4328c 292 SUPERFAMILY SSF55060 165 267 2.09E-20 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 27 233 6.0E-68 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 Hamap MF_00104 Ribonuclease 3 [rnc]. 16 232 29.199 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 Pfam PF14622 Ribonuclease-III-like 27 152 1.3E-35 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 ProSitePatterns PS00517 Ribonuclease III family signature. 49 57 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 SMART SM00358 170 236 4.6E-22 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 Gene3D G3DSA:1.10.1520.10 9 162 6.9E-45 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 SUPERFAMILY SSF54768 124 235 1.57E-24 T 12-10-2018 UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 SUPERFAMILY SSF69065 12 170 6.98E-43 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 SMART SM00535 27 163 1.8E-50 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 Pfam PF00035 Double-stranded RNA binding motif 170 235 5.2E-15 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain UA74_25590 8934ee3d9bfc4f7dbaa271a8d281c07f 296 Gene3D G3DSA:3.30.160.20 169 234 1.4E-19 T 12-10-2018 UA74_00685 8fa2c1fb352c2bc0958a393c3c6c7b91 672 Gene3D G3DSA:3.90.550.60 53 445 2.6E-135 T 12-10-2018 UA74_00685 8fa2c1fb352c2bc0958a393c3c6c7b91 672 SUPERFAMILY SSF53448 240 464 2.81E-22 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_00685 8fa2c1fb352c2bc0958a393c3c6c7b91 672 Pfam PF13641 Glycosyltransferase like family 2 208 461 3.9E-36 T 12-10-2018 UA74_13775 1871614a56c73ef8920f32e40320a04e 222 Gene3D G3DSA:3.30.70.2660 10 218 1.5E-74 T 12-10-2018 UA74_13775 1871614a56c73ef8920f32e40320a04e 222 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 17 56 2.2E-14 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_13775 1871614a56c73ef8920f32e40320a04e 222 TIGRFAM TIGR01876 cas_Cas5d: CRISPR-associated protein Cas5, subtype I-C/DVULG 17 211 3.1E-41 T 12-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 UA74_13775 1871614a56c73ef8920f32e40320a04e 222 PIRSF PIRSF029950 9 218 2.2E-61 T 12-10-2018 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d GO:0004519|GO:0051607 UA74_13775 1871614a56c73ef8920f32e40320a04e 222 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 17 208 1.3E-29 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_12465 a64ec48993a831e5390e1ec530175b2e 203 Gene3D G3DSA:3.10.50.40 82 199 2.0E-24 T 12-10-2018 UA74_12465 a64ec48993a831e5390e1ec530175b2e 203 SUPERFAMILY SSF54534 75 198 5.11E-26 T 12-10-2018 UA74_12465 a64ec48993a831e5390e1ec530175b2e 203 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 108 197 1.8E-17 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 183 199 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1436 1451 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SMART SM00823 Phosphopantetheine attachment site 1409 1481 6.0E-30 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:1.10.1200.10 1392 1485 5.4E-32 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF08659 KR domain 1125 1303 1.5E-59 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF51735 1121 1354 3.8E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 278 395 3.4E-44 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.40.366.10 553 848 4.0E-159 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF53901 33 388 4.88E-96 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 555 845 1.2E-112 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 398 519 7.6E-15 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF51735 898 1112 1.23E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF52151 552 835 3.14E-67 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF55048 681 743 1.44E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1125 1305 8.8E-48 T 12-10-2018 UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SMART SM01294 1410 1477 4.2E-4 T 12-10-2018 UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 270 2.7E-76 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.40.47.10 18 449 5.7E-176 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF00550 Phosphopantetheine attachment site 1412 1477 2.7E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SUPERFAMILY SSF47336 1403 1488 5.89E-20 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 SMART SM00825 Beta-ketoacyl synthase 37 448 9.4E-199 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Pfam PF00698 Acyl transferase domain 554 847 7.6E-54 T 12-10-2018 IPR014043 Acyl transferase UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.30.70.3290 469 887 4.0E-159 T 12-10-2018 UA74_16445 2385cf8de4683c49a56c106529a9f502 1570 Gene3D G3DSA:3.40.50.720 888 1378 3.1E-141 T 12-10-2018 UA74_01265 8a67ef00caadf0c3b4099e40b885adcc 198 SUPERFAMILY SSF52833 66 194 7.19E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_01265 8a67ef00caadf0c3b4099e40b885adcc 198 Gene3D G3DSA:3.40.30.10 60 197 6.4E-19 T 12-10-2018 UA74_01265 8a67ef00caadf0c3b4099e40b885adcc 198 ProSitePatterns PS00194 Thioredoxin family active site. 88 106 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_01265 8a67ef00caadf0c3b4099e40b885adcc 198 Pfam PF00578 AhpC/TSA family 71 172 4.5E-9 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_14205 bdae360972f99a2c094d88db3d4ce5d6 218 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 187 7.6E-41 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal UA74_14205 bdae360972f99a2c094d88db3d4ce5d6 218 SUPERFAMILY SSF53639 4 213 2.94E-50 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UA74_14205 bdae360972f99a2c094d88db3d4ce5d6 218 Gene3D G3DSA:3.40.225.10 2 213 2.1E-52 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UA74_14205 bdae360972f99a2c094d88db3d4ce5d6 218 SMART SM01007 6 188 1.4E-48 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 SUPERFAMILY SSF88659 114 184 3.36E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 SUPERFAMILY SSF88659 175 253 4.86E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 250 2.4E-32 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 PRINTS PR00046 Major sigma-70 factor signature 223 238 1.5E-6 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 PRINTS PR00046 Major sigma-70 factor signature 206 218 1.5E-6 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 PRINTS PR00046 Major sigma-70 factor signature 65 78 1.5E-6 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 Pfam PF04542 Sigma-70 region 2 41 110 2.6E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 Pfam PF04545 Sigma-70, region 4 202 251 1.4E-14 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 Pfam PF04539 Sigma-70 region 3 125 163 4.3E-9 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 35 251 5.1E-79 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 Gene3D G3DSA:1.10.10.10 111 163 1.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 SUPERFAMILY SSF88946 14 110 4.45E-28 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 Gene3D G3DSA:1.10.10.10 175 255 8.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23430 2ad3176642a752dccdfa0b91f8c1e670 261 Gene3D G3DSA:1.20.120.1810 2 109 5.3E-18 T 12-10-2018 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 30 161 5.0E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 PRINTS PR00315 GTP-binding elongation factor signature 28 41 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 PRINTS PR00315 GTP-binding elongation factor signature 78 86 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 PRINTS PR00315 GTP-binding elongation factor signature 98 108 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 PRINTS PR00315 GTP-binding elongation factor signature 150 159 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 PRINTS PR00315 GTP-binding elongation factor signature 114 125 3.1E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 SUPERFAMILY SSF54980 404 477 2.09E-10 T 12-10-2018 IPR035647 EF-G domain III/V-like UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 Gene3D G3DSA:3.40.50.300 27 389 1.4E-93 T 12-10-2018 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 Gene3D G3DSA:3.30.70.3280 401 538 2.5E-37 T 12-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 17 537 47.201 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 SUPERFAMILY SSF52540 23 287 8.54E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 21 535 7.1E-156 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 SUPERFAMILY SSF50447 272 399 1.06E-23 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 71 86 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 Pfam PF00009 Elongation factor Tu GTP binding domain 26 287 1.8E-48 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 Pfam PF16658 Class II release factor RF3, C-terminal domain 398 523 7.1E-36 T 12-10-2018 IPR032090 Peptide chain release factor 3, C-terminal UA74_11165 e9e2a8cfea29774f37e33d53158154a2 540 Gene3D G3DSA:3.40.50.300 34 285 1.4E-93 T 12-10-2018 UA74_22205 4645eaea18c15f6610d08d4742aed901 194 SMART SM00530 15 70 1.2E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_22205 4645eaea18c15f6610d08d4742aed901 194 Gene3D G3DSA:1.10.260.40 7 77 6.5E-15 T 12-10-2018 UA74_22205 4645eaea18c15f6610d08d4742aed901 194 Pfam PF13560 Helix-turn-helix domain 11 69 1.2E-12 T 12-10-2018 UA74_22205 4645eaea18c15f6610d08d4742aed901 194 Gene3D G3DSA:2.60.120.10 88 191 3.1E-13 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_22205 4645eaea18c15f6610d08d4742aed901 194 Pfam PF07883 Cupin domain 116 177 8.8E-15 T 12-10-2018 IPR013096 Cupin 2, conserved barrel UA74_22205 4645eaea18c15f6610d08d4742aed901 194 SUPERFAMILY SSF51182 67 177 9.24E-23 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_22205 4645eaea18c15f6610d08d4742aed901 194 SUPERFAMILY SSF47413 7 77 3.66E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_18860 61a4688226c2ad5fb3bd6aae4cb742e3 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 283 1.0E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_18860 61a4688226c2ad5fb3bd6aae4cb742e3 296 SUPERFAMILY SSF161098 31 291 1.44E-54 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18860 61a4688226c2ad5fb3bd6aae4cb742e3 296 Gene3D G3DSA:1.10.3720.10 30 284 2.3E-51 T 12-10-2018 IPR035906 MetI-like superfamily UA74_03580 61f5ded7214b285f4405797d8710c5d1 452 Pfam PF07690 Major Facilitator Superfamily 67 401 3.1E-14 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_03580 61f5ded7214b285f4405797d8710c5d1 452 Gene3D G3DSA:1.20.1250.20 54 243 5.0E-10 T 12-10-2018 UA74_03580 61f5ded7214b285f4405797d8710c5d1 452 Gene3D G3DSA:1.20.1250.20 261 444 1.2E-6 T 12-10-2018 UA74_03580 61f5ded7214b285f4405797d8710c5d1 452 SUPERFAMILY SSF103473 61 447 7.32E-24 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_18655 0295a7963e793d539ccd2cf66b55859b 265 SUPERFAMILY SSF56235 39 259 7.12E-53 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_18655 0295a7963e793d539ccd2cf66b55859b 265 Pfam PF00227 Proteasome subunit 49 229 5.5E-37 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 UA74_18655 0295a7963e793d539ccd2cf66b55859b 265 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 49 260 4.8E-93 T 12-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UA74_18655 0295a7963e793d539ccd2cf66b55859b 265 PRINTS PR00141 Proteasome component signature 186 197 2.2E-5 T 12-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 UA74_18655 0295a7963e793d539ccd2cf66b55859b 265 PRINTS PR00141 Proteasome component signature 197 208 2.2E-5 T 12-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 UA74_18655 0295a7963e793d539ccd2cf66b55859b 265 PRINTS PR00141 Proteasome component signature 59 74 2.2E-5 T 12-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 UA74_18655 0295a7963e793d539ccd2cf66b55859b 265 Gene3D G3DSA:3.60.20.10 52 264 5.6E-75 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_15445 fcc2ad63299cd8a0713b157dade04d52 251 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 137 147 - T 12-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 UA74_15445 fcc2ad63299cd8a0713b157dade04d52 251 Pfam PF13350 Tyrosine phosphatase family 6 242 3.9E-59 T 12-10-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type UA74_15445 fcc2ad63299cd8a0713b157dade04d52 251 Gene3D G3DSA:3.90.190.10 6 241 1.1E-55 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like UA74_15445 fcc2ad63299cd8a0713b157dade04d52 251 SUPERFAMILY SSF52799 5 239 1.09E-44 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like UA74_25195 5e1440d294ba11c536c7e72d5627f7e4 634 Gene3D G3DSA:3.30.2010.10 407 494 3.7E-5 T 12-10-2018 UA74_25195 5e1440d294ba11c536c7e72d5627f7e4 634 Pfam PF01435 Peptidase family M48 424 626 8.8E-21 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 UA74_02855 76238fdef7e4a98a65fd2e7cb28ce522 127 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 127 23.102 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02855 76238fdef7e4a98a65fd2e7cb28ce522 127 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 102 3.0E-13 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02855 76238fdef7e4a98a65fd2e7cb28ce522 127 Gene3D G3DSA:3.30.1390.10 57 127 1.5E-27 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UA74_02855 76238fdef7e4a98a65fd2e7cb28ce522 127 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 127 1.4E-46 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02855 76238fdef7e4a98a65fd2e7cb28ce522 127 SUPERFAMILY SSF48300 5 62 8.89E-13 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02855 76238fdef7e4a98a65fd2e7cb28ce522 127 Gene3D G3DSA:1.20.5.710 4 56 3.1E-15 T 12-10-2018 UA74_02855 76238fdef7e4a98a65fd2e7cb28ce522 127 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 127 5.9E-26 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02855 76238fdef7e4a98a65fd2e7cb28ce522 127 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 7 53 1.2E-15 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02855 76238fdef7e4a98a65fd2e7cb28ce522 127 SUPERFAMILY SSF54736 55 127 1.12E-20 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UA74_00410 3489b1da902e483cd527cc8c17b1aeb2 171 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 6 160 1.4E-44 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_00410 3489b1da902e483cd527cc8c17b1aeb2 171 Gene3D G3DSA:1.10.1740.10 3 81 6.0E-8 T 12-10-2018 UA74_00410 3489b1da902e483cd527cc8c17b1aeb2 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 158 1.5E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_00410 3489b1da902e483cd527cc8c17b1aeb2 171 Gene3D G3DSA:1.10.10.10 86 162 8.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_00410 3489b1da902e483cd527cc8c17b1aeb2 171 SUPERFAMILY SSF88946 4 89 1.41E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_00410 3489b1da902e483cd527cc8c17b1aeb2 171 Pfam PF08281 Sigma-70, region 4 102 155 1.6E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_00410 3489b1da902e483cd527cc8c17b1aeb2 171 SUPERFAMILY SSF88659 100 159 2.43E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_00410 3489b1da902e483cd527cc8c17b1aeb2 171 Pfam PF04542 Sigma-70 region 2 22 79 1.1E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_16960 a96bd105f6b366744619906ae3665677 329 SUPERFAMILY SSF75005 76 263 4.71E-17 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_16960 a96bd105f6b366744619906ae3665677 329 Gene3D G3DSA:2.115.10.20 206 328 2.2E-5 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_16960 a96bd105f6b366744619906ae3665677 329 Gene3D G3DSA:2.115.10.20 73 205 7.0E-17 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_16960 a96bd105f6b366744619906ae3665677 329 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 31 6.8E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 PIRSF PIRSF004803 15 563 6.9E-194 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 Gene3D G3DSA:3.60.15.10 21 447 7.4E-168 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 Pfam PF12706 Beta-lactamase superfamily domain 61 179 1.8E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 SMART SM00849 32 226 1.2E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 Gene3D G3DSA:3.10.20.580 460 563 4.2E-15 T 12-10-2018 UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 SUPERFAMILY SSF56281 20 435 4.32E-93 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 Gene3D G3DSA:3.40.50.10710 218 376 7.4E-168 T 12-10-2018 UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 Hamap MF_01491 Ribonuclease J [rnj]. 15 563 40.335 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 372 419 2.7E-10 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 21 560 9.4E-146 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 UA74_09495 6fcff1d9f35511d6f7268099060c9782 563 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 375 403 - T 12-10-2018 IPR001587 Ribonuclease J, conserved site UA74_07325 7390047dc088ce749701bdd745184dce 336 Pfam PF13377 Periplasmic binding protein-like domain 168 330 2.8E-27 T 12-10-2018 UA74_07325 7390047dc088ce749701bdd745184dce 336 SUPERFAMILY SSF53822 58 324 8.78E-37 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_07325 7390047dc088ce749701bdd745184dce 336 Gene3D G3DSA:3.40.50.2300 56 307 9.8E-42 T 12-10-2018 UA74_07325 7390047dc088ce749701bdd745184dce 336 SMART SM00354 1 71 6.1E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_07325 7390047dc088ce749701bdd745184dce 336 Gene3D G3DSA:3.40.50.2300 160 291 9.8E-42 T 12-10-2018 UA74_07325 7390047dc088ce749701bdd745184dce 336 SUPERFAMILY SSF47413 2 60 2.35E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_07325 7390047dc088ce749701bdd745184dce 336 Gene3D G3DSA:1.10.260.40 1 55 9.9E-20 T 12-10-2018 UA74_07325 7390047dc088ce749701bdd745184dce 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 1.8E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_27400 c03c022345cb4c0731df2049d512feac 477 Gene3D G3DSA:3.40.605.10 26 476 9.3E-174 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_27400 c03c022345cb4c0731df2049d512feac 477 Gene3D G3DSA:3.40.309.10 261 450 9.3E-174 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_27400 c03c022345cb4c0731df2049d512feac 477 SUPERFAMILY SSF53720 16 476 1.19E-160 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_27400 c03c022345cb4c0731df2049d512feac 477 Pfam PF00171 Aldehyde dehydrogenase family 30 476 1.3E-162 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_27400 c03c022345cb4c0731df2049d512feac 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UA74_23370 513f9794adad5d60c05f4e4fe4fe22ec 189 SUPERFAMILY SSF53597 3 186 4.19E-19 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_23370 513f9794adad5d60c05f4e4fe4fe22ec 189 Pfam PF01872 RibD C-terminal domain 4 179 1.5E-13 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_23370 513f9794adad5d60c05f4e4fe4fe22ec 189 Gene3D G3DSA:3.40.430.10 3 185 1.4E-29 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_24305 ba82601cc71197631cd3b5d0c28a6713 273 SMART SM00530 9 81 6.4E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_24305 ba82601cc71197631cd3b5d0c28a6713 273 Gene3D G3DSA:1.10.260.40 24 80 4.3E-6 T 12-10-2018 UA74_24305 ba82601cc71197631cd3b5d0c28a6713 273 SUPERFAMILY SSF47413 29 80 8.28E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_24305 ba82601cc71197631cd3b5d0c28a6713 273 Pfam PF13560 Helix-turn-helix domain 5 82 1.5E-14 T 12-10-2018 UA74_08575 aedc9923eb2edd8f93c31ebd1c2c793d 226 SUPERFAMILY SSF161098 20 214 7.46E-36 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08575 aedc9923eb2edd8f93c31ebd1c2c793d 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 222 1.3E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_08575 aedc9923eb2edd8f93c31ebd1c2c793d 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 20 117 1.7E-19 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UA74_08575 aedc9923eb2edd8f93c31ebd1c2c793d 226 Gene3D G3DSA:1.10.3720.10 11 224 2.0E-43 T 12-10-2018 IPR035906 MetI-like superfamily UA74_29505 d38556e62d0badffaeeb2ba682864f50 466 Gene3D G3DSA:3.40.710.10 15 329 4.1E-67 T 12-10-2018 UA74_29505 d38556e62d0badffaeeb2ba682864f50 466 SUPERFAMILY SSF56601 21 341 2.05E-65 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_29505 d38556e62d0badffaeeb2ba682864f50 466 Pfam PF00144 Beta-lactamase 26 329 1.9E-52 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_23595 7a016297af8da2cc7e303b6d9ffc8651 319 Pfam PF02353 Mycolic acid cyclopropane synthetase 92 288 1.1E-38 T 12-10-2018 UA74_23595 7a016297af8da2cc7e303b6d9ffc8651 319 PIRSF PIRSF003085 89 308 5.3E-57 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 UA74_23595 7a016297af8da2cc7e303b6d9ffc8651 319 Gene3D G3DSA:3.40.50.150 90 296 2.1E-48 T 12-10-2018 UA74_23595 7a016297af8da2cc7e303b6d9ffc8651 319 SUPERFAMILY SSF53335 92 293 4.54E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_19855 16bc937f7cafcfc3d3553de47aaf5646 321 Pfam PF01636 Phosphotransferase enzyme family 26 173 3.3E-17 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_19855 16bc937f7cafcfc3d3553de47aaf5646 321 SUPERFAMILY SSF56112 20 171 1.64E-20 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_19855 16bc937f7cafcfc3d3553de47aaf5646 321 Gene3D G3DSA:3.90.1200.10 36 168 2.1E-5 T 12-10-2018 UA74_04105 5f9a5bab1a238e205bb3837356125c20 488 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 87 2.2E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_04105 5f9a5bab1a238e205bb3837356125c20 488 Gene3D G3DSA:3.40.640.10 101 462 1.2E-103 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_04105 5f9a5bab1a238e205bb3837356125c20 488 Pfam PF00155 Aminotransferase class I and II 135 462 5.7E-22 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_04105 5f9a5bab1a238e205bb3837356125c20 488 SMART SM00345 28 87 1.0E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_04105 5f9a5bab1a238e205bb3837356125c20 488 Gene3D G3DSA:1.10.10.10 22 93 2.5E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04105 5f9a5bab1a238e205bb3837356125c20 488 SUPERFAMILY SSF53383 106 466 9.94E-84 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_04105 5f9a5bab1a238e205bb3837356125c20 488 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 1.2E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_04105 5f9a5bab1a238e205bb3837356125c20 488 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 1.2E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_04105 5f9a5bab1a238e205bb3837356125c20 488 SUPERFAMILY SSF46785 23 90 5.0E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_11105 2b2cca74d8d4fcad385d1b33277d7696 233 SUPERFAMILY SSF56281 6 226 5.96E-49 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_11105 2b2cca74d8d4fcad385d1b33277d7696 233 SMART SM00849 12 209 9.4E-35 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_11105 2b2cca74d8d4fcad385d1b33277d7696 233 Pfam PF00753 Metallo-beta-lactamase superfamily 9 209 4.5E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_11105 2b2cca74d8d4fcad385d1b33277d7696 233 Gene3D G3DSA:3.60.15.10 2 229 1.4E-60 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF53901 3 411 1.81E-58 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 586 882 2.1E-38 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 290 8.3E-52 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SMART SM00825 Beta-ketoacyl synthase 6 466 1.4E-60 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 298 411 6.0E-32 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 424 540 6.3E-8 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1234 1417 2.2E-17 T 12-10-2018 UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF47336 949 1028 7.81E-5 T 12-10-2018 IPR036736 ACP-like superfamily UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF54637 1481 1558 9.51E-7 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.40.47.10 1 469 5.4E-124 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SMART SM00826 1478 1640 8.5E-4 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF14765 Polyketide synthase dehydratase 1487 1759 4.8E-43 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF55048 693 756 6.28E-11 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.10.129.110 1499 1758 7.2E-29 T 12-10-2018 UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF08659 KR domain 1236 1415 2.8E-31 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:1.10.1200.10 937 1033 4.3E-11 T 12-10-2018 IPR036736 ACP-like superfamily UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF52151 582 856 3.92E-43 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.40.366.20 485 888 1.6E-88 T 12-10-2018 UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Pfam PF00698 Acyl transferase domain 620 841 1.2E-24 T 12-10-2018 IPR014043 Acyl transferase UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 SUPERFAMILY SSF51735 1234 1476 4.77E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18585 cff9ede7aef13e58ff7deab30c57668d 1997 Gene3D G3DSA:3.40.50.720 1045 1463 5.7E-67 T 12-10-2018 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 259 286 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 81 92 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 PIRSF PIRSF039102 1 318 9.1E-74 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 SUPERFAMILY SSF52440 1 113 1.25E-22 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 315 2.7E-75 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 Pfam PF01820 D-ala D-ala ligase N-terminus 4 104 8.9E-20 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 316 31.605 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 Gene3D G3DSA:3.40.50.20 18 312 3.8E-84 T 12-10-2018 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 Gene3D G3DSA:3.30.1490.20 130 190 3.8E-84 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 Pfam PF07478 D-ala D-ala ligase C-terminus 148 313 2.9E-47 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 Gene3D G3DSA:3.30.470.20 103 306 3.8E-84 T 12-10-2018 UA74_19215 302c9ae453a57058e492f7bd5450f6b8 330 SUPERFAMILY SSF56059 114 318 6.68E-45 T 12-10-2018 UA74_06160 b65773549ed50273cb9fbd71518469db 682 SUPERFAMILY SSF52540 14 645 8.1E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_06160 b65773549ed50273cb9fbd71518469db 682 SUPERFAMILY SSF52540 206 641 1.55E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_06160 b65773549ed50273cb9fbd71518469db 682 SMART SM00487 24 308 2.7E-4 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_06160 b65773549ed50273cb9fbd71518469db 682 Gene3D G3DSA:3.40.50.300 493 677 2.0E-29 T 12-10-2018 UA74_06160 b65773549ed50273cb9fbd71518469db 682 Pfam PF00270 DEAD/DEAH box helicase 37 93 9.5E-6 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_06160 b65773549ed50273cb9fbd71518469db 682 SMART SM00491 521 650 7.0E-41 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 UA74_06160 b65773549ed50273cb9fbd71518469db 682 Pfam PF13307 Helicase C-terminal domain 504 663 1.1E-27 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 UA74_06160 b65773549ed50273cb9fbd71518469db 682 Gene3D G3DSA:3.40.50.300 27 289 1.5E-45 T 12-10-2018 UA74_19050 c9b31d27a8a08de7d123acd1d74a0c66 268 SMART SM00382 35 224 9.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_19050 c9b31d27a8a08de7d123acd1d74a0c66 268 SUPERFAMILY SSF52540 6 226 6.37E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19050 c9b31d27a8a08de7d123acd1d74a0c66 268 Pfam PF00005 ABC transporter 26 167 6.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_19050 c9b31d27a8a08de7d123acd1d74a0c66 268 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_19050 c9b31d27a8a08de7d123acd1d74a0c66 268 Gene3D G3DSA:3.40.50.300 1 238 4.4E-62 T 12-10-2018 UA74_03905 60b19a0b62929c12d0d24a163ddad6f8 509 SUPERFAMILY SSF51445 28 390 8.35E-110 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_03905 60b19a0b62929c12d0d24a163ddad6f8 509 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 301 501 1.3E-42 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 UA74_03905 60b19a0b62929c12d0d24a163ddad6f8 509 SUPERFAMILY SSF51011 381 508 8.63E-35 T 12-10-2018 UA74_03905 60b19a0b62929c12d0d24a163ddad6f8 509 Gene3D G3DSA:3.20.20.80 28 391 4.1E-219 T 12-10-2018 UA74_03905 60b19a0b62929c12d0d24a163ddad6f8 509 SMART SM00813 301 501 4.0E-79 T 12-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 UA74_03905 60b19a0b62929c12d0d24a163ddad6f8 509 Gene3D G3DSA:2.60.40.1180 17 506 4.1E-219 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_27815 9147263c31c8437b40aee7a9770e1a8c 485 Pfam PF04024 PspC domain 33 84 8.3E-11 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal UA74_27815 9147263c31c8437b40aee7a9770e1a8c 485 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 392 482 1.9E-7 T 12-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF UA74_12230 a72dcf6056a4c47ffa0028cd391daf87 96 SMART SM01409 28 92 1.3E-14 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 UA74_12230 a72dcf6056a4c47ffa0028cd391daf87 96 Gene3D G3DSA:3.90.940.10 21 96 3.5E-20 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 UA74_12230 a72dcf6056a4c47ffa0028cd391daf87 96 SUPERFAMILY SSF63562 21 92 3.66E-23 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 UA74_12230 a72dcf6056a4c47ffa0028cd391daf87 96 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 21 91 1.5E-25 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_12230 a72dcf6056a4c47ffa0028cd391daf87 96 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 21 93 14.491 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_12230 a72dcf6056a4c47ffa0028cd391daf87 96 Pfam PF01192 RNA polymerase Rpb6 28 90 1.1E-15 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 UA74_28555 850eb8190912a5a8c79e9107ca1afd28 438 SMART SM00220 13 274 1.3E-48 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_28555 850eb8190912a5a8c79e9107ca1afd28 438 Gene3D G3DSA:3.30.200.20 4 91 5.4E-28 T 12-10-2018 UA74_28555 850eb8190912a5a8c79e9107ca1afd28 438 Pfam PF00069 Protein kinase domain 13 261 7.8E-39 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_28555 850eb8190912a5a8c79e9107ca1afd28 438 SUPERFAMILY SSF56112 9 314 1.16E-61 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_28555 850eb8190912a5a8c79e9107ca1afd28 438 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_28555 850eb8190912a5a8c79e9107ca1afd28 438 Gene3D G3DSA:1.10.510.10 95 280 1.1E-40 T 12-10-2018 UA74_30095 edb196c75d4313f8de1f0f6443d3eff5 285 Pfam PF00990 Diguanylate cyclase, GGDEF domain 139 236 7.6E-22 T 12-10-2018 IPR000160 GGDEF domain UA74_30095 edb196c75d4313f8de1f0f6443d3eff5 285 SMART SM00267 125 282 5.8E-7 T 12-10-2018 IPR000160 GGDEF domain UA74_30095 edb196c75d4313f8de1f0f6443d3eff5 285 SUPERFAMILY SSF55073 142 281 7.69E-23 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_30095 edb196c75d4313f8de1f0f6443d3eff5 285 Gene3D G3DSA:3.30.70.270 138 284 2.0E-25 T 12-10-2018 UA74_30095 edb196c75d4313f8de1f0f6443d3eff5 285 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 137 238 5.4E-19 T 12-10-2018 IPR000160 GGDEF domain UA74_13720 9dbef47ba92fa4045321322f12c97170 301 Gene3D G3DSA:1.10.10.10 166 301 2.4E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13720 9dbef47ba92fa4045321322f12c97170 301 SUPERFAMILY SSF46785 169 300 9.52E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 3.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 3.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 3.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 257 1.1E-59 T 12-10-2018 UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 SUPERFAMILY SSF51735 18 258 2.83E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 2.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 2.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 2.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 2.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 2.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 Gene3D G3DSA:3.40.50.720 13 259 2.7E-77 T 12-10-2018 UA74_13485 546c1e965efd24fc85cdac5ceedd7278 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 19 197 0.004 T 12-10-2018 UA74_24340 1046b14d2108d8c7a6961098c5329e6c 259 Gene3D G3DSA:1.10.150.290 132 238 1.6E-78 T 12-10-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 UA74_24340 1046b14d2108d8c7a6961098c5329e6c 259 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 4 258 40.648 T 12-10-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 UA74_24340 1046b14d2108d8c7a6961098c5329e6c 259 Gene3D G3DSA:3.40.50.150 11 255 1.6E-78 T 12-10-2018 UA74_24340 1046b14d2108d8c7a6961098c5329e6c 259 Pfam PF13489 Methyltransferase domain 17 145 4.2E-16 T 12-10-2018 UA74_24340 1046b14d2108d8c7a6961098c5329e6c 259 SUPERFAMILY SSF53335 15 257 2.32E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_12070 1296c7668e81970fab20c0d31e3d2686 281 Pfam PF13560 Helix-turn-helix domain 14 75 1.4E-8 T 12-10-2018 UA74_12070 1296c7668e81970fab20c0d31e3d2686 281 Gene3D G3DSA:1.10.260.40 9 75 1.1E-7 T 12-10-2018 UA74_12070 1296c7668e81970fab20c0d31e3d2686 281 SMART SM00530 17 72 0.0032 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_12070 1296c7668e81970fab20c0d31e3d2686 281 SUPERFAMILY SSF47413 8 72 4.1E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_26145 f9a6ecb818ae5cde35b7515f9af662c0 540 Pfam PF07690 Major Facilitator Superfamily 41 427 2.3E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_26145 f9a6ecb818ae5cde35b7515f9af662c0 540 Gene3D G3DSA:1.20.1250.20 277 446 1.1E-15 T 12-10-2018 UA74_26145 f9a6ecb818ae5cde35b7515f9af662c0 540 SUPERFAMILY SSF103473 18 515 1.03E-61 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_26145 f9a6ecb818ae5cde35b7515f9af662c0 540 Gene3D G3DSA:1.20.1720.10 33 237 1.3E-42 T 12-10-2018 UA74_03035 230dfc7ebf5e85adbd28b503cd519d3f 60 SUPERFAMILY SSF55129 1 60 1.44E-21 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily UA74_03035 230dfc7ebf5e85adbd28b503cd519d3f 60 PIRSF PIRSF002211 1 60 2.2E-28 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03035 230dfc7ebf5e85adbd28b503cd519d3f 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 7.2E-18 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain UA74_03035 230dfc7ebf5e85adbd28b503cd519d3f 60 Gene3D G3DSA:3.30.1390.20 1 60 1.2E-25 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily UA74_03035 230dfc7ebf5e85adbd28b503cd519d3f 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 2.6E-23 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03035 230dfc7ebf5e85adbd28b503cd519d3f 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.081 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03035 230dfc7ebf5e85adbd28b503cd519d3f 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 12-10-2018 IPR018038 Ribosomal protein L30, conserved site UA74_16785 7301a47fcd23b6710b901c93e2c6d96e 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 417 436 4.0E-5 T 12-10-2018 UA74_16785 7301a47fcd23b6710b901c93e2c6d96e 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 124 144 4.0E-5 T 12-10-2018 UA74_16785 7301a47fcd23b6710b901c93e2c6d96e 532 PRINTS PR01036 Tetracycline resistance protein TetB signature 179 203 4.0E-5 T 12-10-2018 UA74_16785 7301a47fcd23b6710b901c93e2c6d96e 532 Gene3D G3DSA:1.20.1250.20 285 516 2.0E-25 T 12-10-2018 UA74_16785 7301a47fcd23b6710b901c93e2c6d96e 532 Pfam PF07690 Major Facilitator Superfamily 34 426 1.0E-51 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_16785 7301a47fcd23b6710b901c93e2c6d96e 532 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 506 2.1E-70 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UA74_16785 7301a47fcd23b6710b901c93e2c6d96e 532 SUPERFAMILY SSF103473 24 515 1.31E-68 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_16785 7301a47fcd23b6710b901c93e2c6d96e 532 Gene3D G3DSA:1.20.1720.10 30 265 6.4E-44 T 12-10-2018 UA74_27435 817469340d757766c8c8ea02d33c9a0e 247 Pfam PF01061 ABC-2 type transporter 10 210 8.5E-11 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_27435 817469340d757766c8c8ea02d33c9a0e 247 PIRSF PIRSF006648 3 245 2.5E-20 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_18835 5903f9bea92fccd693ba842dfb93ad14 394 Gene3D G3DSA:1.10.260.40 2 69 3.3E-14 T 12-10-2018 UA74_18835 5903f9bea92fccd693ba842dfb93ad14 394 SUPERFAMILY SSF47413 5 67 2.67E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_18835 5903f9bea92fccd693ba842dfb93ad14 394 Gene3D G3DSA:1.25.40.10 82 389 1.3E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_18835 5903f9bea92fccd693ba842dfb93ad14 394 SMART SM00530 10 65 5.1E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_18835 5903f9bea92fccd693ba842dfb93ad14 394 SUPERFAMILY SSF48452 155 362 3.8E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_18835 5903f9bea92fccd693ba842dfb93ad14 394 Pfam PF13560 Helix-turn-helix domain 7 64 6.1E-11 T 12-10-2018 UA74_06840 61027c8e829c6bcdcc7f86c9a61b1685 1103 SUPERFAMILY SSF52743 207 492 2.09E-79 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_06840 61027c8e829c6bcdcc7f86c9a61b1685 1103 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 434 444 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_06840 61027c8e829c6bcdcc7f86c9a61b1685 1103 Gene3D G3DSA:3.40.50.200 199 495 3.8E-92 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_06840 61027c8e829c6bcdcc7f86c9a61b1685 1103 Pfam PF00082 Subtilase family 223 483 2.5E-55 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_06840 61027c8e829c6bcdcc7f86c9a61b1685 1103 PRINTS PR00723 Subtilisin serine protease family (S8) signature 433 449 1.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_06840 61027c8e829c6bcdcc7f86c9a61b1685 1103 PRINTS PR00723 Subtilisin serine protease family (S8) signature 261 274 1.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_06840 61027c8e829c6bcdcc7f86c9a61b1685 1103 PRINTS PR00723 Subtilisin serine protease family (S8) signature 223 242 1.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_00195 fcff76f981016095fd41705a9f4c9e4f 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_00195 fcff76f981016095fd41705a9f4c9e4f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_00195 fcff76f981016095fd41705a9f4c9e4f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_00195 fcff76f981016095fd41705a9f4c9e4f 208 Gene3D G3DSA:1.10.357.10 19 205 6.4E-58 T 12-10-2018 UA74_00195 fcff76f981016095fd41705a9f4c9e4f 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 6.9E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_00195 fcff76f981016095fd41705a9f4c9e4f 208 SUPERFAMILY SSF46689 9 90 5.99E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_22180 13ff9657406fdfe4b3f85254bcbd718f 497 Pfam PF01979 Amidohydrolase family 179 470 9.3E-15 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_22180 13ff9657406fdfe4b3f85254bcbd718f 497 Gene3D G3DSA:3.20.20.140 4 101 1.2E-12 T 12-10-2018 UA74_22180 13ff9657406fdfe4b3f85254bcbd718f 497 Gene3D G3DSA:3.20.20.140 154 449 3.4E-82 T 12-10-2018 UA74_22180 13ff9657406fdfe4b3f85254bcbd718f 497 SUPERFAMILY SSF51556 168 455 1.36E-61 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_22180 13ff9657406fdfe4b3f85254bcbd718f 497 Gene3D G3DSA:2.30.40.10 450 481 3.4E-82 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_22180 13ff9657406fdfe4b3f85254bcbd718f 497 SUPERFAMILY SSF51338 4 487 1.39E-16 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 SUPERFAMILY SSF46785 25 94 1.23E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 SMART SM00866 105 243 2.0E-39 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 85 2.0E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 2.2E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 2.2E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 SMART SM00345 30 86 9.5E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 Pfam PF07702 UTRA domain 107 243 6.6E-35 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 Gene3D G3DSA:1.10.10.10 22 90 1.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 SUPERFAMILY SSF64288 74 247 8.17E-46 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_12100 c966cc9b83945adc0f3fa919ab3c4dd4 267 Gene3D G3DSA:3.40.1410.10 91 251 1.1E-43 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 Pfam PF00145 C-5 cytosine-specific DNA methylase 89 251 4.2E-45 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 Pfam PF00145 C-5 cytosine-specific DNA methylase 394 446 8.1E-8 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 Gene3D G3DSA:3.90.120.10 338 439 1.2E-18 T 12-10-2018 UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 89 248 9.2E-43 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 Gene3D G3DSA:3.40.50.150 83 269 2.1E-56 T 12-10-2018 UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 188 202 8.5E-14 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 234 247 8.5E-14 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 88 104 8.5E-14 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 SUPERFAMILY SSF53335 88 446 1.62E-77 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_13955 846b3f2828eb281cbdd47eefcaf2bbda 451 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 150 162 - T 12-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 Gene3D G3DSA:2.170.120.12 48 168 1.0E-83 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 SUPERFAMILY SSF55257 8 220 1.24E-25 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 311 34.804 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 1.7E-25 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 Gene3D G3DSA:3.30.1360.10 12 216 1.0E-83 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 Gene3D G3DSA:1.10.150.20 239 311 2.3E-28 T 12-10-2018 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 243 302 1.4E-25 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 320 2.0E-24 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 SMART SM00662 18 225 5.5E-97 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 SUPERFAMILY SSF47789 246 318 1.02E-23 T 12-10-2018 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 4.6E-114 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 SUPERFAMILY SSF56553 48 169 4.71E-43 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_03140 8b20bb46e53a47ac69536246b5802a4a 352 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.2E-19 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UA74_21725 3366cc0fa41cc8b1d0f657581af6af79 225 Gene3D G3DSA:3.60.15.10 23 223 7.3E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_21725 3366cc0fa41cc8b1d0f657581af6af79 225 SUPERFAMILY SSF56281 27 221 1.96E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_21725 3366cc0fa41cc8b1d0f657581af6af79 225 SMART SM00849 36 204 1.4E-30 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_21725 3366cc0fa41cc8b1d0f657581af6af79 225 Pfam PF00753 Metallo-beta-lactamase superfamily 34 204 6.5E-16 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_18210 39e90e28f09372dec466f89e71f0be3e 495 SUPERFAMILY SSF53901 352 495 1.54E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_18210 39e90e28f09372dec466f89e71f0be3e 495 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 30 225 1.1E-19 T 12-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal UA74_18210 39e90e28f09372dec466f89e71f0be3e 495 Gene3D G3DSA:3.40.47.10 351 495 5.4E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_18210 39e90e28f09372dec466f89e71f0be3e 495 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 357 494 2.2E-15 T 12-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal UA74_18210 39e90e28f09372dec466f89e71f0be3e 495 Gene3D G3DSA:3.40.47.10 28 233 3.4E-66 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_18210 39e90e28f09372dec466f89e71f0be3e 495 SUPERFAMILY SSF53901 25 229 5.57E-50 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_02870 f1f59bb88c54b73b701906c71f54ec45 286 SUPERFAMILY SSF47413 9 72 5.07E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_02870 f1f59bb88c54b73b701906c71f54ec45 286 Gene3D G3DSA:1.10.260.40 8 74 8.4E-8 T 12-10-2018 UA74_02870 f1f59bb88c54b73b701906c71f54ec45 286 Pfam PF13560 Helix-turn-helix domain 13 70 1.1E-8 T 12-10-2018 UA74_02870 f1f59bb88c54b73b701906c71f54ec45 286 SMART SM00530 16 71 1.4E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 SUPERFAMILY SSF54814 2 105 5.76E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 Pfam PF07650 KH domain 37 109 1.1E-17 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 SMART SM00322 59 124 4.9E-7 T 12-10-2018 IPR004087 K Homology domain GO:0003676 UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 37.814 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 8.3E-94 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 5.3E-36 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 Gene3D G3DSA:3.30.1140.32 108 208 9.8E-38 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 SUPERFAMILY SSF54821 109 206 4.19E-35 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 Gene3D G3DSA:3.30.300.20 17 106 5.6E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_02975 5d19069f22c0e2ce883a57493271eef8 280 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_27950 08098b9521b153cb560289b2b0c364de 244 SUPERFAMILY SSF53067 132 226 1.38E-9 T 12-10-2018 UA74_27950 08098b9521b153cb560289b2b0c364de 244 SUPERFAMILY SSF53067 3 107 2.04E-22 T 12-10-2018 UA74_27950 08098b9521b153cb560289b2b0c364de 244 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 228 3.7E-51 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 UA74_27950 08098b9521b153cb560289b2b0c364de 244 Gene3D G3DSA:3.30.420.40 3 228 4.4E-38 T 12-10-2018 UA74_27950 08098b9521b153cb560289b2b0c364de 244 Gene3D G3DSA:3.30.420.40 100 199 4.4E-38 T 12-10-2018 UA74_27950 08098b9521b153cb560289b2b0c364de 244 Pfam PF00814 Glycoprotease family 38 168 1.2E-21 T 12-10-2018 IPR000905 Gcp-like domain UA74_08500 caf63726f8e54ccdbd2a858291983a8b 462 SUPERFAMILY SSF53335 109 456 1.13E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_08500 caf63726f8e54ccdbd2a858291983a8b 462 SUPERFAMILY SSF50249 44 98 7.42E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_08500 caf63726f8e54ccdbd2a858291983a8b 462 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 439 449 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site UA74_08500 caf63726f8e54ccdbd2a858291983a8b 462 Gene3D G3DSA:2.40.50.140 38 116 4.5E-19 T 12-10-2018 UA74_08500 caf63726f8e54ccdbd2a858291983a8b 462 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 382 455 1.2E-8 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 UA74_08500 caf63726f8e54ccdbd2a858291983a8b 462 Gene3D G3DSA:3.40.50.150 117 177 1.9E-5 T 12-10-2018 UA74_08500 caf63726f8e54ccdbd2a858291983a8b 462 Pfam PF01938 TRAM domain 47 93 4.2E-10 T 12-10-2018 IPR002792 TRAM domain UA74_08500 caf63726f8e54ccdbd2a858291983a8b 462 Gene3D G3DSA:3.40.50.150 246 455 5.2E-45 T 12-10-2018 UA74_28810 e0b9b04ef1a2cd5c93741ef5a95e1b9d 386 Gene3D G3DSA:2.20.25.520 1 56 1.6E-13 T 12-10-2018 IPR038576 Methyltransferase putative zinc binding domain superfamily UA74_28810 e0b9b04ef1a2cd5c93741ef5a95e1b9d 386 Gene3D G3DSA:3.40.50.720 270 361 1.3E-18 T 12-10-2018 UA74_28810 e0b9b04ef1a2cd5c93741ef5a95e1b9d 386 SUPERFAMILY SSF53335 118 214 6.58E-10 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_28810 e0b9b04ef1a2cd5c93741ef5a95e1b9d 386 Pfam PF08421 Putative zinc binding domain 6 58 9.2E-13 T 12-10-2018 IPR013630 Methyltransferase putative zinc binding domain UA74_28810 e0b9b04ef1a2cd5c93741ef5a95e1b9d 386 Gene3D G3DSA:3.40.50.150 78 216 1.1E-9 T 12-10-2018 UA74_28810 e0b9b04ef1a2cd5c93741ef5a95e1b9d 386 Pfam PF08484 C-methyltransferase C-terminal domain 210 360 2.2E-25 T 12-10-2018 IPR013691 C-methyltransferase UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 SMART SM01134 74 236 2.8E-60 T 12-10-2018 UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 SMART SM00420 6 58 3.5E-18 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 SUPERFAMILY SSF100950 75 236 2.22E-34 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 SUPERFAMILY SSF46785 5 59 4.89E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 Pfam PF00455 DeoR C terminal sensor domain 76 234 1.1E-47 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 8.3E-17 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.8E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.8E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_18335 68e424a6f79dde3e3774d6e305791b8d 267 Gene3D G3DSA:1.10.10.10 2 55 4.7E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10995 ff65dc5a6ff42a7f80b42c5f8ed13739 142 PIRSF PIRSF016602 1 139 5.8E-53 T 12-10-2018 IPR016672 Polyketide biosynthesis protein CurC, predicted UA74_10995 ff65dc5a6ff42a7f80b42c5f8ed13739 142 SUPERFAMILY SSF51182 20 134 2.97E-27 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_10995 ff65dc5a6ff42a7f80b42c5f8ed13739 142 Gene3D G3DSA:2.60.120.10 16 119 5.9E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_10995 ff65dc5a6ff42a7f80b42c5f8ed13739 142 Pfam PF07883 Cupin domain 45 107 5.0E-17 T 12-10-2018 IPR013096 Cupin 2, conserved barrel UA74_21225 1e95a3d578e76a0ac4d62cf817ab9082 240 SUPERFAMILY SSF53474 10 211 9.76E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_21225 1e95a3d578e76a0ac4d62cf817ab9082 240 Pfam PF12697 Alpha/beta hydrolase family 30 217 5.7E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_21225 1e95a3d578e76a0ac4d62cf817ab9082 240 Gene3D G3DSA:3.40.50.1820 8 217 1.2E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_30070 46c927a631ab12c349ba0f12fd98a21f 396 Pfam PF00487 Fatty acid desaturase 112 370 8.3E-40 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_30070 46c927a631ab12c349ba0f12fd98a21f 396 PIRSF PIRSF015921 4 396 3.5E-78 T 12-10-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 UA74_04410 92a90fe644a7aafe4cd4dcf2257d25b5 370 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 14 368 4.4E-169 T 12-10-2018 IPR019880 4-dedimethylamino-4-oxo-anhydrotetracycline transaminase OxyQ UA74_04410 92a90fe644a7aafe4cd4dcf2257d25b5 370 Gene3D G3DSA:3.40.640.10 48 274 2.0E-77 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_04410 92a90fe644a7aafe4cd4dcf2257d25b5 370 Gene3D G3DSA:3.90.1150.10 22 360 2.0E-77 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_04410 92a90fe644a7aafe4cd4dcf2257d25b5 370 Pfam PF00155 Aminotransferase class I and II 37 367 1.4E-42 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_04410 92a90fe644a7aafe4cd4dcf2257d25b5 370 SUPERFAMILY SSF53383 25 368 2.26E-77 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_04410 92a90fe644a7aafe4cd4dcf2257d25b5 370 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 225 238 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UA74_11205 22ac92a2c2c9aecd52373901ee6f8b60 287 SMART SM00530 16 71 6.7E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_11205 22ac92a2c2c9aecd52373901ee6f8b60 287 Pfam PF13560 Helix-turn-helix domain 12 73 1.2E-11 T 12-10-2018 UA74_11205 22ac92a2c2c9aecd52373901ee6f8b60 287 Gene3D G3DSA:1.10.260.40 3 76 2.0E-10 T 12-10-2018 UA74_11205 22ac92a2c2c9aecd52373901ee6f8b60 287 SUPERFAMILY SSF47413 9 72 1.69E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 Gene3D G3DSA:2.10.230.10 146 210 1.4E-31 T 12-10-2018 UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 Pfam PF00684 DnaJ central domain 146 210 4.9E-12 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 SUPERFAMILY SSF49493 114 266 6.15E-17 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 SUPERFAMILY SSF46565 3 102 4.97E-30 T 12-10-2018 IPR036869 Chaperone J-domain superfamily UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 Gene3D G3DSA:1.10.287.110 1 112 1.2E-28 T 12-10-2018 IPR036869 Chaperone J-domain superfamily UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 PRINTS PR00625 DnaJ domain signature 6 24 1.0E-21 T 12-10-2018 IPR001623 DnaJ domain UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 PRINTS PR00625 DnaJ domain signature 60 79 1.0E-21 T 12-10-2018 IPR001623 DnaJ domain UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 PRINTS PR00625 DnaJ domain signature 40 60 1.0E-21 T 12-10-2018 IPR001623 DnaJ domain UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 PRINTS PR00625 DnaJ domain signature 24 39 1.0E-21 T 12-10-2018 IPR001623 DnaJ domain UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 SUPERFAMILY SSF57938 133 213 2.22E-17 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 SUPERFAMILY SSF49493 262 351 1.7E-19 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 383 36.605 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 Gene3D G3DSA:2.60.260.20 116 252 1.4E-31 T 12-10-2018 UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 Pfam PF00226 DnaJ domain 4 65 4.6E-23 T 12-10-2018 IPR001623 DnaJ domain UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 SMART SM00271 3 60 5.3E-28 T 12-10-2018 IPR001623 DnaJ domain UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 Pfam PF01556 DnaJ C terminal domain 121 340 3.0E-36 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal UA74_24510 18cb84c264fbc5e97a3557fe48d9ef96 387 Gene3D G3DSA:2.60.260.20 257 370 2.8E-28 T 12-10-2018 UA74_14865 5e6cc778584e67b48c7ef9ad61f67449 605 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_14865 5e6cc778584e67b48c7ef9ad61f67449 605 SUPERFAMILY SSF52540 376 564 2.25E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14865 5e6cc778584e67b48c7ef9ad61f67449 605 Pfam PF00005 ABC transporter 391 496 6.5E-8 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_14865 5e6cc778584e67b48c7ef9ad61f67449 605 SUPERFAMILY SSF90123 20 335 6.02E-49 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_14865 5e6cc778584e67b48c7ef9ad61f67449 605 Gene3D G3DSA:3.40.50.300 346 576 5.0E-45 T 12-10-2018 UA74_14865 5e6cc778584e67b48c7ef9ad61f67449 605 Gene3D G3DSA:1.20.1560.10 8 335 1.5E-42 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_14865 5e6cc778584e67b48c7ef9ad61f67449 605 Pfam PF00664 ABC transporter transmembrane region 45 302 3.1E-23 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_16010 1148fc31e7df8aa9c42cdad05430d64d 136 Pfam PF00239 Resolvase, N terminal domain 35 119 6.9E-6 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 UA74_16010 1148fc31e7df8aa9c42cdad05430d64d 136 Gene3D G3DSA:3.40.50.1390 30 130 8.9E-6 T 12-10-2018 UA74_15225 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00412 Epoxide hydrolase signature 119 132 3.7E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15225 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00412 Epoxide hydrolase signature 233 249 3.7E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15225 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00412 Epoxide hydrolase signature 266 288 3.7E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15225 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00412 Epoxide hydrolase signature 61 76 3.7E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15225 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 2.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15225 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 235 249 2.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15225 a7212357da86b52ba283095cb60eebea 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 2.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15225 a7212357da86b52ba283095cb60eebea 296 Pfam PF00561 alpha/beta hydrolase fold 35 276 3.5E-29 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15225 a7212357da86b52ba283095cb60eebea 296 Gene3D G3DSA:3.40.50.1820 7 295 2.1E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15225 a7212357da86b52ba283095cb60eebea 296 SUPERFAMILY SSF53474 9 286 6.38E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17325 2fbe1ca757571a2dbe91819096b798e1 519 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 433 3.7E-81 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UA74_17325 2fbe1ca757571a2dbe91819096b798e1 519 Gene3D G3DSA:1.20.1720.10 25 238 7.6E-42 T 12-10-2018 UA74_17325 2fbe1ca757571a2dbe91819096b798e1 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 119 139 3.5E-8 T 12-10-2018 UA74_17325 2fbe1ca757571a2dbe91819096b798e1 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 3.5E-8 T 12-10-2018 UA74_17325 2fbe1ca757571a2dbe91819096b798e1 519 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 3.5E-8 T 12-10-2018 UA74_17325 2fbe1ca757571a2dbe91819096b798e1 519 Gene3D G3DSA:1.20.1250.20 279 481 1.8E-19 T 12-10-2018 UA74_17325 2fbe1ca757571a2dbe91819096b798e1 519 SUPERFAMILY SSF103473 14 480 3.14E-62 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_17325 2fbe1ca757571a2dbe91819096b798e1 519 Pfam PF07690 Major Facilitator Superfamily 30 426 1.9E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_21265 dbc5a8dd2bd76e76eddd85b72fa420e4 712 Pfam PF00912 Transglycosylase 72 260 2.7E-57 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_21265 dbc5a8dd2bd76e76eddd85b72fa420e4 712 Gene3D G3DSA:3.40.710.10 307 711 1.7E-73 T 12-10-2018 UA74_21265 dbc5a8dd2bd76e76eddd85b72fa420e4 712 Pfam PF00905 Penicillin binding protein transpeptidase domain 377 637 2.3E-23 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_21265 dbc5a8dd2bd76e76eddd85b72fa420e4 712 SUPERFAMILY SSF53955 61 277 1.18E-60 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_21265 dbc5a8dd2bd76e76eddd85b72fa420e4 712 SUPERFAMILY SSF56601 242 709 2.91E-77 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_21265 dbc5a8dd2bd76e76eddd85b72fa420e4 712 Gene3D G3DSA:1.10.3810.10 64 276 3.0E-65 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_11345 dd9efff6c48ceb4d9acf5ca3739c0565 154 SUPERFAMILY SSF47413 45 85 4.07E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_11345 dd9efff6c48ceb4d9acf5ca3739c0565 154 Gene3D G3DSA:1.10.260.40 6 138 4.6E-47 T 12-10-2018 UA74_00215 8e8053613bf252ccbb536a0626df67ac 457 Pfam PF01381 Helix-turn-helix 35 83 7.0E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_00215 8e8053613bf252ccbb536a0626df67ac 457 SUPERFAMILY SSF47413 33 85 5.93E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_00215 8e8053613bf252ccbb536a0626df67ac 457 Gene3D G3DSA:1.10.260.40 11 84 5.7E-9 T 12-10-2018 UA74_00215 8e8053613bf252ccbb536a0626df67ac 457 SUPERFAMILY SSF48452 211 327 7.32E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_00215 8e8053613bf252ccbb536a0626df67ac 457 SMART SM00530 32 87 1.3E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_00215 8e8053613bf252ccbb536a0626df67ac 457 Gene3D G3DSA:1.25.40.10 190 418 8.0E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_20380 7958d8e973e40cd0f8ef91c3078ecc7a 493 SUPERFAMILY SSF56112 97 413 5.25E-26 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_20380 7958d8e973e40cd0f8ef91c3078ecc7a 493 Gene3D G3DSA:1.10.510.10 319 417 8.7E-29 T 12-10-2018 UA74_20380 7958d8e973e40cd0f8ef91c3078ecc7a 493 Gene3D G3DSA:3.30.200.20 96 198 3.1E-9 T 12-10-2018 UA74_20380 7958d8e973e40cd0f8ef91c3078ecc7a 493 Pfam PF01636 Phosphotransferase enzyme family 126 394 1.4E-11 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_13170 dfcdf7325c4ddbccc5cedd0b2155e27c 145 Gene3D G3DSA:3.30.530.20 2 144 4.2E-23 T 12-10-2018 IPR023393 START-like domain superfamily UA74_13170 dfcdf7325c4ddbccc5cedd0b2155e27c 145 SUPERFAMILY SSF55961 1 142 8.45E-17 T 12-10-2018 UA74_13170 dfcdf7325c4ddbccc5cedd0b2155e27c 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 141 3.2E-7 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase UA74_22870 b3aff44fc459127ff6f6b734bfd3e447 244 Gene3D G3DSA:1.10.10.60 4 77 3.8E-27 T 12-10-2018 UA74_22870 b3aff44fc459127ff6f6b734bfd3e447 244 Gene3D G3DSA:1.10.357.10 79 234 7.2E-34 T 12-10-2018 UA74_22870 b3aff44fc459127ff6f6b734bfd3e447 244 SUPERFAMILY SSF46689 19 81 3.49E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_22870 b3aff44fc459127ff6f6b734bfd3e447 244 SUPERFAMILY SSF48498 90 233 1.78E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_22870 b3aff44fc459127ff6f6b734bfd3e447 244 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 72 5.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22870 b3aff44fc459127ff6f6b734bfd3e447 244 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 84 232 8.7E-19 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_06060 9e9a4904b071cecccbe4af472a4537b5 376 Pfam PF00226 DnaJ domain 3 61 1.3E-16 T 12-10-2018 IPR001623 DnaJ domain UA74_06060 9e9a4904b071cecccbe4af472a4537b5 376 Pfam PF08378 Nuclease-related domain 219 288 9.1E-5 T 12-10-2018 IPR011528 Nuclease-related domain, NERD UA74_06060 9e9a4904b071cecccbe4af472a4537b5 376 ProSitePatterns PS00636 Nt-dnaJ domain signature. 41 60 - T 12-10-2018 IPR018253 DnaJ domain, conserved site UA74_06060 9e9a4904b071cecccbe4af472a4537b5 376 SUPERFAMILY SSF46565 1 65 2.75E-22 T 12-10-2018 IPR036869 Chaperone J-domain superfamily UA74_06060 9e9a4904b071cecccbe4af472a4537b5 376 PRINTS PR00625 DnaJ domain signature 23 38 3.7E-7 T 12-10-2018 IPR001623 DnaJ domain UA74_06060 9e9a4904b071cecccbe4af472a4537b5 376 PRINTS PR00625 DnaJ domain signature 5 23 3.7E-7 T 12-10-2018 IPR001623 DnaJ domain UA74_06060 9e9a4904b071cecccbe4af472a4537b5 376 SMART SM00271 2 56 8.7E-18 T 12-10-2018 IPR001623 DnaJ domain UA74_06060 9e9a4904b071cecccbe4af472a4537b5 376 Gene3D G3DSA:1.10.287.110 1 72 1.7E-20 T 12-10-2018 IPR036869 Chaperone J-domain superfamily UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 Gene3D G3DSA:1.10.287.130 181 295 8.6E-22 T 12-10-2018 UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 SUPERFAMILY SSF47384 212 295 3.73E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 SMART SM00387 334 444 2.6E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 SUPERFAMILY SSF55874 284 442 1.96E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 Gene3D G3DSA:3.30.565.10 299 444 7.6E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 1.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 383 1.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 397 1.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 1.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 230 294 5.6E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 SMART SM00388 229 294 9.8E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_04350 73f8da7de50097f9898ab97e6eeb6bea 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 442 4.3E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_01095 46987ff57d9078e202d01a3238c1429c 365 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 154 349 2.0E-45 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_01095 46987ff57d9078e202d01a3238c1429c 365 Gene3D G3DSA:3.40.50.720 19 360 3.3E-125 T 12-10-2018 UA74_01095 46987ff57d9078e202d01a3238c1429c 365 PIRSF PIRSF000148 15 365 1.1E-107 T 12-10-2018 UA74_01095 46987ff57d9078e202d01a3238c1429c 365 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 18 364 1.3E-115 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UA74_01095 46987ff57d9078e202d01a3238c1429c 365 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 15 363 32.371 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UA74_01095 46987ff57d9078e202d01a3238c1429c 365 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 18 131 3.6E-27 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UA74_01095 46987ff57d9078e202d01a3238c1429c 365 Gene3D G3DSA:3.30.360.10 141 346 3.3E-125 T 12-10-2018 UA74_01095 46987ff57d9078e202d01a3238c1429c 365 SUPERFAMILY SSF55347 142 350 9.82E-66 T 12-10-2018 UA74_01095 46987ff57d9078e202d01a3238c1429c 365 SMART SM00859 17 133 1.1E-35 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UA74_01095 46987ff57d9078e202d01a3238c1429c 365 SUPERFAMILY SSF51735 17 169 2.49E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_01555 48472380315195a9d49d1ccdf398577f 280 Pfam PF00809 Pterin binding enzyme 14 259 8.0E-83 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_01555 48472380315195a9d49d1ccdf398577f 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 12 273 9.3E-89 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 UA74_01555 48472380315195a9d49d1ccdf398577f 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 13 28 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_01555 48472380315195a9d49d1ccdf398577f 280 Gene3D G3DSA:3.20.20.20 2 279 1.6E-102 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_01555 48472380315195a9d49d1ccdf398577f 280 SUPERFAMILY SSF51717 11 275 1.31E-89 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_01555 48472380315195a9d49d1ccdf398577f 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 47 60 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UA74_29825 1796fb736d482f9d448a1269db782025 290 SUPERFAMILY SSF63380 8 132 5.78E-9 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_29825 1796fb736d482f9d448a1269db782025 290 Pfam PF08021 Siderophore-interacting FAD-binding domain 10 130 1.7E-28 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting UA74_29825 1796fb736d482f9d448a1269db782025 290 Gene3D G3DSA:3.40.50.80 144 284 4.4E-40 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_29825 1796fb736d482f9d448a1269db782025 290 Gene3D G3DSA:2.40.30.10 1 131 1.4E-34 T 12-10-2018 UA74_29825 1796fb736d482f9d448a1269db782025 290 Pfam PF04954 Siderophore-interacting protein 149 265 5.6E-35 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain UA74_00090 8ce6c2a475ecb9a273159f8689c16e6a 246 SUPERFAMILY SSF144091 15 199 1.57E-42 T 12-10-2018 UA74_00090 8ce6c2a475ecb9a273159f8689c16e6a 246 Gene3D G3DSA:1.20.1540.10 11 205 1.1E-38 T 12-10-2018 IPR035952 Rhomboid-like superfamily UA74_00090 8ce6c2a475ecb9a273159f8689c16e6a 246 Pfam PF01694 Rhomboid family 60 190 2.6E-28 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 UA74_16890 a67be91bff42a111357a0b64f59a2af7 128 Gene3D G3DSA:3.10.450.50 5 128 4.6E-36 T 12-10-2018 UA74_16890 a67be91bff42a111357a0b64f59a2af7 128 SUPERFAMILY SSF54427 27 126 1.88E-32 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_16890 a67be91bff42a111357a0b64f59a2af7 128 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 3 126 26.472 T 12-10-2018 IPR023006 Uncharacterised protein family UPF0225 UA74_21425 32f400b68e76580482d8515a0a8a2b0d 495 SUPERFAMILY SSF53474 97 481 3.31E-18 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_21425 32f400b68e76580482d8515a0a8a2b0d 495 Pfam PF08386 TAP-like protein 403 493 1.7E-19 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal UA74_19430 9e1e00015690564b99f378d4373ddd83 384 Gene3D G3DSA:3.40.50.300 75 251 2.4E-23 T 12-10-2018 UA74_19430 9e1e00015690564b99f378d4373ddd83 384 SMART SM00382 91 247 1.9E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_19430 9e1e00015690564b99f378d4373ddd83 384 SUPERFAMILY SSF52540 72 288 8.77E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19430 9e1e00015690564b99f378d4373ddd83 384 Pfam PF07728 AAA domain (dynein-related subfamily) 95 237 4.3E-35 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 UA74_30220 27b95cf37fe2bd5f3b3bb7d4f694eb74 147 PRINTS PR00502 NUDIX hydrolase family signature 37 52 9.2E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_30220 27b95cf37fe2bd5f3b3bb7d4f694eb74 147 PRINTS PR00502 NUDIX hydrolase family signature 23 37 9.2E-8 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_30220 27b95cf37fe2bd5f3b3bb7d4f694eb74 147 SUPERFAMILY SSF55811 16 124 1.49E-30 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_30220 27b95cf37fe2bd5f3b3bb7d4f694eb74 147 ProSitePatterns PS00893 Nudix box signature. 28 49 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_30220 27b95cf37fe2bd5f3b3bb7d4f694eb74 147 Gene3D G3DSA:3.90.79.10 5 130 3.9E-32 T 12-10-2018 UA74_30220 27b95cf37fe2bd5f3b3bb7d4f694eb74 147 Pfam PF00293 NUDIX domain 19 122 7.8E-21 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_01490 a590f20ba11e2a78d111e39e0a9244ad 260 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 65 80 1.2E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_01490 a590f20ba11e2a78d111e39e0a9244ad 260 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 117 131 1.2E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_01490 a590f20ba11e2a78d111e39e0a9244ad 260 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 203 215 1.2E-12 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_01490 a590f20ba11e2a78d111e39e0a9244ad 260 SMART SM00020 36 254 1.3E-38 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_01490 a590f20ba11e2a78d111e39e0a9244ad 260 Pfam PF00089 Trypsin 37 254 2.7E-36 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_01490 a590f20ba11e2a78d111e39e0a9244ad 260 SUPERFAMILY SSF50494 22 258 1.38E-47 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_01490 a590f20ba11e2a78d111e39e0a9244ad 260 Gene3D G3DSA:2.40.10.10 29 259 8.7E-38 T 12-10-2018 UA74_00870 0b176f756f7d38773bda6b3b0499cfbc 206 Pfam PF04542 Sigma-70 region 2 41 110 2.3E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_00870 0b176f756f7d38773bda6b3b0499cfbc 206 Gene3D G3DSA:1.10.10.10 129 204 3.6E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_00870 0b176f756f7d38773bda6b3b0499cfbc 206 Gene3D G3DSA:1.10.1740.10 30 124 1.3E-19 T 12-10-2018 UA74_00870 0b176f756f7d38773bda6b3b0499cfbc 206 SUPERFAMILY SSF88659 140 202 2.24E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_00870 0b176f756f7d38773bda6b3b0499cfbc 206 Pfam PF08281 Sigma-70, region 4 148 198 5.1E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_00870 0b176f756f7d38773bda6b3b0499cfbc 206 SUPERFAMILY SSF88946 36 119 1.41E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_00870 0b176f756f7d38773bda6b3b0499cfbc 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 202 1.9E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_12495 46879b65a48c82fd1985c5cb95bc152f 336 Pfam PF02628 Cytochrome oxidase assembly protein 28 203 1.8E-13 T 12-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 UA74_10195 0d4beebb72d2a633c627f641a9106e3c 237 Gene3D G3DSA:2.160.10.10 17 219 9.9E-54 T 12-10-2018 UA74_10195 0d4beebb72d2a633c627f641a9106e3c 237 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 130 164 6.1E-8 T 12-10-2018 IPR001451 Hexapeptide repeat UA74_10195 0d4beebb72d2a633c627f641a9106e3c 237 SUPERFAMILY SSF51161 53 216 1.18E-43 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily UA74_24650 26b4090f11f22285084a1e4d76791b34 168 SUPERFAMILY SSF55826 12 159 5.89E-33 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UA74_24650 26b4090f11f22285084a1e4d76791b34 168 Gene3D G3DSA:3.90.960.10 5 164 9.0E-41 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UA74_24650 26b4090f11f22285084a1e4d76791b34 168 Pfam PF04073 Aminoacyl-tRNA editing domain 33 151 6.3E-27 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_18370 8c084654ae90ab312dcf009abbd24aff 104 Pfam PF00754 F5/8 type C domain 7 98 4.7E-7 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_18370 8c084654ae90ab312dcf009abbd24aff 104 Gene3D G3DSA:2.60.120.260 2 104 1.3E-13 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_18370 8c084654ae90ab312dcf009abbd24aff 104 SUPERFAMILY SSF49785 3 101 4.95E-11 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 SUPERFAMILY SSF55785 204 330 9.99E-21 T 12-10-2018 IPR035965 PAS domain superfamily UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 Pfam PF00989 PAS fold 218 328 5.7E-10 T 12-10-2018 IPR013767 PAS fold GO:0006355 UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 SUPERFAMILY SSF55073 348 506 2.59E-33 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 Gene3D G3DSA:3.20.20.450 515 772 6.9E-56 T 12-10-2018 IPR035919 EAL domain superfamily UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 SMART SM00091 217 283 6.8E-12 T 12-10-2018 IPR000014 PAS domain UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 Gene3D G3DSA:3.30.450.20 207 330 1.5E-19 T 12-10-2018 UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 341 501 4.7E-27 T 12-10-2018 IPR000160 GGDEF domain UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 213 331 1.2E-13 T 12-10-2018 IPR000014 PAS domain UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 Gene3D G3DSA:3.30.70.270 337 510 1.6E-37 T 12-10-2018 UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 SMART SM00267 332 504 7.8E-35 T 12-10-2018 IPR000160 GGDEF domain UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 Pfam PF00990 Diguanylate cyclase, GGDEF domain 344 499 9.4E-30 T 12-10-2018 IPR000160 GGDEF domain UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 SMART SM00052 514 762 1.2E-34 T 12-10-2018 IPR001633 EAL domain UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 Pfam PF00563 EAL domain 522 757 5.0E-43 T 12-10-2018 IPR001633 EAL domain UA74_28135 6896b0e00922552b91a3e52d2cb459d2 778 SUPERFAMILY SSF141868 523 769 2.88E-44 T 12-10-2018 IPR035919 EAL domain superfamily UA74_28420 250765e10233b7205b97471d6e82383a 366 Gene3D G3DSA:3.90.1170.40 220 364 3.5E-39 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 UA74_28420 250765e10233b7205b97471d6e82383a 366 Gene3D G3DSA:3.40.980.10 8 167 2.7E-48 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily UA74_28420 250765e10233b7205b97471d6e82383a 366 Pfam PF02391 MoaE protein 236 346 2.9E-29 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 UA74_28420 250765e10233b7205b97471d6e82383a 366 SUPERFAMILY SSF54690 236 364 1.15E-33 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 UA74_28420 250765e10233b7205b97471d6e82383a 366 SMART SM00852 14 156 2.1E-15 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_28420 250765e10233b7205b97471d6e82383a 366 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 149 9.3E-29 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_28420 250765e10233b7205b97471d6e82383a 366 Pfam PF00994 Probable molybdopterin binding domain 15 151 5.8E-25 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_28420 250765e10233b7205b97471d6e82383a 366 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 72 85 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 UA74_28420 250765e10233b7205b97471d6e82383a 366 SUPERFAMILY SSF53218 13 161 4.32E-36 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily UA74_18920 ca977772b1f5e2f8938bca8ab664ccab 355 Gene3D G3DSA:3.20.20.70 74 329 1.3E-6 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_18920 ca977772b1f5e2f8938bca8ab664ccab 355 Pfam PF04055 Radical SAM superfamily 77 253 3.5E-11 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_18920 ca977772b1f5e2f8938bca8ab664ccab 355 SUPERFAMILY SSF102114 76 290 6.28E-12 T 12-10-2018 UA74_18920 ca977772b1f5e2f8938bca8ab664ccab 355 SMART SM00729 73 299 0.0044 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_16740 21cb05204d62663489f32d03150232aa 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_16740 21cb05204d62663489f32d03150232aa 262 Pfam PF00106 short chain dehydrogenase 2 183 1.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16740 21cb05204d62663489f32d03150232aa 262 Gene3D G3DSA:3.40.50.720 1 236 9.7E-49 T 12-10-2018 UA74_16740 21cb05204d62663489f32d03150232aa 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 3.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16740 21cb05204d62663489f32d03150232aa 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 3.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16740 21cb05204d62663489f32d03150232aa 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 3.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16740 21cb05204d62663489f32d03150232aa 262 SUPERFAMILY SSF51735 2 243 1.55E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_16740 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16740 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16740 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 1.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16740 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16740 21cb05204d62663489f32d03150232aa 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.3E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 SMART SM00382 349 477 3.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 Gene3D G3DSA:3.40.50.300 306 481 3.2E-52 T 12-10-2018 UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 Gene3D G3DSA:1.10.1750.10 557 657 4.2E-36 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 SUPERFAMILY SSF48295 548 653 1.12E-34 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 SUPERFAMILY SSF52540 316 528 1.38E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 Gene3D G3DSA:3.30.300.180 5 86 3.5E-9 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 SMART SM00760 561 630 6.8E-34 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 ProSitePatterns PS01008 DnaA protein signature. 611 630 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 301 651 5.4E-149 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 Pfam PF00308 Bacterial dnaA protein 317 534 8.6E-102 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 Gene3D G3DSA:1.10.8.60 483 553 5.1E-25 T 12-10-2018 UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 564 630 5.9E-28 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 652 32.897 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 382 396 1.8E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 448 475 1.8E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 414 428 1.8E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 611 630 1.8E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 350 370 1.8E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UA74_00005 25b8c4755b06bb017d31fc818e8ed80f 657 Pfam PF11638 DnaA N-terminal domain 11 62 1.1E-5 T 12-10-2018 IPR024633 DnaA N-terminal domain UA74_10265 7b10cd7da70a43a3107525acd0ba3044 447 Gene3D G3DSA:1.10.10.10 126 175 1.1E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10265 7b10cd7da70a43a3107525acd0ba3044 447 Gene3D G3DSA:1.10.1740.10 1 76 1.4E-6 T 12-10-2018 UA74_10265 7b10cd7da70a43a3107525acd0ba3044 447 Pfam PF04542 Sigma-70 region 2 21 80 1.1E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_10265 7b10cd7da70a43a3107525acd0ba3044 447 Pfam PF08281 Sigma-70, region 4 121 171 1.1E-9 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_10265 7b10cd7da70a43a3107525acd0ba3044 447 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 172 2.3E-14 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_10265 7b10cd7da70a43a3107525acd0ba3044 447 SUPERFAMILY SSF88659 111 172 2.24E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_10265 7b10cd7da70a43a3107525acd0ba3044 447 SUPERFAMILY SSF88946 5 87 3.61E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_19525 04806bda3711713adbe64164c907043f 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 316 3.2E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_19525 04806bda3711713adbe64164c907043f 320 Gene3D G3DSA:1.10.3720.10 79 317 4.0E-68 T 12-10-2018 IPR035906 MetI-like superfamily UA74_19525 04806bda3711713adbe64164c907043f 320 SUPERFAMILY SSF161098 81 308 1.14E-62 T 12-10-2018 IPR035906 MetI-like superfamily UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 8 131 1.0E-25 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 146 210 2.8E-5 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 SUPERFAMILY SSF53254 7 225 2.57E-69 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 10 19 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 7 250 4.9E-108 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 SMART SM00855 7 192 7.9E-23 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 Gene3D G3DSA:3.40.50.1240 3 246 4.3E-80 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 5 233 42.307 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 PIRSF PIRSF000709 5 114 0.004 T 12-10-2018 UA74_02230 75eac3ce109d9731819ae1a9d6389208 250 PIRSF PIRSF000709 141 218 0.0065 T 12-10-2018 UA74_23670 c0538684679ef1487481ec39de5f88eb 365 Gene3D G3DSA:2.40.50.140 201 341 5.8E-27 T 12-10-2018 UA74_23670 c0538684679ef1487481ec39de5f88eb 365 Gene3D G3DSA:3.30.470.30 8 199 1.4E-39 T 12-10-2018 UA74_23670 c0538684679ef1487481ec39de5f88eb 365 Pfam PF04679 ATP dependent DNA ligase C terminal region 221 333 5.4E-16 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 UA74_23670 c0538684679ef1487481ec39de5f88eb 365 SUPERFAMILY SSF56091 7 199 6.48E-43 T 12-10-2018 UA74_23670 c0538684679ef1487481ec39de5f88eb 365 Pfam PF01068 ATP dependent DNA ligase domain 11 199 1.5E-31 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 UA74_23670 c0538684679ef1487481ec39de5f88eb 365 SUPERFAMILY SSF50249 202 339 1.63E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_09050 90ad913d5b1e56524c8279df46fdd9eb 126 SUPERFAMILY SSF88723 1 124 4.49E-21 T 12-10-2018 IPR029060 PIN-like domain superfamily UA74_09050 90ad913d5b1e56524c8279df46fdd9eb 126 Pfam PF01850 PIN domain 3 118 3.9E-15 T 12-10-2018 IPR002716 PIN domain UA74_09050 90ad913d5b1e56524c8279df46fdd9eb 126 Gene3D G3DSA:3.40.50.1010 1 123 6.0E-11 T 12-10-2018 UA74_15295 00f08312b1819b81bd05da1a32187397 503 Gene3D G3DSA:1.20.1720.10 8 212 3.5E-38 T 12-10-2018 UA74_15295 00f08312b1819b81bd05da1a32187397 503 Pfam PF07690 Major Facilitator Superfamily 13 402 1.3E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_15295 00f08312b1819b81bd05da1a32187397 503 Gene3D G3DSA:1.20.1250.20 259 486 2.0E-19 T 12-10-2018 UA74_15295 00f08312b1819b81bd05da1a32187397 503 SUPERFAMILY SSF103473 3 491 3.27E-61 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_17540 7488988146acce9411be7495a113c966 420 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 274 285 8.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 137 153 8.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 154 169 8.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 320 335 8.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 91 102 8.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 292 319 8.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 193 215 8.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 342 351 8.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 PRINTS PR00359 B-class P450 signature 351 362 8.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 Pfam PF00067 Cytochrome P450 207 372 1.7E-24 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 SUPERFAMILY SSF48264 14 404 1.83E-95 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17540 7488988146acce9411be7495a113c966 420 Gene3D G3DSA:1.10.630.10 7 411 1.7E-129 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Gene3D G3DSA:3.30.2060.10 150 237 3.7E-57 T 12-10-2018 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Pfam PF00271 Helicase conserved C-terminal domain 853 952 9.2E-15 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Pfam PF02559 CarD-like/TRCF domain 519 618 1.1E-30 T 12-10-2018 IPR003711 CarD-like/TRCF domain UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Pfam PF03461 TRCF domain 1055 1150 1.1E-17 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SMART SM00490 869 953 9.1E-18 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SUPERFAMILY SSF52540 397 505 6.64E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SMART SM00982 1054 1164 7.4E-33 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Gene3D G3DSA:3.40.50.300 585 824 2.4E-228 T 12-10-2018 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SMART SM01058 518 619 1.0E-46 T 12-10-2018 IPR003711 CarD-like/TRCF domain UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 43 1164 27.25 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SUPERFAMILY SSF52540 569 826 2.09E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Gene3D G3DSA:2.30.30.840 522 584 2.4E-228 T 12-10-2018 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SUPERFAMILY SSF52540 25 371 2.07E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SMART SM00487 643 839 1.7E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Pfam PF00270 DEAD/DEAH box helicase 668 809 1.7E-16 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SUPERFAMILY SSF143517 1041 1215 1.57E-28 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Gene3D G3DSA:3.40.50.11180 53 317 3.7E-57 T 12-10-2018 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Gene3D G3DSA:3.90.1150.50 1050 1174 4.8E-18 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SUPERFAMILY SSF141259 511 591 3.92E-18 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 Gene3D G3DSA:3.40.50.300 519 1031 2.4E-228 T 12-10-2018 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 167 1140 0.0 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 UA74_03675 25d190a5bfc83d115e88f324d25a54f0 1228 SUPERFAMILY SSF52540 825 1032 2.54E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 6 272 1.5E-95 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Pfam PF01039 Carboxyl transferase domain 90 234 4.2E-17 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 305 391 9.4E-32 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Gene3D G3DSA:3.90.226.10 21 274 2.5E-78 T 12-10-2018 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 224 235 6.7E-34 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 158 176 6.7E-34 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 124 138 6.7E-34 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 246 255 6.7E-34 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 195 212 6.7E-34 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 SUPERFAMILY SSF52096 302 559 2.42E-76 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 253 560 37.283 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Gene3D G3DSA:3.90.226.10 299 560 2.1E-87 T 12-10-2018 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 2 276 34.497 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UA74_11040 713f4b1b983c0bc3d8a3a53b04d2fdbe 571 SUPERFAMILY SSF52096 21 269 2.08E-72 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_01810 cc8b769758873e352606f063a525977c 472 Pfam PF12821 Threonine/Serine exporter, ThrE 311 439 7.4E-18 T 12-10-2018 IPR024528 Threonine/Serine exporter, ThrE UA74_01810 cc8b769758873e352606f063a525977c 472 Pfam PF06738 Putative threonine/serine exporter 42 285 7.7E-58 T 12-10-2018 IPR010619 Putative threonine/serine exporter UA74_14850 303f8083c1e39c2cbf81241f5de75a9f 308 Pfam PF01636 Phosphotransferase enzyme family 29 258 8.3E-36 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_14850 303f8083c1e39c2cbf81241f5de75a9f 308 SUPERFAMILY SSF56112 1 269 3.21E-44 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_14850 303f8083c1e39c2cbf81241f5de75a9f 308 Gene3D G3DSA:3.90.1200.10 105 279 1.2E-21 T 12-10-2018 UA74_14850 303f8083c1e39c2cbf81241f5de75a9f 308 Gene3D G3DSA:3.30.200.20 10 99 8.2E-15 T 12-10-2018 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 SUPERFAMILY SSF53223 1 121 1.15E-25 T 12-10-2018 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 9.4E-24 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 277 2.0E-54 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 3.4E-50 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 3.4E-50 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 254 272 3.4E-50 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 3.4E-50 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 3.4E-50 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 3.4E-50 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 Gene3D G3DSA:3.40.50.10860 8 274 6.6E-87 T 12-10-2018 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 SUPERFAMILY SSF51735 125 278 2.39E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 Gene3D G3DSA:3.40.50.720 6 257 6.6E-87 T 12-10-2018 UA74_14965 59134bd5541f395aa33c3ac3e4ac440a 279 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 278 29.906 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UA74_28405 0463632f3a2eef06f256274050837567 353 SUPERFAMILY SSF102114 26 308 1.57E-74 T 12-10-2018 UA74_28405 0463632f3a2eef06f256274050837567 353 SMART SM00729 36 241 1.2E-9 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_28405 0463632f3a2eef06f256274050837567 353 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 27 353 9.7E-115 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28405 0463632f3a2eef06f256274050837567 353 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 27 353 41.32 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28405 0463632f3a2eef06f256274050837567 353 Pfam PF04055 Radical SAM superfamily 42 202 7.3E-30 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_28405 0463632f3a2eef06f256274050837567 353 Gene3D G3DSA:3.20.20.70 24 353 2.0E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_28405 0463632f3a2eef06f256274050837567 353 Pfam PF06463 Molybdenum Cofactor Synthesis C 209 335 4.0E-40 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28405 0463632f3a2eef06f256274050837567 353 Pfam PF13353 4Fe-4S single cluster domain 43 122 2.8E-6 T 12-10-2018 UA74_28405 0463632f3a2eef06f256274050837567 353 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 42 53 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_24550 a3ac8adabec5f37c7e4ebe5e337a3227 365 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 50 343 1.2E-53 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 UA74_24550 a3ac8adabec5f37c7e4ebe5e337a3227 365 SUPERFAMILY SSF53850 49 278 9.96E-35 T 12-10-2018 UA74_24550 a3ac8adabec5f37c7e4ebe5e337a3227 365 Gene3D G3DSA:3.40.190.10 168 341 1.2E-20 T 12-10-2018 UA74_24550 a3ac8adabec5f37c7e4ebe5e337a3227 365 Pfam PF13379 NMT1-like family 47 281 1.2E-27 T 12-10-2018 UA74_24550 a3ac8adabec5f37c7e4ebe5e337a3227 365 Gene3D G3DSA:3.40.190.10 47 167 2.5E-14 T 12-10-2018 UA74_10650 a474ca2da14dc098934515fd611de7f8 242 Pfam PF00005 ABC transporter 24 75 1.2E-5 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_10650 a474ca2da14dc098934515fd611de7f8 242 Gene3D G3DSA:3.40.50.300 4 166 5.9E-13 T 12-10-2018 UA74_10650 a474ca2da14dc098934515fd611de7f8 242 SUPERFAMILY SSF52540 5 166 3.88E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15110 8cd076f92bd037827cc44cdc3733bec4 121 Pfam PF13700 Domain of unknown function (DUF4158) 3 113 5.1E-28 T 12-10-2018 IPR025296 Domain of unknown function DUF4158 UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 414 431 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 447 467 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 319 330 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 393 412 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 244 261 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 367 383 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 249 484 1.1E-55 T 12-10-2018 UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 SUPERFAMILY SSF51735 242 485 4.58E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 Gene3D G3DSA:3.40.50.720 237 485 5.9E-71 T 12-10-2018 UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 243 428 0.0046 T 12-10-2018 UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 319 330 6.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 393 412 6.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_12590 a9cc1f8b451e5563a594c849dc072403 486 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 373 381 6.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_08325 7db171caece55df0f327a6b03074140a 305 Gene3D G3DSA:3.30.479.30 105 239 1.1E-8 T 12-10-2018 UA74_08325 7db171caece55df0f327a6b03074140a 305 SMART SM00244 73 237 1.2E-7 T 12-10-2018 IPR001107 Band 7 domain UA74_08325 7db171caece55df0f327a6b03074140a 305 Pfam PF01145 SPFH domain / Band 7 family 77 249 3.5E-22 T 12-10-2018 IPR001107 Band 7 domain UA74_08325 7db171caece55df0f327a6b03074140a 305 SUPERFAMILY SSF117892 109 239 5.75E-11 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily UA74_09045 eec7f73bd0cbe2850b9fcab8396d72d4 81 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 41 2.8E-9 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_09045 eec7f73bd0cbe2850b9fcab8396d72d4 81 Gene3D G3DSA:3.40.1620.10 1 40 2.8E-11 T 12-10-2018 UA74_09045 eec7f73bd0cbe2850b9fcab8396d72d4 81 SUPERFAMILY SSF143120 5 46 1.22E-9 T 12-10-2018 IPR036165 YefM-like superfamily UA74_09045 eec7f73bd0cbe2850b9fcab8396d72d4 81 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 39 3.7E-6 T 12-10-2018 UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 SUPERFAMILY SSF52172 2 128 5.55E-34 T 12-10-2018 IPR011006 CheY-like superfamily UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 6.8E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 SUPERFAMILY SSF46894 144 215 7.48E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 Pfam PF00072 Response regulator receiver domain 4 118 3.0E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 Gene3D G3DSA:3.40.50.12740 2 215 2.9E-71 T 12-10-2018 UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 SMART SM00421 152 209 1.8E-26 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23280 5b4fdc7fb08443bf52feeca7865a35cd 221 SMART SM00448 2 117 7.1E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_26175 3b01b55b5663196c1bb9541a317eb4cf 204 Gene3D G3DSA:1.10.357.10 61 201 3.4E-32 T 12-10-2018 UA74_26175 3b01b55b5663196c1bb9541a317eb4cf 204 SUPERFAMILY SSF46689 11 93 3.64E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_26175 3b01b55b5663196c1bb9541a317eb4cf 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.5E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_26175 3b01b55b5663196c1bb9541a317eb4cf 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.5E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_26175 3b01b55b5663196c1bb9541a317eb4cf 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_26175 3b01b55b5663196c1bb9541a317eb4cf 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 9.1E-19 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_26175 3b01b55b5663196c1bb9541a317eb4cf 204 SUPERFAMILY SSF48498 91 148 1.92E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_26175 3b01b55b5663196c1bb9541a317eb4cf 204 Gene3D G3DSA:1.10.10.60 17 59 9.1E-22 T 12-10-2018 UA74_03150 d919666299fc23bd2f02e956337c801f 274 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 11 251 7.3E-50 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_03150 d919666299fc23bd2f02e956337c801f 274 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 9 256 32.11 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_03150 d919666299fc23bd2f02e956337c801f 274 Pfam PF01416 tRNA pseudouridine synthase 17 114 1.1E-5 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_03150 d919666299fc23bd2f02e956337c801f 274 Pfam PF01416 tRNA pseudouridine synthase 155 257 8.1E-25 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_03150 d919666299fc23bd2f02e956337c801f 274 Gene3D G3DSA:3.30.70.660 117 255 2.4E-34 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 UA74_03150 d919666299fc23bd2f02e956337c801f 274 SUPERFAMILY SSF55120 9 263 9.93E-72 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_03150 d919666299fc23bd2f02e956337c801f 274 Gene3D G3DSA:3.30.70.580 7 116 3.0E-34 T 12-10-2018 UA74_03150 d919666299fc23bd2f02e956337c801f 274 PIRSF PIRSF001430 8 273 2.3E-70 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_06040 70f3a43413896f00d1f697381b3b1c39 134 SUPERFAMILY SSF46689 8 58 1.03E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_06040 70f3a43413896f00d1f697381b3b1c39 134 SUPERFAMILY SSF46689 60 112 4.48E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_06040 70f3a43413896f00d1f697381b3b1c39 134 SMART SM00342 24 107 2.0E-31 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_06040 70f3a43413896f00d1f697381b3b1c39 134 Gene3D G3DSA:1.10.10.60 4 113 2.2E-31 T 12-10-2018 UA74_06040 70f3a43413896f00d1f697381b3b1c39 134 Pfam PF12833 Helix-turn-helix domain 30 108 1.6E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_06040 70f3a43413896f00d1f697381b3b1c39 134 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 76 91 4.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_06040 70f3a43413896f00d1f697381b3b1c39 134 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 91 107 4.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_03985 8dc7f561d5069695155d82c709aec39c 400 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 44 57 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 UA74_03985 8dc7f561d5069695155d82c709aec39c 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 304 2.6E-85 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_03985 8dc7f561d5069695155d82c709aec39c 400 Gene3D G3DSA:3.40.50.1100 9 308 2.9E-114 T 12-10-2018 UA74_03985 8dc7f561d5069695155d82c709aec39c 400 SUPERFAMILY SSF53686 7 311 1.7E-94 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_03985 8dc7f561d5069695155d82c709aec39c 400 Gene3D G3DSA:3.40.50.1100 52 148 2.9E-114 T 12-10-2018 UA74_03985 8dc7f561d5069695155d82c709aec39c 400 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 23 392 1.9E-128 T 12-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 UA74_12775 22b4a97a71d0a3ab3a882847ebbf3f5c 212 SUPERFAMILY SSF46894 133 185 2.21E-6 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_12775 22b4a97a71d0a3ab3a882847ebbf3f5c 212 Gene3D G3DSA:3.40.50.12740 2 200 2.2E-27 T 12-10-2018 UA74_12775 22b4a97a71d0a3ab3a882847ebbf3f5c 212 Pfam PF00072 Response regulator receiver domain 6 113 7.3E-6 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_12775 22b4a97a71d0a3ab3a882847ebbf3f5c 212 SUPERFAMILY SSF52172 1 126 3.13E-14 T 12-10-2018 IPR011006 CheY-like superfamily UA74_15360 ad29e71f06e554c706c41b3610065df9 209 Gene3D G3DSA:1.10.10.60 2 70 1.9E-27 T 12-10-2018 UA74_15360 ad29e71f06e554c706c41b3610065df9 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 3.2E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15360 ad29e71f06e554c706c41b3610065df9 209 Gene3D G3DSA:1.10.357.10 71 200 1.1E-33 T 12-10-2018 UA74_15360 ad29e71f06e554c706c41b3610065df9 209 SUPERFAMILY SSF48498 83 196 2.31E-29 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_15360 ad29e71f06e554c706c41b3610065df9 209 SUPERFAMILY SSF46689 2 79 1.59E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_09605 2008c2daabe5cd0bb4e71a0c1b184b32 328 PIRSF PIRSF004486 11 324 7.4E-96 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 UA74_09605 2008c2daabe5cd0bb4e71a0c1b184b32 328 SUPERFAMILY SSF81799 127 228 2.09E-32 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 UA74_09605 2008c2daabe5cd0bb4e71a0c1b184b32 328 Gene3D G3DSA:3.40.50.150 16 319 4.9E-92 T 12-10-2018 UA74_09605 2008c2daabe5cd0bb4e71a0c1b184b32 328 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 16 323 36.263 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 UA74_09605 2008c2daabe5cd0bb4e71a0c1b184b32 328 Pfam PF01795 MraW methylase family 14 322 2.4E-106 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 UA74_09605 2008c2daabe5cd0bb4e71a0c1b184b32 328 SUPERFAMILY SSF53335 16 323 1.17E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_09605 2008c2daabe5cd0bb4e71a0c1b184b32 328 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 15 322 7.4E-87 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 UA74_09605 2008c2daabe5cd0bb4e71a0c1b184b32 328 Gene3D G3DSA:1.10.150.170 125 230 4.9E-92 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 UA74_17570 ff4b0cac4e91d778605928e92e0e4636 507 PIRSF PIRSF000331 1 486 1.6E-200 T 12-10-2018 IPR004925 HpaB/PvcC/4-BUDH UA74_17570 ff4b0cac4e91d778605928e92e0e4636 507 PIRSF PIRSF500125 1 502 4.9E-255 T 12-10-2018 IPR024677 4-HPA 3-monooxygenase large component/Pyoverdin chromophore biosynthetic protein UA74_17570 ff4b0cac4e91d778605928e92e0e4636 507 SUPERFAMILY SSF56645 1 267 3.11E-79 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_17570 ff4b0cac4e91d778605928e92e0e4636 507 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 276 474 1.4E-67 T 12-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal UA74_17570 ff4b0cac4e91d778605928e92e0e4636 507 Gene3D G3DSA:1.20.140.10 273 463 3.5E-74 T 12-10-2018 UA74_17570 ff4b0cac4e91d778605928e92e0e4636 507 SUPERFAMILY SSF47203 257 478 2.09E-51 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_17570 ff4b0cac4e91d778605928e92e0e4636 507 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 2 266 1.7E-93 T 12-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal UA74_17570 ff4b0cac4e91d778605928e92e0e4636 507 Gene3D G3DSA:1.10.3140.10 1 138 9.3E-45 T 12-10-2018 UA74_17570 ff4b0cac4e91d778605928e92e0e4636 507 Gene3D G3DSA:2.40.110.10 140 268 3.5E-37 T 12-10-2018 UA74_12710 dd825ed5d0d9652b5985538516a74a9f 178 SUPERFAMILY SSF51182 50 154 1.76E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_12710 dd825ed5d0d9652b5985538516a74a9f 178 Pfam PF07883 Cupin domain 65 120 6.2E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel UA74_12710 dd825ed5d0d9652b5985538516a74a9f 178 Gene3D G3DSA:2.60.120.10 33 168 1.9E-26 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_02985 c5d88844e02fbca46592d8b299cf63a7 84 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 8.7E-21 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02985 c5d88844e02fbca46592d8b299cf63a7 84 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 12-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02985 c5d88844e02fbca46592d8b299cf63a7 84 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 17.434 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02985 c5d88844e02fbca46592d8b299cf63a7 84 Gene3D G3DSA:1.10.287.310 6 69 1.3E-26 T 12-10-2018 UA74_02985 c5d88844e02fbca46592d8b299cf63a7 84 SUPERFAMILY SSF46561 6 67 1.07E-22 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02985 c5d88844e02fbca46592d8b299cf63a7 84 Pfam PF00831 Ribosomal L29 protein 8 64 6.4E-25 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_26310 132aa6b4f27e70a78b28f01e5402dc81 415 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 25 411 8.9E-86 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 UA74_26310 132aa6b4f27e70a78b28f01e5402dc81 415 Gene3D G3DSA:3.40.630.10 34 408 6.2E-118 T 12-10-2018 UA74_26310 132aa6b4f27e70a78b28f01e5402dc81 415 SUPERFAMILY SSF53187 31 415 1.0E-67 T 12-10-2018 UA74_26310 132aa6b4f27e70a78b28f01e5402dc81 415 SUPERFAMILY SSF55031 226 334 3.14E-22 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UA74_26310 132aa6b4f27e70a78b28f01e5402dc81 415 PIRSF PIRSF001235 16 415 9.8E-118 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 UA74_26310 132aa6b4f27e70a78b28f01e5402dc81 415 Pfam PF01546 Peptidase family M20/M25/M40 88 412 3.8E-27 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 UA74_26310 132aa6b4f27e70a78b28f01e5402dc81 415 Gene3D G3DSA:3.30.70.360 224 337 6.2E-118 T 12-10-2018 UA74_04320 4060d3e8829001e1e9c6b655a9c099f6 173 SUPERFAMILY SSF46785 16 153 7.93E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04320 4060d3e8829001e1e9c6b655a9c099f6 173 Gene3D G3DSA:1.10.10.10 10 155 6.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04320 4060d3e8829001e1e9c6b655a9c099f6 173 Pfam PF12802 MarR family 39 101 1.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_04320 4060d3e8829001e1e9c6b655a9c099f6 173 SMART SM00347 34 138 3.4E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_01045 5a3b6c61d61f36c75916a504d5d1dee6 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 334 4.4E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_01045 5a3b6c61d61f36c75916a504d5d1dee6 336 SUPERFAMILY SSF161098 92 319 4.06E-21 T 12-10-2018 IPR035906 MetI-like superfamily UA74_28625 c9ad8d19f5f0d8189298dec1a675366a 259 Gene3D G3DSA:1.10.1740.10 7 95 1.6E-15 T 12-10-2018 UA74_28625 c9ad8d19f5f0d8189298dec1a675366a 259 Pfam PF04542 Sigma-70 region 2 28 95 3.2E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_28625 c9ad8d19f5f0d8189298dec1a675366a 259 SUPERFAMILY SSF88659 114 185 4.49E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_28625 c9ad8d19f5f0d8189298dec1a675366a 259 Gene3D G3DSA:1.10.10.10 100 186 2.5E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28625 c9ad8d19f5f0d8189298dec1a675366a 259 SUPERFAMILY SSF88946 5 109 2.98E-19 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_28625 c9ad8d19f5f0d8189298dec1a675366a 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 182 1.1E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_23770 4d28b536c6af5f13bbc1ba72f6c8e8c3 310 SMART SM01130 2 298 4.8E-61 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_23770 4d28b536c6af5f13bbc1ba72f6c8e8c3 310 PIRSF PIRSF001365 1 302 3.2E-47 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_23770 4d28b536c6af5f13bbc1ba72f6c8e8c3 310 SUPERFAMILY SSF51569 3 296 9.42E-56 T 12-10-2018 UA74_23770 4d28b536c6af5f13bbc1ba72f6c8e8c3 310 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 2 299 40.111 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 UA74_23770 4d28b536c6af5f13bbc1ba72f6c8e8c3 310 Pfam PF00701 Dihydrodipicolinate synthetase family 3 295 2.0E-46 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_23770 4d28b536c6af5f13bbc1ba72f6c8e8c3 310 Gene3D G3DSA:3.20.20.70 2 301 3.0E-76 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_16530 44913df8e10f5f377fb7cf91adeb2ea5 263 SMART SM00824 Thioesterase 38 261 8.7E-4 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_16530 44913df8e10f5f377fb7cf91adeb2ea5 263 Gene3D G3DSA:3.40.50.1820 18 262 2.5E-70 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16530 44913df8e10f5f377fb7cf91adeb2ea5 263 SUPERFAMILY SSF53474 22 259 1.04E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16530 44913df8e10f5f377fb7cf91adeb2ea5 263 Pfam PF00975 Thioesterase domain 36 258 1.3E-56 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_24790 38048c22c4c403aec453b2b21a620bc5 583 Gene3D G3DSA:1.10.287.1060 78 169 1.3E-6 T 12-10-2018 UA74_24790 38048c22c4c403aec453b2b21a620bc5 583 SUPERFAMILY SSF140453 82 170 9.94E-8 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_21415 4644aaa88b9878635aa1ecc70a90c078 358 SUPERFAMILY SSF56601 64 204 2.73E-16 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_21415 4644aaa88b9878635aa1ecc70a90c078 358 Pfam PF13354 Beta-lactamase enzyme family 71 274 1.6E-13 T 12-10-2018 UA74_21415 4644aaa88b9878635aa1ecc70a90c078 358 Gene3D G3DSA:3.40.710.10 51 329 2.0E-28 T 12-10-2018 UA74_01135 2e75369966c5dde800901e4646e705ed 707 SUPERFAMILY SSF82171 110 439 6.67E-19 T 12-10-2018 UA74_01135 2e75369966c5dde800901e4646e705ed 707 Pfam PF00326 Prolyl oligopeptidase family 494 701 1.9E-44 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_01135 2e75369966c5dde800901e4646e705ed 707 Gene3D G3DSA:2.120.10.30 216 452 7.7E-14 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_01135 2e75369966c5dde800901e4646e705ed 707 Gene3D G3DSA:2.120.10.30 92 200 4.3E-6 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_01135 2e75369966c5dde800901e4646e705ed 707 SUPERFAMILY SSF53474 458 700 3.01E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_01135 2e75369966c5dde800901e4646e705ed 707 Gene3D G3DSA:3.40.50.1820 453 703 2.5E-66 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_30000 494675e7cad95f195d5fea125d3f6198 256 Pfam PF01261 Xylose isomerase-like TIM barrel 16 218 7.3E-22 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_30000 494675e7cad95f195d5fea125d3f6198 256 SMART SM00518 2 254 1.8E-44 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 UA74_30000 494675e7cad95f195d5fea125d3f6198 256 SUPERFAMILY SSF51658 1 243 3.01E-51 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_30000 494675e7cad95f195d5fea125d3f6198 256 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 162 169 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 UA74_30000 494675e7cad95f195d5fea125d3f6198 256 Gene3D G3DSA:3.20.20.150 1 254 1.2E-52 T 12-10-2018 UA74_13035 c31371497417d363f269a936a45f4a3a 328 Gene3D G3DSA:3.20.20.100 1 326 1.2E-111 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_13035 c31371497417d363f269a936a45f4a3a 328 SUPERFAMILY SSF51430 1 308 1.01E-97 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_13035 c31371497417d363f269a936a45f4a3a 328 PRINTS PR00069 Aldo-keto reductase signature 43 67 7.7E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_13035 c31371497417d363f269a936a45f4a3a 328 PRINTS PR00069 Aldo-keto reductase signature 140 157 7.7E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_13035 c31371497417d363f269a936a45f4a3a 328 PRINTS PR00069 Aldo-keto reductase signature 109 127 7.7E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_13035 c31371497417d363f269a936a45f4a3a 328 Pfam PF00248 Aldo/keto reductase family 16 306 7.6E-71 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_28665 8d84bcec4211fee72285e583b0af151a 293 Gene3D G3DSA:3.40.50.10330 1 131 1.4E-18 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 UA74_28665 8d84bcec4211fee72285e583b0af151a 293 Gene3D G3DSA:2.60.200.40 136 286 2.1E-14 T 12-10-2018 UA74_28665 8d84bcec4211fee72285e583b0af151a 293 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 126 2.3E-15 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_28665 8d84bcec4211fee72285e583b0af151a 293 SMART SM00046 6 134 0.0014 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UA74_28665 8d84bcec4211fee72285e583b0af151a 293 SUPERFAMILY SSF111331 6 292 1.5E-37 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00473 Galactokinase signature 32 50 2.4E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00473 Galactokinase signature 282 296 2.4E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00473 Galactokinase signature 119 137 2.4E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00473 Galactokinase signature 99 110 2.4E-23 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 128 139 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 TIGRFAM TIGR00131 gal_kin: galactokinase 11 388 2.9E-79 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 SUPERFAMILY SSF55060 223 397 3.96E-43 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 SUPERFAMILY SSF54211 7 218 1.29E-54 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 Pfam PF00288 GHMP kinases N terminal domain 122 196 3.4E-14 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 Gene3D G3DSA:3.30.230.10 26 217 2.2E-116 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 Gene3D G3DSA:3.30.70.890 218 373 2.2E-116 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00959 Mevalonate kinase family signature 178 197 4.6E-40 T 12-10-2018 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00959 Mevalonate kinase family signature 126 148 4.6E-40 T 12-10-2018 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00959 Mevalonate kinase family signature 30 54 4.6E-40 T 12-10-2018 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 PRINTS PR00959 Mevalonate kinase family signature 345 362 4.6E-40 T 12-10-2018 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 Pfam PF08544 GHMP kinases C terminal 303 377 1.0E-12 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 PIRSF PIRSF000530 1 400 3.2E-110 T 12-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 Pfam PF10509 Galactokinase galactose-binding signature 15 62 1.8E-20 T 12-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_08730 366bd2d755c87eb5f255c7785b29a837 404 ProSitePatterns PS00106 Galactokinase signature. 32 43 - T 12-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UA74_18575 f0a4d36b3b81d292391b906f58b4cc5d 182 SMART SM00903 36 182 3.5E-51 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 UA74_18575 f0a4d36b3b81d292391b906f58b4cc5d 182 Gene3D G3DSA:2.30.110.10 16 182 2.0E-50 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_18575 f0a4d36b3b81d292391b906f58b4cc5d 182 SUPERFAMILY SSF50475 30 182 2.5E-46 T 12-10-2018 UA74_18575 f0a4d36b3b81d292391b906f58b4cc5d 182 Pfam PF01613 Flavin reductase like domain 36 182 7.3E-35 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 UA74_08980 6610d4a9000ce2104ffcbc2412429d47 92 Pfam PF10939 Protein of unknown function (DUF2631) 9 72 1.1E-28 T 12-10-2018 IPR024341 Protein of unknown function DUF2631 UA74_08980 6610d4a9000ce2104ffcbc2412429d47 92 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 13 87 4.0E-10 T 12-10-2018 IPR024341 Protein of unknown function DUF2631 UA74_26215 31d3f971437f32dea4619eef535a136f 389 SUPERFAMILY SSF103473 20 379 1.57E-42 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_26215 31d3f971437f32dea4619eef535a136f 389 Pfam PF07690 Major Facilitator Superfamily 27 352 1.1E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_26215 31d3f971437f32dea4619eef535a136f 389 Gene3D G3DSA:1.20.1250.20 18 382 1.2E-39 T 12-10-2018 UA74_16330 44978c1592b942616f447f18897b8147 422 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 268 376 6.7E-10 T 12-10-2018 IPR024534 Domain of unknown function DUF2220 UA74_16330 44978c1592b942616f447f18897b8147 422 Pfam PF11796 Protein of unknown function N-terminus (DUF3323) 39 111 7.8E-7 T 12-10-2018 IPR024466 Conserved hypothetical protein CHP02679, N terminus UA74_16330 44978c1592b942616f447f18897b8147 422 SUPERFAMILY SSF56726 231 335 4.18E-5 T 12-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 9.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 9.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 9.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 9.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 Pfam PF00106 short chain dehydrogenase 7 211 6.7E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 Gene3D G3DSA:3.40.50.720 1 277 1.1E-61 T 12-10-2018 UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 1.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29875 f54a10b888477ab2bbc9e45bea138b52 292 SUPERFAMILY SSF51735 6 234 2.04E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14060 c55dff0447c5ec611cba76971f2ce29b 423 SUPERFAMILY SSF55874 333 420 9.31E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_14060 c55dff0447c5ec611cba76971f2ce29b 423 Gene3D G3DSA:3.30.565.10 301 421 1.3E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_14060 c55dff0447c5ec611cba76971f2ce29b 423 Pfam PF07730 Histidine kinase 231 297 8.9E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_14060 c55dff0447c5ec611cba76971f2ce29b 423 Pfam PF13796 Putative sensor 29 201 1.0E-10 T 12-10-2018 IPR025828 Putative sensor domain UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 Gene3D G3DSA:3.50.50.60 48 410 4.1E-130 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 424 548 3.7E-34 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 52 69 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 Gene3D G3DSA:1.10.8.870 435 577 2.2E-33 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 Gene3D G3DSA:3.30.9.10 126 368 4.1E-130 T 12-10-2018 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 396 406 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 76 88 9.0E-34 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 391 403 9.0E-34 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 122 134 9.0E-34 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 47 59 9.0E-34 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 60 70 9.0E-34 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 361 367 9.0E-34 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 Pfam PF01266 FAD dependent oxidoreductase 48 396 3.9E-53 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_26970 0e92ce33b0b1f585078feae33c3554bd 593 SUPERFAMILY SSF51905 47 371 6.18E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 Gene3D G3DSA:3.30.70.2740 382 458 2.6E-8 T 12-10-2018 UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 SUPERFAMILY SSF55103 260 500 4.91E-51 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 SUPERFAMILY SSF56176 26 256 2.09E-49 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 Pfam PF13183 4Fe-4S dicluster domain 535 615 1.2E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 SUPERFAMILY SSF46548 531 620 3.03E-8 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 Pfam PF02754 Cysteine-rich domain 816 891 0.045 T 12-10-2018 IPR004017 Cysteine-rich domain UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 Pfam PF01565 FAD binding domain 47 183 1.4E-39 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 Gene3D G3DSA:3.30.465.40 27 264 8.8E-46 T 12-10-2018 UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 601 612 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_19790 18c9cbd444129293defd9375e77a39d1 1046 Pfam PF02913 FAD linked oxidases, C-terminal domain 260 496 1.4E-46 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 UA74_24130 05ea196830066b19d22677bffe46f767 273 Pfam PF03073 TspO/MBR family 29 176 3.9E-5 T 12-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 UA74_14860 cb35562f54ca6b2e2a1cacb109bfad98 607 Pfam PF00664 ABC transporter transmembrane region 33 304 7.8E-27 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_14860 cb35562f54ca6b2e2a1cacb109bfad98 607 Pfam PF00005 ABC transporter 365 511 2.6E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_14860 cb35562f54ca6b2e2a1cacb109bfad98 607 SMART SM00382 372 557 4.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_14860 cb35562f54ca6b2e2a1cacb109bfad98 607 Gene3D G3DSA:1.20.1560.10 10 330 1.1E-54 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_14860 cb35562f54ca6b2e2a1cacb109bfad98 607 SUPERFAMILY SSF52540 341 581 5.04E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14860 cb35562f54ca6b2e2a1cacb109bfad98 607 SUPERFAMILY SSF90123 22 327 7.06E-56 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_14860 cb35562f54ca6b2e2a1cacb109bfad98 607 Gene3D G3DSA:3.40.50.300 340 591 2.7E-68 T 12-10-2018 UA74_29795 83949196a0233e2129837dc6563bdd56 476 SUPERFAMILY SSF103473 26 475 2.35E-66 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_29795 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 285 295 2.0E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_29795 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 381 402 2.0E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_29795 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 38 48 2.0E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_29795 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 121 140 2.0E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_29795 83949196a0233e2129837dc6563bdd56 476 PRINTS PR00171 Sugar transporter signature 404 416 2.0E-23 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_29795 83949196a0233e2129837dc6563bdd56 476 ProSitePatterns PS00216 Sugar transport proteins signature 1. 329 346 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_29795 83949196a0233e2129837dc6563bdd56 476 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 22 475 9.3E-105 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UA74_29795 83949196a0233e2129837dc6563bdd56 476 Pfam PF00083 Sugar (and other) transporter 34 475 1.1E-101 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UA74_29795 83949196a0233e2129837dc6563bdd56 476 Gene3D G3DSA:1.20.1250.20 22 476 9.5E-119 T 12-10-2018 UA74_05645 72a1a4cff8ca1d6986fb260bf95e76f7 109 Pfam PF06013 Proteins of 100 residues with WXG 5 88 2.0E-9 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like UA74_05645 72a1a4cff8ca1d6986fb260bf95e76f7 109 Gene3D G3DSA:1.10.287.1060 3 101 3.2E-14 T 12-10-2018 UA74_05645 72a1a4cff8ca1d6986fb260bf95e76f7 109 SUPERFAMILY SSF140453 5 100 6.15E-10 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_22575 4de6d8f0d07a80659524f43b3daa73e3 157 SUPERFAMILY SSF69118 13 152 4.06E-39 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_22575 4de6d8f0d07a80659524f43b3daa73e3 157 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 80 2.3E-19 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UA74_22575 4de6d8f0d07a80659524f43b3daa73e3 157 Gene3D G3DSA:1.20.1290.10 1 150 5.2E-44 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_22575 4de6d8f0d07a80659524f43b3daa73e3 157 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 95 3.6E-20 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UA74_23910 386a31148d4bee6d972814682122e860 222 SUPERFAMILY SSF140453 57 122 1.96E-6 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_23910 386a31148d4bee6d972814682122e860 222 Gene3D G3DSA:1.10.287.1060 41 127 5.6E-6 T 12-10-2018 UA74_15455 26ae7e1e936d594f719230e051300ec9 326 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_15455 26ae7e1e936d594f719230e051300ec9 326 Gene3D G3DSA:3.40.50.300 4 245 2.2E-67 T 12-10-2018 UA74_15455 26ae7e1e936d594f719230e051300ec9 326 Pfam PF00005 ABC transporter 24 166 2.6E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_15455 26ae7e1e936d594f719230e051300ec9 326 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 16 311 6.1E-97 T 12-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 UA74_15455 26ae7e1e936d594f719230e051300ec9 326 SUPERFAMILY SSF52540 7 230 1.25E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15455 26ae7e1e936d594f719230e051300ec9 326 SMART SM00382 32 217 8.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_05530 503e871c0f7bf7d05c82dfe75cb1275c 210 Gene3D G3DSA:3.40.50.150 40 206 5.2E-33 T 12-10-2018 UA74_05530 503e871c0f7bf7d05c82dfe75cb1275c 210 SUPERFAMILY SSF53335 15 197 1.66E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_05530 503e871c0f7bf7d05c82dfe75cb1275c 210 Pfam PF08241 Methyltransferase domain 50 143 9.8E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_04485 4748b96c1eb1e981bc578433c6ec2ba8 151 Gene3D G3DSA:3.30.530.20 6 148 8.6E-12 T 12-10-2018 IPR023393 START-like domain superfamily UA74_04485 4748b96c1eb1e981bc578433c6ec2ba8 151 SUPERFAMILY SSF55961 6 146 1.15E-17 T 12-10-2018 UA74_04485 4748b96c1eb1e981bc578433c6ec2ba8 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 7.9E-9 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase UA74_15520 41aa3f5537f57046b80ec1991d5a00db 414 Pfam PF00589 Phage integrase family 332 401 6.9E-7 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_15520 41aa3f5537f57046b80ec1991d5a00db 414 SUPERFAMILY SSF56349 168 411 1.35E-30 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_15520 41aa3f5537f57046b80ec1991d5a00db 414 SUPERFAMILY SSF47823 58 164 1.35E-25 T 12-10-2018 UA74_15520 41aa3f5537f57046b80ec1991d5a00db 414 Gene3D G3DSA:1.10.150.130 50 166 1.2E-27 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_00030 49bf493e1f719816b255838d5d762d68 655 Pfam PF00204 DNA gyrase B 236 405 4.4E-62 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_00030 49bf493e1f719816b255838d5d762d68 655 Gene3D G3DSA:3.30.230.10 235 407 9.2E-74 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_00030 49bf493e1f719816b255838d5d762d68 655 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 655 5.1E-290 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 175 5.4E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_00030 49bf493e1f719816b255838d5d762d68 655 SUPERFAMILY SSF54211 236 406 1.02E-58 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_00030 49bf493e1f719816b255838d5d762d68 655 SMART SM00387 33 176 2.0E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 539 551 3.3E-70 T 12-10-2018 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 501 517 3.3E-70 T 12-10-2018 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 283 296 3.3E-70 T 12-10-2018 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 519 536 3.3E-70 T 12-10-2018 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 115 129 3.3E-70 T 12-10-2018 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 587 603 3.3E-70 T 12-10-2018 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 72 85 3.3E-70 T 12-10-2018 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 435 449 3.3E-70 T 12-10-2018 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR00418 DNA topoisomerase II family signature 37 52 3.3E-70 T 12-10-2018 UA74_00030 49bf493e1f719816b255838d5d762d68 655 SMART SM00433 37 648 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_00030 49bf493e1f719816b255838d5d762d68 655 Gene3D G3DSA:3.40.50.670 413 655 2.7E-98 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_00030 49bf493e1f719816b255838d5d762d68 655 Pfam PF01751 Toprim domain 434 544 4.5E-16 T 12-10-2018 IPR006171 TOPRIM domain UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 235 257 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 375 389 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 196 209 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 389 409 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 8 18 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 485 494 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 181 196 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 327 343 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 624 640 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 PRINTS PR01159 DNA gyrase subunit B signature 608 620 3.8E-69 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 SUPERFAMILY SSF56719 409 650 7.06E-83 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UA74_00030 49bf493e1f719816b255838d5d762d68 655 Gene3D G3DSA:3.30.565.10 4 220 9.4E-83 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_00030 49bf493e1f719816b255838d5d762d68 655 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 587 643 1.4E-26 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 SUPERFAMILY SSF55874 7 210 4.24E-68 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_00030 49bf493e1f719816b255838d5d762d68 655 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 655 91.558 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UA74_00030 49bf493e1f719816b255838d5d762d68 655 ProSitePatterns PS00177 DNA topoisomerase II signature. 437 445 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_00745 c6bfe045eda8c29aacf60e4686c6caa1 143 Pfam PF12802 MarR family 27 87 3.8E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00745 c6bfe045eda8c29aacf60e4686c6caa1 143 SMART SM00347 21 124 5.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00745 c6bfe045eda8c29aacf60e4686c6caa1 143 Gene3D G3DSA:1.10.10.10 1 142 1.6E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_00745 c6bfe045eda8c29aacf60e4686c6caa1 143 SUPERFAMILY SSF46785 4 139 3.24E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_00745 c6bfe045eda8c29aacf60e4686c6caa1 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 4.2E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00745 c6bfe045eda8c29aacf60e4686c6caa1 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 4.2E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00745 c6bfe045eda8c29aacf60e4686c6caa1 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 4.2E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00745 c6bfe045eda8c29aacf60e4686c6caa1 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 4.2E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_12220 7e6d0d45c9a898b48051021b8b430824 105 Gene3D G3DSA:1.10.8.50 1 105 1.1E-43 T 12-10-2018 UA74_12220 7e6d0d45c9a898b48051021b8b430824 105 PIRSF PIRSF002134 37 105 2.3E-5 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_12220 7e6d0d45c9a898b48051021b8b430824 105 SUPERFAMILY SSF46946 54 103 5.1E-6 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UA74_03685 344d995ac828eb8694f5f66efff5b8ee 340 Gene3D G3DSA:1.10.287.1080 111 237 6.7E-41 T 12-10-2018 UA74_03685 344d995ac828eb8694f5f66efff5b8ee 340 SUPERFAMILY SSF101386 116 213 1.8E-22 T 12-10-2018 UA74_03685 344d995ac828eb8694f5f66efff5b8ee 340 TIGRFAM TIGR00444 mazG: MazG family protein 119 262 5.9E-44 T 12-10-2018 IPR011551 NTP pyrophosphohydrolase MazG UA74_03685 344d995ac828eb8694f5f66efff5b8ee 340 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 135 210 1.5E-24 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core UA74_03685 344d995ac828eb8694f5f66efff5b8ee 340 Gene3D G3DSA:1.10.287.1080 268 338 1.4E-8 T 12-10-2018 UA74_27545 8aa2d31c269304220cd2f4262cb0efa4 219 Pfam PF08044 Domain of unknown function (DUF1707) 19 71 7.7E-21 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 UA74_21230 cddda01b1709366cad49d630e30db187 320 Pfam PF01551 Peptidase family M23 214 308 1.7E-32 T 12-10-2018 IPR016047 Peptidase M23 UA74_21230 cddda01b1709366cad49d630e30db187 320 Gene3D G3DSA:2.70.70.10 161 315 2.1E-46 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_21230 cddda01b1709366cad49d630e30db187 320 SUPERFAMILY SSF51261 153 312 1.62E-51 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 305 76.79 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 Gene3D G3DSA:3.40.50.1370 9 300 3.8E-119 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 302 3.1E-53 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 304 1.1E-115 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 Gene3D G3DSA:3.40.50.1370 131 291 3.8E-119 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 141 1.5E-46 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 5.3E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 5.3E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 5.3E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 5.3E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 SUPERFAMILY SSF53671 2 305 2.23E-98 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 46 53 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 221 231 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 283 294 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UA74_21615 9e8e0c8c93a393216b2316aa177845fe 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 4.5E-30 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UA74_25325 0dc069d81896f38c603960606e677505 306 Gene3D G3DSA:1.10.260.40 30 100 1.4E-7 T 12-10-2018 UA74_25325 0dc069d81896f38c603960606e677505 306 SMART SM00530 6 83 4.5E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_25325 0dc069d81896f38c603960606e677505 306 Gene3D G3DSA:3.30.450.180 109 285 5.7E-12 T 12-10-2018 UA74_25325 0dc069d81896f38c603960606e677505 306 SUPERFAMILY SSF47413 32 81 1.16E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_25325 0dc069d81896f38c603960606e677505 306 Pfam PF13560 Helix-turn-helix domain 33 86 4.2E-15 T 12-10-2018 UA74_09775 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 7.6E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09775 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 7.6E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09775 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 7.6E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09775 b479f039ec9383fea165c3510930bbe0 249 Gene3D G3DSA:3.40.50.720 2 246 3.0E-59 T 12-10-2018 UA74_09775 b479f039ec9383fea165c3510930bbe0 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_09775 b479f039ec9383fea165c3510930bbe0 249 SUPERFAMILY SSF51735 3 246 5.76E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_09775 b479f039ec9383fea165c3510930bbe0 249 Pfam PF00106 short chain dehydrogenase 6 210 4.8E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09775 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 4.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09775 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 4.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09775 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09775 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 4.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_09775 b479f039ec9383fea165c3510930bbe0 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_03540 67c934b934fb900f4724f05f20c2a4f7 311 Gene3D G3DSA:3.10.450.50 166 299 4.3E-9 T 12-10-2018 UA74_03540 67c934b934fb900f4724f05f20c2a4f7 311 Pfam PF08281 Sigma-70, region 4 108 159 1.2E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_03540 67c934b934fb900f4724f05f20c2a4f7 311 SUPERFAMILY SSF88946 6 90 4.32E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_03540 67c934b934fb900f4724f05f20c2a4f7 311 Gene3D G3DSA:1.10.1740.10 2 76 1.1E-10 T 12-10-2018 UA74_03540 67c934b934fb900f4724f05f20c2a4f7 311 SUPERFAMILY SSF54427 171 291 1.5E-10 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_03540 67c934b934fb900f4724f05f20c2a4f7 311 Gene3D G3DSA:1.10.10.10 89 165 1.8E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_03540 67c934b934fb900f4724f05f20c2a4f7 311 SUPERFAMILY SSF88659 105 160 6.54E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_03540 67c934b934fb900f4724f05f20c2a4f7 311 Pfam PF04542 Sigma-70 region 2 9 72 3.0E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_03540 67c934b934fb900f4724f05f20c2a4f7 311 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 160 3.3E-16 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 36 199 2.3E-30 T 12-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 233 245 - T 12-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 Gene3D G3DSA:1.10.1040.10 297 505 6.7E-61 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 Gene3D G3DSA:3.40.50.720 15 296 1.3E-85 T 12-10-2018 UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 PRINTS PR00084 Mannitol dehydrogenase signature 263 278 1.8E-12 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 PRINTS PR00084 Mannitol dehydrogenase signature 37 47 1.8E-12 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 PRINTS PR00084 Mannitol dehydrogenase signature 190 203 1.8E-12 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 SUPERFAMILY SSF48179 298 502 7.48E-50 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 SUPERFAMILY SSF51735 21 296 4.33E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22170 fcee78633cab3aae36e1cfbe7917082e 506 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 232 461 1.3E-65 T 12-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 UA74_29920 7a7a351eec5fea8258db044adf2646d0 362 Pfam PF02779 Transketolase, pyrimidine binding domain 41 216 3.0E-43 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_29920 7a7a351eec5fea8258db044adf2646d0 362 Gene3D G3DSA:3.40.50.970 38 236 1.6E-76 T 12-10-2018 UA74_29920 7a7a351eec5fea8258db044adf2646d0 362 SMART SM00861 42 217 4.5E-68 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_29920 7a7a351eec5fea8258db044adf2646d0 362 SUPERFAMILY SSF52922 229 361 9.29E-34 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_29920 7a7a351eec5fea8258db044adf2646d0 362 Pfam PF02780 Transketolase, C-terminal domain 234 352 3.0E-32 T 12-10-2018 IPR033248 Transketolase, C-terminal domain UA74_29920 7a7a351eec5fea8258db044adf2646d0 362 SUPERFAMILY SSF52518 41 220 1.87E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_29920 7a7a351eec5fea8258db044adf2646d0 362 Gene3D G3DSA:3.40.50.920 237 358 2.4E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_11845 62ea468670dd466d6a472dacef84955a 426 SMART SM00812 2 364 6.8E-112 T 12-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 UA74_11845 62ea468670dd466d6a472dacef84955a 426 Gene3D G3DSA:2.60.40.1180 326 386 7.5E-109 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_11845 62ea468670dd466d6a472dacef84955a 426 PRINTS PR00741 Glycosyl hydrolase family 29 signature 119 138 2.3E-21 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 UA74_11845 62ea468670dd466d6a472dacef84955a 426 PRINTS PR00741 Glycosyl hydrolase family 29 signature 308 330 2.3E-21 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 UA74_11845 62ea468670dd466d6a472dacef84955a 426 PRINTS PR00741 Glycosyl hydrolase family 29 signature 275 296 2.3E-21 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 UA74_11845 62ea468670dd466d6a472dacef84955a 426 PRINTS PR00741 Glycosyl hydrolase family 29 signature 74 90 2.3E-21 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 UA74_11845 62ea468670dd466d6a472dacef84955a 426 Gene3D G3DSA:3.20.20.80 11 325 7.5E-109 T 12-10-2018 UA74_11845 62ea468670dd466d6a472dacef84955a 426 PIRSF PIRSF001092 2 389 7.6E-111 T 12-10-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 UA74_11845 62ea468670dd466d6a472dacef84955a 426 Pfam PF01120 Alpha-L-fucosidase 8 321 3.6E-87 T 12-10-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 UA74_11845 62ea468670dd466d6a472dacef84955a 426 SUPERFAMILY SSF51445 4 325 8.43E-95 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_25485 644b54b2133d9412636d6983305ad823 460 TIGRFAM TIGR00836 amt: ammonium transporter 5 413 2.5E-139 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 UA74_25485 644b54b2133d9412636d6983305ad823 460 Gene3D G3DSA:1.10.3430.10 1 420 2.6E-141 T 12-10-2018 IPR029020 Ammonium/urea transporter UA74_25485 644b54b2133d9412636d6983305ad823 460 Pfam PF00909 Ammonium Transporter Family 7 413 4.4E-126 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 UA74_25485 644b54b2133d9412636d6983305ad823 460 SUPERFAMILY SSF111352 2 394 1.15E-120 T 12-10-2018 UA74_25485 644b54b2133d9412636d6983305ad823 460 ProSitePatterns PS01219 Ammonium transporters signature. 169 194 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 UA74_27210 2b3df60b2d8865cac92390b51c428570 632 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 25 48 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_27210 2b3df60b2d8865cac92390b51c428570 632 SMART SM00220 19 278 1.3E-58 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_27210 2b3df60b2d8865cac92390b51c428570 632 Gene3D G3DSA:3.30.200.20 10 102 1.7E-27 T 12-10-2018 UA74_27210 2b3df60b2d8865cac92390b51c428570 632 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 142 154 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_27210 2b3df60b2d8865cac92390b51c428570 632 SUPERFAMILY SSF56112 11 276 7.01E-67 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_27210 2b3df60b2d8865cac92390b51c428570 632 Pfam PF00069 Protein kinase domain 19 224 3.2E-45 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_27210 2b3df60b2d8865cac92390b51c428570 632 Gene3D G3DSA:1.10.510.10 105 297 4.5E-40 T 12-10-2018 UA74_10870 3bae143c78c89372669e05e827af92cc 528 SUPERFAMILY SSF49503 51 221 1.31E-24 T 12-10-2018 IPR008972 Cupredoxin UA74_10870 3bae143c78c89372669e05e827af92cc 528 Pfam PF07732 Multicopper oxidase 178 219 3.9E-4 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_10870 3bae143c78c89372669e05e827af92cc 528 Pfam PF07732 Multicopper oxidase 87 143 3.2E-10 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_10870 3bae143c78c89372669e05e827af92cc 528 Pfam PF07731 Multicopper oxidase 419 527 1.6E-19 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_10870 3bae143c78c89372669e05e827af92cc 528 Gene3D G3DSA:2.60.40.420 394 528 1.7E-39 T 12-10-2018 IPR008972 Cupredoxin UA74_10870 3bae143c78c89372669e05e827af92cc 528 Gene3D G3DSA:2.60.40.420 217 393 3.3E-52 T 12-10-2018 IPR008972 Cupredoxin UA74_10870 3bae143c78c89372669e05e827af92cc 528 SUPERFAMILY SSF49503 409 527 7.08E-27 T 12-10-2018 IPR008972 Cupredoxin UA74_10870 3bae143c78c89372669e05e827af92cc 528 Gene3D G3DSA:2.60.40.420 51 216 6.0E-37 T 12-10-2018 IPR008972 Cupredoxin UA74_10870 3bae143c78c89372669e05e827af92cc 528 ProSitePatterns PS00080 Multicopper oxidases signature 2. 510 521 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 UA74_10870 3bae143c78c89372669e05e827af92cc 528 SUPERFAMILY SSF49503 223 359 2.9E-22 T 12-10-2018 IPR008972 Cupredoxin UA74_21015 c6d98c17a033a01931b338586e87d4f2 437 Gene3D G3DSA:3.40.50.2000 16 185 2.1E-97 T 12-10-2018 UA74_21015 c6d98c17a033a01931b338586e87d4f2 437 Pfam PF00534 Glycosyl transferases group 1 224 404 4.0E-25 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_21015 c6d98c17a033a01931b338586e87d4f2 437 Gene3D G3DSA:3.40.50.2000 186 410 2.1E-97 T 12-10-2018 UA74_21015 c6d98c17a033a01931b338586e87d4f2 437 SUPERFAMILY SSF53756 18 420 3.95E-47 T 12-10-2018 UA74_11700 1102272a6ddebe356474204fa79e21f3 392 Pfam PF00108 Thiolase, N-terminal domain 5 262 2.0E-60 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UA74_11700 1102272a6ddebe356474204fa79e21f3 392 Gene3D G3DSA:3.40.47.10 127 386 1.5E-129 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11700 1102272a6ddebe356474204fa79e21f3 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 UA74_11700 1102272a6ddebe356474204fa79e21f3 392 SUPERFAMILY SSF53901 270 391 2.14E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11700 1102272a6ddebe356474204fa79e21f3 392 Pfam PF02803 Thiolase, C-terminal domain 270 391 8.7E-39 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UA74_11700 1102272a6ddebe356474204fa79e21f3 392 SUPERFAMILY SSF53901 1 266 1.45E-67 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11700 1102272a6ddebe356474204fa79e21f3 392 Gene3D G3DSA:3.40.47.10 6 275 1.5E-129 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11700 1102272a6ddebe356474204fa79e21f3 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 8.4E-130 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_11700 1102272a6ddebe356474204fa79e21f3 392 PIRSF PIRSF000429 1 392 8.3E-114 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:1.10.10.1790 490 535 8.8E-24 T 12-10-2018 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:3.30.70.2100 577 644 1.6E-30 T 12-10-2018 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 SUPERFAMILY SSF51905 105 714 1.36E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:1.10.1200.190 176 383 8.0E-148 T 12-10-2018 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 SUPERFAMILY SSF54373 572 661 2.03E-18 T 12-10-2018 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Pfam PF01593 Flavin containing amine oxidoreductase 575 713 3.0E-18 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Pfam PF01593 Flavin containing amine oxidoreductase 367 504 4.8E-11 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Pfam PF01593 Flavin containing amine oxidoreductase 115 198 2.0E-16 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:3.30.160.490 245 281 8.0E-148 T 12-10-2018 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:1.10.10.1620 669 716 7.2E-20 T 12-10-2018 UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:3.50.50.60 105 409 8.0E-148 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_08520 717dba991f0317f2f3743db3afa7afbb 719 Gene3D G3DSA:1.10.405.10 282 372 8.0E-148 T 12-10-2018 UA74_11520 a72a7389c0f0eba6b92ec143b44e3723 323 Pfam PF07584 Aerotolerance regulator N-terminal 9 81 3.0E-8 T 12-10-2018 IPR024163 Aerotolerance regulator, N-terminal UA74_11520 a72a7389c0f0eba6b92ec143b44e3723 323 SUPERFAMILY SSF53300 88 285 5.29E-29 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_11520 a72a7389c0f0eba6b92ec143b44e3723 323 Gene3D G3DSA:3.40.50.410 82 287 5.4E-43 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_11520 a72a7389c0f0eba6b92ec143b44e3723 323 Pfam PF13519 von Willebrand factor type A domain 94 207 1.7E-19 T 12-10-2018 IPR002035 von Willebrand factor, type A UA74_11520 a72a7389c0f0eba6b92ec143b44e3723 323 SMART SM00327 91 288 3.6E-23 T 12-10-2018 IPR002035 von Willebrand factor, type A UA74_18165 8b59e1f9cb9cdeffe139ef7066dc8110 353 Gene3D G3DSA:3.40.50.2300 81 321 2.6E-36 T 12-10-2018 UA74_18165 8b59e1f9cb9cdeffe139ef7066dc8110 353 Pfam PF13377 Periplasmic binding protein-like domain 186 346 8.0E-32 T 12-10-2018 UA74_18165 8b59e1f9cb9cdeffe139ef7066dc8110 353 SUPERFAMILY SSF47413 25 85 1.13E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_18165 8b59e1f9cb9cdeffe139ef7066dc8110 353 SMART SM00354 25 97 1.4E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_18165 8b59e1f9cb9cdeffe139ef7066dc8110 353 Pfam PF00356 Bacterial regulatory proteins, lacI family 29 73 5.1E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_18165 8b59e1f9cb9cdeffe139ef7066dc8110 353 Gene3D G3DSA:1.10.260.40 18 80 3.4E-20 T 12-10-2018 UA74_18165 8b59e1f9cb9cdeffe139ef7066dc8110 353 SUPERFAMILY SSF53822 166 349 4.71E-33 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_18165 8b59e1f9cb9cdeffe139ef7066dc8110 353 Gene3D G3DSA:3.40.50.2300 178 306 2.6E-36 T 12-10-2018 UA74_15865 ddc2bfba1afbafd5184bed24e218635c 876 SUPERFAMILY SSF52540 11 155 2.81E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15865 ddc2bfba1afbafd5184bed24e218635c 876 Gene3D G3DSA:3.40.50.300 18 174 5.7E-12 T 12-10-2018 UA74_15865 ddc2bfba1afbafd5184bed24e218635c 876 Pfam PF04851 Type III restriction enzyme, res subunit 23 150 4.1E-7 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_15865 ddc2bfba1afbafd5184bed24e218635c 876 Gene3D G3DSA:3.40.50.300 411 506 1.1E-5 T 12-10-2018 UA74_01430 42b9187d28d3be65ea1118b487af7151 780 Pfam PF00271 Helicase conserved C-terminal domain 291 399 5.8E-11 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_01430 42b9187d28d3be65ea1118b487af7151 780 SUPERFAMILY SSF52540 72 410 3.2E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01430 42b9187d28d3be65ea1118b487af7151 780 Gene3D G3DSA:3.40.50.300 280 423 2.2E-19 T 12-10-2018 UA74_01430 42b9187d28d3be65ea1118b487af7151 780 Gene3D G3DSA:3.40.50.300 44 246 6.4E-38 T 12-10-2018 UA74_01430 42b9187d28d3be65ea1118b487af7151 780 SMART SM00490 318 399 1.4E-13 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_01430 42b9187d28d3be65ea1118b487af7151 780 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 25 771 0.0 T 12-10-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria UA74_01430 42b9187d28d3be65ea1118b487af7151 780 Pfam PF00270 DEAD/DEAH box helicase 64 229 1.9E-20 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_01430 42b9187d28d3be65ea1118b487af7151 780 Pfam PF09369 Domain of unknown function (DUF1998) 666 745 3.9E-17 T 12-10-2018 IPR018973 DEAD/DEAH-box helicase, putative UA74_01430 42b9187d28d3be65ea1118b487af7151 780 SMART SM00487 57 259 4.7E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_18090 d98f8fa77fbf1a69d1fa788d4caf4ca5 286 Pfam PF03537 Glycoside-hydrolase family GH114 45 272 4.7E-38 T 12-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain UA74_18090 d98f8fa77fbf1a69d1fa788d4caf4ca5 286 SUPERFAMILY SSF51445 57 256 2.74E-16 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_19545 9b3e5e82331fac0ee0a94f9b5509b152 386 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 50 144 5.0E-12 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_19545 9b3e5e82331fac0ee0a94f9b5509b152 386 Gene3D G3DSA:3.20.20.120 146 365 1.2E-139 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_19545 9b3e5e82331fac0ee0a94f9b5509b152 386 SUPERFAMILY SSF54826 1 149 4.57E-21 T 12-10-2018 UA74_19545 9b3e5e82331fac0ee0a94f9b5509b152 386 SUPERFAMILY SSF51604 144 383 1.18E-60 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_19545 9b3e5e82331fac0ee0a94f9b5509b152 386 Pfam PF13378 Enolase C-terminal domain-like 167 378 2.0E-53 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_19545 9b3e5e82331fac0ee0a94f9b5509b152 386 Gene3D G3DSA:3.30.390.10 6 375 1.2E-139 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_19545 9b3e5e82331fac0ee0a94f9b5509b152 386 SMART SM00922 163 258 2.0E-15 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_18680 4698f8290194c80e24d4d0d3dc310876 341 SUPERFAMILY SSF48576 18 292 2.88E-41 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_18680 4698f8290194c80e24d4d0d3dc310876 341 Gene3D G3DSA:1.10.600.10 7 270 7.5E-50 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_18680 4698f8290194c80e24d4d0d3dc310876 341 Pfam PF00494 Squalene/phytoene synthase 32 279 1.2E-33 T 12-10-2018 UA74_24950 ae6573e964fc4f84ed2f495141882f9d 642 SUPERFAMILY SSF56235 2 232 3.69E-53 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_24950 ae6573e964fc4f84ed2f495141882f9d 642 Pfam PF13537 Glutamine amidotransferase domain 50 172 8.0E-38 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain UA74_24950 ae6573e964fc4f84ed2f495141882f9d 642 PIRSF PIRSF001589 1 634 3.0E-172 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UA74_24950 ae6573e964fc4f84ed2f495141882f9d 642 Pfam PF00733 Asparagine synthase 253 621 1.4E-101 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 UA74_24950 ae6573e964fc4f84ed2f495141882f9d 642 SUPERFAMILY SSF52402 249 617 4.19E-82 T 12-10-2018 UA74_24950 ae6573e964fc4f84ed2f495141882f9d 642 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 559 2.9E-142 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UA74_24950 ae6573e964fc4f84ed2f495141882f9d 642 Gene3D G3DSA:3.60.20.10 4 192 3.9E-55 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_12125 50273662ac04f83293503ec2f821686a 395 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_12125 50273662ac04f83293503ec2f821686a 395 SUPERFAMILY SSF103263 2 392 1.16E-129 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_12125 50273662ac04f83293503ec2f821686a 395 TIGRFAM TIGR00033 aroC: chorismate synthase 2 374 2.3E-119 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_12125 50273662ac04f83293503ec2f821686a 395 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_12125 50273662ac04f83293503ec2f821686a 395 Hamap MF_00300 Chorismate synthase [aroC]. 2 376 33.57 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_12125 50273662ac04f83293503ec2f821686a 395 PIRSF PIRSF001456 1 386 1.7E-120 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_12125 50273662ac04f83293503ec2f821686a 395 Gene3D G3DSA:3.60.150.10 1 395 2.2E-152 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_12125 50273662ac04f83293503ec2f821686a 395 Pfam PF01264 Chorismate synthase 2 369 1.3E-112 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UA74_22850 f0fb0b9a9bbb25acbcbbb5fcef518a1f 197 Pfam PF11706 CGNR zinc finger 147 187 1.4E-10 T 12-10-2018 IPR021005 Zinc finger, CGNR UA74_22850 f0fb0b9a9bbb25acbcbbb5fcef518a1f 197 Gene3D G3DSA:1.10.3300.10 6 188 4.4E-21 T 12-10-2018 IPR023286 ABATE domain superfamily UA74_22850 f0fb0b9a9bbb25acbcbbb5fcef518a1f 197 Pfam PF07336 Putative stress-induced transcription regulator 1 143 1.8E-13 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator UA74_22850 f0fb0b9a9bbb25acbcbbb5fcef518a1f 197 SUPERFAMILY SSF160904 2 186 4.45E-34 T 12-10-2018 UA74_24015 afed8cfd0d9101a0c546a0e061e60d28 448 Pfam PF01546 Peptidase family M20/M25/M40 101 429 3.0E-29 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 UA74_24015 afed8cfd0d9101a0c546a0e061e60d28 448 SUPERFAMILY SSF53187 29 434 1.83E-78 T 12-10-2018 UA74_24015 afed8cfd0d9101a0c546a0e061e60d28 448 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 31 430 2.1E-111 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 UA74_24015 afed8cfd0d9101a0c546a0e061e60d28 448 Gene3D G3DSA:3.40.630.10 44 427 2.6E-126 T 12-10-2018 UA74_24015 afed8cfd0d9101a0c546a0e061e60d28 448 Gene3D G3DSA:3.30.70.360 236 351 2.6E-126 T 12-10-2018 UA74_24015 afed8cfd0d9101a0c546a0e061e60d28 448 SUPERFAMILY SSF55031 236 353 1.13E-22 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UA74_24015 afed8cfd0d9101a0c546a0e061e60d28 448 PIRSF PIRSF001235 26 436 3.0E-125 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 UA74_00335 8e83f6bd51838aacae3103e0483fa68c 224 SUPERFAMILY SSF55068 15 214 1.96E-78 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_00335 8e83f6bd51838aacae3103e0483fa68c 224 Gene3D G3DSA:3.30.1060.10 5 219 6.5E-93 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_00335 8e83f6bd51838aacae3103e0483fa68c 224 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 49 204 6.2E-65 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_00335 8e83f6bd51838aacae3103e0483fa68c 224 Pfam PF01625 Peptide methionine sulfoxide reductase 49 204 2.3E-67 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_00335 8e83f6bd51838aacae3103e0483fa68c 224 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 47 210 37.236 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UA74_08735 5e28847bd03ab14c49d076715160641a 230 SUPERFAMILY SSF46785 2 62 3.75E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_08735 5e28847bd03ab14c49d076715160641a 230 SMART SM00529 26 125 1.8E-41 T 12-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 UA74_08735 5e28847bd03ab14c49d076715160641a 230 Gene3D G3DSA:1.10.60.10 74 140 7.4E-30 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 UA74_08735 5e28847bd03ab14c49d076715160641a 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 62 3.8E-20 T 12-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 UA74_08735 5e28847bd03ab14c49d076715160641a 230 Pfam PF04023 FeoA domain 162 229 6.1E-5 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 UA74_08735 5e28847bd03ab14c49d076715160641a 230 Gene3D G3DSA:1.10.10.10 1 72 2.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08735 5e28847bd03ab14c49d076715160641a 230 SUPERFAMILY SSF47979 65 137 1.44E-25 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 UA74_08735 5e28847bd03ab14c49d076715160641a 230 SUPERFAMILY SSF50037 130 228 5.26E-20 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal UA74_08735 5e28847bd03ab14c49d076715160641a 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 2.8E-28 T 12-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 UA74_08735 5e28847bd03ab14c49d076715160641a 230 Gene3D G3DSA:2.30.30.90 151 229 4.8E-10 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain UA74_12105 4e8950c5b1b378acbae13e3acaf74bcc 78 Pfam PF00367 phosphotransferase system, EIIB 8 40 4.8E-14 T 12-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UA74_12105 4e8950c5b1b378acbae13e3acaf74bcc 78 Gene3D G3DSA:3.30.1360.60 1 78 2.5E-26 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UA74_12105 4e8950c5b1b378acbae13e3acaf74bcc 78 SUPERFAMILY SSF55604 6 77 2.48E-21 T 12-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UA74_12105 4e8950c5b1b378acbae13e3acaf74bcc 78 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 3 64 1.0E-15 T 12-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 UA74_20480 37568d302f34729ffa5cebbb88b94116 331 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 4 330 2.1E-91 T 12-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 UA74_20480 37568d302f34729ffa5cebbb88b94116 331 Pfam PF00107 Zinc-binding dehydrogenase 156 273 7.0E-22 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_20480 37568d302f34729ffa5cebbb88b94116 331 Gene3D G3DSA:3.90.180.10 13 327 2.1E-88 T 12-10-2018 UA74_20480 37568d302f34729ffa5cebbb88b94116 331 Gene3D G3DSA:3.40.50.720 128 272 2.1E-88 T 12-10-2018 UA74_20480 37568d302f34729ffa5cebbb88b94116 331 SUPERFAMILY SSF51735 122 284 4.52E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_20480 37568d302f34729ffa5cebbb88b94116 331 SUPERFAMILY SSF50129 1 152 2.36E-33 T 12-10-2018 IPR011032 GroES-like superfamily UA74_20480 37568d302f34729ffa5cebbb88b94116 331 SMART SM00829 13 328 7.5E-39 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_26085 b598ade679cc1405adde2694d6198e20 779 Pfam PF12826 Helix-hairpin-helix motif 538 601 4.2E-21 T 12-10-2018 UA74_26085 b598ade679cc1405adde2694d6198e20 779 SMART SM00292 620 697 7.4E-8 T 12-10-2018 IPR001357 BRCT domain UA74_26085 b598ade679cc1405adde2694d6198e20 779 Gene3D G3DSA:3.40.50.10190 618 699 8.7E-21 T 12-10-2018 IPR036420 BRCT domain superfamily UA74_26085 b598ade679cc1405adde2694d6198e20 779 SUPERFAMILY SSF56091 23 337 1.3E-111 T 12-10-2018 UA74_26085 b598ade679cc1405adde2694d6198e20 779 Gene3D G3DSA:1.10.150.20 454 532 1.7E-11 T 12-10-2018 UA74_26085 b598ade679cc1405adde2694d6198e20 779 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 134 163 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site UA74_26085 b598ade679cc1405adde2694d6198e20 779 Gene3D G3DSA:2.20.70.80 412 451 3.2E-9 T 12-10-2018 UA74_26085 b598ade679cc1405adde2694d6198e20 779 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 352 367 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site UA74_26085 b598ade679cc1405adde2694d6198e20 779 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 428 456 8.2E-10 T 12-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 UA74_26085 b598ade679cc1405adde2694d6198e20 779 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 622 689 2.6E-9 T 12-10-2018 IPR001357 BRCT domain UA74_26085 b598ade679cc1405adde2694d6198e20 779 SUPERFAMILY SSF47781 424 611 6.67E-49 T 12-10-2018 IPR010994 RuvA domain 2-like UA74_26085 b598ade679cc1405adde2694d6198e20 779 SUPERFAMILY SSF52113 622 691 1.11E-14 T 12-10-2018 IPR036420 BRCT domain superfamily UA74_26085 b598ade679cc1405adde2694d6198e20 779 SUPERFAMILY SSF50249 338 421 3.6E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_26085 b598ade679cc1405adde2694d6198e20 779 Gene3D G3DSA:1.10.287.610 13 88 4.9E-26 T 12-10-2018 UA74_26085 b598ade679cc1405adde2694d6198e20 779 Gene3D G3DSA:1.10.150.20 533 613 5.8E-27 T 12-10-2018 UA74_26085 b598ade679cc1405adde2694d6198e20 779 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 342 419 3.1E-31 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 UA74_26085 b598ade679cc1405adde2694d6198e20 779 SMART SM00532 24 470 6.2E-257 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 UA74_26085 b598ade679cc1405adde2694d6198e20 779 Gene3D G3DSA:2.40.50.140 339 410 1.4E-28 T 12-10-2018 UA74_26085 b598ade679cc1405adde2694d6198e20 779 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 24 339 1.1E-119 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 UA74_26085 b598ade679cc1405adde2694d6198e20 779 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 32 689 8.1E-238 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 UA74_26085 b598ade679cc1405adde2694d6198e20 779 Gene3D G3DSA:3.30.470.90 89 338 4.4E-100 T 12-10-2018 UA74_26085 b598ade679cc1405adde2694d6198e20 779 Hamap MF_01588 DNA ligase [ligA]. 23 694 50.028 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 UA74_26085 b598ade679cc1405adde2694d6198e20 779 PIRSF PIRSF001604 18 698 3.3E-230 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 UA74_01375 35151f6e3f5fd942981ccf8a20026445 615 Gene3D G3DSA:3.20.20.300 47 425 6.7E-124 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 UA74_01375 35151f6e3f5fd942981ccf8a20026445 615 Gene3D G3DSA:3.40.50.1700 428 613 4.7E-28 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 UA74_01375 35151f6e3f5fd942981ccf8a20026445 615 SUPERFAMILY SSF51445 48 438 6.74E-102 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_01375 35151f6e3f5fd942981ccf8a20026445 615 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 445 611 3.1E-10 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UA74_01375 35151f6e3f5fd942981ccf8a20026445 615 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 64 403 2.6E-106 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_01375 35151f6e3f5fd942981ccf8a20026445 615 SUPERFAMILY SSF52279 445 612 4.05E-13 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 UA74_14545 f6b3cfb7831aeedbb1cd101611e2dd5f 172 Pfam PF00857 Isochorismatase family 4 141 1.5E-26 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 UA74_14545 f6b3cfb7831aeedbb1cd101611e2dd5f 172 Gene3D G3DSA:3.40.50.850 1 170 4.2E-36 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_14545 f6b3cfb7831aeedbb1cd101611e2dd5f 172 SUPERFAMILY SSF52499 2 137 6.02E-32 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_16975 a5ccbbc1cbd69efefd3f7148ac3d9a4d 116 SUPERFAMILY SSF47336 34 110 5.63E-10 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16975 a5ccbbc1cbd69efefd3f7148ac3d9a4d 116 Gene3D G3DSA:1.10.1200.10 33 111 6.5E-14 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16975 a5ccbbc1cbd69efefd3f7148ac3d9a4d 116 Pfam PF00550 Phosphopantetheine attachment site 45 91 1.2E-5 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_00800 94c1eb168803467ee7a6030eb029a3d1 355 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 5 355 45.82 T 12-10-2018 IPR024892 Putative phenylalanine aminotransferase UA74_00800 94c1eb168803467ee7a6030eb029a3d1 355 Pfam PF00155 Aminotransferase class I and II 25 348 6.7E-50 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_00800 94c1eb168803467ee7a6030eb029a3d1 355 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 351 2.4E-86 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UA74_00800 94c1eb168803467ee7a6030eb029a3d1 355 Gene3D G3DSA:3.40.640.10 36 266 3.2E-122 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_00800 94c1eb168803467ee7a6030eb029a3d1 355 Gene3D G3DSA:3.90.1150.10 10 347 3.2E-122 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_00800 94c1eb168803467ee7a6030eb029a3d1 355 SUPERFAMILY SSF53383 18 349 7.7E-75 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_00800 94c1eb168803467ee7a6030eb029a3d1 355 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 354 49.04 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UA74_00800 94c1eb168803467ee7a6030eb029a3d1 355 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 UA74_23245 36b55e2572cc7b5c4fe3ce19d74cb194 109 Gene3D G3DSA:3.30.470.20 17 107 1.6E-9 T 12-10-2018 UA74_23245 36b55e2572cc7b5c4fe3ce19d74cb194 109 SUPERFAMILY SSF56059 33 105 2.44E-6 T 12-10-2018 UA74_00065 578a658345ac1b3c1d58ba68b91fc6aa 227 Pfam PF09449 Domain of unknown function (DUF2020) 90 227 4.4E-36 T 12-10-2018 IPR018567 Domain of unknown function DUF2020 UA74_00065 578a658345ac1b3c1d58ba68b91fc6aa 227 SUPERFAMILY SSF55724 90 227 1.26E-42 T 12-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich UA74_00065 578a658345ac1b3c1d58ba68b91fc6aa 227 Gene3D G3DSA:3.40.1000.10 78 227 1.5E-50 T 12-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich UA74_03130 2d96aece4754d17f11eb5dc2f8bc37f7 135 Pfam PF00411 Ribosomal protein S11 25 134 1.1E-48 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UA74_03130 2d96aece4754d17f11eb5dc2f8bc37f7 135 ProSitePatterns PS00054 Ribosomal protein S11 signature. 103 125 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site UA74_03130 2d96aece4754d17f11eb5dc2f8bc37f7 135 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 135 33.894 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UA74_03130 2d96aece4754d17f11eb5dc2f8bc37f7 135 Gene3D G3DSA:3.30.420.80 9 135 8.7E-54 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 UA74_03130 2d96aece4754d17f11eb5dc2f8bc37f7 135 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 16 132 1.5E-58 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_03130 2d96aece4754d17f11eb5dc2f8bc37f7 135 PIRSF PIRSF002131 6 135 2.6E-53 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UA74_03130 2d96aece4754d17f11eb5dc2f8bc37f7 135 SUPERFAMILY SSF53137 20 135 3.2E-49 T 12-10-2018 UA74_14210 2146ff289c19b919c30576908ca22b62 423 Pfam PF07005 Putative sugar-binding N-terminal domain 5 229 2.2E-65 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain UA74_14210 2146ff289c19b919c30576908ca22b62 423 Gene3D G3DSA:3.40.980.20 242 422 6.4E-42 T 12-10-2018 UA74_14210 2146ff289c19b919c30576908ca22b62 423 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 254 415 6.3E-33 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain UA74_14210 2146ff289c19b919c30576908ca22b62 423 Gene3D G3DSA:3.40.50.10840 3 238 1.7E-81 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily UA74_14210 2146ff289c19b919c30576908ca22b62 423 SUPERFAMILY SSF142764 5 422 3.14E-105 T 12-10-2018 UA74_29560 779744bc77254618407296c94372ef16 324 Pfam PF00005 ABC transporter 18 156 1.3E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_29560 779744bc77254618407296c94372ef16 324 SUPERFAMILY SSF52540 2 223 1.18E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29560 779744bc77254618407296c94372ef16 324 Gene3D G3DSA:3.40.50.300 1 230 8.7E-57 T 12-10-2018 UA74_29560 779744bc77254618407296c94372ef16 324 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_29560 779744bc77254618407296c94372ef16 324 SMART SM00382 26 204 5.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28790 9edc608f2cbf86d4331fb798063775bb 323 Gene3D G3DSA:3.90.550.10 7 236 1.5E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_28790 9edc608f2cbf86d4331fb798063775bb 323 Pfam PF00535 Glycosyl transferase family 2 12 137 1.0E-17 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_28790 9edc608f2cbf86d4331fb798063775bb 323 SUPERFAMILY SSF53448 9 237 1.62E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_12235 52badad94dcc2a4fc2a9c77cfce6c31f 418 Gene3D G3DSA:3.40.50.10300 195 418 1.6E-81 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 UA74_12235 52badad94dcc2a4fc2a9c77cfce6c31f 418 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 200 387 1.2E-66 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 UA74_12235 52badad94dcc2a4fc2a9c77cfce6c31f 418 Pfam PF02441 Flavoprotein 19 185 5.9E-39 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UA74_12235 52badad94dcc2a4fc2a9c77cfce6c31f 418 Gene3D G3DSA:3.40.50.1950 14 194 1.2E-52 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 UA74_12235 52badad94dcc2a4fc2a9c77cfce6c31f 418 SUPERFAMILY SSF52507 17 186 3.01E-56 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 UA74_12235 52badad94dcc2a4fc2a9c77cfce6c31f 418 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 19 412 2.1E-117 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 UA74_12235 52badad94dcc2a4fc2a9c77cfce6c31f 418 SUPERFAMILY SSF102645 198 416 4.84E-66 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 UA74_28255 4256593339bf9310ddcb9dd54e09e38f 564 Gene3D G3DSA:1.20.1250.20 43 437 6.2E-31 T 12-10-2018 UA74_28255 4256593339bf9310ddcb9dd54e09e38f 564 SUPERFAMILY SSF103473 44 430 1.96E-35 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_28255 4256593339bf9310ddcb9dd54e09e38f 564 Pfam PF05977 Transmembrane secretion effector 38 426 4.8E-42 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_06725 8213d7ca3d3b19fdc44d3b42baddb996 428 SMART SM00028 6 39 82.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06725 8213d7ca3d3b19fdc44d3b42baddb996 428 SMART SM00028 145 178 330.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06725 8213d7ca3d3b19fdc44d3b42baddb996 428 SMART SM00028 76 107 240.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06725 8213d7ca3d3b19fdc44d3b42baddb996 428 SMART SM00028 40 73 3.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06725 8213d7ca3d3b19fdc44d3b42baddb996 428 Gene3D G3DSA:1.25.40.10 2 123 1.2E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_06725 8213d7ca3d3b19fdc44d3b42baddb996 428 Pfam PF14559 Tetratricopeptide repeat 18 71 5.2E-6 T 12-10-2018 UA74_06725 8213d7ca3d3b19fdc44d3b42baddb996 428 SUPERFAMILY SSF48452 6 173 9.25E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_06725 8213d7ca3d3b19fdc44d3b42baddb996 428 Gene3D G3DSA:1.25.40.10 124 196 2.7E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_06725 8213d7ca3d3b19fdc44d3b42baddb996 428 Pfam PF13432 Tetratricopeptide repeat 123 179 1.7E-7 T 12-10-2018 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 5 119 2.5E-16 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 251 339 5.4E-6 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 SMART SM00480 19 364 1.5E-20 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 SUPERFAMILY SSF55979 4 120 6.8E-15 T 12-10-2018 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 133 241 4.8E-16 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 Gene3D G3DSA:3.10.150.10 126 245 1.4E-22 T 12-10-2018 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 SUPERFAMILY SSF55979 131 245 1.26E-17 T 12-10-2018 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 Gene3D G3DSA:3.10.150.10 249 370 8.2E-10 T 12-10-2018 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 Gene3D G3DSA:3.10.150.10 1 123 2.2E-22 T 12-10-2018 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 SUPERFAMILY SSF55979 245 367 2.77E-9 T 12-10-2018 UA74_01240 c0a2bf66a0a56efe40b266489e1fab07 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 9 340 8.8E-41 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 UA74_24540 f00adbb49ae78fb33b4cd2f29e8f4b34 321 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 51 275 1.7E-45 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 UA74_24540 f00adbb49ae78fb33b4cd2f29e8f4b34 321 Gene3D G3DSA:3.40.50.620 29 231 2.7E-57 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_24540 f00adbb49ae78fb33b4cd2f29e8f4b34 321 PIRSF PIRSF002936 21 321 1.5E-132 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 UA74_24540 f00adbb49ae78fb33b4cd2f29e8f4b34 321 SUPERFAMILY SSF52402 27 228 6.62E-63 T 12-10-2018 UA74_24540 f00adbb49ae78fb33b4cd2f29e8f4b34 321 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 30 321 5.8E-137 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 UA74_14950 876eb71e911815b038e421a8b3563f2e 360 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 288 5.8E-29 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_14950 876eb71e911815b038e421a8b3563f2e 360 SUPERFAMILY SSF51905 5 305 6.05E-23 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_14950 876eb71e911815b038e421a8b3563f2e 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 5.2E-8 T 12-10-2018 UA74_14950 876eb71e911815b038e421a8b3563f2e 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 91 109 5.2E-8 T 12-10-2018 UA74_14950 876eb71e911815b038e421a8b3563f2e 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 5.2E-8 T 12-10-2018 UA74_14950 876eb71e911815b038e421a8b3563f2e 360 Gene3D G3DSA:3.50.50.100 2 352 3.1E-44 T 12-10-2018 UA74_06775 e06f20ed486a941b7f59b490b56ea96d 186 SUPERFAMILY SSF52788 1 181 3.27E-24 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily UA74_06775 e06f20ed486a941b7f59b490b56ea96d 186 Gene3D G3DSA:3.40.50.2300 1 185 5.3E-34 T 12-10-2018 UA74_06775 e06f20ed486a941b7f59b490b56ea96d 186 SMART SM00226 1 180 2.7E-10 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UA74_06775 e06f20ed486a941b7f59b490b56ea96d 186 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 86 5.4E-17 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UA74_26720 e9c4e2c60468d922a21c70e4e06d3390 666 Pfam PF14517 Tachylectin 124 217 3.7E-13 T 12-10-2018 IPR023294 Tachylectin 2 UA74_26720 e9c4e2c60468d922a21c70e4e06d3390 666 Gene3D G3DSA:2.115.10.10 92 321 9.1E-31 T 12-10-2018 UA74_26720 e9c4e2c60468d922a21c70e4e06d3390 666 SUPERFAMILY SSF50934 140 311 2.22E-13 T 12-10-2018 IPR036813 Tachylectin 2 superfamily UA74_26720 e9c4e2c60468d922a21c70e4e06d3390 666 SUPERFAMILY SSF89372 507 625 3.79E-7 T 12-10-2018 UA74_26720 e9c4e2c60468d922a21c70e4e06d3390 666 SUPERFAMILY SSF89372 278 528 7.85E-14 T 12-10-2018 UA74_06710 ac1121e731fabfd277db1b7de17c1510 84 Gene3D G3DSA:3.30.1490.20 1 61 6.9E-15 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_22885 e36120bd9f5e549a1ac465f5791b873a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 3.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22885 e36120bd9f5e549a1ac465f5791b873a 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 3.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22885 e36120bd9f5e549a1ac465f5791b873a 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 2.1E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22885 e36120bd9f5e549a1ac465f5791b873a 198 SUPERFAMILY SSF46689 4 72 1.9E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_22885 e36120bd9f5e549a1ac465f5791b873a 198 Gene3D G3DSA:1.10.357.10 2 193 5.6E-27 T 12-10-2018 UA74_22885 e36120bd9f5e549a1ac465f5791b873a 198 SUPERFAMILY SSF48498 78 186 8.9E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_03535 d49e8e98eac3ec358f079da246ad88c8 230 Pfam PF00106 short chain dehydrogenase 6 146 7.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_03535 d49e8e98eac3ec358f079da246ad88c8 230 Gene3D G3DSA:3.40.50.720 1 229 2.4E-38 T 12-10-2018 UA74_03535 d49e8e98eac3ec358f079da246ad88c8 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 34 1.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_03535 d49e8e98eac3ec358f079da246ad88c8 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 142 1.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_03535 d49e8e98eac3ec358f079da246ad88c8 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 183 1.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_03535 d49e8e98eac3ec358f079da246ad88c8 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 124 1.8E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_03535 d49e8e98eac3ec358f079da246ad88c8 230 SUPERFAMILY SSF51735 5 198 3.81E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14765 2b6ad971047f444573453fba6c445b81 161 Pfam PF13302 Acetyltransferase (GNAT) domain 3 136 1.0E-19 T 12-10-2018 IPR000182 GNAT domain UA74_14765 2b6ad971047f444573453fba6c445b81 161 Gene3D G3DSA:3.40.630.30 2 161 1.6E-27 T 12-10-2018 UA74_14765 2b6ad971047f444573453fba6c445b81 161 SUPERFAMILY SSF55729 3 158 3.24E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_29315 09c3406de73cd7a50fd4900475fe8b96 107 SUPERFAMILY SSF103481 5 105 1.07E-18 T 12-10-2018 UA74_29315 09c3406de73cd7a50fd4900475fe8b96 107 Gene3D G3DSA:1.10.3730.20 1 105 5.5E-31 T 12-10-2018 UA74_29315 09c3406de73cd7a50fd4900475fe8b96 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 3.7E-24 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 UA74_05680 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 395 3.0E-127 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 UA74_05680 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 Gene3D G3DSA:3.40.50.2000 6 390 1.5E-132 T 12-10-2018 UA74_05680 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 SUPERFAMILY SSF53756 1 393 4.4E-75 T 12-10-2018 UA74_05680 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 Gene3D G3DSA:3.40.50.2000 216 378 1.5E-132 T 12-10-2018 UA74_05680 eddc72ac5f75ce17ec1bea3ff1e56ffa 397 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 228 366 1.8E-12 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 UA74_14970 87f5637a417404f73eade7d6cc250c54 288 SUPERFAMILY SSF51735 4 248 1.08E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14970 87f5637a417404f73eade7d6cc250c54 288 Gene3D G3DSA:3.90.25.10 126 264 3.8E-54 T 12-10-2018 UA74_14970 87f5637a417404f73eade7d6cc250c54 288 Gene3D G3DSA:3.40.50.720 5 262 3.8E-54 T 12-10-2018 UA74_06975 deece2e7793995dede8fdccb5b452e00 369 PIRSF PIRSF038945 11 368 1.0E-163 T 12-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 UA74_06975 deece2e7793995dede8fdccb5b452e00 369 Gene3D G3DSA:3.40.50.1100 39 343 3.6E-123 T 12-10-2018 UA74_06975 deece2e7793995dede8fdccb5b452e00 369 SUPERFAMILY SSF53686 19 348 5.5E-102 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_06975 deece2e7793995dede8fdccb5b452e00 369 TIGRFAM TIGR00260 thrC: threonine synthase 28 343 4.2E-90 T 12-10-2018 IPR004450 Threonine synthase-like UA74_06975 deece2e7793995dede8fdccb5b452e00 369 Gene3D G3DSA:3.40.50.1100 78 174 3.6E-123 T 12-10-2018 UA74_06975 deece2e7793995dede8fdccb5b452e00 369 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 42 336 1.5E-75 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_06975 deece2e7793995dede8fdccb5b452e00 369 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 70 83 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 UA74_12195 9752654f2d7b72156c3bfa1626426e5c 456 Gene3D G3DSA:2.30.40.10 16 441 5.6E-121 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_12195 9752654f2d7b72156c3bfa1626426e5c 456 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 23 446 1.3E-127 T 12-10-2018 UA74_12195 9752654f2d7b72156c3bfa1626426e5c 456 Gene3D G3DSA:3.20.20.140 62 389 5.6E-121 T 12-10-2018 UA74_12195 9752654f2d7b72156c3bfa1626426e5c 456 ProSitePatterns PS00483 Dihydroorotase signature 2. 323 334 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12195 9752654f2d7b72156c3bfa1626426e5c 456 Pfam PF01979 Amidohydrolase family 58 441 8.9E-19 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_12195 9752654f2d7b72156c3bfa1626426e5c 456 SUPERFAMILY SSF51338 21 450 9.99E-23 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_12195 9752654f2d7b72156c3bfa1626426e5c 456 Hamap MF_00220_B Dihydroorotase [pyrC]. 11 446 40.501 T 12-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12195 9752654f2d7b72156c3bfa1626426e5c 456 SUPERFAMILY SSF51556 61 388 2.38E-87 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_09250 ffde07c69ca4520a17c6cc8831197396 100 Gene3D G3DSA:3.30.70.1120 1 98 1.4E-24 T 12-10-2018 IPR036746 TT1725-like superfamily UA74_09250 ffde07c69ca4520a17c6cc8831197396 100 SUPERFAMILY SSF103007 3 96 8.76E-31 T 12-10-2018 IPR036746 TT1725-like superfamily UA74_09250 ffde07c69ca4520a17c6cc8831197396 100 Pfam PF04456 Protein of unknown function (DUF503) 5 91 3.8E-33 T 12-10-2018 IPR007546 Protein of unknown function DUF503 UA74_12725 b4ce353030a9afb6285a234e8cd0b257 173 SUPERFAMILY SSF54427 18 172 2.53E-37 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_12725 b4ce353030a9afb6285a234e8cd0b257 173 Gene3D G3DSA:3.10.450.50 12 173 2.8E-38 T 12-10-2018 UA74_12725 b4ce353030a9afb6285a234e8cd0b257 173 Pfam PF00866 Ring hydroxylating beta subunit 34 166 1.6E-17 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 UA74_16840 9e311750bf54d94d566ef592489df293 497 Gene3D G3DSA:3.40.50.1820 2 493 5.5E-121 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16840 9e311750bf54d94d566ef592489df293 497 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 170 185 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site UA74_16840 9e311750bf54d94d566ef592489df293 497 SUPERFAMILY SSF53474 4 489 7.7E-98 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16840 9e311750bf54d94d566ef592489df293 497 Pfam PF00135 Carboxylesterase family 3 476 1.3E-84 T 12-10-2018 IPR002018 Carboxylesterase, type B UA74_28535 58db3ca1b9eac555dce8993715b42293 200 Gene3D G3DSA:1.10.10.10 117 195 3.2E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28535 58db3ca1b9eac555dce8993715b42293 200 Gene3D G3DSA:1.10.1740.10 19 106 1.1E-14 T 12-10-2018 UA74_28535 58db3ca1b9eac555dce8993715b42293 200 SUPERFAMILY SSF88946 22 106 4.91E-19 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_28535 58db3ca1b9eac555dce8993715b42293 200 Pfam PF04542 Sigma-70 region 2 40 105 1.2E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_28535 58db3ca1b9eac555dce8993715b42293 200 SUPERFAMILY SSF88659 113 193 7.52E-7 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_28535 58db3ca1b9eac555dce8993715b42293 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 192 5.2E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_08245 e78e778af2a48a9f2dc147d4951ee2aa 74 SUPERFAMILY SSF54862 4 63 4.02E-9 T 12-10-2018 UA74_08245 e78e778af2a48a9f2dc147d4951ee2aa 74 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 8 59 5.5E-10 T 12-10-2018 UA74_08245 e78e778af2a48a9f2dc147d4951ee2aa 74 Gene3D G3DSA:3.30.70.20 2 63 5.3E-15 T 12-10-2018 UA74_08245 e78e778af2a48a9f2dc147d4951ee2aa 74 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 4.0E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_08245 e78e778af2a48a9f2dc147d4951ee2aa 74 PRINTS PR00352 3Fe-4S ferredoxin signature 19 29 4.0E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_08245 e78e778af2a48a9f2dc147d4951ee2aa 74 PRINTS PR00352 3Fe-4S ferredoxin signature 8 19 4.0E-6 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_17375 10c514dc0f5e04e5e86abcc62c8989eb 336 Gene3D G3DSA:1.10.260.40 71 145 1.6E-6 T 12-10-2018 UA74_17375 10c514dc0f5e04e5e86abcc62c8989eb 336 Gene3D G3DSA:3.30.450.180 152 328 5.2E-14 T 12-10-2018 UA74_17375 10c514dc0f5e04e5e86abcc62c8989eb 336 SUPERFAMILY SSF47413 75 124 2.38E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_17375 10c514dc0f5e04e5e86abcc62c8989eb 336 SMART SM00530 49 126 1.9E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_17375 10c514dc0f5e04e5e86abcc62c8989eb 336 Pfam PF13560 Helix-turn-helix domain 53 129 1.4E-14 T 12-10-2018 UA74_01165 a82dc38fb549e6a5deb4d0ee70882fb2 156 Gene3D G3DSA:1.10.10.410 94 154 5.2E-12 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal UA74_01165 a82dc38fb549e6a5deb4d0ee70882fb2 156 SUPERFAMILY SSF89095 4 154 2.41E-30 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 UA74_01165 a82dc38fb549e6a5deb4d0ee70882fb2 156 Pfam PF09424 Yqey-like protein 5 154 9.7E-42 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 UA74_01165 a82dc38fb549e6a5deb4d0ee70882fb2 156 Gene3D G3DSA:1.10.1510.10 2 93 1.0E-22 T 12-10-2018 UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 Gene3D G3DSA:3.40.50.720 402 681 2.7E-57 T 12-10-2018 UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 421 611 0.0045 T 12-10-2018 UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 500 511 2.4E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 422 439 2.4E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 574 593 2.4E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 595 612 2.4E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 548 564 2.4E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 SMART SM01007 9 211 2.8E-31 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 SUPERFAMILY SSF53639 4 214 9.81E-31 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 208 4.1E-24 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 SUPERFAMILY SSF51735 414 681 2.99E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 8 684 0.0 T 12-10-2018 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 Pfam PF00106 short chain dehydrogenase 422 607 2.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_23850 8c2c1f63c712fd80c5c91033ef14d748 684 Gene3D G3DSA:3.40.225.10 6 216 5.4E-52 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UA74_28525 1f01d4ade9980563adccc8e5f094c913 224 SUPERFAMILY SSF110395 5 221 1.57E-42 T 12-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 UA74_28525 1f01d4ade9980563adccc8e5f094c913 224 Gene3D G3DSA:3.20.20.380 5 224 1.4E-47 T 12-10-2018 IPR036822 Copper homeostasis (CutC) domain superfamily GO:0005507|GO:0055070 Reactome: R-HSA-936837 UA74_28525 1f01d4ade9980563adccc8e5f094c913 224 Pfam PF03932 CutC family 7 198 3.4E-31 T 12-10-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 UA74_03995 7b5d2addd5128ce5161ab5f45825d3db 521 Pfam PF06259 Alpha/beta hydrolase 300 464 5.0E-30 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 UA74_03995 7b5d2addd5128ce5161ab5f45825d3db 521 Gene3D G3DSA:1.10.287.1060 7 94 2.8E-7 T 12-10-2018 UA74_03995 7b5d2addd5128ce5161ab5f45825d3db 521 SUPERFAMILY SSF53474 358 461 5.28E-5 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_03995 7b5d2addd5128ce5161ab5f45825d3db 521 SUPERFAMILY SSF140453 11 95 1.05E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 Gene3D G3DSA:1.20.58.760 414 615 1.5E-68 T 12-10-2018 UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 Pfam PF01434 Peptidase family M41 395 602 4.5E-76 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 SMART SM00382 196 335 5.4E-25 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 639 36.011 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 SUPERFAMILY SSF52540 156 403 2.05E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 SUPERFAMILY SSF140990 414 607 3.01E-67 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 113 603 6.1E-225 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 ProSitePatterns PS00674 AAA-protein family signature. 303 321 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 Gene3D G3DSA:3.40.50.300 151 332 1.1E-68 T 12-10-2018 UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 200 331 1.8E-45 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_01545 b50e7896f0fd69f847110a1c24f04841 809 Gene3D G3DSA:1.10.8.60 334 411 7.8E-25 T 12-10-2018 UA74_10845 688ca94070c68641a26ff2286f58d731 643 SUPERFAMILY SSF46894 2 83 1.93E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_10845 688ca94070c68641a26ff2286f58d731 643 Pfam PF00486 Transcriptional regulatory protein, C terminal 22 83 1.6E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_10845 688ca94070c68641a26ff2286f58d731 643 Pfam PF00931 NB-ARC domain 313 495 9.8E-9 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_10845 688ca94070c68641a26ff2286f58d731 643 SMART SM00862 15 103 8.8E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_10845 688ca94070c68641a26ff2286f58d731 643 SUPERFAMILY SSF52540 282 502 2.33E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10845 688ca94070c68641a26ff2286f58d731 643 SUPERFAMILY SSF48452 106 271 5.55E-42 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_10845 688ca94070c68641a26ff2286f58d731 643 Gene3D G3DSA:1.25.40.10 108 285 1.0E-50 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_10845 688ca94070c68641a26ff2286f58d731 643 Pfam PF03704 Bacterial transcriptional activator domain 110 255 9.6E-47 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_10845 688ca94070c68641a26ff2286f58d731 643 PRINTS PR00364 Disease resistance protein signature 313 328 7.4E-6 T 12-10-2018 UA74_10845 688ca94070c68641a26ff2286f58d731 643 PRINTS PR00364 Disease resistance protein signature 475 489 7.4E-6 T 12-10-2018 UA74_10845 688ca94070c68641a26ff2286f58d731 643 PRINTS PR00364 Disease resistance protein signature 390 404 7.4E-6 T 12-10-2018 UA74_10845 688ca94070c68641a26ff2286f58d731 643 Gene3D G3DSA:1.10.10.10 1 106 1.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10845 688ca94070c68641a26ff2286f58d731 643 SMART SM01043 110 255 5.5E-52 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_29485 a14772b80c702272d8219aec9013102b 326 Gene3D G3DSA:3.30.420.40 3 133 6.8E-25 T 12-10-2018 UA74_29485 a14772b80c702272d8219aec9013102b 326 Pfam PF00480 ROK family 12 320 2.2E-57 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_29485 a14772b80c702272d8219aec9013102b 326 Gene3D G3DSA:3.30.420.40 135 322 2.5E-48 T 12-10-2018 UA74_29485 a14772b80c702272d8219aec9013102b 326 SUPERFAMILY SSF53067 11 322 5.93E-54 T 12-10-2018 UA74_05285 6ec1d3579bbbab2f2477ae51b8ce89f0 333 SUPERFAMILY SSF50129 1 147 6.7E-37 T 12-10-2018 IPR011032 GroES-like superfamily UA74_05285 6ec1d3579bbbab2f2477ae51b8ce89f0 333 Gene3D G3DSA:3.40.50.720 123 299 5.3E-104 T 12-10-2018 UA74_05285 6ec1d3579bbbab2f2477ae51b8ce89f0 333 SMART SM00829 11 328 3.6E-40 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_05285 6ec1d3579bbbab2f2477ae51b8ce89f0 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 87 1.9E-10 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_05285 6ec1d3579bbbab2f2477ae51b8ce89f0 333 Gene3D G3DSA:3.90.180.10 15 328 5.3E-104 T 12-10-2018 UA74_05285 6ec1d3579bbbab2f2477ae51b8ce89f0 333 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_05285 6ec1d3579bbbab2f2477ae51b8ce89f0 333 Pfam PF13602 Zinc-binding dehydrogenase 185 328 3.9E-35 T 12-10-2018 UA74_05285 6ec1d3579bbbab2f2477ae51b8ce89f0 333 SUPERFAMILY SSF51735 117 295 5.09E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_01250 e73a751bb6f9455834ed90fe24e1fc9a 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.0E-18 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 UA74_01250 e73a751bb6f9455834ed90fe24e1fc9a 224 SUPERFAMILY SSF51206 4 142 9.95E-37 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like UA74_01250 e73a751bb6f9455834ed90fe24e1fc9a 224 SUPERFAMILY SSF46785 145 223 4.21E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_01250 e73a751bb6f9455834ed90fe24e1fc9a 224 Gene3D G3DSA:2.60.120.10 1 146 1.4E-46 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_01250 e73a751bb6f9455834ed90fe24e1fc9a 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 115 4.0E-24 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain UA74_01250 e73a751bb6f9455834ed90fe24e1fc9a 224 SMART SM00419 167 215 2.2E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 UA74_01250 e73a751bb6f9455834ed90fe24e1fc9a 224 SMART SM00100 10 128 3.2E-26 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain UA74_01250 e73a751bb6f9455834ed90fe24e1fc9a 224 Gene3D G3DSA:1.10.10.10 147 224 2.7E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_30170 f80dbd01493d0e0b4534928ea154121a 337 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 56 310 2.6E-36 T 12-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain UA74_30170 f80dbd01493d0e0b4534928ea154121a 337 Gene3D G3DSA:3.40.50.2300 158 287 7.1E-76 T 12-10-2018 UA74_30170 f80dbd01493d0e0b4534928ea154121a 337 SUPERFAMILY SSF53822 58 327 4.91E-73 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_30170 f80dbd01493d0e0b4534928ea154121a 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 12-10-2018 UA74_30170 f80dbd01493d0e0b4534928ea154121a 337 SUPERFAMILY SSF47413 1 56 2.63E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_30170 f80dbd01493d0e0b4534928ea154121a 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 3.4E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_30170 f80dbd01493d0e0b4534928ea154121a 337 Gene3D G3DSA:1.10.260.40 1 56 1.2E-23 T 12-10-2018 UA74_30170 f80dbd01493d0e0b4534928ea154121a 337 Gene3D G3DSA:3.40.50.2300 58 304 7.1E-76 T 12-10-2018 UA74_30170 f80dbd01493d0e0b4534928ea154121a 337 SMART SM00354 1 68 1.0E-29 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_04705 87c695e85b53bb301e7d1f439d025255 598 SUPERFAMILY SSF52540 142 426 1.11E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04705 87c695e85b53bb301e7d1f439d025255 598 Pfam PF00271 Helicase conserved C-terminal domain 300 408 4.5E-29 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_04705 87c695e85b53bb301e7d1f439d025255 598 SMART SM00490 327 408 1.3E-33 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_04705 87c695e85b53bb301e7d1f439d025255 598 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 220 228 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site UA74_04705 87c695e85b53bb301e7d1f439d025255 598 Pfam PF00270 DEAD/DEAH box helicase 97 257 4.7E-49 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_04705 87c695e85b53bb301e7d1f439d025255 598 Gene3D G3DSA:3.40.50.300 285 457 1.6E-47 T 12-10-2018 UA74_04705 87c695e85b53bb301e7d1f439d025255 598 Gene3D G3DSA:3.40.50.300 56 277 8.5E-72 T 12-10-2018 UA74_04705 87c695e85b53bb301e7d1f439d025255 598 SMART SM00487 91 287 1.3E-53 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_11390 bee13c8324c6201133266b530e5fab21 242 SMART SM00422 12 86 3.9E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_11390 bee13c8324c6201133266b530e5fab21 242 SUPERFAMILY SSF46955 24 85 2.93E-12 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_11390 bee13c8324c6201133266b530e5fab21 242 Gene3D G3DSA:1.10.1660.10 27 176 7.0E-19 T 12-10-2018 UA74_11390 bee13c8324c6201133266b530e5fab21 242 Pfam PF00376 MerR family regulatory protein 13 54 9.1E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 Gene3D G3DSA:1.10.630.10 42 436 2.9E-121 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 SUPERFAMILY SSF48264 47 435 1.83E-87 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00359 B-class P450 signature 169 185 1.6E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00359 B-class P450 signature 122 133 1.6E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00359 B-class P450 signature 310 321 1.6E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00359 B-class P450 signature 356 371 1.6E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00359 B-class P450 signature 377 386 1.6E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00359 B-class P450 signature 186 201 1.6E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00359 B-class P450 signature 224 246 1.6E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00359 B-class P450 signature 386 397 1.6E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00359 B-class P450 signature 328 355 1.6E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00385 P450 superfamily signature 275 292 2.8E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00385 P450 superfamily signature 310 321 2.8E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00385 P450 superfamily signature 386 397 2.8E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 PRINTS PR00385 P450 superfamily signature 377 386 2.8E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 Pfam PF00067 Cytochrome P450 66 300 2.1E-12 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 Pfam PF00067 Cytochrome P450 311 398 1.3E-12 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06865 344157275d0b8f6a04f554856e96aaed 436 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 379 388 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 SMART SM00729 58 292 2.1E-7 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 SMART SM00729 521 750 0.0061 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 Pfam PF04055 Radical SAM superfamily 62 239 3.2E-11 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 517 829 9.1E-109 T 12-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 Pfam PF04055 Radical SAM superfamily 525 696 7.6E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 Hamap MF_01611 FO synthase subunit 1 [cofG]. 54 386 49.514 T 12-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 Gene3D G3DSA:3.20.20.70 1 303 2.2E-53 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 485 832 3.0E-152 T 12-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 SUPERFAMILY SSF102114 18 356 1.19E-38 T 12-10-2018 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 55 384 7.4E-143 T 12-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 SUPERFAMILY SSF102114 489 820 1.05E-45 T 12-10-2018 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 Hamap MF_01612 FO synthase subunit 2 [cofH]. 460 833 48.734 T 12-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 UA74_17915 4ad3ae22a15fccf4b49cf1b1e3db443f 857 Gene3D G3DSA:3.20.20.70 477 834 8.1E-49 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_13505 d0f78b2c18e7a27b6f06edc39f6cb8d7 312 SUPERFAMILY SSF52540 22 268 9.35E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13505 d0f78b2c18e7a27b6f06edc39f6cb8d7 312 SMART SM00382 46 246 5.0E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13505 d0f78b2c18e7a27b6f06edc39f6cb8d7 312 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_13505 d0f78b2c18e7a27b6f06edc39f6cb8d7 312 Gene3D G3DSA:3.40.50.300 22 308 2.7E-58 T 12-10-2018 UA74_13505 d0f78b2c18e7a27b6f06edc39f6cb8d7 312 Pfam PF00005 ABC transporter 37 197 3.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13505 d0f78b2c18e7a27b6f06edc39f6cb8d7 312 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 246 268 9.3E-10 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal UA74_14240 e594971ba83451cd3971cb0bb3c75802 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 68 8.0E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14240 e594971ba83451cd3971cb0bb3c75802 201 SUPERFAMILY SSF46689 17 82 2.99E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14240 e594971ba83451cd3971cb0bb3c75802 201 Gene3D G3DSA:1.10.357.10 13 200 3.8E-50 T 12-10-2018 UA74_14240 e594971ba83451cd3971cb0bb3c75802 201 SUPERFAMILY SSF48498 89 196 5.19E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_10140 8e274e3473ec5b0094ac17f9951c611e 388 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 118 132 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site UA74_10140 8e274e3473ec5b0094ac17f9951c611e 388 Pfam PF00348 Polyprenyl synthetase 66 311 6.0E-53 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 UA74_10140 8e274e3473ec5b0094ac17f9951c611e 388 Gene3D G3DSA:1.10.600.10 26 388 6.1E-113 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_10140 8e274e3473ec5b0094ac17f9951c611e 388 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 262 274 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site UA74_10140 8e274e3473ec5b0094ac17f9951c611e 388 SUPERFAMILY SSF48576 57 387 6.37E-73 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_08465 de9aae04909f6ec2fb6f4fe61f7f756f 167 TIGRFAM TIGR00576 dut: dUTP diphosphatase 7 148 1.6E-45 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 UA74_08465 de9aae04909f6ec2fb6f4fe61f7f756f 167 Gene3D G3DSA:2.70.40.10 2 152 1.1E-48 T 12-10-2018 IPR036157 dUTPase-like superfamily UA74_08465 de9aae04909f6ec2fb6f4fe61f7f756f 167 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 4 149 29.722 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 UA74_08465 de9aae04909f6ec2fb6f4fe61f7f756f 167 SUPERFAMILY SSF51283 4 148 1.96E-42 T 12-10-2018 IPR036157 dUTPase-like superfamily UA74_08465 de9aae04909f6ec2fb6f4fe61f7f756f 167 Pfam PF00692 dUTPase 16 148 8.1E-27 T 12-10-2018 IPR029054 dUTPase-like UA74_28735 bbcaebc82366dc1e8b8b5ef65ce3340c 207 Gene3D G3DSA:1.10.340.30 20 201 4.3E-70 T 12-10-2018 UA74_28735 bbcaebc82366dc1e8b8b5ef65ce3340c 207 Pfam PF03352 Methyladenine glycosylase 25 195 3.7E-65 T 12-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 UA74_28735 bbcaebc82366dc1e8b8b5ef65ce3340c 207 SUPERFAMILY SSF48150 21 198 6.5E-66 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_02160 e5d4b964ac6a5328cbbeb65b5149ec17 307 Pfam PF00296 Luciferase-like monooxygenase 14 280 2.1E-24 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_02160 e5d4b964ac6a5328cbbeb65b5149ec17 307 Gene3D G3DSA:3.20.20.30 15 297 1.2E-36 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_02160 e5d4b964ac6a5328cbbeb65b5149ec17 307 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 12 305 4.4E-98 T 12-10-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted UA74_02160 e5d4b964ac6a5328cbbeb65b5149ec17 307 SUPERFAMILY SSF51679 14 283 1.18E-41 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_24300 6e83d6d24f0dcba50cb7264974665ea3 311 SUPERFAMILY SSF46689 260 309 7.62E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_24300 6e83d6d24f0dcba50cb7264974665ea3 311 SUPERFAMILY SSF52317 1 189 5.8E-43 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_24300 6e83d6d24f0dcba50cb7264974665ea3 311 Gene3D G3DSA:3.40.50.880 2 204 8.2E-51 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_24300 6e83d6d24f0dcba50cb7264974665ea3 311 Gene3D G3DSA:1.10.10.60 207 311 1.2E-26 T 12-10-2018 UA74_24300 6e83d6d24f0dcba50cb7264974665ea3 311 SMART SM00342 223 306 3.5E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_24300 6e83d6d24f0dcba50cb7264974665ea3 311 Pfam PF01965 DJ-1/PfpI family 3 168 4.0E-18 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UA74_24300 6e83d6d24f0dcba50cb7264974665ea3 311 SUPERFAMILY SSF46689 208 256 6.27E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_24300 6e83d6d24f0dcba50cb7264974665ea3 311 Pfam PF12833 Helix-turn-helix domain 229 307 9.6E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00412 Epoxide hydrolase signature 253 275 6.3E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00412 Epoxide hydrolase signature 31 49 6.3E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 6.3E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00412 Epoxide hydrolase signature 51 66 6.3E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 Gene3D G3DSA:3.40.50.1820 3 277 1.3E-89 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 6.5E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 6.5E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 6.5E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 Pfam PF00561 alpha/beta hydrolase fold 26 264 5.4E-32 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19325 9ca61f4f659d6e40e535c300ba49b1c6 278 SUPERFAMILY SSF53474 13 277 2.11E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15020 6e04c4a42d9847f08d5eea9a9e4af1b1 136 Gene3D G3DSA:1.10.10.10 15 134 8.1E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_15020 6e04c4a42d9847f08d5eea9a9e4af1b1 136 SUPERFAMILY SSF46785 20 122 6.0E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_15020 6e04c4a42d9847f08d5eea9a9e4af1b1 136 Pfam PF01638 HxlR-like helix-turn-helix 36 121 4.5E-24 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_30195 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.10.330.110 705 754 8.5E-193 T 12-10-2018 UA74_30195 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.40.50.620 57 174 2.1E-40 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_30195 63cb35602b81513ff8355665e13d2129 963 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 21 963 21.135 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_30195 63cb35602b81513ff8355665e13d2129 963 Pfam PF09334 tRNA synthetases class I (M) 65 167 5.0E-12 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_30195 63cb35602b81513ff8355665e13d2129 963 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 223 963 2.9E-210 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_30195 63cb35602b81513ff8355665e13d2129 963 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 298 501 1.1E-53 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 UA74_30195 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.90.740.10 312 525 8.5E-193 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_30195 63cb35602b81513ff8355665e13d2129 963 SUPERFAMILY SSF52374 26 780 2.53E-104 T 12-10-2018 UA74_30195 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 597 615 1.8E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_30195 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 682 692 1.8E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_30195 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 649 671 1.8E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_30195 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 170 1.8E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_30195 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 292 311 1.8E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_30195 63cb35602b81513ff8355665e13d2129 963 PRINTS PR00985 Leucyl-tRNA synthetase signature 263 276 1.8E-43 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UA74_30195 63cb35602b81513ff8355665e13d2129 963 SUPERFAMILY SSF47323 775 963 2.8E-33 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_30195 63cb35602b81513ff8355665e13d2129 963 SUPERFAMILY SSF50677 300 516 1.15E-41 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_30195 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:1.10.730.10 755 902 8.5E-193 T 12-10-2018 UA74_30195 63cb35602b81513ff8355665e13d2129 963 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 69 79 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_30195 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.10.20.590 903 963 7.8E-21 T 12-10-2018 UA74_30195 63cb35602b81513ff8355665e13d2129 963 Pfam PF08264 Anticodon-binding domain of tRNA 810 925 3.6E-16 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 UA74_30195 63cb35602b81513ff8355665e13d2129 963 Gene3D G3DSA:3.40.50.620 222 704 8.5E-193 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_29165 d6e9f7b2f03c06ce1ab75e109aa9a764 391 Gene3D G3DSA:3.30.1360.120 42 368 5.7E-66 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_29165 d6e9f7b2f03c06ce1ab75e109aa9a764 391 PIRSF PIRSF006487 37 375 2.4E-22 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UA74_29165 d6e9f7b2f03c06ce1ab75e109aa9a764 391 SUPERFAMILY SSF103025 40 294 5.02E-57 T 12-10-2018 UA74_29165 d6e9f7b2f03c06ce1ab75e109aa9a764 391 Pfam PF01571 Aminomethyltransferase folate-binding domain 40 268 1.9E-29 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain UA74_29165 d6e9f7b2f03c06ce1ab75e109aa9a764 391 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 240 304 2.9E-17 T 12-10-2018 IPR017703 YgfZ/GcvT conserved site UA74_29165 d6e9f7b2f03c06ce1ab75e109aa9a764 391 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 278 366 6.0E-8 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_09845 d49fb75ef8490646ebb1cfe197b96647 536 Gene3D G3DSA:3.40.190.10 64 511 9.6E-104 T 12-10-2018 UA74_09845 d49fb75ef8490646ebb1cfe197b96647 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 435 5.6E-65 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_09845 d49fb75ef8490646ebb1cfe197b96647 536 SUPERFAMILY SSF53850 38 532 3.98E-95 T 12-10-2018 UA74_09845 d49fb75ef8490646ebb1cfe197b96647 536 Gene3D G3DSA:3.10.105.10 279 497 9.6E-104 T 12-10-2018 UA74_09845 d49fb75ef8490646ebb1cfe197b96647 536 PIRSF PIRSF002741 4 528 2.6E-78 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_09845 d49fb75ef8490646ebb1cfe197b96647 536 Gene3D G3DSA:3.90.76.10 65 181 9.6E-104 T 12-10-2018 UA74_01740 af11e89931105413d76311205413c94f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 1.2E-36 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_01740 af11e89931105413d76311205413c94f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 1.2E-36 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_01740 af11e89931105413d76311205413c94f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 1.2E-36 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_01740 af11e89931105413d76311205413c94f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 1.2E-36 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_01740 af11e89931105413d76311205413c94f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 1.2E-36 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_01740 af11e89931105413d76311205413c94f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 1.2E-36 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_01740 af11e89931105413d76311205413c94f 258 Gene3D G3DSA:3.30.540.10 1 140 9.5E-36 T 12-10-2018 UA74_01740 af11e89931105413d76311205413c94f 258 Pfam PF00459 Inositol monophosphatase family 8 249 2.9E-52 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_01740 af11e89931105413d76311205413c94f 258 Gene3D G3DSA:3.40.190.80 141 256 7.9E-28 T 12-10-2018 UA74_01740 af11e89931105413d76311205413c94f 258 SUPERFAMILY SSF56655 6 252 5.1E-63 T 12-10-2018 UA74_01740 af11e89931105413d76311205413c94f 258 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 UA74_06240 ac59cd4f8840eaa3c1e55c3fec93a237 261 SUPERFAMILY SSF53681 111 258 1.26E-38 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_06240 ac59cd4f8840eaa3c1e55c3fec93a237 261 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_06240 ac59cd4f8840eaa3c1e55c3fec93a237 261 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_06240 ac59cd4f8840eaa3c1e55c3fec93a237 261 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 216 8.7E-32 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_06240 ac59cd4f8840eaa3c1e55c3fec93a237 261 Gene3D G3DSA:3.40.50.1860 7 257 1.5E-92 T 12-10-2018 UA74_06240 ac59cd4f8840eaa3c1e55c3fec93a237 261 SUPERFAMILY SSF53681 7 109 1.31E-32 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_06240 ac59cd4f8840eaa3c1e55c3fec93a237 261 Gene3D G3DSA:3.40.50.1860 97 208 1.5E-92 T 12-10-2018 UA74_06240 ac59cd4f8840eaa3c1e55c3fec93a237 261 Hamap MF_00258 Glutamate racemase [murI]. 6 259 36.156 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_06240 ac59cd4f8840eaa3c1e55c3fec93a237 261 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 255 3.5E-66 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UA74_18245 9929b344365e98af54196913ec5cbc3f 345 Gene3D G3DSA:3.40.50.2300 47 324 3.9E-66 T 12-10-2018 UA74_18245 9929b344365e98af54196913ec5cbc3f 345 SUPERFAMILY SSF53822 37 336 7.23E-56 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_18245 9929b344365e98af54196913ec5cbc3f 345 Gene3D G3DSA:3.40.50.2300 138 342 3.9E-66 T 12-10-2018 UA74_18245 9929b344365e98af54196913ec5cbc3f 345 Pfam PF13407 Periplasmic binding protein domain 39 299 3.2E-47 T 12-10-2018 IPR025997 Periplasmic binding protein UA74_01235 73413774acd58b9a3654ef078cddc551 273 SUPERFAMILY SSF56281 30 272 3.28E-49 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_01235 73413774acd58b9a3654ef078cddc551 273 Gene3D G3DSA:3.60.15.10 17 205 3.7E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_01235 73413774acd58b9a3654ef078cddc551 273 SMART SM00849 40 201 6.2E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_01235 73413774acd58b9a3654ef078cddc551 273 Gene3D G3DSA:1.10.10.10 209 273 1.5E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_01235 73413774acd58b9a3654ef078cddc551 273 Pfam PF00753 Metallo-beta-lactamase superfamily 39 201 4.1E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_24400 2443211dcf8f3cf857f33ab115a4a1be 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 8.4E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_24400 2443211dcf8f3cf857f33ab115a4a1be 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 104 119 8.4E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_24400 2443211dcf8f3cf857f33ab115a4a1be 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 87 8.4E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_24400 2443211dcf8f3cf857f33ab115a4a1be 147 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 89 104 8.4E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_24400 2443211dcf8f3cf857f33ab115a4a1be 147 SMART SM00418 55 133 3.2E-28 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_24400 2443211dcf8f3cf857f33ab115a4a1be 147 Gene3D G3DSA:1.10.10.10 41 144 1.2E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24400 2443211dcf8f3cf857f33ab115a4a1be 147 SUPERFAMILY SSF46785 45 128 4.12E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24400 2443211dcf8f3cf857f33ab115a4a1be 147 Pfam PF01022 Bacterial regulatory protein, arsR family 63 107 8.0E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_11630 a7bd18b2c2997ddebfd06ae0c455a8af 240 PIRSF PIRSF015736 3 239 2.6E-49 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase UA74_11630 a7bd18b2c2997ddebfd06ae0c455a8af 240 Gene3D G3DSA:3.40.50.12500 2 235 2.0E-52 T 12-10-2018 UA74_23530 bb43e96799848a6ed4d4ccd59e506d4f 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 111 178 1.1E-10 T 12-10-2018 IPR009597 Domain of unknown function DUF1206 UA74_23530 bb43e96799848a6ed4d4ccd59e506d4f 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 26 92 3.0E-19 T 12-10-2018 IPR009597 Domain of unknown function DUF1206 UA74_23530 bb43e96799848a6ed4d4ccd59e506d4f 274 Pfam PF06724 Domain of Unknown Function (DUF1206) 203 270 9.7E-16 T 12-10-2018 IPR009597 Domain of unknown function DUF1206 UA74_23435 49f654a79cf687c28f793b68a221abd8 99 Pfam PF02467 Transcription factor WhiB 17 87 7.2E-22 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain UA74_23435 49f654a79cf687c28f793b68a221abd8 99 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 18.508 T 12-10-2018 IPR003482 Transcription factor WhiB UA74_19180 1859ed11780c01ffd0e3832bf4aed647 306 Pfam PF13732 Domain of unknown function (DUF4162) 228 300 8.0E-7 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 UA74_19180 1859ed11780c01ffd0e3832bf4aed647 306 Gene3D G3DSA:3.40.50.300 9 239 7.2E-55 T 12-10-2018 UA74_19180 1859ed11780c01ffd0e3832bf4aed647 306 Pfam PF00005 ABC transporter 32 169 1.1E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_19180 1859ed11780c01ffd0e3832bf4aed647 306 SUPERFAMILY SSF52540 15 228 3.52E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19180 1859ed11780c01ffd0e3832bf4aed647 306 SMART SM00382 40 225 9.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_26770 3312ab62edee774d31773b5f94e05c56 174 Gene3D G3DSA:3.40.50.7700 1 173 1.9E-70 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 UA74_26770 3312ab62edee774d31773b5f94e05c56 174 SUPERFAMILY SSF52255 7 156 3.79E-62 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 UA74_26770 3312ab62edee774d31773b5f94e05c56 174 Pfam PF00731 AIR carboxylase 9 150 5.5E-63 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UA74_26770 3312ab62edee774d31773b5f94e05c56 174 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 9 160 31.09 T 12-10-2018 IPR033747 Class I PurE UA74_26770 3312ab62edee774d31773b5f94e05c56 174 PIRSF PIRSF001338 4 171 7.2E-65 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 UA74_26770 3312ab62edee774d31773b5f94e05c56 174 SMART SM01001 7 156 4.0E-88 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UA74_26770 3312ab62edee774d31773b5f94e05c56 174 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 9 156 6.7E-62 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UA74_18745 464f83dfdf770e0571ff170a72c63307 413 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 197 373 3.1E-44 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_18745 464f83dfdf770e0571ff170a72c63307 413 SUPERFAMILY SSF51735 190 373 2.96E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18745 464f83dfdf770e0571ff170a72c63307 413 SUPERFAMILY SSF52283 130 219 4.13E-9 T 12-10-2018 UA74_18745 464f83dfdf770e0571ff170a72c63307 413 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 141 404 2.5E-7 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UA74_18745 464f83dfdf770e0571ff170a72c63307 413 Gene3D G3DSA:3.40.50.720 186 372 1.2E-77 T 12-10-2018 UA74_18745 464f83dfdf770e0571ff170a72c63307 413 Gene3D G3DSA:3.40.50.720 123 395 1.2E-77 T 12-10-2018 UA74_07510 b3424fdf3c0248a7cafaf198ad1f56f5 662 Gene3D G3DSA:3.20.20.80 196 566 1.0E-163 T 12-10-2018 UA74_07510 b3424fdf3c0248a7cafaf198ad1f56f5 662 SMART SM00642 201 536 2.2E-5 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07510 b3424fdf3c0248a7cafaf198ad1f56f5 662 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 3 661 44.804 T 12-10-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 UA74_07510 b3424fdf3c0248a7cafaf198ad1f56f5 662 Gene3D G3DSA:2.60.40.1180 567 662 8.3E-31 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_07510 b3424fdf3c0248a7cafaf198ad1f56f5 662 Gene3D G3DSA:1.20.58.280 95 176 1.0E-56 T 12-10-2018 UA74_07510 b3424fdf3c0248a7cafaf198ad1f56f5 662 SUPERFAMILY SSF51445 201 561 1.72E-81 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07510 b3424fdf3c0248a7cafaf198ad1f56f5 662 Gene3D G3DSA:2.60.40.10 6 195 1.0E-56 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_07510 b3424fdf3c0248a7cafaf198ad1f56f5 662 Pfam PF11896 Domain of unknown function (DUF3416) 5 195 4.7E-58 T 12-10-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 UA74_07510 b3424fdf3c0248a7cafaf198ad1f56f5 662 Pfam PF00128 Alpha amylase, catalytic domain 223 328 9.9E-5 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_17510 25a6c4403f15815b24be386542737e25 348 SUPERFAMILY SSF53335 120 342 2.71E-35 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_17510 25a6c4403f15815b24be386542737e25 348 Gene3D G3DSA:1.20.58.1390 107 309 1.1E-63 T 12-10-2018 UA74_17510 25a6c4403f15815b24be386542737e25 348 Gene3D G3DSA:3.40.50.150 164 344 1.1E-63 T 12-10-2018 UA74_17510 25a6c4403f15815b24be386542737e25 348 SUPERFAMILY SSF46785 13 87 7.71E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_17510 25a6c4403f15815b24be386542737e25 348 Gene3D G3DSA:1.10.10.10 11 88 1.4E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17510 25a6c4403f15815b24be386542737e25 348 Pfam PF00891 O-methyltransferase 137 332 6.1E-29 T 12-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_17510 25a6c4403f15815b24be386542737e25 348 PIRSF PIRSF005739 3 348 2.2E-23 T 12-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_17510 25a6c4403f15815b24be386542737e25 348 Pfam PF16864 Dimerisation domain 18 97 6.8E-8 T 12-10-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain UA74_27910 915c0af67299669116c47fa2fa56aff7 538 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 525 1.6E-224 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_27910 915c0af67299669116c47fa2fa56aff7 538 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 521 2.2E-82 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 UA74_27910 915c0af67299669116c47fa2fa56aff7 538 Gene3D G3DSA:3.50.7.10 191 371 2.4E-209 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily UA74_27910 915c0af67299669116c47fa2fa56aff7 538 Hamap MF_00600 60 kDa chaperonin [groL]. 2 538 38.816 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_27910 915c0af67299669116c47fa2fa56aff7 538 Gene3D G3DSA:3.30.260.10 136 409 2.4E-209 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily UA74_27910 915c0af67299669116c47fa2fa56aff7 538 ProSitePatterns PS00296 Chaperonins cpn60 signature. 404 415 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_27910 915c0af67299669116c47fa2fa56aff7 538 Gene3D G3DSA:1.10.560.10 8 520 2.4E-209 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily UA74_27910 915c0af67299669116c47fa2fa56aff7 538 SUPERFAMILY SSF54849 137 203 3.66E-18 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily UA74_27910 915c0af67299669116c47fa2fa56aff7 538 SUPERFAMILY SSF52029 184 375 7.33E-74 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily UA74_27910 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 27 53 9.0E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_27910 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 267 290 9.0E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_27910 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 349 374 9.0E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_27910 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 397 418 9.0E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_27910 915c0af67299669116c47fa2fa56aff7 538 PRINTS PR00298 60kDa chaperonin signature 83 110 9.0E-67 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_27910 915c0af67299669116c47fa2fa56aff7 538 SUPERFAMILY SSF48592 3 522 4.95E-71 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily UA74_27230 c85b1f64bd7d2b02b24d28fe96931e42 132 Gene3D G3DSA:1.10.1660.10 1 130 1.3E-29 T 12-10-2018 UA74_27230 c85b1f64bd7d2b02b24d28fe96931e42 132 Pfam PF13411 MerR HTH family regulatory protein 3 68 6.2E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_27230 c85b1f64bd7d2b02b24d28fe96931e42 132 SUPERFAMILY SSF46955 3 117 1.28E-29 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_27230 c85b1f64bd7d2b02b24d28fe96931e42 132 SMART SM00422 3 72 2.6E-21 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_27230 c85b1f64bd7d2b02b24d28fe96931e42 132 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_27230 c85b1f64bd7d2b02b24d28fe96931e42 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 3.9E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_27230 c85b1f64bd7d2b02b24d28fe96931e42 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 3.9E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_27230 c85b1f64bd7d2b02b24d28fe96931e42 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 3.9E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_10025 06197d6db6e46b2cc731a7e0661d40c1 211 SUPERFAMILY SSF48498 96 202 1.51E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_10025 06197d6db6e46b2cc731a7e0661d40c1 211 Gene3D G3DSA:1.10.10.60 13 76 5.1E-21 T 12-10-2018 UA74_10025 06197d6db6e46b2cc731a7e0661d40c1 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 75 2.4E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_10025 06197d6db6e46b2cc731a7e0661d40c1 211 Gene3D G3DSA:1.10.357.10 77 203 2.4E-32 T 12-10-2018 UA74_10025 06197d6db6e46b2cc731a7e0661d40c1 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 9.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_10025 06197d6db6e46b2cc731a7e0661d40c1 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 9.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_10025 06197d6db6e46b2cc731a7e0661d40c1 211 SUPERFAMILY SSF46689 16 82 1.03E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_09615 26cf9457e48cf619c7af18aae6caaef2 614 Gene3D G3DSA:3.90.1310.30 69 256 2.9E-27 T 12-10-2018 UA74_09615 26cf9457e48cf619c7af18aae6caaef2 614 Gene3D G3DSA:3.40.710.10 318 509 2.4E-100 T 12-10-2018 UA74_09615 26cf9457e48cf619c7af18aae6caaef2 614 SUPERFAMILY SSF56601 257 599 1.26E-89 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_09615 26cf9457e48cf619c7af18aae6caaef2 614 Gene3D G3DSA:3.30.450.330 258 593 2.4E-100 T 12-10-2018 UA74_09615 26cf9457e48cf619c7af18aae6caaef2 614 Pfam PF00905 Penicillin binding protein transpeptidase domain 282 588 2.5E-82 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_09615 26cf9457e48cf619c7af18aae6caaef2 614 Pfam PF03717 Penicillin-binding Protein dimerisation domain 76 216 7.7E-9 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UA74_09615 26cf9457e48cf619c7af18aae6caaef2 614 SUPERFAMILY SSF56519 74 256 4.19E-27 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 UA74_05895 d6f80f9c634e2c5ed07969293323c286 669 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 503 662 2.7E-14 T 12-10-2018 UA74_05895 d6f80f9c634e2c5ed07969293323c286 669 Gene3D G3DSA:2.60.120.200 431 665 5.6E-17 T 12-10-2018 UA74_05895 d6f80f9c634e2c5ed07969293323c286 669 Pfam PF00149 Calcineurin-like phosphoesterase 97 263 9.6E-7 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UA74_05895 d6f80f9c634e2c5ed07969293323c286 669 SUPERFAMILY SSF56300 97 333 1.94E-21 T 12-10-2018 UA74_05895 d6f80f9c634e2c5ed07969293323c286 669 Gene3D G3DSA:3.60.21.10 81 310 5.1E-12 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_05895 d6f80f9c634e2c5ed07969293323c286 669 SUPERFAMILY SSF49899 407 662 3.08E-22 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UA74_07365 479e1344a52ed9108174e62681caba98 102 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 35 92 4.7E-7 T 12-10-2018 IPR026496 Putative ATP-grasp target RiPP UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 Pfam PF00717 Peptidase S24-like 160 223 1.6E-15 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 Gene3D G3DSA:1.10.10.10 33 98 2.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 TIGRFAM TIGR00498 lexA: repressor LexA 32 240 4.7E-76 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 Pfam PF01726 LexA DNA binding domain 32 95 4.2E-28 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 Gene3D G3DSA:2.10.109.10 126 241 5.4E-42 T 12-10-2018 UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 SUPERFAMILY SSF46785 33 99 1.23E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 SUPERFAMILY SSF51306 120 239 4.88E-36 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 Hamap MF_00015 LexA repressor [lexA]. 33 241 33.936 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 168 179 2.1E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 196 208 2.1E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 UA74_08635 42764bfcac4fc90c86247cd524e94e3a 241 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 157 167 2.1E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 UA74_27925 861b80a5b762aaba44fef7904ab9414d 317 SUPERFAMILY SSF56059 131 313 6.42E-11 T 12-10-2018 UA74_27925 861b80a5b762aaba44fef7904ab9414d 317 Gene3D G3DSA:3.30.470.20 206 315 9.1E-13 T 12-10-2018 UA74_27925 861b80a5b762aaba44fef7904ab9414d 317 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 312 6.5E-110 T 12-10-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV-5884 family UA74_20035 1dece367f47650b48da212dea10e15d7 317 Gene3D G3DSA:1.10.3720.10 71 312 6.1E-63 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20035 1dece367f47650b48da212dea10e15d7 317 SUPERFAMILY SSF161098 75 302 7.06E-57 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20035 1dece367f47650b48da212dea10e15d7 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 303 4.3E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_26080 7d5c26b6f463cc8ebc83074ba9850fe5 171 Pfam PF00583 Acetyltransferase (GNAT) family 50 145 1.9E-14 T 12-10-2018 IPR000182 GNAT domain UA74_26080 7d5c26b6f463cc8ebc83074ba9850fe5 171 SUPERFAMILY SSF55729 10 150 1.36E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_26080 7d5c26b6f463cc8ebc83074ba9850fe5 171 Gene3D G3DSA:3.40.630.30 2 152 8.2E-27 T 12-10-2018 UA74_23015 c9d03a3fddf826c0c62cf5c58260d245 352 Gene3D G3DSA:1.10.10.10 24 113 1.4E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23015 c9d03a3fddf826c0c62cf5c58260d245 352 SUPERFAMILY SSF46785 27 114 9.07E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_23015 c9d03a3fddf826c0c62cf5c58260d245 352 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 29 94 7.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_01245 9e86ec99f8711264160efe5cb9eddc69 439 PRINTS PR01035 Tetracycline resistance protein signature 258 277 1.0E-4 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_01245 9e86ec99f8711264160efe5cb9eddc69 439 PRINTS PR01035 Tetracycline resistance protein signature 347 369 1.0E-4 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_01245 9e86ec99f8711264160efe5cb9eddc69 439 PRINTS PR01035 Tetracycline resistance protein signature 229 245 1.0E-4 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_01245 9e86ec99f8711264160efe5cb9eddc69 439 Gene3D G3DSA:1.20.1250.20 22 399 6.0E-20 T 12-10-2018 UA74_01245 9e86ec99f8711264160efe5cb9eddc69 439 SUPERFAMILY SSF103473 24 404 1.96E-26 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_01245 9e86ec99f8711264160efe5cb9eddc69 439 Pfam PF07690 Major Facilitator Superfamily 27 337 4.5E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_10275 201cbf07fc83366486a7b8c927884373 273 SUPERFAMILY SSF81301 14 130 8.18E-7 T 12-10-2018 UA74_10275 201cbf07fc83366486a7b8c927884373 273 Gene3D G3DSA:1.20.120.330 144 272 1.5E-33 T 12-10-2018 UA74_10275 201cbf07fc83366486a7b8c927884373 273 Gene3D G3DSA:3.30.460.10 9 142 6.4E-30 T 12-10-2018 UA74_13870 5304e025463e4112da97209d6eb8d146 292 SUPERFAMILY SSF161098 83 266 5.89E-34 T 12-10-2018 IPR035906 MetI-like superfamily UA74_13870 5304e025463e4112da97209d6eb8d146 292 Gene3D G3DSA:1.10.3720.10 80 274 8.2E-29 T 12-10-2018 IPR035906 MetI-like superfamily UA74_13870 5304e025463e4112da97209d6eb8d146 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 269 4.4E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_18555 619a086a5e47d040d9a4298704ae1c24 446 Gene3D G3DSA:3.40.462.20 205 403 4.8E-88 T 12-10-2018 UA74_18555 619a086a5e47d040d9a4298704ae1c24 446 Pfam PF01565 FAD binding domain 38 173 5.9E-30 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_18555 619a086a5e47d040d9a4298704ae1c24 446 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 38 71 - T 12-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 UA74_18555 619a086a5e47d040d9a4298704ae1c24 446 Gene3D G3DSA:3.30.465.10 106 431 4.8E-88 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_18555 619a086a5e47d040d9a4298704ae1c24 446 SUPERFAMILY SSF56176 5 200 4.46E-46 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_18555 619a086a5e47d040d9a4298704ae1c24 446 Gene3D G3DSA:3.30.43.10 15 90 2.9E-25 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 UA74_07800 e38d44b2a7461e7393cac479b7c26aa8 203 Gene3D G3DSA:3.40.50.720 11 149 3.2E-17 T 12-10-2018 UA74_07800 e38d44b2a7461e7393cac479b7c26aa8 203 SUPERFAMILY SSF51735 8 123 6.83E-17 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_06885 2a4790e3ca408ce965e502cc99236eb5 334 Gene3D G3DSA:1.40.20.10 8 333 1.0E-49 T 12-10-2018 IPR038186 CHAD domain superfamily UA74_06885 2a4790e3ca408ce965e502cc99236eb5 334 SMART SM00880 28 315 2.8E-54 T 12-10-2018 IPR007899 CHAD domain UA74_06885 2a4790e3ca408ce965e502cc99236eb5 334 Pfam PF05235 CHAD domain 28 283 1.7E-48 T 12-10-2018 IPR007899 CHAD domain UA74_00455 ce2a17b191c4fc9dc94c7347cf3c5b99 147 SUPERFAMILY SSF54427 20 146 3.39E-31 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_00455 ce2a17b191c4fc9dc94c7347cf3c5b99 147 Pfam PF14534 Domain of unknown function (DUF4440) 25 136 4.6E-9 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 UA74_00455 ce2a17b191c4fc9dc94c7347cf3c5b99 147 Gene3D G3DSA:3.10.450.50 10 146 8.8E-32 T 12-10-2018 UA74_00455 ce2a17b191c4fc9dc94c7347cf3c5b99 147 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 21 146 2.1E-19 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Gene3D G3DSA:3.30.10.20 511 574 5.1E-12 T 12-10-2018 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 SUPERFAMILY SSF56112 8 276 1.31E-76 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF00069 Protein kinase domain 11 265 6.2E-50 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Gene3D G3DSA:3.30.200.20 1 94 4.3E-35 T 12-10-2018 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Gene3D G3DSA:3.30.10.20 372 441 4.8E-17 T 12-10-2018 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Gene3D G3DSA:1.10.510.10 96 283 8.7E-56 T 12-10-2018 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00740 371 439 2.2E-13 T 12-10-2018 IPR005543 PASTA domain UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00740 440 509 5.9E-7 T 12-10-2018 IPR005543 PASTA domain UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00740 576 644 0.019 T 12-10-2018 IPR005543 PASTA domain UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00740 510 575 2.5E-12 T 12-10-2018 IPR005543 PASTA domain UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Gene3D G3DSA:3.30.10.20 442 508 5.8E-11 T 12-10-2018 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Gene3D G3DSA:3.30.10.20 575 644 1.1E-9 T 12-10-2018 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 SMART SM00220 11 274 1.7E-64 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF03793 PASTA domain 515 574 4.4E-10 T 12-10-2018 IPR005543 PASTA domain UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF03793 PASTA domain 445 507 8.8E-10 T 12-10-2018 IPR005543 PASTA domain UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF03793 PASTA domain 579 642 1.5E-5 T 12-10-2018 IPR005543 PASTA domain UA74_00130 1a5240f0bb502b044ff1db53dcec4a66 655 Pfam PF03793 PASTA domain 375 437 1.5E-14 T 12-10-2018 IPR005543 PASTA domain UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 Gene3D G3DSA:3.40.50.300 1035 1197 1.7E-42 T 12-10-2018 UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 Gene3D G3DSA:3.30.70.1620 572 652 3.4E-19 T 12-10-2018 UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 SMART SM00968 512 625 9.4E-17 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1188 1.1E-279 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 Gene3D G3DSA:1.20.1060.20 500 653 3.4E-19 T 12-10-2018 UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1190 22.113 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 624 3.1E-17 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1181 3.4E-71 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 SUPERFAMILY SSF52540 2 1183 2.03E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 SUPERFAMILY SSF75553 465 669 2.09E-25 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 Gene3D G3DSA:3.40.50.300 1 230 1.1E-55 T 12-10-2018 UA74_25530 a4eaad29796804cd5e24bf29a1ad926e 1274 PIRSF PIRSF005719 1 1195 2.0E-249 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein UA74_06375 cea1eccb3a07d43b9f4647b84a941e86 309 SUPERFAMILY SSF51161 30 215 2.11E-29 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily UA74_06375 cea1eccb3a07d43b9f4647b84a941e86 309 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 159 193 5.7E-7 T 12-10-2018 IPR001451 Hexapeptide repeat UA74_06375 cea1eccb3a07d43b9f4647b84a941e86 309 Gene3D G3DSA:2.160.10.10 55 225 8.3E-31 T 12-10-2018 UA74_26675 6eb93e71a24a686ac1294a18b711ea72 364 Gene3D G3DSA:3.40.50.2000 181 343 2.3E-49 T 12-10-2018 UA74_26675 6eb93e71a24a686ac1294a18b711ea72 364 Pfam PF13692 Glycosyl transferases group 1 205 327 6.5E-20 T 12-10-2018 UA74_26675 6eb93e71a24a686ac1294a18b711ea72 364 Pfam PF13439 Glycosyltransferase Family 4 25 184 1.3E-11 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_26675 6eb93e71a24a686ac1294a18b711ea72 364 SUPERFAMILY SSF53756 22 363 1.32E-59 T 12-10-2018 UA74_26675 6eb93e71a24a686ac1294a18b711ea72 364 Gene3D G3DSA:3.40.50.2000 25 359 2.3E-49 T 12-10-2018 UA74_08865 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 Gene3D G3DSA:1.10.10.10 3 77 1.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08865 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 ProSitePatterns PS01125 ROK family signature. 216 243 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_08865 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 Gene3D G3DSA:3.30.420.40 93 389 1.2E-81 T 12-10-2018 UA74_08865 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 Gene3D G3DSA:3.30.420.40 206 379 1.2E-81 T 12-10-2018 UA74_08865 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 SUPERFAMILY SSF46785 12 74 6.21E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_08865 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 SUPERFAMILY SSF53067 82 394 1.03E-48 T 12-10-2018 UA74_08865 b57b4c8ce253c85dddcfc6dbfcdd8d86 410 Pfam PF00480 ROK family 85 393 1.8E-50 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 339 430 2.0E-14 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 440 462 1.7E-23 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 203 212 1.7E-23 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 114 131 1.7E-23 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 357 375 1.7E-23 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 SUPERFAMILY SSF50621 309 473 2.93E-45 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 96 114 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site UA74_06965 7581fa930c7f78deccc91e51c1202235 474 Gene3D G3DSA:2.40.37.10 54 469 2.7E-161 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 270 287 - T 12-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site UA74_06965 7581fa930c7f78deccc91e51c1202235 474 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 75 334 1.9E-60 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 55 473 37.718 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 231 244 7.4E-16 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 116 128 7.4E-16 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 430 443 7.4E-16 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 96 114 7.4E-16 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 324 343 7.4E-16 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UA74_06965 7581fa930c7f78deccc91e51c1202235 474 Gene3D G3DSA:3.20.20.10 74 334 2.7E-161 T 12-10-2018 IPR029066 PLP-binding barrel UA74_06965 7581fa930c7f78deccc91e51c1202235 474 SUPERFAMILY SSF51419 66 335 4.8E-71 T 12-10-2018 IPR029066 PLP-binding barrel UA74_06965 7581fa930c7f78deccc91e51c1202235 474 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 47 473 7.4E-139 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UA74_05565 b04e62105538b0f14f7e363e6df1c462 509 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 19 437 2.3E-146 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane UA74_23410 b2498f8bf21494d497dac5fea60d3a40 199 Pfam PF00583 Acetyltransferase (GNAT) family 109 175 1.1E-9 T 12-10-2018 IPR000182 GNAT domain UA74_23410 b2498f8bf21494d497dac5fea60d3a40 199 Gene3D G3DSA:3.40.630.30 3 198 9.0E-49 T 12-10-2018 UA74_23410 b2498f8bf21494d497dac5fea60d3a40 199 SUPERFAMILY SSF55729 7 193 8.86E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_29895 6c5dad5826643c03cac559101148bb30 309 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 87 182 3.2E-17 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UA74_29895 6c5dad5826643c03cac559101148bb30 309 Gene3D G3DSA:1.10.3720.10 74 294 1.4E-45 T 12-10-2018 IPR035906 MetI-like superfamily UA74_29895 6c5dad5826643c03cac559101148bb30 309 SUPERFAMILY SSF161098 86 276 1.07E-38 T 12-10-2018 IPR035906 MetI-like superfamily UA74_29895 6c5dad5826643c03cac559101148bb30 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 290 1.3E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 SUPERFAMILY SSF56784 339 631 4.51E-47 T 12-10-2018 IPR036412 HAD-like superfamily UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 Pfam PF00122 E1-E2 ATPase 143 320 1.7E-42 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00941 Cadmium-transporting ATPase signature 208 224 4.3E-6 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00941 Cadmium-transporting ATPase signature 227 241 4.3E-6 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00941 Cadmium-transporting ATPase signature 127 147 4.3E-6 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00941 Cadmium-transporting ATPase signature 147 163 4.3E-6 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 93 633 2.6E-167 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 Pfam PF00702 haloacid dehalogenase-like hydrolase 337 545 2.0E-40 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 SUPERFAMILY SSF81665 95 335 1.27E-12 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 Gene3D G3DSA:2.70.150.20 142 247 2.8E-29 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 118 610 5.2E-75 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 Gene3D G3DSA:3.40.50.1000 322 583 1.1E-80 T 12-10-2018 IPR023214 HAD superfamily UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 192 206 5.5E-26 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 341 355 5.5E-26 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 531 550 5.5E-26 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 468 5.5E-26 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 479 489 5.5E-26 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 5.5E-26 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 Gene3D G3DSA:3.40.1110.10 352 464 1.1E-80 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 92 635 4.7E-148 T 12-10-2018 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 SUPERFAMILY SSF81653 145 242 6.15E-21 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 UA74_16920 ce63f0e7791a309804677b6b3c335bea 670 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 343 349 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_14935 88e4abce12746dab8397735225842d76 573 Gene3D G3DSA:1.20.140.10 306 461 1.5E-33 T 12-10-2018 UA74_14935 88e4abce12746dab8397735225842d76 573 SUPERFAMILY SSF47203 310 462 2.26E-37 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_14935 88e4abce12746dab8397735225842d76 573 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 305 459 2.7E-28 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_14935 88e4abce12746dab8397735225842d76 573 Gene3D G3DSA:2.40.110.20 150 305 1.1E-56 T 12-10-2018 UA74_14935 88e4abce12746dab8397735225842d76 573 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 418 437 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_14935 88e4abce12746dab8397735225842d76 573 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 200 295 8.3E-15 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UA74_14935 88e4abce12746dab8397735225842d76 573 SUPERFAMILY SSF56645 78 314 1.97E-36 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_19515 5b4d4acd8fca7e8c163a0815203b54bd 330 Gene3D G3DSA:3.90.180.10 102 313 6.8E-34 T 12-10-2018 UA74_19515 5b4d4acd8fca7e8c163a0815203b54bd 330 Gene3D G3DSA:3.90.180.10 11 99 2.6E-12 T 12-10-2018 UA74_19515 5b4d4acd8fca7e8c163a0815203b54bd 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 106 5.1E-6 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_19515 5b4d4acd8fca7e8c163a0815203b54bd 330 SUPERFAMILY SSF50129 9 161 5.17E-15 T 12-10-2018 IPR011032 GroES-like superfamily UA74_19515 5b4d4acd8fca7e8c163a0815203b54bd 330 Gene3D G3DSA:3.40.50.720 139 272 6.8E-34 T 12-10-2018 UA74_19515 5b4d4acd8fca7e8c163a0815203b54bd 330 SUPERFAMILY SSF51735 133 288 5.97E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_19515 5b4d4acd8fca7e8c163a0815203b54bd 330 Pfam PF16912 Glucose dehydrogenase C-terminus 145 313 7.3E-13 T 12-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 UA74_18740 1f8db5a7dec9e5dd3f224090d5588964 346 SMART SM01130 15 329 2.1E-9 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_18740 1f8db5a7dec9e5dd3f224090d5588964 346 Pfam PF00701 Dihydrodipicolinate synthetase family 22 226 2.1E-6 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_18740 1f8db5a7dec9e5dd3f224090d5588964 346 SUPERFAMILY SSF51569 19 326 1.26E-30 T 12-10-2018 UA74_18740 1f8db5a7dec9e5dd3f224090d5588964 346 Gene3D G3DSA:3.20.20.70 9 328 8.2E-24 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_24890 f086e7d4e183a22d5a594c579d7707b7 629 Pfam PF05991 YacP-like NYN domain 509 626 1.8E-19 T 12-10-2018 IPR010298 Protein of unknown function DUF901 UA74_03225 059775fa1da099c066753116943a63a5 471 Gene3D G3DSA:3.30.565.10 321 470 2.5E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_03225 059775fa1da099c066753116943a63a5 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 467 3.0E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_03225 059775fa1da099c066753116943a63a5 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 318 1.3E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_03225 059775fa1da099c066753116943a63a5 471 Gene3D G3DSA:1.10.287.130 198 319 1.2E-26 T 12-10-2018 UA74_03225 059775fa1da099c066753116943a63a5 471 SUPERFAMILY SSF55874 321 468 2.1E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_03225 059775fa1da099c066753116943a63a5 471 SMART SM00304 194 246 4.1E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_03225 059775fa1da099c066753116943a63a5 471 SMART SM00388 247 319 7.9E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_03225 059775fa1da099c066753116943a63a5 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_03225 059775fa1da099c066753116943a63a5 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 425 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_03225 059775fa1da099c066753116943a63a5 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_03225 059775fa1da099c066753116943a63a5 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_03225 059775fa1da099c066753116943a63a5 471 SUPERFAMILY SSF47384 230 320 1.33E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_03225 059775fa1da099c066753116943a63a5 471 Pfam PF00672 HAMP domain 194 239 1.0E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_03225 059775fa1da099c066753116943a63a5 471 SUPERFAMILY SSF158472 194 242 1.44E-5 T 12-10-2018 UA74_03225 059775fa1da099c066753116943a63a5 471 SMART SM00387 359 470 7.1E-34 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_07975 78140ca499c243781a52d1b7928693a2 157 SUPERFAMILY SSF89623 2 151 1.19E-48 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_07975 78140ca499c243781a52d1b7928693a2 157 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 1.1E-51 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_07975 78140ca499c243781a52d1b7928693a2 157 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 3.0E-65 T 12-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 UA74_07975 78140ca499c243781a52d1b7928693a2 157 PIRSF PIRSF005384 1 149 7.8E-46 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_07975 78140ca499c243781a52d1b7928693a2 157 Pfam PF02502 Ribose/Galactose Isomerase 3 140 4.1E-43 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_07975 78140ca499c243781a52d1b7928693a2 157 Gene3D G3DSA:3.40.1400.10 1 156 1.2E-53 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 Gene3D G3DSA:3.90.1660.10 69 251 3.9E-67 T 12-10-2018 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 21 251 3.9E-77 T 12-10-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 Pfam PF00881 Nitroreductase family 269 437 1.9E-24 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 Pfam PF01996 F420-0:Gamma-glutamyl ligase 85 228 1.1E-32 T 12-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 Pfam PF01996 F420-0:Gamma-glutamyl ligase 29 74 1.5E-6 T 12-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 Gene3D G3DSA:3.40.109.10 253 455 4.2E-49 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 SUPERFAMILY SSF144010 22 255 5.36E-64 T 12-10-2018 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 264 456 4.2E-93 T 12-10-2018 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 SUPERFAMILY SSF55469 263 456 8.25E-36 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 26 458 49.668 T 12-10-2018 IPR023661 Coenzyme F420:L-glutamate ligase, Actinobacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_26615 e0a3d47f9c17c6162274383101772e8e 458 Gene3D G3DSA:3.30.1330.100 25 236 3.9E-67 T 12-10-2018 UA74_08320 178c1da6bad9a0f41e05f1cb1eee1d67 80 SUPERFAMILY SSF47598 4 49 7.78E-9 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 UA74_08320 178c1da6bad9a0f41e05f1cb1eee1d67 80 Gene3D G3DSA:1.10.1220.10 1 49 8.0E-7 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 UA74_25345 38d6de5b6002d6bc433ae95127c4290c 930 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 29 920 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 UA74_25345 38d6de5b6002d6bc433ae95127c4290c 930 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 159 323 2.1E-9 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_25345 38d6de5b6002d6bc433ae95127c4290c 930 SUPERFAMILY SSF52518 502 735 1.38E-84 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_25345 38d6de5b6002d6bc433ae95127c4290c 930 SUPERFAMILY SSF52922 738 916 7.15E-48 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_25345 38d6de5b6002d6bc433ae95127c4290c 930 Gene3D G3DSA:3.40.50.970 501 740 5.1E-100 T 12-10-2018 UA74_25345 38d6de5b6002d6bc433ae95127c4290c 930 PIRSF PIRSF000156 19 924 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 UA74_25345 38d6de5b6002d6bc433ae95127c4290c 930 SUPERFAMILY SSF52518 79 495 1.29E-129 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_25345 38d6de5b6002d6bc433ae95127c4290c 930 Gene3D G3DSA:3.40.50.920 743 923 4.0E-58 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_25345 38d6de5b6002d6bc433ae95127c4290c 930 Gene3D G3DSA:3.40.50.970 78 500 2.7E-131 T 12-10-2018 UA74_15675 7681fdcb0baa86106f99d8a2801603f2 613 SUPERFAMILY SSF52540 1 350 1.78E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15675 7681fdcb0baa86106f99d8a2801603f2 613 Gene3D G3DSA:3.40.50.300 165 357 1.3E-7 T 12-10-2018 UA74_15675 7681fdcb0baa86106f99d8a2801603f2 613 Gene3D G3DSA:3.40.50.300 1 80 2.9E-11 T 12-10-2018 UA74_15675 7681fdcb0baa86106f99d8a2801603f2 613 Pfam PF13175 AAA ATPase domain 1 46 1.9E-11 T 12-10-2018 UA74_15675 7681fdcb0baa86106f99d8a2801603f2 613 Pfam PF13175 AAA ATPase domain 229 337 1.6E-15 T 12-10-2018 UA74_27080 e189814679ca27f8070677402c9d403a 1687 SMART SM00089 796 882 7.7E-17 T 12-10-2018 IPR022409 PKD/Chitinase domain UA74_27080 e189814679ca27f8070677402c9d403a 1687 Pfam PF06439 Domain of Unknown Function (DUF1080) 1142 1320 5.0E-36 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 UA74_27080 e189814679ca27f8070677402c9d403a 1687 SUPERFAMILY SSF49299 794 881 4.45E-16 T 12-10-2018 IPR035986 PKD domain superfamily UA74_27080 e189814679ca27f8070677402c9d403a 1687 Gene3D G3DSA:2.60.120.260 990 1117 4.0E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_27080 e189814679ca27f8070677402c9d403a 1687 Gene3D G3DSA:2.120.10.30 334 797 1.6E-68 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_27080 e189814679ca27f8070677402c9d403a 1687 SMART SM00606 986 1118 9.1E-28 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 UA74_27080 e189814679ca27f8070677402c9d403a 1687 Pfam PF00801 PKD domain 810 870 2.8E-10 T 12-10-2018 IPR000601 PKD domain UA74_27080 e189814679ca27f8070677402c9d403a 1687 Pfam PF07995 Glucose / Sorbosone dehydrogenase 357 629 1.1E-32 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase UA74_27080 e189814679ca27f8070677402c9d403a 1687 Pfam PF06283 Trehalose utilisation 105 314 4.8E-85 T 12-10-2018 IPR029010 ThuA-like domain UA74_27080 e189814679ca27f8070677402c9d403a 1687 SUPERFAMILY SSF50952 339 774 2.22E-21 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_27080 e189814679ca27f8070677402c9d403a 1687 Pfam PF03422 Carbohydrate binding module (family 6) 994 1117 4.4E-26 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_27080 e189814679ca27f8070677402c9d403a 1687 SUPERFAMILY SSF52317 103 320 4.35E-47 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_27080 e189814679ca27f8070677402c9d403a 1687 Gene3D G3DSA:3.40.50.880 91 324 2.7E-91 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_27080 e189814679ca27f8070677402c9d403a 1687 Gene3D G3DSA:2.60.40.10 798 879 1.5E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_27080 e189814679ca27f8070677402c9d403a 1687 SUPERFAMILY SSF49785 993 1118 3.74E-23 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_27080 e189814679ca27f8070677402c9d403a 1687 Gene3D G3DSA:2.60.120.560 1136 1322 6.9E-39 T 12-10-2018 UA74_14450 c75f8f55d0d2d1400e2caeebd3728f2e 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 1.0E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14450 c75f8f55d0d2d1400e2caeebd3728f2e 213 Gene3D G3DSA:1.10.357.10 11 213 1.0E-42 T 12-10-2018 UA74_14450 c75f8f55d0d2d1400e2caeebd3728f2e 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 9.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14450 c75f8f55d0d2d1400e2caeebd3728f2e 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 9.2E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14450 c75f8f55d0d2d1400e2caeebd3728f2e 213 SUPERFAMILY SSF46689 16 88 2.29E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14450 c75f8f55d0d2d1400e2caeebd3728f2e 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 64 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_01335 1078c1db7d3307518219b193f55771d1 312 Gene3D G3DSA:3.40.50.10490 12 227 5.5E-69 T 12-10-2018 UA74_01335 1078c1db7d3307518219b193f55771d1 312 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 194 211 - T 12-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 UA74_01335 1078c1db7d3307518219b193f55771d1 312 Gene3D G3DSA:1.10.8.1080 228 306 1.6E-21 T 12-10-2018 UA74_01335 1078c1db7d3307518219b193f55771d1 312 Pfam PF13580 SIS domain 49 167 2.8E-6 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UA74_01335 1078c1db7d3307518219b193f55771d1 312 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 10 304 35.433 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 UA74_01335 1078c1db7d3307518219b193f55771d1 312 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 16 304 1.2E-95 T 12-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 UA74_01335 1078c1db7d3307518219b193f55771d1 312 SUPERFAMILY SSF53697 16 257 3.56E-59 T 12-10-2018 UA74_17280 19c419d2e5cd7fd6c0cd985895ac06ef 349 SUPERFAMILY SSF53335 82 289 4.5E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_17280 19c419d2e5cd7fd6c0cd985895ac06ef 349 Gene3D G3DSA:3.40.50.150 79 275 9.2E-23 T 12-10-2018 UA74_17280 19c419d2e5cd7fd6c0cd985895ac06ef 349 Pfam PF13489 Methyltransferase domain 97 264 7.4E-20 T 12-10-2018 UA74_30030 05363b05783393eb12eba11a2285b915 172 Pfam PF05534 HicB family 109 139 9.2E-6 T 12-10-2018 IPR008651 Uncharacterised protein family HicB UA74_30030 05363b05783393eb12eba11a2285b915 172 Gene3D G3DSA:1.10.1220.10 106 150 1.4E-8 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 UA74_30030 05363b05783393eb12eba11a2285b915 172 SUPERFAMILY SSF47598 105 150 2.22E-12 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 UA74_14265 3704b5a1c53a9c004d7ed3c4d56d4152 321 Pfam PF13602 Zinc-binding dehydrogenase 186 317 7.0E-21 T 12-10-2018 UA74_14265 3704b5a1c53a9c004d7ed3c4d56d4152 321 SMART SM00829 10 317 3.4E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_14265 3704b5a1c53a9c004d7ed3c4d56d4152 321 Gene3D G3DSA:3.90.180.10 11 313 2.1E-81 T 12-10-2018 UA74_14265 3704b5a1c53a9c004d7ed3c4d56d4152 321 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_14265 3704b5a1c53a9c004d7ed3c4d56d4152 321 Gene3D G3DSA:3.40.50.720 127 263 2.1E-81 T 12-10-2018 UA74_14265 3704b5a1c53a9c004d7ed3c4d56d4152 321 SUPERFAMILY SSF51735 119 260 3.7E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14265 3704b5a1c53a9c004d7ed3c4d56d4152 321 SUPERFAMILY SSF50129 1 152 3.62E-25 T 12-10-2018 IPR011032 GroES-like superfamily UA74_18400 d2c90b31796af97b915e11bdf86f0f5e 318 Pfam PF00106 short chain dehydrogenase 15 221 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18400 d2c90b31796af97b915e11bdf86f0f5e 318 Gene3D G3DSA:3.40.50.720 5 309 3.1E-71 T 12-10-2018 UA74_18400 d2c90b31796af97b915e11bdf86f0f5e 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 200 5.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18400 d2c90b31796af97b915e11bdf86f0f5e 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 5.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18400 d2c90b31796af97b915e11bdf86f0f5e 318 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 5.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18400 d2c90b31796af97b915e11bdf86f0f5e 318 SUPERFAMILY SSF51735 7 271 1.07E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_23300 867ee89b37914a6f180c102e1fa0653f 547 SUPERFAMILY SSF52540 313 537 4.83E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_23300 867ee89b37914a6f180c102e1fa0653f 547 Gene3D G3DSA:3.40.50.300 314 541 1.1E-64 T 12-10-2018 UA74_23300 867ee89b37914a6f180c102e1fa0653f 547 SMART SM00382 344 531 2.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_23300 867ee89b37914a6f180c102e1fa0653f 547 Pfam PF00664 ABC transporter transmembrane region 14 236 2.0E-7 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_23300 867ee89b37914a6f180c102e1fa0653f 547 Gene3D G3DSA:1.20.1560.10 2 306 8.9E-19 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_23300 867ee89b37914a6f180c102e1fa0653f 547 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 7 499 1.4E-133 T 12-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 UA74_23300 867ee89b37914a6f180c102e1fa0653f 547 SUPERFAMILY SSF90123 7 454 1.57E-30 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_23300 867ee89b37914a6f180c102e1fa0653f 547 ProSitePatterns PS00211 ABC transporters family signature. 442 456 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_23300 867ee89b37914a6f180c102e1fa0653f 547 Pfam PF00005 ABC transporter 336 469 1.6E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_09685 5bdc05ccbc7322535d8d99cebfe5d912 485 TIGRFAM TIGR01312 XylB: xylulokinase 7 440 3.7E-116 T 12-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 UA74_09685 5bdc05ccbc7322535d8d99cebfe5d912 485 SUPERFAMILY SSF53067 251 441 4.95E-44 T 12-10-2018 UA74_09685 5bdc05ccbc7322535d8d99cebfe5d912 485 Gene3D G3DSA:3.30.420.40 1 240 9.9E-75 T 12-10-2018 UA74_09685 5bdc05ccbc7322535d8d99cebfe5d912 485 SUPERFAMILY SSF53067 6 250 1.69E-64 T 12-10-2018 UA74_09685 5bdc05ccbc7322535d8d99cebfe5d912 485 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 247 7.0E-61 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UA74_09685 5bdc05ccbc7322535d8d99cebfe5d912 485 Gene3D G3DSA:3.30.420.40 250 475 3.1E-56 T 12-10-2018 UA74_09685 5bdc05ccbc7322535d8d99cebfe5d912 485 PIRSF PIRSF000538 3 444 1.4E-132 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_09685 5bdc05ccbc7322535d8d99cebfe5d912 485 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 437 1.1E-26 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UA74_20265 0d4521f9d07d4df6ad74a583e15bb555 212 SUPERFAMILY SSF46689 3 67 3.44E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_20265 0d4521f9d07d4df6ad74a583e15bb555 212 PRINTS PR00400 Tetracycline repressor protein signature 134 153 5.1E-8 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_20265 0d4521f9d07d4df6ad74a583e15bb555 212 PRINTS PR00400 Tetracycline repressor protein signature 187 201 5.1E-8 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_20265 0d4521f9d07d4df6ad74a583e15bb555 212 PRINTS PR00400 Tetracycline repressor protein signature 25 48 5.1E-8 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 UA74_20265 0d4521f9d07d4df6ad74a583e15bb555 212 Gene3D G3DSA:1.10.357.10 2 210 1.5E-55 T 12-10-2018 UA74_20265 0d4521f9d07d4df6ad74a583e15bb555 212 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 204 2.4E-17 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_20265 0d4521f9d07d4df6ad74a583e15bb555 212 SUPERFAMILY SSF48498 76 205 8.67E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_20265 0d4521f9d07d4df6ad74a583e15bb555 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 3.4E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 SUPERFAMILY SSF54909 61 143 4.02E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 Pfam PF01037 Lrp/AsnC ligand binding domain 75 138 1.6E-17 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 5.3E-18 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.6E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.6E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.6E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 SMART SM00344 1 108 7.3E-42 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 Gene3D G3DSA:1.10.10.10 2 52 2.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 Gene3D G3DSA:3.30.70.920 54 135 7.0E-23 T 12-10-2018 UA74_02425 39323b82a4681dfa45e1ff3b05ff7ee3 160 SUPERFAMILY SSF46785 1 60 1.57E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_01895 bf190f5af44ba94d13b0d615486e4767 631 Pfam PF01964 Radical SAM ThiC family 169 589 3.8E-198 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UA74_01895 bf190f5af44ba94d13b0d615486e4767 631 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 169 592 2.3E-207 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UA74_01895 bf190f5af44ba94d13b0d615486e4767 631 Gene3D G3DSA:3.20.20.540 212 525 1.4E-150 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UA74_01895 bf190f5af44ba94d13b0d615486e4767 631 Pfam PF13667 ThiC-associated domain 96 158 2.8E-13 T 12-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UA74_01895 bf190f5af44ba94d13b0d615486e4767 631 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 168 594 95.291 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 SUPERFAMILY SSF81923 3 144 2.75E-32 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 SMART SM01086 719 815 5.1E-32 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 SUPERFAMILY SSF52540 490 801 4.51E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF07724 AAA domain (Cdc48 subfamily) 540 713 6.4E-51 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:1.10.1780.10 1 148 5.4E-64 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 3.9E-17 T 12-10-2018 IPR004176 Clp, N-terminal UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 6.5E-18 T 12-10-2018 IPR004176 Clp, N-terminal UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 719 797 6.0E-24 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:3.40.50.300 471 717 5.0E-96 T 12-10-2018 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 338 4.5E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Pfam PF02151 UvrB/uvrC motif 421 453 5.7E-8 T 12-10-2018 IPR001943 UVR domain GO:0005515 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:1.10.8.60 719 816 7.7E-26 T 12-10-2018 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:3.40.50.300 353 469 1.7E-39 T 12-10-2018 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 Gene3D G3DSA:3.40.50.300 164 352 4.9E-72 T 12-10-2018 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 SUPERFAMILY SSF52540 167 471 5.62E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 SMART SM00382 541 720 5.7E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 SMART SM00382 204 349 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 7.5E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 7.5E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 7.5E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_01625 5670f762cc8f6e514ae4328c575aa51d 851 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 7.5E-39 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 UA74_17970 f601e306ff4c18fb5e4513e2b14377e0 284 Gene3D G3DSA:3.40.50.80 151 283 5.2E-41 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_17970 f601e306ff4c18fb5e4513e2b14377e0 284 SUPERFAMILY SSF63380 14 138 4.38E-11 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_17970 f601e306ff4c18fb5e4513e2b14377e0 284 Pfam PF04954 Siderophore-interacting protein 156 273 1.6E-38 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain UA74_17970 f601e306ff4c18fb5e4513e2b14377e0 284 Pfam PF08021 Siderophore-interacting FAD-binding domain 26 141 2.4E-41 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting UA74_17970 f601e306ff4c18fb5e4513e2b14377e0 284 Gene3D G3DSA:2.40.30.10 5 141 7.7E-43 T 12-10-2018 UA74_20440 7a3d500b8d701f5400c9e8b0c7194e3f 218 Gene3D G3DSA:1.10.10.10 1 69 7.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20440 7a3d500b8d701f5400c9e8b0c7194e3f 218 SMART SM00345 10 68 6.7E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_20440 7a3d500b8d701f5400c9e8b0c7194e3f 218 Pfam PF07729 FCD domain 82 197 3.3E-17 T 12-10-2018 IPR011711 GntR, C-terminal UA74_20440 7a3d500b8d701f5400c9e8b0c7194e3f 218 SMART SM00895 78 201 3.6E-6 T 12-10-2018 IPR011711 GntR, C-terminal UA74_20440 7a3d500b8d701f5400c9e8b0c7194e3f 218 Gene3D G3DSA:1.20.120.530 74 209 5.0E-16 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_20440 7a3d500b8d701f5400c9e8b0c7194e3f 218 SUPERFAMILY SSF48008 84 204 1.67E-15 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_20440 7a3d500b8d701f5400c9e8b0c7194e3f 218 SUPERFAMILY SSF46785 6 72 1.86E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20440 7a3d500b8d701f5400c9e8b0c7194e3f 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 1.5E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_22220 c2bc452c32ee889dff473bfcb42f9b95 267 SMART SM00382 26 210 5.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_22220 c2bc452c32ee889dff473bfcb42f9b95 267 SUPERFAMILY SSF52540 6 218 7.5E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22220 c2bc452c32ee889dff473bfcb42f9b95 267 Pfam PF00005 ABC transporter 18 166 9.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_22220 c2bc452c32ee889dff473bfcb42f9b95 267 Gene3D G3DSA:3.40.50.300 1 249 7.3E-66 T 12-10-2018 UA74_05610 9983a03769b49a4d8900d960f2198d2c 192 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 17 184 4.8E-20 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 UA74_21045 a4640b67202bfa77bc676adb988dd37c 261 Pfam PF13419 Haloacid dehalogenase-like hydrolase 28 198 1.3E-15 T 12-10-2018 UA74_21045 a4640b67202bfa77bc676adb988dd37c 261 Gene3D G3DSA:3.40.50.1000 25 198 2.4E-48 T 12-10-2018 IPR023214 HAD superfamily UA74_21045 a4640b67202bfa77bc676adb988dd37c 261 Gene3D G3DSA:1.10.150.240 39 99 2.4E-48 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_21045 a4640b67202bfa77bc676adb988dd37c 261 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 105 198 4.6E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_21045 a4640b67202bfa77bc676adb988dd37c 261 SUPERFAMILY SSF56784 25 204 6.34E-36 T 12-10-2018 IPR036412 HAD-like superfamily UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 43 60 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 228 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 180 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 245 265 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 129 1.3E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 51 281 8.0E-53 T 12-10-2018 UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 190 209 4.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 129 4.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 178 4.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 Gene3D G3DSA:3.40.50.720 2 283 9.8E-82 T 12-10-2018 UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 177 205 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_07755 f36d201bac3aaeb8d9cd0f38979b3bbe 286 SUPERFAMILY SSF51735 41 283 3.1E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_15525 ca4490eedf3898dff2acf9e212c381a1 331 Pfam PF12833 Helix-turn-helix domain 244 321 2.2E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_15525 ca4490eedf3898dff2acf9e212c381a1 331 SUPERFAMILY SSF46689 275 325 2.51E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_15525 ca4490eedf3898dff2acf9e212c381a1 331 Gene3D G3DSA:1.10.10.60 225 326 4.2E-26 T 12-10-2018 UA74_15525 ca4490eedf3898dff2acf9e212c381a1 331 SUPERFAMILY SSF52317 12 204 3.93E-39 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_15525 ca4490eedf3898dff2acf9e212c381a1 331 SUPERFAMILY SSF46689 227 272 1.36E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_15525 ca4490eedf3898dff2acf9e212c381a1 331 SMART SM00342 238 321 6.1E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_15525 ca4490eedf3898dff2acf9e212c381a1 331 Pfam PF01965 DJ-1/PfpI family 44 181 3.0E-10 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UA74_15525 ca4490eedf3898dff2acf9e212c381a1 331 Gene3D G3DSA:3.40.50.880 9 216 1.5E-48 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_08720 3a1fcbc2359a414a29c9f03fed08df24 687 Gene3D G3DSA:2.120.10.30 11 165 7.0E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_08720 3a1fcbc2359a414a29c9f03fed08df24 687 Gene3D G3DSA:2.120.10.30 217 414 1.1E-9 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_08720 3a1fcbc2359a414a29c9f03fed08df24 687 SUPERFAMILY SSF82171 29 397 6.15E-26 T 12-10-2018 UA74_08720 3a1fcbc2359a414a29c9f03fed08df24 687 Pfam PF00326 Prolyl oligopeptidase family 472 674 2.1E-45 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_08720 3a1fcbc2359a414a29c9f03fed08df24 687 SUPERFAMILY SSF53474 427 674 1.09E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08720 3a1fcbc2359a414a29c9f03fed08df24 687 Gene3D G3DSA:3.40.50.1820 421 678 3.2E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08720 3a1fcbc2359a414a29c9f03fed08df24 687 Pfam PF07676 WD40-like Beta Propeller Repeat 72 108 4.9E-5 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 SUPERFAMILY SSF52418 99 348 1.11E-80 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 PIRSF PIRSF000478 29 455 2.9E-149 T 12-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 SUPERFAMILY SSF47648 31 98 4.32E-20 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 SUPERFAMILY SSF54680 353 456 7.72E-21 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 Gene3D G3DSA:1.20.970.10 30 96 3.2E-23 T 12-10-2018 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 139 154 - T 12-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 Pfam PF02885 Glycosyl transferase family, helical bundle domain 33 95 3.8E-17 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 Pfam PF00591 Glycosyl transferase family, a/b domain 106 331 4.1E-32 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 33 435 4.1E-162 T 12-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 SMART SM00941 366 440 6.9E-23 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 Gene3D G3DSA:3.40.1030.10 106 351 6.0E-132 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 367 439 5.8E-17 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_27465 60c94285093683a9c0b5d8b8751bd281 461 Gene3D G3DSA:3.90.1170.30 352 439 6.0E-132 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_10645 8c6ebe89df64a5d8fbf46e03b95bc45a 711 Pfam PF01061 ABC-2 type transporter 519 665 2.7E-10 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_10645 8c6ebe89df64a5d8fbf46e03b95bc45a 711 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 492 698 5.1E-52 T 12-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal UA74_10645 8c6ebe89df64a5d8fbf46e03b95bc45a 711 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 1.6E-42 T 12-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal UA74_10500 30092820cf662b4db058fdf50a6de82f 383 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 331 342 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site UA74_10500 30092820cf662b4db058fdf50a6de82f 383 PIRSF PIRSF001134 2 383 7.2E-124 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 303 320 4.2E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 346 360 4.2E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 221 235 4.2E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 322 345 4.2E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 282 302 4.2E-43 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 Gene3D G3DSA:3.30.300.50 35 115 1.0E-8 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_10500 30092820cf662b4db058fdf50a6de82f 383 Pfam PF02983 Alpha-lytic protease prodomain 119 179 4.1E-12 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 Pfam PF00089 Trypsin 222 373 3.9E-9 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 Gene3D G3DSA:2.40.10.10 269 368 3.3E-71 T 12-10-2018 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 Gene3D G3DSA:2.40.10.10 200 379 3.3E-71 T 12-10-2018 UA74_10500 30092820cf662b4db058fdf50a6de82f 383 SUPERFAMILY SSF50494 204 375 2.29E-36 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_10500 30092820cf662b4db058fdf50a6de82f 383 Gene3D G3DSA:3.30.300.50 118 188 6.0E-9 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_11540 2f1b8fb3d15f5c3477252fd2e44d2e2a 381 TIGRFAM TIGR00109 hemH: ferrochelatase 29 335 8.4E-43 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UA74_11540 2f1b8fb3d15f5c3477252fd2e44d2e2a 381 Hamap MF_00323 Ferrochelatase [hemH]. 26 337 31.629 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UA74_11540 2f1b8fb3d15f5c3477252fd2e44d2e2a 381 SUPERFAMILY SSF53800 27 347 3.27E-84 T 12-10-2018 UA74_11540 2f1b8fb3d15f5c3477252fd2e44d2e2a 381 Gene3D G3DSA:3.40.50.1400 30 333 1.0E-117 T 12-10-2018 UA74_11540 2f1b8fb3d15f5c3477252fd2e44d2e2a 381 Gene3D G3DSA:3.40.50.1400 170 318 1.0E-117 T 12-10-2018 UA74_11540 2f1b8fb3d15f5c3477252fd2e44d2e2a 381 Pfam PF00762 Ferrochelatase 28 335 9.4E-96 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UA74_17835 40d23c8206d8ed6014637ef947ca21c7 336 SUPERFAMILY SSF75005 49 327 2.57E-63 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_17835 40d23c8206d8ed6014637ef947ca21c7 336 Gene3D G3DSA:2.115.10.20 50 335 2.8E-85 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_17835 40d23c8206d8ed6014637ef947ca21c7 336 Pfam PF04616 Glycosyl hydrolases family 43 51 325 2.3E-44 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 193 215 2.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 320 335 2.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 274 285 2.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 350 361 2.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 156 171 2.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 292 319 2.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 139 155 2.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 341 350 2.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00359 B-class P450 signature 92 103 2.5E-55 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00385 P450 superfamily signature 341 350 1.2E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00385 P450 superfamily signature 239 256 1.2E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00385 P450 superfamily signature 350 361 1.2E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 PRINTS PR00385 P450 superfamily signature 274 285 1.2E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 Gene3D G3DSA:1.10.630.10 2 401 9.8E-122 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 Pfam PF00067 Cytochrome P450 45 370 4.1E-24 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06850 59a0d228e8b18504662add952e34fc1d 401 SUPERFAMILY SSF48264 10 401 5.24E-93 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_29395 e8d2f900437ef52dc18d3318929460d0 276 Pfam PF13560 Helix-turn-helix domain 12 73 1.4E-11 T 12-10-2018 UA74_29395 e8d2f900437ef52dc18d3318929460d0 276 Gene3D G3DSA:1.10.260.40 4 70 4.1E-8 T 12-10-2018 UA74_29395 e8d2f900437ef52dc18d3318929460d0 276 SUPERFAMILY SSF47413 11 70 4.83E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_29395 e8d2f900437ef52dc18d3318929460d0 276 SMART SM00530 16 71 2.7E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 20 428 8.5E-183 T 12-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 ProSitePatterns PS00480 Citrate synthase signature. 309 321 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 Gene3D G3DSA:1.10.230.10 273 382 5.0E-141 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain UA74_28230 1cd84e31e6910e062529d26bf525903f 434 SUPERFAMILY SSF48256 12 434 7.85E-159 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 PIRSF PIRSF001369 42 434 4.2E-156 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type UA74_28230 1cd84e31e6910e062529d26bf525903f 434 Gene3D G3DSA:2.20.28.60 5 55 8.4E-15 T 12-10-2018 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 Pfam PF00285 Citrate synthase, C-terminal domain 51 417 8.6E-134 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 246 274 1.5E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 302 322 1.5E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 385 399 1.5E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 365 381 1.5E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 170 183 1.5E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 PRINTS PR00143 Citrate synthase signature 224 239 1.5E-53 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_28230 1cd84e31e6910e062529d26bf525903f 434 Gene3D G3DSA:1.10.580.10 62 417 5.0E-141 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 430 2.5E-128 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 Pfam PF00344 SecY translocase 75 418 2.7E-114 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 ProSitePatterns PS00755 Protein secY signature 1. 75 94 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 ProSitePatterns PS00756 Protein secY signature 2. 176 193 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 434 29.183 T 12-10-2018 IPR026593 Protein translocase subunit SecY UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 183 206 2.8E-99 T 12-10-2018 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 2.8E-99 T 12-10-2018 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 312 334 2.8E-99 T 12-10-2018 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 367 385 2.8E-99 T 12-10-2018 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.8E-99 T 12-10-2018 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 2.8E-99 T 12-10-2018 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 403 421 2.8E-99 T 12-10-2018 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 157 182 2.8E-99 T 12-10-2018 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 2.8E-99 T 12-10-2018 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 SUPERFAMILY SSF103491 2 425 1.31E-122 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 Gene3D G3DSA:1.10.3370.10 1 430 6.1E-160 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_03095 4fc4d19fe499f2ddd89310587cc580a3 435 PIRSF PIRSF004557 1 435 6.2E-123 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_08050 c44ae09f5218cc5550cd55b23347dcef 110 Gene3D G3DSA:1.10.443.10 1 68 2.3E-9 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_08050 c44ae09f5218cc5550cd55b23347dcef 110 SUPERFAMILY SSF56349 3 63 3.83E-9 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_05625 929dadf32e27154ead36a8ee0a9262de 196 Pfam PF03737 Aldolase/RraA 16 161 3.1E-41 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein UA74_05625 929dadf32e27154ead36a8ee0a9262de 196 Gene3D G3DSA:3.50.30.100 7 184 4.6E-49 T 12-10-2018 UA74_05625 929dadf32e27154ead36a8ee0a9262de 196 SUPERFAMILY SSF89562 12 172 7.46E-42 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily UA74_20450 4be9b1877ac8631a5e559e70f6250002 1227 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 271 281 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UA74_20450 4be9b1877ac8631a5e559e70f6250002 1227 PRINTS PR00723 Subtilisin serine protease family (S8) signature 230 249 2.5E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_20450 4be9b1877ac8631a5e559e70f6250002 1227 PRINTS PR00723 Subtilisin serine protease family (S8) signature 267 280 2.5E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_20450 4be9b1877ac8631a5e559e70f6250002 1227 PRINTS PR00723 Subtilisin serine protease family (S8) signature 437 453 2.5E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_20450 4be9b1877ac8631a5e559e70f6250002 1227 Gene3D G3DSA:3.40.50.200 206 498 3.8E-90 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_20450 4be9b1877ac8631a5e559e70f6250002 1227 Pfam PF00082 Subtilase family 230 487 4.0E-54 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_20450 4be9b1877ac8631a5e559e70f6250002 1227 SUPERFAMILY SSF52743 211 495 3.01E-80 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_20450 4be9b1877ac8631a5e559e70f6250002 1227 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 438 448 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_11490 6da6f597da997bb610ebe645fb6632d5 454 Gene3D G3DSA:3.90.1720.10 243 454 2.9E-56 T 12-10-2018 UA74_11490 6da6f597da997bb610ebe645fb6632d5 454 Pfam PF00877 NlpC/P60 family 330 451 1.0E-27 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UA74_11490 6da6f597da997bb610ebe645fb6632d5 454 SUPERFAMILY SSF54001 314 443 3.04E-34 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.82 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 SUPERFAMILY SSF56053 1 83 1.31E-25 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 PIRSF PIRSF002162 1 178 1.1E-45 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 Gene3D G3DSA:3.90.930.12 84 179 1.6E-39 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 SUPERFAMILY SSF56053 84 178 1.23E-35 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 Gene3D G3DSA:3.90.930.12 1 83 1.9E-29 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 4.9E-33 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 4.9E-33 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 4.9E-33 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.9E-73 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 Pfam PF00347 Ribosomal protein L6 11 83 4.9E-18 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03020 e5b607df38fc7d2b505c413d8809569a 179 Pfam PF00347 Ribosomal protein L6 92 165 6.6E-20 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02965 d901552bec15744b79ad68d27e93f833 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.002 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02965 d901552bec15744b79ad68d27e93f833 93 PIRSF PIRSF002144 1 93 3.0E-30 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02965 d901552bec15744b79ad68d27e93f833 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 6.2E-47 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_02965 d901552bec15744b79ad68d27e93f833 93 Gene3D G3DSA:3.30.860.10 1 93 8.4E-39 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02965 d901552bec15744b79ad68d27e93f833 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02965 d901552bec15744b79ad68d27e93f833 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.0E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02965 d901552bec15744b79ad68d27e93f833 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.0E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02965 d901552bec15744b79ad68d27e93f833 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.0E-23 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02965 d901552bec15744b79ad68d27e93f833 93 Pfam PF00203 Ribosomal protein S19 3 83 6.4E-36 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02965 d901552bec15744b79ad68d27e93f833 93 SUPERFAMILY SSF54570 3 84 4.58E-35 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02700 228047d40c030e323c30c45e5235ad9f 235 Gene3D G3DSA:3.60.15.10 1 233 2.0E-44 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_02700 228047d40c030e323c30c45e5235ad9f 235 SMART SM00849 17 212 1.5E-26 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_02700 228047d40c030e323c30c45e5235ad9f 235 Pfam PF00753 Metallo-beta-lactamase superfamily 15 212 8.7E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_02700 228047d40c030e323c30c45e5235ad9f 235 SUPERFAMILY SSF56281 4 226 1.76E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_01220 c4526bcd498de3818c88ba204600ffa1 304 Gene3D G3DSA:3.30.360.10 145 304 4.9E-13 T 12-10-2018 UA74_01220 c4526bcd498de3818c88ba204600ffa1 304 Gene3D G3DSA:3.40.50.720 3 144 1.9E-32 T 12-10-2018 UA74_01220 c4526bcd498de3818c88ba204600ffa1 304 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 12 123 2.6E-18 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_01220 c4526bcd498de3818c88ba204600ffa1 304 SUPERFAMILY SSF51735 8 142 4.24E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_01220 c4526bcd498de3818c88ba204600ffa1 304 SUPERFAMILY SSF55347 167 255 5.67E-8 T 12-10-2018 UA74_01870 41a1b3e17bce8968c799e377046846a2 381 Gene3D G3DSA:3.30.420.40 8 121 6.1E-59 T 12-10-2018 UA74_01870 41a1b3e17bce8968c799e377046846a2 381 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 9 316 1.2E-20 T 12-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 UA74_01870 41a1b3e17bce8968c799e377046846a2 381 Gene3D G3DSA:3.30.420.40 122 275 6.1E-59 T 12-10-2018 UA74_01870 41a1b3e17bce8968c799e377046846a2 381 SUPERFAMILY SSF53067 7 118 2.59E-14 T 12-10-2018 UA74_01870 41a1b3e17bce8968c799e377046846a2 381 SUPERFAMILY SSF53067 122 317 1.64E-32 T 12-10-2018 UA74_17900 837ac56b9e2acbe63c6596e5dbc91f60 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 134 4.7E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_17900 837ac56b9e2acbe63c6596e5dbc91f60 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 149 169 4.7E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_17900 837ac56b9e2acbe63c6596e5dbc91f60 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 114 4.7E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_17900 837ac56b9e2acbe63c6596e5dbc91f60 181 Gene3D G3DSA:1.10.10.10 34 175 2.4E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17900 837ac56b9e2acbe63c6596e5dbc91f60 181 SUPERFAMILY SSF46785 28 170 1.78E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_17900 837ac56b9e2acbe63c6596e5dbc91f60 181 Pfam PF01047 MarR family 67 123 4.5E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_17900 837ac56b9e2acbe63c6596e5dbc91f60 181 SMART SM00347 59 159 6.8E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_08630 ce1c7fd494a3377ef6cf8be3500603ad 348 SUPERFAMILY SSF101898 19 258 4.45E-8 T 12-10-2018 UA74_04935 436030ef311a38d2ae5cd69609433c94 158 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site UA74_04935 436030ef311a38d2ae5cd69609433c94 158 SUPERFAMILY SSF74982 4 133 1.7E-51 T 12-10-2018 IPR023620 Small protein B UA74_04935 436030ef311a38d2ae5cd69609433c94 158 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 71.383 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 UA74_04935 436030ef311a38d2ae5cd69609433c94 158 Pfam PF01668 SmpB protein 10 150 1.6E-59 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 UA74_04935 436030ef311a38d2ae5cd69609433c94 158 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 131 1.0E-47 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 UA74_04935 436030ef311a38d2ae5cd69609433c94 158 Gene3D G3DSA:2.40.280.10 2 130 6.5E-48 T 12-10-2018 IPR023620 Small protein B UA74_04935 436030ef311a38d2ae5cd69609433c94 158 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 7.6E-57 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 UA74_23625 cedf5dbd2dea93d8361af025e79a0174 430 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 36 428 1.5E-138 T 12-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_23625 cedf5dbd2dea93d8361af025e79a0174 430 Gene3D G3DSA:3.90.1150.10 42 419 6.1E-135 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_23625 cedf5dbd2dea93d8361af025e79a0174 430 SUPERFAMILY SSF53383 35 429 1.05E-118 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_23625 cedf5dbd2dea93d8361af025e79a0174 430 Gene3D G3DSA:3.40.640.10 88 338 6.1E-135 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_23625 cedf5dbd2dea93d8361af025e79a0174 430 Pfam PF00202 Aminotransferase class-III 47 427 2.7E-113 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_23625 cedf5dbd2dea93d8361af025e79a0174 430 PIRSF PIRSF000521 2 196 4.1E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_23625 cedf5dbd2dea93d8361af025e79a0174 430 PIRSF PIRSF000521 202 430 1.2E-26 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_23625 cedf5dbd2dea93d8361af025e79a0174 430 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 253 290 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_06235 d9567f9950263d2e572e59e98ef4a79f 191 Pfam PF01694 Rhomboid family 45 176 6.6E-21 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 UA74_06235 d9567f9950263d2e572e59e98ef4a79f 191 SUPERFAMILY SSF144091 3 177 3.27E-24 T 12-10-2018 UA74_06235 d9567f9950263d2e572e59e98ef4a79f 191 Gene3D G3DSA:1.20.1540.10 43 183 3.8E-13 T 12-10-2018 IPR035952 Rhomboid-like superfamily UA74_08160 6113e589605fade79c80ad0bef74162d 655 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 13 620 3.9E-206 T 12-10-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM UA74_08160 6113e589605fade79c80ad0bef74162d 655 SMART SM00729 264 487 2.0E-30 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_08160 6113e589605fade79c80ad0bef74162d 655 Pfam PF04055 Radical SAM superfamily 268 432 4.5E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_08160 6113e589605fade79c80ad0bef74162d 655 SUPERFAMILY SSF102114 226 634 5.36E-50 T 12-10-2018 UA74_08160 6113e589605fade79c80ad0bef74162d 655 Gene3D G3DSA:3.80.30.20 263 494 5.9E-19 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UA74_13435 a0e7a7c2a7894f6f238605d2b0823f7b 445 SUPERFAMILY SSF46785 4 82 6.53E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_13435 a0e7a7c2a7894f6f238605d2b0823f7b 445 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.7E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_13435 a0e7a7c2a7894f6f238605d2b0823f7b 445 Gene3D G3DSA:3.90.1150.10 115 432 5.5E-60 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_13435 a0e7a7c2a7894f6f238605d2b0823f7b 445 Pfam PF00155 Aminotransferase class I and II 125 430 2.8E-16 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_13435 a0e7a7c2a7894f6f238605d2b0823f7b 445 SUPERFAMILY SSF53383 115 435 2.99E-63 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_13435 a0e7a7c2a7894f6f238605d2b0823f7b 445 Gene3D G3DSA:3.40.640.10 119 333 5.5E-60 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_13435 a0e7a7c2a7894f6f238605d2b0823f7b 445 SMART SM00345 7 66 1.2E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_13435 a0e7a7c2a7894f6f238605d2b0823f7b 445 Gene3D G3DSA:1.10.10.10 3 74 6.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17715 10d75033133ea4eb724f659855b01113 532 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 3 521 1.1E-40 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 UA74_17715 10d75033133ea4eb724f659855b01113 532 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 25 480 1.5E-68 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 UA74_30320 e8fecbb344050c4995a72707c489b08a 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 4.1E-19 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30320 e8fecbb344050c4995a72707c489b08a 45 Pfam PF00468 Ribosomal protein L34 3 45 1.2E-19 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30320 e8fecbb344050c4995a72707c489b08a 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 12-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_30320 e8fecbb344050c4995a72707c489b08a 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.739 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30320 e8fecbb344050c4995a72707c489b08a 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 23 3.0E-5 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_16320 d799d319e0092ab7d24f36e626a0ab76 370 Pfam PF09661 Protein of unknown function (DUF2398) 18 360 2.2E-73 T 12-10-2018 IPR013494 Conserved hypothetical protein CHP02678 UA74_18990 818ab277a27f313b6cef0a8ed04c9889 377 SUPERFAMILY SSF81345 35 370 3.66E-73 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_18990 818ab277a27f313b6cef0a8ed04c9889 377 Pfam PF01032 FecCD transport family 49 369 3.1E-88 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_18990 818ab277a27f313b6cef0a8ed04c9889 377 Gene3D G3DSA:1.10.3470.10 35 373 2.9E-93 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_02895 ea9466da2773d9c4afb5edbf3bd7ba58 392 Gene3D G3DSA:3.30.565.10 262 385 4.7E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_02895 ea9466da2773d9c4afb5edbf3bd7ba58 392 SUPERFAMILY SSF55874 265 376 5.47E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_02895 ea9466da2773d9c4afb5edbf3bd7ba58 392 Pfam PF07730 Histidine kinase 197 262 2.6E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_18550 26a508ff3ef7eeccd472f59f2fded25c 120 Pfam PF03795 YCII-related domain 2 112 1.1E-11 T 12-10-2018 IPR005545 YCII-related UA74_18550 26a508ff3ef7eeccd472f59f2fded25c 120 SUPERFAMILY SSF54909 2 114 5.36E-29 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_18550 26a508ff3ef7eeccd472f59f2fded25c 120 Gene3D G3DSA:3.30.70.1060 1 117 5.8E-37 T 12-10-2018 UA74_06220 d56de3b0464cc99325938d996c4dc481 92 SUPERFAMILY SSF54285 1 90 1.6E-23 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp UA74_06220 d56de3b0464cc99325938d996c4dc481 92 Gene3D G3DSA:3.10.20.30 1 90 2.2E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily UA74_06220 d56de3b0464cc99325938d996c4dc481 92 Pfam PF02597 ThiS family 5 90 4.0E-19 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 UA74_20610 66606712e6e43938a176e8c6373b6483 714 SUPERFAMILY SSF48452 505 691 3.13E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_20610 66606712e6e43938a176e8c6373b6483 714 PRINTS PR00364 Disease resistance protein signature 160 174 1.0E-9 T 12-10-2018 UA74_20610 66606712e6e43938a176e8c6373b6483 714 PRINTS PR00364 Disease resistance protein signature 248 262 1.0E-9 T 12-10-2018 UA74_20610 66606712e6e43938a176e8c6373b6483 714 PRINTS PR00364 Disease resistance protein signature 82 97 1.0E-9 T 12-10-2018 UA74_20610 66606712e6e43938a176e8c6373b6483 714 Gene3D G3DSA:3.40.50.300 43 208 6.8E-25 T 12-10-2018 UA74_20610 66606712e6e43938a176e8c6373b6483 714 Pfam PF00931 NB-ARC domain 69 280 8.6E-7 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_20610 66606712e6e43938a176e8c6373b6483 714 SUPERFAMILY SSF52540 47 309 1.37E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20610 66606712e6e43938a176e8c6373b6483 714 Gene3D G3DSA:1.25.40.10 474 712 5.4E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_09345 831dc41d2250de40d919fb3c779c2951 317 Gene3D G3DSA:2.40.30.30 186 317 4.8E-45 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 UA74_09345 831dc41d2250de40d919fb3c779c2951 317 SMART SM00904 183 314 1.5E-53 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 UA74_09345 831dc41d2250de40d919fb3c779c2951 317 SUPERFAMILY SSF52374 16 175 1.16E-31 T 12-10-2018 UA74_09345 831dc41d2250de40d919fb3c779c2951 317 PIRSF PIRSF004491 1 317 3.4E-99 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 UA74_09345 831dc41d2250de40d919fb3c779c2951 317 Pfam PF06574 FAD synthetase 12 166 1.7E-50 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 UA74_09345 831dc41d2250de40d919fb3c779c2951 317 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 313 2.0E-71 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 UA74_09345 831dc41d2250de40d919fb3c779c2951 317 Pfam PF01687 Riboflavin kinase 184 313 1.1E-35 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 UA74_09345 831dc41d2250de40d919fb3c779c2951 317 SUPERFAMILY SSF82114 174 314 1.09E-40 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 UA74_09345 831dc41d2250de40d919fb3c779c2951 317 Gene3D G3DSA:3.40.50.620 1 185 1.5E-61 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 Pfam PF01168 Alanine racemase, N-terminal domain 27 241 5.8E-51 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 Pfam PF00842 Alanine racemase, C-terminal domain 252 375 2.4E-35 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 SUPERFAMILY SSF50621 247 375 8.37E-38 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 TIGRFAM TIGR00492 alr: alanine racemase 27 374 2.8E-68 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 Hamap MF_01201 Alanine racemase. 16 377 25.99 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 SMART SM01005 250 377 1.2E-49 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 Gene3D G3DSA:3.20.20.10 27 236 9.7E-102 T 12-10-2018 IPR029066 PLP-binding barrel UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 283 298 1.2E-48 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 304 321 1.2E-48 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 76 94 1.2E-48 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 214 241 1.2E-48 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 359 372 1.2E-48 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 266 281 1.2E-48 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 40 56 1.2E-48 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 171 182 1.2E-48 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 PRINTS PR00992 Alanine racemase signature 134 146 1.2E-48 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 SUPERFAMILY SSF51419 27 245 9.35E-45 T 12-10-2018 IPR029066 PLP-binding barrel UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 45 55 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_19210 491e3b8a6314306d4829617d7cb046a5 377 Gene3D G3DSA:2.40.37.10 250 374 9.7E-102 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UA74_03845 1f4edb12a701aa4415cdc83a172469d8 368 SUPERFAMILY SSF52266 135 328 3.0E-25 T 12-10-2018 UA74_03845 1f4edb12a701aa4415cdc83a172469d8 368 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 139 315 1.7E-15 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain UA74_03845 1f4edb12a701aa4415cdc83a172469d8 368 Gene3D G3DSA:3.40.50.1110 117 326 2.5E-17 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_21130 ad04e7847dcd3c2dd3057abcc6b27526 269 SUPERFAMILY SSF53335 16 256 1.1E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_21130 ad04e7847dcd3c2dd3057abcc6b27526 269 Pfam PF01209 ubiE/COQ5 methyltransferase family 32 144 8.4E-19 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UA74_21130 ad04e7847dcd3c2dd3057abcc6b27526 269 Gene3D G3DSA:3.40.50.150 6 256 5.6E-35 T 12-10-2018 UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 SUPERFAMILY SSF52540 538 1106 7.78E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 Gene3D G3DSA:3.40.50.300 938 1122 5.6E-38 T 12-10-2018 UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 Pfam PF13087 AAA domain 919 1099 2.3E-29 T 12-10-2018 UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 Pfam PF13086 AAA domain 540 887 1.9E-19 T 12-10-2018 UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 Pfam PF00656 Caspase domain 7 203 8.1E-11 T 12-10-2018 UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 Gene3D G3DSA:3.40.50.1460 4 248 2.5E-20 T 12-10-2018 UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 Gene3D G3DSA:3.40.50.300 490 712 3.0E-23 T 12-10-2018 UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 Gene3D G3DSA:3.40.50.300 721 912 1.6E-13 T 12-10-2018 UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 SUPERFAMILY SSF52129 3 201 2.37E-14 T 12-10-2018 IPR029030 Caspase-like domain superfamily UA74_21390 72ea632dca0a1782e148c36c526d0c67 1220 ProSitePatterns PS00018 EF-hand calcium-binding domain. 205 217 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site UA74_20290 8b4b0a1c03e34f75f6704bd407e651ec 117 Gene3D G3DSA:1.10.10.10 31 86 1.7E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20290 8b4b0a1c03e34f75f6704bd407e651ec 117 Pfam PF05331 Protein of unknown function (DUF742) 6 115 7.0E-36 T 12-10-2018 IPR007995 Protein of unknown function DUF742 UA74_12535 a7ad1e832cc325f410fe81df61f017ff 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 1.6E-103 T 12-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 UA74_12535 a7ad1e832cc325f410fe81df61f017ff 256 Pfam PF00005 ABC transporter 23 174 2.9E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_12535 a7ad1e832cc325f410fe81df61f017ff 256 SUPERFAMILY SSF52540 4 234 4.18E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12535 a7ad1e832cc325f410fe81df61f017ff 256 Gene3D G3DSA:3.40.50.300 1 244 1.8E-52 T 12-10-2018 UA74_12535 a7ad1e832cc325f410fe81df61f017ff 256 SMART SM00382 32 225 3.9E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_12370 c0f7a99434f3c8ff3ba0205df46c93cc 113 Pfam PF13397 RNA polymerase-binding protein 5 108 5.8E-42 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 UA74_12370 c0f7a99434f3c8ff3ba0205df46c93cc 113 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 113 25.233 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 UA74_12370 c0f7a99434f3c8ff3ba0205df46c93cc 113 Gene3D G3DSA:2.20.28.270 1 81 2.3E-13 T 12-10-2018 IPR038638 RbpA superfamily UA74_21455 b5cb65ca94d8a056eb91ca9cefc342c1 347 Gene3D G3DSA:1.10.10.10 160 249 6.2E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21455 b5cb65ca94d8a056eb91ca9cefc342c1 347 SUPERFAMILY SSF46785 251 324 9.52E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_21455 b5cb65ca94d8a056eb91ca9cefc342c1 347 Pfam PF04079 Segregation and condensation complex subunit ScpB 175 333 4.3E-48 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 UA74_21455 b5cb65ca94d8a056eb91ca9cefc342c1 347 SUPERFAMILY SSF46785 172 246 1.12E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_21455 b5cb65ca94d8a056eb91ca9cefc342c1 347 Gene3D G3DSA:1.10.10.10 250 343 4.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21455 b5cb65ca94d8a056eb91ca9cefc342c1 347 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 173 334 1.9E-29 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 UA74_09105 7a42deb536d4eeb120b5cd521bae0a81 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 145 2.0E-15 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase UA74_09105 7a42deb536d4eeb120b5cd521bae0a81 146 PIRSF PIRSF017371 1 146 2.2E-52 T 12-10-2018 IPR014488 Uncharacterised conserved protein UCP017371 UA74_09105 7a42deb536d4eeb120b5cd521bae0a81 146 SUPERFAMILY SSF55961 5 144 2.17E-9 T 12-10-2018 UA74_03030 3791e9b816d962446f217ff1d73d4264 201 Pfam PF03719 Ribosomal protein S5, C-terminal domain 110 180 3.3E-28 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 UA74_03030 3791e9b816d962446f217ff1d73d4264 201 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 35 186 3.3E-67 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_03030 3791e9b816d962446f217ff1d73d4264 201 Gene3D G3DSA:3.30.230.10 100 189 3.5E-34 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_03030 3791e9b816d962446f217ff1d73d4264 201 Gene3D G3DSA:3.30.160.20 27 95 1.6E-28 T 12-10-2018 UA74_03030 3791e9b816d962446f217ff1d73d4264 201 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 4 186 33.888 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_03030 3791e9b816d962446f217ff1d73d4264 201 ProSitePatterns PS00585 Ribosomal protein S5 signature. 51 83 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site UA74_03030 3791e9b816d962446f217ff1d73d4264 201 Pfam PF00333 Ribosomal protein S5, N-terminal domain 36 98 1.0E-27 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 UA74_03030 3791e9b816d962446f217ff1d73d4264 201 SUPERFAMILY SSF54211 102 181 5.56E-24 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_03030 3791e9b816d962446f217ff1d73d4264 201 SUPERFAMILY SSF54768 34 99 2.83E-22 T 12-10-2018 UA74_10200 0e8293e96e9d75ef5c53bd355fd76a93 264 Pfam PF01925 Sulfite exporter TauE/SafE 18 257 3.0E-27 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_26865 f9ed89cb2cbb36a0922fe9fed5201fd2 547 Gene3D G3DSA:3.90.226.10 10 276 4.2E-92 T 12-10-2018 UA74_26865 f9ed89cb2cbb36a0922fe9fed5201fd2 547 SUPERFAMILY SSF52096 262 547 8.13E-88 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_26865 f9ed89cb2cbb36a0922fe9fed5201fd2 547 SUPERFAMILY SSF52096 24 274 1.99E-74 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_26865 f9ed89cb2cbb36a0922fe9fed5201fd2 547 Gene3D G3DSA:3.90.226.10 282 547 1.9E-92 T 12-10-2018 UA74_26865 f9ed89cb2cbb36a0922fe9fed5201fd2 547 Pfam PF01039 Carboxyl transferase domain 46 545 6.3E-191 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 UA74_04215 8ce99cfed19f5aafa6bddeb82bf5cd19 287 SUPERFAMILY SSF53335 16 256 3.55E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_04215 8ce99cfed19f5aafa6bddeb82bf5cd19 287 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 40 67 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 UA74_04215 8ce99cfed19f5aafa6bddeb82bf5cd19 287 Pfam PF00398 Ribosomal RNA adenine dimethylase 10 253 1.0E-31 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm UA74_04215 8ce99cfed19f5aafa6bddeb82bf5cd19 287 SMART SM00650 24 185 1.8E-61 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 UA74_04215 8ce99cfed19f5aafa6bddeb82bf5cd19 287 Gene3D G3DSA:3.40.50.150 4 186 1.9E-39 T 12-10-2018 UA74_01395 e7f1e76eca346265bda274e4dfdeaae7 425 Pfam PF00437 Type II/IV secretion system protein 93 372 2.1E-68 T 12-10-2018 IPR001482 Type II/IV secretion system protein UA74_01395 e7f1e76eca346265bda274e4dfdeaae7 425 Gene3D G3DSA:3.40.50.300 193 393 3.6E-52 T 12-10-2018 UA74_01395 e7f1e76eca346265bda274e4dfdeaae7 425 SUPERFAMILY SSF52540 75 378 3.6E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01395 e7f1e76eca346265bda274e4dfdeaae7 425 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 41 384 1.0E-149 T 12-10-2018 IPR022399 Helicase/secretion neighbourhood ATPase UA74_01395 e7f1e76eca346265bda274e4dfdeaae7 425 Gene3D G3DSA:3.30.450.90 90 192 1.1E-21 T 12-10-2018 UA74_21880 3db43d9dc73199bca0befd214c219975 321 PIRSF PIRSF016838 1 52 5.5E-4 T 12-10-2018 IPR028349 Protein PafC UA74_21880 3db43d9dc73199bca0befd214c219975 321 PIRSF PIRSF016838 67 321 4.9E-16 T 12-10-2018 IPR028349 Protein PafC UA74_21880 3db43d9dc73199bca0befd214c219975 321 SUPERFAMILY SSF46785 5 63 6.33E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_21880 3db43d9dc73199bca0befd214c219975 321 Pfam PF13280 WYL domain 140 316 1.0E-40 T 12-10-2018 IPR026881 WYL domain UA74_21880 3db43d9dc73199bca0befd214c219975 321 Gene3D G3DSA:1.10.10.10 1 64 7.9E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21880 3db43d9dc73199bca0befd214c219975 321 Pfam PF08279 HTH domain 8 60 5.0E-15 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 UA74_10065 6bd8071d910488f3afee540ced57fa62 241 TIGRFAM TIGR00017 cmk: cytidylate kinase 9 220 8.3E-59 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 UA74_10065 6bd8071d910488f3afee540ced57fa62 241 SUPERFAMILY SSF52540 9 227 9.66E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10065 6bd8071d910488f3afee540ced57fa62 241 Pfam PF02224 Cytidylate kinase 10 226 3.2E-63 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 UA74_10065 6bd8071d910488f3afee540ced57fa62 241 Gene3D G3DSA:3.40.50.300 5 231 4.4E-72 T 12-10-2018 UA74_10065 6bd8071d910488f3afee540ced57fa62 241 Hamap MF_00238 Cytidylate kinase [cmk]. 8 231 29.339 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF48452 727 874 2.09E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF48452 851 966 1.14E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:3.40.50.300 275 430 3.0E-22 T 12-10-2018 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF48452 93 256 1.24E-29 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF46894 2 81 2.21E-5 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:1.25.40.10 852 996 2.7E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:1.25.40.10 712 851 3.6E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:1.10.10.10 1 92 2.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM01043 97 242 2.0E-32 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 Pfam PF03704 Bacterial transcriptional activator domain 97 240 7.8E-26 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 Gene3D G3DSA:1.25.40.10 95 253 7.8E-33 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SUPERFAMILY SSF52540 280 546 8.26E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 732 765 270.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 772 805 420.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 192 225 190.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 895 928 0.68 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 855 891 460.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 935 968 170.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 SMART SM00028 812 845 260.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 Pfam PF00931 NB-ARC domain 307 550 4.9E-11 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 Pfam PF13424 Tetratricopeptide repeat 856 924 6.3E-9 T 12-10-2018 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 PRINTS PR00364 Disease resistance protein signature 389 403 1.5E-9 T 12-10-2018 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 PRINTS PR00364 Disease resistance protein signature 311 326 1.5E-9 T 12-10-2018 UA74_06380 fdf2fb93aa15655f814b6a47e7f1f101 1001 PRINTS PR00364 Disease resistance protein signature 476 490 1.5E-9 T 12-10-2018 UA74_25000 e0a8ab374cb91c29353f5c877960fa82 123 SUPERFAMILY SSF89360 15 110 3.73E-26 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UA74_25000 e0a8ab374cb91c29353f5c877960fa82 123 Gene3D G3DSA:2.60.300.12 18 123 2.9E-27 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UA74_25000 e0a8ab374cb91c29353f5c877960fa82 123 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 120 2.3E-18 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 UA74_25000 e0a8ab374cb91c29353f5c877960fa82 123 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 105 122 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 UA74_25000 e0a8ab374cb91c29353f5c877960fa82 123 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 19 123 9.7E-34 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 SUPERFAMILY SSF50129 4 98 1.04E-34 T 12-10-2018 IPR011032 GroES-like superfamily UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 PRINTS PR00297 10kDa chaperonin signature 28 49 1.1E-30 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 PRINTS PR00297 10kDa chaperonin signature 6 21 1.1E-30 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 PRINTS PR00297 10kDa chaperonin signature 63 75 1.1E-30 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 PRINTS PR00297 10kDa chaperonin signature 84 97 1.1E-30 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 Gene3D G3DSA:2.30.33.40 2 98 1.0E-38 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 SMART SM00883 5 97 4.2E-55 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 Pfam PF00166 Chaperonin 10 Kd subunit 5 97 2.8E-35 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 Hamap MF_00580 10 kDa chaperonin [groS]. 5 98 26.046 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_27915 cbfbb9c9c100d4ee5d60ff18aa807eb6 98 ProSitePatterns PS00681 Chaperonins cpn10 signature. 6 30 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 UA74_03000 36ebb32901aa50e8b7cc8fddb6755740 104 Pfam PF00467 KOW motif 5 36 3.7E-8 T 12-10-2018 IPR005824 KOW UA74_03000 36ebb32901aa50e8b7cc8fddb6755740 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 104 2.0E-23 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03000 36ebb32901aa50e8b7cc8fddb6755740 104 SUPERFAMILY SSF50104 1 99 2.37E-29 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily UA74_03000 36ebb32901aa50e8b7cc8fddb6755740 104 SMART SM00739 2 29 1.7E-4 T 12-10-2018 IPR005824 KOW UA74_03000 36ebb32901aa50e8b7cc8fddb6755740 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 104 6.2E-36 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03000 36ebb32901aa50e8b7cc8fddb6755740 104 Gene3D G3DSA:2.30.30.30 1 103 9.5E-34 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 UA74_03000 36ebb32901aa50e8b7cc8fddb6755740 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 98 20.703 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03000 36ebb32901aa50e8b7cc8fddb6755740 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_01975 fdfa601dbd8bf79bdcc09398146fb37d 421 Pfam PF01547 Bacterial extracellular solute-binding protein 55 337 2.5E-41 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_01975 fdfa601dbd8bf79bdcc09398146fb37d 421 Gene3D G3DSA:3.40.190.10 53 376 1.7E-74 T 12-10-2018 UA74_01975 fdfa601dbd8bf79bdcc09398146fb37d 421 SUPERFAMILY SSF53850 19 419 1.2E-71 T 12-10-2018 UA74_01975 fdfa601dbd8bf79bdcc09398146fb37d 421 Gene3D G3DSA:3.40.190.10 147 413 1.7E-74 T 12-10-2018 UA74_08895 2584d52f8bddcf48058d7cc34e3d362b 817 SUPERFAMILY SSF51445 292 635 5.76E-103 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_08895 2584d52f8bddcf48058d7cc34e3d362b 817 Gene3D G3DSA:2.60.40.10 192 294 3.6E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_08895 2584d52f8bddcf48058d7cc34e3d362b 817 Gene3D G3DSA:2.60.120.260 2 191 7.3E-60 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_08895 2584d52f8bddcf48058d7cc34e3d362b 817 SUPERFAMILY SSF49303 191 295 7.91E-17 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily UA74_08895 2584d52f8bddcf48058d7cc34e3d362b 817 SUPERFAMILY SSF49303 732 799 5.61E-5 T 12-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily UA74_08895 2584d52f8bddcf48058d7cc34e3d362b 817 SUPERFAMILY SSF49785 2 187 1.98E-52 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_08895 2584d52f8bddcf48058d7cc34e3d362b 817 Pfam PF00703 Glycosyl hydrolases family 2 205 295 1.9E-5 T 12-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 UA74_08895 2584d52f8bddcf48058d7cc34e3d362b 817 Gene3D G3DSA:3.20.20.80 295 634 1.4E-115 T 12-10-2018 UA74_23735 bd98bcbad11a55d6855c82746c78a14c 427 SUPERFAMILY SSF47819 224 334 6.11E-25 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 UA74_23735 bd98bcbad11a55d6855c82746c78a14c 427 Pfam PF01612 3'-5' exonuclease 39 203 9.5E-31 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 UA74_23735 bd98bcbad11a55d6855c82746c78a14c 427 SMART SM00341 243 323 3.9E-20 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_23735 bd98bcbad11a55d6855c82746c78a14c 427 Gene3D G3DSA:1.10.150.80 332 423 1.7E-28 T 12-10-2018 UA74_23735 bd98bcbad11a55d6855c82746c78a14c 427 SMART SM00474 37 204 7.2E-35 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 UA74_23735 bd98bcbad11a55d6855c82746c78a14c 427 Gene3D G3DSA:1.10.150.80 228 325 1.4E-25 T 12-10-2018 UA74_23735 bd98bcbad11a55d6855c82746c78a14c 427 Pfam PF00570 HRDC domain 247 312 1.2E-13 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_23735 bd98bcbad11a55d6855c82746c78a14c 427 Gene3D G3DSA:3.30.420.10 23 224 2.9E-68 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_23735 bd98bcbad11a55d6855c82746c78a14c 427 SUPERFAMILY SSF53098 27 241 1.67E-51 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 55 73 1.7E-32 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 99 116 1.7E-32 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 267 285 1.7E-32 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 298 317 1.7E-32 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 86 99 1.7E-32 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00690 Adhesin family signature 214 235 1.7E-32 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 Gene3D G3DSA:3.40.50.1980 200 333 4.1E-40 T 12-10-2018 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 Gene3D G3DSA:3.40.50.1980 54 199 1.1E-34 T 12-10-2018 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 Pfam PF01297 Zinc-uptake complex component A periplasmic 58 329 3.7E-57 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 99 118 9.8E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 55 76 9.8E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 156 175 9.8E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 263 280 9.8E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 80 98 9.8E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 PRINTS PR00691 Adhesin B signature 214 231 9.8E-18 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_11270 d5bd2ab474bc8d0dfe3f954adfb035b7 333 SUPERFAMILY SSF53807 52 332 4.17E-61 T 12-10-2018 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 SMART SM00387 367 476 2.0E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_20680 602396e77255dfb227e50c56db51a6a5 479 SMART SM00304 200 252 1.2E-15 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 Gene3D G3DSA:1.10.287.130 255 332 2.2E-16 T 12-10-2018 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 Pfam PF00672 HAMP domain 200 248 1.4E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 SMART SM00388 260 327 1.1E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 Gene3D G3DSA:3.30.565.10 333 478 4.3E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_20680 602396e77255dfb227e50c56db51a6a5 479 Gene3D G3DSA:1.20.1480.50 161 254 1.3E-11 T 12-10-2018 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 475 2.1E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_20680 602396e77255dfb227e50c56db51a6a5 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 262 327 6.4E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 SUPERFAMILY SSF55874 316 474 5.11E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_20680 602396e77255dfb227e50c56db51a6a5 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 5.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 5.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 5.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 5.5E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 SUPERFAMILY SSF158472 200 249 2.22E-9 T 12-10-2018 UA74_20680 602396e77255dfb227e50c56db51a6a5 479 SUPERFAMILY SSF47384 244 327 5.3E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_23105 e167eb190052c5f302f985895ab9b0ca 882 Gene3D G3DSA:3.40.50.300 600 756 7.2E-9 T 12-10-2018 UA74_23105 e167eb190052c5f302f985895ab9b0ca 882 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 358 755 1.1E-45 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core UA74_23105 e167eb190052c5f302f985895ab9b0ca 882 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 71 280 2.4E-17 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain UA74_23105 e167eb190052c5f302f985895ab9b0ca 882 SMART SM00487 335 582 0.0067 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_23105 e167eb190052c5f302f985895ab9b0ca 882 SUPERFAMILY SSF52540 355 748 2.73E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_23105 e167eb190052c5f302f985895ab9b0ca 882 Gene3D G3DSA:1.10.3210.30 51 329 2.0E-57 T 12-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily UA74_13125 f372b455818b8f64cddae4e75219253f 509 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 47 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_13125 f372b455818b8f64cddae4e75219253f 509 Pfam PF00069 Protein kinase domain 18 267 2.7E-48 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_13125 f372b455818b8f64cddae4e75219253f 509 Gene3D G3DSA:3.30.200.20 7 101 1.3E-26 T 12-10-2018 UA74_13125 f372b455818b8f64cddae4e75219253f 509 SMART SM00220 18 272 1.1E-53 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_13125 f372b455818b8f64cddae4e75219253f 509 SUPERFAMILY SSF56112 9 270 8.23E-66 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_13125 f372b455818b8f64cddae4e75219253f 509 Gene3D G3DSA:1.10.510.10 105 275 3.4E-42 T 12-10-2018 UA74_13125 f372b455818b8f64cddae4e75219253f 509 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 141 153 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_13790 aa0ebb87f6f671dd85cebcc18264b03b 211 Pfam PF01930 Domain of unknown function DUF83 15 191 6.4E-25 T 12-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 UA74_13790 aa0ebb87f6f671dd85cebcc18264b03b 211 Gene3D G3DSA:3.90.320.10 5 191 3.5E-11 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal UA74_13790 aa0ebb87f6f671dd85cebcc18264b03b 211 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 13 191 3.7E-26 T 12-10-2018 IPR013343 CRISPR-associated protein Cas4 UA74_30120 ee2dd62966ce707046a78224c6026ae7 398 Pfam PF00990 Diguanylate cyclase, GGDEF domain 231 393 4.2E-41 T 12-10-2018 IPR000160 GGDEF domain UA74_30120 ee2dd62966ce707046a78224c6026ae7 398 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 229 397 1.7E-44 T 12-10-2018 IPR000160 GGDEF domain UA74_30120 ee2dd62966ce707046a78224c6026ae7 398 SMART SM00267 220 398 1.5E-45 T 12-10-2018 IPR000160 GGDEF domain UA74_30120 ee2dd62966ce707046a78224c6026ae7 398 Gene3D G3DSA:3.30.70.270 226 398 4.0E-49 T 12-10-2018 UA74_30120 ee2dd62966ce707046a78224c6026ae7 398 SUPERFAMILY SSF55073 237 396 4.32E-41 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_02680 49653266967d347bdef3d30bded874eb 426 Gene3D G3DSA:2.40.420.20 345 423 5.4E-11 T 12-10-2018 UA74_02680 49653266967d347bdef3d30bded874eb 426 Pfam PF01471 Putative peptidoglycan binding domain 195 241 4.4E-10 T 12-10-2018 IPR002477 Peptidoglycan binding-like UA74_02680 49653266967d347bdef3d30bded874eb 426 Gene3D G3DSA:1.10.101.10 184 244 6.5E-9 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UA74_02680 49653266967d347bdef3d30bded874eb 426 SUPERFAMILY SSF47090 184 242 1.24E-10 T 12-10-2018 IPR036365 PGBD-like superfamily UA74_10225 f6719cf2c5ab9b985f37983be7601b39 589 Pfam PF02384 N-6 DNA Methylase 143 399 1.8E-22 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_10225 f6719cf2c5ab9b985f37983be7601b39 589 SUPERFAMILY SSF53335 131 418 3.3E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_10225 f6719cf2c5ab9b985f37983be7601b39 589 Gene3D G3DSA:3.40.50.150 129 395 5.6E-26 T 12-10-2018 UA74_05145 f57a10b1c9a7351817a23fad2c27e493 472 Pfam PF00668 Condensation domain 5 445 1.3E-59 T 12-10-2018 IPR001242 Condensation domain UA74_05145 f57a10b1c9a7351817a23fad2c27e493 472 SUPERFAMILY SSF52777 10 184 8.15E-37 T 12-10-2018 UA74_05145 f57a10b1c9a7351817a23fad2c27e493 472 SUPERFAMILY SSF52777 200 442 6.67E-29 T 12-10-2018 UA74_05145 f57a10b1c9a7351817a23fad2c27e493 472 Gene3D G3DSA:3.30.559.30 199 444 2.3E-34 T 12-10-2018 UA74_05145 f57a10b1c9a7351817a23fad2c27e493 472 Gene3D G3DSA:3.30.559.10 2 198 5.1E-45 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_13260 805d170d248ae1cb6596c06882887fc3 249 Pfam PF12697 Alpha/beta hydrolase family 14 237 5.7E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_13260 805d170d248ae1cb6596c06882887fc3 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.6E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_13260 805d170d248ae1cb6596c06882887fc3 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 1.6E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_13260 805d170d248ae1cb6596c06882887fc3 249 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 1.6E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_13260 805d170d248ae1cb6596c06882887fc3 249 SUPERFAMILY SSF53474 1 245 1.09E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_13260 805d170d248ae1cb6596c06882887fc3 249 Gene3D G3DSA:3.40.50.1820 1 246 1.4E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15625 4ddf5b8b14b85e737e88f56581b03b8c 120 Pfam PF02467 Transcription factor WhiB 52 97 2.7E-11 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain UA74_04455 bd1cef80ea584336450473386659afb8 282 Pfam PF03641 Possible lysine decarboxylase 141 269 6.9E-31 T 12-10-2018 IPR031100 LOG family UA74_04455 bd1cef80ea584336450473386659afb8 282 Gene3D G3DSA:3.40.50.450 70 282 6.7E-67 T 12-10-2018 UA74_04455 bd1cef80ea584336450473386659afb8 282 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 98 271 4.3E-42 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG UA74_04455 bd1cef80ea584336450473386659afb8 282 SUPERFAMILY SSF102405 69 270 6.72E-61 T 12-10-2018 UA74_25745 abc499c2337cb036c565a77b6025f9ff 322 PIRSF PIRSF005303 9 319 2.2E-87 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 UA74_25745 abc499c2337cb036c565a77b6025f9ff 322 Gene3D G3DSA:3.90.650.10 157 319 1.2E-47 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UA74_25745 abc499c2337cb036c565a77b6025f9ff 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 15 318 4.0E-82 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 UA74_25745 abc499c2337cb036c565a77b6025f9ff 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 39 148 2.7E-20 T 12-10-2018 IPR016188 PurM-like, N-terminal domain UA74_25745 abc499c2337cb036c565a77b6025f9ff 322 Gene3D G3DSA:3.30.1330.10 10 150 9.1E-45 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UA74_25745 abc499c2337cb036c565a77b6025f9ff 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 14 319 26.812 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 UA74_25745 abc499c2337cb036c565a77b6025f9ff 322 SUPERFAMILY SSF56042 155 305 9.63E-30 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UA74_25745 abc499c2337cb036c565a77b6025f9ff 322 SUPERFAMILY SSF55326 12 148 8.52E-34 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UA74_00960 46572034fdb105726bc2e30c6e8169fd 394 SUPERFAMILY SSF50939 19 387 7.57E-49 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_00960 46572034fdb105726bc2e30c6e8169fd 394 Pfam PF13088 BNR repeat-like domain 34 369 4.0E-61 T 12-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_00960 46572034fdb105726bc2e30c6e8169fd 394 Gene3D G3DSA:2.120.10.10 19 248 1.9E-35 T 12-10-2018 UA74_03425 3d13426ff3bc0638b8563c78705d84a3 434 PRINTS PR00095 Anthranilate synthase component I signature 377 391 3.1E-10 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_03425 3d13426ff3bc0638b8563c78705d84a3 434 PRINTS PR00095 Anthranilate synthase component I signature 268 281 3.1E-10 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_03425 3d13426ff3bc0638b8563c78705d84a3 434 PRINTS PR00095 Anthranilate synthase component I signature 362 376 3.1E-10 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_03425 3d13426ff3bc0638b8563c78705d84a3 434 PRINTS PR00095 Anthranilate synthase component I signature 282 295 3.1E-10 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_03425 3d13426ff3bc0638b8563c78705d84a3 434 Pfam PF00425 chorismate binding enzyme 169 424 3.6E-75 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal UA74_03425 3d13426ff3bc0638b8563c78705d84a3 434 SUPERFAMILY SSF56322 59 433 7.85E-93 T 12-10-2018 IPR005801 ADC synthase GO:0009058 UA74_03425 3d13426ff3bc0638b8563c78705d84a3 434 Gene3D G3DSA:3.60.120.10 73 434 1.1E-102 T 12-10-2018 IPR005801 ADC synthase GO:0009058 UA74_22955 1776e8f3c2aff3cbcce4ba0ae0f80264 142 SMART SM00960 10 100 1.7E-29 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain UA74_22955 1776e8f3c2aff3cbcce4ba0ae0f80264 142 SUPERFAMILY SSF103196 2 129 2.44E-35 T 12-10-2018 UA74_22955 1776e8f3c2aff3cbcce4ba0ae0f80264 142 Gene3D G3DSA:3.30.450.30 5 131 6.5E-40 T 12-10-2018 UA74_22955 1776e8f3c2aff3cbcce4ba0ae0f80264 142 Pfam PF03259 Roadblock/LC7 domain 9 100 2.2E-25 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain UA74_08215 6116ebe642212de3459de69205bda507 480 SUPERFAMILY SSF52540 161 346 1.68E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08215 6116ebe642212de3459de69205bda507 480 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 UA74_08215 6116ebe642212de3459de69205bda507 480 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 369 432 6.3E-25 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 UA74_08215 6116ebe642212de3459de69205bda507 480 SUPERFAMILY SSF82051 4 157 1.44E-48 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily UA74_08215 6116ebe642212de3459de69205bda507 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 5.9E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_08215 6116ebe642212de3459de69205bda507 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 5.9E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_08215 6116ebe642212de3459de69205bda507 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 5.9E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_08215 6116ebe642212de3459de69205bda507 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 5.9E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_08215 6116ebe642212de3459de69205bda507 480 Gene3D G3DSA:2.70.210.12 1 158 1.4E-52 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily UA74_08215 6116ebe642212de3459de69205bda507 480 Pfam PF01018 GTP1/OBG 5 157 2.5E-53 T 12-10-2018 IPR006169 GTP1/OBG domain UA74_08215 6116ebe642212de3459de69205bda507 480 Gene3D G3DSA:3.40.50.300 160 348 3.6E-48 T 12-10-2018 UA74_08215 6116ebe642212de3459de69205bda507 480 Hamap MF_01454 GTPase Obg [obg]. 3 335 45.174 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 UA74_08215 6116ebe642212de3459de69205bda507 480 Gene3D G3DSA:2.40.240.60 359 434 8.4E-20 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily UA74_08215 6116ebe642212de3459de69205bda507 480 SUPERFAMILY SSF102741 367 433 5.89E-20 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily UA74_08215 6116ebe642212de3459de69205bda507 480 Pfam PF09269 Domain of unknown function (DUF1967) 361 431 3.0E-24 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 UA74_08215 6116ebe642212de3459de69205bda507 480 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 333 5.6E-127 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 UA74_08215 6116ebe642212de3459de69205bda507 480 Pfam PF01926 50S ribosome-binding GTPase 161 288 5.6E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_10990 de073335b424d037b0ca931b79c06014 111 SUPERFAMILY SSF54909 2 105 2.57E-42 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_10990 de073335b424d037b0ca931b79c06014 111 Gene3D G3DSA:3.30.70.1090 1 107 2.7E-41 T 12-10-2018 IPR038474 Polyketide synthesis cyclase superfamily UA74_10990 de073335b424d037b0ca931b79c06014 111 ProDom PD012644 CYCLASE POLYKETIDE II SYNTHESIS ORF SYNTHASE JADI BIOSYNTHESIS ANTIBIOTIC CYCLASE-LIKE 2 103 1.0E-41 T 12-10-2018 IPR006765 Polyketide synthesis cyclase GO:0030639 UA74_10990 de073335b424d037b0ca931b79c06014 111 Pfam PF04673 Polyketide synthesis cyclase 2 104 2.5E-41 T 12-10-2018 IPR006765 Polyketide synthesis cyclase GO:0030639 UA74_23130 a8a9b63645da3b9b1b5ddf584323c26b 378 Pfam PF11991 Tryptophan dimethylallyltransferase 79 259 8.7E-16 T 12-10-2018 IPR017795 Aromatic prenyltransferase, DMATS-type GO:0009820|GO:0016765 UA74_19125 9f9c279c55caed2f47c059f296d2e4d6 80 SUPERFAMILY SSF89796 3 65 7.19E-12 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily UA74_19125 9f9c279c55caed2f47c059f296d2e4d6 80 Gene3D G3DSA:3.30.60.110 16 49 7.3E-9 T 12-10-2018 UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 236 248 2.2E-11 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 83 98 2.2E-11 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 147 161 2.2E-11 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 Gene3D G3DSA:2.40.10.10 68 278 7.4E-69 T 12-10-2018 UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 SMART SM00020 55 282 5.2E-76 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 237 248 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 SUPERFAMILY SSF50494 33 286 4.61E-66 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 Pfam PF00089 Trypsin 56 280 5.1E-56 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 Gene3D G3DSA:2.40.10.10 56 276 7.4E-69 T 12-10-2018 UA74_09130 009e36a9195fe2d89abdf3f7aea056ab 288 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 93 98 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 UA74_03690 e9be77fa2002ee7ea975be197a0609b8 489 PIRSF PIRSF002746 2 489 1.7E-149 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_03690 e9be77fa2002ee7ea975be197a0609b8 489 Pfam PF02447 GntP family permease 264 485 5.2E-63 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_03690 e9be77fa2002ee7ea975be197a0609b8 489 Pfam PF02447 GntP family permease 8 206 2.0E-66 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_20330 ce8221e14518204c57fb739ca40faab2 343 Gene3D G3DSA:1.10.3470.10 17 340 3.3E-90 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_20330 ce8221e14518204c57fb739ca40faab2 343 Pfam PF01032 FecCD transport family 31 337 3.5E-85 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_20330 ce8221e14518204c57fb739ca40faab2 343 SUPERFAMILY SSF81345 16 337 1.44E-75 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_27145 aa8cfbe21945ddef723103056a54eb6f 410 Gene3D G3DSA:3.30.420.40 215 388 7.0E-88 T 12-10-2018 UA74_27145 aa8cfbe21945ddef723103056a54eb6f 410 SUPERFAMILY SSF46785 24 87 1.05E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_27145 aa8cfbe21945ddef723103056a54eb6f 410 SUPERFAMILY SSF53067 94 403 1.24E-58 T 12-10-2018 UA74_27145 aa8cfbe21945ddef723103056a54eb6f 410 Gene3D G3DSA:1.10.10.10 17 88 1.2E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27145 aa8cfbe21945ddef723103056a54eb6f 410 ProSitePatterns PS01125 ROK family signature. 225 252 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_27145 aa8cfbe21945ddef723103056a54eb6f 410 Pfam PF00480 ROK family 95 402 1.0E-58 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_27145 aa8cfbe21945ddef723103056a54eb6f 410 Gene3D G3DSA:3.30.420.40 99 398 7.0E-88 T 12-10-2018 UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 Gene3D G3DSA:3.50.50.60 67 395 1.8E-125 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 Pfam PF01494 FAD binding domain 66 396 3.1E-86 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 SUPERFAMILY SSF51905 66 410 5.26E-67 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 Gene3D G3DSA:3.30.70.2450 235 321 1.8E-125 T 12-10-2018 UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 Gene3D G3DSA:3.40.30.120 443 539 3.6E-26 T 12-10-2018 UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 347 363 3.7E-44 T 12-10-2018 UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 206 221 3.7E-44 T 12-10-2018 UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 365 383 3.7E-44 T 12-10-2018 UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 332 347 3.7E-44 T 12-10-2018 UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 67 89 3.7E-44 T 12-10-2018 UA74_15395 e636571e04cfb06a6180b14f0e2e5b3e 541 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 383 399 3.7E-44 T 12-10-2018 UA74_13745 9fc57ae6cf29c62456677582655c3546 407 SMART SM00530 15 70 1.9E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_13745 9fc57ae6cf29c62456677582655c3546 407 Gene3D G3DSA:1.10.260.40 7 73 8.6E-8 T 12-10-2018 UA74_13745 9fc57ae6cf29c62456677582655c3546 407 Pfam PF13560 Helix-turn-helix domain 12 66 2.1E-11 T 12-10-2018 UA74_13745 9fc57ae6cf29c62456677582655c3546 407 SUPERFAMILY SSF47413 7 66 2.07E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 193 210 1.4E-43 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 235 253 1.4E-43 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 1.4E-43 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 89 110 1.4E-43 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 153 173 1.4E-43 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_03975 db9f7200b33afc0a9f5a9801276f38f1 289 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 130 152 1.4E-43 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_03975 db9f7200b33afc0a9f5a9801276f38f1 289 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 14 253 1.3E-73 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_03975 db9f7200b33afc0a9f5a9801276f38f1 289 Gene3D G3DSA:2.120.10.30 1 284 8.7E-94 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_03975 db9f7200b33afc0a9f5a9801276f38f1 289 SUPERFAMILY SSF63829 11 282 2.13E-64 T 12-10-2018 UA74_11250 561d3155fa6ab6fcc7578f8966149766 242 SUPERFAMILY SSF51735 2 194 1.19E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_11250 561d3155fa6ab6fcc7578f8966149766 242 Gene3D G3DSA:3.40.50.720 1 228 1.4E-32 T 12-10-2018 UA74_11250 561d3155fa6ab6fcc7578f8966149766 242 Pfam PF00106 short chain dehydrogenase 3 183 3.5E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_27765 deff853efd3d798c659833a09a875e15 101 Gene3D G3DSA:1.20.59.10 13 97 5.1E-28 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UA74_27765 deff853efd3d798c659833a09a875e15 101 SUPERFAMILY SSF48600 17 79 4.12E-14 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UA74_27765 deff853efd3d798c659833a09a875e15 101 Pfam PF01817 Chorismate mutase type II 25 84 8.5E-11 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UA74_27765 deff853efd3d798c659833a09a875e15 101 SMART SM00830 25 87 7.4E-8 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UA74_27765 deff853efd3d798c659833a09a875e15 101 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 20 93 2.6E-30 T 12-10-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 SUPERFAMILY SSF53795 243 605 6.18E-154 T 12-10-2018 UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 SUPERFAMILY SSF68923 12 242 7.32E-97 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 243 605 6.0E-171 T 12-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 22 239 8.1E-100 T 12-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 Gene3D G3DSA:3.90.228.20 243 601 7.1E-274 T 12-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 267 275 - T 12-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 PIRSF PIRSF001348 2 606 1.3E-282 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 Gene3D G3DSA:2.170.8.10 57 399 7.1E-274 T 12-10-2018 UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 606 50.005 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 UA74_29845 25ec9c7365d31374915afba3fc166ec6 606 Gene3D G3DSA:3.40.449.10 21 242 7.1E-274 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UA74_26470 622e32e1af71395c461a1cd2dd23f9a0 338 SUPERFAMILY SSF52540 117 328 7.99E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26470 622e32e1af71395c461a1cd2dd23f9a0 338 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 74 327 7.9E-41 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 UA74_26470 622e32e1af71395c461a1cd2dd23f9a0 338 Gene3D G3DSA:3.40.50.300 102 267 3.1E-35 T 12-10-2018 UA74_26470 622e32e1af71395c461a1cd2dd23f9a0 338 Pfam PF03193 RsgA GTPase 99 267 4.4E-40 T 12-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 UA74_08695 f032dbc22b677437adf17cd506d772e9 344 Gene3D G3DSA:3.40.718.10 1 329 7.2E-110 T 12-10-2018 UA74_08695 f032dbc22b677437adf17cd506d772e9 344 SUPERFAMILY SSF53659 4 330 4.96E-90 T 12-10-2018 UA74_08695 f032dbc22b677437adf17cd506d772e9 344 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 34 323 4.9E-87 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 UA74_08695 f032dbc22b677437adf17cd506d772e9 344 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 328 2.0E-91 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 UA74_27270 1a07934013e28912af7f74ca1463bb44 277 Gene3D G3DSA:3.20.20.100 5 276 5.7E-81 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_27270 1a07934013e28912af7f74ca1463bb44 277 Pfam PF00248 Aldo/keto reductase family 8 271 5.0E-61 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_27270 1a07934013e28912af7f74ca1463bb44 277 PRINTS PR00069 Aldo-keto reductase signature 38 62 5.9E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_27270 1a07934013e28912af7f74ca1463bb44 277 PRINTS PR00069 Aldo-keto reductase signature 103 121 5.9E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_27270 1a07934013e28912af7f74ca1463bb44 277 PRINTS PR00069 Aldo-keto reductase signature 134 151 5.9E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_27270 1a07934013e28912af7f74ca1463bb44 277 PRINTS PR00069 Aldo-keto reductase signature 205 229 5.9E-9 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_27270 1a07934013e28912af7f74ca1463bb44 277 SUPERFAMILY SSF51430 6 271 7.33E-72 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_01830 2f78e16e0822a57fcaf3a6f47f91580d 162 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 2 155 1.2E-54 T 12-10-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00260+2.3.1.178 UA74_01830 2f78e16e0822a57fcaf3a6f47f91580d 162 Pfam PF00583 Acetyltransferase (GNAT) family 35 119 2.6E-13 T 12-10-2018 IPR000182 GNAT domain UA74_01830 2f78e16e0822a57fcaf3a6f47f91580d 162 Gene3D G3DSA:3.40.630.30 1 159 2.5E-47 T 12-10-2018 UA74_01830 2f78e16e0822a57fcaf3a6f47f91580d 162 SUPERFAMILY SSF55729 2 121 4.36E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_21100 45c177ef99d175d9d2404e201238a8e9 603 Pfam PF02652 L-lactate permease 15 292 5.2E-74 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 UA74_21100 45c177ef99d175d9d2404e201238a8e9 603 Pfam PF02652 L-lactate permease 335 593 2.3E-66 T 12-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 UA74_13465 98da2031572e6d9ee7893cfd013f10c0 426 Gene3D G3DSA:1.20.1250.20 18 204 4.3E-23 T 12-10-2018 UA74_13465 98da2031572e6d9ee7893cfd013f10c0 426 SUPERFAMILY SSF103473 18 392 3.66E-50 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_13465 98da2031572e6d9ee7893cfd013f10c0 426 Gene3D G3DSA:1.20.1250.20 214 403 2.7E-21 T 12-10-2018 UA74_13465 98da2031572e6d9ee7893cfd013f10c0 426 Pfam PF07690 Major Facilitator Superfamily 227 406 3.3E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_13465 98da2031572e6d9ee7893cfd013f10c0 426 Pfam PF07690 Major Facilitator Superfamily 26 220 2.0E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_26655 8bed9ac0c4f67b00ce59b88e505608b4 383 SUPERFAMILY SSF53756 15 375 4.66E-68 T 12-10-2018 UA74_26655 8bed9ac0c4f67b00ce59b88e505608b4 383 Pfam PF13439 Glycosyltransferase Family 4 20 180 1.3E-20 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_26655 8bed9ac0c4f67b00ce59b88e505608b4 383 Gene3D G3DSA:3.40.50.2000 192 375 8.1E-36 T 12-10-2018 UA74_26655 8bed9ac0c4f67b00ce59b88e505608b4 383 Gene3D G3DSA:3.40.50.2000 8 191 1.8E-19 T 12-10-2018 UA74_26655 8bed9ac0c4f67b00ce59b88e505608b4 383 Pfam PF00534 Glycosyl transferases group 1 199 354 2.4E-20 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_08570 1f1fbb8a6aa5437a3eef0c399c6b81cf 296 Gene3D G3DSA:1.10.3720.10 51 264 1.0E-42 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08570 1f1fbb8a6aa5437a3eef0c399c6b81cf 296 SUPERFAMILY SSF161098 62 245 5.1E-36 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08570 1f1fbb8a6aa5437a3eef0c399c6b81cf 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 260 1.1E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_08570 1f1fbb8a6aa5437a3eef0c399c6b81cf 296 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 62 151 8.2E-16 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UA74_13515 89201df0ac755b96f25aa8b9be72d8ca 389 Gene3D G3DSA:1.20.140.10 237 383 2.1E-50 T 12-10-2018 UA74_13515 89201df0ac755b96f25aa8b9be72d8ca 389 SUPERFAMILY SSF47203 227 381 7.89E-52 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_13515 89201df0ac755b96f25aa8b9be72d8ca 389 Gene3D G3DSA:1.10.540.10 1 122 2.5E-23 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_13515 89201df0ac755b96f25aa8b9be72d8ca 389 Gene3D G3DSA:2.40.110.10 124 236 2.1E-34 T 12-10-2018 UA74_13515 89201df0ac755b96f25aa8b9be72d8ca 389 SUPERFAMILY SSF56645 1 241 7.07E-62 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_13515 89201df0ac755b96f25aa8b9be72d8ca 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 216 1.4E-19 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UA74_13515 89201df0ac755b96f25aa8b9be72d8ca 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 6.6E-18 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UA74_13515 89201df0ac755b96f25aa8b9be72d8ca 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 8.1E-44 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 Gene3D G3DSA:3.30.420.10 1 159 6.8E-48 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 2.5E-54 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 44.964 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 12-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 154 2.2E-33 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 5.7E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 5.7E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 5.7E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 5.7E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 5.7E-37 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 UA74_11075 c7d75bb0907a0d7e66e5b62dd6866d3f 293 SUPERFAMILY SSF53098 2 157 2.05E-43 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_05935 2742f79084947ce6aa9feac37dcd52f0 392 Gene3D G3DSA:3.30.920.50 240 346 1.7E-97 T 12-10-2018 UA74_05935 2742f79084947ce6aa9feac37dcd52f0 392 Pfam PF16483 Beta-1,3-glucanase 46 389 1.2E-96 T 12-10-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 UA74_05935 2742f79084947ce6aa9feac37dcd52f0 392 Gene3D G3DSA:2.60.110.10 51 371 1.7E-97 T 12-10-2018 IPR037176 Osmotin/thaumatin-like superfamily UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 Gene3D G3DSA:2.60.40.1730 18 201 3.3E-25 T 12-10-2018 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 Gene3D G3DSA:1.10.390.60 210 454 1.9E-70 T 12-10-2018 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 SUPERFAMILY SSF55486 216 458 1.14E-76 T 12-10-2018 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 SUPERFAMILY SSF63737 6 201 1.29E-39 T 12-10-2018 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 Pfam PF11838 ERAP1-like C-terminal domain 534 840 5.6E-61 T 12-10-2018 IPR024571 ERAP1-like C-terminal domain UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 301 316 3.1E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 184 199 3.1E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 137 152 3.1E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 267 277 3.1E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 320 332 3.1E-22 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 Pfam PF01433 Peptidase family M1 domain 230 449 2.7E-58 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 UA74_07945 6d6359c82248fd71497b1c1c44cd2d59 852 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 848 0.0 T 12-10-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2 UA74_19320 fddc78f332afebdf4ec95a383057bcaf 571 Gene3D G3DSA:3.50.30.80 371 525 7.4E-50 T 12-10-2018 UA74_19320 fddc78f332afebdf4ec95a383057bcaf 571 Pfam PF00920 Dehydratase family 36 552 3.7E-168 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_19320 fddc78f332afebdf4ec95a383057bcaf 571 SUPERFAMILY SSF143975 3 368 1.44E-111 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_19320 fddc78f332afebdf4ec95a383057bcaf 571 SUPERFAMILY SSF52016 371 558 3.06E-55 T 12-10-2018 UA74_19320 fddc78f332afebdf4ec95a383057bcaf 571 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_20430 971c058cf0f9506348d6fb72ad8a5ffe 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 3.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_20430 971c058cf0f9506348d6fb72ad8a5ffe 202 Gene3D G3DSA:1.10.357.10 3 202 2.0E-50 T 12-10-2018 UA74_20430 971c058cf0f9506348d6fb72ad8a5ffe 202 SUPERFAMILY SSF46689 2 77 2.98E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_20430 971c058cf0f9506348d6fb72ad8a5ffe 202 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 82 195 2.5E-26 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal UA74_20430 971c058cf0f9506348d6fb72ad8a5ffe 202 SUPERFAMILY SSF48498 82 195 1.42E-20 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_01340 db47741d09f3b42c0311f577c4a27599 310 SUPERFAMILY SSF46689 15 87 2.33E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_01340 db47741d09f3b42c0311f577c4a27599 310 Gene3D G3DSA:3.40.50.10490 108 292 3.9E-47 T 12-10-2018 UA74_01340 db47741d09f3b42c0311f577c4a27599 310 SUPERFAMILY SSF53697 107 289 4.45E-43 T 12-10-2018 UA74_01340 db47741d09f3b42c0311f577c4a27599 310 Pfam PF01418 Helix-turn-helix domain, rpiR family 17 87 7.7E-20 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UA74_01340 db47741d09f3b42c0311f577c4a27599 310 Pfam PF01380 SIS domain 142 269 1.8E-26 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UA74_01340 db47741d09f3b42c0311f577c4a27599 310 Gene3D G3DSA:1.10.10.10 9 92 1.4E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_01535 072c081fc4f51692f7e8b1e663bacae6 386 Pfam PF09179 TilS substrate binding domain 292 357 2.9E-12 T 12-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UA74_01535 072c081fc4f51692f7e8b1e663bacae6 386 Gene3D G3DSA:3.40.50.620 61 275 2.1E-57 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_01535 072c081fc4f51692f7e8b1e663bacae6 386 Pfam PF01171 PP-loop family 68 241 4.7E-31 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 UA74_01535 072c081fc4f51692f7e8b1e663bacae6 386 SUPERFAMILY SSF82829 254 356 1.57E-13 T 12-10-2018 UA74_01535 072c081fc4f51692f7e8b1e663bacae6 386 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 50 351 18.49 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UA74_01535 072c081fc4f51692f7e8b1e663bacae6 386 SUPERFAMILY SSF52402 68 273 1.62E-42 T 12-10-2018 UA74_01535 072c081fc4f51692f7e8b1e663bacae6 386 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 68 244 3.4E-37 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UA74_13490 123171f6e25810bd78a51c031999610a 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 32 1.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13490 123171f6e25810bd78a51c031999610a 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 130 1.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13490 123171f6e25810bd78a51c031999610a 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 82 1.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13490 123171f6e25810bd78a51c031999610a 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 111 1.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13490 123171f6e25810bd78a51c031999610a 204 Gene3D G3DSA:3.40.50.720 1 195 2.3E-37 T 12-10-2018 UA74_13490 123171f6e25810bd78a51c031999610a 204 Pfam PF00106 short chain dehydrogenase 1 135 8.1E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13490 123171f6e25810bd78a51c031999610a 204 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 79 107 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_13490 123171f6e25810bd78a51c031999610a 204 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 21 32 7.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13490 123171f6e25810bd78a51c031999610a 204 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 111 7.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13490 123171f6e25810bd78a51c031999610a 204 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 90 7.4E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13490 123171f6e25810bd78a51c031999610a 204 SUPERFAMILY SSF51735 1 172 1.08E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_02620 c575337dd1f45a3550f8fea3fe7051a1 547 Pfam PF00361 Proton-conducting membrane transporter 133 428 1.2E-62 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02620 c575337dd1f45a3550f8fea3fe7051a1 547 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 6.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02620 c575337dd1f45a3550f8fea3fe7051a1 547 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 246 270 6.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02620 c575337dd1f45a3550f8fea3fe7051a1 547 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 169 193 6.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02620 c575337dd1f45a3550f8fea3fe7051a1 547 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 386 412 6.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02620 c575337dd1f45a3550f8fea3fe7051a1 547 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 334 353 6.9E-36 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02620 c575337dd1f45a3550f8fea3fe7051a1 547 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 9 518 2.4E-170 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_22190 3ac80da70db735e434b437c8a4544b8f 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 7.8E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22190 3ac80da70db735e434b437c8a4544b8f 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 7.8E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22190 3ac80da70db735e434b437c8a4544b8f 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 7.8E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22190 3ac80da70db735e434b437c8a4544b8f 268 SUPERFAMILY SSF53474 1 259 1.08E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22190 3ac80da70db735e434b437c8a4544b8f 268 Gene3D G3DSA:3.40.50.1820 1 261 6.8E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22190 3ac80da70db735e434b437c8a4544b8f 268 Pfam PF00561 alpha/beta hydrolase fold 20 128 1.5E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05675 29130a588b7e80dd8aeace41dd0b5ec7 369 Gene3D G3DSA:3.40.640.10 2 244 4.1E-79 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_05675 29130a588b7e80dd8aeace41dd0b5ec7 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 363 2.5E-111 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_05675 29130a588b7e80dd8aeace41dd0b5ec7 369 Gene3D G3DSA:3.90.1150.10 247 367 3.8E-37 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_05675 29130a588b7e80dd8aeace41dd0b5ec7 369 PIRSF PIRSF000390 3 368 8.1E-100 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_05675 29130a588b7e80dd8aeace41dd0b5ec7 369 SUPERFAMILY SSF53383 8 366 4.81E-102 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 SUPERFAMILY SSF52980 963 1097 2.09E-7 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 Gene3D G3DSA:3.40.50.300 419 510 8.4E-16 T 12-10-2018 UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 Pfam PF13361 UvrD-like helicase C-terminal domain 423 516 5.4E-7 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 Pfam PF12705 PD-(D/E)XK nuclease superfamily 959 1113 1.3E-13 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 Gene3D G3DSA:3.40.50.300 24 205 6.5E-30 T 12-10-2018 UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 Pfam PF13361 UvrD-like helicase C-terminal domain 640 770 6.6E-16 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 SUPERFAMILY SSF52540 27 794 1.09E-104 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 Gene3D G3DSA:3.90.320.10 936 1097 3.9E-5 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 Gene3D G3DSA:3.40.50.300 240 381 3.8E-30 T 12-10-2018 UA74_04775 2e15f85c9a11cd6b9c7603edcffcd32b 1138 Pfam PF00580 UvrD/REP helicase N-terminal domain 28 345 3.1E-44 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 SUPERFAMILY SSF54814 259 323 4.25E-17 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 Gene3D G3DSA:3.30.1480.10 1 99 3.7E-34 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 SUPERFAMILY SSF50249 110 179 6.97E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_09235 71540629155a1ef5a7076d3161aa5202 349 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 340 26.119 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 Gene3D G3DSA:3.30.300.20 179 257 9.4E-31 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_09235 71540629155a1ef5a7076d3161aa5202 349 SMART SM00316 110 180 2.9E-5 T 12-10-2018 IPR022967 RNA-binding domain, S1 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 323 1.8E-105 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 SUPERFAMILY SSF69705 4 99 2.35E-30 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 SUPERFAMILY SSF54814 180 258 7.85E-27 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 Pfam PF13184 NusA-like KH domain 211 277 1.6E-24 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 Gene3D G3DSA:2.40.50.140 105 178 7.2E-29 T 12-10-2018 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 Pfam PF08529 NusA N-terminal domain 6 60 9.7E-9 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 Pfam PF08529 NusA N-terminal domain 68 100 1.4E-6 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 Gene3D G3DSA:3.30.300.20 258 329 1.7E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_09235 71540629155a1ef5a7076d3161aa5202 349 SMART SM00322 210 283 0.47 T 12-10-2018 IPR004087 K Homology domain GO:0003676 UA74_09235 71540629155a1ef5a7076d3161aa5202 349 SMART SM00322 284 338 1.2 T 12-10-2018 IPR004087 K Homology domain GO:0003676 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 SUPERFAMILY SSF51735 6 151 9.88E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 PIRSF PIRSF000102 1 318 1.2E-91 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 Gene3D G3DSA:3.40.50.720 2 153 4.0E-47 T 12-10-2018 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 149 167 2.1E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 179 192 2.1E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 6 30 2.1E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 31 55 2.1E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 PRINTS PR00086 L-lactate dehydrogenase signature 125 145 2.1E-24 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 SUPERFAMILY SSF56327 153 311 1.27E-45 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 151 8.6E-36 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 156 312 4.2E-18 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 UA74_27580 be0db59e4bcc19fe1d024a50c74064d7 318 Gene3D G3DSA:3.90.110.10 154 317 6.1E-51 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UA74_15555 039221f0d184524f7313f7b95411d11e 120 SMART SM00418 25 103 2.2E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_15555 039221f0d184524f7313f7b95411d11e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 3.5E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_15555 039221f0d184524f7313f7b95411d11e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 3.5E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_15555 039221f0d184524f7313f7b95411d11e 120 Gene3D G3DSA:1.10.10.10 18 112 2.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_15555 039221f0d184524f7313f7b95411d11e 120 SUPERFAMILY SSF46785 11 102 3.18E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_15555 039221f0d184524f7313f7b95411d11e 120 Pfam PF12840 Helix-turn-helix domain 25 79 7.2E-8 T 12-10-2018 UA74_00565 5f3d3be51ba7ba9fd334fe20b914573c 386 SMART SM00387 297 386 5.1E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_00565 5f3d3be51ba7ba9fd334fe20b914573c 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 300 384 3.9E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_00565 5f3d3be51ba7ba9fd334fe20b914573c 386 SMART SM00065 25 181 1.1E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 UA74_00565 5f3d3be51ba7ba9fd334fe20b914573c 386 Pfam PF13185 GAF domain 25 171 2.4E-12 T 12-10-2018 IPR003018 GAF domain GO:0005515 UA74_00565 5f3d3be51ba7ba9fd334fe20b914573c 386 SUPERFAMILY SSF55874 264 385 2.62E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_00565 5f3d3be51ba7ba9fd334fe20b914573c 386 Gene3D G3DSA:3.30.450.40 25 188 1.6E-21 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_00565 5f3d3be51ba7ba9fd334fe20b914573c 386 Gene3D G3DSA:3.30.565.10 267 385 4.2E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_00565 5f3d3be51ba7ba9fd334fe20b914573c 386 Pfam PF07730 Histidine kinase 188 254 1.2E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_00565 5f3d3be51ba7ba9fd334fe20b914573c 386 SUPERFAMILY SSF55781 25 181 2.18E-17 T 12-10-2018 UA74_12730 6b8915dca36ba81141a42852fc99aa56 226 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 34 214 5.3E-14 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_12730 6b8915dca36ba81141a42852fc99aa56 226 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 34 178 1.9E-21 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_12730 6b8915dca36ba81141a42852fc99aa56 226 SUPERFAMILY SSF109854 28 181 5.49E-15 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_12730 6b8915dca36ba81141a42852fc99aa56 226 Gene3D G3DSA:1.20.120.450 24 181 7.7E-20 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_29120 256c2cf1b3d0b0b175bfdbc5cb277554 266 SMART SM00862 146 220 3.6E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_29120 256c2cf1b3d0b0b175bfdbc5cb277554 266 Gene3D G3DSA:1.10.10.10 117 223 6.1E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_29120 256c2cf1b3d0b0b175bfdbc5cb277554 266 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 6.4E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_29120 256c2cf1b3d0b0b175bfdbc5cb277554 266 SUPERFAMILY SSF46894 121 221 1.47E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_29120 256c2cf1b3d0b0b175bfdbc5cb277554 266 Gene3D G3DSA:3.40.50.2300 3 116 5.8E-40 T 12-10-2018 UA74_15665 153a878e323010d955987a7553e59517 346 SUPERFAMILY SSF56349 46 329 2.53E-33 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_15665 153a878e323010d955987a7553e59517 346 Pfam PF00589 Phage integrase family 164 312 1.7E-11 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_15665 153a878e323010d955987a7553e59517 346 Gene3D G3DSA:1.10.443.10 161 340 1.1E-18 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_15665 153a878e323010d955987a7553e59517 346 Gene3D G3DSA:1.10.150.130 37 151 3.3E-9 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_02315 4bfeff7e5cd27ec9b183249fcca00863 267 SUPERFAMILY SSF46785 36 108 2.45E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_02315 4bfeff7e5cd27ec9b183249fcca00863 267 Gene3D G3DSA:1.10.10.10 34 105 2.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02315 4bfeff7e5cd27ec9b183249fcca00863 267 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 30 238 34.817 T 12-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 UA74_02315 4bfeff7e5cd27ec9b183249fcca00863 267 Pfam PF02629 CoA binding domain 111 208 4.2E-19 T 12-10-2018 IPR003781 CoA-binding GO:0048037 UA74_02315 4bfeff7e5cd27ec9b183249fcca00863 267 SUPERFAMILY SSF51735 113 233 2.03E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_02315 4bfeff7e5cd27ec9b183249fcca00863 267 SMART SM00881 108 209 6.0E-17 T 12-10-2018 IPR003781 CoA-binding GO:0048037 UA74_02315 4bfeff7e5cd27ec9b183249fcca00863 267 Gene3D G3DSA:3.40.50.720 106 237 4.7E-43 T 12-10-2018 UA74_02315 4bfeff7e5cd27ec9b183249fcca00863 267 Pfam PF06971 Putative DNA-binding protein N-terminus 35 82 5.5E-18 T 12-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 UA74_20860 2c9991fa94fc6eebe915539bb0dd1833 274 Gene3D G3DSA:3.40.50.150 36 233 3.2E-25 T 12-10-2018 UA74_20860 2c9991fa94fc6eebe915539bb0dd1833 274 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 62 136 8.2E-8 T 12-10-2018 UA74_20860 2c9991fa94fc6eebe915539bb0dd1833 274 SUPERFAMILY SSF53335 32 206 5.14E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_16000 074ad5b63c8d07587baf46c8bb4e82b2 315 SUPERFAMILY SSF56436 111 305 9.18E-50 T 12-10-2018 IPR016187 C-type lectin fold UA74_16000 074ad5b63c8d07587baf46c8bb4e82b2 315 SMART SM00530 13 66 0.0053 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_16000 074ad5b63c8d07587baf46c8bb4e82b2 315 SUPERFAMILY SSF47413 7 47 2.03E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_16000 074ad5b63c8d07587baf46c8bb4e82b2 315 Pfam PF03781 Sulfatase-modifying factor enzyme 1 123 303 3.7E-35 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 UA74_16000 074ad5b63c8d07587baf46c8bb4e82b2 315 Gene3D G3DSA:3.90.1580.10 109 305 2.3E-45 T 12-10-2018 UA74_16000 074ad5b63c8d07587baf46c8bb4e82b2 315 Gene3D G3DSA:1.10.260.40 13 76 8.2E-9 T 12-10-2018 UA74_16000 074ad5b63c8d07587baf46c8bb4e82b2 315 Pfam PF13560 Helix-turn-helix domain 11 65 8.0E-7 T 12-10-2018 UA74_23350 0869627ea9c7e71b07294dbda485b113 481 Gene3D G3DSA:3.30.43.10 27 103 2.0E-16 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 UA74_23350 0869627ea9c7e71b07294dbda485b113 481 Pfam PF08031 Berberine and berberine like 432 466 5.9E-7 T 12-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 UA74_23350 0869627ea9c7e71b07294dbda485b113 481 SUPERFAMILY SSF56176 15 217 3.92E-46 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_23350 0869627ea9c7e71b07294dbda485b113 481 Gene3D G3DSA:3.30.465.10 117 454 3.2E-91 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_23350 0869627ea9c7e71b07294dbda485b113 481 Gene3D G3DSA:3.40.462.20 217 425 3.2E-91 T 12-10-2018 UA74_23350 0869627ea9c7e71b07294dbda485b113 481 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 52 85 - T 12-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 UA74_23350 0869627ea9c7e71b07294dbda485b113 481 Pfam PF01565 FAD binding domain 52 185 2.1E-25 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_13200 2466d29a9c88dd9e9d92380783f4f375 562 Pfam PF00664 ABC transporter transmembrane region 29 282 7.9E-10 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_13200 2466d29a9c88dd9e9d92380783f4f375 562 Pfam PF00005 ABC transporter 345 491 3.1E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13200 2466d29a9c88dd9e9d92380783f4f375 562 Gene3D G3DSA:1.20.1560.10 2 313 8.7E-34 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13200 2466d29a9c88dd9e9d92380783f4f375 562 SMART SM00382 354 537 7.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13200 2466d29a9c88dd9e9d92380783f4f375 562 SUPERFAMILY SSF90123 8 321 1.83E-37 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13200 2466d29a9c88dd9e9d92380783f4f375 562 SUPERFAMILY SSF52540 324 551 8.63E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13200 2466d29a9c88dd9e9d92380783f4f375 562 Gene3D G3DSA:3.40.50.300 324 560 3.2E-53 T 12-10-2018 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 366 572 4.4E-36 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 Gene3D G3DSA:3.30.54.20 136 215 1.8E-56 T 12-10-2018 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 SMART SM00863 191 247 4.4E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 SUPERFAMILY SSF55186 70 268 8.11E-49 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 Gene3D G3DSA:3.30.980.10 75 250 1.8E-56 T 12-10-2018 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 200 247 1.3E-12 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 SUPERFAMILY SSF52954 572 679 1.51E-28 T 12-10-2018 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 Pfam PF03129 Anticodon binding domain 584 672 2.0E-16 T 12-10-2018 IPR004154 Anticodon-binding UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 72 677 33.318 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 78 671 2.1E-190 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 Gene3D G3DSA:3.40.50.800 576 683 7.3E-24 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 SUPERFAMILY SSF55681 271 568 1.19E-93 T 12-10-2018 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 Gene3D G3DSA:3.30.930.10 254 575 1.2E-116 T 12-10-2018 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 PRINTS PR01047 Threonyl-tRNA synthetase signature 371 399 2.2E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 PRINTS PR01047 Threonyl-tRNA synthetase signature 550 563 2.2E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 535 2.2E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 PRINTS PR01047 Threonyl-tRNA synthetase signature 404 427 2.2E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_10755 a404186ad4863c1b301bc716f0639d6b 694 PRINTS PR01047 Threonyl-tRNA synthetase signature 577 589 2.2E-51 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UA74_02405 7e26fa06bd4f3e82c110ca0b4db45c2c 324 Pfam PF01578 Cytochrome C assembly protein 110 318 5.8E-44 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 UA74_02405 7e26fa06bd4f3e82c110ca0b4db45c2c 324 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 87 321 3.0E-72 T 12-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 UA74_08395 fb56062fb9b26bc195e4043ca9dc1f4b 596 Pfam PF04851 Type III restriction enzyme, res subunit 27 180 1.3E-13 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_08395 fb56062fb9b26bc195e4043ca9dc1f4b 596 Gene3D G3DSA:3.40.50.300 208 395 1.3E-10 T 12-10-2018 UA74_08395 fb56062fb9b26bc195e4043ca9dc1f4b 596 SUPERFAMILY SSF52540 142 387 5.05E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08395 fb56062fb9b26bc195e4043ca9dc1f4b 596 SUPERFAMILY SSF52540 27 184 2.87E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08395 fb56062fb9b26bc195e4043ca9dc1f4b 596 SMART SM00487 24 207 4.8E-12 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_08395 fb56062fb9b26bc195e4043ca9dc1f4b 596 Gene3D G3DSA:3.40.50.300 20 189 6.0E-22 T 12-10-2018 UA74_03320 6ea28050172182d4a03e478e3bc4cff0 224 Gene3D G3DSA:1.20.120.520 6 161 4.9E-26 T 12-10-2018 UA74_03320 6ea28050172182d4a03e478e3bc4cff0 224 Pfam PF01814 Hemerythrin HHE cation binding domain 13 144 1.4E-13 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 UA74_03120 2b40ccf80060da414bfd87960cf34569 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 2.9E-38 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 UA74_03120 2b40ccf80060da414bfd87960cf34569 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.567 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 UA74_03120 2b40ccf80060da414bfd87960cf34569 73 SUPERFAMILY SSF50249 4 72 3.94E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_03120 2b40ccf80060da414bfd87960cf34569 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 2.3E-29 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 UA74_03120 2b40ccf80060da414bfd87960cf34569 73 Gene3D G3DSA:2.40.50.140 1 73 1.5E-38 T 12-10-2018 UA74_27870 df5299008b14029bd0cde913b628430d 363 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 2 361 6.3E-165 T 12-10-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 UA74_27870 df5299008b14029bd0cde913b628430d 363 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 5 292 1.5E-35 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 UA74_27870 df5299008b14029bd0cde913b628430d 363 SUPERFAMILY SSF51412 2 362 5.49E-62 T 12-10-2018 UA74_27870 df5299008b14029bd0cde913b628430d 363 SMART SM01240 2 363 1.3E-16 T 12-10-2018 UA74_27870 df5299008b14029bd0cde913b628430d 363 Gene3D G3DSA:3.20.20.70 3 362 7.5E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_18760 ced4168baf9949ca3966dd8eaeea5b0e 262 SMART SM00346 13 102 5.6E-18 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_18760 ced4168baf9949ca3966dd8eaeea5b0e 262 Gene3D G3DSA:3.30.450.40 88 256 3.1E-49 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_18760 ced4168baf9949ca3966dd8eaeea5b0e 262 Pfam PF09339 IclR helix-turn-helix domain 15 65 2.1E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_18760 ced4168baf9949ca3966dd8eaeea5b0e 262 Gene3D G3DSA:1.10.10.10 9 80 1.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18760 ced4168baf9949ca3966dd8eaeea5b0e 262 SUPERFAMILY SSF55781 78 253 1.57E-45 T 12-10-2018 UA74_18760 ced4168baf9949ca3966dd8eaeea5b0e 262 SUPERFAMILY SSF46785 13 85 6.12E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18760 ced4168baf9949ca3966dd8eaeea5b0e 262 Pfam PF01614 Bacterial transcriptional regulator 130 251 2.2E-25 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_09190 26e15011ffef84277ded12f1c12aba90 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 1.6E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 1.6E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 1.6E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 1.6E-15 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 Gene3D G3DSA:3.30.930.10 13 478 8.3E-208 T 12-10-2018 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 Pfam PF04073 Aminoacyl-tRNA editing domain 259 387 1.3E-20 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 471 4.8E-37 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 Gene3D G3DSA:3.40.50.800 5 564 8.3E-208 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily UA74_09190 26e15011ffef84277ded12f1c12aba90 582 Pfam PF03129 Anticodon binding domain 493 578 4.5E-18 T 12-10-2018 IPR004154 Anticodon-binding UA74_09190 26e15011ffef84277ded12f1c12aba90 582 SUPERFAMILY SSF52954 477 581 6.34E-28 T 12-10-2018 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 576 3.2E-165 T 12-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 Gene3D G3DSA:3.90.960.10 242 402 8.3E-208 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 SUPERFAMILY SSF55826 255 385 1.06E-9 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 581 36.398 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 UA74_09190 26e15011ffef84277ded12f1c12aba90 582 SUPERFAMILY SSF55681 12 490 7.65E-87 T 12-10-2018 UA74_10575 db9235e29ca378997ab8e601a1f48fe1 323 SUPERFAMILY SSF53807 39 315 5.49E-43 T 12-10-2018 UA74_10575 db9235e29ca378997ab8e601a1f48fe1 323 Pfam PF01497 Periplasmic binding protein 58 299 3.5E-15 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_10575 db9235e29ca378997ab8e601a1f48fe1 323 Gene3D G3DSA:3.40.50.1980 146 323 3.1E-34 T 12-10-2018 UA74_10575 db9235e29ca378997ab8e601a1f48fe1 323 Gene3D G3DSA:3.40.50.1980 34 143 2.1E-17 T 12-10-2018 UA74_28485 4bd1444582d5835632d16736ddde1a7b 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 227 2.8E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_28485 4bd1444582d5835632d16736ddde1a7b 255 Gene3D G3DSA:1.10.3720.10 47 244 4.5E-18 T 12-10-2018 IPR035906 MetI-like superfamily UA74_28485 4bd1444582d5835632d16736ddde1a7b 255 SUPERFAMILY SSF161098 49 238 9.81E-24 T 12-10-2018 IPR035906 MetI-like superfamily UA74_03665 db2d00150ff7c58a0a3789578ec70bd6 188 Pfam PF14124 Domain of unknown function (DUF4291) 5 182 2.2E-69 T 12-10-2018 IPR025633 Protein of unknown function DUF4291 UA74_12545 68b081a2175ecf20456e9e1354fb9035 153 Pfam PF01592 NifU-like N terminal domain 6 131 5.7E-27 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 UA74_12545 68b081a2175ecf20456e9e1354fb9035 153 SUPERFAMILY SSF82649 2 145 3.66E-42 T 12-10-2018 UA74_12545 68b081a2175ecf20456e9e1354fb9035 153 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 143 3.6E-46 T 12-10-2018 UA74_12545 68b081a2175ecf20456e9e1354fb9035 153 Gene3D G3DSA:3.90.1010.10 1 148 9.3E-45 T 12-10-2018 UA74_18915 4bdf3b7de7cd15c134e2a6b1b0527a07 881 Gene3D G3DSA:2.130.10.10 41 758 0.0 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_18915 4bdf3b7de7cd15c134e2a6b1b0527a07 881 SUPERFAMILY SSF49384 777 878 1.26E-31 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UA74_18915 4bdf3b7de7cd15c134e2a6b1b0527a07 881 SMART SM00637 783 878 1.6E-38 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_18915 4bdf3b7de7cd15c134e2a6b1b0527a07 881 Gene3D G3DSA:2.130.10.10 51 465 0.0 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_18915 4bdf3b7de7cd15c134e2a6b1b0527a07 881 SUPERFAMILY SSF110296 456 761 2.35E-40 T 12-10-2018 UA74_18915 4bdf3b7de7cd15c134e2a6b1b0527a07 881 Pfam PF00553 Cellulose binding domain 783 880 5.7E-28 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_18915 4bdf3b7de7cd15c134e2a6b1b0527a07 881 SUPERFAMILY SSF110296 41 446 2.35E-81 T 12-10-2018 UA74_18915 4bdf3b7de7cd15c134e2a6b1b0527a07 881 Gene3D G3DSA:2.60.40.290 779 881 1.0E-32 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 6.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 250 2.8E-61 T 12-10-2018 UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 SUPERFAMILY SSF51735 6 249 1.83E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.9E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11025 8b9bfd95a73769bdff5d33468cf670e6 250 Gene3D G3DSA:3.40.50.720 3 250 1.1E-75 T 12-10-2018 UA74_08275 10d70e0cc11505bcb44ef83c09817426 249 Gene3D G3DSA:3.10.560.10 96 161 2.1E-9 T 12-10-2018 UA74_08275 10d70e0cc11505bcb44ef83c09817426 249 Pfam PF10531 SLBB domain 102 156 1.2E-11 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_08275 10d70e0cc11505bcb44ef83c09817426 249 SMART SM00278 227 246 3.8 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_08275 10d70e0cc11505bcb44ef83c09817426 249 SMART SM00278 197 216 0.016 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UA74_08275 10d70e0cc11505bcb44ef83c09817426 249 Gene3D G3DSA:1.10.150.320 175 248 5.5E-25 T 12-10-2018 UA74_08275 10d70e0cc11505bcb44ef83c09817426 249 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 187 248 1.4E-16 T 12-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain UA74_08275 10d70e0cc11505bcb44ef83c09817426 249 Pfam PF12836 Helix-hairpin-helix motif 187 248 7.9E-23 T 12-10-2018 UA74_08275 10d70e0cc11505bcb44ef83c09817426 249 SUPERFAMILY SSF47781 182 248 7.56E-28 T 12-10-2018 IPR010994 RuvA domain 2-like UA74_14770 026ec8437e00545c796eb40a58e4f2f4 366 SUPERFAMILY SSF51395 9 355 5.98E-84 T 12-10-2018 UA74_14770 026ec8437e00545c796eb40a58e4f2f4 366 PIRSF PIRSF000138 1 361 5.3E-120 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 UA74_14770 026ec8437e00545c796eb40a58e4f2f4 366 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 257 263 - T 12-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 UA74_14770 026ec8437e00545c796eb40a58e4f2f4 366 Pfam PF01070 FMN-dependent dehydrogenase 18 354 3.5E-119 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 UA74_14770 026ec8437e00545c796eb40a58e4f2f4 366 Gene3D G3DSA:3.20.20.70 8 362 3.8E-125 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 6.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.2E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 5.4E-65 T 12-10-2018 UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 SUPERFAMILY SSF51735 5 246 6.44E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 221 5.6E-7 T 12-10-2018 UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 Gene3D G3DSA:3.40.50.720 4 248 8.6E-83 T 12-10-2018 UA74_05710 226a6903a85f0de1720ea6742d0139a3 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_10020 4e99855cb81af50ba7f9dbcda5105ac9 198 SUPERFAMILY SSF46785 67 197 2.16E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_10020 4e99855cb81af50ba7f9dbcda5105ac9 198 Gene3D G3DSA:1.10.10.10 62 198 3.2E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_25280 ee95451134bd1ac51df74ed6d933920c 300 Pfam PF02104 SURF1 family 28 231 2.4E-26 T 12-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_10785 374f8cfc11abf8e9ad396d283fb5ed41 213 Gene3D G3DSA:2.70.50.50 32 213 2.5E-63 T 12-10-2018 UA74_10785 374f8cfc11abf8e9ad396d283fb5ed41 213 SUPERFAMILY SSF81296 32 213 4.06E-48 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_10785 374f8cfc11abf8e9ad396d283fb5ed41 213 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 209 1.6E-43 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal UA74_00855 040efbeea172a5890695f6d9ac470a17 175 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 23 166 6.6E-50 T 12-10-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative UA74_29765 fa2b0db11730058f445269d37fac8a7d 100 SUPERFAMILY SSF54909 3 93 9.58E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_29765 fa2b0db11730058f445269d37fac8a7d 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 2.4E-11 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_29765 fa2b0db11730058f445269d37fac8a7d 100 Gene3D G3DSA:3.30.70.100 1 94 8.9E-18 T 12-10-2018 UA74_10335 6318089d6b01c7d43da1efa0dec3a3a1 476 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 16 338 2.4E-88 T 12-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme UA74_10335 6318089d6b01c7d43da1efa0dec3a3a1 476 SUPERFAMILY SSF102114 86 319 1.7E-27 T 12-10-2018 UA74_10335 6318089d6b01c7d43da1efa0dec3a3a1 476 Pfam PF04055 Radical SAM superfamily 88 241 1.5E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_10335 6318089d6b01c7d43da1efa0dec3a3a1 476 Gene3D G3DSA:3.20.20.70 69 292 1.2E-29 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_26665 8f9eb6f8e1175dbfa95f6cc46a6f6175 444 SUPERFAMILY SSF53448 9 358 6.38E-40 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_26665 8f9eb6f8e1175dbfa95f6cc46a6f6175 444 Gene3D G3DSA:3.90.550.10 256 344 9.4E-10 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_26665 8f9eb6f8e1175dbfa95f6cc46a6f6175 444 Pfam PF00535 Glycosyl transferase family 2 10 134 7.2E-19 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_26665 8f9eb6f8e1175dbfa95f6cc46a6f6175 444 Gene3D G3DSA:3.90.550.10 2 146 8.2E-23 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF00270 DEAD/DEAH box helicase 30 187 3.8E-18 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 SMART SM00341 541 612 4.0E-8 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 SUPERFAMILY SSF47819 541 612 8.72E-21 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 16 468 7.6E-148 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 SUPERFAMILY SSF52540 209 461 1.71E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 Gene3D G3DSA:1.10.10.10 343 528 2.0E-47 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 SMART SM00956 413 519 1.6E-43 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 16 611 2.0E-229 T 12-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 SMART SM00487 23 217 8.1E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF16124 RecQ zinc-binding 345 406 1.5E-17 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 Gene3D G3DSA:1.10.150.80 545 613 5.7E-23 T 12-10-2018 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF00271 Helicase conserved C-terminal domain 226 332 9.4E-16 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 SMART SM00490 252 333 1.2E-23 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 SUPERFAMILY SSF52540 13 198 5.33E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 Gene3D G3DSA:3.40.50.300 210 342 1.4E-38 T 12-10-2018 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 Gene3D G3DSA:3.40.50.300 6 209 1.1E-77 T 12-10-2018 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF00570 HRDC domain 547 610 2.3E-22 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_10535 9df65b058af21be22f7cdfc4b2d49acf 613 Pfam PF09382 RQC domain 408 522 1.5E-34 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 UA74_11930 6fe94298e95f4385a5085bbe296e1415 373 Gene3D G3DSA:3.40.50.970 6 366 8.9E-120 T 12-10-2018 UA74_11930 6fe94298e95f4385a5085bbe296e1415 373 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 45 357 5.7E-129 T 12-10-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 UA74_11930 6fe94298e95f4385a5085bbe296e1415 373 SUPERFAMILY SSF52518 41 359 2.86E-98 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_11930 6fe94298e95f4385a5085bbe296e1415 373 Pfam PF00676 Dehydrogenase E1 component 52 348 3.1E-81 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 SUPERFAMILY SSF52540 235 546 2.14E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 Gene3D G3DSA:2.40.50.140 156 235 1.0E-24 T 12-10-2018 UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 Gene3D G3DSA:1.10.8.60 428 473 1.5E-61 T 12-10-2018 UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 Gene3D G3DSA:2.40.50.140 96 155 3.0E-28 T 12-10-2018 UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 Gene3D G3DSA:1.20.5.170 54 95 7.8E-18 T 12-10-2018 UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 ProSitePatterns PS00674 AAA-protein family signature. 397 415 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 Pfam PF16450 Proteasomal ATPase OB/ID domain 99 234 1.3E-52 T 12-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 55 575 1.1E-256 T 12-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 SMART SM00382 273 429 9.8E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 57 576 50.861 T 12-10-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 Gene3D G3DSA:3.40.50.300 236 427 1.5E-61 T 12-10-2018 UA74_12855 6f9807d63cde95d3a16a9571b193d1b3 597 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 277 427 3.3E-48 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_04950 074a3449eb04746c97f7b8b423d75025 388 SUPERFAMILY SSF51905 2 379 2.46E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_04950 074a3449eb04746c97f7b8b423d75025 388 Gene3D G3DSA:3.90.660.50 81 170 2.5E-17 T 12-10-2018 UA74_04950 074a3449eb04746c97f7b8b423d75025 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 349 356 1.3E-5 T 12-10-2018 UA74_04950 074a3449eb04746c97f7b8b423d75025 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.3E-5 T 12-10-2018 UA74_04950 074a3449eb04746c97f7b8b423d75025 388 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 63 2.0E-8 T 12-10-2018 UA74_04950 074a3449eb04746c97f7b8b423d75025 388 Gene3D G3DSA:3.50.50.60 7 209 2.5E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_04115 ea3dae74af763d5da821bfc71d579d66 383 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 67 356 1.5E-38 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UA74_04115 ea3dae74af763d5da821bfc71d579d66 383 SUPERFAMILY SSF51695 62 362 1.91E-59 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_04115 ea3dae74af763d5da821bfc71d579d66 383 Gene3D G3DSA:3.20.20.190 50 370 1.7E-96 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_18295 8e591cccd644241e5cac89d6004f0719 330 SUPERFAMILY SSF52317 5 198 4.58E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_18295 8e591cccd644241e5cac89d6004f0719 330 Gene3D G3DSA:3.40.50.880 1 216 3.0E-62 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_18295 8e591cccd644241e5cac89d6004f0719 330 SMART SM00342 233 316 2.3E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_18295 8e591cccd644241e5cac89d6004f0719 330 Pfam PF12833 Helix-turn-helix domain 239 317 2.0E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_18295 8e591cccd644241e5cac89d6004f0719 330 Pfam PF01965 DJ-1/PfpI family 6 177 5.3E-25 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UA74_18295 8e591cccd644241e5cac89d6004f0719 330 Gene3D G3DSA:1.10.10.60 217 329 1.0E-25 T 12-10-2018 UA74_18295 8e591cccd644241e5cac89d6004f0719 330 SUPERFAMILY SSF46689 218 267 4.93E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_18295 8e591cccd644241e5cac89d6004f0719 330 SUPERFAMILY SSF46689 269 320 1.34E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_17055 f8624abd27e5c0e0cd0ac5194d793ad8 476 Gene3D G3DSA:2.115.10.20 160 476 2.6E-144 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_17055 f8624abd27e5c0e0cd0ac5194d793ad8 476 SUPERFAMILY SSF49384 44 149 1.05E-27 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UA74_17055 f8624abd27e5c0e0cd0ac5194d793ad8 476 Pfam PF00553 Cellulose binding domain 47 147 4.5E-28 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_17055 f8624abd27e5c0e0cd0ac5194d793ad8 476 Gene3D G3DSA:2.60.40.290 40 150 7.0E-32 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 UA74_17055 f8624abd27e5c0e0cd0ac5194d793ad8 476 Pfam PF03664 Glycosyl hydrolase family 62 159 443 2.5E-59 T 12-10-2018 IPR005193 Glycoside hydrolase, family 62, arabinosidase GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 UA74_17055 f8624abd27e5c0e0cd0ac5194d793ad8 476 SUPERFAMILY SSF75005 186 467 9.42E-22 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_17055 f8624abd27e5c0e0cd0ac5194d793ad8 476 SMART SM00637 47 147 5.5E-40 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_20020 b176a7daf4d633a8a01e411045b88088 334 Gene3D G3DSA:3.40.50.1820 6 320 2.2E-75 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20020 b176a7daf4d633a8a01e411045b88088 334 SUPERFAMILY SSF53474 27 324 4.12E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20020 b176a7daf4d633a8a01e411045b88088 334 Pfam PF05448 Acetyl xylan esterase (AXE1) 28 319 1.1E-63 T 12-10-2018 IPR008391 Acetyl xylan esterase UA74_03185 855adce3861148b194260bd74c7fca94 143 Pfam PF00583 Acetyltransferase (GNAT) family 38 121 2.5E-8 T 12-10-2018 IPR000182 GNAT domain UA74_03185 855adce3861148b194260bd74c7fca94 143 SUPERFAMILY SSF55729 4 122 9.92E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_03185 855adce3861148b194260bd74c7fca94 143 Gene3D G3DSA:3.40.630.30 2 137 3.9E-23 T 12-10-2018 UA74_21110 17e87e68295d31509594a8ea02cab536 253 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 7 253 1.6E-104 T 12-10-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.127|MetaCyc: PWY-6507|MetaCyc: PWY-7562 UA74_21110 17e87e68295d31509594a8ea02cab536 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 179 0.003 T 12-10-2018 UA74_21110 17e87e68295d31509594a8ea02cab536 253 SUPERFAMILY SSF51735 7 252 6.0E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_21110 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21110 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21110 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21110 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.6E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21110 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.6E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21110 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 5.6E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21110 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 5.6E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21110 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.6E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21110 17e87e68295d31509594a8ea02cab536 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.6E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21110 17e87e68295d31509594a8ea02cab536 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_21110 17e87e68295d31509594a8ea02cab536 253 Gene3D G3DSA:3.40.50.720 3 253 3.8E-78 T 12-10-2018 UA74_21110 17e87e68295d31509594a8ea02cab536 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 250 2.3E-58 T 12-10-2018 UA74_20505 e510cb689c4003250db628d6db388883 343 PIRSF PIRSF006470 14 340 5.0E-77 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 UA74_20505 e510cb689c4003250db628d6db388883 343 Gene3D G3DSA:3.40.190.170 42 338 1.9E-86 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily UA74_20505 e510cb689c4003250db628d6db388883 343 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 325 2.4E-78 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 UA74_20505 e510cb689c4003250db628d6db388883 343 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 50 299 6.3E-64 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 Pfam PF01595 Domain of unknown function DUF21 6 181 2.8E-35 T 12-10-2018 IPR002550 CNNM, transmembrane domain UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 SMART SM00116 206 255 4.7E-4 T 12-10-2018 IPR000644 CBS domain UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 SMART SM00116 276 324 15.0 T 12-10-2018 IPR000644 CBS domain UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 SUPERFAMILY SSF54631 184 327 2.65E-32 T 12-10-2018 UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 SUPERFAMILY SSF56176 335 408 1.88E-12 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 Gene3D G3DSA:3.10.580.10 177 330 1.6E-51 T 12-10-2018 UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 Pfam PF00571 CBS domain 273 324 2.0E-4 T 12-10-2018 IPR000644 CBS domain UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 Pfam PF00571 CBS domain 197 252 8.1E-8 T 12-10-2018 IPR000644 CBS domain UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 SMART SM01091 340 422 7.1E-19 T 12-10-2018 IPR005170 Transporter-associated domain UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 Pfam PF03471 Transporter associated domain 341 403 8.7E-11 T 12-10-2018 IPR005170 Transporter-associated domain UA74_24485 74e4fa428b1c94f8f7a7ceca0deb0117 447 Gene3D G3DSA:3.30.465.10 331 422 1.2E-17 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_05090 54971d6258fb2358de9386003d6ab1a4 217 PIRSF PIRSF000709 1 171 5.7E-6 T 12-10-2018 UA74_05090 54971d6258fb2358de9386003d6ab1a4 217 SUPERFAMILY SSF53254 1 215 3.8E-41 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_05090 54971d6258fb2358de9386003d6ab1a4 217 SMART SM00855 5 161 6.2E-15 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_05090 54971d6258fb2358de9386003d6ab1a4 217 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 196 2.4E-39 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_05090 54971d6258fb2358de9386003d6ab1a4 217 Gene3D G3DSA:3.40.50.1240 1 217 1.3E-40 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_05090 54971d6258fb2358de9386003d6ab1a4 217 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 UA74_11365 cc2076c1ceff99834245571ba177c576 202 SUPERFAMILY SSF46609 2 84 2.09E-32 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 83 9.3E-32 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 66 79 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 119 127 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 PRINTS PR01703 Manganese superoxide dismutase signature 157 169 1.3E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 SUPERFAMILY SSF54719 83 196 1.1E-42 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 PIRSF PIRSF000349 1 201 9.8E-77 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 Gene3D G3DSA:1.10.287.990 20 83 3.2E-26 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 Gene3D G3DSA:2.40.500.20 84 201 1.2E-44 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 159 166 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_11365 cc2076c1ceff99834245571ba177c576 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 90 192 3.5E-34 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_00105 7bf178fb25ebebf1717848195c1280a0 462 Pfam PF04203 Sortase family 271 442 4.5E-27 T 12-10-2018 IPR005754 Sortase family UA74_00105 7bf178fb25ebebf1717848195c1280a0 462 SUPERFAMILY SSF63817 226 444 3.3E-27 T 12-10-2018 IPR023365 Sortase domain superfamily UA74_20495 e806315451b38159f69b7abf5448f178 141 Pfam PF01042 Endoribonuclease L-PSP 26 134 3.1E-21 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UA74_20495 e806315451b38159f69b7abf5448f178 141 Gene3D G3DSA:3.30.1330.40 11 140 3.5E-33 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_20495 e806315451b38159f69b7abf5448f178 141 SUPERFAMILY SSF55298 25 136 1.37E-30 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_10825 f07b8519d7c5be3568f99ca3ffb1744e 206 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 7 202 37.632 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_10825 f07b8519d7c5be3568f99ca3ffb1744e 206 Pfam PF01174 SNO glutamine amidotransferase family 9 203 6.8E-54 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_10825 f07b8519d7c5be3568f99ca3ffb1744e 206 PIRSF PIRSF005639 1 206 4.3E-68 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_10825 f07b8519d7c5be3568f99ca3ffb1744e 206 SUPERFAMILY SSF52317 6 203 7.99E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_10825 f07b8519d7c5be3568f99ca3ffb1744e 206 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 7 200 1.5E-68 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_10825 f07b8519d7c5be3568f99ca3ffb1744e 206 Gene3D G3DSA:3.40.50.880 4 206 3.0E-70 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_10825 f07b8519d7c5be3568f99ca3ffb1744e 206 ProSitePatterns PS01236 PdxT/SNO family family signature. 44 54 - T 12-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UA74_00945 7d20317d5d89e7dc8de54c1d14a651c1 282 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_00945 7d20317d5d89e7dc8de54c1d14a651c1 282 SMART SM00382 35 235 1.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_00945 7d20317d5d89e7dc8de54c1d14a651c1 282 Gene3D G3DSA:3.40.50.300 4 274 9.8E-87 T 12-10-2018 UA74_00945 7d20317d5d89e7dc8de54c1d14a651c1 282 SUPERFAMILY SSF52540 6 248 1.02E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00945 7d20317d5d89e7dc8de54c1d14a651c1 282 Pfam PF00005 ABC transporter 27 178 2.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_17360 ef1df61255e54acbe90a923efe4f6e50 223 SUPERFAMILY SSF46689 15 81 1.85E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_17360 ef1df61255e54acbe90a923efe4f6e50 223 SUPERFAMILY SSF48498 89 204 5.4E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_17360 ef1df61255e54acbe90a923efe4f6e50 223 Gene3D G3DSA:1.10.357.10 60 204 1.1E-34 T 12-10-2018 UA74_17360 ef1df61255e54acbe90a923efe4f6e50 223 Gene3D G3DSA:1.10.10.60 9 59 1.7E-19 T 12-10-2018 UA74_03570 a97748067b7fc1dfd53d8ae83fc5f524 321 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 9 298 31.638 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 UA74_03570 a97748067b7fc1dfd53d8ae83fc5f524 321 PIRSF PIRSF010376 8 307 9.7E-81 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 UA74_03570 a97748067b7fc1dfd53d8ae83fc5f524 321 Pfam PF00288 GHMP kinases N terminal domain 96 154 1.8E-8 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 UA74_03570 a97748067b7fc1dfd53d8ae83fc5f524 321 Gene3D G3DSA:3.30.70.890 170 312 4.9E-43 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UA74_03570 a97748067b7fc1dfd53d8ae83fc5f524 321 SUPERFAMILY SSF54211 8 167 4.25E-43 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_03570 a97748067b7fc1dfd53d8ae83fc5f524 321 Gene3D G3DSA:3.30.230.10 3 169 1.6E-62 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_03570 a97748067b7fc1dfd53d8ae83fc5f524 321 SUPERFAMILY SSF55060 173 293 2.09E-22 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UA74_03570 a97748067b7fc1dfd53d8ae83fc5f524 321 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 9 282 6.5E-52 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 UA74_03570 a97748067b7fc1dfd53d8ae83fc5f524 321 Pfam PF08544 GHMP kinases C terminal 213 285 1.4E-8 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain UA74_00775 1e330ed2d517f36f395ee3c67b5612a8 147 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_00775 1e330ed2d517f36f395ee3c67b5612a8 147 Gene3D G3DSA:3.90.79.10 3 137 7.0E-31 T 12-10-2018 UA74_00775 1e330ed2d517f36f395ee3c67b5612a8 147 SUPERFAMILY SSF55811 3 124 4.33E-31 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_00775 1e330ed2d517f36f395ee3c67b5612a8 147 Pfam PF00293 NUDIX domain 8 116 6.8E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_00775 1e330ed2d517f36f395ee3c67b5612a8 147 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.2E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_00775 1e330ed2d517f36f395ee3c67b5612a8 147 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.2E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 Gene3D G3DSA:3.40.50.200 208 505 7.9E-93 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 241 252 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 446 456 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 277 287 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 Pfam PF00082 Subtilase family 236 484 4.8E-60 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 Gene3D G3DSA:2.60.40.10 506 610 3.7E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 SUPERFAMILY SSF52743 218 503 5.11E-81 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 PRINTS PR00723 Subtilisin serine protease family (S8) signature 273 286 1.1E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 PRINTS PR00723 Subtilisin serine protease family (S8) signature 445 461 1.1E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_23930 2931b36441b0734ee4010f0a9117ee61 1124 PRINTS PR00723 Subtilisin serine protease family (S8) signature 236 255 1.1E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_25295 062df33521ca7ac4d7eaa5984bfc815b 729 Pfam PF09660 Protein of unknown function (DUF2397) 92 578 2.4E-113 T 12-10-2018 IPR013493 Conserved hypothetical protein CHP02677 UA74_02215 a6754fccb967b7802f8dfce209dc559b 408 SUPERFAMILY SSF52266 206 400 2.14E-34 T 12-10-2018 UA74_02215 a6754fccb967b7802f8dfce209dc559b 408 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 210 394 1.7E-18 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain UA74_02215 a6754fccb967b7802f8dfce209dc559b 408 Gene3D G3DSA:3.40.50.1110 197 405 2.3E-25 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_03390 3db180a6fd73b0ba0cae1ae36613cb37 211 SUPERFAMILY SSF51735 1 202 1.25E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_03390 3db180a6fd73b0ba0cae1ae36613cb37 211 Pfam PF13460 NAD(P)H-binding 7 199 4.3E-46 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_03390 3db180a6fd73b0ba0cae1ae36613cb37 211 Gene3D G3DSA:3.40.50.720 1 206 1.5E-47 T 12-10-2018 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 Pfam PF00067 Cytochrome P450 193 363 1.2E-19 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 SUPERFAMILY SSF48264 8 393 5.24E-96 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 335 344 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 Gene3D G3DSA:1.10.630.10 1 395 6.1E-134 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 150 165 9.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 342 353 9.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 87 98 9.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 186 208 9.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 284 311 9.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 266 277 9.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 133 149 9.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 333 342 9.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_19640 bb37e6acc8ab09d40347211992b9a492 395 PRINTS PR00359 B-class P450 signature 312 327 9.9E-54 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_07220 189eab36341ed3d93c9fe7de2d3cb0b8 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 61 95 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_07220 189eab36341ed3d93c9fe7de2d3cb0b8 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 9.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_07220 189eab36341ed3d93c9fe7de2d3cb0b8 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 9.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_07220 189eab36341ed3d93c9fe7de2d3cb0b8 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 9.8E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_07220 189eab36341ed3d93c9fe7de2d3cb0b8 144 Pfam PF01047 MarR family 34 86 3.4E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_07220 189eab36341ed3d93c9fe7de2d3cb0b8 144 SUPERFAMILY SSF46785 5 136 1.12E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_07220 189eab36341ed3d93c9fe7de2d3cb0b8 144 Gene3D G3DSA:1.10.10.10 1 141 3.4E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_07220 189eab36341ed3d93c9fe7de2d3cb0b8 144 SMART SM00347 20 121 1.4E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00930 4b232ac5a05dfb0844117e44f54eb232 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 304 6.2E-35 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_00930 4b232ac5a05dfb0844117e44f54eb232 311 SUPERFAMILY SSF161098 91 292 8.99E-14 T 12-10-2018 IPR035906 MetI-like superfamily UA74_00930 4b232ac5a05dfb0844117e44f54eb232 311 Gene3D G3DSA:1.10.3720.10 85 297 2.0E-16 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04255 dad0ae42f983b1ed04a1ba051e81e0a4 270 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_04255 dad0ae42f983b1ed04a1ba051e81e0a4 270 SMART SM00382 39 225 4.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_04255 dad0ae42f983b1ed04a1ba051e81e0a4 270 Gene3D G3DSA:3.40.50.300 14 267 1.4E-65 T 12-10-2018 UA74_04255 dad0ae42f983b1ed04a1ba051e81e0a4 270 SUPERFAMILY SSF52540 14 228 1.16E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04255 dad0ae42f983b1ed04a1ba051e81e0a4 270 Pfam PF00005 ABC transporter 30 176 2.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_12030 bc42cd3757fe90bcf77655fdf433cb10 510 SUPERFAMILY SSF53383 56 497 9.11E-105 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_12030 bc42cd3757fe90bcf77655fdf433cb10 510 Gene3D G3DSA:3.40.640.10 125 374 6.7E-112 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_12030 bc42cd3757fe90bcf77655fdf433cb10 510 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 112 430 7.8E-46 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 UA74_12030 bc42cd3757fe90bcf77655fdf433cb10 510 Gene3D G3DSA:3.90.1150.170 65 483 6.7E-112 T 12-10-2018 UA74_09585 08ed71f1fb10e809772aec5e92ae704c 813 Gene3D G3DSA:3.10.620.30 386 542 5.0E-20 T 12-10-2018 UA74_09585 08ed71f1fb10e809772aec5e92ae704c 813 Pfam PF01841 Transglutaminase-like superfamily 414 530 2.6E-23 T 12-10-2018 IPR002931 Transglutaminase-like UA74_09585 08ed71f1fb10e809772aec5e92ae704c 813 SUPERFAMILY SSF54001 400 534 2.52E-30 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UA74_09585 08ed71f1fb10e809772aec5e92ae704c 813 SMART SM00460 463 532 5.1E-17 T 12-10-2018 IPR002931 Transglutaminase-like UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 14 85 2.0E-32 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 SUPERFAMILY SSF50249 14 91 6.43E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 14 89 23.375 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 14 85 1.0E-28 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 Pfam PF00366 Ribosomal protein S17 19 86 1.1E-28 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 ProSitePatterns PS00056 Ribosomal protein S17 signature. 65 77 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 Gene3D G3DSA:2.40.50.140 13 92 4.6E-32 T 12-10-2018 UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 PRINTS PR00973 Ribosomal protein S17 family signature 33 56 3.6E-10 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 PRINTS PR00973 Ribosomal protein S17 family signature 75 82 3.6E-10 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02990 d543c74f8b44dfeccce5ab88e19b5de6 92 PRINTS PR00973 Ribosomal protein S17 family signature 65 75 3.6E-10 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_09940 36725959520739ed22b8f694a6b4c4c1 219 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 12 217 31.838 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UA74_09940 36725959520739ed22b8f694a6b4c4c1 219 SUPERFAMILY SSF52317 13 216 1.39E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_09940 36725959520739ed22b8f694a6b4c4c1 219 Gene3D G3DSA:3.40.50.880 9 218 1.2E-68 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_09940 36725959520739ed22b8f694a6b4c4c1 219 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 13 216 1.7E-65 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UA74_09940 36725959520739ed22b8f694a6b4c4c1 219 PIRSF PIRSF000495 11 219 6.7E-64 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UA74_09940 36725959520739ed22b8f694a6b4c4c1 219 Pfam PF00117 Glutamine amidotransferase class-I 15 212 3.6E-17 T 12-10-2018 IPR017926 Glutamine amidotransferase UA74_11730 e064ea56303a31dc35c12087a65046bf 154 SUPERFAMILY SSF52091 45 146 1.59E-17 T 12-10-2018 IPR036513 STAS domain superfamily UA74_11730 e064ea56303a31dc35c12087a65046bf 154 Pfam PF13466 STAS domain 52 132 3.2E-11 T 12-10-2018 IPR002645 STAS domain UA74_11730 e064ea56303a31dc35c12087a65046bf 154 Gene3D G3DSA:3.30.750.24 39 147 3.1E-23 T 12-10-2018 IPR036513 STAS domain superfamily UA74_11730 e064ea56303a31dc35c12087a65046bf 154 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 44 134 7.4E-17 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 UA74_21965 9077619a54c58e096b1df72367eb5f7f 228 SUPERFAMILY SSF55469 12 227 2.09E-35 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_21965 9077619a54c58e096b1df72367eb5f7f 228 Pfam PF00881 Nitroreductase family 16 203 8.6E-29 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_21965 9077619a54c58e096b1df72367eb5f7f 228 Gene3D G3DSA:3.40.109.10 4 224 1.7E-60 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_14675 97838930e4eca0b5f924f7163e4ad8a2 524 Pfam PF01565 FAD binding domain 63 196 2.6E-22 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_14675 97838930e4eca0b5f924f7163e4ad8a2 524 SUPERFAMILY SSF56176 27 225 1.17E-37 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_14675 97838930e4eca0b5f924f7163e4ad8a2 524 Gene3D G3DSA:3.40.462.20 228 473 2.2E-72 T 12-10-2018 UA74_14675 97838930e4eca0b5f924f7163e4ad8a2 524 Gene3D G3DSA:3.30.43.10 38 115 2.0E-14 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 UA74_14675 97838930e4eca0b5f924f7163e4ad8a2 524 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 63 96 - T 12-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 UA74_14675 97838930e4eca0b5f924f7163e4ad8a2 524 Gene3D G3DSA:3.30.465.10 128 502 2.2E-72 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_12540 15aec3e6c9f87a076ad6e99b994bb2be 436 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 232 251 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site UA74_12540 15aec3e6c9f87a076ad6e99b994bb2be 436 SUPERFAMILY SSF53383 9 419 4.76E-117 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_12540 15aec3e6c9f87a076ad6e99b994bb2be 436 Gene3D G3DSA:3.90.1150.10 13 414 7.7E-168 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_12540 15aec3e6c9f87a076ad6e99b994bb2be 436 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 12 423 8.1E-172 T 12-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 UA74_12540 15aec3e6c9f87a076ad6e99b994bb2be 436 Pfam PF00266 Aminotransferase class-V 31 411 6.5E-135 T 12-10-2018 IPR000192 Aminotransferase class V domain UA74_12540 15aec3e6c9f87a076ad6e99b994bb2be 436 Gene3D G3DSA:3.40.640.10 42 311 7.7E-168 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_18865 4a055725f8b4e69166e7d94faa3591cb 298 Gene3D G3DSA:1.10.3720.10 52 289 2.1E-60 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18865 4a055725f8b4e69166e7d94faa3591cb 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 283 2.4E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_18865 4a055725f8b4e69166e7d94faa3591cb 298 SUPERFAMILY SSF161098 54 280 5.23E-54 T 12-10-2018 IPR035906 MetI-like superfamily UA74_24600 253e51c1700fa576c59eb22cea03f611 175 SUPERFAMILY SSF55729 15 152 6.56E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_24600 253e51c1700fa576c59eb22cea03f611 175 Gene3D G3DSA:3.40.630.30 12 160 1.6E-14 T 12-10-2018 UA74_24600 253e51c1700fa576c59eb22cea03f611 175 Pfam PF00583 Acetyltransferase (GNAT) family 55 150 1.8E-9 T 12-10-2018 IPR000182 GNAT domain UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 116 125 8.9E-14 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 182 8.9E-14 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 8.9E-14 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 8.9E-14 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 8.9E-14 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 Pfam PF04324 BFD-like [2Fe-2S] binding domain 381 432 6.5E-8 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.4E-23 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 283 2.4E-23 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 2.4E-23 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 2.4E-23 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 2.4E-23 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 Gene3D G3DSA:3.50.50.60 125 275 1.0E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 Gene3D G3DSA:3.50.50.60 3 325 1.0E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 Gene3D G3DSA:1.10.10.1100 372 438 9.3E-14 T 12-10-2018 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 SUPERFAMILY SSF51905 1 338 1.21E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 PIRSF PIRSF037495 1 470 3.1E-120 T 12-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 UA74_16995 ea1f5ca55a9202b7c0d69dc2780c27eb 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 328 4.8E-28 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_24280 27e583d28924df7588198fcd81b8d838 426 Pfam PF07730 Histidine kinase 219 284 8.9E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_24280 27e583d28924df7588198fcd81b8d838 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 418 9.3E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_24280 27e583d28924df7588198fcd81b8d838 426 SMART SM00387 323 421 3.3E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_24280 27e583d28924df7588198fcd81b8d838 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 418 1.5E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_24280 27e583d28924df7588198fcd81b8d838 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 373 1.5E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_24280 27e583d28924df7588198fcd81b8d838 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 1.5E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_24280 27e583d28924df7588198fcd81b8d838 426 PIRSF PIRSF037434 6 423 2.6E-69 T 12-10-2018 IPR017205 Signal transduction histidine kinase, ChrS UA74_24280 27e583d28924df7588198fcd81b8d838 426 SUPERFAMILY SSF55874 290 418 1.44E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_24280 27e583d28924df7588198fcd81b8d838 426 Gene3D G3DSA:3.30.565.10 288 419 9.6E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_28265 aa4c49e91439b94ab01d595d299de3b1 378 PIRSF PIRSF000525 11 377 1.3E-76 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 UA74_28265 aa4c49e91439b94ab01d595d299de3b1 378 Pfam PF00266 Aminotransferase class-V 39 336 2.1E-12 T 12-10-2018 IPR000192 Aminotransferase class V domain UA74_28265 aa4c49e91439b94ab01d595d299de3b1 378 Gene3D G3DSA:3.40.640.10 33 271 5.7E-58 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_28265 aa4c49e91439b94ab01d595d299de3b1 378 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 11 377 23.895 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 UA74_28265 aa4c49e91439b94ab01d595d299de3b1 378 Gene3D G3DSA:3.90.1150.10 273 377 2.5E-40 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_28265 aa4c49e91439b94ab01d595d299de3b1 378 SUPERFAMILY SSF53383 23 376 2.96E-72 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_28265 aa4c49e91439b94ab01d595d299de3b1 378 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 18 377 3.4E-193 T 12-10-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 UA74_22520 63f4f26a86088fd83965ca005c15818f 286 SUPERFAMILY SSF55781 101 273 9.81E-45 T 12-10-2018 UA74_22520 63f4f26a86088fd83965ca005c15818f 286 SMART SM00346 32 123 3.0E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_22520 63f4f26a86088fd83965ca005c15818f 286 Gene3D G3DSA:3.30.450.40 103 279 5.8E-49 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_22520 63f4f26a86088fd83965ca005c15818f 286 SUPERFAMILY SSF46785 32 105 5.54E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22520 63f4f26a86088fd83965ca005c15818f 286 Pfam PF09339 IclR helix-turn-helix domain 34 85 1.1E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_22520 63f4f26a86088fd83965ca005c15818f 286 Gene3D G3DSA:1.10.10.10 29 100 1.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22520 63f4f26a86088fd83965ca005c15818f 286 Pfam PF01614 Bacterial transcriptional regulator 151 272 1.3E-29 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_23940 fc5e77f843009544e23bdd6d90224c4d 692 Gene3D G3DSA:2.130.10.10 328 406 3.8E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_23940 fc5e77f843009544e23bdd6d90224c4d 692 SUPERFAMILY SSF82171 32 415 4.71E-35 T 12-10-2018 UA74_23940 fc5e77f843009544e23bdd6d90224c4d 692 Gene3D G3DSA:2.120.10.30 147 308 4.7E-8 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_23940 fc5e77f843009544e23bdd6d90224c4d 692 Gene3D G3DSA:3.40.50.1820 425 686 1.7E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23940 fc5e77f843009544e23bdd6d90224c4d 692 SUPERFAMILY SSF53474 429 680 1.06E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23940 fc5e77f843009544e23bdd6d90224c4d 692 Pfam PF00326 Prolyl oligopeptidase family 474 680 1.1E-44 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_17380 745759acdc51e1dc602bc14a085b7b1c 344 Gene3D G3DSA:3.40.50.720 158 306 4.6E-88 T 12-10-2018 UA74_17380 745759acdc51e1dc602bc14a085b7b1c 344 SUPERFAMILY SSF50129 1 168 9.59E-44 T 12-10-2018 IPR011032 GroES-like superfamily UA74_17380 745759acdc51e1dc602bc14a085b7b1c 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 128 7.7E-23 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_17380 745759acdc51e1dc602bc14a085b7b1c 344 Pfam PF00107 Zinc-binding dehydrogenase 178 302 1.7E-18 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_17380 745759acdc51e1dc602bc14a085b7b1c 344 SUPERFAMILY SSF51735 148 310 1.41E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17380 745759acdc51e1dc602bc14a085b7b1c 344 Gene3D G3DSA:3.90.180.10 5 333 4.6E-88 T 12-10-2018 UA74_17445 be9832574563271981c7fef72021b3f3 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17445 be9832574563271981c7fef72021b3f3 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17445 be9832574563271981c7fef72021b3f3 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17445 be9832574563271981c7fef72021b3f3 253 Gene3D G3DSA:3.40.50.720 1 253 1.4E-74 T 12-10-2018 UA74_17445 be9832574563271981c7fef72021b3f3 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_17445 be9832574563271981c7fef72021b3f3 253 SUPERFAMILY SSF51735 5 252 1.31E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17445 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17445 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17445 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17445 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17445 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17445 be9832574563271981c7fef72021b3f3 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_17445 be9832574563271981c7fef72021b3f3 253 Pfam PF00106 short chain dehydrogenase 11 196 3.5E-57 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25725 bce50a6d6f2e181832adf4db49af0eb7 206 Gene3D G3DSA:1.10.357.10 3 182 7.3E-33 T 12-10-2018 UA74_25725 bce50a6d6f2e181832adf4db49af0eb7 206 SUPERFAMILY SSF46689 8 79 1.13E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_25725 bce50a6d6f2e181832adf4db49af0eb7 206 SUPERFAMILY SSF48498 80 167 1.75E-15 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_25725 bce50a6d6f2e181832adf4db49af0eb7 206 Pfam PF13305 WHG domain 85 165 2.3E-13 T 12-10-2018 IPR025996 WHG domain UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:3.10.600.10 459 1040 1.0E-228 T 12-10-2018 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF51569 517 829 1.59E-76 T 12-10-2018 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF89000 826 991 1.14E-38 T 12-10-2018 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 SMART SM00878 339 446 9.9E-55 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF52440 1 112 8.63E-41 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1081 1098 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF00682 HMGL-like 525 797 8.9E-31 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:2.40.50.100 1049 1125 1.0E-17 T 12-10-2018 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF00364 Biotin-requiring enzyme 1066 1124 4.6E-14 T 12-10-2018 IPR000089 Biotin/lipoyl attachment UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF02785 Biotin carboxylase C-terminal domain 339 447 1.6E-34 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:3.20.20.70 476 989 1.0E-228 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 6.6E-40 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1124 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 PIRSF PIRSF001594 1 1125 0.0 T 12-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF02436 Conserved carboxylase domain 821 1008 2.0E-52 T 12-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 322 2.2E-68 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 Gene3D G3DSA:3.30.470.130 1 454 1.2E-183 T 12-10-2018 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF51230 1048 1124 1.7E-16 T 12-10-2018 IPR011053 Single hybrid motif UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF51246 334 451 1.31E-37 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UA74_25635 4108725c1d44a9c1a8c90fbbdecde717 1125 SUPERFAMILY SSF56059 84 357 1.94E-67 T 12-10-2018 UA74_15015 1d42afd2110993bc5ac2102afb3c6b70 294 Gene3D G3DSA:3.40.50.720 5 269 2.2E-84 T 12-10-2018 UA74_15015 1d42afd2110993bc5ac2102afb3c6b70 294 Pfam PF13460 NAD(P)H-binding 8 187 3.0E-21 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_15015 1d42afd2110993bc5ac2102afb3c6b70 294 SUPERFAMILY SSF51735 4 247 2.78E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_15015 1d42afd2110993bc5ac2102afb3c6b70 294 Gene3D G3DSA:3.90.25.10 140 270 2.2E-84 T 12-10-2018 UA74_26485 d1470b424567894af2f5de15808f5e47 542 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 11 541 4.0E-238 T 12-10-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 UA74_26485 d1470b424567894af2f5de15808f5e47 542 Gene3D G3DSA:3.40.309.10 297 495 4.5E-196 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_26485 d1470b424567894af2f5de15808f5e47 542 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 292 299 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UA74_26485 d1470b424567894af2f5de15808f5e47 542 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 UA74_26485 d1470b424567894af2f5de15808f5e47 542 Gene3D G3DSA:3.40.605.10 14 527 4.5E-196 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_26485 d1470b424567894af2f5de15808f5e47 542 SUPERFAMILY SSF53720 9 527 8.51E-119 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_26485 d1470b424567894af2f5de15808f5e47 542 Pfam PF00171 Aldehyde dehydrogenase family 56 521 1.3E-99 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_24245 6e71b268c377a0e019e71298f7e1e696 180 Pfam PF03551 Transcriptional regulator PadR-like family 5 77 4.6E-10 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_24245 6e71b268c377a0e019e71298f7e1e696 180 Gene3D G3DSA:1.10.10.10 1 84 6.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24245 6e71b268c377a0e019e71298f7e1e696 180 SUPERFAMILY SSF46785 3 173 1.24E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 Gene3D G3DSA:3.40.250.10 142 275 4.2E-41 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 SUPERFAMILY SSF52821 5 139 6.16E-35 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 SMART SM00450 8 122 1.4E-21 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 SMART SM00450 144 271 4.5E-20 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 SUPERFAMILY SSF52821 149 274 5.24E-34 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 Pfam PF00581 Rhodanese-like domain 149 266 6.6E-17 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 Pfam PF00581 Rhodanese-like domain 9 118 3.4E-15 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 ProSitePatterns PS00380 Rhodanese signature 1. 34 45 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 UA74_29145 19f8463e1f1d3f6ca885829bc2685847 282 Gene3D G3DSA:3.40.250.10 1 141 3.6E-40 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_07890 828935e2ae53ad0ef50bcbf301b9a0d5 133 Gene3D G3DSA:1.10.490.10 10 133 3.1E-48 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UA74_07890 828935e2ae53ad0ef50bcbf301b9a0d5 133 Pfam PF01152 Bacterial-like globin 12 128 1.2E-35 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 UA74_07890 828935e2ae53ad0ef50bcbf301b9a0d5 133 SUPERFAMILY SSF46458 12 131 5.96E-36 T 12-10-2018 IPR009050 Globin-like superfamily UA74_07890 828935e2ae53ad0ef50bcbf301b9a0d5 133 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 59 83 - T 12-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 UA74_19120 180da2d9c8fc532ecb92c04850c6c713 234 Pfam PF06054 Competence protein CoiA-like family 8 113 1.1E-5 T 12-10-2018 IPR010330 Competence-induced protein CoiA-like UA74_12600 90aadfb082645f30cc665412f87b7fd7 241 SUPERFAMILY SSF53335 25 237 1.61E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_12600 90aadfb082645f30cc665412f87b7fd7 241 Gene3D G3DSA:3.40.50.150 33 230 8.8E-36 T 12-10-2018 UA74_12600 90aadfb082645f30cc665412f87b7fd7 241 Pfam PF13649 Methyltransferase domain 34 126 5.6E-14 T 12-10-2018 UA74_12600 90aadfb082645f30cc665412f87b7fd7 241 Gene3D G3DSA:2.20.25.570 134 197 8.8E-36 T 12-10-2018 UA74_06445 e96cd3680e407ce01b4abbe3d026fd39 448 PIRSF PIRSF005572 1 394 2.1E-107 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 UA74_06445 e96cd3680e407ce01b4abbe3d026fd39 448 Pfam PF00266 Aminotransferase class-V 3 379 1.7E-60 T 12-10-2018 IPR000192 Aminotransferase class V domain UA74_06445 e96cd3680e407ce01b4abbe3d026fd39 448 Gene3D G3DSA:3.40.640.10 13 260 4.2E-136 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_06445 e96cd3680e407ce01b4abbe3d026fd39 448 Gene3D G3DSA:3.90.1150.10 3 378 4.2E-136 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_06445 e96cd3680e407ce01b4abbe3d026fd39 448 SUPERFAMILY SSF53383 2 389 3.9E-91 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_03255 ad25fd47e7b2f61c5d367f435e47f2d1 141 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 130 1.5E-30 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UA74_03255 ad25fd47e7b2f61c5d367f435e47f2d1 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 80 88 4.6E-9 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UA74_03255 ad25fd47e7b2f61c5d367f435e47f2d1 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 4.6E-9 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UA74_03255 ad25fd47e7b2f61c5d367f435e47f2d1 141 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 90 99 4.6E-9 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UA74_03255 ad25fd47e7b2f61c5d367f435e47f2d1 141 SUPERFAMILY SSF81330 10 124 3.27E-27 T 12-10-2018 IPR036019 Gated mechanosensitive channel UA74_03255 ad25fd47e7b2f61c5d367f435e47f2d1 141 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 12-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site UA74_03255 ad25fd47e7b2f61c5d367f435e47f2d1 141 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 129 20.91 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UA74_03255 ad25fd47e7b2f61c5d367f435e47f2d1 141 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 127 2.4E-38 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L UA74_03255 ad25fd47e7b2f61c5d367f435e47f2d1 141 Gene3D G3DSA:1.10.1200.120 1 131 2.3E-39 T 12-10-2018 IPR036019 Gated mechanosensitive channel UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 2 410 2.3E-193 T 12-10-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 PIRSF PIRSF000521 119 160 0.12 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 PIRSF PIRSF000521 2 127 3.2E-5 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 PIRSF PIRSF000521 182 412 2.0E-32 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 412 1.6E-140 T 12-10-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 Pfam PF00202 Aminotransferase class-III 19 409 1.3E-73 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 SUPERFAMILY SSF53383 9 409 8.82E-105 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 Gene3D G3DSA:3.90.1150.10 9 404 6.7E-105 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 Gene3D G3DSA:3.40.640.10 54 314 6.7E-105 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_01835 d46cd62e321c17cd2124fd154dccecbe 417 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 268 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_24625 028d34ef423a3607025b73f37706eebd 656 Gene3D G3DSA:3.30.420.40 5 350 3.1E-96 T 12-10-2018 UA74_24625 028d34ef423a3607025b73f37706eebd 656 Gene3D G3DSA:3.90.640.10 203 290 3.1E-96 T 12-10-2018 UA74_24625 028d34ef423a3607025b73f37706eebd 656 PRINTS PR00301 70kDa heat shock protein signature 30 42 2.2E-7 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_24625 028d34ef423a3607025b73f37706eebd 656 PRINTS PR00301 70kDa heat shock protein signature 177 187 2.2E-7 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_24625 028d34ef423a3607025b73f37706eebd 656 PRINTS PR00301 70kDa heat shock protein signature 2 15 2.2E-7 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_24625 028d34ef423a3607025b73f37706eebd 656 PRINTS PR00301 70kDa heat shock protein signature 309 325 2.2E-7 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_24625 028d34ef423a3607025b73f37706eebd 656 SUPERFAMILY SSF53067 3 156 2.49E-22 T 12-10-2018 UA74_24625 028d34ef423a3607025b73f37706eebd 656 Pfam PF00012 Hsp70 protein 88 350 2.6E-30 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_24625 028d34ef423a3607025b73f37706eebd 656 SUPERFAMILY SSF53067 166 351 2.8E-32 T 12-10-2018 UA74_24625 028d34ef423a3607025b73f37706eebd 656 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 312 326 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_24625 028d34ef423a3607025b73f37706eebd 656 Gene3D G3DSA:3.30.420.40 165 340 3.1E-96 T 12-10-2018 UA74_02925 349c50f67e96e5c3b7c62f0ce5d77bec 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_02925 349c50f67e96e5c3b7c62f0ce5d77bec 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.948 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 UA74_02925 349c50f67e96e5c3b7c62f0ce5d77bec 156 Gene3D G3DSA:1.10.455.10 2 156 7.5E-57 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily UA74_02925 349c50f67e96e5c3b7c62f0ce5d77bec 156 SUPERFAMILY SSF47973 1 149 5.1E-57 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily UA74_02925 349c50f67e96e5c3b7c62f0ce5d77bec 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 5.6E-60 T 12-10-2018 IPR023798 Ribosomal protein S7 domain UA74_02925 349c50f67e96e5c3b7c62f0ce5d77bec 156 PIRSF PIRSF002122 5 156 4.2E-56 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 UA74_02925 349c50f67e96e5c3b7c62f0ce5d77bec 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.2E-65 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 UA74_28840 f9108bc4260047e42baa9e23819f20f2 502 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 48 502 4.6E-123 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase UA74_28840 f9108bc4260047e42baa9e23819f20f2 502 Pfam PF13727 CoA-binding domain 104 234 3.0E-7 T 12-10-2018 UA74_28840 f9108bc4260047e42baa9e23819f20f2 502 Pfam PF02397 Bacterial sugar transferase 309 496 1.8E-66 T 12-10-2018 IPR003362 Bacterial sugar transferase UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 Pfam PF13377 Periplasmic binding protein-like domain 213 372 3.8E-32 T 12-10-2018 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 SMART SM00354 40 110 1.0E-27 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 Gene3D G3DSA:1.10.260.40 31 93 2.1E-23 T 12-10-2018 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 Gene3D G3DSA:3.40.50.2300 204 333 1.7E-59 T 12-10-2018 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 SUPERFAMILY SSF47413 40 98 1.69E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 52 62 6.9E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 42 52 6.9E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 Gene3D G3DSA:3.40.50.2300 94 350 1.7E-59 T 12-10-2018 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 Pfam PF00356 Bacterial regulatory proteins, lacI family 42 87 3.1E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 ProSitePatterns PS00356 LacI-type HTH domain signature. 43 61 - T 12-10-2018 UA74_27825 529a2f1067d4de22c52ea30a245d04a9 373 SUPERFAMILY SSF53822 113 372 2.75E-56 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_01745 4bfdc56d515bc4f8df1848bf60332341 209 SUPERFAMILY SSF53335 6 194 8.21E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_01745 4bfdc56d515bc4f8df1848bf60332341 209 Gene3D G3DSA:3.40.50.150 15 196 8.1E-29 T 12-10-2018 UA74_01745 4bfdc56d515bc4f8df1848bf60332341 209 Pfam PF13649 Methyltransferase domain 44 138 7.9E-18 T 12-10-2018 UA74_08360 f6177db4b49f1616b29a465f00a53722 222 SUPERFAMILY SSF69593 5 218 1.09E-50 T 12-10-2018 UA74_08360 f6177db4b49f1616b29a465f00a53722 222 SMART SM00563 34 153 7.7E-35 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_08360 f6177db4b49f1616b29a465f00a53722 222 Pfam PF01553 Acyltransferase 20 150 3.3E-26 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 SUPERFAMILY SSF46785 11 79 9.9E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 PRINTS PR01467 Bacterial arginine repressor signature 46 61 1.1E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 PRINTS PR01467 Bacterial arginine repressor signature 103 116 1.1E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 PRINTS PR01467 Bacterial arginine repressor signature 30 43 1.1E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 PRINTS PR01467 Bacterial arginine repressor signature 133 148 1.1E-25 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 103 160 8.0E-19 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 Pfam PF02863 Arginine repressor, C-terminal domain 95 160 2.5E-24 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 Pfam PF01316 Arginine repressor, DNA binding domain 12 79 2.2E-22 T 12-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 TIGRFAM TIGR01529 argR_whole: arginine repressor 14 163 2.1E-46 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 Hamap MF_00173 Arginine repressor [argR]. 1 167 59.44 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 Gene3D G3DSA:1.10.10.10 2 83 1.4E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 SUPERFAMILY SSF55252 95 162 6.15E-18 T 12-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 UA74_21610 269b849c0546e112bbbb2652b1295cd8 196 Gene3D G3DSA:3.30.1360.40 86 164 8.7E-30 T 12-10-2018 UA74_02720 bf2f6c74c11941273399228ffad276b6 134 SUPERFAMILY SSF55298 20 133 1.48E-25 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_02720 bf2f6c74c11941273399228ffad276b6 134 Pfam PF01042 Endoribonuclease L-PSP 18 133 1.2E-17 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UA74_02720 bf2f6c74c11941273399228ffad276b6 134 Gene3D G3DSA:3.30.1330.40 2 134 1.6E-28 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_02685 2cf44624443f1c35137a4744add96f31 232 Pfam PF00005 ABC transporter 22 170 3.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_02685 2cf44624443f1c35137a4744add96f31 232 SUPERFAMILY SSF52540 4 223 2.13E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_02685 2cf44624443f1c35137a4744add96f31 232 Gene3D G3DSA:3.40.50.300 1 224 7.9E-66 T 12-10-2018 UA74_02685 2cf44624443f1c35137a4744add96f31 232 SMART SM00382 31 218 2.6E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_02685 2cf44624443f1c35137a4744add96f31 232 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 Gene3D G3DSA:3.40.630.10 120 432 8.1E-96 T 12-10-2018 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 174 196 - T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 312 322 - T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 SMART SM00631 126 408 9.0E-86 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 Pfam PF00246 Zinc carboxypeptidase 134 406 4.1E-63 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 SUPERFAMILY SSF53187 123 421 1.26E-78 T 12-10-2018 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 174 188 7.2E-13 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 152 164 7.2E-13 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 309 322 7.2E-13 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_09850 b552a944fff89c47a5dcb0993d7745d0 434 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 250 258 7.2E-13 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_19060 2ed61db0427b3d9df1645135ad931904 113 SUPERFAMILY SSF46785 5 106 5.93E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_19060 2ed61db0427b3d9df1645135ad931904 113 Pfam PF03551 Transcriptional regulator PadR-like family 17 89 2.0E-20 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_19060 2ed61db0427b3d9df1645135ad931904 113 Gene3D G3DSA:1.10.10.10 3 112 4.1E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17955 7ca1d9ed5573b5cc0d28d432ce61b127 286 SMART SM01043 99 243 4.3E-44 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_17955 7ca1d9ed5573b5cc0d28d432ce61b127 286 Gene3D G3DSA:1.25.40.10 97 258 6.2E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_17955 7ca1d9ed5573b5cc0d28d432ce61b127 286 SUPERFAMILY SSF46894 10 92 7.94E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_17955 7ca1d9ed5573b5cc0d28d432ce61b127 286 SUPERFAMILY SSF48452 94 259 3.46E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_17955 7ca1d9ed5573b5cc0d28d432ce61b127 286 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 92 8.4E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_17955 7ca1d9ed5573b5cc0d28d432ce61b127 286 Pfam PF03704 Bacterial transcriptional activator domain 99 243 5.9E-39 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_17955 7ca1d9ed5573b5cc0d28d432ce61b127 286 Gene3D G3DSA:1.10.10.10 1 95 2.4E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17955 7ca1d9ed5573b5cc0d28d432ce61b127 286 SMART SM00862 18 92 9.9E-8 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_29665 9b6e25b2576d161b04c34213fdbb8605 278 Pfam PF04011 LemA family 7 184 2.9E-61 T 12-10-2018 IPR007156 LemA UA74_29665 9b6e25b2576d161b04c34213fdbb8605 278 SUPERFAMILY SSF140478 26 178 9.68E-47 T 12-10-2018 IPR023353 LemA-like domain superfamily UA74_29665 9b6e25b2576d161b04c34213fdbb8605 278 Gene3D G3DSA:1.20.1440.20 17 187 8.4E-57 T 12-10-2018 IPR023353 LemA-like domain superfamily UA74_26330 4c7e1328a546b3df049390c9f340d6ac 510 SUPERFAMILY SSF48557 2 503 2.35E-176 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 UA74_26330 4c7e1328a546b3df049390c9f340d6ac 510 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 140 156 - T 12-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 UA74_26330 4c7e1328a546b3df049390c9f340d6ac 510 Gene3D G3DSA:1.20.200.10 200 509 3.4E-109 T 12-10-2018 UA74_26330 4c7e1328a546b3df049390c9f340d6ac 510 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 7 506 3.0E-193 T 12-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 UA74_26330 4c7e1328a546b3df049390c9f340d6ac 510 Gene3D G3DSA:1.10.275.10 2 199 1.4E-63 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal UA74_26330 4c7e1328a546b3df049390c9f340d6ac 510 Pfam PF00221 Aromatic amino acid lyase 12 473 1.0E-176 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 UA74_22085 65a5d21565e2101c2d61a829980f4151 586 SUPERFAMILY SSF89372 222 414 2.75E-12 T 12-10-2018 UA74_22085 65a5d21565e2101c2d61a829980f4151 586 SUPERFAMILY SSF89372 379 563 7.06E-14 T 12-10-2018 UA74_21520 05f9e8bed56e92842a582b943f7c0679 229 Gene3D G3DSA:3.90.79.10 22 228 2.3E-60 T 12-10-2018 UA74_21520 05f9e8bed56e92842a582b943f7c0679 229 Pfam PF00293 NUDIX domain 63 176 1.0E-13 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_21520 05f9e8bed56e92842a582b943f7c0679 229 SUPERFAMILY SSF55811 28 199 1.02E-42 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_02375 8d8c8549360991952b44dfbc93bc0fc8 210 Gene3D G3DSA:3.40.50.1240 2 198 2.4E-28 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_02375 8d8c8549360991952b44dfbc93bc0fc8 210 PIRSF PIRSF000709 1 77 0.0062 T 12-10-2018 UA74_02375 8d8c8549360991952b44dfbc93bc0fc8 210 SUPERFAMILY SSF53254 6 196 9.69E-36 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_02375 8d8c8549360991952b44dfbc93bc0fc8 210 SMART SM00855 6 158 2.1E-16 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_02375 8d8c8549360991952b44dfbc93bc0fc8 210 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 191 4.5E-34 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_22050 247380fc146bcd7a5a8767853217cdda 116 SUPERFAMILY SSF51197 14 116 2.79E-10 T 12-10-2018 UA74_22050 247380fc146bcd7a5a8767853217cdda 116 Gene3D G3DSA:3.60.130.10 2 116 4.2E-8 T 12-10-2018 UA74_22050 247380fc146bcd7a5a8767853217cdda 116 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 7 116 1.1E-8 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 UA74_23545 2e4d248c6b7b30a4ca7c65d286fedbe5 370 Gene3D G3DSA:3.30.420.150 108 290 4.4E-58 T 12-10-2018 UA74_23545 2e4d248c6b7b30a4ca7c65d286fedbe5 370 SUPERFAMILY SSF53067 132 303 4.53E-28 T 12-10-2018 UA74_23545 2e4d248c6b7b30a4ca7c65d286fedbe5 370 Gene3D G3DSA:3.30.420.40 4 297 4.4E-58 T 12-10-2018 UA74_23545 2e4d248c6b7b30a4ca7c65d286fedbe5 370 SUPERFAMILY SSF53067 3 125 5.89E-20 T 12-10-2018 UA74_23545 2e4d248c6b7b30a4ca7c65d286fedbe5 370 Pfam PF02541 Ppx/GppA phosphatase family 33 303 2.3E-49 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 UA74_04160 360884fe8e88ecec536d75b8cd13a390 88 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 23 83 13.877 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_04160 360884fe8e88ecec536d75b8cd13a390 88 Pfam PF02609 Exonuclease VII small subunit 24 74 1.7E-17 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_04160 360884fe8e88ecec536d75b8cd13a390 88 PIRSF PIRSF006488 9 88 3.8E-23 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_04160 360884fe8e88ecec536d75b8cd13a390 88 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 24 77 2.5E-20 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_04160 360884fe8e88ecec536d75b8cd13a390 88 Gene3D G3DSA:1.10.287.1040 17 87 3.7E-15 T 12-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 UA74_04160 360884fe8e88ecec536d75b8cd13a390 88 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 21 62 5.0E-13 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UA74_04160 360884fe8e88ecec536d75b8cd13a390 88 SUPERFAMILY SSF116842 18 77 2.48E-16 T 12-10-2018 UA74_21595 b238d05574598349ab8b76876b3faf3a 226 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 17 209 7.5E-55 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_21595 b238d05574598349ab8b76876b3faf3a 226 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 12 209 30.747 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_21595 b238d05574598349ab8b76876b3faf3a 226 Gene3D G3DSA:3.10.300.10 13 220 3.9E-60 T 12-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_21595 b238d05574598349ab8b76876b3faf3a 226 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 23 205 4.7E-59 T 12-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UA74_21595 b238d05574598349ab8b76876b3faf3a 226 SUPERFAMILY SSF50486 16 215 2.82E-58 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 UA74_25810 671125db8c67ebda3257b42df4338574 337 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 5 326 36.742 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 322 2.6E-50 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 PIRSF PIRSF000114 2 335 7.1E-101 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 SUPERFAMILY SSF51735 6 181 3.16E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25810 671125db8c67ebda3257b42df4338574 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 1.1E-46 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 1.1E-46 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 59 86 1.1E-46 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 1.1E-46 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 1.1E-46 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 1.1E-46 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 SUPERFAMILY SSF48179 183 335 2.27E-51 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_25810 671125db8c67ebda3257b42df4338574 337 Gene3D G3DSA:1.10.1040.10 192 337 1.4E-48 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_25810 671125db8c67ebda3257b42df4338574 337 Gene3D G3DSA:3.40.50.720 1 190 9.7E-64 T 12-10-2018 UA74_25810 671125db8c67ebda3257b42df4338574 337 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 7 162 1.5E-52 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25810 671125db8c67ebda3257b42df4338574 337 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UA74_25490 914e10fbe439c61987ddfe444838c9d4 243 Gene3D G3DSA:3.30.1380.10 117 242 3.5E-34 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_25490 914e10fbe439c61987ddfe444838c9d4 243 Pfam PF08291 Peptidase M15 117 227 7.3E-22 T 12-10-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 UA74_25490 914e10fbe439c61987ddfe444838c9d4 243 Pfam PF01471 Putative peptidoglycan binding domain 44 105 4.6E-12 T 12-10-2018 IPR002477 Peptidoglycan binding-like UA74_25490 914e10fbe439c61987ddfe444838c9d4 243 SUPERFAMILY SSF55166 117 230 3.92E-28 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_25490 914e10fbe439c61987ddfe444838c9d4 243 Gene3D G3DSA:1.10.101.10 31 115 7.6E-26 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UA74_25490 914e10fbe439c61987ddfe444838c9d4 243 SUPERFAMILY SSF47090 33 108 1.88E-17 T 12-10-2018 IPR036365 PGBD-like superfamily UA74_22215 1d8bdf10c82bb1360506409c39ec6126 334 Gene3D G3DSA:3.20.20.30 1 328 2.7E-77 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_22215 1d8bdf10c82bb1360506409c39ec6126 334 SUPERFAMILY SSF51679 2 328 1.7E-70 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_22215 1d8bdf10c82bb1360506409c39ec6126 334 Pfam PF00296 Luciferase-like monooxygenase 4 288 4.5E-49 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 Hamap MF_00020 Acetate kinase [ackA]. 1 387 116.257 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 20 31 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 Pfam PF00871 Acetokinase family 54 378 6.4E-85 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 193 210 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 165 178 9.8E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 193 214 9.8E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 366 378 9.8E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 314 330 9.8E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 20 31 9.8E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 PRINTS PR00471 Acetate kinase family signature 292 305 9.8E-32 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 Gene3D G3DSA:3.30.420.40 18 187 1.9E-48 T 12-10-2018 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 Gene3D G3DSA:3.30.420.40 190 387 1.1E-60 T 12-10-2018 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 SUPERFAMILY SSF53067 150 384 2.13E-63 T 12-10-2018 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 PIRSF PIRSF000722 17 60 0.0029 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 PIRSF PIRSF000722 46 387 1.1E-98 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UA74_11775 6681461eb2714bcb1ce70c602dd94a38 387 SUPERFAMILY SSF53067 18 186 1.62E-42 T 12-10-2018 UA74_21980 27268c9cf54fdb8addb5ca8cad340ecf 307 Pfam PF10099 Anti-sigma-K factor rskA 65 303 1.2E-14 T 12-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 UA74_21980 27268c9cf54fdb8addb5ca8cad340ecf 307 Gene3D G3DSA:1.10.10.1320 7 79 2.6E-12 T 12-10-2018 UA74_02575 0ca3489ee747005706a9b98deeb64b47 473 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 70 473 1.5E-163 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02575 0ca3489ee747005706a9b98deeb64b47 473 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 107 118 - T 12-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02575 0ca3489ee747005706a9b98deeb64b47 473 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 185 473 1.7E-105 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02575 0ca3489ee747005706a9b98deeb64b47 473 Gene3D G3DSA:1.10.645.20 69 473 1.4E-158 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02575 0ca3489ee747005706a9b98deeb64b47 473 SUPERFAMILY SSF56762 80 473 1.57E-115 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02575 0ca3489ee747005706a9b98deeb64b47 473 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 66 473 46.594 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_26775 53fae4498a06774a4f4c1c74607cb30b 427 Gene3D G3DSA:3.40.50.20 1 108 2.5E-29 T 12-10-2018 UA74_26775 53fae4498a06774a4f4c1c74607cb30b 427 SUPERFAMILY SSF51246 340 418 2.9E-17 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UA74_26775 53fae4498a06774a4f4c1c74607cb30b 427 SUPERFAMILY SSF52440 3 95 3.45E-22 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_26775 53fae4498a06774a4f4c1c74607cb30b 427 Pfam PF02222 ATP-grasp domain 293 314 2.3E-7 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UA74_26775 53fae4498a06774a4f4c1c74607cb30b 427 Pfam PF02222 ATP-grasp domain 109 257 2.7E-37 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UA74_26775 53fae4498a06774a4f4c1c74607cb30b 427 SUPERFAMILY SSF56059 99 334 5.23E-44 T 12-10-2018 UA74_26775 53fae4498a06774a4f4c1c74607cb30b 427 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 3 396 38.945 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 UA74_26775 53fae4498a06774a4f4c1c74607cb30b 427 Gene3D G3DSA:3.30.1490.20 111 180 2.6E-16 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 293 1.8E-16 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 136 1.9E-9 T 12-10-2018 UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 17 36 1.9E-9 T 12-10-2018 UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 1.9E-9 T 12-10-2018 UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 SUPERFAMILY SSF51905 9 313 2.28E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 Gene3D G3DSA:3.50.50.60 16 308 6.0E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 Gene3D G3DSA:3.50.50.60 132 242 6.0E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 16 38 4.6E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 141 153 4.6E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 4.6E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 156 180 4.6E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_16790 ec49be7dfd06dfea90dfb89252dc0508 334 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 278 296 4.6E-16 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_20045 4ff36f72701cf46fd6dd94f9d571424a 477 Gene3D G3DSA:1.10.10.10 336 456 3.9E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20045 4ff36f72701cf46fd6dd94f9d571424a 477 SUPERFAMILY SSF46785 338 424 5.56E-7 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_21035 30d2bba6b645bbcc53443195bad3e954 255 Gene3D G3DSA:3.40.50.720 5 236 1.5E-36 T 12-10-2018 UA74_21035 30d2bba6b645bbcc53443195bad3e954 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21035 30d2bba6b645bbcc53443195bad3e954 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21035 30d2bba6b645bbcc53443195bad3e954 255 Pfam PF00106 short chain dehydrogenase 14 189 2.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21035 30d2bba6b645bbcc53443195bad3e954 255 SUPERFAMILY SSF51735 7 238 3.85E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_21035 30d2bba6b645bbcc53443195bad3e954 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_01640 5583a0afe025b88b34ebef6718f36d42 103 Gene3D G3DSA:3.30.70.100 1 99 6.0E-38 T 12-10-2018 UA74_01640 5583a0afe025b88b34ebef6718f36d42 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 73 5.7E-19 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_01640 5583a0afe025b88b34ebef6718f36d42 103 SUPERFAMILY SSF54909 1 96 1.86E-24 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_08010 077222451b469aa5dabf257401a56816 350 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_08010 077222451b469aa5dabf257401a56816 350 Gene3D G3DSA:2.40.50.100 277 343 1.4E-5 T 12-10-2018 UA74_08010 077222451b469aa5dabf257401a56816 350 SUPERFAMILY SSF52540 15 239 3.69E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08010 077222451b469aa5dabf257401a56816 350 Gene3D G3DSA:3.40.50.300 16 243 2.2E-65 T 12-10-2018 UA74_08010 077222451b469aa5dabf257401a56816 350 Gene3D G3DSA:2.40.50.140 258 345 1.4E-5 T 12-10-2018 UA74_08010 077222451b469aa5dabf257401a56816 350 SMART SM00382 25 215 1.4E-21 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_08010 077222451b469aa5dabf257401a56816 350 Pfam PF03459 TOBE domain 293 345 2.2E-6 T 12-10-2018 IPR005116 Transport-associated OB, type 1 UA74_08010 077222451b469aa5dabf257401a56816 350 SUPERFAMILY SSF50331 240 348 1.29E-12 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UA74_08010 077222451b469aa5dabf257401a56816 350 Pfam PF00005 ABC transporter 19 166 4.6E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_05185 2d6c20f1bece579e4650bc8e56f40cdb 70 Pfam PF03621 MbtH-like protein 2 51 1.0E-19 T 12-10-2018 IPR005153 MbtH-like domain UA74_05185 2d6c20f1bece579e4650bc8e56f40cdb 70 SUPERFAMILY SSF160582 2 67 2.62E-26 T 12-10-2018 IPR038020 MbtH-like domain superfamily UA74_05185 2d6c20f1bece579e4650bc8e56f40cdb 70 SMART SM00923 2 52 1.8E-18 T 12-10-2018 IPR005153 MbtH-like domain UA74_05185 2d6c20f1bece579e4650bc8e56f40cdb 70 Gene3D G3DSA:3.90.820.10 1 70 4.2E-30 T 12-10-2018 UA74_13575 da30513827a99476538729c4b628812c 430 SUPERFAMILY SSF53756 1 397 1.91E-70 T 12-10-2018 UA74_13575 da30513827a99476538729c4b628812c 430 Gene3D G3DSA:3.40.50.2000 1 397 1.0E-96 T 12-10-2018 UA74_13575 da30513827a99476538729c4b628812c 430 Pfam PF06722 Protein of unknown function (DUF1205) 200 292 1.9E-15 T 12-10-2018 IPR010610 Domain of unknown function DUF1205 UA74_13575 da30513827a99476538729c4b628812c 430 Gene3D G3DSA:3.40.50.2000 219 392 1.0E-96 T 12-10-2018 UA74_18530 b0fe4b1ce3672740c89f07abecfe4e24 394 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 156 367 5.5E-15 T 12-10-2018 IPR005079 Peptidase C45 UA74_18530 b0fe4b1ce3672740c89f07abecfe4e24 394 SUPERFAMILY SSF56235 177 365 2.08E-12 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_18530 b0fe4b1ce3672740c89f07abecfe4e24 394 Gene3D G3DSA:3.60.60.10 93 380 1.1E-34 T 12-10-2018 UA74_05600 c6c3c3c68026f33ec465cdf11f7c4279 413 Pfam PF02515 CoA-transferase family III 17 390 1.0E-129 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 UA74_05600 c6c3c3c68026f33ec465cdf11f7c4279 413 SUPERFAMILY SSF89796 14 413 4.19E-134 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily UA74_05600 c6c3c3c68026f33ec465cdf11f7c4279 413 Gene3D G3DSA:3.40.50.10540 16 407 4.4E-132 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily UA74_05600 c6c3c3c68026f33ec465cdf11f7c4279 413 Gene3D G3DSA:3.30.1540.10 247 338 4.4E-132 T 12-10-2018 UA74_21135 9842bf54f88b0b82ae30664cee03adef 51 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 51 12.837 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21135 9842bf54f88b0b82ae30664cee03adef 51 Pfam PF01783 Ribosomal L32p protein family 2 30 8.7E-11 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21135 9842bf54f88b0b82ae30664cee03adef 51 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 33 2.2E-11 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21135 9842bf54f88b0b82ae30664cee03adef 51 SUPERFAMILY SSF57829 1 37 5.19E-9 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 UA74_24755 1cdc0d62666e40fbab449399df1e0c79 88 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 51 2.5E-10 T 12-10-2018 UA74_24755 1cdc0d62666e40fbab449399df1e0c79 88 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 8 68 5.7E-10 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM UA74_24755 1cdc0d62666e40fbab449399df1e0c79 88 Gene3D G3DSA:3.40.1620.10 4 42 9.9E-8 T 12-10-2018 UA74_24755 1cdc0d62666e40fbab449399df1e0c79 88 SUPERFAMILY SSF143120 7 70 7.98E-9 T 12-10-2018 IPR036165 YefM-like superfamily UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 ProSitePatterns PS00622 LuxR-type HTH domain signature. 151 178 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 Pfam PF00072 Response regulator receiver domain 4 115 1.5E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 SUPERFAMILY SSF52172 3 122 1.85E-16 T 12-10-2018 IPR011006 CheY-like superfamily UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 SUPERFAMILY SSF46894 125 197 1.94E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 Gene3D G3DSA:1.10.10.10 129 198 5.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 SMART SM00421 134 191 6.1E-25 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 189 2.2E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 Gene3D G3DSA:3.40.50.2300 2 128 5.9E-19 T 12-10-2018 UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 8.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 8.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 8.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_27895 a09c3f1cc198baa3a2371798600cb34b 198 SMART SM00448 2 115 9.9E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_02175 10dc40698a2b538036d53908da356a17 410 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 410 66.375 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_02175 10dc40698a2b538036d53908da356a17 410 Gene3D G3DSA:3.30.465.10 135 280 5.9E-39 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_02175 10dc40698a2b538036d53908da356a17 410 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 268 406 1.4E-36 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_02175 10dc40698a2b538036d53908da356a17 410 SUPERFAMILY SSF56176 140 242 4.31E-21 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_02175 10dc40698a2b538036d53908da356a17 410 SUPERFAMILY SSF56176 16 83 6.54E-11 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_02175 10dc40698a2b538036d53908da356a17 410 Gene3D G3DSA:3.30.43.10 12 84 2.7E-22 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 UA74_02175 10dc40698a2b538036d53908da356a17 410 Pfam PF01565 FAD binding domain 141 208 1.4E-9 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_02175 10dc40698a2b538036d53908da356a17 410 Pfam PF01565 FAD binding domain 34 83 4.7E-7 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_02175 10dc40698a2b538036d53908da356a17 410 SUPERFAMILY SSF56194 266 407 9.55E-29 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_02175 10dc40698a2b538036d53908da356a17 410 Gene3D G3DSA:3.90.78.10 286 409 1.3E-32 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_16115 7fec27becfb5831cc1ba04ea2314b8e1 293 Gene3D G3DSA:1.20.81.30 92 209 2.9E-5 T 12-10-2018 UA74_16115 7fec27becfb5831cc1ba04ea2314b8e1 293 Pfam PF00482 Type II secretion system (T2SS), protein F 106 231 1.9E-5 T 12-10-2018 IPR018076 Type II secretion system F domain UA74_05200 e40cda602db75ce495ee0d7541d86298 317 Pfam PF00487 Fatty acid desaturase 43 286 3.0E-27 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_25815 065069d50ab95374dcc3e2051416fb79 259 Pfam PF01553 Acyltransferase 41 167 8.2E-27 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_25815 065069d50ab95374dcc3e2051416fb79 259 SMART SM00563 53 171 7.0E-34 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_25815 065069d50ab95374dcc3e2051416fb79 259 SUPERFAMILY SSF69593 39 235 6.28E-45 T 12-10-2018 UA74_28290 1160ef39ee226836d886896a449d8d6d 751 Pfam PF00005 ABC transporter 455 603 3.0E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_28290 1160ef39ee226836d886896a449d8d6d 751 Gene3D G3DSA:1.20.1560.10 66 401 3.3E-68 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_28290 1160ef39ee226836d886896a449d8d6d 751 ProSitePatterns PS00211 ABC transporters family signature. 576 590 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_28290 1160ef39ee226836d886896a449d8d6d 751 SUPERFAMILY SSF90123 85 393 3.01E-66 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_28290 1160ef39ee226836d886896a449d8d6d 751 Pfam PF00664 ABC transporter transmembrane region 97 367 2.4E-38 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_28290 1160ef39ee226836d886896a449d8d6d 751 SMART SM00382 464 650 2.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28290 1160ef39ee226836d886896a449d8d6d 751 SUPERFAMILY SSF52540 412 672 4.8E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28290 1160ef39ee226836d886896a449d8d6d 751 Gene3D G3DSA:3.40.50.300 406 674 1.9E-79 T 12-10-2018 UA74_14280 42de8b378396628a2189c582d319ffb2 424 Pfam PF00067 Cytochrome P450 198 394 4.6E-21 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 SUPERFAMILY SSF48264 16 423 8.12E-92 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 Gene3D G3DSA:1.10.630.10 6 424 2.8E-124 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 106 117 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 292 303 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 310 337 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 364 373 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 373 384 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 338 353 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 158 174 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 210 232 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14280 42de8b378396628a2189c582d319ffb2 424 PRINTS PR00359 B-class P450 signature 175 190 1.6E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_14130 9547c4b7d89c1676ea40db0cef891415 275 Pfam PF00296 Luciferase-like monooxygenase 13 247 1.6E-42 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_14130 9547c4b7d89c1676ea40db0cef891415 275 SUPERFAMILY SSF51679 11 264 1.31E-47 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_14130 9547c4b7d89c1676ea40db0cef891415 275 Gene3D G3DSA:3.20.20.30 2 273 1.5E-55 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_07875 11b816c8184f8c31f8eb30ed13ac7bdc 152 Gene3D G3DSA:3.10.129.10 2 143 4.7E-31 T 12-10-2018 UA74_07875 11b816c8184f8c31f8eb30ed13ac7bdc 152 Pfam PF13279 Thioesterase-like superfamily 11 122 1.5E-9 T 12-10-2018 UA74_07875 11b816c8184f8c31f8eb30ed13ac7bdc 152 SUPERFAMILY SSF54637 4 136 4.41E-27 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_05070 5a25bbb3229c6db0e8c9fa1b49ff4fa2 316 SUPERFAMILY SSF53448 3 216 4.71E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_05070 5a25bbb3229c6db0e8c9fa1b49ff4fa2 316 Gene3D G3DSA:3.90.550.10 1 231 1.2E-34 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_05070 5a25bbb3229c6db0e8c9fa1b49ff4fa2 316 Pfam PF00535 Glycosyl transferase family 2 9 139 2.3E-20 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_18320 278443f11675fa017763e49b28f470fc 529 Gene3D G3DSA:3.40.50.300 278 528 2.1E-46 T 12-10-2018 UA74_18320 278443f11675fa017763e49b28f470fc 529 SUPERFAMILY SSF52540 18 242 3.92E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18320 278443f11675fa017763e49b28f470fc 529 SUPERFAMILY SSF52540 290 496 3.4E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18320 278443f11675fa017763e49b28f470fc 529 Gene3D G3DSA:3.40.50.300 5 264 6.0E-57 T 12-10-2018 UA74_18320 278443f11675fa017763e49b28f470fc 529 Pfam PF00005 ABC transporter 34 184 7.8E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_18320 278443f11675fa017763e49b28f470fc 529 SMART SM00382 43 240 2.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_18320 278443f11675fa017763e49b28f470fc 529 SMART SM00382 299 493 0.0049 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_18320 278443f11675fa017763e49b28f470fc 529 Pfam PF00005 ABC transporter 290 444 1.3E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_18320 278443f11675fa017763e49b28f470fc 529 ProSitePatterns PS00211 ABC transporters family signature. 417 431 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_13700 9a9800056b70040002655e86973b8540 191 SUPERFAMILY SSF160904 2 170 1.44E-34 T 12-10-2018 UA74_13700 9a9800056b70040002655e86973b8540 191 Gene3D G3DSA:1.10.3300.10 2 173 4.1E-43 T 12-10-2018 IPR023286 ABATE domain superfamily UA74_13700 9a9800056b70040002655e86973b8540 191 Pfam PF11706 CGNR zinc finger 129 171 1.5E-14 T 12-10-2018 IPR021005 Zinc finger, CGNR UA74_15210 2eed6139e4feeaecd25247821b062bff 144 Pfam PF08818 Domain of unknown function (DU1801) 52 143 1.9E-6 T 12-10-2018 IPR014922 Domain of unknown function DUF1801 UA74_15210 2eed6139e4feeaecd25247821b062bff 144 SUPERFAMILY SSF159888 44 126 7.32E-10 T 12-10-2018 UA74_05385 357cb77a7de5a85b18ddf2c3bd266998 145 SMART SM00347 28 127 3.1E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05385 357cb77a7de5a85b18ddf2c3bd266998 145 Pfam PF01047 MarR family 40 91 8.8E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05385 357cb77a7de5a85b18ddf2c3bd266998 145 SUPERFAMILY SSF46785 7 139 8.49E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_05385 357cb77a7de5a85b18ddf2c3bd266998 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 4.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05385 357cb77a7de5a85b18ddf2c3bd266998 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 4.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05385 357cb77a7de5a85b18ddf2c3bd266998 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 4.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05385 357cb77a7de5a85b18ddf2c3bd266998 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 4.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05385 357cb77a7de5a85b18ddf2c3bd266998 145 Gene3D G3DSA:1.10.10.10 3 139 9.1E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_30300 d0ca254113657cae3cdeac159be1899a 185 Gene3D G3DSA:3.30.300.20 38 119 9.9E-14 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_30300 d0ca254113657cae3cdeac159be1899a 185 SUPERFAMILY SSF82708 136 183 1.12E-9 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 UA74_30300 d0ca254113657cae3cdeac159be1899a 185 Pfam PF01424 R3H domain 128 181 1.1E-13 T 12-10-2018 IPR001374 R3H domain GO:0003676 UA74_30300 d0ca254113657cae3cdeac159be1899a 185 SMART SM00393 105 184 8.2E-20 T 12-10-2018 IPR001374 R3H domain GO:0003676 UA74_30300 d0ca254113657cae3cdeac159be1899a 185 Gene3D G3DSA:3.30.1370.50 120 185 6.4E-19 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 UA74_11425 e47bf35ab90acb12bb00c3207d7cfb77 465 Gene3D G3DSA:3.30.465.10 352 434 1.6E-22 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_11425 e47bf35ab90acb12bb00c3207d7cfb77 465 SMART SM01091 358 436 6.2E-26 T 12-10-2018 IPR005170 Transporter-associated domain UA74_11425 e47bf35ab90acb12bb00c3207d7cfb77 465 SUPERFAMILY SSF54631 212 351 5.31E-24 T 12-10-2018 UA74_11425 e47bf35ab90acb12bb00c3207d7cfb77 465 Pfam PF03471 Transporter associated domain 361 435 1.7E-23 T 12-10-2018 IPR005170 Transporter-associated domain UA74_11425 e47bf35ab90acb12bb00c3207d7cfb77 465 Gene3D G3DSA:3.10.580.10 202 351 1.0E-40 T 12-10-2018 UA74_11425 e47bf35ab90acb12bb00c3207d7cfb77 465 Pfam PF01595 Domain of unknown function DUF21 13 205 7.8E-34 T 12-10-2018 IPR002550 CNNM, transmembrane domain UA74_11425 e47bf35ab90acb12bb00c3207d7cfb77 465 SUPERFAMILY SSF56176 356 442 1.15E-23 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_22270 8b371ecbfad265f9522c99850ed5ddb3 795 SUPERFAMILY SSF51445 29 380 1.24E-58 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_22270 8b371ecbfad265f9522c99850ed5ddb3 795 Pfam PF01301 Glycosyl hydrolases family 35 39 381 4.1E-46 T 12-10-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_22270 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 354 370 1.3E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_22270 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 115 134 1.3E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_22270 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 39 56 1.3E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_22270 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 169 184 1.3E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_22270 8b371ecbfad265f9522c99850ed5ddb3 795 PRINTS PR00742 Glycosyl hydrolase family 35 signature 60 78 1.3E-18 T 12-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UA74_22270 8b371ecbfad265f9522c99850ed5ddb3 795 Gene3D G3DSA:3.20.20.80 26 390 2.8E-92 T 12-10-2018 UA74_27680 03b6651349e5475815463e9d77566dee 392 Gene3D G3DSA:3.40.50.261 232 390 1.7E-45 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_27680 03b6651349e5475815463e9d77566dee 392 SUPERFAMILY SSF52210 231 388 1.1E-40 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_27680 03b6651349e5475815463e9d77566dee 392 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 388 4.7E-129 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_27680 03b6651349e5475815463e9d77566dee 392 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_27680 03b6651349e5475815463e9d77566dee 392 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 389 39.009 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_27680 03b6651349e5475815463e9d77566dee 392 Gene3D G3DSA:3.30.470.20 3 220 1.3E-81 T 12-10-2018 UA74_27680 03b6651349e5475815463e9d77566dee 392 SUPERFAMILY SSF56059 3 228 4.66E-71 T 12-10-2018 UA74_27680 03b6651349e5475815463e9d77566dee 392 PIRSF PIRSF001554 1 391 1.1E-138 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_27680 03b6651349e5475815463e9d77566dee 392 Pfam PF00549 CoA-ligase 256 368 8.9E-13 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UA74_27680 03b6651349e5475815463e9d77566dee 392 Gene3D G3DSA:3.30.1490.20 21 96 1.3E-81 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_27680 03b6651349e5475815463e9d77566dee 392 Pfam PF08442 ATP-grasp domain 2 194 6.3E-71 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00385 P450 superfamily signature 237 254 5.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00385 P450 superfamily signature 339 348 5.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00385 P450 superfamily signature 272 283 5.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00385 P450 superfamily signature 348 359 5.7E-8 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 Pfam PF00067 Cytochrome P450 185 369 3.5E-30 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 SUPERFAMILY SSF48264 12 399 1.03E-97 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 Gene3D G3DSA:1.10.630.10 9 399 4.9E-122 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 94 105 1.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 195 217 1.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 158 173 1.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 141 157 1.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 348 359 1.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 339 348 1.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 272 283 1.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 318 333 1.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 PRINTS PR00359 B-class P450 signature 290 317 1.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17245 69a79b8e817315574a6cdf633eed216a 399 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_26540 a99469fb09b4694f848815a831629e9d 260 SMART SM00448 38 148 2.9E-46 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_26540 a99469fb09b4694f848815a831629e9d 260 Gene3D G3DSA:3.40.50.2300 35 160 1.6E-38 T 12-10-2018 UA74_26540 a99469fb09b4694f848815a831629e9d 260 Gene3D G3DSA:1.10.10.10 161 260 4.8E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26540 a99469fb09b4694f848815a831629e9d 260 Pfam PF00072 Response regulator receiver domain 40 149 6.4E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_26540 a99469fb09b4694f848815a831629e9d 260 Pfam PF00486 Transcriptional regulatory protein, C terminal 181 256 5.5E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_26540 a99469fb09b4694f848815a831629e9d 260 SMART SM00862 181 257 1.1E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_26540 a99469fb09b4694f848815a831629e9d 260 SUPERFAMILY SSF52172 38 214 2.85E-44 T 12-10-2018 IPR011006 CheY-like superfamily UA74_19860 445e41b059cd76fe50602883431c83c4 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 2.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_19860 445e41b059cd76fe50602883431c83c4 239 Gene3D G3DSA:1.10.357.10 2 234 2.3E-58 T 12-10-2018 UA74_19860 445e41b059cd76fe50602883431c83c4 239 SUPERFAMILY SSF46689 8 81 2.05E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_19860 445e41b059cd76fe50602883431c83c4 239 SUPERFAMILY SSF48498 90 225 3.56E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_01775 73c55037b61a5024451596128cf181a0 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 291 2.0E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_01775 73c55037b61a5024451596128cf181a0 300 Gene3D G3DSA:1.10.3720.10 20 287 1.5E-59 T 12-10-2018 IPR035906 MetI-like superfamily UA74_01775 73c55037b61a5024451596128cf181a0 300 SUPERFAMILY SSF161098 24 300 1.68E-68 T 12-10-2018 IPR035906 MetI-like superfamily UA74_03750 33909874899108ac0ffbea3207202ad7 319 SUPERFAMILY SSF53067 133 317 5.5E-35 T 12-10-2018 UA74_03750 33909874899108ac0ffbea3207202ad7 319 Gene3D G3DSA:3.30.420.150 130 318 3.7E-60 T 12-10-2018 UA74_03750 33909874899108ac0ffbea3207202ad7 319 SUPERFAMILY SSF53067 3 127 5.61E-35 T 12-10-2018 UA74_03750 33909874899108ac0ffbea3207202ad7 319 Gene3D G3DSA:3.30.420.40 1 127 6.6E-47 T 12-10-2018 UA74_03750 33909874899108ac0ffbea3207202ad7 319 Pfam PF02541 Ppx/GppA phosphatase family 26 314 9.1E-72 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 UA74_10180 8898e45e32b59c0de631d5d267468e8e 236 SUPERFAMILY SSF46785 26 91 9.64E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_10180 8898e45e32b59c0de631d5d267468e8e 236 SMART SM00345 30 88 2.8E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_10180 8898e45e32b59c0de631d5d267468e8e 236 SUPERFAMILY SSF48008 95 222 8.11E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_10180 8898e45e32b59c0de631d5d267468e8e 236 SMART SM00895 99 220 2.2E-18 T 12-10-2018 IPR011711 GntR, C-terminal UA74_10180 8898e45e32b59c0de631d5d267468e8e 236 Gene3D G3DSA:1.10.10.10 23 88 5.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10180 8898e45e32b59c0de631d5d267468e8e 236 Gene3D G3DSA:1.20.120.530 94 229 1.7E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_10180 8898e45e32b59c0de631d5d267468e8e 236 Pfam PF07729 FCD domain 99 219 3.1E-20 T 12-10-2018 IPR011711 GntR, C-terminal UA74_10180 8898e45e32b59c0de631d5d267468e8e 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 85 2.9E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_20655 11925510cadc57425bea38648d6fded7 233 SUPERFAMILY SSF100950 62 230 1.67E-37 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_20655 11925510cadc57425bea38648d6fded7 233 Pfam PF02589 LUD domain 131 230 1.0E-20 T 12-10-2018 IPR003741 LUD domain UA74_20655 11925510cadc57425bea38648d6fded7 233 Gene3D G3DSA:3.40.50.10420 58 231 1.7E-55 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily UA74_11400 4253a05f1cd3c2269eb5aaabb00c4aa7 188 Pfam PF13411 MerR HTH family regulatory protein 30 99 2.7E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_11400 4253a05f1cd3c2269eb5aaabb00c4aa7 188 SUPERFAMILY SSF46955 33 118 3.3E-15 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_11400 4253a05f1cd3c2269eb5aaabb00c4aa7 188 Gene3D G3DSA:1.10.1660.10 29 101 1.2E-13 T 12-10-2018 UA74_11400 4253a05f1cd3c2269eb5aaabb00c4aa7 188 SMART SM00422 30 102 6.1E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_23150 a290e4764822d8ee673118701b04b294 216 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 7 203 3.9E-31 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 UA74_20000 5296f7b9fcd849f3642211de7322627a 406 SUPERFAMILY SSF51004 95 404 1.16E-46 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily UA74_20000 5296f7b9fcd849f3642211de7322627a 406 Gene3D G3DSA:2.130.10.10 67 406 3.7E-102 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_20000 5296f7b9fcd849f3642211de7322627a 406 Pfam PF10282 Lactonase, 7-bladed beta-propeller 76 403 9.3E-96 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller UA74_02760 fb1e937885e2a467194fbaf29a653eee 315 SMART SM00342 226 309 2.6E-29 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_02760 fb1e937885e2a467194fbaf29a653eee 315 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 263 305 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UA74_02760 fb1e937885e2a467194fbaf29a653eee 315 Pfam PF12833 Helix-turn-helix domain 232 310 5.0E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_02760 fb1e937885e2a467194fbaf29a653eee 315 SUPERFAMILY SSF46689 262 311 9.41E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_02760 fb1e937885e2a467194fbaf29a653eee 315 Pfam PF12852 Cupin 4 194 6.5E-54 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain UA74_02760 fb1e937885e2a467194fbaf29a653eee 315 Gene3D G3DSA:1.10.10.60 205 314 5.2E-26 T 12-10-2018 UA74_02760 fb1e937885e2a467194fbaf29a653eee 315 SUPERFAMILY SSF46689 210 259 2.01E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_11180 2857bb757e0f31fdb222280e8425304a 178 SUPERFAMILY SSF55154 4 144 7.85E-20 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 UA74_11180 2857bb757e0f31fdb222280e8425304a 178 Gene3D G3DSA:2.40.320.10 2 163 1.5E-27 T 12-10-2018 UA74_11180 2857bb757e0f31fdb222280e8425304a 178 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 4 131 7.0E-6 T 12-10-2018 UA74_11180 2857bb757e0f31fdb222280e8425304a 178 Pfam PF01928 CYTH domain 3 138 1.4E-9 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 UA74_10485 afbd43095d949932052dfe298fb9306a 358 Pfam PF00248 Aldo/keto reductase family 47 340 1.7E-56 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_10485 afbd43095d949932052dfe298fb9306a 358 Gene3D G3DSA:3.20.20.100 31 355 4.2E-76 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_10485 afbd43095d949932052dfe298fb9306a 358 SUPERFAMILY SSF51430 32 347 2.23E-71 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_07835 3940d512230e630a55f70c66dc6a8f70 111 SUPERFAMILY SSF46955 26 98 2.84E-12 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_07835 3940d512230e630a55f70c66dc6a8f70 111 SMART SM00422 26 94 1.3E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_07835 3940d512230e630a55f70c66dc6a8f70 111 Gene3D G3DSA:1.10.1660.10 21 93 1.7E-15 T 12-10-2018 UA74_07835 3940d512230e630a55f70c66dc6a8f70 111 Pfam PF13411 MerR HTH family regulatory protein 26 89 2.7E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15220 a3acf8d571d6685ff013a5fef2aae56d 266 SUPERFAMILY SSF54593 1 124 1.09E-11 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_15220 a3acf8d571d6685ff013a5fef2aae56d 266 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 145 261 1.0E-5 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_15220 a3acf8d571d6685ff013a5fef2aae56d 266 Gene3D G3DSA:3.10.180.10 3 134 1.6E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_15220 a3acf8d571d6685ff013a5fef2aae56d 266 Gene3D G3DSA:3.10.180.10 142 266 3.6E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_15220 a3acf8d571d6685ff013a5fef2aae56d 266 SUPERFAMILY SSF54593 145 265 7.56E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_10620 0eced17595081e6ecaa3b6f5cbfab4f4 328 Gene3D G3DSA:3.40.50.300 63 320 1.7E-64 T 12-10-2018 UA74_10620 0eced17595081e6ecaa3b6f5cbfab4f4 328 Pfam PF00005 ABC transporter 90 250 2.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_10620 0eced17595081e6ecaa3b6f5cbfab4f4 328 SMART SM00382 99 299 1.9E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_10620 0eced17595081e6ecaa3b6f5cbfab4f4 328 SUPERFAMILY SSF52540 73 321 4.17E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10620 0eced17595081e6ecaa3b6f5cbfab4f4 328 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 300 321 9.3E-11 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal UA74_16850 4dd6ad5a807ca976ecfefb50b6f20e3c 147 SUPERFAMILY SSF46785 12 140 2.25E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_16850 4dd6ad5a807ca976ecfefb50b6f20e3c 147 Pfam PF01047 MarR family 33 91 2.8E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_16850 4dd6ad5a807ca976ecfefb50b6f20e3c 147 Gene3D G3DSA:1.10.10.10 5 138 6.0E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16850 4dd6ad5a807ca976ecfefb50b6f20e3c 147 SMART SM00347 26 125 2.0E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_08750 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01270 Histone deacetylase superfamily signature 164 179 1.0E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_08750 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01270 Histone deacetylase superfamily signature 250 260 1.0E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_08750 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01270 Histone deacetylase superfamily signature 131 154 1.0E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_08750 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01272 Acetoin utilisation ACUC protein signature 108 121 7.2E-5 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UA74_08750 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 7.2E-5 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UA74_08750 06c54bd9c1a632f55649f6c5c0602f2a 403 PRINTS PR01272 Acetoin utilisation ACUC protein signature 87 101 7.2E-5 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UA74_08750 06c54bd9c1a632f55649f6c5c0602f2a 403 Gene3D G3DSA:3.40.800.20 2 356 6.2E-103 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_08750 06c54bd9c1a632f55649f6c5c0602f2a 403 SUPERFAMILY SSF52768 4 338 3.12E-100 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily UA74_08750 06c54bd9c1a632f55649f6c5c0602f2a 403 Pfam PF00850 Histone deacetylase domain 21 321 6.7E-75 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UA74_27305 a52fef3743bd976931ab48556da9be6a 142 Pfam PF00293 NUDIX domain 18 125 8.4E-18 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_27305 a52fef3743bd976931ab48556da9be6a 142 PRINTS PR00502 NUDIX hydrolase family signature 46 60 3.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_27305 a52fef3743bd976931ab48556da9be6a 142 PRINTS PR00502 NUDIX hydrolase family signature 60 75 3.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_27305 a52fef3743bd976931ab48556da9be6a 142 Gene3D G3DSA:3.90.79.10 17 139 2.1E-28 T 12-10-2018 UA74_27305 a52fef3743bd976931ab48556da9be6a 142 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_27305 a52fef3743bd976931ab48556da9be6a 142 SUPERFAMILY SSF55811 16 130 3.52E-28 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_26590 0eb21d983b9f4696c3f383d6247e2d77 158 Gene3D G3DSA:3.30.2010.20 33 156 2.9E-12 T 12-10-2018 IPR038555 Zincin-like metallopeptidase superfamily UA74_26590 0eb21d983b9f4696c3f383d6247e2d77 158 SUPERFAMILY SSF55486 35 155 5.86E-24 T 12-10-2018 UA74_26590 0eb21d983b9f4696c3f383d6247e2d77 158 Pfam PF06262 Zincin-like metallopeptidase 61 153 3.2E-10 T 12-10-2018 IPR010428 Zincin-like metallopeptidase UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 305 314 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 Pfam PF00067 Cytochrome P450 234 333 1.8E-17 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 Gene3D G3DSA:1.10.630.10 1 366 4.9E-128 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 SUPERFAMILY SSF48264 1 365 1.24E-87 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00359 B-class P450 signature 253 280 2.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00359 B-class P450 signature 50 61 2.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00359 B-class P450 signature 235 246 2.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00359 B-class P450 signature 312 323 2.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00359 B-class P450 signature 303 312 2.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00359 B-class P450 signature 99 115 2.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00359 B-class P450 signature 116 131 2.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00359 B-class P450 signature 153 175 2.8E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00385 P450 superfamily signature 235 246 1.7E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00385 P450 superfamily signature 303 312 1.7E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00385 P450 superfamily signature 200 217 1.7E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20320 6d3b2b4d6e32d696eb6f1b30f2dda6b6 369 PRINTS PR00385 P450 superfamily signature 312 323 1.7E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_13245 2fa71b9b57e74a0d1db021528b6a45e0 741 Gene3D G3DSA:3.40.50.300 466 736 5.4E-62 T 12-10-2018 UA74_13245 2fa71b9b57e74a0d1db021528b6a45e0 741 SMART SM00382 525 711 2.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13245 2fa71b9b57e74a0d1db021528b6a45e0 741 SUPERFAMILY SSF90123 161 469 8.63E-54 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13245 2fa71b9b57e74a0d1db021528b6a45e0 741 Pfam PF00664 ABC transporter transmembrane region 166 434 4.6E-32 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_13245 2fa71b9b57e74a0d1db021528b6a45e0 741 Gene3D G3DSA:1.20.1560.10 122 465 6.3E-54 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_13245 2fa71b9b57e74a0d1db021528b6a45e0 741 SUPERFAMILY SSF52540 508 734 2.33E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13245 2fa71b9b57e74a0d1db021528b6a45e0 741 Pfam PF00005 ABC transporter 516 664 4.0E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_07025 3368a318b14fc17b18dc2efce39559ae 388 Pfam PF00953 Glycosyl transferase family 4 94 259 7.2E-30 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 UA74_07170 4682a672374e3c541fb876f437374ff7 249 Gene3D G3DSA:3.40.50.1820 14 223 2.3E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07170 4682a672374e3c541fb876f437374ff7 249 SUPERFAMILY SSF53474 14 220 1.26E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_12185 fc254bc89d5e30d4154eaa5b7603032c 216 Pfam PF00156 Phosphoribosyl transferase domain 23 162 2.0E-18 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_12185 fc254bc89d5e30d4154eaa5b7603032c 216 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 15 192 35.605 T 12-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 UA74_12185 fc254bc89d5e30d4154eaa5b7603032c 216 Gene3D G3DSA:3.40.50.2020 5 198 2.2E-61 T 12-10-2018 UA74_12185 fc254bc89d5e30d4154eaa5b7603032c 216 SUPERFAMILY SSF53271 21 186 8.15E-40 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_10435 5afacd853fa62bf3f4f08de0d4b8b2a9 316 Gene3D G3DSA:3.40.50.2000 148 313 2.1E-40 T 12-10-2018 UA74_10435 5afacd853fa62bf3f4f08de0d4b8b2a9 316 Gene3D G3DSA:3.40.50.2000 6 97 6.5E-7 T 12-10-2018 UA74_10435 5afacd853fa62bf3f4f08de0d4b8b2a9 316 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 154 274 7.2E-28 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 UA74_10435 5afacd853fa62bf3f4f08de0d4b8b2a9 316 SUPERFAMILY SSF53756 6 311 8.63E-57 T 12-10-2018 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 SMART SM00530 18 74 2.9E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 SMART SM00028 724 757 7.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 SMART SM00028 641 674 230.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 SMART SM00028 681 714 89.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 Pfam PF13560 Helix-turn-helix domain 15 77 6.1E-11 T 12-10-2018 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 SUPERFAMILY SSF47413 14 72 3.75E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 SUPERFAMILY SSF52540 147 414 7.46E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 SUPERFAMILY SSF48452 585 716 4.05E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 Gene3D G3DSA:1.10.260.40 11 92 1.2E-12 T 12-10-2018 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 PRINTS PR00364 Disease resistance protein signature 185 200 3.1E-11 T 12-10-2018 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 PRINTS PR00364 Disease resistance protein signature 347 361 3.1E-11 T 12-10-2018 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 PRINTS PR00364 Disease resistance protein signature 262 276 3.1E-11 T 12-10-2018 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 SUPERFAMILY SSF48452 686 787 1.01E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 Pfam PF13424 Tetratricopeptide repeat 683 754 4.3E-8 T 12-10-2018 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 Pfam PF00931 NB-ARC domain 180 418 2.7E-15 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 Gene3D G3DSA:3.40.50.300 144 307 1.1E-27 T 12-10-2018 UA74_20865 2268240c4116d9c464e7146c66d74e5c 872 Gene3D G3DSA:1.25.40.10 533 819 6.0E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_22480 10ff8cba1245e30914651a76b0d83cf3 503 SUPERFAMILY SSF53850 33 492 3.04E-119 T 12-10-2018 UA74_22480 10ff8cba1245e30914651a76b0d83cf3 503 Gene3D G3DSA:3.90.76.10 50 193 1.6E-109 T 12-10-2018 UA74_22480 10ff8cba1245e30914651a76b0d83cf3 503 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 410 9.2E-84 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_22480 10ff8cba1245e30914651a76b0d83cf3 503 PIRSF PIRSF002741 1 497 1.2E-92 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_22480 10ff8cba1245e30914651a76b0d83cf3 503 Gene3D G3DSA:3.10.105.10 274 477 1.6E-109 T 12-10-2018 UA74_22480 10ff8cba1245e30914651a76b0d83cf3 503 Gene3D G3DSA:3.40.190.10 194 485 1.6E-109 T 12-10-2018 UA74_07555 102f46090c23bac416aa978c4908c35a 354 SMART SM00248 105 134 150.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 SMART SM00248 217 246 1.4E-4 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 SMART SM00248 178 207 120.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 SMART SM00248 37 66 0.057 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 SMART SM00248 286 315 6.5E-4 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 SMART SM00248 251 281 1.3 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 SMART SM00248 71 100 0.03 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 SUPERFAMILY SSF48403 9 328 4.57E-46 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily UA74_07555 102f46090c23bac416aa978c4908c35a 354 Pfam PF00023 Ankyrin repeat 38 67 0.0028 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 PRINTS PR01415 Ankyrin repeat signature 233 247 1.9E-6 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 PRINTS PR01415 Ankyrin repeat signature 38 53 1.9E-6 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_07555 102f46090c23bac416aa978c4908c35a 354 Gene3D G3DSA:1.25.40.20 2 167 1.6E-33 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily UA74_07555 102f46090c23bac416aa978c4908c35a 354 Pfam PF12796 Ankyrin repeats (3 copies) 72 131 2.1E-7 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain UA74_07555 102f46090c23bac416aa978c4908c35a 354 Gene3D G3DSA:1.25.40.20 168 343 1.2E-36 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily UA74_07555 102f46090c23bac416aa978c4908c35a 354 Pfam PF13637 Ankyrin repeats (many copies) 219 271 1.5E-10 T 12-10-2018 UA74_22730 02500818b7c86e397f461bfabd97bc37 213 Pfam PF01081 KDPG and KHG aldolase 11 201 8.2E-41 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_22730 02500818b7c86e397f461bfabd97bc37 213 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 209 6.5E-50 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_22730 02500818b7c86e397f461bfabd97bc37 213 Gene3D G3DSA:3.20.20.70 3 213 5.9E-61 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_22730 02500818b7c86e397f461bfabd97bc37 213 SUPERFAMILY SSF51569 9 210 2.75E-51 T 12-10-2018 UA74_00740 9be8b79d87067d5fce824a4fa0d8d57f 429 SUPERFAMILY SSF56219 63 424 4.48E-22 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_00740 9be8b79d87067d5fce824a4fa0d8d57f 429 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 87 417 7.7E-30 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase UA74_00740 9be8b79d87067d5fce824a4fa0d8d57f 429 Gene3D G3DSA:3.60.10.10 62 427 5.3E-23 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 SUPERFAMILY SSF49299 714 801 1.57E-17 T 12-10-2018 IPR035986 PKD domain superfamily UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 Pfam PF00801 PKD domain 721 786 4.2E-9 T 12-10-2018 IPR000601 PKD domain UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 SMART SM00606 905 1035 6.8E-23 T 12-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 SMART SM00089 716 799 9.1E-16 T 12-10-2018 IPR022409 PKD/Chitinase domain UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 SUPERFAMILY SSF52317 36 264 1.37E-33 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 Gene3D G3DSA:2.120.10.30 267 709 1.9E-66 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 Pfam PF03422 Carbohydrate binding module (family 6) 913 1034 1.8E-24 T 12-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 SUPERFAMILY SSF50952 271 693 4.97E-18 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 SUPERFAMILY SSF49785 909 1034 2.55E-21 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 Gene3D G3DSA:2.60.40.10 710 800 4.8E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 Gene3D G3DSA:2.60.40.10 1140 1228 6.9E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 Pfam PF06283 Trehalose utilisation 38 258 1.8E-57 T 12-10-2018 IPR029010 ThuA-like domain UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 Pfam PF07995 Glucose / Sorbosone dehydrogenase 284 546 8.2E-33 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 Gene3D G3DSA:2.60.120.260 908 1035 9.3E-29 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_20665 579bbbbcfea93296fb709b2d66caed2c 1398 Gene3D G3DSA:3.40.50.880 24 266 2.9E-70 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_15215 d3ecd08a8919bb987acdb8745238191d 139 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 135 5.2E-15 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_15215 d3ecd08a8919bb987acdb8745238191d 139 SUPERFAMILY SSF54593 8 137 3.76E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_15215 d3ecd08a8919bb987acdb8745238191d 139 Gene3D G3DSA:3.10.180.10 5 139 8.9E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_12005 4dca328233630aa453c5ea519866a2c6 477 Gene3D G3DSA:3.40.50.300 40 200 3.8E-38 T 12-10-2018 UA74_12005 4dca328233630aa453c5ea519866a2c6 477 Pfam PF16193 AAA C-terminal domain 223 299 6.6E-27 T 12-10-2018 IPR032423 AAA C-terminal domain UA74_12005 4dca328233630aa453c5ea519866a2c6 477 SUPERFAMILY SSF52540 50 268 1.31E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12005 4dca328233630aa453c5ea519866a2c6 477 Gene3D G3DSA:1.10.8.60 201 271 6.4E-11 T 12-10-2018 UA74_12005 4dca328233630aa453c5ea519866a2c6 477 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 88 192 1.3E-15 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_12005 4dca328233630aa453c5ea519866a2c6 477 Gene3D G3DSA:1.20.272.10 273 377 1.4E-46 T 12-10-2018 UA74_12005 4dca328233630aa453c5ea519866a2c6 477 Pfam PF12002 MgsA AAA+ ATPase C terminal 300 465 3.3E-70 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal UA74_12005 4dca328233630aa453c5ea519866a2c6 477 SUPERFAMILY SSF48019 285 469 6.23E-73 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 UA74_12005 4dca328233630aa453c5ea519866a2c6 477 SMART SM00382 84 220 1.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_12005 4dca328233630aa453c5ea519866a2c6 477 Gene3D G3DSA:1.10.3710.10 378 476 1.4E-24 T 12-10-2018 UA74_14875 e0b97f30851b5ce9bc33554b436c7bce 209 Gene3D G3DSA:2.30.110.10 34 159 3.9E-30 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_14875 e0b97f30851b5ce9bc33554b436c7bce 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 127 2.1E-16 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_14875 e0b97f30851b5ce9bc33554b436c7bce 209 SUPERFAMILY SSF50475 39 154 1.43E-21 T 12-10-2018 UA74_14875 e0b97f30851b5ce9bc33554b436c7bce 209 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 14 208 5.5E-73 T 12-10-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent UA74_18100 370b2c9d4c152890d05ee5011231691a 321 Pfam PF01794 Ferric reductase like transmembrane component 88 212 1.4E-12 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.7E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 Gene3D G3DSA:3.40.50.720 14 290 6.9E-80 T 12-10-2018 UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 16 197 0.0023 T 12-10-2018 UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 9.5E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 9.5E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 9.5E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 Pfam PF00106 short chain dehydrogenase 17 201 6.5E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07540 eff3802c6be0b1d29536d64be1bca98d 290 SUPERFAMILY SSF51735 15 249 3.47E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_01635 8486602e47f41146635b88aab1c79477 282 SUPERFAMILY SSF52467 6 276 2.15E-62 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UA74_01635 8486602e47f41146635b88aab1c79477 282 Gene3D G3DSA:3.40.50.1220 17 270 1.1E-39 T 12-10-2018 UA74_01635 8486602e47f41146635b88aab1c79477 282 Pfam PF02146 Sir2 family 25 189 5.5E-18 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 UA74_01635 8486602e47f41146635b88aab1c79477 282 Gene3D G3DSA:3.30.1600.10 34 189 1.1E-39 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily UA74_20755 bf22f92c744f4ca14a804a1064ee56ac 590 SUPERFAMILY SSF69279 29 183 2.38E-19 T 12-10-2018 UA74_20755 bf22f92c744f4ca14a804a1064ee56ac 590 Gene3D G3DSA:2.40.50.230 376 462 1.8E-9 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily UA74_20755 bf22f92c744f4ca14a804a1064ee56ac 590 SUPERFAMILY SSF69255 382 458 4.71E-12 T 12-10-2018 UA74_20755 bf22f92c744f4ca14a804a1064ee56ac 590 SUPERFAMILY SSF69349 450 579 8.63E-5 T 12-10-2018 UA74_20755 bf22f92c744f4ca14a804a1064ee56ac 590 Pfam PF05954 Phage late control gene D protein (GPD) 40 348 1.5E-16 T 12-10-2018 UA74_20130 f0759db2b0839b18a3e53ccbb160f5bb 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 290 1.2E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_20130 f0759db2b0839b18a3e53ccbb160f5bb 291 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 60 3.0E-8 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_20130 f0759db2b0839b18a3e53ccbb160f5bb 291 SUPERFAMILY SSF161098 85 274 1.96E-28 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20130 f0759db2b0839b18a3e53ccbb160f5bb 291 Gene3D G3DSA:1.10.3720.10 80 286 9.8E-23 T 12-10-2018 IPR035906 MetI-like superfamily UA74_21840 0824f346371e50de383889ca7a96530b 101 SUPERFAMILY SSF47336 13 99 4.89E-9 T 12-10-2018 IPR036736 ACP-like superfamily UA74_21840 0824f346371e50de383889ca7a96530b 101 Gene3D G3DSA:1.10.1200.10 5 95 7.4E-9 T 12-10-2018 IPR036736 ACP-like superfamily UA74_09825 ea67d69c4f3124d3f5acaf5bbabefee8 209 Gene3D G3DSA:3.90.79.10 1 117 1.2E-26 T 12-10-2018 UA74_09825 ea67d69c4f3124d3f5acaf5bbabefee8 209 SUPERFAMILY SSF46785 120 191 2.64E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_09825 ea67d69c4f3124d3f5acaf5bbabefee8 209 Pfam PF00293 NUDIX domain 1 101 2.7E-9 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_09825 ea67d69c4f3124d3f5acaf5bbabefee8 209 Gene3D G3DSA:1.10.10.10 118 196 4.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_09825 ea67d69c4f3124d3f5acaf5bbabefee8 209 SUPERFAMILY SSF55811 1 116 3.11E-26 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_08740 812b56487345f89bc79568e25628e665 293 SUPERFAMILY SSF52821 12 155 3.27E-38 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_08740 812b56487345f89bc79568e25628e665 293 Gene3D G3DSA:3.40.250.10 3 157 4.8E-47 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_08740 812b56487345f89bc79568e25628e665 293 SUPERFAMILY SSF52821 174 287 8.25E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_08740 812b56487345f89bc79568e25628e665 293 ProSitePatterns PS00683 Rhodanese C-terminal signature. 268 278 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 UA74_08740 812b56487345f89bc79568e25628e665 293 Pfam PF00581 Rhodanese-like domain 173 279 2.2E-9 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_08740 812b56487345f89bc79568e25628e665 293 Pfam PF00581 Rhodanese-like domain 17 136 3.0E-17 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_08740 812b56487345f89bc79568e25628e665 293 Gene3D G3DSA:3.40.250.10 163 286 2.6E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_08740 812b56487345f89bc79568e25628e665 293 SMART SM00450 161 284 1.3E-14 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_08740 812b56487345f89bc79568e25628e665 293 SMART SM00450 16 140 9.1E-23 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_13930 f9c16671aa5002da608a257153969105 281 SUPERFAMILY SSF63992 7 273 4.32E-83 T 12-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily UA74_13930 f9c16671aa5002da608a257153969105 281 PIRSF PIRSF015853 7 278 5.2E-91 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase UA74_13930 f9c16671aa5002da608a257153969105 281 Pfam PF04951 D-aminopeptidase 7 266 1.8E-92 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase UA74_13930 f9c16671aa5002da608a257153969105 281 Gene3D G3DSA:3.40.50.10780 7 219 1.2E-83 T 12-10-2018 IPR027476 D-aminopeptidase, N-terminal UA74_13930 f9c16671aa5002da608a257153969105 281 Gene3D G3DSA:3.30.1360.130 124 264 1.2E-83 T 12-10-2018 UA74_17695 2c61909fa918ecb1224d14a3566fcde6 210 Pfam PF08798 CRISPR associated protein 3 206 1.9E-39 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 UA74_17695 2c61909fa918ecb1224d14a3566fcde6 210 SUPERFAMILY SSF117987 3 79 7.85E-11 T 12-10-2018 UA74_17695 2c61909fa918ecb1224d14a3566fcde6 210 SMART SM01101 2 206 1.7E-39 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 UA74_17695 2c61909fa918ecb1224d14a3566fcde6 210 Gene3D G3DSA:3.30.70.1210 93 207 1.4E-19 T 12-10-2018 UA74_17695 2c61909fa918ecb1224d14a3566fcde6 210 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 24 206 1.8E-13 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 UA74_17695 2c61909fa918ecb1224d14a3566fcde6 210 SUPERFAMILY SSF117987 94 206 4.97E-20 T 12-10-2018 UA74_17695 2c61909fa918ecb1224d14a3566fcde6 210 Gene3D G3DSA:3.30.70.1200 1 89 1.0E-13 T 12-10-2018 UA74_22985 dbdc2eaad389833ca7b853ad33303bc7 401 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 76 222 1.4E-26 T 12-10-2018 UA74_22985 dbdc2eaad389833ca7b853ad33303bc7 401 SUPERFAMILY SSF53335 23 224 3.04E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_22985 dbdc2eaad389833ca7b853ad33303bc7 401 Gene3D G3DSA:3.40.50.150 17 257 6.5E-54 T 12-10-2018 UA74_03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 Gene3D G3DSA:3.50.50.100 1 365 2.3E-67 T 12-10-2018 UA74_03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 3.6E-10 T 12-10-2018 UA74_03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 3.6E-10 T 12-10-2018 UA74_03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.6E-10 T 12-10-2018 UA74_03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.6E-10 T 12-10-2018 UA74_03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 SUPERFAMILY SSF51905 2 302 6.74E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_03545 9a7230e8b5f5ec9d015834d9dddd92e5 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 294 2.7E-36 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_17265 3dca155f5a80c03f4f22597b340935d5 279 SUPERFAMILY SSF51735 5 216 9.02E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17265 3dca155f5a80c03f4f22597b340935d5 279 Gene3D G3DSA:3.40.50.720 7 245 4.0E-24 T 12-10-2018 UA74_17265 3dca155f5a80c03f4f22597b340935d5 279 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 178 8.3E-13 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_09175 bcedfb937e6ebbdf274744295de8d093 424 SUPERFAMILY SSF56112 196 388 1.94E-15 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_09175 bcedfb937e6ebbdf274744295de8d093 424 Gene3D G3DSA:1.10.510.10 314 418 2.8E-16 T 12-10-2018 UA74_09175 bcedfb937e6ebbdf274744295de8d093 424 Pfam PF01163 RIO1 family 246 401 1.1E-30 T 12-10-2018 UA74_09175 bcedfb937e6ebbdf274744295de8d093 424 SMART SM00090 187 416 1.8E-8 T 12-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 UA74_02670 12a718947081a113aaf31803fe2e4caa 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 216 4.6E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_02670 12a718947081a113aaf31803fe2e4caa 224 Pfam PF00072 Response regulator receiver domain 3 112 1.7E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_02670 12a718947081a113aaf31803fe2e4caa 224 SMART SM00448 1 112 7.0E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_02670 12a718947081a113aaf31803fe2e4caa 224 Gene3D G3DSA:1.10.10.10 125 223 2.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02670 12a718947081a113aaf31803fe2e4caa 224 Gene3D G3DSA:3.40.50.2300 1 124 6.6E-32 T 12-10-2018 UA74_02670 12a718947081a113aaf31803fe2e4caa 224 SMART SM00862 145 217 3.0E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_02670 12a718947081a113aaf31803fe2e4caa 224 SUPERFAMILY SSF52172 1 175 2.26E-33 T 12-10-2018 IPR011006 CheY-like superfamily UA74_02765 385d125b88aa0f588bd406ff5c549ba7 291 Gene3D G3DSA:3.40.50.720 24 269 4.4E-46 T 12-10-2018 UA74_02765 385d125b88aa0f588bd406ff5c549ba7 291 Pfam PF13460 NAD(P)H-binding 27 186 1.1E-8 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_02765 385d125b88aa0f588bd406ff5c549ba7 291 Gene3D G3DSA:3.90.25.10 138 271 4.4E-46 T 12-10-2018 UA74_02765 385d125b88aa0f588bd406ff5c549ba7 291 SUPERFAMILY SSF51735 20 254 6.25E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_05620 4c3b5e25d374671a033493d24563989f 268 SUPERFAMILY SSF46785 16 85 2.59E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_05620 4c3b5e25d374671a033493d24563989f 268 Gene3D G3DSA:1.10.10.10 2 76 2.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_05620 4c3b5e25d374671a033493d24563989f 268 SMART SM00346 16 105 1.5E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_05620 4c3b5e25d374671a033493d24563989f 268 Gene3D G3DSA:3.30.450.40 82 266 4.1E-37 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_05620 4c3b5e25d374671a033493d24563989f 268 SUPERFAMILY SSF55781 93 260 1.83E-27 T 12-10-2018 UA74_05620 4c3b5e25d374671a033493d24563989f 268 Pfam PF09339 IclR helix-turn-helix domain 18 66 6.1E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_05620 4c3b5e25d374671a033493d24563989f 268 Pfam PF01614 Bacterial transcriptional regulator 134 260 3.6E-8 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_20635 48a8c99ecbe561b3e539ebebde5d4411 293 Pfam PF01936 NYN domain 3 165 1.1E-12 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type UA74_20635 48a8c99ecbe561b3e539ebebde5d4411 293 Gene3D G3DSA:3.40.50.1010 39 172 4.5E-7 T 12-10-2018 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Gene3D G3DSA:3.30.870.10 568 748 5.7E-55 T 12-10-2018 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Hamap MF_00347 Polyphosphate kinase [ppk]. 60 747 28.339 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Gene3D G3DSA:3.30.1840.10 55 377 5.4E-115 T 12-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 62 741 4.0E-244 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 PIRSF PIRSF015589 43 749 9.1E-266 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Pfam PF13089 Polyphosphate kinase N-terminal domain 63 166 9.3E-35 T 12-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Pfam PF13090 Polyphosphate kinase C-terminal domain 397 741 6.3E-145 T 12-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 SUPERFAMILY SSF143724 167 376 3.73E-66 T 12-10-2018 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 SUPERFAMILY SSF140356 60 163 3.66E-35 T 12-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 SUPERFAMILY SSF56024 392 565 1.26E-56 T 12-10-2018 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Pfam PF02503 Polyphosphate kinase middle domain 179 386 9.3E-70 T 12-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 SUPERFAMILY SSF56024 569 743 2.24E-58 T 12-10-2018 UA74_25825 c64bc9edb14e84e4a7fe1c25d76fd0ba 749 Gene3D G3DSA:3.30.870.10 385 567 6.7E-74 T 12-10-2018 UA74_07855 0f2a785b4586a05fdaa0c40023401048 141 SUPERFAMILY SSF50249 4 129 2.95E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_07855 0f2a785b4586a05fdaa0c40023401048 141 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 129 4.2E-17 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UA74_07855 0f2a785b4586a05fdaa0c40023401048 141 PIRSF PIRSF002070 1 138 1.4E-16 T 12-10-2018 UA74_07855 0f2a785b4586a05fdaa0c40023401048 141 Gene3D G3DSA:2.40.50.140 1 117 2.7E-36 T 12-10-2018 UA74_07855 0f2a785b4586a05fdaa0c40023401048 141 Pfam PF00436 Single-strand binding protein family 5 104 2.2E-16 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 UA74_08165 e706c63f1ab563ca1e7569f489a151c4 189 PIRSF PIRSF018427 1 188 9.9E-47 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_08165 e706c63f1ab563ca1e7569f489a151c4 189 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 15 189 27.477 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_08165 e706c63f1ab563ca1e7569f489a151c4 189 Pfam PF00293 NUDIX domain 42 175 9.6E-24 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_08165 e706c63f1ab563ca1e7569f489a151c4 189 SUPERFAMILY SSF55811 17 179 1.02E-38 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_08165 e706c63f1ab563ca1e7569f489a151c4 189 Gene3D G3DSA:3.90.79.10 1 186 9.9E-47 T 12-10-2018 UA74_08165 e706c63f1ab563ca1e7569f489a151c4 189 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 19 177 2.2E-34 T 12-10-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 UA74_01915 35d61261fa982b54cb0ec578b823813b 258 Pfam PF05690 Thiazole biosynthesis protein ThiG 7 249 2.9E-102 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 UA74_01915 35d61261fa982b54cb0ec578b823813b 258 Hamap MF_00443 Thiazole synthase [thiG]. 4 256 41.016 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 UA74_01915 35d61261fa982b54cb0ec578b823813b 258 SUPERFAMILY SSF110399 3 241 2.75E-78 T 12-10-2018 UA74_01915 35d61261fa982b54cb0ec578b823813b 258 Gene3D G3DSA:3.20.20.70 1 253 8.1E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_02025 ed5fe84f9b3f3e33e201311fa2558633 132 TIGRFAM TIGR00494 crcB: protein CrcB 12 123 2.1E-23 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_02025 ed5fe84f9b3f3e33e201311fa2558633 132 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 10 126 17.223 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_02025 ed5fe84f9b3f3e33e201311fa2558633 132 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 12 121 2.7E-20 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_27985 e4f331b6148d7694040c0b24d266352f 503 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 438 448 - T 12-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site UA74_27985 e4f331b6148d7694040c0b24d266352f 503 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 253 479 3.1E-42 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_27985 e4f331b6148d7694040c0b24d266352f 503 Gene3D G3DSA:3.40.50.10260 3 232 7.3E-48 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 UA74_27985 e4f331b6148d7694040c0b24d266352f 503 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 227 19.066 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 UA74_27985 e4f331b6148d7694040c0b24d266352f 503 Gene3D G3DSA:3.40.1190.20 237 503 8.0E-70 T 12-10-2018 IPR029056 Ribokinase-like UA74_27985 e4f331b6148d7694040c0b24d266352f 503 Pfam PF01256 Carbohydrate kinase 262 481 2.1E-50 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_27985 e4f331b6148d7694040c0b24d266352f 503 Pfam PF03853 YjeF-related protein N-terminus 25 206 9.3E-35 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 UA74_27985 e4f331b6148d7694040c0b24d266352f 503 SUPERFAMILY SSF53613 238 496 3.27E-51 T 12-10-2018 IPR029056 Ribokinase-like UA74_27985 e4f331b6148d7694040c0b24d266352f 503 PIRSF PIRSF017184 3 500 1.2E-90 T 12-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 UA74_27985 e4f331b6148d7694040c0b24d266352f 503 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 239 500 18.545 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_27985 e4f331b6148d7694040c0b24d266352f 503 SUPERFAMILY SSF64153 4 260 3.66E-44 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 UA74_23920 c2df99f9a64fc6b22cb822d0ecbe220d 475 SUPERFAMILY SSF53098 42 205 1.57E-44 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_23920 c2df99f9a64fc6b22cb822d0ecbe220d 475 SUPERFAMILY SSF52113 388 457 1.44E-7 T 12-10-2018 IPR036420 BRCT domain superfamily UA74_23920 c2df99f9a64fc6b22cb822d0ecbe220d 475 Pfam PF00929 Exonuclease 45 198 8.5E-21 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_23920 c2df99f9a64fc6b22cb822d0ecbe220d 475 SMART SM00479 42 208 2.0E-27 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_23920 c2df99f9a64fc6b22cb822d0ecbe220d 475 Gene3D G3DSA:3.40.50.10190 386 466 3.9E-13 T 12-10-2018 IPR036420 BRCT domain superfamily UA74_23920 c2df99f9a64fc6b22cb822d0ecbe220d 475 Gene3D G3DSA:3.30.420.10 39 205 1.4E-42 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_02530 a677a95147acf84783005c707a500920 169 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 16 168 2.7E-55 T 12-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit UA74_02530 a677a95147acf84783005c707a500920 169 Pfam PF01883 Iron-sulfur cluster assembly protein 7 71 2.0E-13 T 12-10-2018 IPR002744 MIP18 family-like UA74_02530 a677a95147acf84783005c707a500920 169 Gene3D G3DSA:3.30.300.130 2 101 1.0E-22 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UA74_02530 a677a95147acf84783005c707a500920 169 SUPERFAMILY SSF117916 2 98 3.6E-23 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UA74_10570 10b1188b94ab7cdf063dec694280b713 702 SUPERFAMILY SSF81345 22 352 8.24E-58 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_10570 10b1188b94ab7cdf063dec694280b713 702 Pfam PF01032 FecCD transport family 39 352 9.8E-69 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_10570 10b1188b94ab7cdf063dec694280b713 702 Pfam PF01032 FecCD transport family 392 696 3.6E-83 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_10570 10b1188b94ab7cdf063dec694280b713 702 SUPERFAMILY SSF81345 377 696 2.88E-72 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_10570 10b1188b94ab7cdf063dec694280b713 702 Gene3D G3DSA:1.10.3470.10 25 358 2.3E-74 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_10570 10b1188b94ab7cdf063dec694280b713 702 Gene3D G3DSA:1.10.3470.10 376 702 9.0E-88 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_16970 7a266523c2a428bd6a80ba8b2d99acce 782 Gene3D G3DSA:3.40.50.12780 23 369 2.2E-53 T 12-10-2018 UA74_16970 7a266523c2a428bd6a80ba8b2d99acce 782 Gene3D G3DSA:1.10.10.10 480 547 2.6E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16970 7a266523c2a428bd6a80ba8b2d99acce 782 SUPERFAMILY SSF53335 615 755 3.77E-5 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_16970 7a266523c2a428bd6a80ba8b2d99acce 782 Gene3D G3DSA:3.30.300.30 372 479 1.4E-13 T 12-10-2018 UA74_16970 7a266523c2a428bd6a80ba8b2d99acce 782 Pfam PF13193 AMP-binding enzyme C-terminal domain 385 467 1.2E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_16970 7a266523c2a428bd6a80ba8b2d99acce 782 Pfam PF00501 AMP-binding enzyme 41 342 1.3E-40 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_16970 7a266523c2a428bd6a80ba8b2d99acce 782 SUPERFAMILY SSF56801 24 479 2.09E-79 T 12-10-2018 UA74_16970 7a266523c2a428bd6a80ba8b2d99acce 782 Gene3D G3DSA:3.40.50.150 607 781 7.0E-6 T 12-10-2018 UA74_16970 7a266523c2a428bd6a80ba8b2d99acce 782 ProSitePatterns PS00455 Putative AMP-binding domain signature. 150 161 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_17290 5f58b22024104e84537cfd3f8cf7715a 148 SUPERFAMILY SSF51182 17 142 7.18E-38 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_17290 5f58b22024104e84537cfd3f8cf7715a 148 Pfam PF05523 WxcM-like, C-terminal 17 143 8.0E-48 T 12-10-2018 IPR008894 WxcM-like, C-terminal KEGG: 00523+5.3.2.3|MetaCyc: PWY-6953|MetaCyc: PWY-7688 UA74_17290 5f58b22024104e84537cfd3f8cf7715a 148 Gene3D G3DSA:2.60.120.10 1 145 2.6E-46 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 Gene3D G3DSA:3.30.300.20 384 465 7.2E-25 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 384 462 3.5E-25 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 SMART SM00382 32 168 0.95 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 SMART SM00382 207 447 0.61 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 209 344 4.9E-22 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 35 160 3.9E-20 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 Gene3D G3DSA:3.40.50.300 208 380 6.0E-41 T 12-10-2018 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 PIRSF PIRSF006485 33 470 6.0E-157 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 231 4.5E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 260 275 4.5E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 Pfam PF01926 50S ribosome-binding GTPase 210 328 4.2E-20 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 Pfam PF01926 50S ribosome-binding GTPase 36 150 9.7E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 Gene3D G3DSA:3.40.50.300 32 191 2.0E-41 T 12-10-2018 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 34 462 3.9E-151 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 Hamap MF_00195 GTPase Der [der]. 33 465 34.585 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 SUPERFAMILY SSF52540 35 197 1.36E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10075 67887cba4a1c96f7c87dd7c3c3c41830 472 SUPERFAMILY SSF52540 168 466 5.06E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07080 d12fbceb392a944cdfd710be2f3b4773 121 SUPERFAMILY SSF51344 4 84 3.79E-20 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07080 d12fbceb392a944cdfd710be2f3b4773 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 84 5.0E-22 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07080 d12fbceb392a944cdfd710be2f3b4773 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 109 5.9E-22 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07080 d12fbceb392a944cdfd710be2f3b4773 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 116 17.306 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07080 d12fbceb392a944cdfd710be2f3b4773 121 Gene3D G3DSA:2.60.15.10 2 121 2.4E-26 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07080 d12fbceb392a944cdfd710be2f3b4773 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 84 7.3E-25 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_09830 af16c20c54b70fa21fb0d0baee1a27d6 347 Gene3D G3DSA:3.40.50.10800 34 321 2.7E-109 T 12-10-2018 UA74_09830 af16c20c54b70fa21fb0d0baee1a27d6 347 Gene3D G3DSA:3.40.50.10800 199 296 2.7E-109 T 12-10-2018 UA74_09830 af16c20c54b70fa21fb0d0baee1a27d6 347 Gene3D G3DSA:3.40.50.10800 114 339 2.7E-109 T 12-10-2018 UA74_09830 af16c20c54b70fa21fb0d0baee1a27d6 347 Pfam PF02445 Quinolinate synthetase A protein 35 339 1.6E-110 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 UA74_09830 af16c20c54b70fa21fb0d0baee1a27d6 347 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 32 340 3.6E-88 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 UA74_09830 af16c20c54b70fa21fb0d0baee1a27d6 347 SUPERFAMILY SSF142754 32 340 2.35E-101 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 UA74_17910 cbbcd3865471db25e3043c52e5f26f9f 243 SUPERFAMILY SSF46955 4 99 7.69E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_17910 cbbcd3865471db25e3043c52e5f26f9f 243 SMART SM00422 1 70 5.3E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_17910 cbbcd3865471db25e3043c52e5f26f9f 243 Pfam PF00376 MerR family regulatory protein 4 39 1.3E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_17910 cbbcd3865471db25e3043c52e5f26f9f 243 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.8E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_17910 cbbcd3865471db25e3043c52e5f26f9f 243 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 7.8E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_17910 cbbcd3865471db25e3043c52e5f26f9f 243 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.8E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_11685 829d18ac110da251db2b35d0146b5414 866 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 394 417 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_11685 829d18ac110da251db2b35d0146b5414 866 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 508 520 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_11685 829d18ac110da251db2b35d0146b5414 866 Gene3D G3DSA:3.30.200.20 375 470 2.4E-24 T 12-10-2018 UA74_11685 829d18ac110da251db2b35d0146b5414 866 Pfam PF00069 Protein kinase domain 389 609 5.3E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_11685 829d18ac110da251db2b35d0146b5414 866 SMART SM00220 388 645 1.0E-46 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_11685 829d18ac110da251db2b35d0146b5414 866 Gene3D G3DSA:1.10.510.10 471 649 2.2E-33 T 12-10-2018 UA74_11685 829d18ac110da251db2b35d0146b5414 866 SUPERFAMILY SSF56112 386 639 6.47E-60 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_05275 ac1409e12c64bfe46841ad8b1267382a 214 Pfam PF13460 NAD(P)H-binding 8 201 5.0E-18 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_05275 ac1409e12c64bfe46841ad8b1267382a 214 Gene3D G3DSA:3.40.50.720 3 214 1.2E-34 T 12-10-2018 UA74_05275 ac1409e12c64bfe46841ad8b1267382a 214 SUPERFAMILY SSF51735 3 210 2.12E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_06035 120309ce67b54b3da4d6b853f4a9b611 142 ProSitePatterns PS00934 Glyoxalase I signature 1. 7 28 - T 12-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 UA74_06035 120309ce67b54b3da4d6b853f4a9b611 142 Gene3D G3DSA:3.10.180.10 1 141 7.2E-46 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_06035 120309ce67b54b3da4d6b853f4a9b611 142 SUPERFAMILY SSF54593 3 140 1.06E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_06035 120309ce67b54b3da4d6b853f4a9b611 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 136 3.5E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_01060 a31f07893ea20b77059d9e765ca2696b 393 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 261 327 3.2E-15 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_01060 a31f07893ea20b77059d9e765ca2696b 393 Pfam PF00005 ABC transporter 58 209 1.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_01060 a31f07893ea20b77059d9e765ca2696b 393 SMART SM00382 66 259 4.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01060 a31f07893ea20b77059d9e765ca2696b 393 Gene3D G3DSA:3.40.50.300 27 364 4.9E-103 T 12-10-2018 UA74_01060 a31f07893ea20b77059d9e765ca2696b 393 SUPERFAMILY SSF52540 30 281 1.3E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01060 a31f07893ea20b77059d9e765ca2696b 393 ProSitePatterns PS00211 ABC transporters family signature. 182 196 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_01060 a31f07893ea20b77059d9e765ca2696b 393 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 260 349 1.2E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_05615 631b5d589c4b6c410e0cf2261d597a0f 328 SUPERFAMILY SSF53850 115 286 1.98E-10 T 12-10-2018 UA74_05615 631b5d589c4b6c410e0cf2261d597a0f 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 71 328 5.6E-32 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 UA74_05615 631b5d589c4b6c410e0cf2261d597a0f 328 PIRSF PIRSF017082 1 328 3.3E-96 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 UA74_05615 631b5d589c4b6c410e0cf2261d597a0f 328 Gene3D G3DSA:3.40.190.10 132 256 6.4E-69 T 12-10-2018 UA74_05615 631b5d589c4b6c410e0cf2261d597a0f 328 Gene3D G3DSA:3.40.190.150 36 321 6.4E-69 T 12-10-2018 UA74_08150 cb2ceb00dce66009b331a1584986d805 278 Pfam PF01061 ABC-2 type transporter 28 241 2.8E-16 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_08150 cb2ceb00dce66009b331a1584986d805 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 219 238 9.8E-12 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_08150 cb2ceb00dce66009b331a1584986d805 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 9.8E-12 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_08150 cb2ceb00dce66009b331a1584986d805 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 46 67 9.8E-12 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_08150 cb2ceb00dce66009b331a1584986d805 278 PRINTS PR00164 ABC-2 type transport system membrane protein signature 161 185 9.8E-12 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_08150 cb2ceb00dce66009b331a1584986d805 278 PIRSF PIRSF006648 1 277 9.3E-26 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_13345 0839565a14724157d08fffc94656279e 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 107 2.8E-24 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_13345 0839565a14724157d08fffc94656279e 381 Pfam PF13378 Enolase C-terminal domain-like 129 354 8.8E-56 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_13345 0839565a14724157d08fffc94656279e 381 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_13345 0839565a14724157d08fffc94656279e 381 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UA74_13345 0839565a14724157d08fffc94656279e 381 SUPERFAMILY SSF54826 1 112 1.21E-31 T 12-10-2018 UA74_13345 0839565a14724157d08fffc94656279e 381 Gene3D G3DSA:3.30.390.10 11 373 2.2E-134 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_13345 0839565a14724157d08fffc94656279e 381 SMART SM00922 125 230 1.2E-15 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_13345 0839565a14724157d08fffc94656279e 381 Gene3D G3DSA:3.20.20.120 102 343 2.2E-134 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_13345 0839565a14724157d08fffc94656279e 381 SUPERFAMILY SSF51604 95 358 5.53E-70 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_05665 3461adcf8c5fa1fccd2e0caceae64266 201 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 6.0E-63 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_05665 3461adcf8c5fa1fccd2e0caceae64266 201 SUPERFAMILY SSF51182 1 196 5.18E-63 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_05665 3461adcf8c5fa1fccd2e0caceae64266 201 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 178 5.0E-50 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_05665 3461adcf8c5fa1fccd2e0caceae64266 201 Gene3D G3DSA:2.60.120.10 1 200 7.0E-63 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_14705 13c7d4fa10eac6b37bf9354c13467af1 115 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 112 25.124 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 UA74_14705 13c7d4fa10eac6b37bf9354c13467af1 115 Gene3D G3DSA:2.20.28.270 1 80 2.5E-37 T 12-10-2018 IPR038638 RbpA superfamily UA74_14705 13c7d4fa10eac6b37bf9354c13467af1 115 Pfam PF13397 RNA polymerase-binding protein 4 107 1.9E-42 T 12-10-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 UA74_14315 6c939cb61f6150e1c525b8fad77fe4d4 367 SUPERFAMILY SSF75005 94 349 5.8E-30 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_14315 6c939cb61f6150e1c525b8fad77fe4d4 367 Gene3D G3DSA:2.115.10.20 82 357 1.1E-26 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_14315 6c939cb61f6150e1c525b8fad77fe4d4 367 Pfam PF04616 Glycosyl hydrolases family 43 97 310 6.1E-8 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_22530 8803553d8ecc46cd47e62a4604578feb 323 Gene3D G3DSA:3.30.470.20 213 319 2.2E-7 T 12-10-2018 UA74_22530 8803553d8ecc46cd47e62a4604578feb 323 SUPERFAMILY SSF56059 135 311 3.03E-16 T 12-10-2018 UA74_09545 25866d15525585f35e1956fe5b0c7850 144 SMART SM00530 12 67 1.2E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_09545 25866d15525585f35e1956fe5b0c7850 144 Pfam PF13560 Helix-turn-helix domain 8 65 1.5E-9 T 12-10-2018 UA74_09545 25866d15525585f35e1956fe5b0c7850 144 SUPERFAMILY SSF47413 4 71 5.91E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_09545 25866d15525585f35e1956fe5b0c7850 144 Gene3D G3DSA:1.10.260.40 3 82 5.7E-15 T 12-10-2018 UA74_27700 fb543d76f415c7c874586b65cef37b62 230 SUPERFAMILY SSF51261 91 223 9.94E-46 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_27700 fb543d76f415c7c874586b65cef37b62 230 Pfam PF01551 Peptidase family M23 123 219 1.0E-30 T 12-10-2018 IPR016047 Peptidase M23 UA74_27700 fb543d76f415c7c874586b65cef37b62 230 Gene3D G3DSA:2.70.70.10 67 226 5.5E-43 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_17010 c3a4a3942801f3b8d1c237014a725d38 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 1.0E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_17010 c3a4a3942801f3b8d1c237014a725d38 225 Gene3D G3DSA:1.10.10.10 11 78 1.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17010 c3a4a3942801f3b8d1c237014a725d38 225 SUPERFAMILY SSF48008 86 215 2.88E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_17010 c3a4a3942801f3b8d1c237014a725d38 225 SMART SM00345 19 77 4.8E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_17010 c3a4a3942801f3b8d1c237014a725d38 225 SUPERFAMILY SSF46785 10 81 2.63E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_17010 c3a4a3942801f3b8d1c237014a725d38 225 Gene3D G3DSA:1.20.120.530 81 217 6.8E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_17010 c3a4a3942801f3b8d1c237014a725d38 225 SMART SM00895 87 211 1.2E-17 T 12-10-2018 IPR011711 GntR, C-terminal UA74_17010 c3a4a3942801f3b8d1c237014a725d38 225 Pfam PF07729 FCD domain 87 209 1.2E-23 T 12-10-2018 IPR011711 GntR, C-terminal UA74_25980 60c6e2e2bbcc56de7473cb514acf6fca 684 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 133 145 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 UA74_25980 60c6e2e2bbcc56de7473cb514acf6fca 684 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_25980 60c6e2e2bbcc56de7473cb514acf6fca 684 Gene3D G3DSA:3.30.200.20 5 93 1.3E-20 T 12-10-2018 UA74_25980 60c6e2e2bbcc56de7473cb514acf6fca 684 Pfam PF00069 Protein kinase domain 15 261 4.4E-35 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_25980 60c6e2e2bbcc56de7473cb514acf6fca 684 Gene3D G3DSA:1.10.510.10 95 270 4.8E-40 T 12-10-2018 UA74_25980 60c6e2e2bbcc56de7473cb514acf6fca 684 SUPERFAMILY SSF56112 11 267 1.75E-61 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_17200 db09bcfbdd3db55d32d802e48ba6fd01 274 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 3.5E-70 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_17200 db09bcfbdd3db55d32d802e48ba6fd01 274 Hamap MF_01974 Methionine aminopeptidase [map]. 2 254 31.863 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_17200 db09bcfbdd3db55d32d802e48ba6fd01 274 Pfam PF00557 Metallopeptidase family M24 13 245 1.7E-43 T 12-10-2018 IPR000994 Peptidase M24 UA74_17200 db09bcfbdd3db55d32d802e48ba6fd01 274 SUPERFAMILY SSF55920 2 253 1.23E-69 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like UA74_17200 db09bcfbdd3db55d32d802e48ba6fd01 274 Gene3D G3DSA:3.90.230.10 1 262 7.2E-77 T 12-10-2018 UA74_17200 db09bcfbdd3db55d32d802e48ba6fd01 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 8.2E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_17200 db09bcfbdd3db55d32d802e48ba6fd01 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 8.2E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_17200 db09bcfbdd3db55d32d802e48ba6fd01 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 8.2E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_17200 db09bcfbdd3db55d32d802e48ba6fd01 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 8.2E-17 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_27280 28075a1e81773a82582658029e682eb8 201 Gene3D G3DSA:3.30.420.10 4 180 4.2E-38 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_27280 28075a1e81773a82582658029e682eb8 201 Pfam PF00929 Exonuclease 10 169 1.4E-20 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_27280 28075a1e81773a82582658029e682eb8 201 SMART SM00479 8 178 6.7E-33 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_27280 28075a1e81773a82582658029e682eb8 201 SUPERFAMILY SSF53098 8 190 3.71E-36 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_06100 c4f7ad7b1cbbdec7715e0bc41462f312 150 Pfam PF12680 SnoaL-like domain 10 119 2.0E-15 T 12-10-2018 IPR037401 SnoaL-like domain UA74_06100 c4f7ad7b1cbbdec7715e0bc41462f312 150 Gene3D G3DSA:3.10.450.50 7 136 4.5E-23 T 12-10-2018 UA74_06100 c4f7ad7b1cbbdec7715e0bc41462f312 150 SUPERFAMILY SSF54427 9 132 6.53E-21 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_21790 9c6e2db9528940f0b4672c75fe5487dc 217 SUPERFAMILY SSF82607 28 113 2.09E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_21790 9c6e2db9528940f0b4672c75fe5487dc 217 Gene3D G3DSA:3.30.1310.10 20 119 5.8E-6 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_21790 9c6e2db9528940f0b4672c75fe5487dc 217 Pfam PF02575 YbaB/EbfC DNA-binding family 34 113 3.1E-10 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_20345 90fa575381622b9baef62178fa20c2d4 79 Gene3D G3DSA:1.20.120.450 6 45 1.1E-5 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_20345 90fa575381622b9baef62178fa20c2d4 79 SUPERFAMILY SSF109854 15 42 4.39E-5 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_20345 90fa575381622b9baef62178fa20c2d4 79 Pfam PF04978 Protein of unknown function (DUF664) 16 43 1.8E-9 T 12-10-2018 IPR007061 Protein of unknown function DUF664 UA74_19290 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Pfam PF00754 F5/8 type C domain 54 166 3.0E-26 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_19290 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Pfam PF00754 F5/8 type C domain 620 719 1.4E-22 T 12-10-2018 IPR000421 Coagulation factor 5/8 C-terminal domain UA74_19290 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Gene3D G3DSA:3.20.20.80 192 462 3.1E-25 T 12-10-2018 UA74_19290 2aadb2d1f52a6eeb56479bdeccd82a1f 725 SUPERFAMILY SSF51445 183 453 7.43E-33 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_19290 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Gene3D G3DSA:2.60.120.260 48 171 4.2E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_19290 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Gene3D G3DSA:2.60.120.260 593 723 2.4E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_19290 2aadb2d1f52a6eeb56479bdeccd82a1f 725 SUPERFAMILY SSF49785 588 723 4.47E-28 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_19290 2aadb2d1f52a6eeb56479bdeccd82a1f 725 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 279 405 2.4E-6 T 12-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 UA74_19290 2aadb2d1f52a6eeb56479bdeccd82a1f 725 SUPERFAMILY SSF49785 49 171 1.63E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_17505 1c4d74632eae31d03c4294fa51b67dd0 118 Gene3D G3DSA:1.10.10.10 2 108 1.0E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17505 1c4d74632eae31d03c4294fa51b67dd0 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_17505 1c4d74632eae31d03c4294fa51b67dd0 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 2.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_17505 1c4d74632eae31d03c4294fa51b67dd0 118 SMART SM00418 8 86 1.9E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_17505 1c4d74632eae31d03c4294fa51b67dd0 118 Pfam PF12840 Helix-turn-helix domain 8 62 1.2E-15 T 12-10-2018 UA74_17505 1c4d74632eae31d03c4294fa51b67dd0 118 SUPERFAMILY SSF46785 4 99 3.22E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_27155 ab78542215f8d38617d811e2207ad25a 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 6.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_27155 ab78542215f8d38617d811e2207ad25a 209 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 87 189 1.1E-10 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal UA74_27155 ab78542215f8d38617d811e2207ad25a 209 Gene3D G3DSA:1.10.357.10 4 197 7.8E-36 T 12-10-2018 UA74_27155 ab78542215f8d38617d811e2207ad25a 209 SUPERFAMILY SSF48498 86 190 1.05E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_27155 ab78542215f8d38617d811e2207ad25a 209 SUPERFAMILY SSF46689 5 77 4.93E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_17995 89313fedba079b24aa7aecd50704b080 555 SUPERFAMILY SSF51905 18 522 2.75E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17995 89313fedba079b24aa7aecd50704b080 555 Gene3D G3DSA:3.50.50.60 20 107 2.9E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17995 89313fedba079b24aa7aecd50704b080 555 Pfam PF01593 Flavin containing amine oxidoreductase 30 405 8.3E-12 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_17995 89313fedba079b24aa7aecd50704b080 555 Gene3D G3DSA:3.50.50.60 205 326 9.2E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_20455 a66506c71e3a28c5ccb1573c278fc5fb 283 Gene3D G3DSA:2.40.30.10 20 156 1.3E-28 T 12-10-2018 UA74_20455 a66506c71e3a28c5ccb1573c278fc5fb 283 Pfam PF04954 Siderophore-interacting protein 168 279 3.6E-32 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain UA74_20455 a66506c71e3a28c5ccb1573c278fc5fb 283 SUPERFAMILY SSF63380 30 151 3.71E-6 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_20455 a66506c71e3a28c5ccb1573c278fc5fb 283 Pfam PF08021 Siderophore-interacting FAD-binding domain 39 150 1.8E-26 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting UA74_20455 a66506c71e3a28c5ccb1573c278fc5fb 283 Gene3D G3DSA:3.40.50.80 161 283 4.9E-34 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_12810 39dd427d6c173c50c78af8b650a58843 344 Pfam PF00962 Adenosine/AMP deaminase 15 328 6.9E-70 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 UA74_12810 39dd427d6c173c50c78af8b650a58843 344 SUPERFAMILY SSF51556 10 334 3.68E-73 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_12810 39dd427d6c173c50c78af8b650a58843 344 Gene3D G3DSA:3.20.20.140 5 339 5.0E-90 T 12-10-2018 UA74_12810 39dd427d6c173c50c78af8b650a58843 344 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 15 331 1.7E-81 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 UA74_08085 14edaef9d599441ac13aee21741a0b19 428 PIRSF PIRSF016521 3 428 1.4E-64 T 12-10-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 UA74_08085 14edaef9d599441ac13aee21741a0b19 428 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 195 427 1.8E-29 T 12-10-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal UA74_08085 14edaef9d599441ac13aee21741a0b19 428 SUPERFAMILY SSF53474 63 427 8.46E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08085 14edaef9d599441ac13aee21741a0b19 428 Gene3D G3DSA:2.60.40.2240 1 120 3.7E-15 T 12-10-2018 UA74_08085 14edaef9d599441ac13aee21741a0b19 428 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 24 128 2.9E-17 T 12-10-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase UA74_08085 14edaef9d599441ac13aee21741a0b19 428 Gene3D G3DSA:3.40.50.1820 123 427 1.3E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20525 40a7fe97a72fbe795b0bb13b4945e6a3 1086 Gene3D G3DSA:3.40.50.200 178 472 1.9E-91 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_20525 40a7fe97a72fbe795b0bb13b4945e6a3 1086 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 244 254 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UA74_20525 40a7fe97a72fbe795b0bb13b4945e6a3 1086 SUPERFAMILY SSF52743 186 470 2.49E-81 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_20525 40a7fe97a72fbe795b0bb13b4945e6a3 1086 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 411 421 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_20525 40a7fe97a72fbe795b0bb13b4945e6a3 1086 PRINTS PR00723 Subtilisin serine protease family (S8) signature 202 221 4.0E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_20525 40a7fe97a72fbe795b0bb13b4945e6a3 1086 PRINTS PR00723 Subtilisin serine protease family (S8) signature 240 253 4.0E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_20525 40a7fe97a72fbe795b0bb13b4945e6a3 1086 PRINTS PR00723 Subtilisin serine protease family (S8) signature 410 426 4.0E-21 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_20525 40a7fe97a72fbe795b0bb13b4945e6a3 1086 Pfam PF00082 Subtilase family 202 458 2.4E-57 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 Gene3D G3DSA:3.40.1190.20 1 217 2.4E-63 T 12-10-2018 IPR029056 Ribokinase-like UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 PRINTS PR00990 Ribokinase signature 101 114 1.3E-25 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 PRINTS PR00990 Ribokinase signature 3 24 1.3E-25 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 PRINTS PR00990 Ribokinase signature 30 49 1.3E-25 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 PRINTS PR00990 Ribokinase signature 169 184 1.3E-25 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 284 297 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 SUPERFAMILY SSF53613 1 337 2.34E-74 T 12-10-2018 IPR029056 Ribokinase-like UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 Pfam PF00294 pfkB family carbohydrate kinase 225 332 3.4E-24 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 Pfam PF00294 pfkB family carbohydrate kinase 1 203 6.9E-39 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 Gene3D G3DSA:3.40.1190.20 220 337 3.6E-30 T 12-10-2018 IPR029056 Ribokinase-like UA74_30150 a6288bb57e926e9a8567f581a0861c99 338 Hamap MF_01987 Ribokinase [rbsK]. 1 338 23.145 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 UA74_26390 73179f38a1aca92cd0ef3860b4985d11 204 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 178 9.0E-60 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_26390 73179f38a1aca92cd0ef3860b4985d11 204 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 4.1E-56 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UA74_26390 73179f38a1aca92cd0ef3860b4985d11 204 Gene3D G3DSA:2.60.120.10 1 203 3.0E-65 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_26390 73179f38a1aca92cd0ef3860b4985d11 204 SUPERFAMILY SSF51182 2 196 8.9E-67 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_09765 c7ebc0ef8d481628c0519e48dfa4dabd 370 SUPERFAMILY SSF46785 5 49 5.21E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_09765 c7ebc0ef8d481628c0519e48dfa4dabd 370 Pfam PF13404 AsnC-type helix-turn-helix domain 5 44 4.0E-7 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_09765 c7ebc0ef8d481628c0519e48dfa4dabd 370 Gene3D G3DSA:1.10.10.10 5 49 1.4E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19695 09635768c5a77479701566665c092206 509 SUPERFAMILY SSF48179 415 498 5.02E-12 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_19695 09635768c5a77479701566665c092206 509 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3 182 1.0E-51 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UA74_19695 09635768c5a77479701566665c092206 509 Gene3D G3DSA:3.30.750.190 288 412 8.1E-73 T 12-10-2018 UA74_19695 09635768c5a77479701566665c092206 509 SUPERFAMILY SSF48179 183 285 1.28E-22 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_19695 09635768c5a77479701566665c092206 509 Gene3D G3DSA:3.40.50.720 2 186 5.4E-56 T 12-10-2018 UA74_19695 09635768c5a77479701566665c092206 509 SUPERFAMILY SSF51735 3 183 5.39E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_19695 09635768c5a77479701566665c092206 509 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 184 280 1.0E-20 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UA74_19695 09635768c5a77479701566665c092206 509 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 417 498 3.6E-11 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UA74_19695 09635768c5a77479701566665c092206 509 Gene3D G3DSA:1.10.1040.50 187 495 8.1E-73 T 12-10-2018 UA74_22125 2e2db54b4619f0661c32e71956d3d790 220 Gene3D G3DSA:3.40.50.1110 20 203 3.9E-38 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_22125 2e2db54b4619f0661c32e71956d3d790 220 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 23 192 3.5E-29 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain UA74_22125 2e2db54b4619f0661c32e71956d3d790 220 SUPERFAMILY SSF52266 17 202 5.19E-38 T 12-10-2018 UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 ProSitePatterns PS00211 ABC transporters family signature. 384 398 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 Pfam PF00005 ABC transporter 266 412 4.5E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 SUPERFAMILY SSF52540 241 459 1.26E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 SUPERFAMILY SSF52540 3 225 1.02E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 SMART SM00382 28 211 8.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 SMART SM00382 271 460 7.0E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 Gene3D G3DSA:3.40.50.300 2 242 8.2E-56 T 12-10-2018 UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 Gene3D G3DSA:3.40.50.300 243 462 2.5E-50 T 12-10-2018 UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_16635 ceb38acf74600cb76f1e5219874fbe85 462 Pfam PF00005 ABC transporter 20 175 2.1E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_18085 8e74c5aff00604c482c19b17d8b32c34 357 Gene3D G3DSA:3.40.50.2300 70 326 2.1E-68 T 12-10-2018 UA74_18085 8e74c5aff00604c482c19b17d8b32c34 357 SUPERFAMILY SSF53822 77 355 3.14E-54 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_18085 8e74c5aff00604c482c19b17d8b32c34 357 SMART SM00354 16 86 1.2E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_18085 8e74c5aff00604c482c19b17d8b32c34 357 SUPERFAMILY SSF47413 16 74 4.64E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_18085 8e74c5aff00604c482c19b17d8b32c34 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 20 63 8.9E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_18085 8e74c5aff00604c482c19b17d8b32c34 357 Pfam PF13377 Periplasmic binding protein-like domain 182 349 5.3E-32 T 12-10-2018 UA74_18085 8e74c5aff00604c482c19b17d8b32c34 357 Gene3D G3DSA:3.40.50.2300 174 310 2.1E-68 T 12-10-2018 UA74_18085 8e74c5aff00604c482c19b17d8b32c34 357 Gene3D G3DSA:1.10.260.40 11 69 1.1E-19 T 12-10-2018 UA74_00500 67358f2fa99316d68ff0fddf1f42f4c0 186 SUPERFAMILY SSF47240 14 157 3.45E-42 T 12-10-2018 IPR009078 Ferritin-like superfamily UA74_00500 67358f2fa99316d68ff0fddf1f42f4c0 186 Gene3D G3DSA:1.20.1260.10 6 186 3.1E-49 T 12-10-2018 IPR012347 Ferritin-like UA74_00500 67358f2fa99316d68ff0fddf1f42f4c0 186 Pfam PF00210 Ferritin-like domain 18 152 2.1E-33 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 SUPERFAMILY SSF51905 4 311 3.42E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 67 77 2.0E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 2.0E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 2.0E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 123 2.0E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.5E-17 T 12-10-2018 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 1.5E-17 T 12-10-2018 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.5E-17 T 12-10-2018 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 Hamap MF_01685 Ferredoxin--NADP reductase. 8 328 37.204 T 12-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 Gene3D G3DSA:3.50.50.60 130 246 1.6E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 296 4.8E-32 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_04125 d9ef3856e4bc5adb1e73e8374d829466 328 Gene3D G3DSA:3.50.50.60 10 307 1.6E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_07420 c8720cbef7199eb11733a7084ee49c04 294 SMART SM00530 19 74 4.7E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_07420 c8720cbef7199eb11733a7084ee49c04 294 Pfam PF13560 Helix-turn-helix domain 15 77 2.8E-11 T 12-10-2018 UA74_07420 c8720cbef7199eb11733a7084ee49c04 294 SUPERFAMILY SSF47413 14 70 1.74E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_07420 c8720cbef7199eb11733a7084ee49c04 294 Gene3D G3DSA:1.10.260.40 1 78 3.9E-10 T 12-10-2018 UA74_15230 cc14553a689a0f64781fe05c7d752cd8 213 Gene3D G3DSA:1.10.357.10 5 191 1.3E-25 T 12-10-2018 UA74_15230 cc14553a689a0f64781fe05c7d752cd8 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 9.1E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15230 cc14553a689a0f64781fe05c7d752cd8 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15230 cc14553a689a0f64781fe05c7d752cd8 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15230 cc14553a689a0f64781fe05c7d752cd8 213 SUPERFAMILY SSF46689 4 72 7.09E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_04370 27212da5482233c273785c6155b157da 595 PIRSF PIRSF002741 30 231 1.1E-6 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_04370 27212da5482233c273785c6155b157da 595 PIRSF PIRSF002741 249 594 2.2E-41 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_04370 27212da5482233c273785c6155b157da 595 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 113 512 1.6E-53 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_04370 27212da5482233c273785c6155b157da 595 Gene3D G3DSA:3.40.190.10 36 340 5.1E-35 T 12-10-2018 UA74_04370 27212da5482233c273785c6155b157da 595 SUPERFAMILY SSF53850 61 592 1.27E-75 T 12-10-2018 UA74_04370 27212da5482233c273785c6155b157da 595 Gene3D G3DSA:3.10.105.10 341 560 9.8E-44 T 12-10-2018 UA74_07485 6f6ad1089e1893c0cb9e99cdd0179f8b 136 Gene3D G3DSA:3.10.180.10 2 136 8.5E-38 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_07485 6f6ad1089e1893c0cb9e99cdd0179f8b 136 SUPERFAMILY SSF54593 3 134 3.49E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_07485 6f6ad1089e1893c0cb9e99cdd0179f8b 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 2.3E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_20620 763be1ab396530e33af38eb99bf1de41 390 Gene3D G3DSA:2.115.10.20 31 340 3.6E-80 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_20620 763be1ab396530e33af38eb99bf1de41 390 SUPERFAMILY SSF75005 35 348 1.01E-56 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_20620 763be1ab396530e33af38eb99bf1de41 390 Pfam PF04616 Glycosyl hydrolases family 43 36 331 1.8E-54 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_08115 4c797ad814a9880afa2e486b0f3dbf56 771 Pfam PF00384 Molybdopterin oxidoreductase 121 501 1.3E-28 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_08115 4c797ad814a9880afa2e486b0f3dbf56 771 Pfam PF01568 Molydopterin dinucleotide binding domain 653 762 2.2E-9 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 UA74_08115 4c797ad814a9880afa2e486b0f3dbf56 771 PIRSF PIRSF000144 3 771 0.0 T 12-10-2018 UA74_08115 4c797ad814a9880afa2e486b0f3dbf56 771 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 769 8.4E-300 T 12-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 UA74_08115 4c797ad814a9880afa2e486b0f3dbf56 771 SUPERFAMILY SSF53706 59 644 1.07E-140 T 12-10-2018 UA74_08115 4c797ad814a9880afa2e486b0f3dbf56 771 Gene3D G3DSA:2.40.40.20 652 769 6.1E-5 T 12-10-2018 UA74_08115 4c797ad814a9880afa2e486b0f3dbf56 771 SUPERFAMILY SSF50692 650 770 2.49E-16 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily UA74_08115 4c797ad814a9880afa2e486b0f3dbf56 771 Gene3D G3DSA:3.40.228.10 197 419 2.9E-72 T 12-10-2018 UA74_08115 4c797ad814a9880afa2e486b0f3dbf56 771 Gene3D G3DSA:3.40.50.740 129 595 2.9E-72 T 12-10-2018 UA74_24185 2f1c20393e5e9f6905cff9e9372a0fea 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 269 1.8E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_24185 2f1c20393e5e9f6905cff9e9372a0fea 284 SUPERFAMILY SSF161098 8 284 2.24E-57 T 12-10-2018 IPR035906 MetI-like superfamily UA74_24185 2f1c20393e5e9f6905cff9e9372a0fea 284 Gene3D G3DSA:1.10.3720.10 4 275 1.2E-54 T 12-10-2018 IPR035906 MetI-like superfamily UA74_17085 c9f72ed50d6e587285d2b01dafb278a0 385 SUPERFAMILY SSF52283 3 167 8.72E-59 T 12-10-2018 UA74_17085 c9f72ed50d6e587285d2b01dafb278a0 385 Hamap MF_03210 Formate dehydrogenase, mitochondrial. 2 384 53.064 T 12-10-2018 IPR033689 NAD-dependent formate dehydrogenase GO:0008863 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 UA74_17085 c9f72ed50d6e587285d2b01dafb278a0 385 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 156 336 2.6E-44 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_17085 c9f72ed50d6e587285d2b01dafb278a0 385 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 63 363 1.3E-17 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UA74_17085 c9f72ed50d6e587285d2b01dafb278a0 385 Gene3D G3DSA:3.40.50.720 2 376 6.8E-191 T 12-10-2018 UA74_17085 c9f72ed50d6e587285d2b01dafb278a0 385 SUPERFAMILY SSF51735 150 337 3.56E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17085 c9f72ed50d6e587285d2b01dafb278a0 385 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 196 223 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UA74_17085 c9f72ed50d6e587285d2b01dafb278a0 385 Gene3D G3DSA:3.40.50.720 147 339 6.8E-191 T 12-10-2018 UA74_08250 d8f697ba16e23123a1a97f1d852e6b32 187 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 186 27.131 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 UA74_08250 d8f697ba16e23123a1a97f1d852e6b32 187 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 1 185 4.3E-54 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 UA74_08250 d8f697ba16e23123a1a97f1d852e6b32 187 SUPERFAMILY SSF52374 1 186 9.7E-50 T 12-10-2018 UA74_08250 d8f697ba16e23123a1a97f1d852e6b32 187 Gene3D G3DSA:3.40.50.620 1 187 4.0E-59 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_08250 d8f697ba16e23123a1a97f1d852e6b32 187 Pfam PF01467 Cytidylyltransferase-like 2 160 4.5E-30 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_08250 d8f697ba16e23123a1a97f1d852e6b32 187 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 62 5.4E-9 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_18055 6490a9209550d33a59dfdfc23e7333a0 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 8.9E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_18055 6490a9209550d33a59dfdfc23e7333a0 208 SUPERFAMILY SSF46689 10 87 4.0E-21 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_18055 6490a9209550d33a59dfdfc23e7333a0 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.2E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_18055 6490a9209550d33a59dfdfc23e7333a0 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.2E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_18055 6490a9209550d33a59dfdfc23e7333a0 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 65 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_18055 6490a9209550d33a59dfdfc23e7333a0 208 Gene3D G3DSA:1.10.357.10 18 205 2.3E-45 T 12-10-2018 UA74_10640 b7c37c28f1a46d92b8fdf24603d34808 147 Gene3D G3DSA:3.10.180.10 24 146 6.2E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_10640 b7c37c28f1a46d92b8fdf24603d34808 147 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 23 139 1.5E-10 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_10640 b7c37c28f1a46d92b8fdf24603d34808 147 SUPERFAMILY SSF54593 22 139 3.49E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_05030 ab88792843963975e7a3227768867f2f 818 Pfam PF04851 Type III restriction enzyme, res subunit 18 206 1.9E-19 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_05030 ab88792843963975e7a3227768867f2f 818 Gene3D G3DSA:3.40.50.300 222 403 1.5E-22 T 12-10-2018 UA74_05030 ab88792843963975e7a3227768867f2f 818 Gene3D G3DSA:3.40.50.300 9 221 5.1E-15 T 12-10-2018 UA74_05030 ab88792843963975e7a3227768867f2f 818 SUPERFAMILY SSF52540 39 376 3.23E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16680 f5b68a13f6a13343e8dadcfbc5f27d28 484 SUPERFAMILY SSF52794 3 98 7.67E-31 T 12-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UA74_16680 f5b68a13f6a13343e8dadcfbc5f27d28 484 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 86 8.2E-30 T 12-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 UA74_16680 f5b68a13f6a13343e8dadcfbc5f27d28 484 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 86 1.9E-18 T 12-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UA74_16680 f5b68a13f6a13343e8dadcfbc5f27d28 484 Gene3D G3DSA:3.40.50.2300 1 104 2.7E-36 T 12-10-2018 UA74_16680 f5b68a13f6a13343e8dadcfbc5f27d28 484 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 128 462 1.3E-104 T 12-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 UA74_00725 750324e52ea2dbf13f62009be6e2c134 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 23 83 2.5E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_00725 750324e52ea2dbf13f62009be6e2c134 324 Gene3D G3DSA:3.40.50.720 116 258 2.5E-102 T 12-10-2018 UA74_00725 750324e52ea2dbf13f62009be6e2c134 324 SMART SM00829 6 322 2.3E-43 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_00725 750324e52ea2dbf13f62009be6e2c134 324 SUPERFAMILY SSF51735 107 265 4.96E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_00725 750324e52ea2dbf13f62009be6e2c134 324 Pfam PF00107 Zinc-binding dehydrogenase 147 261 1.6E-27 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_00725 750324e52ea2dbf13f62009be6e2c134 324 Gene3D G3DSA:3.90.180.10 9 322 2.5E-102 T 12-10-2018 UA74_00725 750324e52ea2dbf13f62009be6e2c134 324 SUPERFAMILY SSF50129 2 134 6.6E-36 T 12-10-2018 IPR011032 GroES-like superfamily UA74_00725 750324e52ea2dbf13f62009be6e2c134 324 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 2 323 1.9E-133 T 12-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 UA74_14720 319f9233070cd515cdc3e33a092082e1 233 Gene3D G3DSA:3.20.20.190 1 226 1.7E-57 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_14720 319f9233070cd515cdc3e33a092082e1 233 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 2 217 2.7E-30 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UA74_14720 319f9233070cd515cdc3e33a092082e1 233 SUPERFAMILY SSF51695 2 221 2.88E-48 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_19550 2d3ed58ca3a6290255cda069b8067c46 303 Gene3D G3DSA:3.20.20.70 1 297 2.1E-84 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_19550 2d3ed58ca3a6290255cda069b8067c46 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 5.1E-11 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_19550 2d3ed58ca3a6290255cda069b8067c46 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 5.1E-11 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_19550 2d3ed58ca3a6290255cda069b8067c46 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 5.1E-11 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_19550 2d3ed58ca3a6290255cda069b8067c46 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 5.1E-11 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_19550 2d3ed58ca3a6290255cda069b8067c46 303 SMART SM01130 4 294 9.3E-61 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_19550 2d3ed58ca3a6290255cda069b8067c46 303 Pfam PF00701 Dihydrodipicolinate synthetase family 6 292 7.9E-44 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_19550 2d3ed58ca3a6290255cda069b8067c46 303 SUPERFAMILY SSF51569 6 293 2.93E-66 T 12-10-2018 UA74_19550 2d3ed58ca3a6290255cda069b8067c46 303 PIRSF PIRSF001365 1 300 1.6E-60 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_27510 dedb10bd064317f07c4374a3bab7a658 267 Gene3D G3DSA:3.10.20.30 24 137 2.3E-31 T 12-10-2018 IPR012675 Beta-grasp domain superfamily UA74_27510 dedb10bd064317f07c4374a3bab7a658 267 SUPERFAMILY SSF46548 138 264 9.24E-33 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_27510 dedb10bd064317f07c4374a3bab7a658 267 Pfam PF13183 4Fe-4S dicluster domain 177 249 2.9E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_27510 dedb10bd064317f07c4374a3bab7a658 267 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 179 190 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_27510 dedb10bd064317f07c4374a3bab7a658 267 SUPERFAMILY SSF54292 30 137 5.11E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 UA74_27510 dedb10bd064317f07c4374a3bab7a658 267 Gene3D G3DSA:1.10.1060.10 138 266 2.5E-47 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_27510 dedb10bd064317f07c4374a3bab7a658 267 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 36 259 5.2E-78 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27510 dedb10bd064317f07c4374a3bab7a658 267 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 33 143 2.1E-33 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 Gene3D G3DSA:1.10.540.10 10 123 1.4E-29 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 SUPERFAMILY SSF47203 233 383 2.09E-54 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 Gene3D G3DSA:2.40.110.10 126 240 1.1E-36 T 12-10-2018 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 4.4E-24 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 PIRSF PIRSF016578 4 377 4.6E-22 T 12-10-2018 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 2.0E-47 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 122 3.6E-27 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 Gene3D G3DSA:1.20.140.10 241 384 5.7E-51 T 12-10-2018 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 SUPERFAMILY SSF56645 11 232 1.57E-69 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_02295 b6a2855c7183c8c7d111c751037431d0 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_03015 8ebb3252d70325de7fc93113368297d0 132 SUPERFAMILY SSF56047 3 132 3.14E-43 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03015 8ebb3252d70325de7fc93113368297d0 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 30.73 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03015 8ebb3252d70325de7fc93113368297d0 132 Gene3D G3DSA:3.30.1490.10 75 132 2.3E-22 T 12-10-2018 UA74_03015 8ebb3252d70325de7fc93113368297d0 132 Pfam PF00410 Ribosomal protein S8 5 132 9.3E-48 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03015 8ebb3252d70325de7fc93113368297d0 132 Gene3D G3DSA:3.30.1370.30 4 74 8.5E-27 T 12-10-2018 UA74_12085 337b995139667b3393e44037d7e91f1e 267 Pfam PF14428 SCP1.201-like deaminase 142 264 3.1E-18 T 12-10-2018 IPR032724 Deaminase, SCP1.201-like UA74_24825 8eb8433a07beb1505ac6050a15f5ab62 247 Pfam PF01553 Acyltransferase 21 151 5.9E-26 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_24825 8eb8433a07beb1505ac6050a15f5ab62 247 SMART SM00563 35 154 6.3E-36 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_24825 8eb8433a07beb1505ac6050a15f5ab62 247 SUPERFAMILY SSF69593 2 226 1.31E-54 T 12-10-2018 UA74_14235 26e237a22746c0983126cde66110a3e9 290 Gene3D G3DSA:1.10.1040.10 161 290 2.8E-35 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_14235 26e237a22746c0983126cde66110a3e9 290 SUPERFAMILY SSF51735 6 153 5.77E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14235 26e237a22746c0983126cde66110a3e9 290 Gene3D G3DSA:3.40.50.720 3 159 2.9E-37 T 12-10-2018 UA74_14235 26e237a22746c0983126cde66110a3e9 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 152 5.4E-21 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UA74_14235 26e237a22746c0983126cde66110a3e9 290 PIRSF PIRSF000103 1 290 6.1E-34 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_29500 ee9923775d3132c474be68eda33c51b8 469 Pfam PF01565 FAD binding domain 48 187 1.8E-42 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_29500 ee9923775d3132c474be68eda33c51b8 469 SUPERFAMILY SSF55103 198 465 1.23E-55 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 UA74_29500 ee9923775d3132c474be68eda33c51b8 469 Gene3D G3DSA:3.30.70.2740 343 425 2.3E-12 T 12-10-2018 UA74_29500 ee9923775d3132c474be68eda33c51b8 469 Gene3D G3DSA:1.10.45.10 426 465 1.8E-10 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 UA74_29500 ee9923775d3132c474be68eda33c51b8 469 Gene3D G3DSA:3.30.465.10 103 222 2.7E-48 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_29500 ee9923775d3132c474be68eda33c51b8 469 Gene3D G3DSA:3.30.43.10 4 100 9.4E-24 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 UA74_29500 ee9923775d3132c474be68eda33c51b8 469 SUPERFAMILY SSF56176 11 224 2.57E-77 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_29500 ee9923775d3132c474be68eda33c51b8 469 Pfam PF02913 FAD linked oxidases, C-terminal domain 224 464 4.2E-59 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 UA74_18955 0c1d1d24aaab0cb2b14741ff77ba0096 560 Pfam PF00561 alpha/beta hydrolase fold 105 501 3.4E-29 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_18955 0c1d1d24aaab0cb2b14741ff77ba0096 560 SUPERFAMILY SSF53474 103 501 5.08E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08650 41a958fda890b352d502b824b8d93263 957 SUPERFAMILY SSF51998 174 721 1.37E-129 T 12-10-2018 UA74_08650 41a958fda890b352d502b824b8d93263 957 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 70 153 3.2E-19 T 12-10-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08650 41a958fda890b352d502b824b8d93263 957 Pfam PF02867 Ribonucleotide reductase, barrel domain 174 709 4.5E-142 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_08650 41a958fda890b352d502b824b8d93263 957 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 93 719 1.1E-182 T 12-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08650 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 555 582 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_08650 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 410 433 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_08650 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 448 470 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_08650 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 249 268 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_08650 41a958fda890b352d502b824b8d93263 957 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 3.6E-12 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_08650 41a958fda890b352d502b824b8d93263 957 Gene3D G3DSA:3.20.70.20 79 725 1.1E-195 T 12-10-2018 UA74_16690 9ee62ef8e39ad48d7f98e9b5c7164721 314 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 295 3.7E-92 T 12-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 UA74_16690 9ee62ef8e39ad48d7f98e9b5c7164721 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_16690 9ee62ef8e39ad48d7f98e9b5c7164721 314 SUPERFAMILY SSF53613 2 291 3.74E-60 T 12-10-2018 IPR029056 Ribokinase-like UA74_16690 9ee62ef8e39ad48d7f98e9b5c7164721 314 PIRSF PIRSF000535 1 301 1.9E-68 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_16690 9ee62ef8e39ad48d7f98e9b5c7164721 314 Gene3D G3DSA:3.40.1190.20 1 305 2.2E-97 T 12-10-2018 IPR029056 Ribokinase-like UA74_16690 9ee62ef8e39ad48d7f98e9b5c7164721 314 Pfam PF00294 pfkB family carbohydrate kinase 15 291 8.2E-42 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_16690 9ee62ef8e39ad48d7f98e9b5c7164721 314 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 295 1.0E-94 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_22285 b052085a58ca581b229f9e53a8101e68 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 252 4.0E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_22285 b052085a58ca581b229f9e53a8101e68 267 SUPERFAMILY SSF161098 2 266 5.05E-63 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22285 b052085a58ca581b229f9e53a8101e68 267 Gene3D G3DSA:1.10.3720.10 1 257 1.5E-56 T 12-10-2018 IPR035906 MetI-like superfamily UA74_15785 dd67931736148373fa3d45b95bc85b84 311 Pfam PF01256 Carbohydrate kinase 28 289 3.5E-26 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_15785 dd67931736148373fa3d45b95bc85b84 311 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 5 299 15.672 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 UA74_15785 dd67931736148373fa3d45b95bc85b84 311 Gene3D G3DSA:3.40.1190.20 6 298 3.1E-44 T 12-10-2018 IPR029056 Ribokinase-like UA74_15785 dd67931736148373fa3d45b95bc85b84 311 SUPERFAMILY SSF53613 18 297 3.05E-36 T 12-10-2018 IPR029056 Ribokinase-like UA74_12890 fa4de972cdb3a8c374ac226c61b32ffb 262 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 240 47.463 T 12-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 UA74_12890 fa4de972cdb3a8c374ac226c61b32ffb 262 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 236 2.5E-102 T 12-10-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 UA74_12890 fa4de972cdb3a8c374ac226c61b32ffb 262 SUPERFAMILY SSF56235 10 236 6.87E-38 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_12890 fa4de972cdb3a8c374ac226c61b32ffb 262 Pfam PF00227 Proteasome subunit 25 187 7.5E-28 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 UA74_12890 fa4de972cdb3a8c374ac226c61b32ffb 262 Gene3D G3DSA:3.60.20.10 1 249 3.9E-62 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_10875 8b28c74f59048f0db9c3330109ef39a3 471 Gene3D G3DSA:3.50.50.60 3 419 9.2E-128 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10875 8b28c74f59048f0db9c3330109ef39a3 471 SUPERFAMILY SSF51905 5 366 5.28E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10875 8b28c74f59048f0db9c3330109ef39a3 471 Pfam PF04820 Tryptophan halogenase 6 90 7.6E-13 T 12-10-2018 IPR006905 Flavin-dependent halogenase UA74_10875 8b28c74f59048f0db9c3330109ef39a3 471 Pfam PF04820 Tryptophan halogenase 97 385 4.5E-24 T 12-10-2018 IPR006905 Flavin-dependent halogenase UA74_10875 8b28c74f59048f0db9c3330109ef39a3 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 6.3E-8 T 12-10-2018 UA74_10875 8b28c74f59048f0db9c3330109ef39a3 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 6.3E-8 T 12-10-2018 UA74_10875 8b28c74f59048f0db9c3330109ef39a3 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 6.3E-8 T 12-10-2018 UA74_13230 51e02f8d85ea08504b60050e146dfda7 393 Pfam PF01032 FecCD transport family 81 383 2.7E-79 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_13230 51e02f8d85ea08504b60050e146dfda7 393 Gene3D G3DSA:1.10.3470.10 66 390 2.7E-86 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_13230 51e02f8d85ea08504b60050e146dfda7 393 SUPERFAMILY SSF81345 66 383 1.57E-69 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_21960 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.5E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_21960 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 Gene3D G3DSA:1.10.357.10 7 192 1.6E-43 T 12-10-2018 UA74_21960 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 SUPERFAMILY SSF48498 84 187 1.43E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_21960 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_21960 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_21960 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_21960 49b6eb4aab0f3b6c0ce3a2da17c0ca32 199 SUPERFAMILY SSF46689 6 89 4.99E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_23470 84d4bb3f5c2d592a5363dab4597a0a6a 500 Gene3D G3DSA:3.40.309.10 254 445 2.2E-107 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_23470 84d4bb3f5c2d592a5363dab4597a0a6a 500 Gene3D G3DSA:3.40.605.10 22 471 2.2E-107 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_23470 84d4bb3f5c2d592a5363dab4597a0a6a 500 Pfam PF00171 Aldehyde dehydrogenase family 23 472 3.7E-101 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_23470 84d4bb3f5c2d592a5363dab4597a0a6a 500 SUPERFAMILY SSF53720 22 476 8.9E-104 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 236 264 6.6E-26 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 287 307 6.6E-26 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 342 358 6.6E-26 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 214 229 6.6E-26 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 PRINTS PR00143 Citrate synthase signature 362 376 6.6E-26 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 Pfam PF12728 Helix-turn-helix domain 13 65 1.0E-8 T 12-10-2018 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 Gene3D G3DSA:1.10.580.10 89 382 1.3E-59 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 Pfam PF00285 Citrate synthase, C-terminal domain 76 391 3.2E-60 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 Gene3D G3DSA:1.10.230.10 262 356 1.3E-59 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 Gene3D G3DSA:1.10.1660.10 12 72 1.1E-6 T 12-10-2018 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 ProSitePatterns PS00480 Citrate synthase signature. 294 306 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 SUPERFAMILY SSF46955 12 64 1.46E-6 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_14140 0ddaad12cc5a519c52720337a9ea5639 403 SUPERFAMILY SSF48256 77 400 7.85E-66 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 UA74_27020 00485139a0d72fb66c8ca66f60bc267d 466 SUPERFAMILY SSF53187 71 449 6.65E-73 T 12-10-2018 UA74_27020 00485139a0d72fb66c8ca66f60bc267d 466 Gene3D G3DSA:3.30.70.360 244 358 9.2E-112 T 12-10-2018 UA74_27020 00485139a0d72fb66c8ca66f60bc267d 466 PIRSF PIRSF005962 71 452 8.3E-104 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 UA74_27020 00485139a0d72fb66c8ca66f60bc267d 466 SUPERFAMILY SSF55031 245 362 8.67E-21 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UA74_27020 00485139a0d72fb66c8ca66f60bc267d 466 Gene3D G3DSA:3.40.630.10 82 434 9.2E-112 T 12-10-2018 UA74_27020 00485139a0d72fb66c8ca66f60bc267d 466 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 83 437 9.6E-102 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 UA74_27020 00485139a0d72fb66c8ca66f60bc267d 466 Pfam PF01546 Peptidase family M20/M25/M40 137 445 4.1E-28 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 UA74_08130 c2d1012005e3ef762ac5096315f6f41b 455 Pfam PF08245 Mur ligase middle domain 54 280 1.5E-11 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UA74_08130 c2d1012005e3ef762ac5096315f6f41b 455 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 448 9.3E-96 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 UA74_08130 c2d1012005e3ef762ac5096315f6f41b 455 PIRSF PIRSF001563 5 455 5.9E-111 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 UA74_08130 c2d1012005e3ef762ac5096315f6f41b 455 Gene3D G3DSA:3.40.1190.10 8 308 1.4E-92 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_08130 c2d1012005e3ef762ac5096315f6f41b 455 SUPERFAMILY SSF53244 309 452 2.93E-24 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_08130 c2d1012005e3ef762ac5096315f6f41b 455 Gene3D G3DSA:3.90.190.20 309 455 2.7E-32 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_08130 c2d1012005e3ef762ac5096315f6f41b 455 SUPERFAMILY SSF53623 13 306 3.97E-86 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_08130 c2d1012005e3ef762ac5096315f6f41b 455 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 150 165 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 UA74_08130 c2d1012005e3ef762ac5096315f6f41b 455 Pfam PF02875 Mur ligase family, glutamate ligase domain 308 385 1.3E-8 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UA74_29905 17f891945d75bca446fb61078a6f7b54 276 Gene3D G3DSA:3.40.190.10 136 228 1.2E-53 T 12-10-2018 UA74_29905 17f891945d75bca446fb61078a6f7b54 276 SMART SM00062 50 272 3.8E-43 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_29905 17f891945d75bca446fb61078a6f7b54 276 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 71 84 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site UA74_29905 17f891945d75bca446fb61078a6f7b54 276 Gene3D G3DSA:3.40.190.10 56 270 1.2E-53 T 12-10-2018 UA74_29905 17f891945d75bca446fb61078a6f7b54 276 SUPERFAMILY SSF53850 9 270 1.06E-53 T 12-10-2018 UA74_29905 17f891945d75bca446fb61078a6f7b54 276 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 54 270 1.8E-51 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_20985 db24b0955cdb0f5cbfad02753e606e52 63 Pfam PF04149 Domain of unknown function (DUF397) 6 57 4.3E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_13570 475f6540236e52b00056c16821d19017 365 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 151 2.1E-25 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_13570 475f6540236e52b00056c16821d19017 365 Pfam PF00107 Zinc-binding dehydrogenase 193 315 5.9E-20 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_13570 475f6540236e52b00056c16821d19017 365 Gene3D G3DSA:3.40.50.720 170 306 6.8E-105 T 12-10-2018 UA74_13570 475f6540236e52b00056c16821d19017 365 SUPERFAMILY SSF50129 7 188 3.8E-47 T 12-10-2018 IPR011032 GroES-like superfamily UA74_13570 475f6540236e52b00056c16821d19017 365 SMART SM00829 12 361 1.0E-7 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_13570 475f6540236e52b00056c16821d19017 365 SUPERFAMILY SSF51735 155 329 2.76E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_13570 475f6540236e52b00056c16821d19017 365 Gene3D G3DSA:3.90.180.10 20 360 6.8E-105 T 12-10-2018 UA74_21055 38010d08bd6024199da79e5024f0bd48 607 SUPERFAMILY SSF52172 60 181 8.68E-22 T 12-10-2018 IPR011006 CheY-like superfamily UA74_21055 38010d08bd6024199da79e5024f0bd48 607 Gene3D G3DSA:3.40.50.12740 59 292 3.0E-24 T 12-10-2018 UA74_21055 38010d08bd6024199da79e5024f0bd48 607 Pfam PF00072 Response regulator receiver domain 61 173 3.2E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_21055 38010d08bd6024199da79e5024f0bd48 607 SMART SM00448 59 173 1.0E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_21055 38010d08bd6024199da79e5024f0bd48 607 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 410 590 3.5E-42 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_21055 38010d08bd6024199da79e5024f0bd48 607 SUPERFAMILY SSF81606 396 588 7.59E-9 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_21055 38010d08bd6024199da79e5024f0bd48 607 Gene3D G3DSA:3.60.40.10 375 591 1.6E-53 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_21055 38010d08bd6024199da79e5024f0bd48 607 SMART SM00331 380 590 3.5E-27 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_17530 80622057feb7da938ef2213350af6a43 513 SUPERFAMILY SSF103473 213 505 4.32E-20 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_17530 80622057feb7da938ef2213350af6a43 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 82 104 6.8E-5 T 12-10-2018 UA74_17530 80622057feb7da938ef2213350af6a43 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 6.8E-5 T 12-10-2018 UA74_17530 80622057feb7da938ef2213350af6a43 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 6.8E-5 T 12-10-2018 UA74_17530 80622057feb7da938ef2213350af6a43 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 22 46 6.8E-5 T 12-10-2018 UA74_17530 80622057feb7da938ef2213350af6a43 513 SUPERFAMILY SSF103473 8 200 1.07E-37 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_17530 80622057feb7da938ef2213350af6a43 513 Gene3D G3DSA:1.20.1720.10 20 225 2.5E-36 T 12-10-2018 UA74_17530 80622057feb7da938ef2213350af6a43 513 Pfam PF07690 Major Facilitator Superfamily 27 414 1.0E-36 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_08875 68690655e7001bbcafc13ecb76b73b02 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 326 5.7E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_08875 68690655e7001bbcafc13ecb76b73b02 329 Gene3D G3DSA:1.10.3720.10 93 321 5.6E-16 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08875 68690655e7001bbcafc13ecb76b73b02 329 SUPERFAMILY SSF161098 99 309 2.45E-13 T 12-10-2018 IPR035906 MetI-like superfamily UA74_07685 87e969a58d765df623046dca055c86ad 608 Gene3D G3DSA:3.40.50.620 196 379 1.0E-19 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_07685 87e969a58d765df623046dca055c86ad 608 SUPERFAMILY SSF52402 188 560 3.49E-25 T 12-10-2018 UA74_07685 87e969a58d765df623046dca055c86ad 608 Pfam PF00733 Asparagine synthase 207 591 1.5E-32 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 UA74_07685 87e969a58d765df623046dca055c86ad 608 Gene3D G3DSA:3.40.50.620 436 550 3.6E-5 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_03915 310d511f1bd3476ed67d87c0e9bd83bb 63 Pfam PF04149 Domain of unknown function (DUF397) 8 60 3.2E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_15405 e60a624e64bfdf7fef3743034faca2bb 205 Gene3D G3DSA:1.10.357.10 4 200 6.2E-22 T 12-10-2018 UA74_15405 e60a624e64bfdf7fef3743034faca2bb 205 SUPERFAMILY SSF46689 3 74 7.18E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_15405 e60a624e64bfdf7fef3743034faca2bb 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 7.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_01605 86da80bc169cc93a5e2bfbe3515e504a 261 Gene3D G3DSA:3.30.420.40 1 89 1.6E-20 T 12-10-2018 UA74_01605 86da80bc169cc93a5e2bfbe3515e504a 261 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 260 32.916 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_01605 86da80bc169cc93a5e2bfbe3515e504a 261 SUPERFAMILY SSF53067 2 124 2.96E-26 T 12-10-2018 UA74_01605 86da80bc169cc93a5e2bfbe3515e504a 261 Gene3D G3DSA:3.30.420.40 91 261 3.8E-52 T 12-10-2018 UA74_01605 86da80bc169cc93a5e2bfbe3515e504a 261 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 256 2.4E-70 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_01605 86da80bc169cc93a5e2bfbe3515e504a 261 Pfam PF03309 Type III pantothenate kinase 3 208 1.0E-60 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UA74_01605 86da80bc169cc93a5e2bfbe3515e504a 261 SUPERFAMILY SSF53067 126 259 5.44E-33 T 12-10-2018 UA74_11935 1c875f794e78d1cf33473dba4aeadabb 127 SMART SM00422 1 69 8.2E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_11935 1c875f794e78d1cf33473dba4aeadabb 127 SUPERFAMILY SSF46955 1 113 3.41E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_11935 1c875f794e78d1cf33473dba4aeadabb 127 Gene3D G3DSA:1.10.1660.10 1 122 1.7E-26 T 12-10-2018 UA74_11935 1c875f794e78d1cf33473dba4aeadabb 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_11935 1c875f794e78d1cf33473dba4aeadabb 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_11935 1c875f794e78d1cf33473dba4aeadabb 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_11935 1c875f794e78d1cf33473dba4aeadabb 127 Pfam PF13411 MerR HTH family regulatory protein 1 64 4.4E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_08100 202fa4c1829d326467faebc9d16516c4 292 SUPERFAMILY SSF53927 4 272 1.02E-78 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UA74_08100 202fa4c1829d326467faebc9d16516c4 292 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 272 8.3E-52 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 UA74_08100 202fa4c1829d326467faebc9d16516c4 292 PIRSF PIRSF015626 1 276 2.5E-87 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 UA74_08100 202fa4c1829d326467faebc9d16516c4 292 Pfam PF02634 FdhD/NarQ family 26 272 2.0E-83 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 UA74_08100 202fa4c1829d326467faebc9d16516c4 292 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 273 34.679 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 UA74_08100 202fa4c1829d326467faebc9d16516c4 292 Gene3D G3DSA:3.40.140.10 125 281 2.4E-54 T 12-10-2018 UA74_08100 202fa4c1829d326467faebc9d16516c4 292 Gene3D G3DSA:3.10.20.10 28 120 3.4E-6 T 12-10-2018 UA74_14260 5bec1e0ddbcdeb2bf414cec089486c7e 220 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 23 217 1.0E-33 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal UA74_14260 5bec1e0ddbcdeb2bf414cec089486c7e 220 SUPERFAMILY SSF81296 23 219 9.1E-32 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_14260 5bec1e0ddbcdeb2bf414cec089486c7e 220 Gene3D G3DSA:2.70.50.50 23 219 2.7E-61 T 12-10-2018 UA74_22010 221028ef198b4dfa87eea0c55a833a8a 163 SUPERFAMILY SSF56349 13 116 7.65E-15 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_22010 221028ef198b4dfa87eea0c55a833a8a 163 Gene3D G3DSA:1.10.443.10 3 122 5.1E-16 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_22010 221028ef198b4dfa87eea0c55a833a8a 163 Pfam PF00589 Phage integrase family 7 109 4.9E-7 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_29900 5719d1a80982dd947e330fb56b291bb9 327 SMART SM00079 72 290 1.9E-4 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 UA74_29900 5719d1a80982dd947e330fb56b291bb9 327 SMART SM00062 72 291 2.1E-57 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_29900 5719d1a80982dd947e330fb56b291bb9 327 SUPERFAMILY SSF53850 32 289 4.36E-63 T 12-10-2018 UA74_29900 5719d1a80982dd947e330fb56b291bb9 327 Gene3D G3DSA:3.40.190.10 158 250 3.7E-63 T 12-10-2018 UA74_29900 5719d1a80982dd947e330fb56b291bb9 327 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 94 107 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site UA74_29900 5719d1a80982dd947e330fb56b291bb9 327 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 74 289 1.1E-58 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_29900 5719d1a80982dd947e330fb56b291bb9 327 Gene3D G3DSA:3.40.190.10 77 288 3.7E-63 T 12-10-2018 UA74_04005 7e5c1e67660b3369f2e25255125ba7bc 398 PIRSF PIRSF009283 25 398 3.3E-130 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 UA74_04005 7e5c1e67660b3369f2e25255125ba7bc 398 Gene3D G3DSA:3.10.180.10 194 398 2.9E-77 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_04005 7e5c1e67660b3369f2e25255125ba7bc 398 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 38 398 1.7E-126 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 UA74_04005 7e5c1e67660b3369f2e25255125ba7bc 398 SUPERFAMILY SSF54593 30 385 5.65E-89 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_04005 7e5c1e67660b3369f2e25255125ba7bc 398 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 209 352 8.5E-15 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_04005 7e5c1e67660b3369f2e25255125ba7bc 398 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 40 149 8.5E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_04005 7e5c1e67660b3369f2e25255125ba7bc 398 Gene3D G3DSA:3.10.180.10 24 191 7.6E-49 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_01985 5addc70afd1ec3755eba57e2196958a0 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 269 8.0E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_01985 5addc70afd1ec3755eba57e2196958a0 276 SUPERFAMILY SSF161098 2 276 2.43E-78 T 12-10-2018 IPR035906 MetI-like superfamily UA74_01985 5addc70afd1ec3755eba57e2196958a0 276 Gene3D G3DSA:1.10.3720.10 1 267 4.0E-69 T 12-10-2018 IPR035906 MetI-like superfamily UA74_17985 ef9d31c3f3aff7fab1c5a24204047ff1 351 SUPERFAMILY SSF50129 4 111 8.48E-18 T 12-10-2018 IPR011032 GroES-like superfamily UA74_17985 ef9d31c3f3aff7fab1c5a24204047ff1 351 Pfam PF16884 N-terminal domain of oxidoreductase 5 102 3.6E-14 T 12-10-2018 UA74_17985 ef9d31c3f3aff7fab1c5a24204047ff1 351 Gene3D G3DSA:3.40.50.720 138 318 2.5E-80 T 12-10-2018 UA74_17985 ef9d31c3f3aff7fab1c5a24204047ff1 351 Pfam PF00107 Zinc-binding dehydrogenase 170 293 1.2E-14 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_17985 ef9d31c3f3aff7fab1c5a24204047ff1 351 Gene3D G3DSA:3.90.180.10 23 349 2.5E-80 T 12-10-2018 UA74_17985 ef9d31c3f3aff7fab1c5a24204047ff1 351 SMART SM00829 14 349 6.4E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_17985 ef9d31c3f3aff7fab1c5a24204047ff1 351 SUPERFAMILY SSF51735 136 305 1.32E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25950 1412abf636ac0b7f8eca57ef78168eed 614 Pfam PF00920 Dehydratase family 34 608 1.3E-210 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_25950 1412abf636ac0b7f8eca57ef78168eed 614 Gene3D G3DSA:3.50.30.80 423 574 3.4E-55 T 12-10-2018 UA74_25950 1412abf636ac0b7f8eca57ef78168eed 614 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 611 1.8E-232 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_25950 1412abf636ac0b7f8eca57ef78168eed 614 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_25950 1412abf636ac0b7f8eca57ef78168eed 614 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 611 44.388 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_25950 1412abf636ac0b7f8eca57ef78168eed 614 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_25950 1412abf636ac0b7f8eca57ef78168eed 614 SUPERFAMILY SSF52016 423 612 3.3E-59 T 12-10-2018 UA74_25950 1412abf636ac0b7f8eca57ef78168eed 614 SUPERFAMILY SSF143975 4 422 4.05E-131 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_19700 ec4b514a312a0a21a8bd75f34800e1ff 245 ProSitePatterns PS00552 MerR-type HTH domain signature. 121 143 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_19700 ec4b514a312a0a21a8bd75f34800e1ff 245 SMART SM00422 1 69 0.011 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_19700 ec4b514a312a0a21a8bd75f34800e1ff 245 SMART SM00422 118 187 1.4E-10 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_19700 ec4b514a312a0a21a8bd75f34800e1ff 245 Pfam PF00376 MerR family regulatory protein 5 39 1.2E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_19700 ec4b514a312a0a21a8bd75f34800e1ff 245 Gene3D G3DSA:1.10.1660.10 5 113 6.8E-13 T 12-10-2018 UA74_19700 ec4b514a312a0a21a8bd75f34800e1ff 245 SUPERFAMILY SSF46955 118 230 2.01E-18 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_19700 ec4b514a312a0a21a8bd75f34800e1ff 245 Pfam PF13411 MerR HTH family regulatory protein 119 186 4.2E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_19700 ec4b514a312a0a21a8bd75f34800e1ff 245 Gene3D G3DSA:1.10.1660.10 114 240 7.1E-22 T 12-10-2018 UA74_19700 ec4b514a312a0a21a8bd75f34800e1ff 245 SUPERFAMILY SSF46955 5 107 3.48E-13 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 Pfam PF00406 Adenylate kinase 5 159 8.1E-51 T 12-10-2018 UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 4 17 3.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 32 46 3.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 81 97 3.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 130 145 3.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 PRINTS PR00094 Adenylate kinase signature 147 161 3.9E-31 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 SUPERFAMILY SSF52540 2 180 1.78E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 Hamap MF_00235 Adenylate kinase [adk]. 1 181 41.574 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UA74_03100 c48c43a48948ffd20b161ed194e3a27c 186 Gene3D G3DSA:3.40.50.300 1 181 3.9E-61 T 12-10-2018 UA74_16855 7ab0f0a69267fd75e1695db0297a2d43 363 SUPERFAMILY SSF53335 120 356 2.51E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_16855 7ab0f0a69267fd75e1695db0297a2d43 363 Pfam PF00891 O-methyltransferase 130 341 1.5E-46 T 12-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_16855 7ab0f0a69267fd75e1695db0297a2d43 363 PIRSF PIRSF005739 12 359 9.3E-44 T 12-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_16855 7ab0f0a69267fd75e1695db0297a2d43 363 Gene3D G3DSA:3.40.50.150 120 358 1.9E-61 T 12-10-2018 UA74_16855 7ab0f0a69267fd75e1695db0297a2d43 363 SUPERFAMILY SSF46785 33 112 4.5E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_16855 7ab0f0a69267fd75e1695db0297a2d43 363 Gene3D G3DSA:1.10.10.10 26 119 8.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18305 5a95780e7247ed7eeea98bcc634c1584 153 Gene3D G3DSA:3.30.530.20 5 147 8.4E-20 T 12-10-2018 IPR023393 START-like domain superfamily UA74_18305 5a95780e7247ed7eeea98bcc634c1584 153 SUPERFAMILY SSF55961 17 146 9.47E-18 T 12-10-2018 UA74_18305 5a95780e7247ed7eeea98bcc634c1584 153 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 16 146 5.0E-12 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase UA74_20465 03874e0e457876a92a3c522a72c92322 207 SUPERFAMILY SSF54719 86 196 4.58E-40 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 Gene3D G3DSA:1.10.287.990 21 84 2.1E-22 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 3.5E-26 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 PIRSF PIRSF000349 1 200 5.8E-65 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 SUPERFAMILY SSF46609 3 88 4.06E-26 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 Gene3D G3DSA:2.40.500.20 85 204 3.4E-40 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 5.0E-18 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 156 168 5.0E-18 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 5.0E-18 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 5.0E-18 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 5.0E-18 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 191 5.4E-32 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_20465 03874e0e457876a92a3c522a72c92322 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 158 165 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UA74_00920 c8d3c225b1e79d3ff999b6d5ef9746ac 414 SUPERFAMILY SSF142764 10 405 2.48E-45 T 12-10-2018 UA74_00920 c8d3c225b1e79d3ff999b6d5ef9746ac 414 Pfam PF07005 Putative sugar-binding N-terminal domain 10 222 5.1E-17 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain UA74_00920 c8d3c225b1e79d3ff999b6d5ef9746ac 414 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 253 398 9.7E-19 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain UA74_00920 c8d3c225b1e79d3ff999b6d5ef9746ac 414 Gene3D G3DSA:3.40.50.10840 8 231 1.1E-20 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily UA74_00920 c8d3c225b1e79d3ff999b6d5ef9746ac 414 Gene3D G3DSA:3.40.980.20 242 407 1.6E-17 T 12-10-2018 UA74_07075 8238197a3ac52a424e4eda9a71ee0482 188 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 162 1.1E-48 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_07075 8238197a3ac52a424e4eda9a71ee0482 188 Gene3D G3DSA:1.10.10.10 81 166 1.7E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_07075 8238197a3ac52a424e4eda9a71ee0482 188 Pfam PF04542 Sigma-70 region 2 17 77 1.6E-6 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_07075 8238197a3ac52a424e4eda9a71ee0482 188 SUPERFAMILY SSF88946 5 90 7.85E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_07075 8238197a3ac52a424e4eda9a71ee0482 188 Pfam PF08281 Sigma-70, region 4 103 156 4.7E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_07075 8238197a3ac52a424e4eda9a71ee0482 188 Gene3D G3DSA:1.10.1740.10 2 79 5.0E-6 T 12-10-2018 UA74_07075 8238197a3ac52a424e4eda9a71ee0482 188 SUPERFAMILY SSF88659 102 159 8.04E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_07075 8238197a3ac52a424e4eda9a71ee0482 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 158 1.3E-18 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_10965 4b641f3974c6f550405f651d92078aa2 221 Gene3D G3DSA:1.20.910.10 1 221 7.0E-40 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_10965 4b641f3974c6f550405f651d92078aa2 221 SUPERFAMILY SSF48613 1 220 1.11E-34 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_10965 4b641f3974c6f550405f651d92078aa2 221 Pfam PF03070 TENA/THI-4/PQQC family 17 210 4.0E-17 T 12-10-2018 IPR004305 Thiaminase-2/PQQC UA74_23375 9c2d79ccce0709f51bd98d6985e7e6fe 279 SUPERFAMILY SSF46689 30 93 2.36E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_23375 9c2d79ccce0709f51bd98d6985e7e6fe 279 Gene3D G3DSA:1.10.10.60 10 90 2.8E-25 T 12-10-2018 UA74_23375 9c2d79ccce0709f51bd98d6985e7e6fe 279 SUPERFAMILY SSF48498 106 272 1.56E-20 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_23375 9c2d79ccce0709f51bd98d6985e7e6fe 279 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 84 4.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_23375 9c2d79ccce0709f51bd98d6985e7e6fe 279 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 100 206 1.1E-12 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_23375 9c2d79ccce0709f51bd98d6985e7e6fe 279 Gene3D G3DSA:1.10.357.10 99 278 2.6E-31 T 12-10-2018 UA74_16990 32b3f99735970a2879636e0d9df055c5 305 Pfam PF00701 Dihydrodipicolinate synthetase family 8 294 1.8E-43 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_16990 32b3f99735970a2879636e0d9df055c5 305 Gene3D G3DSA:3.20.20.70 2 299 8.3E-77 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_16990 32b3f99735970a2879636e0d9df055c5 305 SMART SM01130 7 299 4.5E-82 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_16990 32b3f99735970a2879636e0d9df055c5 305 PIRSF PIRSF001365 3 304 6.7E-66 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_16990 32b3f99735970a2879636e0d9df055c5 305 SUPERFAMILY SSF51569 4 297 7.01E-74 T 12-10-2018 UA74_16990 32b3f99735970a2879636e0d9df055c5 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 47 68 2.2E-6 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_16990 32b3f99735970a2879636e0d9df055c5 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 115 131 2.2E-6 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_16990 32b3f99735970a2879636e0d9df055c5 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 2.2E-6 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 2.3E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 2.3E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 SMART SM00345 8 67 2.1E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 8.1E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 SMART SM00895 96 213 1.5E-16 T 12-10-2018 IPR011711 GntR, C-terminal UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 Pfam PF07729 FCD domain 96 211 1.5E-22 T 12-10-2018 IPR011711 GntR, C-terminal UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 Gene3D G3DSA:1.20.120.530 94 228 2.7E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 SUPERFAMILY SSF46785 7 71 8.33E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 SUPERFAMILY SSF48008 94 221 6.28E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_10105 32d3492c70a2552fb05dbd3e0e087ca4 229 Gene3D G3DSA:1.10.10.10 5 73 4.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28075 c94881622754354f7b36e3ead38f5958 477 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 352 362 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_28075 c94881622754354f7b36e3ead38f5958 477 Gene3D G3DSA:3.40.50.200 54 415 2.4E-88 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_28075 c94881622754354f7b36e3ead38f5958 477 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 100 472 5.6E-111 T 12-10-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin UA74_28075 c94881622754354f7b36e3ead38f5958 477 SUPERFAMILY SSF52743 92 412 6.28E-72 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_28075 c94881622754354f7b36e3ead38f5958 477 PRINTS PR00723 Subtilisin serine protease family (S8) signature 351 367 2.4E-13 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_28075 c94881622754354f7b36e3ead38f5958 477 PRINTS PR00723 Subtilisin serine protease family (S8) signature 111 130 2.4E-13 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_28075 c94881622754354f7b36e3ead38f5958 477 PRINTS PR00723 Subtilisin serine protease family (S8) signature 148 161 2.4E-13 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_28075 c94881622754354f7b36e3ead38f5958 477 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 152 162 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UA74_28075 c94881622754354f7b36e3ead38f5958 477 Pfam PF00082 Subtilase family 113 401 4.8E-40 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_28075 c94881622754354f7b36e3ead38f5958 477 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 116 126 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_21695 42cb9d0e4d5b9457e418b5cc56de87fb 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.2E-14 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_21695 42cb9d0e4d5b9457e418b5cc56de87fb 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.2E-14 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_21695 42cb9d0e4d5b9457e418b5cc56de87fb 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.2E-14 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_21695 42cb9d0e4d5b9457e418b5cc56de87fb 64 Pfam PF01632 Ribosomal protein L35 2 62 5.1E-24 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21695 42cb9d0e4d5b9457e418b5cc56de87fb 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 16.821 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_21695 42cb9d0e4d5b9457e418b5cc56de87fb 64 SUPERFAMILY SSF143034 2 63 7.72E-21 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21695 42cb9d0e4d5b9457e418b5cc56de87fb 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21695 42cb9d0e4d5b9457e418b5cc56de87fb 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 1.7E-22 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UA74_21695 42cb9d0e4d5b9457e418b5cc56de87fb 64 Gene3D G3DSA:2.40.50.530 1 63 7.0E-24 T 12-10-2018 UA74_14335 a2019eaa7506e24a3fcd3b19e9310a1a 116 Pfam PF14534 Domain of unknown function (DUF4440) 14 101 9.0E-8 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 UA74_14335 a2019eaa7506e24a3fcd3b19e9310a1a 116 Gene3D G3DSA:3.10.450.50 7 115 1.5E-5 T 12-10-2018 UA74_14335 a2019eaa7506e24a3fcd3b19e9310a1a 116 SUPERFAMILY SSF54427 7 115 2.57E-9 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_25285 9c9704786bc1e529b49f65c16241c270 330 Pfam PF03186 CobD/Cbib protein 9 290 8.9E-90 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UA74_25285 9c9704786bc1e529b49f65c16241c270 330 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 9 267 3.8E-52 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UA74_25285 9c9704786bc1e529b49f65c16241c270 330 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 312 92.453 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UA74_09255 58d7465e0b267c646e9a52e8227639af 190 Pfam PF02033 Ribosome-binding factor A 6 113 9.3E-25 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 UA74_09255 58d7465e0b267c646e9a52e8227639af 190 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 5 114 3.6E-19 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 UA74_09255 58d7465e0b267c646e9a52e8227639af 190 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 5 113 23.059 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 UA74_09255 58d7465e0b267c646e9a52e8227639af 190 Gene3D G3DSA:3.30.300.20 2 106 2.6E-24 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_09255 58d7465e0b267c646e9a52e8227639af 190 SUPERFAMILY SSF89919 3 116 7.59E-26 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily UA74_09255 58d7465e0b267c646e9a52e8227639af 190 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 12-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 UA74_09255 58d7465e0b267c646e9a52e8227639af 190 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 8.0E-25 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 UA74_14825 a750bb47fe62dfc23cac95df87ad4262 314 SUPERFAMILY SSF53335 167 271 5.94E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_14825 a750bb47fe62dfc23cac95df87ad4262 314 Pfam PF13649 Methyltransferase domain 174 263 6.4E-9 T 12-10-2018 UA74_14825 a750bb47fe62dfc23cac95df87ad4262 314 Gene3D G3DSA:3.40.50.150 100 297 1.3E-17 T 12-10-2018 UA74_21780 da25e10683da6e6ab75738fa9738f968 681 SUPERFAMILY SSF140459 49 203 1.02E-12 T 12-10-2018 UA74_21780 da25e10683da6e6ab75738fa9738f968 681 Gene3D G3DSA:1.20.1260.20 44 205 1.4E-11 T 12-10-2018 IPR038332 PPE superfamily UA74_21780 da25e10683da6e6ab75738fa9738f968 681 Pfam PF00823 PPE family 59 189 2.3E-10 T 12-10-2018 IPR000030 PPE family UA74_22685 8df55aaa868508682c69151cbf0925dc 367 SUPERFAMILY SSF55961 14 156 1.45E-36 T 12-10-2018 UA74_22685 8df55aaa868508682c69151cbf0925dc 367 Gene3D G3DSA:3.40.430.10 165 365 1.0E-41 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_22685 8df55aaa868508682c69151cbf0925dc 367 SUPERFAMILY SSF53597 170 364 1.83E-25 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_22685 8df55aaa868508682c69151cbf0925dc 367 Gene3D G3DSA:3.30.530.20 1 159 8.3E-41 T 12-10-2018 IPR023393 START-like domain superfamily UA74_22685 8df55aaa868508682c69151cbf0925dc 367 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 25 156 1.1E-18 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_22685 8df55aaa868508682c69151cbf0925dc 367 Pfam PF01872 RibD C-terminal domain 170 356 9.2E-21 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 Pfam PF00067 Cytochrome P450 274 372 3.5E-17 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00385 P450 superfamily signature 343 352 6.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00385 P450 superfamily signature 241 258 6.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00385 P450 superfamily signature 352 363 6.4E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 SUPERFAMILY SSF48264 16 403 4.71E-91 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 Gene3D G3DSA:1.10.630.10 7 403 4.2E-123 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00463 E-class P450 group I signature 342 352 1.7E-7 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00463 E-class P450 group I signature 230 247 1.7E-7 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00463 E-class P450 group I signature 275 293 1.7E-7 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 PRINTS PR00463 E-class P450 group I signature 352 375 1.7E-7 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_18170 1c618676ca8bb047c8dc418743b72d0e 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_11970 7a5cc4cd6d7914774034b1d81dd5c1b8 169 SUPERFAMILY SSF46785 5 148 7.65E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_11970 7a5cc4cd6d7914774034b1d81dd5c1b8 169 Pfam PF01047 MarR family 47 97 9.0E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_11970 7a5cc4cd6d7914774034b1d81dd5c1b8 169 Gene3D G3DSA:1.10.10.10 6 161 2.3E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_11970 7a5cc4cd6d7914774034b1d81dd5c1b8 169 SMART SM00347 32 135 3.0E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_12585 ac1b14664dc6228ff27a3725cfb0a675 314 SUPERFAMILY SSF53474 49 306 3.94E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_12585 ac1b14664dc6228ff27a3725cfb0a675 314 Pfam PF07859 alpha/beta hydrolase fold 78 283 7.0E-64 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 UA74_12585 ac1b14664dc6228ff27a3725cfb0a675 314 Gene3D G3DSA:3.40.50.1820 3 310 5.2E-90 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07330 ad073cd703f3f6ba2414f684d8e7ef89 661 Gene3D G3DSA:3.20.20.80 220 571 4.2E-103 T 12-10-2018 UA74_07330 ad073cd703f3f6ba2414f684d8e7ef89 661 SUPERFAMILY SSF51445 209 571 2.0E-64 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07330 ad073cd703f3f6ba2414f684d8e7ef89 661 SUPERFAMILY SSF74650 6 207 2.39E-29 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 UA74_07330 ad073cd703f3f6ba2414f684d8e7ef89 661 SUPERFAMILY SSF51011 572 652 1.15E-23 T 12-10-2018 UA74_07330 ad073cd703f3f6ba2414f684d8e7ef89 661 Gene3D G3DSA:2.60.40.1760 3 219 1.3E-44 T 12-10-2018 UA74_07330 ad073cd703f3f6ba2414f684d8e7ef89 661 Pfam PF01055 Glycosyl hydrolases family 31 202 655 7.4E-119 T 12-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 UA74_07330 ad073cd703f3f6ba2414f684d8e7ef89 661 Gene3D G3DSA:2.60.40.1180 574 652 7.7E-28 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_05140 0d829dc5192fa8a15647d064d0f86616 588 Gene3D G3DSA:3.40.50.12780 2 399 2.3E-85 T 12-10-2018 UA74_05140 0d829dc5192fa8a15647d064d0f86616 588 Pfam PF00550 Phosphopantetheine attachment site 522 584 1.0E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_05140 0d829dc5192fa8a15647d064d0f86616 588 Gene3D G3DSA:1.10.1200.10 507 587 1.0E-13 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05140 0d829dc5192fa8a15647d064d0f86616 588 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 489 3.2E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_05140 0d829dc5192fa8a15647d064d0f86616 588 Pfam PF00501 AMP-binding enzyme 13 405 1.5E-59 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_05140 0d829dc5192fa8a15647d064d0f86616 588 ProSitePatterns PS00012 Phosphopantetheine attachment site. 543 558 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site UA74_05140 0d829dc5192fa8a15647d064d0f86616 588 Gene3D G3DSA:3.30.300.30 400 506 1.2E-24 T 12-10-2018 UA74_05140 0d829dc5192fa8a15647d064d0f86616 588 SUPERFAMILY SSF56801 6 528 9.29E-102 T 12-10-2018 UA74_05140 0d829dc5192fa8a15647d064d0f86616 588 SUPERFAMILY SSF47336 516 586 7.33E-12 T 12-10-2018 IPR036736 ACP-like superfamily UA74_20730 aa563ddd2b96780f0c8f0f5a06b129e7 245 Pfam PF09684 Phage tail protein (Tail_P2_I) 32 166 1.2E-13 T 12-10-2018 IPR006521 Tail protein I UA74_20730 aa563ddd2b96780f0c8f0f5a06b129e7 245 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 17 119 3.1E-28 T 12-10-2018 IPR011748 Uncharacterised protein family, phage tail-like UA74_02710 caf3717f77eed2fef0238e0907a8989b 610 Gene3D G3DSA:3.90.220.20 463 599 1.2E-5 T 12-10-2018 UA74_02710 caf3717f77eed2fef0238e0907a8989b 610 SUPERFAMILY SSF116734 449 596 4.41E-8 T 12-10-2018 UA74_02710 caf3717f77eed2fef0238e0907a8989b 610 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 274 298 6.5E-10 T 12-10-2018 UA74_02710 caf3717f77eed2fef0238e0907a8989b 610 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 240 252 6.5E-10 T 12-10-2018 UA74_02710 caf3717f77eed2fef0238e0907a8989b 610 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 176 190 6.5E-10 T 12-10-2018 UA74_02710 caf3717f77eed2fef0238e0907a8989b 610 SUPERFAMILY SSF53335 131 343 3.93E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_02710 caf3717f77eed2fef0238e0907a8989b 610 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 243 249 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_02710 caf3717f77eed2fef0238e0907a8989b 610 Pfam PF02384 N-6 DNA Methylase 133 329 8.2E-25 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_02710 caf3717f77eed2fef0238e0907a8989b 610 Gene3D G3DSA:3.40.50.150 135 356 4.8E-35 T 12-10-2018 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 377 386 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 Pfam PF00067 Cytochrome P450 18 411 1.3E-63 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 Gene3D G3DSA:1.10.630.10 7 434 9.2E-99 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00385 P450 superfamily signature 375 384 6.5E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00385 P450 superfamily signature 298 309 6.5E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00385 P450 superfamily signature 384 395 6.5E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00385 P450 superfamily signature 246 263 6.5E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 SUPERFAMILY SSF48264 13 435 4.45E-92 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 374 384 1.1E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 235 252 1.1E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 384 407 1.1E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 337 361 1.1E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 255 281 1.1E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24090 54608386d84ef399fd0c9f5802c921b1 436 PRINTS PR00463 E-class P450 group I signature 24 43 1.1E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24745 76ef5b03baf5043c77bcd5c79966fed9 282 SMART SM00530 16 72 1.6E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_24745 76ef5b03baf5043c77bcd5c79966fed9 282 Gene3D G3DSA:1.10.260.40 6 73 7.2E-11 T 12-10-2018 UA74_24745 76ef5b03baf5043c77bcd5c79966fed9 282 SUPERFAMILY SSF47413 19 71 9.12E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_24745 76ef5b03baf5043c77bcd5c79966fed9 282 Pfam PF13560 Helix-turn-helix domain 13 74 6.7E-10 T 12-10-2018 UA74_29785 8495385c7fec8e54084e85e143443fbc 233 Gene3D G3DSA:3.40.50.1000 26 218 2.0E-52 T 12-10-2018 IPR023214 HAD superfamily UA74_29785 8495385c7fec8e54084e85e143443fbc 233 Gene3D G3DSA:1.10.150.240 40 98 2.0E-52 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_29785 8495385c7fec8e54084e85e143443fbc 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 28 197 6.8E-25 T 12-10-2018 UA74_29785 8495385c7fec8e54084e85e143443fbc 233 SUPERFAMILY SSF56784 26 218 1.35E-44 T 12-10-2018 IPR036412 HAD-like superfamily UA74_29785 8495385c7fec8e54084e85e143443fbc 233 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 27 191 1.1E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_29785 8495385c7fec8e54084e85e143443fbc 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 159 179 1.9E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_29785 8495385c7fec8e54084e85e143443fbc 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 25 36 1.9E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_29785 8495385c7fec8e54084e85e143443fbc 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 1.9E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_29785 8495385c7fec8e54084e85e143443fbc 233 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 27 197 8.3E-20 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_09750 47ff7e04fecd29de4d1a72331724728c 212 SUPERFAMILY SSF46689 16 93 4.82E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_09750 47ff7e04fecd29de4d1a72331724728c 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 2.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_09750 47ff7e04fecd29de4d1a72331724728c 212 Gene3D G3DSA:1.10.357.10 67 207 1.8E-18 T 12-10-2018 UA74_09750 47ff7e04fecd29de4d1a72331724728c 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_09750 47ff7e04fecd29de4d1a72331724728c 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_09750 47ff7e04fecd29de4d1a72331724728c 212 Gene3D G3DSA:1.10.10.60 6 66 7.5E-15 T 12-10-2018 UA74_09750 47ff7e04fecd29de4d1a72331724728c 212 SUPERFAMILY SSF48498 93 199 4.2E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_27315 9c2215b1ac8f6e8554710073885ab021 190 Gene3D G3DSA:1.10.10.10 56 190 1.9E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27315 9c2215b1ac8f6e8554710073885ab021 190 SUPERFAMILY SSF46785 60 189 2.24E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04375 9342c07cc1572b254a72418255ae56f8 331 SUPERFAMILY SSF161098 93 317 2.13E-17 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04375 9342c07cc1572b254a72418255ae56f8 331 Gene3D G3DSA:1.10.3720.10 88 322 8.8E-21 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04375 9342c07cc1572b254a72418255ae56f8 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 329 3.9E-40 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 186 259 3.2E-21 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 SUPERFAMILY SSF48168 45 261 4.36E-58 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 Pfam PF02867 Ribonucleotide reductase, barrel domain 263 803 1.3E-179 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 190 806 2.9E-207 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 647 669 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 Pfam PF03477 ATP cone domain 40 124 1.5E-4 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 484 9.8E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 PRINTS PR01183 Ribonucleotide reductase large chain signature 338 357 9.8E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 PRINTS PR01183 Ribonucleotide reductase large chain signature 515 538 9.8E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 PRINTS PR01183 Ribonucleotide reductase large chain signature 658 685 9.8E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 PRINTS PR01183 Ribonucleotide reductase large chain signature 553 575 9.8E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 PRINTS PR01183 Ribonucleotide reductase large chain signature 581 604 9.8E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 Gene3D G3DSA:3.20.70.20 113 814 8.7E-241 T 12-10-2018 UA74_11265 d063bef8f573dd5b4a948b0c0094980e 862 SUPERFAMILY SSF51998 262 808 2.01E-175 T 12-10-2018 UA74_14810 0a4b3ac75745b6e3c0375c7a7f2fea71 349 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 13 344 5.5E-102 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 UA74_14810 0a4b3ac75745b6e3c0375c7a7f2fea71 349 SUPERFAMILY SSF54593 12 337 7.97E-68 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_14810 0a4b3ac75745b6e3c0375c7a7f2fea71 349 Gene3D G3DSA:3.10.180.10 153 348 1.9E-62 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_14810 0a4b3ac75745b6e3c0375c7a7f2fea71 349 PIRSF PIRSF009283 1 349 1.7E-106 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 UA74_14810 0a4b3ac75745b6e3c0375c7a7f2fea71 349 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 46 136 2.5E-9 T 12-10-2018 UA74_14810 0a4b3ac75745b6e3c0375c7a7f2fea71 349 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 157 271 3.5E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_14810 0a4b3ac75745b6e3c0375c7a7f2fea71 349 Gene3D G3DSA:3.10.180.10 8 152 1.1E-34 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_01115 9b6c43f8bb66ea0583460113ef8194bb 186 SUPERFAMILY SSF52218 4 177 2.35E-33 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_01115 9b6c43f8bb66ea0583460113ef8194bb 186 Pfam PF03358 NADPH-dependent FMN reductase 4 143 8.7E-23 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_01115 9b6c43f8bb66ea0583460113ef8194bb 186 Gene3D G3DSA:3.40.50.360 1 186 1.1E-40 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_25555 c3cafca704eadc625a0ddb01120421e3 225 Pfam PF00072 Response regulator receiver domain 4 112 1.9E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_25555 c3cafca704eadc625a0ddb01120421e3 225 SMART SM00448 2 112 1.6E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_25555 c3cafca704eadc625a0ddb01120421e3 225 Gene3D G3DSA:3.40.50.2300 1 124 9.6E-35 T 12-10-2018 UA74_25555 c3cafca704eadc625a0ddb01120421e3 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 3.6E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_25555 c3cafca704eadc625a0ddb01120421e3 225 Gene3D G3DSA:1.10.10.10 125 225 6.7E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_25555 c3cafca704eadc625a0ddb01120421e3 225 SMART SM00862 147 223 8.4E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_25555 c3cafca704eadc625a0ddb01120421e3 225 SUPERFAMILY SSF52172 1 181 2.13E-40 T 12-10-2018 IPR011006 CheY-like superfamily UA74_08690 499116f951a12e5bc703639e9a980125 324 Gene3D G3DSA:1.10.10.10 30 105 1.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08690 499116f951a12e5bc703639e9a980125 324 Pfam PF00392 Bacterial regulatory proteins, gntR family 44 103 9.4E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_08690 499116f951a12e5bc703639e9a980125 324 SMART SM00866 127 264 6.6E-27 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_08690 499116f951a12e5bc703639e9a980125 324 Gene3D G3DSA:3.40.1410.10 112 277 7.4E-36 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_08690 499116f951a12e5bc703639e9a980125 324 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 79 95 1.6E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_08690 499116f951a12e5bc703639e9a980125 324 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 65 79 1.6E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_08690 499116f951a12e5bc703639e9a980125 324 SUPERFAMILY SSF64288 93 270 2.83E-38 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_08690 499116f951a12e5bc703639e9a980125 324 SUPERFAMILY SSF46785 35 118 2.22E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_08690 499116f951a12e5bc703639e9a980125 324 SMART SM00345 46 105 1.8E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_08690 499116f951a12e5bc703639e9a980125 324 Pfam PF07702 UTRA domain 128 263 1.2E-30 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_29985 a87c5fbf9703de8d55ce2b203b5408d4 558 Pfam PF09594 Glycosyltransferase family 87 197 422 2.4E-15 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 UA74_29985 a87c5fbf9703de8d55ce2b203b5408d4 558 PIRSF PIRSF010361 47 526 1.7E-168 T 12-10-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane UA74_17170 2a29072cc5219280e31b36de7bd869d0 205 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 40 196 1.0E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_17170 2a29072cc5219280e31b36de7bd869d0 205 SUPERFAMILY SSF88659 139 196 1.42E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_17170 2a29072cc5219280e31b36de7bd869d0 205 Gene3D G3DSA:1.10.1740.10 18 106 7.4E-31 T 12-10-2018 UA74_17170 2a29072cc5219280e31b36de7bd869d0 205 Pfam PF04542 Sigma-70 region 2 45 109 1.9E-12 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_17170 2a29072cc5219280e31b36de7bd869d0 205 Pfam PF08281 Sigma-70, region 4 144 193 4.5E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_17170 2a29072cc5219280e31b36de7bd869d0 205 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 65 96 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_17170 2a29072cc5219280e31b36de7bd869d0 205 SUPERFAMILY SSF88946 20 123 3.18E-22 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_17170 2a29072cc5219280e31b36de7bd869d0 205 Gene3D G3DSA:1.10.10.10 136 202 2.4E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16940 c1247e358013ab603ab68121bb8471d5 542 Gene3D G3DSA:3.50.50.60 7 202 1.9E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16940 c1247e358013ab603ab68121bb8471d5 542 Pfam PF12831 FAD dependent oxidoreductase 12 514 6.1E-112 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal UA74_16940 c1247e358013ab603ab68121bb8471d5 542 SUPERFAMILY SSF51905 2 267 2.64E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 7.2E-97 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 37 480 1.6E-147 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 SUPERFAMILY SSF81442 26 535 2.35E-174 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 Gene3D G3DSA:1.20.210.10 16 541 1.1E-204 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_06150 04b9bd97b02b4660cbc3939f84f452a1 594 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 9.0E-215 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 262 273 3.2E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 122 138 3.2E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 139 154 3.2E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 181 203 3.2E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 338 349 3.2E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 75 86 3.2E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 281 308 3.2E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 309 324 3.2E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00359 B-class P450 signature 329 338 3.2E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 331 340 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00385 P450 superfamily signature 262 273 3.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00385 P450 superfamily signature 338 349 3.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00385 P450 superfamily signature 228 245 3.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 PRINTS PR00385 P450 superfamily signature 329 338 3.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 Gene3D G3DSA:1.10.630.10 7 389 3.9E-102 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 SUPERFAMILY SSF48264 5 389 2.62E-78 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_06655 22d660f489d3d57ca4baf7902b28beb3 389 Pfam PF00067 Cytochrome P450 261 358 1.3E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_19805 b1bcb022473db4b9d6955dea6dba6c7d 383 SUPERFAMILY SSF53335 3 209 1.11E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_19805 b1bcb022473db4b9d6955dea6dba6c7d 383 Gene3D G3DSA:3.40.50.150 4 246 1.5E-48 T 12-10-2018 UA74_19805 b1bcb022473db4b9d6955dea6dba6c7d 383 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 91 210 8.1E-26 T 12-10-2018 UA74_15350 2bd62263e2bcfba4844c16b1896d2c88 175 Pfam PF01738 Dienelactone hydrolase family 92 161 6.4E-7 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 UA74_15350 2bd62263e2bcfba4844c16b1896d2c88 175 SUPERFAMILY SSF53474 86 163 9.43E-6 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15350 2bd62263e2bcfba4844c16b1896d2c88 175 Gene3D G3DSA:3.40.50.1820 47 163 4.2E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17130 822530f4634172dc22c1e4e79458696d 522 Gene3D G3DSA:3.30.420.350 181 303 8.8E-13 T 12-10-2018 UA74_17130 822530f4634172dc22c1e4e79458696d 522 Pfam PF02543 Carbamoyltransferase N-terminus 101 308 6.7E-17 T 12-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 UA74_17130 822530f4634172dc22c1e4e79458696d 522 Pfam PF16861 Carbamoyltransferase C-terminus 354 517 1.2E-52 T 12-10-2018 IPR031730 Carbamoyltransferase, C-terminal UA74_17130 822530f4634172dc22c1e4e79458696d 522 Gene3D G3DSA:3.90.870.20 324 518 6.0E-54 T 12-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily UA74_12450 6418e8a6e8e4c9a29f69efc9d8052647 286 Gene3D G3DSA:3.40.30.10 140 285 1.3E-23 T 12-10-2018 UA74_12450 6418e8a6e8e4c9a29f69efc9d8052647 286 ProSitePatterns PS00194 Thioredoxin family active site. 173 191 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_12450 6418e8a6e8e4c9a29f69efc9d8052647 286 Pfam PF08534 Redoxin 147 244 2.9E-15 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 UA74_12450 6418e8a6e8e4c9a29f69efc9d8052647 286 SUPERFAMILY SSF52833 147 281 3.94E-25 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_12345 0bcc0832fe82bb07063c4405ae7b72ab 328 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 2.1E-24 T 12-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain UA74_12345 0bcc0832fe82bb07063c4405ae7b72ab 328 Gene3D G3DSA:1.10.10.10 216 307 3.7E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12345 0bcc0832fe82bb07063c4405ae7b72ab 328 Gene3D G3DSA:3.10.28.10 2 214 4.2E-20 T 12-10-2018 IPR027434 Homing endonuclease UA74_12345 0bcc0832fe82bb07063c4405ae7b72ab 328 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 1.0E-103 T 12-10-2018 IPR033981 Sporulation regulator WhiA-like UA74_12345 0bcc0832fe82bb07063c4405ae7b72ab 328 Pfam PF02650 WhiA C-terminal HTH domain 221 303 6.3E-19 T 12-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal UA74_12345 0bcc0832fe82bb07063c4405ae7b72ab 328 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 1.1E-23 T 12-10-2018 IPR039518 WhiA, LAGLIDADG-like domain UA74_12345 0bcc0832fe82bb07063c4405ae7b72ab 328 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.325 T 12-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 UA74_12875 874a46c37dcff9f22c096c594377bbdf 499 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 2 485 1.3E-230 T 12-10-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 UA74_12875 874a46c37dcff9f22c096c594377bbdf 499 PIRSF PIRSF018077 8 496 4.3E-202 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 UA74_12875 874a46c37dcff9f22c096c594377bbdf 499 Pfam PF03136 Pup-ligase protein 3 454 3.6E-180 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 UA74_13565 120337d6d8e3407597d72959d0c988aa 485 Gene3D G3DSA:3.40.309.10 263 453 2.5E-166 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_13565 120337d6d8e3407597d72959d0c988aa 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 UA74_13565 120337d6d8e3407597d72959d0c988aa 485 Gene3D G3DSA:3.40.605.10 24 481 2.5E-166 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_13565 120337d6d8e3407597d72959d0c988aa 485 SUPERFAMILY SSF53720 20 483 3.93E-153 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_13565 120337d6d8e3407597d72959d0c988aa 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UA74_13565 120337d6d8e3407597d72959d0c988aa 485 Pfam PF00171 Aldehyde dehydrogenase family 28 483 1.4E-159 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_16280 2b77c5ad3ce920f311c8be50e0a2871b 332 Gene3D G3DSA:1.10.150.130 34 138 2.1E-12 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_16280 2b77c5ad3ce920f311c8be50e0a2871b 332 Gene3D G3DSA:1.10.443.10 148 327 5.4E-17 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_16280 2b77c5ad3ce920f311c8be50e0a2871b 332 Pfam PF00589 Phage integrase family 153 311 5.2E-10 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_16280 2b77c5ad3ce920f311c8be50e0a2871b 332 SUPERFAMILY SSF56349 37 319 2.06E-36 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_07655 e5f6be0be6500e281abf6e9d27f8d108 325 Gene3D G3DSA:3.40.50.300 23 264 4.8E-60 T 12-10-2018 UA74_07655 e5f6be0be6500e281abf6e9d27f8d108 325 SUPERFAMILY SSF52540 24 238 4.02E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07655 e5f6be0be6500e281abf6e9d27f8d108 325 Pfam PF00005 ABC transporter 40 177 1.3E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_07655 e5f6be0be6500e281abf6e9d27f8d108 325 SMART SM00382 48 226 2.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 Pfam PF00750 tRNA synthetases class I (R) 118 452 1.8E-103 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 37 582 1.7E-140 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 SMART SM00836 466 582 8.9E-39 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 582 24.94 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 SUPERFAMILY SSF55190 13 102 3.01E-18 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 SMART SM01016 8 91 3.7E-22 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 127 138 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 13 91 4.8E-20 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 134 1.5E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 134 150 1.5E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 310 331 1.5E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 PRINTS PR01038 Arginyl-tRNA synthetase signature 158 171 1.5E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 Gene3D G3DSA:3.40.50.620 114 459 9.7E-99 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 SUPERFAMILY SSF52374 114 458 1.05E-84 T 12-10-2018 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 Gene3D G3DSA:1.10.730.10 460 582 1.2E-29 T 12-10-2018 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 Pfam PF05746 DALR anticodon binding domain 466 582 3.6E-28 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 Gene3D G3DSA:3.30.1360.70 7 110 3.3E-24 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UA74_00170 7e397a499fd8c00a13d6b43d54dcd19c 582 SUPERFAMILY SSF47323 460 582 2.49E-33 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_27750 c83ae10e70374287cf5fd271cd1f8788 435 SUPERFAMILY SSF52540 42 370 1.35E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_27750 c83ae10e70374287cf5fd271cd1f8788 435 Gene3D G3DSA:3.40.50.300 233 391 2.0E-5 T 12-10-2018 UA74_27750 c83ae10e70374287cf5fd271cd1f8788 435 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 42 142 4.9E-17 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_27750 c83ae10e70374287cf5fd271cd1f8788 435 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 292 366 4.0E-15 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_14900 ebc7d04e6f6ca532ea91c9bb031b2400 674 SUPERFAMILY SSF52540 180 417 4.61E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14900 ebc7d04e6f6ca532ea91c9bb031b2400 674 Pfam PF00176 SNF2 family N-terminal domain 188 482 1.5E-57 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 UA74_14900 ebc7d04e6f6ca532ea91c9bb031b2400 674 SMART SM00487 181 389 2.3E-28 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_14900 ebc7d04e6f6ca532ea91c9bb031b2400 674 Pfam PF00271 Helicase conserved C-terminal domain 503 613 3.8E-13 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_14900 ebc7d04e6f6ca532ea91c9bb031b2400 674 Gene3D G3DSA:3.40.50.10810 161 416 1.5E-64 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily UA74_14900 ebc7d04e6f6ca532ea91c9bb031b2400 674 Gene3D G3DSA:1.20.120.850 439 662 2.4E-74 T 12-10-2018 UA74_14900 ebc7d04e6f6ca532ea91c9bb031b2400 674 Gene3D G3DSA:3.40.50.300 424 627 2.4E-74 T 12-10-2018 UA74_14900 ebc7d04e6f6ca532ea91c9bb031b2400 674 SMART SM00490 527 613 5.5E-18 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_14900 ebc7d04e6f6ca532ea91c9bb031b2400 674 SUPERFAMILY SSF52540 419 670 6.38E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19835 580d402b738a74f51cfa6740696e7092 292 Gene3D G3DSA:3.40.50.10490 158 280 1.2E-18 T 12-10-2018 UA74_19835 580d402b738a74f51cfa6740696e7092 292 Gene3D G3DSA:3.40.50.10490 7 156 7.1E-22 T 12-10-2018 UA74_19835 580d402b738a74f51cfa6740696e7092 292 SUPERFAMILY SSF53697 5 289 2.52E-36 T 12-10-2018 UA74_00135 2edbf5ca4038d692b793002519a509ff 494 SMART SM00220 12 273 1.3E-55 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_00135 2edbf5ca4038d692b793002519a509ff 494 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 138 150 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_00135 2edbf5ca4038d692b793002519a509ff 494 Gene3D G3DSA:3.30.200.20 2 98 3.1E-33 T 12-10-2018 UA74_00135 2edbf5ca4038d692b793002519a509ff 494 Gene3D G3DSA:1.10.510.10 100 279 1.4E-49 T 12-10-2018 UA74_00135 2edbf5ca4038d692b793002519a509ff 494 PIRSF PIRSF000654 25 264 7.6E-22 T 12-10-2018 UA74_00135 2edbf5ca4038d692b793002519a509ff 494 SUPERFAMILY SSF56112 9 293 4.79E-73 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_00135 2edbf5ca4038d692b793002519a509ff 494 Pfam PF00069 Protein kinase domain 13 262 4.0E-43 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_07965 82d94433ceda07950ec367aee36fc188 274 Gene3D G3DSA:3.60.15.10 10 243 1.1E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_07965 82d94433ceda07950ec367aee36fc188 274 SUPERFAMILY SSF56281 13 253 1.62E-40 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_07965 82d94433ceda07950ec367aee36fc188 274 Pfam PF00753 Metallo-beta-lactamase superfamily 32 220 2.5E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_07965 82d94433ceda07950ec367aee36fc188 274 SMART SM00849 29 220 1.1E-19 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_05315 1016c60cb20d3d1298109e527d8340bb 302 Pfam PF12697 Alpha/beta hydrolase family 42 292 2.7E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05315 1016c60cb20d3d1298109e527d8340bb 302 SUPERFAMILY SSF53474 12 296 8.03E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05315 1016c60cb20d3d1298109e527d8340bb 302 Gene3D G3DSA:3.40.50.1820 6 296 4.9E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26450 a4265845921fb3f7d1fd0f9db0b7a29e 206 Gene3D G3DSA:3.40.50.1820 24 198 1.8E-18 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26450 a4265845921fb3f7d1fd0f9db0b7a29e 206 SUPERFAMILY SSF53474 4 200 2.09E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 Gene3D G3DSA:2.130.10.10 871 1066 1.2E-23 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 Gene3D G3DSA:2.130.10.10 782 870 2.7E-11 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 Pfam PF00400 WD domain, G-beta repeat 1086 1107 0.036 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 Pfam PF00400 WD domain, G-beta repeat 1299 1337 0.15 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 Pfam PF00400 WD domain, G-beta repeat 914 936 0.16 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 Pfam PF13191 AAA ATPase domain 267 414 5.5E-8 T 12-10-2018 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 Gene3D G3DSA:2.130.10.10 1250 1401 5.3E-22 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1255 1294 0.043 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1068 1107 0.0024 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 816 856 0.038 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1297 1337 0.0014 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 899 937 6.9E-4 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1340 1382 13.0 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 1151 1200 290.0 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SMART SM00320 991 1029 7.0 T 12-10-2018 IPR001680 WD40 repeat GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1324 1338 - T 12-10-2018 IPR019775 WD40 repeat, conserved site UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 Gene3D G3DSA:2.130.10.10 1067 1239 5.6E-18 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SUPERFAMILY SSF50978 824 1185 4.03E-39 T 12-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 UA74_06760 f773c918c13b83176e195d1a1c70ae9b 1416 SUPERFAMILY SSF82171 1056 1393 5.49E-33 T 12-10-2018 UA74_21440 52770327d5978af88db014fea501cd93 518 Gene3D G3DSA:3.40.309.10 258 459 9.7E-134 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_21440 52770327d5978af88db014fea501cd93 518 SUPERFAMILY SSF53720 6 493 1.31E-131 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_21440 52770327d5978af88db014fea501cd93 518 Pfam PF00171 Aldehyde dehydrogenase family 25 491 1.5E-127 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_21440 52770327d5978af88db014fea501cd93 518 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UA74_21440 52770327d5978af88db014fea501cd93 518 Gene3D G3DSA:3.40.605.10 27 485 9.7E-134 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_13150 a5e251fbdd5eddb44f6905bc2c13429a 138 SUPERFAMILY SSF54631 3 117 1.39E-26 T 12-10-2018 UA74_13150 a5e251fbdd5eddb44f6905bc2c13429a 138 Pfam PF00571 CBS domain 70 116 8.0E-8 T 12-10-2018 IPR000644 CBS domain UA74_13150 a5e251fbdd5eddb44f6905bc2c13429a 138 Pfam PF00571 CBS domain 5 57 2.0E-7 T 12-10-2018 IPR000644 CBS domain UA74_13150 a5e251fbdd5eddb44f6905bc2c13429a 138 SMART SM00116 11 59 1.6 T 12-10-2018 IPR000644 CBS domain UA74_13150 a5e251fbdd5eddb44f6905bc2c13429a 138 SMART SM00116 77 124 1.1E-4 T 12-10-2018 IPR000644 CBS domain UA74_13150 a5e251fbdd5eddb44f6905bc2c13429a 138 Gene3D G3DSA:3.10.580.10 1 123 2.0E-30 T 12-10-2018 UA74_30075 a3b3a89ab6502731dbc11d1ecb3ec46c 266 SUPERFAMILY SSF53474 16 262 1.36E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_30075 a3b3a89ab6502731dbc11d1ecb3ec46c 266 Gene3D G3DSA:3.40.50.1820 11 261 3.7E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_30075 a3b3a89ab6502731dbc11d1ecb3ec46c 266 Pfam PF00561 alpha/beta hydrolase fold 23 248 2.3E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_30075 a3b3a89ab6502731dbc11d1ecb3ec46c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.8E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_30075 a3b3a89ab6502731dbc11d1ecb3ec46c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.8E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_30075 a3b3a89ab6502731dbc11d1ecb3ec46c 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 1.8E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_08965 accdca4c0077c86d34acf74806544b66 253 SUPERFAMILY SSF53335 27 202 1.66E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_08965 accdca4c0077c86d34acf74806544b66 253 Pfam PF08241 Methyltransferase domain 58 152 1.4E-17 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_08965 accdca4c0077c86d34acf74806544b66 253 Gene3D G3DSA:3.40.50.150 13 242 2.6E-29 T 12-10-2018 UA74_19010 457a199dc9545a84520b52786ec2d06d 489 SUPERFAMILY SSF51735 2 280 1.12E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_19010 457a199dc9545a84520b52786ec2d06d 489 Pfam PF11066 Protein of unknown function (DUF2867) 328 472 2.6E-41 T 12-10-2018 IPR021295 Protein of unknown function DUF2867 UA74_19010 457a199dc9545a84520b52786ec2d06d 489 SUPERFAMILY SSF55961 337 482 9.7E-10 T 12-10-2018 UA74_19010 457a199dc9545a84520b52786ec2d06d 489 Gene3D G3DSA:3.40.50.720 2 296 1.9E-46 T 12-10-2018 UA74_19010 457a199dc9545a84520b52786ec2d06d 489 Pfam PF13460 NAD(P)H-binding 7 114 2.8E-21 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_25720 c119ccd8e4c6ade1e89268009545c200 136 Pfam PF01042 Endoribonuclease L-PSP 17 134 1.0E-21 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UA74_25720 c119ccd8e4c6ade1e89268009545c200 136 SUPERFAMILY SSF55298 2 135 2.04E-29 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_25720 c119ccd8e4c6ade1e89268009545c200 136 Gene3D G3DSA:3.30.1330.40 2 136 1.3E-31 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_07535 b6cdfd610e7c64b1419e7af0a774249b 492 Gene3D G3DSA:1.20.1720.10 32 239 1.8E-44 T 12-10-2018 UA74_07535 b6cdfd610e7c64b1419e7af0a774249b 492 Pfam PF07690 Major Facilitator Superfamily 38 427 2.0E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_07535 b6cdfd610e7c64b1419e7af0a774249b 492 ProSitePatterns PS00216 Sugar transport proteins signature 1. 86 102 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_07535 b6cdfd610e7c64b1419e7af0a774249b 492 SUPERFAMILY SSF103473 15 476 7.98E-67 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_07535 b6cdfd610e7c64b1419e7af0a774249b 492 Gene3D G3DSA:1.20.1250.20 275 482 1.4E-20 T 12-10-2018 UA74_21125 a8459373e39ca6902f44758c2b3e88af 300 SUPERFAMILY SSF103481 30 130 3.14E-12 T 12-10-2018 UA74_21125 a8459373e39ca6902f44758c2b3e88af 300 SUPERFAMILY SSF103481 175 276 1.14E-14 T 12-10-2018 UA74_21125 a8459373e39ca6902f44758c2b3e88af 300 Pfam PF00892 EamA-like transporter family 139 272 3.4E-22 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_21125 a8459373e39ca6902f44758c2b3e88af 300 Pfam PF00892 EamA-like transporter family 2 126 7.9E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_22305 547ac22be514b4119936a501a04456f5 249 Gene3D G3DSA:3.40.50.720 1 246 2.4E-72 T 12-10-2018 UA74_22305 547ac22be514b4119936a501a04456f5 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 241 3.6E-55 T 12-10-2018 UA74_22305 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 9.7E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22305 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 9.7E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22305 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 9.7E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22305 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.7E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22305 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 9.7E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22305 547ac22be514b4119936a501a04456f5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 9.7E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22305 547ac22be514b4119936a501a04456f5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 5.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22305 547ac22be514b4119936a501a04456f5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 5.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22305 547ac22be514b4119936a501a04456f5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 5.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22305 547ac22be514b4119936a501a04456f5 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_22305 547ac22be514b4119936a501a04456f5 249 SUPERFAMILY SSF51735 6 243 7.18E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_07690 de4d8edb0ef304f40021eb8e81593701 85 Gene3D G3DSA:1.10.10.1150 9 84 2.2E-6 T 12-10-2018 UA74_07690 de4d8edb0ef304f40021eb8e81593701 85 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 18 82 4.0E-11 T 12-10-2018 IPR008792 Coenzyme PQQ synthesis D UA74_22745 90af52d19b83875f5ae009b09172e24c 60 SUPERFAMILY SSF103473 14 60 7.59E-6 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_28635 e24006fb341489b2ed5f7841639e2bb7 437 Pfam PF04286 Protein of unknown function (DUF445) 73 435 4.1E-110 T 12-10-2018 IPR007383 Protein of unknown function DUF445 UA74_23555 99bb19a1f73898c52b947d62ec85bc76 352 Gene3D G3DSA:3.40.50.2300 175 304 2.9E-69 T 12-10-2018 UA74_23555 99bb19a1f73898c52b947d62ec85bc76 352 SUPERFAMILY SSF53822 70 342 1.32E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_23555 99bb19a1f73898c52b947d62ec85bc76 352 Pfam PF13377 Periplasmic binding protein-like domain 184 341 3.0E-31 T 12-10-2018 UA74_23555 99bb19a1f73898c52b947d62ec85bc76 352 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 12-10-2018 UA74_23555 99bb19a1f73898c52b947d62ec85bc76 352 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 57 2.3E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_23555 99bb19a1f73898c52b947d62ec85bc76 352 Gene3D G3DSA:3.40.50.2300 71 319 2.9E-69 T 12-10-2018 UA74_23555 99bb19a1f73898c52b947d62ec85bc76 352 SMART SM00354 9 80 8.9E-25 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_23555 99bb19a1f73898c52b947d62ec85bc76 352 SUPERFAMILY SSF47413 9 69 1.22E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_23555 99bb19a1f73898c52b947d62ec85bc76 352 Gene3D G3DSA:1.10.260.40 9 68 1.1E-18 T 12-10-2018 UA74_13830 5775101483aa8f24d39c3f7c61645573 134 SMART SM00422 1 69 4.8E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13830 5775101483aa8f24d39c3f7c61645573 134 SUPERFAMILY SSF46955 3 115 1.9E-25 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_13830 5775101483aa8f24d39c3f7c61645573 134 Pfam PF13411 MerR HTH family regulatory protein 3 63 3.9E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13830 5775101483aa8f24d39c3f7c61645573 134 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13830 5775101483aa8f24d39c3f7c61645573 134 Gene3D G3DSA:1.10.1660.10 1 126 2.6E-27 T 12-10-2018 UA74_25700 7bea361682b1f5024904cc4e3cf8cfee 632 Pfam PF13684 Dihydroxyacetone kinase family 312 632 3.4E-71 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain UA74_25700 7bea361682b1f5024904cc4e3cf8cfee 632 SMART SM01121 310 632 2.1E-71 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain UA74_25700 7bea361682b1f5024904cc4e3cf8cfee 632 Gene3D G3DSA:1.25.40.340 3 203 9.4E-12 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_25700 7bea361682b1f5024904cc4e3cf8cfee 632 Pfam PF02734 DAK2 domain 35 200 1.4E-32 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_25700 7bea361682b1f5024904cc4e3cf8cfee 632 SMART SM01120 35 201 1.5E-45 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_25700 7bea361682b1f5024904cc4e3cf8cfee 632 SUPERFAMILY SSF101473 5 202 7.32E-34 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UA74_06750 0ebea713e0c65a383a1ae8d3be88bacc 295 SUPERFAMILY SSF161098 23 295 3.74E-64 T 12-10-2018 IPR035906 MetI-like superfamily UA74_06750 0ebea713e0c65a383a1ae8d3be88bacc 295 Gene3D G3DSA:1.10.3720.10 20 285 1.7E-56 T 12-10-2018 IPR035906 MetI-like superfamily UA74_06750 0ebea713e0c65a383a1ae8d3be88bacc 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 284 1.3E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_10830 4f70659380acdef76d1badbc97275d1b 250 SUPERFAMILY SSF75625 3 246 1.44E-87 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_10830 4f70659380acdef76d1badbc97275d1b 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 238 1.4E-98 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_10830 4f70659380acdef76d1badbc97275d1b 250 Gene3D G3DSA:1.10.10.200 1 80 5.0E-31 T 12-10-2018 IPR017856 Integrase-like, N-terminal UA74_10830 4f70659380acdef76d1badbc97275d1b 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 34.4 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_10830 4f70659380acdef76d1badbc97275d1b 250 Gene3D G3DSA:3.30.70.980 135 206 9.0E-20 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_10830 4f70659380acdef76d1badbc97275d1b 250 Pfam PF01709 Transcriptional regulator 5 238 1.1E-87 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_15755 e6becd4a1eee44cd4145d24898a1e4ca 358 Gene3D G3DSA:2.160.10.10 119 240 3.8E-27 T 12-10-2018 UA74_15755 e6becd4a1eee44cd4145d24898a1e4ca 358 SUPERFAMILY SSF51161 16 83 6.28E-6 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily UA74_15755 e6becd4a1eee44cd4145d24898a1e4ca 358 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 183 211 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 UA74_15755 e6becd4a1eee44cd4145d24898a1e4ca 358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 175 208 1.2E-5 T 12-10-2018 IPR001451 Hexapeptide repeat UA74_15755 e6becd4a1eee44cd4145d24898a1e4ca 358 Gene3D G3DSA:2.160.10.10 6 118 2.6E-9 T 12-10-2018 UA74_15755 e6becd4a1eee44cd4145d24898a1e4ca 358 SUPERFAMILY SSF51161 68 228 6.97E-31 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily UA74_30180 0b939c15616cf615ee370f4d3785663b 756 SUPERFAMILY SSF82866 449 689 1.44E-28 T 12-10-2018 UA74_30180 0b939c15616cf615ee370f4d3785663b 756 SUPERFAMILY SSF82866 136 334 1.23E-30 T 12-10-2018 UA74_30180 0b939c15616cf615ee370f4d3785663b 756 Pfam PF03176 MMPL family 396 692 2.3E-29 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UA74_30180 0b939c15616cf615ee370f4d3785663b 756 Pfam PF03176 MMPL family 47 366 6.2E-45 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UA74_30180 0b939c15616cf615ee370f4d3785663b 756 Gene3D G3DSA:1.20.1640.10 155 337 8.4E-11 T 12-10-2018 UA74_00655 38aa5bd9077b3473bdad21dd0ac0ec17 228 SUPERFAMILY SSF53448 6 210 1.34E-28 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_00655 38aa5bd9077b3473bdad21dd0ac0ec17 228 Gene3D G3DSA:3.90.550.10 3 228 5.0E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_00655 38aa5bd9077b3473bdad21dd0ac0ec17 228 Pfam PF00535 Glycosyl transferase family 2 9 130 1.7E-20 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 Gene3D G3DSA:3.40.50.720 235 461 3.7E-70 T 12-10-2018 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 SUPERFAMILY SSF53223 86 235 2.52E-55 T 12-10-2018 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 PRINTS PR00072 Malic enzyme signature 154 176 2.0E-6 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 PRINTS PR00072 Malic enzyme signature 233 249 2.0E-6 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 PRINTS PR00072 Malic enzyme signature 264 280 2.0E-6 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 Gene3D G3DSA:3.40.50.10380 78 234 7.6E-71 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 SMART SM00919 237 459 1.6E-102 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 SMART SM01274 92 225 2.5E-82 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 PIRSF PIRSF000106 23 461 2.1E-77 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 Pfam PF03949 Malic enzyme, NAD binding domain 239 458 2.1E-22 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 Pfam PF00390 Malic enzyme, N-terminal domain 94 225 3.9E-27 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UA74_28440 7031ed661269f889b1b3653f7d11c5a9 461 SUPERFAMILY SSF51735 237 460 5.71E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_26420 a761ebe8e54bd08fc6a38127be4d6fbd 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.365 T 12-10-2018 IPR003482 Transcription factor WhiB UA74_26420 a761ebe8e54bd08fc6a38127be4d6fbd 84 Pfam PF02467 Transcription factor WhiB 3 71 1.4E-26 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain UA74_25840 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 Pfam PF00694 Aconitase C-terminal domain 1 115 4.5E-23 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 UA74_25840 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 1.5E-54 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 UA74_25840 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 38.32 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 UA74_25840 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 SUPERFAMILY SSF52016 1 187 5.69E-53 T 12-10-2018 UA74_25840 6f1fd75c22e20fbd4ae4ffee8a3ad05c 200 Gene3D G3DSA:3.20.19.10 1 168 5.0E-66 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 UA74_13780 cf1f5ba3e10eb15092590e4182c8883b 584 Pfam PF09709 CRISPR-associated protein (Cas_Csd1) 16 570 4.3E-82 T 12-10-2018 IPR010144 CRISPR-associated protein, Csd1-type UA74_13780 cf1f5ba3e10eb15092590e4182c8883b 584 TIGRFAM TIGR01863 cas_Csd1: CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG 3 572 7.7E-71 T 12-10-2018 IPR010144 CRISPR-associated protein, Csd1-type UA74_09965 6a4c1d25f696e8c6721a22c822ba609d 257 Pfam PF00977 Histidine biosynthesis protein 6 240 4.2E-84 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 UA74_09965 6a4c1d25f696e8c6721a22c822ba609d 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 4 257 1.6E-107 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UA74_09965 6a4c1d25f696e8c6721a22c822ba609d 257 Gene3D G3DSA:3.20.20.70 1 257 1.6E-101 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_09965 6a4c1d25f696e8c6721a22c822ba609d 257 SUPERFAMILY SSF51366 5 257 1.02E-77 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UA74_09965 6a4c1d25f696e8c6721a22c822ba609d 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 257 46.995 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 Pfam PF07516 SecA Wing and Scaffold domain 661 745 8.9E-13 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 Gene3D G3DSA:3.40.50.300 73 424 5.6E-116 T 12-10-2018 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 SUPERFAMILY SSF81886 608 753 5.1E-26 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 SUPERFAMILY SSF52540 426 587 4.85E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 SUPERFAMILY SSF81767 265 375 3.92E-29 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 Pfam PF07517 SecA DEAD-like domain 14 410 7.4E-81 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 PRINTS PR00906 SecA protein signature 197 217 2.0E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 PRINTS PR00906 SecA protein signature 385 402 2.0E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 PRINTS PR00906 SecA protein signature 422 435 2.0E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 PRINTS PR00906 SecA protein signature 90 114 2.0E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 PRINTS PR00906 SecA protein signature 144 154 2.0E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 PRINTS PR00906 SecA protein signature 348 370 2.0E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 PRINTS PR00906 SecA protein signature 128 142 2.0E-39 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 SMART SM00957 12 411 8.1E-131 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 Pfam PF01043 SecA preprotein cross-linking domain 264 367 9.6E-22 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 ProSitePatterns PS01312 SecA family signature. 509 524 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 Hamap MF_01382 Protein translocase subunit SecA [secA]. 11 752 15.161 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 SMART SM00958 259 367 3.1E-26 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 Gene3D G3DSA:1.10.3060.10 607 755 6.0E-23 T 12-10-2018 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 Gene3D G3DSA:3.40.50.300 426 530 2.1E-36 T 12-10-2018 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 Gene3D G3DSA:3.40.50.300 531 600 2.2E-20 T 12-10-2018 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 Gene3D G3DSA:3.90.1440.10 256 377 5.6E-116 T 12-10-2018 UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 9 793 0.0 T 12-10-2018 IPR026389 Protein translocase subunit SecA, Actinobacteria-type UA74_19005 7b4ac4465e534e1579496a7440c14b6b 810 SUPERFAMILY SSF52540 76 578 1.0E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20695 88a692cc3c37c32be4778d6252a34e48 342 SUPERFAMILY SSF53474 122 328 5.59E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20695 88a692cc3c37c32be4778d6252a34e48 342 Pfam PF01738 Dienelactone hydrolase family 142 262 6.8E-5 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 UA74_20695 88a692cc3c37c32be4778d6252a34e48 342 Gene3D G3DSA:3.40.50.1820 78 342 3.8E-85 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_09510 2bb6990884ad80ed1083ab513716f25a 795 SUPERFAMILY SSF46785 714 779 2.04E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_09510 2bb6990884ad80ed1083ab513716f25a 795 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 52 178 4.0E-9 T 12-10-2018 IPR025199 DNA translocase FtsK, 4TM region UA74_09510 2bb6990884ad80ed1083ab513716f25a 795 Pfam PF09397 Ftsk gamma domain 718 774 7.1E-21 T 12-10-2018 IPR018541 FtsK gamma domain UA74_09510 2bb6990884ad80ed1083ab513716f25a 795 SMART SM00843 713 777 1.2E-27 T 12-10-2018 IPR018541 FtsK gamma domain UA74_09510 2bb6990884ad80ed1083ab513716f25a 795 SUPERFAMILY SSF52540 386 684 8.86E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_09510 2bb6990884ad80ed1083ab513716f25a 795 Gene3D G3DSA:3.40.50.300 409 698 1.6E-102 T 12-10-2018 UA74_09510 2bb6990884ad80ed1083ab513716f25a 795 Gene3D G3DSA:1.10.10.10 717 778 6.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_09510 2bb6990884ad80ed1083ab513716f25a 795 Gene3D G3DSA:3.30.980.40 306 408 4.5E-30 T 12-10-2018 UA74_09510 2bb6990884ad80ed1083ab513716f25a 795 Pfam PF01580 FtsK/SpoIIIE family 412 612 2.2E-59 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_19045 44dff2fb6785aad899fa51ccd24aeea2 253 Pfam PF01061 ABC-2 type transporter 9 217 2.9E-21 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_19045 44dff2fb6785aad899fa51ccd24aeea2 253 PIRSF PIRSF006648 1 253 8.5E-67 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_22760 84be2bc69a0b5f5c1ceabcf12777e309 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_22760 84be2bc69a0b5f5c1ceabcf12777e309 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_22760 84be2bc69a0b5f5c1ceabcf12777e309 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_22760 84be2bc69a0b5f5c1ceabcf12777e309 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.7E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_22760 84be2bc69a0b5f5c1ceabcf12777e309 323 Gene3D G3DSA:1.10.10.10 3 89 7.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22760 84be2bc69a0b5f5c1ceabcf12777e309 323 SUPERFAMILY SSF53850 114 288 1.72E-16 T 12-10-2018 UA74_22760 84be2bc69a0b5f5c1ceabcf12777e309 323 Gene3D G3DSA:3.40.190.290 109 292 1.9E-16 T 12-10-2018 UA74_22760 84be2bc69a0b5f5c1ceabcf12777e309 323 Pfam PF03466 LysR substrate binding domain 116 287 3.8E-16 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_22760 84be2bc69a0b5f5c1ceabcf12777e309 323 SUPERFAMILY SSF46785 4 99 4.09E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14925 29c4144103b45e6bb361db44d8d72351 311 SUPERFAMILY SSF51735 31 185 6.81E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14925 29c4144103b45e6bb361db44d8d72351 311 Gene3D G3DSA:3.40.50.720 26 185 1.5E-35 T 12-10-2018 UA74_14925 29c4144103b45e6bb361db44d8d72351 311 Gene3D G3DSA:1.10.1040.10 187 309 4.5E-28 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_14925 29c4144103b45e6bb361db44d8d72351 311 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 31 182 2.0E-18 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UA74_14925 29c4144103b45e6bb361db44d8d72351 311 PIRSF PIRSF000103 23 308 5.0E-32 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 PIRSF PIRSF006641 42 401 9.7E-139 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 Gene3D G3DSA:1.10.150.300 155 240 1.1E-137 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 44 401 42.754 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 129 147 6.2E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 47 67 6.2E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 68 86 6.2E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 112 127 6.2E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 Gene3D G3DSA:3.40.50.300 46 316 1.1E-137 T 12-10-2018 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 SUPERFAMILY SSF81271 317 401 3.27E-34 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 Pfam PF06071 Protein of unknown function (DUF933) 317 400 9.1E-38 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 SUPERFAMILY SSF52540 45 339 4.56E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 Gene3D G3DSA:3.10.20.30 90 399 1.1E-137 T 12-10-2018 IPR012675 Beta-grasp domain superfamily UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 Pfam PF01926 50S ribosome-binding GTPase 47 169 2.7E-21 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 UA74_04210 2f865674f0d7f489391d958a7f85cc76 401 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 45 401 7.1E-132 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 UA74_20400 bcebe95f40d0639b22ef65d212b07f6e 269 SUPERFAMILY SSF53098 15 207 2.94E-39 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_20400 bcebe95f40d0639b22ef65d212b07f6e 269 SMART SM00479 19 194 2.4E-14 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_20400 bcebe95f40d0639b22ef65d212b07f6e 269 Gene3D G3DSA:3.30.420.10 15 201 5.8E-34 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_20400 bcebe95f40d0639b22ef65d212b07f6e 269 Pfam PF00929 Exonuclease 22 184 3.9E-10 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_25335 4ab9c72c14e2cf7cedbc50cac0ff5bd2 154 PIRSF PIRSF000239 1 151 1.4E-23 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_25335 4ab9c72c14e2cf7cedbc50cac0ff5bd2 154 Gene3D G3DSA:3.40.30.10 1 153 7.3E-50 T 12-10-2018 UA74_25335 4ab9c72c14e2cf7cedbc50cac0ff5bd2 154 Pfam PF00578 AhpC/TSA family 5 130 1.9E-36 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_25335 4ab9c72c14e2cf7cedbc50cac0ff5bd2 154 SUPERFAMILY SSF52833 1 152 5.79E-46 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_06460 a1f58ca51e2b005e65cbe6f7dfafde49 472 Pfam PF13193 AMP-binding enzyme C-terminal domain 388 455 3.6E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_06460 a1f58ca51e2b005e65cbe6f7dfafde49 472 Gene3D G3DSA:3.30.300.30 376 468 1.8E-14 T 12-10-2018 UA74_06460 a1f58ca51e2b005e65cbe6f7dfafde49 472 Pfam PF00501 AMP-binding enzyme 28 323 2.5E-30 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_06460 a1f58ca51e2b005e65cbe6f7dfafde49 472 SUPERFAMILY SSF56801 11 458 2.35E-74 T 12-10-2018 UA74_06460 a1f58ca51e2b005e65cbe6f7dfafde49 472 Gene3D G3DSA:3.40.50.12780 13 375 3.5E-45 T 12-10-2018 UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 SUPERFAMILY SSF52402 292 557 4.44E-72 T 12-10-2018 UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 4 575 29.059 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 SUPERFAMILY SSF56317 1 256 2.22E-60 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 Pfam PF02540 NAD synthase 302 549 7.7E-69 T 12-10-2018 IPR022310 NAD/GMP synthase UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 PIRSF PIRSF006630 1 577 3.0E-202 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 Gene3D G3DSA:3.60.110.10 1 283 3.2E-98 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 36 51 - T 12-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 Pfam PF00795 Carbon-nitrogen hydrolase 6 250 8.8E-28 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 Gene3D G3DSA:3.40.50.620 299 577 9.4E-108 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_25165 d90e7b44afa8968aea1e8dbaf53ba4c6 585 TIGRFAM TIGR00552 nadE: NAD+ synthetase 305 552 1.2E-55 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 UA74_01595 d5bb3ca80761a8b3f41ed9248ef56c3b 321 SUPERFAMILY SSF52374 16 293 3.49E-100 T 12-10-2018 UA74_01595 d5bb3ca80761a8b3f41ed9248ef56c3b 321 Gene3D G3DSA:3.40.50.620 6 190 1.5E-75 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_01595 d5bb3ca80761a8b3f41ed9248ef56c3b 321 Gene3D G3DSA:3.30.1300.10 191 304 4.1E-34 T 12-10-2018 UA74_01595 d5bb3ca80761a8b3f41ed9248ef56c3b 321 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 23 290 1.8E-81 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 UA74_01595 d5bb3ca80761a8b3f41ed9248ef56c3b 321 Pfam PF02569 Pantoate-beta-alanine ligase 20 288 1.6E-92 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 UA74_01595 d5bb3ca80761a8b3f41ed9248ef56c3b 321 Hamap MF_00158 Pantothenate synthetase [panC]. 17 290 37.453 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 PRINTS PR00773 GrpE protein signature 130 146 1.0E-22 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 PRINTS PR00773 GrpE protein signature 205 220 1.0E-22 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 PRINTS PR00773 GrpE protein signature 232 251 1.0E-22 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 PRINTS PR00773 GrpE protein signature 158 173 1.0E-22 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 Hamap MF_01151 Protein GrpE [grpE]. 5 253 16.373 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 SUPERFAMILY SSF51064 199 253 7.06E-15 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 Gene3D G3DSA:3.90.20.20 87 195 1.6E-14 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 ProSitePatterns PS01071 grpE protein signature. 208 251 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 Gene3D G3DSA:2.30.22.10 197 252 1.6E-16 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 SUPERFAMILY SSF58014 109 197 9.94E-16 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 UA74_29705 5fe00caf5579465d0137fa682572eb8f 291 Pfam PF01025 GrpE 111 252 6.1E-31 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_23590 7e87794a802c1a712e396fa79dd9b064 393 Gene3D G3DSA:3.20.20.80 253 393 1.3E-18 T 12-10-2018 UA74_23590 7e87794a802c1a712e396fa79dd9b064 393 Gene3D G3DSA:3.20.20.80 12 252 6.1E-47 T 12-10-2018 UA74_23590 7e87794a802c1a712e396fa79dd9b064 393 Pfam PF00232 Glycosyl hydrolase family 1 322 389 6.1E-7 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_23590 7e87794a802c1a712e396fa79dd9b064 393 Pfam PF00232 Glycosyl hydrolase family 1 23 252 7.8E-31 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_23590 7e87794a802c1a712e396fa79dd9b064 393 SUPERFAMILY SSF51445 22 392 7.55E-68 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_04335 0795bcd14f491ae1d77420c5f10a43a4 334 Gene3D G3DSA:3.40.50.300 22 260 2.9E-57 T 12-10-2018 UA74_04335 0795bcd14f491ae1d77420c5f10a43a4 334 Pfam PF00005 ABC transporter 46 190 1.6E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_04335 0795bcd14f491ae1d77420c5f10a43a4 334 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_04335 0795bcd14f491ae1d77420c5f10a43a4 334 SUPERFAMILY SSF52540 29 252 6.64E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04335 0795bcd14f491ae1d77420c5f10a43a4 334 SMART SM00382 54 237 1.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28410 5765fc1448636651f24448a80d6acac3 89 Gene3D G3DSA:3.10.20.30 8 89 2.2E-16 T 12-10-2018 IPR012675 Beta-grasp domain superfamily UA74_28410 5765fc1448636651f24448a80d6acac3 89 SUPERFAMILY SSF54285 8 87 4.71E-10 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp UA74_28410 5765fc1448636651f24448a80d6acac3 89 Pfam PF02597 ThiS family 11 89 4.7E-8 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 UA74_21985 b5307145eae587f63482cc6126d4ff84 224 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 43 202 7.9E-30 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_21985 b5307145eae587f63482cc6126d4ff84 224 Pfam PF04542 Sigma-70 region 2 47 114 6.4E-21 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_21985 b5307145eae587f63482cc6126d4ff84 224 SUPERFAMILY SSF88946 26 125 9.26E-28 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_21985 b5307145eae587f63482cc6126d4ff84 224 Gene3D G3DSA:1.10.10.10 111 206 6.4E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21985 b5307145eae587f63482cc6126d4ff84 224 Gene3D G3DSA:1.10.1740.10 29 110 3.9E-29 T 12-10-2018 UA74_21985 b5307145eae587f63482cc6126d4ff84 224 SUPERFAMILY SSF88659 146 205 7.85E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_21985 b5307145eae587f63482cc6126d4ff84 224 Pfam PF04545 Sigma-70, region 4 153 201 1.2E-14 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UA74_03565 a9d5b9a2dbaf3b1b59d03aed700de98e 1105 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 434 444 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_03565 a9d5b9a2dbaf3b1b59d03aed700de98e 1105 Pfam PF00082 Subtilase family 223 483 1.3E-53 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_03565 a9d5b9a2dbaf3b1b59d03aed700de98e 1105 Gene3D G3DSA:3.40.50.200 199 495 5.8E-92 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_03565 a9d5b9a2dbaf3b1b59d03aed700de98e 1105 SUPERFAMILY SSF52743 207 492 8.51E-79 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_03565 a9d5b9a2dbaf3b1b59d03aed700de98e 1105 PRINTS PR00723 Subtilisin serine protease family (S8) signature 433 449 1.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_03565 a9d5b9a2dbaf3b1b59d03aed700de98e 1105 PRINTS PR00723 Subtilisin serine protease family (S8) signature 223 242 1.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_03565 a9d5b9a2dbaf3b1b59d03aed700de98e 1105 PRINTS PR00723 Subtilisin serine protease family (S8) signature 261 274 1.9E-20 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_14425 70e508c11deb1d743d155fe21d3eb164 362 Pfam PF01032 FecCD transport family 51 355 3.2E-65 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_14425 70e508c11deb1d743d155fe21d3eb164 362 Gene3D G3DSA:1.10.3470.10 36 360 3.8E-69 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_14425 70e508c11deb1d743d155fe21d3eb164 362 SUPERFAMILY SSF81345 33 355 1.83E-55 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_17560 4bcbc44d122c2edee258e51b0f5d3b6c 370 SUPERFAMILY SSF51445 17 304 5.13E-6 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_17560 4bcbc44d122c2edee258e51b0f5d3b6c 370 Gene3D G3DSA:3.20.20.80 52 362 1.9E-10 T 12-10-2018 UA74_27455 ba72f56c8e665535f75ab0b65e04bd32 362 Gene3D G3DSA:3.20.20.140 1 350 6.8E-100 T 12-10-2018 UA74_27455 ba72f56c8e665535f75ab0b65e04bd32 362 SUPERFAMILY SSF51556 6 352 6.43E-70 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_27455 ba72f56c8e665535f75ab0b65e04bd32 362 Hamap MF_00540 Adenosine deaminase [add]. 8 353 52.324 T 12-10-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 UA74_27455 ba72f56c8e665535f75ab0b65e04bd32 362 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 14 351 1.7E-74 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 UA74_27455 ba72f56c8e665535f75ab0b65e04bd32 362 Pfam PF00962 Adenosine/AMP deaminase 13 350 1.9E-87 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 UA74_17020 2a056bbe088db931f4b9606668e3a565 560 Pfam PF05960 Bacterial protein of unknown function (DUF885) 30 543 9.5E-130 T 12-10-2018 IPR010281 Protein of unknown function DUF885 UA74_04245 773d6770a46919a9f4ebc9a7a16c3b44 480 Pfam PF13560 Helix-turn-helix domain 12 70 4.2E-15 T 12-10-2018 UA74_04245 773d6770a46919a9f4ebc9a7a16c3b44 480 Gene3D G3DSA:1.10.260.40 10 91 1.6E-19 T 12-10-2018 UA74_04245 773d6770a46919a9f4ebc9a7a16c3b44 480 SMART SM00530 15 70 2.6E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_04245 773d6770a46919a9f4ebc9a7a16c3b44 480 Pfam PF06114 IrrE N-terminal-like domain 210 304 1.5E-9 T 12-10-2018 IPR010359 IrrE N-terminal-like domain UA74_04245 773d6770a46919a9f4ebc9a7a16c3b44 480 SUPERFAMILY SSF47413 9 75 8.16E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_00965 c5f86be3fdb5db95496e36f2a554180c 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_00965 c5f86be3fdb5db95496e36f2a554180c 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 281 1.3E-44 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_00965 c5f86be3fdb5db95496e36f2a554180c 313 Gene3D G3DSA:3.40.50.720 103 279 5.3E-89 T 12-10-2018 UA74_00965 c5f86be3fdb5db95496e36f2a554180c 313 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UA74_00965 c5f86be3fdb5db95496e36f2a554180c 313 SUPERFAMILY SSF52283 12 137 3.78E-32 T 12-10-2018 UA74_00965 c5f86be3fdb5db95496e36f2a554180c 313 Gene3D G3DSA:3.40.50.720 38 305 5.3E-89 T 12-10-2018 UA74_00965 c5f86be3fdb5db95496e36f2a554180c 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 33 310 8.1E-28 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UA74_00965 c5f86be3fdb5db95496e36f2a554180c 313 SUPERFAMILY SSF51735 103 282 2.12E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_08170 ecb8a3eed1502d514b86bc492ec09c2c 479 Pfam PF00082 Subtilase family 162 444 9.2E-40 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_08170 ecb8a3eed1502d514b86bc492ec09c2c 479 Gene3D G3DSA:3.40.50.200 129 479 1.5E-74 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_08170 ecb8a3eed1502d514b86bc492ec09c2c 479 SUPERFAMILY SSF52743 142 478 4.71E-66 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_08170 ecb8a3eed1502d514b86bc492ec09c2c 479 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 210 220 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UA74_08170 ecb8a3eed1502d514b86bc492ec09c2c 479 PRINTS PR00723 Subtilisin serine protease family (S8) signature 399 415 3.0E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_08170 ecb8a3eed1502d514b86bc492ec09c2c 479 PRINTS PR00723 Subtilisin serine protease family (S8) signature 206 219 3.0E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_08170 ecb8a3eed1502d514b86bc492ec09c2c 479 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 179 3.0E-17 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_08170 ecb8a3eed1502d514b86bc492ec09c2c 479 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 165 176 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_08170 ecb8a3eed1502d514b86bc492ec09c2c 479 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 400 410 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 Gene3D G3DSA:3.40.50.10490 10 214 3.9E-91 T 12-10-2018 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 Pfam PF00318 Ribosomal protein S2 9 224 1.6E-96 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 224 2.7E-109 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 196 210 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 87 104 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 37 46 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 6 24 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 175 186 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 PRINTS PR00395 Ribosomal protein S2 signature 158 175 6.6E-39 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 Gene3D G3DSA:1.10.287.610 97 152 3.9E-91 T 12-10-2018 UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 SUPERFAMILY SSF52313 6 228 1.83E-93 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily UA74_08940 5b66d5cb2890c3a56e2b02f9bd2ed1d4 286 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 231 42.523 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_27495 baa5d294e91f33be24ca426826776f28 145 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 23 126 1.3E-22 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27495 baa5d294e91f33be24ca426826776f28 145 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 24 127 4.3E-27 T 12-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27495 baa5d294e91f33be24ca426826776f28 145 SUPERFAMILY SSF81343 23 132 1.96E-26 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27495 baa5d294e91f33be24ca426826776f28 145 Gene3D G3DSA:1.20.1300.10 25 135 2.6E-17 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_16240 cc901b32c21d0dfb439e09b3ac2f29db 628 Gene3D G3DSA:3.40.50.300 238 575 8.9E-77 T 12-10-2018 UA74_16240 cc901b32c21d0dfb439e09b3ac2f29db 628 Gene3D G3DSA:1.10.8.730 329 433 8.9E-77 T 12-10-2018 UA74_16240 cc901b32c21d0dfb439e09b3ac2f29db 628 SUPERFAMILY SSF52540 209 572 1.22E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16240 cc901b32c21d0dfb439e09b3ac2f29db 628 Pfam PF01935 Domain of unknown function DUF87 252 315 8.0E-8 T 12-10-2018 IPR002789 Helicase HerA, central domain UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 SMART SM00363 91 156 4.8E-16 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 Pfam PF01479 S4 domain 92 138 1.2E-19 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 Gene3D G3DSA:3.10.290.10 90 186 3.9E-73 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 34.752 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 Gene3D G3DSA:1.10.1050.10 6 201 3.9E-73 T 12-10-2018 UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 3.9E-30 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 SUPERFAMILY SSF55174 3 201 3.66E-65 T 12-10-2018 UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 SMART SM01390 3 90 1.4E-44 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 UA74_03135 14c0b2c55d4d1a6716bd105531b25784 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 7.0E-79 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 UA74_22135 a2450a9c8585610c83f3b841331a8ded 384 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 83 4.6E-15 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_22135 a2450a9c8585610c83f3b841331a8ded 384 SUPERFAMILY SSF161098 169 361 1.7E-22 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22135 a2450a9c8585610c83f3b841331a8ded 384 Gene3D G3DSA:1.10.3720.10 162 376 1.7E-18 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22135 a2450a9c8585610c83f3b841331a8ded 384 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 191 377 5.8E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_23745 89e0dfb0ae25a8cde49ad02a9f6e3054 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 16 397 1.3E-125 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_23745 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Pfam PF02803 Thiolase, C-terminal domain 278 397 1.1E-36 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UA74_23745 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Gene3D G3DSA:3.40.47.10 13 279 1.1E-120 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_23745 89e0dfb0ae25a8cde49ad02a9f6e3054 406 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 UA74_23745 89e0dfb0ae25a8cde49ad02a9f6e3054 406 SUPERFAMILY SSF53901 277 397 4.45E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_23745 89e0dfb0ae25a8cde49ad02a9f6e3054 406 SUPERFAMILY SSF53901 12 273 1.68E-57 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_23745 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Gene3D G3DSA:3.40.47.10 142 391 1.1E-120 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_23745 89e0dfb0ae25a8cde49ad02a9f6e3054 406 Pfam PF00108 Thiolase, N-terminal domain 13 266 2.3E-55 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UA74_23745 89e0dfb0ae25a8cde49ad02a9f6e3054 406 PIRSF PIRSF000429 8 400 1.0E-120 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 Gene3D G3DSA:3.40.50.1980 40 199 2.4E-39 T 12-10-2018 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 SUPERFAMILY SSF53807 40 314 7.36E-68 T 12-10-2018 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 253 271 2.6E-21 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 40 58 2.6E-21 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 71 84 2.6E-21 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 198 219 2.6E-21 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 280 299 2.6E-21 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00690 Adhesin family signature 84 101 2.6E-21 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 Gene3D G3DSA:3.40.50.1980 200 317 5.8E-31 T 12-10-2018 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 40 61 5.0E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 293 311 5.0E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 84 103 5.0E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 198 215 5.0E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 PRINTS PR00691 Adhesin B signature 249 266 5.0E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 UA74_19590 b066b60f29620a1618d74606f233c7d3 318 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 312 4.9E-69 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 Pfam PF00701 Dihydrodipicolinate synthetase family 15 309 1.4E-48 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PIRSF PIRSF001365 14 317 5.0E-69 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 SUPERFAMILY SSF51569 14 313 8.27E-73 T 12-10-2018 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 82 100 7.5E-10 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 46 67 7.5E-10 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 114 130 7.5E-10 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 7.5E-10 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 Gene3D G3DSA:3.20.20.70 14 313 3.8E-87 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 144 174 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 UA74_10095 74c0eb6985e0e7ec4dd81ffa89b57bc8 318 SMART SM01130 12 312 2.8E-78 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_08995 bea8cf4a80e6beb4940a677791ff18c7 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 275 5.0E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_08995 bea8cf4a80e6beb4940a677791ff18c7 287 SUPERFAMILY SSF161098 20 278 7.85E-50 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08995 bea8cf4a80e6beb4940a677791ff18c7 287 Gene3D G3DSA:1.10.3720.10 15 284 4.3E-48 T 12-10-2018 IPR035906 MetI-like superfamily UA74_11605 edf3f07001d034fed2982bd8b18539bc 330 SUPERFAMILY SSF53474 35 302 2.9E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_11605 edf3f07001d034fed2982bd8b18539bc 330 Pfam PF12697 Alpha/beta hydrolase family 66 301 5.6E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_11605 edf3f07001d034fed2982bd8b18539bc 330 Gene3D G3DSA:3.40.50.1820 45 313 3.4E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18430 2201a81161c13562e6145d00e223b50e 307 Gene3D G3DSA:3.40.50.720 8 292 1.7E-66 T 12-10-2018 UA74_18430 2201a81161c13562e6145d00e223b50e 307 SUPERFAMILY SSF51735 8 268 1.71E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18430 2201a81161c13562e6145d00e223b50e 307 Pfam PF05368 NmrA-like family 8 245 2.7E-43 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 UA74_18430 2201a81161c13562e6145d00e223b50e 307 Gene3D G3DSA:3.90.25.10 166 298 1.7E-66 T 12-10-2018 UA74_02330 ad196d26853b740893bf5bc6c8028438 509 SUPERFAMILY SSF69618 238 489 7.46E-70 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02330 ad196d26853b740893bf5bc6c8028438 509 Gene3D G3DSA:3.40.1010.10 1 117 7.3E-25 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 UA74_02330 ad196d26853b740893bf5bc6c8028438 509 Gene3D G3DSA:3.30.950.10 118 234 4.5E-22 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 UA74_02330 ad196d26853b740893bf5bc6c8028438 509 SUPERFAMILY SSF53790 6 241 1.27E-48 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 UA74_02330 ad196d26853b740893bf5bc6c8028438 509 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UA74_02330 ad196d26853b740893bf5bc6c8028438 509 Pfam PF02602 Uroporphyrinogen-III synthase HemD 252 482 3.1E-66 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_02330 ad196d26853b740893bf5bc6c8028438 509 Gene3D G3DSA:3.40.50.10090 270 410 3.9E-50 T 12-10-2018 UA74_02330 ad196d26853b740893bf5bc6c8028438 509 Gene3D G3DSA:3.40.50.10090 241 477 3.9E-50 T 12-10-2018 UA74_02330 ad196d26853b740893bf5bc6c8028438 509 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 203 1.0E-37 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 UA74_16985 fdf66e0fdc451db69f938ec5daecaad4 333 Pfam PF05544 Proline racemase 10 331 2.0E-121 T 12-10-2018 IPR008794 Proline racemase family UA74_16985 fdf66e0fdc451db69f938ec5daecaad4 333 PIRSF PIRSF029792 1 333 1.1E-121 T 12-10-2018 IPR008794 Proline racemase family UA74_16985 fdf66e0fdc451db69f938ec5daecaad4 333 Gene3D G3DSA:3.10.310.10 7 331 6.3E-120 T 12-10-2018 UA74_16985 fdf66e0fdc451db69f938ec5daecaad4 333 Gene3D G3DSA:3.10.310.10 146 310 6.3E-120 T 12-10-2018 UA74_16985 fdf66e0fdc451db69f938ec5daecaad4 333 SUPERFAMILY SSF54506 2 331 6.73E-110 T 12-10-2018 UA74_06510 f54e0a2078b5cbed409d5e2442df0adf 550 Gene3D G3DSA:3.40.50.410 347 537 1.0E-31 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_06510 f54e0a2078b5cbed409d5e2442df0adf 550 SMART SM00327 343 537 8.7E-13 T 12-10-2018 IPR002035 von Willebrand factor, type A UA74_06510 f54e0a2078b5cbed409d5e2442df0adf 550 SUPERFAMILY SSF53300 348 533 1.63E-23 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_06510 f54e0a2078b5cbed409d5e2442df0adf 550 Pfam PF13531 Bacterial extracellular solute-binding protein 50 299 1.8E-22 T 12-10-2018 UA74_06510 f54e0a2078b5cbed409d5e2442df0adf 550 Pfam PF00092 von Willebrand factor type A domain 348 533 3.5E-10 T 12-10-2018 IPR002035 von Willebrand factor, type A UA74_23160 924acc3ccf3cb93a1a156abe1e0e8a7c 243 Gene3D G3DSA:1.10.3630.10 4 190 7.8E-11 T 12-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily UA74_23160 924acc3ccf3cb93a1a156abe1e0e8a7c 243 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 7 202 6.3E-29 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 UA74_08850 4fb2b1733dd05306d43e167cde6c8cdd 315 ProSitePatterns PS00761 Signal peptidases I signature 3. 223 236 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 UA74_08850 4fb2b1733dd05306d43e167cde6c8cdd 315 SUPERFAMILY SSF51306 78 270 7.85E-43 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily UA74_08850 4fb2b1733dd05306d43e167cde6c8cdd 315 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 66 263 1.9E-36 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UA74_08850 4fb2b1733dd05306d43e167cde6c8cdd 315 Pfam PF00717 Peptidase S24-like 86 132 3.6E-6 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C UA74_08850 4fb2b1733dd05306d43e167cde6c8cdd 315 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 95 2.2E-18 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UA74_08850 4fb2b1733dd05306d43e167cde6c8cdd 315 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 167 179 2.2E-18 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UA74_08850 4fb2b1733dd05306d43e167cde6c8cdd 315 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 218 237 2.2E-18 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UA74_08850 4fb2b1733dd05306d43e167cde6c8cdd 315 Pfam PF10502 Signal peptidase, peptidase S26 144 261 1.9E-7 T 12-10-2018 IPR019533 Peptidase S26 UA74_08850 4fb2b1733dd05306d43e167cde6c8cdd 315 Gene3D G3DSA:2.10.109.10 211 277 3.0E-12 T 12-10-2018 UA74_16675 194a3680b296fcd353db2e6128821e55 94 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site UA74_16675 194a3680b296fcd353db2e6128821e55 94 Gene3D G3DSA:3.30.1340.10 1 86 1.3E-17 T 12-10-2018 IPR035895 HPr-like superfamily UA74_16675 194a3680b296fcd353db2e6128821e55 94 SUPERFAMILY SSF55594 1 87 8.77E-16 T 12-10-2018 IPR035895 HPr-like superfamily UA74_16675 194a3680b296fcd353db2e6128821e55 94 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 1.8E-18 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_16675 194a3680b296fcd353db2e6128821e55 94 Pfam PF00381 PTS HPr component phosphorylation site 4 83 2.3E-18 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_16675 194a3680b296fcd353db2e6128821e55 94 PRINTS PR00107 Phosphocarrier protein signature 58 75 2.1E-10 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_16675 194a3680b296fcd353db2e6128821e55 94 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.1E-10 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_16675 194a3680b296fcd353db2e6128821e55 94 PRINTS PR00107 Phosphocarrier protein signature 43 58 2.1E-10 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like UA74_27730 fde8a1b0844bdd8e24e6af02afcd3ce5 421 Pfam PF13560 Helix-turn-helix domain 10 69 1.1E-10 T 12-10-2018 UA74_27730 fde8a1b0844bdd8e24e6af02afcd3ce5 421 SMART SM00530 13 68 3.1E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_27730 fde8a1b0844bdd8e24e6af02afcd3ce5 421 Gene3D G3DSA:1.25.40.10 180 402 7.8E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_27730 fde8a1b0844bdd8e24e6af02afcd3ce5 421 SUPERFAMILY SSF47413 11 64 3.66E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_27730 fde8a1b0844bdd8e24e6af02afcd3ce5 421 Gene3D G3DSA:1.10.260.40 2 83 2.2E-9 T 12-10-2018 UA74_16410 8aa0dfad22b6b699044c5d32ca7c0b68 381 Pfam PF07730 Histidine kinase 177 243 5.4E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_16410 8aa0dfad22b6b699044c5d32ca7c0b68 381 Gene3D G3DSA:3.30.565.10 254 377 2.9E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_16410 8aa0dfad22b6b699044c5d32ca7c0b68 381 SUPERFAMILY SSF55874 286 376 1.81E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_16615 88c4b6d409cbb94b7513cdbd6dbef270 230 Gene3D G3DSA:1.10.10.60 2 64 8.0E-18 T 12-10-2018 UA74_16615 88c4b6d409cbb94b7513cdbd6dbef270 230 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 72 210 2.0E-14 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_16615 88c4b6d409cbb94b7513cdbd6dbef270 230 Gene3D G3DSA:1.10.357.10 67 229 5.2E-24 T 12-10-2018 UA74_16615 88c4b6d409cbb94b7513cdbd6dbef270 230 SUPERFAMILY SSF48498 74 210 2.78E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_16615 88c4b6d409cbb94b7513cdbd6dbef270 230 SUPERFAMILY SSF46689 7 70 2.87E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_16615 88c4b6d409cbb94b7513cdbd6dbef270 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 53 3.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 SUPERFAMILY SSF55021 2 69 1.74E-8 T 12-10-2018 UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 SUPERFAMILY SSF56784 174 383 2.8E-49 T 12-10-2018 IPR036412 HAD-like superfamily UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 Gene3D G3DSA:1.10.150.210 186 246 7.3E-69 T 12-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 Gene3D G3DSA:3.30.70.260 86 172 2.2E-26 T 12-10-2018 UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 176 346 8.3E-28 T 12-10-2018 UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 Pfam PF12710 haloacid dehalogenase-like hydrolase 177 344 5.9E-25 T 12-10-2018 UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 162 378 2.8E-71 T 12-10-2018 UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 Gene3D G3DSA:3.40.50.1000 175 366 7.3E-69 T 12-10-2018 IPR023214 HAD superfamily UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 Pfam PF13740 ACT domain 1 72 1.9E-16 T 12-10-2018 UA74_06155 9e1395dce2634c657f3bb542000b82d1 403 Gene3D G3DSA:3.30.70.260 1 74 1.4E-11 T 12-10-2018 UA74_25260 160fb5de5d8f18d71ff7b5dca0a6b63d 245 Pfam PF02591 C4-type zinc ribbon domain 203 237 3.2E-10 T 12-10-2018 IPR003743 C4-type zinc ribbon domain UA74_15615 fdaa326949d1263c9105ae7b1920ab9a 711 Gene3D G3DSA:3.40.50.300 292 575 3.7E-38 T 12-10-2018 UA74_15615 fdaa326949d1263c9105ae7b1920ab9a 711 Pfam PF01580 FtsK/SpoIIIE family 348 513 1.2E-6 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_15615 fdaa326949d1263c9105ae7b1920ab9a 711 SUPERFAMILY SSF52540 283 541 7.26E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11900 1b7dfc638b1842507099f6ff77bbbdfd 301 SMART SM00342 228 300 0.0014 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_11900 1b7dfc638b1842507099f6ff77bbbdfd 301 SUPERFAMILY SSF52317 3 193 1.95E-42 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_11900 1b7dfc638b1842507099f6ff77bbbdfd 301 Gene3D G3DSA:3.40.50.880 1 212 1.0E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_11900 1b7dfc638b1842507099f6ff77bbbdfd 301 SUPERFAMILY SSF46689 212 262 7.83E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_11900 1b7dfc638b1842507099f6ff77bbbdfd 301 Gene3D G3DSA:1.10.10.60 213 300 2.7E-16 T 12-10-2018 UA74_11900 1b7dfc638b1842507099f6ff77bbbdfd 301 Pfam PF01965 DJ-1/PfpI family 3 172 4.4E-20 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UA74_11900 1b7dfc638b1842507099f6ff77bbbdfd 301 Pfam PF12833 Helix-turn-helix domain 234 296 1.6E-11 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_12630 822ae1f42a1d2a6d675f9da0b186466f 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 251 8.7E-33 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UA74_12630 822ae1f42a1d2a6d675f9da0b186466f 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 122 142 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 UA74_12630 822ae1f42a1d2a6d675f9da0b186466f 268 SUPERFAMILY SSF52096 16 257 2.7E-57 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_12630 822ae1f42a1d2a6d675f9da0b186466f 268 Gene3D G3DSA:3.90.226.10 12 266 2.7E-61 T 12-10-2018 UA74_22875 5e3a7eeaad1bd3271895c624badb01df 526 Gene3D G3DSA:1.20.1720.10 16 259 4.0E-41 T 12-10-2018 UA74_22875 5e3a7eeaad1bd3271895c624badb01df 526 Pfam PF07690 Major Facilitator Superfamily 24 411 8.6E-45 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_22875 5e3a7eeaad1bd3271895c624badb01df 526 SUPERFAMILY SSF103473 8 495 8.37E-60 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_22875 5e3a7eeaad1bd3271895c624badb01df 526 Gene3D G3DSA:1.20.1250.20 271 499 2.4E-15 T 12-10-2018 UA74_03165 b4bbd9b1a3cd9bc0205ed996a906b61c 212 Gene3D G3DSA:3.40.50.12740 1 209 4.2E-44 T 12-10-2018 UA74_03165 b4bbd9b1a3cd9bc0205ed996a906b61c 212 SMART SM00448 1 120 2.3E-9 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_03165 b4bbd9b1a3cd9bc0205ed996a906b61c 212 SMART SM00421 146 208 1.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03165 b4bbd9b1a3cd9bc0205ed996a906b61c 212 SUPERFAMILY SSF52172 2 171 1.19E-15 T 12-10-2018 IPR011006 CheY-like superfamily UA74_03165 b4bbd9b1a3cd9bc0205ed996a906b61c 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 193 2.5E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03165 b4bbd9b1a3cd9bc0205ed996a906b61c 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03165 b4bbd9b1a3cd9bc0205ed996a906b61c 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03165 b4bbd9b1a3cd9bc0205ed996a906b61c 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.1E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_03165 b4bbd9b1a3cd9bc0205ed996a906b61c 212 Pfam PF00072 Response regulator receiver domain 6 108 4.6E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_16600 8e041fe98375a0179e57b93e7f8610f7 219 SUPERFAMILY SSF46689 3 64 2.62E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_16600 8e041fe98375a0179e57b93e7f8610f7 219 SUPERFAMILY SSF48498 73 210 1.33E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_16600 8e041fe98375a0179e57b93e7f8610f7 219 Gene3D G3DSA:1.10.357.10 1 218 2.3E-38 T 12-10-2018 UA74_16600 8e041fe98375a0179e57b93e7f8610f7 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 3.2E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_10385 1eef6ddaf734004ca03a495a68f3a662 409 Pfam PF13439 Glycosyltransferase Family 4 21 197 5.7E-38 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_10385 1eef6ddaf734004ca03a495a68f3a662 409 Pfam PF00534 Glycosyl transferases group 1 207 369 6.5E-39 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_10385 1eef6ddaf734004ca03a495a68f3a662 409 Gene3D G3DSA:3.40.50.2000 5 388 2.2E-123 T 12-10-2018 UA74_10385 1eef6ddaf734004ca03a495a68f3a662 409 Gene3D G3DSA:3.40.50.2000 193 371 2.2E-123 T 12-10-2018 UA74_10385 1eef6ddaf734004ca03a495a68f3a662 409 SUPERFAMILY SSF53756 1 392 1.33E-96 T 12-10-2018 UA74_11625 e8b74ad3ec3a8a767ef8ad3a1b529110 252 Gene3D G3DSA:3.40.50.12500 18 249 2.4E-60 T 12-10-2018 UA74_11625 e8b74ad3ec3a8a767ef8ad3a1b529110 252 PIRSF PIRSF015736 14 248 2.1E-62 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase UA74_25040 1c5b39c00b345122ddd3baedec6b64bc 366 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 363 8.7E-129 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 UA74_25040 1c5b39c00b345122ddd3baedec6b64bc 366 Gene3D G3DSA:3.30.470.10 30 361 1.8E-133 T 12-10-2018 UA74_25040 1c5b39c00b345122ddd3baedec6b64bc 366 SUPERFAMILY SSF56752 10 363 4.45E-109 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 UA74_25040 1c5b39c00b345122ddd3baedec6b64bc 366 PIRSF PIRSF006468 5 365 1.8E-127 T 12-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 UA74_25040 1c5b39c00b345122ddd3baedec6b64bc 366 Pfam PF01063 Amino-transferase class IV 75 319 1.9E-27 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 UA74_25040 1c5b39c00b345122ddd3baedec6b64bc 366 Gene3D G3DSA:3.20.10.10 176 348 1.8E-133 T 12-10-2018 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 630 647 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SUPERFAMILY SSF52440 2 113 1.37E-42 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Gene3D G3DSA:2.40.50.100 607 675 7.2E-21 T 12-10-2018 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Gene3D G3DSA:3.30.470.130 1 451 1.4E-178 T 12-10-2018 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SUPERFAMILY SSF51230 603 673 7.98E-20 T 12-10-2018 IPR011053 Single hybrid motif UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SUPERFAMILY SSF51246 332 447 4.34E-36 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Pfam PF00364 Biotin-requiring enzyme 607 672 2.9E-15 T 12-10-2018 IPR000089 Biotin/lipoyl attachment UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SMART SM00878 337 443 6.3E-52 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 9.3E-71 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 3.4E-34 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 SUPERFAMILY SSF56059 83 344 5.13E-63 T 12-10-2018 UA74_26165 3412f8a9e3f4aa4e8fd80bc475cf84c6 683 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 6.5E-40 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 SUPERFAMILY SSF47819 609 687 3.71E-19 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:3.40.50.300 11 276 3.7E-75 T 12-10-2018 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:1.10.10.160 109 192 3.7E-75 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:1.10.486.10 412 469 5.7E-33 T 12-10-2018 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:1.10.150.80 617 687 1.3E-18 T 12-10-2018 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Pfam PF00570 HRDC domain 619 684 5.4E-18 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:3.40.50.300 283 387 8.4E-31 T 12-10-2018 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 SMART SM00341 615 690 3.8E-7 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Pfam PF13361 UvrD-like helicase C-terminal domain 437 545 2.4E-22 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Pfam PF13361 UvrD-like helicase C-terminal domain 280 402 3.2E-19 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:1.10.486.10 388 403 8.4E-31 T 12-10-2018 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 SUPERFAMILY SSF52540 9 567 2.13E-132 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 274 3.2E-47 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UA74_04830 0ed3c437f983de7fca89738327bb611d 692 Gene3D G3DSA:3.40.50.300 470 562 5.7E-33 T 12-10-2018 UA74_07650 3139c1deb040d67d852ded6c75b7599f 134 SMART SM00345 17 76 4.5E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_07650 3139c1deb040d67d852ded6c75b7599f 134 SUPERFAMILY SSF46785 6 80 7.26E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_07650 3139c1deb040d67d852ded6c75b7599f 134 Gene3D G3DSA:1.10.10.10 10 131 3.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_07650 3139c1deb040d67d852ded6c75b7599f 134 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 2.1E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_05510 5ea5f6e1c31fdb2f41394c0941ed97c5 241 Gene3D G3DSA:1.10.357.10 23 233 1.1E-54 T 12-10-2018 UA74_05510 5ea5f6e1c31fdb2f41394c0941ed97c5 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 1.6E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05510 5ea5f6e1c31fdb2f41394c0941ed97c5 241 SUPERFAMILY SSF46689 20 93 3.64E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 Gene3D G3DSA:3.30.70.2520 281 374 1.3E-34 T 12-10-2018 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 Gene3D G3DSA:3.30.465.10 70 279 1.1E-83 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 SUPERFAMILY SSF56176 5 174 1.38E-32 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 PIRSF PIRSF000136 3 237 1.8E-40 T 12-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 PIRSF PIRSF000136 278 412 1.2E-7 T 12-10-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 Gene3D G3DSA:3.30.70.2530 177 262 1.1E-83 T 12-10-2018 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 Gene3D G3DSA:3.30.43.10 2 66 1.5E-19 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 Gene3D G3DSA:1.10.45.10 375 411 4.7E-6 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 Pfam PF01565 FAD binding domain 19 145 1.2E-18 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UA74_14355 4b90e8e3aefa282cca89f01f38f5d7be 412 Pfam PF04030 D-arabinono-1,4-lactone oxidase 283 407 3.3E-20 T 12-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 SUPERFAMILY SSF117892 51 185 2.62E-41 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 75 96 2.4E-35 T 12-10-2018 IPR001972 Stomatin family GO:0016020 UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 130 153 2.4E-35 T 12-10-2018 IPR001972 Stomatin family GO:0016020 UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 27 49 2.4E-35 T 12-10-2018 IPR001972 Stomatin family GO:0016020 UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 110 127 2.4E-35 T 12-10-2018 IPR001972 Stomatin family GO:0016020 UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 173 194 2.4E-35 T 12-10-2018 IPR001972 Stomatin family GO:0016020 UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 PRINTS PR00721 Stomatin signature 154 172 2.4E-35 T 12-10-2018 IPR001972 Stomatin family GO:0016020 UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 ProSitePatterns PS01270 Band 7 protein family signature. 134 162 - T 12-10-2018 IPR018080 Band 7/stomatin-like, conserved site UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 Pfam PF01145 SPFH domain / Band 7 family 24 195 1.1E-34 T 12-10-2018 IPR001107 Band 7 domain UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 Gene3D G3DSA:3.30.479.30 48 180 1.3E-44 T 12-10-2018 UA74_11570 a6e6b80fef2f42bc7c87524d179ada63 418 SMART SM00244 20 178 1.8E-58 T 12-10-2018 IPR001107 Band 7 domain UA74_15750 b91d014d03f628b6cc6c4c7ebb791224 229 Pfam PF02585 GlcNAc-PI de-N-acetylase 9 131 1.3E-17 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_15750 b91d014d03f628b6cc6c4c7ebb791224 229 Gene3D G3DSA:3.40.50.10320 1 227 1.7E-40 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_15750 b91d014d03f628b6cc6c4c7ebb791224 229 SUPERFAMILY SSF102588 6 225 4.05E-38 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_11255 d91f18e0664101ca0c5bc8c86e4b4247 165 Gene3D G3DSA:1.10.10.10 24 141 6.7E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_11255 d91f18e0664101ca0c5bc8c86e4b4247 165 Pfam PF01638 HxlR-like helix-turn-helix 42 126 4.1E-27 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_11255 d91f18e0664101ca0c5bc8c86e4b4247 165 SUPERFAMILY SSF46785 34 142 9.27E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_17155 fe83126ba99bb3ba3766e98d1ed4ed02 254 Gene3D G3DSA:3.40.630.30 3 249 9.9E-22 T 12-10-2018 UA74_17155 fe83126ba99bb3ba3766e98d1ed4ed02 254 SUPERFAMILY SSF55729 46 242 5.68E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_17155 fe83126ba99bb3ba3766e98d1ed4ed02 254 Pfam PF00583 Acetyltransferase (GNAT) family 167 233 3.1E-5 T 12-10-2018 IPR000182 GNAT domain UA74_17535 dd025ed0081e95aba136634374fbb5aa 468 SUPERFAMILY SSF53756 1 344 7.33E-60 T 12-10-2018 UA74_17535 dd025ed0081e95aba136634374fbb5aa 468 Gene3D G3DSA:3.40.50.11450 1 231 1.9E-104 T 12-10-2018 UA74_17535 dd025ed0081e95aba136634374fbb5aa 468 Gene3D G3DSA:3.40.50.11450 449 461 2.3E-10 T 12-10-2018 UA74_17535 dd025ed0081e95aba136634374fbb5aa 468 SUPERFAMILY SSF53756 398 461 6.73E-7 T 12-10-2018 UA74_17535 dd025ed0081e95aba136634374fbb5aa 468 Gene3D G3DSA:3.40.50.2000 232 346 1.9E-104 T 12-10-2018 UA74_17535 dd025ed0081e95aba136634374fbb5aa 468 Gene3D G3DSA:3.40.50.2000 392 448 2.3E-10 T 12-10-2018 UA74_17535 dd025ed0081e95aba136634374fbb5aa 468 Pfam PF06722 Protein of unknown function (DUF1205) 210 305 3.2E-21 T 12-10-2018 IPR010610 Domain of unknown function DUF1205 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 155 5.4E-61 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 Gene3D G3DSA:3.40.50.620 1 157 9.2E-56 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 57 1.4E-18 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 2.0E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 2.0E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 2.0E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 2.0E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 2.0E-49 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 Pfam PF01467 Cytidylyltransferase-like 5 132 2.4E-19 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 155 9.0E-4 T 12-10-2018 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 SUPERFAMILY SSF52374 1 154 1.1E-44 T 12-10-2018 UA74_25615 d265a7d6308f0eafe5a68b409e61afc7 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 34.571 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UA74_13860 985f6a1d82b7b258ad75124fa8a49da0 279 SUPERFAMILY SSF52540 28 242 3.0E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13860 985f6a1d82b7b258ad75124fa8a49da0 279 SMART SM00382 55 236 2.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13860 985f6a1d82b7b258ad75124fa8a49da0 279 Pfam PF00005 ABC transporter 46 185 1.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13860 985f6a1d82b7b258ad75124fa8a49da0 279 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_13860 985f6a1d82b7b258ad75124fa8a49da0 279 Gene3D G3DSA:3.40.50.300 26 269 6.4E-68 T 12-10-2018 UA74_13350 c53abc18609b1c40e3c7ac47474113b6 234 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 123 136 - T 12-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_13350 c53abc18609b1c40e3c7ac47474113b6 234 Gene3D G3DSA:3.20.20.70 1 210 6.8E-58 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_13350 c53abc18609b1c40e3c7ac47474113b6 234 Pfam PF01081 KDPG and KHG aldolase 5 184 3.1E-36 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_13350 c53abc18609b1c40e3c7ac47474113b6 234 SUPERFAMILY SSF51569 2 203 1.34E-48 T 12-10-2018 UA74_09365 4b43058cdc8e6685d136f01ce31f5b39 114 Pfam PF13806 Rieske-like [2Fe-2S] domain 8 111 5.8E-36 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 UA74_09365 4b43058cdc8e6685d136f01ce31f5b39 114 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 8 111 2.0E-34 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 UA74_09365 4b43058cdc8e6685d136f01ce31f5b39 114 SUPERFAMILY SSF50022 7 113 1.23E-34 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_09365 4b43058cdc8e6685d136f01ce31f5b39 114 Gene3D G3DSA:2.102.10.10 4 113 6.9E-39 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_19675 d457c46ae9353a8825dfdc6262ba8454 188 Gene3D G3DSA:3.30.530.20 26 187 7.2E-37 T 12-10-2018 IPR023393 START-like domain superfamily UA74_19675 d457c46ae9353a8825dfdc6262ba8454 188 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 52 182 1.0E-17 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_19675 d457c46ae9353a8825dfdc6262ba8454 188 SUPERFAMILY SSF55961 40 184 3.46E-35 T 12-10-2018 UA74_28580 cfa6075a16ff492f0a970d5f6082914a 364 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 299 319 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 UA74_28580 cfa6075a16ff492f0a970d5f6082914a 364 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 UA74_28580 cfa6075a16ff492f0a970d5f6082914a 364 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 9 363 3.8E-127 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_28580 cfa6075a16ff492f0a970d5f6082914a 364 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 343 46.309 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 UA74_28580 cfa6075a16ff492f0a970d5f6082914a 364 Gene3D G3DSA:3.20.20.70 1 364 2.1E-122 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_28580 cfa6075a16ff492f0a970d5f6082914a 364 Pfam PF01180 Dihydroorotate dehydrogenase 50 345 2.2E-92 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 UA74_28580 cfa6075a16ff492f0a970d5f6082914a 364 SUPERFAMILY SSF51395 1 361 1.28E-96 T 12-10-2018 UA74_10925 d25b629deafac0a4d252785f3fa076c0 335 Gene3D G3DSA:1.10.10.10 6 86 2.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10925 d25b629deafac0a4d252785f3fa076c0 335 Pfam PF00891 O-methyltransferase 103 318 1.9E-39 T 12-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_10925 d25b629deafac0a4d252785f3fa076c0 335 SUPERFAMILY SSF53335 97 331 9.4E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_10925 d25b629deafac0a4d252785f3fa076c0 335 Gene3D G3DSA:3.40.50.150 94 335 4.2E-55 T 12-10-2018 UA74_10925 d25b629deafac0a4d252785f3fa076c0 335 SUPERFAMILY SSF46785 14 83 4.52E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_10925 d25b629deafac0a4d252785f3fa076c0 335 Pfam PF16864 Dimerisation domain 14 93 5.0E-14 T 12-10-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain UA74_10925 d25b629deafac0a4d252785f3fa076c0 335 PIRSF PIRSF005739 2 333 1.6E-28 T 12-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_23970 8b0522321baa86f100f6035a65122838 281 Gene3D G3DSA:1.10.3720.10 82 278 6.9E-21 T 12-10-2018 IPR035906 MetI-like superfamily UA74_23970 8b0522321baa86f100f6035a65122838 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 276 4.6E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_23970 8b0522321baa86f100f6035a65122838 281 SUPERFAMILY SSF161098 82 276 5.49E-25 T 12-10-2018 IPR035906 MetI-like superfamily UA74_24920 398a0689b713e89f33327b3a1e9efdf2 229 Pfam PF00510 Cytochrome c oxidase subunit III 48 227 3.7E-25 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_24920 398a0689b713e89f33327b3a1e9efdf2 229 SUPERFAMILY SSF81452 37 227 2.22E-58 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_24920 398a0689b713e89f33327b3a1e9efdf2 229 Gene3D G3DSA:1.20.120.80 45 229 5.4E-53 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 SUPERFAMILY SSF48264 25 372 4.45E-53 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00385 P450 superfamily signature 235 252 3.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00385 P450 superfamily signature 332 341 3.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00385 P450 superfamily signature 341 352 3.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00385 P450 superfamily signature 276 287 3.0E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 143 159 7.6E-15 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 341 352 7.6E-15 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 160 175 7.6E-15 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 96 107 7.6E-15 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 272 283 7.6E-15 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 PRINTS PR00359 B-class P450 signature 332 341 7.6E-15 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 Gene3D G3DSA:1.10.630.10 5 395 2.4E-67 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_04310 6c974b9ca5e7e1cbbf341a335cfcc76a 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_05930 09ff0117d198376298e3e846a27be887 245 Gene3D G3DSA:3.10.450.200 135 237 2.6E-5 T 12-10-2018 IPR037178 Colicin D, C-terminal domain superfamily GO:0004540 UA74_05930 09ff0117d198376298e3e846a27be887 245 SUPERFAMILY SSF51294 1 133 2.88E-17 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_05930 09ff0117d198376298e3e846a27be887 245 Gene3D G3DSA:2.170.16.10 1 134 1.3E-37 T 12-10-2018 UA74_05930 09ff0117d198376298e3e846a27be887 245 SMART SM00306 1 92 0.0082 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_05930 09ff0117d198376298e3e846a27be887 245 Pfam PF07591 Pretoxin HINT domain 6 135 2.6E-19 T 12-10-2018 UA74_13005 7ca64c20749f1eab6e57793bed15ca1d 517 Gene3D G3DSA:2.30.40.10 1 457 9.2E-85 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_13005 7ca64c20749f1eab6e57793bed15ca1d 517 SUPERFAMILY SSF51338 2 463 1.62E-5 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_13005 7ca64c20749f1eab6e57793bed15ca1d 517 Pfam PF07969 Amidohydrolase family 27 507 7.9E-82 T 12-10-2018 IPR013108 Amidohydrolase 3 UA74_13005 7ca64c20749f1eab6e57793bed15ca1d 517 SUPERFAMILY SSF51556 37 440 1.88E-32 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_13005 7ca64c20749f1eab6e57793bed15ca1d 517 Gene3D G3DSA:3.10.310.70 56 164 9.2E-85 T 12-10-2018 UA74_13005 7ca64c20749f1eab6e57793bed15ca1d 517 Gene3D G3DSA:3.20.20.140 38 444 9.2E-85 T 12-10-2018 UA74_11295 9362b2a2d67a243981ecec3f763bd879 260 Gene3D G3DSA:1.10.10.60 10 89 4.0E-24 T 12-10-2018 UA74_11295 9362b2a2d67a243981ecec3f763bd879 260 SUPERFAMILY SSF46689 28 93 9.48E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_11295 9362b2a2d67a243981ecec3f763bd879 260 Gene3D G3DSA:1.10.357.10 95 255 8.9E-38 T 12-10-2018 UA74_11295 9362b2a2d67a243981ecec3f763bd879 260 SUPERFAMILY SSF48498 105 256 1.1E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_11295 9362b2a2d67a243981ecec3f763bd879 260 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 83 2.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_11295 9362b2a2d67a243981ecec3f763bd879 260 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 101 252 1.4E-18 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_01940 9530e537d47d01778630ca9188e549c1 191 Pfam PF13302 Acetyltransferase (GNAT) domain 18 155 1.3E-20 T 12-10-2018 IPR000182 GNAT domain UA74_01940 9530e537d47d01778630ca9188e549c1 191 Gene3D G3DSA:3.40.630.30 3 188 7.1E-48 T 12-10-2018 UA74_01940 9530e537d47d01778630ca9188e549c1 191 SUPERFAMILY SSF55729 10 179 1.77E-41 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_10050 315ec2ab37e0b69523249c809e23cc76 271 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_10050 315ec2ab37e0b69523249c809e23cc76 271 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 262 31.237 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_10050 315ec2ab37e0b69523249c809e23cc76 271 SUPERFAMILY SSF51366 1 239 1.04E-76 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UA74_10050 315ec2ab37e0b69523249c809e23cc76 271 Pfam PF00290 Tryptophan synthase alpha chain 8 254 1.4E-68 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_10050 315ec2ab37e0b69523249c809e23cc76 271 Gene3D G3DSA:3.20.20.70 1 269 2.4E-86 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_10050 315ec2ab37e0b69523249c809e23cc76 271 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 242 2.7E-63 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_21495 b129e435ff17371da60b14a9e3074171 675 SMART SM00387 570 666 8.1E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_21495 b129e435ff17371da60b14a9e3074171 675 Pfam PF07730 Histidine kinase 461 527 1.1E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_21495 b129e435ff17371da60b14a9e3074171 675 Gene3D G3DSA:3.30.565.10 538 665 2.8E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_21495 b129e435ff17371da60b14a9e3074171 675 SUPERFAMILY SSF55874 551 664 1.96E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 PRINTS PR00359 B-class P450 signature 165 180 6.8E-10 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 PRINTS PR00359 B-class P450 signature 307 334 6.8E-10 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 PRINTS PR00359 B-class P450 signature 290 301 6.8E-10 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 PRINTS PR00359 B-class P450 signature 148 164 6.8E-10 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 SUPERFAMILY SSF48264 42 337 1.44E-41 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 414 423 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 Gene3D G3DSA:1.10.630.10 389 474 4.7E-18 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 Gene3D G3DSA:1.10.630.10 17 340 5.6E-56 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 SUPERFAMILY SSF48264 396 471 7.33E-16 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 Pfam PF00067 Cytochrome P450 397 438 2.1E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_09155 c9eac44adcbd3535bc436e28198859dc 475 Pfam PF00067 Cytochrome P450 289 337 2.1E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_29855 dd1076a1573031e4f693c63e0209f1ad 305 Pfam PF13845 Septum formation 77 283 1.5E-37 T 12-10-2018 IPR026004 Septum formation-related domain UA74_15790 6b9e0bf8c3957a839a153e8a07c03a82 355 Gene3D G3DSA:1.20.970.10 6 71 1.1E-21 T 12-10-2018 UA74_15790 6b9e0bf8c3957a839a153e8a07c03a82 355 Pfam PF02885 Glycosyl transferase family, helical bundle domain 10 69 1.3E-14 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_15790 6b9e0bf8c3957a839a153e8a07c03a82 355 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 13 346 3.7E-103 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UA74_15790 6b9e0bf8c3957a839a153e8a07c03a82 355 SUPERFAMILY SSF47648 7 74 3.79E-15 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_15790 6b9e0bf8c3957a839a153e8a07c03a82 355 SUPERFAMILY SSF52418 81 348 3.79E-76 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_15790 6b9e0bf8c3957a839a153e8a07c03a82 355 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 10 347 32.815 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UA74_15790 6b9e0bf8c3957a839a153e8a07c03a82 355 Gene3D G3DSA:3.40.1030.10 79 353 2.7E-94 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_15790 6b9e0bf8c3957a839a153e8a07c03a82 355 Pfam PF00591 Glycosyl transferase family, a/b domain 80 337 4.7E-79 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UA74_13980 9876b1e6b1a05e97277ea724e27fcdf4 187 Gene3D G3DSA:1.20.120.450 1 133 9.6E-12 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_13980 9876b1e6b1a05e97277ea724e27fcdf4 187 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 7 185 6.1E-48 T 12-10-2018 IPR017520 Conserved hypothetical protein CHP03086 UA74_13980 9876b1e6b1a05e97277ea724e27fcdf4 187 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 129 5.4E-14 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_13980 9876b1e6b1a05e97277ea724e27fcdf4 187 SUPERFAMILY SSF109854 2 135 1.45E-22 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_13980 9876b1e6b1a05e97277ea724e27fcdf4 187 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 185 2.2E-21 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_17865 70d18772c80dcb6fb3bdd8fb9ec0f43c 429 Pfam PF13416 Bacterial extracellular solute-binding protein 55 353 2.5E-21 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_17865 70d18772c80dcb6fb3bdd8fb9ec0f43c 429 SUPERFAMILY SSF53850 38 418 1.19E-53 T 12-10-2018 UA74_17865 70d18772c80dcb6fb3bdd8fb9ec0f43c 429 Gene3D G3DSA:3.40.190.10 21 424 1.3E-58 T 12-10-2018 UA74_26475 265d0009e230789d048c0cea466f6dff 301 Gene3D G3DSA:2.50.20.20 57 288 6.8E-7 T 12-10-2018 UA74_26475 265d0009e230789d048c0cea466f6dff 301 SUPERFAMILY SSF89392 66 288 1.22E-9 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX UA74_22485 af23f8bd35aab1210e42a5fa78fe71ba 316 SUPERFAMILY SSF161098 89 296 1.26E-20 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22485 af23f8bd35aab1210e42a5fa78fe71ba 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 2.0E-35 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_22485 af23f8bd35aab1210e42a5fa78fe71ba 316 Gene3D G3DSA:1.10.3720.10 80 315 2.6E-22 T 12-10-2018 IPR035906 MetI-like superfamily UA74_12415 504fcf841dbefece226f6856fd26c7f3 374 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 17 361 5.2E-77 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 UA74_12415 504fcf841dbefece226f6856fd26c7f3 374 TIGRFAM TIGR00876 tal_mycobact: transaldolase 13 360 2.2E-134 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_12415 504fcf841dbefece226f6856fd26c7f3 374 Gene3D G3DSA:3.20.20.70 5 367 1.0E-152 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_12415 504fcf841dbefece226f6856fd26c7f3 374 ProSitePatterns PS01054 Transaldolase signature 1. 43 51 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 UA74_12415 504fcf841dbefece226f6856fd26c7f3 374 Hamap MF_00493 Transaldolase [tal]. 1 372 152.684 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_12415 504fcf841dbefece226f6856fd26c7f3 374 PIRSF PIRSF036915 1 374 1.1E-162 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UA74_12415 504fcf841dbefece226f6856fd26c7f3 374 SUPERFAMILY SSF51569 8 365 4.27E-74 T 12-10-2018 UA74_26125 5109f09d2febabe5354af5b752700b6c 242 SMART SM00346 23 110 1.1E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_26125 5109f09d2febabe5354af5b752700b6c 242 Gene3D G3DSA:3.30.450.40 94 168 1.3E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_26125 5109f09d2febabe5354af5b752700b6c 242 Pfam PF01614 Bacterial transcriptional regulator 173 216 2.3E-4 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_26125 5109f09d2febabe5354af5b752700b6c 242 Gene3D G3DSA:3.30.450.40 169 241 3.3E-10 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_26125 5109f09d2febabe5354af5b752700b6c 242 Pfam PF09339 IclR helix-turn-helix domain 26 74 2.1E-7 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_26125 5109f09d2febabe5354af5b752700b6c 242 Gene3D G3DSA:1.10.10.10 9 89 2.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26125 5109f09d2febabe5354af5b752700b6c 242 SUPERFAMILY SSF55781 97 238 1.24E-21 T 12-10-2018 UA74_26125 5109f09d2febabe5354af5b752700b6c 242 SUPERFAMILY SSF46785 24 95 1.08E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14870 cb8529a2f8441e6e29e3f0ded953c793 116 SUPERFAMILY SSF54184 20 82 1.57E-7 T 12-10-2018 UA74_14870 cb8529a2f8441e6e29e3f0ded953c793 116 SMART SM00740 16 84 0.0017 T 12-10-2018 IPR005543 PASTA domain UA74_14870 cb8529a2f8441e6e29e3f0ded953c793 116 Gene3D G3DSA:3.30.10.20 18 82 2.3E-9 T 12-10-2018 UA74_14870 cb8529a2f8441e6e29e3f0ded953c793 116 Pfam PF03793 PASTA domain 20 82 5.2E-10 T 12-10-2018 IPR005543 PASTA domain UA74_25710 c38bdb32aeaca8351a3bc87bf2f88728 223 SUPERFAMILY SSF48371 6 221 1.99E-60 T 12-10-2018 IPR016024 Armadillo-type fold UA74_25710 c38bdb32aeaca8351a3bc87bf2f88728 223 Pfam PF08713 DNA alkylation repair enzyme 10 197 2.4E-20 T 12-10-2018 IPR014825 DNA alkylation repair enzyme UA74_22245 c8a173a110d9396f3356733cec68ab09 171 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 168 1.3E-14 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal UA74_22245 c8a173a110d9396f3356733cec68ab09 171 SUPERFAMILY SSF81296 31 170 4.9E-33 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_22245 c8a173a110d9396f3356733cec68ab09 171 Gene3D G3DSA:2.70.50.50 31 171 8.3E-49 T 12-10-2018 UA74_24990 3b3911e172aca8ad3c52017b89d540c4 311 Pfam PF00294 pfkB family carbohydrate kinase 14 281 5.9E-41 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_24990 3b3911e172aca8ad3c52017b89d540c4 311 Gene3D G3DSA:3.40.1190.20 1 306 2.6E-73 T 12-10-2018 IPR029056 Ribokinase-like UA74_24990 3b3911e172aca8ad3c52017b89d540c4 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 33 57 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_24990 3b3911e172aca8ad3c52017b89d540c4 311 SUPERFAMILY SSF53613 10 281 5.14E-49 T 12-10-2018 IPR029056 Ribokinase-like UA74_12165 e82e48c06c648f99d10d6e383e487471 373 Pfam PF00557 Metallopeptidase family M24 153 356 5.8E-62 T 12-10-2018 IPR000994 Peptidase M24 UA74_12165 e82e48c06c648f99d10d6e383e487471 373 Gene3D G3DSA:3.90.230.10 144 373 4.6E-77 T 12-10-2018 UA74_12165 e82e48c06c648f99d10d6e383e487471 373 Gene3D G3DSA:3.40.350.10 3 143 2.0E-26 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UA74_12165 e82e48c06c648f99d10d6e383e487471 373 SUPERFAMILY SSF53092 10 144 2.44E-21 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UA74_12165 e82e48c06c648f99d10d6e383e487471 373 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 303 315 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site UA74_12165 e82e48c06c648f99d10d6e383e487471 373 Pfam PF01321 Creatinase/Prolidase N-terminal domain 12 145 8.1E-21 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 UA74_12165 e82e48c06c648f99d10d6e383e487471 373 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 243 7.1E-8 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_12165 e82e48c06c648f99d10d6e383e487471 373 PRINTS PR00599 Methionine aminopeptidase-1 signature 205 218 7.1E-8 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_12165 e82e48c06c648f99d10d6e383e487471 373 PRINTS PR00599 Methionine aminopeptidase-1 signature 325 337 7.1E-8 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_12165 e82e48c06c648f99d10d6e383e487471 373 SUPERFAMILY SSF55920 106 367 2.88E-73 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like UA74_07480 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:1.20.1580.10 588 626 1.2E-104 T 12-10-2018 UA74_07480 48e98221a46861e65114cd0890032cc7 801 SUPERFAMILY SSF52540 23 459 1.9E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07480 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:1.10.8.280 189 298 9.9E-153 T 12-10-2018 UA74_07480 48e98221a46861e65114cd0890032cc7 801 SUPERFAMILY SSF52540 500 772 6.55E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07480 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:3.40.50.300 501 795 1.2E-104 T 12-10-2018 UA74_07480 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:1.20.1580.10 109 376 9.9E-153 T 12-10-2018 UA74_07480 48e98221a46861e65114cd0890032cc7 801 Pfam PF00005 ABC transporter 507 719 2.5E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_07480 48e98221a46861e65114cd0890032cc7 801 Gene3D G3DSA:3.40.50.300 23 477 9.9E-153 T 12-10-2018 UA74_16705 8d5173f2ba83cf4d3eb20e073aa1eb18 278 Gene3D G3DSA:3.40.50.300 13 265 2.1E-72 T 12-10-2018 UA74_16705 8d5173f2ba83cf4d3eb20e073aa1eb18 278 SMART SM00382 39 226 1.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_16705 8d5173f2ba83cf4d3eb20e073aa1eb18 278 Pfam PF00005 ABC transporter 30 179 4.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_16705 8d5173f2ba83cf4d3eb20e073aa1eb18 278 SUPERFAMILY SSF52540 13 241 2.47E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22460 db2be757abc77f9e4fd16ce5268b60dd 1366 SUPERFAMILY SSF52540 247 409 1.61E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22460 db2be757abc77f9e4fd16ce5268b60dd 1366 Pfam PF13365 Trypsin-like peptidase domain 24 174 6.3E-9 T 12-10-2018 UA74_22460 db2be757abc77f9e4fd16ce5268b60dd 1366 Gene3D G3DSA:1.25.40.10 1143 1345 2.6E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_22460 db2be757abc77f9e4fd16ce5268b60dd 1366 Gene3D G3DSA:1.25.40.10 945 1137 2.8E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_22460 db2be757abc77f9e4fd16ce5268b60dd 1366 Gene3D G3DSA:2.40.10.120 2 193 7.5E-7 T 12-10-2018 UA74_22460 db2be757abc77f9e4fd16ce5268b60dd 1366 SUPERFAMILY SSF48452 947 1273 4.41E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_22460 db2be757abc77f9e4fd16ce5268b60dd 1366 Gene3D G3DSA:3.40.50.300 241 359 2.2E-8 T 12-10-2018 UA74_22460 db2be757abc77f9e4fd16ce5268b60dd 1366 SUPERFAMILY SSF50494 14 177 1.59E-14 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_02410 c9d7af6a3c23581ebb509383ed79b23a 463 SUPERFAMILY SSF52540 211 425 5.94E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_02410 c9d7af6a3c23581ebb509383ed79b23a 463 Gene3D G3DSA:3.40.50.300 212 435 1.6E-33 T 12-10-2018 UA74_02410 c9d7af6a3c23581ebb509383ed79b23a 463 Pfam PF13614 AAA domain 212 356 4.4E-11 T 12-10-2018 IPR025669 AAA domain UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 Gene3D G3DSA:3.40.980.10 195 346 4.7E-124 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 SUPERFAMILY SSF63882 22 196 3.27E-48 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 Pfam PF03453 MoeA N-terminal region (domain I and II) 24 187 3.3E-39 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 Gene3D G3DSA:2.170.190.11 65 161 4.7E-124 T 12-10-2018 UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 Pfam PF03454 MoeA C-terminal region (domain IV) 355 419 3.2E-14 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 SUPERFAMILY SSF53218 197 340 4.58E-40 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 Pfam PF00994 Probable molybdopterin binding domain 201 334 2.0E-24 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 Gene3D G3DSA:3.90.105.10 43 194 4.7E-124 T 12-10-2018 UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 SMART SM00852 200 336 4.5E-40 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 197 332 8.1E-32 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 SUPERFAMILY SSF63867 354 420 7.46E-15 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28565 f1994b58bcaab8e32f4f56525217f1dd 433 Gene3D G3DSA:2.40.340.10 347 414 4.7E-124 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_14555 3cb4dd03b4853710fa68442738464f2f 341 SUPERFAMILY SSF53686 28 294 3.8E-42 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_14555 3cb4dd03b4853710fa68442738464f2f 341 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 30 280 6.1E-28 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_14555 3cb4dd03b4853710fa68442738464f2f 341 Gene3D G3DSA:3.40.50.1100 135 290 5.3E-43 T 12-10-2018 UA74_14555 3cb4dd03b4853710fa68442738464f2f 341 Gene3D G3DSA:3.40.50.1100 29 134 5.3E-43 T 12-10-2018 UA74_00695 f0ed4cff4af179c7d8af1ce314abe6f6 315 Pfam PF00535 Glycosyl transferase family 2 28 189 3.2E-14 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_00695 f0ed4cff4af179c7d8af1ce314abe6f6 315 SUPERFAMILY SSF53448 25 288 6.11E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_00695 f0ed4cff4af179c7d8af1ce314abe6f6 315 Gene3D G3DSA:3.90.550.10 12 236 1.0E-19 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_17255 e66679e89d6231d863d3cab134f37549 748 Gene3D G3DSA:3.40.50.300 172 402 3.3E-10 T 12-10-2018 UA74_17255 e66679e89d6231d863d3cab134f37549 748 Pfam PF13538 UvrD-like helicase C-terminal domain 677 726 3.4E-8 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain UA74_17255 e66679e89d6231d863d3cab134f37549 748 Gene3D G3DSA:3.40.50.300 468 599 1.6E-6 T 12-10-2018 UA74_17255 e66679e89d6231d863d3cab134f37549 748 Gene3D G3DSA:3.40.50.300 665 742 1.2E-8 T 12-10-2018 UA74_17255 e66679e89d6231d863d3cab134f37549 748 SUPERFAMILY SSF52540 174 730 7.31E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_17255 e66679e89d6231d863d3cab134f37549 748 Pfam PF13245 AAA domain 186 568 1.6E-11 T 12-10-2018 UA74_26395 ba8c457bef18f5ed6fafa8e7590b97d8 201 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 14 199 2.0E-49 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_26395 ba8c457bef18f5ed6fafa8e7590b97d8 201 PIRSF PIRSF000709 10 175 2.5E-10 T 12-10-2018 UA74_26395 ba8c457bef18f5ed6fafa8e7590b97d8 201 SUPERFAMILY SSF53254 14 199 2.49E-50 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_26395 ba8c457bef18f5ed6fafa8e7590b97d8 201 Gene3D G3DSA:3.40.50.1240 11 201 1.0E-55 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_26395 ba8c457bef18f5ed6fafa8e7590b97d8 201 SMART SM00855 13 161 4.3E-20 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00149 Fumarate lyase superfamily signature 276 303 1.0E-32 T 12-10-2018 IPR000362 Fumarate lyase family UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00149 Fumarate lyase superfamily signature 322 338 1.0E-32 T 12-10-2018 IPR000362 Fumarate lyase family UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00149 Fumarate lyase superfamily signature 185 203 1.0E-32 T 12-10-2018 IPR000362 Fumarate lyase family UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 1.0E-32 T 12-10-2018 IPR000362 Fumarate lyase family UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 Gene3D G3DSA:1.20.200.10 144 412 1.6E-109 T 12-10-2018 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00145 Argininosuccinate lyase family signature 180 200 1.4E-6 T 12-10-2018 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00145 Argininosuccinate lyase family signature 138 160 1.4E-6 T 12-10-2018 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 PRINTS PR00145 Argininosuccinate lyase family signature 322 338 1.4E-6 T 12-10-2018 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 Gene3D G3DSA:1.10.40.30 413 469 2.8E-25 T 12-10-2018 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 Hamap MF_00743 Fumarate hydratase class II [fumC]. 15 472 80.766 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 ProSitePatterns PS00163 Fumarate lyases signature. 322 331 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 SUPERFAMILY SSF48557 15 470 1.27E-141 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 Gene3D G3DSA:1.10.275.10 16 143 6.0E-49 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 Pfam PF10415 Fumarase C C-terminus 413 471 6.9E-22 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UA74_04120 c077734e7bf3b7fcecadd9b340bad0fc 474 Pfam PF00206 Lyase 23 347 3.8E-97 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal UA74_27955 4f805937f29e8d6c4b9c7dac97b54df7 534 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 22 533 4.3E-228 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 UA74_27955 4f805937f29e8d6c4b9c7dac97b54df7 534 Gene3D G3DSA:3.20.20.360 4 412 1.4E-183 T 12-10-2018 UA74_27955 4f805937f29e8d6c4b9c7dac97b54df7 534 Pfam PF01274 Malate synthase 12 531 5.9E-189 T 12-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 UA74_27955 4f805937f29e8d6c4b9c7dac97b54df7 534 PIRSF PIRSF001363 1 534 2.4E-230 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 UA74_27955 4f805937f29e8d6c4b9c7dac97b54df7 534 Gene3D G3DSA:1.20.1220.12 416 533 4.9E-39 T 12-10-2018 UA74_27955 4f805937f29e8d6c4b9c7dac97b54df7 534 SUPERFAMILY SSF51645 7 532 4.84E-180 T 12-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 UA74_27955 4f805937f29e8d6c4b9c7dac97b54df7 534 ProSitePatterns PS00510 Malate synthase signature. 266 281 - T 12-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 UA74_28755 5cae00b23ea297810b758988824b8e9b 310 SUPERFAMILY SSF81606 14 267 5.49E-5 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_28755 5cae00b23ea297810b758988824b8e9b 310 Pfam PF13672 Protein phosphatase 2C 26 279 2.3E-5 T 12-10-2018 UA74_13215 a7fd01047e41184a62ea0199daed4368 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.0E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13215 a7fd01047e41184a62ea0199daed4368 299 SUPERFAMILY SSF46785 6 114 4.96E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_13215 a7fd01047e41184a62ea0199daed4368 299 Gene3D G3DSA:3.40.190.10 96 284 2.0E-36 T 12-10-2018 UA74_13215 a7fd01047e41184a62ea0199daed4368 299 Pfam PF03466 LysR substrate binding domain 92 284 1.0E-42 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_13215 a7fd01047e41184a62ea0199daed4368 299 Gene3D G3DSA:1.10.10.10 5 93 2.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13215 a7fd01047e41184a62ea0199daed4368 299 Gene3D G3DSA:3.40.190.10 168 273 2.0E-36 T 12-10-2018 UA74_13215 a7fd01047e41184a62ea0199daed4368 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13215 a7fd01047e41184a62ea0199daed4368 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13215 a7fd01047e41184a62ea0199daed4368 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13215 a7fd01047e41184a62ea0199daed4368 299 SUPERFAMILY SSF53850 95 284 4.98E-37 T 12-10-2018 UA74_19115 41ccc72ba47950e6889750041f5b0100 379 SMART SM00220 11 268 9.9E-35 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_19115 41ccc72ba47950e6889750041f5b0100 379 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_19115 41ccc72ba47950e6889750041f5b0100 379 SUPERFAMILY SSF56112 7 262 6.97E-58 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_19115 41ccc72ba47950e6889750041f5b0100 379 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 39 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_19115 41ccc72ba47950e6889750041f5b0100 379 Gene3D G3DSA:1.10.510.10 85 269 3.3E-36 T 12-10-2018 UA74_19115 41ccc72ba47950e6889750041f5b0100 379 Gene3D G3DSA:3.30.200.20 3 84 1.9E-17 T 12-10-2018 UA74_19115 41ccc72ba47950e6889750041f5b0100 379 Pfam PF00069 Protein kinase domain 11 260 3.0E-33 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 Gene3D G3DSA:1.10.10.10 2 71 9.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 SMART SM00345 7 66 1.2E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 SUPERFAMILY SSF46785 5 70 7.26E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 SMART SM00895 93 215 2.1E-17 T 12-10-2018 IPR011711 GntR, C-terminal UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 66 4.0E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 Gene3D G3DSA:1.20.120.530 88 225 5.7E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 SUPERFAMILY SSF48008 89 222 3.4E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 6.0E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 6.0E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_01875 51ce7660f9d1ccb1138bf580e8b9acfb 226 Pfam PF07729 FCD domain 93 214 2.2E-21 T 12-10-2018 IPR011711 GntR, C-terminal UA74_17710 32c416bd8e513e78b7a8a089993078de 239 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 45 219 3.3E-16 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 UA74_17710 32c416bd8e513e78b7a8a089993078de 239 Gene3D G3DSA:1.10.520.40 26 234 7.2E-32 T 12-10-2018 IPR038287 Cse2 superfamily UA74_17710 32c416bd8e513e78b7a8a089993078de 239 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 48 218 3.9E-25 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 SUPERFAMILY SSF52518 357 557 6.66E-58 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 1.6E-39 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 SUPERFAMILY SSF52467 181 351 8.0E-43 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 Gene3D G3DSA:3.40.50.970 2 174 2.3E-52 T 12-10-2018 UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 SUPERFAMILY SSF52518 2 173 1.16E-40 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 Gene3D G3DSA:3.40.50.1220 178 332 3.0E-47 T 12-10-2018 UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 525 3.8E-38 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 Gene3D G3DSA:3.40.50.970 349 573 7.0E-65 T 12-10-2018 UA74_19610 0c484ced6e3d0cbee40911dff1c16d38 577 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 317 4.4E-31 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UA74_01720 7a070705d11cdf483c8a92b2a1ac9e9e 510 Pfam PF01580 FtsK/SpoIIIE family 237 424 3.3E-15 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_01720 7a070705d11cdf483c8a92b2a1ac9e9e 510 SUPERFAMILY SSF52540 212 476 1.03E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01720 7a070705d11cdf483c8a92b2a1ac9e9e 510 Gene3D G3DSA:3.40.50.300 217 487 6.1E-42 T 12-10-2018 UA74_28550 e25b18b59745e47596cea49c3de84833 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_28550 e25b18b59745e47596cea49c3de84833 539 Gene3D G3DSA:1.10.560.10 7 519 2.0E-218 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily UA74_28550 e25b18b59745e47596cea49c3de84833 539 Gene3D G3DSA:3.50.7.10 190 370 2.0E-218 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily UA74_28550 e25b18b59745e47596cea49c3de84833 539 SUPERFAMILY SSF54849 136 201 2.75E-25 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily UA74_28550 e25b18b59745e47596cea49c3de84833 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 2.3E-246 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_28550 e25b18b59745e47596cea49c3de84833 539 Hamap MF_00600 60 kDa chaperonin [groL]. 1 537 40.953 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_28550 e25b18b59745e47596cea49c3de84833 539 SUPERFAMILY SSF52029 184 374 5.23E-80 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily UA74_28550 e25b18b59745e47596cea49c3de84833 539 Gene3D G3DSA:3.30.260.10 135 408 2.0E-218 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily UA74_28550 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 266 289 2.5E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_28550 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 396 417 2.5E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_28550 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 26 52 2.5E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_28550 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 82 109 2.5E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_28550 e25b18b59745e47596cea49c3de84833 539 PRINTS PR00298 60kDa chaperonin signature 348 373 2.5E-70 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UA74_28550 e25b18b59745e47596cea49c3de84833 539 SUPERFAMILY SSF48592 6 519 1.92E-72 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily UA74_28550 e25b18b59745e47596cea49c3de84833 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 2.2E-93 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 UA74_30145 a006cbc5109fba6af2654116f0f94bf4 129 SUPERFAMILY SSF102546 2 129 2.49E-36 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 UA74_30145 a006cbc5109fba6af2654116f0f94bf4 129 Pfam PF05025 RbsD / FucU transport protein family 2 127 1.4E-39 T 12-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 UA74_30145 a006cbc5109fba6af2654116f0f94bf4 129 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 129 29.16 T 12-10-2018 IPR023064 D-ribose pyranase GO:0016872 UA74_30145 a006cbc5109fba6af2654116f0f94bf4 129 Gene3D G3DSA:3.40.1650.10 9 125 4.4E-30 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 UA74_01765 5f18e684dda52bd6aa1e76960ba732e1 364 Gene3D G3DSA:3.40.50.1980 151 244 7.1E-15 T 12-10-2018 UA74_01765 5f18e684dda52bd6aa1e76960ba732e1 364 Gene3D G3DSA:3.40.50.2300 278 362 3.6E-7 T 12-10-2018 UA74_01765 5f18e684dda52bd6aa1e76960ba732e1 364 SUPERFAMILY SSF53807 40 362 1.08E-61 T 12-10-2018 UA74_01765 5f18e684dda52bd6aa1e76960ba732e1 364 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 361 1.9E-51 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 UA74_01765 5f18e684dda52bd6aa1e76960ba732e1 364 Gene3D G3DSA:3.40.50.1980 39 145 1.6E-21 T 12-10-2018 UA74_08295 7affd8a65a3f8e1a7f07d825b8a9473c 326 Gene3D G3DSA:1.20.272.10 201 325 5.8E-16 T 12-10-2018 UA74_08295 7affd8a65a3f8e1a7f07d825b8a9473c 326 SUPERFAMILY SSF48019 203 317 1.12E-11 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 UA74_08295 7affd8a65a3f8e1a7f07d825b8a9473c 326 Pfam PF06144 DNA polymerase III, delta subunit 13 174 8.0E-7 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 UA74_08295 7affd8a65a3f8e1a7f07d825b8a9473c 326 Gene3D G3DSA:3.40.50.300 5 124 1.7E-10 T 12-10-2018 UA74_08295 7affd8a65a3f8e1a7f07d825b8a9473c 326 SUPERFAMILY SSF52540 7 182 7.17E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08295 7affd8a65a3f8e1a7f07d825b8a9473c 326 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 9 317 1.1E-28 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 UA74_02305 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 396 491 5.9E-7 T 12-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 UA74_02305 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 Gene3D G3DSA:2.60.40.650 401 504 4.9E-26 T 12-10-2018 UA74_02305 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 SUPERFAMILY SSF81296 395 503 2.87E-25 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_02305 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 Gene3D G3DSA:3.90.420.10 186 400 4.6E-51 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 UA74_02305 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 Pfam PF00174 Oxidoreductase molybdopterin binding domain 232 384 2.0E-38 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 UA74_02305 65f83aff89c7a0dbdf8e3c0af2e79d6c 506 SUPERFAMILY SSF56524 214 401 8.5E-58 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 UA74_09535 2fe5fe89a4bc497401e2db7e02283d76 204 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_09535 2fe5fe89a4bc497401e2db7e02283d76 204 Pfam PF01066 CDP-alcohol phosphatidyltransferase 20 90 4.2E-13 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_09535 2fe5fe89a4bc497401e2db7e02283d76 204 Gene3D G3DSA:1.20.120.1760 19 190 3.2E-8 T 12-10-2018 UA74_09535 2fe5fe89a4bc497401e2db7e02283d76 204 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 20 189 1.0E-41 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 UA74_09535 2fe5fe89a4bc497401e2db7e02283d76 204 PIRSF PIRSF000847 17 199 1.8E-45 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 UA74_29685 ba3bb7bb749bb7540316c1824d98de51 97 SMART SM00883 1 85 1.7E-23 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_29685 ba3bb7bb749bb7540316c1824d98de51 97 Pfam PF00166 Chaperonin 10 Kd subunit 1 84 4.1E-17 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UA74_29685 ba3bb7bb749bb7540316c1824d98de51 97 SUPERFAMILY SSF50129 2 85 3.39E-18 T 12-10-2018 IPR011032 GroES-like superfamily UA74_29685 ba3bb7bb749bb7540316c1824d98de51 97 Gene3D G3DSA:2.30.33.40 1 85 2.1E-13 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 UA74_09165 70855866c95ae1efddd70e301218f796 425 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 174 385 7.2E-49 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 UA74_09165 70855866c95ae1efddd70e301218f796 425 SUPERFAMILY SSF53790 172 407 5.1E-71 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 UA74_09165 70855866c95ae1efddd70e301218f796 425 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 174 407 2.2E-81 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UA74_09165 70855866c95ae1efddd70e301218f796 425 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 19 140 1.6E-19 T 12-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UA74_09165 70855866c95ae1efddd70e301218f796 425 Pfam PF13241 Putative NAD(P)-binding 19 124 5.5E-19 T 12-10-2018 UA74_09165 70855866c95ae1efddd70e301218f796 425 Gene3D G3DSA:3.40.1010.10 171 287 2.3E-38 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 UA74_09165 70855866c95ae1efddd70e301218f796 425 Gene3D G3DSA:3.30.950.10 288 422 5.9E-43 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 UA74_09165 70855866c95ae1efddd70e301218f796 425 PIRSF PIRSF036426 147 424 8.0E-94 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UA74_09165 70855866c95ae1efddd70e301218f796 425 PIRSF PIRSF036426 11 171 8.9E-28 T 12-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UA74_09165 70855866c95ae1efddd70e301218f796 425 Gene3D G3DSA:3.40.50.720 15 139 4.8E-28 T 12-10-2018 UA74_09165 70855866c95ae1efddd70e301218f796 425 SUPERFAMILY SSF51735 19 115 3.15E-13 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_29430 389be387d69d736e0dbff13a9286ddbd 385 Pfam PF07690 Major Facilitator Superfamily 4 301 2.3E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_29430 389be387d69d736e0dbff13a9286ddbd 385 SUPERFAMILY SSF103473 2 377 4.19E-45 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_29430 389be387d69d736e0dbff13a9286ddbd 385 Gene3D G3DSA:1.20.1250.20 1 370 3.7E-39 T 12-10-2018 UA74_10425 a864879a924ec0281bdbcecffd171c1a 457 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 325 389 6.5E-15 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_10425 a864879a924ec0281bdbcecffd171c1a 457 SUPERFAMILY SSF53613 1 285 3.59E-26 T 12-10-2018 IPR029056 Ribokinase-like UA74_10425 a864879a924ec0281bdbcecffd171c1a 457 Pfam PF01467 Cytidylyltransferase-like 327 418 5.0E-14 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UA74_10425 a864879a924ec0281bdbcecffd171c1a 457 Gene3D G3DSA:3.40.50.620 310 455 2.5E-31 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_10425 a864879a924ec0281bdbcecffd171c1a 457 SUPERFAMILY SSF52374 324 449 8.73E-22 T 12-10-2018 UA74_10425 a864879a924ec0281bdbcecffd171c1a 457 Pfam PF00294 pfkB family carbohydrate kinase 170 288 3.5E-10 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_10425 a864879a924ec0281bdbcecffd171c1a 457 Gene3D G3DSA:3.40.1190.20 1 292 2.6E-59 T 12-10-2018 IPR029056 Ribokinase-like UA74_12755 f5a863d7cd38b635963e8402193f81ef 343 SUPERFAMILY SSF48576 8 321 4.64E-68 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_12755 f5a863d7cd38b635963e8402193f81ef 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 209 221 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site UA74_12755 f5a863d7cd38b635963e8402193f81ef 343 Pfam PF00348 Polyprenyl synthetase 38 275 1.0E-52 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 UA74_12755 f5a863d7cd38b635963e8402193f81ef 343 Gene3D G3DSA:1.10.600.10 2 329 8.2E-79 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 SMART SM00354 2 72 8.8E-24 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 Gene3D G3DSA:3.40.50.2300 169 299 4.0E-68 T 12-10-2018 UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 SUPERFAMILY SSF47413 3 56 6.66E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 Gene3D G3DSA:1.10.260.40 1 58 8.9E-20 T 12-10-2018 UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 SUPERFAMILY SSF53822 62 341 1.04E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.4E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.4E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 Gene3D G3DSA:3.40.50.2300 64 314 4.0E-68 T 12-10-2018 UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 Pfam PF13377 Periplasmic binding protein-like domain 178 338 7.0E-32 T 12-10-2018 UA74_23575 70080cfa6324b5eca057a14fef933d0a 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 5.4E-17 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_07345 e5f9ea005bb5c2d977178688442e2939 314 Gene3D G3DSA:1.10.3720.10 25 305 2.9E-54 T 12-10-2018 IPR035906 MetI-like superfamily UA74_07345 e5f9ea005bb5c2d977178688442e2939 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 307 4.8E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_07345 e5f9ea005bb5c2d977178688442e2939 314 SUPERFAMILY SSF161098 30 314 6.13E-49 T 12-10-2018 IPR035906 MetI-like superfamily UA74_23680 198520f56347219b147172db9a5b2f71 429 Pfam PF13393 Histidyl-tRNA synthetase 10 341 3.6E-47 T 12-10-2018 UA74_23680 198520f56347219b147172db9a5b2f71 429 SUPERFAMILY SSF55681 7 347 1.9E-68 T 12-10-2018 UA74_23680 198520f56347219b147172db9a5b2f71 429 Gene3D G3DSA:3.30.930.10 4 347 4.8E-96 T 12-10-2018 UA74_23680 198520f56347219b147172db9a5b2f71 429 PIRSF PIRSF001549 2 427 2.1E-95 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 UA74_23680 198520f56347219b147172db9a5b2f71 429 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 411 6.7E-89 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 UA74_18505 69234109509d28a0152cac9cb8897efe 242 Pfam PF12796 Ankyrin repeats (3 copies) 104 194 6.9E-14 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain UA74_18505 69234109509d28a0152cac9cb8897efe 242 SUPERFAMILY SSF48403 104 232 8.43E-24 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily UA74_18505 69234109509d28a0152cac9cb8897efe 242 PRINTS PR01415 Ankyrin repeat signature 130 145 2.7E-7 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_18505 69234109509d28a0152cac9cb8897efe 242 PRINTS PR01415 Ankyrin repeat signature 181 195 2.7E-7 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_18505 69234109509d28a0152cac9cb8897efe 242 SMART SM00248 129 158 0.11 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_18505 69234109509d28a0152cac9cb8897efe 242 SMART SM00248 207 237 0.033 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_18505 69234109509d28a0152cac9cb8897efe 242 SMART SM00248 165 194 1.0E-4 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_18505 69234109509d28a0152cac9cb8897efe 242 Gene3D G3DSA:1.25.40.20 89 237 6.5E-30 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily UA74_24795 ae7f71241854411822ac7a21834b439c 1546 SUPERFAMILY SSF63825 758 978 1.36E-5 T 12-10-2018 UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Gene3D G3DSA:3.90.930.1 522 678 9.7E-11 T 12-10-2018 UA74_24795 ae7f71241854411822ac7a21834b439c 1546 PRINTS PR00394 RHS protein signature 1217 1237 2.6E-9 T 12-10-2018 IPR001826 RHS protein UA74_24795 ae7f71241854411822ac7a21834b439c 1546 PRINTS PR00394 RHS protein signature 1162 1182 2.6E-9 T 12-10-2018 IPR001826 RHS protein UA74_24795 ae7f71241854411822ac7a21834b439c 1546 PRINTS PR00394 RHS protein signature 1240 1259 2.6E-9 T 12-10-2018 IPR001826 RHS protein UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Gene3D G3DSA:2.180.10.10 728 1272 1.8E-34 T 12-10-2018 UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1198 1272 1.6E-20 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 UA74_24795 ae7f71241854411822ac7a21834b439c 1546 SUPERFAMILY SSF140453 83 155 4.32E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1076 1111 4.4E-7 T 12-10-2018 IPR006530 YD repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 864 902 2.6E-7 T 12-10-2018 IPR006530 YD repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 780 820 1.8E-4 T 12-10-2018 IPR006530 YD repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 613 653 2.9E-6 T 12-10-2018 IPR006530 YD repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 633 672 5.6E-5 T 12-10-2018 IPR006530 YD repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 550 585 1.2E-4 T 12-10-2018 IPR006530 YD repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 822 861 8.1E-7 T 12-10-2018 IPR006530 YD repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 527 566 1.2E-7 T 12-10-2018 IPR006530 YD repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1001 1027 7.4E-4 T 12-10-2018 IPR006530 YD repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 SUPERFAMILY SSF69304 531 678 6.8E-5 T 12-10-2018 UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Pfam PF05593 RHS Repeat 1079 1105 8.5E-6 T 12-10-2018 IPR031325 RHS repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Pfam PF05593 RHS Repeat 548 584 4.0E-7 T 12-10-2018 IPR031325 RHS repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Pfam PF05593 RHS Repeat 827 858 2.1E-6 T 12-10-2018 IPR031325 RHS repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Pfam PF05593 RHS Repeat 864 899 2.6E-6 T 12-10-2018 IPR031325 RHS repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Pfam PF05593 RHS Repeat 1001 1028 4.8E-7 T 12-10-2018 IPR031325 RHS repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Pfam PF05593 RHS Repeat 843 879 1.5E-5 T 12-10-2018 IPR031325 RHS repeat UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Gene3D G3DSA:1.10.287.1060 78 169 8.8E-6 T 12-10-2018 UA74_24795 ae7f71241854411822ac7a21834b439c 1546 Pfam PF03527 RHS protein 1172 1201 7.8E-7 T 12-10-2018 IPR001826 RHS protein UA74_29130 65b27d5be93846290605af099b98d99c 265 Pfam PF11209 Protein of unknown function (DUF2993) 17 253 8.7E-42 T 12-10-2018 IPR021373 Protein of unknown function DUF2993 UA74_14785 c5c6e3c5cdd9f0fb6ed18545c261ef3b 342 SUPERFAMILY SSF53474 74 310 1.5E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_14785 c5c6e3c5cdd9f0fb6ed18545c261ef3b 342 Pfam PF10503 Esterase PHB depolymerase 79 194 1.1E-9 T 12-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 UA74_14785 c5c6e3c5cdd9f0fb6ed18545c261ef3b 342 Gene3D G3DSA:3.40.50.1820 37 324 1.4E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26880 7cc2b445c51f3ae7d4b9890d9caf2ead 142 Pfam PF03795 YCII-related domain 1 114 1.3E-26 T 12-10-2018 IPR005545 YCII-related UA74_26880 7cc2b445c51f3ae7d4b9890d9caf2ead 142 Gene3D G3DSA:3.30.70.1060 1 118 3.2E-36 T 12-10-2018 UA74_26880 7cc2b445c51f3ae7d4b9890d9caf2ead 142 SUPERFAMILY SSF54909 1 118 3.93E-37 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_09335 ac440d5473a5d746f29bffc80cdc9e7c 445 Pfam PF07690 Major Facilitator Superfamily 19 287 3.3E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_09335 ac440d5473a5d746f29bffc80cdc9e7c 445 SUPERFAMILY SSF103473 5 413 2.62E-54 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_09335 ac440d5473a5d746f29bffc80cdc9e7c 445 Gene3D G3DSA:1.20.1250.20 1 415 6.4E-51 T 12-10-2018 UA74_12750 e6e718d83369c352b8a8cffe037dfcc3 646 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 9 291 3.4E-94 T 12-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 UA74_12750 e6e718d83369c352b8a8cffe037dfcc3 646 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 3 627 4.4E-197 T 12-10-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 UA74_12750 e6e718d83369c352b8a8cffe037dfcc3 646 SUPERFAMILY SSF48239 302 626 1.1E-96 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UA74_12750 e6e718d83369c352b8a8cffe037dfcc3 646 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 7 626 3.6E-158 T 12-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 UA74_12750 e6e718d83369c352b8a8cffe037dfcc3 646 Gene3D G3DSA:1.50.10.20 29 303 3.3E-209 T 12-10-2018 UA74_12750 e6e718d83369c352b8a8cffe037dfcc3 646 Gene3D G3DSA:1.50.10.20 11 624 3.3E-209 T 12-10-2018 UA74_12750 e6e718d83369c352b8a8cffe037dfcc3 646 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 306 626 2.3E-121 T 12-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 UA74_12750 e6e718d83369c352b8a8cffe037dfcc3 646 SUPERFAMILY SSF48239 33 288 3.66E-52 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UA74_01540 e7033ff808b6e33ad00e43cf768de2f3 184 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 178 6.6E-67 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 UA74_01540 e7033ff808b6e33ad00e43cf768de2f3 184 SUPERFAMILY SSF53271 3 182 1.05E-52 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_01540 e7033ff808b6e33ad00e43cf768de2f3 184 Gene3D G3DSA:3.40.50.2020 1 183 5.0E-66 T 12-10-2018 UA74_01540 e7033ff808b6e33ad00e43cf768de2f3 184 Pfam PF00156 Phosphoribosyl transferase domain 18 164 4.9E-23 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 SMART SM00495 485 530 2.1E-16 T 12-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 Gene3D G3DSA:3.20.20.80 57 453 2.1E-143 T 12-10-2018 UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 SUPERFAMILY SSF51445 52 449 1.15E-88 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 SUPERFAMILY SSF51055 482 533 3.34E-15 T 12-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 ProSitePatterns PS01095 Chitinases family 18 active site. 212 220 - T 12-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 SMART SM00636 54 444 3.2E-121 T 12-10-2018 IPR011583 Chitinase II GO:0008061 UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 SUPERFAMILY SSF54556 350 416 1.5E-11 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 Gene3D G3DSA:2.10.10.20 482 533 5.6E-18 T 12-10-2018 UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 Gene3D G3DSA:3.10.50.10 358 425 2.1E-143 T 12-10-2018 IPR029070 Chitinase insertion domain superfamily UA74_27250 be5a3b90631c3d4b165cb3350af9a1ae 533 Pfam PF00704 Glycosyl hydrolases family 18 56 444 4.1E-82 T 12-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 UA74_02390 2ef5d6cf3d2018627054d220b4c5fdff 521 SUPERFAMILY SSF56112 11 261 1.33E-65 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_02390 2ef5d6cf3d2018627054d220b4c5fdff 521 Pfam PF00069 Protein kinase domain 15 261 2.4E-40 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_02390 2ef5d6cf3d2018627054d220b4c5fdff 521 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_02390 2ef5d6cf3d2018627054d220b4c5fdff 521 Gene3D G3DSA:1.10.510.10 91 293 4.9E-43 T 12-10-2018 UA74_02390 2ef5d6cf3d2018627054d220b4c5fdff 521 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_02390 2ef5d6cf3d2018627054d220b4c5fdff 521 SMART SM00220 15 272 1.7E-46 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_02390 2ef5d6cf3d2018627054d220b4c5fdff 521 Gene3D G3DSA:3.30.200.20 5 90 9.5E-20 T 12-10-2018 UA74_29880 3b140d2da6a2419641be8a14acf427ca 550 Pfam PF03806 AbgT putative transporter family 283 547 9.0E-84 T 12-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 UA74_29880 3b140d2da6a2419641be8a14acf427ca 550 Pfam PF03806 AbgT putative transporter family 15 244 1.1E-60 T 12-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 UA74_05535 700f26c21aa83cce1a584850bd2cd68d 156 SUPERFAMILY SSF46785 17 144 5.54E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_05535 700f26c21aa83cce1a584850bd2cd68d 156 SMART SM00347 30 142 5.6E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05535 700f26c21aa83cce1a584850bd2cd68d 156 Pfam PF12802 MarR family 46 97 2.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_05535 700f26c21aa83cce1a584850bd2cd68d 156 Gene3D G3DSA:1.10.10.10 2 146 3.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_05785 11fb4fea7a1da7384e5b72833bdd0a27 392 Pfam PF12698 ABC-2 family transporter protein 24 384 2.5E-30 T 12-10-2018 UA74_25770 8b90a9ae2c09049970fc48eb9c52f8bb 293 Pfam PF00005 ABC transporter 20 157 6.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_25770 8b90a9ae2c09049970fc48eb9c52f8bb 293 SUPERFAMILY SSF52540 3 223 1.33E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25770 8b90a9ae2c09049970fc48eb9c52f8bb 293 SMART SM00382 29 205 1.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_25770 8b90a9ae2c09049970fc48eb9c52f8bb 293 Gene3D G3DSA:3.40.50.300 1 238 9.0E-58 T 12-10-2018 UA74_04035 f76cfd748f7c541471b2ff6cd05bdeb1 521 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 38 501 1.3E-196 T 12-10-2018 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial UA74_04035 f76cfd748f7c541471b2ff6cd05bdeb1 521 Pfam PF13489 Methyltransferase domain 308 469 7.6E-10 T 12-10-2018 UA74_04035 f76cfd748f7c541471b2ff6cd05bdeb1 521 Gene3D G3DSA:3.30.1610.20 37 267 7.0E-102 T 12-10-2018 IPR038546 Hen1, N-terminal domain superfamily UA74_04035 f76cfd748f7c541471b2ff6cd05bdeb1 521 SUPERFAMILY SSF53335 307 475 3.17E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_04035 f76cfd748f7c541471b2ff6cd05bdeb1 521 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 37 279 3.4E-110 T 12-10-2018 IPR024740 Hen1, N-terminal UA74_04035 f76cfd748f7c541471b2ff6cd05bdeb1 521 Gene3D G3DSA:3.40.50.150 297 507 1.8E-62 T 12-10-2018 UA74_20560 4b834415e153999467b373330e684e7f 258 Pfam PF13091 PLD-like domain 109 235 5.7E-13 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 UA74_20560 4b834415e153999467b373330e684e7f 258 SUPERFAMILY SSF56024 102 239 4.93E-17 T 12-10-2018 UA74_20560 4b834415e153999467b373330e684e7f 258 Gene3D G3DSA:3.30.870.10 84 246 1.6E-17 T 12-10-2018 UA74_18200 fa5da9ffee8fdccf93a415f1b7726217 171 Gene3D G3DSA:1.20.120.1630 1 169 5.6E-21 T 12-10-2018 UA74_18200 fa5da9ffee8fdccf93a415f1b7726217 171 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 75 167 3.1E-32 T 12-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 UA74_03875 e0a5717d3c950a0d3b11075a1ec919ac 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 78 92 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_03875 e0a5717d3c950a0d3b11075a1ec919ac 361 Gene3D G3DSA:3.40.50.720 174 304 5.3E-74 T 12-10-2018 UA74_03875 e0a5717d3c950a0d3b11075a1ec919ac 361 Pfam PF00107 Zinc-binding dehydrogenase 198 319 2.0E-15 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_03875 e0a5717d3c950a0d3b11075a1ec919ac 361 SUPERFAMILY SSF51735 164 325 2.27E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_03875 e0a5717d3c950a0d3b11075a1ec919ac 361 Gene3D G3DSA:3.90.180.10 35 348 5.3E-74 T 12-10-2018 UA74_03875 e0a5717d3c950a0d3b11075a1ec919ac 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 43 150 1.6E-26 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_03875 e0a5717d3c950a0d3b11075a1ec919ac 361 SUPERFAMILY SSF50129 15 195 1.19E-39 T 12-10-2018 IPR011032 GroES-like superfamily UA74_22250 86b9052ff6c1b362c63bd27e40b8bd15 265 SMART SM00954 56 179 4.7E-44 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 UA74_22250 86b9052ff6c1b362c63bd27e40b8bd15 265 Gene3D G3DSA:3.30.460.10 8 161 4.8E-49 T 12-10-2018 UA74_22250 86b9052ff6c1b362c63bd27e40b8bd15 265 SUPERFAMILY SSF81301 18 213 6.38E-57 T 12-10-2018 UA74_22250 86b9052ff6c1b362c63bd27e40b8bd15 265 Pfam PF04607 Region found in RelA / SpoT proteins 56 177 1.4E-35 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 UA74_22250 86b9052ff6c1b362c63bd27e40b8bd15 265 Gene3D G3DSA:1.10.287.860 162 224 2.4E-20 T 12-10-2018 UA74_09675 9c7ca392b2c1ef668b6623b73c57fbec 255 Gene3D G3DSA:3.30.1360.40 52 125 2.0E-18 T 12-10-2018 UA74_09675 9c7ca392b2c1ef668b6623b73c57fbec 255 SMART SM00796 53 243 6.5E-86 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D UA74_09675 9c7ca392b2c1ef668b6623b73c57fbec 255 SUPERFAMILY SSF50891 132 254 1.37E-40 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily UA74_09675 9c7ca392b2c1ef668b6623b73c57fbec 255 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 55 243 4.9E-65 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D UA74_09675 9c7ca392b2c1ef668b6623b73c57fbec 255 SUPERFAMILY SSF160467 56 136 1.14E-11 T 12-10-2018 UA74_09675 9c7ca392b2c1ef668b6623b73c57fbec 255 Gene3D G3DSA:2.40.100.10 126 255 8.2E-54 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily UA74_12175 f0f0484b733f2d4f97f43f55fe369141 139 SUPERFAMILY SSF48013 3 130 2.09E-38 T 12-10-2018 IPR035926 NusB-like superfamily UA74_12175 f0f0484b733f2d4f97f43f55fe369141 139 Pfam PF01029 NusB family 6 130 1.5E-34 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UA74_12175 f0f0484b733f2d4f97f43f55fe369141 139 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 3 130 8.9E-40 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 UA74_12175 f0f0484b733f2d4f97f43f55fe369141 139 Gene3D G3DSA:1.10.940.10 1 128 2.2E-43 T 12-10-2018 IPR035926 NusB-like superfamily UA74_12175 f0f0484b733f2d4f97f43f55fe369141 139 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 2 133 22.951 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 UA74_14365 128636ce11016ae68f4c2a48feb166db 390 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 39 121 1.6E-9 T 12-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain UA74_14365 128636ce11016ae68f4c2a48feb166db 390 PIRSF PIRSF035009 1 384 5.3E-133 T 12-10-2018 IPR017035 Uncharacterised conserved protein UCP035009, HsdR, All3000-type UA74_10205 2c434718387e6e58986b955e78b1b7ca 313 Gene3D G3DSA:3.40.190.290 94 300 7.1E-29 T 12-10-2018 UA74_10205 2c434718387e6e58986b955e78b1b7ca 313 Pfam PF03466 LysR substrate binding domain 96 293 1.1E-28 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_10205 2c434718387e6e58986b955e78b1b7ca 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 4.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_10205 2c434718387e6e58986b955e78b1b7ca 313 SUPERFAMILY SSF46785 2 96 3.63E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_10205 2c434718387e6e58986b955e78b1b7ca 313 SUPERFAMILY SSF53850 94 294 8.24E-30 T 12-10-2018 UA74_10205 2c434718387e6e58986b955e78b1b7ca 313 Gene3D G3DSA:1.10.10.10 1 83 1.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19220 23016696f079236469ff55c479d15bfd 352 Pfam PF01757 Acyltransferase family 9 317 5.9E-19 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_05765 d0f7fc6b2e5fab1c0471cacec5dae810 260 Pfam PF00561 alpha/beta hydrolase fold 19 239 8.0E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05765 d0f7fc6b2e5fab1c0471cacec5dae810 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 7.5E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05765 d0f7fc6b2e5fab1c0471cacec5dae810 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 7.5E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05765 d0f7fc6b2e5fab1c0471cacec5dae810 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 198 212 7.5E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05765 d0f7fc6b2e5fab1c0471cacec5dae810 260 Gene3D G3DSA:3.40.50.1820 5 255 7.4E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05765 d0f7fc6b2e5fab1c0471cacec5dae810 260 SUPERFAMILY SSF53474 10 253 2.92E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07230 6c62b9de2c8c6581890e2c276a77b3c4 639 SUPERFAMILY SSF51703 76 633 3.92E-185 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_07230 6c62b9de2c8c6581890e2c276a77b3c4 639 Pfam PF01642 Methylmalonyl-CoA mutase 101 631 1.9E-207 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_07230 6c62b9de2c8c6581890e2c276a77b3c4 639 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 100 638 6.2E-195 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_07230 6c62b9de2c8c6581890e2c276a77b3c4 639 Gene3D G3DSA:3.20.20.240 58 639 2.9E-220 T 12-10-2018 UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 TIGRFAM TIGR03971 SDR_subfam_1: SDR family mycofactocin-dependent oxidoreductase 4 266 1.4E-104 T 12-10-2018 IPR023985 Mycofactocin-dependent oxidoreductase UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 4.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 4.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 4.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 4.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 4.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 SUPERFAMILY SSF51735 2 265 4.12E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 Gene3D G3DSA:3.40.50.720 2 267 9.1E-72 T 12-10-2018 UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 9.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 9.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 9.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05175 48fe4ef25d3a16044c63fc609af6d7b5 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 264 9.0E-48 T 12-10-2018 UA74_22680 ba15ebe0ac806153ce5652a4a773cf30 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 5.1E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_22680 ba15ebe0ac806153ce5652a4a773cf30 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 5.1E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_22680 ba15ebe0ac806153ce5652a4a773cf30 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 5.1E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_22680 ba15ebe0ac806153ce5652a4a773cf30 112 SUPERFAMILY SSF46785 7 101 1.18E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22680 ba15ebe0ac806153ce5652a4a773cf30 112 Pfam PF12840 Helix-turn-helix domain 10 69 4.0E-15 T 12-10-2018 UA74_22680 ba15ebe0ac806153ce5652a4a773cf30 112 SMART SM00418 11 89 9.9E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_22680 ba15ebe0ac806153ce5652a4a773cf30 112 Gene3D G3DSA:1.10.10.10 2 111 2.8E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_09145 0d92199a020d1feaa78f62020981f32b 385 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 225 234 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 UA74_09145 0d92199a020d1feaa78f62020981f32b 385 Gene3D G3DSA:3.90.1150.10 32 362 1.2E-113 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_09145 0d92199a020d1feaa78f62020981f32b 385 Pfam PF00155 Aminotransferase class I and II 29 369 1.0E-55 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_09145 0d92199a020d1feaa78f62020981f32b 385 SUPERFAMILY SSF53383 20 371 1.34E-92 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_09145 0d92199a020d1feaa78f62020981f32b 385 Gene3D G3DSA:3.40.640.10 46 276 1.2E-113 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_11430 5b0707ddd376ed9058731f8f9bd0348a 490 Pfam PF00854 POT family 93 453 2.1E-73 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 UA74_11430 5b0707ddd376ed9058731f8f9bd0348a 490 SUPERFAMILY SSF103473 6 480 7.06E-28 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_11430 5b0707ddd376ed9058731f8f9bd0348a 490 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 154 166 - T 12-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 UA74_11430 5b0707ddd376ed9058731f8f9bd0348a 490 Gene3D G3DSA:1.20.1250.20 2 490 7.1E-141 T 12-10-2018 UA74_11430 5b0707ddd376ed9058731f8f9bd0348a 490 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 11 485 1.1E-138 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 UA74_10660 678e3816aac61cceb6c91934148a623f 288 SUPERFAMILY SSF53335 44 270 7.81E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_10660 678e3816aac61cceb6c91934148a623f 288 Gene3D G3DSA:3.40.50.150 78 283 8.4E-39 T 12-10-2018 UA74_10660 678e3816aac61cceb6c91934148a623f 288 Pfam PF08241 Methyltransferase domain 91 186 1.3E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 Gene3D G3DSA:3.30.420.40 169 349 9.5E-86 T 12-10-2018 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 SUPERFAMILY SSF53067 178 364 2.32E-33 T 12-10-2018 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 505 644 3.0E-21 T 12-10-2018 IPR023840 Type VII secretion system Rv3446c UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 PRINTS PR00301 70kDa heat shock protein signature 186 196 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 PRINTS PR00301 70kDa heat shock protein signature 348 368 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 PRINTS PR00301 70kDa heat shock protein signature 13 26 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 PRINTS PR00301 70kDa heat shock protein signature 64 72 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 PRINTS PR00301 70kDa heat shock protein signature 318 334 2.2E-9 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 180 193 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 Gene3D G3DSA:3.90.640.10 212 299 9.5E-86 T 12-10-2018 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 321 335 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 Pfam PF00012 Hsp70 protein 105 367 3.5E-26 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 SUPERFAMILY SSF53067 12 162 7.45E-20 T 12-10-2018 UA74_28060 32b66de877bfae3d4f7f219236ab6b21 646 Gene3D G3DSA:3.30.420.40 15 359 9.5E-86 T 12-10-2018 UA74_14360 6502982558d33e779c56a6293e058d4f 279 Gene3D G3DSA:3.40.710.10 9 278 1.7E-74 T 12-10-2018 UA74_14360 6502982558d33e779c56a6293e058d4f 279 SUPERFAMILY SSF56601 14 271 3.26E-53 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_14360 6502982558d33e779c56a6293e058d4f 279 Pfam PF00144 Beta-lactamase 40 256 1.3E-30 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_21795 3feb9687f890ecd102948ae9b9aeff74 282 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 98 1.4E-10 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 UA74_03740 b0ceff6e441d050437157875ea54b58f 179 Pfam PF04417 Protein of unknown function (DUF501) 35 156 2.5E-36 T 12-10-2018 IPR007511 Protein of unknown function DUF501 UA74_28390 3d3c89f49e9310275444d336914096de 261 SUPERFAMILY SSF54506 1 259 1.54E-72 T 12-10-2018 UA74_28390 3d3c89f49e9310275444d336914096de 261 PIRSF PIRSF016184 1 261 2.1E-49 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_28390 3d3c89f49e9310275444d336914096de 261 Gene3D G3DSA:3.10.310.10 114 249 1.9E-79 T 12-10-2018 UA74_28390 3d3c89f49e9310275444d336914096de 261 Gene3D G3DSA:3.10.310.10 6 253 1.9E-79 T 12-10-2018 UA74_28390 3d3c89f49e9310275444d336914096de 261 Pfam PF02567 Phenazine biosynthesis-like protein 8 257 2.8E-58 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_28390 3d3c89f49e9310275444d336914096de 261 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 85 1.0E-23 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UA74_05900 7994835896d254f0bacf09306d86c2b8 467 Pfam PF05195 Aminopeptidase P, N-terminal domain 40 158 5.7E-18 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 UA74_05900 7994835896d254f0bacf09306d86c2b8 467 SMART SM01011 37 174 8.9E-33 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 UA74_05900 7994835896d254f0bacf09306d86c2b8 467 SUPERFAMILY SSF55920 197 463 3.66E-55 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like UA74_05900 7994835896d254f0bacf09306d86c2b8 467 Gene3D G3DSA:3.90.230.10 196 466 9.9E-67 T 12-10-2018 UA74_05900 7994835896d254f0bacf09306d86c2b8 467 SUPERFAMILY SSF53092 40 195 2.88E-22 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UA74_05900 7994835896d254f0bacf09306d86c2b8 467 Pfam PF00557 Metallopeptidase family M24 204 441 4.8E-43 T 12-10-2018 IPR000994 Peptidase M24 UA74_05900 7994835896d254f0bacf09306d86c2b8 467 Gene3D G3DSA:3.40.350.10 35 166 3.4E-14 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UA74_27220 69c5de80d6df02338de906a5331f88c0 631 SUPERFAMILY SSF53738 276 360 8.24E-19 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 150 159 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 SUPERFAMILY SSF55957 488 571 5.76E-9 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 55 190 1.8E-40 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 275 360 4.7E-21 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 SUPERFAMILY SSF53738 353 496 1.81E-24 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 SUPERFAMILY SSF53738 45 197 3.06E-42 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 Gene3D G3DSA:3.40.120.10 45 196 4.5E-46 T 12-10-2018 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 149 163 5.9E-6 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 345 360 5.9E-6 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 374 491 1.3E-16 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 Gene3D G3DSA:3.40.120.10 373 496 2.2E-25 T 12-10-2018 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 534 571 7.4E-7 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UA74_27220 69c5de80d6df02338de906a5331f88c0 631 Gene3D G3DSA:3.40.120.10 270 372 1.4E-19 T 12-10-2018 UA74_17485 515559e31661273d21a7edb4d29e9f90 257 SMART SM00342 23 106 3.5E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_17485 515559e31661273d21a7edb4d29e9f90 257 SUPERFAMILY SSF46689 59 107 1.3E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_17485 515559e31661273d21a7edb4d29e9f90 257 SUPERFAMILY SSF46689 9 56 1.97E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_17485 515559e31661273d21a7edb4d29e9f90 257 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 60 102 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UA74_17485 515559e31661273d21a7edb4d29e9f90 257 Gene3D G3DSA:1.10.10.60 5 59 7.7E-13 T 12-10-2018 UA74_17485 515559e31661273d21a7edb4d29e9f90 257 Pfam PF12833 Helix-turn-helix domain 29 107 2.9E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_17485 515559e31661273d21a7edb4d29e9f90 257 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 75 90 9.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_17485 515559e31661273d21a7edb4d29e9f90 257 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 90 106 9.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_17485 515559e31661273d21a7edb4d29e9f90 257 Gene3D G3DSA:1.10.10.60 60 111 6.8E-16 T 12-10-2018 UA74_09950 bb95bdee6f0e03cf4b73a0f2321d5767 268 Gene3D G3DSA:3.20.20.70 26 268 1.2E-87 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_09950 bb95bdee6f0e03cf4b73a0f2321d5767 268 Pfam PF00977 Histidine biosynthesis protein 30 259 1.2E-59 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 UA74_09950 bb95bdee6f0e03cf4b73a0f2321d5767 268 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 27 268 1.4E-121 T 12-10-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 UA74_09950 bb95bdee6f0e03cf4b73a0f2321d5767 268 SUPERFAMILY SSF51366 28 265 8.63E-58 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UA74_09950 bb95bdee6f0e03cf4b73a0f2321d5767 268 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 29 266 31.733 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 Pfam PF01341 Glycosyl hydrolases family 6 72 416 9.4E-88 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 Gene3D G3DSA:3.20.20.40 50 467 4.7E-167 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PRINTS PR00733 Glycosyl hydrolase family 6 signature 225 238 5.2E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PRINTS PR00733 Glycosyl hydrolase family 6 signature 329 342 5.2E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PRINTS PR00733 Glycosyl hydrolase family 6 signature 70 89 5.2E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PRINTS PR00733 Glycosyl hydrolase family 6 signature 121 134 5.2E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PRINTS PR00733 Glycosyl hydrolase family 6 signature 153 168 5.2E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PRINTS PR00733 Glycosyl hydrolase family 6 signature 265 275 5.2E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PRINTS PR00733 Glycosyl hydrolase family 6 signature 370 390 5.2E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PRINTS PR00733 Glycosyl hydrolase family 6 signature 393 407 5.2E-37 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 SMART SM00637 492 592 6.0E-42 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 SUPERFAMILY SSF49384 490 592 2.09E-32 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PIRSF PIRSF001100 486 593 1.0 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 PIRSF PIRSF001100 4 467 6.1E-104 T 12-10-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 Pfam PF00553 Cellulose binding domain 492 592 3.6E-30 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 Gene3D G3DSA:2.60.40.290 488 593 2.9E-34 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 SUPERFAMILY SSF51989 50 467 9.29E-96 T 12-10-2018 IPR036434 1, 4-beta cellobiohydrolase superfamily GO:0004553|GO:0030245 UA74_06610 e0a5e907e87f8caacceb85df40144290 593 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 557 570 - T 12-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 UA74_02210 13e0cbd2c572e0f02da878ecf9a0b7da 495 Gene3D G3DSA:1.20.1720.10 22 256 6.2E-56 T 12-10-2018 UA74_02210 13e0cbd2c572e0f02da878ecf9a0b7da 495 Pfam PF07690 Major Facilitator Superfamily 27 417 2.4E-53 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_02210 13e0cbd2c572e0f02da878ecf9a0b7da 495 Gene3D G3DSA:1.20.1250.20 268 471 1.9E-16 T 12-10-2018 UA74_02210 13e0cbd2c572e0f02da878ecf9a0b7da 495 SUPERFAMILY SSF103473 15 467 6.1E-68 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_02210 13e0cbd2c572e0f02da878ecf9a0b7da 495 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 420 2.8E-69 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 Pfam PF13414 TPR repeat 491 532 8.8E-10 T 12-10-2018 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 Gene3D G3DSA:1.25.40.10 269 513 1.9E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 Gene3D G3DSA:1.25.40.10 514 701 2.8E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SUPERFAMILY SSF48452 457 681 8.72E-40 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SUPERFAMILY SSF48452 324 515 1.93E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 Pfam PF13432 Tetratricopeptide repeat 591 649 9.8E-6 T 12-10-2018 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 484 517 3.6E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 450 483 0.035 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 552 585 3.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 620 653 16.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 586 619 0.54 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 654 686 92.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_19300 33b6b37ba5ef1f9e7ec5ea788e30cc08 705 SMART SM00028 518 551 0.011 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_09760 29a2184a694a49993d2d4a845fbf15cb 601 Pfam PF03703 Bacterial PH domain 90 171 4.8E-11 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_05660 987fa0c2e3fa9e761b6899a73d8f3be0 192 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 77 177 4.8E-7 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal UA74_05660 987fa0c2e3fa9e761b6899a73d8f3be0 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 6.1E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05660 987fa0c2e3fa9e761b6899a73d8f3be0 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 6.1E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05660 987fa0c2e3fa9e761b6899a73d8f3be0 192 SUPERFAMILY SSF46689 4 70 1.49E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_05660 987fa0c2e3fa9e761b6899a73d8f3be0 192 SUPERFAMILY SSF48498 76 174 4.08E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_05660 987fa0c2e3fa9e761b6899a73d8f3be0 192 Gene3D G3DSA:1.10.357.10 2 184 7.8E-27 T 12-10-2018 UA74_05660 987fa0c2e3fa9e761b6899a73d8f3be0 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 2.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 3.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 3.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.0E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 9.9E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 9.9E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.9E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 Gene3D G3DSA:3.40.50.720 3 240 1.3E-71 T 12-10-2018 UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 SUPERFAMILY SSF51735 7 233 4.48E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_13640 f4abf4a992a9e51e45efaf31e9907253 241 Pfam PF00106 short chain dehydrogenase 8 203 2.1E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_01100 8915c1e13db87f76e2a9bbdc6bfa6d24 150 Gene3D G3DSA:3.30.1490.190 97 150 1.6E-11 T 12-10-2018 UA74_01100 8915c1e13db87f76e2a9bbdc6bfa6d24 150 Gene3D G3DSA:1.10.10.10 16 94 4.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_01100 8915c1e13db87f76e2a9bbdc6bfa6d24 150 Pfam PF01475 Ferric uptake regulator family 25 114 1.1E-18 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 UA74_01100 8915c1e13db87f76e2a9bbdc6bfa6d24 150 SUPERFAMILY SSF46785 18 145 1.21E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20550 a1739a90756d77730fab6b1f39d60953 547 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_20550 a1739a90756d77730fab6b1f39d60953 547 SMART SM00220 13 277 3.5E-53 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_20550 a1739a90756d77730fab6b1f39d60953 547 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_20550 a1739a90756d77730fab6b1f39d60953 547 Gene3D G3DSA:1.10.510.10 95 275 5.0E-48 T 12-10-2018 UA74_20550 a1739a90756d77730fab6b1f39d60953 547 Gene3D G3DSA:3.30.200.20 4 92 2.2E-25 T 12-10-2018 UA74_20550 a1739a90756d77730fab6b1f39d60953 547 SUPERFAMILY SSF48452 411 531 3.79E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_20550 a1739a90756d77730fab6b1f39d60953 547 Gene3D G3DSA:1.25.40.10 397 534 2.6E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_20550 a1739a90756d77730fab6b1f39d60953 547 SUPERFAMILY SSF56112 17 310 6.92E-71 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_20550 a1739a90756d77730fab6b1f39d60953 547 Pfam PF00069 Protein kinase domain 17 264 9.0E-45 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_07100 7d46095d551946dd117dad4972eaab04 305 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 42 300 3.3E-68 T 12-10-2018 IPR014337 Ectoine/Hydroxyectoine ABC transporter, substrate-binding protein EhuB GO:0033294|GO:0051470 UA74_07100 7d46095d551946dd117dad4972eaab04 305 Gene3D G3DSA:3.40.190.10 140 246 7.2E-58 T 12-10-2018 UA74_07100 7d46095d551946dd117dad4972eaab04 305 SUPERFAMILY SSF53850 55 282 1.9E-35 T 12-10-2018 UA74_07100 7d46095d551946dd117dad4972eaab04 305 SMART SM00062 54 288 1.4E-27 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_07100 7d46095d551946dd117dad4972eaab04 305 Gene3D G3DSA:3.40.190.10 61 282 7.2E-58 T 12-10-2018 UA74_07100 7d46095d551946dd117dad4972eaab04 305 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 55 280 1.6E-33 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_16800 008d227f3fc6d28752277daf940b6b0f 267 Gene3D G3DSA:3.40.50.150 11 241 2.5E-34 T 12-10-2018 UA74_16800 008d227f3fc6d28752277daf940b6b0f 267 SUPERFAMILY SSF53335 17 202 1.12E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_16800 008d227f3fc6d28752277daf940b6b0f 267 Pfam PF13649 Methyltransferase domain 35 131 2.7E-17 T 12-10-2018 UA74_29295 351267061e6db3c7a45d514694b6e515 182 Pfam PF04542 Sigma-70 region 2 18 79 6.9E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_29295 351267061e6db3c7a45d514694b6e515 182 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 168 1.2E-44 T 12-10-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 UA74_29295 351267061e6db3c7a45d514694b6e515 182 SUPERFAMILY SSF88659 109 166 5.61E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_29295 351267061e6db3c7a45d514694b6e515 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 164 6.9E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_29295 351267061e6db3c7a45d514694b6e515 182 Gene3D G3DSA:1.10.10.10 83 169 3.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_29295 351267061e6db3c7a45d514694b6e515 182 Pfam PF08281 Sigma-70, region 4 111 161 1.8E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_29295 351267061e6db3c7a45d514694b6e515 182 SUPERFAMILY SSF88946 3 97 6.28E-15 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_29295 351267061e6db3c7a45d514694b6e515 182 Gene3D G3DSA:1.10.1740.10 1 82 1.6E-9 T 12-10-2018 UA74_00155 0254a6c93c61d37aedf2f1813fa72717 152 SMART SM00240 79 129 2.7E-13 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_00155 0254a6c93c61d37aedf2f1813fa72717 152 Pfam PF00498 FHA domain 80 143 1.0E-14 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_00155 0254a6c93c61d37aedf2f1813fa72717 152 SUPERFAMILY SSF49879 51 151 2.49E-24 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 UA74_00155 0254a6c93c61d37aedf2f1813fa72717 152 Gene3D G3DSA:2.60.200.20 37 152 2.8E-26 T 12-10-2018 UA74_07790 cc7784811b843844e3e8a9192f61a410 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 4.6E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_07790 cc7784811b843844e3e8a9192f61a410 222 SUPERFAMILY SSF52172 1 178 1.04E-34 T 12-10-2018 IPR011006 CheY-like superfamily UA74_07790 cc7784811b843844e3e8a9192f61a410 222 Pfam PF00072 Response regulator receiver domain 3 112 1.3E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_07790 cc7784811b843844e3e8a9192f61a410 222 Gene3D G3DSA:3.40.50.2300 1 123 1.6E-29 T 12-10-2018 UA74_07790 cc7784811b843844e3e8a9192f61a410 222 Gene3D G3DSA:1.10.10.10 124 220 5.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_07790 cc7784811b843844e3e8a9192f61a410 222 SMART SM00862 145 217 4.0E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_07790 cc7784811b843844e3e8a9192f61a410 222 SMART SM00448 1 112 7.0E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_28620 4250a771bddd0030e3b7befc50309f73 174 SUPERFAMILY SSF46785 4 166 4.68E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_28620 4250a771bddd0030e3b7befc50309f73 174 Gene3D G3DSA:1.10.10.10 1 88 1.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28620 4250a771bddd0030e3b7befc50309f73 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 1.2E-15 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_20280 14f2cb3ae389a6639888b29877c8073e 432 SUPERFAMILY SSF55874 203 328 1.06E-12 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_20280 14f2cb3ae389a6639888b29877c8073e 432 SMART SM00387 216 330 0.0068 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_20280 14f2cb3ae389a6639888b29877c8073e 432 Gene3D G3DSA:3.30.565.10 182 329 2.7E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_10465 1cef450b5a943092e6018ba982e61315 130 Pfam PF13411 MerR HTH family regulatory protein 1 69 6.1E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_10465 1cef450b5a943092e6018ba982e61315 130 SMART SM00422 1 70 2.2E-33 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_10465 1cef450b5a943092e6018ba982e61315 130 Gene3D G3DSA:1.10.1660.10 1 129 4.3E-30 T 12-10-2018 UA74_10465 1cef450b5a943092e6018ba982e61315 130 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_10465 1cef450b5a943092e6018ba982e61315 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_10465 1cef450b5a943092e6018ba982e61315 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_10465 1cef450b5a943092e6018ba982e61315 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 6.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_10465 1cef450b5a943092e6018ba982e61315 130 SUPERFAMILY SSF46955 1 113 1.68E-27 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_30310 76992c5de1b4d18f6ccdabbb4e7a61c3 102 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 15 83 24.494 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UA74_30310 76992c5de1b4d18f6ccdabbb4e7a61c3 102 SMART SM01234 15 82 3.8E-43 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UA74_30310 76992c5de1b4d18f6ccdabbb4e7a61c3 102 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 30 82 2.0E-19 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UA74_30310 76992c5de1b4d18f6ccdabbb4e7a61c3 102 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 21 91 1.3E-27 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UA74_30310 76992c5de1b4d18f6ccdabbb4e7a61c3 102 Pfam PF01809 Haemolytic domain 17 82 3.4E-28 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UA74_13605 abb770a3ede5b9f55e8782bd674964b8 260 Gene3D G3DSA:3.40.50.1580 15 256 1.9E-54 T 12-10-2018 UA74_13605 abb770a3ede5b9f55e8782bd674964b8 260 Pfam PF01048 Phosphorylase superfamily 29 249 9.0E-34 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_13605 abb770a3ede5b9f55e8782bd674964b8 260 SUPERFAMILY SSF53167 16 253 7.07E-52 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 UA74_06410 443f868adad3d32a01ffaba185825ee8 138 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 88 3.8E-12 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_06410 443f868adad3d32a01ffaba185825ee8 138 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 10 136 3.4E-31 T 12-10-2018 IPR019920 F420-binding domain, putative UA74_06410 443f868adad3d32a01ffaba185825ee8 138 SUPERFAMILY SSF50475 1 136 6.55E-24 T 12-10-2018 UA74_06410 443f868adad3d32a01ffaba185825ee8 138 Gene3D G3DSA:2.30.110.10 5 136 2.5E-28 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_06440 c69137e759379b71c5cc6099a4dab63d 319 PIRSF PIRSF000089 1 319 2.9E-95 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 UA74_06440 c69137e759379b71c5cc6099a4dab63d 319 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 195 277 1.6E-34 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 UA74_06440 c69137e759379b71c5cc6099a4dab63d 319 SUPERFAMILY SSF52467 194 313 3.53E-46 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UA74_06440 c69137e759379b71c5cc6099a4dab63d 319 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 258 284 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 UA74_06440 c69137e759379b71c5cc6099a4dab63d 319 Pfam PF01012 Electron transfer flavoprotein domain 4 172 3.7E-26 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UA74_06440 c69137e759379b71c5cc6099a4dab63d 319 SMART SM00893 4 182 7.7E-24 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UA74_06440 c69137e759379b71c5cc6099a4dab63d 319 Gene3D G3DSA:3.40.50.620 1 181 2.4E-34 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_06440 c69137e759379b71c5cc6099a4dab63d 319 SUPERFAMILY SSF52402 4 177 2.01E-37 T 12-10-2018 UA74_06440 c69137e759379b71c5cc6099a4dab63d 319 Gene3D G3DSA:3.40.50.1220 188 319 1.2E-54 T 12-10-2018 UA74_09795 4794a33d448ad3895076851ca90d38b5 533 Pfam PF00202 Aminotransferase class-III 131 528 2.0E-109 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_09795 4794a33d448ad3895076851ca90d38b5 533 Gene3D G3DSA:3.40.640.10 169 439 1.8E-153 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_09795 4794a33d448ad3895076851ca90d38b5 533 Gene3D G3DSA:3.90.1150.10 113 522 1.8E-153 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_09795 4794a33d448ad3895076851ca90d38b5 533 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 351 388 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_09795 4794a33d448ad3895076851ca90d38b5 533 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 105 533 47.557 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 UA74_09795 4794a33d448ad3895076851ca90d38b5 533 SUPERFAMILY SSF53383 109 530 4.83E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_09795 4794a33d448ad3895076851ca90d38b5 533 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 117 529 2.2E-162 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 UA74_19310 069b95d6aefd14bf2c71255b1fc9ab3d 307 Pfam PF03704 Bacterial transcriptional activator domain 124 269 7.8E-34 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_19310 069b95d6aefd14bf2c71255b1fc9ab3d 307 SMART SM01043 124 269 3.3E-30 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_19310 069b95d6aefd14bf2c71255b1fc9ab3d 307 Pfam PF00486 Transcriptional regulatory protein, C terminal 38 93 1.4E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_19310 069b95d6aefd14bf2c71255b1fc9ab3d 307 Gene3D G3DSA:1.10.10.10 9 119 5.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19310 069b95d6aefd14bf2c71255b1fc9ab3d 307 SUPERFAMILY SSF48452 121 282 1.02E-29 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19310 069b95d6aefd14bf2c71255b1fc9ab3d 307 SMART SM00862 31 117 1.3E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_19310 069b95d6aefd14bf2c71255b1fc9ab3d 307 Gene3D G3DSA:1.25.40.10 121 301 2.8E-36 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_19310 069b95d6aefd14bf2c71255b1fc9ab3d 307 SUPERFAMILY SSF46894 18 95 1.28E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_29755 9615838b00f8abad5789da8958f30eb3 277 Gene3D G3DSA:3.40.50.720 9 273 1.0E-58 T 12-10-2018 UA74_29755 9615838b00f8abad5789da8958f30eb3 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 173 201 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_29755 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 205 2.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29755 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 123 2.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29755 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 2.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29755 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 224 2.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29755 9615838b00f8abad5789da8958f30eb3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 237 257 2.6E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29755 9615838b00f8abad5789da8958f30eb3 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 273 6.0E-40 T 12-10-2018 UA74_29755 9615838b00f8abad5789da8958f30eb3 277 SUPERFAMILY SSF51735 20 274 4.75E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17640 b27802ca66cd497363c6dda668eb7001 363 SUPERFAMILY SSF53659 4 344 2.69E-28 T 12-10-2018 UA74_17640 b27802ca66cd497363c6dda668eb7001 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 106 339 2.9E-13 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_17640 b27802ca66cd497363c6dda668eb7001 363 SMART SM01329 4 340 3.0E-7 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_17640 b27802ca66cd497363c6dda668eb7001 363 Gene3D G3DSA:3.40.718.10 3 352 4.4E-34 T 12-10-2018 UA74_10365 0c87b9acfbaf000b67286b681546633b 598 SUPERFAMILY SSF90123 24 334 1.06E-69 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_10365 0c87b9acfbaf000b67286b681546633b 598 Gene3D G3DSA:3.40.50.300 347 598 4.3E-79 T 12-10-2018 UA74_10365 0c87b9acfbaf000b67286b681546633b 598 Pfam PF00664 ABC transporter transmembrane region 39 309 2.4E-41 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_10365 0c87b9acfbaf000b67286b681546633b 598 Gene3D G3DSA:1.20.1560.10 16 337 3.6E-79 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_10365 0c87b9acfbaf000b67286b681546633b 598 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_10365 0c87b9acfbaf000b67286b681546633b 598 Pfam PF00005 ABC transporter 372 519 2.5E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_10365 0c87b9acfbaf000b67286b681546633b 598 SUPERFAMILY SSF52540 350 591 9.26E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10365 0c87b9acfbaf000b67286b681546633b 598 SMART SM00382 381 573 5.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_14200 1e87366ba2da511ecaa96720417a1346 444 SUPERFAMILY SSF103473 52 435 1.7E-39 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_14200 1e87366ba2da511ecaa96720417a1346 444 Gene3D G3DSA:1.20.1250.20 51 241 1.4E-12 T 12-10-2018 UA74_14200 1e87366ba2da511ecaa96720417a1346 444 Gene3D G3DSA:1.20.1250.20 256 443 1.2E-15 T 12-10-2018 UA74_14200 1e87366ba2da511ecaa96720417a1346 444 Pfam PF07690 Major Facilitator Superfamily 61 379 8.3E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_12430 82d2c3fe287d3b8ebfbf1860d6bd529e 297 SUPERFAMILY SSF52266 54 243 2.96E-28 T 12-10-2018 UA74_12430 82d2c3fe287d3b8ebfbf1860d6bd529e 297 Gene3D G3DSA:3.40.50.1110 55 245 2.3E-22 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_12430 82d2c3fe287d3b8ebfbf1860d6bd529e 297 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 58 234 4.9E-19 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain UA74_26925 a8556c1a593c8ac626b6fb5c048ae2c0 209 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 197 6.8E-44 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 UA74_26925 a8556c1a593c8ac626b6fb5c048ae2c0 209 Gene3D G3DSA:3.90.950.10 1 205 2.7E-52 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like UA74_26925 a8556c1a593c8ac626b6fb5c048ae2c0 209 Hamap MF_00528 Septum formation protein Maf [maf]. 2 204 24.665 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 UA74_26925 a8556c1a593c8ac626b6fb5c048ae2c0 209 Pfam PF02545 Maf-like protein 2 199 1.5E-43 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 UA74_26925 a8556c1a593c8ac626b6fb5c048ae2c0 209 PIRSF PIRSF006305 1 206 4.0E-38 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 UA74_26925 a8556c1a593c8ac626b6fb5c048ae2c0 209 SUPERFAMILY SSF52972 2 198 4.71E-44 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like UA74_14465 d72d44cbe16b68c2c66964220d85c652 200 SUPERFAMILY SSF46689 15 84 3.04E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14465 d72d44cbe16b68c2c66964220d85c652 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 2.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14465 d72d44cbe16b68c2c66964220d85c652 200 SUPERFAMILY SSF48498 107 193 1.07E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_14465 d72d44cbe16b68c2c66964220d85c652 200 Gene3D G3DSA:1.10.357.10 11 196 2.2E-39 T 12-10-2018 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 Gene3D G3DSA:3.30.70.260 458 531 8.9E-19 T 12-10-2018 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 Gene3D G3DSA:3.40.50.720 10 308 1.8E-120 T 12-10-2018 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 Gene3D G3DSA:3.30.1330.90 319 457 7.5E-42 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 SUPERFAMILY SSF52283 6 137 2.46E-36 T 12-10-2018 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 SUPERFAMILY SSF55021 456 526 4.25E-13 T 12-10-2018 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 Pfam PF01842 ACT domain 459 517 3.3E-9 T 12-10-2018 IPR002912 ACT domain UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 284 1.2E-59 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 Gene3D G3DSA:3.40.50.720 101 282 1.8E-120 T 12-10-2018 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 SUPERFAMILY SSF143548 325 453 8.11E-31 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 316 9.0E-34 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 SUPERFAMILY SSF51735 103 285 7.41E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_25920 389b0ff344ff9f2992bd18154f4739c9 532 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 9 527 8.8E-185 T 12-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 SMART SM01230 104 383 6.9E-150 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 4.2E-134 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 390 402 - T 12-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 Gene3D G3DSA:3.30.590.10 107 462 8.2E-149 T 12-10-2018 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 Gene3D G3DSA:3.10.20.70 4 106 1.3E-37 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 SUPERFAMILY SSF55931 105 473 4.41E-137 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 SUPERFAMILY SSF54368 5 103 1.83E-31 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 5.7E-25 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 473 2.0E-202 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UA74_25110 d3b3f0f22cfa45083e4ef86c62f51a2c 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UA74_01680 2edc8580439b80e91269e38fee4cf4fc 161 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 7 157 2.3E-45 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_01680 2edc8580439b80e91269e38fee4cf4fc 161 Pfam PF02542 YgbB family 7 156 3.3E-46 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_01680 2edc8580439b80e91269e38fee4cf4fc 161 Gene3D G3DSA:3.30.1330.50 2 160 4.1E-57 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_01680 2edc8580439b80e91269e38fee4cf4fc 161 SUPERFAMILY SSF69765 6 158 1.31E-49 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_01680 2edc8580439b80e91269e38fee4cf4fc 161 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 40 55 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_01680 2edc8580439b80e91269e38fee4cf4fc 161 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 6 158 30.374 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UA74_09990 3d26986ce7240b1bb58a3accda3480d8 296 Pfam PF13560 Helix-turn-helix domain 12 72 2.9E-11 T 12-10-2018 UA74_09990 3d26986ce7240b1bb58a3accda3480d8 296 SUPERFAMILY SSF47413 12 67 3.38E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_09990 3d26986ce7240b1bb58a3accda3480d8 296 Gene3D G3DSA:1.10.260.40 8 70 1.2E-10 T 12-10-2018 UA74_09990 3d26986ce7240b1bb58a3accda3480d8 296 SMART SM00530 16 71 5.8E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_04135 9c2a2e4265fc4e538e6c1acfc53d4b28 360 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 26 337 6.2E-114 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 UA74_04135 9c2a2e4265fc4e538e6c1acfc53d4b28 360 Gene3D G3DSA:3.30.540.10 30 333 9.4E-133 T 12-10-2018 UA74_04135 9c2a2e4265fc4e538e6c1acfc53d4b28 360 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 26 333 1.1E-143 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 UA74_04135 9c2a2e4265fc4e538e6c1acfc53d4b28 360 PIRSF PIRSF004532 24 344 1.0E-148 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 UA74_04135 9c2a2e4265fc4e538e6c1acfc53d4b28 360 SUPERFAMILY SSF56655 24 336 8.16E-115 T 12-10-2018 UA74_04135 9c2a2e4265fc4e538e6c1acfc53d4b28 360 Gene3D G3DSA:3.40.190.90 146 307 9.4E-133 T 12-10-2018 UA74_23810 f30aa92c55faff9ea2dad2fcd8100485 461 Pfam PF00544 Pectate lyase 167 378 1.4E-50 T 12-10-2018 IPR002022 Pectate lyase UA74_23810 f30aa92c55faff9ea2dad2fcd8100485 461 SMART SM00656 152 384 3.1E-46 T 12-10-2018 IPR002022 Pectate lyase UA74_23810 f30aa92c55faff9ea2dad2fcd8100485 461 SUPERFAMILY SSF51126 59 460 1.32E-75 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor UA74_23810 f30aa92c55faff9ea2dad2fcd8100485 461 Gene3D G3DSA:2.160.20.10 58 461 4.8E-148 T 12-10-2018 IPR012334 Pectin lyase fold UA74_20580 942887ec30f4d57556711bb95c4b9cd5 1357 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 605 619 2.7E-5 T 12-10-2018 UA74_20580 942887ec30f4d57556711bb95c4b9cd5 1357 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 557 573 2.7E-5 T 12-10-2018 UA74_20580 942887ec30f4d57556711bb95c4b9cd5 1357 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 872 884 2.7E-5 T 12-10-2018 UA74_20580 942887ec30f4d57556711bb95c4b9cd5 1357 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 875 881 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_20580 942887ec30f4d57556711bb95c4b9cd5 1357 Gene3D G3DSA:3.40.50.150 809 963 2.9E-5 T 12-10-2018 UA74_20580 942887ec30f4d57556711bb95c4b9cd5 1357 Gene3D G3DSA:3.40.50.150 545 750 5.6E-20 T 12-10-2018 UA74_20580 942887ec30f4d57556711bb95c4b9cd5 1357 SUPERFAMILY SSF53335 283 954 4.67E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_14155 11d708c38be1226de630349ea692a693 224 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 41 201 4.7E-38 T 12-10-2018 IPR023635 Peptide deformylase UA74_14155 11d708c38be1226de630349ea692a693 224 Gene3D G3DSA:3.90.45.10 37 223 2.3E-53 T 12-10-2018 IPR036821 Peptide deformylase superfamily UA74_14155 11d708c38be1226de630349ea692a693 224 SUPERFAMILY SSF56420 36 201 1.57E-53 T 12-10-2018 IPR036821 Peptide deformylase superfamily UA74_14155 11d708c38be1226de630349ea692a693 224 Pfam PF01327 Polypeptide deformylase 39 194 1.2E-45 T 12-10-2018 IPR023635 Peptide deformylase UA74_14155 11d708c38be1226de630349ea692a693 224 PRINTS PR01576 Peptide deformylase signature 131 142 3.9E-35 T 12-10-2018 IPR023635 Peptide deformylase UA74_14155 11d708c38be1226de630349ea692a693 224 PRINTS PR01576 Peptide deformylase signature 143 161 3.9E-35 T 12-10-2018 IPR023635 Peptide deformylase UA74_14155 11d708c38be1226de630349ea692a693 224 PRINTS PR01576 Peptide deformylase signature 69 98 3.9E-35 T 12-10-2018 IPR023635 Peptide deformylase UA74_14155 11d708c38be1226de630349ea692a693 224 PRINTS PR01576 Peptide deformylase signature 162 191 3.9E-35 T 12-10-2018 IPR023635 Peptide deformylase UA74_14155 11d708c38be1226de630349ea692a693 224 Hamap MF_00163 Peptide deformylase [def]. 37 204 28.334 T 12-10-2018 IPR023635 Peptide deformylase UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 Gene3D G3DSA:3.40.710.10 345 551 8.1E-57 T 12-10-2018 UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 340 540 1.1E-40 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 Gene3D G3DSA:3.40.710.10 168 238 5.6E-8 T 12-10-2018 UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 444 458 1.0E-21 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 206 225 1.0E-21 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 429 443 1.0E-21 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 372 394 1.0E-21 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 336 556 2.6E-49 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 182 335 1.7E-23 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UA74_01510 988b72a63ec3e4d3d7fbb4b552d93d0d 563 SUPERFAMILY SSF56601 184 561 3.98E-57 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_18565 fc1f37935f4532a0a6891b4c3d66d101 267 Gene3D G3DSA:1.20.120.450 2 150 3.0E-13 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_18565 fc1f37935f4532a0a6891b4c3d66d101 267 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 6 257 9.8E-94 T 12-10-2018 IPR017518 Conserved hypothetical protein CHP03084 UA74_18565 fc1f37935f4532a0a6891b4c3d66d101 267 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 224 4.9E-36 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_18565 fc1f37935f4532a0a6891b4c3d66d101 267 SUPERFAMILY SSF109854 3 153 1.7E-22 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_18565 fc1f37935f4532a0a6891b4c3d66d101 267 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 147 1.0E-21 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_07185 c7d5a38784f419aa473a6cb77212e7eb 156 Gene3D G3DSA:3.10.180.10 5 145 2.2E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_07185 c7d5a38784f419aa473a6cb77212e7eb 156 SUPERFAMILY SSF54593 9 147 2.75E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_07185 c7d5a38784f419aa473a6cb77212e7eb 156 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 123 1.8E-17 T 12-10-2018 UA74_07185 c7d5a38784f419aa473a6cb77212e7eb 156 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 12 143 1.7E-35 T 12-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 UA74_18235 7e9795af5227a4ed40f9ae7ec1bfea85 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 325 2.2E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_30005 97ea5211417dc33e509d221e7f8af149 98 SUPERFAMILY SSF54995 1 94 3.4E-31 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30005 97ea5211417dc33e509d221e7f8af149 98 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 20.783 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 UA74_30005 97ea5211417dc33e509d221e7f8af149 98 Gene3D G3DSA:3.30.70.60 1 98 1.2E-30 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 UA74_30005 97ea5211417dc33e509d221e7f8af149 98 Pfam PF01250 Ribosomal protein S6 3 92 1.9E-26 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30005 97ea5211417dc33e509d221e7f8af149 98 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 8.4E-25 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_14455 06b51b7218703d7fca4152357cf822cf 523 Pfam PF07690 Major Facilitator Superfamily 22 414 1.1E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_14455 06b51b7218703d7fca4152357cf822cf 523 Gene3D G3DSA:1.20.1720.10 17 227 3.2E-38 T 12-10-2018 UA74_14455 06b51b7218703d7fca4152357cf822cf 523 SUPERFAMILY SSF103473 8 483 5.75E-53 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_24190 e653fb76a4d9bcbbdd24c05c70d5a394 338 SUPERFAMILY SSF51735 111 299 6.21E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_24190 e653fb76a4d9bcbbdd24c05c70d5a394 338 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 209 231 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_24190 e653fb76a4d9bcbbdd24c05c70d5a394 338 Gene3D G3DSA:3.40.50.720 18 318 4.8E-81 T 12-10-2018 UA74_24190 e653fb76a4d9bcbbdd24c05c70d5a394 338 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 133 298 8.3E-44 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_24190 e653fb76a4d9bcbbdd24c05c70d5a394 338 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 238 254 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_24190 e653fb76a4d9bcbbdd24c05c70d5a394 338 Gene3D G3DSA:3.40.50.720 110 297 4.8E-81 T 12-10-2018 UA74_24190 e653fb76a4d9bcbbdd24c05c70d5a394 338 SUPERFAMILY SSF52283 27 146 1.05E-10 T 12-10-2018 UA74_24135 7ff845bfe2562f95d56e8e9562f7f695 325 Pfam PF00106 short chain dehydrogenase 51 247 1.1E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24135 7ff845bfe2562f95d56e8e9562f7f695 325 Gene3D G3DSA:3.40.50.720 41 324 5.3E-66 T 12-10-2018 UA74_24135 7ff845bfe2562f95d56e8e9562f7f695 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 229 7.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24135 7ff845bfe2562f95d56e8e9562f7f695 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 137 7.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24135 7ff845bfe2562f95d56e8e9562f7f695 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 231 248 7.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24135 7ff845bfe2562f95d56e8e9562f7f695 325 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 50 67 7.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24135 7ff845bfe2562f95d56e8e9562f7f695 325 SUPERFAMILY SSF51735 46 308 3.1E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 59 69 1.0E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 94 110 1.0E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 43 55 1.0E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 254 270 1.0E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 77 86 1.0E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 574 589 1.0E-17 T 12-10-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 Gene3D G3DSA:3.40.50.1820 309 437 1.8E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 Gene3D G3DSA:3.40.50.1820 57 292 8.6E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 Gene3D G3DSA:2.60.120.260 454 609 5.9E-39 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 SUPERFAMILY SSF53474 43 425 2.26E-76 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 402 603 3.9E-39 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 73 375 2.3E-66 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 SUPERFAMILY SSF49785 467 611 1.23E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_08710 8c699797863d10221a09697cf9f3d1ee 621 SMART SM00939 390 606 5.0E-40 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 SUPERFAMILY SSF52172 2 133 2.28E-33 T 12-10-2018 IPR011006 CheY-like superfamily UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 Gene3D G3DSA:3.40.50.12740 2 214 2.9E-67 T 12-10-2018 UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 SMART SM00421 151 208 4.5E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 SMART SM00448 2 117 1.6E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 6.2E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 Pfam PF00072 Response regulator receiver domain 4 118 1.4E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_22390 10ceabdcf396ab534225af1ca5b491e8 216 SUPERFAMILY SSF46894 145 215 2.24E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 Gene3D G3DSA:3.40.50.300 256 388 3.9E-8 T 12-10-2018 UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 Gene3D G3DSA:1.25.40.10 91 255 2.1E-43 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 SUPERFAMILY SSF46894 3 88 6.8E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 SUPERFAMILY SSF52540 258 500 1.04E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 SMART SM00862 16 88 2.5E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 76 1.6E-7 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 SMART SM01043 93 238 4.5E-42 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 SUPERFAMILY SSF48452 91 255 4.83E-38 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 Gene3D G3DSA:1.10.10.10 1 89 2.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_03315 39e166e084e30fe2f0126e1f4c837522 895 Pfam PF03704 Bacterial transcriptional activator domain 93 238 1.0E-34 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_17500 e73e5c0b7237b98ad16fba92fce1a644 181 Gene3D G3DSA:3.30.530.20 7 170 4.2E-46 T 12-10-2018 IPR023393 START-like domain superfamily UA74_17500 e73e5c0b7237b98ad16fba92fce1a644 181 SUPERFAMILY SSF55961 13 162 3.14E-43 T 12-10-2018 UA74_17500 e73e5c0b7237b98ad16fba92fce1a644 181 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 27 161 5.0E-28 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_07470 34ca5a29df3e3ad2e6eeacf7e774def3 293 Pfam PF00106 short chain dehydrogenase 6 202 2.9E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07470 34ca5a29df3e3ad2e6eeacf7e774def3 293 SUPERFAMILY SSF51735 5 249 5.31E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_07470 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07470 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07470 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 4.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07470 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07470 34ca5a29df3e3ad2e6eeacf7e774def3 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 4.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_07470 34ca5a29df3e3ad2e6eeacf7e774def3 293 Gene3D G3DSA:3.40.50.720 1 289 5.8E-53 T 12-10-2018 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 602 614 - T 12-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 Pfam PF00343 Carbohydrate phosphorylase 128 173 2.5E-4 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 Pfam PF00343 Carbohydrate phosphorylase 279 624 6.6E-16 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 Gene3D G3DSA:3.40.50.2000 110 191 4.9E-9 T 12-10-2018 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 111 712 6.0E-229 T 12-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 SUPERFAMILY SSF53756 5 746 3.04E-194 T 12-10-2018 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 Gene3D G3DSA:3.40.50.2000 460 640 1.6E-35 T 12-10-2018 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 Pfam PF11897 Protein of unknown function (DUF3417) 13 123 8.9E-33 T 12-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 PIRSF PIRSF000460 1 800 3.3E-251 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 UA74_06275 13111c18a7a021a36b0ff7e376510578 852 Gene3D G3DSA:3.40.50.2000 271 430 1.5E-14 T 12-10-2018 UA74_16550 59f61edfb0891fe5b6b18d7fe7c5fa04 338 SUPERFAMILY SSF53901 12 335 4.99E-60 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16550 59f61edfb0891fe5b6b18d7fe7c5fa04 338 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 248 335 3.5E-26 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_16550 59f61edfb0891fe5b6b18d7fe7c5fa04 338 Gene3D G3DSA:3.40.47.10 10 337 9.2E-112 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_16550 59f61edfb0891fe5b6b18d7fe7c5fa04 338 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 192 3.2E-22 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_16550 59f61edfb0891fe5b6b18d7fe7c5fa04 338 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 12 335 1.9E-88 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_19895 138fcd77abc1f1e67c2a8c6ade422719 363 SMART SM00382 73 228 9.7E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_19895 138fcd77abc1f1e67c2a8c6ade422719 363 Pfam PF07728 AAA domain (dynein-related subfamily) 77 218 4.6E-33 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 UA74_19895 138fcd77abc1f1e67c2a8c6ade422719 363 SUPERFAMILY SSF52540 53 296 3.19E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19895 138fcd77abc1f1e67c2a8c6ade422719 363 Gene3D G3DSA:3.40.50.300 57 236 3.2E-23 T 12-10-2018 UA74_22910 0afe9ca8a85fc8214cf3276d1838ed43 457 Pfam PF01547 Bacterial extracellular solute-binding protein 63 349 1.4E-50 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_22910 0afe9ca8a85fc8214cf3276d1838ed43 457 Gene3D G3DSA:3.40.190.10 61 416 1.5E-136 T 12-10-2018 UA74_22910 0afe9ca8a85fc8214cf3276d1838ed43 457 SUPERFAMILY SSF53850 28 452 2.42E-78 T 12-10-2018 UA74_22910 0afe9ca8a85fc8214cf3276d1838ed43 457 Gene3D G3DSA:3.40.190.10 160 445 1.5E-136 T 12-10-2018 UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 Gene3D G3DSA:3.40.50.720 3 259 1.6E-79 T 12-10-2018 UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 SUPERFAMILY SSF51735 13 257 1.05E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 256 1.9E-59 T 12-10-2018 UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 186 0.002 T 12-10-2018 UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.9E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.9E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.9E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.9E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.9E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_15065 2f067411e847cd28fc7d35bdda8fdf8a 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_06915 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 Gene3D G3DSA:2.60.120.10 1 115 1.2E-39 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_06915 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 35.544 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 UA74_06915 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 2.0E-38 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 UA74_06915 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 Pfam PF06339 Ectoine synthase 2 125 4.1E-54 T 12-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 UA74_06915 f0ce8d5c39d489fe05f32b9b2c5e6f5d 141 SUPERFAMILY SSF51182 18 125 1.83E-19 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_18015 0e7ca215e75c3e1a9f7e8cfad1302ac0 276 Gene3D G3DSA:3.40.50.720 2 276 1.9E-72 T 12-10-2018 UA74_18015 0e7ca215e75c3e1a9f7e8cfad1302ac0 276 Pfam PF13460 NAD(P)H-binding 7 175 1.6E-26 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_18015 0e7ca215e75c3e1a9f7e8cfad1302ac0 276 SUPERFAMILY SSF51735 2 267 3.12E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14735 439b9848d1d62cadbfe2a856b54f46a6 243 Gene3D G3DSA:3.10.180.10 111 227 3.6E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_14735 439b9848d1d62cadbfe2a856b54f46a6 243 SUPERFAMILY SSF54593 117 228 5.48E-11 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_22755 b351d7c5b017eefe0c3cb8876ae7fbe0 152 SUPERFAMILY SSF46785 5 141 3.06E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22755 b351d7c5b017eefe0c3cb8876ae7fbe0 152 Gene3D G3DSA:1.10.10.10 2 144 4.4E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22755 b351d7c5b017eefe0c3cb8876ae7fbe0 152 Pfam PF12802 MarR family 31 85 4.1E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_22755 b351d7c5b017eefe0c3cb8876ae7fbe0 152 SMART SM00347 26 126 3.1E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_12055 62d2633a70b726d021395ce8874982f7 409 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 46 398 1.7E-35 T 12-10-2018 IPR003770 Endolytic murein transglycosylase UA74_12055 62d2633a70b726d021395ce8874982f7 409 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 42 406 24.82 T 12-10-2018 IPR003770 Endolytic murein transglycosylase UA74_12055 62d2633a70b726d021395ce8874982f7 409 Gene3D G3DSA:1.10.8.1150 77 147 1.3E-7 T 12-10-2018 UA74_12055 62d2633a70b726d021395ce8874982f7 409 Pfam PF02618 YceG-like family 82 399 3.9E-54 T 12-10-2018 IPR003770 Endolytic murein transglycosylase UA74_21145 1eab5d7f588c12003da7f041d8400704 415 SMART SM00833 250 366 5.5E-36 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_21145 1eab5d7f588c12003da7f041d8400704 415 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 251 366 1.1E-17 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UA74_21145 1eab5d7f588c12003da7f041d8400704 415 Gene3D G3DSA:3.40.50.300 21 220 1.1E-11 T 12-10-2018 UA74_21145 1eab5d7f588c12003da7f041d8400704 415 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 58 179 2.1E-8 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain UA74_21145 1eab5d7f588c12003da7f041d8400704 415 SUPERFAMILY SSF90002 251 366 2.88E-10 T 12-10-2018 UA74_16030 490aac82e6d373177b53c0d791fb33be 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16030 490aac82e6d373177b53c0d791fb33be 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16030 490aac82e6d373177b53c0d791fb33be 227 Pfam PF00106 short chain dehydrogenase 9 176 1.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16030 490aac82e6d373177b53c0d791fb33be 227 Gene3D G3DSA:3.40.50.720 7 195 3.4E-21 T 12-10-2018 UA74_16030 490aac82e6d373177b53c0d791fb33be 227 SUPERFAMILY SSF51735 8 184 5.27E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_20995 d4199f9e5fe0ae378d5fdabe0ca967d1 228 Gene3D G3DSA:1.10.357.10 38 227 2.5E-25 T 12-10-2018 UA74_20995 d4199f9e5fe0ae378d5fdabe0ca967d1 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 57 94 3.5E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_20995 d4199f9e5fe0ae378d5fdabe0ca967d1 228 SUPERFAMILY SSF46689 46 114 1.1E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 Gene3D G3DSA:1.10.287.130 284 397 4.4E-32 T 12-10-2018 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 Pfam PF00512 His Kinase A (phospho-acceptor) domain 334 395 6.6E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 438 545 5.0E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 SUPERFAMILY SSF55874 385 548 1.57E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 Pfam PF00672 HAMP domain 281 329 9.4E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 SUPERFAMILY SSF47384 316 396 4.51E-20 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 SUPERFAMILY SSF158472 282 329 1.57E-7 T 12-10-2018 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 Gene3D G3DSA:3.30.565.10 424 557 1.5E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 SMART SM00387 437 547 5.7E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 502 2.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 544 2.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 488 2.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 525 2.1E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 SMART SM00304 280 332 3.1E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_21825 4339f24067c6a1cecccc4d482d9bfd83 563 SMART SM00388 333 396 1.6E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_18995 807dafa7d19252663d8d08afd28b5fac 367 SMART SM00421 291 348 3.6E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18995 807dafa7d19252663d8d08afd28b5fac 367 SUPERFAMILY SSF46894 284 348 2.93E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_18995 807dafa7d19252663d8d08afd28b5fac 367 ProSitePatterns PS00622 LuxR-type HTH domain signature. 308 335 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18995 807dafa7d19252663d8d08afd28b5fac 367 Pfam PF00196 Bacterial regulatory proteins, luxR family 294 347 3.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18995 807dafa7d19252663d8d08afd28b5fac 367 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 324 336 1.8E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18995 807dafa7d19252663d8d08afd28b5fac 367 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 308 324 1.8E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18995 807dafa7d19252663d8d08afd28b5fac 367 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 294 308 1.8E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_18995 807dafa7d19252663d8d08afd28b5fac 367 Gene3D G3DSA:1.10.10.10 228 353 3.7E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27565 d0005ab91978837d0be1041f8be03873 267 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 3 247 4.4E-32 T 12-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase UA74_25385 df89d959af7626137641082735069c01 292 Pfam PF13560 Helix-turn-helix domain 13 72 4.6E-11 T 12-10-2018 UA74_25385 df89d959af7626137641082735069c01 292 Gene3D G3DSA:1.10.260.40 2 74 1.6E-7 T 12-10-2018 UA74_25385 df89d959af7626137641082735069c01 292 SMART SM00530 17 72 7.9E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_25385 df89d959af7626137641082735069c01 292 SUPERFAMILY SSF47413 10 74 6.52E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_09840 003b6fd8436d11bcfc9d28b9fbe1e7ab 306 Gene3D G3DSA:3.90.1170.20 39 303 8.0E-98 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 UA74_09840 003b6fd8436d11bcfc9d28b9fbe1e7ab 306 SUPERFAMILY SSF54675 30 136 5.42E-27 T 12-10-2018 UA74_09840 003b6fd8436d11bcfc9d28b9fbe1e7ab 306 Gene3D G3DSA:3.20.20.70 141 296 8.0E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_09840 003b6fd8436d11bcfc9d28b9fbe1e7ab 306 SUPERFAMILY SSF51690 137 305 5.89E-52 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 UA74_09840 003b6fd8436d11bcfc9d28b9fbe1e7ab 306 PIRSF PIRSF006250 28 306 4.4E-90 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 UA74_09840 003b6fd8436d11bcfc9d28b9fbe1e7ab 306 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 137 304 5.4E-53 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 UA74_09840 003b6fd8436d11bcfc9d28b9fbe1e7ab 306 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 35 304 3.8E-85 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 UA74_09840 003b6fd8436d11bcfc9d28b9fbe1e7ab 306 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 47 135 1.1E-21 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 1.8E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 1.8E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 1.8E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 ProSitePatterns PS00552 MerR-type HTH domain signature. 14 36 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 Gene3D G3DSA:1.10.1660.10 5 134 9.0E-32 T 12-10-2018 UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 Pfam PF09278 MerR, DNA binding 53 118 1.1E-16 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 Pfam PF00376 MerR family regulatory protein 12 48 7.2E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 SUPERFAMILY SSF46955 11 131 5.13E-26 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 SMART SM00422 11 79 3.7E-25 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13905 d570a06f9463d0dbc7baab95894a3d7b 183 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 10 149 8.6E-68 T 12-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 UA74_11275 d8afdab05b2d656d8df96f936ad0992f 351 SMART SM00382 47 239 2.6E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_11275 d8afdab05b2d656d8df96f936ad0992f 351 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_11275 d8afdab05b2d656d8df96f936ad0992f 351 Gene3D G3DSA:3.40.50.300 23 269 1.2E-61 T 12-10-2018 UA74_11275 d8afdab05b2d656d8df96f936ad0992f 351 SUPERFAMILY SSF52540 19 245 5.24E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11275 d8afdab05b2d656d8df96f936ad0992f 351 Pfam PF00005 ABC transporter 43 184 7.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_08440 0fbd0ba72565bbfd6f7a8cba447b8599 253 Gene3D G3DSA:3.30.420.40 112 250 2.1E-35 T 12-10-2018 UA74_08440 0fbd0ba72565bbfd6f7a8cba447b8599 253 Pfam PF00480 ROK family 9 168 2.2E-14 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_08440 0fbd0ba72565bbfd6f7a8cba447b8599 253 SUPERFAMILY SSF53067 8 248 1.19E-32 T 12-10-2018 UA74_08440 0fbd0ba72565bbfd6f7a8cba447b8599 253 Gene3D G3DSA:3.30.420.40 4 111 1.2E-20 T 12-10-2018 UA74_05740 7c34744e2b419af19430721917e8efa0 413 Gene3D G3DSA:3.50.50.60 2 382 9.4E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_05740 7c34744e2b419af19430721917e8efa0 413 Pfam PF01494 FAD binding domain 5 321 1.0E-19 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_05740 7c34744e2b419af19430721917e8efa0 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.4E-7 T 12-10-2018 UA74_05740 7c34744e2b419af19430721917e8efa0 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.4E-7 T 12-10-2018 UA74_05740 7c34744e2b419af19430721917e8efa0 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 1.4E-7 T 12-10-2018 UA74_05740 7c34744e2b419af19430721917e8efa0 413 SUPERFAMILY SSF51905 5 375 2.18E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_00925 ee56a3bb4cfea5af3792104fbcecfc94 521 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 432 7.5E-56 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_00925 ee56a3bb4cfea5af3792104fbcecfc94 521 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 6 25 3.4E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal UA74_00925 ee56a3bb4cfea5af3792104fbcecfc94 521 SUPERFAMILY SSF53850 35 517 4.34E-89 T 12-10-2018 UA74_00925 ee56a3bb4cfea5af3792104fbcecfc94 521 Gene3D G3DSA:3.90.76.10 50 189 3.5E-79 T 12-10-2018 UA74_00925 ee56a3bb4cfea5af3792104fbcecfc94 521 PIRSF PIRSF002741 1 518 4.6E-56 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_00925 ee56a3bb4cfea5af3792104fbcecfc94 521 Gene3D G3DSA:3.40.190.10 190 502 3.5E-79 T 12-10-2018 UA74_00925 ee56a3bb4cfea5af3792104fbcecfc94 521 Gene3D G3DSA:3.10.105.10 265 494 3.5E-79 T 12-10-2018 UA74_24215 37b365e2da702ffb5096c24189f235cc 443 Gene3D G3DSA:3.40.190.10 158 424 6.2E-111 T 12-10-2018 UA74_24215 37b365e2da702ffb5096c24189f235cc 443 SUPERFAMILY SSF53850 51 429 1.71E-67 T 12-10-2018 UA74_24215 37b365e2da702ffb5096c24189f235cc 443 Gene3D G3DSA:3.40.190.10 66 363 6.2E-111 T 12-10-2018 UA74_24215 37b365e2da702ffb5096c24189f235cc 443 Pfam PF13416 Bacterial extracellular solute-binding protein 64 364 9.2E-32 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_24215 37b365e2da702ffb5096c24189f235cc 443 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 154 171 - T 12-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 UA74_11380 30ac66c7b581934718fc432c27bdfcb9 130 SUPERFAMILY SSF51230 4 127 1.96E-42 T 12-10-2018 IPR011053 Single hybrid motif UA74_11380 30ac66c7b581934718fc432c27bdfcb9 130 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 38.033 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 UA74_11380 30ac66c7b581934718fc432c27bdfcb9 130 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_11380 30ac66c7b581934718fc432c27bdfcb9 130 Pfam PF01597 Glycine cleavage H-protein 8 126 3.2E-43 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate UA74_11380 30ac66c7b581934718fc432c27bdfcb9 130 Gene3D G3DSA:2.40.50.100 2 129 5.9E-51 T 12-10-2018 UA74_11380 30ac66c7b581934718fc432c27bdfcb9 130 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 127 1.7E-48 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 UA74_12355 33f78f1ea7083b87809350988550e969 411 Gene3D G3DSA:3.40.50.1260 187 401 2.4E-139 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 Pfam PF00162 Phosphoglycerate kinase 22 401 7.7E-143 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 16 411 40.509 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 Gene3D G3DSA:3.40.50.1260 22 409 2.4E-139 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 SUPERFAMILY SSF53748 20 411 1.65E-139 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 26 36 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 185 207 2.5E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 120 135 2.5E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 208 227 2.5E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 21 37 2.5E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 387 404 2.5E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 330 355 2.5E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 42 64 2.5E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 155 177 2.5E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PRINTS PR00477 Phosphoglycerate kinase family signature 363 374 2.5E-76 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12355 33f78f1ea7083b87809350988550e969 411 PIRSF PIRSF000724 8 411 2.1E-132 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12945 6a35fc9a4af8faaf3aa485ab267917ce 404 Gene3D G3DSA:3.40.630.30 1 134 9.6E-30 T 12-10-2018 UA74_12945 6a35fc9a4af8faaf3aa485ab267917ce 404 Pfam PF13527 Acetyltransferase (GNAT) domain 6 131 1.5E-22 T 12-10-2018 UA74_12945 6a35fc9a4af8faaf3aa485ab267917ce 404 Gene3D G3DSA:3.30.1050.10 298 394 2.8E-19 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily UA74_12945 6a35fc9a4af8faaf3aa485ab267917ce 404 SUPERFAMILY SSF55718 300 404 1.37E-16 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily UA74_12945 6a35fc9a4af8faaf3aa485ab267917ce 404 SUPERFAMILY SSF55729 5 299 1.02E-49 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_12945 6a35fc9a4af8faaf3aa485ab267917ce 404 Hamap MF_01812 N-acetyltransferase Eis [eis]. 3 404 31.546 T 12-10-2018 IPR022902 N-acetyltransferase Eis UA74_12945 6a35fc9a4af8faaf3aa485ab267917ce 404 Gene3D G3DSA:3.40.630.30 135 292 6.9E-37 T 12-10-2018 UA74_12945 6a35fc9a4af8faaf3aa485ab267917ce 404 Pfam PF13530 Sterol carrier protein domain 180 400 8.2E-46 T 12-10-2018 IPR025559 Enhanced intracellular survival protein domain UA74_13820 eeba76c708bf04b2588bfbbf6032f9d4 175 SUPERFAMILY SSF50876 40 158 1.15E-31 T 12-10-2018 IPR036896 Avidin-like superfamily UA74_13820 eeba76c708bf04b2588bfbbf6032f9d4 175 Pfam PF01382 Avidin family 40 152 8.3E-24 T 12-10-2018 IPR005468 Avidin/streptavidin UA74_13820 eeba76c708bf04b2588bfbbf6032f9d4 175 PRINTS PR00709 Avidin signature 88 100 8.7E-24 T 12-10-2018 IPR005469 Avidin UA74_13820 eeba76c708bf04b2588bfbbf6032f9d4 175 PRINTS PR00709 Avidin signature 60 68 8.7E-24 T 12-10-2018 IPR005469 Avidin UA74_13820 eeba76c708bf04b2588bfbbf6032f9d4 175 PRINTS PR00709 Avidin signature 110 120 8.7E-24 T 12-10-2018 IPR005469 Avidin UA74_13820 eeba76c708bf04b2588bfbbf6032f9d4 175 PRINTS PR00709 Avidin signature 40 54 8.7E-24 T 12-10-2018 IPR005469 Avidin UA74_13820 eeba76c708bf04b2588bfbbf6032f9d4 175 PRINTS PR00709 Avidin signature 142 158 8.7E-24 T 12-10-2018 IPR005469 Avidin UA74_13820 eeba76c708bf04b2588bfbbf6032f9d4 175 PRINTS PR00709 Avidin signature 126 137 8.7E-24 T 12-10-2018 IPR005469 Avidin UA74_13820 eeba76c708bf04b2588bfbbf6032f9d4 175 Gene3D G3DSA:2.40.128.30 34 165 8.2E-48 T 12-10-2018 IPR036896 Avidin-like superfamily UA74_09730 1fdcbf7237aa262581f70c3b52753edd 281 TIGRFAM TIGR00077 lspA: signal peptidase II 81 233 4.7E-26 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_09730 1fdcbf7237aa262581f70c3b52753edd 281 ProSitePatterns PS00855 Signal peptidases II signature. 172 184 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_09730 1fdcbf7237aa262581f70c3b52753edd 281 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 80 237 15.094 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_09730 1fdcbf7237aa262581f70c3b52753edd 281 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 212 228 3.2E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_09730 1fdcbf7237aa262581f70c3b52753edd 281 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 169 184 3.2E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_09730 1fdcbf7237aa262581f70c3b52753edd 281 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 127 135 3.2E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_09730 1fdcbf7237aa262581f70c3b52753edd 281 Pfam PF01252 Signal peptidase (SPase) II 89 230 2.6E-28 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_21475 05e7a98af73fd475b8e65c6c3a3a329e 285 Gene3D G3DSA:3.40.50.720 4 261 1.4E-77 T 12-10-2018 UA74_21475 05e7a98af73fd475b8e65c6c3a3a329e 285 Pfam PF13460 NAD(P)H-binding 6 177 3.5E-24 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_21475 05e7a98af73fd475b8e65c6c3a3a329e 285 Gene3D G3DSA:3.90.25.10 134 262 1.4E-77 T 12-10-2018 UA74_21475 05e7a98af73fd475b8e65c6c3a3a329e 285 SUPERFAMILY SSF51735 2 232 2.24E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_21405 bf1608e1eb26199da3ffe6f5c0b8bc70 697 SUPERFAMILY SSF52540 243 688 2.86E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21405 bf1608e1eb26199da3ffe6f5c0b8bc70 697 Gene3D G3DSA:3.40.50.300 245 365 1.1E-8 T 12-10-2018 UA74_21405 bf1608e1eb26199da3ffe6f5c0b8bc70 697 Gene3D G3DSA:3.40.50.300 584 692 6.7E-12 T 12-10-2018 UA74_21405 bf1608e1eb26199da3ffe6f5c0b8bc70 697 Pfam PF13245 AAA domain 259 497 7.8E-14 T 12-10-2018 UA74_21405 bf1608e1eb26199da3ffe6f5c0b8bc70 697 Gene3D G3DSA:3.40.50.300 411 535 9.4E-13 T 12-10-2018 UA74_03735 84181b45b4724377f2b4e0b26d8d79ae 181 Pfam PF04977 Septum formation initiator 69 143 1.6E-12 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC UA74_27425 095dad3aaf3d522cf6725241604ea3b8 111 SUPERFAMILY SSF46785 12 95 4.77E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_27425 095dad3aaf3d522cf6725241604ea3b8 111 Pfam PF13601 Winged helix DNA-binding domain 17 94 5.5E-15 T 12-10-2018 IPR027395 Winged helix DNA-binding domain UA74_27425 095dad3aaf3d522cf6725241604ea3b8 111 Gene3D G3DSA:1.10.10.10 6 96 1.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10370 d0c99e2b5e50daaf693701f2a6a32fcb 285 SUPERFAMILY SSF53474 12 282 1.11E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_10370 d0c99e2b5e50daaf693701f2a6a32fcb 285 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 96 110 2.7E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_10370 d0c99e2b5e50daaf693701f2a6a32fcb 285 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 30 38 2.7E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_10370 d0c99e2b5e50daaf693701f2a6a32fcb 285 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 56 67 2.7E-9 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UA74_10370 d0c99e2b5e50daaf693701f2a6a32fcb 285 Gene3D G3DSA:3.40.50.1820 15 284 7.4E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_10370 d0c99e2b5e50daaf693701f2a6a32fcb 285 Pfam PF00561 alpha/beta hydrolase fold 28 264 6.9E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_13105 aea3ba06251ad293f26ead475378da42 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 1.8E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13105 aea3ba06251ad293f26ead475378da42 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 1.8E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13105 aea3ba06251ad293f26ead475378da42 235 SUPERFAMILY SSF48498 96 199 5.93E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_13105 aea3ba06251ad293f26ead475378da42 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 9.9E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13105 aea3ba06251ad293f26ead475378da42 235 Gene3D G3DSA:1.10.357.10 15 205 2.5E-50 T 12-10-2018 UA74_13105 aea3ba06251ad293f26ead475378da42 235 SUPERFAMILY SSF46689 18 97 1.75E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_26110 55f9bed45318e541a1e6c1c92b42d629 335 SMART SM00559 49 177 1.0E-31 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 UA74_26110 55f9bed45318e541a1e6c1c92b42d629 335 Gene3D G3DSA:2.40.290.10 1 177 5.9E-14 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily UA74_26110 55f9bed45318e541a1e6c1c92b42d629 335 Pfam PF02735 Ku70/Ku80 beta-barrel domain 8 185 1.2E-34 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 UA74_26110 55f9bed45318e541a1e6c1c92b42d629 335 SUPERFAMILY SSF100939 1 253 6.08E-51 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily UA74_26110 55f9bed45318e541a1e6c1c92b42d629 335 PIRSF PIRSF006493 280 334 240.0 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UA74_26110 55f9bed45318e541a1e6c1c92b42d629 335 PIRSF PIRSF006493 1 294 3.4E-89 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UA74_26110 55f9bed45318e541a1e6c1c92b42d629 335 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 252 1.0E-86 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UA74_26110 55f9bed45318e541a1e6c1c92b42d629 335 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 250 32.198 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UA74_22500 bc1be17595bb27fb51d4f9ae2cb6d2fe 337 Gene3D G3DSA:3.40.50.300 38 333 6.2E-80 T 12-10-2018 UA74_22500 bc1be17595bb27fb51d4f9ae2cb6d2fe 337 SMART SM00382 60 248 7.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_22500 bc1be17595bb27fb51d4f9ae2cb6d2fe 337 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22500 bc1be17595bb27fb51d4f9ae2cb6d2fe 337 Pfam PF00005 ABC transporter 51 199 1.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_22500 bc1be17595bb27fb51d4f9ae2cb6d2fe 337 SUPERFAMILY SSF52540 45 271 4.5E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07525 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 SUPERFAMILY SSF51430 3 319 1.7E-81 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_07525 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 Gene3D G3DSA:3.20.20.100 2 333 3.7E-97 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_07525 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 Pfam PF00248 Aldo/keto reductase family 16 318 2.9E-62 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_07525 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 PRINTS PR00069 Aldo-keto reductase signature 122 140 1.8E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_07525 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 PRINTS PR00069 Aldo-keto reductase signature 252 276 1.8E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_07525 e3d85a35479b25cd6ba56cc6f3a6d1ec 337 PRINTS PR00069 Aldo-keto reductase signature 153 170 1.8E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_17740 75f77f6a41888fb74b3a8687d19d3455 172 Pfam PF04542 Sigma-70 region 2 15 79 6.3E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_17740 75f77f6a41888fb74b3a8687d19d3455 172 Gene3D G3DSA:1.10.10.10 95 170 8.7E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17740 75f77f6a41888fb74b3a8687d19d3455 172 SUPERFAMILY SSF88659 104 167 2.06E-6 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_17740 75f77f6a41888fb74b3a8687d19d3455 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 168 9.9E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_17740 75f77f6a41888fb74b3a8687d19d3455 172 SUPERFAMILY SSF88946 4 90 4.71E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_17740 75f77f6a41888fb74b3a8687d19d3455 172 Gene3D G3DSA:1.10.1740.10 3 80 1.6E-6 T 12-10-2018 UA74_18810 c253b043dbb0c50b7e7ea462effdfd38 297 Gene3D G3DSA:1.10.10.10 1 89 1.8E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18810 c253b043dbb0c50b7e7ea462effdfd38 297 Pfam PF03466 LysR substrate binding domain 89 295 1.9E-28 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_18810 c253b043dbb0c50b7e7ea462effdfd38 297 Gene3D G3DSA:3.40.190.10 92 283 8.0E-30 T 12-10-2018 UA74_18810 c253b043dbb0c50b7e7ea462effdfd38 297 SUPERFAMILY SSF46785 1 111 1.49E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18810 c253b043dbb0c50b7e7ea462effdfd38 297 Gene3D G3DSA:3.40.190.10 170 270 8.0E-30 T 12-10-2018 UA74_18810 c253b043dbb0c50b7e7ea462effdfd38 297 SUPERFAMILY SSF53850 89 296 4.89E-26 T 12-10-2018 UA74_18810 c253b043dbb0c50b7e7ea462effdfd38 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.2E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 Gene3D G3DSA:3.40.50.720 1 255 6.6E-63 T 12-10-2018 UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 Pfam PF00106 short chain dehydrogenase 3 187 7.7E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.5E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.5E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.5E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.5E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.5E-26 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PIRSF PIRSF000126 1 257 1.9E-70 T 12-10-2018 UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 182 6.2E-4 T 12-10-2018 UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 SUPERFAMILY SSF51735 3 250 3.23E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 4.5E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 4.5E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_29610 3cf52d4557aeaa8a9d0bee08d3b72ac9 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 4.5E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_03355 3fc2968e2d7bb63b493a5ef66ed7c966 127 Pfam PF01042 Endoribonuclease L-PSP 15 125 4.8E-18 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UA74_03355 3fc2968e2d7bb63b493a5ef66ed7c966 127 Gene3D G3DSA:3.30.1330.40 4 127 1.5E-29 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_03355 3fc2968e2d7bb63b493a5ef66ed7c966 127 SUPERFAMILY SSF55298 9 127 5.97E-28 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_12395 e026233bb402d6d125112db86c856103 256 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 247 6.5E-70 T 12-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 UA74_12395 e026233bb402d6d125112db86c856103 256 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 13 240 8.0E-75 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 UA74_12395 e026233bb402d6d125112db86c856103 256 Gene3D G3DSA:3.40.50.1360 2 249 1.0E-86 T 12-10-2018 UA74_12395 e026233bb402d6d125112db86c856103 256 SUPERFAMILY SSF100950 6 249 3.24E-65 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 427 453 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 258 271 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 Gene3D G3DSA:1.10.601.10 163 200 4.0E-9 T 12-10-2018 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 Gene3D G3DSA:1.10.601.10 201 306 3.4E-52 T 12-10-2018 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 Pfam PF04545 Sigma-70, region 4 402 455 1.4E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 Gene3D G3DSA:1.10.10.10 390 467 3.0E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 230 455 1.9E-35 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 Gene3D G3DSA:1.10.10.10 307 382 2.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 63 467 33.064 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 Pfam PF04542 Sigma-70 region 2 234 303 1.7E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 SUPERFAMILY SSF88659 307 380 1.8E-22 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 282 290 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 258 271 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 442 453 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 406 418 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 PRINTS PR00046 Major sigma-70 factor signature 427 442 2.7E-29 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 SUPERFAMILY SSF88946 162 304 8.5E-54 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 230 466 2.0E-113 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 SUPERFAMILY SSF88659 366 466 2.88E-26 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 Pfam PF04539 Sigma-70 region 3 313 388 1.6E-28 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UA74_08435 94f0e009e16551f6b1b756bea0d4a859 467 Pfam PF00140 Sigma-70 factor, region 1.2 165 196 8.8E-16 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_18340 d22e8994c5c14bb602165561086b4d32 264 Gene3D G3DSA:2.60.120.200 23 258 1.8E-22 T 12-10-2018 UA74_18340 d22e8994c5c14bb602165561086b4d32 264 Pfam PF00722 Glycosyl hydrolases family 16 69 238 9.4E-7 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 UA74_18340 d22e8994c5c14bb602165561086b4d32 264 SUPERFAMILY SSF49899 24 243 6.86E-19 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UA74_02290 eb450d4a686a7db7563fbd3482c32798 188 Pfam PF08281 Sigma-70, region 4 133 179 3.5E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_02290 eb450d4a686a7db7563fbd3482c32798 188 SUPERFAMILY SSF88659 110 184 3.36E-11 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_02290 eb450d4a686a7db7563fbd3482c32798 188 Pfam PF04542 Sigma-70 region 2 26 93 5.0E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_02290 eb450d4a686a7db7563fbd3482c32798 188 SUPERFAMILY SSF88946 4 103 2.35E-27 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_02290 eb450d4a686a7db7563fbd3482c32798 188 Gene3D G3DSA:1.10.10.10 127 186 1.5E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02290 eb450d4a686a7db7563fbd3482c32798 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 180 7.3E-23 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_02290 eb450d4a686a7db7563fbd3482c32798 188 Gene3D G3DSA:1.10.1740.10 2 90 1.1E-24 T 12-10-2018 UA74_17775 4319c5a44c4236cacd2de9653b480b5f 188 Gene3D G3DSA:3.40.630.30 5 171 1.8E-27 T 12-10-2018 UA74_17775 4319c5a44c4236cacd2de9653b480b5f 188 SUPERFAMILY SSF55729 3 167 6.6E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_17775 4319c5a44c4236cacd2de9653b480b5f 188 Pfam PF13302 Acetyltransferase (GNAT) domain 12 146 1.9E-13 T 12-10-2018 IPR000182 GNAT domain UA74_03955 458bebc456bff504bf7abdfb5a5fd205 461 SMART SM00220 15 264 4.7E-42 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_03955 458bebc456bff504bf7abdfb5a5fd205 461 Pfam PF00069 Protein kinase domain 16 260 1.5E-38 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_03955 458bebc456bff504bf7abdfb5a5fd205 461 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_03955 458bebc456bff504bf7abdfb5a5fd205 461 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_03955 458bebc456bff504bf7abdfb5a5fd205 461 Gene3D G3DSA:1.10.510.10 95 277 2.1E-46 T 12-10-2018 UA74_03955 458bebc456bff504bf7abdfb5a5fd205 461 PIRSF PIRSF000654 27 274 3.8E-24 T 12-10-2018 UA74_03955 458bebc456bff504bf7abdfb5a5fd205 461 SUPERFAMILY SSF56112 12 263 2.6E-63 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_03955 458bebc456bff504bf7abdfb5a5fd205 461 Gene3D G3DSA:3.30.200.20 6 93 7.4E-18 T 12-10-2018 UA74_09640 17c8b41020f7a026b7939d4156a0753b 434 Pfam PF01098 Cell cycle protein 2 352 5.6E-112 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_09640 17c8b41020f7a026b7939d4156a0753b 434 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 2 351 4.0E-113 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_09640 17c8b41020f7a026b7939d4156a0753b 434 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 310 334 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_15485 c410ff044403d95649392d6a4c4d0837 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.6E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15485 c410ff044403d95649392d6a4c4d0837 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.6E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15485 c410ff044403d95649392d6a4c4d0837 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.6E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15485 c410ff044403d95649392d6a4c4d0837 119 SUPERFAMILY SSF46955 1 113 1.61E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_15485 c410ff044403d95649392d6a4c4d0837 119 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.9E-19 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15485 c410ff044403d95649392d6a4c4d0837 119 SMART SM00422 1 69 6.8E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15485 c410ff044403d95649392d6a4c4d0837 119 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15485 c410ff044403d95649392d6a4c4d0837 119 Gene3D G3DSA:1.10.1660.10 1 118 8.7E-31 T 12-10-2018 UA74_10350 c561d27ed1b5a943cb2852f8a08ee45c 219 Pfam PF13671 AAA domain 42 152 3.0E-9 T 12-10-2018 UA74_10350 c561d27ed1b5a943cb2852f8a08ee45c 219 Gene3D G3DSA:3.40.50.300 35 211 8.3E-28 T 12-10-2018 UA74_10350 c561d27ed1b5a943cb2852f8a08ee45c 219 SUPERFAMILY SSF52540 41 206 2.71E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00125 0696fd1caf19574db8a08c63589dde85 180 Pfam PF12680 SnoaL-like domain 60 159 2.2E-10 T 12-10-2018 IPR037401 SnoaL-like domain UA74_00125 0696fd1caf19574db8a08c63589dde85 180 Gene3D G3DSA:3.10.450.50 50 176 8.6E-24 T 12-10-2018 UA74_00125 0696fd1caf19574db8a08c63589dde85 180 SUPERFAMILY SSF54427 52 169 7.62E-20 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_17235 02b3a0c816ff6cfd9113952830273de2 346 Gene3D G3DSA:1.10.630.10 3 256 3.6E-33 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17235 02b3a0c816ff6cfd9113952830273de2 346 PRINTS PR00359 B-class P450 signature 212 223 6.9E-5 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17235 02b3a0c816ff6cfd9113952830273de2 346 PRINTS PR00359 B-class P450 signature 76 92 6.9E-5 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17235 02b3a0c816ff6cfd9113952830273de2 346 PRINTS PR00359 B-class P450 signature 230 257 6.9E-5 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17235 02b3a0c816ff6cfd9113952830273de2 346 SUPERFAMILY SSF48264 36 253 1.09E-29 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_22315 b5add19b2b1c07fd6c245ca5334d8edd 394 Pfam PF02515 CoA-transferase family III 1 362 9.4E-118 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 UA74_22315 b5add19b2b1c07fd6c245ca5334d8edd 394 Gene3D G3DSA:3.40.50.10540 1 381 5.3E-120 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily UA74_22315 b5add19b2b1c07fd6c245ca5334d8edd 394 Gene3D G3DSA:3.30.1540.10 222 314 5.3E-120 T 12-10-2018 UA74_22315 b5add19b2b1c07fd6c245ca5334d8edd 394 SUPERFAMILY SSF89796 1 387 1.96E-125 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily UA74_24495 bba91bf14f70b5f267ad0c636980635a 339 SUPERFAMILY SSF52540 106 274 1.98E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24495 bba91bf14f70b5f267ad0c636980635a 339 Gene3D G3DSA:3.40.50.300 104 310 1.4E-75 T 12-10-2018 UA74_24495 bba91bf14f70b5f267ad0c636980635a 339 Pfam PF02562 PhoH-like protein 107 310 8.2E-94 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 UA74_21650 cb570c8b0d920e0a0ff1ca043f83a3cf 180 Gene3D G3DSA:3.10.450.50 13 164 1.2E-38 T 12-10-2018 UA74_21650 cb570c8b0d920e0a0ff1ca043f83a3cf 180 SUPERFAMILY SSF54427 17 148 1.72E-34 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_21650 cb570c8b0d920e0a0ff1ca043f83a3cf 180 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 20 143 1.6E-23 T 12-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 UA74_21650 cb570c8b0d920e0a0ff1ca043f83a3cf 180 Pfam PF14534 Domain of unknown function (DUF4440) 24 135 1.5E-12 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 UA74_10410 8b7f266505938d0a9cb34a595dda5a20 551 Pfam PF00535 Glycosyl transferase family 2 5 101 1.4E-12 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_10410 8b7f266505938d0a9cb34a595dda5a20 551 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 380 518 2.0E-26 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 UA74_10410 8b7f266505938d0a9cb34a595dda5a20 551 SUPERFAMILY SSF53448 2 200 5.7E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_10410 8b7f266505938d0a9cb34a595dda5a20 551 SUPERFAMILY SSF56784 376 531 1.16E-40 T 12-10-2018 IPR036412 HAD-like superfamily UA74_10410 8b7f266505938d0a9cb34a595dda5a20 551 Pfam PF13242 HAD-hyrolase-like 471 539 6.8E-14 T 12-10-2018 UA74_10410 8b7f266505938d0a9cb34a595dda5a20 551 Gene3D G3DSA:3.90.550.10 2 196 2.5E-27 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_10410 8b7f266505938d0a9cb34a595dda5a20 551 Gene3D G3DSA:3.40.50.1000 364 546 5.1E-45 T 12-10-2018 IPR023214 HAD superfamily UA74_10410 8b7f266505938d0a9cb34a595dda5a20 551 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 379 516 4.5E-30 T 12-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 UA74_22430 e8651ed907859fede8c5dd8fc8879010 247 Gene3D G3DSA:2.20.25.570 140 204 2.0E-39 T 12-10-2018 UA74_22430 e8651ed907859fede8c5dd8fc8879010 247 SUPERFAMILY SSF53335 8 232 5.72E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_22430 e8651ed907859fede8c5dd8fc8879010 247 Pfam PF13649 Methyltransferase domain 40 132 4.0E-16 T 12-10-2018 UA74_22430 e8651ed907859fede8c5dd8fc8879010 247 Gene3D G3DSA:3.40.50.150 38 236 2.0E-39 T 12-10-2018 UA74_08820 1b80d205831754c01949639248c39275 285 Pfam PF02517 CAAX protease self-immunity 182 270 3.2E-15 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 UA74_26365 1cd0437f37071c3474f010e834bd6cb7 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 212 6.4E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_26365 1cd0437f37071c3474f010e834bd6cb7 223 Gene3D G3DSA:1.10.3720.10 13 212 4.1E-24 T 12-10-2018 IPR035906 MetI-like superfamily UA74_26365 1cd0437f37071c3474f010e834bd6cb7 223 SUPERFAMILY SSF161098 18 203 7.59E-27 T 12-10-2018 IPR035906 MetI-like superfamily UA74_10305 3a0a036a43201c2706f1a17549a2d67c 547 Pfam PF01425 Amidase 72 522 2.6E-101 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_10305 3a0a036a43201c2706f1a17549a2d67c 547 Gene3D G3DSA:3.90.1300.10 46 544 8.1E-151 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_10305 3a0a036a43201c2706f1a17549a2d67c 547 SUPERFAMILY SSF75304 50 538 1.31E-122 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_29260 698c9e1947de3c9f0db0585759058527 79 SUPERFAMILY SSF82697 3 77 7.5E-23 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29260 698c9e1947de3c9f0db0585759058527 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 74 1.0E-21 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_29260 698c9e1947de3c9f0db0585759058527 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 75 3.0E-15 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_29260 698c9e1947de3c9f0db0585759058527 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 1.7E-25 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_29260 698c9e1947de3c9f0db0585759058527 79 Gene3D G3DSA:3.30.1280.10 2 79 1.8E-25 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UA74_29260 698c9e1947de3c9f0db0585759058527 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 19.962 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UA74_10555 ee39dad7054b63050fe2f088cf53c59c 600 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 392 510 4.6E-30 T 12-10-2018 IPR025299 CstA, C-terminal domain UA74_10555 ee39dad7054b63050fe2f088cf53c59c 600 Pfam PF02554 Carbon starvation protein CstA 1 348 7.2E-112 T 12-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 UA74_16830 5804da217d3deac841ca2b72d8ac870a 201 SUPERFAMILY SSF48498 91 178 6.67E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_16830 5804da217d3deac841ca2b72d8ac870a 201 Pfam PF13305 WHG domain 94 175 4.8E-10 T 12-10-2018 IPR025996 WHG domain UA74_16830 5804da217d3deac841ca2b72d8ac870a 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 9.2E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_16830 5804da217d3deac841ca2b72d8ac870a 201 SUPERFAMILY SSF46689 8 81 4.0E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_16830 5804da217d3deac841ca2b72d8ac870a 201 Gene3D G3DSA:1.10.357.10 4 198 2.1E-52 T 12-10-2018 UA74_08955 88b2c05d396bfecab053387b462cbf9c 187 SUPERFAMILY SSF55194 5 186 4.19E-67 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 UA74_08955 88b2c05d396bfecab053387b462cbf9c 187 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 187 1.1E-63 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 UA74_08955 88b2c05d396bfecab053387b462cbf9c 187 Pfam PF01765 Ribosome recycling factor 23 185 1.4E-59 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 UA74_08955 88b2c05d396bfecab053387b462cbf9c 187 Hamap MF_00040 Ribosome-recycling factor [frr]. 5 187 26.428 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 UA74_08955 88b2c05d396bfecab053387b462cbf9c 187 Gene3D G3DSA:3.30.1360.40 33 107 4.6E-64 T 12-10-2018 UA74_08955 88b2c05d396bfecab053387b462cbf9c 187 Gene3D G3DSA:1.10.132.20 14 184 4.6E-64 T 12-10-2018 UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 Gene3D G3DSA:1.20.120.530 87 226 4.0E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 Gene3D G3DSA:1.10.10.10 9 83 1.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 SMART SM00895 93 217 3.6E-16 T 12-10-2018 IPR011711 GntR, C-terminal UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 SUPERFAMILY SSF48008 89 224 1.12E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 SMART SM00345 25 83 1.4E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 Pfam PF07729 FCD domain 93 215 9.9E-22 T 12-10-2018 IPR011711 GntR, C-terminal UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 SUPERFAMILY SSF46785 16 108 1.52E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 3.3E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 3.3E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_11635 70a2bfc1233e56bfe42f786a24f77b4a 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 4.9E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 Gene3D G3DSA:1.10.10.10 519 657 5.4E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 Gene3D G3DSA:1.20.1250.20 272 507 3.4E-18 T 12-10-2018 UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 498 2.8E-84 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 PRINTS PR01035 Tetracycline resistance protein signature 145 167 3.1E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 PRINTS PR01035 Tetracycline resistance protein signature 31 47 3.1E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 SUPERFAMILY SSF103473 210 502 8.76E-31 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 SUPERFAMILY SSF103473 11 195 6.54E-45 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 SUPERFAMILY SSF46785 535 650 6.81E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 Pfam PF07690 Major Facilitator Superfamily 25 417 2.7E-53 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_04910 b27d21ad4c04edc57a4efef831a7fb6b 669 Gene3D G3DSA:1.20.1720.10 22 230 3.8E-54 T 12-10-2018 UA74_08190 182334e83ae9962d5584fe989caed1b7 442 Pfam PF13416 Bacterial extracellular solute-binding protein 66 362 1.5E-12 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_08190 182334e83ae9962d5584fe989caed1b7 442 Gene3D G3DSA:3.40.190.10 149 408 3.7E-35 T 12-10-2018 UA74_08190 182334e83ae9962d5584fe989caed1b7 442 Gene3D G3DSA:3.40.190.10 95 373 3.7E-35 T 12-10-2018 UA74_08190 182334e83ae9962d5584fe989caed1b7 442 SUPERFAMILY SSF53850 43 406 2.57E-36 T 12-10-2018 UA74_13180 49f22701db2e9267fce6c1f0c2eaeff6 618 Gene3D G3DSA:3.40.50.300 292 486 1.2E-6 T 12-10-2018 UA74_13180 49f22701db2e9267fce6c1f0c2eaeff6 618 Pfam PF09818 Predicted ATPase of the ABC class 32 482 1.2E-161 T 12-10-2018 IPR019195 ABC transporter, ATPase, putative UA74_13180 49f22701db2e9267fce6c1f0c2eaeff6 618 SUPERFAMILY SSF52540 284 472 2.7E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01090 ceddd35172fdca5be38deae952df0589 421 Pfam PF00696 Amino acid kinase family 3 231 7.1E-53 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UA74_01090 ceddd35172fdca5be38deae952df0589 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UA74_01090 ceddd35172fdca5be38deae952df0589 421 Pfam PF01842 ACT domain 268 329 1.1E-10 T 12-10-2018 IPR002912 ACT domain UA74_01090 ceddd35172fdca5be38deae952df0589 421 PIRSF PIRSF000726 1 61 3.2E-21 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UA74_01090 ceddd35172fdca5be38deae952df0589 421 PIRSF PIRSF000726 59 414 1.8E-124 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UA74_01090 ceddd35172fdca5be38deae952df0589 421 Gene3D G3DSA:3.30.2130.10 250 421 1.9E-64 T 12-10-2018 UA74_01090 ceddd35172fdca5be38deae952df0589 421 Pfam PF13840 ACT domain 341 403 2.6E-15 T 12-10-2018 IPR027795 CASTOR, ACT domain UA74_01090 ceddd35172fdca5be38deae952df0589 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 406 5.1E-115 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UA74_01090 ceddd35172fdca5be38deae952df0589 421 SUPERFAMILY SSF53633 4 244 1.11E-70 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UA74_01090 ceddd35172fdca5be38deae952df0589 421 SUPERFAMILY SSF55021 251 330 2.05E-17 T 12-10-2018 UA74_01090 ceddd35172fdca5be38deae952df0589 421 Gene3D G3DSA:3.40.1160.10 1 249 8.9E-88 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UA74_01090 ceddd35172fdca5be38deae952df0589 421 SUPERFAMILY SSF55021 334 408 9.92E-22 T 12-10-2018 UA74_17180 4d7d4e646d0ec18ece0e799f37eabaf7 352 SUPERFAMILY SSF81345 16 345 4.18E-83 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_17180 4d7d4e646d0ec18ece0e799f37eabaf7 352 Pfam PF01032 FecCD transport family 26 345 1.8E-96 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_17180 4d7d4e646d0ec18ece0e799f37eabaf7 352 Gene3D G3DSA:1.10.3470.10 14 350 1.7E-106 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_17075 edf15dc095dfa3021d8346977ffcc42d 198 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_17075 edf15dc095dfa3021d8346977ffcc42d 198 PRINTS PR00502 NUDIX hydrolase family signature 44 58 4.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_17075 edf15dc095dfa3021d8346977ffcc42d 198 PRINTS PR00502 NUDIX hydrolase family signature 58 73 4.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_17075 edf15dc095dfa3021d8346977ffcc42d 198 Pfam PF00293 NUDIX domain 14 140 2.8E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_17075 edf15dc095dfa3021d8346977ffcc42d 198 SUPERFAMILY SSF55811 13 144 1.49E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_17075 edf15dc095dfa3021d8346977ffcc42d 198 Gene3D G3DSA:3.90.79.10 3 145 6.0E-36 T 12-10-2018 UA74_01880 9a708d83069ea0c2cc56b7107ecf167b 227 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 130 219 1.3E-10 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain UA74_01880 9a708d83069ea0c2cc56b7107ecf167b 227 Gene3D G3DSA:3.30.70.2390 129 217 3.1E-30 T 12-10-2018 UA74_23845 d720ed06769926919c8c580cd2640d1b 91 SMART SM00421 28 85 1.4E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23845 d720ed06769926919c8c580cd2640d1b 91 SUPERFAMILY SSF46894 18 91 2.24E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_23845 d720ed06769926919c8c580cd2640d1b 91 Pfam PF00196 Bacterial regulatory proteins, luxR family 30 85 6.5E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23845 d720ed06769926919c8c580cd2640d1b 91 Gene3D G3DSA:1.10.10.10 30 91 2.0E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_06700 021ffa78ee67205ebd7451b4f6bdf82f 331 SUPERFAMILY SSF103481 224 321 5.1E-9 T 12-10-2018 UA74_06700 021ffa78ee67205ebd7451b4f6bdf82f 331 Pfam PF00892 EamA-like transporter family 187 314 2.7E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_27410 c72b06909cbfd27f6bbe45a6f5b385c4 324 Gene3D G3DSA:1.10.10.10 1 62 2.0E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27410 c72b06909cbfd27f6bbe45a6f5b385c4 324 SUPERFAMILY SSF46785 2 57 3.21E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_27410 c72b06909cbfd27f6bbe45a6f5b385c4 324 Pfam PF13280 WYL domain 146 316 3.6E-30 T 12-10-2018 IPR026881 WYL domain UA74_27410 c72b06909cbfd27f6bbe45a6f5b385c4 324 PIRSF PIRSF016838 69 323 9.8E-13 T 12-10-2018 IPR028349 Protein PafC UA74_27410 c72b06909cbfd27f6bbe45a6f5b385c4 324 PIRSF PIRSF016838 1 52 4.6E-5 T 12-10-2018 IPR028349 Protein PafC UA74_27410 c72b06909cbfd27f6bbe45a6f5b385c4 324 Pfam PF08279 HTH domain 10 57 3.1E-14 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 SUPERFAMILY SSF46785 2 50 8.47E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 ProSitePatterns PS00519 AsnC-type HTH domain signature. 8 34 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 Pfam PF01037 Lrp/AsnC ligand binding domain 74 126 3.6E-10 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 17 2.9E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 36 2.9E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 Gene3D G3DSA:3.30.70.920 41 131 3.4E-15 T 12-10-2018 UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 Gene3D G3DSA:1.10.10.10 1 40 1.8E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 SMART SM00344 2 97 3.5E-20 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 Pfam PF13404 AsnC-type helix-turn-helix domain 3 30 1.4E-9 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UA74_02655 162a988b0176b5e35ab53b92a639bd4e 149 SUPERFAMILY SSF54909 53 135 6.44E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 219 1.0E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 SUPERFAMILY SSF46894 153 221 1.94E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 Pfam PF00072 Response regulator receiver domain 10 121 3.8E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 Gene3D G3DSA:3.40.50.12740 8 224 6.9E-62 T 12-10-2018 UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 SMART SM00448 8 121 3.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 SUPERFAMILY SSF52172 7 134 9.11E-33 T 12-10-2018 IPR011006 CheY-like superfamily UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 SMART SM00421 163 220 5.6E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 3.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 3.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05330 eb996d84867768f3c99810b4dc70c14c 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 3.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_22465 75cb6afeb52e376d159f8de32729170f 484 Pfam PF14559 Tetratricopeptide repeat 47 90 2.9E-7 T 12-10-2018 UA74_22465 75cb6afeb52e376d159f8de32729170f 484 SUPERFAMILY SSF48452 7 114 7.59E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_22465 75cb6afeb52e376d159f8de32729170f 484 Gene3D G3DSA:1.25.40.10 4 231 1.8E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_22465 75cb6afeb52e376d159f8de32729170f 484 SMART SM00028 36 69 3.4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_22465 75cb6afeb52e376d159f8de32729170f 484 SMART SM00028 2 35 30.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_22465 75cb6afeb52e376d159f8de32729170f 484 SMART SM00028 146 179 80.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_22465 75cb6afeb52e376d159f8de32729170f 484 SUPERFAMILY SSF48452 71 224 1.57E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_14570 c377283fe4a0a80002645deb9272d2b6 340 Pfam PF13354 Beta-lactamase enzyme family 90 283 9.2E-36 T 12-10-2018 UA74_14570 c377283fe4a0a80002645deb9272d2b6 340 Gene3D G3DSA:3.40.710.10 42 310 5.1E-35 T 12-10-2018 UA74_14570 c377283fe4a0a80002645deb9272d2b6 340 SUPERFAMILY SSF56601 55 290 1.97E-23 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_12780 570d6cf079ea8292407dc45836111956 885 SUPERFAMILY SSF158745 552 869 3.01E-21 T 12-10-2018 UA74_12780 570d6cf079ea8292407dc45836111956 885 SMART SM01260 550 875 5.5E-6 T 12-10-2018 IPR007822 Lanthionine synthetase C-like UA74_12780 570d6cf079ea8292407dc45836111956 885 Gene3D G3DSA:3.30.200.20 213 310 3.0E-19 T 12-10-2018 UA74_12780 570d6cf079ea8292407dc45836111956 885 Gene3D G3DSA:1.10.510.10 311 427 3.0E-19 T 12-10-2018 UA74_12780 570d6cf079ea8292407dc45836111956 885 SUPERFAMILY SSF56112 221 405 4.65E-16 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_12780 570d6cf079ea8292407dc45836111956 885 Gene3D G3DSA:1.50.10.10 516 711 7.3E-6 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_26575 006fc6134fdf9bcec16c770e9e9c4f44 367 SUPERFAMILY SSF53697 68 354 7.78E-43 T 12-10-2018 UA74_26575 006fc6134fdf9bcec16c770e9e9c4f44 367 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 203 354 5.9E-9 T 12-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 UA74_13480 4f162b9e600b29782f77358a562644e1 404 Gene3D G3DSA:1.20.140.10 248 402 1.4E-37 T 12-10-2018 UA74_13480 4f162b9e600b29782f77358a562644e1 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 235 1.3E-19 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UA74_13480 4f162b9e600b29782f77358a562644e1 404 Gene3D G3DSA:1.10.540.10 1 131 7.6E-45 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_13480 4f162b9e600b29782f77358a562644e1 404 SUPERFAMILY SSF56645 2 260 5.63E-59 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_13480 4f162b9e600b29782f77358a562644e1 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 129 1.5E-12 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UA74_13480 4f162b9e600b29782f77358a562644e1 404 SUPERFAMILY SSF47203 245 398 7.25E-42 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_13480 4f162b9e600b29782f77358a562644e1 404 Gene3D G3DSA:2.40.110.10 132 247 1.9E-44 T 12-10-2018 UA74_13480 4f162b9e600b29782f77358a562644e1 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 397 4.3E-37 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_22295 44fa61753ca8e31a751219d457acd8a8 180 Gene3D G3DSA:3.40.50.9100 14 170 3.2E-34 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_22295 44fa61753ca8e31a751219d457acd8a8 180 Pfam PF01220 Dehydroquinase class II 19 163 8.6E-31 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_22295 44fa61753ca8e31a751219d457acd8a8 180 PIRSF PIRSF001399 16 169 1.3E-28 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_22295 44fa61753ca8e31a751219d457acd8a8 180 SUPERFAMILY SSF52304 19 169 7.85E-30 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UA74_22295 44fa61753ca8e31a751219d457acd8a8 180 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 20 138 1.0E-16 T 12-10-2018 UA74_27735 dc3ac1fea959b2a9b9000a6252ee2cc8 468 Pfam PF05977 Transmembrane secretion effector 10 412 1.3E-26 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_27735 dc3ac1fea959b2a9b9000a6252ee2cc8 468 Gene3D G3DSA:1.20.1250.20 5 399 9.2E-37 T 12-10-2018 UA74_27735 dc3ac1fea959b2a9b9000a6252ee2cc8 468 SUPERFAMILY SSF103473 8 400 2.35E-47 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_29520 0c8e7605b734c5a404f9ce258ad4f8da 245 SUPERFAMILY SSF52540 28 240 4.85E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29520 0c8e7605b734c5a404f9ce258ad4f8da 245 Pfam PF00005 ABC transporter 42 189 2.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_29520 0c8e7605b734c5a404f9ce258ad4f8da 245 Gene3D G3DSA:3.40.50.300 24 244 4.5E-63 T 12-10-2018 UA74_29520 0c8e7605b734c5a404f9ce258ad4f8da 245 SMART SM00382 50 238 1.4E-21 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28190 d5d1e0521c69d6d460da380c99dd23cc 269 Gene3D G3DSA:3.40.630.30 33 251 7.8E-21 T 12-10-2018 UA74_28190 d5d1e0521c69d6d460da380c99dd23cc 269 Pfam PF08445 FR47-like protein 183 245 5.0E-8 T 12-10-2018 IPR013653 FR47-like GO:0016747 UA74_28190 d5d1e0521c69d6d460da380c99dd23cc 269 SUPERFAMILY SSF55729 128 243 9.17E-13 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 Pfam PF13492 GAF domain 295 427 2.5E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 SMART SM00052 607 852 4.8E-106 T 12-10-2018 IPR001633 EAL domain UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 435 589 2.6E-14 T 12-10-2018 IPR000160 GGDEF domain UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 SUPERFAMILY SSF55781 294 436 1.74E-12 T 12-10-2018 UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 SUPERFAMILY SSF55073 443 591 1.96E-22 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 Gene3D G3DSA:3.20.20.450 610 861 2.1E-92 T 12-10-2018 IPR035919 EAL domain superfamily UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 SMART SM00267 427 600 3.9E-24 T 12-10-2018 IPR000160 GGDEF domain UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 Gene3D G3DSA:3.30.70.270 440 609 1.2E-29 T 12-10-2018 UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 Gene3D G3DSA:3.30.450.40 287 436 7.9E-15 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 SUPERFAMILY SSF141868 614 860 1.96E-84 T 12-10-2018 IPR035919 EAL domain superfamily UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 SMART SM00065 290 435 2.0E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 Pfam PF00563 EAL domain 614 847 2.1E-69 T 12-10-2018 IPR001633 EAL domain UA74_02790 585cf2b441e4dfce933639b7cde6a1bd 877 Pfam PF00990 Diguanylate cyclase, GGDEF domain 438 589 6.8E-21 T 12-10-2018 IPR000160 GGDEF domain UA74_30270 f7088e7cba2f9452eca05e236fdb653b 440 Gene3D G3DSA:3.40.640.10 83 305 5.2E-136 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_30270 f7088e7cba2f9452eca05e236fdb653b 440 Gene3D G3DSA:3.90.1150.10 36 410 5.2E-136 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_30270 f7088e7cba2f9452eca05e236fdb653b 440 Pfam PF00155 Aminotransferase class I and II 61 407 1.6E-40 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_30270 f7088e7cba2f9452eca05e236fdb653b 440 SUPERFAMILY SSF53383 23 413 9.18E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 SUPERFAMILY SSF54534 83 157 1.7E-11 T 12-10-2018 UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 156 1.5E-13 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 Pfam PF03449 Transcription elongation factor, N-terminal 8 76 2.3E-25 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 SUPERFAMILY SSF46557 7 78 3.01E-23 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 27.95 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 Gene3D G3DSA:1.10.287.180 5 76 9.7E-24 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 PIRSF PIRSF006092 1 160 2.5E-31 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 Gene3D G3DSA:3.10.50.30 80 161 8.6E-10 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 UA74_04015 eaf754b71d4a7142746f9cae51d7b602 162 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 50 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 UA74_05015 ad9a46c94af1f5196bc8624f43c46272 100 Gene3D G3DSA:2.10.260.10 9 52 5.4E-8 T 12-10-2018 UA74_05015 ad9a46c94af1f5196bc8624f43c46272 100 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 17 53 1.1E-8 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UA74_05015 ad9a46c94af1f5196bc8624f43c46272 100 SMART SM00966 14 58 1.1E-6 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UA74_05015 ad9a46c94af1f5196bc8624f43c46272 100 SUPERFAMILY SSF89447 17 77 7.32E-8 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily UA74_05015 ad9a46c94af1f5196bc8624f43c46272 100 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 18 50 6.3E-6 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UA74_21480 84158ccbf3a50488cbf7a4a1a7af46ed 382 SUPERFAMILY SSF56349 186 376 1.18E-53 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_21480 84158ccbf3a50488cbf7a4a1a7af46ed 382 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 81 378 53.971 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD UA74_21480 84158ccbf3a50488cbf7a4a1a7af46ed 382 Pfam PF00589 Phage integrase family 193 362 2.2E-45 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_21480 84158ccbf3a50488cbf7a4a1a7af46ed 382 SUPERFAMILY SSF47823 82 176 1.94E-15 T 12-10-2018 UA74_21480 84158ccbf3a50488cbf7a4a1a7af46ed 382 Gene3D G3DSA:1.10.443.10 191 372 2.0E-59 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_21480 84158ccbf3a50488cbf7a4a1a7af46ed 382 Gene3D G3DSA:1.10.150.130 79 179 3.5E-17 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_21480 84158ccbf3a50488cbf7a4a1a7af46ed 382 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 82 170 6.0E-20 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_22435 b9481466dba450a8ced81bb4f2bb91fe 286 SUPERFAMILY SSF56281 58 230 1.02E-20 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_22435 b9481466dba450a8ced81bb4f2bb91fe 286 Pfam PF00753 Metallo-beta-lactamase superfamily 59 199 1.3E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_22435 b9481466dba450a8ced81bb4f2bb91fe 286 Gene3D G3DSA:3.60.15.10 45 239 3.3E-20 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_22435 b9481466dba450a8ced81bb4f2bb91fe 286 SMART SM00849 55 225 1.6E-9 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_25005 01914428187c38cedd6015d4d43df387 375 Pfam PF02595 Glycerate kinase family 3 372 5.9E-109 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_25005 01914428187c38cedd6015d4d43df387 375 SUPERFAMILY SSF110738 1 372 1.44E-96 T 12-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 UA74_25005 01914428187c38cedd6015d4d43df387 375 Gene3D G3DSA:3.40.50.10350 1 358 4.7E-103 T 12-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold UA74_25005 01914428187c38cedd6015d4d43df387 375 PIRSF PIRSF006078 1 374 2.2E-105 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_25005 01914428187c38cedd6015d4d43df387 375 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 372 9.0E-99 T 12-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UA74_25005 01914428187c38cedd6015d4d43df387 375 Gene3D G3DSA:3.90.1510.10 42 275 4.7E-103 T 12-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 UA74_15550 ffba46459e2b52ca0cd749c392e41338 211 Pfam PF13460 NAD(P)H-binding 7 192 1.3E-36 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_15550 ffba46459e2b52ca0cd749c392e41338 211 Gene3D G3DSA:3.40.50.720 2 209 5.3E-42 T 12-10-2018 UA74_15550 ffba46459e2b52ca0cd749c392e41338 211 SUPERFAMILY SSF51735 1 205 3.81E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25935 cb7b996f4e9d467964c51e9672e36834 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 4 74 3.0E-31 T 12-10-2018 UA74_25935 cb7b996f4e9d467964c51e9672e36834 168 SUPERFAMILY SSF55021 81 162 3.85E-26 T 12-10-2018 UA74_25935 cb7b996f4e9d467964c51e9672e36834 168 Gene3D G3DSA:3.30.70.260 1 79 3.3E-36 T 12-10-2018 UA74_25935 cb7b996f4e9d467964c51e9672e36834 168 Gene3D G3DSA:3.30.70.1150 84 164 5.3E-30 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal UA74_25935 cb7b996f4e9d467964c51e9672e36834 168 SUPERFAMILY SSF55021 3 76 1.17E-23 T 12-10-2018 UA74_25935 cb7b996f4e9d467964c51e9672e36834 168 Pfam PF01842 ACT domain 4 69 2.6E-18 T 12-10-2018 IPR002912 ACT domain UA74_25935 cb7b996f4e9d467964c51e9672e36834 168 Pfam PF10369 Small subunit of acetolactate synthase 85 158 1.2E-28 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UA74_25935 cb7b996f4e9d467964c51e9672e36834 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 9.6E-64 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UA74_29670 e5772165f8ab61620dd3f0deea6f44f7 199 SUPERFAMILY SSF75217 33 192 4.77E-38 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_29670 e5772165f8ab61620dd3f0deea6f44f7 199 Pfam PF00588 SpoU rRNA Methylase family 50 186 2.0E-24 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_29670 e5772165f8ab61620dd3f0deea6f44f7 199 Gene3D G3DSA:3.40.1280.10 32 198 1.9E-34 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_17370 64e8f46e493415ef0f140814b382a064 609 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 75 268 9.3E-10 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_17370 64e8f46e493415ef0f140814b382a064 609 SUPERFAMILY SSF51905 76 529 4.53E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17370 64e8f46e493415ef0f140814b382a064 609 Gene3D G3DSA:3.50.50.60 420 603 2.9E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17370 64e8f46e493415ef0f140814b382a064 609 Gene3D G3DSA:3.50.50.60 69 379 5.6E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_26800 f5eab08174810628bed511ad33f1cbe2 267 Pfam PF00483 Nucleotidyl transferase 10 234 2.3E-28 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_26800 f5eab08174810628bed511ad33f1cbe2 267 SUPERFAMILY SSF53448 5 234 9.81E-58 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_26800 f5eab08174810628bed511ad33f1cbe2 267 Gene3D G3DSA:3.90.550.10 6 238 1.3E-59 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_19390 848aeb95433522d21187abe9830b4e4d 393 SUPERFAMILY SSF81345 66 388 2.22E-77 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_19390 848aeb95433522d21187abe9830b4e4d 393 Pfam PF01032 FecCD transport family 78 387 2.8E-90 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_19390 848aeb95433522d21187abe9830b4e4d 393 Gene3D G3DSA:1.10.3470.10 65 391 6.4E-94 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_17115 ce1220ff09c23f162fd63ed4a2a955ce 433 SUPERFAMILY SSF103473 21 415 3.4E-43 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_17115 ce1220ff09c23f162fd63ed4a2a955ce 433 Pfam PF05977 Transmembrane secretion effector 21 422 2.4E-26 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_17115 ce1220ff09c23f162fd63ed4a2a955ce 433 Gene3D G3DSA:1.20.1250.20 18 413 2.6E-39 T 12-10-2018 UA74_18665 50a3c196594fd1bb1a36f3151c613f08 312 Pfam PF02779 Transketolase, pyrimidine binding domain 56 173 4.7E-16 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_18665 50a3c196594fd1bb1a36f3151c613f08 312 SUPERFAMILY SSF52922 187 307 2.49E-12 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_18665 50a3c196594fd1bb1a36f3151c613f08 312 SMART SM00861 16 181 1.2E-14 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_18665 50a3c196594fd1bb1a36f3151c613f08 312 SUPERFAMILY SSF52518 17 173 9.64E-29 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_18665 50a3c196594fd1bb1a36f3151c613f08 312 Gene3D G3DSA:3.40.50.920 187 309 6.4E-13 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_18665 50a3c196594fd1bb1a36f3151c613f08 312 Gene3D G3DSA:3.40.50.970 15 183 2.2E-32 T 12-10-2018 UA74_09460 5c270bf223f6623dbc2d938427663979 69 TIGRFAM TIGR03898 lanti_MRSA_kill: type 2 lantibiotic, mersacidin/lichenicidin family 2 37 6.8E-7 T 12-10-2018 IPR027635 Type 2 lantibiotic, leader peptide domain GO:0042742 UA74_26150 60e22a4b6cf17fee7e86152934390bc2 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 6.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_26150 60e22a4b6cf17fee7e86152934390bc2 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_26150 60e22a4b6cf17fee7e86152934390bc2 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_26150 60e22a4b6cf17fee7e86152934390bc2 186 SUPERFAMILY SSF46689 3 69 3.34E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_26150 60e22a4b6cf17fee7e86152934390bc2 186 Gene3D G3DSA:1.10.357.10 2 185 2.0E-34 T 12-10-2018 UA74_07550 43c629e26998f5993403ec963ad76c2f 152 Pfam PF12680 SnoaL-like domain 17 128 1.0E-13 T 12-10-2018 IPR037401 SnoaL-like domain UA74_07550 43c629e26998f5993403ec963ad76c2f 152 SUPERFAMILY SSF54427 10 142 1.58E-27 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_07550 43c629e26998f5993403ec963ad76c2f 152 Gene3D G3DSA:3.10.450.50 8 148 5.8E-31 T 12-10-2018 UA74_08255 5253a72cc803d48347d64d9411dafd59 143 SUPERFAMILY SSF81301 7 117 2.29E-38 T 12-10-2018 UA74_08255 5253a72cc803d48347d64d9411dafd59 143 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 109 23.214 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS UA74_08255 5253a72cc803d48347d64d9411dafd59 143 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 14 108 1.3E-31 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS UA74_08255 5253a72cc803d48347d64d9411dafd59 143 Gene3D G3DSA:3.30.460.10 1 112 1.9E-39 T 12-10-2018 UA74_08255 5253a72cc803d48347d64d9411dafd59 143 Pfam PF02410 Ribosomal silencing factor during starvation 15 108 6.6E-23 T 12-10-2018 UA74_23335 9c4f31fce8d15f9f2087b91074478a4a 128 Pfam PF14079 Domain of unknown function (DUF4260) 23 123 4.1E-28 T 12-10-2018 IPR025356 Protein of unknown function DUF4260 UA74_10895 c9ea574ad8177b633f89327bf1670170 327 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 1.6E-22 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 UA74_10895 c9ea574ad8177b633f89327bf1670170 327 Gene3D G3DSA:3.40.50.720 2 163 1.6E-42 T 12-10-2018 UA74_10895 c9ea574ad8177b633f89327bf1670170 327 SUPERFAMILY SSF48179 164 284 1.36E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_10895 c9ea574ad8177b633f89327bf1670170 327 Gene3D G3DSA:1.10.1040.10 164 290 3.2E-32 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_10895 c9ea574ad8177b633f89327bf1670170 327 SUPERFAMILY SSF51735 6 163 6.81E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_10895 c9ea574ad8177b633f89327bf1670170 327 PIRSF PIRSF000103 1 312 1.1E-70 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_10895 c9ea574ad8177b633f89327bf1670170 327 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 162 7.3E-35 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UA74_15430 aeab2b8c05850a5835d95f108e145c7c 339 SUPERFAMILY SSF51430 1 313 6.42E-92 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_15430 aeab2b8c05850a5835d95f108e145c7c 339 Gene3D G3DSA:3.20.20.100 1 328 7.1E-107 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_15430 aeab2b8c05850a5835d95f108e145c7c 339 Pfam PF00248 Aldo/keto reductase family 16 313 3.6E-67 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_14685 b27255d22514469495a9e623c1ed9790 257 Gene3D G3DSA:3.40.50.150 25 186 2.1E-20 T 12-10-2018 UA74_14685 b27255d22514469495a9e623c1ed9790 257 Pfam PF13649 Methyltransferase domain 63 160 2.6E-9 T 12-10-2018 UA74_14685 b27255d22514469495a9e623c1ed9790 257 SUPERFAMILY SSF53335 29 244 1.96E-20 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_29590 43157ef17d92ba3626a0209c716c5142 551 TIGRFAM TIGR00835 agcS: amino acid carrier protein 67 515 1.7E-107 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_29590 43157ef17d92ba3626a0209c716c5142 551 PRINTS PR00175 Sodium/alanine symporter signature 250 268 1.4E-40 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_29590 43157ef17d92ba3626a0209c716c5142 551 PRINTS PR00175 Sodium/alanine symporter signature 368 386 1.4E-40 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_29590 43157ef17d92ba3626a0209c716c5142 551 PRINTS PR00175 Sodium/alanine symporter signature 423 445 1.4E-40 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_29590 43157ef17d92ba3626a0209c716c5142 551 PRINTS PR00175 Sodium/alanine symporter signature 278 297 1.4E-40 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_29590 43157ef17d92ba3626a0209c716c5142 551 PRINTS PR00175 Sodium/alanine symporter signature 484 504 1.4E-40 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_29590 43157ef17d92ba3626a0209c716c5142 551 PRINTS PR00175 Sodium/alanine symporter signature 139 161 1.4E-40 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_29590 43157ef17d92ba3626a0209c716c5142 551 Pfam PF01235 Sodium:alanine symporter family 103 523 6.9E-126 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UA74_22665 ccd29ea0332bb121183a70357c5e8be2 390 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 246 323 3.8E-24 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_22665 ccd29ea0332bb121183a70357c5e8be2 390 Gene3D G3DSA:3.40.50.300 17 334 3.4E-96 T 12-10-2018 UA74_22665 ccd29ea0332bb121183a70357c5e8be2 390 SUPERFAMILY SSF52540 19 267 5.99E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22665 ccd29ea0332bb121183a70357c5e8be2 390 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22665 ccd29ea0332bb121183a70357c5e8be2 390 Pfam PF00005 ABC transporter 43 196 5.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_22665 ccd29ea0332bb121183a70357c5e8be2 390 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 316 4.2E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_22665 ccd29ea0332bb121183a70357c5e8be2 390 SMART SM00382 52 246 1.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20810 2ba7787bcc696b56c71b797dd6879ad5 252 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_20810 2ba7787bcc696b56c71b797dd6879ad5 252 SUPERFAMILY SSF52540 24 246 1.5E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20810 2ba7787bcc696b56c71b797dd6879ad5 252 Pfam PF00005 ABC transporter 44 194 9.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_20810 2ba7787bcc696b56c71b797dd6879ad5 252 SMART SM00382 53 242 8.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20810 2ba7787bcc696b56c71b797dd6879ad5 252 Gene3D G3DSA:3.40.50.300 22 251 1.3E-62 T 12-10-2018 UA74_06115 04d1ad474442c435f000e59f2387fabc 680 SMART SM00939 396 654 2.4E-36 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_06115 04d1ad474442c435f000e59f2387fabc 680 SUPERFAMILY SSF49785 475 659 4.89E-27 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_06115 04d1ad474442c435f000e59f2387fabc 680 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 408 651 1.5E-29 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_06115 04d1ad474442c435f000e59f2387fabc 680 Gene3D G3DSA:3.40.50.1820 93 284 7.5E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06115 04d1ad474442c435f000e59f2387fabc 680 Gene3D G3DSA:3.40.50.1820 318 444 8.4E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06115 04d1ad474442c435f000e59f2387fabc 680 SUPERFAMILY SSF53474 77 431 1.75E-61 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06115 04d1ad474442c435f000e59f2387fabc 680 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 109 381 2.5E-39 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_20715 ec33e65f671d5eb6bbe79c8a3df4bef5 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 324 3.6E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_10030 649ef2ae87301988ce9e556ed1722f44 540 Pfam PF04715 Anthranilate synthase component I, N terminal region 38 179 8.4E-31 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_10030 649ef2ae87301988ce9e556ed1722f44 540 SUPERFAMILY SSF56322 27 506 8.77E-153 T 12-10-2018 IPR005801 ADC synthase GO:0009058 UA74_10030 649ef2ae87301988ce9e556ed1722f44 540 Pfam PF00425 chorismate binding enzyme 235 497 9.5E-97 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal UA74_10030 649ef2ae87301988ce9e556ed1722f44 540 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 37 505 1.3E-166 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_10030 649ef2ae87301988ce9e556ed1722f44 540 Gene3D G3DSA:3.60.120.10 9 516 1.7E-204 T 12-10-2018 IPR005801 ADC synthase GO:0009058 UA74_10030 649ef2ae87301988ce9e556ed1722f44 540 PRINTS PR00095 Anthranilate synthase component I signature 439 453 2.5E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_10030 649ef2ae87301988ce9e556ed1722f44 540 PRINTS PR00095 Anthranilate synthase component I signature 359 372 2.5E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_10030 649ef2ae87301988ce9e556ed1722f44 540 PRINTS PR00095 Anthranilate synthase component I signature 454 468 2.5E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_10030 649ef2ae87301988ce9e556ed1722f44 540 PRINTS PR00095 Anthranilate synthase component I signature 345 358 2.5E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UA74_14500 a654aa06bc264acf82ba0a59b0f63375 227 Pfam PF03358 NADPH-dependent FMN reductase 10 159 6.8E-30 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_14500 a654aa06bc264acf82ba0a59b0f63375 227 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 10 185 1.5E-62 T 12-10-2018 IPR023932 Uncharacterised protein family, CE1759 UA74_14500 a654aa06bc264acf82ba0a59b0f63375 227 SUPERFAMILY SSF52218 9 167 2.19E-27 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_14500 a654aa06bc264acf82ba0a59b0f63375 227 Gene3D G3DSA:3.40.50.360 4 183 1.6E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_02630 170af7fe197d033806202bdacd331dea 340 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 220 232 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site UA74_02630 170af7fe197d033806202bdacd331dea 340 Pfam PF00348 Polyprenyl synthetase 50 291 2.6E-61 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 UA74_02630 170af7fe197d033806202bdacd331dea 340 Gene3D G3DSA:1.10.600.10 10 340 5.5E-109 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_02630 170af7fe197d033806202bdacd331dea 340 SUPERFAMILY SSF48576 28 339 7.36E-85 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_09540 887944c9e6a0a4e8e2253bc6e1b0bf7a 216 Gene3D G3DSA:3.90.950.20 50 214 2.4E-47 T 12-10-2018 IPR036653 CinA-like, C-terminal UA74_09540 887944c9e6a0a4e8e2253bc6e1b0bf7a 216 SUPERFAMILY SSF142433 60 211 9.42E-42 T 12-10-2018 IPR036653 CinA-like, C-terminal UA74_09540 887944c9e6a0a4e8e2253bc6e1b0bf7a 216 Pfam PF02464 Competence-damaged protein 63 210 3.2E-43 T 12-10-2018 IPR008136 CinA, C-terminal UA74_09540 887944c9e6a0a4e8e2253bc6e1b0bf7a 216 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 68 208 6.6E-32 T 12-10-2018 IPR008136 CinA, C-terminal UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 SUPERFAMILY SSF51126 3 556 2.49E-25 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 Gene3D G3DSA:2.160.20.10 1 115 1.1E-10 T 12-10-2018 IPR012334 Pectin lyase fold UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 358 380 10000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 433 455 31.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 382 404 15.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 459 486 2500.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 290 312 760.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 493 518 1800.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 SMART SM00710 405 432 8100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_28360 ff89652ff1a7404f16e15211097ddd9e 607 Pfam PF13229 Right handed beta helix region 381 532 5.5E-14 T 12-10-2018 IPR039448 Right handed beta helix domain UA74_30255 00b24b1d2ddceb57db778d88ede1168f 109 PIRSF PIRSF000077 2 108 1.0E-44 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_30255 00b24b1d2ddceb57db778d88ede1168f 109 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_30255 00b24b1d2ddceb57db778d88ede1168f 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 2.8E-40 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UA74_30255 00b24b1d2ddceb57db778d88ede1168f 109 SUPERFAMILY SSF52833 5 109 1.48E-40 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_30255 00b24b1d2ddceb57db778d88ede1168f 109 Gene3D G3DSA:3.40.30.10 2 109 1.2E-39 T 12-10-2018 UA74_30255 00b24b1d2ddceb57db778d88ede1168f 109 PRINTS PR00421 Thioredoxin family signature 32 41 5.7E-9 T 12-10-2018 UA74_30255 00b24b1d2ddceb57db778d88ede1168f 109 PRINTS PR00421 Thioredoxin family signature 24 32 5.7E-9 T 12-10-2018 UA74_30255 00b24b1d2ddceb57db778d88ede1168f 109 PRINTS PR00421 Thioredoxin family signature 72 83 5.7E-9 T 12-10-2018 UA74_30255 00b24b1d2ddceb57db778d88ede1168f 109 Pfam PF00085 Thioredoxin 6 107 2.1E-35 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 UA74_12825 ac51d84d0c43fd2a2b9738c5d7de01e1 297 Pfam PF12705 PD-(D/E)XK nuclease superfamily 24 270 5.2E-37 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type UA74_12825 ac51d84d0c43fd2a2b9738c5d7de01e1 297 Gene3D G3DSA:3.90.320.10 19 213 8.3E-6 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal UA74_12825 ac51d84d0c43fd2a2b9738c5d7de01e1 297 SUPERFAMILY SSF52980 44 205 5.36E-10 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_14575 d12bdf13a163799dfcb0a424492e4a8a 210 Gene3D G3DSA:3.40.630.30 2 204 1.9E-64 T 12-10-2018 UA74_14575 d12bdf13a163799dfcb0a424492e4a8a 210 SUPERFAMILY SSF55729 2 186 3.26E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_14575 d12bdf13a163799dfcb0a424492e4a8a 210 Pfam PF00583 Acetyltransferase (GNAT) family 33 182 4.0E-10 T 12-10-2018 IPR000182 GNAT domain UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 Pfam PF00128 Alpha amylase, catalytic domain 200 283 5.9E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 SUPERFAMILY SSF81296 14 138 2.38E-36 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 SUPERFAMILY SSF51445 155 600 1.21E-126 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 Gene3D G3DSA:2.60.40.10 2 149 9.6E-39 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 SUPERFAMILY SSF51011 613 725 5.9E-16 T 12-10-2018 UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 Gene3D G3DSA:2.60.40.1180 616 728 1.2E-11 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 Gene3D G3DSA:3.20.20.80 154 607 4.8E-163 T 12-10-2018 UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 14 724 7.3E-255 T 12-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 18 108 2.3E-16 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_06325 a44a45ed86f0c431d6774d7c31b3206d 732 SMART SM00642 170 593 2.4E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_12650 2e9a344ab383b28f83e57e10cf17737a 242 SUPERFAMILY SSF53697 18 203 4.89E-18 T 12-10-2018 UA74_12650 2e9a344ab383b28f83e57e10cf17737a 242 Pfam PF13580 SIS domain 14 144 5.7E-36 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UA74_12650 2e9a344ab383b28f83e57e10cf17737a 242 Gene3D G3DSA:3.40.50.10490 4 234 3.6E-55 T 12-10-2018 UA74_14430 a0fe6f42aefb94be32a29f24b329bb53 370 SUPERFAMILY SSF81345 43 364 2.48E-70 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_14430 a0fe6f42aefb94be32a29f24b329bb53 370 Pfam PF01032 FecCD transport family 56 364 2.0E-79 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_14430 a0fe6f42aefb94be32a29f24b329bb53 370 Gene3D G3DSA:1.10.3470.10 43 369 2.2E-82 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_22230 9b57e769a6538518a930c1a3a1cb221b 327 Gene3D G3DSA:3.30.1490.20 122 182 3.8E-6 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_22230 9b57e769a6538518a930c1a3a1cb221b 327 Gene3D G3DSA:3.30.470.80 184 288 5.7E-19 T 12-10-2018 UA74_22230 9b57e769a6538518a930c1a3a1cb221b 327 SUPERFAMILY SSF56059 92 281 6.9E-29 T 12-10-2018 UA74_22230 9b57e769a6538518a930c1a3a1cb221b 327 Pfam PF08443 RimK-like ATP-grasp domain 102 279 7.1E-14 T 12-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 UA74_15115 666fe3e8a40f8dc38a371d98d9ed0935 217 SUPERFAMILY SSF46689 9 79 3.34E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_15115 666fe3e8a40f8dc38a371d98d9ed0935 217 Gene3D G3DSA:1.10.10.60 8 64 7.2E-21 T 12-10-2018 UA74_15115 666fe3e8a40f8dc38a371d98d9ed0935 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 7.1E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15115 666fe3e8a40f8dc38a371d98d9ed0935 217 SUPERFAMILY SSF48498 82 206 7.71E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_15115 666fe3e8a40f8dc38a371d98d9ed0935 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15115 666fe3e8a40f8dc38a371d98d9ed0935 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15115 666fe3e8a40f8dc38a371d98d9ed0935 217 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 151 205 1.6E-14 T 12-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type UA74_15115 666fe3e8a40f8dc38a371d98d9ed0935 217 Gene3D G3DSA:1.10.357.10 71 208 1.4E-32 T 12-10-2018 UA74_00680 45da195e8325a6270d0dbbf59e36d71d 395 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 79 2.2E-17 T 12-10-2018 UA74_00680 45da195e8325a6270d0dbbf59e36d71d 395 SUPERFAMILY SSF54373 254 325 2.35E-22 T 12-10-2018 UA74_00680 45da195e8325a6270d0dbbf59e36d71d 395 Pfam PF03275 UDP-galactopyranose mutase 154 361 2.4E-81 T 12-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 UA74_00680 45da195e8325a6270d0dbbf59e36d71d 395 Gene3D G3DSA:3.40.50.720 306 386 5.2E-20 T 12-10-2018 UA74_00680 45da195e8325a6270d0dbbf59e36d71d 395 Gene3D G3DSA:3.40.50.720 3 97 2.8E-33 T 12-10-2018 UA74_00680 45da195e8325a6270d0dbbf59e36d71d 395 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 6 379 3.4E-105 T 12-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 UA74_00680 45da195e8325a6270d0dbbf59e36d71d 395 Gene3D G3DSA:3.40.50.720 152 264 1.7E-25 T 12-10-2018 UA74_00680 45da195e8325a6270d0dbbf59e36d71d 395 SUPERFAMILY SSF51971 6 375 7.65E-46 T 12-10-2018 UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 325 7.7E-22 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 SUPERFAMILY SSF52518 8 178 6.34E-40 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 172 1.7E-43 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 Gene3D G3DSA:3.40.50.970 6 175 1.0E-49 T 12-10-2018 UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 537 8.7E-27 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 SUPERFAMILY SSF52518 365 540 1.22E-40 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 Gene3D G3DSA:3.40.50.970 360 541 4.9E-46 T 12-10-2018 UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 Gene3D G3DSA:3.40.50.1220 182 351 3.8E-34 T 12-10-2018 UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 SUPERFAMILY SSF52467 155 333 2.36E-30 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UA74_07575 2bc0049a2094cc05709f5078b3f38671 541 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 UA74_29750 652c210cb64376542e79c1706b85fae1 663 SUPERFAMILY SSF49319 309 420 1.3E-16 T 12-10-2018 IPR027273 Neocarzinostatin-like UA74_29750 652c210cb64376542e79c1706b85fae1 663 SUPERFAMILY SSF49319 46 180 4.41E-9 T 12-10-2018 IPR027273 Neocarzinostatin-like UA74_29750 652c210cb64376542e79c1706b85fae1 663 SUPERFAMILY SSF49319 187 303 6.38E-8 T 12-10-2018 IPR027273 Neocarzinostatin-like UA74_29750 652c210cb64376542e79c1706b85fae1 663 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 67 - T 12-10-2018 IPR010916 TonB box, conserved site UA74_29750 652c210cb64376542e79c1706b85fae1 663 SUPERFAMILY SSF49319 441 565 1.01E-11 T 12-10-2018 IPR027273 Neocarzinostatin-like UA74_29750 652c210cb64376542e79c1706b85fae1 663 Pfam PF00960 Neocarzinostatin family 311 404 2.3E-7 T 12-10-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 UA74_29750 652c210cb64376542e79c1706b85fae1 663 Gene3D G3DSA:2.60.40.230 307 413 2.6E-9 T 12-10-2018 UA74_18805 2cb4ec17e6f900e465b323b97556719c 140 Gene3D G3DSA:2.30.40.10 1 36 1.8E-5 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_26990 579723d072477271e6c7ab8982a09f4a 150 Gene3D G3DSA:3.10.490.10 2 147 1.2E-39 T 12-10-2018 UA74_26990 579723d072477271e6c7ab8982a09f4a 150 SUPERFAMILY SSF110857 3 120 8.37E-17 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily UA74_26990 579723d072477271e6c7ab8982a09f4a 150 Pfam PF13772 AIG2-like family 59 140 1.9E-21 T 12-10-2018 UA74_29110 0ae9e16219b8866613fffe168ba6967b 370 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 55 369 6.9E-83 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 UA74_29110 0ae9e16219b8866613fffe168ba6967b 370 SUPERFAMILY SSF53850 52 369 1.19E-79 T 12-10-2018 UA74_29110 0ae9e16219b8866613fffe168ba6967b 370 Pfam PF12849 PBP superfamily domain 45 339 6.0E-57 T 12-10-2018 IPR024370 PBP domain UA74_29110 0ae9e16219b8866613fffe168ba6967b 370 PIRSF PIRSF002756 6 370 1.9E-109 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 UA74_29110 0ae9e16219b8866613fffe168ba6967b 370 Gene3D G3DSA:3.40.190.10 134 311 5.0E-105 T 12-10-2018 UA74_29110 0ae9e16219b8866613fffe168ba6967b 370 Gene3D G3DSA:3.40.190.10 57 356 5.0E-105 T 12-10-2018 UA74_12575 0b2c1e8c0cc6f887a639cfa04af549d4 399 Pfam PF05834 Lycopene cyclase protein 3 354 5.6E-59 T 12-10-2018 UA74_12575 0b2c1e8c0cc6f887a639cfa04af549d4 399 Gene3D G3DSA:3.50.50.60 3 303 4.8E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_12575 0b2c1e8c0cc6f887a639cfa04af549d4 399 Gene3D G3DSA:3.30.9.50 36 242 4.8E-13 T 12-10-2018 UA74_12575 0b2c1e8c0cc6f887a639cfa04af549d4 399 TIGRFAM TIGR01790 carotene-cycl: lycopene cyclase family protein 3 378 2.2E-67 T 12-10-2018 IPR010108 Lycopene cyclase, beta/epsilon GO:0016117|GO:0016705 UA74_12575 0b2c1e8c0cc6f887a639cfa04af549d4 399 SUPERFAMILY SSF51905 2 316 5.61E-21 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_24060 6f0fd3e9e4b720fa9c6a47e548987a7f 507 ProSitePatterns PS00080 Multicopper oxidases signature 2. 475 486 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 UA74_24060 6f0fd3e9e4b720fa9c6a47e548987a7f 507 SUPERFAMILY SSF49503 63 188 4.76E-33 T 12-10-2018 IPR008972 Cupredoxin UA74_24060 6f0fd3e9e4b720fa9c6a47e548987a7f 507 Gene3D G3DSA:2.60.40.420 187 357 4.5E-41 T 12-10-2018 IPR008972 Cupredoxin UA74_24060 6f0fd3e9e4b720fa9c6a47e548987a7f 507 Pfam PF07732 Multicopper oxidase 74 188 2.6E-32 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_24060 6f0fd3e9e4b720fa9c6a47e548987a7f 507 SUPERFAMILY SSF49503 384 492 2.72E-29 T 12-10-2018 IPR008972 Cupredoxin UA74_24060 6f0fd3e9e4b720fa9c6a47e548987a7f 507 Pfam PF07731 Multicopper oxidase 380 494 9.4E-23 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_24060 6f0fd3e9e4b720fa9c6a47e548987a7f 507 SUPERFAMILY SSF49503 195 320 7.71E-23 T 12-10-2018 IPR008972 Cupredoxin UA74_24060 6f0fd3e9e4b720fa9c6a47e548987a7f 507 Gene3D G3DSA:2.60.40.420 47 185 5.4E-45 T 12-10-2018 IPR008972 Cupredoxin UA74_24060 6f0fd3e9e4b720fa9c6a47e548987a7f 507 Gene3D G3DSA:2.60.40.420 369 498 3.5E-41 T 12-10-2018 IPR008972 Cupredoxin UA74_12895 8cde877bea57ba0b211cd4ae9873af40 161 Gene3D G3DSA:3.40.50.620 4 156 8.2E-32 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_12895 8cde877bea57ba0b211cd4ae9873af40 161 Pfam PF00582 Universal stress protein family 11 147 4.0E-18 T 12-10-2018 IPR006016 UspA UA74_12895 8cde877bea57ba0b211cd4ae9873af40 161 SUPERFAMILY SSF52402 11 151 3.77E-24 T 12-10-2018 UA74_12895 8cde877bea57ba0b211cd4ae9873af40 161 PRINTS PR01438 Universal stress protein signature 8 26 2.5E-9 T 12-10-2018 IPR006015 Universal stress protein A UA74_12895 8cde877bea57ba0b211cd4ae9873af40 161 PRINTS PR01438 Universal stress protein signature 125 147 2.5E-9 T 12-10-2018 IPR006015 Universal stress protein A UA74_17980 9c384588b721cadbaeb8a7148a3572b0 100 SUPERFAMILY SSF50475 4 63 1.07E-6 T 12-10-2018 UA74_17980 9c384588b721cadbaeb8a7148a3572b0 100 Gene3D G3DSA:2.30.110.10 1 86 3.1E-8 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_17980 9c384588b721cadbaeb8a7148a3572b0 100 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 15 56 3.1E-4 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_09040 67b40e0b7bd19587fe60f8b5a623af59 551 SUPERFAMILY SSF52317 197 403 2.08E-36 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_09040 67b40e0b7bd19587fe60f8b5a623af59 551 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 537 176.129 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UA74_09040 67b40e0b7bd19587fe60f8b5a623af59 551 Gene3D G3DSA:3.40.50.300 9 249 2.4E-52 T 12-10-2018 UA74_09040 67b40e0b7bd19587fe60f8b5a623af59 551 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 264 480 4.9E-43 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UA74_09040 67b40e0b7bd19587fe60f8b5a623af59 551 SUPERFAMILY SSF52540 9 244 7.97E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_09040 67b40e0b7bd19587fe60f8b5a623af59 551 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 10 528 3.2E-142 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UA74_09040 67b40e0b7bd19587fe60f8b5a623af59 551 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 10 236 2.4E-24 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain UA74_09040 67b40e0b7bd19587fe60f8b5a623af59 551 Gene3D G3DSA:3.40.50.880 265 404 1.6E-24 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_21870 9b7c7f8b5dafe96798080a744f2ea98b 302 Pfam PF14100 Methane oxygenase PmoA 14 295 2.8E-80 T 12-10-2018 IPR029475 Methane oxygenase PmoA UA74_17580 92b700ff4adccfb001aae52dfac53b19 505 SUPERFAMILY SSF51905 5 388 1.6E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17580 92b700ff4adccfb001aae52dfac53b19 505 Gene3D G3DSA:3.30.9.100 45 290 4.4E-139 T 12-10-2018 UA74_17580 92b700ff4adccfb001aae52dfac53b19 505 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 1.2E-9 T 12-10-2018 UA74_17580 92b700ff4adccfb001aae52dfac53b19 505 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 1.2E-9 T 12-10-2018 UA74_17580 92b700ff4adccfb001aae52dfac53b19 505 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 314 1.2E-9 T 12-10-2018 UA74_17580 92b700ff4adccfb001aae52dfac53b19 505 Gene3D G3DSA:3.50.50.60 9 384 4.4E-139 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17580 92b700ff4adccfb001aae52dfac53b19 505 Pfam PF04820 Tryptophan halogenase 103 405 1.5E-56 T 12-10-2018 IPR006905 Flavin-dependent halogenase UA74_17580 92b700ff4adccfb001aae52dfac53b19 505 Pfam PF04820 Tryptophan halogenase 10 97 4.2E-22 T 12-10-2018 IPR006905 Flavin-dependent halogenase UA74_24430 3af5ec15ff5de560df7c5b26913a2c35 246 PIRSF PIRSF006648 2 245 1.8E-19 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_24430 3af5ec15ff5de560df7c5b26913a2c35 246 Pfam PF01061 ABC-2 type transporter 3 213 3.0E-27 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_24430 3af5ec15ff5de560df7c5b26913a2c35 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 6.0E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_24430 3af5ec15ff5de560df7c5b26913a2c35 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 6.0E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_24430 3af5ec15ff5de560df7c5b26913a2c35 246 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 6.0E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_12865 cf965ff127b0408e3f572825128bae12 321 Gene3D G3DSA:3.20.20.100 9 295 9.0E-39 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_12865 cf965ff127b0408e3f572825128bae12 321 Pfam PF00248 Aldo/keto reductase family 50 301 2.0E-20 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_12865 cf965ff127b0408e3f572825128bae12 321 SUPERFAMILY SSF51430 11 305 1.09E-35 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 SUPERFAMILY SSF52949 19 154 4.24E-21 T 12-10-2018 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 SUPERFAMILY SSF53187 176 494 1.91E-106 T 12-10-2018 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 279 300 5.6E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 338 358 5.6E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 316 337 5.6E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 366 381 5.6E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 PRINTS PR00481 Cytosol aminopeptidase signature 257 274 5.6E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 Gene3D G3DSA:3.40.630.10 162 497 3.0E-125 T 12-10-2018 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 182 487 1.0E-113 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 30 145 5.6E-20 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 342 349 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 6 496 33.73 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 UA74_25055 35e59dc81b7cd9929f0e2d07d205fef8 498 Gene3D G3DSA:3.40.220.10 5 157 2.3E-26 T 12-10-2018 UA74_22310 9e3841341eb3277c26bfff6161452784 287 Pfam PF12697 Alpha/beta hydrolase family 33 267 2.3E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22310 9e3841341eb3277c26bfff6161452784 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 4.4E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22310 9e3841341eb3277c26bfff6161452784 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 4.4E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22310 9e3841341eb3277c26bfff6161452784 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 4.4E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22310 9e3841341eb3277c26bfff6161452784 287 Gene3D G3DSA:3.40.50.1820 10 271 2.7E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22310 9e3841341eb3277c26bfff6161452784 287 SUPERFAMILY SSF53474 4 271 5.32E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 Gene3D G3DSA:3.30.300.10 12 252 3.7E-167 T 12-10-2018 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 SUPERFAMILY SSF55973 10 116 6.47E-45 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 278 286 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 PIRSF PIRSF000497 5 402 6.2E-163 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 Pfam PF02772 S-adenosylmethionine synthetase, central domain 131 250 5.1E-43 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 Gene3D G3DSA:3.30.300.10 109 393 3.7E-167 T 12-10-2018 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 9 402 55.338 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 252 391 1.9E-65 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 Gene3D G3DSA:3.30.300.10 18 289 3.7E-167 T 12-10-2018 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 11 108 1.9E-40 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 12 400 1.3E-164 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 133 143 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 SUPERFAMILY SSF55973 252 401 7.85E-66 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_12240 8c64d7fc9c8278bc25f0f978c076fb1c 404 SUPERFAMILY SSF55973 127 251 5.89E-44 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UA74_00720 ec99ce4960fa12e37ebc472c1f420a98 220 Gene3D G3DSA:3.40.50.150 30 210 2.0E-14 T 12-10-2018 UA74_00720 ec99ce4960fa12e37ebc472c1f420a98 220 Pfam PF13578 Methyltransferase domain 54 185 4.1E-13 T 12-10-2018 UA74_00720 ec99ce4960fa12e37ebc472c1f420a98 220 SUPERFAMILY SSF53335 38 207 6.66E-8 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_01920 e58b0b9c3839f9806237e44a788077d3 66 SUPERFAMILY SSF54285 1 66 5.67E-16 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp UA74_01920 e58b0b9c3839f9806237e44a788077d3 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 2.8E-19 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis UA74_01920 e58b0b9c3839f9806237e44a788077d3 66 Gene3D G3DSA:3.10.20.30 1 66 5.0E-21 T 12-10-2018 IPR012675 Beta-grasp domain superfamily UA74_01920 e58b0b9c3839f9806237e44a788077d3 66 Pfam PF02597 ThiS family 3 66 2.7E-14 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 UA74_05155 5306cf2ef35a9798e1563d46a06fad43 366 SUPERFAMILY SSF55909 16 366 2.68E-101 T 12-10-2018 UA74_05155 5306cf2ef35a9798e1563d46a06fad43 366 Gene3D G3DSA:3.75.10.10 16 366 4.5E-119 T 12-10-2018 UA74_20460 2f0270092656353ac641d8babed64d53 211 Gene3D G3DSA:3.40.50.720 1 195 4.0E-54 T 12-10-2018 UA74_20460 2f0270092656353ac641d8babed64d53 211 SUPERFAMILY SSF51735 4 193 3.19E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_20460 2f0270092656353ac641d8babed64d53 211 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 90 1.6E-17 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UA74_16925 5cd604d48d5a7166c3a263c1c497103c 138 SMART SM00418 37 115 1.4E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_16925 5cd604d48d5a7166c3a263c1c497103c 138 SUPERFAMILY SSF46785 31 117 3.92E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_16925 5cd604d48d5a7166c3a263c1c497103c 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 6.3E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_16925 5cd604d48d5a7166c3a263c1c497103c 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 6.3E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_16925 5cd604d48d5a7166c3a263c1c497103c 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 70 6.3E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_16925 5cd604d48d5a7166c3a263c1c497103c 138 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 6.3E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_16925 5cd604d48d5a7166c3a263c1c497103c 138 Pfam PF01022 Bacterial regulatory protein, arsR family 44 91 6.8E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_16925 5cd604d48d5a7166c3a263c1c497103c 138 Gene3D G3DSA:1.10.10.10 3 120 4.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08765 1bc42b8f5c1e354a041d5885e026bc0d 141 Gene3D G3DSA:1.10.10.10 1 135 3.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08765 1bc42b8f5c1e354a041d5885e026bc0d 141 SUPERFAMILY SSF46785 5 133 1.57E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_12470 ce72e3c626159bfc800de9a7ee26ea65 322 Gene3D G3DSA:3.40.50.720 121 266 9.1E-113 T 12-10-2018 UA74_12470 ce72e3c626159bfc800de9a7ee26ea65 322 SMART SM00829 10 320 5.1E-30 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_12470 ce72e3c626159bfc800de9a7ee26ea65 322 SUPERFAMILY SSF50129 1 142 1.11E-37 T 12-10-2018 IPR011032 GroES-like superfamily UA74_12470 ce72e3c626159bfc800de9a7ee26ea65 322 Pfam PF00107 Zinc-binding dehydrogenase 149 252 2.1E-27 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_12470 ce72e3c626159bfc800de9a7ee26ea65 322 Gene3D G3DSA:3.90.180.10 10 318 9.1E-113 T 12-10-2018 UA74_12470 ce72e3c626159bfc800de9a7ee26ea65 322 SUPERFAMILY SSF51735 111 263 6.88E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12470 ce72e3c626159bfc800de9a7ee26ea65 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 8.4E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_20825 a54a26f4325f919a4e3a288d18bcaf26 311 SUPERFAMILY SSF53850 94 296 3.08E-20 T 12-10-2018 UA74_20825 a54a26f4325f919a4e3a288d18bcaf26 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 7.4E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_20825 a54a26f4325f919a4e3a288d18bcaf26 311 Gene3D G3DSA:1.10.10.10 1 85 8.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20825 a54a26f4325f919a4e3a288d18bcaf26 311 SUPERFAMILY SSF46785 7 112 2.16E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20825 a54a26f4325f919a4e3a288d18bcaf26 311 Gene3D G3DSA:3.40.190.290 89 296 9.0E-77 T 12-10-2018 UA74_20825 a54a26f4325f919a4e3a288d18bcaf26 311 Pfam PF03466 LysR substrate binding domain 117 292 6.4E-15 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_20825 a54a26f4325f919a4e3a288d18bcaf26 311 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 7 295 6.0E-104 T 12-10-2018 IPR017685 HTH-type transcriptional regulator ArgP UA74_03360 2f64461db394a998b21ca577ef3727f3 187 Pfam PF07336 Putative stress-induced transcription regulator 20 141 2.2E-17 T 12-10-2018 IPR010852 Putative stress-induced transcription regulator UA74_03360 2f64461db394a998b21ca577ef3727f3 187 Pfam PF11706 CGNR zinc finger 145 186 2.9E-19 T 12-10-2018 IPR021005 Zinc finger, CGNR UA74_03360 2f64461db394a998b21ca577ef3727f3 187 Gene3D G3DSA:1.10.3300.10 29 187 5.2E-27 T 12-10-2018 IPR023286 ABATE domain superfamily UA74_03360 2f64461db394a998b21ca577ef3727f3 187 SUPERFAMILY SSF160904 15 186 1.01E-38 T 12-10-2018 UA74_16270 50300d2d85c9fb37f8c5f4d9feb2d571 355 Gene3D G3DSA:3.40.50.150 16 143 5.9E-20 T 12-10-2018 UA74_16270 50300d2d85c9fb37f8c5f4d9feb2d571 355 Gene3D G3DSA:3.40.50.150 148 345 6.4E-11 T 12-10-2018 UA74_16270 50300d2d85c9fb37f8c5f4d9feb2d571 355 SUPERFAMILY SSF53335 73 242 2.95E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_16270 50300d2d85c9fb37f8c5f4d9feb2d571 355 Pfam PF01555 DNA methylase 39 131 2.1E-14 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 UA74_16270 50300d2d85c9fb37f8c5f4d9feb2d571 355 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 93 111 1.7E-7 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UA74_16270 50300d2d85c9fb37f8c5f4d9feb2d571 355 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 116 136 1.7E-7 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UA74_24805 3a734a21a471106ff4f8c8d51a44d4dd 448 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 223 236 1.2E-12 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_24805 3a734a21a471106ff4f8c8d51a44d4dd 448 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 147 161 1.2E-12 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_24805 3a734a21a471106ff4f8c8d51a44d4dd 448 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 22 38 1.2E-12 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_24805 3a734a21a471106ff4f8c8d51a44d4dd 448 SUPERFAMILY SSF53335 23 437 1.31E-68 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_24805 3a734a21a471106ff4f8c8d51a44d4dd 448 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 109 121 - T 12-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 UA74_24805 3a734a21a471106ff4f8c8d51a44d4dd 448 Gene3D G3DSA:3.90.120.10 356 426 3.6E-12 T 12-10-2018 UA74_24805 3a734a21a471106ff4f8c8d51a44d4dd 448 Pfam PF00145 C-5 cytosine-specific DNA methylase 23 176 1.3E-25 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_24805 3a734a21a471106ff4f8c8d51a44d4dd 448 Pfam PF00145 C-5 cytosine-specific DNA methylase 210 432 1.4E-20 T 12-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UA74_13225 c7a30458e182a5c908a0f57eddfd63a7 468 SUPERFAMILY SSF81345 138 463 8.11E-78 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_13225 c7a30458e182a5c908a0f57eddfd63a7 468 Gene3D G3DSA:1.10.3470.10 136 466 2.8E-91 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_13225 c7a30458e182a5c908a0f57eddfd63a7 468 Pfam PF01032 FecCD transport family 147 462 5.6E-88 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_15410 6fb3a3a7e0d56489fff4d67828efb76e 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 426 445 4.0E-5 T 12-10-2018 UA74_15410 6fb3a3a7e0d56489fff4d67828efb76e 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 164 188 4.0E-5 T 12-10-2018 UA74_15410 6fb3a3a7e0d56489fff4d67828efb76e 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 125 4.0E-5 T 12-10-2018 UA74_15410 6fb3a3a7e0d56489fff4d67828efb76e 533 PRINTS PR01036 Tetracycline resistance protein TetB signature 43 67 4.0E-5 T 12-10-2018 UA74_15410 6fb3a3a7e0d56489fff4d67828efb76e 533 SUPERFAMILY SSF103473 27 525 1.96E-66 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_15410 6fb3a3a7e0d56489fff4d67828efb76e 533 Gene3D G3DSA:1.20.1720.10 39 248 2.4E-46 T 12-10-2018 UA74_15410 6fb3a3a7e0d56489fff4d67828efb76e 533 Pfam PF07690 Major Facilitator Superfamily 44 435 8.4E-50 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_15410 6fb3a3a7e0d56489fff4d67828efb76e 533 Gene3D G3DSA:1.20.1250.20 291 526 6.7E-19 T 12-10-2018 UA74_27790 ffd981dfeac0036bc09fe00c3cdbd69f 547 Gene3D G3DSA:1.10.510.10 91 272 7.8E-44 T 12-10-2018 UA74_27790 ffd981dfeac0036bc09fe00c3cdbd69f 547 Gene3D G3DSA:3.30.200.20 2 90 3.7E-27 T 12-10-2018 UA74_27790 ffd981dfeac0036bc09fe00c3cdbd69f 547 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UA74_27790 ffd981dfeac0036bc09fe00c3cdbd69f 547 SMART SM00220 12 270 8.7E-64 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_27790 ffd981dfeac0036bc09fe00c3cdbd69f 547 Pfam PF00069 Protein kinase domain 12 264 8.0E-49 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_27790 ffd981dfeac0036bc09fe00c3cdbd69f 547 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UA74_27790 ffd981dfeac0036bc09fe00c3cdbd69f 547 SUPERFAMILY SSF56112 5 268 2.43E-71 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_20335 99dab624413a2b4544b7c2532d7bae29 336 Gene3D G3DSA:3.40.50.1980 42 156 2.1E-22 T 12-10-2018 UA74_20335 99dab624413a2b4544b7c2532d7bae29 336 Pfam PF01497 Periplasmic binding protein 66 297 8.2E-24 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_20335 99dab624413a2b4544b7c2532d7bae29 336 SUPERFAMILY SSF53807 48 325 1.26E-52 T 12-10-2018 UA74_20335 99dab624413a2b4544b7c2532d7bae29 336 Gene3D G3DSA:3.40.50.1980 158 332 1.0E-42 T 12-10-2018 UA74_28930 719fbb09dfe111ea6255e698bc4be872 314 Pfam PF12697 Alpha/beta hydrolase family 29 297 2.8E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_28930 719fbb09dfe111ea6255e698bc4be872 314 SUPERFAMILY SSF53474 8 304 4.73E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_28930 719fbb09dfe111ea6255e698bc4be872 314 Gene3D G3DSA:3.40.50.1820 4 304 3.2E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05135 10fab9a81f31992d7566f8b69c5e5712 577 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_05135 10fab9a81f31992d7566f8b69c5e5712 577 SUPERFAMILY SSF90123 19 331 1.03E-46 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_05135 10fab9a81f31992d7566f8b69c5e5712 577 Gene3D G3DSA:1.20.1560.10 8 332 2.3E-46 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_05135 10fab9a81f31992d7566f8b69c5e5712 577 Gene3D G3DSA:3.40.50.300 337 575 9.5E-38 T 12-10-2018 UA74_05135 10fab9a81f31992d7566f8b69c5e5712 577 Pfam PF00664 ABC transporter transmembrane region 36 301 4.3E-25 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_05135 10fab9a81f31992d7566f8b69c5e5712 577 Pfam PF00005 ABC transporter 382 496 3.5E-7 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_05135 10fab9a81f31992d7566f8b69c5e5712 577 SUPERFAMILY SSF52540 354 568 2.08E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16595 9cefc596936a5aaa488cc0a5ee24f1bd 502 Pfam PF07690 Major Facilitator Superfamily 15 408 2.4E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_16595 9cefc596936a5aaa488cc0a5ee24f1bd 502 Gene3D G3DSA:1.20.1250.20 257 464 1.4E-17 T 12-10-2018 UA74_16595 9cefc596936a5aaa488cc0a5ee24f1bd 502 Gene3D G3DSA:1.20.1720.10 11 217 6.4E-46 T 12-10-2018 UA74_16595 9cefc596936a5aaa488cc0a5ee24f1bd 502 SUPERFAMILY SSF103473 6 460 2.62E-64 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_10100 d2c9200ae9ca0e6b3e3649e7ce645121 532 Gene3D G3DSA:1.20.1250.20 17 216 1.5E-42 T 12-10-2018 UA74_10100 d2c9200ae9ca0e6b3e3649e7ce645121 532 SUPERFAMILY SSF103473 18 454 2.09E-65 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_10100 d2c9200ae9ca0e6b3e3649e7ce645121 532 Pfam PF07690 Major Facilitator Superfamily 28 289 2.8E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_10100 d2c9200ae9ca0e6b3e3649e7ce645121 532 Gene3D G3DSA:1.20.1250.20 273 458 3.7E-21 T 12-10-2018 UA74_26460 174f5cef3f936ef8460c815f0d355765 261 Gene3D G3DSA:3.90.1680.10 1 243 7.6E-64 T 12-10-2018 IPR036590 SOS response associated peptidase-like UA74_26460 174f5cef3f936ef8460c815f0d355765 261 Pfam PF02586 SOS response associated peptidase (SRAP) 1 232 6.8E-62 T 12-10-2018 IPR003738 SOS response associated peptidase (SRAP) UA74_26460 174f5cef3f936ef8460c815f0d355765 261 SUPERFAMILY SSF143081 2 241 5.89E-63 T 12-10-2018 IPR036590 SOS response associated peptidase-like UA74_19375 0bb91ca7a1ea559db3c636aad64537d7 346 Pfam PF01497 Periplasmic binding protein 83 319 2.0E-15 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_19375 0bb91ca7a1ea559db3c636aad64537d7 346 Gene3D G3DSA:3.40.50.1980 52 161 3.5E-12 T 12-10-2018 UA74_19375 0bb91ca7a1ea559db3c636aad64537d7 346 SUPERFAMILY SSF53807 60 338 4.71E-36 T 12-10-2018 UA74_19375 0bb91ca7a1ea559db3c636aad64537d7 346 Gene3D G3DSA:3.40.50.1980 167 344 6.7E-29 T 12-10-2018 UA74_19375 0bb91ca7a1ea559db3c636aad64537d7 346 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 21 47 6.8E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal UA74_12915 cd11987c14af532365ed11dfe1a3bea0 329 PIRSF PIRSF016838 1 320 7.4E-119 T 12-10-2018 IPR028349 Protein PafC UA74_12915 cd11987c14af532365ed11dfe1a3bea0 329 Pfam PF13280 WYL domain 149 312 1.1E-33 T 12-10-2018 IPR026881 WYL domain UA74_18580 c970c6a3139758a1ad6c376ae4bcff09 160 Gene3D G3DSA:3.10.129.10 1 148 5.1E-36 T 12-10-2018 UA74_18580 c970c6a3139758a1ad6c376ae4bcff09 160 SUPERFAMILY SSF54637 7 141 2.84E-23 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_18580 c970c6a3139758a1ad6c376ae4bcff09 160 Pfam PF13279 Thioesterase-like superfamily 13 137 2.9E-8 T 12-10-2018 UA74_05670 936bda615867f61368359e827669c4c8 500 Gene3D G3DSA:3.90.79.40 338 496 1.2E-58 T 12-10-2018 IPR038153 NDP-hexose 2,3-dehydratase-like superfamily KEGG: 00523+4.2.1.159 UA74_05670 936bda615867f61368359e827669c4c8 500 Gene3D G3DSA:3.90.79.40 80 243 9.3E-60 T 12-10-2018 IPR038153 NDP-hexose 2,3-dehydratase-like superfamily KEGG: 00523+4.2.1.159 UA74_05670 936bda615867f61368359e827669c4c8 500 Pfam PF03559 NDP-hexose 2,3-dehydratase 285 486 4.7E-75 T 12-10-2018 IPR005212 NDP-hexose 2,3-dehydratase KEGG: 00523+4.2.1.159 UA74_05670 936bda615867f61368359e827669c4c8 500 Pfam PF03559 NDP-hexose 2,3-dehydratase 29 236 2.1E-80 T 12-10-2018 IPR005212 NDP-hexose 2,3-dehydratase KEGG: 00523+4.2.1.159 UA74_10885 304179eb08565b00662dedc8234d914d 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_10885 304179eb08565b00662dedc8234d914d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10885 304179eb08565b00662dedc8234d914d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10885 304179eb08565b00662dedc8234d914d 245 Gene3D G3DSA:3.40.50.720 2 245 4.9E-79 T 12-10-2018 UA74_10885 304179eb08565b00662dedc8234d914d 245 SUPERFAMILY SSF51735 7 244 4.53E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_10885 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10885 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10885 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10885 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10885 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10885 304179eb08565b00662dedc8234d914d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10885 304179eb08565b00662dedc8234d914d 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 3.2E-62 T 12-10-2018 UA74_10885 304179eb08565b00662dedc8234d914d 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 190 7.9E-5 T 12-10-2018 UA74_01785 03a7c22b254140f2972239e5bdd92b6a 409 Pfam PF13416 Bacterial extracellular solute-binding protein 45 346 2.2E-42 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_01785 03a7c22b254140f2972239e5bdd92b6a 409 SUPERFAMILY SSF53850 28 395 3.26E-79 T 12-10-2018 UA74_01785 03a7c22b254140f2972239e5bdd92b6a 409 Gene3D G3DSA:3.40.190.10 43 361 1.9E-95 T 12-10-2018 UA74_01785 03a7c22b254140f2972239e5bdd92b6a 409 Gene3D G3DSA:3.40.190.10 138 390 1.9E-95 T 12-10-2018 UA74_26620 e83e58e621ec9021567ae1c1e8ecc0a6 179 Gene3D G3DSA:3.90.79.10 4 177 2.8E-34 T 12-10-2018 UA74_26620 e83e58e621ec9021567ae1c1e8ecc0a6 179 Pfam PF00293 NUDIX domain 47 160 5.7E-11 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_26620 e83e58e621ec9021567ae1c1e8ecc0a6 179 SUPERFAMILY SSF55811 29 168 7.72E-20 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_08265 8668d0deb82288e805270feb289db516 278 SUPERFAMILY SSF52266 10 238 1.67E-11 T 12-10-2018 UA74_08265 8668d0deb82288e805270feb289db516 278 Gene3D G3DSA:3.40.50.1110 10 239 2.8E-6 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_07045 96dcba6d5ce5bc3bacbda0e66555753d 180 Gene3D G3DSA:1.20.5.620 76 136 2.3E-8 T 12-10-2018 UA74_07045 96dcba6d5ce5bc3bacbda0e66555753d 180 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 25 171 2.6E-30 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 UA74_07045 96dcba6d5ce5bc3bacbda0e66555753d 180 Hamap MF_01398 ATP synthase subunit b [atpF]. 15 152 13.273 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 UA74_07045 96dcba6d5ce5bc3bacbda0e66555753d 180 SUPERFAMILY SSF81573 77 135 9.81E-14 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily UA74_07045 96dcba6d5ce5bc3bacbda0e66555753d 180 Pfam PF00430 ATP synthase B/B' CF(0) 21 149 2.5E-30 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 UA74_23490 de87d6ff92821e30efe3d52ef7150333 190 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 13 175 4.4E-47 T 12-10-2018 IPR006286 Deglycase PfpI UA74_23490 de87d6ff92821e30efe3d52ef7150333 190 Pfam PF01965 DJ-1/PfpI family 9 176 5.5E-53 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UA74_23490 de87d6ff92821e30efe3d52ef7150333 190 SUPERFAMILY SSF52317 9 178 2.01E-44 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_23490 de87d6ff92821e30efe3d52ef7150333 190 Gene3D G3DSA:3.40.50.880 1 187 2.3E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_16880 f6e65c009f82570bd52f8dc4728b0d18 483 Gene3D G3DSA:1.20.1250.20 258 471 2.9E-15 T 12-10-2018 UA74_16880 f6e65c009f82570bd52f8dc4728b0d18 483 SUPERFAMILY SSF103473 8 468 2.62E-57 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_16880 f6e65c009f82570bd52f8dc4728b0d18 483 Pfam PF07690 Major Facilitator Superfamily 15 407 9.0E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_16880 f6e65c009f82570bd52f8dc4728b0d18 483 Gene3D G3DSA:1.20.1720.10 10 224 8.1E-41 T 12-10-2018 UA74_20120 c0363db57d1d0d1e31eede551d62767c 562 Gene3D G3DSA:3.10.105.10 303 532 4.3E-110 T 12-10-2018 UA74_20120 c0363db57d1d0d1e31eede551d62767c 562 Gene3D G3DSA:3.90.76.10 79 227 4.3E-110 T 12-10-2018 UA74_20120 c0363db57d1d0d1e31eede551d62767c 562 SUPERFAMILY SSF53850 67 557 9.77E-115 T 12-10-2018 UA74_20120 c0363db57d1d0d1e31eede551d62767c 562 PIRSF PIRSF002741 24 557 3.0E-87 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_20120 c0363db57d1d0d1e31eede551d62767c 562 Gene3D G3DSA:3.40.190.10 228 541 4.3E-110 T 12-10-2018 UA74_20120 c0363db57d1d0d1e31eede551d62767c 562 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 112 476 4.9E-68 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_14135 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 186 201 5.4E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14135 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 208 236 5.4E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14135 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 261 281 5.4E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14135 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 320 336 5.4E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14135 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 340 354 5.4E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14135 caf32a63c4e85200f83eb79653322177 385 PRINTS PR00143 Citrate synthase signature 137 150 5.4E-35 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14135 caf32a63c4e85200f83eb79653322177 385 Pfam PF00285 Citrate synthase, C-terminal domain 14 370 9.4E-106 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 UA74_14135 caf32a63c4e85200f83eb79653322177 385 ProSitePatterns PS00480 Citrate synthase signature. 268 280 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_14135 caf32a63c4e85200f83eb79653322177 385 Gene3D G3DSA:1.10.230.10 234 334 2.9E-104 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain UA74_14135 caf32a63c4e85200f83eb79653322177 385 PIRSF PIRSF001369 6 384 8.4E-102 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type UA74_14135 caf32a63c4e85200f83eb79653322177 385 SUPERFAMILY SSF48256 10 378 7.98E-109 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 UA74_14135 caf32a63c4e85200f83eb79653322177 385 Gene3D G3DSA:1.10.580.10 25 360 2.9E-104 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UA74_26010 694a7f30ae4fbb4ca1d187d9f2147993 282 SUPERFAMILY SSF51735 2 261 1.5E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_26010 694a7f30ae4fbb4ca1d187d9f2147993 282 Gene3D G3DSA:3.40.50.720 3 265 1.6E-68 T 12-10-2018 UA74_26010 694a7f30ae4fbb4ca1d187d9f2147993 282 Pfam PF13460 NAD(P)H-binding 6 181 2.9E-14 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_26010 694a7f30ae4fbb4ca1d187d9f2147993 282 Gene3D G3DSA:3.90.25.10 138 266 1.6E-68 T 12-10-2018 UA74_29575 903b4df8df461ce41a364f24ca6e5856 325 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 131 219 2.7E-10 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_29575 903b4df8df461ce41a364f24ca6e5856 325 SUPERFAMILY SSF50475 125 259 9.72E-14 T 12-10-2018 UA74_29575 903b4df8df461ce41a364f24ca6e5856 325 Gene3D G3DSA:2.30.110.10 125 256 4.1E-27 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_27630 2c731c96e8fd19f08dc7a48f27356c50 1191 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 368 783 4.2E-140 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_27630 2c731c96e8fd19f08dc7a48f27356c50 1191 Pfam PF14579 Helix-hairpin-helix motif 856 1025 7.2E-22 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_27630 2c731c96e8fd19f08dc7a48f27356c50 1191 Pfam PF02811 PHP domain 78 249 3.6E-32 T 12-10-2018 IPR004013 PHP domain GO:0003824 UA74_27630 2c731c96e8fd19f08dc7a48f27356c50 1191 SMART SM00481 77 144 4.6E-26 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal UA74_27630 2c731c96e8fd19f08dc7a48f27356c50 1191 Gene3D G3DSA:3.20.20.140 43 346 9.4E-83 T 12-10-2018 UA74_27630 2c731c96e8fd19f08dc7a48f27356c50 1191 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 77 874 3.1E-189 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_27630 2c731c96e8fd19f08dc7a48f27356c50 1191 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 76 1191 12.703 T 12-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_27630 2c731c96e8fd19f08dc7a48f27356c50 1191 SUPERFAMILY SSF89550 77 284 8.24E-22 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UA74_00265 2df3388eb9cf1fdeda2e4ec94472d39f 330 Gene3D G3DSA:3.40.190.120 154 264 1.5E-92 T 12-10-2018 UA74_00265 2df3388eb9cf1fdeda2e4ec94472d39f 330 Gene3D G3DSA:3.40.190.10 54 324 1.5E-92 T 12-10-2018 UA74_00265 2df3388eb9cf1fdeda2e4ec94472d39f 330 SUPERFAMILY SSF53850 54 325 2.14E-59 T 12-10-2018 UA74_00265 2df3388eb9cf1fdeda2e4ec94472d39f 330 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 54 321 1.6E-59 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 UA74_03275 41fed1b468e58898febb256d0f3dee21 298 Pfam PF00483 Nucleotidyl transferase 10 272 8.5E-28 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_03275 41fed1b468e58898febb256d0f3dee21 298 SUPERFAMILY SSF53448 9 288 1.26E-56 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_03275 41fed1b468e58898febb256d0f3dee21 298 Gene3D G3DSA:3.90.550.10 2 297 4.7E-83 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_22445 7610d5efc4d0e030c952c16f900ec4ad 256 Gene3D G3DSA:1.10.1780.10 57 204 1.1E-38 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UA74_22445 7610d5efc4d0e030c952c16f900ec4ad 256 SUPERFAMILY SSF81923 60 196 2.35E-23 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UA74_22445 7610d5efc4d0e030c952c16f900ec4ad 256 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 74 122 1.7E-6 T 12-10-2018 IPR004176 Clp, N-terminal UA74_22445 7610d5efc4d0e030c952c16f900ec4ad 256 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 151 200 2.0E-14 T 12-10-2018 IPR004176 Clp, N-terminal UA74_12955 53afa6dde4446212b239e5493572f103 320 SMART SM00279 195 230 6.3E-10 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 UA74_12955 53afa6dde4446212b239e5493572f103 320 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 197 284 2.2E-16 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 UA74_12955 53afa6dde4446212b239e5493572f103 320 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 188 5.3E-45 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 UA74_12955 53afa6dde4446212b239e5493572f103 320 Gene3D G3DSA:1.10.150.20 196 272 5.5E-60 T 12-10-2018 UA74_12955 53afa6dde4446212b239e5493572f103 320 Gene3D G3DSA:3.40.50.1010 5 298 5.5E-60 T 12-10-2018 UA74_12955 53afa6dde4446212b239e5493572f103 320 SUPERFAMILY SSF47807 198 310 6.13E-19 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily UA74_12955 53afa6dde4446212b239e5493572f103 320 SMART SM00475 3 287 4.8E-76 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 UA74_12955 53afa6dde4446212b239e5493572f103 320 SUPERFAMILY SSF88723 4 168 8.63E-36 T 12-10-2018 IPR029060 PIN-like domain superfamily UA74_13120 41a51cedfece9949772f04ff9282fd6a 347 Gene3D G3DSA:1.10.10.10 1 89 5.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13120 41a51cedfece9949772f04ff9282fd6a 347 SUPERFAMILY SSF53335 95 327 4.55E-52 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_13120 41a51cedfece9949772f04ff9282fd6a 347 Gene3D G3DSA:3.40.50.150 93 341 1.3E-73 T 12-10-2018 UA74_13120 41a51cedfece9949772f04ff9282fd6a 347 SUPERFAMILY SSF46785 12 92 1.94E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_13120 41a51cedfece9949772f04ff9282fd6a 347 Pfam PF16864 Dimerisation domain 16 76 7.0E-9 T 12-10-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain UA74_13120 41a51cedfece9949772f04ff9282fd6a 347 PIRSF PIRSF005739 1 335 6.2E-58 T 12-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_13120 41a51cedfece9949772f04ff9282fd6a 347 Pfam PF00891 O-methyltransferase 104 326 1.4E-50 T 12-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_18830 bd16f509a84994021b42cd37699f868f 370 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 118 3.1E-19 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_18830 bd16f509a84994021b42cd37699f868f 370 SUPERFAMILY SSF55347 136 276 1.64E-26 T 12-10-2018 UA74_18830 bd16f509a84994021b42cd37699f868f 370 SUPERFAMILY SSF51735 4 161 3.49E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18830 bd16f509a84994021b42cd37699f868f 370 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 245 3.0E-12 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UA74_18830 bd16f509a84994021b42cd37699f868f 370 Gene3D G3DSA:3.40.50.720 10 318 3.9E-81 T 12-10-2018 UA74_18830 bd16f509a84994021b42cd37699f868f 370 Gene3D G3DSA:3.30.360.10 133 340 3.9E-81 T 12-10-2018 UA74_02810 7094dc15d59ab0839faecf25bf14c3ce 185 SUPERFAMILY SSF54637 7 153 4.39E-41 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_02810 7094dc15d59ab0839faecf25bf14c3ce 185 Hamap MF_00799 UPF0336 protein . 1 148 32.47 T 12-10-2018 IPR016709 Uncharacterised protein family UPF0336 UA74_02810 7094dc15d59ab0839faecf25bf14c3ce 185 Pfam PF13452 N-terminal half of MaoC dehydratase 6 135 1.2E-31 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 UA74_02810 7094dc15d59ab0839faecf25bf14c3ce 185 Gene3D G3DSA:3.10.129.10 1 154 3.6E-47 T 12-10-2018 UA74_06225 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 Gene3D G3DSA:3.40.50.1100 40 159 6.6E-102 T 12-10-2018 UA74_06225 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 SUPERFAMILY SSF53686 2 298 1.11E-85 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_06225 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 287 4.5E-66 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_06225 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 Gene3D G3DSA:3.40.50.1100 8 295 6.6E-102 T 12-10-2018 UA74_06225 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 299 1.0E-109 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 UA74_06225 2da3ec0ef57f9b19ec4b3d7ba6ab5701 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 PIRSF PIRSF000097 1 279 7.0E-78 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 122 139 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 Gene3D G3DSA:3.20.20.100 1 279 4.8E-100 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 Pfam PF00248 Aldo/keto reductase family 20 266 1.1E-43 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 122 139 3.1E-42 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 202 226 3.1E-42 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 89 107 3.1E-42 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 156 185 3.1E-42 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 PRINTS PR00069 Aldo-keto reductase signature 33 57 3.1E-42 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 SUPERFAMILY SSF51430 3 272 4.98E-85 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_07810 537d8d7af448e782059fcfecc5ba78d0 291 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 37 54 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UA74_23315 7df59bacfd821fd613bf303a4986ba1c 458 Pfam PF13535 ATP-grasp domain 132 291 1.9E-8 T 12-10-2018 UA74_23315 7df59bacfd821fd613bf303a4986ba1c 458 Gene3D G3DSA:3.30.470.20 92 428 7.8E-31 T 12-10-2018 UA74_23315 7df59bacfd821fd613bf303a4986ba1c 458 SUPERFAMILY SSF56059 116 334 2.7E-29 T 12-10-2018 UA74_17680 fdd697dee94b8289fb4be4b9105481c7 253 Gene3D G3DSA:3.40.50.300 7 236 1.3E-50 T 12-10-2018 UA74_17680 fdd697dee94b8289fb4be4b9105481c7 253 SUPERFAMILY SSF52540 12 228 1.05E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_17680 fdd697dee94b8289fb4be4b9105481c7 253 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 12 228 6.5E-53 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 UA74_12225 abcce6ee06e2b7fd6614dec3361947fd 212 SUPERFAMILY SSF52540 5 188 1.49E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12225 abcce6ee06e2b7fd6614dec3361947fd 212 Hamap MF_00328 Guanylate kinase [gmk]. 6 191 35.529 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 UA74_12225 abcce6ee06e2b7fd6614dec3361947fd 212 Gene3D G3DSA:3.30.63.10 39 102 2.9E-62 T 12-10-2018 UA74_12225 abcce6ee06e2b7fd6614dec3361947fd 212 ProSitePatterns PS00856 Guanylate kinase-like signature. 42 59 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 UA74_12225 abcce6ee06e2b7fd6614dec3361947fd 212 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 8 187 1.0E-63 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 UA74_12225 abcce6ee06e2b7fd6614dec3361947fd 212 SMART SM00072 7 191 1.2E-60 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit UA74_12225 abcce6ee06e2b7fd6614dec3361947fd 212 Gene3D G3DSA:3.40.50.300 9 183 2.9E-62 T 12-10-2018 UA74_12225 abcce6ee06e2b7fd6614dec3361947fd 212 Pfam PF00625 Guanylate kinase 8 187 2.0E-40 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit UA74_25750 e04cc3c318f657c88fa93af5feaaffd5 77 SUPERFAMILY SSF54909 2 76 3.75E-14 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_25750 e04cc3c318f657c88fa93af5feaaffd5 77 Gene3D G3DSA:3.30.70.920 2 73 2.7E-19 T 12-10-2018 UA74_25750 e04cc3c318f657c88fa93af5feaaffd5 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 75 1.6E-12 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_04395 c0eeb725065d2b5401e4a94f4b759779 332 Gene3D G3DSA:3.40.50.10320 11 303 4.1E-91 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_04395 c0eeb725065d2b5401e4a94f4b759779 332 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 17 279 4.0E-87 T 12-10-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 UA74_04395 c0eeb725065d2b5401e4a94f4b759779 332 Pfam PF02585 GlcNAc-PI de-N-acetylase 17 174 1.3E-24 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_04395 c0eeb725065d2b5401e4a94f4b759779 332 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 16 301 35.548 T 12-10-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 UA74_04395 c0eeb725065d2b5401e4a94f4b759779 332 SUPERFAMILY SSF102588 15 281 2.09E-57 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_28965 c00ca9483bfc019c0580aafce07a20dc 389 Gene3D G3DSA:1.25.40.10 168 380 1.9E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_28965 c00ca9483bfc019c0580aafce07a20dc 389 SUPERFAMILY SSF48452 165 366 2.1E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_10780 c6ce4468335cef3ab29aeabed138b79e 413 SUPERFAMILY SSF55811 246 383 6.91E-19 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_10780 c6ce4468335cef3ab29aeabed138b79e 413 SUPERFAMILY SSF140478 169 240 6.8E-5 T 12-10-2018 IPR023353 LemA-like domain superfamily UA74_10780 c6ce4468335cef3ab29aeabed138b79e 413 Pfam PF00293 NUDIX domain 256 383 8.6E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_10780 c6ce4468335cef3ab29aeabed138b79e 413 ProSitePatterns PS00893 Nudix box signature. 292 313 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_10780 c6ce4468335cef3ab29aeabed138b79e 413 Gene3D G3DSA:3.90.79.10 243 389 5.7E-23 T 12-10-2018 UA74_25820 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 Gene3D G3DSA:3.90.550.10 3 177 4.8E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_25820 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 Pfam PF01983 Guanylyl transferase CofC like 7 207 1.7E-8 T 12-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 UA74_25820 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 5 212 21.387 T 12-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 UA74_25820 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 SUPERFAMILY SSF53448 17 209 6.19E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_25820 dc5ab04346e1ab7c4a49fc2e0bbc98f0 220 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 7 205 1.7E-40 T 12-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 UA74_22450 6816d7de708441a60e3ccf92a1842ba4 274 Gene3D G3DSA:1.10.1660.10 1 118 4.0E-23 T 12-10-2018 UA74_22450 6816d7de708441a60e3ccf92a1842ba4 274 SMART SM00871 119 271 6.9E-13 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding UA74_22450 6816d7de708441a60e3ccf92a1842ba4 274 SUPERFAMILY SSF55136 121 270 1.4E-18 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UA74_22450 6816d7de708441a60e3ccf92a1842ba4 274 Pfam PF13411 MerR HTH family regulatory protein 2 71 1.6E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_22450 6816d7de708441a60e3ccf92a1842ba4 274 SMART SM00422 2 72 5.1E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_22450 6816d7de708441a60e3ccf92a1842ba4 274 Pfam PF06445 GyrI-like small molecule binding domain 123 267 6.7E-9 T 12-10-2018 IPR029442 GyrI-like small molecule binding domain UA74_22450 6816d7de708441a60e3ccf92a1842ba4 274 SUPERFAMILY SSF46955 2 111 1.98E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_22450 6816d7de708441a60e3ccf92a1842ba4 274 Gene3D G3DSA:3.20.80.10 119 271 1.4E-18 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UA74_02980 366141442d3b8147e6348bb680f19a9a 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.223 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 7.5E-46 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.6E-53 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 SUPERFAMILY SSF54686 2 136 1.44E-53 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.3E-36 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.3E-36 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.3E-36 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.3E-36 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02980 366141442d3b8147e6348bb680f19a9a 139 Gene3D G3DSA:3.90.1170.10 2 138 8.4E-49 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 UA74_05410 62e3f6268a0c0dd65a526d6a3d772cfa 211 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 53 205 6.6E-8 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase UA74_05410 62e3f6268a0c0dd65a526d6a3d772cfa 211 Gene3D G3DSA:3.30.530.20 50 211 1.0E-9 T 12-10-2018 IPR023393 START-like domain superfamily UA74_05410 62e3f6268a0c0dd65a526d6a3d772cfa 211 SUPERFAMILY SSF55961 53 205 1.2E-13 T 12-10-2018 UA74_13795 37fc8fd889e00039c8389e24a33deac6 338 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 6 323 23.881 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_13795 37fc8fd889e00039c8389e24a33deac6 338 Gene3D G3DSA:3.100.10.20 6 82 5.1E-11 T 12-10-2018 UA74_13795 37fc8fd889e00039c8389e24a33deac6 338 Pfam PF01867 CRISPR associated protein Cas1 8 292 2.0E-83 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_13795 37fc8fd889e00039c8389e24a33deac6 338 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 332 4.4E-74 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_13795 37fc8fd889e00039c8389e24a33deac6 338 Gene3D G3DSA:1.20.120.920 89 337 5.6E-66 T 12-10-2018 UA74_19155 b1a5c2679132d5e4ed6182f24d1c2778 510 Pfam PF00361 Proton-conducting membrane transporter 126 413 8.5E-48 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_19155 b1a5c2679132d5e4ed6182f24d1c2778 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 369 395 2.9E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_19155 b1a5c2679132d5e4ed6182f24d1c2778 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 161 185 2.9E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_19155 b1a5c2679132d5e4ed6182f24d1c2778 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 131 150 2.9E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_19155 b1a5c2679132d5e4ed6182f24d1c2778 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 317 336 2.9E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_22655 63ec771509f0150635e11b6628c6623f 320 Gene3D G3DSA:1.10.3720.10 87 295 1.3E-15 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22655 63ec771509f0150635e11b6628c6623f 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 290 5.3E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_22655 63ec771509f0150635e11b6628c6623f 320 SUPERFAMILY SSF161098 94 280 9.27E-22 T 12-10-2018 IPR035906 MetI-like superfamily UA74_21275 de8e7c5070699d2e4c1bc470a94cf811 766 SMART SM00947 578 750 5.8E-53 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_21275 de8e7c5070699d2e4c1bc470a94cf811 766 Pfam PF00916 Sulfate permease family 32 382 1.4E-69 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 UA74_21275 de8e7c5070699d2e4c1bc470a94cf811 766 Gene3D G3DSA:3.40.1050.10 540 758 1.4E-59 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UA74_21275 de8e7c5070699d2e4c1bc470a94cf811 766 Pfam PF00484 Carbonic anhydrase 586 745 5.1E-45 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_21275 de8e7c5070699d2e4c1bc470a94cf811 766 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 634 654 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_21275 de8e7c5070699d2e4c1bc470a94cf811 766 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 590 597 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_21275 de8e7c5070699d2e4c1bc470a94cf811 766 SUPERFAMILY SSF53056 521 752 1.7E-50 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UA74_17100 f87848bd11283bcf24e0be014c66e413 482 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_17100 f87848bd11283bcf24e0be014c66e413 482 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 473 78.926 T 12-10-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_17100 f87848bd11283bcf24e0be014c66e413 482 Gene3D G3DSA:1.10.287.400 377 438 2.1E-27 T 12-10-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_17100 f87848bd11283bcf24e0be014c66e413 482 SUPERFAMILY SSF69864 190 435 9.03E-75 T 12-10-2018 UA74_17100 f87848bd11283bcf24e0be014c66e413 482 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 4.5E-137 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_17100 f87848bd11283bcf24e0be014c66e413 482 Gene3D G3DSA:3.40.50.620 14 191 8.9E-113 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_17100 f87848bd11283bcf24e0be014c66e413 482 Gene3D G3DSA:3.90.1260.10 74 367 8.9E-113 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_17100 f87848bd11283bcf24e0be014c66e413 482 Pfam PF00764 Arginosuccinate synthase 16 404 3.2E-56 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_17100 f87848bd11283bcf24e0be014c66e413 482 SUPERFAMILY SSF52402 4 185 5.5E-31 T 12-10-2018 UA74_17100 f87848bd11283bcf24e0be014c66e413 482 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 SUPERFAMILY SSF52540 5 203 1.46E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 Pfam PF00005 ABC transporter 303 436 2.5E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 SMART SM00382 29 199 1.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 SMART SM00382 311 480 1.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 Gene3D G3DSA:3.40.50.300 268 512 1.6E-60 T 12-10-2018 UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 Gene3D G3DSA:3.40.50.300 2 235 5.4E-59 T 12-10-2018 UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 SUPERFAMILY SSF52540 271 484 1.73E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 Pfam PF16326 ABC transporter C-terminal domain 540 598 7.1E-8 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 UA74_03585 9b9f033b86f3bc4e2eff79068658e2eb 606 Pfam PF00005 ABC transporter 20 155 4.6E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_01525 c3692f6cbb222007e9d01c2d88501f0a 289 Pfam PF13560 Helix-turn-helix domain 12 72 6.4E-12 T 12-10-2018 UA74_01525 c3692f6cbb222007e9d01c2d88501f0a 289 SMART SM00530 16 71 7.0E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_01525 c3692f6cbb222007e9d01c2d88501f0a 289 SUPERFAMILY SSF47413 10 71 8.45E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_01525 c3692f6cbb222007e9d01c2d88501f0a 289 Gene3D G3DSA:1.10.260.40 5 69 8.4E-13 T 12-10-2018 UA74_29080 9bfc62bfee606aa72006b0c80456a053 677 Gene3D G3DSA:3.30.70.2390 521 602 5.2E-7 T 12-10-2018 UA74_29080 9bfc62bfee606aa72006b0c80456a053 677 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 522 605 5.5E-15 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain UA74_29080 9bfc62bfee606aa72006b0c80456a053 677 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 232 396 5.5E-36 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_29080 9bfc62bfee606aa72006b0c80456a053 677 Gene3D G3DSA:1.10.260.150 191 494 1.9E-60 T 12-10-2018 UA74_29080 9bfc62bfee606aa72006b0c80456a053 677 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 231 396 4.6E-44 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_28250 f09402002a69d7a515c550519b776285 461 PIRSF PIRSF006060 10 450 4.1E-70 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UA74_28250 f09402002a69d7a515c550519b776285 461 Gene3D G3DSA:1.20.1740.10 21 453 6.7E-77 T 12-10-2018 UA74_28250 f09402002a69d7a515c550519b776285 461 Pfam PF13520 Amino acid permease 32 413 3.5E-38 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UA74_01380 d4d45a1bc02f4d90d8185e43879f5745 277 Gene3D G3DSA:3.40.50.1000 18 227 2.1E-66 T 12-10-2018 IPR023214 HAD superfamily UA74_01380 d4d45a1bc02f4d90d8185e43879f5745 277 Pfam PF12710 haloacid dehalogenase-like hydrolase 18 202 1.3E-32 T 12-10-2018 UA74_01380 d4d45a1bc02f4d90d8185e43879f5745 277 SUPERFAMILY SSF56784 15 227 2.34E-29 T 12-10-2018 IPR036412 HAD-like superfamily UA74_01380 d4d45a1bc02f4d90d8185e43879f5745 277 Gene3D G3DSA:1.20.1440.100 29 103 2.1E-66 T 12-10-2018 UA74_01380 d4d45a1bc02f4d90d8185e43879f5745 277 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 17 204 1.9E-21 T 12-10-2018 UA74_01380 d4d45a1bc02f4d90d8185e43879f5745 277 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 17 215 1.5E-63 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like UA74_11665 69be96953ecacb51f281a769d3dcf821 944 Gene3D G3DSA:1.25.40.10 621 781 1.4E-95 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11665 69be96953ecacb51f281a769d3dcf821 944 SUPERFAMILY SSF56112 337 613 2.0E-47 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_11665 69be96953ecacb51f281a769d3dcf821 944 Gene3D G3DSA:1.10.510.10 435 603 9.0E-104 T 12-10-2018 UA74_11665 69be96953ecacb51f281a769d3dcf821 944 Gene3D G3DSA:1.25.40.10 630 939 1.4E-95 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_11665 69be96953ecacb51f281a769d3dcf821 944 Pfam PF16918 Protein kinase G tetratricopeptide repeat 618 942 1.8E-88 T 12-10-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 UA74_11665 69be96953ecacb51f281a769d3dcf821 944 SMART SM00220 347 602 3.7E-26 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_11665 69be96953ecacb51f281a769d3dcf821 944 Pfam PF16919 Protein kinase G rubredoxin domain 225 346 8.8E-36 T 12-10-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 UA74_11665 69be96953ecacb51f281a769d3dcf821 944 Pfam PF00069 Protein kinase domain 347 592 9.1E-30 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UA74_11665 69be96953ecacb51f281a769d3dcf821 944 Gene3D G3DSA:3.30.200.20 299 434 9.0E-104 T 12-10-2018 UA74_11665 69be96953ecacb51f281a769d3dcf821 944 SUPERFAMILY SSF48452 707 814 1.05E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_25315 f5c20c9f39426338c511b9929f6837c5 269 SUPERFAMILY SSF55729 116 263 1.27E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_25315 f5c20c9f39426338c511b9929f6837c5 269 Pfam PF00583 Acetyltransferase (GNAT) family 152 251 3.5E-13 T 12-10-2018 IPR000182 GNAT domain UA74_25315 f5c20c9f39426338c511b9929f6837c5 269 Gene3D G3DSA:3.40.630.30 24 267 5.6E-24 T 12-10-2018 UA74_03170 49247f5b0dde0915d98e438eb5789368 416 Pfam PF13796 Putative sensor 30 196 1.9E-16 T 12-10-2018 IPR025828 Putative sensor domain UA74_03170 49247f5b0dde0915d98e438eb5789368 416 SUPERFAMILY SSF55874 308 412 1.92E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_03170 49247f5b0dde0915d98e438eb5789368 416 Gene3D G3DSA:3.30.565.10 301 413 2.4E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_03170 49247f5b0dde0915d98e438eb5789368 416 Pfam PF07730 Histidine kinase 225 292 2.4E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 SMART SM00418 117 200 4.2E-16 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 SUPERFAMILY SSF46785 114 219 3.51E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 Gene3D G3DSA:1.10.10.10 104 216 7.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 Gene3D G3DSA:3.30.530.20 221 371 3.0E-34 T 12-10-2018 IPR023393 START-like domain superfamily UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 231 369 9.0E-19 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 Pfam PF12840 Helix-turn-helix domain 116 175 2.6E-15 T 12-10-2018 UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 152 167 3.1E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 167 182 3.1E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 119 134 3.1E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_21940 f38c2a1027eb86e1aa023ca1a7df42f5 379 SUPERFAMILY SSF55961 215 375 1.33E-28 T 12-10-2018 UA74_27030 4f69e0de3eb1ddfe6e11193a153f25ad 296 SUPERFAMILY SSF51658 59 294 6.36E-37 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_27030 4f69e0de3eb1ddfe6e11193a153f25ad 296 Gene3D G3DSA:3.20.20.150 52 296 9.1E-65 T 12-10-2018 UA74_27030 4f69e0de3eb1ddfe6e11193a153f25ad 296 Pfam PF01261 Xylose isomerase-like TIM barrel 78 252 1.0E-16 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_19260 0b4b065a5e4b134f81dc74402560095d 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 2.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_19260 0b4b065a5e4b134f81dc74402560095d 189 SUPERFAMILY SSF46689 1 71 8.48E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_19260 0b4b065a5e4b134f81dc74402560095d 189 Gene3D G3DSA:1.10.357.10 1 175 4.4E-30 T 12-10-2018 UA74_09665 b105a64557bf644be9caa61b927b3231 281 Pfam PF13560 Helix-turn-helix domain 10 69 2.7E-13 T 12-10-2018 UA74_09665 b105a64557bf644be9caa61b927b3231 281 SMART SM00530 14 69 4.3E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_09665 b105a64557bf644be9caa61b927b3231 281 SUPERFAMILY SSF47413 8 68 2.73E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_09665 b105a64557bf644be9caa61b927b3231 281 Gene3D G3DSA:1.10.260.40 5 71 6.9E-12 T 12-10-2018 UA74_28670 4382a8d70cb80ff5e1112a9ceb592271 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_28670 4382a8d70cb80ff5e1112a9ceb592271 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_28670 4382a8d70cb80ff5e1112a9ceb592271 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_28670 4382a8d70cb80ff5e1112a9ceb592271 256 SUPERFAMILY SSF51735 3 224 6.39E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_28670 4382a8d70cb80ff5e1112a9ceb592271 256 Pfam PF00106 short chain dehydrogenase 4 191 2.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_28670 4382a8d70cb80ff5e1112a9ceb592271 256 Gene3D G3DSA:3.40.50.720 2 254 4.0E-58 T 12-10-2018 UA74_18870 caa6e7b5b3e4d606f0a19b681ad88424 432 SUPERFAMILY SSF53850 25 423 3.98E-58 T 12-10-2018 UA74_18870 caa6e7b5b3e4d606f0a19b681ad88424 432 Pfam PF13416 Bacterial extracellular solute-binding protein 55 367 7.5E-24 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_18870 caa6e7b5b3e4d606f0a19b681ad88424 432 Gene3D G3DSA:3.40.190.10 152 419 4.9E-120 T 12-10-2018 UA74_18870 caa6e7b5b3e4d606f0a19b681ad88424 432 Gene3D G3DSA:3.40.190.10 69 393 4.9E-120 T 12-10-2018 UA74_22080 f8276f968102ff961032f62727184203 562 Gene3D G3DSA:3.90.1720.10 21 175 2.0E-11 T 12-10-2018 UA74_22080 f8276f968102ff961032f62727184203 562 SUPERFAMILY SSF89372 216 456 4.19E-13 T 12-10-2018 UA74_22080 f8276f968102ff961032f62727184203 562 SUPERFAMILY SSF54001 70 160 1.72E-6 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UA74_27050 9b8e7122226add237bbfcbe099e7d160 389 Gene3D G3DSA:3.20.20.150 28 298 5.8E-14 T 12-10-2018 UA74_27050 9b8e7122226add237bbfcbe099e7d160 389 SUPERFAMILY SSF51658 7 249 3.08E-28 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_27050 9b8e7122226add237bbfcbe099e7d160 389 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 200 207 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 UA74_27050 9b8e7122226add237bbfcbe099e7d160 389 Pfam PF01261 Xylose isomerase-like TIM barrel 40 222 8.3E-9 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_06400 429e3660e4c6bb721e1e08716a93f1ed 250 Pfam PF08241 Methyltransferase domain 48 138 1.5E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_06400 429e3660e4c6bb721e1e08716a93f1ed 250 SUPERFAMILY SSF53335 26 195 2.48E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_06400 429e3660e4c6bb721e1e08716a93f1ed 250 Gene3D G3DSA:3.40.50.150 21 195 1.5E-33 T 12-10-2018 UA74_14680 bb98566687282aa29818088a408b4100 349 SUPERFAMILY SSF46785 16 75 2.84E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14680 bb98566687282aa29818088a408b4100 349 Pfam PF13280 WYL domain 152 327 1.6E-22 T 12-10-2018 IPR026881 WYL domain UA74_14680 bb98566687282aa29818088a408b4100 349 ProSitePatterns PS00894 DeoR-type HTH domain signature. 18 52 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_14680 bb98566687282aa29818088a408b4100 349 Gene3D G3DSA:1.10.10.10 6 77 5.0E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14680 bb98566687282aa29818088a408b4100 349 Pfam PF08279 HTH domain 18 73 2.3E-11 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 UA74_04540 cb33aaa413a64eb3b0aae751b336d1da 282 PIRSF PIRSF020623 1 277 3.1E-64 T 12-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 UA74_04540 cb33aaa413a64eb3b0aae751b336d1da 282 Pfam PF07848 PaaX-like protein 8 76 6.9E-16 T 12-10-2018 IPR012906 PaaX-like, N-terminal UA74_04540 cb33aaa413a64eb3b0aae751b336d1da 282 Gene3D G3DSA:1.10.10.10 7 89 7.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04540 cb33aaa413a64eb3b0aae751b336d1da 282 Pfam PF08223 PaaX-like protein C-terminal domain 167 259 1.1E-23 T 12-10-2018 IPR013225 PaaX-like, C-terminal UA74_08290 33fb5e2221bd05f6b5a3c0968f0380e8 420 SUPERFAMILY SSF53686 17 406 1.44E-84 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_08290 33fb5e2221bd05f6b5a3c0968f0380e8 420 Gene3D G3DSA:3.40.50.1100 68 393 1.5E-100 T 12-10-2018 UA74_08290 33fb5e2221bd05f6b5a3c0968f0380e8 420 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 87 388 5.0E-65 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_08290 33fb5e2221bd05f6b5a3c0968f0380e8 420 TIGRFAM TIGR00260 thrC: threonine synthase 66 394 1.5E-84 T 12-10-2018 IPR004450 Threonine synthase-like UA74_08290 33fb5e2221bd05f6b5a3c0968f0380e8 420 Gene3D G3DSA:3.40.50.1100 120 217 1.5E-100 T 12-10-2018 UA74_29335 ea38fa6b0181a68d965fc8ce98533d92 221 SUPERFAMILY SSF56784 24 209 5.35E-28 T 12-10-2018 IPR036412 HAD-like superfamily UA74_29335 ea38fa6b0181a68d965fc8ce98533d92 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 113 199 1.2E-8 T 12-10-2018 UA74_29335 ea38fa6b0181a68d965fc8ce98533d92 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 104 200 1.3E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_29335 ea38fa6b0181a68d965fc8ce98533d92 221 Gene3D G3DSA:3.40.50.1000 23 218 3.4E-30 T 12-10-2018 IPR023214 HAD superfamily UA74_29335 ea38fa6b0181a68d965fc8ce98533d92 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 118 131 2.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_29335 ea38fa6b0181a68d965fc8ce98533d92 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 166 186 2.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_29335 ea38fa6b0181a68d965fc8ce98533d92 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 148 164 2.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_29335 ea38fa6b0181a68d965fc8ce98533d92 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 24 35 2.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_13445 9726b675dcbf5782b9bea7741e237f3f 405 PRINTS PR00758 Arsenical pump membrane protein signature 169 192 4.6E-14 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UA74_13445 9726b675dcbf5782b9bea7741e237f3f 405 PRINTS PR00758 Arsenical pump membrane protein signature 96 120 4.6E-14 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UA74_13445 9726b675dcbf5782b9bea7741e237f3f 405 PRINTS PR00758 Arsenical pump membrane protein signature 344 369 4.6E-14 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UA74_13445 9726b675dcbf5782b9bea7741e237f3f 405 PRINTS PR00758 Arsenical pump membrane protein signature 377 401 4.6E-14 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UA74_13445 9726b675dcbf5782b9bea7741e237f3f 405 Pfam PF03600 Citrate transporter 17 332 1.5E-18 T 12-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 UA74_24705 16ff1568b59bc47346cee256a9184aaf 495 Pfam PF15975 Flotillin 364 473 6.6E-11 T 12-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 UA74_24705 16ff1568b59bc47346cee256a9184aaf 495 Gene3D G3DSA:3.30.479.30 76 190 1.0E-24 T 12-10-2018 UA74_24705 16ff1568b59bc47346cee256a9184aaf 495 Pfam PF01145 SPFH domain / Band 7 family 29 215 3.5E-19 T 12-10-2018 IPR001107 Band 7 domain UA74_24705 16ff1568b59bc47346cee256a9184aaf 495 SUPERFAMILY SSF117892 67 204 4.58E-24 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily UA74_12560 951a8721f514d96347752ec80b203ef7 281 Gene3D G3DSA:1.10.260.40 6 75 3.2E-5 T 12-10-2018 UA74_12560 951a8721f514d96347752ec80b203ef7 281 SUPERFAMILY SSF47413 10 74 1.1E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_12560 951a8721f514d96347752ec80b203ef7 281 Pfam PF13560 Helix-turn-helix domain 14 75 1.9E-10 T 12-10-2018 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 385 1.8E-50 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 Gene3D G3DSA:1.10.540.10 13 123 2.1E-38 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 120 2.0E-30 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 PIRSF PIRSF016578 6 387 4.1E-25 T 12-10-2018 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 128 140 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 2.8E-28 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 Gene3D G3DSA:2.40.110.10 126 239 2.4E-41 T 12-10-2018 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 SUPERFAMILY SSF47203 233 386 5.64E-59 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 SUPERFAMILY SSF56645 8 247 1.7E-75 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_26760 00755c3d9361566ab102c378ad52d0c1 387 Gene3D G3DSA:1.20.140.10 240 387 1.5E-57 T 12-10-2018 UA74_24225 fdfdfee4ae7a83f33624c2a16766408b 273 SUPERFAMILY SSF161098 34 260 1.7E-46 T 12-10-2018 IPR035906 MetI-like superfamily UA74_24225 fdfdfee4ae7a83f33624c2a16766408b 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 265 1.9E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_24225 fdfdfee4ae7a83f33624c2a16766408b 273 Gene3D G3DSA:1.10.3720.10 30 271 7.5E-53 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20050 c70b4b21f59cc68e23666900b52ef130 126 SUPERFAMILY SSF82607 26 116 6.28E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_20050 c70b4b21f59cc68e23666900b52ef130 126 Pfam PF02575 YbaB/EbfC DNA-binding family 41 117 3.9E-9 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_20050 c70b4b21f59cc68e23666900b52ef130 126 Gene3D G3DSA:3.30.1310.10 24 123 2.5E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_23640 0e40d9c70d3b3f131e9c286f1d7a1d3a 160 Pfam PF03780 Asp23 family, cell envelope-related function 35 145 1.0E-32 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 UA74_27540 6b85475bbcd60cd16a0d14333d087697 265 SUPERFAMILY SSF56219 2 264 2.36E-72 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_27540 6b85475bbcd60cd16a0d14333d087697 265 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 256 2.9E-19 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase UA74_27540 6b85475bbcd60cd16a0d14333d087697 265 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 5 263 1.9E-71 T 12-10-2018 UA74_27540 6b85475bbcd60cd16a0d14333d087697 265 Gene3D G3DSA:3.60.10.10 1 265 6.4E-77 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_27540 6b85475bbcd60cd16a0d14333d087697 265 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 264 3.0E-73 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 UA74_14650 8bc25e6ce506c8d6b3e1f5818acaf246 210 Pfam PF01205 Uncharacterized protein family UPF0029 19 123 2.7E-30 T 12-10-2018 IPR001498 Impact, N-terminal UA74_14650 8bc25e6ce506c8d6b3e1f5818acaf246 210 Gene3D G3DSA:3.30.230.30 1 131 1.6E-49 T 12-10-2018 IPR036956 Impact, N-terminal domain superfamily UA74_14650 8bc25e6ce506c8d6b3e1f5818acaf246 210 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 1.3E-10 T 12-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal UA74_14650 8bc25e6ce506c8d6b3e1f5818acaf246 210 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 12-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site UA74_14650 8bc25e6ce506c8d6b3e1f5818acaf246 210 SUPERFAMILY SSF54211 3 131 4.55E-42 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_14650 8bc25e6ce506c8d6b3e1f5818acaf246 210 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 202 1.5E-57 T 12-10-2018 IPR015796 Impact family, bacterial/archaeal UA74_14650 8bc25e6ce506c8d6b3e1f5818acaf246 210 SUPERFAMILY SSF54980 135 200 2.16E-9 T 12-10-2018 IPR035647 EF-G domain III/V-like UA74_17035 ed2938c80da191d5f3bcfb7cc12a7bb7 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 328 3.4E-38 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_17035 ed2938c80da191d5f3bcfb7cc12a7bb7 331 SUPERFAMILY SSF161098 109 310 2.62E-17 T 12-10-2018 IPR035906 MetI-like superfamily UA74_17035 ed2938c80da191d5f3bcfb7cc12a7bb7 331 Gene3D G3DSA:1.10.3720.10 99 320 1.6E-20 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04130 f6bc20298d271d0bbc4a2ad1e1f54b75 288 SUPERFAMILY SSF50494 46 286 1.27E-47 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_04130 f6bc20298d271d0bbc4a2ad1e1f54b75 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 140 154 3.5E-14 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_04130 f6bc20298d271d0bbc4a2ad1e1f54b75 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 225 237 3.5E-14 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_04130 f6bc20298d271d0bbc4a2ad1e1f54b75 288 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 82 97 3.5E-14 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_04130 f6bc20298d271d0bbc4a2ad1e1f54b75 288 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 226 237 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site UA74_04130 f6bc20298d271d0bbc4a2ad1e1f54b75 288 Pfam PF00089 Trypsin 56 258 9.8E-34 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_04130 f6bc20298d271d0bbc4a2ad1e1f54b75 288 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 92 97 - T 12-10-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 UA74_04130 f6bc20298d271d0bbc4a2ad1e1f54b75 288 SMART SM00020 55 282 1.5E-32 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_04130 f6bc20298d271d0bbc4a2ad1e1f54b75 288 Gene3D G3DSA:2.40.10.10 49 288 1.0E-39 T 12-10-2018 UA74_12695 288a671b8de3c26cab4d9a364acb04e0 180 SUPERFAMILY SSF50800 2 169 3.19E-39 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily UA74_12695 288a671b8de3c26cab4d9a364acb04e0 180 Gene3D G3DSA:2.40.33.20 3 178 6.5E-31 T 12-10-2018 UA74_12695 288a671b8de3c26cab4d9a364acb04e0 180 Pfam PF03473 MOSC domain 57 166 3.3E-5 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 UA74_04080 f0e23523942314dea6bfffc1fc992a64 217 Pfam PF03006 Haemolysin-III related 7 208 3.5E-44 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 UA74_04080 f0e23523942314dea6bfffc1fc992a64 217 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 8 214 2.8E-59 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 UA74_24955 c6610d0f861c58466093075029b36023 63 Pfam PF04149 Domain of unknown function (DUF397) 9 62 7.8E-23 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_15920 5f925c9aef79f31919065c05f0b8bb52 523 Pfam PF02384 N-6 DNA Methylase 165 484 2.8E-94 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_15920 5f925c9aef79f31919065c05f0b8bb52 523 Pfam PF12161 HsdM N-terminal domain 8 151 3.6E-16 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain UA74_15920 5f925c9aef79f31919065c05f0b8bb52 523 Gene3D G3DSA:1.20.1260.30 2 155 2.1E-15 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily UA74_15920 5f925c9aef79f31919065c05f0b8bb52 523 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 294 300 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_15920 5f925c9aef79f31919065c05f0b8bb52 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 189 205 1.6E-15 T 12-10-2018 UA74_15920 5f925c9aef79f31919065c05f0b8bb52 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 213 227 1.6E-15 T 12-10-2018 UA74_15920 5f925c9aef79f31919065c05f0b8bb52 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 291 303 1.6E-15 T 12-10-2018 UA74_15920 5f925c9aef79f31919065c05f0b8bb52 523 Gene3D G3DSA:3.40.50.150 166 452 9.0E-89 T 12-10-2018 UA74_15920 5f925c9aef79f31919065c05f0b8bb52 523 SUPERFAMILY SSF53335 6 518 3.35E-116 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_00890 e4e3da8d9330efb8c3bc867fc6cc124a 170 Gene3D G3DSA:1.10.10.10 14 153 5.8E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_00890 e4e3da8d9330efb8c3bc867fc6cc124a 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 1.2E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00890 e4e3da8d9330efb8c3bc867fc6cc124a 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 1.2E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00890 e4e3da8d9330efb8c3bc867fc6cc124a 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 1.2E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00890 e4e3da8d9330efb8c3bc867fc6cc124a 170 SMART SM00347 40 140 3.6E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_00890 e4e3da8d9330efb8c3bc867fc6cc124a 170 SUPERFAMILY SSF46785 18 155 6.07E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_00890 e4e3da8d9330efb8c3bc867fc6cc124a 170 Pfam PF13463 Winged helix DNA-binding domain 68 113 3.3E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_25850 2502cd79f08f7a572aca555c5e4de1f6 233 Pfam PF09339 IclR helix-turn-helix domain 10 56 2.0E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_25850 2502cd79f08f7a572aca555c5e4de1f6 233 SMART SM00346 7 92 1.5E-20 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_25850 2502cd79f08f7a572aca555c5e4de1f6 233 Gene3D G3DSA:1.10.10.10 2 71 6.7E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_25850 2502cd79f08f7a572aca555c5e4de1f6 233 Gene3D G3DSA:3.30.450.40 72 232 1.4E-36 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_25850 2502cd79f08f7a572aca555c5e4de1f6 233 SUPERFAMILY SSF55781 63 233 2.49E-35 T 12-10-2018 UA74_25850 2502cd79f08f7a572aca555c5e4de1f6 233 SUPERFAMILY SSF46785 7 74 6.95E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_25850 2502cd79f08f7a572aca555c5e4de1f6 233 Pfam PF01614 Bacterial transcriptional regulator 124 229 2.5E-14 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 Gene3D G3DSA:2.40.30.10 316 420 6.0E-26 T 12-10-2018 UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 SUPERFAMILY SSF50447 223 313 8.73E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 Gene3D G3DSA:3.40.50.300 2 221 5.3E-64 T 12-10-2018 UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 Gene3D G3DSA:2.40.30.10 224 313 2.7E-22 T 12-10-2018 UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 63 78 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.0E-12 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 PRINTS PR00315 GTP-binding elongation factor signature 70 78 1.0E-12 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 PRINTS PR00315 GTP-binding elongation factor signature 90 100 1.0E-12 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 PRINTS PR00315 GTP-binding elongation factor signature 106 117 1.0E-12 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 PRINTS PR00315 GTP-binding elongation factor signature 143 152 1.0E-12 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 SUPERFAMILY SSF52540 9 217 4.57E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 SUPERFAMILY SSF50465 319 420 1.2E-22 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 10 420 1.2E-163 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 UA74_24545 aae363555d2aa6c71f67a225c6f51094 459 Pfam PF00009 Elongation factor Tu GTP binding domain 11 195 2.8E-37 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UA74_13665 10004d11cf49630fa8b6885f34019b75 198 SUPERFAMILY SSF52540 16 191 2.52E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13665 10004d11cf49630fa8b6885f34019b75 198 Gene3D G3DSA:3.40.50.300 8 193 4.3E-18 T 12-10-2018 UA74_13665 10004d11cf49630fa8b6885f34019b75 198 Pfam PF03029 Conserved hypothetical ATP binding protein 21 164 2.6E-24 T 12-10-2018 IPR004130 GPN-loop GTPase UA74_12110 ee4f809776fd7f99af2dd561b51d0dda 152 SUPERFAMILY SSF51261 3 148 2.96E-37 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_12110 ee4f809776fd7f99af2dd561b51d0dda 152 Gene3D G3DSA:2.70.70.10 1 148 1.0E-42 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_12110 ee4f809776fd7f99af2dd561b51d0dda 152 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 67 79 - T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UA74_12110 ee4f809776fd7f99af2dd561b51d0dda 152 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 5 122 7.7E-32 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UA74_12110 ee4f809776fd7f99af2dd561b51d0dda 152 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 4 125 2.3E-40 T 12-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UA74_12265 22416c6dcee5755ae9d0602a4360e6cb 670 Hamap MF_00983 Probable primosomal protein N' [priA]. 26 669 20.063 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 UA74_12265 22416c6dcee5755ae9d0602a4360e6cb 670 Gene3D G3DSA:1.10.8.630 19 130 2.9E-17 T 12-10-2018 UA74_12265 22416c6dcee5755ae9d0602a4360e6cb 670 SUPERFAMILY SSF52540 185 262 1.33E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12265 22416c6dcee5755ae9d0602a4360e6cb 670 Gene3D G3DSA:3.40.50.300 159 327 2.1E-25 T 12-10-2018 UA74_13320 275bcec7e29f6fecbcee77aeae981dbd 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 75 337 2.4E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_04595 1ce24651003d971a9032ffaa39cb65da 130 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 5.3E-10 T 12-10-2018 UA74_04595 1ce24651003d971a9032ffaa39cb65da 130 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 5.3E-10 T 12-10-2018 UA74_04595 1ce24651003d971a9032ffaa39cb65da 130 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 5.3E-10 T 12-10-2018 UA74_04595 1ce24651003d971a9032ffaa39cb65da 130 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 124 14.144 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 UA74_04595 1ce24651003d971a9032ffaa39cb65da 130 Pfam PF02416 mttA/Hcf106 family 5 41 1.6E-9 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 UA74_04595 1ce24651003d971a9032ffaa39cb65da 130 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 5 82 2.9E-18 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 UA74_07870 f7145a94a1ba17f753cdbad295920b09 1667 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 100 1663 0.0 T 12-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 UA74_07870 f7145a94a1ba17f753cdbad295920b09 1667 SUPERFAMILY SSF51735 997 1265 7.88E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_07870 f7145a94a1ba17f753cdbad295920b09 1667 SUPERFAMILY SSF53223 811 992 2.01E-21 T 12-10-2018 UA74_07870 f7145a94a1ba17f753cdbad295920b09 1667 PIRSF PIRSF036761 26 1667 0.0 T 12-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 UA74_24240 d256dbeb0518c680357f7bbd8d22d487 156 Gene3D G3DSA:1.20.120.520 2 149 8.6E-24 T 12-10-2018 UA74_24240 d256dbeb0518c680357f7bbd8d22d487 156 Pfam PF01814 Hemerythrin HHE cation binding domain 14 138 8.2E-18 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 UA74_06505 e1dfc9477412b8bc32ff7aa7a736f55f 256 Pfam PF00975 Thioesterase domain 25 243 1.1E-42 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UA74_06505 e1dfc9477412b8bc32ff7aa7a736f55f 256 SUPERFAMILY SSF53474 14 247 1.63E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06505 e1dfc9477412b8bc32ff7aa7a736f55f 256 Gene3D G3DSA:3.40.50.1820 7 250 1.7E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06505 e1dfc9477412b8bc32ff7aa7a736f55f 256 SMART SM00824 Thioesterase 27 210 5.8E-4 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 Pfam PF00082 Subtilase family 186 650 4.2E-40 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 Gene3D G3DSA:3.40.50.200 488 682 3.3E-30 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 267 277 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 191 202 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 SUPERFAMILY SSF52743 132 680 3.53E-63 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 614 624 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 Gene3D G3DSA:3.40.50.200 166 464 8.4E-38 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 Pfam PF02225 PA domain 449 540 3.1E-5 T 12-10-2018 IPR003137 PA domain UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 PRINTS PR00723 Subtilisin serine protease family (S8) signature 613 629 1.2E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 PRINTS PR00723 Subtilisin serine protease family (S8) signature 263 276 1.2E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_25915 dc96f9e07ac957cb01e6975859465fe7 1116 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 205 1.2E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_28425 47e3e5ab05c9780dcfa43d1b4650f1a0 143 Pfam PF01967 MoaC family 1 134 9.3E-49 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28425 47e3e5ab05c9780dcfa43d1b4650f1a0 143 Gene3D G3DSA:3.30.70.640 1 143 2.3E-56 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28425 47e3e5ab05c9780dcfa43d1b4650f1a0 143 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 1 135 1.6E-52 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_28425 47e3e5ab05c9780dcfa43d1b4650f1a0 143 SUPERFAMILY SSF55040 1 139 2.88E-49 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_15575 d68cae6dbe541db06745b9629503468f 159 Gene3D G3DSA:1.10.10.10 1 151 2.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_15575 d68cae6dbe541db06745b9629503468f 159 SUPERFAMILY SSF46785 19 147 6.39E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_15575 d68cae6dbe541db06745b9629503468f 159 SMART SM00347 38 140 2.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_15575 d68cae6dbe541db06745b9629503468f 159 Pfam PF12802 MarR family 45 102 5.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_29885 0f6262aa1cff81385ec3f1cdec758200 469 Gene3D G3DSA:3.40.630.10 88 431 2.6E-120 T 12-10-2018 UA74_29885 0f6262aa1cff81385ec3f1cdec758200 469 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 87 412 9.9E-72 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 UA74_29885 0f6262aa1cff81385ec3f1cdec758200 469 SUPERFAMILY SSF53187 81 445 5.11E-54 T 12-10-2018 UA74_29885 0f6262aa1cff81385ec3f1cdec758200 469 Gene3D G3DSA:3.30.70.360 233 351 2.6E-120 T 12-10-2018 UA74_29885 0f6262aa1cff81385ec3f1cdec758200 469 Pfam PF07687 Peptidase dimerisation domain 236 328 1.1E-9 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain UA74_29885 0f6262aa1cff81385ec3f1cdec758200 469 SUPERFAMILY SSF55031 233 343 7.33E-24 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UA74_02420 9a2dc2b6920b9fa65010ad565fbc0a9a 77 Pfam PF12728 Helix-turn-helix domain 16 64 8.2E-11 T 12-10-2018 UA74_02420 9a2dc2b6920b9fa65010ad565fbc0a9a 77 Gene3D G3DSA:1.10.1660.10 16 75 3.7E-11 T 12-10-2018 UA74_02420 9a2dc2b6920b9fa65010ad565fbc0a9a 77 SUPERFAMILY SSF46955 15 66 5.95E-11 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_02420 9a2dc2b6920b9fa65010ad565fbc0a9a 77 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 16 64 1.4E-10 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 SMART SM00448 3 115 6.8E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 SMART SM00421 150 207 3.7E-22 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 5.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 5.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 5.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 SUPERFAMILY SSF46894 141 213 4.08E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 Pfam PF00072 Response regulator receiver domain 5 116 4.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 1.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 Gene3D G3DSA:3.40.50.12740 3 213 6.2E-69 T 12-10-2018 UA74_23950 dc8e1018548fdc600843e0d7787e5b9e 221 SUPERFAMILY SSF52172 2 131 3.7E-34 T 12-10-2018 IPR011006 CheY-like superfamily UA74_13395 d0a4249152a069c300b35eb694236ceb 296 Pfam PF13560 Helix-turn-helix domain 17 82 1.8E-11 T 12-10-2018 UA74_13395 d0a4249152a069c300b35eb694236ceb 296 SUPERFAMILY SSF47413 12 78 5.2E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_13395 d0a4249152a069c300b35eb694236ceb 296 SMART SM00530 20 80 1.4E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_13395 d0a4249152a069c300b35eb694236ceb 296 Gene3D G3DSA:1.10.260.40 9 80 1.5E-6 T 12-10-2018 UA74_11725 3cf190d3358a7d89ee11ddd0d818f48a 408 Pfam PF13579 Glycosyl transferase 4-like domain 22 191 2.1E-32 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_11725 3cf190d3358a7d89ee11ddd0d818f48a 408 SUPERFAMILY SSF53756 1 392 1.28E-83 T 12-10-2018 UA74_11725 3cf190d3358a7d89ee11ddd0d818f48a 408 Gene3D G3DSA:3.40.50.2000 192 372 4.1E-104 T 12-10-2018 UA74_11725 3cf190d3358a7d89ee11ddd0d818f48a 408 Pfam PF00534 Glycosyl transferases group 1 208 368 1.1E-32 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_11725 3cf190d3358a7d89ee11ddd0d818f48a 408 Gene3D G3DSA:3.40.50.2000 5 389 4.1E-104 T 12-10-2018 UA74_15250 f97feb8b9b8a881edfc1fbde20724523 208 Gene3D G3DSA:3.40.50.720 2 206 3.1E-40 T 12-10-2018 UA74_15250 f97feb8b9b8a881edfc1fbde20724523 208 SUPERFAMILY SSF51735 2 201 1.72E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_15250 f97feb8b9b8a881edfc1fbde20724523 208 Pfam PF13460 NAD(P)H-binding 7 198 1.4E-23 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_29090 8fefa394d48dfa84f35d1841b3e2f118 282 Pfam PF13560 Helix-turn-helix domain 12 73 7.1E-14 T 12-10-2018 UA74_29090 8fefa394d48dfa84f35d1841b3e2f118 282 Gene3D G3DSA:1.10.260.40 7 73 1.6E-8 T 12-10-2018 UA74_29090 8fefa394d48dfa84f35d1841b3e2f118 282 SMART SM00530 15 70 3.0E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_29090 8fefa394d48dfa84f35d1841b3e2f118 282 SUPERFAMILY SSF47413 9 66 2.36E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_22980 62105ca623437c095a48fa6249c59083 254 Pfam PF12706 Beta-lactamase superfamily domain 32 220 4.9E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_22980 62105ca623437c095a48fa6249c59083 254 Gene3D G3DSA:3.60.15.10 1 253 3.3E-69 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_22980 62105ca623437c095a48fa6249c59083 254 SMART SM00849 21 198 0.0048 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_22980 62105ca623437c095a48fa6249c59083 254 SUPERFAMILY SSF56281 6 251 1.1E-49 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_21990 f647142d5029dbc5f0b9b76e148a215f 118 Gene3D G3DSA:2.30.31.20 1 114 4.4E-44 T 12-10-2018 IPR038658 Sporulation-specific cell division protein SsgB superfamily UA74_21990 f647142d5029dbc5f0b9b76e148a215f 118 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 3 99 1.7E-35 T 12-10-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 UA74_24670 1230e8633ed794ab0d3752aebe08d217 281 SUPERFAMILY SSF51730 1 277 2.35E-88 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like UA74_24670 1230e8633ed794ab0d3752aebe08d217 281 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 2 274 5.3E-90 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 UA74_24670 1230e8633ed794ab0d3752aebe08d217 281 Gene3D G3DSA:3.20.20.220 1 280 2.2E-93 T 12-10-2018 UA74_24670 1230e8633ed794ab0d3752aebe08d217 281 Pfam PF02219 Methylenetetrahydrofolate reductase 2 275 3.1E-89 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 UA74_26845 69730f73493fbc418f615a859fb88a47 319 SUPERFAMILY SSF51569 21 310 8.06E-67 T 12-10-2018 UA74_26845 69730f73493fbc418f615a859fb88a47 319 Pfam PF00682 HMGL-like 25 296 5.0E-47 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 UA74_26845 69730f73493fbc418f615a859fb88a47 319 Gene3D G3DSA:3.20.20.70 19 318 8.1E-122 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_10230 37ecb323c2b12437ef0c3864a5f252e5 674 Pfam PF12161 HsdM N-terminal domain 26 154 5.8E-19 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain UA74_10230 37ecb323c2b12437ef0c3864a5f252e5 674 SUPERFAMILY SSF53335 25 671 3.75E-114 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_10230 37ecb323c2b12437ef0c3864a5f252e5 674 Gene3D G3DSA:3.40.50.150 167 479 4.0E-93 T 12-10-2018 UA74_10230 37ecb323c2b12437ef0c3864a5f252e5 674 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 189 205 1.3E-13 T 12-10-2018 UA74_10230 37ecb323c2b12437ef0c3864a5f252e5 674 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 222 236 1.3E-13 T 12-10-2018 UA74_10230 37ecb323c2b12437ef0c3864a5f252e5 674 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 294 306 1.3E-13 T 12-10-2018 UA74_10230 37ecb323c2b12437ef0c3864a5f252e5 674 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 297 303 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_10230 37ecb323c2b12437ef0c3864a5f252e5 674 Pfam PF02384 N-6 DNA Methylase 166 462 3.9E-60 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UA74_29965 63c795c4b12fee1a19afbba0ebd05c10 188 Pfam PF03551 Transcriptional regulator PadR-like family 6 85 6.6E-19 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_29965 63c795c4b12fee1a19afbba0ebd05c10 188 SUPERFAMILY SSF46785 2 173 1.62E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_29965 63c795c4b12fee1a19afbba0ebd05c10 188 Gene3D G3DSA:1.10.10.10 1 96 1.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26885 39fde24fbe9b86e458896e0a0a502be6 660 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 76 347 8.0E-50 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_26885 39fde24fbe9b86e458896e0a0a502be6 660 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 374 614 8.4E-30 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_26885 39fde24fbe9b86e458896e0a0a502be6 660 SUPERFAMILY SSF53474 43 396 1.76E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26885 39fde24fbe9b86e458896e0a0a502be6 660 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 74 250 1.5E-22 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 UA74_26885 39fde24fbe9b86e458896e0a0a502be6 660 SUPERFAMILY SSF49785 450 625 4.04E-28 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_26885 39fde24fbe9b86e458896e0a0a502be6 660 SMART SM00939 362 620 9.4E-37 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_26885 39fde24fbe9b86e458896e0a0a502be6 660 Gene3D G3DSA:3.40.50.1820 60 253 2.0E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26885 39fde24fbe9b86e458896e0a0a502be6 660 Gene3D G3DSA:3.40.50.1820 286 416 9.3E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_09700 2d8344585ddcafa048069447a7f3d428 248 PIRSF PIRSF004848 7 248 4.5E-59 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 UA74_09700 2d8344585ddcafa048069447a7f3d428 248 SUPERFAMILY SSF51419 16 243 1.07E-60 T 12-10-2018 IPR029066 PLP-binding barrel UA74_09700 2d8344585ddcafa048069447a7f3d428 248 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 20 245 2.3E-40 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 UA74_09700 2d8344585ddcafa048069447a7f3d428 248 Pfam PF01168 Alanine racemase, N-terminal domain 20 246 1.9E-19 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_09700 2d8344585ddcafa048069447a7f3d428 248 Gene3D G3DSA:3.20.20.10 2 248 1.1E-71 T 12-10-2018 IPR029066 PLP-binding barrel UA74_09700 2d8344585ddcafa048069447a7f3d428 248 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 92 106 - T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 UA74_09700 2d8344585ddcafa048069447a7f3d428 248 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 18 244 26.414 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 UA74_03380 dd0eed328bd3547d2526f2dc96f970f1 338 Gene3D G3DSA:3.40.50.720 1 148 3.4E-18 T 12-10-2018 UA74_03380 dd0eed328bd3547d2526f2dc96f970f1 338 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 123 5.4E-6 T 12-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 UA74_03380 dd0eed328bd3547d2526f2dc96f970f1 338 SUPERFAMILY SSF51735 1 140 1.14E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_30305 8e026094f1de6434897d23db485c1f1a 356 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 32 247 1.1E-57 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_30305 8e026094f1de6434897d23db485c1f1a 356 Pfam PF02096 60Kd inner membrane protein 32 247 3.4E-52 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 UA74_06515 efc0462db1dd2d367cb1bdd29c36de7a 367 SUPERFAMILY SSF51905 178 354 1.34E-7 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06515 efc0462db1dd2d367cb1bdd29c36de7a 367 SUPERFAMILY SSF51905 10 207 5.83E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06515 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 174 198 4.0E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_06515 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 4.0E-9 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_06515 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.4E-8 T 12-10-2018 UA74_06515 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 2.4E-8 T 12-10-2018 UA74_06515 efc0462db1dd2d367cb1bdd29c36de7a 367 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 302 2.4E-8 T 12-10-2018 UA74_06515 efc0462db1dd2d367cb1bdd29c36de7a 367 Gene3D G3DSA:3.50.50.60 2 359 4.1E-105 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_06515 efc0462db1dd2d367cb1bdd29c36de7a 367 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 13 210 3.2E-20 T 12-10-2018 UA74_09890 c99bd3c8ccaeed59a722b3765eb42c80 376 Gene3D G3DSA:3.90.1150.10 23 365 7.8E-124 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_09890 c99bd3c8ccaeed59a722b3765eb42c80 376 SUPERFAMILY SSF53383 37 366 1.67E-69 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_09890 c99bd3c8ccaeed59a722b3765eb42c80 376 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 20 368 2.6E-94 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UA74_09890 c99bd3c8ccaeed59a722b3765eb42c80 376 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 UA74_09890 c99bd3c8ccaeed59a722b3765eb42c80 376 Gene3D G3DSA:3.40.640.10 60 283 7.8E-124 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_09890 c99bd3c8ccaeed59a722b3765eb42c80 376 Pfam PF00155 Aminotransferase class I and II 38 363 1.5E-51 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_09890 c99bd3c8ccaeed59a722b3765eb42c80 376 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 18 370 52.805 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UA74_22750 f17bafbdea4ae8c65c010a09f29235cd 361 SUPERFAMILY SSF103473 1 351 1.06E-57 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_22750 f17bafbdea4ae8c65c010a09f29235cd 361 Pfam PF07690 Major Facilitator Superfamily 4 270 3.4E-31 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_22750 f17bafbdea4ae8c65c010a09f29235cd 361 Gene3D G3DSA:1.20.1250.20 1 121 1.1E-23 T 12-10-2018 UA74_22750 f17bafbdea4ae8c65c010a09f29235cd 361 Gene3D G3DSA:1.20.1250.20 151 350 3.6E-30 T 12-10-2018 UA74_23415 c57ea0e7367482223a27a63ea5c124f7 317 Gene3D G3DSA:2.60.120.200 61 286 1.7E-24 T 12-10-2018 UA74_23415 c57ea0e7367482223a27a63ea5c124f7 317 SUPERFAMILY SSF49899 53 283 3.03E-23 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UA74_17990 1307cec25f9c46e05c468f1d96947822 583 Gene3D G3DSA:3.50.50.60 12 107 2.6E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17990 1307cec25f9c46e05c468f1d96947822 583 Pfam PF01593 Flavin containing amine oxidoreductase 22 390 1.9E-13 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_17990 1307cec25f9c46e05c468f1d96947822 583 SUPERFAMILY SSF51905 10 531 4.02E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17990 1307cec25f9c46e05c468f1d96947822 583 Gene3D G3DSA:3.50.50.60 193 323 3.6E-18 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16005 fa56d036c613205340bfd81e288e1505 262 Pfam PF01063 Amino-transferase class IV 25 235 7.2E-33 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 UA74_16005 fa56d036c613205340bfd81e288e1505 262 SUPERFAMILY SSF56752 14 244 2.75E-39 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 UA74_16005 fa56d036c613205340bfd81e288e1505 262 Gene3D G3DSA:3.20.10.10 117 261 2.3E-21 T 12-10-2018 UA74_16005 fa56d036c613205340bfd81e288e1505 262 Gene3D G3DSA:3.30.470.10 16 111 6.4E-11 T 12-10-2018 UA74_07310 43960b67cd380d229a938ea78835882b 865 Pfam PF02927 Cellulase N-terminal ig-like domain 184 266 1.9E-22 T 12-10-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 UA74_07310 43960b67cd380d229a938ea78835882b 865 Pfam PF00553 Cellulose binding domain 764 864 2.8E-32 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_07310 43960b67cd380d229a938ea78835882b 865 Pfam PF00759 Glycosyl hydrolase family 9 277 742 5.9E-100 T 12-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_07310 43960b67cd380d229a938ea78835882b 865 SUPERFAMILY SSF81296 185 273 2.45E-21 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_07310 43960b67cd380d229a938ea78835882b 865 SUPERFAMILY SSF49785 33 172 2.38E-35 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_07310 43960b67cd380d229a938ea78835882b 865 SUPERFAMILY SSF49384 759 864 4.46E-32 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UA74_07310 43960b67cd380d229a938ea78835882b 865 Pfam PF02018 Carbohydrate binding domain 36 157 1.0E-15 T 12-10-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 UA74_07310 43960b67cd380d229a938ea78835882b 865 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 719 737 - T 12-10-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_07310 43960b67cd380d229a938ea78835882b 865 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 829 842 - T 12-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 UA74_07310 43960b67cd380d229a938ea78835882b 865 Gene3D G3DSA:1.50.10.10 275 750 4.7E-188 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_07310 43960b67cd380d229a938ea78835882b 865 SMART SM00637 764 864 1.3E-38 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_07310 43960b67cd380d229a938ea78835882b 865 Gene3D G3DSA:2.60.120.260 30 173 1.7E-32 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_07310 43960b67cd380d229a938ea78835882b 865 SUPERFAMILY SSF48208 276 748 4.47E-127 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_07310 43960b67cd380d229a938ea78835882b 865 Gene3D G3DSA:2.60.40.290 759 865 3.6E-33 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 UA74_07310 43960b67cd380d229a938ea78835882b 865 Gene3D G3DSA:2.60.40.10 184 273 9.0E-23 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_04240 30d043148b6c8efcd492f2e2e2cab64f 437 Gene3D G3DSA:3.20.20.60 16 421 4.8E-166 T 12-10-2018 UA74_04240 30d043148b6c8efcd492f2e2e2cab64f 437 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 18 261 7.7E-107 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 UA74_04240 30d043148b6c8efcd492f2e2e2cab64f 437 Pfam PF00463 Isocitrate lyase family 24 262 1.7E-56 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 UA74_04240 30d043148b6c8efcd492f2e2e2cab64f 437 Pfam PF00463 Isocitrate lyase family 263 433 7.7E-43 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 UA74_04240 30d043148b6c8efcd492f2e2e2cab64f 437 PIRSF PIRSF001362 10 437 2.7E-227 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 UA74_04240 30d043148b6c8efcd492f2e2e2cab64f 437 SUPERFAMILY SSF51621 17 437 4.17E-150 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UA74_04240 30d043148b6c8efcd492f2e2e2cab64f 437 ProSitePatterns PS00161 Isocitrate lyase signature. 199 204 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 UA74_00300 e8ce3f77a86efdbae2a595ea2a8cafe1 180 Pfam PF03413 Peptidase propeptide and YPEB domain 88 146 1.3E-14 T 12-10-2018 IPR025711 PepSY domain UA74_00300 e8ce3f77a86efdbae2a595ea2a8cafe1 180 Gene3D G3DSA:3.10.450.40 79 157 3.0E-17 T 12-10-2018 UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 PIRSF PIRSF001134 1 383 2.8E-122 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 Gene3D G3DSA:3.30.300.50 121 193 1.8E-7 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 346 360 2.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 322 345 2.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 303 320 2.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 282 302 2.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 222 236 2.3E-40 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 Gene3D G3DSA:3.30.300.50 42 119 1.7E-8 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 SUPERFAMILY SSF50494 201 377 7.08E-34 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 Pfam PF02983 Alpha-lytic protease prodomain 125 180 2.9E-12 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 Gene3D G3DSA:2.40.10.10 202 379 1.6E-71 T 12-10-2018 UA74_01965 b4fdb69c81ea38b58c515c998a6518ab 383 Gene3D G3DSA:2.40.10.10 270 368 1.6E-71 T 12-10-2018 UA74_27800 60f3234ed887b16cf745589ff8520f5c 382 Pfam PF00892 EamA-like transporter family 151 286 8.0E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_27800 60f3234ed887b16cf745589ff8520f5c 382 Pfam PF00892 EamA-like transporter family 12 140 1.5E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_27800 60f3234ed887b16cf745589ff8520f5c 382 SUPERFAMILY SSF103481 40 143 5.89E-10 T 12-10-2018 UA74_27800 60f3234ed887b16cf745589ff8520f5c 382 SUPERFAMILY SSF103481 196 291 3.14E-12 T 12-10-2018 UA74_27090 42810f1efcff6fcf0a6b84610c32f6c2 402 SUPERFAMILY SSF55347 142 317 5.07E-37 T 12-10-2018 UA74_27090 42810f1efcff6fcf0a6b84610c32f6c2 402 Gene3D G3DSA:3.30.360.10 141 395 2.8E-74 T 12-10-2018 UA74_27090 42810f1efcff6fcf0a6b84610c32f6c2 402 Gene3D G3DSA:3.40.50.720 3 140 1.0E-39 T 12-10-2018 UA74_27090 42810f1efcff6fcf0a6b84610c32f6c2 402 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 220 1.1E-11 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UA74_27090 42810f1efcff6fcf0a6b84610c32f6c2 402 SUPERFAMILY SSF51735 5 168 3.55E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_27090 42810f1efcff6fcf0a6b84610c32f6c2 402 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 126 1.1E-23 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_12020 599391a0663762b4f421351bb9930bb7 435 SUPERFAMILY SSF51905 186 369 6.09E-9 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_12020 599391a0663762b4f421351bb9930bb7 435 Gene3D G3DSA:3.50.50.60 2 423 5.2E-114 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_12020 599391a0663762b4f421351bb9930bb7 435 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 5 341 9.6E-103 T 12-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase UA74_12020 599391a0663762b4f421351bb9930bb7 435 SUPERFAMILY SSF51905 4 270 1.15E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 370 390 6.5E-29 T 12-10-2018 UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 58 78 6.5E-29 T 12-10-2018 UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 92 117 6.5E-29 T 12-10-2018 UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 16 36 6.5E-29 T 12-10-2018 UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 309 335 6.5E-29 T 12-10-2018 UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 344 363 6.5E-29 T 12-10-2018 UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 PRINTS PR00173 Glutamate-aspartate symporter signature 206 225 6.5E-29 T 12-10-2018 UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 Pfam PF00375 Sodium:dicarboxylate symporter family 18 415 2.2E-106 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 Gene3D G3DSA:1.10.3860.10 7 433 8.0E-116 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UA74_26935 53c354ef0233100ffe2eb333c9a8a9d1 476 SUPERFAMILY SSF118215 18 416 1.96E-96 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UA74_23135 6b1199cd218c5a9b55be758834c149d1 453 Gene3D G3DSA:2.120.10.30 126 229 1.4E-30 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_23135 6b1199cd218c5a9b55be758834c149d1 453 Gene3D G3DSA:2.120.10.30 230 339 1.1E-25 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_23135 6b1199cd218c5a9b55be758834c149d1 453 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 38 134 3.7E-6 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_23135 6b1199cd218c5a9b55be758834c149d1 453 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 164 338 7.1E-10 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_23135 6b1199cd218c5a9b55be758834c149d1 453 Gene3D G3DSA:2.120.10.30 73 125 2.3E-16 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_23135 6b1199cd218c5a9b55be758834c149d1 453 Gene3D G3DSA:2.120.10.30 12 72 1.4E-14 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_23135 6b1199cd218c5a9b55be758834c149d1 453 SUPERFAMILY SSF101898 33 283 1.67E-32 T 12-10-2018 UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 336 6.3E-93 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 SUPERFAMILY SSF46785 4 83 1.21E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 Gene3D G3DSA:3.30.450.40 105 335 1.4E-37 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 Pfam PF08220 DeoR-like helix-turn-helix domain 17 63 3.1E-5 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 Gene3D G3DSA:1.10.10.10 1 85 8.5E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 PIRSF PIRSF005485 1 340 6.9E-101 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 SUPERFAMILY SSF55781 72 338 5.3E-56 T 12-10-2018 UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 2 330 27.53 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 Gene3D G3DSA:3.30.390.60 128 229 1.4E-37 T 12-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily UA74_24515 d2d1e309b05d544560626acfe6f4520e 340 Pfam PF01628 HrcA protein C terminal domain 104 323 7.9E-61 T 12-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 UA74_07020 f52b0b336a71f6a8583ccf343ceedbe0 427 SUPERFAMILY SSF53383 12 424 3.16E-162 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_07020 f52b0b336a71f6a8583ccf343ceedbe0 427 Gene3D G3DSA:3.90.1150.10 16 395 2.2E-168 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_07020 f52b0b336a71f6a8583ccf343ceedbe0 427 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 12 424 49.398 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UA74_07020 f52b0b336a71f6a8583ccf343ceedbe0 427 PIRSF PIRSF000412 8 424 6.4E-158 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UA74_07020 f52b0b336a71f6a8583ccf343ceedbe0 427 Gene3D G3DSA:3.40.640.10 42 292 2.2E-168 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_07020 f52b0b336a71f6a8583ccf343ceedbe0 427 Pfam PF00464 Serine hydroxymethyltransferase 13 389 3.7E-155 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UA74_19940 00d940e0047c5c75c943d8a1ec2414f3 262 SUPERFAMILY SSF51735 6 222 3.45E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_19940 00d940e0047c5c75c943d8a1ec2414f3 262 Gene3D G3DSA:3.40.50.720 3 253 8.5E-43 T 12-10-2018 UA74_19940 00d940e0047c5c75c943d8a1ec2414f3 262 Pfam PF13460 NAD(P)H-binding 9 181 1.7E-18 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_15770 d92ca0759bd7a27995f905e009f82c95 207 Gene3D G3DSA:1.10.150.240 24 89 1.6E-38 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_15770 d92ca0759bd7a27995f905e009f82c95 207 Gene3D G3DSA:3.40.50.1000 13 192 1.6E-38 T 12-10-2018 IPR023214 HAD superfamily UA74_15770 d92ca0759bd7a27995f905e009f82c95 207 SUPERFAMILY SSF56784 11 198 7.26E-26 T 12-10-2018 IPR036412 HAD-like superfamily UA74_13475 4e4b083150707f7fa2999a64b08b834a 298 SUPERFAMILY SSF56300 26 287 4.86E-29 T 12-10-2018 UA74_13475 4e4b083150707f7fa2999a64b08b834a 298 Gene3D G3DSA:3.60.21.10 25 276 4.0E-11 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_13475 4e4b083150707f7fa2999a64b08b834a 298 Pfam PF00149 Calcineurin-like phosphoesterase 26 259 1.8E-15 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UA74_05290 18ac11862cf7c542bab11f68a9bb53ec 235 SUPERFAMILY SSF53474 6 233 2.23E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05290 18ac11862cf7c542bab11f68a9bb53ec 235 Pfam PF12697 Alpha/beta hydrolase family 7 230 9.7E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05290 18ac11862cf7c542bab11f68a9bb53ec 235 Gene3D G3DSA:3.40.50.1820 2 234 1.7E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_12305 85d072785edbd3f358cb055cf76714a9 211 Pfam PF00677 Lumazine binding domain 99 183 9.2E-27 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12305 85d072785edbd3f358cb055cf76714a9 211 Pfam PF00677 Lumazine binding domain 3 86 1.2E-22 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12305 85d072785edbd3f358cb055cf76714a9 211 SUPERFAMILY SSF63380 92 194 1.28E-33 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_12305 85d072785edbd3f358cb055cf76714a9 211 SUPERFAMILY SSF63380 2 87 1.53E-24 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_12305 85d072785edbd3f358cb055cf76714a9 211 Gene3D G3DSA:2.40.30.20 101 200 2.5E-36 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_12305 85d072785edbd3f358cb055cf76714a9 211 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 193 8.0E-64 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12305 85d072785edbd3f358cb055cf76714a9 211 PIRSF PIRSF000498 1 208 4.3E-73 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12305 85d072785edbd3f358cb055cf76714a9 211 Gene3D G3DSA:2.40.30.20 1 88 4.4E-27 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UA74_05905 d101f80f617ade26bffd33a20e75f523 655 SUPERFAMILY SSF89372 354 536 1.11E-14 T 12-10-2018 UA74_05905 d101f80f617ade26bffd33a20e75f523 655 Gene3D G3DSA:2.115.10.10 150 309 3.1E-25 T 12-10-2018 UA74_05905 d101f80f617ade26bffd33a20e75f523 655 Pfam PF14517 Tachylectin 67 288 2.0E-23 T 12-10-2018 IPR023294 Tachylectin 2 UA74_05905 d101f80f617ade26bffd33a20e75f523 655 SUPERFAMILY SSF50934 87 272 1.44E-14 T 12-10-2018 IPR036813 Tachylectin 2 superfamily UA74_07670 11ff2134670eb9d68581149c402bf67e 311 Gene3D G3DSA:3.40.50.1820 30 310 4.4E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07670 11ff2134670eb9d68581149c402bf67e 311 Pfam PF12697 Alpha/beta hydrolase family 34 304 2.8E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_07670 11ff2134670eb9d68581149c402bf67e 311 SUPERFAMILY SSF53474 28 307 1.23E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 SMART SM00448 2 115 5.8E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 SUPERFAMILY SSF52172 3 132 5.55E-32 T 12-10-2018 IPR011006 CheY-like superfamily UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 SMART SM00421 142 199 2.6E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 5.5E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 SUPERFAMILY SSF46894 133 205 1.16E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 Gene3D G3DSA:3.40.50.12740 2 205 1.1E-65 T 12-10-2018 UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 9.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 9.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 9.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_24275 d6bb24d3bba0f4d922757d9d7ab45228 211 Pfam PF00072 Response regulator receiver domain 5 115 3.3E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_19470 c0d9f8e093e890cb930bfaa87316d284 229 SUPERFAMILY SSF52788 98 221 3.66E-36 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily UA74_19470 c0d9f8e093e890cb930bfaa87316d284 229 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 100 221 4.1E-24 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UA74_19470 c0d9f8e093e890cb930bfaa87316d284 229 SMART SM00226 98 223 4.3E-42 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UA74_19470 c0d9f8e093e890cb930bfaa87316d284 229 Gene3D G3DSA:1.10.8.1060 22 95 2.6E-22 T 12-10-2018 UA74_19470 c0d9f8e093e890cb930bfaa87316d284 229 Gene3D G3DSA:3.40.50.2300 96 228 2.3E-52 T 12-10-2018 UA74_15050 0a0a209b140a83f4702fefd83b0b7242 276 SUPERFAMILY SSF141571 60 269 2.9E-19 T 12-10-2018 UA74_15050 0a0a209b140a83f4702fefd83b0b7242 276 Pfam PF00805 Pentapeptide repeats (8 copies) 192 225 2.8E-10 T 12-10-2018 IPR001646 Pentapeptide repeat UA74_15050 0a0a209b140a83f4702fefd83b0b7242 276 Gene3D G3DSA:2.160.20.100 175 266 2.1E-18 T 12-10-2018 UA74_29435 1bcdf236441490f9d46dbe9f399aba65 214 Pfam PF07510 Protein of unknown function (DUF1524) 110 208 2.7E-12 T 12-10-2018 IPR011089 Domain of unknown function DUF1524 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 Gene3D G3DSA:3.20.20.120 128 426 9.2E-134 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_03730 e19f7f8a6827ba8270174224187e5458 428 ProSitePatterns PS00164 Enolase signature. 332 345 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 SMART SM01192 139 423 1.6E-216 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 Hamap MF_00318 Enolase [eno]. 2 409 45.533 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 PIRSF PIRSF001400 1 422 3.2E-192 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 418 9.4E-132 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 SUPERFAMILY SSF51604 138 421 7.34E-128 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_03730 e19f7f8a6827ba8270174224187e5458 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 6.3E-206 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 Pfam PF03952 Enolase, N-terminal domain 4 134 1.5E-56 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 Gene3D G3DSA:3.30.390.10 1 127 3.0E-53 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_03730 e19f7f8a6827ba8270174224187e5458 428 SUPERFAMILY SSF54826 4 136 1.7E-51 T 12-10-2018 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 361 378 2.6E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 161 174 2.6E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 309 320 2.6E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 332 346 2.6E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 107 123 2.6E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 PRINTS PR00148 Enolase signature 37 51 2.6E-48 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_03730 e19f7f8a6827ba8270174224187e5458 428 SMART SM01193 4 134 5.7E-86 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UA74_02715 d11715474e7248e51c6cca0628f9c1fd 612 SMART SM00331 15 247 4.9E-27 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_02715 d11715474e7248e51c6cca0628f9c1fd 612 SMART SM00332 6 245 1.6E-21 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_02715 d11715474e7248e51c6cca0628f9c1fd 612 Gene3D G3DSA:3.60.40.10 4 248 1.1E-61 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_02715 d11715474e7248e51c6cca0628f9c1fd 612 Pfam PF13672 Protein phosphatase 2C 20 208 2.3E-12 T 12-10-2018 UA74_02715 d11715474e7248e51c6cca0628f9c1fd 612 SUPERFAMILY SSF81606 8 246 1.29E-59 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_28000 e381677f4ecca35e3e51517d6fe6ffac 276 SUPERFAMILY SSF53474 15 242 2.63E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_28000 e381677f4ecca35e3e51517d6fe6ffac 276 Pfam PF12740 Chlorophyllase enzyme 31 148 1.6E-7 T 12-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 UA74_28000 e381677f4ecca35e3e51517d6fe6ffac 276 Gene3D G3DSA:3.40.50.1820 4 266 7.7E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17630 536bbb0062724bd9be17a51f3bb1e744 189 Gene3D G3DSA:3.40.430.10 1 187 3.3E-35 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_17630 536bbb0062724bd9be17a51f3bb1e744 189 Pfam PF01872 RibD C-terminal domain 4 175 7.5E-21 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_17630 536bbb0062724bd9be17a51f3bb1e744 189 SUPERFAMILY SSF53597 3 178 1.96E-22 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_01010 b6b6ebd964c4561018700141dd397bcf 323 SUPERFAMILY SSF75005 103 287 1.57E-22 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_01010 b6b6ebd964c4561018700141dd397bcf 323 Gene3D G3DSA:2.115.10.20 96 307 2.0E-15 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_01010 b6b6ebd964c4561018700141dd397bcf 323 Pfam PF04616 Glycosyl hydrolases family 43 104 235 1.8E-9 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_18075 53492e8a35a3c250513805494535046d 260 Pfam PF12697 Alpha/beta hydrolase family 47 241 4.3E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_18075 53492e8a35a3c250513805494535046d 260 Gene3D G3DSA:3.40.50.1820 1 249 1.5E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18075 53492e8a35a3c250513805494535046d 260 SUPERFAMILY SSF53474 4 253 2.1E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 SUPERFAMILY SSF52540 314 559 1.54E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 Pfam PF00005 ABC transporter 31 189 2.6E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 SUPERFAMILY SSF52540 10 260 2.66E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 SMART SM00382 39 238 1.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 SMART SM00382 345 537 7.9E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 Gene3D G3DSA:3.40.50.300 8 311 6.6E-85 T 12-10-2018 UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 Gene3D G3DSA:3.40.50.300 312 567 2.7E-78 T 12-10-2018 UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 282 7.7E-4 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 539 564 0.021 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_20140 5d3945e35c7ccb1123e7414a108a9033 570 Pfam PF00005 ABC transporter 337 487 8.2E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_29810 6bc89452d341eae693de60b794700b83 541 Pfam PF00350 Dynamin family 41 145 4.3E-10 T 12-10-2018 IPR022812 Dynamin superfamily UA74_29810 6bc89452d341eae693de60b794700b83 541 SUPERFAMILY SSF52540 33 153 3.6E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_17405 a433ccf78fef9082b58eb704c8efa115 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 65 1.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_17405 a433ccf78fef9082b58eb704c8efa115 217 Gene3D G3DSA:1.10.357.10 15 209 8.1E-33 T 12-10-2018 UA74_17405 a433ccf78fef9082b58eb704c8efa115 217 SUPERFAMILY SSF46689 5 86 5.64E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 SUPERFAMILY SSF56235 2 225 1.8E-60 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 Pfam PF01380 SIS domain 283 407 3.8E-32 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 Pfam PF01380 SIS domain 455 584 3.3E-21 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 Pfam PF13522 Glutamine amidotransferase domain 50 187 7.5E-22 T 12-10-2018 UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 Gene3D G3DSA:3.60.20.10 1 234 5.0E-67 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 Gene3D G3DSA:3.40.50.10490 244 605 3.9E-138 T 12-10-2018 UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 606 38.288 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 Gene3D G3DSA:3.40.50.10490 440 591 3.9E-138 T 12-10-2018 UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 SUPERFAMILY SSF53697 239 606 1.02E-105 T 12-10-2018 UA74_27995 00e44acac8e80ffc546d5d5d2803faa1 606 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 1 606 9.7E-239 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 UA74_09200 eed82a06fd1b376bd7cf0a117fe1dd8c 397 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 65 388 3.0E-136 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 UA74_09200 eed82a06fd1b376bd7cf0a117fe1dd8c 397 Pfam PF00296 Luciferase-like monooxygenase 77 365 2.8E-37 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_09200 eed82a06fd1b376bd7cf0a117fe1dd8c 397 Gene3D G3DSA:3.20.20.30 60 394 1.8E-112 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_09200 eed82a06fd1b376bd7cf0a117fe1dd8c 397 SUPERFAMILY SSF51679 64 388 6.28E-82 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_00805 732a4f7f6ad3c9c3a8f9a8ed51a0d436 235 SUPERFAMILY SSF53474 4 234 1.29E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_00805 732a4f7f6ad3c9c3a8f9a8ed51a0d436 235 Pfam PF01738 Dienelactone hydrolase family 18 233 1.5E-24 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 UA74_00805 732a4f7f6ad3c9c3a8f9a8ed51a0d436 235 Gene3D G3DSA:3.40.50.1820 6 232 2.7E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_00665 247735f568a2dba8baf1889bf591bf45 294 SUPERFAMILY SSF53448 3 236 6.49E-31 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_00665 247735f568a2dba8baf1889bf591bf45 294 Pfam PF00535 Glycosyl transferase family 2 5 123 1.7E-15 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_00665 247735f568a2dba8baf1889bf591bf45 294 Gene3D G3DSA:3.90.550.10 2 254 5.8E-27 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 Gene3D G3DSA:3.50.30.20 5 153 3.1E-55 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 SMART SM01097 5 135 3.2E-82 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 Pfam PF00117 Glutamine amidotransferase class-I 187 367 1.2E-36 T 12-10-2018 IPR017926 Glutamine amidotransferase UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 Gene3D G3DSA:3.40.50.880 155 372 2.2E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 270 287 5.3E-32 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 183 197 5.3E-32 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 222 236 5.3E-32 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 295 306 5.3E-32 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 253 269 5.3E-32 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 5 373 44.412 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 SUPERFAMILY SSF52317 156 370 9.94E-51 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 253 264 1.9E-11 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 225 234 1.9E-11 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00096 Glutamine amidotransferase superfamily signature 344 357 1.9E-11 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 7 133 4.0E-51 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 SUPERFAMILY SSF52021 6 137 2.88E-53 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 7 370 9.3E-132 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00097 Anthranilate synthase component II signature 344 357 2.9E-6 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00097 Anthranilate synthase component II signature 253 264 2.9E-6 T 12-10-2018 UA74_12205 42c49338a25d4abdf10ceeffecc3e873 379 PRINTS PR00097 Anthranilate synthase component II signature 225 234 2.9E-6 T 12-10-2018 UA74_26525 bf7474ce89058293ad55e72a2d518f25 246 SUPERFAMILY SSF53271 51 223 5.25E-13 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_26525 bf7474ce89058293ad55e72a2d518f25 246 Gene3D G3DSA:3.40.50.2020 72 238 3.3E-11 T 12-10-2018 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 493 526 39.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 655 688 0.89 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 533 566 6.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 575 608 110.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 SMART SM00028 615 648 400.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 SUPERFAMILY SSF48452 494 684 1.14E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 Gene3D G3DSA:3.40.50.300 43 203 9.8E-22 T 12-10-2018 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 Gene3D G3DSA:1.25.40.10 461 604 6.9E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 PRINTS PR00364 Disease resistance protein signature 157 171 3.1E-8 T 12-10-2018 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 PRINTS PR00364 Disease resistance protein signature 244 258 3.1E-8 T 12-10-2018 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 PRINTS PR00364 Disease resistance protein signature 80 95 3.1E-8 T 12-10-2018 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 Gene3D G3DSA:1.25.40.10 606 701 2.4E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 SUPERFAMILY SSF52540 51 309 2.78E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_23070 39334908a40ecd4d19700e6171bc291a 729 Pfam PF00931 NB-ARC domain 71 310 2.8E-13 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_23070 39334908a40ecd4d19700e6171bc291a 729 Pfam PF13424 Tetratricopeptide repeat 534 601 9.5E-8 T 12-10-2018 UA74_16540 a0f4e3c7ad2d7225236a3c014b4125db 248 Pfam PF01061 ABC-2 type transporter 2 212 2.3E-31 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_16540 a0f4e3c7ad2d7225236a3c014b4125db 248 PRINTS PR00164 ABC-2 type transport system membrane protein signature 191 210 8.4E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_16540 a0f4e3c7ad2d7225236a3c014b4125db 248 PRINTS PR00164 ABC-2 type transport system membrane protein signature 17 38 8.4E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_16540 a0f4e3c7ad2d7225236a3c014b4125db 248 PRINTS PR00164 ABC-2 type transport system membrane protein signature 171 190 8.4E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_16540 a0f4e3c7ad2d7225236a3c014b4125db 248 PIRSF PIRSF006648 1 248 2.5E-57 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 626 727 3.5E-22 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 100 728 43.874 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 SUPERFAMILY SSF81296 18 113 1.61E-18 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 SUPERFAMILY SSF81296 116 223 3.67E-30 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 SMART SM00642 253 594 5.3E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 SUPERFAMILY SSF51445 177 614 8.9E-114 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 PIRSF PIRSF000463 10 729 5.5E-281 T 12-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 Gene3D G3DSA:3.20.20.80 226 620 2.4E-173 T 12-10-2018 UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 Pfam PF00128 Alpha amylase, catalytic domain 274 342 1.9E-9 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 Gene3D G3DSA:2.60.40.1180 621 728 1.7E-38 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 SUPERFAMILY SSF51011 622 728 6.76E-31 T 12-10-2018 UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 124 210 3.3E-20 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 Gene3D G3DSA:2.60.40.10 7 225 6.3E-72 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_07255 553edc381a03f4cb7cb1bcd4d6bb368e 729 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 108 725 4.3E-275 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 UA74_21865 a4e84e5b80487e64d8216d3556503d55 382 Gene3D G3DSA:3.30.360.10 144 351 5.7E-82 T 12-10-2018 UA74_21865 a4e84e5b80487e64d8216d3556503d55 382 SUPERFAMILY SSF51735 1 173 5.65E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_21865 a4e84e5b80487e64d8216d3556503d55 382 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 108 1.1E-24 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_21865 a4e84e5b80487e64d8216d3556503d55 382 Gene3D G3DSA:3.40.50.720 1 328 5.7E-82 T 12-10-2018 UA74_21865 a4e84e5b80487e64d8216d3556503d55 382 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 151 257 1.2E-11 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UA74_21865 a4e84e5b80487e64d8216d3556503d55 382 SUPERFAMILY SSF55347 149 283 3.6E-24 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 138 347 2.5E-27 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_25570 726786be75d31a51538187a238e45ffb 712 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 466 631 7.0E-39 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UA74_25570 726786be75d31a51538187a238e45ffb 712 SUPERFAMILY SSF81653 138 227 1.57E-19 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 UA74_25570 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 325 339 5.0E-26 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 470 481 5.0E-26 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 174 188 5.0E-26 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 568 580 5.0E-26 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 564 5.0E-26 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 492 502 5.0E-26 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 Pfam PF00122 E1-E2 ATPase 135 303 1.0E-32 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 Pfam PF00702 haloacid dehalogenase-like hydrolase 323 559 1.7E-32 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 Gene3D G3DSA:1.20.1110.10 590 634 6.0E-23 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 327 333 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UA74_25570 726786be75d31a51538187a238e45ffb 712 SUPERFAMILY SSF81665 45 319 1.96E-12 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UA74_25570 726786be75d31a51538187a238e45ffb 712 SUPERFAMILY SSF56784 313 588 3.92E-38 T 12-10-2018 IPR036412 HAD-like superfamily UA74_25570 726786be75d31a51538187a238e45ffb 712 Gene3D G3DSA:3.40.50.1000 524 589 6.0E-23 T 12-10-2018 IPR023214 HAD superfamily UA74_25570 726786be75d31a51538187a238e45ffb 712 Gene3D G3DSA:1.20.1110.10 227 339 1.4E-6 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 Gene3D G3DSA:3.40.50.1000 476 523 1.8E-5 T 12-10-2018 IPR023214 HAD superfamily UA74_25570 726786be75d31a51538187a238e45ffb 712 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 24 705 1.4E-288 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 UA74_25570 726786be75d31a51538187a238e45ffb 712 Gene3D G3DSA:2.70.150.20 122 226 3.0E-21 T 12-10-2018 UA74_25570 726786be75d31a51538187a238e45ffb 712 Gene3D G3DSA:3.40.1110.10 340 475 1.6E-39 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UA74_25570 726786be75d31a51538187a238e45ffb 712 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 24 709 39.114 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 UA74_19680 b5294e64d3c4b7a989fcd0c6f63cfec0 378 SUPERFAMILY SSF56601 11 373 9.01E-57 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_19680 b5294e64d3c4b7a989fcd0c6f63cfec0 378 Pfam PF00144 Beta-lactamase 30 365 1.6E-51 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_19680 b5294e64d3c4b7a989fcd0c6f63cfec0 378 Gene3D G3DSA:3.40.710.30 5 378 6.4E-113 T 12-10-2018 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 392 402 2.8E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 255 272 2.8E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 357 381 2.8E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 275 301 2.8E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00463 E-class P450 group I signature 402 425 2.8E-20 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 SUPERFAMILY SSF48264 4 453 3.27E-112 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00385 P450 superfamily signature 393 402 9.3E-14 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00385 P450 superfamily signature 318 329 9.3E-14 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00385 P450 superfamily signature 266 283 9.3E-14 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 PRINTS PR00385 P450 superfamily signature 402 413 9.3E-14 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 Gene3D G3DSA:1.10.630.10 4 453 3.4E-125 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28660 2b7d5a918143e81c49cb5075c0236095 453 Pfam PF00067 Cytochrome P450 8 431 1.5E-86 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_30045 8acb1d1f89161ccbbab9b635a13ede56 276 Pfam PF01061 ABC-2 type transporter 26 239 3.8E-25 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_30045 8acb1d1f89161ccbbab9b635a13ede56 276 PIRSF PIRSF006648 1 275 5.4E-75 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_05325 b177f76ab84a5b37f7b25099492763d9 397 Pfam PF07730 Histidine kinase 187 251 3.1E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_05325 b177f76ab84a5b37f7b25099492763d9 397 Gene3D G3DSA:3.30.565.10 261 385 2.2E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_05325 b177f76ab84a5b37f7b25099492763d9 397 SUPERFAMILY SSF55874 273 384 7.26E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_10330 af4d9fb3406b1efe1d5676d0e65b7339 140 Gene3D G3DSA:2.60.120.10 26 137 2.6E-29 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_10330 af4d9fb3406b1efe1d5676d0e65b7339 140 PIRSF PIRSF029883 31 139 7.7E-25 T 12-10-2018 IPR025499 Pectin degradation protein KdgF UA74_10330 af4d9fb3406b1efe1d5676d0e65b7339 140 SUPERFAMILY SSF51182 43 132 3.96E-23 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_10330 af4d9fb3406b1efe1d5676d0e65b7339 140 Pfam PF07883 Cupin domain 62 117 1.8E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel UA74_10915 e2e96a8dccd62f87fe73b1fb5130f37f 343 SUPERFAMILY SSF46785 15 94 4.08E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_10915 e2e96a8dccd62f87fe73b1fb5130f37f 343 Pfam PF16864 Dimerisation domain 17 95 2.0E-13 T 12-10-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain UA74_10915 e2e96a8dccd62f87fe73b1fb5130f37f 343 Gene3D G3DSA:3.40.50.150 96 343 3.1E-49 T 12-10-2018 UA74_10915 e2e96a8dccd62f87fe73b1fb5130f37f 343 SUPERFAMILY SSF53335 96 334 3.52E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_10915 e2e96a8dccd62f87fe73b1fb5130f37f 343 Gene3D G3DSA:1.10.10.10 8 88 7.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10915 e2e96a8dccd62f87fe73b1fb5130f37f 343 PIRSF PIRSF005739 33 338 3.6E-22 T 12-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 UA74_10915 e2e96a8dccd62f87fe73b1fb5130f37f 343 Pfam PF00891 O-methyltransferase 104 325 6.9E-32 T 12-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 UA74_11190 259761f9356156cb893416374aa79285 1489 Pfam PF11721 Di-glucose binding within endoplasmic reticulum 1331 1468 2.1E-19 T 12-10-2018 IPR021720 Malectin domain Reactome: R-HSA-532668|Reactome: R-HSA-6798695 UA74_11190 259761f9356156cb893416374aa79285 1489 Pfam PF00082 Subtilase family 200 471 3.4E-38 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_11190 259761f9356156cb893416374aa79285 1489 SUPERFAMILY SSF49464 863 943 1.2E-10 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily UA74_11190 259761f9356156cb893416374aa79285 1489 Gene3D G3DSA:2.60.120.430 1326 1485 3.0E-19 T 12-10-2018 UA74_11190 259761f9356156cb893416374aa79285 1489 Pfam PF13620 Carboxypeptidase regulatory-like domain 863 942 9.8E-9 T 12-10-2018 UA74_11190 259761f9356156cb893416374aa79285 1489 Pfam PF13620 Carboxypeptidase regulatory-like domain 508 584 4.8E-12 T 12-10-2018 UA74_11190 259761f9356156cb893416374aa79285 1489 Pfam PF13620 Carboxypeptidase regulatory-like domain 590 666 1.4E-9 T 12-10-2018 UA74_11190 259761f9356156cb893416374aa79285 1489 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 258 268 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UA74_11190 259761f9356156cb893416374aa79285 1489 Gene3D G3DSA:2.60.40.1120 591 667 1.8E-7 T 12-10-2018 UA74_11190 259761f9356156cb893416374aa79285 1489 Gene3D G3DSA:2.60.40.1120 508 585 2.6E-15 T 12-10-2018 UA74_11190 259761f9356156cb893416374aa79285 1489 SUPERFAMILY SSF49464 508 583 1.14E-12 T 12-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily UA74_11190 259761f9356156cb893416374aa79285 1489 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 431 441 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_11190 259761f9356156cb893416374aa79285 1489 SUPERFAMILY SSF49785 1337 1488 2.47E-9 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_11190 259761f9356156cb893416374aa79285 1489 SUPERFAMILY SSF49452 585 666 5.69E-10 T 12-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 UA74_11190 259761f9356156cb893416374aa79285 1489 SUPERFAMILY SSF63829 1093 1256 1.11E-8 T 12-10-2018 UA74_11190 259761f9356156cb893416374aa79285 1489 Gene3D G3DSA:2.60.40.1120 863 949 3.2E-10 T 12-10-2018 UA74_11190 259761f9356156cb893416374aa79285 1489 SUPERFAMILY SSF52743 181 498 2.36E-58 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_11190 259761f9356156cb893416374aa79285 1489 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 219 1.2E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_11190 259761f9356156cb893416374aa79285 1489 PRINTS PR00723 Subtilisin serine protease family (S8) signature 254 267 1.2E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_11190 259761f9356156cb893416374aa79285 1489 PRINTS PR00723 Subtilisin serine protease family (S8) signature 430 446 1.2E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_11190 259761f9356156cb893416374aa79285 1489 Gene3D G3DSA:3.40.50.200 173 500 8.1E-65 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_00915 73b4e182141e9402236712a55aaec71d 334 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 35 325 1.8E-102 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 UA74_00915 73b4e182141e9402236712a55aaec71d 334 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 8 329 1.5E-108 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 UA74_00915 73b4e182141e9402236712a55aaec71d 334 Gene3D G3DSA:3.40.718.10 1 331 1.6E-134 T 12-10-2018 UA74_00915 73b4e182141e9402236712a55aaec71d 334 SUPERFAMILY SSF53659 6 329 1.52E-104 T 12-10-2018 UA74_26965 7ec0cdceb150005594f2776e9a415ecd 275 Pfam PF14011 EspG family 16 258 1.6E-59 T 12-10-2018 IPR025734 EspG family UA74_09455 91602c2b0d9589905a8174b338d5953a 72 TIGRFAM TIGR03898 lanti_MRSA_kill: type 2 lantibiotic, mersacidin/lichenicidin family 3 45 6.5E-11 T 12-10-2018 IPR027635 Type 2 lantibiotic, leader peptide domain GO:0042742 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 Gene3D G3DSA:3.40.50.720 187 419 2.3E-42 T 12-10-2018 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 Gene3D G3DSA:3.40.50.10860 40 156 1.6E-26 T 12-10-2018 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 97 110 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 SUPERFAMILY SSF53223 37 160 6.72E-29 T 12-10-2018 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 SMART SM00839 192 419 4.2E-41 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 PIRSF PIRSF000185 23 423 5.6E-80 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 SUPERFAMILY SSF51735 187 414 4.72E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 220 240 8.1E-7 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 89 103 8.1E-7 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 187 354 2.4E-32 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UA74_06910 67672b2281be545a13a3ea1225d18b1f 428 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 43 150 1.3E-18 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UA74_20085 8f6ddfaa2ea6612ce55b0e887ea424df 368 Gene3D G3DSA:3.40.50.1820 1 365 3.1E-136 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20085 8f6ddfaa2ea6612ce55b0e887ea424df 368 SUPERFAMILY SSF53474 2 357 1.54E-99 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20085 8f6ddfaa2ea6612ce55b0e887ea424df 368 PIRSF PIRSF001112 1 360 1.3E-108 T 12-10-2018 IPR016292 Epoxide hydrolase GO:0033961 Reactome: R-HSA-211945 UA74_20085 8f6ddfaa2ea6612ce55b0e887ea424df 368 Pfam PF06441 Epoxide hydrolase N terminus 2 107 1.5E-38 T 12-10-2018 IPR010497 Epoxide hydrolase, N-terminal Reactome: R-HSA-211945 UA74_20085 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 162 175 1.2E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_20085 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 176 189 1.2E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_20085 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 301 317 1.2E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_20085 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 332 354 1.2E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_20085 8f6ddfaa2ea6612ce55b0e887ea424df 368 PRINTS PR00412 Epoxide hydrolase signature 98 116 1.2E-9 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_03655 dd2b67f12e602da122158e61a0450d07 249 ProSitePatterns PS01081 TetR-type HTH domain signature. 72 102 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_03655 dd2b67f12e602da122158e61a0450d07 249 Gene3D G3DSA:1.10.357.10 45 239 2.8E-50 T 12-10-2018 UA74_03655 dd2b67f12e602da122158e61a0450d07 249 SUPERFAMILY SSF46689 46 126 5.13E-21 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_03655 dd2b67f12e602da122158e61a0450d07 249 Pfam PF00440 Bacterial regulatory proteins, tetR family 60 104 7.0E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03655 dd2b67f12e602da122158e61a0450d07 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 60 73 9.5E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03655 dd2b67f12e602da122158e61a0450d07 249 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 81 104 9.5E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03655 dd2b67f12e602da122158e61a0450d07 249 SUPERFAMILY SSF48498 127 236 3.71E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_00625 b646384528906384bae0d1ab0212016d 189 Gene3D G3DSA:2.60.120.10 83 184 4.3E-14 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_00625 b646384528906384bae0d1ab0212016d 189 SMART SM00530 16 71 9.1E-16 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_00625 b646384528906384bae0d1ab0212016d 189 SUPERFAMILY SSF47413 10 77 5.36E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_00625 b646384528906384bae0d1ab0212016d 189 SUPERFAMILY SSF51182 56 183 5.24E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_00625 b646384528906384bae0d1ab0212016d 189 Pfam PF07883 Cupin domain 116 183 1.4E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel UA74_00625 b646384528906384bae0d1ab0212016d 189 Pfam PF13560 Helix-turn-helix domain 13 71 4.5E-16 T 12-10-2018 UA74_00625 b646384528906384bae0d1ab0212016d 189 Gene3D G3DSA:1.10.260.40 11 82 1.0E-19 T 12-10-2018 UA74_04300 82f1273218b7a3dc864083039c3d0bba 341 Gene3D G3DSA:3.40.50.2000 146 210 1.2E-11 T 12-10-2018 UA74_04300 82f1273218b7a3dc864083039c3d0bba 341 SUPERFAMILY SSF53756 120 330 5.1E-16 T 12-10-2018 UA74_04300 82f1273218b7a3dc864083039c3d0bba 341 Gene3D G3DSA:3.40.50.2000 211 330 1.2E-11 T 12-10-2018 UA74_25690 9d9ac4820bd47fed0e3f55f3f7fbf942 306 Gene3D G3DSA:3.40.50.1820 22 306 3.7E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_25690 9d9ac4820bd47fed0e3f55f3f7fbf942 306 Pfam PF07859 alpha/beta hydrolase fold 73 280 1.6E-51 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 UA74_25690 9d9ac4820bd47fed0e3f55f3f7fbf942 306 SUPERFAMILY SSF53474 34 301 3.57E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16870 a739deb0107ba37f8160a13e02c5cc13 208 SUPERFAMILY SSF48498 87 194 4.45E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_16870 a739deb0107ba37f8160a13e02c5cc13 208 SUPERFAMILY SSF46689 10 85 5.64E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_16870 a739deb0107ba37f8160a13e02c5cc13 208 Gene3D G3DSA:1.10.357.10 1 199 5.3E-50 T 12-10-2018 UA74_16870 a739deb0107ba37f8160a13e02c5cc13 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 2.5E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_16870 a739deb0107ba37f8160a13e02c5cc13 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_16870 a739deb0107ba37f8160a13e02c5cc13 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.5E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06630 9c4c0a644b2d82ee968a07cb31adc567 231 SUPERFAMILY SSF52317 6 188 2.29E-53 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_06630 9c4c0a644b2d82ee968a07cb31adc567 231 Pfam PF01965 DJ-1/PfpI family 8 167 4.5E-31 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UA74_06630 9c4c0a644b2d82ee968a07cb31adc567 231 Gene3D G3DSA:3.40.50.880 2 228 4.7E-75 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_21330 194e5b443b3fb345fea06eb3a42fafed 280 SUPERFAMILY SSF63380 10 139 8.7E-14 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_21330 194e5b443b3fb345fea06eb3a42fafed 280 Pfam PF08021 Siderophore-interacting FAD-binding domain 21 136 5.6E-34 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting UA74_21330 194e5b443b3fb345fea06eb3a42fafed 280 Gene3D G3DSA:2.40.30.10 3 137 5.2E-46 T 12-10-2018 UA74_21330 194e5b443b3fb345fea06eb3a42fafed 280 Pfam PF04954 Siderophore-interacting protein 144 264 9.7E-37 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain UA74_21330 194e5b443b3fb345fea06eb3a42fafed 280 Gene3D G3DSA:3.40.50.80 140 278 7.5E-45 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 SUPERFAMILY SSF56672 16 253 5.43E-68 T 12-10-2018 UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 Pfam PF11798 IMS family HHH motif 183 212 2.1E-5 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 Pfam PF00817 impB/mucB/samB family 22 169 2.6E-37 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 Gene3D G3DSA:3.30.1490.100 256 362 4.1E-22 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 Gene3D G3DSA:3.30.70.270 87 180 6.2E-25 T 12-10-2018 UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 Gene3D G3DSA:1.10.150.20 185 252 1.9E-17 T 12-10-2018 UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 Pfam PF11799 impB/mucB/samB family C-terminal domain 249 361 9.3E-21 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 SUPERFAMILY SSF100879 255 355 9.89E-23 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 Gene3D G3DSA:2.30.40.20 27 86 2.4E-21 T 12-10-2018 UA74_07210 85b5670f9b7b7debfc0009c6b74ab716 536 Hamap MF_01113 DNA polymerase IV [dinB]. 16 364 33.051 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 UA74_13160 607cdb8fd4378c57b8ea418fa51f3d82 288 PIRSF PIRSF017393 20 288 7.6E-98 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_13160 607cdb8fd4378c57b8ea418fa51f3d82 288 Gene3D G3DSA:3.40.50.150 21 288 1.2E-103 T 12-10-2018 UA74_13160 607cdb8fd4378c57b8ea418fa51f3d82 288 SUPERFAMILY SSF53335 31 269 2.04E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_13160 607cdb8fd4378c57b8ea418fa51f3d82 288 Pfam PF04672 S-adenosyl methyltransferase 30 287 4.2E-92 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_20850 86732e9490fa3960127fcbd0f29eed76 210 SUPERFAMILY SSF46894 141 210 1.5E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_20850 86732e9490fa3960127fcbd0f29eed76 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_20850 86732e9490fa3960127fcbd0f29eed76 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_20850 86732e9490fa3960127fcbd0f29eed76 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.3E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_20850 86732e9490fa3960127fcbd0f29eed76 210 SMART SM00421 147 204 7.3E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_20850 86732e9490fa3960127fcbd0f29eed76 210 Gene3D G3DSA:1.10.10.10 94 210 3.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20850 86732e9490fa3960127fcbd0f29eed76 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 3.8E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_20670 567a06cc254ce1e58d3741b2340747cb 258 SUPERFAMILY SSF52266 49 234 3.0E-14 T 12-10-2018 UA74_20670 567a06cc254ce1e58d3741b2340747cb 258 Gene3D G3DSA:3.40.50.1110 21 230 1.5E-14 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_04745 f7f317ce39cd72f4ce854a30f1f69979 264 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 6 259 2.1E-79 T 12-10-2018 IPR013402 Conserved hypothetical protein CHP02569 UA74_04745 f7f317ce39cd72f4ce854a30f1f69979 264 SUPERFAMILY SSF56112 35 199 2.04E-11 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_03010 25efde8ecf05ba8f4bab85aebfe2421f 61 Gene3D G3DSA:4.10.830.10 1 61 2.7E-31 T 12-10-2018 UA74_03010 25efde8ecf05ba8f4bab85aebfe2421f 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 12-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03010 25efde8ecf05ba8f4bab85aebfe2421f 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.4E-24 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_03010 25efde8ecf05ba8f4bab85aebfe2421f 61 SUPERFAMILY SSF57716 4 61 5.2E-22 T 12-10-2018 UA74_03010 25efde8ecf05ba8f4bab85aebfe2421f 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.208 T 12-10-2018 IPR023053 Ribosomal protein S14, type Z UA74_12870 313a31610c19aae59b0a601aa6a0a1b5 175 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_12870 313a31610c19aae59b0a601aa6a0a1b5 175 Gene3D G3DSA:3.90.79.10 3 169 1.9E-36 T 12-10-2018 UA74_12870 313a31610c19aae59b0a601aa6a0a1b5 175 SUPERFAMILY SSF55811 6 167 1.9E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_12870 313a31610c19aae59b0a601aa6a0a1b5 175 Pfam PF00293 NUDIX domain 32 156 1.2E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_12870 313a31610c19aae59b0a601aa6a0a1b5 175 PIRSF PIRSF017340 1 171 2.5E-51 T 12-10-2018 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 UA74_16100 dbf652c110cbbc2a1c7f8e396d81b155 227 Pfam PF08666 SAF domain 67 128 2.4E-4 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UA74_12360 19d9fd7c08ed07ba32612166bf504621 262 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 4 255 59.114 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12360 19d9fd7c08ed07ba32612166bf504621 262 Gene3D G3DSA:3.20.20.70 2 262 7.6E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_12360 19d9fd7c08ed07ba32612166bf504621 262 ProSitePatterns PS00171 Triosephosphate isomerase active site. 171 181 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12360 19d9fd7c08ed07ba32612166bf504621 262 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 7 247 3.7E-57 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12360 19d9fd7c08ed07ba32612166bf504621 262 SUPERFAMILY SSF51351 3 255 4.71E-90 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_12360 19d9fd7c08ed07ba32612166bf504621 262 Pfam PF00121 Triosephosphate isomerase 7 253 8.7E-88 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_23400 3327e126df192a4bec3a056145d4d3d4 234 SUPERFAMILY SSF81606 15 233 1.57E-13 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_23400 3327e126df192a4bec3a056145d4d3d4 234 Gene3D G3DSA:3.60.40.10 9 234 2.0E-8 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_23400 3327e126df192a4bec3a056145d4d3d4 234 Pfam PF13672 Protein phosphatase 2C 17 180 2.0E-8 T 12-10-2018 UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 10 350 61.609 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 Pfam PF00814 Glycoprotease family 36 324 6.2E-97 T 12-10-2018 IPR000905 Gcp-like domain UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 ProSitePatterns PS01016 Glycoprotease family signature. 109 129 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 Gene3D G3DSA:3.30.420.40 142 311 1.2E-114 T 12-10-2018 UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 12 330 4.1E-124 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 Gene3D G3DSA:3.30.420.40 12 332 1.2E-114 T 12-10-2018 UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 89 109 6.4E-51 T 12-10-2018 IPR017861 Kae1/TsaD family UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 110 129 6.4E-51 T 12-10-2018 IPR017861 Kae1/TsaD family UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 144 156 6.4E-51 T 12-10-2018 IPR017861 Kae1/TsaD family UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 168 189 6.4E-51 T 12-10-2018 IPR017861 Kae1/TsaD family UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 13 26 6.4E-51 T 12-10-2018 IPR017861 Kae1/TsaD family UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 281 290 6.4E-51 T 12-10-2018 IPR017861 Kae1/TsaD family UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 SUPERFAMILY SSF53067 11 326 3.02E-36 T 12-10-2018 UA74_27940 af5e2502c0abbb46f6537360fa41d21d 355 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 13 324 8.0E-96 T 12-10-2018 IPR017861 Kae1/TsaD family UA74_15670 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Gene3D G3DSA:3.40.50.300 161 292 1.6E-19 T 12-10-2018 UA74_15670 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Pfam PF13538 UvrD-like helicase C-terminal domain 501 556 3.8E-7 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain UA74_15670 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Gene3D G3DSA:3.40.50.300 491 566 3.6E-6 T 12-10-2018 UA74_15670 0a25dfe3b2f3fb7665a84d4b90ab2217 589 SUPERFAMILY SSF52540 2 560 3.19E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15670 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Pfam PF00580 UvrD/REP helicase N-terminal domain 193 264 5.1E-15 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UA74_15670 0a25dfe3b2f3fb7665a84d4b90ab2217 589 Gene3D G3DSA:3.40.50.300 1 119 1.1E-8 T 12-10-2018 UA74_02750 2a27887074883943939aba29a7be3a8f 344 SUPERFAMILY SSF53448 49 333 8.55E-83 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_02750 2a27887074883943939aba29a7be3a8f 344 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 50 334 3.2E-138 T 12-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 UA74_02750 2a27887074883943939aba29a7be3a8f 344 Gene3D G3DSA:3.90.550.10 47 340 6.6E-75 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_02750 2a27887074883943939aba29a7be3a8f 344 Pfam PF00483 Nucleotidyl transferase 50 285 2.7E-60 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_04170 5878f59038b8c3de6622867bb4d84caf 433 Pfam PF02601 Exonuclease VII, large subunit 148 361 5.1E-57 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 UA74_04170 5878f59038b8c3de6622867bb4d84caf 433 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 24 424 23.128 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 UA74_04170 5878f59038b8c3de6622867bb4d84caf 433 Pfam PF13742 OB-fold nucleic acid binding domain 31 125 3.3E-15 T 12-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 UA74_04170 5878f59038b8c3de6622867bb4d84caf 433 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 32 423 2.1E-109 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 UA74_11565 0c731d427166bb20533430d412fbff11 143 SUPERFAMILY SSF141322 78 139 3.79E-7 T 12-10-2018 UA74_11565 0c731d427166bb20533430d412fbff11 143 Pfam PF01957 NfeD-like C-terminal, partner-binding 5 140 5.5E-22 T 12-10-2018 IPR002810 NfeD-like, C-terminal domain UA74_11565 0c731d427166bb20533430d412fbff11 143 Gene3D G3DSA:2.40.50.140 81 141 1.2E-19 T 12-10-2018 UA74_01120 df73b123bc3ad649527784f6d28a12be 141 SUPERFAMILY SSF82784 2 138 7.85E-41 T 12-10-2018 IPR036102 OsmC/Ohr superfamily UA74_01120 df73b123bc3ad649527784f6d28a12be 141 Pfam PF02566 OsmC-like protein 41 137 1.7E-20 T 12-10-2018 IPR003718 OsmC/Ohr family UA74_01120 df73b123bc3ad649527784f6d28a12be 141 Gene3D G3DSA:2.20.25.10 1 45 8.6E-15 T 12-10-2018 UA74_01120 df73b123bc3ad649527784f6d28a12be 141 Gene3D G3DSA:3.30.300.20 46 139 1.2E-34 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta UA74_01120 df73b123bc3ad649527784f6d28a12be 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 138 1.6E-49 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 SUPERFAMILY SSF158472 115 164 4.18E-6 T 12-10-2018 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 Pfam PF00512 His Kinase A (phospho-acceptor) domain 168 231 1.4E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 Gene3D G3DSA:3.30.565.10 234 381 6.6E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 380 3.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 361 3.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 337 3.0E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 Pfam PF00672 HAMP domain 114 162 1.2E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 SMART SM00304 113 166 8.4E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 275 381 4.4E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 SUPERFAMILY SSF47384 151 231 4.51E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 SUPERFAMILY SSF55874 221 384 7.73E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 SMART SM00388 167 232 1.3E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 Gene3D G3DSA:1.10.287.130 117 233 4.5E-25 T 12-10-2018 UA74_07785 a6d77b10da99b6e127cbd0eecd9c059f 400 SMART SM00387 275 383 1.3E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_06475 ab4042b7e8fe1be58f0c2a53d3920386 419 Gene3D G3DSA:3.40.47.10 1 263 9.7E-38 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_06475 ab4042b7e8fe1be58f0c2a53d3920386 419 SMART SM00825 Beta-ketoacyl synthase 6 419 6.0E-10 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_06475 ab4042b7e8fe1be58f0c2a53d3920386 419 SUPERFAMILY SSF53901 224 418 6.12E-58 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_06475 ab4042b7e8fe1be58f0c2a53d3920386 419 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 376 1.4E-30 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_06475 ab4042b7e8fe1be58f0c2a53d3920386 419 Gene3D G3DSA:3.40.47.10 264 408 1.6E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_06475 ab4042b7e8fe1be58f0c2a53d3920386 419 SUPERFAMILY SSF53901 4 261 5.52E-33 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_06475 ab4042b7e8fe1be58f0c2a53d3920386 419 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 253 1.5E-22 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_06350 85f1d573c8cc5c2c061f5839aaf577a6 105 SUPERFAMILY SSF140453 5 101 4.05E-11 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_06350 85f1d573c8cc5c2c061f5839aaf577a6 105 Gene3D G3DSA:1.10.287.1060 3 102 6.0E-18 T 12-10-2018 UA74_06350 85f1d573c8cc5c2c061f5839aaf577a6 105 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 3 99 2.4E-9 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 UA74_12960 aec66d4cb7afe09f97fe1ebbaca37c93 385 SUPERFAMILY SSF55920 155 382 9.94E-71 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like UA74_12960 aec66d4cb7afe09f97fe1ebbaca37c93 385 Gene3D G3DSA:3.40.350.10 5 153 1.1E-30 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UA74_12960 aec66d4cb7afe09f97fe1ebbaca37c93 385 Pfam PF01321 Creatinase/Prolidase N-terminal domain 17 156 9.8E-12 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 UA74_12960 aec66d4cb7afe09f97fe1ebbaca37c93 385 Pfam PF00557 Metallopeptidase family M24 165 367 2.7E-59 T 12-10-2018 IPR000994 Peptidase M24 UA74_12960 aec66d4cb7afe09f97fe1ebbaca37c93 385 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 313 325 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site UA74_12960 aec66d4cb7afe09f97fe1ebbaca37c93 385 SUPERFAMILY SSF53092 10 154 6.8E-17 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UA74_12960 aec66d4cb7afe09f97fe1ebbaca37c93 385 Gene3D G3DSA:3.90.230.10 154 385 2.4E-79 T 12-10-2018 UA74_06705 d5efdfed01b8577721eff30d4f6178ab 676 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 99 664 1.8E-84 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_06705 d5efdfed01b8577721eff30d4f6178ab 676 Gene3D G3DSA:3.20.20.80 127 571 1.3E-114 T 12-10-2018 UA74_06705 d5efdfed01b8577721eff30d4f6178ab 676 SUPERFAMILY SSF51445 123 672 5.56E-136 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_06705 d5efdfed01b8577721eff30d4f6178ab 676 Pfam PF02446 4-alpha-glucanotransferase 136 652 1.7E-110 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 UA74_10430 159db1039939ad76af50c128998d3b7c 229 SUPERFAMILY SSF51735 6 211 3.94E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_10430 159db1039939ad76af50c128998d3b7c 229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 199 0.0024 T 12-10-2018 UA74_10430 159db1039939ad76af50c128998d3b7c 229 Gene3D G3DSA:3.40.50.720 4 227 1.9E-47 T 12-10-2018 UA74_10430 159db1039939ad76af50c128998d3b7c 229 Pfam PF00106 short chain dehydrogenase 7 184 1.1E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10430 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 1.2E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10430 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 1.2E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10430 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 1.2E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10430 159db1039939ad76af50c128998d3b7c 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_10430 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 209 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10430 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10430 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10430 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10430 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_10430 159db1039939ad76af50c128998d3b7c 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.5E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_23700 0241a4a066ee5ec743e940a3c05b35f3 141 Pfam PF01641 SelR domain 17 136 2.0E-50 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 UA74_23700 0241a4a066ee5ec743e940a3c05b35f3 141 SUPERFAMILY SSF51316 12 140 1.1E-53 T 12-10-2018 IPR011057 Mss4-like superfamily UA74_23700 0241a4a066ee5ec743e940a3c05b35f3 141 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 13 139 4.8E-48 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 UA74_23700 0241a4a066ee5ec743e940a3c05b35f3 141 Gene3D G3DSA:2.170.150.20 3 141 1.8E-56 T 12-10-2018 UA74_28725 71b84f7885fa91e05af169fa0cd5c9df 205 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 174 180 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_28725 71b84f7885fa91e05af169fa0cd5c9df 205 Gene3D G3DSA:3.30.160.70 43 119 1.5E-17 T 12-10-2018 UA74_28725 71b84f7885fa91e05af169fa0cd5c9df 205 SUPERFAMILY SSF53155 43 120 4.12E-17 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_28725 71b84f7885fa91e05af169fa0cd5c9df 205 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 126 203 2.8E-29 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_28725 71b84f7885fa91e05af169fa0cd5c9df 205 Gene3D G3DSA:1.10.10.10 123 205 5.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28725 71b84f7885fa91e05af169fa0cd5c9df 205 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 47 204 36.228 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 UA74_28725 71b84f7885fa91e05af169fa0cd5c9df 205 SUPERFAMILY SSF46767 124 203 2.22E-26 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 UA74_28725 71b84f7885fa91e05af169fa0cd5c9df 205 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 126 204 2.7E-27 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_28725 71b84f7885fa91e05af169fa0cd5c9df 205 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 45 120 5.8E-7 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_07290 1f6b5fded0009bc879c7683d65da2830 73 PRINTS PR00944 Copper ion binding protein signature 8 20 8.7E-9 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 UA74_07290 1f6b5fded0009bc879c7683d65da2830 73 PRINTS PR00944 Copper ion binding protein signature 20 33 8.7E-9 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 UA74_07290 1f6b5fded0009bc879c7683d65da2830 73 PRINTS PR00944 Copper ion binding protein signature 58 71 8.7E-9 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 UA74_07290 1f6b5fded0009bc879c7683d65da2830 73 PRINTS PR00944 Copper ion binding protein signature 33 46 8.7E-9 T 12-10-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 UA74_07290 1f6b5fded0009bc879c7683d65da2830 73 Pfam PF00403 Heavy-metal-associated domain 10 70 3.4E-16 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UA74_07290 1f6b5fded0009bc879c7683d65da2830 73 SUPERFAMILY SSF55008 3 72 4.71E-19 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 UA74_07290 1f6b5fded0009bc879c7683d65da2830 73 Gene3D G3DSA:3.30.70.100 8 71 1.1E-20 T 12-10-2018 UA74_07290 1f6b5fded0009bc879c7683d65da2830 73 ProSitePatterns PS01047 Heavy-metal-associated domain. 13 42 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 UA74_13770 4614f5e20bb7f39af14a9ee90d405ebd 738 Gene3D G3DSA:3.40.50.300 433 562 1.3E-10 T 12-10-2018 UA74_13770 4614f5e20bb7f39af14a9ee90d405ebd 738 Pfam PF00270 DEAD/DEAH box helicase 222 396 3.9E-8 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_13770 4614f5e20bb7f39af14a9ee90d405ebd 738 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 236 550 5.6E-38 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core UA74_13770 4614f5e20bb7f39af14a9ee90d405ebd 738 SMART SM00487 207 422 0.0016 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_13770 4614f5e20bb7f39af14a9ee90d405ebd 738 SUPERFAMILY SSF52540 225 556 1.12E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13770 4614f5e20bb7f39af14a9ee90d405ebd 738 Gene3D G3DSA:1.10.3210.30 12 134 5.3E-6 T 12-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily UA74_13770 4614f5e20bb7f39af14a9ee90d405ebd 738 Gene3D G3DSA:3.40.50.300 207 412 5.0E-14 T 12-10-2018 UA74_13770 4614f5e20bb7f39af14a9ee90d405ebd 738 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 15 171 6.8E-21 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain UA74_13995 470a74049e94c12c287abc9e26867e00 188 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 180 1.3E-79 T 12-10-2018 IPR021441 Protein of unknown function DUF3090 UA74_13995 470a74049e94c12c287abc9e26867e00 188 Pfam PF11290 Protein of unknown function (DUF3090) 6 176 1.8E-69 T 12-10-2018 IPR021441 Protein of unknown function DUF3090 UA74_15835 98e90bafbded1a342ca0931cd71b7cb4 87 Pfam PF09827 CRISPR associated protein Cas2 1 65 3.6E-14 T 12-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 UA74_15835 98e90bafbded1a342ca0931cd71b7cb4 87 Gene3D G3DSA:3.30.70.240 1 65 4.5E-23 T 12-10-2018 UA74_15835 98e90bafbded1a342ca0931cd71b7cb4 87 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 87 13.094 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_15835 98e90bafbded1a342ca0931cd71b7cb4 87 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 65 5.3E-8 T 12-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 UA74_15835 98e90bafbded1a342ca0931cd71b7cb4 87 SUPERFAMILY SSF143430 1 80 5.49E-20 T 12-10-2018 UA74_25025 8f9ff30709bb0aa61e906156ea56ed30 190 SUPERFAMILY SSF52540 13 189 9.16E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25025 8f9ff30709bb0aa61e906156ea56ed30 190 Gene3D G3DSA:3.40.50.300 13 190 2.3E-48 T 12-10-2018 UA74_25025 8f9ff30709bb0aa61e906156ea56ed30 190 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 13 189 9.9E-52 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 UA74_25025 8f9ff30709bb0aa61e906156ea56ed30 190 PIRSF PIRSF006135 11 190 2.9E-48 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 UA74_11750 db8e473a578099ab6664c181738faba1 260 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 257 8.3E-36 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_11750 db8e473a578099ab6664c181738faba1 260 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 36 257 1.8E-89 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_11750 db8e473a578099ab6664c181738faba1 260 Gene3D G3DSA:1.10.10.10 111 163 2.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_11750 db8e473a578099ab6664c181738faba1 260 PRINTS PR00046 Major sigma-70 factor signature 242 253 1.1E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_11750 db8e473a578099ab6664c181738faba1 260 PRINTS PR00046 Major sigma-70 factor signature 227 242 1.1E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_11750 db8e473a578099ab6664c181738faba1 260 PRINTS PR00046 Major sigma-70 factor signature 210 222 1.1E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_11750 db8e473a578099ab6664c181738faba1 260 PRINTS PR00046 Major sigma-70 factor signature 65 78 1.1E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_11750 db8e473a578099ab6664c181738faba1 260 Pfam PF04545 Sigma-70, region 4 206 255 3.2E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UA74_11750 db8e473a578099ab6664c181738faba1 260 SUPERFAMILY SSF88659 114 187 2.31E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_11750 db8e473a578099ab6664c181738faba1 260 SUPERFAMILY SSF88659 179 258 3.74E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_11750 db8e473a578099ab6664c181738faba1 260 Pfam PF04542 Sigma-70 region 2 41 110 1.2E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_11750 db8e473a578099ab6664c181738faba1 260 Gene3D G3DSA:1.10.10.10 185 259 3.9E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_11750 db8e473a578099ab6664c181738faba1 260 SUPERFAMILY SSF88946 11 110 5.89E-29 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_11750 db8e473a578099ab6664c181738faba1 260 Gene3D G3DSA:1.20.120.1810 8 109 9.4E-20 T 12-10-2018 UA74_11750 db8e473a578099ab6664c181738faba1 260 Pfam PF04539 Sigma-70 region 3 124 194 1.3E-12 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UA74_15175 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00412 Epoxide hydrolase signature 27 45 6.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15175 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00412 Epoxide hydrolase signature 47 62 6.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15175 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00412 Epoxide hydrolase signature 214 230 6.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15175 c410682bf38a26e7d20b409cbf7862a5 275 Pfam PF00561 alpha/beta hydrolase fold 22 253 2.5E-27 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15175 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15175 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 1.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15175 c410682bf38a26e7d20b409cbf7862a5 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.4E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15175 c410682bf38a26e7d20b409cbf7862a5 275 Gene3D G3DSA:3.40.50.1820 2 274 1.4E-79 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15175 c410682bf38a26e7d20b409cbf7862a5 275 SUPERFAMILY SSF53474 2 274 1.17E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20340 f5402e0f88e196b27371eac2233ce6c8 444 Pfam PF13088 BNR repeat-like domain 101 398 5.8E-21 T 12-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_20340 f5402e0f88e196b27371eac2233ce6c8 444 SUPERFAMILY SSF50939 83 431 1.6E-63 T 12-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 UA74_20340 f5402e0f88e196b27371eac2233ce6c8 444 Gene3D G3DSA:2.120.10.10 57 437 1.9E-108 T 12-10-2018 UA74_04900 23abf04e8b46d0bd944107345785357b 985 Pfam PF03699 Uncharacterised protein family (UPF0182) 12 811 5.9E-279 T 12-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 UA74_04900 23abf04e8b46d0bd944107345785357b 985 Hamap MF_01600 UPF0182 protein . 3 888 18.301 T 12-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 UA74_05265 25a169e64adb12fe2be93e17ddbe3139 395 Pfam PF07730 Histidine kinase 192 256 4.4E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_05265 25a169e64adb12fe2be93e17ddbe3139 395 SUPERFAMILY SSF55874 282 390 2.15E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_05265 25a169e64adb12fe2be93e17ddbe3139 395 Gene3D G3DSA:3.30.565.10 266 391 3.8E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_04065 b30d971cdf9504e1f63aa33c9aa73fa7 125 Gene3D G3DSA:1.10.10.10 11 125 4.1E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04065 b30d971cdf9504e1f63aa33c9aa73fa7 125 Pfam PF01638 HxlR-like helix-turn-helix 33 115 2.9E-23 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_04065 b30d971cdf9504e1f63aa33c9aa73fa7 125 SUPERFAMILY SSF46785 24 115 6.51E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_09330 53a4bfcaff6c449aabaef0465b6b5e8a 351 SUPERFAMILY SSF53098 132 269 1.52E-9 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_09330 53a4bfcaff6c449aabaef0465b6b5e8a 351 Gene3D G3DSA:3.30.420.10 130 283 1.6E-11 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_16390 a291ebf52e89707d2964e1e08dc3d58c 328 Pfam PF13011 leucine-zipper of insertion element IS481 1 47 3.0E-14 T 12-10-2018 IPR024967 DNA-binding domain, IS481-type UA74_16390 a291ebf52e89707d2964e1e08dc3d58c 328 SUPERFAMILY SSF53098 142 201 2.02E-6 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_16390 a291ebf52e89707d2964e1e08dc3d58c 328 Pfam PF00665 Integrase core domain 103 201 3.8E-14 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 UA74_16390 a291ebf52e89707d2964e1e08dc3d58c 328 SUPERFAMILY SSF46689 1 76 2.06E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_22150 999accef9cfca7ebc45d5885318e436a 373 SUPERFAMILY SSF51735 7 153 1.1E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22150 999accef9cfca7ebc45d5885318e436a 373 Gene3D G3DSA:3.40.50.720 1 130 3.9E-30 T 12-10-2018 UA74_22150 999accef9cfca7ebc45d5885318e436a 373 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 123 1.4E-15 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_22150 999accef9cfca7ebc45d5885318e436a 373 SUPERFAMILY SSF55347 135 320 1.34E-25 T 12-10-2018 UA74_22150 999accef9cfca7ebc45d5885318e436a 373 Gene3D G3DSA:3.30.360.10 134 349 5.9E-30 T 12-10-2018 UA74_03695 eddf4bea12e34541a3f77a7f1b8df42f 581 Gene3D G3DSA:3.50.30.80 380 534 1.6E-47 T 12-10-2018 UA74_03695 eddf4bea12e34541a3f77a7f1b8df42f 581 SUPERFAMILY SSF52016 381 569 2.12E-53 T 12-10-2018 UA74_03695 eddf4bea12e34541a3f77a7f1b8df42f 581 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 127 137 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_03695 eddf4bea12e34541a3f77a7f1b8df42f 581 SUPERFAMILY SSF143975 16 379 8.76E-112 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_03695 eddf4bea12e34541a3f77a7f1b8df42f 581 Pfam PF00920 Dehydratase family 45 563 3.6E-167 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UA74_17160 8eb7ffde227dd1127cdcdf1554664cfe 298 SUPERFAMILY SSF52768 4 288 4.32E-43 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily UA74_17160 8eb7ffde227dd1127cdcdf1554664cfe 298 Gene3D G3DSA:3.40.800.10 2 296 3.8E-52 T 12-10-2018 UA74_17160 8eb7ffde227dd1127cdcdf1554664cfe 298 Pfam PF00491 Arginase family 71 289 6.9E-23 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 UA74_07120 4a572a73b0c67ae671f612504b1d8603 196 Pfam PF00293 NUDIX domain 43 152 1.4E-9 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_07120 4a572a73b0c67ae671f612504b1d8603 196 SUPERFAMILY SSF55811 2 173 7.72E-34 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_07120 4a572a73b0c67ae671f612504b1d8603 196 Gene3D G3DSA:3.90.79.10 1 184 9.2E-39 T 12-10-2018 UA74_25705 76b02d1b48e53448a7700d63fde4587e 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 15.995 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_25705 76b02d1b48e53448a7700d63fde4587e 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 1.1E-20 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_25705 76b02d1b48e53448a7700d63fde4587e 63 Gene3D G3DSA:2.30.170.40 19 63 1.3E-18 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_25705 76b02d1b48e53448a7700d63fde4587e 63 SUPERFAMILY SSF143800 2 62 9.22E-22 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_25705 76b02d1b48e53448a7700d63fde4587e 63 Pfam PF00830 Ribosomal L28 family 4 59 2.3E-21 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_14270 0e022ffcd2b5b1430ba2a409987cd934 86 Gene3D G3DSA:3.20.20.30 1 86 9.8E-20 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_14270 0e022ffcd2b5b1430ba2a409987cd934 86 SUPERFAMILY SSF51679 4 85 1.33E-17 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_14270 0e022ffcd2b5b1430ba2a409987cd934 86 Pfam PF00296 Luciferase-like monooxygenase 5 84 7.5E-17 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_09065 df95a84199c5751f92093d1060c29ea3 412 Gene3D G3DSA:1.20.1250.20 225 409 2.0E-16 T 12-10-2018 UA74_09065 df95a84199c5751f92093d1060c29ea3 412 SUPERFAMILY SSF103473 32 408 2.49E-39 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_09065 df95a84199c5751f92093d1060c29ea3 412 Gene3D G3DSA:1.20.1250.20 25 215 2.0E-12 T 12-10-2018 UA74_09065 df95a84199c5751f92093d1060c29ea3 412 Pfam PF07690 Major Facilitator Superfamily 37 372 1.1E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_17430 f84aed6a952b8174c3efb43aa9869fea 375 Gene3D G3DSA:3.40.710.10 38 363 9.0E-82 T 12-10-2018 UA74_17430 f84aed6a952b8174c3efb43aa9869fea 375 Pfam PF00144 Beta-lactamase 47 352 1.2E-44 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_17430 f84aed6a952b8174c3efb43aa9869fea 375 SUPERFAMILY SSF56601 38 353 6.16E-66 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_28315 c6beb6a4e687cf036f4a4f3fdf17c673 627 Pfam PF05977 Transmembrane secretion effector 39 429 2.7E-55 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_28315 c6beb6a4e687cf036f4a4f3fdf17c673 627 Gene3D G3DSA:1.20.1250.20 45 428 8.3E-47 T 12-10-2018 UA74_28315 c6beb6a4e687cf036f4a4f3fdf17c673 627 SUPERFAMILY SSF103473 47 433 8.63E-46 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_24580 b54eec6d150d4468c9500deffb890d69 257 SUPERFAMILY SSF53335 38 190 2.27E-20 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_24580 b54eec6d150d4468c9500deffb890d69 257 Gene3D G3DSA:3.40.50.150 16 191 1.1E-17 T 12-10-2018 UA74_24580 b54eec6d150d4468c9500deffb890d69 257 Pfam PF13489 Methyltransferase domain 38 161 1.0E-10 T 12-10-2018 UA74_23110 23c342f83f8d47e6e0ed479567d6a70b 105 Gene3D G3DSA:3.10.290.10 31 102 4.5E-21 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UA74_23110 23c342f83f8d47e6e0ed479567d6a70b 105 SUPERFAMILY SSF55174 29 99 3.4E-18 T 12-10-2018 UA74_23110 23c342f83f8d47e6e0ed479567d6a70b 105 Pfam PF13275 S4 domain 37 100 8.5E-24 T 12-10-2018 UA74_08700 822cf3e7993438cb3ba2f8b683d3df75 395 Gene3D G3DSA:3.40.980.20 220 389 2.0E-22 T 12-10-2018 UA74_08700 822cf3e7993438cb3ba2f8b683d3df75 395 SUPERFAMILY SSF142764 5 386 6.15E-85 T 12-10-2018 UA74_08700 822cf3e7993438cb3ba2f8b683d3df75 395 Gene3D G3DSA:3.40.50.10840 5 219 6.2E-57 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily UA74_08700 822cf3e7993438cb3ba2f8b683d3df75 395 Pfam PF07005 Putative sugar-binding N-terminal domain 5 215 8.2E-48 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain UA74_08700 822cf3e7993438cb3ba2f8b683d3df75 395 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 229 381 8.5E-23 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain UA74_13330 258d7832e964cb8c7104c858c57791f0 461 Pfam PF14315 Domain of unknown function (DUF4380) 40 332 6.5E-12 T 12-10-2018 IPR025488 Protein of unknown function DUF4380 UA74_05725 298b6a4fe28c7d26f434c2cf11571be3 354 SUPERFAMILY SSF101790 280 330 1.8E-6 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal UA74_05725 298b6a4fe28c7d26f434c2cf11571be3 354 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 255 330 7.4E-11 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_05725 298b6a4fe28c7d26f434c2cf11571be3 354 SUPERFAMILY SSF103025 12 265 2.2E-46 T 12-10-2018 UA74_05725 298b6a4fe28c7d26f434c2cf11571be3 354 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 247 6.6E-35 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain UA74_05725 298b6a4fe28c7d26f434c2cf11571be3 354 PIRSF PIRSF006487 1 347 1.3E-40 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UA74_05725 298b6a4fe28c7d26f434c2cf11571be3 354 Gene3D G3DSA:3.30.1360.120 2 344 2.4E-55 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_19265 745a8235dfb51cb1b3b38870cc787ced 308 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 216 297 1.2E-5 T 12-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 UA74_19265 745a8235dfb51cb1b3b38870cc787ced 308 SUPERFAMILY SSF69304 40 306 2.22E-22 T 12-10-2018 UA74_19265 745a8235dfb51cb1b3b38870cc787ced 308 Gene3D G3DSA:2.140.10.30 233 307 1.1E-6 T 12-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily UA74_19265 745a8235dfb51cb1b3b38870cc787ced 308 Gene3D G3DSA:2.120.10.30 36 232 3.5E-20 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_19265 745a8235dfb51cb1b3b38870cc787ced 308 Pfam PF07676 WD40-like Beta Propeller Repeat 114 129 0.0017 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_15070 8e980711a5d2273e8908727c7759fd7b 303 SMART SM00530 10 83 1.0E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_15070 8e980711a5d2273e8908727c7759fd7b 303 Gene3D G3DSA:3.30.450.180 110 271 1.3E-19 T 12-10-2018 UA74_15070 8e980711a5d2273e8908727c7759fd7b 303 SUPERFAMILY SSF47413 29 82 1.42E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_15070 8e980711a5d2273e8908727c7759fd7b 303 Gene3D G3DSA:1.10.260.40 4 85 9.4E-9 T 12-10-2018 UA74_15070 8e980711a5d2273e8908727c7759fd7b 303 Pfam PF13560 Helix-turn-helix domain 7 86 7.1E-18 T 12-10-2018 UA74_01930 4cf5bfbfaf39d41a3ef113b5d6c1c2cc 231 Pfam PF02581 Thiamine monophosphate synthase 22 211 2.8E-50 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_01930 4cf5bfbfaf39d41a3ef113b5d6c1c2cc 231 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 21 224 1.0E-59 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_01930 4cf5bfbfaf39d41a3ef113b5d6c1c2cc 231 SUPERFAMILY SSF51391 16 226 4.19E-59 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_01930 4cf5bfbfaf39d41a3ef113b5d6c1c2cc 231 Gene3D G3DSA:3.20.20.70 11 230 9.9E-70 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_01930 4cf5bfbfaf39d41a3ef113b5d6c1c2cc 231 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 19 229 25.158 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UA74_16835 6ec5b575075b0de01f66725678872603 302 Pfam PF00106 short chain dehydrogenase 16 206 3.6E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16835 6ec5b575075b0de01f66725678872603 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16835 6ec5b575075b0de01f66725678872603 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 2.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16835 6ec5b575075b0de01f66725678872603 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16835 6ec5b575075b0de01f66725678872603 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.1E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16835 6ec5b575075b0de01f66725678872603 302 Gene3D G3DSA:3.40.50.720 1 293 1.1E-90 T 12-10-2018 UA74_16835 6ec5b575075b0de01f66725678872603 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16835 6ec5b575075b0de01f66725678872603 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.2E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_16835 6ec5b575075b0de01f66725678872603 302 SUPERFAMILY SSF51735 13 241 7.74E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12655 a7bfe5701986ffadfbdae8241352cecf 229 Pfam PF06439 Domain of Unknown Function (DUF1080) 52 223 1.5E-42 T 12-10-2018 IPR010496 Domain of unknown function DUF1080 UA74_12655 a7bfe5701986ffadfbdae8241352cecf 229 Gene3D G3DSA:2.60.120.560 44 226 2.5E-43 T 12-10-2018 UA74_17295 3914f8b571098ecec698f4cf81aacdaa 449 Gene3D G3DSA:3.40.50.720 219 365 9.8E-214 T 12-10-2018 UA74_17295 3914f8b571098ecec698f4cf81aacdaa 449 Pfam PF00107 Zinc-binding dehydrogenase 236 379 3.5E-34 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_17295 3914f8b571098ecec698f4cf81aacdaa 449 SUPERFAMILY SSF50129 47 230 6.63E-30 T 12-10-2018 IPR011032 GroES-like superfamily UA74_17295 3914f8b571098ecec698f4cf81aacdaa 449 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 225 246 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UA74_17295 3914f8b571098ecec698f4cf81aacdaa 449 Gene3D G3DSA:3.90.180.10 11 433 9.8E-214 T 12-10-2018 UA74_17295 3914f8b571098ecec698f4cf81aacdaa 449 SMART SM00829 51 415 1.3E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_17295 3914f8b571098ecec698f4cf81aacdaa 449 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 112 190 6.8E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_17295 3914f8b571098ecec698f4cf81aacdaa 449 SUPERFAMILY SSF51735 195 386 3.97E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17295 3914f8b571098ecec698f4cf81aacdaa 449 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 33 427 3.3E-175 T 12-10-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 UA74_11385 dfc10f1d4c24f84ab53d3bbb7caec7c0 153 SMART SM00240 72 122 2.0E-16 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_11385 dfc10f1d4c24f84ab53d3bbb7caec7c0 153 Gene3D G3DSA:2.60.200.20 20 147 4.7E-42 T 12-10-2018 UA74_11385 dfc10f1d4c24f84ab53d3bbb7caec7c0 153 SUPERFAMILY SSF49879 37 143 2.3E-32 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 UA74_11385 dfc10f1d4c24f84ab53d3bbb7caec7c0 153 Pfam PF00498 FHA domain 74 136 1.9E-19 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_29780 60044294f8d232dfeefa97c3554af27a 193 Gene3D G3DSA:2.70.40.10 1 186 2.1E-58 T 12-10-2018 IPR036157 dUTPase-like superfamily UA74_29780 60044294f8d232dfeefa97c3554af27a 193 SUPERFAMILY SSF51283 2 183 1.7E-56 T 12-10-2018 IPR036157 dUTPase-like superfamily UA74_29780 60044294f8d232dfeefa97c3554af27a 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 4.9E-63 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 UA74_29780 60044294f8d232dfeefa97c3554af27a 193 Pfam PF00692 dUTPase 70 176 7.5E-10 T 12-10-2018 IPR029054 dUTPase-like UA74_29780 60044294f8d232dfeefa97c3554af27a 193 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 34.449 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 12-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 Pfam PF00334 Nucleoside diphosphate kinase 3 134 2.7E-52 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 SMART SM00562 2 136 1.4E-71 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 SUPERFAMILY SSF54919 3 135 2.23E-53 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 6.8E-42 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 6.8E-42 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 6.8E-42 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 6.8E-42 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 6.8E-42 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 Gene3D G3DSA:3.30.70.141 1 136 2.0E-56 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_08140 fc94a161b7bfc6dc5d474920a0c046b1 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 34.032 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 Gene3D G3DSA:3.40.50.2300 187 355 1.7E-46 T 12-10-2018 UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 1.4E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 1.4E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 SUPERFAMILY SSF53822 83 359 1.31E-34 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 Gene3D G3DSA:3.40.50.2300 83 350 1.7E-46 T 12-10-2018 UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 Gene3D G3DSA:1.10.10.10 4 56 3.4E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 SMART SM00420 7 59 1.2E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 Pfam PF08220 DeoR-like helix-turn-helix domain 7 60 3.3E-12 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 SUPERFAMILY SSF46785 6 59 3.52E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24165 588b39601bf83343fceaa2c263a1fc61 363 Pfam PF13377 Periplasmic binding protein-like domain 195 358 1.2E-31 T 12-10-2018 UA74_19620 8d0382a57a79fc046fd452b92124f415 603 Gene3D G3DSA:3.40.50.1820 345 590 1.0E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19620 8d0382a57a79fc046fd452b92124f415 603 SUPERFAMILY SSF53474 349 584 3.16E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19620 8d0382a57a79fc046fd452b92124f415 603 SUPERFAMILY SSF82171 41 331 1.37E-10 T 12-10-2018 UA74_19620 8d0382a57a79fc046fd452b92124f415 603 Pfam PF00326 Prolyl oligopeptidase family 383 587 1.6E-35 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_05550 affc85f634921896645176b99ff82abc 444 SUPERFAMILY SSF54826 6 135 6.01E-31 T 12-10-2018 UA74_05550 affc85f634921896645176b99ff82abc 444 SMART SM00922 184 284 4.3E-14 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_05550 affc85f634921896645176b99ff82abc 444 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 41 135 3.0E-5 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UA74_05550 affc85f634921896645176b99ff82abc 444 Pfam PF13378 Enolase C-terminal domain-like 190 403 2.8E-38 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_05550 affc85f634921896645176b99ff82abc 444 SUPERFAMILY SSF51604 137 413 4.98E-77 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_05550 affc85f634921896645176b99ff82abc 444 Gene3D G3DSA:3.30.390.10 9 412 4.5E-168 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_05550 affc85f634921896645176b99ff82abc 444 Gene3D G3DSA:3.20.20.120 137 398 4.5E-168 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 8 260 1.0E-82 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 178 196 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 Pfam PF00557 Metallopeptidase family M24 17 252 3.6E-43 T 12-10-2018 IPR000994 Peptidase M24 UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 Hamap MF_01974 Methionine aminopeptidase [map]. 8 261 37.711 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 172 184 1.1E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 203 215 1.1E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 1.1E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 96 112 1.1E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 SUPERFAMILY SSF55920 9 259 9.29E-75 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like UA74_03105 1f12e0c4bb74c41ddc3cec376f6d9447 263 Gene3D G3DSA:3.90.230.10 1 263 1.9E-90 T 12-10-2018 UA74_19825 1ad4eaaf525c9b0155305ffc8b767aab 311 PIRSF PIRSF000535 1 304 1.7E-72 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_19825 1ad4eaaf525c9b0155305ffc8b767aab 311 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_19825 1ad4eaaf525c9b0155305ffc8b767aab 311 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 288 2.6E-82 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_19825 1ad4eaaf525c9b0155305ffc8b767aab 311 Gene3D G3DSA:3.40.1190.20 1 309 2.0E-96 T 12-10-2018 IPR029056 Ribokinase-like UA74_19825 1ad4eaaf525c9b0155305ffc8b767aab 311 Pfam PF00294 pfkB family carbohydrate kinase 13 282 3.5E-38 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_19825 1ad4eaaf525c9b0155305ffc8b767aab 311 SUPERFAMILY SSF53613 2 282 2.34E-58 T 12-10-2018 IPR029056 Ribokinase-like UA74_19825 1ad4eaaf525c9b0155305ffc8b767aab 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 242 255 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_10240 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 Gene3D G3DSA:3.40.50.300 505 749 7.1E-22 T 12-10-2018 UA74_10240 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 Gene3D G3DSA:3.40.50.300 282 485 5.6E-24 T 12-10-2018 UA74_10240 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 SUPERFAMILY SSF52540 243 530 4.47E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10240 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 SMART SM00487 278 505 4.8E-9 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_10240 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 120 197 7.0E-9 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 UA74_10240 f2f2b745bff4fc93f981b8a74fe6f7e1 1048 Pfam PF04851 Type III restriction enzyme, res subunit 282 474 7.5E-13 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UA74_26695 07a8be1646f4cad0dfcd3ebb076e5a2b 519 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 215 383 1.4E-33 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_26695 07a8be1646f4cad0dfcd3ebb076e5a2b 519 Gene3D G3DSA:1.10.260.150 174 482 3.0E-61 T 12-10-2018 UA74_26695 07a8be1646f4cad0dfcd3ebb076e5a2b 519 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 215 384 1.3E-29 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 Pfam PF07731 Multicopper oxidase 408 514 2.0E-20 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 Pfam PF07732 Multicopper oxidase 162 204 3.7E-4 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 Pfam PF07732 Multicopper oxidase 75 137 5.5E-12 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 Gene3D G3DSA:2.60.40.420 39 116 7.7E-19 T 12-10-2018 IPR008972 Cupredoxin UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 Gene3D G3DSA:2.60.40.420 117 203 1.2E-21 T 12-10-2018 IPR008972 Cupredoxin UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 SUPERFAMILY SSF49503 211 342 2.54E-23 T 12-10-2018 IPR008972 Cupredoxin UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 Gene3D G3DSA:2.60.40.420 381 515 9.7E-42 T 12-10-2018 IPR008972 Cupredoxin UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 Gene3D G3DSA:2.60.40.420 204 380 5.7E-53 T 12-10-2018 IPR008972 Cupredoxin UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 SUPERFAMILY SSF49503 406 514 2.04E-26 T 12-10-2018 IPR008972 Cupredoxin UA74_11290 1483cfc6abc9e230967f98db0e2a4a67 515 SUPERFAMILY SSF49503 44 199 3.3E-22 T 12-10-2018 IPR008972 Cupredoxin UA74_07515 2135f594eeb8548f2299330b501cb950 158 SUPERFAMILY SSF54427 54 151 1.8E-11 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_07515 2135f594eeb8548f2299330b501cb950 158 Gene3D G3DSA:3.10.450.50 53 154 9.9E-18 T 12-10-2018 UA74_07515 2135f594eeb8548f2299330b501cb950 158 Pfam PF12680 SnoaL-like domain 61 144 2.4E-7 T 12-10-2018 IPR037401 SnoaL-like domain UA74_11805 28649f5739c64aec3e79801e116a4aba 186 Pfam PF01047 MarR family 95 138 1.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_11805 28649f5739c64aec3e79801e116a4aba 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 130 4.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_11805 28649f5739c64aec3e79801e116a4aba 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 134 150 4.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_11805 28649f5739c64aec3e79801e116a4aba 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 4.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_11805 28649f5739c64aec3e79801e116a4aba 186 SMART SM00347 76 173 2.2E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_11805 28649f5739c64aec3e79801e116a4aba 186 SUPERFAMILY SSF46785 56 184 1.58E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_11805 28649f5739c64aec3e79801e116a4aba 186 Gene3D G3DSA:1.10.10.10 24 186 1.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18285 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 182 253 3.2E-7 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UA74_18285 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 Gene3D G3DSA:3.90.180.10 44 388 9.1E-132 T 12-10-2018 UA74_18285 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 44 153 1.1E-25 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_18285 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 Gene3D G3DSA:3.40.50.720 187 351 9.1E-132 T 12-10-2018 UA74_18285 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 SUPERFAMILY SSF50129 4 196 8.78E-57 T 12-10-2018 IPR011032 GroES-like superfamily UA74_18285 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 2 403 2.7E-229 T 12-10-2018 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 UA74_18285 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 SUPERFAMILY SSF51735 172 363 1.08E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18285 15109ec3c4fb8c9a8a7ed43ac3daed0b 407 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 76 90 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_15140 18372fea1e1a662ab1e6dd00c1ff42af 123 Pfam PF00719 Inorganic pyrophosphatase 34 105 1.9E-6 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 UA74_15140 18372fea1e1a662ab1e6dd00c1ff42af 123 Gene3D G3DSA:3.90.80.10 5 119 8.6E-10 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 UA74_15140 18372fea1e1a662ab1e6dd00c1ff42af 123 SUPERFAMILY SSF50324 15 104 2.62E-13 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 UA74_29620 07d43d24e5a5781f59620699527207b2 203 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 203 23.632 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_29620 07d43d24e5a5781f59620699527207b2 203 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 34 197 4.6E-33 T 12-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_29620 07d43d24e5a5781f59620699527207b2 203 SUPERFAMILY SSF53271 25 199 9.57E-34 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_29620 07d43d24e5a5781f59620699527207b2 203 Gene3D G3DSA:3.40.50.2020 19 203 3.1E-48 T 12-10-2018 UA74_29620 07d43d24e5a5781f59620699527207b2 203 Pfam PF00156 Phosphoribosyl transferase domain 86 182 1.3E-12 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_05800 deadf68faa0918516aa9d842f349b1ba 408 SUPERFAMILY SSF53335 65 250 1.82E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_05800 deadf68faa0918516aa9d842f349b1ba 408 Pfam PF08421 Putative zinc binding domain 7 66 8.2E-20 T 12-10-2018 IPR013630 Methyltransferase putative zinc binding domain UA74_05800 deadf68faa0918516aa9d842f349b1ba 408 Gene3D G3DSA:2.20.25.520 1 56 1.2E-23 T 12-10-2018 IPR038576 Methyltransferase putative zinc binding domain superfamily UA74_05800 deadf68faa0918516aa9d842f349b1ba 408 Gene3D G3DSA:3.40.50.150 57 258 9.5E-49 T 12-10-2018 UA74_05800 deadf68faa0918516aa9d842f349b1ba 408 Gene3D G3DSA:3.40.50.720 310 408 4.0E-37 T 12-10-2018 UA74_05800 deadf68faa0918516aa9d842f349b1ba 408 Pfam PF13489 Methyltransferase domain 103 241 6.7E-19 T 12-10-2018 UA74_05800 deadf68faa0918516aa9d842f349b1ba 408 Pfam PF08484 C-methyltransferase C-terminal domain 247 403 3.7E-55 T 12-10-2018 IPR013691 C-methyltransferase UA74_25520 202e3bdfdfd1458c1afd9cba16f134ae 290 Pfam PF13560 Helix-turn-helix domain 15 75 1.1E-11 T 12-10-2018 UA74_25520 202e3bdfdfd1458c1afd9cba16f134ae 290 SUPERFAMILY SSF47413 13 70 7.74E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_25520 202e3bdfdfd1458c1afd9cba16f134ae 290 Gene3D G3DSA:1.10.260.40 6 78 7.8E-6 T 12-10-2018 UA74_05430 e21efe2f84b745265b554894d60c1a65 376 Pfam PF07730 Histidine kinase 188 251 9.1E-10 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_05430 e21efe2f84b745265b554894d60c1a65 376 Gene3D G3DSA:3.30.565.10 252 367 3.8E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 87 312 5.9E-36 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 SUPERFAMILY SSF88946 26 161 7.46E-52 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 284 310 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 SUPERFAMILY SSF88659 164 237 4.36E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 263 275 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 299 310 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 139 147 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 284 299 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 PRINTS PR00046 Major sigma-70 factor signature 115 128 5.0E-28 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 SUPERFAMILY SSF88659 221 319 4.3E-26 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 Pfam PF00140 Sigma-70 factor, region 1.2 26 59 1.9E-13 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 Pfam PF04545 Sigma-70, region 4 259 312 1.1E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 Pfam PF04542 Sigma-70 region 2 91 160 5.2E-22 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 Pfam PF04539 Sigma-70 region 3 170 246 7.1E-23 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 Gene3D G3DSA:1.20.120.1810 25 160 1.3E-51 T 12-10-2018 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 115 128 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 Gene3D G3DSA:1.10.10.10 247 324 6.5E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08350 aa71753a7e51dfcafa50a29c424ae659 324 Gene3D G3DSA:1.10.10.10 164 239 3.7E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22095 8f62777110e98c1bab7d1a6436aef0c0 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22095 8f62777110e98c1bab7d1a6436aef0c0 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.1E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22095 8f62777110e98c1bab7d1a6436aef0c0 188 SUPERFAMILY SSF46689 5 84 3.04E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_22095 8f62777110e98c1bab7d1a6436aef0c0 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 4.8E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22095 8f62777110e98c1bab7d1a6436aef0c0 188 Gene3D G3DSA:1.10.357.10 5 188 7.9E-51 T 12-10-2018 UA74_22095 8f62777110e98c1bab7d1a6436aef0c0 188 SUPERFAMILY SSF48498 102 182 1.46E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_04385 b309516337a651594cfb576541322245 374 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 302 6.2E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_04385 b309516337a651594cfb576541322245 374 SUPERFAMILY SSF52540 37 311 3.82E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04385 b309516337a651594cfb576541322245 374 Gene3D G3DSA:3.40.50.300 7 337 3.8E-95 T 12-10-2018 UA74_04385 b309516337a651594cfb576541322245 374 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_04385 b309516337a651594cfb576541322245 374 SMART SM00382 38 236 7.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_04385 b309516337a651594cfb576541322245 374 Pfam PF00005 ABC transporter 30 186 3.3E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_04385 b309516337a651594cfb576541322245 374 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 321 7.2E-25 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_17615 de843cc3a14285f28464fc4a3756e34e 340 SMART SM00829 10 338 3.1E-9 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UA74_17615 de843cc3a14285f28464fc4a3756e34e 340 SUPERFAMILY SSF51735 144 308 1.65E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17615 de843cc3a14285f28464fc4a3756e34e 340 Pfam PF00107 Zinc-binding dehydrogenase 181 301 5.4E-15 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UA74_17615 de843cc3a14285f28464fc4a3756e34e 340 SUPERFAMILY SSF50129 1 163 4.26E-44 T 12-10-2018 IPR011032 GroES-like superfamily UA74_17615 de843cc3a14285f28464fc4a3756e34e 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UA74_17615 de843cc3a14285f28464fc4a3756e34e 340 Gene3D G3DSA:3.40.50.720 154 289 3.0E-86 T 12-10-2018 UA74_17615 de843cc3a14285f28464fc4a3756e34e 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 6.5E-22 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_17615 de843cc3a14285f28464fc4a3756e34e 340 Gene3D G3DSA:3.90.180.10 13 335 3.0E-86 T 12-10-2018 UA74_21355 9c6e09be7e660232be04c38d759d7470 262 SUPERFAMILY SSF52540 3 229 5.13E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21355 9c6e09be7e660232be04c38d759d7470 262 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_21355 9c6e09be7e660232be04c38d759d7470 262 Gene3D G3DSA:3.40.50.300 3 254 5.1E-66 T 12-10-2018 UA74_21355 9c6e09be7e660232be04c38d759d7470 262 Pfam PF00005 ABC transporter 25 166 8.8E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_21355 9c6e09be7e660232be04c38d759d7470 262 SMART SM00382 28 216 2.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_05795 eb2a3204a61145918407a396f9dfc9a9 355 SUPERFAMILY SSF51735 26 344 1.46E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_05795 eb2a3204a61145918407a396f9dfc9a9 355 Gene3D G3DSA:3.40.50.720 25 344 4.3E-50 T 12-10-2018 UA74_05795 eb2a3204a61145918407a396f9dfc9a9 355 Pfam PF01370 NAD dependent epimerase/dehydratase family 28 265 9.6E-36 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 3.6E-41 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 3.6E-41 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 3.6E-41 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 3.6E-41 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 3.6E-41 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 3.6E-41 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82714 183 261 2.09E-11 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82693 135 321 1.48E-12 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82693 42 129 2.75E-21 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.2090.10 707 794 1.3E-279 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.70.1440 658 851 1.3E-279 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.2090.10 177 267 1.3E-279 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.70.1320 132 324 1.3E-279 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:1.20.1640.10 506 1009 1.3E-279 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82693 559 649 7.32E-7 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.70.1430 41 802 1.3E-279 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Pfam PF00873 AcrB/AcrD/AcrF family 5 1011 4.4E-224 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82714 708 791 6.93E-9 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:1.20.1640.10 12 505 1.3E-279 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82866 791 1015 5.89E-49 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 SUPERFAMILY SSF82866 290 489 7.46E-46 T 12-10-2018 UA74_21005 8f1c7eb3e2a1f227a97c405a6e7e1833 1039 Gene3D G3DSA:3.30.70.1430 559 657 1.3E-279 T 12-10-2018 UA74_03920 2873746389507f1464f059b4dbba7e4b 66 Pfam PF04149 Domain of unknown function (DUF397) 10 59 1.8E-14 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_23005 f9fad477204445af15261b2d295b9544 218 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 14 159 3.4E-27 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_23005 f9fad477204445af15261b2d295b9544 218 Hamap MF_00165 Thymidylate kinase [tmk]. 15 210 15.484 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UA74_23005 f9fad477204445af15261b2d295b9544 218 Gene3D G3DSA:3.40.50.300 11 213 5.5E-37 T 12-10-2018 UA74_23005 f9fad477204445af15261b2d295b9544 218 Pfam PF02223 Thymidylate kinase 19 167 1.7E-26 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 UA74_23005 f9fad477204445af15261b2d295b9544 218 SUPERFAMILY SSF52540 14 173 8.55E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20285 5c5d08cd05381661edce69d4fe8e3018 137 Gene3D G3DSA:3.30.450.30 6 132 5.0E-39 T 12-10-2018 UA74_20285 5c5d08cd05381661edce69d4fe8e3018 137 Pfam PF03259 Roadblock/LC7 domain 12 100 9.5E-21 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain UA74_20285 5c5d08cd05381661edce69d4fe8e3018 137 SUPERFAMILY SSF103196 2 129 1.33E-26 T 12-10-2018 UA74_20285 5c5d08cd05381661edce69d4fe8e3018 137 SMART SM00960 10 101 3.1E-20 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain UA74_24295 0f890b0eec672fae4361df998eedeb0c 349 SUPERFAMILY SSF51735 9 154 1.62E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_24295 0f890b0eec672fae4361df998eedeb0c 349 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 12 130 2.1E-14 T 12-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 UA74_24295 0f890b0eec672fae4361df998eedeb0c 349 Gene3D G3DSA:3.40.50.720 9 168 3.6E-28 T 12-10-2018 UA74_27795 0a507d775c5dec42a41bbef4b3f53094 300 Gene3D G3DSA:3.40.190.10 167 269 9.9E-43 T 12-10-2018 UA74_27795 0a507d775c5dec42a41bbef4b3f53094 300 SUPERFAMILY SSF53850 90 298 1.38E-34 T 12-10-2018 UA74_27795 0a507d775c5dec42a41bbef4b3f53094 300 Pfam PF03466 LysR substrate binding domain 88 294 1.8E-39 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_27795 0a507d775c5dec42a41bbef4b3f53094 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.3E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_27795 0a507d775c5dec42a41bbef4b3f53094 300 Gene3D G3DSA:1.10.10.10 1 93 5.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27795 0a507d775c5dec42a41bbef4b3f53094 300 Gene3D G3DSA:3.40.190.10 94 277 9.9E-43 T 12-10-2018 UA74_27795 0a507d775c5dec42a41bbef4b3f53094 300 SUPERFAMILY SSF46785 1 112 1.59E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_26240 fa36ec9ca631a31ac922a3f87f86a9ea 538 Pfam PF13556 PucR C-terminal helix-turn-helix domain 466 521 3.0E-17 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UA74_26240 fa36ec9ca631a31ac922a3f87f86a9ea 538 Gene3D G3DSA:1.10.10.2840 395 527 1.6E-18 T 12-10-2018 UA74_22560 9e05a9c2a9f61bcf776d3719def439e0 242 SUPERFAMILY SSF144010 14 232 1.31E-50 T 12-10-2018 UA74_22560 9e05a9c2a9f61bcf776d3719def439e0 242 Gene3D G3DSA:3.90.1660.10 61 234 3.9E-52 T 12-10-2018 UA74_22560 9e05a9c2a9f61bcf776d3719def439e0 242 Gene3D G3DSA:3.30.1330.100 13 233 3.9E-52 T 12-10-2018 UA74_22560 9e05a9c2a9f61bcf776d3719def439e0 242 Pfam PF01996 F420-0:Gamma-glutamyl ligase 18 224 1.1E-40 T 12-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 UA74_11245 77c0988f57434538cfacbc638e12947d 397 Gene3D G3DSA:3.90.1150.10 17 385 1.2E-104 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_11245 77c0988f57434538cfacbc638e12947d 397 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 205 225 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site UA74_11245 77c0988f57434538cfacbc638e12947d 397 Pfam PF00266 Aminotransferase class-V 21 384 6.8E-60 T 12-10-2018 IPR000192 Aminotransferase class V domain UA74_11245 77c0988f57434538cfacbc638e12947d 397 SUPERFAMILY SSF53383 6 390 6.95E-80 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_11245 77c0988f57434538cfacbc638e12947d 397 Gene3D G3DSA:3.40.640.10 31 288 1.2E-104 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_07770 81e212d8ee747844bd84e3c46ad9cced 1180 Gene3D G3DSA:2.20.140.10 2 71 1.0E-17 T 12-10-2018 IPR036930 WGR domain superfamily UA74_07770 81e212d8ee747844bd84e3c46ad9cced 1180 Pfam PF13569 Domain of unknown function (DUF4132) 919 1097 3.5E-50 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 UA74_07770 81e212d8ee747844bd84e3c46ad9cced 1180 Pfam PF05406 WGR domain 9 65 1.7E-10 T 12-10-2018 IPR008893 WGR domain UA74_00250 b89a92c2eed4608f777f2afff42edc10 215 Gene3D G3DSA:1.10.3720.10 16 207 3.3E-24 T 12-10-2018 IPR035906 MetI-like superfamily UA74_00250 b89a92c2eed4608f777f2afff42edc10 215 SUPERFAMILY SSF161098 14 199 6.15E-29 T 12-10-2018 IPR035906 MetI-like superfamily UA74_00250 b89a92c2eed4608f777f2afff42edc10 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 205 9.0E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 256 270 2.4E-6 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 393 407 2.4E-6 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 346 363 2.4E-6 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 325 345 2.4E-6 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 Gene3D G3DSA:2.60.40.10 484 560 7.4E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 Gene3D G3DSA:2.40.10.10 239 312 6.3E-41 T 12-10-2018 UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 Gene3D G3DSA:3.30.300.50 57 140 1.7E-7 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 378 389 - T 12-10-2018 IPR033116 Serine proteases, trypsin family, serine active site UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 Pfam PF00089 Trypsin 258 404 1.5E-5 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 690 722 0.0013 T 12-10-2018 UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 SUPERFAMILY SSF50494 240 402 8.71E-22 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_01655 019c5647a7afb6268cfbe7aa35d44040 733 Gene3D G3DSA:2.40.10.10 313 406 6.3E-41 T 12-10-2018 UA74_21700 67267cbe8b6b87a0f05871826f66709a 169 Gene3D G3DSA:3.10.20.80 1 50 2.2E-21 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_21700 67267cbe8b6b87a0f05871826f66709a 169 Gene3D G3DSA:3.30.110.10 51 146 4.9E-33 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 UA74_21700 67267cbe8b6b87a0f05871826f66709a 169 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 2 145 9.9E-54 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_21700 67267cbe8b6b87a0f05871826f66709a 169 SUPERFAMILY SSF55200 60 144 1.06E-30 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 UA74_21700 67267cbe8b6b87a0f05871826f66709a 169 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 50 5.1E-21 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_21700 67267cbe8b6b87a0f05871826f66709a 169 SUPERFAMILY SSF54364 1 53 1.01E-19 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_21700 67267cbe8b6b87a0f05871826f66709a 169 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 59 142 1.9E-33 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 UA74_21700 67267cbe8b6b87a0f05871826f66709a 169 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 145 23.483 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UA74_21700 67267cbe8b6b87a0f05871826f66709a 169 ProSitePatterns PS00938 Initiation factor 3 signature. 33 46 - T 12-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 UA74_10580 be6528c4e6211ad1f092723af5dda3e7 268 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_10580 be6528c4e6211ad1f092723af5dda3e7 268 SUPERFAMILY SSF52540 2 231 3.99E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10580 be6528c4e6211ad1f092723af5dda3e7 268 Pfam PF00005 ABC transporter 18 165 1.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_10580 be6528c4e6211ad1f092723af5dda3e7 268 SMART SM00382 25 249 5.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_10580 be6528c4e6211ad1f092723af5dda3e7 268 Gene3D G3DSA:3.40.50.300 1 248 1.4E-63 T 12-10-2018 UA74_25760 6d07d7988428affa894e1f7033edc284 131 Gene3D G3DSA:1.10.10.10 11 130 1.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_25760 6d07d7988428affa894e1f7033edc284 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 3.1E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_25760 6d07d7988428affa894e1f7033edc284 131 SMART SM00345 18 77 7.8E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_25760 6d07d7988428affa894e1f7033edc284 131 SUPERFAMILY SSF46785 7 86 8.67E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_03195 a1e85b94834e53ce6e036e80aaf36034 146 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 142 3.7E-32 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_03195 a1e85b94834e53ce6e036e80aaf36034 146 Pfam PF04075 F420H(2)-dependent quinone reductase 15 143 4.2E-50 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_03195 a1e85b94834e53ce6e036e80aaf36034 146 Gene3D G3DSA:2.30.110.10 1 144 5.5E-55 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_13535 72fc58e0c92ea00530f6093689587c3b 454 Pfam PF13556 PucR C-terminal helix-turn-helix domain 391 449 6.4E-18 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UA74_13535 72fc58e0c92ea00530f6093689587c3b 454 Gene3D G3DSA:1.10.10.2840 325 453 1.1E-23 T 12-10-2018 UA74_27095 caaf84692dd6635d2dcfd5413b5e1984 355 Gene3D G3DSA:3.40.50.2300 160 348 3.2E-70 T 12-10-2018 UA74_27095 caaf84692dd6635d2dcfd5413b5e1984 355 Pfam PF13407 Periplasmic binding protein domain 58 315 1.6E-39 T 12-10-2018 IPR025997 Periplasmic binding protein UA74_27095 caaf84692dd6635d2dcfd5413b5e1984 355 Gene3D G3DSA:3.40.50.2300 58 336 3.2E-70 T 12-10-2018 UA74_27095 caaf84692dd6635d2dcfd5413b5e1984 355 SUPERFAMILY SSF53822 55 348 2.36E-53 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_08760 ad381aa17ed7de46f20256ca9aec4531 133 Pfam PF12802 MarR family 36 77 8.7E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_08760 ad381aa17ed7de46f20256ca9aec4531 133 SUPERFAMILY SSF46785 19 127 5.96E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_08760 ad381aa17ed7de46f20256ca9aec4531 133 SMART SM00347 9 113 0.0033 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_08760 ad381aa17ed7de46f20256ca9aec4531 133 Gene3D G3DSA:1.10.10.10 3 127 3.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23580 3255d9547f447c1126c9b1cbbb988aba 385 Gene3D G3DSA:3.20.20.500 1 379 4.0E-178 T 12-10-2018 UA74_23580 3255d9547f447c1126c9b1cbbb988aba 385 SUPERFAMILY SSF51569 56 331 1.67E-14 T 12-10-2018 UA74_23580 3255d9547f447c1126c9b1cbbb988aba 385 Pfam PF06187 Protein of unknown function (DUF993) 3 383 3.9E-183 T 12-10-2018 IPR009334 Protein of unknown function DUF993 UA74_15260 35949fd19019d233ff20930b173ba734 228 SUPERFAMILY SSF52172 12 150 1.02E-27 T 12-10-2018 IPR011006 CheY-like superfamily UA74_15260 35949fd19019d233ff20930b173ba734 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 178 205 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_15260 35949fd19019d233ff20930b173ba734 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 218 2.7E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_15260 35949fd19019d233ff20930b173ba734 228 SMART SM00448 13 126 8.5E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_15260 35949fd19019d233ff20930b173ba734 228 SUPERFAMILY SSF46894 151 224 5.44E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_15260 35949fd19019d233ff20930b173ba734 228 Pfam PF00072 Response regulator receiver domain 15 126 4.0E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_15260 35949fd19019d233ff20930b173ba734 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 5.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_15260 35949fd19019d233ff20930b173ba734 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 5.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_15260 35949fd19019d233ff20930b173ba734 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 5.5E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_15260 35949fd19019d233ff20930b173ba734 228 Gene3D G3DSA:3.40.50.12740 13 224 2.8E-60 T 12-10-2018 UA74_15260 35949fd19019d233ff20930b173ba734 228 SMART SM00421 161 218 4.8E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_14920 0f751e2f1dd1eda63d7fdc6ef552c11f 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.4E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_14920 0f751e2f1dd1eda63d7fdc6ef552c11f 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.4E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_14920 0f751e2f1dd1eda63d7fdc6ef552c11f 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 7.4E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_14920 0f751e2f1dd1eda63d7fdc6ef552c11f 144 Gene3D G3DSA:1.10.1660.10 1 127 1.4E-27 T 12-10-2018 UA74_14920 0f751e2f1dd1eda63d7fdc6ef552c11f 144 SUPERFAMILY SSF46955 1 117 1.14E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_14920 0f751e2f1dd1eda63d7fdc6ef552c11f 144 Pfam PF13411 MerR HTH family regulatory protein 1 66 7.6E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_14920 0f751e2f1dd1eda63d7fdc6ef552c11f 144 SMART SM00422 1 69 6.7E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_22240 8bf4ee45a1d6d48ec3c259cf78a80208 339 SUPERFAMILY SSF53807 39 319 5.1E-35 T 12-10-2018 UA74_22240 8bf4ee45a1d6d48ec3c259cf78a80208 339 Gene3D G3DSA:3.40.50.1980 28 155 7.0E-24 T 12-10-2018 UA74_22240 8bf4ee45a1d6d48ec3c259cf78a80208 339 Pfam PF01497 Periplasmic binding protein 100 314 2.3E-19 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_22240 8bf4ee45a1d6d48ec3c259cf78a80208 339 Gene3D G3DSA:3.40.50.1980 165 335 1.8E-36 T 12-10-2018 UA74_10655 7894ce38a49cf8423c58edc6325b0add 308 Gene3D G3DSA:3.40.630.30 142 301 4.0E-17 T 12-10-2018 UA74_10655 7894ce38a49cf8423c58edc6325b0add 308 Pfam PF00583 Acetyltransferase (GNAT) family 198 292 2.7E-6 T 12-10-2018 IPR000182 GNAT domain UA74_10655 7894ce38a49cf8423c58edc6325b0add 308 SUPERFAMILY SSF55729 147 298 4.48E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_00540 bc663a42e10caccb23d905060ae5ec0e 401 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 114 392 1.4E-53 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 UA74_00540 bc663a42e10caccb23d905060ae5ec0e 401 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 2 398 2.1E-115 T 12-10-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 UA74_00540 bc663a42e10caccb23d905060ae5ec0e 401 SUPERFAMILY SSF63433 2 108 1.7E-15 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 UA74_00540 bc663a42e10caccb23d905060ae5ec0e 401 SUPERFAMILY SSF56529 111 398 2.09E-88 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 UA74_00540 bc663a42e10caccb23d905060ae5ec0e 401 Pfam PF09298 Fumarylacetoacetase N-terminal 18 108 3.4E-8 T 12-10-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 UA74_00540 bc663a42e10caccb23d905060ae5ec0e 401 Gene3D G3DSA:2.30.30.230 1 102 2.7E-11 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 UA74_00540 bc663a42e10caccb23d905060ae5ec0e 401 Gene3D G3DSA:3.90.850.10 106 401 9.9E-101 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 UA74_10630 49843e9b94d5c20099aa7c09480d608b 154 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 30 142 7.8E-30 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 UA74_10630 49843e9b94d5c20099aa7c09480d608b 154 SUPERFAMILY SSF54637 29 147 3.13E-28 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_10630 49843e9b94d5c20099aa7c09480d608b 154 Gene3D G3DSA:3.10.129.10 3 147 3.4E-47 T 12-10-2018 UA74_10630 49843e9b94d5c20099aa7c09480d608b 154 Pfam PF03061 Thioesterase superfamily 58 134 5.0E-15 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 UA74_28070 510c10a422b75044507cdf67df84740a 467 Gene3D G3DSA:3.10.20.90 4 85 1.4E-13 T 12-10-2018 UA74_28070 510c10a422b75044507cdf67df84740a 467 PIRSF PIRSF017804 1 462 2.2E-121 T 12-10-2018 IPR006707 Type VII secretion system membrane protein EccD UA74_28070 510c10a422b75044507cdf67df84740a 467 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 459 4.8E-85 T 12-10-2018 IPR006707 Type VII secretion system membrane protein EccD UA74_28070 510c10a422b75044507cdf67df84740a 467 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 84 4.2E-21 T 12-10-2018 IPR024962 YukD-like UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 Pfam PF00106 short chain dehydrogenase 3 187 3.2E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 SUPERFAMILY SSF51735 2 243 9.53E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 188 0.0085 T 12-10-2018 UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 Gene3D G3DSA:3.40.50.720 2 274 3.2E-71 T 12-10-2018 UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.9E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.9E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.9E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.9E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 3.9E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.9E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05515 cc58f3c5d2448a36df5e2c65785eb07c 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.5E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18730 56d39c80cc1c30e6afef48b033b0923e 297 Gene3D G3DSA:1.10.3720.10 27 287 5.4E-67 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18730 56d39c80cc1c30e6afef48b033b0923e 297 SUPERFAMILY SSF161098 30 297 2.88E-70 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18730 56d39c80cc1c30e6afef48b033b0923e 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 286 9.6E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_13305 c2bf835538fc1a6854adc8195d89142a 188 SUPERFAMILY SSF46689 4 60 1.09E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_13305 c2bf835538fc1a6854adc8195d89142a 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 60 3.2E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13305 c2bf835538fc1a6854adc8195d89142a 188 Gene3D G3DSA:1.10.10.60 4 56 1.4E-19 T 12-10-2018 UA74_13305 c2bf835538fc1a6854adc8195d89142a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13305 c2bf835538fc1a6854adc8195d89142a 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.7E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13305 c2bf835538fc1a6854adc8195d89142a 188 Gene3D G3DSA:1.10.357.10 57 185 1.9E-23 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 96 5.9E-16 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF00384 Molybdopterin oxidoreductase 320 463 2.3E-10 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF00384 Molybdopterin oxidoreductase 548 684 2.0E-7 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 168 178 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:2.20.25.90 264 316 9.9E-10 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 SUPERFAMILY SSF53706 254 719 6.18E-69 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:3.40.228.10 397 460 2.0E-13 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF01568 Molydopterin dinucleotide binding domain 755 830 8.2E-8 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 SUPERFAMILY SSF54292 18 93 2.03E-17 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 47 64 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 SMART SM00926 263 317 1.4E-5 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:2.40.40.20 751 839 3.8E-5 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 120 132 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 SUPERFAMILY SSF50692 749 829 3.25E-9 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 144 5.4E-16 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 SMART SM00929 105 145 3.1E-19 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 SUPERFAMILY SSF54862 98 259 5.02E-28 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:3.10.20.740 18 145 6.8E-32 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:3.30.70.20 151 213 2.2E-5 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:3.40.50.740 516 742 1.2E-27 T 12-10-2018 UA74_02590 d9242f1735984e91790b0b72a4f4688c 856 Gene3D G3DSA:3.40.50.740 327 396 2.0E-13 T 12-10-2018 UA74_27740 a443986578712323b3fa4fd2e0ecf931 233 SUPERFAMILY SSF46785 34 145 1.28E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_27740 a443986578712323b3fa4fd2e0ecf931 233 Gene3D G3DSA:1.10.10.10 33 152 5.0E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27740 a443986578712323b3fa4fd2e0ecf931 233 SMART SM00418 34 110 1.1E-6 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_27740 a443986578712323b3fa4fd2e0ecf931 233 Pfam PF12840 Helix-turn-helix domain 36 91 5.6E-13 T 12-10-2018 UA74_25115 2e5b1ad22ccadfdd637ebeeaf48785c2 311 Gene3D G3DSA:1.20.120.350 4 116 6.5E-29 T 12-10-2018 IPR027359 Voltage-dependent channel domain superfamily UA74_25115 2e5b1ad22ccadfdd637ebeeaf48785c2 311 Gene3D G3DSA:1.10.287.70 117 214 1.5E-30 T 12-10-2018 UA74_25115 2e5b1ad22ccadfdd637ebeeaf48785c2 311 Pfam PF00520 Ion transport protein 14 225 1.1E-45 T 12-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 UA74_25115 2e5b1ad22ccadfdd637ebeeaf48785c2 311 SUPERFAMILY SSF81324 13 223 3.14E-35 T 12-10-2018 UA74_12665 80a73c8d2decd138816170aacdd75f81 454 Pfam PF00324 Amino acid permease 29 381 1.5E-36 T 12-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UA74_12665 80a73c8d2decd138816170aacdd75f81 454 PIRSF PIRSF006060 6 439 1.9E-67 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UA74_12665 80a73c8d2decd138816170aacdd75f81 454 Gene3D G3DSA:1.20.1740.10 19 443 4.9E-75 T 12-10-2018 UA74_18670 e7aae6872ed6e43b438e328cd0a10df1 149 Pfam PF04075 F420H(2)-dependent quinone reductase 14 141 1.1E-32 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_18670 e7aae6872ed6e43b438e328cd0a10df1 149 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 30 141 1.9E-27 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_18670 e7aae6872ed6e43b438e328cd0a10df1 149 SUPERFAMILY SSF50475 29 145 1.91E-5 T 12-10-2018 UA74_18670 e7aae6872ed6e43b438e328cd0a10df1 149 Gene3D G3DSA:2.30.110.10 2 142 4.5E-37 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_28955 0ce464af3f88728cad21680416131f75 287 SUPERFAMILY SSF51197 130 283 3.61E-14 T 12-10-2018 UA74_28955 0ce464af3f88728cad21680416131f75 287 Gene3D G3DSA:3.60.130.10 63 286 3.8E-16 T 12-10-2018 UA74_07560 0f7c7c90cd79848dfb21a462b3f8bf46 108 Pfam PF02426 Muconolactone delta-isomerase 1 89 1.4E-15 T 12-10-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 UA74_07560 0f7c7c90cd79848dfb21a462b3f8bf46 108 Gene3D G3DSA:3.30.70.1060 1 94 2.9E-14 T 12-10-2018 UA74_07560 0f7c7c90cd79848dfb21a462b3f8bf46 108 SUPERFAMILY SSF54909 1 95 5.36E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_13935 95a112835980962431d836ba671ccef4 606 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 456 4.8E-87 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_13935 95a112835980962431d836ba671ccef4 606 PIRSF PIRSF002741 4 553 2.3E-93 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_13935 95a112835980962431d836ba671ccef4 606 Gene3D G3DSA:3.10.105.10 299 521 2.6E-50 T 12-10-2018 UA74_13935 95a112835980962431d836ba671ccef4 606 Gene3D G3DSA:3.40.190.10 12 289 1.7E-70 T 12-10-2018 UA74_13935 95a112835980962431d836ba671ccef4 606 SUPERFAMILY SSF53850 36 547 2.71E-124 T 12-10-2018 UA74_13760 43e789c53b98e8c81efb155f00389c12 163 Gene3D G3DSA:3.30.530.20 1 160 1.9E-18 T 12-10-2018 IPR023393 START-like domain superfamily UA74_13760 43e789c53b98e8c81efb155f00389c12 163 SUPERFAMILY SSF55961 1 156 2.42E-21 T 12-10-2018 UA74_13760 43e789c53b98e8c81efb155f00389c12 163 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 150 6.5E-8 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase UA74_20955 ecadac03cd3f7f326745c3638c3e4f36 146 SUPERFAMILY SSF46785 6 135 6.14E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20955 ecadac03cd3f7f326745c3638c3e4f36 146 Gene3D G3DSA:1.10.10.10 2 137 9.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_22470 248619386c0b69306cc3f04b1cb66d25 416 Pfam PF14559 Tetratricopeptide repeat 12 69 2.5E-7 T 12-10-2018 UA74_22470 248619386c0b69306cc3f04b1cb66d25 416 Gene3D G3DSA:3.40.50.300 133 384 2.4E-82 T 12-10-2018 UA74_22470 248619386c0b69306cc3f04b1cb66d25 416 Gene3D G3DSA:1.10.8.60 305 379 2.4E-82 T 12-10-2018 UA74_22470 248619386c0b69306cc3f04b1cb66d25 416 SMART SM00382 169 306 1.5E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_22470 248619386c0b69306cc3f04b1cb66d25 416 ProSitePatterns PS00674 AAA-protein family signature. 274 292 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 UA74_22470 248619386c0b69306cc3f04b1cb66d25 416 Gene3D G3DSA:1.25.40.10 4 73 6.3E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_22470 248619386c0b69306cc3f04b1cb66d25 416 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 173 302 2.9E-43 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_22470 248619386c0b69306cc3f04b1cb66d25 416 SUPERFAMILY SSF52540 133 383 2.61E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00240 81dbb3917c576e17fc06ec4a5518cda6 248 Gene3D G3DSA:2.60.40.2230 29 188 1.4E-49 T 12-10-2018 IPR038507 YcnI-like superfamily UA74_00240 81dbb3917c576e17fc06ec4a5518cda6 248 Pfam PF07987 Domain of unkown function (DUF1775) 31 174 4.9E-39 T 12-10-2018 IPR012533 YcnI-like UA74_09110 0b81a0887e66684ce570098cf8461c55 129 Gene3D G3DSA:1.10.1660.10 1 120 2.8E-26 T 12-10-2018 UA74_09110 0b81a0887e66684ce570098cf8461c55 129 SUPERFAMILY SSF46955 1 113 1.03E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_09110 0b81a0887e66684ce570098cf8461c55 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09110 0b81a0887e66684ce570098cf8461c55 129 SMART SM00422 1 69 4.4E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09110 0b81a0887e66684ce570098cf8461c55 129 Pfam PF13411 MerR HTH family regulatory protein 1 63 1.1E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09110 0b81a0887e66684ce570098cf8461c55 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.7E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09110 0b81a0887e66684ce570098cf8461c55 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.7E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_09110 0b81a0887e66684ce570098cf8461c55 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.7E-7 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_13455 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 7.9E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_13455 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 7.9E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_13455 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 7.9E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_13455 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 7.9E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_13455 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 SUPERFAMILY SSF46785 24 154 1.12E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_13455 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 Gene3D G3DSA:1.10.10.10 18 158 1.1E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13455 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 Pfam PF01047 MarR family 54 104 2.3E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_13455 9c8e4f5c5ed1d3bd4a43fa94adc2a50a 165 SMART SM00347 40 140 4.5E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_11055 2442b594c7527bafee319adf19061657 206 SUPERFAMILY SSF46785 10 187 9.86E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_11055 2442b594c7527bafee319adf19061657 206 Gene3D G3DSA:1.10.10.10 2 117 1.7E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_11055 2442b594c7527bafee319adf19061657 206 Pfam PF03551 Transcriptional regulator PadR-like family 14 89 6.7E-13 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_29105 af305b1c42d5ee03729673b30848335d 346 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 338 4.7E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_29105 af305b1c42d5ee03729673b30848335d 346 Gene3D G3DSA:1.10.3720.10 100 341 1.7E-27 T 12-10-2018 IPR035906 MetI-like superfamily UA74_29105 af305b1c42d5ee03729673b30848335d 346 SUPERFAMILY SSF161098 67 335 6.54E-28 T 12-10-2018 IPR035906 MetI-like superfamily UA74_29105 af305b1c42d5ee03729673b30848335d 346 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 44 340 1.3E-83 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 UA74_07360 4e3d025e21a34c9eb3a60eb8da9b0f34 447 SUPERFAMILY SSF47413 47 114 2.7E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_07360 4e3d025e21a34c9eb3a60eb8da9b0f34 447 SMART SM00530 55 111 7.8E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_07360 4e3d025e21a34c9eb3a60eb8da9b0f34 447 Gene3D G3DSA:1.10.260.40 48 132 3.9E-13 T 12-10-2018 UA74_07360 4e3d025e21a34c9eb3a60eb8da9b0f34 447 Pfam PF13560 Helix-turn-helix domain 52 110 3.1E-11 T 12-10-2018 UA74_08605 1a03904eb674f630303c43cb1fedb4db 246 SUPERFAMILY SSF53213 5 244 1.96E-8 T 12-10-2018 UA74_08605 1a03904eb674f630303c43cb1fedb4db 246 Gene3D G3DSA:3.40.830.10 91 244 2.6E-21 T 12-10-2018 UA74_00235 efe22ead510f0e1d514e630b36b2f0a9 189 SUPERFAMILY SSF81296 29 124 5.04E-23 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_00235 efe22ead510f0e1d514e630b36b2f0a9 189 Pfam PF04234 CopC domain 30 123 1.3E-23 T 12-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 UA74_00235 efe22ead510f0e1d514e630b36b2f0a9 189 Gene3D G3DSA:2.60.40.1220 30 128 1.3E-24 T 12-10-2018 UA74_14485 cc8aca53116517a4931339586f9bb6be 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 40 1.2E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_14485 cc8aca53116517a4931339586f9bb6be 285 SUPERFAMILY SSF46785 2 59 1.66E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14485 cc8aca53116517a4931339586f9bb6be 285 Pfam PF03466 LysR substrate binding domain 66 271 1.6E-26 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_14485 cc8aca53116517a4931339586f9bb6be 285 SUPERFAMILY SSF53850 66 277 2.01E-28 T 12-10-2018 UA74_14485 cc8aca53116517a4931339586f9bb6be 285 Gene3D G3DSA:1.10.10.10 1 65 9.0E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14485 cc8aca53116517a4931339586f9bb6be 285 Gene3D G3DSA:3.40.190.10 70 267 2.7E-40 T 12-10-2018 UA74_14485 cc8aca53116517a4931339586f9bb6be 285 Gene3D G3DSA:3.40.190.10 140 249 2.7E-40 T 12-10-2018 UA74_04285 98ce6cf4a60c99d1a6bd8cce3114df3f 356 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_04285 98ce6cf4a60c99d1a6bd8cce3114df3f 356 SUPERFAMILY SSF52540 4 240 3.87E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04285 98ce6cf4a60c99d1a6bd8cce3114df3f 356 Gene3D G3DSA:3.40.50.300 2 249 1.9E-71 T 12-10-2018 UA74_04285 98ce6cf4a60c99d1a6bd8cce3114df3f 356 Pfam PF00005 ABC transporter 19 160 1.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_04285 98ce6cf4a60c99d1a6bd8cce3114df3f 356 SMART SM00382 27 210 4.5E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_15460 7bc26048e5ab58852cc3287b7a0e77ec 226 Pfam PF01061 ABC-2 type transporter 2 180 2.4E-18 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_15460 7bc26048e5ab58852cc3287b7a0e77ec 226 PIRSF PIRSF006648 1 226 1.8E-57 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_14985 12850abd79524eda784c4712acebb263 178 Pfam PF13302 Acetyltransferase (GNAT) domain 14 154 2.6E-22 T 12-10-2018 IPR000182 GNAT domain UA74_14985 12850abd79524eda784c4712acebb263 178 SUPERFAMILY SSF55729 9 156 3.87E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_14985 12850abd79524eda784c4712acebb263 178 Gene3D G3DSA:3.40.630.30 2 164 3.0E-34 T 12-10-2018 UA74_17820 0929005503b4c7c15d0df6bf2c159da2 202 Gene3D G3DSA:1.10.357.10 11 201 1.8E-52 T 12-10-2018 UA74_17820 0929005503b4c7c15d0df6bf2c159da2 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 69 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_17820 0929005503b4c7c15d0df6bf2c159da2 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 1.2E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_17820 0929005503b4c7c15d0df6bf2c159da2 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 7.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_17820 0929005503b4c7c15d0df6bf2c159da2 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 7.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_17820 0929005503b4c7c15d0df6bf2c159da2 202 SUPERFAMILY SSF46689 14 90 2.54E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_17820 0929005503b4c7c15d0df6bf2c159da2 202 SUPERFAMILY SSF48498 92 199 7.71E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_11090 3032acea31975d3b4957a188eac25d11 146 SMART SM01323 1 83 5.7E-29 T 12-10-2018 IPR003849 Preprotein translocase YajC UA74_11090 3032acea31975d3b4957a188eac25d11 146 Pfam PF02699 Preprotein translocase subunit 5 80 4.9E-21 T 12-10-2018 IPR003849 Preprotein translocase YajC UA74_11090 3032acea31975d3b4957a188eac25d11 146 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 82 3.6E-22 T 12-10-2018 IPR003849 Preprotein translocase YajC UA74_09720 7668335c053980b4947dbc302857895a 1054 Gene3D G3DSA:3.40.50.620 26 640 5.4E-228 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_09720 7668335c053980b4947dbc302857895a 1054 SUPERFAMILY SSF47323 669 908 5.05E-42 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_09720 7668335c053980b4947dbc302857895a 1054 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 18 861 6.5E-242 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_09720 7668335c053980b4947dbc302857895a 1054 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 63 74 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_09720 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 236 259 1.7E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_09720 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 404 419 1.7E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_09720 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 56 67 1.7E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_09720 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 573 582 1.7E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_09720 7668335c053980b4947dbc302857895a 1054 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 533 546 1.7E-30 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UA74_09720 7668335c053980b4947dbc302857895a 1054 SUPERFAMILY SSF50677 217 406 5.55E-50 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_09720 7668335c053980b4947dbc302857895a 1054 SUPERFAMILY SSF52374 20 647 6.17E-123 T 12-10-2018 UA74_09720 7668335c053980b4947dbc302857895a 1054 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 648 3.0E-183 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_09720 7668335c053980b4947dbc302857895a 1054 Gene3D G3DSA:3.90.740.10 214 410 5.4E-228 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UA74_09720 7668335c053980b4947dbc302857895a 1054 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 14 1053 13.828 T 12-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UA74_09720 7668335c053980b4947dbc302857895a 1054 Gene3D G3DSA:1.10.730.10 656 841 3.5E-38 T 12-10-2018 UA74_09720 7668335c053980b4947dbc302857895a 1054 Pfam PF08264 Anticodon-binding domain of tRNA 710 849 5.1E-20 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 UA74_07190 576ce43412407590c77d531bad25467d 291 SUPERFAMILY SSF56235 8 204 2.85E-47 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_07190 576ce43412407590c77d531bad25467d 291 Pfam PF06267 Family of unknown function (DUF1028) 8 193 1.5E-47 T 12-10-2018 IPR010430 Protein of unknown function DUF1028 UA74_07190 576ce43412407590c77d531bad25467d 291 Gene3D G3DSA:3.60.20.10 5 218 4.2E-53 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_26260 83f8900dd22ca65b1626ed934382db35 410 Pfam PF00005 ABC transporter 24 162 2.4E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_26260 83f8900dd22ca65b1626ed934382db35 410 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_26260 83f8900dd22ca65b1626ed934382db35 410 SUPERFAMILY SSF52540 5 225 8.22E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26260 83f8900dd22ca65b1626ed934382db35 410 Gene3D G3DSA:3.40.50.300 2 235 2.0E-55 T 12-10-2018 UA74_26260 83f8900dd22ca65b1626ed934382db35 410 SMART SM00382 32 210 7.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_25565 6960d475ec7d590edfd91acb2d43ac91 218 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 6 208 29.941 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 UA74_25565 6960d475ec7d590edfd91acb2d43ac91 218 Pfam PF02669 K+-transporting ATPase, c chain 11 205 1.1E-55 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 UA74_25565 6960d475ec7d590edfd91acb2d43ac91 218 PIRSF PIRSF001296 5 212 9.9E-55 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 UA74_06590 658af1d6540254c9d3680a864cc71faa 269 Gene3D G3DSA:1.10.10.10 19 95 1.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_06590 658af1d6540254c9d3680a864cc71faa 269 Pfam PF09339 IclR helix-turn-helix domain 24 73 9.7E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_06590 658af1d6540254c9d3680a864cc71faa 269 Gene3D G3DSA:3.30.450.40 97 268 3.8E-54 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_06590 658af1d6540254c9d3680a864cc71faa 269 Pfam PF01614 Bacterial transcriptional regulator 140 262 3.2E-34 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_06590 658af1d6540254c9d3680a864cc71faa 269 SUPERFAMILY SSF46785 22 93 2.66E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_06590 658af1d6540254c9d3680a864cc71faa 269 SUPERFAMILY SSF55781 79 266 3.4E-50 T 12-10-2018 UA74_06590 658af1d6540254c9d3680a864cc71faa 269 SMART SM00346 22 111 6.0E-21 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_07500 87864baa37573efc284b044a195febce 477 Gene3D G3DSA:3.90.1200.10 221 471 1.7E-87 T 12-10-2018 UA74_07500 87864baa37573efc284b044a195febce 477 SUPERFAMILY SSF56112 149 436 6.73E-16 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_07500 87864baa37573efc284b044a195febce 477 Pfam PF01636 Phosphotransferase enzyme family 148 381 4.5E-5 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_23275 b80ad5f105686171ec395ee75150797f 388 Pfam PF07730 Histidine kinase 189 254 2.8E-18 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_23275 b80ad5f105686171ec395ee75150797f 388 SUPERFAMILY SSF55874 277 383 1.29E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_23275 b80ad5f105686171ec395ee75150797f 388 Gene3D G3DSA:3.30.565.10 263 384 6.8E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_23445 63fd36251f01425635a47850b4f7e2aa 187 SUPERFAMILY SSF55874 91 174 4.86E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_23445 63fd36251f01425635a47850b4f7e2aa 187 Gene3D G3DSA:3.30.565.10 54 186 2.6E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_23445 63fd36251f01425635a47850b4f7e2aa 187 Pfam PF13581 Histidine kinase-like ATPase domain 69 173 5.7E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_07215 bfac134f9b9a7321646b6560c13573dd 111 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 92 6.7E-27 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane UA74_07215 bfac134f9b9a7321646b6560c13573dd 111 Pfam PF12823 Domain of unknown function (DUF3817) 7 94 1.7E-26 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane UA74_30025 ee5f76a22a1be3f5a6df447c79b65879 454 Pfam PF03796 DnaB-like helicase C terminal domain 196 449 1.2E-101 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 UA74_30025 ee5f76a22a1be3f5a6df447c79b65879 454 Gene3D G3DSA:3.40.50.300 179 454 2.3E-101 T 12-10-2018 UA74_30025 ee5f76a22a1be3f5a6df447c79b65879 454 Gene3D G3DSA:1.10.860.10 11 177 5.1E-60 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal UA74_30025 ee5f76a22a1be3f5a6df447c79b65879 454 SMART SM00382 213 410 9.1E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_30025 ee5f76a22a1be3f5a6df447c79b65879 454 Pfam PF00772 DnaB-like helicase N terminal domain 18 120 3.4E-34 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 UA74_30025 ee5f76a22a1be3f5a6df447c79b65879 454 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 19 452 3.4E-162 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 UA74_30025 ee5f76a22a1be3f5a6df447c79b65879 454 SUPERFAMILY SSF48024 17 128 7.45E-38 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 UA74_30025 ee5f76a22a1be3f5a6df447c79b65879 454 SUPERFAMILY SSF52540 196 439 3.09E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14050 1b269a1e8670b74f2e5bed8409eca1fd 271 Pfam PF13349 Putative adhesin 140 244 3.0E-8 T 12-10-2018 IPR025164 Putative adhesin UA74_21305 0234b70e2600b2e5ff665bd5115318ab 315 Pfam PF04018 Domain of unknown function (DUF368) 2 246 4.8E-65 T 12-10-2018 IPR007163 Protein of unknown function DUF368 UA74_25090 8f50fdc6817cbdfdc6f3992258624a69 292 Gene3D G3DSA:3.40.50.720 1 288 1.2E-78 T 12-10-2018 UA74_25090 8f50fdc6817cbdfdc6f3992258624a69 292 SUPERFAMILY SSF51735 1 239 1.54E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25090 8f50fdc6817cbdfdc6f3992258624a69 292 Pfam PF00106 short chain dehydrogenase 1 203 6.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_23515 a5f09569f275d0a9bcb2b71b96204bd8 277 PIRSF PIRSF015736 31 272 2.1E-59 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase UA74_23515 a5f09569f275d0a9bcb2b71b96204bd8 277 Gene3D G3DSA:3.40.50.12500 40 272 9.0E-59 T 12-10-2018 UA74_01505 d598d53332670bb2384a62816a33c445 172 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 31.785 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 UA74_01505 d598d53332670bb2384a62816a33c445 172 Gene3D G3DSA:3.90.80.10 1 161 3.2E-64 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 UA74_01505 d598d53332670bb2384a62816a33c445 172 Pfam PF00719 Inorganic pyrophosphatase 5 156 2.2E-52 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 UA74_01505 d598d53332670bb2384a62816a33c445 172 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 UA74_01505 d598d53332670bb2384a62816a33c445 172 SUPERFAMILY SSF50324 3 157 4.58E-55 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 UA74_10325 c81d38b7c4852ad0ff6636ecba0b9a70 388 Pfam PF00266 Aminotransferase class-V 50 371 2.3E-32 T 12-10-2018 IPR000192 Aminotransferase class V domain UA74_10325 c81d38b7c4852ad0ff6636ecba0b9a70 388 Gene3D G3DSA:3.90.1150.10 24 378 2.4E-92 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_10325 c81d38b7c4852ad0ff6636ecba0b9a70 388 PIRSF PIRSF000524 15 388 1.2E-72 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 UA74_10325 c81d38b7c4852ad0ff6636ecba0b9a70 388 SUPERFAMILY SSF53383 24 384 3.75E-78 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_10325 c81d38b7c4852ad0ff6636ecba0b9a70 388 Gene3D G3DSA:3.40.640.10 32 281 2.4E-92 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_12050 10c0f0681bd469cbad01171bee7c731f 178 SMART SM00732 27 129 6.2E-21 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 UA74_12050 10c0f0681bd469cbad01171bee7c731f 178 Pfam PF03652 Holliday junction resolvase 28 161 1.4E-41 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 UA74_12050 10c0f0681bd469cbad01171bee7c731f 178 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 30 161 4.7E-26 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 UA74_12050 10c0f0681bd469cbad01171bee7c731f 178 Gene3D G3DSA:3.30.420.140 28 171 1.0E-42 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 UA74_12050 10c0f0681bd469cbad01171bee7c731f 178 SUPERFAMILY SSF53098 27 163 3.19E-32 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_12050 10c0f0681bd469cbad01171bee7c731f 178 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 27 164 21.948 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 UA74_03440 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Gene3D G3DSA:2.20.230.10 198 284 4.5E-24 T 12-10-2018 UA74_03440 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Pfam PF06737 Transglycosylase-like domain 287 363 3.3E-24 T 12-10-2018 IPR010618 Transglycosylase-like UA74_03440 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Gene3D G3DSA:1.10.530.10 287 369 7.0E-28 T 12-10-2018 UA74_03440 5f0b3045da0ae36b7fadf20ac0b0ced4 371 SMART SM01208 200 278 1.3E-27 T 12-10-2018 IPR011098 G5 domain UA74_03440 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Pfam PF03990 Domain of unknown function (DUF348) 32 72 1.6E-12 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 UA74_03440 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Pfam PF03990 Domain of unknown function (DUF348) 148 187 9.8E-9 T 12-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 UA74_03440 5f0b3045da0ae36b7fadf20ac0b0ced4 371 SUPERFAMILY SSF53955 286 369 1.87E-24 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_03440 5f0b3045da0ae36b7fadf20ac0b0ced4 371 Pfam PF07501 G5 domain 204 277 3.7E-24 T 12-10-2018 IPR011098 G5 domain UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 Gene3D G3DSA:3.40.190.10 103 276 2.1E-13 T 12-10-2018 UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.0E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 SUPERFAMILY SSF53850 89 283 9.23E-15 T 12-10-2018 UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 8.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 8.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 8.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 Gene3D G3DSA:1.10.10.10 1 89 1.5E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 Gene3D G3DSA:3.40.190.10 166 258 2.1E-13 T 12-10-2018 UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 Pfam PF03466 LysR substrate binding domain 89 279 4.0E-10 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_13645 ad90aebe9aeb26b099aef83dd1024a3a 297 SUPERFAMILY SSF46785 5 88 1.96E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_17175 d77af151171f05b619564440664dedb6 277 Gene3D G3DSA:3.40.50.300 2 252 3.8E-61 T 12-10-2018 UA74_17175 d77af151171f05b619564440664dedb6 277 SMART SM00382 27 212 5.5E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_17175 d77af151171f05b619564440664dedb6 277 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_17175 d77af151171f05b619564440664dedb6 277 Pfam PF00005 ABC transporter 20 167 4.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_17175 d77af151171f05b619564440664dedb6 277 SUPERFAMILY SSF52540 3 224 1.67E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10910 1c3093120e24c70d2cb2957b7e3e19f9 493 Pfam PF00999 Sodium/hydrogen exchanger family 77 463 9.8E-51 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 UA74_10910 1c3093120e24c70d2cb2957b7e3e19f9 493 Gene3D G3DSA:1.20.1530.20 69 470 9.1E-89 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily UA74_26825 f9859b290c6676438125e18cb04fd2d3 840 Gene3D G3DSA:1.10.287.1060 25 119 1.1E-6 T 12-10-2018 UA74_26825 f9859b290c6676438125e18cb04fd2d3 840 Pfam PF14021 Tuberculosis necrotizing toxin 733 816 1.3E-26 T 12-10-2018 IPR025331 Tuberculosis necrotizing toxin KEGG: 00760+3.2.2.5 UA74_01945 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 145 162 3.0E-19 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01945 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 164 187 3.0E-19 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01945 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 124 144 3.0E-19 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01945 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 65 79 3.0E-19 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01945 11bc50af06ed805c47261def5cdb1b5c 220 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 188 202 3.0E-19 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01945 11bc50af06ed805c47261def5cdb1b5c 220 Gene3D G3DSA:2.40.10.10 112 205 1.1E-49 T 12-10-2018 UA74_01945 11bc50af06ed805c47261def5cdb1b5c 220 Gene3D G3DSA:2.40.10.10 45 216 1.1E-49 T 12-10-2018 UA74_01945 11bc50af06ed805c47261def5cdb1b5c 220 SUPERFAMILY SSF50494 44 213 3.39E-26 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_22835 59137390bad494f275962703ad80ac94 337 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 250 337 1.2E-26 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_22835 59137390bad494f275962703ad80ac94 337 Gene3D G3DSA:3.40.47.10 16 337 7.0E-108 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_22835 59137390bad494f275962703ad80ac94 337 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 121 193 5.8E-21 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UA74_22835 59137390bad494f275962703ad80ac94 337 SUPERFAMILY SSF53901 16 337 5.47E-54 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Pfam PF04542 Sigma-70 region 2 54 124 5.5E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 269 6.2E-40 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Gene3D G3DSA:1.10.10.10 201 271 1.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 PRINTS PR00046 Major sigma-70 factor signature 255 266 1.4E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 PRINTS PR00046 Major sigma-70 factor signature 223 235 1.4E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 PRINTS PR00046 Major sigma-70 factor signature 240 255 1.4E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 PRINTS PR00046 Major sigma-70 factor signature 78 91 1.4E-9 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 48 270 1.6E-90 T 12-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Pfam PF04539 Sigma-70 region 3 138 192 1.1E-11 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 SUPERFAMILY SSF88659 127 200 6.1E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Gene3D G3DSA:1.20.120.1810 14 122 1.1E-20 T 12-10-2018 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 SUPERFAMILY SSF88946 31 124 6.67E-31 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Gene3D G3DSA:1.10.10.10 123 176 1.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 Pfam PF04545 Sigma-70, region 4 219 268 4.4E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UA74_21285 14bf66febbf96b2aa3d0f7b5c3b1e5f9 271 SUPERFAMILY SSF88659 203 269 2.62E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_18160 2ffc375e41ff105b1bec7bafc190b152 264 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 146 1.7E-24 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_18160 2ffc375e41ff105b1bec7bafc190b152 264 SUPERFAMILY SSF102588 3 223 1.7E-51 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_18160 2ffc375e41ff105b1bec7bafc190b152 264 Gene3D G3DSA:3.40.50.10320 2 264 2.1E-69 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_26305 e517973d46bdb1b84115b3ddfcb671fa 450 Gene3D G3DSA:2.30.40.10 21 429 3.7E-135 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_26305 e517973d46bdb1b84115b3ddfcb671fa 450 SUPERFAMILY SSF51556 53 376 8.81E-64 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_26305 e517973d46bdb1b84115b3ddfcb671fa 450 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 17 447 7.0E-134 T 12-10-2018 IPR010252 Formiminoglutamate deiminase UA74_26305 e517973d46bdb1b84115b3ddfcb671fa 450 Pfam PF01979 Amidohydrolase family 51 424 2.5E-40 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_26305 e517973d46bdb1b84115b3ddfcb671fa 450 SUPERFAMILY SSF51338 356 450 4.32E-15 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_26305 e517973d46bdb1b84115b3ddfcb671fa 450 Gene3D G3DSA:3.20.20.140 55 432 3.7E-135 T 12-10-2018 UA74_07925 708a9ce5db0c80c1a2ab722153ca6bb1 223 Gene3D G3DSA:3.30.40.60 124 198 6.0E-19 T 12-10-2018 UA74_07925 708a9ce5db0c80c1a2ab722153ca6bb1 223 Pfam PF14279 HNH endonuclease 140 186 1.3E-12 T 12-10-2018 IPR029471 HNH endonuclease 5 UA74_07925 708a9ce5db0c80c1a2ab722153ca6bb1 223 SMART SM00507 127 176 9.2E-15 T 12-10-2018 IPR003615 HNH nuclease UA74_19810 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Gene3D G3DSA:2.115.10.20 182 484 5.8E-83 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_19810 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Pfam PF04616 Glycosyl hydrolases family 43 189 475 2.8E-55 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_19810 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 SUPERFAMILY SSF75005 189 490 1.57E-59 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_19810 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 45 118 1.2E-15 T 12-10-2018 IPR000772 Ricin B, lectin domain UA74_19810 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 124 181 3.8E-12 T 12-10-2018 IPR000772 Ricin B, lectin domain UA74_19810 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 SUPERFAMILY SSF50370 41 178 4.19E-40 T 12-10-2018 IPR035992 Ricin B-like lectins UA74_19810 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 SMART SM00458 44 178 7.7E-8 T 12-10-2018 IPR000772 Ricin B, lectin domain UA74_19810 e3cd2ad3daba1e9dd36bdf7c67b9822b 496 Gene3D G3DSA:2.80.10.50 41 181 1.4E-35 T 12-10-2018 UA74_10880 52cc6d5a166bccfe109b193b0f966d6e 510 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 482 1.7E-84 T 12-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 UA74_10880 52cc6d5a166bccfe109b193b0f966d6e 510 Gene3D G3DSA:1.20.1250.20 2 489 1.4E-95 T 12-10-2018 UA74_10880 52cc6d5a166bccfe109b193b0f966d6e 510 SUPERFAMILY SSF103473 200 483 4.19E-13 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_10880 52cc6d5a166bccfe109b193b0f966d6e 510 Pfam PF00854 POT family 94 457 5.6E-33 T 12-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 UA74_10880 52cc6d5a166bccfe109b193b0f966d6e 510 SUPERFAMILY SSF103473 13 202 7.19E-18 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_09705 30528fbffa87350c4b5e077c58afdf6c 205 Gene3D G3DSA:3.30.110.150 115 198 9.0E-27 T 12-10-2018 IPR038594 SepF-like superfamily UA74_09705 30528fbffa87350c4b5e077c58afdf6c 205 Pfam PF04472 Cell division protein SepF 119 190 2.8E-24 T 12-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 UA74_09705 30528fbffa87350c4b5e077c58afdf6c 205 Hamap MF_01197 Cell division protein SepF [sepF]. 1 198 21.761 T 12-10-2018 IPR023052 Cell division protein SepF GO:0090529 UA74_05045 26e2127ed994582e3980f1645a73bb61 462 Gene3D G3DSA:1.10.260.40 2 64 1.9E-11 T 12-10-2018 UA74_05045 26e2127ed994582e3980f1645a73bb61 462 SUPERFAMILY SSF47413 6 62 2.52E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_05045 26e2127ed994582e3980f1645a73bb61 462 SMART SM00530 6 61 3.3E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_05045 26e2127ed994582e3980f1645a73bb61 462 SUPERFAMILY SSF48452 217 326 6.32E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_05045 26e2127ed994582e3980f1645a73bb61 462 Pfam PF13560 Helix-turn-helix domain 9 64 7.7E-8 T 12-10-2018 UA74_05045 26e2127ed994582e3980f1645a73bb61 462 Gene3D G3DSA:1.25.40.10 209 379 2.5E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_29815 c903b42f7bb3b489d3a28626d0c84180 109 Pfam PF01025 GrpE 36 103 2.1E-7 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UA74_29815 c903b42f7bb3b489d3a28626d0c84180 109 Gene3D G3DSA:2.30.22.10 47 109 1.9E-7 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UA74_29815 c903b42f7bb3b489d3a28626d0c84180 109 SUPERFAMILY SSF51064 49 104 3.27E-6 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UA74_06660 2cd7a63a4bedf1d60c2d925e40a191a7 205 SUPERFAMILY SSF48498 90 200 1.67E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_06660 2cd7a63a4bedf1d60c2d925e40a191a7 205 Gene3D G3DSA:1.10.357.10 7 201 1.6E-52 T 12-10-2018 UA74_06660 2cd7a63a4bedf1d60c2d925e40a191a7 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 9.1E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06660 2cd7a63a4bedf1d60c2d925e40a191a7 205 SUPERFAMILY SSF46689 6 85 2.36E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_06660 2cd7a63a4bedf1d60c2d925e40a191a7 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06660 2cd7a63a4bedf1d60c2d925e40a191a7 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.7E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06660 2cd7a63a4bedf1d60c2d925e40a191a7 205 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 91 201 1.4E-18 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal UA74_24570 3eb918ff86586e478eb034f768f0e1ef 267 Gene3D G3DSA:1.10.12.10 200 254 1.3E-16 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal UA74_24570 3eb918ff86586e478eb034f768f0e1ef 267 SUPERFAMILY SSF52096 3 254 2.49E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_24570 3eb918ff86586e478eb034f768f0e1ef 267 Gene3D G3DSA:3.90.226.10 1 195 4.3E-50 T 12-10-2018 UA74_24570 3eb918ff86586e478eb034f768f0e1ef 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 253 4.0E-48 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UA74_18095 dd6856168440055f008ef1966ed9bebd 430 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 225 394 4.1E-32 T 12-10-2018 IPR020051 SagB-type dehydrogenase domain UA74_18095 dd6856168440055f008ef1966ed9bebd 430 Pfam PF00881 Nitroreductase family 210 395 5.4E-13 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_18095 dd6856168440055f008ef1966ed9bebd 430 Gene3D G3DSA:3.40.109.10 177 408 2.5E-57 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_18095 dd6856168440055f008ef1966ed9bebd 430 SUPERFAMILY SSF55469 203 397 2.54E-16 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_19250 7ac09ab47c7fef6285df215f07d48948 182 SUPERFAMILY SSF46689 5 74 2.98E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_19250 7ac09ab47c7fef6285df215f07d48948 182 Gene3D G3DSA:1.10.357.10 2 180 1.5E-21 T 12-10-2018 UA74_19250 7ac09ab47c7fef6285df215f07d48948 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 7.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_23085 c31a243f48078eb8e9cf110603d76384 400 Pfam PF09344 CT1975-like protein 3 376 1.2E-106 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 UA74_23085 c31a243f48078eb8e9cf110603d76384 400 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 3 350 4.6E-87 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 UA74_04230 cebe49da4d0fa9521555c9ad8695ed95 104 Gene3D G3DSA:1.10.287.1060 3 102 1.3E-16 T 12-10-2018 UA74_04230 cebe49da4d0fa9521555c9ad8695ed95 104 Pfam PF06013 Proteins of 100 residues with WXG 5 94 9.7E-7 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like UA74_04230 cebe49da4d0fa9521555c9ad8695ed95 104 SUPERFAMILY SSF140453 5 102 1.02E-8 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_14980 a921f5b5cb2cd7f5fa316bd8a2528e09 172 Gene3D G3DSA:3.30.450.180 7 170 4.5E-13 T 12-10-2018 UA74_28365 85b4ef7cf41052050822ff41e46806e1 288 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 95 236 8.7E-19 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_28365 85b4ef7cf41052050822ff41e46806e1 288 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 80 2.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_28365 85b4ef7cf41052050822ff41e46806e1 288 Gene3D G3DSA:1.10.10.60 27 91 8.4E-26 T 12-10-2018 UA74_28365 85b4ef7cf41052050822ff41e46806e1 288 Gene3D G3DSA:1.10.357.10 93 253 2.4E-35 T 12-10-2018 UA74_28365 85b4ef7cf41052050822ff41e46806e1 288 SUPERFAMILY SSF46689 32 91 3.54E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_28365 85b4ef7cf41052050822ff41e46806e1 288 SUPERFAMILY SSF48498 98 241 7.56E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_08355 c09e62831dd7c873c3ed84cc53f8c088 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 140 5.7E-33 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 UA74_08355 c09e62831dd7c873c3ed84cc53f8c088 141 Gene3D G3DSA:3.50.80.10 1 141 1.8E-37 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily UA74_08355 c09e62831dd7c873c3ed84cc53f8c088 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 27.837 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 UA74_08355 c09e62831dd7c873c3ed84cc53f8c088 141 SUPERFAMILY SSF69500 1 140 1.96E-40 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily UA74_08355 c09e62831dd7c873c3ed84cc53f8c088 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 6.9E-46 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 UA74_06320 8692e7c65035d681da7ef9b02bb234de 199 Gene3D G3DSA:2.60.120.10 29 188 5.0E-19 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_06320 8692e7c65035d681da7ef9b02bb234de 199 SUPERFAMILY SSF51182 51 183 5.69E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_06320 8692e7c65035d681da7ef9b02bb234de 199 Pfam PF05995 Cysteine dioxygenase type I 73 182 2.1E-18 T 12-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 UA74_28835 f4a767426d8665a40e7b652d929164bd 417 SUPERFAMILY SSF53335 60 249 7.04E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_28835 f4a767426d8665a40e7b652d929164bd 417 Pfam PF08484 C-methyltransferase C-terminal domain 244 401 4.1E-58 T 12-10-2018 IPR013691 C-methyltransferase UA74_28835 f4a767426d8665a40e7b652d929164bd 417 Gene3D G3DSA:3.40.50.150 59 255 2.1E-40 T 12-10-2018 UA74_28835 f4a767426d8665a40e7b652d929164bd 417 Gene3D G3DSA:2.20.25.520 1 54 5.7E-15 T 12-10-2018 IPR038576 Methyltransferase putative zinc binding domain superfamily UA74_28835 f4a767426d8665a40e7b652d929164bd 417 Gene3D G3DSA:3.40.50.720 308 413 8.3E-38 T 12-10-2018 UA74_28835 f4a767426d8665a40e7b652d929164bd 417 Pfam PF13489 Methyltransferase domain 79 237 2.1E-11 T 12-10-2018 UA74_28835 f4a767426d8665a40e7b652d929164bd 417 Pfam PF08421 Putative zinc binding domain 3 64 5.1E-20 T 12-10-2018 IPR013630 Methyltransferase putative zinc binding domain UA74_15200 7fdac665a7bef4d23b60a8e8a16b270b 448 Pfam PF04542 Sigma-70 region 2 38 101 2.4E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_15200 7fdac665a7bef4d23b60a8e8a16b270b 448 Pfam PF08281 Sigma-70, region 4 141 189 6.7E-7 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_15200 7fdac665a7bef4d23b60a8e8a16b270b 448 Gene3D G3DSA:1.10.10.10 112 193 5.7E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_15200 7fdac665a7bef4d23b60a8e8a16b270b 448 SUPERFAMILY SSF88946 32 99 3.37E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_15200 7fdac665a7bef4d23b60a8e8a16b270b 448 Gene3D G3DSA:1.10.1740.10 23 99 4.7E-5 T 12-10-2018 UA74_15200 7fdac665a7bef4d23b60a8e8a16b270b 448 SUPERFAMILY SSF88659 131 191 7.29E-9 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_21190 97ee39df702ce77484ae1f8fb86924a1 205 Pfam PF00005 ABC transporter 17 157 5.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_21190 97ee39df702ce77484ae1f8fb86924a1 205 Gene3D G3DSA:3.40.50.300 1 204 2.9E-50 T 12-10-2018 UA74_21190 97ee39df702ce77484ae1f8fb86924a1 205 SMART SM00382 26 205 4.3E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_21190 97ee39df702ce77484ae1f8fb86924a1 205 SUPERFAMILY SSF52540 1 200 2.72E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21190 97ee39df702ce77484ae1f8fb86924a1 205 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 ProSitePatterns PS00902 Glutamate 5-kinase signature. 221 238 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 Gene3D G3DSA:3.40.1160.10 8 276 3.5E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 SUPERFAMILY SSF88697 288 374 1.82E-16 T 12-10-2018 IPR015947 PUA-like superfamily UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 SMART SM00359 288 367 3.3E-16 T 12-10-2018 IPR002478 PUA domain GO:0003723 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 Gene3D G3DSA:2.30.130.10 277 375 1.6E-23 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 PIRSF PIRSF000729 15 376 1.4E-113 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 Hamap MF_00456 Glutamate 5-kinase [proB]. 19 271 34.171 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 SUPERFAMILY SSF53633 19 266 6.41E-55 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 PRINTS PR00474 Glutamate 5-kinase family signature 90 118 8.9E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 PRINTS PR00474 Glutamate 5-kinase family signature 223 243 8.9E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 PRINTS PR00474 Glutamate 5-kinase family signature 162 189 8.9E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 PRINTS PR00474 Glutamate 5-kinase family signature 130 151 8.9E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 PRINTS PR00474 Glutamate 5-kinase family signature 56 70 8.9E-51 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 Pfam PF01472 PUA domain 288 358 7.3E-18 T 12-10-2018 IPR002478 PUA domain GO:0003723 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 Pfam PF00696 Amino acid kinase family 20 247 2.2E-35 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UA74_08220 0c022ee94378aa7f3213ad53b9a1c13b 376 TIGRFAM TIGR01027 proB: glutamate 5-kinase 19 373 1.5E-118 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UA74_30315 08b31e370aa934c3d87f7ace509d8794 106 SUPERFAMILY SSF54211 10 83 1.16E-17 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_30315 08b31e370aa934c3d87f7ace509d8794 106 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 12 82 1.4E-13 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 UA74_30315 08b31e370aa934c3d87f7ace509d8794 106 Pfam PF00825 Ribonuclease P 13 82 4.3E-20 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 UA74_30315 08b31e370aa934c3d87f7ace509d8794 106 Gene3D G3DSA:3.30.230.10 4 88 2.0E-17 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_24455 7c6e054e43b213a87a15ba29afcab8c3 122 Gene3D G3DSA:1.10.10.10 5 122 2.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24455 7c6e054e43b213a87a15ba29afcab8c3 122 SMART SM00345 12 71 1.2E-4 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_24455 7c6e054e43b213a87a15ba29afcab8c3 122 SUPERFAMILY SSF46785 4 84 1.94E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24455 7c6e054e43b213a87a15ba29afcab8c3 122 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.6E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UA74_25265 32fd99bdeeb1b35f1898b6f4e1060055 285 Gene3D G3DSA:3.40.1390.30 8 250 5.4E-61 T 12-10-2018 UA74_25265 32fd99bdeeb1b35f1898b6f4e1060055 285 Gene3D G3DSA:3.40.1390.30 102 238 5.4E-61 T 12-10-2018 UA74_25265 32fd99bdeeb1b35f1898b6f4e1060055 285 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 268 6.3E-46 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 UA74_25265 32fd99bdeeb1b35f1898b6f4e1060055 285 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 7 258 2.1E-63 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 UA74_25265 32fd99bdeeb1b35f1898b6f4e1060055 285 SUPERFAMILY SSF102705 4 276 1.31E-73 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily UA74_07000 e91e216c26c6a49d651b486e50498cba 358 SUPERFAMILY SSF75620 12 351 5.49E-120 T 12-10-2018 UA74_07000 e91e216c26c6a49d651b486e50498cba 358 Pfam PF03462 PCRF domain 12 202 8.3E-62 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 UA74_07000 e91e216c26c6a49d651b486e50498cba 358 Gene3D G3DSA:3.30.160.20 209 295 4.4E-92 T 12-10-2018 UA74_07000 e91e216c26c6a49d651b486e50498cba 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 353 1.5E-143 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 UA74_07000 e91e216c26c6a49d651b486e50498cba 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 2 355 36.765 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 UA74_07000 e91e216c26c6a49d651b486e50498cba 358 Pfam PF00472 RF-1 domain 210 319 8.9E-38 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_07000 e91e216c26c6a49d651b486e50498cba 358 Gene3D G3DSA:3.30.70.1660 106 340 4.4E-92 T 12-10-2018 UA74_07000 e91e216c26c6a49d651b486e50498cba 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_07000 e91e216c26c6a49d651b486e50498cba 358 SMART SM00937 64 177 2.9E-52 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 UA74_23885 86b49b3fc7238dc8ce00000163953796 191 SUPERFAMILY SSF109854 3 135 3.43E-19 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_23885 86b49b3fc7238dc8ce00000163953796 191 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 11 185 7.6E-41 T 12-10-2018 IPR017520 Conserved hypothetical protein CHP03086 UA74_23885 86b49b3fc7238dc8ce00000163953796 191 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 165 7.5E-20 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_23885 86b49b3fc7238dc8ce00000163953796 191 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 7 129 2.0E-12 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_23885 86b49b3fc7238dc8ce00000163953796 191 Gene3D G3DSA:1.20.120.450 3 133 1.8E-10 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_28685 8d6c8514035f7965bcf89ad7c61281e5 497 Gene3D G3DSA:3.40.50.720 146 262 1.9E-17 T 12-10-2018 UA74_28685 8d6c8514035f7965bcf89ad7c61281e5 497 SUPERFAMILY SSF51735 154 455 1.81E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_28685 8d6c8514035f7965bcf89ad7c61281e5 497 Pfam PF00106 short chain dehydrogenase 160 247 7.6E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_28685 8d6c8514035f7965bcf89ad7c61281e5 497 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 342 442 9.4E-7 T 12-10-2018 UA74_28685 8d6c8514035f7965bcf89ad7c61281e5 497 Gene3D G3DSA:3.40.50.720 305 469 5.4E-15 T 12-10-2018 UA74_22765 68567e2292c1e7493bc100e21c04de2c 452 Gene3D G3DSA:1.20.1250.20 22 396 3.3E-39 T 12-10-2018 UA74_22765 68567e2292c1e7493bc100e21c04de2c 452 Pfam PF07690 Major Facilitator Superfamily 26 366 2.1E-29 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_22765 68567e2292c1e7493bc100e21c04de2c 452 SUPERFAMILY SSF103473 18 400 2.75E-50 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_07005 dd0ccc45f562672324292ad5448b1980 280 SUPERFAMILY SSF53335 7 273 7.29E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_07005 dd0ccc45f562672324292ad5448b1980 280 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 18 272 9.2E-65 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 UA74_07005 dd0ccc45f562672324292ad5448b1980 280 Gene3D G3DSA:3.40.50.150 76 279 5.3E-50 T 12-10-2018 UA74_07005 dd0ccc45f562672324292ad5448b1980 280 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 276 37.449 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 UA74_07005 dd0ccc45f562672324292ad5448b1980 280 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 181 187 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_07005 dd0ccc45f562672324292ad5448b1980 280 Gene3D G3DSA:1.10.8.10 1 69 2.1E-12 T 12-10-2018 UA74_07005 dd0ccc45f562672324292ad5448b1980 280 Pfam PF05175 Methyltransferase small domain 103 188 1.9E-12 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 UA74_07005 dd0ccc45f562672324292ad5448b1980 280 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 13 276 8.7E-41 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 UA74_07150 c005c89caa6e4d8fc96b234fe8c18ad4 524 Pfam PF00171 Aldehyde dehydrogenase family 40 490 9.7E-111 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_07150 c005c89caa6e4d8fc96b234fe8c18ad4 524 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 269 276 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UA74_07150 c005c89caa6e4d8fc96b234fe8c18ad4 524 Gene3D G3DSA:3.40.605.10 42 488 1.5E-120 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_07150 c005c89caa6e4d8fc96b234fe8c18ad4 524 SUPERFAMILY SSF53720 31 495 6.68E-114 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_07150 c005c89caa6e4d8fc96b234fe8c18ad4 524 Gene3D G3DSA:3.40.309.10 273 459 1.5E-120 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_00140 9c8f08db3cf790b374fa4b75d8b2e4f5 488 Gene3D G3DSA:3.90.1310.10 58 380 2.7E-137 T 12-10-2018 UA74_00140 9c8f08db3cf790b374fa4b75d8b2e4f5 488 SUPERFAMILY SSF56519 74 119 8.37E-6 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 UA74_00140 9c8f08db3cf790b374fa4b75d8b2e4f5 488 SUPERFAMILY SSF56601 138 483 5.45E-75 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_00140 9c8f08db3cf790b374fa4b75d8b2e4f5 488 Pfam PF00905 Penicillin binding protein transpeptidase domain 157 481 7.3E-66 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_00140 9c8f08db3cf790b374fa4b75d8b2e4f5 488 Gene3D G3DSA:3.40.710.10 137 481 2.7E-137 T 12-10-2018 UA74_18290 e994cfb00d44f69143c43464ad516a82 149 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 31 144 2.0E-27 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 UA74_18290 e994cfb00d44f69143c43464ad516a82 149 Pfam PF03061 Thioesterase superfamily 59 136 1.1E-17 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 UA74_18290 e994cfb00d44f69143c43464ad516a82 149 Gene3D G3DSA:3.10.129.10 2 149 1.9E-44 T 12-10-2018 UA74_18290 e994cfb00d44f69143c43464ad516a82 149 SUPERFAMILY SSF54637 18 144 2.99E-36 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_22920 085310e5cbb4558542ce6884bb6330b9 299 Gene3D G3DSA:1.10.3720.10 27 287 6.6E-46 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22920 085310e5cbb4558542ce6884bb6330b9 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 293 7.2E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_22920 085310e5cbb4558542ce6884bb6330b9 299 SUPERFAMILY SSF161098 31 299 3.79E-58 T 12-10-2018 IPR035906 MetI-like superfamily UA74_12000 b757c7fd526bef520acb69951ed53277 120 Pfam PF07883 Cupin domain 39 96 3.7E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel UA74_12000 b757c7fd526bef520acb69951ed53277 120 SUPERFAMILY SSF51182 3 112 1.07E-22 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_12000 b757c7fd526bef520acb69951ed53277 120 Gene3D G3DSA:2.60.120.10 1 103 6.4E-32 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_05165 24088e80107f4e88d768d3ec13b1f251 346 Pfam PF00487 Fatty acid desaturase 69 305 7.0E-33 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_07905 33430787e94b5b5b1e69649ee3b9550b 447 PRINTS PR01228 Eggshell protein signature 367 385 8.7E-6 T 12-10-2018 UA74_07905 33430787e94b5b5b1e69649ee3b9550b 447 PRINTS PR01228 Eggshell protein signature 229 240 8.7E-6 T 12-10-2018 UA74_07905 33430787e94b5b5b1e69649ee3b9550b 447 PRINTS PR01228 Eggshell protein signature 311 326 8.7E-6 T 12-10-2018 UA74_07905 33430787e94b5b5b1e69649ee3b9550b 447 PRINTS PR01228 Eggshell protein signature 336 346 8.7E-6 T 12-10-2018 UA74_11515 f91dfb8bd18d9d85b180351379812ca5 293 Pfam PF01882 Protein of unknown function DUF58 32 116 4.0E-17 T 12-10-2018 IPR002881 Domain of unknown function DUF58 UA74_19140 951ff6a10f652e6bf5e52f1b4bba6490 125 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 104 1.8E-18 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 UA74_19140 951ff6a10f652e6bf5e52f1b4bba6490 125 Pfam PF03334 Na+/H+ antiporter subunit 13 91 1.8E-19 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 UA74_11535 2e1781bbc000c28a187407c8292dcf14 255 PIRSF PIRSF000094 2 255 8.8E-88 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 UA74_11535 2e1781bbc000c28a187407c8292dcf14 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 2.7E-68 T 12-10-2018 UA74_11535 2e1781bbc000c28a187407c8292dcf14 255 SUPERFAMILY SSF51735 6 253 1.02E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_11535 2e1781bbc000c28a187407c8292dcf14 255 Gene3D G3DSA:3.40.50.720 2 253 1.8E-48 T 12-10-2018 UA74_14250 15380d70c1d0e222f8bf36ee15828bb4 293 Gene3D G3DSA:3.40.830.10 28 293 2.1E-66 T 12-10-2018 UA74_14250 15380d70c1d0e222f8bf36ee15828bb4 293 PIRSF PIRSF006157 34 293 2.3E-71 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 UA74_14250 15380d70c1d0e222f8bf36ee15828bb4 293 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 58 277 1.2E-33 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 UA74_14250 15380d70c1d0e222f8bf36ee15828bb4 293 SUPERFAMILY SSF53213 38 291 2.75E-70 T 12-10-2018 UA74_19165 351d3f714c476b93aba6d24633fd00c8 951 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 785 906 1.1E-30 T 12-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein UA74_19165 351d3f714c476b93aba6d24633fd00c8 951 Pfam PF13244 Domain of unknown function (DUF4040) 601 666 3.2E-16 T 12-10-2018 IPR025383 Domain of unknown function DUF4040 UA74_19165 351d3f714c476b93aba6d24633fd00c8 951 Pfam PF00361 Proton-conducting membrane transporter 126 399 3.0E-66 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_19165 351d3f714c476b93aba6d24633fd00c8 951 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 304 316 9.1E-32 T 12-10-2018 UA74_19165 351d3f714c476b93aba6d24633fd00c8 951 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 9.1E-32 T 12-10-2018 UA74_19165 351d3f714c476b93aba6d24633fd00c8 951 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 76 101 9.1E-32 T 12-10-2018 UA74_19165 351d3f714c476b93aba6d24633fd00c8 951 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 9.1E-32 T 12-10-2018 UA74_19165 351d3f714c476b93aba6d24633fd00c8 951 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 214 235 9.1E-32 T 12-10-2018 UA74_19165 351d3f714c476b93aba6d24633fd00c8 951 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 236 262 9.1E-32 T 12-10-2018 UA74_26000 da4df0b4513e33d37e7e647274b9940c 334 Pfam PF00561 alpha/beta hydrolase fold 25 128 1.4E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_26000 da4df0b4513e33d37e7e647274b9940c 334 SUPERFAMILY SSF53474 4 297 9.51E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26000 da4df0b4513e33d37e7e647274b9940c 334 Gene3D G3DSA:3.40.50.1820 2 299 5.7E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24900 8b7a2bb3c5d9aac7dd3518cbdf255d25 95 SUPERFAMILY SSF54909 2 77 2.95E-16 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_24900 8b7a2bb3c5d9aac7dd3518cbdf255d25 95 Pfam PF01037 Lrp/AsnC ligand binding domain 13 76 1.1E-13 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UA74_24900 8b7a2bb3c5d9aac7dd3518cbdf255d25 95 Gene3D G3DSA:3.30.70.920 1 74 7.5E-17 T 12-10-2018 UA74_12885 4a7a6ece0acf3131b6a84e1639036962 281 Gene3D G3DSA:3.60.20.10 54 281 2.7E-83 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_12885 4a7a6ece0acf3131b6a84e1639036962 281 Hamap MF_02113_B Proteasome subunit beta [prcB]. 10 281 47.352 T 12-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UA74_12885 4a7a6ece0acf3131b6a84e1639036962 281 Pfam PF00227 Proteasome subunit 52 235 4.9E-33 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 UA74_12885 4a7a6ece0acf3131b6a84e1639036962 281 SUPERFAMILY SSF56235 51 265 2.04E-51 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_12885 4a7a6ece0acf3131b6a84e1639036962 281 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 50 275 1.6E-101 T 12-10-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 UA74_20470 f210005b692fced33b759b87c3e8b950 311 SUPERFAMILY SSF46785 8 118 3.48E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20470 f210005b692fced33b759b87c3e8b950 311 Gene3D G3DSA:3.40.190.10 168 273 8.5E-53 T 12-10-2018 UA74_20470 f210005b692fced33b759b87c3e8b950 311 Gene3D G3DSA:3.40.190.10 98 294 8.5E-53 T 12-10-2018 UA74_20470 f210005b692fced33b759b87c3e8b950 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 4.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_20470 f210005b692fced33b759b87c3e8b950 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 4.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_20470 f210005b692fced33b759b87c3e8b950 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 4.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_20470 f210005b692fced33b759b87c3e8b950 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.9E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_20470 f210005b692fced33b759b87c3e8b950 311 SUPERFAMILY SSF53850 96 303 5.97E-32 T 12-10-2018 UA74_20470 f210005b692fced33b759b87c3e8b950 311 Pfam PF03466 LysR substrate binding domain 95 299 2.4E-32 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_20470 f210005b692fced33b759b87c3e8b950 311 Gene3D G3DSA:1.10.10.10 5 89 2.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12365 9e0da9e445e1b996154ec75bd8e3fd10 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 7.0E-6 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_12365 9e0da9e445e1b996154ec75bd8e3fd10 78 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 7.0E-6 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_12365 9e0da9e445e1b996154ec75bd8e3fd10 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 7.0E-6 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_12365 9e0da9e445e1b996154ec75bd8e3fd10 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 4.3E-20 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_12365 9e0da9e445e1b996154ec75bd8e3fd10 78 Pfam PF03840 Preprotein translocase SecG subunit 4 72 2.5E-18 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UA74_23985 9caa3e335929bb0e5bd067fd57d65efa 265 Gene3D G3DSA:3.40.50.300 18 254 4.8E-66 T 12-10-2018 UA74_23985 9caa3e335929bb0e5bd067fd57d65efa 265 SUPERFAMILY SSF52540 21 252 1.46E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_23985 9caa3e335929bb0e5bd067fd57d65efa 265 Pfam PF00005 ABC transporter 41 178 1.6E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_23985 9caa3e335929bb0e5bd067fd57d65efa 265 SMART SM00382 50 229 4.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_23985 9caa3e335929bb0e5bd067fd57d65efa 265 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_21140 d9f46dcb14cfed58ccfb2039c3754368 89 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21140 d9f46dcb14cfed58ccfb2039c3754368 89 PRINTS PR01249 Ribosomal protein L31 signature 45 60 5.5E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21140 d9f46dcb14cfed58ccfb2039c3754368 89 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.5E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21140 d9f46dcb14cfed58ccfb2039c3754368 89 PRINTS PR01249 Ribosomal protein L31 signature 60 78 5.5E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21140 d9f46dcb14cfed58ccfb2039c3754368 89 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 80 6.8E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21140 d9f46dcb14cfed58ccfb2039c3754368 89 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 26.334 T 12-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21140 d9f46dcb14cfed58ccfb2039c3754368 89 Pfam PF01197 Ribosomal protein L31 2 79 3.7E-31 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21140 d9f46dcb14cfed58ccfb2039c3754368 89 Gene3D G3DSA:2.30.170.50 1 83 9.3E-27 T 12-10-2018 UA74_21140 d9f46dcb14cfed58ccfb2039c3754368 89 SUPERFAMILY SSF143800 2 79 7.85E-23 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_22700 57819ac238136f16a9f2cd4f99115615 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 293 1.7E-47 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_22700 57819ac238136f16a9f2cd4f99115615 329 SUPERFAMILY SSF52283 1 128 4.89E-18 T 12-10-2018 UA74_22700 57819ac238136f16a9f2cd4f99115615 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 27 325 2.0E-13 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UA74_22700 57819ac238136f16a9f2cd4f99115615 329 Gene3D G3DSA:3.40.50.720 11 318 3.7E-78 T 12-10-2018 UA74_22700 57819ac238136f16a9f2cd4f99115615 329 Gene3D G3DSA:3.40.50.720 95 292 3.7E-78 T 12-10-2018 UA74_22700 57819ac238136f16a9f2cd4f99115615 329 SUPERFAMILY SSF51735 97 294 1.06E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22700 57819ac238136f16a9f2cd4f99115615 329 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 227 243 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_13275 53a7f0d50eb8d6b956890b839dafd4dc 437 Pfam PF09967 VWA-like domain (DUF2201) 310 432 4.2E-16 T 12-10-2018 IPR018698 VWA-like domain UA74_13275 53a7f0d50eb8d6b956890b839dafd4dc 437 SUPERFAMILY SSF53300 310 420 3.71E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_13275 53a7f0d50eb8d6b956890b839dafd4dc 437 Pfam PF13203 Putative metallopeptidase domain 86 301 2.4E-19 T 12-10-2018 IPR025154 Putative metallopeptidase domain UA74_29720 f311077a06458282047376340cc77d98 761 Pfam PF02754 Cysteine-rich domain 608 694 2.5E-16 T 12-10-2018 IPR004017 Cysteine-rich domain UA74_29720 f311077a06458282047376340cc77d98 761 Pfam PF02754 Cysteine-rich domain 478 569 2.0E-14 T 12-10-2018 IPR004017 Cysteine-rich domain UA74_29720 f311077a06458282047376340cc77d98 761 SUPERFAMILY SSF46548 281 423 1.71E-21 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UA74_29720 f311077a06458282047376340cc77d98 761 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 395 406 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UA74_29720 f311077a06458282047376340cc77d98 761 Pfam PF13183 4Fe-4S dicluster domain 296 409 2.9E-13 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UA74_25105 3a6b49df0174ce112d47d12599210636 156 PIRSF PIRSF021697 1 155 6.1E-44 T 12-10-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane UA74_25105 3a6b49df0174ce112d47d12599210636 156 Pfam PF06271 RDD family 78 149 7.0E-5 T 12-10-2018 IPR010432 RDD UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 293 1.1E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 SUPERFAMILY SSF51905 6 302 1.44E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 2.2E-77 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 2.2E-77 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 2.2E-77 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 253 2.2E-77 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 285 2.2E-77 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 194 210 2.2E-77 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 2.2E-77 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 2.2E-77 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 2.2E-77 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 Gene3D G3DSA:3.50.50.60 7 298 1.2E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 304 6.7E-121 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 Gene3D G3DSA:3.50.50.60 116 238 1.2E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 1.3E-35 T 12-10-2018 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.3E-35 T 12-10-2018 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-35 T 12-10-2018 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 1.3E-35 T 12-10-2018 UA74_30250 b4ea7a6d7597390afd610559cacb2aea 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.3E-35 T 12-10-2018 UA74_09870 b0fbc35e8070240c2f57868d895e31b1 337 SUPERFAMILY SSF56059 142 332 5.71E-13 T 12-10-2018 UA74_09870 b0fbc35e8070240c2f57868d895e31b1 337 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 9 332 2.8E-115 T 12-10-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV-5884 family UA74_09870 b0fbc35e8070240c2f57868d895e31b1 337 Gene3D G3DSA:3.30.470.20 225 334 7.1E-16 T 12-10-2018 UA74_19600 004ef9a96c6fb2db8b10b6c76ec0ea06 291 Gene3D G3DSA:1.10.3470.10 37 273 1.0E-5 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_19600 004ef9a96c6fb2db8b10b6c76ec0ea06 291 SUPERFAMILY SSF81345 2 261 2.35E-36 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_19600 004ef9a96c6fb2db8b10b6c76ec0ea06 291 Pfam PF00950 ABC 3 transport family 11 264 9.5E-65 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UA74_04260 22b8f691f55d1afe51348e9fbb2afcbb 468 Gene3D G3DSA:3.30.565.10 338 461 3.4E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_04260 22b8f691f55d1afe51348e9fbb2afcbb 468 Pfam PF13796 Putative sensor 64 242 2.7E-14 T 12-10-2018 IPR025828 Putative sensor domain UA74_04260 22b8f691f55d1afe51348e9fbb2afcbb 468 Pfam PF07730 Histidine kinase 270 338 3.3E-13 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_04260 22b8f691f55d1afe51348e9fbb2afcbb 468 SUPERFAMILY SSF55874 355 460 1.67E-8 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_26350 ecb56151f14d13e6f63d659ed30bce1d 295 SUPERFAMILY SSF53850 36 293 2.99E-39 T 12-10-2018 UA74_26350 ecb56151f14d13e6f63d659ed30bce1d 295 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 36 293 5.0E-37 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 UA74_26350 ecb56151f14d13e6f63d659ed30bce1d 295 Gene3D G3DSA:3.40.190.120 135 238 3.5E-63 T 12-10-2018 UA74_26350 ecb56151f14d13e6f63d659ed30bce1d 295 Gene3D G3DSA:3.40.190.10 38 292 3.5E-63 T 12-10-2018 UA74_04440 939b15a99f4e251f2f91d4160bec3899 570 Gene3D G3DSA:1.10.287.1060 14 95 7.6E-6 T 12-10-2018 UA74_04440 939b15a99f4e251f2f91d4160bec3899 570 SUPERFAMILY SSF53474 319 501 2.07E-5 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_04440 939b15a99f4e251f2f91d4160bec3899 570 Pfam PF06259 Alpha/beta hydrolase 313 491 1.2E-39 T 12-10-2018 IPR010427 Protein of unknown function DUF1023 UA74_04440 939b15a99f4e251f2f91d4160bec3899 570 SUPERFAMILY SSF140453 12 95 1.83E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_04440 939b15a99f4e251f2f91d4160bec3899 570 Gene3D G3DSA:3.40.50.1820 332 542 9.8E-6 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16585 087a5223da538d7277813f842e02921a 576 Pfam PF00664 ABC transporter transmembrane region 26 286 2.2E-21 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_16585 087a5223da538d7277813f842e02921a 576 SUPERFAMILY SSF52540 321 563 2.02E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16585 087a5223da538d7277813f842e02921a 576 Gene3D G3DSA:1.20.1560.10 1 316 4.1E-34 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_16585 087a5223da538d7277813f842e02921a 576 Gene3D G3DSA:3.40.50.300 326 570 2.1E-80 T 12-10-2018 UA74_16585 087a5223da538d7277813f842e02921a 576 Pfam PF00005 ABC transporter 345 494 1.6E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_16585 087a5223da538d7277813f842e02921a 576 SMART SM00382 354 540 6.4E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_16585 087a5223da538d7277813f842e02921a 576 SUPERFAMILY SSF90123 5 319 3.66E-43 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_16585 087a5223da538d7277813f842e02921a 576 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_07375 dea3b9825514d1730e96da58755bab8c 376 Gene3D G3DSA:3.40.50.150 9 241 3.1E-54 T 12-10-2018 UA74_07375 dea3b9825514d1730e96da58755bab8c 376 SUPERFAMILY SSF53335 11 206 9.77E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_07375 dea3b9825514d1730e96da58755bab8c 376 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 26 205 1.2E-26 T 12-10-2018 UA74_08880 5b7facaafaa75e22c93b0f22e9fe74a6 321 Gene3D G3DSA:1.10.3720.10 93 298 2.9E-18 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08880 5b7facaafaa75e22c93b0f22e9fe74a6 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 306 2.8E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_08880 5b7facaafaa75e22c93b0f22e9fe74a6 321 SUPERFAMILY SSF161098 97 276 5.1E-22 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04715 98b494b2192f1f87520f500c81e27001 76 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 3.9E-30 T 12-10-2018 IPR021456 Protein of unknown function DUF3107 UA74_00200 43d767878c61d7eeae549fc0fc44e311 342 SUPERFAMILY SSF53335 148 333 1.35E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_00200 43d767878c61d7eeae549fc0fc44e311 342 Pfam PF13649 Methyltransferase domain 209 277 1.8E-6 T 12-10-2018 UA74_00200 43d767878c61d7eeae549fc0fc44e311 342 Gene3D G3DSA:3.40.50.150 107 340 6.0E-17 T 12-10-2018 UA74_17065 99e6c65c563aee1f767252b7dc832b2c 303 SUPERFAMILY SSF53167 2 246 1.57E-38 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 UA74_17065 99e6c65c563aee1f767252b7dc832b2c 303 Pfam PF01048 Phosphorylase superfamily 2 242 8.6E-29 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_17065 99e6c65c563aee1f767252b7dc832b2c 303 Gene3D G3DSA:3.40.50.1580 1 250 1.8E-48 T 12-10-2018 UA74_22110 609836439343de19a582c80a16ab0dd0 405 Gene3D G3DSA:1.20.1250.20 4 394 3.7E-40 T 12-10-2018 UA74_22110 609836439343de19a582c80a16ab0dd0 405 SUPERFAMILY SSF103473 7 397 1.7E-46 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_22110 609836439343de19a582c80a16ab0dd0 405 Pfam PF07690 Major Facilitator Superfamily 19 329 1.1E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_17525 c10d24b44ec136d8ebcc635932591397 282 Pfam PF00561 alpha/beta hydrolase fold 26 162 1.2E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_17525 c10d24b44ec136d8ebcc635932591397 282 Gene3D G3DSA:3.40.50.1820 3 278 9.7E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17525 c10d24b44ec136d8ebcc635932591397 282 SUPERFAMILY SSF53474 12 277 5.08E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23955 a087bbf74f6c492ea244cc55d2055b30 424 Gene3D G3DSA:3.30.565.10 292 418 7.8E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_23955 a087bbf74f6c492ea244cc55d2055b30 424 SUPERFAMILY SSF55874 299 417 8.28E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_23955 a087bbf74f6c492ea244cc55d2055b30 424 Pfam PF07730 Histidine kinase 213 276 7.6E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_00610 844cca8006176f6f582bb9c039723e58 387 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 385 2.0E-142 T 12-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain UA74_00610 844cca8006176f6f582bb9c039723e58 387 SUPERFAMILY SSF56059 3 384 2.61E-71 T 12-10-2018 UA74_00610 844cca8006176f6f582bb9c039723e58 387 SUPERFAMILY SSF52440 175 283 1.04E-33 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_00610 844cca8006176f6f582bb9c039723e58 387 Gene3D G3DSA:3.30.1490.330 267 344 1.1E-24 T 12-10-2018 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 2.3E-226 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 59.861 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 134 149 1.1E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 400 413 1.1E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 83 96 1.1E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 287 301 1.1E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 109 117 1.1E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 120 133 1.1E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 210 223 1.1E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 196 209 1.1E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 PRINTS PR00415 Aconitase family signature 344 355 1.1E-46 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 3.9E-154 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 Gene3D G3DSA:3.30.499.20 4 287 2.7E-98 T 12-10-2018 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 Gene3D G3DSA:3.30.499.10 328 467 2.4E-48 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 UA74_25845 46faf31044394d6db3f4aa37fde40cbf 467 SUPERFAMILY SSF53732 2 466 1.83E-161 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 UA74_19330 6767fce064119c1b1d30529efce509a9 319 Pfam PF13354 Beta-lactamase enzyme family 83 288 1.6E-35 T 12-10-2018 UA74_19330 6767fce064119c1b1d30529efce509a9 319 Gene3D G3DSA:3.40.710.10 59 319 8.3E-76 T 12-10-2018 UA74_19330 6767fce064119c1b1d30529efce509a9 319 ProSitePatterns PS00146 Beta-lactamase class-A active site. 95 110 - T 12-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 UA74_19330 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 93 110 3.7E-66 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_19330 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 169 193 3.7E-66 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_19330 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 248 263 3.7E-66 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_19330 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 133 158 3.7E-66 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_19330 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 195 220 3.7E-66 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_19330 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 231 246 3.7E-66 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_19330 6767fce064119c1b1d30529efce509a9 319 PRINTS PR00118 Beta-lactamase class A signature 62 86 3.7E-66 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 UA74_19330 6767fce064119c1b1d30529efce509a9 319 SUPERFAMILY SSF56601 62 310 5.8E-70 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_25425 b751ac2fa109da4ffc6f81aca1773215 82 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 9 82 1.4E-20 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 UA74_25425 b751ac2fa109da4ffc6f81aca1773215 82 Pfam PF00550 Phosphopantetheine attachment site 12 78 7.3E-16 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_25425 b751ac2fa109da4ffc6f81aca1773215 82 SUPERFAMILY SSF47336 7 81 8.77E-21 T 12-10-2018 IPR036736 ACP-like superfamily UA74_25425 b751ac2fa109da4ffc6f81aca1773215 82 Gene3D G3DSA:1.10.1200.10 7 82 1.4E-23 T 12-10-2018 IPR036736 ACP-like superfamily UA74_25425 b751ac2fa109da4ffc6f81aca1773215 82 Hamap MF_01217 Acyl carrier protein [acpP]. 8 82 16.822 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 UA74_25425 b751ac2fa109da4ffc6f81aca1773215 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 45 78 2.0E-9 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 UA74_07530 5aa92eda2cf405fb2c9abb194fd28476 161 Pfam PF12680 SnoaL-like domain 61 154 4.4E-8 T 12-10-2018 IPR037401 SnoaL-like domain UA74_07530 5aa92eda2cf405fb2c9abb194fd28476 161 Gene3D G3DSA:3.10.450.50 50 160 1.1E-12 T 12-10-2018 UA74_07530 5aa92eda2cf405fb2c9abb194fd28476 161 SUPERFAMILY SSF54427 49 155 5.42E-13 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_01480 edacf232b5f83fcdc3f13172f0777a24 1187 SUPERFAMILY SSF89550 5 253 4.12E-30 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UA74_01480 edacf232b5f83fcdc3f13172f0777a24 1187 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1062 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_01480 edacf232b5f83fcdc3f13172f0777a24 1187 SMART SM00481 6 73 2.4E-34 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal UA74_01480 edacf232b5f83fcdc3f13172f0777a24 1187 Pfam PF14579 Helix-hairpin-helix motif 835 924 4.6E-24 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_01480 edacf232b5f83fcdc3f13172f0777a24 1187 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 321 761 8.1E-159 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_01480 edacf232b5f83fcdc3f13172f0777a24 1187 Pfam PF02811 PHP domain 7 199 3.3E-48 T 12-10-2018 IPR004013 PHP domain GO:0003824 UA74_01480 edacf232b5f83fcdc3f13172f0777a24 1187 Gene3D G3DSA:3.20.20.140 2 296 2.9E-95 T 12-10-2018 UA74_01480 edacf232b5f83fcdc3f13172f0777a24 1187 Gene3D G3DSA:1.10.10.1600 454 543 1.4E-15 T 12-10-2018 UA74_18610 60832ee3dd0409f57d13e2863d71db2d 324 Pfam PF08012 Protein of unknown function (DUF1702) 5 318 7.1E-133 T 12-10-2018 IPR012964 Protein of unknown function DUF1702 UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 Gene3D G3DSA:3.40.50.720 3 252 2.0E-77 T 12-10-2018 UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.0E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 SUPERFAMILY SSF51735 10 251 3.78E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_11865 0f09d4be50b5559df263f5a83a683efd 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 249 2.9E-59 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 SUPERFAMILY SSF54211 298 454 2.66E-30 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 326 349 1.2E-83 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 217 245 1.2E-83 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 178 202 1.2E-83 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 85 113 1.2E-83 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 128 145 1.2E-83 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 16 40 1.2E-83 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 PRINTS PR01874 DNA repair protein radA signature 252 278 1.2E-83 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 Gene3D G3DSA:3.30.230.10 315 442 3.7E-13 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 Hamap MF_01498 DNA repair protein RadA [radA]. 27 457 42.352 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 Pfam PF13541 Subunit ChlI of Mg-chelatase 373 432 5.7E-7 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 Pfam PF13481 AAA domain 64 226 1.8E-16 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 SUPERFAMILY SSF52540 75 293 1.61E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 Gene3D G3DSA:3.40.50.300 71 282 3.1E-39 T 12-10-2018 UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 SMART SM00382 93 248 8.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_01660 8a771211ee3141cd2776bb8d84c03e71 460 TIGRFAM TIGR00416 sms: DNA repair protein RadA 10 433 3.0E-152 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 UA74_12215 a7249566d7a00608441a818a1a87df5d 280 SMART SM00934 18 267 5.9E-32 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12215 a7249566d7a00608441a818a1a87df5d 280 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 18 265 2.3E-34 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12215 a7249566d7a00608441a818a1a87df5d 280 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 5 267 1.6E-78 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_12215 a7249566d7a00608441a818a1a87df5d 280 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 92 105 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UA74_12215 a7249566d7a00608441a818a1a87df5d 280 SUPERFAMILY SSF51366 5 268 2.4E-57 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UA74_12215 a7249566d7a00608441a818a1a87df5d 280 Gene3D G3DSA:3.20.20.70 4 277 1.2E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_12215 a7249566d7a00608441a818a1a87df5d 280 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 3 277 32.495 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_04650 e1ed8bbcc8058945004d656bf1593f33 172 SUPERFAMILY SSF88659 94 155 1.57E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_04650 e1ed8bbcc8058945004d656bf1593f33 172 Pfam PF04542 Sigma-70 region 2 7 72 1.4E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_04650 e1ed8bbcc8058945004d656bf1593f33 172 Gene3D G3DSA:1.10.10.10 90 159 1.9E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04650 e1ed8bbcc8058945004d656bf1593f33 172 Gene3D G3DSA:1.10.1740.10 1 75 3.8E-9 T 12-10-2018 UA74_04650 e1ed8bbcc8058945004d656bf1593f33 172 SUPERFAMILY SSF88946 3 78 4.71E-13 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_04650 e1ed8bbcc8058945004d656bf1593f33 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 155 6.4E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_04650 e1ed8bbcc8058945004d656bf1593f33 172 Pfam PF08281 Sigma-70, region 4 100 153 1.1E-17 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_22075 fc8438d30ad33f5df61e2357b5be27b5 191 SUPERFAMILY SSF55729 79 182 3.78E-14 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_22075 fc8438d30ad33f5df61e2357b5be27b5 191 Gene3D G3DSA:3.40.630.30 6 162 5.2E-13 T 12-10-2018 UA74_22075 fc8438d30ad33f5df61e2357b5be27b5 191 Pfam PF13673 Acetyltransferase (GNAT) domain 90 155 1.9E-8 T 12-10-2018 IPR000182 GNAT domain UA74_23790 aeaa3a7fa0c88a4c99596b74a0cc609b 338 SUPERFAMILY SSF161098 93 320 1.57E-52 T 12-10-2018 IPR035906 MetI-like superfamily UA74_23790 aeaa3a7fa0c88a4c99596b74a0cc609b 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 131 320 9.8E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_23790 aeaa3a7fa0c88a4c99596b74a0cc609b 338 SUPERFAMILY SSF160964 51 96 2.35E-5 T 12-10-2018 UA74_23790 aeaa3a7fa0c88a4c99596b74a0cc609b 338 Gene3D G3DSA:1.10.3720.10 89 331 5.0E-65 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20830 c56a4227b24d167d87ed9e54c5464571 751 SMART SM00382 532 660 1.2E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20830 c56a4227b24d167d87ed9e54c5464571 751 SUPERFAMILY SSF52540 487 724 6.62E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20830 c56a4227b24d167d87ed9e54c5464571 751 Gene3D G3DSA:3.40.50.300 471 674 1.6E-38 T 12-10-2018 UA74_20830 c56a4227b24d167d87ed9e54c5464571 751 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 537 661 6.1E-23 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_24170 30813413445a678f50082d8ad3329729 716 Gene3D G3DSA:1.50.10.100 34 383 2.4E-41 T 12-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 UA74_24170 30813413445a678f50082d8ad3329729 716 Gene3D G3DSA:2.70.98.70 459 632 1.3E-10 T 12-10-2018 UA74_24170 30813413445a678f50082d8ad3329729 716 Pfam PF07940 Heparinase II/III-like protein 492 667 9.5E-8 T 12-10-2018 IPR012480 Heparinase II/III-like GO:0016829 UA74_24170 30813413445a678f50082d8ad3329729 716 SUPERFAMILY SSF48230 177 345 4.76E-7 T 12-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 UA74_07035 4edbb72e94b07a3647bdb36ae646dc69 267 Pfam PF00119 ATP synthase A chain 42 259 2.2E-49 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07035 4edbb72e94b07a3647bdb36ae646dc69 267 SUPERFAMILY SSF81336 93 260 4.58E-36 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07035 4edbb72e94b07a3647bdb36ae646dc69 267 Hamap MF_01393 ATP synthase subunit a [atpB]. 19 266 13.52 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07035 4edbb72e94b07a3647bdb36ae646dc69 267 PRINTS PR00123 ATP synthase A subunit signature 184 206 6.3E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07035 4edbb72e94b07a3647bdb36ae646dc69 267 PRINTS PR00123 ATP synthase A subunit signature 246 261 6.3E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07035 4edbb72e94b07a3647bdb36ae646dc69 267 PRINTS PR00123 ATP synthase A subunit signature 99 115 6.3E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07035 4edbb72e94b07a3647bdb36ae646dc69 267 Gene3D G3DSA:1.20.120.220 91 267 1.7E-31 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07035 4edbb72e94b07a3647bdb36ae646dc69 267 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 32 260 3.0E-42 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_16765 64b5a6cb63aa17cecd1a89f1e7633d7e 108 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 8 100 1.7E-7 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 UA74_24535 bc27009a1e47b214e904e16694edb928 243 PIRSF PIRSF000857 5 243 3.7E-88 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 UA74_24535 bc27009a1e47b214e904e16694edb928 243 Gene3D G3DSA:3.40.50.620 29 243 2.4E-62 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_24535 bc27009a1e47b214e904e16694edb928 243 SUPERFAMILY SSF52402 33 207 1.19E-40 T 12-10-2018 UA74_24535 bc27009a1e47b214e904e16694edb928 243 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 37 242 3.8E-54 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 UA74_24535 bc27009a1e47b214e904e16694edb928 243 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 55 241 1.0E-70 T 12-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 UA74_24535 bc27009a1e47b214e904e16694edb928 243 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 54 218 1.3E-40 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 UA74_10860 f11b23acba4090b1878d9f1c4a1252d2 387 Gene3D G3DSA:3.50.50.60 9 361 1.6E-79 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10860 f11b23acba4090b1878d9f1c4a1252d2 387 SUPERFAMILY SSF51905 10 371 1.09E-62 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10860 f11b23acba4090b1878d9f1c4a1252d2 387 Pfam PF01494 FAD binding domain 10 343 4.8E-27 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_10860 f11b23acba4090b1878d9f1c4a1252d2 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 2.5E-19 T 12-10-2018 UA74_10860 f11b23acba4090b1878d9f1c4a1252d2 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 2.5E-19 T 12-10-2018 UA74_10860 f11b23acba4090b1878d9f1c4a1252d2 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 2.5E-19 T 12-10-2018 UA74_10860 f11b23acba4090b1878d9f1c4a1252d2 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 2.5E-19 T 12-10-2018 UA74_15345 59cbf570f85656fcfad1cdf00f0c8a4c 135 SUPERFAMILY SSF54909 21 124 4.56E-22 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_15345 59cbf570f85656fcfad1cdf00f0c8a4c 135 Gene3D G3DSA:3.30.70.1060 1 130 2.2E-25 T 12-10-2018 UA74_15345 59cbf570f85656fcfad1cdf00f0c8a4c 135 Pfam PF03795 YCII-related domain 15 109 5.8E-11 T 12-10-2018 IPR005545 YCII-related UA74_16070 9d085d01192964866d0a707b4e4faf4b 118 SUPERFAMILY SSF47413 26 78 4.57E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_16070 9d085d01192964866d0a707b4e4faf4b 118 Pfam PF01381 Helix-turn-helix 24 77 4.2E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_16070 9d085d01192964866d0a707b4e4faf4b 118 Gene3D G3DSA:1.10.260.40 2 116 1.7E-14 T 12-10-2018 UA74_01995 9be2877e1db4a9440e7116d98c25c893 347 Gene3D G3DSA:3.40.50.10490 197 346 2.2E-34 T 12-10-2018 UA74_01995 9be2877e1db4a9440e7116d98c25c893 347 Pfam PF01380 SIS domain 47 167 1.5E-15 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UA74_01995 9be2877e1db4a9440e7116d98c25c893 347 Pfam PF01380 SIS domain 207 328 1.4E-11 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UA74_01995 9be2877e1db4a9440e7116d98c25c893 347 SUPERFAMILY SSF53697 10 345 1.06E-65 T 12-10-2018 UA74_01995 9be2877e1db4a9440e7116d98c25c893 347 Gene3D G3DSA:3.40.50.10490 5 181 1.4E-41 T 12-10-2018 UA74_01200 6bd3633e7ae86c97a50f6043967229ae 51 Pfam PF13783 Domain of unknown function (DUF4177) 4 38 5.8E-6 T 12-10-2018 IPR025234 Protein of unknown function DUF4177 UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 TIGRFAM TIGR03356 BGL: beta-galactosidase 24 463 9.9E-174 T 12-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 8.2E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 396 407 8.2E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 441 453 8.2E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 375 383 8.2E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 434 8.2E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 28 42 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 Pfam PF00232 Glycosyl hydrolase family 1 23 470 1.8E-147 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 Gene3D G3DSA:3.20.20.80 17 473 4.1E-161 T 12-10-2018 UA74_06755 dc011af702ebbd3124cd3132dc92e18f 480 SUPERFAMILY SSF51445 24 473 9.24E-154 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_01400 08704b608ad3873ef73257c813bf84da 273 Pfam PF00482 Type II secretion system (T2SS), protein F 101 224 9.4E-8 T 12-10-2018 IPR018076 Type II secretion system F domain UA74_23835 2645b7fca6e8f7e6de143d6cb9c1e8d4 434 Pfam PF01547 Bacterial extracellular solute-binding protein 53 340 6.3E-37 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_23835 2645b7fca6e8f7e6de143d6cb9c1e8d4 434 SUPERFAMILY SSF53850 30 432 4.92E-58 T 12-10-2018 UA74_23835 2645b7fca6e8f7e6de143d6cb9c1e8d4 434 Gene3D G3DSA:3.40.190.10 44 380 1.5E-113 T 12-10-2018 UA74_23835 2645b7fca6e8f7e6de143d6cb9c1e8d4 434 Gene3D G3DSA:3.40.190.10 153 423 1.5E-113 T 12-10-2018 UA74_12260 3d0c7b4becd7cfff2b836f8ad8e997e5 255 SUPERFAMILY SSF53335 26 170 6.48E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_12260 3d0c7b4becd7cfff2b836f8ad8e997e5 255 Pfam PF08241 Methyltransferase domain 45 131 1.2E-13 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_12260 3d0c7b4becd7cfff2b836f8ad8e997e5 255 Gene3D G3DSA:3.40.50.150 35 220 1.1E-20 T 12-10-2018 UA74_11510 0dccfd8bc194a4e4e11997740a19dbf0 360 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 56 186 1.4E-58 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 UA74_11510 0dccfd8bc194a4e4e11997740a19dbf0 360 SUPERFAMILY SSF52540 25 307 9.52E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11510 0dccfd8bc194a4e4e11997740a19dbf0 360 Gene3D G3DSA:3.40.50.300 22 218 3.4E-46 T 12-10-2018 UA74_11510 0dccfd8bc194a4e4e11997740a19dbf0 360 Gene3D G3DSA:1.10.8.300 219 332 2.6E-35 T 12-10-2018 UA74_11510 0dccfd8bc194a4e4e11997740a19dbf0 360 PIRSF PIRSF002849 3 337 1.9E-132 T 12-10-2018 UA74_02540 73ee79fe9774b171e595a01d68352eab 390 Pfam PF12146 Serine aminopeptidase, S33 111 202 3.5E-9 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 UA74_02540 73ee79fe9774b171e595a01d68352eab 390 Gene3D G3DSA:3.40.50.1820 64 357 3.7E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_02540 73ee79fe9774b171e595a01d68352eab 390 SUPERFAMILY SSF53474 62 340 1.36E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19480 cbee884f97287f61b28b68b852e13032 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 71 2.2E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19480 cbee884f97287f61b28b68b852e13032 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 2.2E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19480 cbee884f97287f61b28b68b852e13032 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 2.2E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19480 cbee884f97287f61b28b68b852e13032 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 2.2E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19480 cbee884f97287f61b28b68b852e13032 125 Pfam PF01022 Bacterial regulatory protein, arsR family 43 91 1.2E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19480 cbee884f97287f61b28b68b852e13032 125 Gene3D G3DSA:1.10.10.10 18 122 1.3E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19480 cbee884f97287f61b28b68b852e13032 125 SMART SM00418 36 116 8.3E-30 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_19480 cbee884f97287f61b28b68b852e13032 125 SUPERFAMILY SSF46785 24 115 8.06E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_19480 cbee884f97287f61b28b68b852e13032 125 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 62 80 - T 12-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 UA74_29400 cc85787a5956c3fec420e48975b41f94 62 Pfam PF04149 Domain of unknown function (DUF397) 7 58 9.1E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_25410 8446b681accb7467a5bf96806b55c695 402 Gene3D G3DSA:1.10.10.2840 270 397 2.1E-43 T 12-10-2018 UA74_25410 8446b681accb7467a5bf96806b55c695 402 Pfam PF13556 PucR C-terminal helix-turn-helix domain 334 392 2.3E-22 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UA74_28490 c70f147ec408cac1488422f1dc090d28 274 SUPERFAMILY SSF161098 64 246 1.23E-23 T 12-10-2018 IPR035906 MetI-like superfamily UA74_28490 c70f147ec408cac1488422f1dc090d28 274 Gene3D G3DSA:1.10.3720.10 61 257 1.5E-17 T 12-10-2018 IPR035906 MetI-like superfamily UA74_28490 c70f147ec408cac1488422f1dc090d28 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 252 2.9E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_14795 4f288d7e868a232122413f9abb3922fd 74 SUPERFAMILY SSF160582 6 68 3.27E-28 T 12-10-2018 IPR038020 MbtH-like domain superfamily UA74_14795 4f288d7e868a232122413f9abb3922fd 74 Pfam PF03621 MbtH-like protein 6 52 1.3E-22 T 12-10-2018 IPR005153 MbtH-like domain UA74_14795 4f288d7e868a232122413f9abb3922fd 74 SMART SM00923 2 52 4.6E-21 T 12-10-2018 IPR005153 MbtH-like domain UA74_14795 4f288d7e868a232122413f9abb3922fd 74 Gene3D G3DSA:3.90.820.10 3 71 6.0E-32 T 12-10-2018 UA74_24265 9339c54b0e4cf08a86dbcb31b3a42cfe 173 SUPERFAMILY SSF46785 7 167 1.03E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24265 9339c54b0e4cf08a86dbcb31b3a42cfe 173 Pfam PF03551 Transcriptional regulator PadR-like family 10 83 2.7E-9 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_24265 9339c54b0e4cf08a86dbcb31b3a42cfe 173 Gene3D G3DSA:1.10.10.10 4 95 9.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02165 4a1157a957bdf200092064db8a973ec5 273 Gene3D G3DSA:3.40.50.150 23 219 1.1E-7 T 12-10-2018 UA74_02165 4a1157a957bdf200092064db8a973ec5 273 SUPERFAMILY SSF53335 48 185 1.25E-8 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_21620 438114c1f0d85e74d182499213c6d533 406 Gene3D G3DSA:3.40.640.10 62 303 8.1E-141 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_21620 438114c1f0d85e74d182499213c6d533 406 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 18 396 67.294 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 UA74_21620 438114c1f0d85e74d182499213c6d533 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 221 258 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_21620 438114c1f0d85e74d182499213c6d533 406 SUPERFAMILY SSF53383 19 393 3.68E-124 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_21620 438114c1f0d85e74d182499213c6d533 406 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 19 393 3.6E-141 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 UA74_21620 438114c1f0d85e74d182499213c6d533 406 Gene3D G3DSA:3.90.1150.10 28 384 8.1E-141 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_21620 438114c1f0d85e74d182499213c6d533 406 PIRSF PIRSF000521 170 396 5.2E-32 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_21620 438114c1f0d85e74d182499213c6d533 406 PIRSF PIRSF000521 124 158 0.34 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_21620 438114c1f0d85e74d182499213c6d533 406 PIRSF PIRSF000521 15 131 4.0E-9 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_21620 438114c1f0d85e74d182499213c6d533 406 Pfam PF00202 Aminotransferase class-III 26 389 4.2E-110 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_09860 c592440883e0c1e6942ea51ac8399a29 110 SUPERFAMILY SSF46785 4 93 3.57E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_09860 c592440883e0c1e6942ea51ac8399a29 110 Pfam PF13601 Winged helix DNA-binding domain 20 97 4.7E-19 T 12-10-2018 IPR027395 Winged helix DNA-binding domain UA74_09860 c592440883e0c1e6942ea51ac8399a29 110 Gene3D G3DSA:1.10.10.10 8 101 1.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27185 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 1.7E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_27185 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 375 401 1.7E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_27185 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 166 190 1.7E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_27185 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 1.7E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_27185 d5ed37af862a95089b8b20367e933a2b 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 323 342 1.7E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_27185 d5ed37af862a95089b8b20367e933a2b 510 Pfam PF00361 Proton-conducting membrane transporter 131 418 1.9E-61 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_19585 89c52ba5a7eaf5212ed6ca7fc3818439 405 SUPERFAMILY SSF50969 63 399 1.57E-21 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like UA74_19585 89c52ba5a7eaf5212ed6ca7fc3818439 405 Gene3D G3DSA:2.130.10.10 13 272 1.2E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_19585 89c52ba5a7eaf5212ed6ca7fc3818439 405 Gene3D G3DSA:2.130.10.10 275 403 2.4E-7 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_15170 8afe5066d9999ec99203014f035ee867 1033 Pfam PF13700 Domain of unknown function (DUF4158) 5 170 8.3E-50 T 12-10-2018 IPR025296 Domain of unknown function DUF4158 UA74_15170 8afe5066d9999ec99203014f035ee867 1033 Pfam PF01526 Tn3 transposase DDE domain 613 1002 4.8E-133 T 12-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 UA74_19460 ba5d5165af0d2623fa89d9311d65d393 517 Gene3D G3DSA:1.20.1250.20 269 497 7.0E-11 T 12-10-2018 UA74_19460 ba5d5165af0d2623fa89d9311d65d393 517 Pfam PF07690 Major Facilitator Superfamily 24 411 4.5E-42 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_19460 ba5d5165af0d2623fa89d9311d65d393 517 SUPERFAMILY SSF103473 8 496 2.09E-55 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_19460 ba5d5165af0d2623fa89d9311d65d393 517 PRINTS PR01035 Tetracycline resistance protein signature 29 45 1.1E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_19460 ba5d5165af0d2623fa89d9311d65d393 517 PRINTS PR01035 Tetracycline resistance protein signature 331 354 1.1E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_19460 ba5d5165af0d2623fa89d9311d65d393 517 PRINTS PR01035 Tetracycline resistance protein signature 59 78 1.1E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_19460 ba5d5165af0d2623fa89d9311d65d393 517 PRINTS PR01035 Tetracycline resistance protein signature 142 164 1.1E-8 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_19460 ba5d5165af0d2623fa89d9311d65d393 517 Gene3D G3DSA:1.20.1720.10 17 248 9.5E-35 T 12-10-2018 UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 Gene3D G3DSA:3.40.50.10810 461 705 1.1E-62 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 Gene3D G3DSA:3.40.50.300 716 916 4.5E-83 T 12-10-2018 UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 SMART SM00487 488 669 6.9E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 SMART SM00490 820 902 6.2E-27 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 Gene3D G3DSA:1.20.120.850 730 952 4.5E-83 T 12-10-2018 UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 SUPERFAMILY SSF52540 713 957 1.11E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 Pfam PF00176 SNF2 family N-terminal domain 511 774 1.2E-49 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 Pfam PF00271 Helicase conserved C-terminal domain 794 902 5.8E-19 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 SUPERFAMILY SSF52540 474 706 3.19E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15465 00ff550bb5a9167ebf5b4a03a98ac4be 962 Pfam PF12419 SNF2 Helicase protein 318 446 7.7E-31 T 12-10-2018 IPR022138 Helicase SWF/SNF-related UA74_19520 84f44ce0e22e6dd74b4c1ad2819f0952 300 Gene3D G3DSA:1.10.3720.10 26 286 4.7E-55 T 12-10-2018 IPR035906 MetI-like superfamily UA74_19520 84f44ce0e22e6dd74b4c1ad2819f0952 300 SUPERFAMILY SSF161098 28 300 3.66E-66 T 12-10-2018 IPR035906 MetI-like superfamily UA74_19520 84f44ce0e22e6dd74b4c1ad2819f0952 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 292 2.5E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_06055 e27a3799c1909df0a6cd69f126e7bc93 166 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 41 4.4E-8 T 12-10-2018 UA74_06055 e27a3799c1909df0a6cd69f126e7bc93 166 SUPERFAMILY SSF143120 5 44 8.63E-6 T 12-10-2018 IPR036165 YefM-like superfamily UA74_00935 39fc92e57eae012422981eb693f3851d 299 SUPERFAMILY SSF161098 91 277 7.59E-25 T 12-10-2018 IPR035906 MetI-like superfamily UA74_00935 39fc92e57eae012422981eb693f3851d 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 287 2.6E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_00935 39fc92e57eae012422981eb693f3851d 299 Gene3D G3DSA:1.10.3720.10 87 290 2.5E-18 T 12-10-2018 IPR035906 MetI-like superfamily UA74_02255 76ce7070f768ff22760dde519bef94ef 311 Gene3D G3DSA:3.20.20.530 23 309 4.0E-91 T 12-10-2018 UA74_02255 76ce7070f768ff22760dde519bef94ef 311 PIRSF PIRSF000196 4 311 1.0E-106 T 12-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 UA74_02255 76ce7070f768ff22760dde519bef94ef 311 Pfam PF01619 Proline dehydrogenase 49 299 2.4E-33 T 12-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 UA74_02255 76ce7070f768ff22760dde519bef94ef 311 SUPERFAMILY SSF51730 40 306 9.02E-69 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like UA74_04330 af75382c54f7c24e751f07972c69557e 290 Pfam PF12730 ABC-2 family transporter protein 37 197 8.3E-13 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UA74_08525 71ded7d135a7780cfe0b0b9219242e2f 150 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 40 141 7.0E-7 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 UA74_08525 71ded7d135a7780cfe0b0b9219242e2f 150 SUPERFAMILY SSF50118 37 141 7.85E-9 T 12-10-2018 UA74_30265 36ee80a334ec29cc59f273aaeb2c4884 214 SUPERFAMILY SSF55729 33 141 2.93E-10 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_30265 36ee80a334ec29cc59f273aaeb2c4884 214 Gene3D G3DSA:3.40.630.30 24 210 3.2E-8 T 12-10-2018 UA74_09975 93f41a8ba6dd5fd06f372a3ae3f1ef21 127 Gene3D G3DSA:3.10.20.400 3 100 1.5E-38 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 UA74_09975 93f41a8ba6dd5fd06f372a3ae3f1ef21 127 SUPERFAMILY SSF141734 8 114 1.05E-45 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 UA74_09975 93f41a8ba6dd5fd06f372a3ae3f1ef21 127 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 59 108 3.0E-20 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 UA74_09975 93f41a8ba6dd5fd06f372a3ae3f1ef21 127 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 10 113 31.564 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 UA74_09975 93f41a8ba6dd5fd06f372a3ae3f1ef21 127 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 36 108 1.5E-33 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 UA74_14180 a713e3de7ba78ba7400a2767a939c294 642 ProSitePatterns PS00211 ABC transporters family signature. 519 533 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_14180 a713e3de7ba78ba7400a2767a939c294 642 Gene3D G3DSA:3.40.50.300 360 632 2.2E-84 T 12-10-2018 UA74_14180 a713e3de7ba78ba7400a2767a939c294 642 SUPERFAMILY SSF90123 31 351 1.96E-72 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_14180 a713e3de7ba78ba7400a2767a939c294 642 Gene3D G3DSA:1.20.1560.10 14 348 3.8E-77 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_14180 a713e3de7ba78ba7400a2767a939c294 642 SUPERFAMILY SSF52540 354 618 4.6E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14180 a713e3de7ba78ba7400a2767a939c294 642 SMART SM00382 407 593 6.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_14180 a713e3de7ba78ba7400a2767a939c294 642 Pfam PF00005 ABC transporter 398 547 1.6E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_14180 a713e3de7ba78ba7400a2767a939c294 642 Pfam PF00664 ABC transporter transmembrane region 47 316 2.0E-40 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_20710 d2af809dcc337638b48df0022e77230d 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 317 7.4E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_06860 5f53f9e95cb96ac971b2d08e76e930ed 189 SUPERFAMILY SSF46689 8 75 1.9E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_06860 5f53f9e95cb96ac971b2d08e76e930ed 189 Gene3D G3DSA:1.10.357.10 2 189 5.8E-47 T 12-10-2018 UA74_06860 5f53f9e95cb96ac971b2d08e76e930ed 189 SUPERFAMILY SSF48498 85 188 3.89E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_06860 5f53f9e95cb96ac971b2d08e76e930ed 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.8E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06860 5f53f9e95cb96ac971b2d08e76e930ed 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.8E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06860 5f53f9e95cb96ac971b2d08e76e930ed 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 2.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_07040 c7b6cc13166b2e1c086daa6e0d8a973b 91 Hamap MF_01396 ATP synthase subunit c [atpH]. 23 88 14.407 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07040 c7b6cc13166b2e1c086daa6e0d8a973b 91 PRINTS PR00124 ATP synthase C subunit signature 46 61 1.4E-14 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07040 c7b6cc13166b2e1c086daa6e0d8a973b 91 PRINTS PR00124 ATP synthase C subunit signature 63 88 1.4E-14 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07040 c7b6cc13166b2e1c086daa6e0d8a973b 91 PRINTS PR00124 ATP synthase C subunit signature 25 44 1.4E-14 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07040 c7b6cc13166b2e1c086daa6e0d8a973b 91 Pfam PF00137 ATP synthase subunit C 27 86 1.6E-11 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 UA74_07040 c7b6cc13166b2e1c086daa6e0d8a973b 91 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 33 87 5.7E-19 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 UA74_07040 c7b6cc13166b2e1c086daa6e0d8a973b 91 ProSitePatterns PS00605 ATP synthase c subunit signature. 53 74 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_07040 c7b6cc13166b2e1c086daa6e0d8a973b 91 SUPERFAMILY SSF81333 26 87 9.42E-17 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily UA74_07040 c7b6cc13166b2e1c086daa6e0d8a973b 91 Gene3D G3DSA:1.20.20.10 24 87 1.1E-20 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UA74_27900 eda6b454f69213ba194008b8726a7018 406 Pfam PF13411 MerR HTH family regulatory protein 21 85 4.5E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_27900 eda6b454f69213ba194008b8726a7018 406 Gene3D G3DSA:1.10.1660.10 14 89 2.1E-19 T 12-10-2018 UA74_27900 eda6b454f69213ba194008b8726a7018 406 SMART SM00422 20 89 1.6E-4 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_27900 eda6b454f69213ba194008b8726a7018 406 Gene3D G3DSA:3.40.50.280 282 398 6.1E-10 T 12-10-2018 UA74_27900 eda6b454f69213ba194008b8726a7018 406 SUPERFAMILY SSF46955 21 87 1.65E-11 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_29565 7dd82e4b10c56ae420250b98519239be 325 SUPERFAMILY SSF52540 2 222 1.38E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29565 7dd82e4b10c56ae420250b98519239be 325 Pfam PF00005 ABC transporter 18 155 1.7E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_29565 7dd82e4b10c56ae420250b98519239be 325 SMART SM00382 26 204 4.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_29565 7dd82e4b10c56ae420250b98519239be 325 Gene3D G3DSA:3.40.50.300 1 255 2.5E-50 T 12-10-2018 UA74_29695 8bd3ea17089d20df5d3766d42cde7d07 142 ProSitePatterns PS00552 MerR-type HTH domain signature. 20 42 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_29695 8bd3ea17089d20df5d3766d42cde7d07 142 SUPERFAMILY SSF46955 18 103 4.58E-18 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_29695 8bd3ea17089d20df5d3766d42cde7d07 142 Gene3D G3DSA:1.10.1660.10 14 108 2.4E-21 T 12-10-2018 UA74_29695 8bd3ea17089d20df5d3766d42cde7d07 142 Pfam PF13411 MerR HTH family regulatory protein 19 84 1.4E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_29695 8bd3ea17089d20df5d3766d42cde7d07 142 SMART SM00422 17 86 4.1E-23 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_02300 e8dad0b0f4a802922e8422d236cd605a 80 Gene3D G3DSA:3.40.30.10 1 79 1.4E-19 T 12-10-2018 UA74_02300 e8dad0b0f4a802922e8422d236cd605a 80 SUPERFAMILY SSF52833 2 79 9.1E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_02300 e8dad0b0f4a802922e8422d236cd605a 80 Pfam PF05768 Glutaredoxin-like domain (DUF836) 6 78 6.4E-13 T 12-10-2018 IPR008554 Glutaredoxin-like UA74_05405 d4900dd3487559f99b3cb1e821afc833 185 SUPERFAMILY SSF48498 79 178 3.86E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_05405 d4900dd3487559f99b3cb1e821afc833 185 Gene3D G3DSA:1.10.357.10 2 180 7.5E-33 T 12-10-2018 UA74_05405 d4900dd3487559f99b3cb1e821afc833 185 SUPERFAMILY SSF46689 3 67 8.98E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_05405 d4900dd3487559f99b3cb1e821afc833 185 Pfam PF13305 WHG domain 80 160 1.1E-7 T 12-10-2018 IPR025996 WHG domain UA74_05405 d4900dd3487559f99b3cb1e821afc833 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 2.3E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05405 d4900dd3487559f99b3cb1e821afc833 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 7.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05405 d4900dd3487559f99b3cb1e821afc833 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 7.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 Pfam PF00994 Probable molybdopterin binding domain 179 316 2.5E-16 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 SMART SM00852 178 317 5.9E-22 T 12-10-2018 IPR001453 MoaB/Mog domain UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 Gene3D G3DSA:2.40.340.10 328 400 4.2E-21 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 Gene3D G3DSA:2.170.190.11 44 139 3.7E-88 T 12-10-2018 UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 SUPERFAMILY SSF63867 326 403 2.22E-18 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 SUPERFAMILY SSF63882 1 174 1.44E-45 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 SUPERFAMILY SSF53218 175 321 2.75E-30 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 165 8.4E-41 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 Gene3D G3DSA:3.90.105.10 22 172 3.7E-88 T 12-10-2018 UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 Gene3D G3DSA:3.40.980.10 173 316 3.7E-88 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily UA74_03280 deb243806c58c6e58ee68bb872a36cd7 407 Pfam PF03454 MoeA C-terminal region (domain IV) 331 403 4.7E-20 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UA74_27460 e2c6a66870a3f8692d93b0e856a4f1ac 399 Gene3D G3DSA:3.90.20.10 77 201 1.0E-5 T 12-10-2018 UA74_27460 e2c6a66870a3f8692d93b0e856a4f1ac 399 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 2 307 1.0E-5 T 12-10-2018 UA74_27460 e2c6a66870a3f8692d93b0e856a4f1ac 399 SUPERFAMILY SSF58113 177 314 3.79E-7 T 12-10-2018 UA74_27460 e2c6a66870a3f8692d93b0e856a4f1ac 399 Gene3D G3DSA:1.20.120.20 239 353 2.0E-5 T 12-10-2018 UA74_24180 0bc48c26d991fcfecf6f41795efbeb64 310 Gene3D G3DSA:1.10.3720.10 74 309 3.6E-58 T 12-10-2018 IPR035906 MetI-like superfamily UA74_24180 0bc48c26d991fcfecf6f41795efbeb64 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 305 1.5E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_24180 0bc48c26d991fcfecf6f41795efbeb64 310 SUPERFAMILY SSF161098 78 299 4.84E-52 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20640 0ae2aa086b971751030af8cd6a9d8e8e 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 1.3E-13 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UA74_20640 0ae2aa086b971751030af8cd6a9d8e8e 353 Gene3D G3DSA:3.40.50.720 147 322 5.7E-97 T 12-10-2018 UA74_20640 0ae2aa086b971751030af8cd6a9d8e8e 353 Pfam PF16912 Glucose dehydrogenase C-terminus 145 348 6.1E-65 T 12-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 UA74_20640 0ae2aa086b971751030af8cd6a9d8e8e 353 SUPERFAMILY SSF51735 173 283 1.38E-13 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_20640 0ae2aa086b971751030af8cd6a9d8e8e 353 Gene3D G3DSA:3.90.180.10 15 346 5.7E-97 T 12-10-2018 UA74_20640 0ae2aa086b971751030af8cd6a9d8e8e 353 SUPERFAMILY SSF50129 1 183 3.04E-32 T 12-10-2018 IPR011032 GroES-like superfamily UA74_12765 0d5d37592bd803fe75646e33e761d3a7 502 Pfam PF00135 Carboxylesterase family 4 457 6.5E-79 T 12-10-2018 IPR002018 Carboxylesterase, type B UA74_12765 0d5d37592bd803fe75646e33e761d3a7 502 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 171 186 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site UA74_12765 0d5d37592bd803fe75646e33e761d3a7 502 SUPERFAMILY SSF53474 4 462 3.28E-90 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_12765 0d5d37592bd803fe75646e33e761d3a7 502 Gene3D G3DSA:3.40.50.1820 2 477 1.4E-108 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_01080 195973f016854a0275f11ce6fff0fb77 207 Pfam PF00881 Nitroreductase family 114 168 4.8E-7 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_01080 195973f016854a0275f11ce6fff0fb77 207 Pfam PF00881 Nitroreductase family 26 86 6.6E-10 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_01080 195973f016854a0275f11ce6fff0fb77 207 SUPERFAMILY SSF55469 20 204 8.9E-38 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_01080 195973f016854a0275f11ce6fff0fb77 207 Gene3D G3DSA:3.40.109.10 12 206 2.1E-42 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_01370 796b77bf0971b552596664ccd02a366c 436 Gene3D G3DSA:3.40.50.12170 55 435 3.1E-129 T 12-10-2018 UA74_01370 796b77bf0971b552596664ccd02a366c 436 Pfam PF07075 Protein of unknown function (DUF1343) 72 435 3.9E-130 T 12-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 UA74_01370 796b77bf0971b552596664ccd02a366c 436 PIRSF PIRSF016719 20 436 8.0E-136 T 12-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 UA74_01370 796b77bf0971b552596664ccd02a366c 436 Gene3D G3DSA:3.90.1150.140 274 420 3.1E-129 T 12-10-2018 UA74_29980 a131726a574a8fe9f9779ab810d02a19 914 SUPERFAMILY SSF53955 198 398 7.03E-53 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_29980 a131726a574a8fe9f9779ab810d02a19 914 Gene3D G3DSA:1.10.3810.10 214 396 1.6E-50 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_29980 a131726a574a8fe9f9779ab810d02a19 914 Gene3D G3DSA:3.40.710.10 414 797 2.1E-90 T 12-10-2018 UA74_29980 a131726a574a8fe9f9779ab810d02a19 914 SUPERFAMILY SSF56601 363 788 4.43E-62 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_29980 a131726a574a8fe9f9779ab810d02a19 914 Pfam PF00905 Penicillin binding protein transpeptidase domain 472 734 3.1E-25 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UA74_29980 a131726a574a8fe9f9779ab810d02a19 914 Pfam PF00912 Transglycosylase 222 381 2.3E-44 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_07300 76964855d0ecf516b00aed61e6915fd5 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 127 9.662 T 12-10-2018 IPR022907 VapC family GO:0004540 UA74_07300 76964855d0ecf516b00aed61e6915fd5 136 Pfam PF01850 PIN domain 2 116 3.4E-12 T 12-10-2018 IPR002716 PIN domain UA74_07300 76964855d0ecf516b00aed61e6915fd5 136 SUPERFAMILY SSF88723 1 118 6.87E-12 T 12-10-2018 IPR029060 PIN-like domain superfamily UA74_07300 76964855d0ecf516b00aed61e6915fd5 136 Gene3D G3DSA:3.40.50.1010 1 113 6.8E-8 T 12-10-2018 UA74_03715 94d023986684f7f90bc0dedb063d2bd8 321 SUPERFAMILY SSF53955 146 313 2.25E-35 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_03715 94d023986684f7f90bc0dedb063d2bd8 321 Gene3D G3DSA:1.10.530.10 161 319 9.7E-8 T 12-10-2018 UA74_03715 94d023986684f7f90bc0dedb063d2bd8 321 Pfam PF13406 Transglycosylase SLT domain 230 290 1.0E-8 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 UA74_20080 2ebbbc5f58d96c28bec3f36bcfad3a45 157 Gene3D G3DSA:1.10.10.10 2 147 3.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20080 2ebbbc5f58d96c28bec3f36bcfad3a45 157 Pfam PF01047 MarR family 44 96 9.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_20080 2ebbbc5f58d96c28bec3f36bcfad3a45 157 SUPERFAMILY SSF46785 18 149 3.28E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20080 2ebbbc5f58d96c28bec3f36bcfad3a45 157 SMART SM00347 28 133 7.6E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_20080 2ebbbc5f58d96c28bec3f36bcfad3a45 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.0E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_20080 2ebbbc5f58d96c28bec3f36bcfad3a45 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.0E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_20080 2ebbbc5f58d96c28bec3f36bcfad3a45 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.0E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_18820 6c2127de04d2ff89980720593042f275 350 SUPERFAMILY SSF53822 75 346 6.9E-77 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_18820 6c2127de04d2ff89980720593042f275 350 Gene3D G3DSA:3.40.50.2300 175 303 6.8E-72 T 12-10-2018 UA74_18820 6c2127de04d2ff89980720593042f275 350 Gene3D G3DSA:3.40.50.2300 82 335 6.8E-72 T 12-10-2018 UA74_18820 6c2127de04d2ff89980720593042f275 350 Pfam PF13377 Periplasmic binding protein-like domain 182 343 5.1E-42 T 12-10-2018 UA74_18820 6c2127de04d2ff89980720593042f275 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 62 3.1E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_18820 6c2127de04d2ff89980720593042f275 350 SUPERFAMILY SSF47413 17 68 6.33E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_18820 6c2127de04d2ff89980720593042f275 350 Gene3D G3DSA:1.10.260.40 17 73 3.5E-15 T 12-10-2018 UA74_18820 6c2127de04d2ff89980720593042f275 350 SMART SM00354 17 84 3.6E-7 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UA74_16315 c93ac3b4ba79525288f352cde5ccdbce 507 TIGRFAM TIGR02677 TIGR02677: TIGR02677 family protein 12 503 9.1E-66 T 12-10-2018 IPR013493 Conserved hypothetical protein CHP02677 UA74_16315 c93ac3b4ba79525288f352cde5ccdbce 507 Pfam PF09660 Protein of unknown function (DUF2397) 12 497 2.6E-82 T 12-10-2018 IPR013493 Conserved hypothetical protein CHP02677 UA74_21000 0ffb45ba6165d4d5e6aa652bf109e9f0 443 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 304 372 3.4E-12 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_21000 0ffb45ba6165d4d5e6aa652bf109e9f0 443 SUPERFAMILY SSF46785 28 150 2.24E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_21000 0ffb45ba6165d4d5e6aa652bf109e9f0 443 SUPERFAMILY SSF56214 212 296 1.05E-13 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_21000 0ffb45ba6165d4d5e6aa652bf109e9f0 443 SUPERFAMILY SSF56214 304 397 2.49E-16 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_21000 0ffb45ba6165d4d5e6aa652bf109e9f0 443 SMART SM00347 37 137 9.3E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_21000 0ffb45ba6165d4d5e6aa652bf109e9f0 443 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_21000 0ffb45ba6165d4d5e6aa652bf109e9f0 443 Gene3D G3DSA:1.10.10.10 7 155 3.3E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21000 0ffb45ba6165d4d5e6aa652bf109e9f0 443 Gene3D G3DSA:3.90.470.20 204 326 3.8E-22 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_21000 0ffb45ba6165d4d5e6aa652bf109e9f0 443 Pfam PF01047 MarR family 44 101 9.4E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_19145 03001caefd22686f6b020fdb9e52b472 85 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 29 80 9.6E-10 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 UA74_05950 37d63b9d3c5e5574b5291d0ad77cbfc1 337 Gene3D G3DSA:3.40.50.300 3 263 3.9E-64 T 12-10-2018 UA74_05950 37d63b9d3c5e5574b5291d0ad77cbfc1 337 Pfam PF00005 ABC transporter 26 168 7.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_05950 37d63b9d3c5e5574b5291d0ad77cbfc1 337 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_05950 37d63b9d3c5e5574b5291d0ad77cbfc1 337 SUPERFAMILY SSF52540 5 232 2.15E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_05950 37d63b9d3c5e5574b5291d0ad77cbfc1 337 SMART SM00382 34 218 3.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_17475 f6c57ed27df516294c6f3a6b2261a0ff 425 Gene3D G3DSA:3.40.640.10 45 319 7.4E-141 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_17475 f6c57ed27df516294c6f3a6b2261a0ff 425 Gene3D G3DSA:3.90.1150.10 8 420 7.4E-141 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_17475 f6c57ed27df516294c6f3a6b2261a0ff 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 233 270 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_17475 f6c57ed27df516294c6f3a6b2261a0ff 425 SUPERFAMILY SSF53383 9 420 1.6E-107 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_17475 f6c57ed27df516294c6f3a6b2261a0ff 425 PIRSF PIRSF000521 13 421 8.3E-22 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_17475 f6c57ed27df516294c6f3a6b2261a0ff 425 Pfam PF00202 Aminotransferase class-III 10 417 1.5E-82 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_05945 800147a499c82b9199132d9fe46d87fc 313 SUPERFAMILY SSF56112 56 290 8.56E-23 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_05945 800147a499c82b9199132d9fe46d87fc 313 Pfam PF01636 Phosphotransferase enzyme family 67 270 9.1E-18 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_05945 800147a499c82b9199132d9fe46d87fc 313 Gene3D G3DSA:3.90.1200.10 124 307 1.3E-6 T 12-10-2018 UA74_15205 2469feb575ce6b5d5ad6c2a783a5fae7 115 SUPERFAMILY SSF54909 2 111 4.83E-25 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_15205 2469feb575ce6b5d5ad6c2a783a5fae7 115 Pfam PF03795 YCII-related domain 2 110 4.0E-18 T 12-10-2018 IPR005545 YCII-related UA74_15205 2469feb575ce6b5d5ad6c2a783a5fae7 115 Gene3D G3DSA:3.30.70.1060 1 111 6.1E-34 T 12-10-2018 UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 Gene3D G3DSA:3.40.50.970 314 486 1.5E-56 T 12-10-2018 UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 ProSitePatterns PS00802 Transketolase signature 2. 423 439 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 SUPERFAMILY SSF52922 518 642 1.31E-24 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 SMART SM00861 317 482 8.5E-52 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 644 40.809 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 Pfam PF02780 Transketolase, C-terminal domain 517 635 2.4E-24 T 12-10-2018 IPR033248 Transketolase, C-terminal domain UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 SUPERFAMILY SSF52518 3 348 2.75E-67 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 280 2.4E-106 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 SUPERFAMILY SSF52518 296 478 4.98E-51 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 Gene3D G3DSA:3.40.50.920 517 648 2.2E-27 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 481 2.3E-157 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_08505 06adcc0f0960e5175c82b782fe1786f0 662 Pfam PF02779 Transketolase, pyrimidine binding domain 318 478 1.8E-37 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_05225 54cf447e12f87cba3284378421dfed6c 466 SUPERFAMILY SSF54631 222 349 2.02E-24 T 12-10-2018 UA74_05225 54cf447e12f87cba3284378421dfed6c 466 Pfam PF00571 CBS domain 284 338 0.0046 T 12-10-2018 IPR000644 CBS domain UA74_05225 54cf447e12f87cba3284378421dfed6c 466 Pfam PF00571 CBS domain 228 276 2.0E-5 T 12-10-2018 IPR000644 CBS domain UA74_05225 54cf447e12f87cba3284378421dfed6c 466 SUPERFAMILY SSF56176 354 450 7.91E-13 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UA74_05225 54cf447e12f87cba3284378421dfed6c 466 Gene3D G3DSA:3.10.580.10 205 348 9.6E-34 T 12-10-2018 UA74_05225 54cf447e12f87cba3284378421dfed6c 466 Gene3D G3DSA:3.30.465.10 351 447 1.8E-16 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UA74_05225 54cf447e12f87cba3284378421dfed6c 466 Pfam PF01595 Domain of unknown function DUF21 13 206 3.4E-35 T 12-10-2018 IPR002550 CNNM, transmembrane domain UA74_05225 54cf447e12f87cba3284378421dfed6c 466 Pfam PF03471 Transporter associated domain 357 447 3.6E-12 T 12-10-2018 IPR005170 Transporter-associated domain UA74_05225 54cf447e12f87cba3284378421dfed6c 466 SMART SM01091 354 448 4.7E-10 T 12-10-2018 IPR005170 Transporter-associated domain UA74_16035 0ea96d0ba933736c4dd0a1a997dda7b2 421 SUPERFAMILY SSF56801 108 338 4.71E-20 T 12-10-2018 UA74_16035 0ea96d0ba933736c4dd0a1a997dda7b2 421 Gene3D G3DSA:3.40.50.12780 37 337 5.5E-18 T 12-10-2018 UA74_16035 0ea96d0ba933736c4dd0a1a997dda7b2 421 Pfam PF00501 AMP-binding enzyme 131 336 1.1E-11 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_23585 1597c89eb62762d0778bfa68d51369ad 274 SUPERFAMILY SSF51658 7 263 7.07E-55 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_23585 1597c89eb62762d0778bfa68d51369ad 274 Gene3D G3DSA:3.20.20.150 2 271 9.8E-67 T 12-10-2018 UA74_23585 1597c89eb62762d0778bfa68d51369ad 274 Pfam PF01261 Xylose isomerase-like TIM barrel 43 220 1.3E-30 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_22510 aade88f26d0da8137f495487d3da2894 152 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 31 99 1.1E-12 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_22510 aade88f26d0da8137f495487d3da2894 152 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 21 146 1.6E-24 T 12-10-2018 IPR019920 F420-binding domain, putative UA74_22510 aade88f26d0da8137f495487d3da2894 152 Gene3D G3DSA:2.30.110.10 12 146 1.5E-26 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_22510 aade88f26d0da8137f495487d3da2894 152 SUPERFAMILY SSF50475 14 148 1.18E-22 T 12-10-2018 UA74_09025 b57f9f36ea86759d489e905823c30bb9 295 Pfam PF08445 FR47-like protein 223 286 8.0E-13 T 12-10-2018 IPR013653 FR47-like GO:0016747 UA74_09025 b57f9f36ea86759d489e905823c30bb9 295 Pfam PF13312 Domain of unknown function (DUF4081) 65 167 4.7E-42 T 12-10-2018 IPR025289 Domain of unknown function DUF4081 UA74_09025 b57f9f36ea86759d489e905823c30bb9 295 SUPERFAMILY SSF55729 90 290 1.95E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_09025 b57f9f36ea86759d489e905823c30bb9 295 Gene3D G3DSA:3.40.630.30 84 294 3.1E-20 T 12-10-2018 UA74_09025 b57f9f36ea86759d489e905823c30bb9 295 PIRSF PIRSF021603 17 295 3.3E-113 T 12-10-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like UA74_07225 ecec5c9f161b903ab1377ea01a41af98 99 Gene3D G3DSA:3.30.70.930 1 98 1.3E-27 T 12-10-2018 IPR029756 MTH1187/YkoF-like UA74_07225 ecec5c9f161b903ab1377ea01a41af98 99 SUPERFAMILY SSF89957 1 97 7.06E-29 T 12-10-2018 IPR029756 MTH1187/YkoF-like UA74_07225 ecec5c9f161b903ab1377ea01a41af98 99 Pfam PF01910 Thiamine-binding protein 4 93 3.9E-31 T 12-10-2018 IPR002767 Thiamine-binding protein UA74_07225 ecec5c9f161b903ab1377ea01a41af98 99 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 95 5.5E-18 T 12-10-2018 IPR002767 Thiamine-binding protein UA74_10285 009c7be7a56d08fd4eafcf3778671285 95 SUPERFAMILY SSF46785 2 88 1.93E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_10285 009c7be7a56d08fd4eafcf3778671285 95 Pfam PF01638 HxlR-like helix-turn-helix 1 79 2.0E-18 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_10285 009c7be7a56d08fd4eafcf3778671285 95 Gene3D G3DSA:1.10.10.10 1 91 4.4E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12390 8eee32e6464a1e085c0a058fb57cd3a2 277 Pfam PF01494 FAD binding domain 6 275 1.4E-43 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_12390 8eee32e6464a1e085c0a058fb57cd3a2 277 Gene3D G3DSA:3.50.50.60 7 189 3.9E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_12390 8eee32e6464a1e085c0a058fb57cd3a2 277 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.2E-11 T 12-10-2018 UA74_12390 8eee32e6464a1e085c0a058fb57cd3a2 277 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 1.2E-11 T 12-10-2018 UA74_12390 8eee32e6464a1e085c0a058fb57cd3a2 277 Gene3D G3DSA:3.30.9.50 74 274 3.9E-54 T 12-10-2018 UA74_12390 8eee32e6464a1e085c0a058fb57cd3a2 277 SUPERFAMILY SSF51905 7 190 5.51E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 SUPERFAMILY SSF48264 21 390 2.75E-83 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 Gene3D G3DSA:1.10.630.10 13 396 3.0E-119 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 Pfam PF00067 Cytochrome P450 44 367 4.1E-23 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 189 211 7.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 82 93 7.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 145 160 7.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 128 144 7.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 336 345 7.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 315 330 7.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 270 281 7.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 287 314 7.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_10850 1692231d7419c9c9c5a35053a64ca88d 397 PRINTS PR00359 B-class P450 signature 345 356 7.7E-53 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_09655 d4aad558c09d478ab267698ffea2f100 311 Pfam PF03799 Cell division protein FtsQ 202 296 1.3E-5 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB UA74_09655 d4aad558c09d478ab267698ffea2f100 311 Pfam PF08478 POTRA domain, FtsQ-type 121 188 2.5E-14 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 Gene3D G3DSA:3.50.50.60 35 360 3.5E-88 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 389 494 2.3E-20 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 SUPERFAMILY SSF55424 385 499 4.12E-26 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 35 346 7.8E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 178 2.3E-51 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 68 83 2.3E-51 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 304 2.3E-51 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 341 2.3E-51 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 58 2.3E-51 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 205 230 2.3E-51 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 450 465 2.3E-51 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 472 492 2.3E-51 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 385 406 2.3E-51 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 Gene3D G3DSA:3.50.50.60 185 303 3.5E-88 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 Gene3D G3DSA:3.30.390.30 387 502 1.1E-24 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 SUPERFAMILY SSF51905 30 364 4.34E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PIRSF PIRSF000350 16 498 5.1E-77 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 37 56 1.5E-20 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 205 223 1.5E-20 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.5E-20 T 12-10-2018 UA74_25455 4c694d14ca0f6b6516ca80affbb52062 503 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 305 1.5E-20 T 12-10-2018 UA74_19345 6621d73195a2603ac6b06b84cad4b527 827 SMART SM00530 8 64 8.1E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_19345 6621d73195a2603ac6b06b84cad4b527 827 SUPERFAMILY SSF52540 191 385 8.62E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19345 6621d73195a2603ac6b06b84cad4b527 827 SUPERFAMILY SSF47413 3 60 3.38E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_19345 6621d73195a2603ac6b06b84cad4b527 827 Pfam PF13560 Helix-turn-helix domain 4 66 1.3E-16 T 12-10-2018 UA74_19345 6621d73195a2603ac6b06b84cad4b527 827 Pfam PF05729 NACHT domain 226 379 2.5E-7 T 12-10-2018 IPR007111 NACHT nucleoside triphosphatase UA74_19345 6621d73195a2603ac6b06b84cad4b527 827 Gene3D G3DSA:1.10.260.40 2 76 2.4E-15 T 12-10-2018 UA74_27605 686907e16ec5a76c61bb5df1b4bc3a7e 431 Pfam PF07690 Major Facilitator Superfamily 31 238 3.4E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_27605 686907e16ec5a76c61bb5df1b4bc3a7e 431 Gene3D G3DSA:1.20.1250.20 15 416 1.6E-23 T 12-10-2018 UA74_27605 686907e16ec5a76c61bb5df1b4bc3a7e 431 SUPERFAMILY SSF103473 16 421 6.54E-30 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_20235 abf659c57a73c32d1b8ddb6555a54f56 267 Pfam PF12833 Helix-turn-helix domain 179 255 5.7E-14 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_20235 abf659c57a73c32d1b8ddb6555a54f56 267 Gene3D G3DSA:1.10.10.60 157 258 1.4E-16 T 12-10-2018 UA74_20235 abf659c57a73c32d1b8ddb6555a54f56 267 SMART SM00342 172 255 8.6E-10 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_28615 7492b4cb17ebe128efb05a766af9079b 242 Gene3D G3DSA:3.40.50.300 16 239 4.3E-59 T 12-10-2018 UA74_28615 7492b4cb17ebe128efb05a766af9079b 242 SMART SM00382 41 230 4.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_28615 7492b4cb17ebe128efb05a766af9079b 242 SUPERFAMILY SSF52540 20 231 7.57E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28615 7492b4cb17ebe128efb05a766af9079b 242 Pfam PF00005 ABC transporter 35 180 9.9E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_02735 14cf1044fea3ecb06ba3fb5a26891077 549 Pfam PF00561 alpha/beta hydrolase fold 111 268 4.6E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_02735 14cf1044fea3ecb06ba3fb5a26891077 549 SUPERFAMILY SSF53474 110 516 7.21E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_02735 14cf1044fea3ecb06ba3fb5a26891077 549 Pfam PF08386 TAP-like protein 444 543 8.5E-24 T 12-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal UA74_09670 16c2eed66ebaf2748a8fec07fbd6418a 293 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 11 287 4.7E-85 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B UA74_09670 16c2eed66ebaf2748a8fec07fbd6418a 293 SUPERFAMILY SSF50891 180 288 1.18E-13 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily UA74_09670 16c2eed66ebaf2748a8fec07fbd6418a 293 Gene3D G3DSA:2.40.100.10 177 291 1.1E-40 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily UA74_09670 16c2eed66ebaf2748a8fec07fbd6418a 293 SMART SM00797 30 290 8.1E-105 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B UA74_09670 16c2eed66ebaf2748a8fec07fbd6418a 293 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 31 287 1.5E-84 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B UA74_20935 ef59931ab21969bd2f3efdd655b3dac3 277 Gene3D G3DSA:3.30.470.20 168 273 1.4E-13 T 12-10-2018 UA74_20935 ef59931ab21969bd2f3efdd655b3dac3 277 SUPERFAMILY SSF56059 82 270 1.03E-14 T 12-10-2018 UA74_28805 c4d2350d7662ec818cd1c6bee49adb90 319 Gene3D G3DSA:3.90.550.10 10 247 1.0E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_28805 c4d2350d7662ec818cd1c6bee49adb90 319 Pfam PF00535 Glycosyl transferase family 2 23 154 3.5E-25 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_28805 c4d2350d7662ec818cd1c6bee49adb90 319 SUPERFAMILY SSF53448 19 234 1.83E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_14300 10f7b0e07f450e0332facf15b5d8f242 458 Gene3D G3DSA:3.90.1150.160 358 458 2.7E-28 T 12-10-2018 UA74_14300 10f7b0e07f450e0332facf15b5d8f242 458 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 54 375 8.3E-69 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 UA74_14300 10f7b0e07f450e0332facf15b5d8f242 458 Gene3D G3DSA:3.40.640.10 73 356 5.9E-78 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_14300 10f7b0e07f450e0332facf15b5d8f242 458 SUPERFAMILY SSF53383 31 442 8.05E-122 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_14300 10f7b0e07f450e0332facf15b5d8f242 458 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 33 442 1.1E-180 T 12-10-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 Pfam PF02274 Amidinotransferase 27 405 4.6E-97 T 12-10-2018 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 Gene3D G3DSA:3.75.10.10 15 405 5.0E-141 T 12-10-2018 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 PRINTS PR01466 Bacterial arginine deiminase signature 159 177 1.2E-47 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 PRINTS PR01466 Bacterial arginine deiminase signature 344 361 1.2E-47 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 PRINTS PR01466 Bacterial arginine deiminase signature 387 405 1.2E-47 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 PRINTS PR01466 Bacterial arginine deiminase signature 11 31 1.2E-47 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 PRINTS PR01466 Bacterial arginine deiminase signature 187 202 1.2E-47 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 PRINTS PR01466 Bacterial arginine deiminase signature 364 378 1.2E-47 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 PIRSF PIRSF006356 9 408 1.1E-134 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 SUPERFAMILY SSF55909 12 408 3.14E-114 T 12-10-2018 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 Gene3D G3DSA:1.10.3930.10 77 158 5.0E-141 T 12-10-2018 UA74_00505 e930099ffb9be2e5dd150ded17a7899f 409 Hamap MF_00242 Arginine deiminase [arcA]. 10 408 41.941 T 12-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 31 264 6.9E-57 T 12-10-2018 UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 SUPERFAMILY SSF51735 22 267 1.43E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 192 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 161 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 Gene3D G3DSA:3.40.50.720 13 270 1.1E-74 T 12-10-2018 UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 6.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 6.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 6.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 6.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 192 6.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 163 6.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_18255 4e5a13ef2ca89257e07a7ac7e0494e1d 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 160 188 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 191 218 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 SUPERFAMILY SSF52172 32 152 3.7E-25 T 12-10-2018 IPR011006 CheY-like superfamily UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 Pfam PF00072 Response regulator receiver domain 33 136 3.7E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 Gene3D G3DSA:3.40.50.12740 32 237 3.7E-50 T 12-10-2018 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 231 1.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 SMART SM00421 174 231 6.6E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 SMART SM00448 31 143 2.6E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 1.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 1.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 1.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_23730 0caf06f635f5b197d6bf56eaa432603d 238 SUPERFAMILY SSF46894 171 237 2.45E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_23820 4d1bf10edaec579a6b0e03c462f43d67 575 Pfam PF04616 Glycosyl hydrolases family 43 36 309 3.3E-68 T 12-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UA74_23820 4d1bf10edaec579a6b0e03c462f43d67 575 Gene3D G3DSA:2.115.10.20 30 320 4.4E-72 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_23820 4d1bf10edaec579a6b0e03c462f43d67 575 Gene3D G3DSA:2.60.120.200 348 545 2.3E-35 T 12-10-2018 UA74_23820 4d1bf10edaec579a6b0e03c462f43d67 575 SUPERFAMILY SSF75005 36 314 1.45E-75 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_23820 4d1bf10edaec579a6b0e03c462f43d67 575 SUPERFAMILY SSF49899 352 542 9.1E-25 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UA74_06385 8e21f7a76a596a63a2194d319396f8fe 437 Pfam PF00534 Glycosyl transferases group 1 213 374 1.8E-39 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_06385 8e21f7a76a596a63a2194d319396f8fe 437 SUPERFAMILY SSF53756 1 394 4.19E-95 T 12-10-2018 UA74_06385 8e21f7a76a596a63a2194d319396f8fe 437 Gene3D G3DSA:3.40.50.2000 5 393 2.4E-100 T 12-10-2018 UA74_06385 8e21f7a76a596a63a2194d319396f8fe 437 Gene3D G3DSA:3.40.50.2000 195 376 2.4E-100 T 12-10-2018 UA74_06385 8e21f7a76a596a63a2194d319396f8fe 437 Pfam PF13439 Glycosyltransferase Family 4 15 197 1.1E-31 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 SUPERFAMILY SSF52922 607 736 1.14E-27 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 Gene3D G3DSA:3.40.50.920 609 736 3.0E-24 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 Pfam PF02779 Transketolase, pyrimidine binding domain 402 574 1.4E-25 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 Pfam PF02780 Transketolase, C-terminal domain 610 716 4.2E-21 T 12-10-2018 IPR033248 Transketolase, C-terminal domain UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 SMART SM00861 401 582 1.1E-41 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 SUPERFAMILY SSF52518 34 357 8.42E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 SUPERFAMILY SSF52518 400 589 5.89E-46 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 Pfam PF00676 Dehydrogenase E1 component 71 354 2.3E-26 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 Gene3D G3DSA:3.40.50.970 24 366 1.1E-58 T 12-10-2018 UA74_21380 c370bcd4859585f9e3a7bac7d386b177 737 Gene3D G3DSA:3.40.50.970 399 595 1.8E-61 T 12-10-2018 UA74_19870 a4f10d3ea6d6aa60a1a3df0202826bcb 250 Pfam PF08021 Siderophore-interacting FAD-binding domain 22 122 9.9E-10 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting UA74_19870 a4f10d3ea6d6aa60a1a3df0202826bcb 250 Gene3D G3DSA:3.40.50.80 123 249 3.6E-19 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UA74_19870 a4f10d3ea6d6aa60a1a3df0202826bcb 250 Gene3D G3DSA:2.40.30.10 15 121 1.0E-13 T 12-10-2018 UA74_19870 a4f10d3ea6d6aa60a1a3df0202826bcb 250 Pfam PF04954 Siderophore-interacting protein 130 245 1.7E-23 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain UA74_19870 a4f10d3ea6d6aa60a1a3df0202826bcb 250 SUPERFAMILY SSF63380 14 126 5.38E-16 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UA74_02500 7ef8a188a1a06e1c9bc5962e61746796 388 Gene3D G3DSA:3.60.120.10 6 386 2.9E-91 T 12-10-2018 IPR005801 ADC synthase GO:0009058 UA74_02500 7ef8a188a1a06e1c9bc5962e61746796 388 SUPERFAMILY SSF56322 8 386 3.01E-81 T 12-10-2018 IPR005801 ADC synthase GO:0009058 UA74_02500 7ef8a188a1a06e1c9bc5962e61746796 388 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 112 385 9.8E-74 T 12-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 UA74_02500 7ef8a188a1a06e1c9bc5962e61746796 388 Pfam PF00425 chorismate binding enzyme 129 377 1.3E-67 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal UA74_29770 426c00599bb61d576ec7262feaacd4f4 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 89 200 5.1E-17 T 12-10-2018 UA74_29770 426c00599bb61d576ec7262feaacd4f4 227 SUPERFAMILY SSF56784 15 221 1.38E-27 T 12-10-2018 IPR036412 HAD-like superfamily UA74_29770 426c00599bb61d576ec7262feaacd4f4 227 Gene3D G3DSA:1.10.150.240 84 96 2.3E-25 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_29770 426c00599bb61d576ec7262feaacd4f4 227 Gene3D G3DSA:3.40.50.1000 97 217 2.3E-25 T 12-10-2018 IPR023214 HAD superfamily UA74_29770 426c00599bb61d576ec7262feaacd4f4 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 193 1.2E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_11620 c8e5a9db8f5caf2ed5e12286d0514a11 164 SUPERFAMILY SSF50891 5 147 9.86E-9 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily UA74_11620 c8e5a9db8f5caf2ed5e12286d0514a11 164 Pfam PF12903 Protein of unknown function (DUF3830) 7 161 1.1E-60 T 12-10-2018 IPR024532 Protein of unknown function DUF3830 UA74_11620 c8e5a9db8f5caf2ed5e12286d0514a11 164 Gene3D G3DSA:2.40.100.20 2 164 2.3E-55 T 12-10-2018 UA74_18535 cb2e00db8a8500e7307022b7bfe7e56d 226 SUPERFAMILY SSF55729 35 222 3.37E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_18535 cb2e00db8a8500e7307022b7bfe7e56d 226 Pfam PF13673 Acetyltransferase (GNAT) domain 136 220 1.2E-9 T 12-10-2018 IPR000182 GNAT domain UA74_18535 cb2e00db8a8500e7307022b7bfe7e56d 226 Gene3D G3DSA:3.40.630.30 33 226 2.4E-40 T 12-10-2018 UA74_25540 a16824af732ca39f0671b5c950c46db6 112 Gene3D G3DSA:3.30.70.100 22 109 1.6E-22 T 12-10-2018 UA74_25540 a16824af732ca39f0671b5c950c46db6 112 Pfam PF00708 Acylphosphatase 28 101 5.9E-21 T 12-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UA74_25540 a16824af732ca39f0671b5c950c46db6 112 ProSitePatterns PS00150 Acylphosphatase signature 1. 31 41 - T 12-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UA74_25540 a16824af732ca39f0671b5c950c46db6 112 SUPERFAMILY SSF54975 24 109 6.98E-23 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 349 358 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 Gene3D G3DSA:1.10.630.10 17 408 1.7E-103 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 298 325 5.9E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 197 219 5.9E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 147 163 5.9E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 356 367 5.9E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 326 341 5.9E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 347 356 5.9E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 100 111 5.9E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 281 292 5.9E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00359 B-class P450 signature 164 179 5.9E-46 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 Pfam PF00067 Cytochrome P450 188 377 4.9E-22 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00385 P450 superfamily signature 246 263 2.3E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00385 P450 superfamily signature 347 356 2.3E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00385 P450 superfamily signature 281 292 2.3E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 PRINTS PR00385 P450 superfamily signature 356 367 2.3E-7 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17565 61865cddbd60b2b89ec88855a32ac692 408 SUPERFAMILY SSF48264 21 408 3.93E-85 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_04325 585dae1fc9558da6ccaf1ee36cf5907a 492 SUPERFAMILY SSF51905 89 461 1.24E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_04325 585dae1fc9558da6ccaf1ee36cf5907a 492 Gene3D G3DSA:3.30.9.50 127 358 2.2E-57 T 12-10-2018 UA74_04325 585dae1fc9558da6ccaf1ee36cf5907a 492 Gene3D G3DSA:3.50.50.60 94 429 2.2E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_04325 585dae1fc9558da6ccaf1ee36cf5907a 492 Pfam PF01494 FAD binding domain 90 423 4.2E-17 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_04325 585dae1fc9558da6ccaf1ee36cf5907a 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 234 249 6.4E-10 T 12-10-2018 UA74_04325 585dae1fc9558da6ccaf1ee36cf5907a 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 91 113 6.4E-10 T 12-10-2018 UA74_04325 585dae1fc9558da6ccaf1ee36cf5907a 492 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 368 383 6.4E-10 T 12-10-2018 UA74_14125 9c511a611a2fbec4ee5d3ccd21254c83 361 Pfam PF13419 Haloacid dehalogenase-like hydrolase 146 326 1.4E-23 T 12-10-2018 UA74_14125 9c511a611a2fbec4ee5d3ccd21254c83 361 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 224 326 8.4E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_14125 9c511a611a2fbec4ee5d3ccd21254c83 361 SUPERFAMILY SSF56784 143 329 2.17E-44 T 12-10-2018 IPR036412 HAD-like superfamily UA74_14125 9c511a611a2fbec4ee5d3ccd21254c83 361 Gene3D G3DSA:3.40.50.1000 144 340 4.5E-45 T 12-10-2018 IPR023214 HAD superfamily UA74_14125 9c511a611a2fbec4ee5d3ccd21254c83 361 Gene3D G3DSA:1.10.150.240 157 226 4.5E-45 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_30285 f7ff8cfb6ee6fc1b5b7e638973169174 299 SUPERFAMILY SSF52540 39 289 7.75E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_30285 f7ff8cfb6ee6fc1b5b7e638973169174 299 Gene3D G3DSA:3.40.50.300 34 295 1.5E-76 T 12-10-2018 UA74_30285 f7ff8cfb6ee6fc1b5b7e638973169174 299 Pfam PF13614 AAA domain 39 216 3.2E-57 T 12-10-2018 IPR025669 AAA domain UA74_25795 d021258b47b13c738ee44d7b4f92ff8e 228 SUPERFAMILY SSF50475 15 200 8.45E-52 T 12-10-2018 UA74_25795 d021258b47b13c738ee44d7b4f92ff8e 228 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 35 177 1.2E-42 T 12-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related UA74_25795 d021258b47b13c738ee44d7b4f92ff8e 228 Gene3D G3DSA:2.30.110.10 16 228 1.2E-66 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_27500 0b1ff9627c3fe06c41b4d2b7929fc3e3 141 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 14 123 1.6E-14 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27500 0b1ff9627c3fe06c41b4d2b7929fc3e3 141 Gene3D G3DSA:1.20.1300.10 21 135 1.3E-23 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_27500 0b1ff9627c3fe06c41b4d2b7929fc3e3 141 SUPERFAMILY SSF81343 9 137 5.45E-32 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_00865 671eb3ed2a8a637bebebc07dcda6b186 71 Pfam PF05532 CsbD-like 5 56 2.7E-14 T 12-10-2018 IPR008462 CsbD-like domain UA74_00865 671eb3ed2a8a637bebebc07dcda6b186 71 Gene3D G3DSA:1.10.1470.10 4 66 4.0E-6 T 12-10-2018 IPR036629 YjbJ superfamily UA74_00865 671eb3ed2a8a637bebebc07dcda6b186 71 SUPERFAMILY SSF69047 5 66 7.45E-9 T 12-10-2018 IPR036629 YjbJ superfamily UA74_22690 14b1e74e65c86ca088d271889ce7ab7e 335 Gene3D G3DSA:3.20.20.120 67 297 3.6E-126 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_22690 14b1e74e65c86ca088d271889ce7ab7e 335 SMART SM00922 83 183 5.3E-21 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UA74_22690 14b1e74e65c86ca088d271889ce7ab7e 335 SUPERFAMILY SSF51604 72 294 2.36E-49 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UA74_22690 14b1e74e65c86ca088d271889ce7ab7e 335 Pfam PF13378 Enolase C-terminal domain-like 88 293 1.1E-34 T 12-10-2018 IPR029065 Enolase C-terminal domain-like UA74_22690 14b1e74e65c86ca088d271889ce7ab7e 335 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 5 315 22.477 T 12-10-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 UA74_22690 14b1e74e65c86ca088d271889ce7ab7e 335 Gene3D G3DSA:3.30.390.10 14 319 3.6E-126 T 12-10-2018 IPR029017 Enolase-like, N-terminal UA74_20660 a52f2e03c6994fcc290bc3a58c0c0af4 155 PRINTS PR00502 NUDIX hydrolase family signature 53 68 2.1E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_20660 a52f2e03c6994fcc290bc3a58c0c0af4 155 PRINTS PR00502 NUDIX hydrolase family signature 38 52 2.1E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_20660 a52f2e03c6994fcc290bc3a58c0c0af4 155 Pfam PF00293 NUDIX domain 10 126 2.3E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_20660 a52f2e03c6994fcc290bc3a58c0c0af4 155 Gene3D G3DSA:3.90.79.10 2 141 1.0E-19 T 12-10-2018 UA74_20660 a52f2e03c6994fcc290bc3a58c0c0af4 155 SUPERFAMILY SSF55811 7 135 2.98E-21 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_14255 4e92b6d9323cdf7b62af17f53c9166c2 84 Pfam PF13683 Integrase core domain 27 72 3.8E-10 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 UA74_14255 4e92b6d9323cdf7b62af17f53c9166c2 84 SUPERFAMILY SSF53098 27 79 3.98E-5 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_09230 87b18b8fe49ea604fb19c6836f64639a 224 Gene3D G3DSA:3.30.300.70 24 94 1.0E-7 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily UA74_09230 87b18b8fe49ea604fb19c6836f64639a 224 Pfam PF17384 RimP C-terminal SH3 domain 120 181 1.1E-7 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal UA74_09230 87b18b8fe49ea604fb19c6836f64639a 224 SUPERFAMILY SSF75420 26 117 1.7E-14 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily UA74_09230 87b18b8fe49ea604fb19c6836f64639a 224 Pfam PF02576 RimP N-terminal domain 32 117 4.0E-12 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal UA74_09230 87b18b8fe49ea604fb19c6836f64639a 224 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 26 181 20.224 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 UA74_09230 87b18b8fe49ea604fb19c6836f64639a 224 SUPERFAMILY SSF74942 118 181 9.68E-5 T 12-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 SUPERFAMILY SSF48264 18 444 2.36E-81 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00385 P450 superfamily signature 267 284 1.2E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00385 P450 superfamily signature 382 391 1.2E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00385 P450 superfamily signature 310 321 1.2E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00385 P450 superfamily signature 391 402 1.2E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 Gene3D G3DSA:1.10.630.10 10 442 2.0E-81 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 45 64 1.7E-24 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 391 414 1.7E-24 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 309 327 1.7E-24 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 349 373 1.7E-24 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 381 391 1.7E-24 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 256 273 1.7E-24 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 PRINTS PR00463 E-class P450 group I signature 276 302 1.7E-24 T 12-10-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 384 393 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_12715 e75d78344f054db3a974c5bb1d8afa2d 444 Pfam PF00067 Cytochrome P450 19 428 1.2E-51 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_14275 1143779ca33ba022c2cf242e244540da 103 SUPERFAMILY SSF51679 2 96 7.57E-6 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_14275 1143779ca33ba022c2cf242e244540da 103 Gene3D G3DSA:3.20.20.30 1 98 5.4E-8 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_23450 9fb830bc5a55cdec93b21f7e067681b0 397 SMART SM00331 166 380 3.2E-14 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_23450 9fb830bc5a55cdec93b21f7e067681b0 397 Gene3D G3DSA:3.60.40.10 165 388 4.4E-38 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_23450 9fb830bc5a55cdec93b21f7e067681b0 397 SUPERFAMILY SSF81606 183 377 7.85E-7 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_23450 9fb830bc5a55cdec93b21f7e067681b0 397 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 194 380 2.0E-29 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_29800 64262c0718bf7266f7ccb36cad8b6ea9 379 Pfam PF04230 Polysaccharide pyruvyl transferase 20 321 3.5E-17 T 12-10-2018 IPR007345 Polysaccharide pyruvyl transferase UA74_04880 02730b5442fa9702a34c4fcd403dea79 220 Gene3D G3DSA:3.30.2010.10 114 197 2.9E-11 T 12-10-2018 UA74_04880 02730b5442fa9702a34c4fcd403dea79 220 Pfam PF01863 Protein of unknown function DUF45 104 188 1.5E-20 T 12-10-2018 IPR002725 Protein of unknown function DUF45 UA74_27755 2aada8b827b2a30cceaa85d5665f3803 829 Pfam PF00580 UvrD/REP helicase N-terminal domain 30 313 3.4E-74 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UA74_27755 2aada8b827b2a30cceaa85d5665f3803 829 Pfam PF13361 UvrD-like helicase C-terminal domain 319 690 4.1E-64 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_27755 2aada8b827b2a30cceaa85d5665f3803 829 Gene3D G3DSA:3.40.50.300 30 316 1.5E-93 T 12-10-2018 UA74_27755 2aada8b827b2a30cceaa85d5665f3803 829 SUPERFAMILY SSF52540 26 718 1.3E-168 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_27755 2aada8b827b2a30cceaa85d5665f3803 829 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 26 821 9.1E-281 T 12-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 UA74_27755 2aada8b827b2a30cceaa85d5665f3803 829 Gene3D G3DSA:1.10.10.160 145 219 1.5E-93 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily UA74_00245 16980ee6014c79453b7b2a31b059998b 598 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 74 527 2.7E-160 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 UA74_00245 16980ee6014c79453b7b2a31b059998b 598 ProSitePatterns PS01303 BCCT family of transporters signature. 343 352 - T 12-10-2018 IPR018093 BCCT transporter, conserved site UA74_00245 16980ee6014c79453b7b2a31b059998b 598 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 36 526 1.8E-177 T 12-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 UA74_27905 d31b9681eff58d8d8d25c9df7e9691f0 100 Pfam PF02467 Transcription factor WhiB 17 85 2.2E-24 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain UA74_27905 d31b9681eff58d8d8d25c9df7e9691f0 100 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 18.752 T 12-10-2018 IPR003482 Transcription factor WhiB UA74_18770 b3f1e0824870b80e23c88c22f4e0ff1b 296 SUPERFAMILY SSF161098 59 285 1.44E-57 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18770 b3f1e0824870b80e23c88c22f4e0ff1b 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 290 2.6E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_18770 b3f1e0824870b80e23c88c22f4e0ff1b 296 SUPERFAMILY SSF160964 10 43 2.35E-7 T 12-10-2018 UA74_18770 b3f1e0824870b80e23c88c22f4e0ff1b 296 Gene3D G3DSA:1.10.3720.10 53 296 2.6E-65 T 12-10-2018 IPR035906 MetI-like superfamily UA74_14520 ade2b4522623cbbceddf76c0f6ed146b 206 Gene3D G3DSA:3.40.50.1820 3 205 1.6E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_14520 ade2b4522623cbbceddf76c0f6ed146b 206 Pfam PF02230 Phospholipase/Carboxylesterase 14 203 4.6E-13 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 UA74_14520 ade2b4522623cbbceddf76c0f6ed146b 206 SUPERFAMILY SSF53474 10 204 1.28E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07640 9c0994ff65116826ac754ce13ba77931 360 SUPERFAMILY SSF53850 142 263 6.64E-5 T 12-10-2018 UA74_07640 9c0994ff65116826ac754ce13ba77931 360 SUPERFAMILY SSF46785 29 134 1.73E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_07640 9c0994ff65116826ac754ce13ba77931 360 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 31 95 5.9E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_07640 9c0994ff65116826ac754ce13ba77931 360 Gene3D G3DSA:1.10.10.10 28 122 6.3E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21515 ae6a946e91ea8957eaa40c582a71eee9 162 Pfam PF08044 Domain of unknown function (DUF1707) 11 62 2.2E-17 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 UA74_21515 ae6a946e91ea8957eaa40c582a71eee9 162 Pfam PF05154 TM2 domain 95 145 8.8E-11 T 12-10-2018 IPR007829 TM2 domain UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 Gene3D G3DSA:3.90.380.10 159 226 2.6E-16 T 12-10-2018 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 Gene3D G3DSA:3.90.380.10 227 381 1.6E-30 T 12-10-2018 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 SUPERFAMILY SSF50022 12 149 4.58E-43 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 Gene3D G3DSA:2.102.10.10 35 158 1.6E-33 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 51 66 4.4E-21 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 179 201 4.4E-21 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 4.4E-21 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 21 46 4.4E-21 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 72 92 4.4E-21 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 SUPERFAMILY SSF55961 173 372 7.61E-42 T 12-10-2018 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 Pfam PF00355 Rieske [2Fe-2S] domain 37 121 4.1E-16 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_06600 4ec6dc2a2240fb1365d5a28513fcbe7e 383 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 181 371 4.8E-44 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 UA74_03350 3a8c46de47f59f0b47ef21182d5f0fbc 145 Gene3D G3DSA:3.10.180.10 1 145 3.1E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_03350 3a8c46de47f59f0b47ef21182d5f0fbc 145 SUPERFAMILY SSF54593 6 144 2.4E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_27890 02541d414e14d89b35bc828b62031eca 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 184 1.5E-26 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_27890 02541d414e14d89b35bc828b62031eca 190 SUPERFAMILY SSF88946 12 112 2.51E-17 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_27890 02541d414e14d89b35bc828b62031eca 190 Pfam PF04542 Sigma-70 region 2 26 98 3.8E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_27890 02541d414e14d89b35bc828b62031eca 190 Gene3D G3DSA:1.10.10.10 111 188 5.3E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27890 02541d414e14d89b35bc828b62031eca 190 Pfam PF08281 Sigma-70, region 4 131 180 1.1E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UA74_27890 02541d414e14d89b35bc828b62031eca 190 Gene3D G3DSA:1.10.1740.10 6 96 5.8E-14 T 12-10-2018 UA74_27890 02541d414e14d89b35bc828b62031eca 190 SUPERFAMILY SSF88659 112 185 2.62E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_17270 84589695e567034695ecfa633fdad210 256 SUPERFAMILY SSF53335 29 235 5.85E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_17270 84589695e567034695ecfa633fdad210 256 Gene3D G3DSA:3.40.50.150 37 230 1.6E-32 T 12-10-2018 UA74_17270 84589695e567034695ecfa633fdad210 256 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 55 214 8.6E-36 T 12-10-2018 IPR006342 Methyltransferase FkbM UA74_17270 84589695e567034695ecfa633fdad210 256 Pfam PF05050 Methyltransferase FkbM domain 57 233 1.1E-21 T 12-10-2018 IPR006342 Methyltransferase FkbM UA74_07125 354792066d2806ddcd90c2782316d92a 429 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 223 233 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UA74_07125 354792066d2806ddcd90c2782316d92a 429 SUPERFAMILY SSF52743 153 412 4.71E-73 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_07125 354792066d2806ddcd90c2782316d92a 429 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 373 383 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UA74_07125 354792066d2806ddcd90c2782316d92a 429 Gene3D G3DSA:3.30.70.80 72 149 1.1E-14 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 UA74_07125 354792066d2806ddcd90c2782316d92a 429 PRINTS PR00723 Subtilisin serine protease family (S8) signature 219 232 2.3E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_07125 354792066d2806ddcd90c2782316d92a 429 PRINTS PR00723 Subtilisin serine protease family (S8) signature 181 200 2.3E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_07125 354792066d2806ddcd90c2782316d92a 429 PRINTS PR00723 Subtilisin serine protease family (S8) signature 372 388 2.3E-16 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related UA74_07125 354792066d2806ddcd90c2782316d92a 429 Gene3D G3DSA:3.40.50.200 153 429 1.0E-87 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UA74_07125 354792066d2806ddcd90c2782316d92a 429 Pfam PF05922 Peptidase inhibitor I9 107 150 4.3E-6 T 12-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 UA74_07125 354792066d2806ddcd90c2782316d92a 429 SUPERFAMILY SSF54897 80 150 2.1E-11 T 12-10-2018 UA74_07125 354792066d2806ddcd90c2782316d92a 429 Pfam PF00082 Subtilase family 188 405 1.2E-32 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UA74_07125 354792066d2806ddcd90c2782316d92a 429 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 186 197 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UA74_09600 181eb6c33380286c5c5c76f9b73be37c 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 123 1.0E-46 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 UA74_09600 181eb6c33380286c5c5c76f9b73be37c 143 Gene3D G3DSA:2.40.330.20 1 139 2.5E-44 T 12-10-2018 IPR038619 MraZ superfamily UA74_09600 181eb6c33380286c5c5c76f9b73be37c 143 SUPERFAMILY SSF89447 1 135 1.26E-45 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily UA74_09600 181eb6c33380286c5c5c76f9b73be37c 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 136 4.9E-19 T 12-10-2018 IPR020603 MraZ domain UA74_09600 181eb6c33380286c5c5c76f9b73be37c 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 4.8E-19 T 12-10-2018 IPR020603 MraZ domain UA74_09600 181eb6c33380286c5c5c76f9b73be37c 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 136 4.4E-36 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 UA74_09600 181eb6c33380286c5c5c76f9b73be37c 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 51.492 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 UA74_23980 a8fbfe1dfa504b92004bc1921f72d104 274 SUPERFAMILY SSF161098 77 258 5.89E-27 T 12-10-2018 IPR035906 MetI-like superfamily UA74_23980 a8fbfe1dfa504b92004bc1921f72d104 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 262 1.1E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_23980 a8fbfe1dfa504b92004bc1921f72d104 274 Gene3D G3DSA:1.10.3720.10 74 269 1.1E-20 T 12-10-2018 IPR035906 MetI-like superfamily UA74_29740 b7a8cd35f647df1b8d27c90b4c789ac0 285 SUPERFAMILY SSF49319 63 188 2.29E-12 T 12-10-2018 IPR027273 Neocarzinostatin-like UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 Pfam PF00574 Clp protease 19 192 2.9E-74 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 SUPERFAMILY SSF52096 21 193 5.39E-63 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 Gene3D G3DSA:3.90.226.10 7 196 1.2E-69 T 12-10-2018 UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 20 35 5.8E-43 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 91 108 5.8E-43 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 60 80 5.8E-43 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 112 131 5.8E-43 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 PRINTS PR00127 Clp protease catalytic subunit P signature 169 188 5.8E-43 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 113 126 - T 12-10-2018 IPR033135 ClpP, histidine active site UA74_18800 5063aa57e2964a1c1a2de55b53810795 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 194 38.975 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_25620 d7d11113d301ce82b02c57117581e8bf 196 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_25620 d7d11113d301ce82b02c57117581e8bf 196 Gene3D G3DSA:3.40.50.150 1 182 2.1E-54 T 12-10-2018 UA74_25620 d7d11113d301ce82b02c57117581e8bf 196 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 178 8.7E-47 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 UA74_25620 d7d11113d301ce82b02c57117581e8bf 196 SUPERFAMILY SSF53335 2 179 2.04E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_25620 d7d11113d301ce82b02c57117581e8bf 196 PIRSF PIRSF004553 1 183 1.8E-53 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 UA74_25620 d7d11113d301ce82b02c57117581e8bf 196 Pfam PF03602 Conserved hypothetical protein 95 2 178 5.8E-47 T 12-10-2018 UA74_18025 95e4755a621ea0a4d1ba93777ca799a0 215 Pfam PF01738 Dienelactone hydrolase family 89 211 6.0E-6 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 UA74_18025 95e4755a621ea0a4d1ba93777ca799a0 215 SUPERFAMILY SSF53474 5 213 2.11E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18025 95e4755a621ea0a4d1ba93777ca799a0 215 Gene3D G3DSA:3.40.50.1820 2 214 8.3E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19255 9b17561a1e0d48acc13b1ec7b4534fc0 840 SUPERFAMILY SSF82866 238 430 4.19E-25 T 12-10-2018 UA74_19255 9b17561a1e0d48acc13b1ec7b4534fc0 840 Gene3D G3DSA:1.20.1640.10 597 787 8.2E-7 T 12-10-2018 UA74_19255 9b17561a1e0d48acc13b1ec7b4534fc0 840 Pfam PF03176 MMPL family 181 438 1.3E-38 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UA74_19255 9b17561a1e0d48acc13b1ec7b4534fc0 840 Pfam PF03176 MMPL family 523 789 2.3E-32 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UA74_19255 9b17561a1e0d48acc13b1ec7b4534fc0 840 SUPERFAMILY SSF82866 547 788 2.75E-28 T 12-10-2018 UA74_16915 1e08ef5ef6f4299e21ebe0c95b1d7dd9 154 Gene3D G3DSA:1.20.120.1630 2 142 4.4E-10 T 12-10-2018 UA74_16915 1e08ef5ef6f4299e21ebe0c95b1d7dd9 154 Pfam PF04191 Phospholipid methyltransferase 30 127 6.3E-5 T 12-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 UA74_29470 2562127a6c82e52b814844f65607a28d 95 Pfam PF03795 YCII-related domain 12 85 1.5E-13 T 12-10-2018 IPR005545 YCII-related UA74_29470 2562127a6c82e52b814844f65607a28d 95 Gene3D G3DSA:3.30.70.1060 6 88 3.8E-13 T 12-10-2018 UA74_29470 2562127a6c82e52b814844f65607a28d 95 SUPERFAMILY SSF54909 1 87 1.36E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_04960 881443ab03a6ab1fa5b029ff1dc6f656 109 SUPERFAMILY SSF46785 1 97 3.94E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04960 881443ab03a6ab1fa5b029ff1dc6f656 109 Gene3D G3DSA:1.10.10.10 1 103 5.7E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04960 881443ab03a6ab1fa5b029ff1dc6f656 109 SMART SM00418 3 81 1.2E-24 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_04960 881443ab03a6ab1fa5b029ff1dc6f656 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.4E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_04960 881443ab03a6ab1fa5b029ff1dc6f656 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.4E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_04960 881443ab03a6ab1fa5b029ff1dc6f656 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.4E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_04960 881443ab03a6ab1fa5b029ff1dc6f656 109 Pfam PF01022 Bacterial regulatory protein, arsR family 11 55 1.0E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_25430 eb3112f90de983bbcb33147fda8ccdee 412 SUPERFAMILY SSF53901 214 406 3.05E-62 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_25430 eb3112f90de983bbcb33147fda8ccdee 412 SMART SM00825 Beta-ketoacyl synthase 6 399 4.4E-14 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_25430 eb3112f90de983bbcb33147fda8ccdee 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 365 6.1E-33 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_25430 eb3112f90de983bbcb33147fda8ccdee 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site UA74_25430 eb3112f90de983bbcb33147fda8ccdee 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 244 8.1E-55 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_25430 eb3112f90de983bbcb33147fda8ccdee 412 Gene3D G3DSA:3.40.47.10 259 406 8.2E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_25430 eb3112f90de983bbcb33147fda8ccdee 412 Gene3D G3DSA:3.40.47.10 1 255 6.1E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_25430 eb3112f90de983bbcb33147fda8ccdee 412 SUPERFAMILY SSF53901 4 251 1.26E-65 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_25270 067fce5bc157673f0b62d30508d8bc74 408 Pfam PF00155 Aminotransferase class I and II 99 398 1.4E-23 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_25270 067fce5bc157673f0b62d30508d8bc74 408 Gene3D G3DSA:3.90.1150.10 77 398 1.6E-80 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_25270 067fce5bc157673f0b62d30508d8bc74 408 SUPERFAMILY SSF53383 74 399 5.78E-55 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_25270 067fce5bc157673f0b62d30508d8bc74 408 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 257 270 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UA74_25270 067fce5bc157673f0b62d30508d8bc74 408 Gene3D G3DSA:3.40.640.10 89 305 1.6E-80 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_12905 4bf9e053eb1a3e5476d66aecaf46841d 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 2.3E-235 T 12-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 UA74_12905 4bf9e053eb1a3e5476d66aecaf46841d 452 Pfam PF03136 Pup-ligase protein 4 422 2.7E-156 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 UA74_12905 4bf9e053eb1a3e5476d66aecaf46841d 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 50.679 T 12-10-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 MetaCyc: PWY-7893 UA74_12905 4bf9e053eb1a3e5476d66aecaf46841d 452 PIRSF PIRSF018077 1 452 1.4E-181 T 12-10-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 MetaCyc: PWY-7893 UA74_08400 510b268cc029b8267e91ca4a081fa68b 307 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 98 251 3.5E-25 T 12-10-2018 IPR006342 Methyltransferase FkbM UA74_08400 510b268cc029b8267e91ca4a081fa68b 307 SUPERFAMILY SSF53335 72 282 4.39E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_08400 510b268cc029b8267e91ca4a081fa68b 307 Pfam PF05050 Methyltransferase FkbM domain 101 275 1.4E-17 T 12-10-2018 IPR006342 Methyltransferase FkbM UA74_08400 510b268cc029b8267e91ca4a081fa68b 307 Gene3D G3DSA:3.40.50.150 79 279 5.9E-31 T 12-10-2018 UA74_06355 5f014d25bea37b14b1684d305da39684 171 Gene3D G3DSA:3.30.1310.10 22 122 2.4E-9 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_06355 5f014d25bea37b14b1684d305da39684 171 Pfam PF02575 YbaB/EbfC DNA-binding family 28 112 7.5E-11 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_06355 5f014d25bea37b14b1684d305da39684 171 SUPERFAMILY SSF82607 24 112 1.7E-6 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_02820 15285f2ea348502f24f971f3589d7e8d 413 Gene3D G3DSA:3.40.640.10 78 300 3.9E-132 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_02820 15285f2ea348502f24f971f3589d7e8d 413 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 250 263 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UA74_02820 15285f2ea348502f24f971f3589d7e8d 413 Gene3D G3DSA:3.90.1150.10 40 405 3.9E-132 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_02820 15285f2ea348502f24f971f3589d7e8d 413 Pfam PF00155 Aminotransferase class I and II 46 399 1.3E-73 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_02820 15285f2ea348502f24f971f3589d7e8d 413 SUPERFAMILY SSF53383 17 410 2.15E-111 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_15325 0a6d4708336cc1f4f0478ab99a370f83 120 SMART SM00422 1 69 1.4E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15325 0a6d4708336cc1f4f0478ab99a370f83 120 Pfam PF13411 MerR HTH family regulatory protein 1 67 6.3E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15325 0a6d4708336cc1f4f0478ab99a370f83 120 SUPERFAMILY SSF46955 1 112 5.13E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_15325 0a6d4708336cc1f4f0478ab99a370f83 120 Gene3D G3DSA:1.10.1660.10 1 117 2.0E-31 T 12-10-2018 UA74_15325 0a6d4708336cc1f4f0478ab99a370f83 120 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15325 0a6d4708336cc1f4f0478ab99a370f83 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.0E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15325 0a6d4708336cc1f4f0478ab99a370f83 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.0E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15325 0a6d4708336cc1f4f0478ab99a370f83 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.0E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_18435 bebaccb033142cb26ddcee37496eb21c 187 SUPERFAMILY SSF46689 3 80 5.49E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_18435 bebaccb033142cb26ddcee37496eb21c 187 Gene3D G3DSA:1.10.357.10 1 187 4.6E-48 T 12-10-2018 UA74_18435 bebaccb033142cb26ddcee37496eb21c 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 2.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_18435 bebaccb033142cb26ddcee37496eb21c 187 SUPERFAMILY SSF48498 80 185 6.37E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_14895 b6f3937759d32da43759a75de969a1d2 161 Gene3D G3DSA:1.10.10.10 4 146 2.0E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14895 b6f3937759d32da43759a75de969a1d2 161 SMART SM00347 36 136 1.7E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14895 b6f3937759d32da43759a75de969a1d2 161 SUPERFAMILY SSF46785 17 144 3.99E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14895 b6f3937759d32da43759a75de969a1d2 161 Pfam PF12802 MarR family 45 100 1.2E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_07615 853591b8864851b8d1b8f7da5f630322 538 Pfam PF00135 Carboxylesterase family 39 518 7.9E-100 T 12-10-2018 IPR002018 Carboxylesterase, type B UA74_07615 853591b8864851b8d1b8f7da5f630322 538 SUPERFAMILY SSF53474 40 511 1.46E-107 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07615 853591b8864851b8d1b8f7da5f630322 538 Gene3D G3DSA:3.40.50.1820 34 538 7.1E-136 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_05250 329e2caf3584e627c4b8847a83f51175 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 196 4.9E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05250 329e2caf3584e627c4b8847a83f51175 206 SUPERFAMILY SSF46894 133 204 1.63E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_05250 329e2caf3584e627c4b8847a83f51175 206 SMART SM00421 142 199 1.8E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05250 329e2caf3584e627c4b8847a83f51175 206 SMART SM00448 2 115 6.8E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_05250 329e2caf3584e627c4b8847a83f51175 206 Pfam PF00072 Response regulator receiver domain 5 115 4.3E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_05250 329e2caf3584e627c4b8847a83f51175 206 SUPERFAMILY SSF52172 1 134 1.22E-34 T 12-10-2018 IPR011006 CheY-like superfamily UA74_05250 329e2caf3584e627c4b8847a83f51175 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 1.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05250 329e2caf3584e627c4b8847a83f51175 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 1.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05250 329e2caf3584e627c4b8847a83f51175 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 1.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05250 329e2caf3584e627c4b8847a83f51175 206 Gene3D G3DSA:3.40.50.12740 2 205 1.2E-66 T 12-10-2018 UA74_03445 d19c1e274fa8d6f13c7e19de162a7a44 373 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 11 215 2.3E-26 T 12-10-2018 UA74_03445 d19c1e274fa8d6f13c7e19de162a7a44 373 Gene3D G3DSA:3.40.50.150 8 234 3.5E-47 T 12-10-2018 UA74_03445 d19c1e274fa8d6f13c7e19de162a7a44 373 SUPERFAMILY SSF53335 4 199 1.08E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_24520 e2c3b54d3fa207b0bd8aee73d76f09c2 398 SUPERFAMILY SSF102114 12 397 1.7E-102 T 12-10-2018 UA74_24520 e2c3b54d3fa207b0bd8aee73d76f09c2 398 Pfam PF04055 Radical SAM superfamily 24 199 1.9E-19 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_24520 e2c3b54d3fa207b0bd8aee73d76f09c2 398 Gene3D G3DSA:3.80.30.20 6 323 3.5E-89 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UA74_24520 e2c3b54d3fa207b0bd8aee73d76f09c2 398 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 22 356 4.1E-68 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 UA74_24520 e2c3b54d3fa207b0bd8aee73d76f09c2 398 SMART SM00729 19 244 5.9E-57 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_12015 e605c3c5e2a03abca7b2dec13a5d96cb 599 Pfam PF04183 IucA / IucC family 140 387 6.6E-73 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 UA74_12015 e605c3c5e2a03abca7b2dec13a5d96cb 599 Gene3D G3DSA:1.10.510.40 376 578 1.1E-47 T 12-10-2018 UA74_12015 e605c3c5e2a03abca7b2dec13a5d96cb 599 Gene3D G3DSA:1.10.274.90 3 127 1.7E-21 T 12-10-2018 UA74_12015 e605c3c5e2a03abca7b2dec13a5d96cb 599 Pfam PF06276 Ferric iron reductase FhuF-like transporter 409 560 3.8E-31 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain UA74_06365 32bc85eeea6f08b4691288f4c9015ea8 259 Gene3D G3DSA:1.10.12.10 199 258 1.8E-16 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal UA74_06365 32bc85eeea6f08b4691288f4c9015ea8 259 SUPERFAMILY SSF52096 3 255 7.91E-78 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_06365 32bc85eeea6f08b4691288f4c9015ea8 259 Gene3D G3DSA:3.90.226.10 1 198 4.5E-69 T 12-10-2018 UA74_06365 32bc85eeea6f08b4691288f4c9015ea8 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 251 9.5E-66 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UA74_01990 5dc7cd0b979e63a673a5a7c4c99c2717 507 SUPERFAMILY SSF51445 13 337 5.26E-74 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_01990 5dc7cd0b979e63a673a5a7c4c99c2717 507 PRINTS PR00133 Glycosyl hydrolase family 3 signature 166 182 2.6E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_01990 5dc7cd0b979e63a673a5a7c4c99c2717 507 PRINTS PR00133 Glycosyl hydrolase family 3 signature 88 107 2.6E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_01990 5dc7cd0b979e63a673a5a7c4c99c2717 507 PRINTS PR00133 Glycosyl hydrolase family 3 signature 241 259 2.6E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_01990 5dc7cd0b979e63a673a5a7c4c99c2717 507 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 34 337 7.5E-71 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UA74_01990 5dc7cd0b979e63a673a5a7c4c99c2717 507 Gene3D G3DSA:3.20.20.300 4 339 1.6E-95 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 UA74_26405 35d63f4f2db30f1dce31ea2c69264e94 189 Pfam PF00583 Acetyltransferase (GNAT) family 48 162 3.2E-13 T 12-10-2018 IPR000182 GNAT domain UA74_26405 35d63f4f2db30f1dce31ea2c69264e94 189 SUPERFAMILY SSF55729 25 173 3.95E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_26405 35d63f4f2db30f1dce31ea2c69264e94 189 Gene3D G3DSA:3.40.630.30 7 189 4.0E-39 T 12-10-2018 UA74_22420 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 321 336 1.8E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 275 286 1.8E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 93 104 1.8E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 159 174 1.8E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 344 353 1.8E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 353 364 1.8E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 293 320 1.8E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 142 158 1.8E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 PRINTS PR00359 B-class P450 signature 194 216 1.8E-45 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 SUPERFAMILY SSF48264 17 401 1.26E-79 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 Pfam PF00067 Cytochrome P450 209 375 6.5E-16 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_22420 52849095b1c13cbee502e91d259231a9 411 Gene3D G3DSA:1.10.630.10 4 407 2.2E-107 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20930 53e857a2488b2d9b4ba6fe96e9878dac 359 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 10 203 2.4E-29 T 12-10-2018 UA74_20930 53e857a2488b2d9b4ba6fe96e9878dac 359 Gene3D G3DSA:3.40.50.150 8 215 6.4E-53 T 12-10-2018 UA74_20930 53e857a2488b2d9b4ba6fe96e9878dac 359 SUPERFAMILY SSF53335 7 203 4.27E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 Pfam PF04055 Radical SAM superfamily 167 336 6.0E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 2 452 1.5E-118 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 SUPERFAMILY SSF102114 132 382 3.27E-45 T 12-10-2018 UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 1 455 57.43 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 164 184 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 Pfam PF00919 Uncharacterized protein family UPF0004 2 94 1.4E-26 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 SMART SM00729 160 378 8.0E-39 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 448 5.7E-100 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 Gene3D G3DSA:2.40.50.140 393 458 2.0E-7 T 12-10-2018 UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 Gene3D G3DSA:3.80.30.20 157 392 5.1E-66 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UA74_09530 2f9f56c25450cbc613cba7b5e035a5c1 465 Gene3D G3DSA:3.40.50.12160 1 123 1.5E-30 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily UA74_03300 1f19e630bb18816b056168f77622c1b4 198 SUPERFAMILY SSF54593 5 125 1.97E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_03300 1f19e630bb18816b056168f77622c1b4 198 Gene3D G3DSA:3.10.180.10 2 130 3.9E-42 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_16610 ab44423f90c104da9efaa06cde5dbd68 341 Pfam PF01794 Ferric reductase like transmembrane component 95 230 1.5E-11 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain UA74_26040 f9485fa1f6bce9db85c011c8a986f5b8 505 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 13 489 91.586 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_26040 f9485fa1f6bce9db85c011c8a986f5b8 505 PIRSF PIRSF001221 4 454 1.3E-43 T 12-10-2018 UA74_26040 f9485fa1f6bce9db85c011c8a986f5b8 505 PIRSF PIRSF001221 454 489 2.4 T 12-10-2018 UA74_26040 f9485fa1f6bce9db85c011c8a986f5b8 505 Gene3D G3DSA:3.90.1300.10 5 494 6.5E-186 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_26040 f9485fa1f6bce9db85c011c8a986f5b8 505 Pfam PF01425 Amidase 26 476 9.5E-159 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_26040 f9485fa1f6bce9db85c011c8a986f5b8 505 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 15 486 6.0E-188 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_26040 f9485fa1f6bce9db85c011c8a986f5b8 505 SUPERFAMILY SSF75304 4 485 5.1E-158 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UA74_26040 f9485fa1f6bce9db85c011c8a986f5b8 505 ProSitePatterns PS00571 Amidases signature. 155 186 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 UA74_10690 2f61c44bffd795e647a38692490e06a8 187 Pfam PF04167 Protein of unknown function (DUF402) 60 127 1.3E-9 T 12-10-2018 IPR007295 Domain of unknown function DUF402 UA74_10690 2f61c44bffd795e647a38692490e06a8 187 SUPERFAMILY SSF159234 12 173 6.28E-40 T 12-10-2018 IPR035930 FomD-like superfamily UA74_10690 2f61c44bffd795e647a38692490e06a8 187 Gene3D G3DSA:2.40.380.10 3 172 1.5E-61 T 12-10-2018 IPR035930 FomD-like superfamily UA74_17895 ab4f6f01884a01a5602c841e3b4617e6 208 Pfam PF03358 NADPH-dependent FMN reductase 6 156 3.5E-34 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_17895 ab4f6f01884a01a5602c841e3b4617e6 208 SUPERFAMILY SSF52218 6 180 2.1E-27 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_17895 ab4f6f01884a01a5602c841e3b4617e6 208 Gene3D G3DSA:3.40.50.360 2 182 1.2E-47 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_17895 ab4f6f01884a01a5602c841e3b4617e6 208 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 6 202 6.3E-86 T 12-10-2018 IPR023932 Uncharacterised protein family, CE1759 UA74_22410 14567f5ef24a7e413b6b93790f9cb893 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 14 162 1.6E-17 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UA74_22410 14567f5ef24a7e413b6b93790f9cb893 297 Gene3D G3DSA:3.40.50.720 5 166 1.0E-32 T 12-10-2018 UA74_22410 14567f5ef24a7e413b6b93790f9cb893 297 PIRSF PIRSF000103 7 297 1.4E-26 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_22410 14567f5ef24a7e413b6b93790f9cb893 297 SUPERFAMILY SSF51735 13 161 1.1E-24 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22410 14567f5ef24a7e413b6b93790f9cb893 297 Gene3D G3DSA:1.10.1040.10 169 297 6.5E-35 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_28145 08569238c55026001a4de86e82b65e77 242 Pfam PF14016 Protein of unknown function (DUF4232) 107 234 9.6E-26 T 12-10-2018 IPR025326 Protein of unknown function DUF4232 UA74_13095 309b6d01d0246bbbbb2905d2aa84556e 65 Pfam PF04149 Domain of unknown function (DUF397) 9 58 1.7E-8 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_23635 bf498da1e420c78552927e8571d13876 271 Gene3D G3DSA:3.40.430.10 21 270 6.5E-65 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_23635 bf498da1e420c78552927e8571d13876 271 Pfam PF01872 RibD C-terminal domain 48 237 8.4E-33 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_23635 bf498da1e420c78552927e8571d13876 271 SUPERFAMILY SSF53597 46 261 4.35E-44 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_11170 001460fc81f1a09fc1cd3ba25d9e01a7 450 PIRSF PIRSF000521 3 449 8.6E-149 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_11170 001460fc81f1a09fc1cd3ba25d9e01a7 450 TIGRFAM TIGR03251 LAT_fam: L-lysine 6-transaminase 15 446 2.3E-208 T 12-10-2018 IPR017657 L-lysine 6-transaminase GO:0017000|GO:0030170|GO:0045484 MetaCyc: PWY-5298 UA74_11170 001460fc81f1a09fc1cd3ba25d9e01a7 450 Pfam PF00202 Aminotransferase class-III 33 445 1.7E-78 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_11170 001460fc81f1a09fc1cd3ba25d9e01a7 450 Gene3D G3DSA:3.90.1150.10 39 442 5.0E-136 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_11170 001460fc81f1a09fc1cd3ba25d9e01a7 450 Gene3D G3DSA:3.40.640.10 70 353 5.0E-136 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_11170 001460fc81f1a09fc1cd3ba25d9e01a7 450 SUPERFAMILY SSF53383 37 446 3.17E-79 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 412 53.813 T 12-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 3.8E-24 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 3.8E-24 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 213 231 3.8E-24 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 244 265 3.8E-24 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 37 332 4.5E-81 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 3 412 2.9E-207 T 12-10-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 Gene3D G3DSA:1.20.120.640 330 412 6.1E-24 T 12-10-2018 UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 Gene3D G3DSA:3.40.50.620 1 329 1.9E-103 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_14095 39c01b3706342bbe4fa4a375ac986d2b 412 SUPERFAMILY SSF52374 31 334 2.65E-68 T 12-10-2018 UA74_21120 8347d97de65d3e0371c776e23380a2cf 317 SUPERFAMILY SSF53613 5 308 6.24E-76 T 12-10-2018 IPR029056 Ribokinase-like UA74_21120 8347d97de65d3e0371c776e23380a2cf 317 Gene3D G3DSA:3.40.1190.20 4 315 2.4E-88 T 12-10-2018 IPR029056 Ribokinase-like UA74_21120 8347d97de65d3e0371c776e23380a2cf 317 Pfam PF00294 pfkB family carbohydrate kinase 8 301 5.4E-60 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_21120 8347d97de65d3e0371c776e23380a2cf 317 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 253 266 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_28945 edd66d3fd3eef551f3032e0d4ccf0d5d 206 Pfam PF06197 Protein of unknown function (DUF998) 16 201 1.1E-37 T 12-10-2018 IPR009339 Protein of unknown function DUF998 UA74_16420 86de46694e449865534129486ef20775 416 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 247 386 8.1E-11 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 UA74_16420 86de46694e449865534129486ef20775 416 SUPERFAMILY SSF53756 20 411 8.03E-68 T 12-10-2018 UA74_16420 86de46694e449865534129486ef20775 416 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 24 407 5.8E-106 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 UA74_16420 86de46694e449865534129486ef20775 416 Gene3D G3DSA:3.40.50.2000 234 395 1.2E-121 T 12-10-2018 UA74_16420 86de46694e449865534129486ef20775 416 Gene3D G3DSA:3.40.50.2000 22 405 1.2E-121 T 12-10-2018 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 13 815 0.0 T 12-10-2018 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Gene3D G3DSA:1.10.268.10 378 466 2.5E-199 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 SUPERFAMILY SSF101904 507 822 3.66E-99 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Gene3D G3DSA:3.90.199.10 36 495 2.5E-199 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Gene3D G3DSA:3.30.1360.40 244 341 2.5E-199 T 12-10-2018 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 SUPERFAMILY SSF56719 35 495 4.97E-169 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 480 3.1E-149 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Gene3D G3DSA:2.120.10.90 509 817 4.9E-123 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 769 809 1.6E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 619 663 2.5E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 720 766 4.2E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 666 714 1.5E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 562 608 1.6E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 512 559 1.2E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 SMART SM00434 15 473 2.1E-272 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UA74_00035 3f26ee0d0f150de9ffbffed91c2a5e83 850 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 8 817 23.38 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UA74_24800 8521429f15c0e7c39759ca702ab74806 248 SUPERFAMILY SSF82771 43 77 2.35E-6 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UA74_24800 8521429f15c0e7c39759ca702ab74806 248 Pfam PF01541 GIY-YIG catalytic domain 43 89 7.8E-5 T 12-10-2018 IPR000305 GIY-YIG endonuclease UA74_24800 8521429f15c0e7c39759ca702ab74806 248 Gene3D G3DSA:3.40.1440.10 30 112 1.3E-6 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UA74_23900 edcf90f69f8b2833a5d9e89925b5e2f2 102 Pfam PF02575 YbaB/EbfC DNA-binding family 14 93 2.8E-6 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_23900 edcf90f69f8b2833a5d9e89925b5e2f2 102 SUPERFAMILY SSF82607 13 95 2.22E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_23900 edcf90f69f8b2833a5d9e89925b5e2f2 102 Gene3D G3DSA:3.30.1310.10 7 101 1.1E-6 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_16695 4f167c6feb0969c5c13069a2df32cf06 253 SMART SM01134 73 234 6.8E-70 T 12-10-2018 UA74_16695 4f167c6feb0969c5c13069a2df32cf06 253 SUPERFAMILY SSF46785 5 60 2.77E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_16695 4f167c6feb0969c5c13069a2df32cf06 253 SUPERFAMILY SSF100950 74 235 1.99E-29 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_16695 4f167c6feb0969c5c13069a2df32cf06 253 Pfam PF00455 DeoR C terminal sensor domain 75 233 6.0E-50 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain UA74_16695 4f167c6feb0969c5c13069a2df32cf06 253 SMART SM00420 6 58 7.3E-12 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_16695 4f167c6feb0969c5c13069a2df32cf06 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 6.0E-13 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_16695 4f167c6feb0969c5c13069a2df32cf06 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.3E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_16695 4f167c6feb0969c5c13069a2df32cf06 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.3E-7 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_26105 fefed8aa896bb1d4ccfb6de57b0a57af 280 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 271 1.6E-63 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_26105 fefed8aa896bb1d4ccfb6de57b0a57af 280 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 15 28 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 UA74_26105 fefed8aa896bb1d4ccfb6de57b0a57af 280 SUPERFAMILY SSF53686 6 277 1.7E-67 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_26105 fefed8aa896bb1d4ccfb6de57b0a57af 280 Gene3D G3DSA:3.40.50.1100 7 276 3.9E-81 T 12-10-2018 UA74_26105 fefed8aa896bb1d4ccfb6de57b0a57af 280 Gene3D G3DSA:3.40.50.1100 23 116 3.9E-81 T 12-10-2018 UA74_14085 9f3e973fa43df858348ae56bc28b2708 333 Gene3D G3DSA:1.20.1530.20 14 317 3.7E-21 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily UA74_14085 9f3e973fa43df858348ae56bc28b2708 333 Pfam PF01758 Sodium Bile acid symporter family 47 218 1.6E-11 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 UA74_24025 1db1959ba74bd90660297fab8f442e46 423 Gene3D G3DSA:2.30.40.10 17 418 3.8E-107 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_24025 1db1959ba74bd90660297fab8f442e46 423 Gene3D G3DSA:3.20.20.140 53 363 3.8E-107 T 12-10-2018 UA74_24025 1db1959ba74bd90660297fab8f442e46 423 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 420 8.5E-99 T 12-10-2018 UA74_24025 1db1959ba74bd90660297fab8f442e46 423 Pfam PF01979 Amidohydrolase family 48 418 1.3E-11 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_24025 1db1959ba74bd90660297fab8f442e46 423 SUPERFAMILY SSF51556 52 362 2.76E-82 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_24025 1db1959ba74bd90660297fab8f442e46 423 ProSitePatterns PS00483 Dihydroorotase signature 2. 298 309 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UA74_24025 1db1959ba74bd90660297fab8f442e46 423 SUPERFAMILY SSF51338 13 421 8.06E-13 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_10720 f10798d861752444be9b57ce21cfd732 461 Pfam PF01979 Amidohydrolase family 98 452 2.3E-51 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_10720 f10798d861752444be9b57ce21cfd732 461 SUPERFAMILY SSF51338 41 455 1.01E-17 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_10720 f10798d861752444be9b57ce21cfd732 461 Gene3D G3DSA:3.20.20.140 103 413 5.9E-120 T 12-10-2018 UA74_10720 f10798d861752444be9b57ce21cfd732 461 Gene3D G3DSA:2.30.40.10 47 450 5.9E-120 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_10720 f10798d861752444be9b57ce21cfd732 461 SUPERFAMILY SSF51556 102 408 5.19E-95 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_14110 6afb9796d28ea372063ff4cb763f5f04 107 Gene3D G3DSA:1.10.3730.20 1 107 8.7E-30 T 12-10-2018 UA74_14110 6afb9796d28ea372063ff4cb763f5f04 107 Pfam PF00893 Small Multidrug Resistance protein 2 93 4.3E-22 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 UA74_14110 6afb9796d28ea372063ff4cb763f5f04 107 SUPERFAMILY SSF103481 6 104 1.2E-13 T 12-10-2018 UA74_08680 db4f81f8b76361637399f5803b520ff8 239 SUPERFAMILY SSF46689 15 74 9.98E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_08680 db4f81f8b76361637399f5803b520ff8 239 Gene3D G3DSA:1.10.357.10 64 203 3.6E-35 T 12-10-2018 UA74_08680 db4f81f8b76361637399f5803b520ff8 239 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 191 2.1E-26 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_08680 db4f81f8b76361637399f5803b520ff8 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 68 5.0E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_08680 db4f81f8b76361637399f5803b520ff8 239 Gene3D G3DSA:1.10.10.60 14 62 1.0E-20 T 12-10-2018 UA74_08680 db4f81f8b76361637399f5803b520ff8 239 SUPERFAMILY SSF48498 82 199 3.43E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_02725 76676a84189003198b94447fa047d72b 209 Pfam PF13521 AAA domain 37 200 1.4E-40 T 12-10-2018 IPR038727 NadR/Ttd14, AAA domain UA74_02725 76676a84189003198b94447fa047d72b 209 SUPERFAMILY SSF52540 34 206 7.14E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16945 92a65df799cd80868eb13ed5c3ba8cd0 709 Gene3D G3DSA:3.30.420.40 3 100 9.2E-6 T 12-10-2018 UA74_16945 92a65df799cd80868eb13ed5c3ba8cd0 709 Pfam PF01968 Hydantoinase/oxoprolinase 194 501 3.3E-72 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 UA74_16945 92a65df799cd80868eb13ed5c3ba8cd0 709 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 7 174 7.0E-27 T 12-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 UA74_16945 92a65df799cd80868eb13ed5c3ba8cd0 709 SUPERFAMILY SSF53067 7 495 2.16E-12 T 12-10-2018 UA74_12785 f617f1313e13aeb7e120a151ec0c3c93 510 Pfam PF07690 Major Facilitator Superfamily 9 355 8.7E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_12785 f617f1313e13aeb7e120a151ec0c3c93 510 Gene3D G3DSA:1.20.1250.20 1 394 7.5E-33 T 12-10-2018 UA74_12785 f617f1313e13aeb7e120a151ec0c3c93 510 SUPERFAMILY SSF103473 2 395 2.09E-38 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 Pfam PF13191 AAA ATPase domain 299 500 2.0E-19 T 12-10-2018 UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 SMART SM00862 16 95 4.8E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 SUPERFAMILY SSF52540 299 577 6.77E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 SUPERFAMILY SSF46894 4 95 1.56E-9 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 SMART SM01043 102 247 7.2E-49 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 95 1.4E-5 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 SUPERFAMILY SSF48452 98 269 5.14E-37 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 Gene3D G3DSA:1.25.40.10 100 265 1.5E-46 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 Gene3D G3DSA:1.10.10.10 1 97 2.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26230 a96a14058bccbca35e8127cc4bed4307 1176 Pfam PF03704 Bacterial transcriptional activator domain 102 247 1.3E-40 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_19385 c1878fe2aeafbdc4f9f988eda683961a 375 Gene3D G3DSA:1.10.3470.10 48 374 4.1E-82 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_19385 c1878fe2aeafbdc4f9f988eda683961a 375 Pfam PF01032 FecCD transport family 60 368 3.9E-75 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_19385 c1878fe2aeafbdc4f9f988eda683961a 375 SUPERFAMILY SSF81345 41 368 1.44E-67 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_11455 6eaf13a1abc27e8efac0a363eab645f7 325 PIRSF PIRSF018005 3 325 1.2E-120 T 12-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 UA74_11455 6eaf13a1abc27e8efac0a363eab645f7 325 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 22 321 4.3E-108 T 12-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 UA74_11455 6eaf13a1abc27e8efac0a363eab645f7 325 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 21 323 5.6E-108 T 12-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent UA74_11455 6eaf13a1abc27e8efac0a363eab645f7 325 SUPERFAMILY SSF53335 75 317 5.35E-11 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_11455 6eaf13a1abc27e8efac0a363eab645f7 325 Gene3D G3DSA:3.40.50.150 48 221 1.6E-52 T 12-10-2018 UA74_11455 6eaf13a1abc27e8efac0a363eab645f7 325 Gene3D G3DSA:3.40.50.150 271 324 1.6E-7 T 12-10-2018 UA74_11455 6eaf13a1abc27e8efac0a363eab645f7 325 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 8 324 53.954 T 12-10-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 UA74_30290 f2aef90fc70530cb2a58e8aa5cc4ff3e 276 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 73 242 9.1E-40 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UA74_30290 f2aef90fc70530cb2a58e8aa5cc4ff3e 276 PIRSF PIRSF003078 49 261 4.8E-45 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UA74_30290 f2aef90fc70530cb2a58e8aa5cc4ff3e 276 Pfam PF02527 rRNA small subunit methyltransferase G 70 245 4.8E-50 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UA74_30290 f2aef90fc70530cb2a58e8aa5cc4ff3e 276 SUPERFAMILY SSF53335 72 226 2.74E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_30290 f2aef90fc70530cb2a58e8aa5cc4ff3e 276 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 60 241 25.046 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UA74_30290 f2aef90fc70530cb2a58e8aa5cc4ff3e 276 Gene3D G3DSA:3.40.50.150 53 276 1.8E-58 T 12-10-2018 UA74_05195 39cc86a76bc100be9fb6569745902f5d 374 Gene3D G3DSA:3.40.640.10 54 272 1.0E-102 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_05195 39cc86a76bc100be9fb6569745902f5d 374 Gene3D G3DSA:3.90.1150.10 21 356 1.0E-102 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_05195 39cc86a76bc100be9fb6569745902f5d 374 Pfam PF00155 Aminotransferase class I and II 45 353 9.7E-39 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_05195 39cc86a76bc100be9fb6569745902f5d 374 SUPERFAMILY SSF53383 39 369 6.12E-73 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_20915 34b91e23bbf9af0265ba916a146017e5 155 Gene3D G3DSA:1.10.10.10 10 119 1.7E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14595 03bcffc5b9e88f60a42a1174b1f6db7e 188 Gene3D G3DSA:3.40.630.30 22 184 1.1E-32 T 12-10-2018 UA74_14595 03bcffc5b9e88f60a42a1174b1f6db7e 188 Pfam PF13302 Acetyltransferase (GNAT) domain 36 168 8.8E-19 T 12-10-2018 IPR000182 GNAT domain UA74_14595 03bcffc5b9e88f60a42a1174b1f6db7e 188 SUPERFAMILY SSF55729 27 172 3.67E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_00555 a5251f1f824bb395aecfeb3d1897c1d5 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 206 3.6E-63 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UA74_00555 a5251f1f824bb395aecfeb3d1897c1d5 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 9.1E-98 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UA74_00555 a5251f1f824bb395aecfeb3d1897c1d5 335 PIRSF PIRSF000267 1 332 9.3E-106 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UA74_16235 dd973a8e47dfc008c6b0be16a61bca5a 841 SUPERFAMILY SSF52540 397 760 1.72E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16235 dd973a8e47dfc008c6b0be16a61bca5a 841 Pfam PF12696 TraM recognition site of TraD and TraG 679 749 7.2E-5 T 12-10-2018 IPR032689 TraD/TraG, TraM recognition site UA74_16235 dd973a8e47dfc008c6b0be16a61bca5a 841 Gene3D G3DSA:3.40.50.300 408 499 5.8E-11 T 12-10-2018 UA74_16235 dd973a8e47dfc008c6b0be16a61bca5a 841 Pfam PF01935 Domain of unknown function DUF87 420 494 8.4E-7 T 12-10-2018 IPR002789 Helicase HerA, central domain UA74_16235 dd973a8e47dfc008c6b0be16a61bca5a 841 Gene3D G3DSA:3.40.50.300 588 760 2.7E-17 T 12-10-2018 UA74_30205 f06220e689541e08201f3f2bc82de516 193 SUPERFAMILY SSF143456 9 187 8.63E-47 T 12-10-2018 UA74_30205 f06220e689541e08201f3f2bc82de516 193 Pfam PF02622 Uncharacterized ACR, COG1678 20 176 1.8E-35 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 UA74_30205 f06220e689541e08201f3f2bc82de516 193 Gene3D G3DSA:3.40.1740.10 3 184 2.9E-59 T 12-10-2018 UA74_30205 f06220e689541e08201f3f2bc82de516 193 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 9 190 24.543 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 UA74_05375 298da69ddbc4dcd629fff807f4e407dc 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 5.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05375 298da69ddbc4dcd629fff807f4e407dc 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05375 298da69ddbc4dcd629fff807f4e407dc 193 Gene3D G3DSA:1.10.357.10 1 191 3.1E-51 T 12-10-2018 UA74_05375 298da69ddbc4dcd629fff807f4e407dc 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 2.8E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05375 298da69ddbc4dcd629fff807f4e407dc 193 SUPERFAMILY SSF46689 6 85 9.45E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_05375 298da69ddbc4dcd629fff807f4e407dc 193 SUPERFAMILY SSF48498 85 184 2.58E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_00840 82f546d8207ea756fe368f8e16e54421 399 Pfam PF00108 Thiolase, N-terminal domain 5 268 1.3E-55 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UA74_00840 82f546d8207ea756fe368f8e16e54421 399 PIRSF PIRSF000429 1 399 1.8E-106 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_00840 82f546d8207ea756fe368f8e16e54421 399 Pfam PF02803 Thiolase, C-terminal domain 277 398 1.5E-33 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UA74_00840 82f546d8207ea756fe368f8e16e54421 399 SUPERFAMILY SSF53901 4 275 5.01E-62 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_00840 82f546d8207ea756fe368f8e16e54421 399 Gene3D G3DSA:3.40.47.10 6 282 1.4E-124 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_00840 82f546d8207ea756fe368f8e16e54421 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 1.2E-113 T 12-10-2018 IPR002155 Thiolase GO:0016747 UA74_00840 82f546d8207ea756fe368f8e16e54421 399 Gene3D G3DSA:3.40.47.10 146 396 1.4E-124 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_00840 82f546d8207ea756fe368f8e16e54421 399 SUPERFAMILY SSF53901 278 398 9.75E-32 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_00840 82f546d8207ea756fe368f8e16e54421 399 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 UA74_21085 d4341a8a4321e5177b77c837182d639f 423 Pfam PF13416 Bacterial extracellular solute-binding protein 48 351 2.6E-28 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_21085 d4341a8a4321e5177b77c837182d639f 423 SUPERFAMILY SSF53850 23 420 5.69E-41 T 12-10-2018 UA74_21085 d4341a8a4321e5177b77c837182d639f 423 Gene3D G3DSA:3.40.190.10 50 350 3.0E-53 T 12-10-2018 UA74_21085 d4341a8a4321e5177b77c837182d639f 423 Gene3D G3DSA:3.40.190.10 146 411 3.0E-53 T 12-10-2018 UA74_24450 fcdc93cce98306a67963b51d81424a4d 292 SUPERFAMILY SSF52540 4 219 2.67E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24450 fcdc93cce98306a67963b51d81424a4d 292 SMART SM00382 29 206 2.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_24450 fcdc93cce98306a67963b51d81424a4d 292 Pfam PF00005 ABC transporter 21 154 1.1E-14 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_24450 fcdc93cce98306a67963b51d81424a4d 292 Gene3D G3DSA:3.40.50.300 2 225 1.1E-34 T 12-10-2018 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 Pfam PF00067 Cytochrome P450 203 365 7.1E-17 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 PRINTS PR00359 B-class P450 signature 151 166 9.1E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 PRINTS PR00359 B-class P450 signature 134 150 9.1E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 PRINTS PR00359 B-class P450 signature 87 98 9.1E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 PRINTS PR00359 B-class P450 signature 268 279 9.1E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 PRINTS PR00359 B-class P450 signature 187 209 9.1E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 PRINTS PR00359 B-class P450 signature 344 355 9.1E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 PRINTS PR00359 B-class P450 signature 314 329 9.1E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 PRINTS PR00359 B-class P450 signature 286 313 9.1E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 PRINTS PR00359 B-class P450 signature 335 344 9.1E-50 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 SUPERFAMILY SSF48264 14 395 4.06E-77 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_22975 8e6ff5a968f7ba5ab12352021cbf29be 395 Gene3D G3DSA:1.10.630.10 8 395 6.0E-106 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_23715 8e6488800a301197c9fc1bc2c96a99aa 489 Gene3D G3DSA:3.50.50.60 11 465 6.4E-115 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_23715 8e6488800a301197c9fc1bc2c96a99aa 489 Pfam PF01593 Flavin containing amine oxidoreductase 17 473 2.1E-40 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UA74_23715 8e6488800a301197c9fc1bc2c96a99aa 489 Gene3D G3DSA:3.90.660.20 43 424 6.4E-115 T 12-10-2018 UA74_23715 8e6488800a301197c9fc1bc2c96a99aa 489 SUPERFAMILY SSF54373 310 425 1.31E-20 T 12-10-2018 UA74_23715 8e6488800a301197c9fc1bc2c96a99aa 489 Gene3D G3DSA:1.10.3110.10 110 203 6.4E-115 T 12-10-2018 UA74_23715 8e6488800a301197c9fc1bc2c96a99aa 489 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 9 473 9.2E-50 T 12-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 UA74_23715 8e6488800a301197c9fc1bc2c96a99aa 489 SUPERFAMILY SSF51905 8 474 5.44E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_08270 ec35aef12b28d97369a54562d8fad0e3 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 277 8.6E-88 T 12-10-2018 IPR003797 DegV UA74_08270 ec35aef12b28d97369a54562d8fad0e3 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 3.0E-83 T 12-10-2018 IPR003797 DegV UA74_08270 ec35aef12b28d97369a54562d8fad0e3 286 SUPERFAMILY SSF82549 2 279 7.85E-78 T 12-10-2018 UA74_08270 ec35aef12b28d97369a54562d8fad0e3 286 Gene3D G3DSA:3.40.50.10170 1 151 8.0E-44 T 12-10-2018 UA74_08270 ec35aef12b28d97369a54562d8fad0e3 286 Gene3D G3DSA:3.30.1180.10 153 278 2.3E-40 T 12-10-2018 UA74_10405 a3bf86af07d68a53a72efa8195a26d7a 541 Gene3D G3DSA:3.90.870.20 336 539 3.5E-73 T 12-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily UA74_10405 a3bf86af07d68a53a72efa8195a26d7a 541 Pfam PF02543 Carbamoyltransferase N-terminus 2 322 1.6E-55 T 12-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 UA74_10405 a3bf86af07d68a53a72efa8195a26d7a 541 SUPERFAMILY SSF53067 1 325 7.77E-18 T 12-10-2018 UA74_10405 a3bf86af07d68a53a72efa8195a26d7a 541 Gene3D G3DSA:3.30.420.40 10 322 7.1E-91 T 12-10-2018 UA74_10405 a3bf86af07d68a53a72efa8195a26d7a 541 Gene3D G3DSA:3.30.420.350 122 315 7.1E-91 T 12-10-2018 UA74_10405 a3bf86af07d68a53a72efa8195a26d7a 541 Pfam PF16861 Carbamoyltransferase C-terminus 371 540 7.5E-63 T 12-10-2018 IPR031730 Carbamoyltransferase, C-terminal UA74_10405 a3bf86af07d68a53a72efa8195a26d7a 541 SUPERFAMILY SSF55821 363 538 8.85E-6 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily UA74_29445 f6ef99f59c253c9b9bc7d19737c1b4b1 364 Pfam PF13515 Fusaric acid resistance protein-like 32 154 3.8E-14 T 12-10-2018 UA74_09515 88f69c1a460d7398d321f85a4ad6ee25 169 Pfam PF09056 Prokaryotic phospholipase A2 42 147 1.8E-40 T 12-10-2018 IPR015141 Phospholipase A2, prokaryotic/fungal UA74_09515 88f69c1a460d7398d321f85a4ad6ee25 169 Gene3D G3DSA:1.20.90.10 36 148 9.7E-41 T 12-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 UA74_09515 88f69c1a460d7398d321f85a4ad6ee25 169 SUPERFAMILY SSF48619 38 147 4.03E-35 T 12-10-2018 IPR036444 Phospholipase A2 domain superfamily GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 UA74_07235 98c89ed74359ff633c9d3e3ebc38978a 336 Pfam PF14561 Tetratricopeptide repeat 258 336 4.7E-18 T 12-10-2018 UA74_07235 98c89ed74359ff633c9d3e3ebc38978a 336 ProSitePatterns PS00194 Thioredoxin family active site. 90 108 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UA74_07235 98c89ed74359ff633c9d3e3ebc38978a 336 Gene3D G3DSA:1.25.40.10 255 336 2.5E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_07235 98c89ed74359ff633c9d3e3ebc38978a 336 Gene3D G3DSA:3.40.30.10 67 178 1.2E-30 T 12-10-2018 UA74_07235 98c89ed74359ff633c9d3e3ebc38978a 336 Gene3D G3DSA:1.25.40.10 201 249 6.4E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_07235 98c89ed74359ff633c9d3e3ebc38978a 336 SUPERFAMILY SSF52833 64 175 6.26E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_07235 98c89ed74359ff633c9d3e3ebc38978a 336 Pfam PF00085 Thioredoxin 68 171 1.3E-24 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 UA74_04315 9655fc183898d715e2ff971e2b1f0153 537 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 452 4.4E-73 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UA74_04315 9655fc183898d715e2ff971e2b1f0153 537 Gene3D G3DSA:1.20.1250.20 288 529 6.4E-8 T 12-10-2018 UA74_04315 9655fc183898d715e2ff971e2b1f0153 537 SUPERFAMILY SSF103473 5 526 1.06E-55 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_04315 9655fc183898d715e2ff971e2b1f0153 537 Gene3D G3DSA:1.20.1720.10 14 271 1.1E-43 T 12-10-2018 UA74_04315 9655fc183898d715e2ff971e2b1f0153 537 Pfam PF07690 Major Facilitator Superfamily 18 427 2.7E-41 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_15305 c93b9e0ceda83dfafbc22e5db39c6a07 196 SUPERFAMILY SSF46689 2 68 4.99E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_15305 c93b9e0ceda83dfafbc22e5db39c6a07 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 4.8E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15305 c93b9e0ceda83dfafbc22e5db39c6a07 196 Gene3D G3DSA:1.10.357.10 5 193 1.2E-52 T 12-10-2018 UA74_25800 43bb9971b9881024335cca13dd388c38 165 Pfam PF05995 Cysteine dioxygenase type I 27 150 1.7E-23 T 12-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 UA74_25800 43bb9971b9881024335cca13dd388c38 165 SUPERFAMILY SSF51182 25 152 1.1E-29 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_25800 43bb9971b9881024335cca13dd388c38 165 Gene3D G3DSA:2.60.120.10 8 155 6.0E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 9.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 9.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 9.5E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 183 0.004 T 12-10-2018 UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 SUPERFAMILY SSF51735 3 241 1.57E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 Gene3D G3DSA:3.40.50.720 1 241 1.5E-60 T 12-10-2018 UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 7.3E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 7.3E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 7.3E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.3E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 7.3E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 7.3E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_25625 1e2b78929b6f38ecc525cce38040cfc5 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 238 4.7E-41 T 12-10-2018 UA74_20410 2b9a7ceb3493fc4918bcad22e5576c04 140 SUPERFAMILY SSF46689 9 60 4.44E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_20410 2b9a7ceb3493fc4918bcad22e5576c04 140 Pfam PF12833 Helix-turn-helix domain 32 111 2.8E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_20410 2b9a7ceb3493fc4918bcad22e5576c04 140 Gene3D G3DSA:1.10.10.60 5 113 4.2E-30 T 12-10-2018 UA74_20410 2b9a7ceb3493fc4918bcad22e5576c04 140 SMART SM00342 26 109 4.3E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_20410 2b9a7ceb3493fc4918bcad22e5576c04 140 SUPERFAMILY SSF46689 62 115 1.08E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_20410 2b9a7ceb3493fc4918bcad22e5576c04 140 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 63 105 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UA74_20410 2b9a7ceb3493fc4918bcad22e5576c04 140 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 78 93 3.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_20410 2b9a7ceb3493fc4918bcad22e5576c04 140 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 93 109 3.1E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UA74_23600 29d12633e7873715b0f0814a51831a04 271 Gene3D G3DSA:1.20.120.1630 62 262 7.0E-9 T 12-10-2018 UA74_23600 29d12633e7873715b0f0814a51831a04 271 Pfam PF06966 Protein of unknown function (DUF1295) 27 256 4.4E-66 T 12-10-2018 IPR010721 Protein of unknown function DUF1295 UA74_19435 ba66d006701231754fdd67b37bee3709 1222 Pfam PF05762 VWA domain containing CoxE-like protein 995 1216 5.7E-57 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like UA74_19435 ba66d006701231754fdd67b37bee3709 1222 SUPERFAMILY SSF53300 1056 1207 3.77E-20 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_19435 ba66d006701231754fdd67b37bee3709 1222 Gene3D G3DSA:3.40.50.410 1054 1201 2.0E-7 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_18495 1b90577d1a035d0c5c9732724dc9a302 422 Pfam PF10544 T5orf172 domain 301 388 2.3E-12 T 12-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding UA74_18495 1b90577d1a035d0c5c9732724dc9a302 422 Pfam PF13250 Domain of unknown function (DUF4041) 151 206 4.3E-16 T 12-10-2018 IPR025280 Domain of unknown function DUF4041 UA74_18495 1b90577d1a035d0c5c9732724dc9a302 422 SMART SM00974 311 394 9.5E-26 T 12-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding UA74_02060 a5e31700bbf79f3efa0fd125c2130a42 284 Pfam PF13560 Helix-turn-helix domain 16 76 9.5E-12 T 12-10-2018 UA74_02060 a5e31700bbf79f3efa0fd125c2130a42 284 SUPERFAMILY SSF47413 14 73 2.28E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_02060 a5e31700bbf79f3efa0fd125c2130a42 284 Gene3D G3DSA:1.10.260.40 12 75 5.0E-10 T 12-10-2018 UA74_02060 a5e31700bbf79f3efa0fd125c2130a42 284 SMART SM00530 19 74 3.3E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_29910 77248e0640a80974f5ab9e62b28f8734 473 Pfam PF01546 Peptidase family M20/M25/M40 95 465 2.6E-21 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 UA74_29910 77248e0640a80974f5ab9e62b28f8734 473 Gene3D G3DSA:3.40.630.10 374 472 3.3E-7 T 12-10-2018 UA74_29910 77248e0640a80974f5ab9e62b28f8734 473 SUPERFAMILY SSF53187 14 467 1.17E-43 T 12-10-2018 UA74_29910 77248e0640a80974f5ab9e62b28f8734 473 Pfam PF07687 Peptidase dimerisation domain 207 366 5.2E-10 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain UA74_29910 77248e0640a80974f5ab9e62b28f8734 473 Gene3D G3DSA:3.40.630.10 10 212 2.6E-28 T 12-10-2018 UA74_19975 e78db31f4cdbc81dbd62713a52ec346e 162 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 7 151 1.2E-31 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_19975 e78db31f4cdbc81dbd62713a52ec346e 162 Pfam PF02502 Ribose/Galactose Isomerase 7 145 9.6E-44 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_19975 e78db31f4cdbc81dbd62713a52ec346e 162 SUPERFAMILY SSF89623 4 151 2.22E-46 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_19975 e78db31f4cdbc81dbd62713a52ec346e 162 PIRSF PIRSF005384 5 153 6.5E-44 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_19975 e78db31f4cdbc81dbd62713a52ec346e 162 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 5 151 6.6E-63 T 12-10-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 UA74_19975 e78db31f4cdbc81dbd62713a52ec346e 162 Gene3D G3DSA:3.40.1400.10 3 154 8.8E-46 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_27585 94a55e0a3ca9e320fd948e8f87921aea 210 SUPERFAMILY SSF55729 15 163 3.54E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_27585 94a55e0a3ca9e320fd948e8f87921aea 210 Pfam PF13673 Acetyltransferase (GNAT) domain 55 163 1.8E-9 T 12-10-2018 IPR000182 GNAT domain UA74_27585 94a55e0a3ca9e320fd948e8f87921aea 210 Gene3D G3DSA:3.40.630.30 2 155 2.3E-20 T 12-10-2018 UA74_15415 26116a265284885065f784743273e55c 272 Gene3D G3DSA:3.40.50.1820 2 265 3.2E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15415 26116a265284885065f784743273e55c 272 SUPERFAMILY SSF53474 4 264 7.71E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15415 26116a265284885065f784743273e55c 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 1.9E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15415 26116a265284885065f784743273e55c 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.9E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15415 26116a265284885065f784743273e55c 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.9E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15415 26116a265284885065f784743273e55c 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.9E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15415 26116a265284885065f784743273e55c 272 Pfam PF12697 Alpha/beta hydrolase family 28 258 8.1E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_15415 26116a265284885065f784743273e55c 272 PRINTS PR00412 Epoxide hydrolase signature 94 107 5.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15415 26116a265284885065f784743273e55c 272 PRINTS PR00412 Epoxide hydrolase signature 240 262 5.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_15415 26116a265284885065f784743273e55c 272 PRINTS PR00412 Epoxide hydrolase signature 51 66 5.2E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_20030 21072064e683e949da441cfaff99a9c1 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 308 7.3E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_20030 21072064e683e949da441cfaff99a9c1 315 SUPERFAMILY SSF161098 33 315 4.06E-69 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20030 21072064e683e949da441cfaff99a9c1 315 Gene3D G3DSA:1.10.3720.10 29 302 2.6E-63 T 12-10-2018 IPR035906 MetI-like superfamily UA74_19800 1d46dc980e3d0a7d35266f1901d0eb18 320 SUPERFAMILY SSF56059 131 316 2.43E-12 T 12-10-2018 UA74_19800 1d46dc980e3d0a7d35266f1901d0eb18 320 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 314 4.8E-112 T 12-10-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV-5884 family UA74_19800 1d46dc980e3d0a7d35266f1901d0eb18 320 Gene3D G3DSA:3.30.470.20 208 316 2.0E-12 T 12-10-2018 UA74_28505 d66a268f01c1854403a9346cba0f93f5 396 Gene3D G3DSA:3.60.21.10 130 315 2.8E-12 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_28505 d66a268f01c1854403a9346cba0f93f5 396 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 66 311 1.9E-64 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA UA74_28505 d66a268f01c1854403a9346cba0f93f5 396 SMART SM00854 65 313 3.2E-79 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA UA74_28505 d66a268f01c1854403a9346cba0f93f5 396 SUPERFAMILY SSF56300 65 353 1.25E-36 T 12-10-2018 UA74_24975 13f2b60963f072110d4a824280af5b27 208 Pfam PF12079 Protein of unknown function (DUF3558) 17 199 2.9E-22 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_08035 d0a229b4f6835aeb5f2167b53f79e4fe 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 7.6E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_08035 d0a229b4f6835aeb5f2167b53f79e4fe 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_08035 d0a229b4f6835aeb5f2167b53f79e4fe 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_08035 d0a229b4f6835aeb5f2167b53f79e4fe 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_08035 d0a229b4f6835aeb5f2167b53f79e4fe 207 SUPERFAMILY SSF48498 83 180 3.18E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_08035 d0a229b4f6835aeb5f2167b53f79e4fe 207 SUPERFAMILY SSF46689 8 84 6.98E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_08035 d0a229b4f6835aeb5f2167b53f79e4fe 207 Gene3D G3DSA:1.10.357.10 6 192 2.2E-28 T 12-10-2018 UA74_08035 d0a229b4f6835aeb5f2167b53f79e4fe 207 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 84 177 2.0E-6 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal UA74_17355 731e092651bdcf54b7fb8814c4c28c16 301 SUPERFAMILY SSF53474 38 280 8.26E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17355 731e092651bdcf54b7fb8814c4c28c16 301 Gene3D G3DSA:3.40.50.1820 60 280 7.5E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17355 731e092651bdcf54b7fb8814c4c28c16 301 Pfam PF12697 Alpha/beta hydrolase family 75 262 4.5E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_02275 7c6db44532cf296c36858fa426e77f9f 350 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 187 1.0E-21 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_02275 7c6db44532cf296c36858fa426e77f9f 350 SUPERFAMILY SSF51735 1 316 2.55E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_02275 7c6db44532cf296c36858fa426e77f9f 350 Gene3D G3DSA:3.40.50.720 1 320 1.7E-41 T 12-10-2018 UA74_18410 9fa9fa88847ed70c911f8fc491937ddf 221 Pfam PF00156 Phosphoribosyl transferase domain 13 199 4.2E-23 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UA74_18410 9fa9fa88847ed70c911f8fc491937ddf 221 Gene3D G3DSA:3.40.50.2020 8 208 1.2E-66 T 12-10-2018 UA74_18410 9fa9fa88847ed70c911f8fc491937ddf 221 SUPERFAMILY SSF53271 7 211 1.79E-43 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like UA74_18410 9fa9fa88847ed70c911f8fc491937ddf 221 Gene3D G3DSA:3.30.1310.20 58 120 1.2E-66 T 12-10-2018 UA74_26130 59f9830151ff2662bae73f8c0cd568bd 262 Pfam PF00561 alpha/beta hydrolase fold 16 136 4.1E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_26130 59f9830151ff2662bae73f8c0cd568bd 262 SUPERFAMILY SSF53474 8 250 1.08E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26130 59f9830151ff2662bae73f8c0cd568bd 262 Gene3D G3DSA:3.40.50.1820 3 251 6.8E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23740 c75c5ddcaededc34215161dd07976d05 82 Pfam PF13396 Phospholipase_D-nuclease N-terminal 17 57 2.2E-5 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal UA74_11655 5a31a11cf5e7b4e7423ba16095cd7937 326 Gene3D G3DSA:3.40.190.10 80 311 5.3E-72 T 12-10-2018 UA74_11655 5a31a11cf5e7b4e7423ba16095cd7937 326 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 92 311 1.0E-45 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_11655 5a31a11cf5e7b4e7423ba16095cd7937 326 Gene3D G3DSA:3.40.190.10 182 270 5.3E-72 T 12-10-2018 UA74_11655 5a31a11cf5e7b4e7423ba16095cd7937 326 SUPERFAMILY SSF53850 81 311 2.63E-51 T 12-10-2018 UA74_11655 5a31a11cf5e7b4e7423ba16095cd7937 326 SMART SM00062 91 313 2.3E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_16805 84157c665f7f4973cd5b48aca81cc6d9 280 Pfam PF07920 Protein of unknown function (DUF1684) 136 273 9.7E-24 T 12-10-2018 IPR012467 Protein of unknown function DUF1684 UA74_06900 6cd23f66f0aa38a3e037a4c67c597bc7 317 ProSitePatterns PS01218 TatC family signature. 192 211 - T 12-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site UA74_06900 6cd23f66f0aa38a3e037a4c67c597bc7 317 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 33 265 9.1E-57 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_06900 6cd23f66f0aa38a3e037a4c67c597bc7 317 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 142 168 3.2E-37 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_06900 6cd23f66f0aa38a3e037a4c67c597bc7 317 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 124 142 3.2E-37 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_06900 6cd23f66f0aa38a3e037a4c67c597bc7 317 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 192 220 3.2E-37 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_06900 6cd23f66f0aa38a3e037a4c67c597bc7 317 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 32 59 3.2E-37 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_06900 6cd23f66f0aa38a3e037a4c67c597bc7 317 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 24 277 14.721 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_06900 6cd23f66f0aa38a3e037a4c67c597bc7 317 Pfam PF00902 Sec-independent protein translocase protein (TatC) 35 258 6.3E-53 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 100 1.1E-11 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SMART SM01043 107 248 2.3E-39 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SUPERFAMILY SSF48452 713 826 1.02E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Gene3D G3DSA:1.25.40.10 827 1001 6.2E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Gene3D G3DSA:1.25.40.10 586 826 3.2E-27 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Pfam PF13424 Tetratricopeptide repeat 713 785 3.5E-9 T 12-10-2018 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Pfam PF13424 Tetratricopeptide repeat 912 984 4.5E-12 T 12-10-2018 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Pfam PF13424 Tetratricopeptide repeat 794 865 8.9E-11 T 12-10-2018 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SUPERFAMILY SSF52540 271 531 3.62E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SMART SM00028 953 986 2.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SMART SM00028 754 787 4.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SMART SM00028 913 946 0.57 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SMART SM00028 794 827 9.8E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SMART SM00028 874 907 0.012 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SMART SM00028 834 867 39.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SMART SM00028 714 747 50.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Gene3D G3DSA:1.10.10.10 7 102 1.2E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Pfam PF13374 Tetratricopeptide repeat 877 903 2.3E-4 T 12-10-2018 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Gene3D G3DSA:3.40.50.300 266 417 1.6E-25 T 12-10-2018 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SMART SM00862 25 100 6.2E-17 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SUPERFAMILY SSF48452 105 263 6.83E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Pfam PF00931 NB-ARC domain 283 474 2.6E-9 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Pfam PF03704 Bacterial transcriptional activator domain 107 248 2.0E-31 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SUPERFAMILY SSF48452 795 985 2.43E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 SUPERFAMILY SSF46894 21 100 2.27E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 PRINTS PR00364 Disease resistance protein signature 376 390 3.4E-6 T 12-10-2018 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 PRINTS PR00364 Disease resistance protein signature 298 313 3.4E-6 T 12-10-2018 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 PRINTS PR00364 Disease resistance protein signature 464 478 3.4E-6 T 12-10-2018 UA74_13185 dab6ef586d2e133f9261c772251d0a93 1008 Gene3D G3DSA:1.25.40.10 105 265 4.6E-37 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_05715 c1acbbc6886dafe181f2dc3f30b3bac3 100 Pfam PF00550 Phosphopantetheine attachment site 19 86 1.9E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_05715 c1acbbc6886dafe181f2dc3f30b3bac3 100 SUPERFAMILY SSF47336 18 90 2.62E-13 T 12-10-2018 IPR036736 ACP-like superfamily UA74_05715 c1acbbc6886dafe181f2dc3f30b3bac3 100 Gene3D G3DSA:1.10.1200.10 15 98 4.8E-19 T 12-10-2018 IPR036736 ACP-like superfamily UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 Pfam PF02875 Mur ligase family, glutamate ligase domain 345 432 4.0E-20 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 Gene3D G3DSA:3.90.190.20 342 497 1.4E-33 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 Pfam PF01225 Mur ligase family, catalytic domain 30 74 6.3E-8 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 Gene3D G3DSA:3.40.1390.10 1 81 1.0E-23 T 12-10-2018 UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 SUPERFAMILY SSF63418 2 80 3.27E-18 T 12-10-2018 IPR035911 MurE/MurF, N-terminal UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 487 1.4E-117 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 SUPERFAMILY SSF53244 345 487 1.23E-31 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 Gene3D G3DSA:3.40.1190.10 107 339 3.2E-68 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 Pfam PF08245 Mur ligase middle domain 132 322 4.1E-40 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 489 30.771 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UA74_09625 b9b5179064ef290c404dc4befd3e4270 500 SUPERFAMILY SSF53623 127 338 7.98E-51 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UA74_29240 81f5a8e8294fca004d96911347994cc1 276 Pfam PF04672 S-adenosyl methyltransferase 8 256 3.7E-78 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_29240 81f5a8e8294fca004d96911347994cc1 276 SUPERFAMILY SSF53335 17 243 1.34E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_29240 81f5a8e8294fca004d96911347994cc1 276 PIRSF PIRSF017393 2 275 1.5E-84 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_29240 81f5a8e8294fca004d96911347994cc1 276 Gene3D G3DSA:3.40.50.150 2 276 9.3E-92 T 12-10-2018 UA74_17520 706b2c5a8f02c57f68e0494259ffb301 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 532 6.3E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_17520 706b2c5a8f02c57f68e0494259ffb301 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_17520 706b2c5a8f02c57f68e0494259ffb301 550 Pfam PF00501 AMP-binding enzyme 33 447 6.5E-82 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_17520 706b2c5a8f02c57f68e0494259ffb301 550 Gene3D G3DSA:3.30.300.310 443 545 3.1E-24 T 12-10-2018 UA74_17520 706b2c5a8f02c57f68e0494259ffb301 550 Gene3D G3DSA:2.30.38.10 366 441 4.4E-26 T 12-10-2018 UA74_17520 706b2c5a8f02c57f68e0494259ffb301 550 SUPERFAMILY SSF56801 12 543 3.92E-132 T 12-10-2018 UA74_17520 706b2c5a8f02c57f68e0494259ffb301 550 Gene3D G3DSA:3.40.50.980 192 365 3.2E-54 T 12-10-2018 UA74_17520 706b2c5a8f02c57f68e0494259ffb301 550 Gene3D G3DSA:3.40.50.980 23 180 3.0E-42 T 12-10-2018 UA74_10110 c0813cdb4d758f60444fd779586ed705 182 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 113 128 3.0E-14 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_10110 c0813cdb4d758f60444fd779586ed705 182 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 145 161 3.0E-14 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_10110 c0813cdb4d758f60444fd779586ed705 182 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 67 75 3.0E-14 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_10110 c0813cdb4d758f60444fd779586ed705 182 ProSitePatterns PS00855 Signal peptidases II signature. 116 128 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_10110 c0813cdb4d758f60444fd779586ed705 182 Pfam PF01252 Signal peptidase (SPase) II 33 164 1.6E-27 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_10110 c0813cdb4d758f60444fd779586ed705 182 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 24 170 12.653 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_10110 c0813cdb4d758f60444fd779586ed705 182 TIGRFAM TIGR00077 lspA: signal peptidase II 28 167 2.9E-23 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UA74_04755 a504041dc4c90e6af98b3fb04a83c44f 262 Gene3D G3DSA:3.40.50.150 2 262 9.0E-94 T 12-10-2018 UA74_04755 a504041dc4c90e6af98b3fb04a83c44f 262 Pfam PF04672 S-adenosyl methyltransferase 10 261 2.2E-79 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_04755 a504041dc4c90e6af98b3fb04a83c44f 262 SUPERFAMILY SSF53335 7 242 3.07E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_04755 a504041dc4c90e6af98b3fb04a83c44f 262 PIRSF PIRSF017393 2 262 4.4E-83 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_22515 efe533971900e5c56d2cdc53336c117a 130 SUPERFAMILY SSF46785 11 119 8.77E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22515 efe533971900e5c56d2cdc53336c117a 130 Pfam PF01638 HxlR-like helix-turn-helix 23 109 6.1E-24 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_22515 efe533971900e5c56d2cdc53336c117a 130 Gene3D G3DSA:1.10.10.10 3 123 1.6E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 Pfam PF13229 Right handed beta helix region 84 238 9.9E-17 T 12-10-2018 IPR039448 Right handed beta helix domain UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 SUPERFAMILY SSF51126 3 333 6.91E-39 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 185 206 1000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 163 184 230.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 115 137 7800.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 258 287 8900.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 138 160 170.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 92 114 10.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 SMART SM00710 217 240 540.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_05775 4288718f67c82761bf83a516c72ee6d7 347 Gene3D G3DSA:2.160.20.10 15 341 4.4E-36 T 12-10-2018 IPR012334 Pectin lyase fold UA74_24125 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24125 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24125 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24125 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24125 78e9331fc722487d5a72ccd7bee734a7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_24125 78e9331fc722487d5a72ccd7bee734a7 250 Gene3D G3DSA:3.40.50.720 2 249 1.8E-48 T 12-10-2018 UA74_24125 78e9331fc722487d5a72ccd7bee734a7 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 246 9.3E-38 T 12-10-2018 UA74_24125 78e9331fc722487d5a72ccd7bee734a7 250 SUPERFAMILY SSF51735 2 248 6.82E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_19340 d63ecc89ed1f7715e00cbca0e602a12f 390 Pfam PF00756 Putative esterase 119 355 5.7E-27 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 UA74_19340 d63ecc89ed1f7715e00cbca0e602a12f 390 Gene3D G3DSA:3.40.50.1820 88 387 9.1E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19340 d63ecc89ed1f7715e00cbca0e602a12f 390 SUPERFAMILY SSF53474 114 364 1.73E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 120 134 3.6E-46 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 136 149 3.6E-46 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 93 114 3.6E-46 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 335 361 3.6E-46 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 290 309 3.6E-46 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 183 3.6E-46 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 210 229 3.6E-46 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 93 3.6E-46 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 Gene3D G3DSA:3.40.190.10 176 386 5.2E-109 T 12-10-2018 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 SUPERFAMILY SSF53850 71 390 6.79E-87 T 12-10-2018 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 PIRSF PIRSF019574 29 390 5.9E-105 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 Pfam PF13416 Bacterial extracellular solute-binding protein 91 355 4.9E-35 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_08990 d66d18cf90acb0c83aea260d73f9d405 390 Gene3D G3DSA:3.40.190.10 75 357 5.2E-109 T 12-10-2018 UA74_17885 4e23831a8f952f354a3315cb1b934e77 250 SUPERFAMILY SSF46689 25 88 1.3E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_17885 4e23831a8f952f354a3315cb1b934e77 250 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 81 2.9E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_17885 4e23831a8f952f354a3315cb1b934e77 250 Gene3D G3DSA:1.10.357.10 92 250 6.9E-34 T 12-10-2018 UA74_17885 4e23831a8f952f354a3315cb1b934e77 250 Gene3D G3DSA:1.10.10.60 10 87 3.3E-24 T 12-10-2018 UA74_17885 4e23831a8f952f354a3315cb1b934e77 250 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 97 238 4.1E-17 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UA74_17885 4e23831a8f952f354a3315cb1b934e77 250 SUPERFAMILY SSF48498 100 241 8.56E-19 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_26650 450d3a5e2fa3521b58f4495e2ae15677 219 Gene3D G3DSA:2.160.20.100 18 217 9.3E-20 T 12-10-2018 UA74_26650 450d3a5e2fa3521b58f4495e2ae15677 219 SUPERFAMILY SSF141571 52 208 9.94E-17 T 12-10-2018 UA74_14420 050db412583a17b6e48d2c84528f30a7 298 SUPERFAMILY SSF52540 33 259 3.18E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14420 050db412583a17b6e48d2c84528f30a7 298 SMART SM00382 58 246 3.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_14420 050db412583a17b6e48d2c84528f30a7 298 Gene3D G3DSA:3.40.50.300 33 285 1.2E-65 T 12-10-2018 UA74_14420 050db412583a17b6e48d2c84528f30a7 298 Pfam PF00005 ABC transporter 50 197 1.3E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_14420 050db412583a17b6e48d2c84528f30a7 298 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_26565 cc3100bbd0abeb9adae6532fd4580913 505 Gene3D G3DSA:1.20.1740.10 24 495 1.7E-114 T 12-10-2018 UA74_26565 cc3100bbd0abeb9adae6532fd4580913 505 Pfam PF13520 Amino acid permease 32 458 5.2E-49 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UA74_26565 cc3100bbd0abeb9adae6532fd4580913 505 PIRSF PIRSF006060 6 500 6.2E-87 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UA74_26640 dc2d4c45ff375d482d51b61a0a9546fb 385 SUPERFAMILY SSF102114 21 340 1.2E-27 T 12-10-2018 UA74_26640 dc2d4c45ff375d482d51b61a0a9546fb 385 Pfam PF04055 Radical SAM superfamily 34 188 2.2E-10 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_26640 dc2d4c45ff375d482d51b61a0a9546fb 385 Gene3D G3DSA:3.20.20.70 23 376 2.0E-59 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_28095 3d97c8d53670e28a2461f8564b23b7ad 401 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 8 399 9.5E-54 T 12-10-2018 IPR021368 Type VII secretion system protein EccE UA74_28095 3d97c8d53670e28a2461f8564b23b7ad 401 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 207 309 9.4E-21 T 12-10-2018 IPR021368 Type VII secretion system protein EccE UA74_27975 7bf2e61c73a0599cbdd11e56f384a455 367 SUPERFAMILY SSF53474 59 347 4.29E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_27975 7bf2e61c73a0599cbdd11e56f384a455 367 Pfam PF12697 Alpha/beta hydrolase family 84 343 1.9E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_27975 7bf2e61c73a0599cbdd11e56f384a455 367 Gene3D G3DSA:3.40.50.1820 51 356 7.5E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22160 8c44668b919c48f27b431d6101b7a405 396 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 142 212 4.1E-8 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UA74_22160 8c44668b919c48f27b431d6101b7a405 396 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 129 1.2E-20 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_22160 8c44668b919c48f27b431d6101b7a405 396 Gene3D G3DSA:3.40.50.720 8 138 1.8E-30 T 12-10-2018 UA74_22160 8c44668b919c48f27b431d6101b7a405 396 SUPERFAMILY SSF51735 5 160 9.86E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22160 8c44668b919c48f27b431d6101b7a405 396 Gene3D G3DSA:3.30.360.10 139 380 7.7E-36 T 12-10-2018 UA74_22160 8c44668b919c48f27b431d6101b7a405 396 SUPERFAMILY SSF55347 135 321 4.41E-25 T 12-10-2018 UA74_03415 1a351aedd88322aeff9444df87cc4a88 537 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 345 536 8.9E-19 T 12-10-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-7921|MetaCyc: PWY-7922|MetaCyc: PWY-7979|Reactome: R-HSA-5173105 UA74_03415 1a351aedd88322aeff9444df87cc4a88 537 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 133 309 1.7E-7 T 12-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 UA74_17345 cb78199f57d4d38f3bdde4cfcd8d402d 142 Gene3D G3DSA:2.30.110.10 3 140 6.8E-52 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_17345 cb78199f57d4d38f3bdde4cfcd8d402d 142 Pfam PF04075 F420H(2)-dependent quinone reductase 16 135 1.3E-34 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_17345 cb78199f57d4d38f3bdde4cfcd8d402d 142 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 27 137 1.9E-30 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_26670 08e9ec88778c8a5d611ced755fc7d7d3 834 Pfam PF00535 Glycosyl transferase family 2 11 124 1.0E-16 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_26670 08e9ec88778c8a5d611ced755fc7d7d3 834 Gene3D G3DSA:3.90.550.10 2 234 2.3E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_26670 08e9ec88778c8a5d611ced755fc7d7d3 834 Gene3D G3DSA:3.40.50.2000 568 755 4.0E-23 T 12-10-2018 UA74_26670 08e9ec88778c8a5d611ced755fc7d7d3 834 Pfam PF13692 Glycosyl transferases group 1 581 737 2.4E-10 T 12-10-2018 UA74_26670 08e9ec88778c8a5d611ced755fc7d7d3 834 SUPERFAMILY SSF53448 7 250 1.5E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_26670 08e9ec88778c8a5d611ced755fc7d7d3 834 SUPERFAMILY SSF53756 378 768 1.51E-23 T 12-10-2018 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 SUPERFAMILY SSF55174 334 427 1.38E-15 T 12-10-2018 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 Gene3D G3DSA:1.10.240.10 230 334 5.9E-35 T 12-10-2018 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 Pfam PF00579 tRNA synthetases class I (W and Y) 37 331 5.8E-79 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 Gene3D G3DSA:3.40.50.620 7 229 6.0E-81 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 57 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 Gene3D G3DSA:3.10.290.10 335 429 1.1E-27 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 9 428 42.328 T 12-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 SUPERFAMILY SSF52374 10 331 1.35E-91 T 12-10-2018 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 223 235 2.4E-28 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 169 184 2.4E-28 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 190 212 2.4E-28 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 51 73 2.4E-28 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_21590 b8dffdd77be2b2aa5b8a707c1a3f6058 430 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 10 426 2.5E-102 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UA74_04025 2765d612c80cc6a51f70cbd4322edd57 293 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 153 7.0E-27 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_04025 2765d612c80cc6a51f70cbd4322edd57 293 SUPERFAMILY SSF102588 4 287 1.96E-75 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_04025 2765d612c80cc6a51f70cbd4322edd57 293 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 288 54.026 T 12-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 UA74_04025 2765d612c80cc6a51f70cbd4322edd57 293 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 287 8.1E-155 T 12-10-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 UA74_04025 2765d612c80cc6a51f70cbd4322edd57 293 Gene3D G3DSA:3.40.50.10320 1 292 5.0E-81 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_04435 4e2f94c88e5e74f70e55ba3892bbc444 178 Gene3D G3DSA:3.30.2030.20 29 176 2.5E-8 T 12-10-2018 UA74_04435 4e2f94c88e5e74f70e55ba3892bbc444 178 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 31 173 1.3E-36 T 12-10-2018 IPR032018 Putative lipoprotein, pathogenic bacteria UA74_05310 ee02377490fda364e077cf15c8ef74bc 346 SUPERFAMILY SSF53335 136 294 1.24E-13 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_05630 96647c48adeabf59d50eb57baeb3a0c9 303 SUPERFAMILY SSF51735 98 281 9.11E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_05630 96647c48adeabf59d50eb57baeb3a0c9 303 SUPERFAMILY SSF52283 5 120 1.7E-23 T 12-10-2018 UA74_05630 96647c48adeabf59d50eb57baeb3a0c9 303 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 302 6.5E-24 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UA74_05630 96647c48adeabf59d50eb57baeb3a0c9 303 Gene3D G3DSA:3.40.50.720 9 302 2.6E-92 T 12-10-2018 UA74_05630 96647c48adeabf59d50eb57baeb3a0c9 303 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 124 280 1.9E-52 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UA74_05630 96647c48adeabf59d50eb57baeb3a0c9 303 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UA74_05630 96647c48adeabf59d50eb57baeb3a0c9 303 Gene3D G3DSA:3.40.50.720 98 278 2.6E-92 T 12-10-2018 UA74_24375 28454bb6ece01fdf719ef26c046aed96 245 SUPERFAMILY SSF52317 35 212 1.05E-18 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_24375 28454bb6ece01fdf719ef26c046aed96 245 Gene3D G3DSA:3.40.50.880 25 212 5.9E-26 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_24375 28454bb6ece01fdf719ef26c046aed96 245 Pfam PF03575 Peptidase family S51 36 209 4.4E-25 T 12-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 UA74_25180 14b7d730bd3fe73c1713850ebd5e7a78 327 SUPERFAMILY SSF52833 25 145 2.61E-7 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_25180 14b7d730bd3fe73c1713850ebd5e7a78 327 Gene3D G3DSA:3.40.30.130 2 164 4.8E-59 T 12-10-2018 UA74_25180 14b7d730bd3fe73c1713850ebd5e7a78 327 Pfam PF13409 Glutathione S-transferase, N-terminal domain 49 141 7.0E-12 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 UA74_25180 14b7d730bd3fe73c1713850ebd5e7a78 327 Pfam PF13410 Glutathione S-transferase, C-terminal domain 190 260 5.2E-11 T 12-10-2018 UA74_25180 14b7d730bd3fe73c1713850ebd5e7a78 327 PIRSF PIRSF015753 2 310 1.6E-111 T 12-10-2018 IPR016639 Glutathione S-transferase Omega/GSH GO:0004364 UA74_25180 14b7d730bd3fe73c1713850ebd5e7a78 327 SUPERFAMILY SSF47616 162 324 5.85E-33 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily UA74_25180 14b7d730bd3fe73c1713850ebd5e7a78 327 Gene3D G3DSA:1.20.1050.10 165 327 8.8E-72 T 12-10-2018 UA74_12425 b1df46c0291fe151460feacd1136cd37 310 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 19 296 7.3E-96 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 UA74_12425 b1df46c0291fe151460feacd1136cd37 310 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 16 298 19.09 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 UA74_12425 b1df46c0291fe151460feacd1136cd37 310 Pfam PF01040 UbiA prenyltransferase family 32 270 1.7E-64 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 UA74_12425 b1df46c0291fe151460feacd1136cd37 310 Gene3D G3DSA:1.10.357.140 29 180 2.9E-17 T 12-10-2018 UA74_24585 e68aa41871cf7a604e03b39e3ad1b478 116 Gene3D G3DSA:3.30.370.10 20 109 1.8E-11 T 12-10-2018 IPR035905 Barstar-like superfamily UA74_24585 e68aa41871cf7a604e03b39e3ad1b478 116 Pfam PF01337 Barstar (barnase inhibitor) 23 101 1.2E-17 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) UA74_24585 e68aa41871cf7a604e03b39e3ad1b478 116 SUPERFAMILY SSF52038 22 103 1.44E-18 T 12-10-2018 IPR035905 Barstar-like superfamily UA74_13785 40b79eb443693a57775086ed9049b7a4 297 TIGRFAM TIGR02589 cas_Csd2: CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG 12 294 2.3E-81 T 12-10-2018 IPR013418 CRISPR-associated protein Csd2 UA74_13785 40b79eb443693a57775086ed9049b7a4 297 Pfam PF05107 CRISPR-associated protein Cas7 12 281 1.6E-82 T 12-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C UA74_13785 40b79eb443693a57775086ed9049b7a4 297 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 12 281 1.1E-61 T 12-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C UA74_24715 9ed86bca39608b038a6e40f31e99ba0c 369 SUPERFAMILY SSF55315 256 367 1.53E-7 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_24715 9ed86bca39608b038a6e40f31e99ba0c 369 Pfam PF03465 eRF1 domain 3 256 302 8.5E-5 T 12-10-2018 IPR005142 eRF1 domain 3 UA74_24715 9ed86bca39608b038a6e40f31e99ba0c 369 SUPERFAMILY SSF53137 132 221 1.22E-5 T 12-10-2018 UA74_24715 9ed86bca39608b038a6e40f31e99ba0c 369 Gene3D G3DSA:3.30.1330.30 252 313 5.7E-5 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_21680 d9e2fc93c18220cb1e1ada907c4c5c28 414 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 9 107 1.1E-15 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 UA74_21680 d9e2fc93c18220cb1e1ada907c4c5c28 414 Pfam PF07804 HipA-like C-terminal domain 138 370 1.5E-46 T 12-10-2018 IPR012893 HipA-like, C-terminal UA74_21680 d9e2fc93c18220cb1e1ada907c4c5c28 414 Pfam PF13657 HipA N-terminal domain 9 107 1.1E-22 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 UA74_22900 4bb2316f5b680dc9dc68ca580e432b02 322 Gene3D G3DSA:1.10.10.60 16 64 1.6E-12 T 12-10-2018 UA74_22900 4bb2316f5b680dc9dc68ca580e432b02 322 Pfam PF04198 Putative sugar-binding domain 74 321 5.3E-56 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 UA74_22900 4bb2316f5b680dc9dc68ca580e432b02 322 SUPERFAMILY SSF100950 75 320 7.53E-57 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_22900 4bb2316f5b680dc9dc68ca580e432b02 322 Gene3D G3DSA:3.40.50.1360 67 322 2.2E-70 T 12-10-2018 UA74_22225 7e37ee1cc1dd50f81e76316a6666a8bd 449 Pfam PF07690 Major Facilitator Superfamily 14 356 2.3E-24 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_22225 7e37ee1cc1dd50f81e76316a6666a8bd 449 Gene3D G3DSA:1.20.1250.20 3 394 2.6E-35 T 12-10-2018 UA74_22225 7e37ee1cc1dd50f81e76316a6666a8bd 449 SUPERFAMILY SSF103473 6 394 8.5E-38 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_21470 122755ff184d2168b20a843e6da8532e 313 Gene3D G3DSA:3.40.50.300 57 313 4.8E-82 T 12-10-2018 UA74_21470 122755ff184d2168b20a843e6da8532e 313 SUPERFAMILY SSF52540 62 312 7.93E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21470 122755ff184d2168b20a843e6da8532e 313 Pfam PF13614 AAA domain 63 239 2.9E-59 T 12-10-2018 IPR025669 AAA domain UA74_13140 be064ebfcc036c2f278092b260171ec2 304 Gene3D G3DSA:3.90.920.30 21 303 1.7E-85 T 12-10-2018 UA74_13140 be064ebfcc036c2f278092b260171ec2 304 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 15 263 8.5E-68 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 Gene3D G3DSA:4.10.1250.10 254 293 4.5E-12 T 12-10-2018 UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 SUPERFAMILY SSF103025 19 295 5.34E-87 T 12-10-2018 UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 Gene3D G3DSA:3.30.1360.120 22 250 2.2E-73 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 PIRSF PIRSF006487 2 382 4.3E-82 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 281 373 1.2E-20 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 SUPERFAMILY SSF101790 288 379 7.52E-22 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 20 378 5.8E-89 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 Gene3D G3DSA:2.40.30.110 297 382 2.0E-22 T 12-10-2018 UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 Hamap MF_00259 Aminomethyltransferase [gcvT]. 18 379 39.493 T 12-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 Gene3D G3DSA:3.30.70.1400 70 155 2.2E-73 T 12-10-2018 UA74_25045 5627731b6ebbf51bb03dc9cebcd1be9c 382 Pfam PF01571 Aminomethyltransferase folate-binding domain 24 274 8.0E-81 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain UA74_16080 683c8ffa56952faca48d46c4c38448d0 144 SUPERFAMILY SSF46785 10 120 7.24E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_16080 683c8ffa56952faca48d46c4c38448d0 144 Gene3D G3DSA:1.10.10.10 4 126 1.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16080 683c8ffa56952faca48d46c4c38448d0 144 Pfam PF01638 HxlR-like helix-turn-helix 16 114 1.4E-11 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_06880 39cb22e93e434444b7aff9582be52397 851 Gene3D G3DSA:3.20.20.80 427 739 1.2E-39 T 12-10-2018 UA74_06880 39cb22e93e434444b7aff9582be52397 851 SUPERFAMILY SSF51445 418 732 2.37E-26 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_06880 39cb22e93e434444b7aff9582be52397 851 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 422 629 1.5E-7 T 12-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 UA74_16590 090cec10bd4a7fe10bc7343fd189aec7 576 SMART SM00382 353 538 5.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_16590 090cec10bd4a7fe10bc7343fd189aec7 576 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_16590 090cec10bd4a7fe10bc7343fd189aec7 576 Gene3D G3DSA:3.40.50.300 323 572 3.4E-80 T 12-10-2018 UA74_16590 090cec10bd4a7fe10bc7343fd189aec7 576 Gene3D G3DSA:1.20.1560.10 1 312 3.1E-39 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_16590 090cec10bd4a7fe10bc7343fd189aec7 576 Pfam PF00664 ABC transporter transmembrane region 15 277 1.2E-16 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_16590 090cec10bd4a7fe10bc7343fd189aec7 576 SUPERFAMILY SSF90123 3 311 4.58E-43 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_16590 090cec10bd4a7fe10bc7343fd189aec7 576 Pfam PF00005 ABC transporter 344 492 3.9E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_16590 090cec10bd4a7fe10bc7343fd189aec7 576 SUPERFAMILY SSF52540 319 563 2.49E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 6.1E-15 T 12-10-2018 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 6.1E-15 T 12-10-2018 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 6.1E-15 T 12-10-2018 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 6.1E-15 T 12-10-2018 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.3E-19 T 12-10-2018 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 3.3E-19 T 12-10-2018 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.3E-19 T 12-10-2018 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 3.3E-19 T 12-10-2018 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.3E-19 T 12-10-2018 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 Pfam PF14759 Reductase C-terminal 328 396 2.2E-12 T 12-10-2018 IPR028202 Reductase, C-terminal UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 Gene3D G3DSA:3.50.50.60 120 246 5.9E-103 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 SUPERFAMILY SSF55424 321 397 2.33E-19 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 308 8.1E-53 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 Gene3D G3DSA:3.50.50.60 11 309 5.9E-103 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 SUPERFAMILY SSF51905 9 196 3.08E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 Gene3D G3DSA:3.30.390.30 328 402 1.9E-13 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UA74_07665 a6c3c842612f8339fffe14f6477f7412 404 SUPERFAMILY SSF51905 149 317 2.04E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_27705 b33fb527efce506bce1d02c7f6648165 481 SUPERFAMILY SSF103473 10 434 4.58E-46 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_27705 b33fb527efce506bce1d02c7f6648165 481 Pfam PF07690 Major Facilitator Superfamily 13 393 6.7E-22 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_24885 dec9340848893aa61586faa2f75c1fc7 344 Gene3D G3DSA:3.90.1720.10 137 341 5.1E-49 T 12-10-2018 UA74_24885 dec9340848893aa61586faa2f75c1fc7 344 Pfam PF00877 NlpC/P60 family 240 330 5.3E-24 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UA74_24885 dec9340848893aa61586faa2f75c1fc7 344 SUPERFAMILY SSF54001 219 330 4.17E-38 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UA74_27245 24a66eed83993b6b5e62a906fee38753 234 SUPERFAMILY SSF46689 34 119 1.99E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_27245 24a66eed83993b6b5e62a906fee38753 234 Gene3D G3DSA:1.10.357.10 33 229 4.9E-44 T 12-10-2018 UA74_27245 24a66eed83993b6b5e62a906fee38753 234 Pfam PF13305 WHG domain 122 205 4.7E-14 T 12-10-2018 IPR025996 WHG domain UA74_27245 24a66eed83993b6b5e62a906fee38753 234 SUPERFAMILY SSF48498 117 223 1.96E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_27245 24a66eed83993b6b5e62a906fee38753 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 94 1.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_14960 b59fa720c26fd07dbc9c890e2881d814 205 SUPERFAMILY SSF101262 3 202 2.22E-40 T 12-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 UA74_14960 b59fa720c26fd07dbc9c890e2881d814 205 Pfam PF04961 Formiminotransferase-cyclodeaminase 5 183 1.1E-48 T 12-10-2018 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 UA74_14960 b59fa720c26fd07dbc9c890e2881d814 205 Gene3D G3DSA:1.20.120.680 5 204 1.3E-51 T 12-10-2018 IPR036178 Formimidoyltransferase-cyclodeaminase-like superfamily GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|Reactome: R-HSA-70921 UA74_28785 baee57ab1d8da39702198e7e1aff9f6f 283 Gene3D G3DSA:3.90.550.10 26 276 2.3E-31 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_28785 baee57ab1d8da39702198e7e1aff9f6f 283 Pfam PF00535 Glycosyl transferase family 2 66 182 3.1E-20 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_28785 baee57ab1d8da39702198e7e1aff9f6f 283 SUPERFAMILY SSF53448 64 263 3.38E-33 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:2.170.160.10 344 576 1.2E-288 T 12-10-2018 IPR023309 Endoglucanase F, domain 2 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Pfam PF00553 Cellulose binding domain 42 142 4.9E-36 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 107 120 - T 12-10-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 SUPERFAMILY SSF49384 41 142 9.07E-32 T 12-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 SMART SM00637 42 142 1.8E-49 T 12-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 SUPERFAMILY SSF48208 253 893 5.02E-267 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:2.60.40.290 36 143 5.4E-36 T 12-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Pfam PF02011 Glycosyl hydrolase family 48 257 891 5.8E-289 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 283 308 1.5E-93 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 660 686 1.5E-93 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 470 497 1.5E-93 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 824 852 1.5E-93 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 614 637 1.5E-93 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 715 735 1.5E-93 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 309 326 1.5E-93 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 425 449 1.5E-93 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 PRINTS PR00844 Glycosyl hydrolase family 48 signature 543 562 1.5E-93 T 12-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:4.10.870.10 803 874 1.2E-288 T 12-10-2018 IPR027390 Endoglucanase F, domain 3 UA74_21060 b68b9d5933f2815b6e1a7ab3ee5e5ed4 895 Gene3D G3DSA:1.50.10.10 257 891 1.2E-288 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_27150 f5f028be3153445f4968f157a97ed759 479 TIGRFAM TIGR01312 XylB: xylulokinase 5 428 2.8E-123 T 12-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 UA74_27150 f5f028be3153445f4968f157a97ed759 479 PIRSF PIRSF000538 1 465 2.4E-84 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_27150 f5f028be3153445f4968f157a97ed759 479 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 243 425 3.6E-27 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UA74_27150 f5f028be3153445f4968f157a97ed759 479 SUPERFAMILY SSF53067 237 428 2.86E-41 T 12-10-2018 UA74_27150 f5f028be3153445f4968f157a97ed759 479 Gene3D G3DSA:3.30.420.40 237 468 9.0E-68 T 12-10-2018 UA74_27150 f5f028be3153445f4968f157a97ed759 479 PRINTS PR00301 70kDa heat shock protein signature 3 16 4.0E-5 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_27150 f5f028be3153445f4968f157a97ed759 479 PRINTS PR00301 70kDa heat shock protein signature 408 428 4.0E-5 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_27150 f5f028be3153445f4968f157a97ed759 479 PRINTS PR00301 70kDa heat shock protein signature 378 394 4.0E-5 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UA74_27150 f5f028be3153445f4968f157a97ed759 479 Gene3D G3DSA:3.30.420.40 1 235 1.5E-79 T 12-10-2018 UA74_27150 f5f028be3153445f4968f157a97ed759 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 214 7.2E-48 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UA74_27150 f5f028be3153445f4968f157a97ed759 479 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 337 358 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UA74_27150 f5f028be3153445f4968f157a97ed759 479 SUPERFAMILY SSF53067 4 236 2.47E-51 T 12-10-2018 UA74_26745 f5fc74bded1974fda8802fafa9ffac80 436 SUPERFAMILY SSF52540 43 372 2.15E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26745 f5fc74bded1974fda8802fafa9ffac80 436 Gene3D G3DSA:3.40.50.300 2 166 1.4E-5 T 12-10-2018 UA74_26745 f5fc74bded1974fda8802fafa9ffac80 436 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 43 149 2.8E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_26745 f5fc74bded1974fda8802fafa9ffac80 436 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 216 368 5.0E-17 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_04520 d629f91113218c6acb7fc9a158525c73 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 122 7.5E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_04520 d629f91113218c6acb7fc9a158525c73 129 Gene3D G3DSA:3.10.180.10 5 129 5.8E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_04520 d629f91113218c6acb7fc9a158525c73 129 SUPERFAMILY SSF54593 8 128 3.49E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_04980 3d6f6e5d0617877883b92616c2454812 618 PRINTS PR01607 Apyrase family signature 270 293 7.1E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 PRINTS PR01607 Apyrase family signature 250 267 7.1E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 PRINTS PR01607 Apyrase family signature 43 61 7.1E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 PRINTS PR01607 Apyrase family signature 549 568 7.1E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 PRINTS PR01607 Apyrase family signature 455 478 7.1E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 PRINTS PR01607 Apyrase family signature 318 338 7.1E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 Gene3D G3DSA:3.90.780.10 388 614 2.9E-45 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 Pfam PF02872 5'-nucleotidase, C-terminal domain 389 572 6.6E-28 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 SUPERFAMILY SSF56300 43 379 6.32E-46 T 12-10-2018 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 ProSitePatterns PS00786 5'-nucleotidase signature 2. 146 157 - T 12-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_04980 3d6f6e5d0617877883b92616c2454812 618 Gene3D G3DSA:3.60.21.10 43 381 2.6E-59 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_04980 3d6f6e5d0617877883b92616c2454812 618 SUPERFAMILY SSF55816 388 595 5.89E-30 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UA74_10730 74cf5c53dd005fe32a984efbfd0cbba0 177 Gene3D G3DSA:3.40.630.30 4 175 1.4E-38 T 12-10-2018 UA74_10730 74cf5c53dd005fe32a984efbfd0cbba0 177 SUPERFAMILY SSF55729 4 175 1.1E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_10730 74cf5c53dd005fe32a984efbfd0cbba0 177 Pfam PF00583 Acetyltransferase (GNAT) family 41 149 1.3E-12 T 12-10-2018 IPR000182 GNAT domain UA74_16340 8d19aa10c8e922f0f017c2004ee5c7f0 679 Gene3D G3DSA:2.180.10.10 129 235 7.7E-12 T 12-10-2018 UA74_16340 8d19aa10c8e922f0f017c2004ee5c7f0 679 SUPERFAMILY SSF51294 439 579 4.32E-20 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_16340 8d19aa10c8e922f0f017c2004ee5c7f0 679 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 157 236 1.6E-18 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 UA74_16340 8d19aa10c8e922f0f017c2004ee5c7f0 679 SMART SM00306 436 538 6.5E-14 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_16340 8d19aa10c8e922f0f017c2004ee5c7f0 679 Gene3D G3DSA:2.170.16.10 435 580 4.7E-43 T 12-10-2018 UA74_16340 8d19aa10c8e922f0f017c2004ee5c7f0 679 Pfam PF07591 Pretoxin HINT domain 447 581 6.0E-20 T 12-10-2018 UA74_18155 c0e36ae2049c44df1698a6db2c5b9c77 275 SUPERFAMILY SSF161098 4 274 2.8E-63 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18155 c0e36ae2049c44df1698a6db2c5b9c77 275 Gene3D G3DSA:1.10.3720.10 2 262 2.5E-51 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18155 c0e36ae2049c44df1698a6db2c5b9c77 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 268 4.2E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_20485 d9a0795938c2fd77827d6f699fab3919 187 Gene3D G3DSA:2.30.110.10 2 177 7.4E-47 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_20485 d9a0795938c2fd77827d6f699fab3919 187 SMART SM00903 22 169 1.4E-41 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 UA74_20485 d9a0795938c2fd77827d6f699fab3919 187 SUPERFAMILY SSF50475 16 170 1.18E-39 T 12-10-2018 UA74_20485 d9a0795938c2fd77827d6f699fab3919 187 Pfam PF01613 Flavin reductase like domain 22 170 1.2E-35 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 UA74_14565 c0dccec83476fd1708a98f7112161ed1 172 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 83 162 7.9E-36 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_14565 c0dccec83476fd1708a98f7112161ed1 172 SUPERFAMILY SSF53155 12 88 3.14E-19 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_14565 c0dccec83476fd1708a98f7112161ed1 172 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 84 164 9.4E-36 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UA74_14565 c0dccec83476fd1708a98f7112161ed1 172 SUPERFAMILY SSF46767 82 164 3.79E-34 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 UA74_14565 c0dccec83476fd1708a98f7112161ed1 172 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 13 79 1.4E-6 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_14565 c0dccec83476fd1708a98f7112161ed1 172 Gene3D G3DSA:3.30.160.70 10 78 3.5E-20 T 12-10-2018 UA74_14565 c0dccec83476fd1708a98f7112161ed1 172 Gene3D G3DSA:1.10.10.10 80 165 3.6E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14565 c0dccec83476fd1708a98f7112161ed1 172 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 14 163 44.86 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 UA74_14565 c0dccec83476fd1708a98f7112161ed1 172 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 133 139 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UA74_02555 1a76ac1e341d30d7fcd8271b58f9a5cc 441 SUPERFAMILY SSF51905 22 418 1.98E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_02555 1a76ac1e341d30d7fcd8271b58f9a5cc 441 Gene3D G3DSA:3.50.50.60 20 428 7.7E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_02555 1a76ac1e341d30d7fcd8271b58f9a5cc 441 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 24 346 7.2E-73 T 12-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 UA74_02555 1a76ac1e341d30d7fcd8271b58f9a5cc 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 173 188 3.4E-14 T 12-10-2018 UA74_02555 1a76ac1e341d30d7fcd8271b58f9a5cc 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 3.4E-14 T 12-10-2018 UA74_02555 1a76ac1e341d30d7fcd8271b58f9a5cc 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 23 45 3.4E-14 T 12-10-2018 UA74_02555 1a76ac1e341d30d7fcd8271b58f9a5cc 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 326 3.4E-14 T 12-10-2018 UA74_02555 1a76ac1e341d30d7fcd8271b58f9a5cc 441 Pfam PF01494 FAD binding domain 22 340 2.5E-19 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_08455 b99402d32aaae600f34da9e6a6f202d1 100 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 5.0E-45 T 12-10-2018 IPR025242 Protein of unknown function DUF4193 UA74_07940 f56d80c03c4b4335d1c93e35fb3d527c 164 Pfam PF17174 Domain of unknown function (DUF5130) 18 154 4.4E-33 T 12-10-2018 IPR033437 Protein of unknown function DUF5130 UA74_07940 f56d80c03c4b4335d1c93e35fb3d527c 164 Gene3D G3DSA:3.10.310.50 42 162 4.3E-6 T 12-10-2018 UA74_13920 bb6e9220751bff6fde67e416ddaf7b43 301 Gene3D G3DSA:2.60.120.200 27 300 3.9E-57 T 12-10-2018 UA74_13920 bb6e9220751bff6fde67e416ddaf7b43 301 Pfam PF00722 Glycosyl hydrolases family 16 84 265 3.3E-21 T 12-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 UA74_13920 bb6e9220751bff6fde67e416ddaf7b43 301 SUPERFAMILY SSF49899 30 301 5.12E-54 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UA74_00160 057e2b8b9853d31f67aea601035671c3 399 Pfam PF00498 FHA domain 327 389 1.2E-16 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_00160 057e2b8b9853d31f67aea601035671c3 399 SMART SM00240 325 375 4.9E-13 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 UA74_00160 057e2b8b9853d31f67aea601035671c3 399 Pfam PF12401 Protein of unknown function (DUF2662) 4 117 7.2E-43 T 12-10-2018 IPR022128 Domain of unknown function DUF3662 UA74_00160 057e2b8b9853d31f67aea601035671c3 399 SUPERFAMILY SSF49879 271 396 3.63E-29 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 UA74_00160 057e2b8b9853d31f67aea601035671c3 399 Gene3D G3DSA:2.60.200.20 282 398 7.9E-28 T 12-10-2018 UA74_00160 057e2b8b9853d31f67aea601035671c3 399 Gene3D G3DSA:3.30.2320.60 1 128 1.1E-50 T 12-10-2018 UA74_21905 fb594e56f02ec218d42352d043bb642a 275 Gene3D G3DSA:3.40.50.720 52 259 6.3E-36 T 12-10-2018 UA74_21905 fb594e56f02ec218d42352d043bb642a 275 Gene3D G3DSA:3.90.25.10 130 260 6.3E-36 T 12-10-2018 UA74_21905 fb594e56f02ec218d42352d043bb642a 275 SUPERFAMILY SSF51735 52 243 4.35E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_17090 deefaf9775217ce6a671d21277b71e4a 156 PIRSF PIRSF005384 1 148 8.7E-47 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_17090 deefaf9775217ce6a671d21277b71e4a 156 Gene3D G3DSA:3.40.1400.10 1 155 2.3E-49 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_17090 deefaf9775217ce6a671d21277b71e4a 156 SUPERFAMILY SSF89623 1 144 8.76E-48 T 12-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_17090 deefaf9775217ce6a671d21277b71e4a 156 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 1.8E-39 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_17090 deefaf9775217ce6a671d21277b71e4a 156 Pfam PF02502 Ribose/Galactose Isomerase 3 141 8.5E-45 T 12-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 Pfam PF07732 Multicopper oxidase 71 107 4.6E-5 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 Pfam PF07732 Multicopper oxidase 144 213 3.1E-7 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 SUPERFAMILY SSF49503 217 589 1.44E-30 T 12-10-2018 IPR008972 Cupredoxin UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 Pfam PF07731 Multicopper oxidase 466 586 3.0E-21 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 Gene3D G3DSA:2.60.40.420 24 210 7.1E-56 T 12-10-2018 IPR008972 Cupredoxin UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 ProSitePatterns PS00079 Multicopper oxidases signature 1. 561 581 - T 12-10-2018 IPR033138 Multicopper oxidases, conserved site UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 ProSitePatterns PS00080 Multicopper oxidases signature 2. 566 577 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 Gene3D G3DSA:2.60.40.420 390 607 7.1E-55 T 12-10-2018 IPR008972 Cupredoxin UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 SUPERFAMILY SSF49503 39 214 4.03E-23 T 12-10-2018 IPR008972 Cupredoxin UA74_11465 1572e505665077cfd4f48f4f33e28b5d 614 Gene3D G3DSA:2.60.40.420 211 388 1.6E-56 T 12-10-2018 IPR008972 Cupredoxin UA74_04805 e34e7cf924e742fa162b45e50fdbb4ea 556 Pfam PF09972 Predicted membrane protein (DUF2207) 27 497 2.9E-44 T 12-10-2018 IPR018702 Protein of unknown function DUF2207, membrane UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 SUPERFAMILY SSF48557 14 464 1.43E-129 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Hamap MF_00006 Argininosuccinate lyase [argH]. 10 462 38.99 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 1.2E-26 T 12-10-2018 IPR000362 Fumarate lyase family UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 1.2E-26 T 12-10-2018 IPR000362 Fumarate lyase family UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 1.2E-26 T 12-10-2018 IPR000362 Fumarate lyase family UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 1.2E-26 T 12-10-2018 IPR000362 Fumarate lyase family UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Pfam PF14698 Argininosuccinate lyase C-terminal 372 440 2.4E-22 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 1.1E-52 T 12-10-2018 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 1.1E-52 T 12-10-2018 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 1.1E-52 T 12-10-2018 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 1.1E-52 T 12-10-2018 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 1.1E-52 T 12-10-2018 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 1.1E-52 T 12-10-2018 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 TIGRFAM TIGR00838 argH: argininosuccinate lyase 11 460 1.8E-175 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Gene3D G3DSA:1.10.40.30 371 441 1.7E-129 T 12-10-2018 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Gene3D G3DSA:1.10.275.50 8 115 3.2E-30 T 12-10-2018 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Gene3D G3DSA:1.20.200.10 116 454 1.7E-129 T 12-10-2018 UA74_21600 a6cf4dd2b5cb9610887c0f8dfeee18f1 477 Pfam PF00206 Lyase 15 309 5.4E-60 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal UA74_04515 1aa97cdde6b2a79ebe13a436e82c4f25 63 Pfam PF04149 Domain of unknown function (DUF397) 4 54 2.3E-13 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_04490 9357767781318f0caff4f3e02fd7ee4c 262 Pfam PF14011 EspG family 14 254 6.6E-51 T 12-10-2018 IPR025734 EspG family UA74_22615 b0f02db4a7e563312a269c5aa7f45b29 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 5.9E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22615 b0f02db4a7e563312a269c5aa7f45b29 215 Gene3D G3DSA:1.10.357.10 2 214 1.1E-76 T 12-10-2018 UA74_22615 b0f02db4a7e563312a269c5aa7f45b29 215 SUPERFAMILY SSF48498 91 214 7.78E-30 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_22615 b0f02db4a7e563312a269c5aa7f45b29 215 SUPERFAMILY SSF46689 10 81 1.6E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_08380 f4a870c223891088d6270ba481554f62 307 SUPERFAMILY SSF110581 5 304 1.96E-94 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 UA74_08380 f4a870c223891088d6270ba481554f62 307 Pfam PF04227 Indigoidine synthase A like protein 11 302 1.4E-111 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 UA74_08380 f4a870c223891088d6270ba481554f62 307 Gene3D G3DSA:3.40.1790.10 1 306 2.2E-112 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 UA74_08380 f4a870c223891088d6270ba481554f62 307 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 10 305 37.483 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 UA74_19305 6c424284a044a156c40392a7c8aae7fa 157 SUPERFAMILY SSF50475 3 150 1.18E-37 T 12-10-2018 UA74_19305 6c424284a044a156c40392a7c8aae7fa 157 SMART SM00903 10 152 2.0E-36 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 UA74_19305 6c424284a044a156c40392a7c8aae7fa 157 Pfam PF01613 Flavin reductase like domain 10 151 1.3E-26 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 UA74_19305 6c424284a044a156c40392a7c8aae7fa 157 Gene3D G3DSA:2.30.110.10 1 155 2.2E-38 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_27045 33489344b246cb37659a4da4ac3f19a0 465 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 369 8.5E-59 T 12-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 UA74_27045 33489344b246cb37659a4da4ac3f19a0 465 Gene3D G3DSA:3.40.720.10 1 265 5.8E-37 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UA74_27045 33489344b246cb37659a4da4ac3f19a0 465 SUPERFAMILY SSF53649 2 355 1.27E-74 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UA74_27045 33489344b246cb37659a4da4ac3f19a0 465 Gene3D G3DSA:3.30.1360.110 281 349 3.2E-6 T 12-10-2018 IPR023116 Phosphonoacetate hydrolase, insert domain superfamily KEGG: 00440+3.11.1.2 UA74_13015 6d2f9647d835593dfb7d58da55352c4a 197 Gene3D G3DSA:1.10.10.10 92 191 2.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_13015 6d2f9647d835593dfb7d58da55352c4a 197 SMART SM00862 110 184 2.0E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_13015 6d2f9647d835593dfb7d58da55352c4a 197 SUPERFAMILY SSF46894 96 184 2.04E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_13015 6d2f9647d835593dfb7d58da55352c4a 197 Pfam PF00486 Transcriptional regulatory protein, C terminal 111 184 1.6E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_21720 1110ab0f6cea64abbce89e532f1c1564 264 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 40 172 4.1E-21 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_21720 1110ab0f6cea64abbce89e532f1c1564 264 SUPERFAMILY SSF109854 31 178 9.84E-37 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_21720 1110ab0f6cea64abbce89e532f1c1564 264 SUPERFAMILY SSF55718 181 263 2.24E-9 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily UA74_21720 1110ab0f6cea64abbce89e532f1c1564 264 Gene3D G3DSA:1.20.120.450 26 177 5.5E-43 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_21720 1110ab0f6cea64abbce89e532f1c1564 264 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 40 247 8.9E-26 T 12-10-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type UA74_21175 008dd4d84b6a2eea0f425629cf5b9f13 249 Pfam PF13398 Peptidase M50B-like 39 239 2.9E-57 T 12-10-2018 UA74_13370 c6eb0cd2c8f40aa0d4bbc881d5bcc1e6 163 Gene3D G3DSA:1.20.120.450 12 162 6.7E-25 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_13370 c6eb0cd2c8f40aa0d4bbc881d5bcc1e6 163 Pfam PF04978 Protein of unknown function (DUF664) 22 159 1.1E-36 T 12-10-2018 IPR007061 Protein of unknown function DUF664 UA74_13370 c6eb0cd2c8f40aa0d4bbc881d5bcc1e6 163 SUPERFAMILY SSF109854 6 158 6.78E-35 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_01360 7753a528219277fe6dbd6c5035d51855 271 Pfam PF14011 EspG family 13 262 8.6E-48 T 12-10-2018 IPR025734 EspG family UA74_24615 85150cd791a31b4d251a2557a25b2e55 251 Pfam PF14325 Domain of unknown function (DUF4383) 18 132 7.9E-12 T 12-10-2018 IPR025492 Protein of unknown function DUF4383 UA74_18590 3267ecb6fe68da1f51c1a5fcc0d232ce 348 Pfam PF08012 Protein of unknown function (DUF1702) 5 336 3.8E-124 T 12-10-2018 IPR012964 Protein of unknown function DUF1702 UA74_01205 21dd525c5175b7cbc6e02805a4da6c99 157 SUPERFAMILY SSF55298 8 156 3.46E-55 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_01205 21dd525c5175b7cbc6e02805a4da6c99 157 Gene3D G3DSA:3.30.1330.40 1 157 1.2E-60 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_01205 21dd525c5175b7cbc6e02805a4da6c99 157 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 11 155 5.3E-30 T 12-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like UA74_17620 351f32961885ceeb438321d7c1008821 465 SUPERFAMILY SSF51905 8 352 3.53E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17620 351f32961885ceeb438321d7c1008821 465 Pfam PF12831 FAD dependent oxidoreductase 10 179 3.6E-8 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal UA74_17620 351f32961885ceeb438321d7c1008821 465 Gene3D G3DSA:3.50.50.60 8 362 2.1E-21 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_21290 6bd9cbdea80db9d54af4e959d875d97e 328 Pfam PF09851 Short C-terminal domain 299 325 6.2E-8 T 12-10-2018 IPR018649 SHOCT domain UA74_21290 6bd9cbdea80db9d54af4e959d875d97e 328 Pfam PF14472 Domain of unknown function (DUF4429) 39 131 4.0E-7 T 12-10-2018 IPR027860 Domain of unknown function DUF4429 UA74_21290 6bd9cbdea80db9d54af4e959d875d97e 328 Pfam PF14472 Domain of unknown function (DUF4429) 167 251 1.0E-9 T 12-10-2018 IPR027860 Domain of unknown function DUF4429 UA74_01500 b47e3db4e92631ed02a5d8f48f618204 600 Gene3D G3DSA:1.20.1720.10 28 235 2.4E-50 T 12-10-2018 UA74_01500 b47e3db4e92631ed02a5d8f48f618204 600 SUPERFAMILY SSF103473 21 536 4.32E-66 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_01500 b47e3db4e92631ed02a5d8f48f618204 600 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 535 3.8E-75 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UA74_01500 b47e3db4e92631ed02a5d8f48f618204 600 Pfam PF07690 Major Facilitator Superfamily 31 429 1.1E-50 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_14195 08686321a46e6732f7332cfd7960af03 204 Pfam PF01183 Glycosyl hydrolases family 25 6 183 7.8E-31 T 12-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 UA74_14195 08686321a46e6732f7332cfd7960af03 204 SMART SM00641 3 109 2.8E-4 T 12-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup UA74_14195 08686321a46e6732f7332cfd7960af03 204 Gene3D G3DSA:3.20.20.80 2 196 3.8E-43 T 12-10-2018 UA74_14195 08686321a46e6732f7332cfd7960af03 204 SUPERFAMILY SSF51445 2 195 7.72E-41 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_14710 bafa961c1a9f8d41c56556ebfc4a70ac 253 SUPERFAMILY SSF52540 27 163 4.48E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_14710 bafa961c1a9f8d41c56556ebfc4a70ac 253 Gene3D G3DSA:3.40.50.300 19 164 3.1E-19 T 12-10-2018 UA74_14710 bafa961c1a9f8d41c56556ebfc4a70ac 253 Pfam PF00265 Thymidine kinase 27 191 7.2E-20 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 Gene3D G3DSA:3.50.50.60 9 362 9.7E-103 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 Gene3D G3DSA:3.40.30.120 391 527 1.4E-33 T 12-10-2018 UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 Pfam PF01494 FAD binding domain 8 366 1.5E-93 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 7.4E-40 T 12-10-2018 UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 354 7.4E-40 T 12-10-2018 UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 318 7.4E-40 T 12-10-2018 UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 7.4E-40 T 12-10-2018 UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 354 370 7.4E-40 T 12-10-2018 UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 7.4E-40 T 12-10-2018 UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 SUPERFAMILY SSF51905 8 380 6.65E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_10930 9f381b6d767ff159a5de6f8992aa5a76 532 Gene3D G3DSA:3.30.9.50 75 300 9.7E-103 T 12-10-2018 UA74_20530 a2631862e78b6b38bb85dcb83bdae979 268 Gene3D G3DSA:3.30.1380.10 123 266 1.2E-17 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_20530 a2631862e78b6b38bb85dcb83bdae979 268 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 188 267 1.9E-20 T 12-10-2018 IPR039561 Peptidase M15C GO:0008233 UA74_20530 a2631862e78b6b38bb85dcb83bdae979 268 SUPERFAMILY SSF55166 113 266 1.29E-29 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_27225 895b644f6e688286eb32524cf2d57e04 328 Gene3D G3DSA:3.20.20.100 4 327 1.7E-118 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_27225 895b644f6e688286eb32524cf2d57e04 328 Pfam PF00248 Aldo/keto reductase family 18 307 3.2E-74 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_27225 895b644f6e688286eb32524cf2d57e04 328 SUPERFAMILY SSF51430 11 308 3.8E-98 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_19360 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19360 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19360 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19360 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19360 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19360 04f435da28174017dbf8360928122fe1 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.9E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19360 04f435da28174017dbf8360928122fe1 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 2.0E-53 T 12-10-2018 UA74_19360 04f435da28174017dbf8360928122fe1 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 186 0.0012 T 12-10-2018 UA74_19360 04f435da28174017dbf8360928122fe1 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19360 04f435da28174017dbf8360928122fe1 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19360 04f435da28174017dbf8360928122fe1 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_19360 04f435da28174017dbf8360928122fe1 244 Gene3D G3DSA:3.40.50.720 2 243 2.4E-76 T 12-10-2018 UA74_19360 04f435da28174017dbf8360928122fe1 244 SUPERFAMILY SSF51735 5 243 1.18E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_19360 04f435da28174017dbf8360928122fe1 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_17195 c4f79594b21aa9fe31dfe752384a5771 89 SMART SM00530 20 74 6.1E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_17195 c4f79594b21aa9fe31dfe752384a5771 89 SUPERFAMILY SSF47413 11 77 1.63E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_17195 c4f79594b21aa9fe31dfe752384a5771 89 Pfam PF13560 Helix-turn-helix domain 16 75 3.5E-11 T 12-10-2018 UA74_17195 c4f79594b21aa9fe31dfe752384a5771 89 Gene3D G3DSA:1.10.260.40 7 76 6.9E-27 T 12-10-2018 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 24 657 4.8E-220 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 187 208 2.6E-57 T 12-10-2018 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 274 300 2.6E-57 T 12-10-2018 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 128 2.6E-57 T 12-10-2018 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 252 273 2.6E-57 T 12-10-2018 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 449 468 2.6E-57 T 12-10-2018 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 342 354 2.6E-57 T 12-10-2018 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 Pfam PF00361 Proton-conducting membrane transporter 164 450 1.4E-85 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 85 151 3.2E-23 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 105 125 2.1E-13 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 448 470 2.1E-13 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 79 103 2.1E-13 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UA74_02615 7cb3a0a213607aa54f9e2ebb72b0702a 663 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 292 314 2.1E-13 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UA74_06010 4e822f14c1400754880e4c74745f551f 205 SUPERFAMILY SSF48498 82 197 1.47E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_06010 4e822f14c1400754880e4c74745f551f 205 Gene3D G3DSA:1.10.357.10 1 202 6.3E-43 T 12-10-2018 UA74_06010 4e822f14c1400754880e4c74745f551f 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 58 6.3E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06010 4e822f14c1400754880e4c74745f551f 205 SUPERFAMILY SSF46689 4 66 4.04E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14790 ee70d399476bad61df6bf219a50a6303 339 SUPERFAMILY SSF53686 8 317 5.04E-45 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_14790 ee70d399476bad61df6bf219a50a6303 339 PIRSF PIRSF006278 1 327 5.8E-45 T 12-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase UA74_14790 ee70d399476bad61df6bf219a50a6303 339 Gene3D G3DSA:3.40.50.1100 8 317 1.0E-65 T 12-10-2018 UA74_14790 ee70d399476bad61df6bf219a50a6303 339 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 14 317 2.7E-28 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_14790 ee70d399476bad61df6bf219a50a6303 339 Gene3D G3DSA:3.40.50.1100 62 156 1.0E-65 T 12-10-2018 UA74_15265 274dfa21b9750701ad4b5d484c069c2e 237 Pfam PF00005 ABC transporter 18 156 6.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_15265 274dfa21b9750701ad4b5d484c069c2e 237 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_15265 274dfa21b9750701ad4b5d484c069c2e 237 Gene3D G3DSA:3.40.50.300 1 229 1.2E-57 T 12-10-2018 UA74_15265 274dfa21b9750701ad4b5d484c069c2e 237 SUPERFAMILY SSF52540 2 219 7.26E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15265 274dfa21b9750701ad4b5d484c069c2e 237 SMART SM00382 26 204 3.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_04235 0d5973caee409331331ff0836da31dba 177 Pfam PF02575 YbaB/EbfC DNA-binding family 26 114 7.9E-14 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_04235 0d5973caee409331331ff0836da31dba 177 Gene3D G3DSA:3.30.1310.10 17 121 3.6E-11 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_04235 0d5973caee409331331ff0836da31dba 177 SUPERFAMILY SSF82607 23 112 1.05E-8 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_22415 1c92b083b04a70e85b3faf8274606c2d 382 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.1E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22415 1c92b083b04a70e85b3faf8274606c2d 382 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22415 1c92b083b04a70e85b3faf8274606c2d 382 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22415 1c92b083b04a70e85b3faf8274606c2d 382 SUPERFAMILY SSF46689 4 71 2.82E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_22415 1c92b083b04a70e85b3faf8274606c2d 382 Gene3D G3DSA:1.10.357.10 1 206 4.5E-20 T 12-10-2018 UA74_01180 6c99245f06807982d216ea3ed8a647d0 100 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 2 75 18.376 T 12-10-2018 IPR003482 Transcription factor WhiB UA74_01180 6c99245f06807982d216ea3ed8a647d0 100 Pfam PF02467 Transcription factor WhiB 8 70 2.0E-23 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain UA74_27170 3a0cc38fe40188d9f95328894ac99473 120 Pfam PF03334 Na+/H+ antiporter subunit 11 89 3.6E-24 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 UA74_27170 3a0cc38fe40188d9f95328894ac99473 120 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 103 2.7E-22 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 UA74_21635 afe4a3755df4907b3ae9f4031e18fc07 342 Gene3D G3DSA:3.30.360.10 150 315 9.9E-115 T 12-10-2018 UA74_21635 afe4a3755df4907b3ae9f4031e18fc07 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 313 2.0E-17 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_21635 afe4a3755df4907b3ae9f4031e18fc07 342 SUPERFAMILY SSF55347 146 310 7.19E-44 T 12-10-2018 UA74_21635 afe4a3755df4907b3ae9f4031e18fc07 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 38.892 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_21635 afe4a3755df4907b3ae9f4031e18fc07 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 129 5.1E-25 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UA74_21635 afe4a3755df4907b3ae9f4031e18fc07 342 SMART SM00859 4 136 1.6E-44 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UA74_21635 afe4a3755df4907b3ae9f4031e18fc07 342 SUPERFAMILY SSF51735 3 170 2.77E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_21635 afe4a3755df4907b3ae9f4031e18fc07 342 Gene3D G3DSA:3.40.50.720 5 328 9.9E-115 T 12-10-2018 UA74_21635 afe4a3755df4907b3ae9f4031e18fc07 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 342 1.6E-112 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UA74_01330 d64de7d4255b075e5fb7106826d9da71 263 Gene3D G3DSA:3.60.110.10 1 263 7.5E-65 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UA74_01330 d64de7d4255b075e5fb7106826d9da71 263 SUPERFAMILY SSF56317 1 261 3.53E-58 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UA74_01330 d64de7d4255b075e5fb7106826d9da71 263 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 138 158 - T 12-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site UA74_01330 d64de7d4255b075e5fb7106826d9da71 263 Pfam PF00795 Carbon-nitrogen hydrolase 2 252 1.2E-31 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 UA74_02005 03149d57ebf06bccd26dc656101f3223 433 Gene3D G3DSA:3.30.565.10 320 431 7.2E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_02005 03149d57ebf06bccd26dc656101f3223 433 SUPERFAMILY SSF55874 342 430 5.02E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_02005 03149d57ebf06bccd26dc656101f3223 433 Pfam PF07730 Histidine kinase 219 284 4.5E-14 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_02005 03149d57ebf06bccd26dc656101f3223 433 SMART SM00387 343 433 2.8E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_02005 03149d57ebf06bccd26dc656101f3223 433 Pfam PF13796 Putative sensor 19 190 1.9E-18 T 12-10-2018 IPR025828 Putative sensor domain UA74_23485 086dfd20643002522f79e1235bba6a16 300 Gene3D G3DSA:3.40.1190.20 5 300 2.5E-51 T 12-10-2018 IPR029056 Ribokinase-like UA74_23485 086dfd20643002522f79e1235bba6a16 300 Pfam PF00294 pfkB family carbohydrate kinase 18 282 1.7E-28 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_23485 086dfd20643002522f79e1235bba6a16 300 SUPERFAMILY SSF53613 21 289 4.21E-38 T 12-10-2018 IPR029056 Ribokinase-like UA74_23485 086dfd20643002522f79e1235bba6a16 300 PIRSF PIRSF000535 5 300 1.3E-37 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UA74_18300 05963f0b9e916f3792ee2157bfa2380d 242 SUPERFAMILY SSF52317 10 197 1.89E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_18300 05963f0b9e916f3792ee2157bfa2380d 242 Gene3D G3DSA:3.40.50.880 2 216 8.4E-66 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_18300 05963f0b9e916f3792ee2157bfa2380d 242 Pfam PF01965 DJ-1/PfpI family 10 175 9.2E-25 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UA74_24930 63401f5dec38df8f16208c949ee4dc07 136 SUPERFAMILY SSF52172 37 130 2.42E-6 T 12-10-2018 IPR011006 CheY-like superfamily UA74_24930 63401f5dec38df8f16208c949ee4dc07 136 Gene3D G3DSA:3.40.50.2300 2 131 3.5E-7 T 12-10-2018 UA74_05455 154518c35d7f7f722ff370afc038bc44 178 Pfam PF02575 YbaB/EbfC DNA-binding family 32 115 2.1E-11 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_05455 154518c35d7f7f722ff370afc038bc44 178 Gene3D G3DSA:3.30.1310.10 22 122 5.6E-11 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_05455 154518c35d7f7f722ff370afc038bc44 178 SUPERFAMILY SSF82607 34 117 4.05E-7 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_22495 b1d42848c08369dcb87da48118da0d6f 269 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22495 b1d42848c08369dcb87da48118da0d6f 269 Pfam PF00005 ABC transporter 22 177 2.3E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_22495 b1d42848c08369dcb87da48118da0d6f 269 SUPERFAMILY SSF52540 3 249 1.1E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22495 b1d42848c08369dcb87da48118da0d6f 269 Gene3D G3DSA:3.40.50.300 1 262 2.0E-76 T 12-10-2018 UA74_22495 b1d42848c08369dcb87da48118da0d6f 269 SMART SM00382 29 227 3.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_23185 6d5e9e641bbc2c437b7952c8e2c0630b 381 Pfam PF09344 CT1975-like protein 9 368 2.9E-104 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 UA74_23185 6d5e9e641bbc2c437b7952c8e2c0630b 381 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 8 333 2.3E-94 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 UA74_28270 d8597eca4d7b066c8468b98b1b622c74 338 Pfam PF11268 Protein of unknown function (DUF3071) 1 169 9.9E-61 T 12-10-2018 IPR021421 Protein of unknown function DUF3071 UA74_20690 98ac95a33de2fc933722bb941d56d04a 404 Pfam PF01757 Acyltransferase family 21 352 2.7E-25 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 SUPERFAMILY SSF53474 471 729 1.5E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 Gene3D G3DSA:2.130.10.120 278 462 1.7E-129 T 12-10-2018 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 SUPERFAMILY SSF50993 3 453 2.46E-39 T 12-10-2018 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 278 453 5.6E-18 T 12-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 5 204 1.3E-13 T 12-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 Gene3D G3DSA:3.40.50.1820 463 701 1.7E-129 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 504 522 1.7E-41 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 554 1.7E-41 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 662 684 1.7E-41 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 588 608 1.7E-41 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 643 658 1.7E-41 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 558 577 1.7E-41 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 Pfam PF00326 Prolyl oligopeptidase family 527 731 6.7E-50 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 Gene3D G3DSA:3.40.50.1820 1 88 5.4E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 Gene3D G3DSA:2.130.10.120 89 210 6.3E-19 T 12-10-2018 UA74_12790 da7d34d3a1a461933bcd1ad25d697839 793 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 565 595 - T 12-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 UA74_03450 8ba2019c96b6028deb23de655083e7bb 316 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 3 311 2.4E-106 T 12-10-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV-5884 family UA74_03450 8ba2019c96b6028deb23de655083e7bb 316 SUPERFAMILY SSF56059 130 312 7.34E-14 T 12-10-2018 UA74_03450 8ba2019c96b6028deb23de655083e7bb 316 Gene3D G3DSA:3.30.470.20 206 314 3.8E-13 T 12-10-2018 UA74_20125 ee3f7333b91697d1e025ec2c18c58020 317 SUPERFAMILY SSF161098 91 297 3.92E-16 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20125 ee3f7333b91697d1e025ec2c18c58020 317 Gene3D G3DSA:1.10.3720.10 85 307 1.6E-23 T 12-10-2018 IPR035906 MetI-like superfamily UA74_20125 ee3f7333b91697d1e025ec2c18c58020 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 4.9E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_02400 cc28f037277ed73d1742b6d57a06840f 612 Pfam PF05140 ResB-like family 26 513 2.8E-127 T 12-10-2018 IPR007816 ResB-like domain UA74_26520 c4d973f14a2ba4b33994accf98957105 227 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 227 23.015 T 12-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid UA74_26520 c4d973f14a2ba4b33994accf98957105 227 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 99 8.8E-22 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 UA74_26520 c4d973f14a2ba4b33994accf98957105 227 SUPERFAMILY SSF69754 1 106 7.06E-26 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like UA74_26520 c4d973f14a2ba4b33994accf98957105 227 Gene3D G3DSA:3.30.505.50 181 226 2.8E-18 T 12-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily UA74_26520 c4d973f14a2ba4b33994accf98957105 227 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 168 223 2.2E-22 T 12-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal UA74_26520 c4d973f14a2ba4b33994accf98957105 227 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 4.5E-29 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 UA74_26520 c4d973f14a2ba4b33994accf98957105 227 Gene3D G3DSA:3.30.160.100 3 103 5.7E-24 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like UA74_07390 a5d714cc30fa92653d4871e815a12683 112 SUPERFAMILY SSF46785 3 102 1.93E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_07390 a5d714cc30fa92653d4871e815a12683 112 Gene3D G3DSA:1.10.10.10 1 103 2.1E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_07390 a5d714cc30fa92653d4871e815a12683 112 SMART SM00418 2 83 1.5E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_07390 a5d714cc30fa92653d4871e815a12683 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 4.8E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_07390 a5d714cc30fa92653d4871e815a12683 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 4.8E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_07390 a5d714cc30fa92653d4871e815a12683 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 4.8E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_07390 a5d714cc30fa92653d4871e815a12683 112 Pfam PF12840 Helix-turn-helix domain 2 60 5.9E-15 T 12-10-2018 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 SUPERFAMILY SSF48264 4 379 2.62E-87 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 Gene3D G3DSA:1.10.630.10 1 377 2.2E-124 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 Pfam PF00067 Cytochrome P450 7 234 1.7E-6 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 Pfam PF00067 Cytochrome P450 247 346 5.9E-13 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 318 327 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00359 B-class P450 signature 265 292 3.5E-29 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00359 B-class P450 signature 325 336 3.5E-29 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00359 B-class P450 signature 165 187 3.5E-29 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00359 B-class P450 signature 247 258 3.5E-29 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00359 B-class P450 signature 316 325 3.5E-29 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00359 B-class P450 signature 128 143 3.5E-29 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00359 B-class P450 signature 111 127 3.5E-29 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00385 P450 superfamily signature 247 258 1.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00385 P450 superfamily signature 325 336 1.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00385 P450 superfamily signature 316 325 1.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_15990 4167df3cb4b2737780b18e244ccc2f6a 385 PRINTS PR00385 P450 superfamily signature 212 229 1.5E-5 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_23565 982f331e328ce4d2359a46c08f20f1b2 158 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 90 5.0E-14 T 12-10-2018 IPR024412 Lsr2 UA74_23565 982f331e328ce4d2359a46c08f20f1b2 158 Gene3D G3DSA:3.30.60.230 1 60 4.1E-25 T 12-10-2018 UA74_23565 982f331e328ce4d2359a46c08f20f1b2 158 Pfam PF11774 Lsr2 1 94 1.1E-23 T 12-10-2018 IPR024412 Lsr2 UA74_24405 5e1a5bec07c8d5515e6aeb657b6d717f 137 Pfam PF01475 Ferric uptake regulator family 13 129 7.0E-37 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 UA74_24405 5e1a5bec07c8d5515e6aeb657b6d717f 137 SUPERFAMILY SSF46785 13 135 2.44E-37 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24405 5e1a5bec07c8d5515e6aeb657b6d717f 137 Gene3D G3DSA:1.10.10.10 7 88 1.8E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24405 5e1a5bec07c8d5515e6aeb657b6d717f 137 Gene3D G3DSA:3.30.1490.190 89 137 2.5E-21 T 12-10-2018 UA74_09715 5676e77bcdbe06ed104b28bc285971fb 275 Pfam PF05103 DivIVA protein 3 64 5.8E-13 T 12-10-2018 IPR007793 DivIVA family UA74_09715 5676e77bcdbe06ed104b28bc285971fb 275 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 6.1E-15 T 12-10-2018 IPR019933 DivIVA domain UA74_09160 771b590aad906bb88715b188e149d372 462 SUPERFAMILY SSF53790 2 235 1.7E-50 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 UA74_09160 771b590aad906bb88715b188e149d372 462 Gene3D G3DSA:3.30.950.10 115 234 3.4E-33 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 UA74_09160 771b590aad906bb88715b188e149d372 462 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UA74_09160 771b590aad906bb88715b188e149d372 462 Gene3D G3DSA:3.40.1010.10 2 114 8.9E-21 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 UA74_09160 771b590aad906bb88715b188e149d372 462 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 213 1.7E-35 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 UA74_15530 725df0bb693207a6b7c68b8a2df773ef 256 Pfam PF02525 Flavodoxin-like fold 1 214 1.9E-54 T 12-10-2018 IPR003680 Flavodoxin-like fold UA74_15530 725df0bb693207a6b7c68b8a2df773ef 256 SUPERFAMILY SSF52218 1 235 2.79E-66 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_15530 725df0bb693207a6b7c68b8a2df773ef 256 Gene3D G3DSA:3.40.50.360 1 255 7.6E-88 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 SUPERFAMILY SSF56235 6 599 4.05E-127 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 Pfam PF01019 Gamma-glutamyltranspeptidase 35 592 8.0E-129 T 12-10-2018 UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 Gene3D G3DSA:3.60.20.40 409 599 1.4E-45 T 12-10-2018 UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 Gene3D G3DSA:1.10.246.130 269 382 2.9E-22 T 12-10-2018 UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 8.7E-27 T 12-10-2018 UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 487 504 8.7E-27 T 12-10-2018 UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 409 427 8.7E-27 T 12-10-2018 UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 463 478 8.7E-27 T 12-10-2018 UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 8.7E-27 T 12-10-2018 UA74_20135 835d1e556ddfab7707fee6dbbd10157e 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 42 67 8.7E-27 T 12-10-2018 UA74_07135 d5cd24b4afd8c14f18d8b8b375489fd0 558 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 44 457 5.4E-72 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UA74_07135 d5cd24b4afd8c14f18d8b8b375489fd0 558 Pfam PF00474 Sodium:solute symporter family 44 454 1.0E-47 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UA74_07135 d5cd24b4afd8c14f18d8b8b375489fd0 558 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 159 184 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site UA74_07135 d5cd24b4afd8c14f18d8b8b375489fd0 558 Gene3D G3DSA:1.20.1730.10 33 528 3.2E-110 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily UA74_03755 c4ef28508004325fbd75ea5ab0cf36c5 492 Pfam PF00450 Serine carboxypeptidase 82 214 3.6E-9 T 12-10-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 UA74_03755 c4ef28508004325fbd75ea5ab0cf36c5 492 Gene3D G3DSA:3.40.50.1820 29 234 8.1E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_03755 c4ef28508004325fbd75ea5ab0cf36c5 492 SUPERFAMILY SSF53474 34 480 1.64E-71 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_00400 0dda86806b22ad4856f7714b51220185 266 SUPERFAMILY SSF53335 10 244 1.79E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_00400 0dda86806b22ad4856f7714b51220185 266 Pfam PF04672 S-adenosyl methyltransferase 10 265 1.3E-82 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_00400 0dda86806b22ad4856f7714b51220185 266 Gene3D G3DSA:3.40.50.150 2 265 1.1E-93 T 12-10-2018 UA74_00400 0dda86806b22ad4856f7714b51220185 266 PIRSF PIRSF017393 2 266 5.9E-85 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_14220 feb12c35303c160344162111e139c347 453 Pfam PF02447 GntP family permease 6 445 2.1E-80 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_20205 0deee83436bf4d9e55c7873e2f089ba7 282 SMART SM00530 14 69 5.5E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_20205 0deee83436bf4d9e55c7873e2f089ba7 282 Gene3D G3DSA:1.10.260.40 4 68 1.0E-12 T 12-10-2018 UA74_20205 0deee83436bf4d9e55c7873e2f089ba7 282 Pfam PF13560 Helix-turn-helix domain 10 72 3.1E-12 T 12-10-2018 UA74_20205 0deee83436bf4d9e55c7873e2f089ba7 282 SUPERFAMILY SSF47413 10 65 2.82E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_14585 79a0c394c5626c1da72a375a9483d569 226 Pfam PF12833 Helix-turn-helix domain 149 225 4.5E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_14585 79a0c394c5626c1da72a375a9483d569 226 Gene3D G3DSA:1.10.10.60 130 226 6.5E-20 T 12-10-2018 UA74_14585 79a0c394c5626c1da72a375a9483d569 226 SMART SM00342 141 223 3.7E-13 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_14830 b059d7079ea6fc8fc0a460f2e1c675c4 191 SUPERFAMILY SSF55729 14 182 3.73E-43 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_14830 b059d7079ea6fc8fc0a460f2e1c675c4 191 Pfam PF13302 Acetyltransferase (GNAT) domain 20 158 6.9E-32 T 12-10-2018 IPR000182 GNAT domain UA74_14830 b059d7079ea6fc8fc0a460f2e1c675c4 191 Gene3D G3DSA:3.40.630.30 12 191 3.9E-48 T 12-10-2018 UA74_21345 ea498484edd7f847a6d130bbd846253d 328 SUPERFAMILY SSF53807 65 321 8.24E-52 T 12-10-2018 UA74_21345 ea498484edd7f847a6d130bbd846253d 328 Gene3D G3DSA:3.40.50.1980 191 321 2.9E-30 T 12-10-2018 UA74_21345 ea498484edd7f847a6d130bbd846253d 328 Pfam PF01497 Periplasmic binding protein 77 301 2.4E-25 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_21345 ea498484edd7f847a6d130bbd846253d 328 Gene3D G3DSA:3.40.50.1980 65 189 2.0E-26 T 12-10-2018 UA74_10955 4303fdf1e2c620d1c2d0a93d207fed16 472 Gene3D G3DSA:1.20.1720.10 22 205 2.8E-36 T 12-10-2018 UA74_10955 4303fdf1e2c620d1c2d0a93d207fed16 472 SUPERFAMILY SSF103473 10 464 2.09E-56 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_10955 4303fdf1e2c620d1c2d0a93d207fed16 472 Gene3D G3DSA:1.20.1250.20 267 463 1.4E-18 T 12-10-2018 UA74_10955 4303fdf1e2c620d1c2d0a93d207fed16 472 Pfam PF07690 Major Facilitator Superfamily 26 417 1.7E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_16865 1b5b1b576a6781c5dc6c2d113aad19dd 522 Pfam PF04820 Tryptophan halogenase 5 480 4.5E-145 T 12-10-2018 IPR006905 Flavin-dependent halogenase UA74_16865 1b5b1b576a6781c5dc6c2d113aad19dd 522 PIRSF PIRSF011396 1 519 3.5E-153 T 12-10-2018 IPR033856 Flavin-dependent tryptophan halogenase UA74_16865 1b5b1b576a6781c5dc6c2d113aad19dd 522 SUPERFAMILY SSF51905 3 423 2.3E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16865 1b5b1b576a6781c5dc6c2d113aad19dd 522 Gene3D G3DSA:3.50.50.60 1 518 5.3E-213 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_03220 0451ce426e83879ca3f9a813736f38b8 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 227 2.7E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_03220 0451ce426e83879ca3f9a813736f38b8 232 Gene3D G3DSA:3.40.50.2300 1 125 5.1E-41 T 12-10-2018 UA74_03220 0451ce426e83879ca3f9a813736f38b8 232 SUPERFAMILY SSF52172 1 186 5.69E-44 T 12-10-2018 IPR011006 CheY-like superfamily UA74_03220 0451ce426e83879ca3f9a813736f38b8 232 SMART SM00862 152 227 5.5E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_03220 0451ce426e83879ca3f9a813736f38b8 232 Gene3D G3DSA:1.10.10.10 132 231 2.1E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_03220 0451ce426e83879ca3f9a813736f38b8 232 SMART SM00448 1 112 2.4E-46 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_03220 0451ce426e83879ca3f9a813736f38b8 232 Pfam PF00072 Response regulator receiver domain 3 112 3.8E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_08815 0e23449b4c57046b00bd84eba33f4863 463 Pfam PF02517 CAAX protease self-immunity 367 453 4.9E-12 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 SMART SM00421 137 194 2.4E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 1.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 1.7E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 1.7E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 1.7E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 SUPERFAMILY SSF52172 1 129 2.85E-29 T 12-10-2018 IPR011006 CheY-like superfamily UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 Gene3D G3DSA:3.40.50.12740 3 200 1.9E-50 T 12-10-2018 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 SMART SM00448 2 115 3.8E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 SUPERFAMILY SSF46894 131 200 2.72E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_05435 d907137e722c0b21dcbe1aff39589d1c 200 Pfam PF00072 Response regulator receiver domain 4 114 3.0E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_17650 0c145630b7fced9cfd907e32437c2403 331 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 15 275 5.5E-70 T 12-10-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 UA74_17650 0c145630b7fced9cfd907e32437c2403 331 Gene3D G3DSA:3.40.50.150 6 296 1.9E-68 T 12-10-2018 UA74_17650 0c145630b7fced9cfd907e32437c2403 331 SUPERFAMILY SSF53335 14 293 1.58E-60 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_17650 0c145630b7fced9cfd907e32437c2403 331 Pfam PF04072 Leucine carboxyl methyltransferase 18 197 4.5E-52 T 12-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 UA74_04815 aa51c09717fac01636a8511f63e5bd1c 456 SUPERFAMILY SSF63411 39 242 1.56E-25 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_04815 aa51c09717fac01636a8511f63e5bd1c 456 Pfam PF05193 Peptidase M16 inactive domain 205 371 6.1E-14 T 12-10-2018 IPR007863 Peptidase M16, C-terminal UA74_04815 aa51c09717fac01636a8511f63e5bd1c 456 Gene3D G3DSA:3.30.830.10 252 443 9.2E-42 T 12-10-2018 UA74_04815 aa51c09717fac01636a8511f63e5bd1c 456 SUPERFAMILY SSF63411 260 451 1.13E-33 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UA74_04815 aa51c09717fac01636a8511f63e5bd1c 456 Gene3D G3DSA:3.30.830.10 39 243 6.3E-27 T 12-10-2018 UA74_04815 aa51c09717fac01636a8511f63e5bd1c 456 Pfam PF00675 Insulinase (Peptidase family M16) 73 185 4.2E-5 T 12-10-2018 IPR011765 Peptidase M16, N-terminal UA74_28130 4f392d01fabc1ba38d4d31223b4aea1a 267 PIRSF PIRSF017393 1 264 2.9E-77 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_28130 4f392d01fabc1ba38d4d31223b4aea1a 267 Gene3D G3DSA:3.40.50.150 1 266 1.1E-84 T 12-10-2018 UA74_28130 4f392d01fabc1ba38d4d31223b4aea1a 267 Pfam PF04672 S-adenosyl methyltransferase 12 252 8.2E-70 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_28130 4f392d01fabc1ba38d4d31223b4aea1a 267 SUPERFAMILY SSF53335 16 250 7.07E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_01685 886670f7a5dc2d3420b423e4d979dd14 232 Gene3D G3DSA:3.40.50.1000 1 223 1.4E-26 T 12-10-2018 IPR023214 HAD superfamily UA74_01685 886670f7a5dc2d3420b423e4d979dd14 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 9.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_01685 886670f7a5dc2d3420b423e4d979dd14 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 168 188 9.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_01685 886670f7a5dc2d3420b423e4d979dd14 232 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 120 133 9.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_01685 886670f7a5dc2d3420b423e4d979dd14 232 SUPERFAMILY SSF56784 4 210 3.16E-29 T 12-10-2018 IPR036412 HAD-like superfamily UA74_01685 886670f7a5dc2d3420b423e4d979dd14 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 103 203 2.4E-10 T 12-10-2018 UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 Pfam PF00732 GMC oxidoreductase 2 299 2.1E-67 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 259 273 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 SUPERFAMILY SSF54373 350 452 1.86E-12 T 12-10-2018 UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 Pfam PF05199 GMC oxidoreductase 362 504 6.0E-35 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 Gene3D G3DSA:3.50.50.60 2 505 3.8E-153 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 SUPERFAMILY SSF51905 2 509 4.15E-66 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 85 108 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 PIRSF PIRSF000137 353 514 1.7E-34 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 PIRSF PIRSF000137 1 319 1.2E-71 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_05360 fcfed36770daef9a18a8666a2170cc6e 514 Gene3D G3DSA:3.30.410.40 153 446 3.8E-153 T 12-10-2018 UA74_00575 98751b10106064f7ffe9a20c0b5c4820 178 Pfam PF00011 Hsp20/alpha crystallin family 52 150 1.9E-15 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain UA74_00575 98751b10106064f7ffe9a20c0b5c4820 178 Gene3D G3DSA:2.60.40.790 1 151 4.3E-27 T 12-10-2018 IPR008978 HSP20-like chaperone UA74_00575 98751b10106064f7ffe9a20c0b5c4820 178 SUPERFAMILY SSF49764 30 149 5.58E-27 T 12-10-2018 IPR008978 HSP20-like chaperone UA74_17230 36143297917e7fc749411f14fa40c651 240 Pfam PF16715 Cyclodipeptide synthase 24 223 6.1E-44 T 12-10-2018 IPR030903 Cyclodipeptide synthase GO:0016755 UA74_17230 36143297917e7fc749411f14fa40c651 240 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 32 223 3.9E-48 T 12-10-2018 IPR030903 Cyclodipeptide synthase GO:0016755 UA74_17230 36143297917e7fc749411f14fa40c651 240 Gene3D G3DSA:3.40.50.11710 25 236 1.9E-55 T 12-10-2018 IPR038622 Cyclodipeptide synthase superfamily GO:0016755 UA74_28940 60e0e5dd64abfa401a7353bdd823691e 207 Pfam PF13563 2'-5' RNA ligase superfamily 59 187 1.5E-20 T 12-10-2018 UA74_28940 60e0e5dd64abfa401a7353bdd823691e 207 SUPERFAMILY SSF55144 38 204 3.92E-15 T 12-10-2018 IPR009097 Cyclic phosphodiesterase UA74_28940 60e0e5dd64abfa401a7353bdd823691e 207 Gene3D G3DSA:3.90.1140.10 38 205 9.3E-21 T 12-10-2018 UA74_15590 d16e2754bbe01343321956926973e46a 155 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 6 13 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_15590 d16e2754bbe01343321956926973e46a 155 Pfam PF00484 Carbonic anhydrase 2 151 1.5E-35 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_15590 d16e2754bbe01343321956926973e46a 155 Gene3D G3DSA:3.40.1050.10 1 155 4.4E-47 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UA74_15590 d16e2754bbe01343321956926973e46a 155 SMART SM00947 1 155 8.1E-33 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UA74_15590 d16e2754bbe01343321956926973e46a 155 SUPERFAMILY SSF53056 2 155 6.02E-39 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UA74_21900 6878921e5c416952e51f562fd7884b21 135 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 12 127 3.3E-30 T 12-10-2018 IPR019920 F420-binding domain, putative UA74_21900 6878921e5c416952e51f562fd7884b21 135 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 91 6.4E-14 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_21900 6878921e5c416952e51f562fd7884b21 135 Gene3D G3DSA:2.30.110.10 4 127 9.5E-29 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_21900 6878921e5c416952e51f562fd7884b21 135 SUPERFAMILY SSF50475 6 130 2.06E-28 T 12-10-2018 UA74_22115 10e6e2c2e2b544de8e39b2992353e292 449 Gene3D G3DSA:3.40.50.720 6 152 2.6E-21 T 12-10-2018 UA74_22115 10e6e2c2e2b544de8e39b2992353e292 449 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 162 242 1.6E-17 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UA74_22115 10e6e2c2e2b544de8e39b2992353e292 449 SUPERFAMILY SSF51735 48 181 2.4E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22115 10e6e2c2e2b544de8e39b2992353e292 449 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 42 150 2.6E-18 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_22115 10e6e2c2e2b544de8e39b2992353e292 449 SUPERFAMILY SSF55347 158 353 3.27E-23 T 12-10-2018 UA74_00465 4723f8e4d5eba411e11be525e651727e 321 SUPERFAMILY SSF103642 21 39 1.8E-5 T 12-10-2018 UA74_29055 42fea3d9593f4d5ceb3db4d7f8c89f0a 135 Gene3D G3DSA:2.60.40.200 7 133 1.4E-13 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_29055 42fea3d9593f4d5ceb3db4d7f8c89f0a 135 SUPERFAMILY SSF49329 15 132 8.77E-14 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_29055 42fea3d9593f4d5ceb3db4d7f8c89f0a 135 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 18 131 3.7E-8 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UA74_09425 9c1d98791cb0db8dcab09461f3137bd8 198 Pfam PF00583 Acetyltransferase (GNAT) family 50 154 6.4E-5 T 12-10-2018 IPR000182 GNAT domain UA74_09425 9c1d98791cb0db8dcab09461f3137bd8 198 Gene3D G3DSA:3.40.630.30 5 178 1.1E-29 T 12-10-2018 UA74_09425 9c1d98791cb0db8dcab09461f3137bd8 198 SUPERFAMILY SSF55729 5 163 8.29E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_22890 1b409296b25c5f413e6e3d42c0c90214 192 Gene3D G3DSA:1.10.340.30 18 141 5.6E-8 T 12-10-2018 UA74_22890 1b409296b25c5f413e6e3d42c0c90214 192 SUPERFAMILY SSF48150 18 148 2.27E-15 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UA74_22890 1b409296b25c5f413e6e3d42c0c90214 192 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 4 190 7.8E-91 T 12-10-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD UA74_22890 1b409296b25c5f413e6e3d42c0c90214 192 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 27 185 5.9E-16 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 Pfam PF00005 ABC transporter 354 504 5.9E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 SUPERFAMILY SSF52540 3 287 1.95E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 SMART SM00382 362 553 8.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 SMART SM00382 32 244 2.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 ProSitePatterns PS00211 ABC transporters family signature. 184 198 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 Gene3D G3DSA:3.40.50.300 330 593 2.3E-74 T 12-10-2018 UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 SUPERFAMILY SSF52540 333 575 2.39E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 555 587 1.2E-4 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 263 295 0.0012 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_13950 d791637d7a51cc48ccc1b02d2c645b0a 688 Pfam PF00005 ABC transporter 24 211 8.2E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_20390 787f316dd82b4762398da463e7eeabab 220 Pfam PF01323 DSBA-like thioredoxin domain 12 212 3.4E-44 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 UA74_20390 787f316dd82b4762398da463e7eeabab 220 Gene3D G3DSA:3.40.30.10 5 216 1.5E-73 T 12-10-2018 UA74_20390 787f316dd82b4762398da463e7eeabab 220 SUPERFAMILY SSF52833 10 218 2.86E-50 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_12340 eb5a85640ceff92c732a237655e3e516 356 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 22 294 1.0E-84 T 12-10-2018 IPR010119 Gluconeogenesis factor UA74_12340 eb5a85640ceff92c732a237655e3e516 356 Gene3D G3DSA:3.40.50.12300 17 333 2.1E-92 T 12-10-2018 IPR038136 Gluconeogenesis factor superfamily UA74_12340 eb5a85640ceff92c732a237655e3e516 356 Hamap MF_00973 Gluconeogenesis factor. 17 332 32.035 T 12-10-2018 IPR010119 Gluconeogenesis factor UA74_12340 eb5a85640ceff92c732a237655e3e516 356 SUPERFAMILY SSF142338 19 327 5.49E-81 T 12-10-2018 UA74_12340 eb5a85640ceff92c732a237655e3e516 356 Pfam PF01933 Uncharacterised protein family UPF0052 22 288 5.3E-67 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 UA74_05885 6227d5cb488a4b621b664d686c011a5c 640 Gene3D G3DSA:3.30.2010.10 72 164 1.2E-5 T 12-10-2018 UA74_05885 6227d5cb488a4b621b664d686c011a5c 640 Pfam PF01435 Peptidase family M48 77 304 5.6E-15 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 UA74_22090 1b6c353ca65c09f5e8b06d7547fde378 518 Pfam PF13810 Domain of unknown function (DUF4185) 58 361 1.3E-103 T 12-10-2018 IPR025442 Domain of unknown function DUF4185 UA74_22090 1b6c353ca65c09f5e8b06d7547fde378 518 Gene3D G3DSA:2.60.120.260 370 515 6.5E-15 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_06110 c01fabe08f31e53b08cb458e77104696 395 Pfam PF13449 Esterase-like activity of phytase 50 381 7.8E-67 T 12-10-2018 IPR027372 Phytase-like domain UA74_19965 234590708698f99d83d8715b9364e4db 460 SUPERFAMILY SSF103473 14 439 5.36E-77 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_19965 234590708698f99d83d8715b9364e4db 460 Gene3D G3DSA:1.20.1250.20 4 444 1.7E-73 T 12-10-2018 UA74_19965 234590708698f99d83d8715b9364e4db 460 Pfam PF07690 Major Facilitator Superfamily 30 402 3.0E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_16810 b4a40c64af3545d3335b7b038e62b2c3 122 SUPERFAMILY SSF54427 3 115 2.87E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_16810 b4a40c64af3545d3335b7b038e62b2c3 122 Gene3D G3DSA:3.10.450.50 2 116 4.2E-13 T 12-10-2018 UA74_16810 b4a40c64af3545d3335b7b038e62b2c3 122 Pfam PF12680 SnoaL-like domain 11 109 2.5E-9 T 12-10-2018 IPR037401 SnoaL-like domain UA74_26810 b572f9aa5005bab73793f1a7d24139d6 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 221 1.0E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_26810 b572f9aa5005bab73793f1a7d24139d6 224 Gene3D G3DSA:3.40.50.2300 1 120 1.3E-37 T 12-10-2018 UA74_26810 b572f9aa5005bab73793f1a7d24139d6 224 Pfam PF00072 Response regulator receiver domain 4 114 2.0E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_26810 b572f9aa5005bab73793f1a7d24139d6 224 Gene3D G3DSA:1.10.10.10 121 224 6.4E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26810 b572f9aa5005bab73793f1a7d24139d6 224 SUPERFAMILY SSF52172 4 122 3.84E-40 T 12-10-2018 IPR011006 CheY-like superfamily UA74_26810 b572f9aa5005bab73793f1a7d24139d6 224 SMART SM00448 2 113 3.3E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_26810 b572f9aa5005bab73793f1a7d24139d6 224 SMART SM00862 143 221 1.5E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_26810 b572f9aa5005bab73793f1a7d24139d6 224 SUPERFAMILY SSF46894 124 223 1.42E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_02515 c92ad52381f5a5ba12840f09b9bb293c 326 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 16 304 1.2E-147 T 12-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 UA74_02515 c92ad52381f5a5ba12840f09b9bb293c 326 Gene3D G3DSA:1.20.1260.10 9 318 9.0E-127 T 12-10-2018 IPR012347 Ferritin-like UA74_02515 c92ad52381f5a5ba12840f09b9bb293c 326 Pfam PF05138 Phenylacetic acid catabolic protein 26 300 1.4E-96 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UA74_02515 c92ad52381f5a5ba12840f09b9bb293c 326 SUPERFAMILY SSF47240 36 279 3.24E-77 T 12-10-2018 IPR009078 Ferritin-like superfamily UA74_24870 d274ba1b8957215dafbed221b7087d3e 603 Pfam PF00501 AMP-binding enzyme 24 472 1.6E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_24870 d274ba1b8957215dafbed221b7087d3e 603 Gene3D G3DSA:3.40.50.12780 329 470 3.2E-38 T 12-10-2018 UA74_24870 d274ba1b8957215dafbed221b7087d3e 603 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_24870 d274ba1b8957215dafbed221b7087d3e 603 Gene3D G3DSA:3.40.50.12780 3 328 7.9E-50 T 12-10-2018 UA74_24870 d274ba1b8957215dafbed221b7087d3e 603 SUPERFAMILY SSF56801 17 593 2.35E-111 T 12-10-2018 UA74_22995 9844f9a89a573a94da27b9e389e8651e 165 SUPERFAMILY SSF55811 8 152 2.57E-27 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_22995 9844f9a89a573a94da27b9e389e8651e 165 Gene3D G3DSA:3.90.79.10 3 154 4.1E-28 T 12-10-2018 UA74_22995 9844f9a89a573a94da27b9e389e8651e 165 ProSitePatterns PS00893 Nudix box signature. 46 67 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_22995 9844f9a89a573a94da27b9e389e8651e 165 PRINTS PR00502 NUDIX hydrolase family signature 55 70 1.9E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_22995 9844f9a89a573a94da27b9e389e8651e 165 PRINTS PR00502 NUDIX hydrolase family signature 41 55 1.9E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_22995 9844f9a89a573a94da27b9e389e8651e 165 Pfam PF00293 NUDIX domain 11 136 1.2E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_28570 6b7efe7b0ee423a7d458878be201468a 88 Pfam PF04226 Transglycosylase associated protein 36 85 3.0E-7 T 12-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 UA74_10150 69b3ec74a6a3227876e9e55b48ca7634 331 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 170 195 - T 12-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 UA74_10150 69b3ec74a6a3227876e9e55b48ca7634 331 Pfam PF00494 Squalene/phytoene synthase 29 285 1.2E-58 T 12-10-2018 UA74_10150 69b3ec74a6a3227876e9e55b48ca7634 331 SUPERFAMILY SSF48576 18 300 7.19E-71 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_10150 69b3ec74a6a3227876e9e55b48ca7634 331 Gene3D G3DSA:1.10.600.10 9 298 1.5E-84 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily UA74_18685 cc7a43948d567c54123c2358d92199d1 706 Gene3D G3DSA:2.130.10.10 485 705 1.3E-7 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_18685 cc7a43948d567c54123c2358d92199d1 706 Gene3D G3DSA:2.130.10.10 180 484 7.9E-14 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_18685 cc7a43948d567c54123c2358d92199d1 706 SUPERFAMILY SSF82171 278 688 1.37E-13 T 12-10-2018 UA74_18685 cc7a43948d567c54123c2358d92199d1 706 SUPERFAMILY SSF101898 74 330 5.75E-16 T 12-10-2018 UA74_18685 cc7a43948d567c54123c2358d92199d1 706 Pfam PF13360 PQQ-like domain 281 462 2.2E-7 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat UA74_19980 489acd95797fe7260264d617be762f98 267 Pfam PF00121 Triosephosphate isomerase 12 247 8.2E-46 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_19980 489acd95797fe7260264d617be762f98 267 SUPERFAMILY SSF51351 10 254 1.01E-53 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UA74_19980 489acd95797fe7260264d617be762f98 267 Gene3D G3DSA:3.20.20.70 5 259 2.2E-70 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_08480 31a3b3b123b738f0f06bb2f68291a03d 266 Pfam PF11361 Protein of unknown function (DUF3159) 38 220 5.7E-65 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 UA74_08480 31a3b3b123b738f0f06bb2f68291a03d 266 PIRSF PIRSF010219 12 238 7.4E-74 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 UA74_24255 3975f642aff47e87fa2ccbfe4a365208 571 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 415 502 1.3E-5 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_24255 3975f642aff47e87fa2ccbfe4a365208 571 Gene3D G3DSA:3.40.50.1820 23 262 3.7E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24255 3975f642aff47e87fa2ccbfe4a365208 571 SMART SM00939 357 526 2.5E-10 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 UA74_24255 3975f642aff47e87fa2ccbfe4a365208 571 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 67 334 2.1E-51 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 UA74_24255 3975f642aff47e87fa2ccbfe4a365208 571 Gene3D G3DSA:3.40.50.1820 272 412 1.1E-17 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24255 3975f642aff47e87fa2ccbfe4a365208 571 SUPERFAMILY SSF53474 61 391 5.56E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24255 3975f642aff47e87fa2ccbfe4a365208 571 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 71 413 3.1E-81 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 UA74_24255 3975f642aff47e87fa2ccbfe4a365208 571 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 419 525 7.6E-20 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 UA74_24255 3975f642aff47e87fa2ccbfe4a365208 571 SUPERFAMILY SSF49785 352 502 6.16E-14 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily UA74_29450 7ce22de00337cad786f37447b3e0e198 206 SUPERFAMILY SSF55961 8 142 2.36E-15 T 12-10-2018 UA74_29450 7ce22de00337cad786f37447b3e0e198 206 Gene3D G3DSA:3.30.530.20 9 149 6.3E-10 T 12-10-2018 IPR023393 START-like domain superfamily UA74_17920 60829684dc59117409cdba8d8551fb72 364 SUPERFAMILY SSF48403 62 150 2.18E-13 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily UA74_17920 60829684dc59117409cdba8d8551fb72 364 Pfam PF12796 Ankyrin repeats (3 copies) 71 141 2.9E-8 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain UA74_17920 60829684dc59117409cdba8d8551fb72 364 SMART SM00248 81 110 0.55 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_17920 60829684dc59117409cdba8d8551fb72 364 SMART SM00248 113 144 24.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 UA74_17920 60829684dc59117409cdba8d8551fb72 364 Gene3D G3DSA:1.25.40.20 58 158 3.2E-16 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily UA74_06875 f16252cfd8cdbec9a41c49f333bd6170 432 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 20 398 4.4E-104 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 UA74_06875 f16252cfd8cdbec9a41c49f333bd6170 432 Gene3D G3DSA:1.20.1720.10 23 403 1.8E-107 T 12-10-2018 UA74_06875 f16252cfd8cdbec9a41c49f333bd6170 432 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_06875 f16252cfd8cdbec9a41c49f333bd6170 432 Pfam PF07690 Major Facilitator Superfamily 30 371 3.5E-47 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_06875 f16252cfd8cdbec9a41c49f333bd6170 432 SUPERFAMILY SSF103473 12 412 9.02E-69 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_06875 f16252cfd8cdbec9a41c49f333bd6170 432 PRINTS PR01035 Tetracycline resistance protein signature 117 138 2.5E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_06875 f16252cfd8cdbec9a41c49f333bd6170 432 PRINTS PR01035 Tetracycline resistance protein signature 90 114 2.5E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_06875 f16252cfd8cdbec9a41c49f333bd6170 432 PRINTS PR01035 Tetracycline resistance protein signature 33 49 2.5E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_06875 f16252cfd8cdbec9a41c49f333bd6170 432 PRINTS PR01035 Tetracycline resistance protein signature 290 311 2.5E-6 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UA74_14415 139f4356423e7aee57b4afd4c2500d9a 206 Pfam PF01300 Telomere recombination 23 198 2.0E-39 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 UA74_14415 139f4356423e7aee57b4afd4c2500d9a 206 Gene3D G3DSA:3.90.870.10 1 206 4.2E-57 T 12-10-2018 UA74_14415 139f4356423e7aee57b4afd4c2500d9a 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 8.7E-53 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 UA74_14415 139f4356423e7aee57b4afd4c2500d9a 206 SUPERFAMILY SSF55821 1 204 4.88E-57 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily UA74_10610 23c7d070c17beb528052252b9e9a5311 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 319 1.1E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_20750 6a6e52d91e6108414fd648cbe827090a 120 Gene3D G3DSA:2.60.200.60 28 117 3.3E-12 T 12-10-2018 UA74_20750 6a6e52d91e6108414fd648cbe827090a 120 Pfam PF05488 PAAR motif 80 119 1.0E-7 T 12-10-2018 IPR008727 PAAR motif UA74_12315 46842fe0f26b7a81bd6a64a2820af3e3 164 SUPERFAMILY SSF52121 13 157 1.44E-49 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12315 46842fe0f26b7a81bd6a64a2820af3e3 164 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 16 152 2.8E-48 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12315 46842fe0f26b7a81bd6a64a2820af3e3 164 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 155 26.005 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12315 46842fe0f26b7a81bd6a64a2820af3e3 164 Gene3D G3DSA:3.40.50.960 1 159 2.4E-54 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_12315 46842fe0f26b7a81bd6a64a2820af3e3 164 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 150 8.9E-38 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UA74_03785 791c5bab6a562efb318296744895350d 333 Gene3D G3DSA:3.40.50.300 31 197 2.2E-45 T 12-10-2018 UA74_03785 791c5bab6a562efb318296744895350d 333 SMART SM00382 47 188 0.0015 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_03785 791c5bab6a562efb318296744895350d 333 PIRSF PIRSF002849 4 325 3.9E-124 T 12-10-2018 UA74_03785 791c5bab6a562efb318296744895350d 333 SUPERFAMILY SSF52540 30 296 1.61E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_03785 791c5bab6a562efb318296744895350d 333 Gene3D G3DSA:1.10.8.300 212 320 4.4E-30 T 12-10-2018 UA74_03785 791c5bab6a562efb318296744895350d 333 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 50 180 1.2E-62 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 UA74_29245 067d9ff1b2c9091625d4fc5573fa93b3 285 Gene3D G3DSA:3.20.20.80 77 285 7.2E-85 T 12-10-2018 UA74_29245 067d9ff1b2c9091625d4fc5573fa93b3 285 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 84 117 - T 12-10-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 UA74_29245 067d9ff1b2c9091625d4fc5573fa93b3 285 Pfam PF01183 Glycosyl hydrolases family 25 83 267 2.4E-49 T 12-10-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 UA74_29245 067d9ff1b2c9091625d4fc5573fa93b3 285 SUPERFAMILY SSF51445 78 284 2.95E-63 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_29245 067d9ff1b2c9091625d4fc5573fa93b3 285 SMART SM00641 80 189 1.2E-44 T 12-10-2018 IPR018077 Glycoside hydrolase, family 25 subgroup UA74_07610 92c2f9f279d0d8fdcf3a9d19804bcb04 204 Gene3D G3DSA:1.10.10.60 2 64 6.2E-13 T 12-10-2018 UA74_07610 92c2f9f279d0d8fdcf3a9d19804bcb04 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 68 6.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_07610 92c2f9f279d0d8fdcf3a9d19804bcb04 204 Gene3D G3DSA:1.10.357.10 65 202 8.0E-18 T 12-10-2018 UA74_07610 92c2f9f279d0d8fdcf3a9d19804bcb04 204 SUPERFAMILY SSF48498 89 198 2.33E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_07610 92c2f9f279d0d8fdcf3a9d19804bcb04 204 SUPERFAMILY SSF46689 14 93 7.18E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_21160 bcafd72ea52d414488ddbd432219b687 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.281 T 12-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid UA74_21160 bcafd72ea52d414488ddbd432219b687 101 SUPERFAMILY SSF57716 2 101 1.21E-34 T 12-10-2018 UA74_21160 bcafd72ea52d414488ddbd432219b687 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 9.7E-26 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21160 bcafd72ea52d414488ddbd432219b687 101 Gene3D G3DSA:4.10.830.10 39 101 1.8E-24 T 12-10-2018 UA74_24050 cabcd2c9b34f51be6c89e47fee2aded8 159 Gene3D G3DSA:1.10.10.10 43 157 4.6E-43 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24050 cabcd2c9b34f51be6c89e47fee2aded8 159 Pfam PF01638 HxlR-like helix-turn-helix 59 145 2.8E-28 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_24050 cabcd2c9b34f51be6c89e47fee2aded8 159 SUPERFAMILY SSF46785 47 153 2.82E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_01755 e23a514425482bb31517e598a0ae4d1b 283 SUPERFAMILY SSF81345 10 268 1.31E-31 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_01755 e23a514425482bb31517e598a0ae4d1b 283 Pfam PF00950 ABC 3 transport family 17 269 1.2E-42 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UA74_00615 7b6500cd3b38bc3d289dcb9a692e0838 156 Pfam PF03994 Domain of Unknown Function (DUF350) 101 155 1.7E-9 T 12-10-2018 IPR007140 Protein of unknown function DUF350 UA74_00615 7b6500cd3b38bc3d289dcb9a692e0838 156 Pfam PF03994 Domain of Unknown Function (DUF350) 31 84 1.0E-14 T 12-10-2018 IPR007140 Protein of unknown function DUF350 UA74_05760 f1e7b9cbcef49e5b840241a4127ae25b 286 Gene3D G3DSA:3.10.450.50 2 133 1.3E-18 T 12-10-2018 UA74_05760 f1e7b9cbcef49e5b840241a4127ae25b 286 Pfam PF07366 SnoaL-like polyketide cyclase 5 105 8.9E-13 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 UA74_05760 f1e7b9cbcef49e5b840241a4127ae25b 286 SUPERFAMILY SSF54427 3 126 3.09E-15 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_17665 947c5bc941c4aa910379af7639a192b7 589 Gene3D G3DSA:2.120.10.30 128 331 1.4E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_17665 947c5bc941c4aa910379af7639a192b7 589 SUPERFAMILY SSF82171 24 307 2.22E-23 T 12-10-2018 UA74_17665 947c5bc941c4aa910379af7639a192b7 589 Pfam PF00326 Prolyl oligopeptidase family 373 578 8.7E-34 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UA74_17665 947c5bc941c4aa910379af7639a192b7 589 Gene3D G3DSA:3.40.50.1820 332 583 1.9E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17665 947c5bc941c4aa910379af7639a192b7 589 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 378 402 3.8E-6 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_17665 947c5bc941c4aa910379af7639a192b7 589 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 438 458 3.8E-6 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_17665 947c5bc941c4aa910379af7639a192b7 589 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 352 370 3.8E-6 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_17665 947c5bc941c4aa910379af7639a192b7 589 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 512 534 3.8E-6 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 UA74_17665 947c5bc941c4aa910379af7639a192b7 589 SUPERFAMILY SSF53474 278 582 1.17E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_11460 ed716653a9857243fbb900cf57ef0d1c 256 Pfam PF07510 Protein of unknown function (DUF1524) 151 249 3.8E-8 T 12-10-2018 IPR011089 Domain of unknown function DUF1524 UA74_09735 185860ab6ef69de3c74d8f306330703e 309 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 136 150 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_09735 185860ab6ef69de3c74d8f306330703e 309 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 306 3.6E-84 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_09735 185860ab6ef69de3c74d8f306330703e 309 Gene3D G3DSA:3.10.290.10 4 66 3.4E-7 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UA74_09735 185860ab6ef69de3c74d8f306330703e 309 Gene3D G3DSA:3.30.2350.10 83 309 1.3E-69 T 12-10-2018 UA74_09735 185860ab6ef69de3c74d8f306330703e 309 Pfam PF00849 RNA pseudouridylate synthase 91 244 4.1E-33 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_09735 185860ab6ef69de3c74d8f306330703e 309 SUPERFAMILY SSF55120 77 306 2.24E-69 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_27935 494210571bbf7217682bb0c1ef133caf 175 Gene3D G3DSA:2.60.40.380 38 148 2.8E-33 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 UA74_27935 494210571bbf7217682bb0c1ef133caf 175 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 46 142 2.0E-30 T 12-10-2018 IPR032093 Phospholipase D, N-terminal UA74_14190 86c43a34a57073290fedb41a67ff3718 404 Gene3D G3DSA:3.40.190.10 123 396 1.2E-113 T 12-10-2018 UA74_14190 86c43a34a57073290fedb41a67ff3718 404 Gene3D G3DSA:3.40.190.10 13 351 1.2E-113 T 12-10-2018 UA74_14190 86c43a34a57073290fedb41a67ff3718 404 SUPERFAMILY SSF53850 5 403 1.4E-52 T 12-10-2018 UA74_14190 86c43a34a57073290fedb41a67ff3718 404 Pfam PF01547 Bacterial extracellular solute-binding protein 27 312 4.5E-24 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_18415 14f3822240f8e06a02b17229afa183bc 258 SUPERFAMILY SSF53474 2 256 1.4E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18415 14f3822240f8e06a02b17229afa183bc 258 Gene3D G3DSA:3.40.50.1820 1 257 3.3E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18415 14f3822240f8e06a02b17229afa183bc 258 Pfam PF12697 Alpha/beta hydrolase family 23 242 5.8E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_10750 843a4b1fbceb493509f5819daaae999c 246 SUPERFAMILY SSF102215 4 239 5.49E-51 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 UA74_10750 843a4b1fbceb493509f5819daaae999c 246 Pfam PF02633 Creatinine amidohydrolase 20 237 6.7E-52 T 12-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 UA74_10750 843a4b1fbceb493509f5819daaae999c 246 Gene3D G3DSA:3.40.50.10310 14 241 9.6E-59 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 UA74_02550 5e1eb52aa6a4055408d7af4a7875f828 214 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 120 134 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 UA74_02550 5e1eb52aa6a4055408d7af4a7875f828 214 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 212 30.285 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UA74_02550 5e1eb52aa6a4055408d7af4a7875f828 214 Gene3D G3DSA:3.40.50.150 4 212 1.6E-54 T 12-10-2018 UA74_02550 5e1eb52aa6a4055408d7af4a7875f828 214 SUPERFAMILY SSF53335 1 209 4.18E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_02550 5e1eb52aa6a4055408d7af4a7875f828 214 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 1 211 4.9E-63 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UA74_02550 5e1eb52aa6a4055408d7af4a7875f828 214 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 211 2.1E-51 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UA74_02875 b7376930cf7463bcf02c4ea2805a325d 82 Pfam PF04149 Domain of unknown function (DUF397) 21 76 4.0E-14 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_21800 22c3b7fa1754907ea8253f23a8217486 414 Pfam PF13527 Acetyltransferase (GNAT) domain 20 144 1.7E-15 T 12-10-2018 UA74_21800 22c3b7fa1754907ea8253f23a8217486 414 SUPERFAMILY SSF55729 17 256 3.62E-31 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_21800 22c3b7fa1754907ea8253f23a8217486 414 Gene3D G3DSA:3.40.630.30 16 146 2.3E-20 T 12-10-2018 UA74_21800 22c3b7fa1754907ea8253f23a8217486 414 Gene3D G3DSA:3.40.630.30 165 264 2.5E-6 T 12-10-2018 UA74_10400 a5a81ca153ce07ad7dab66021a072c8f 325 Gene3D G3DSA:3.90.25.10 189 310 7.2E-98 T 12-10-2018 UA74_10400 a5a81ca153ce07ad7dab66021a072c8f 325 SUPERFAMILY SSF51735 7 313 4.34E-87 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_10400 a5a81ca153ce07ad7dab66021a072c8f 325 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 305 4.6E-51 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_10400 a5a81ca153ce07ad7dab66021a072c8f 325 Gene3D G3DSA:3.40.50.720 7 297 7.2E-98 T 12-10-2018 UA74_23140 b746d2c3c2efe656b511727f9c4d2a34 523 SUPERFAMILY SSF103473 7 515 2.53E-65 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_23140 b746d2c3c2efe656b511727f9c4d2a34 523 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 430 1.8E-78 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UA74_23140 b746d2c3c2efe656b511727f9c4d2a34 523 Gene3D G3DSA:1.20.1720.10 23 256 2.8E-41 T 12-10-2018 UA74_23140 b746d2c3c2efe656b511727f9c4d2a34 523 Pfam PF07690 Major Facilitator Superfamily 27 418 3.3E-49 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_23155 20b0c6d4e4c58e00845729132f9caf76 230 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 10 203 2.4E-25 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 UA74_06735 ee2f3676783290c3212fe919037f70c6 244 Gene3D G3DSA:1.20.1260.10 64 244 3.7E-51 T 12-10-2018 IPR012347 Ferritin-like UA74_06735 ee2f3676783290c3212fe919037f70c6 244 Pfam PF03713 Domain of unknown function (DUF305) 71 241 9.5E-45 T 12-10-2018 IPR005183 Domain of unknown function DUF305 UA74_25660 0d988ff58a8c795259f16a9fe377c0e2 71 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 1 57 1.0E-15 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane UA74_12800 2e7d8435419b87fbbb7a157ecf14c189 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 11 86 2.8E-6 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 UA74_12800 2e7d8435419b87fbbb7a157ecf14c189 87 Gene3D G3DSA:1.10.287.1080 1 87 5.6E-22 T 12-10-2018 UA74_12800 2e7d8435419b87fbbb7a157ecf14c189 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 2.7E-21 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 UA74_12800 2e7d8435419b87fbbb7a157ecf14c189 87 SUPERFAMILY SSF101386 2 87 1.83E-20 T 12-10-2018 UA74_12800 2e7d8435419b87fbbb7a157ecf14c189 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 17.471 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 UA74_25305 5e53120a8daeb79ff580febebd13b96d 1401 SUPERFAMILY SSF52540 19 1349 1.29E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_25305 5e53120a8daeb79ff580febebd13b96d 1401 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1254 1347 5.1E-19 T 12-10-2018 UA74_25305 5e53120a8daeb79ff580febebd13b96d 1401 TIGRFAM TIGR02680 TIGR02680: TIGR02680 family protein 6 1395 1.9E-201 T 12-10-2018 IPR013496 Conserved hypothetical protein CHP02680 UA74_09095 8e60c988cdd67b311ac16567128a476b 427 Pfam PF07730 Histidine kinase 222 287 4.8E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_09095 8e60c988cdd67b311ac16567128a476b 427 Gene3D G3DSA:3.30.565.10 292 421 7.6E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_09095 8e60c988cdd67b311ac16567128a476b 427 SUPERFAMILY SSF55874 303 419 1.2E-8 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_23365 72ab051608fa4d0ea05c63be256a7d38 159 Gene3D G3DSA:3.30.530.20 3 153 5.5E-41 T 12-10-2018 IPR023393 START-like domain superfamily UA74_23365 72ab051608fa4d0ea05c63be256a7d38 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 148 3.8E-28 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_23365 72ab051608fa4d0ea05c63be256a7d38 159 SUPERFAMILY SSF55961 7 149 7.47E-40 T 12-10-2018 UA74_07340 c1d83b6c9f86aa445bcee7ebeb62b2ec 333 SUPERFAMILY SSF161098 87 314 5.49E-48 T 12-10-2018 IPR035906 MetI-like superfamily UA74_07340 c1d83b6c9f86aa445bcee7ebeb62b2ec 333 Gene3D G3DSA:1.10.3720.10 83 324 2.1E-55 T 12-10-2018 IPR035906 MetI-like superfamily UA74_07340 c1d83b6c9f86aa445bcee7ebeb62b2ec 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 260 1.4E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_10135 172f6330049c62f8620417b37f6bbfe8 294 Pfam PF11599 RRNA methyltransferase AviRa 9 186 1.3E-21 T 12-10-2018 IPR024268 rRNA methyltransferase AviRa UA74_10135 172f6330049c62f8620417b37f6bbfe8 294 SUPERFAMILY SSF53335 16 191 2.09E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_10135 172f6330049c62f8620417b37f6bbfe8 294 Gene3D G3DSA:3.40.50.150 225 294 4.9E-7 T 12-10-2018 UA74_29830 d0b752d17f44dcc36e11213bcc60d6eb 140 Gene3D G3DSA:3.30.720.110 70 125 2.2E-23 T 12-10-2018 UA74_29830 d0b752d17f44dcc36e11213bcc60d6eb 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 120 1.0E-5 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_29830 d0b752d17f44dcc36e11213bcc60d6eb 140 Gene3D G3DSA:3.30.720.120 2 55 3.6E-21 T 12-10-2018 UA74_29830 d0b752d17f44dcc36e11213bcc60d6eb 140 SUPERFAMILY SSF54593 7 124 3.89E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_15760 1452bc841c8c50a3b17b208f2849e7b2 322 Pfam PF00248 Aldo/keto reductase family 25 301 5.6E-23 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_15760 1452bc841c8c50a3b17b208f2849e7b2 322 SUPERFAMILY SSF51430 24 320 2.75E-39 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_15760 1452bc841c8c50a3b17b208f2849e7b2 322 Gene3D G3DSA:3.20.20.100 19 322 1.1E-42 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_21240 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:3.20.20.80 6 692 1.9E-177 T 12-10-2018 UA74_21240 0ec86f8e3d7a9b2ce3f347352b254872 787 SMART SM00642 4 668 2.4E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_21240 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:3.30.1590.10 90 221 1.9E-177 T 12-10-2018 UA74_21240 0ec86f8e3d7a9b2ce3f347352b254872 787 Pfam PF00128 Alpha amylase, catalytic domain 25 98 1.5E-13 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UA74_21240 0ec86f8e3d7a9b2ce3f347352b254872 787 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 4 785 9.0E-253 T 12-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 UA74_21240 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:1.10.150.200 333 472 1.9E-177 T 12-10-2018 UA74_21240 0ec86f8e3d7a9b2ce3f347352b254872 787 Gene3D G3DSA:1.10.10.470 516 606 1.9E-177 T 12-10-2018 UA74_21240 0ec86f8e3d7a9b2ce3f347352b254872 787 SUPERFAMILY SSF51445 3 699 2.19E-120 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_04555 f07d04f02f18cebda9fc2759bf5a09b5 339 Gene3D G3DSA:1.10.10.10 13 100 1.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04555 f07d04f02f18cebda9fc2759bf5a09b5 339 SUPERFAMILY SSF53850 98 300 9.62E-42 T 12-10-2018 UA74_04555 f07d04f02f18cebda9fc2759bf5a09b5 339 SUPERFAMILY SSF46785 15 120 1.85E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04555 f07d04f02f18cebda9fc2759bf5a09b5 339 Pfam PF03466 LysR substrate binding domain 97 298 4.7E-48 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_04555 f07d04f02f18cebda9fc2759bf5a09b5 339 Gene3D G3DSA:3.40.190.290 101 303 7.4E-53 T 12-10-2018 UA74_04555 f07d04f02f18cebda9fc2759bf5a09b5 339 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 72 2.3E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_08790 0041cdc7b617b416f1eab866c6e53539 181 Pfam PF01202 Shikimate kinase 17 130 2.4E-10 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UA74_08790 0041cdc7b617b416f1eab866c6e53539 181 Gene3D G3DSA:3.40.50.300 8 176 5.0E-63 T 12-10-2018 UA74_08790 0041cdc7b617b416f1eab866c6e53539 181 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 11 168 2.0E-57 T 12-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 UA74_08790 0041cdc7b617b416f1eab866c6e53539 181 SUPERFAMILY SSF52540 8 171 2.38E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01005 54a53e3ca665cc683e2abab4791aefd7 344 Pfam PF13407 Periplasmic binding protein domain 65 317 8.0E-67 T 12-10-2018 IPR025997 Periplasmic binding protein UA74_01005 54a53e3ca665cc683e2abab4791aefd7 344 Gene3D G3DSA:3.40.50.2300 164 337 3.3E-82 T 12-10-2018 UA74_01005 54a53e3ca665cc683e2abab4791aefd7 344 SUPERFAMILY SSF53822 65 339 2.17E-68 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_01005 54a53e3ca665cc683e2abab4791aefd7 344 Gene3D G3DSA:3.40.50.2300 72 328 3.3E-82 T 12-10-2018 UA74_04640 8f29b31ee09985efb5860ef6fc60262d 455 Pfam PF00149 Calcineurin-like phosphoesterase 1 137 1.3E-4 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UA74_04640 8f29b31ee09985efb5860ef6fc60262d 455 SUPERFAMILY SSF56300 1 159 1.06E-20 T 12-10-2018 UA74_04640 8f29b31ee09985efb5860ef6fc60262d 455 SUPERFAMILY SSF110849 264 319 2.22E-8 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily UA74_04640 8f29b31ee09985efb5860ef6fc60262d 455 Gene3D G3DSA:3.60.21.10 41 168 2.2E-9 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_18050 4daf3f0b8c712388ed4f2d6014506157 170 SUPERFAMILY SSF46785 11 124 2.73E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18050 4daf3f0b8c712388ed4f2d6014506157 170 Gene3D G3DSA:1.10.10.10 3 149 4.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18050 4daf3f0b8c712388ed4f2d6014506157 170 Pfam PF12802 MarR family 43 95 8.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_10520 b483bf031f6fce336cb9108d9ce8f02e 188 PRINTS PR01438 Universal stress protein signature 12 30 3.2E-15 T 12-10-2018 IPR006015 Universal stress protein A UA74_10520 b483bf031f6fce336cb9108d9ce8f02e 188 PRINTS PR01438 Universal stress protein signature 130 142 3.2E-15 T 12-10-2018 IPR006015 Universal stress protein A UA74_10520 b483bf031f6fce336cb9108d9ce8f02e 188 PRINTS PR01438 Universal stress protein signature 148 170 3.2E-15 T 12-10-2018 IPR006015 Universal stress protein A UA74_10520 b483bf031f6fce336cb9108d9ce8f02e 188 Gene3D G3DSA:3.40.50.620 8 169 3.7E-35 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_10520 b483bf031f6fce336cb9108d9ce8f02e 188 Pfam PF00582 Universal stress protein family 12 170 2.2E-22 T 12-10-2018 IPR006016 UspA UA74_10520 b483bf031f6fce336cb9108d9ce8f02e 188 SUPERFAMILY SSF52402 13 172 6.11E-27 T 12-10-2018 UA74_02830 f1b9e0af48cc128e1004952d9b498c8d 137 Hamap MF_00422 Protein translocase subunit SecE [secE]. 79 134 12.757 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_02830 f1b9e0af48cc128e1004952d9b498c8d 137 Gene3D G3DSA:1.20.5.1030 78 135 2.8E-17 T 12-10-2018 IPR038379 SecE superfamily UA74_02830 f1b9e0af48cc128e1004952d9b498c8d 137 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 83 135 5.8E-19 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_02830 f1b9e0af48cc128e1004952d9b498c8d 137 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 84 112 - T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UA74_02830 f1b9e0af48cc128e1004952d9b498c8d 137 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 83 137 1.5E-20 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 UA74_19270 8ee8485ed358a03a0afe39d834dce51c 303 Gene3D G3DSA:2.120.10.30 40 204 8.5E-16 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_19270 8ee8485ed358a03a0afe39d834dce51c 303 Gene3D G3DSA:2.120.10.30 205 302 1.1E-16 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_19270 8ee8485ed358a03a0afe39d834dce51c 303 SUPERFAMILY SSF69304 41 297 8.37E-21 T 12-10-2018 UA74_19270 8ee8485ed358a03a0afe39d834dce51c 303 Pfam PF07676 WD40-like Beta Propeller Repeat 258 273 0.0088 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_19270 8ee8485ed358a03a0afe39d834dce51c 303 Pfam PF07676 WD40-like Beta Propeller Repeat 114 135 2.8E-4 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_02240 264205acbdefd99d4fd569be232c5205 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 5.4E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_02240 264205acbdefd99d4fd569be232c5205 226 SMART SM00448 2 112 1.8E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_02240 264205acbdefd99d4fd569be232c5205 226 SUPERFAMILY SSF52172 1 125 1.38E-40 T 12-10-2018 IPR011006 CheY-like superfamily UA74_02240 264205acbdefd99d4fd569be232c5205 226 Gene3D G3DSA:1.10.10.10 121 226 2.0E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02240 264205acbdefd99d4fd569be232c5205 226 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_02240 264205acbdefd99d4fd569be232c5205 226 SMART SM00862 148 224 1.1E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_02240 264205acbdefd99d4fd569be232c5205 226 SUPERFAMILY SSF46894 124 225 9.92E-33 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_02240 264205acbdefd99d4fd569be232c5205 226 Gene3D G3DSA:3.40.50.2300 1 120 1.3E-35 T 12-10-2018 UA74_28305 120957dd64eb63106c1a10664f760d0e 190 Pfam PF00588 SpoU rRNA Methylase family 36 175 6.5E-28 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_28305 120957dd64eb63106c1a10664f760d0e 190 Gene3D G3DSA:3.40.1280.10 24 181 1.0E-43 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_28305 120957dd64eb63106c1a10664f760d0e 190 SUPERFAMILY SSF75217 12 178 3.53E-36 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_09000 310aa0742e7e63673302061afdcc4e11 303 SUPERFAMILY SSF161098 30 281 4.02E-52 T 12-10-2018 IPR035906 MetI-like superfamily UA74_09000 310aa0742e7e63673302061afdcc4e11 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 285 1.5E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_09000 310aa0742e7e63673302061afdcc4e11 303 Gene3D G3DSA:1.10.3720.10 36 292 4.1E-49 T 12-10-2018 IPR035906 MetI-like superfamily UA74_24150 80aa2805751e3701e98d9fcb394d09b1 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 6.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_24150 80aa2805751e3701e98d9fcb394d09b1 229 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 6.0E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_24150 80aa2805751e3701e98d9fcb394d09b1 229 SUPERFAMILY SSF48498 86 175 1.65E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_24150 80aa2805751e3701e98d9fcb394d09b1 229 SUPERFAMILY SSF46689 9 79 7.48E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_24150 80aa2805751e3701e98d9fcb394d09b1 229 Gene3D G3DSA:1.10.357.10 7 208 2.7E-29 T 12-10-2018 UA74_24150 80aa2805751e3701e98d9fcb394d09b1 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 8.7E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_20700 7e0ee536a90afafbae099d8682c5b267 285 Pfam PF01261 Xylose isomerase-like TIM barrel 26 216 2.2E-27 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_20700 7e0ee536a90afafbae099d8682c5b267 285 SUPERFAMILY SSF51658 1 263 2.09E-57 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_20700 7e0ee536a90afafbae099d8682c5b267 285 Gene3D G3DSA:3.20.20.150 1 285 1.7E-69 T 12-10-2018 UA74_02200 735c3ac7d7cf23f7783a3f7db63194bd 253 Gene3D G3DSA:3.10.180.10 135 253 1.1E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_02200 735c3ac7d7cf23f7783a3f7db63194bd 253 SUPERFAMILY SSF54593 15 186 9.42E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_02200 735c3ac7d7cf23f7783a3f7db63194bd 253 Gene3D G3DSA:3.10.180.10 1 134 6.1E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_02200 735c3ac7d7cf23f7783a3f7db63194bd 253 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 146 247 6.8E-5 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_02200 735c3ac7d7cf23f7783a3f7db63194bd 253 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 17 121 2.1E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_17670 59d8d94c7d6fc23e7b4ec0edbe0c063e 448 Pfam PF07690 Major Facilitator Superfamily 21 369 2.5E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_17670 59d8d94c7d6fc23e7b4ec0edbe0c063e 448 SUPERFAMILY SSF103473 12 404 1.57E-39 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_17670 59d8d94c7d6fc23e7b4ec0edbe0c063e 448 Gene3D G3DSA:1.20.1250.20 9 406 2.9E-34 T 12-10-2018 UA74_27395 43458408e142c5f3aa4550eea3115e24 329 Pfam PF01791 DeoC/LacD family aldolase 67 305 7.9E-23 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 UA74_27395 43458408e142c5f3aa4550eea3115e24 329 Gene3D G3DSA:3.20.20.70 61 313 3.5E-83 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_27395 43458408e142c5f3aa4550eea3115e24 329 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 72 291 1.2E-49 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 UA74_27395 43458408e142c5f3aa4550eea3115e24 329 SUPERFAMILY SSF51569 67 309 1.02E-69 T 12-10-2018 UA74_27395 43458408e142c5f3aa4550eea3115e24 329 SMART SM01133 70 310 2.8E-62 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 UA74_27395 43458408e142c5f3aa4550eea3115e24 329 PIRSF PIRSF001357 65 319 1.4E-74 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 UA74_29925 baedc40b413cea754becca9b4744dd37 462 Gene3D G3DSA:3.30.559.10 220 458 3.0E-82 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UA74_29925 baedc40b413cea754becca9b4744dd37 462 Gene3D G3DSA:4.10.320.10 168 219 4.2E-12 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UA74_29925 baedc40b413cea754becca9b4744dd37 462 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 232 460 8.4E-81 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 UA74_29925 baedc40b413cea754becca9b4744dd37 462 Pfam PF02817 e3 binding domain 178 212 6.6E-11 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 UA74_29925 baedc40b413cea754becca9b4744dd37 462 Pfam PF00364 Biotin-requiring enzyme 6 78 1.3E-19 T 12-10-2018 IPR000089 Biotin/lipoyl attachment UA74_29925 baedc40b413cea754becca9b4744dd37 462 SUPERFAMILY SSF51230 4 93 6.02E-24 T 12-10-2018 IPR011053 Single hybrid motif UA74_29925 baedc40b413cea754becca9b4744dd37 462 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UA74_29925 baedc40b413cea754becca9b4744dd37 462 SUPERFAMILY SSF52777 227 458 3.25E-79 T 12-10-2018 UA74_29925 baedc40b413cea754becca9b4744dd37 462 SUPERFAMILY SSF47005 174 216 1.44E-9 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UA74_29925 baedc40b413cea754becca9b4744dd37 462 Gene3D G3DSA:2.40.50.100 1 98 3.8E-21 T 12-10-2018 UA74_03595 b8313df33ab49115815a86119cae2f0a 413 Gene3D G3DSA:3.30.9.30 50 288 2.7E-73 T 12-10-2018 UA74_03595 b8313df33ab49115815a86119cae2f0a 413 SUPERFAMILY SSF51905 14 385 4.68E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_03595 b8313df33ab49115815a86119cae2f0a 413 Gene3D G3DSA:3.50.50.60 15 357 2.7E-73 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_03595 b8313df33ab49115815a86119cae2f0a 413 Pfam PF01494 FAD binding domain 12 355 1.7E-27 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_03595 b8313df33ab49115815a86119cae2f0a 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 13 35 1.4E-19 T 12-10-2018 UA74_03595 b8313df33ab49115815a86119cae2f0a 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 1.4E-19 T 12-10-2018 UA74_03595 b8313df33ab49115815a86119cae2f0a 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 1.4E-19 T 12-10-2018 UA74_03595 b8313df33ab49115815a86119cae2f0a 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 1.4E-19 T 12-10-2018 UA74_03405 0de8d34b862a077ca86d7a54a6a33ad1 399 SMART SM00387 293 390 1.0E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_03405 0de8d34b862a077ca86d7a54a6a33ad1 399 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 295 389 9.5E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_03405 0de8d34b862a077ca86d7a54a6a33ad1 399 PIRSF PIRSF037434 1 395 3.3E-62 T 12-10-2018 IPR017205 Signal transduction histidine kinase, ChrS UA74_03405 0de8d34b862a077ca86d7a54a6a33ad1 399 Gene3D G3DSA:3.30.565.10 259 389 1.5E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_03405 0de8d34b862a077ca86d7a54a6a33ad1 399 SUPERFAMILY SSF55874 258 388 7.2E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_03405 0de8d34b862a077ca86d7a54a6a33ad1 399 Pfam PF07730 Histidine kinase 189 254 2.6E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_03405 0de8d34b862a077ca86d7a54a6a33ad1 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 343 4.2E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_03405 0de8d34b862a077ca86d7a54a6a33ad1 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 387 4.2E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_03405 0de8d34b862a077ca86d7a54a6a33ad1 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 368 4.2E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UA74_03560 a49019f584d08b5f958a1dc5a6e44c0a 280 SUPERFAMILY SSF53850 43 280 3.43E-71 T 12-10-2018 UA74_03560 a49019f584d08b5f958a1dc5a6e44c0a 280 Gene3D G3DSA:3.40.190.10 125 229 1.8E-88 T 12-10-2018 UA74_03560 a49019f584d08b5f958a1dc5a6e44c0a 280 Gene3D G3DSA:3.40.190.10 43 276 1.8E-88 T 12-10-2018 UA74_03560 a49019f584d08b5f958a1dc5a6e44c0a 280 PIRSF PIRSF002854 1 280 1.5E-92 T 12-10-2018 IPR004872 Lipoprotein NlpA family UA74_03560 a49019f584d08b5f958a1dc5a6e44c0a 280 Pfam PF03180 NLPA lipoprotein 43 279 6.3E-78 T 12-10-2018 IPR004872 Lipoprotein NlpA family UA74_09080 bec50925cdf3908735d9b3db48f91ec5 412 Pfam PF04892 VanZ like family 48 188 1.2E-17 T 12-10-2018 IPR006976 VanZ-like UA74_07850 193c13a82553b90558deb19f1e99761b 678 Pfam PF05425 Copper resistance protein D 250 346 4.7E-17 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 UA74_07850 193c13a82553b90558deb19f1e99761b 678 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 400 643 3.2E-86 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related UA74_13520 f02c5a40feaea32729dc409c801413db 548 SUPERFAMILY SSF56801 4 511 4.32E-157 T 12-10-2018 UA74_13520 f02c5a40feaea32729dc409c801413db 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_13520 f02c5a40feaea32729dc409c801413db 548 Gene3D G3DSA:3.30.300.310 410 515 3.7E-31 T 12-10-2018 UA74_13520 f02c5a40feaea32729dc409c801413db 548 Gene3D G3DSA:3.40.50.12780 1 407 1.1E-122 T 12-10-2018 UA74_13520 f02c5a40feaea32729dc409c801413db 548 Pfam PF00501 AMP-binding enzyme 10 414 8.7E-112 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_13520 f02c5a40feaea32729dc409c801413db 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 499 7.5E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_14225 5b38be69071c14b5b34e510b046621af 264 SMART SM00420 12 64 7.1E-11 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_14225 5b38be69071c14b5b34e510b046621af 264 Gene3D G3DSA:1.10.10.10 2 66 1.9E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14225 5b38be69071c14b5b34e510b046621af 264 SUPERFAMILY SSF100950 82 239 1.67E-24 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_14225 5b38be69071c14b5b34e510b046621af 264 ProSitePatterns PS00894 DeoR-type HTH domain signature. 12 46 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_14225 5b38be69071c14b5b34e510b046621af 264 SUPERFAMILY SSF46785 10 81 7.89E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14225 5b38be69071c14b5b34e510b046621af 264 Pfam PF08220 DeoR-like helix-turn-helix domain 12 67 6.2E-11 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UA74_14225 5b38be69071c14b5b34e510b046621af 264 Pfam PF00455 DeoR C terminal sensor domain 83 238 1.6E-43 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain UA74_14225 5b38be69071c14b5b34e510b046621af 264 SMART SM01134 79 240 1.2E-58 T 12-10-2018 UA74_02120 ce5e9d07ac6ef99b651a42b166f373c4 378 Gene3D G3DSA:3.40.50.300 155 239 1.8E-7 T 12-10-2018 UA74_02120 ce5e9d07ac6ef99b651a42b166f373c4 378 SUPERFAMILY SSF53795 158 246 2.53E-10 T 12-10-2018 UA74_01865 c2a31b6bf4ab92aca03807cf4a36592a 181 Pfam PF02698 DUF218 domain 21 136 2.3E-16 T 12-10-2018 IPR003848 Domain of unknown function DUF218 UA74_22740 d60f3ef62d5ced6519b79e2521cbac78 436 Gene3D G3DSA:2.40.37.20 44 436 1.1E-124 T 12-10-2018 UA74_22740 d60f3ef62d5ced6519b79e2521cbac78 436 Pfam PF14031 Putative serine dehydratase domain 325 418 2.7E-13 T 12-10-2018 IPR026956 D-serine dehydratase-like domain UA74_22740 d60f3ef62d5ced6519b79e2521cbac78 436 Gene3D G3DSA:3.20.20.10 61 301 1.1E-124 T 12-10-2018 IPR029066 PLP-binding barrel UA74_22740 d60f3ef62d5ced6519b79e2521cbac78 436 Pfam PF01168 Alanine racemase, N-terminal domain 60 267 5.6E-14 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UA74_22740 d60f3ef62d5ced6519b79e2521cbac78 436 SUPERFAMILY SSF51419 61 303 1.05E-22 T 12-10-2018 IPR029066 PLP-binding barrel UA74_22740 d60f3ef62d5ced6519b79e2521cbac78 436 SMART SM01119 325 423 3.2E-24 T 12-10-2018 IPR026956 D-serine dehydratase-like domain UA74_25575 4e5d2e80c6ec2429e71819c558558cc6 553 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 552 4.8E-192 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 UA74_25575 4e5d2e80c6ec2429e71819c558558cc6 553 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 553 31.056 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 UA74_25575 4e5d2e80c6ec2429e71819c558558cc6 553 PIRSF PIRSF001294 4 553 5.3E-201 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 UA74_25575 4e5d2e80c6ec2429e71819c558558cc6 553 Pfam PF03814 Potassium-transporting ATPase A subunit 14 552 5.1E-213 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 UA74_12380 39de96c2dcb598504436a4e93ec0ab25 135 Gene3D G3DSA:1.10.490.110 2 129 1.2E-16 T 12-10-2018 UA74_12380 39de96c2dcb598504436a4e93ec0ab25 135 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 3 125 4.7E-35 T 12-10-2018 IPR018727 Protein of unknown function DUF2267 UA74_05130 1edae2234e9e7a62d42c449ddc9141cf 588 Pfam PF00664 ABC transporter transmembrane region 38 299 4.7E-31 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UA74_05130 1edae2234e9e7a62d42c449ddc9141cf 588 Pfam PF00005 ABC transporter 360 517 1.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_05130 1edae2234e9e7a62d42c449ddc9141cf 588 SUPERFAMILY SSF90123 18 325 1.44E-53 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_05130 1edae2234e9e7a62d42c449ddc9141cf 588 SMART SM00382 369 563 5.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_05130 1edae2234e9e7a62d42c449ddc9141cf 588 Gene3D G3DSA:3.40.50.300 335 587 2.5E-72 T 12-10-2018 UA74_05130 1edae2234e9e7a62d42c449ddc9141cf 588 Gene3D G3DSA:1.20.1560.10 5 330 7.4E-51 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UA74_05130 1edae2234e9e7a62d42c449ddc9141cf 588 SUPERFAMILY SSF52540 340 587 8.33E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_09570 0cf7be89f928ba44561eadf673ffd7a9 277 Pfam PF13614 AAA domain 3 183 4.3E-29 T 12-10-2018 IPR025669 AAA domain UA74_09570 0cf7be89f928ba44561eadf673ffd7a9 277 Gene3D G3DSA:3.40.50.300 1 267 6.8E-55 T 12-10-2018 UA74_09570 0cf7be89f928ba44561eadf673ffd7a9 277 SUPERFAMILY SSF52540 2 253 7.04E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22025 b6913f865c8e2537b63d70ce7a5f2b62 241 SUPERFAMILY SSF51735 2 238 1.15E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22025 b6913f865c8e2537b63d70ce7a5f2b62 241 Gene3D G3DSA:3.40.50.720 4 239 4.4E-56 T 12-10-2018 UA74_22025 b6913f865c8e2537b63d70ce7a5f2b62 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 236 1.1E-39 T 12-10-2018 UA74_22025 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 5.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22025 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 5.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22025 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22025 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 5.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22025 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 5.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22025 b6913f865c8e2537b63d70ce7a5f2b62 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 5.2E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_13365 0adc1a39a8051ea4ef5e037277735489 125 Pfam PF04075 F420H(2)-dependent quinone reductase 2 124 2.5E-35 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_13365 0adc1a39a8051ea4ef5e037277735489 125 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 11 123 2.4E-32 T 12-10-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 UA74_13365 0adc1a39a8051ea4ef5e037277735489 125 Gene3D G3DSA:2.30.110.10 1 125 2.4E-48 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_09595 cd4b09cac13a1d2167052229847dbc22 364 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 64 193 2.6E-62 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 UA74_09595 cd4b09cac13a1d2167052229847dbc22 364 SUPERFAMILY SSF52540 42 308 1.65E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_09595 cd4b09cac13a1d2167052229847dbc22 364 Gene3D G3DSA:3.40.50.300 29 226 5.8E-43 T 12-10-2018 UA74_09595 cd4b09cac13a1d2167052229847dbc22 364 Gene3D G3DSA:1.10.8.300 227 333 3.9E-30 T 12-10-2018 UA74_09595 cd4b09cac13a1d2167052229847dbc22 364 PIRSF PIRSF002849 4 338 3.0E-129 T 12-10-2018 UA74_10770 fdbf9962a61deee07898600600e97366 451 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 22 304 3.2E-68 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 UA74_00025 3733a49c4ce7587ae6effb02718100de 202 Pfam PF05258 Protein of unknown function (DUF721) 91 177 8.4E-23 T 12-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 UA74_00025 3733a49c4ce7587ae6effb02718100de 202 Hamap MF_00630 UPF0232 protein . 9 189 29.567 T 12-10-2018 IPR023007 Uncharacterised protein family UPF0232, actinobacteria UA74_15145 c13a47c2d65ccfa258e8e998183f935f 318 Pfam PF00589 Phage integrase family 142 298 1.0E-15 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_15145 c13a47c2d65ccfa258e8e998183f935f 318 SUPERFAMILY SSF56349 21 299 2.03E-28 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_15145 c13a47c2d65ccfa258e8e998183f935f 318 Gene3D G3DSA:1.10.443.10 121 314 6.6E-22 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_28710 2edfc2bb4e9abd573306e87eb0551cbe 113 SUPERFAMILY SSF46785 6 105 9.89E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_28710 2edfc2bb4e9abd573306e87eb0551cbe 113 Gene3D G3DSA:1.10.10.10 4 111 6.3E-42 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28710 2edfc2bb4e9abd573306e87eb0551cbe 113 Pfam PF01638 HxlR-like helix-turn-helix 16 104 1.5E-33 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 Pfam PF00551 Formyl transferase 86 265 1.6E-37 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 Gene3D G3DSA:3.40.50.170 84 285 7.3E-67 T 12-10-2018 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 SUPERFAMILY SSF55021 1 76 2.54E-12 T 12-10-2018 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 SUPERFAMILY SSF53328 86 285 7.98E-56 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 285 44.799 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 Gene3D G3DSA:3.30.70.260 1 83 4.1E-21 T 12-10-2018 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 3 285 6.8E-98 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 2 28 1.2E-57 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 108 135 1.2E-57 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 237 259 1.2E-57 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 34 46 1.2E-57 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 86 108 1.2E-57 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 259 284 1.2E-57 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UA74_02150 eed5a4430c974a4699c1b0106f5311cb 285 PIRSF PIRSF036480 1 285 8.0E-105 T 12-10-2018 UA74_15105 733b91e34863d8a3d7c2c8788a2de684 292 Pfam PF00376 MerR family regulatory protein 12 49 1.3E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15105 733b91e34863d8a3d7c2c8788a2de684 292 SMART SM00422 11 80 2.3E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15105 733b91e34863d8a3d7c2c8788a2de684 292 Gene3D G3DSA:1.10.1660.10 8 125 1.0E-22 T 12-10-2018 UA74_15105 733b91e34863d8a3d7c2c8788a2de684 292 SUPERFAMILY SSF46955 12 121 2.23E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_15105 733b91e34863d8a3d7c2c8788a2de684 292 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 2.5E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15105 733b91e34863d8a3d7c2c8788a2de684 292 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 2.5E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_15105 733b91e34863d8a3d7c2c8788a2de684 292 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 2.5E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_23285 0f87ee8393ce061f2d691d7010a7bedf 424 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 277 402 7.7E-26 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UA74_23285 0f87ee8393ce061f2d691d7010a7bedf 424 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 260 1.0E-88 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UA74_23285 0f87ee8393ce061f2d691d7010a7bedf 424 PIRSF PIRSF006446 270 422 1.7E-27 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UA74_23285 0f87ee8393ce061f2d691d7010a7bedf 424 PIRSF PIRSF006446 1 272 2.3E-79 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UA74_22775 fb5f84275272f1784cddfc5c48238479 338 Pfam PF00248 Aldo/keto reductase family 33 330 1.9E-72 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_22775 fb5f84275272f1784cddfc5c48238479 338 Gene3D G3DSA:3.20.20.100 19 334 4.3E-110 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_22775 fb5f84275272f1784cddfc5c48238479 338 SUPERFAMILY SSF51430 21 330 1.13E-96 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_29690 c5eb022be314763882660b9fd2aeecf7 1108 Pfam PF12229 Putative peptidoglycan binding domain 750 848 3.2E-10 T 12-10-2018 IPR022029 Putative peptidoglycan binding domain UA74_29690 c5eb022be314763882660b9fd2aeecf7 1108 Pfam PF04294 VanW like protein 896 1026 2.6E-38 T 12-10-2018 IPR007391 Vancomycin resistance VanW UA74_07490 76f268a606b2abaaf5a77063c5c6a78b 177 Gene3D G3DSA:1.10.10.60 41 150 2.1E-27 T 12-10-2018 UA74_07490 76f268a606b2abaaf5a77063c5c6a78b 177 SUPERFAMILY SSF46689 45 95 2.78E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_07490 76f268a606b2abaaf5a77063c5c6a78b 177 Pfam PF12833 Helix-turn-helix domain 67 144 6.7E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_07490 76f268a606b2abaaf5a77063c5c6a78b 177 SUPERFAMILY SSF46689 97 145 3.76E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_07490 76f268a606b2abaaf5a77063c5c6a78b 177 SMART SM00342 61 144 1.3E-31 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UA74_05500 d6deb194d5bf8385306f3c4659f921f8 257 SUPERFAMILY SSF51735 8 255 2.69E-64 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_05500 d6deb194d5bf8385306f3c4659f921f8 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 8.4E-49 T 12-10-2018 UA74_05500 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05500 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05500 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05500 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05500 d6deb194d5bf8385306f3c4659f921f8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 4.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05500 d6deb194d5bf8385306f3c4659f921f8 257 Gene3D G3DSA:3.40.50.720 3 257 4.0E-66 T 12-10-2018 UA74_05500 d6deb194d5bf8385306f3c4659f921f8 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_20200 c77b9a89b6ae722d1d33fbaa797ab082 65 Pfam PF04149 Domain of unknown function (DUF397) 10 60 3.9E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_06520 9d34f5f53835bd1a57028bb5db76e6b4 328 Gene3D G3DSA:3.90.1200.10 128 298 3.2E-12 T 12-10-2018 UA74_06520 9d34f5f53835bd1a57028bb5db76e6b4 328 PIRSF PIRSF000707 7 328 5.8E-92 T 12-10-2018 IPR016259 Hygromycin-B kinase UA74_06520 9d34f5f53835bd1a57028bb5db76e6b4 328 SUPERFAMILY SSF56112 64 295 4.34E-25 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_06520 9d34f5f53835bd1a57028bb5db76e6b4 328 Pfam PF01636 Phosphotransferase enzyme family 64 278 1.1E-22 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_02280 ca23d031d7215ad4b091a9b3a51c60aa 417 SUPERFAMILY SSF69593 184 408 6.8E-32 T 12-10-2018 UA74_02280 ca23d031d7215ad4b091a9b3a51c60aa 417 PIRSF PIRSF016753 115 416 1.4E-97 T 12-10-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted UA74_02280 ca23d031d7215ad4b091a9b3a51c60aa 417 Pfam PF01553 Acyltransferase 190 319 2.6E-15 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_02280 ca23d031d7215ad4b091a9b3a51c60aa 417 SMART SM00563 203 322 9.8E-15 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_29035 b8ab21378bc87ac7470fcc4d4d3f6a42 290 SUPERFAMILY SSF53474 5 274 7.84E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_29035 b8ab21378bc87ac7470fcc4d4d3f6a42 290 Gene3D G3DSA:3.40.50.1820 1 278 1.1E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_29035 b8ab21378bc87ac7470fcc4d4d3f6a42 290 Pfam PF00561 alpha/beta hydrolase fold 23 272 1.7E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_27575 472aaeeec4b115e9d64dcfc08a06f77c 430 Gene3D G3DSA:3.30.540.10 168 303 1.8E-16 T 12-10-2018 UA74_27575 472aaeeec4b115e9d64dcfc08a06f77c 430 SUPERFAMILY SSF56655 172 422 1.83E-37 T 12-10-2018 UA74_27575 472aaeeec4b115e9d64dcfc08a06f77c 430 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 250 262 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site UA74_27575 472aaeeec4b115e9d64dcfc08a06f77c 430 Pfam PF00459 Inositol monophosphatase family 182 423 9.4E-15 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_27575 472aaeeec4b115e9d64dcfc08a06f77c 430 PRINTS PR00377 Inositol monophosphatase superfamily signature 368 392 2.9E-7 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_27575 472aaeeec4b115e9d64dcfc08a06f77c 430 PRINTS PR00377 Inositol monophosphatase superfamily signature 249 265 2.9E-7 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_27575 472aaeeec4b115e9d64dcfc08a06f77c 430 PRINTS PR00377 Inositol monophosphatase superfamily signature 334 355 2.9E-7 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UA74_27575 472aaeeec4b115e9d64dcfc08a06f77c 430 Gene3D G3DSA:3.40.190.80 320 423 1.7E-17 T 12-10-2018 UA74_10740 63be363233e34ce20dafee9d37ffca1d 224 Pfam PF08808 RES domain 32 202 1.7E-19 T 12-10-2018 IPR014914 RES domain UA74_10740 63be363233e34ce20dafee9d37ffca1d 224 SMART SM00953 66 196 1.4E-5 T 12-10-2018 IPR014914 RES domain UA74_25310 eb5ddf5bd96d55ac8bd71f80ca214b41 248 SUPERFAMILY SSF55486 99 235 5.38E-19 T 12-10-2018 UA74_25310 eb5ddf5bd96d55ac8bd71f80ca214b41 248 Gene3D G3DSA:3.40.390.10 110 239 1.3E-6 T 12-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 UA74_25310 eb5ddf5bd96d55ac8bd71f80ca214b41 248 Pfam PF11350 Protein of unknown function (DUF3152) 78 238 3.3E-47 T 12-10-2018 IPR022603 Domain of unknown function DUF3152 UA74_11035 9f3dcee12558ba71da346f2c2ab0a17b 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 17 74 5.4E-9 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_11035 9f3dcee12558ba71da346f2c2ab0a17b 100 SUPERFAMILY SSF54909 10 98 1.83E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_11035 9f3dcee12558ba71da346f2c2ab0a17b 100 Gene3D G3DSA:3.30.70.100 5 97 3.6E-15 T 12-10-2018 UA74_18720 97351d96a67157e6a3f7242d26c2baaa 413 SUPERFAMILY SSF53850 21 410 4.3E-65 T 12-10-2018 UA74_18720 97351d96a67157e6a3f7242d26c2baaa 413 Gene3D G3DSA:3.40.190.10 20 409 3.5E-70 T 12-10-2018 UA74_18720 97351d96a67157e6a3f7242d26c2baaa 413 Pfam PF13416 Bacterial extracellular solute-binding protein 57 351 1.5E-31 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_23210 81c19d594a00687589e2e5cff253c17f 450 Pfam PF13560 Helix-turn-helix domain 34 86 1.1E-6 T 12-10-2018 UA74_23210 81c19d594a00687589e2e5cff253c17f 450 Gene3D G3DSA:1.10.260.40 14 85 9.2E-7 T 12-10-2018 UA74_23210 81c19d594a00687589e2e5cff253c17f 450 SMART SM00530 33 88 4.7E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_23210 81c19d594a00687589e2e5cff253c17f 450 SUPERFAMILY SSF48452 185 314 4.61E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23210 81c19d594a00687589e2e5cff253c17f 450 SUPERFAMILY SSF47413 35 85 2.55E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_23210 81c19d594a00687589e2e5cff253c17f 450 Gene3D G3DSA:1.25.40.10 191 348 9.9E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_23420 6f5b3f3997846ab0845697aa2e9b4bf4 452 PIRSF PIRSF017901 3 451 2.3E-95 T 12-10-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_23420 6f5b3f3997846ab0845697aa2e9b4bf4 452 Gene3D G3DSA:3.30.590.20 1 449 3.0E-116 T 12-10-2018 UA74_23420 6f5b3f3997846ab0845697aa2e9b4bf4 452 SUPERFAMILY SSF55931 23 436 6.77E-44 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UA74_23420 6f5b3f3997846ab0845697aa2e9b4bf4 452 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 76 354 1.6E-42 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 UA74_10530 6226e765b25807a923b404ffbd5f0470 223 SUPERFAMILY SSF48498 101 200 2.22E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_10530 6226e765b25807a923b404ffbd5f0470 223 SUPERFAMILY SSF46689 20 78 2.05E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_10530 6226e765b25807a923b404ffbd5f0470 223 Gene3D G3DSA:1.10.10.60 21 66 9.6E-19 T 12-10-2018 UA74_10530 6226e765b25807a923b404ffbd5f0470 223 Gene3D G3DSA:1.10.357.10 67 217 2.7E-18 T 12-10-2018 UA74_10530 6226e765b25807a923b404ffbd5f0470 223 ProSitePatterns PS01081 TetR-type HTH domain signature. 40 70 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_10530 6226e765b25807a923b404ffbd5f0470 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 42 73 1.1E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03760 ff2c7c8533ccdc0abdb4fbf3ef47084e 169 Pfam PF13160 Protein of unknown function (DUF3995) 27 155 1.2E-17 T 12-10-2018 IPR025058 Protein of unknown function DUF3995 UA74_25945 e99016deaf0074a9e7f289fd00906014 225 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 38 131 8.0E-10 T 12-10-2018 IPR020535 Low molecular weight antigen Cfp6 UA74_25945 e99016deaf0074a9e7f289fd00906014 225 Pfam PF10756 Bacterial PH domain 61 131 3.8E-12 T 12-10-2018 IPR019692 Protein of unknown function DUF2581 UA74_13840 02ab8bf62b60a7dc855a90762e0050af 288 Gene3D G3DSA:3.20.20.150 29 288 1.4E-68 T 12-10-2018 UA74_13840 02ab8bf62b60a7dc855a90762e0050af 288 Pfam PF01261 Xylose isomerase-like TIM barrel 72 245 1.9E-14 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_13840 02ab8bf62b60a7dc855a90762e0050af 288 SUPERFAMILY SSF51658 46 286 2.33E-37 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_12075 a5051e7add88d7b70e2cdef5f66eafee 106 Pfam PF04149 Domain of unknown function (DUF397) 31 48 3.5E-5 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_12075 a5051e7add88d7b70e2cdef5f66eafee 106 Pfam PF04149 Domain of unknown function (DUF397) 10 28 1.1E-5 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_12075 a5051e7add88d7b70e2cdef5f66eafee 106 Pfam PF04149 Domain of unknown function (DUF397) 52 102 4.7E-21 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_12435 225fa36be73ff906cd8fdd433e261ed0 190 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 2.1E-5 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_12435 225fa36be73ff906cd8fdd433e261ed0 190 Gene3D G3DSA:1.10.10.10 1 88 8.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12435 225fa36be73ff906cd8fdd433e261ed0 190 Pfam PF10400 Virulence activator alpha C-term 92 179 1.8E-15 T 12-10-2018 IPR018309 Transcription regulator PadR, C-terminal UA74_12435 225fa36be73ff906cd8fdd433e261ed0 190 SUPERFAMILY SSF46785 3 179 1.88E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_12970 0ff42c8ccd1eefb41cc15b961ec207cb 359 Gene3D G3DSA:3.40.50.1110 38 330 1.7E-49 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_12970 0ff42c8ccd1eefb41cc15b961ec207cb 359 SUPERFAMILY SSF52266 44 328 8.49E-39 T 12-10-2018 UA74_12970 0ff42c8ccd1eefb41cc15b961ec207cb 359 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 46 319 5.0E-15 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain UA74_23000 f6b2e8d2c3c464d4a34780f38500d067 279 Gene3D G3DSA:3.60.10.10 2 255 5.1E-31 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_23000 f6b2e8d2c3c464d4a34780f38500d067 279 SUPERFAMILY SSF56219 2 253 2.88E-29 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_23000 f6b2e8d2c3c464d4a34780f38500d067 279 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 205 4.0E-7 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase UA74_04725 2c70f2f4e34efcc4a5fc57e35e020174 429 SUPERFAMILY SSF53474 96 386 3.0E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_04725 2c70f2f4e34efcc4a5fc57e35e020174 429 PRINTS PR00111 Alpha/beta hydrolase fold signature 149 164 7.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_04725 2c70f2f4e34efcc4a5fc57e35e020174 429 PRINTS PR00111 Alpha/beta hydrolase fold signature 208 221 7.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_04725 2c70f2f4e34efcc4a5fc57e35e020174 429 PRINTS PR00111 Alpha/beta hydrolase fold signature 194 207 7.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_04725 2c70f2f4e34efcc4a5fc57e35e020174 429 Gene3D G3DSA:3.40.50.1820 95 390 3.2E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_04725 2c70f2f4e34efcc4a5fc57e35e020174 429 Pfam PF00561 alpha/beta hydrolase fold 127 376 1.0E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_27165 5df395100fe4842f63c57d85a92182be 491 PIRSF PIRSF026631 1 479 1.5E-54 T 12-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 UA74_27165 5df395100fe4842f63c57d85a92182be 491 Pfam PF03703 Bacterial PH domain 409 478 1.1E-5 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_27165 5df395100fe4842f63c57d85a92182be 491 Pfam PF03703 Bacterial PH domain 64 144 3.8E-11 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_27165 5df395100fe4842f63c57d85a92182be 491 Pfam PF03703 Bacterial PH domain 241 302 3.3E-6 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_22990 c3b2768faaafe10fddb23b6685165729 68 Gene3D G3DSA:3.30.470.20 1 67 1.2E-11 T 12-10-2018 UA74_22990 c3b2768faaafe10fddb23b6685165729 68 SUPERFAMILY SSF56059 6 65 3.36E-8 T 12-10-2018 UA74_29890 60ad4d87c81a4d97c981d02a02ab4aee 272 Gene3D G3DSA:3.40.50.300 19 271 4.3E-76 T 12-10-2018 UA74_29890 60ad4d87c81a4d97c981d02a02ab4aee 272 Pfam PF00005 ABC transporter 37 185 8.0E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_29890 60ad4d87c81a4d97c981d02a02ab4aee 272 PIRSF PIRSF039085 18 261 2.8E-111 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UA74_29890 60ad4d87c81a4d97c981d02a02ab4aee 272 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_29890 60ad4d87c81a4d97c981d02a02ab4aee 272 SMART SM00382 46 233 1.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_29890 60ad4d87c81a4d97c981d02a02ab4aee 272 SUPERFAMILY SSF52540 21 255 7.99E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04535 00b8177134540e59c68d782f56e2bc56 313 Gene3D G3DSA:3.90.226.10 54 255 1.1E-68 T 12-10-2018 UA74_04535 00b8177134540e59c68d782f56e2bc56 313 Pfam PF00378 Enoyl-CoA hydratase/isomerase 61 311 7.5E-63 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UA74_04535 00b8177134540e59c68d782f56e2bc56 313 Gene3D G3DSA:1.10.12.10 256 313 1.8E-20 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal UA74_04535 00b8177134540e59c68d782f56e2bc56 313 SUPERFAMILY SSF52096 55 312 8.19E-81 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_09475 e16df43ee6b077d2fe15f967690abd84 187 Pfam PF05534 HicB family 110 140 2.7E-6 T 12-10-2018 IPR008651 Uncharacterised protein family HicB UA74_09475 e16df43ee6b077d2fe15f967690abd84 187 SUPERFAMILY SSF47598 105 157 4.89E-10 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 UA74_24410 061cdb6e9590ae10add583d3b9cf7565 357 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 141 355 4.7E-32 T 12-10-2018 IPR015402 Protein of unknown function DUF1980 UA74_15925 a490d15e031633bcdca81dbbcc6c608b 402 SUPERFAMILY SSF116734 7 188 1.06E-22 T 12-10-2018 UA74_15925 a490d15e031633bcdca81dbbcc6c608b 402 Gene3D G3DSA:3.90.220.20 205 390 2.0E-16 T 12-10-2018 UA74_15925 a490d15e031633bcdca81dbbcc6c608b 402 SUPERFAMILY SSF116734 223 396 5.89E-18 T 12-10-2018 UA74_15925 a490d15e031633bcdca81dbbcc6c608b 402 Gene3D G3DSA:3.90.220.20 2 176 1.4E-23 T 12-10-2018 UA74_08030 57391b1bb3a461c794e78f43c284080d 265 Gene3D G3DSA:3.40.80.10 3 162 1.5E-29 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_08030 57391b1bb3a461c794e78f43c284080d 265 Pfam PF01471 Putative peptidoglycan binding domain 192 244 4.1E-9 T 12-10-2018 IPR002477 Peptidoglycan binding-like UA74_08030 57391b1bb3a461c794e78f43c284080d 265 SUPERFAMILY SSF55846 3 161 7.77E-27 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_08030 57391b1bb3a461c794e78f43c284080d 265 SMART SM00701 2 126 6.2E-4 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_08030 57391b1bb3a461c794e78f43c284080d 265 SUPERFAMILY SSF47090 187 245 9.02E-11 T 12-10-2018 IPR036365 PGBD-like superfamily UA74_08030 57391b1bb3a461c794e78f43c284080d 265 Gene3D G3DSA:1.10.101.10 180 248 6.2E-14 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UA74_17285 0b084f99f89e8f9e716ccf022335da56 402 Gene3D G3DSA:3.90.1150.10 246 368 7.2E-38 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_17285 0b084f99f89e8f9e716ccf022335da56 402 SUPERFAMILY SSF53383 15 366 1.34E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_17285 0b084f99f89e8f9e716ccf022335da56 402 Gene3D G3DSA:3.40.640.10 1 244 5.3E-89 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_17285 0b084f99f89e8f9e716ccf022335da56 402 PIRSF PIRSF000390 6 370 1.3E-112 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_17285 0b084f99f89e8f9e716ccf022335da56 402 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 363 1.6E-125 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UA74_28320 555e7e3482a19528b665346f91be6fd0 142 SUPERFAMILY SSF46785 8 138 3.03E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_28320 555e7e3482a19528b665346f91be6fd0 142 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_28320 555e7e3482a19528b665346f91be6fd0 142 Pfam PF01047 MarR family 34 90 1.5E-17 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28320 555e7e3482a19528b665346f91be6fd0 142 SMART SM00347 26 126 4.4E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28320 555e7e3482a19528b665346f91be6fd0 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28320 555e7e3482a19528b665346f91be6fd0 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 1.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28320 555e7e3482a19528b665346f91be6fd0 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28320 555e7e3482a19528b665346f91be6fd0 142 Gene3D G3DSA:1.10.10.10 8 141 8.7E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26100 232790798cc29f77a0a749012a641b6e 347 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 12 336 1.8E-17 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_26100 232790798cc29f77a0a749012a641b6e 347 SUPERFAMILY SSF51726 65 340 2.75E-27 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_26100 232790798cc29f77a0a749012a641b6e 347 Gene3D G3DSA:3.20.20.210 80 342 6.3E-25 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_26680 82a32cf3f7462ec3a4b438177a55e101 310 Pfam PF04321 RmlD substrate binding domain 6 299 7.2E-104 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 UA74_26680 82a32cf3f7462ec3a4b438177a55e101 310 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 6 298 2.1E-85 T 12-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 UA74_26680 82a32cf3f7462ec3a4b438177a55e101 310 Gene3D G3DSA:3.40.50.720 7 287 5.0E-91 T 12-10-2018 UA74_26680 82a32cf3f7462ec3a4b438177a55e101 310 SUPERFAMILY SSF51735 6 298 7.19E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_26680 82a32cf3f7462ec3a4b438177a55e101 310 Gene3D G3DSA:3.90.25.10 173 293 5.0E-91 T 12-10-2018 UA74_18965 c2d0c959973adbf769f79992312750ef 159 Pfam PF03061 Thioesterase superfamily 32 114 8.3E-8 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 UA74_18965 c2d0c959973adbf769f79992312750ef 159 SUPERFAMILY SSF54637 15 143 3.87E-20 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_18965 c2d0c959973adbf769f79992312750ef 159 Gene3D G3DSA:3.10.129.10 8 150 3.0E-18 T 12-10-2018 UA74_05655 f8314734735ffedf9cb4deb9edccc018 490 Gene3D G3DSA:3.20.20.80 41 394 2.3E-30 T 12-10-2018 UA74_05655 f8314734735ffedf9cb4deb9edccc018 490 SUPERFAMILY SSF51445 37 398 7.39E-27 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_25740 ecc34ae26ee996b2a09c52db41a467ac 263 Pfam PF00583 Acetyltransferase (GNAT) family 61 177 9.3E-12 T 12-10-2018 IPR000182 GNAT domain UA74_25740 ecc34ae26ee996b2a09c52db41a467ac 263 SUPERFAMILY SSF55729 39 196 1.05E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_25740 ecc34ae26ee996b2a09c52db41a467ac 263 Gene3D G3DSA:3.40.630.30 39 200 1.5E-33 T 12-10-2018 UA74_16510 cf58a137dc170fe19b8f7002764fba4a 304 Pfam PF13704 Glycosyl transferase family 2 10 101 1.1E-16 T 12-10-2018 UA74_16510 cf58a137dc170fe19b8f7002764fba4a 304 SUPERFAMILY SSF53448 8 100 1.46E-7 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_15800 f259bbf7becc99c826264dff2fff1b7f 245 Pfam PF01881 CRISPR associated protein Cas6 100 243 3.5E-8 T 12-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 Gene3D G3DSA:3.60.20.40 414 598 9.3E-52 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 271 287 8.0E-68 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 498 515 8.0E-68 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 70 95 8.0E-68 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 414 432 8.0E-68 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 474 489 8.0E-68 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 162 181 8.0E-68 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 144 162 8.0E-68 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 438 456 8.0E-68 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 301 320 8.0E-68 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 Pfam PF01019 Gamma-glutamyltranspeptidase 63 593 5.3E-147 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 Gene3D G3DSA:1.10.246.130 287 402 1.2E-29 T 12-10-2018 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 50 587 1.1E-122 T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 UA74_24230 8db073318f93c3607cde7628de7c5c59 609 SUPERFAMILY SSF56235 40 597 5.18E-152 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_01550 e7efd0d2afa7e7679448951de8095845 209 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 134 144 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 UA74_01550 e7efd0d2afa7e7679448951de8095845 209 Gene3D G3DSA:3.30.1130.10 74 209 3.9E-59 T 12-10-2018 UA74_01550 e7efd0d2afa7e7679448951de8095845 209 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 24 207 41.436 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 UA74_01550 e7efd0d2afa7e7679448951de8095845 209 Gene3D G3DSA:1.10.286.10 10 72 1.7E-20 T 12-10-2018 UA74_01550 e7efd0d2afa7e7679448951de8095845 209 Pfam PF01227 GTP cyclohydrolase I 29 206 7.4E-75 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 UA74_01550 e7efd0d2afa7e7679448951de8095845 209 SUPERFAMILY SSF55620 20 207 8.15E-77 T 12-10-2018 UA74_01550 e7efd0d2afa7e7679448951de8095845 209 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 30 208 8.8E-70 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 UA74_17095 b73e2592c1a79a229f9cda5efc714bde 447 SUPERFAMILY SSF103473 20 420 1.57E-58 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_17095 b73e2592c1a79a229f9cda5efc714bde 447 Gene3D G3DSA:1.20.1250.20 18 430 1.3E-60 T 12-10-2018 UA74_17095 b73e2592c1a79a229f9cda5efc714bde 447 Pfam PF07690 Major Facilitator Superfamily 72 385 2.5E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_08830 53a1a86a45912ec25ae26d8b438207ae 79 Pfam PF13083 KH domain 6 66 8.6E-19 T 12-10-2018 UA74_08830 53a1a86a45912ec25ae26d8b438207ae 79 Hamap MF_00088 UPF0109 protein . 4 75 20.446 T 12-10-2018 IPR020627 Uncharacterised protein family UPF0109 UA74_08830 53a1a86a45912ec25ae26d8b438207ae 79 SUPERFAMILY SSF54814 18 61 1.11E-7 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 6.3E-33 T 12-10-2018 UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 6.3E-33 T 12-10-2018 UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 6.3E-33 T 12-10-2018 UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 354 6.3E-33 T 12-10-2018 UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 338 6.3E-33 T 12-10-2018 UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 Gene3D G3DSA:3.40.30.120 396 510 6.1E-31 T 12-10-2018 UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 SUPERFAMILY SSF51905 3 384 7.86E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 Pfam PF01494 FAD binding domain 3 349 1.5E-72 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 Gene3D G3DSA:3.50.50.60 6 350 1.3E-99 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_15045 67d3353f21f041fe11e775ac83c57f45 521 Gene3D G3DSA:3.30.70.2450 179 277 1.3E-99 T 12-10-2018 UA74_04575 3121be6ede63af85f54e40552e9abd67 216 SUPERFAMILY SSF53335 37 214 1.09E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_04575 3121be6ede63af85f54e40552e9abd67 216 Pfam PF01596 O-methyltransferase 40 214 4.0E-27 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 UA74_04575 3121be6ede63af85f54e40552e9abd67 216 Gene3D G3DSA:3.40.50.150 7 215 3.1E-59 T 12-10-2018 UA74_23180 c5fdf2c00a7db647431eac6dc6035ef2 272 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 29 256 4.8E-19 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 UA74_23180 c5fdf2c00a7db647431eac6dc6035ef2 272 Gene3D G3DSA:1.10.520.40 142 271 1.2E-16 T 12-10-2018 IPR038287 Cse2 superfamily UA74_23180 c5fdf2c00a7db647431eac6dc6035ef2 272 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 174 258 6.6E-12 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 UA74_23180 c5fdf2c00a7db647431eac6dc6035ef2 272 Gene3D G3DSA:1.10.520.40 9 114 5.4E-6 T 12-10-2018 IPR038287 Cse2 superfamily UA74_15725 3b3b6dbaa1f73aceb20020a56465aa00 391 SUPERFAMILY SSF48452 181 294 2.74E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_15725 3b3b6dbaa1f73aceb20020a56465aa00 391 Gene3D G3DSA:1.25.40.10 103 379 1.3E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_15725 3b3b6dbaa1f73aceb20020a56465aa00 391 Gene3D G3DSA:1.10.260.40 12 69 1.6E-8 T 12-10-2018 UA74_15725 3b3b6dbaa1f73aceb20020a56465aa00 391 Pfam PF13560 Helix-turn-helix domain 9 66 2.5E-6 T 12-10-2018 UA74_23440 a4606b4d1a478ca6dd3568cd4b4ec603 117 SUPERFAMILY SSF52091 12 100 1.39E-21 T 12-10-2018 IPR036513 STAS domain superfamily UA74_23440 a4606b4d1a478ca6dd3568cd4b4ec603 117 Gene3D G3DSA:3.30.750.24 5 105 1.2E-27 T 12-10-2018 IPR036513 STAS domain superfamily UA74_23440 a4606b4d1a478ca6dd3568cd4b4ec603 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 11 100 1.4E-23 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 UA74_23440 a4606b4d1a478ca6dd3568cd4b4ec603 117 Pfam PF13466 STAS domain 14 94 5.4E-19 T 12-10-2018 IPR002645 STAS domain UA74_05320 4ec472b10727db4f394d873e833bb57e 497 Pfam PF00561 alpha/beta hydrolase fold 93 469 5.6E-29 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_05320 4ec472b10727db4f394d873e833bb57e 497 SUPERFAMILY SSF53474 70 467 2.75E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22645 0a158acfdf7335dd78f48f7cb0378871 526 PIRSF PIRSF002741 12 523 8.7E-63 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UA74_22645 0a158acfdf7335dd78f48f7cb0378871 526 Gene3D G3DSA:3.40.190.10 48 279 9.3E-52 T 12-10-2018 UA74_22645 0a158acfdf7335dd78f48f7cb0378871 526 SUPERFAMILY SSF53850 46 514 2.9E-89 T 12-10-2018 UA74_22645 0a158acfdf7335dd78f48f7cb0378871 526 Gene3D G3DSA:3.10.105.10 280 493 6.3E-31 T 12-10-2018 UA74_22645 0a158acfdf7335dd78f48f7cb0378871 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 93 406 5.9E-65 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain UA74_28880 dcbe5c15cfbd9b376a1b5d45fbda1024 411 Pfam PF02515 CoA-transferase family III 1 360 6.8E-119 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 UA74_28880 dcbe5c15cfbd9b376a1b5d45fbda1024 411 Gene3D G3DSA:3.40.50.10540 1 377 7.7E-122 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily UA74_28880 dcbe5c15cfbd9b376a1b5d45fbda1024 411 Gene3D G3DSA:3.30.1540.10 223 314 7.7E-122 T 12-10-2018 UA74_28880 dcbe5c15cfbd9b376a1b5d45fbda1024 411 SUPERFAMILY SSF89796 1 383 4.19E-124 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily UA74_26335 41890728f7590a9aee2d252ac65829d7 295 SUPERFAMILY SSF55781 103 289 1.44E-41 T 12-10-2018 UA74_26335 41890728f7590a9aee2d252ac65829d7 295 Pfam PF09339 IclR helix-turn-helix domain 40 88 7.0E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_26335 41890728f7590a9aee2d252ac65829d7 295 Pfam PF01614 Bacterial transcriptional regulator 158 283 2.0E-16 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_26335 41890728f7590a9aee2d252ac65829d7 295 Gene3D G3DSA:3.30.450.40 112 291 9.3E-43 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_26335 41890728f7590a9aee2d252ac65829d7 295 SUPERFAMILY SSF46785 38 111 4.07E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_26335 41890728f7590a9aee2d252ac65829d7 295 Gene3D G3DSA:1.10.10.10 36 111 7.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_26335 41890728f7590a9aee2d252ac65829d7 295 SMART SM00346 38 128 3.1E-19 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_16665 54b5bbb6f550b7809797f6946c8d42a8 329 PIRSF PIRSF016838 2 322 5.3E-27 T 12-10-2018 IPR028349 Protein PafC UA74_16665 54b5bbb6f550b7809797f6946c8d42a8 329 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_16665 54b5bbb6f550b7809797f6946c8d42a8 329 Gene3D G3DSA:1.10.10.10 5 65 1.3E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16665 54b5bbb6f550b7809797f6946c8d42a8 329 Pfam PF13280 WYL domain 143 311 7.9E-30 T 12-10-2018 IPR026881 WYL domain UA74_16665 54b5bbb6f550b7809797f6946c8d42a8 329 SUPERFAMILY SSF46785 6 62 1.44E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_16665 54b5bbb6f550b7809797f6946c8d42a8 329 Pfam PF08279 HTH domain 7 58 2.1E-12 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 UA74_24470 ccf940aff1fc6c1c5cdc90a9e3accece 292 Pfam PF12158 Protein of unknown function (DUF3592) 146 247 1.4E-5 T 12-10-2018 IPR021994 Protein of unknown function DUF3592 UA74_22925 d4be601a43595a4565498943f3bc733f 788 SUPERFAMILY SSF52129 1 289 9.54E-17 T 12-10-2018 IPR029030 Caspase-like domain superfamily UA74_22925 d4be601a43595a4565498943f3bc733f 788 Pfam PF00656 Caspase domain 8 299 1.8E-21 T 12-10-2018 UA74_28480 b764905e41cd34f7e73db7c94de677a7 346 SUPERFAMILY SSF53850 59 283 9.93E-41 T 12-10-2018 UA74_28480 b764905e41cd34f7e73db7c94de677a7 346 Gene3D G3DSA:3.40.190.10 54 168 4.0E-16 T 12-10-2018 UA74_28480 b764905e41cd34f7e73db7c94de677a7 346 Gene3D G3DSA:3.40.190.10 169 343 6.5E-31 T 12-10-2018 UA74_28480 b764905e41cd34f7e73db7c94de677a7 346 Pfam PF09084 NMT1/THI5 like 73 279 5.6E-28 T 12-10-2018 IPR015168 SsuA/THI5-like UA74_28480 b764905e41cd34f7e73db7c94de677a7 346 SMART SM00062 74 296 0.002 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_01325 4a5266c1c74aa6b912dc9d3254af8fc1 141 Pfam PF00472 RF-1 domain 11 136 7.5E-25 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UA74_01325 4a5266c1c74aa6b912dc9d3254af8fc1 141 Gene3D G3DSA:3.30.160.20 5 141 2.1E-31 T 12-10-2018 UA74_01325 4a5266c1c74aa6b912dc9d3254af8fc1 141 SUPERFAMILY SSF75620 11 103 5.1E-13 T 12-10-2018 UA74_17685 3fe57e3acda6c6c9dd6c6d080581eed8 101 Gene3D G3DSA:3.30.70.240 2 78 8.4E-26 T 12-10-2018 UA74_17685 3fe57e3acda6c6c9dd6c6d080581eed8 101 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 4 89 1.5E-29 T 12-10-2018 IPR010152 CRISPR-associated protein Cas2 subtype UA74_17685 3fe57e3acda6c6c9dd6c6d080581eed8 101 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 5 89 1.7E-16 T 12-10-2018 IPR010152 CRISPR-associated protein Cas2 subtype UA74_19630 7f7112939d41a657e1066f2023fa193f 630 Pfam PF02310 B12 binding domain 122 200 1.0E-9 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_19630 7f7112939d41a657e1066f2023fa193f 630 Gene3D G3DSA:3.80.30.20 263 435 9.0E-12 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UA74_19630 7f7112939d41a657e1066f2023fa193f 630 Pfam PF04055 Radical SAM superfamily 271 429 9.9E-10 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UA74_19630 7f7112939d41a657e1066f2023fa193f 630 SUPERFAMILY SSF102114 264 488 1.77E-23 T 12-10-2018 UA74_19630 7f7112939d41a657e1066f2023fa193f 630 TIGRFAM TIGR03975 rSAM_ocin_1: ribosomal peptide maturation radical SAM protein 1 3 602 1.8E-191 T 12-10-2018 IPR023984 Ribosomal peptide maturation radical SAM protein 1 UA74_19630 7f7112939d41a657e1066f2023fa193f 630 SMART SM00729 264 477 3.0E-21 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UA74_16625 af5ef30d8c18a4d4d76d76210a71627e 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 316 4.4E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_16625 af5ef30d8c18a4d4d76d76210a71627e 323 SUPERFAMILY SSF161098 95 299 1.18E-13 T 12-10-2018 IPR035906 MetI-like superfamily UA74_16625 af5ef30d8c18a4d4d76d76210a71627e 323 Gene3D G3DSA:1.10.3720.10 92 313 2.3E-14 T 12-10-2018 IPR035906 MetI-like superfamily UA74_19450 ee5e315718a0dfa5c2453410b2f8db33 267 PIRSF PIRSF006648 1 267 4.8E-74 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_19450 ee5e315718a0dfa5c2453410b2f8db33 267 Pfam PF01061 ABC-2 type transporter 12 220 9.3E-31 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_01460 7d1a0cd636d607a21b580845c1353d2b 410 Pfam PF13177 DNA polymerase III, delta subunit 48 193 1.9E-33 T 12-10-2018 UA74_01460 7d1a0cd636d607a21b580845c1353d2b 410 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 48 228 1.9E-55 T 12-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_01460 7d1a0cd636d607a21b580845c1353d2b 410 SUPERFAMILY SSF52540 16 232 1.59E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01460 7d1a0cd636d607a21b580845c1353d2b 410 Gene3D G3DSA:3.40.50.300 11 193 1.4E-44 T 12-10-2018 UA74_25340 18ef24fffd3b213e804b3750577a7def 143 Pfam PF11253 Protein of unknown function (DUF3052) 13 137 5.1E-58 T 12-10-2018 IPR021412 Protein of unknown function DUF3052 UA74_20990 fe1ad15a766a00c7d5450f84a3869631 317 Pfam PF01636 Phosphotransferase enzyme family 72 242 8.9E-7 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_20990 fe1ad15a766a00c7d5450f84a3869631 317 SUPERFAMILY SSF56112 22 281 3.5E-17 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_13040 14c08d6471a1296f66ea9cb2201210a1 492 SUPERFAMILY SSF51905 11 476 6.29E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_13040 14c08d6471a1296f66ea9cb2201210a1 492 Pfam PF13450 NAD(P)-binding Rossmann-like domain 14 65 1.0E-9 T 12-10-2018 UA74_13040 14c08d6471a1296f66ea9cb2201210a1 492 Gene3D G3DSA:3.90.660.50 93 399 2.3E-14 T 12-10-2018 UA74_13040 14c08d6471a1296f66ea9cb2201210a1 492 Gene3D G3DSA:3.50.50.60 13 288 2.3E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_09085 b7da3b9aeb1527862590fd4a925fdaea 178 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 43 175 2.0E-37 T 12-10-2018 IPR005247 YbhB/YbcL UA74_09085 b7da3b9aeb1527862590fd4a925fdaea 178 SUPERFAMILY SSF49777 7 170 1.44E-44 T 12-10-2018 IPR036610 PEBP-like superfamily UA74_09085 b7da3b9aeb1527862590fd4a925fdaea 178 Pfam PF01161 Phosphatidylethanolamine-binding protein 34 174 2.4E-32 T 12-10-2018 IPR008914 Phosphatidylethanolamine-binding protein UA74_09085 b7da3b9aeb1527862590fd4a925fdaea 178 Gene3D G3DSA:3.90.280.10 6 177 2.8E-47 T 12-10-2018 IPR036610 PEBP-like superfamily UA74_16670 93cfd310923ce55af4ac18e41275cf5a 418 SUPERFAMILY SSF103473 17 405 1.7E-46 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_16670 93cfd310923ce55af4ac18e41275cf5a 418 Gene3D G3DSA:1.20.1250.20 15 403 1.5E-38 T 12-10-2018 UA74_16670 93cfd310923ce55af4ac18e41275cf5a 418 Pfam PF05977 Transmembrane secretion effector 17 400 1.3E-35 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_24605 1719a34f2005eced67a729307672c189 214 SUPERFAMILY SSF50800 1 209 1.15E-45 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily UA74_24605 1719a34f2005eced67a729307672c189 214 Gene3D G3DSA:2.40.33.20 1 213 6.9E-53 T 12-10-2018 UA74_24605 1719a34f2005eced67a729307672c189 214 Pfam PF03473 MOSC domain 49 161 1.2E-13 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 UA74_25480 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 UA74_25480 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 PRINTS PR00340 P-II protein signature 83 103 6.4E-30 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_25480 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 PRINTS PR00340 P-II protein signature 2 17 6.4E-30 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_25480 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 PRINTS PR00340 P-II protein signature 52 75 6.4E-30 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_25480 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 PRINTS PR00340 P-II protein signature 23 41 6.4E-30 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_25480 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.5E-32 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_25480 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 SUPERFAMILY SSF54913 2 112 3.5E-34 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta UA74_25480 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 SMART SM00938 4 105 6.0E-42 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UA74_25480 bd31aca8d9b6cb1f29cf98f2c6ff27ed 112 Gene3D G3DSA:3.30.70.120 1 112 1.7E-35 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UA74_10280 442be5461f86997d7c315927b24350d4 427 Pfam PF01270 Glycosyl hydrolases family 8 65 419 2.3E-17 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_10280 442be5461f86997d7c315927b24350d4 427 Gene3D G3DSA:1.50.10.10 65 421 4.4E-113 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_10280 442be5461f86997d7c315927b24350d4 427 SUPERFAMILY SSF48208 62 422 9.07E-73 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_10280 442be5461f86997d7c315927b24350d4 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 235 252 1.2E-20 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_10280 442be5461f86997d7c315927b24350d4 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 278 289 1.2E-20 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_10280 442be5461f86997d7c315927b24350d4 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 105 118 1.2E-20 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_10280 442be5461f86997d7c315927b24350d4 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 407 421 1.2E-20 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_10280 442be5461f86997d7c315927b24350d4 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 167 185 1.2E-20 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_10280 442be5461f86997d7c315927b24350d4 427 PRINTS PR00735 Glycosyl hydrolase family 8 signature 308 317 1.2E-20 T 12-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UA74_16895 7ce9c53421e425ff496963d79b961143 308 SMART SM00382 29 208 2.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_16895 7ce9c53421e425ff496963d79b961143 308 Gene3D G3DSA:3.40.50.300 1 228 1.7E-54 T 12-10-2018 UA74_16895 7ce9c53421e425ff496963d79b961143 308 SUPERFAMILY SSF52540 4 220 9.27E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_16895 7ce9c53421e425ff496963d79b961143 308 Pfam PF00005 ABC transporter 20 160 1.6E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_16895 7ce9c53421e425ff496963d79b961143 308 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22940 7968a49788b485f12928ada28577eea2 318 Pfam PF00248 Aldo/keto reductase family 21 316 8.9E-59 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_22940 7968a49788b485f12928ada28577eea2 318 Gene3D G3DSA:3.20.20.100 8 318 8.3E-90 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_22940 7968a49788b485f12928ada28577eea2 318 SUPERFAMILY SSF51430 9 316 4.32E-79 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_22380 9e79da3ed7ea595ee8e2dfb911725a68 445 SUPERFAMILY SSF103473 44 430 1.44E-42 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_22380 9e79da3ed7ea595ee8e2dfb911725a68 445 Gene3D G3DSA:1.20.1250.20 41 428 4.8E-39 T 12-10-2018 UA74_22380 9e79da3ed7ea595ee8e2dfb911725a68 445 Pfam PF05977 Transmembrane secretion effector 47 427 4.0E-33 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_29490 ab67fee435751e787306ada22f5953a0 390 Gene3D G3DSA:2.30.40.10 20 385 3.2E-125 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_29490 ab67fee435751e787306ada22f5953a0 390 SUPERFAMILY SSF51556 66 359 2.98E-94 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_29490 ab67fee435751e787306ada22f5953a0 390 SUPERFAMILY SSF51338 6 387 2.43E-17 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_29490 ab67fee435751e787306ada22f5953a0 390 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 16 382 2.4E-84 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 UA74_29490 ab67fee435751e787306ada22f5953a0 390 Pfam PF01979 Amidohydrolase family 62 387 3.1E-28 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_29490 ab67fee435751e787306ada22f5953a0 390 PIRSF PIRSF038994 15 390 4.1E-116 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 UA74_29490 ab67fee435751e787306ada22f5953a0 390 Gene3D G3DSA:3.20.20.140 67 353 3.2E-125 T 12-10-2018 UA74_03455 330f9ab3f70c59ab913c8fe4c29b2cb5 115 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 40 91 7.0E-11 T 12-10-2018 IPR026496 Putative ATP-grasp target RiPP UA74_02595 596f0b58ba8a3496ec1f02260215da6f 458 Pfam PF00146 NADH dehydrogenase 19 341 8.5E-125 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02595 596f0b58ba8a3496ec1f02260215da6f 458 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 223 236 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02595 596f0b58ba8a3496ec1f02260215da6f 458 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 12 348 24.923 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02595 596f0b58ba8a3496ec1f02260215da6f 458 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 58 73 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_11710 d51cfb0a3665258738f39d814d8d1c63 319 SUPERFAMILY SSF53756 8 310 6.91E-55 T 12-10-2018 UA74_11710 d51cfb0a3665258738f39d814d8d1c63 319 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 153 265 6.4E-23 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 UA74_11710 d51cfb0a3665258738f39d814d8d1c63 319 Gene3D G3DSA:3.40.50.2000 143 311 6.2E-36 T 12-10-2018 UA74_11710 d51cfb0a3665258738f39d814d8d1c63 319 Gene3D G3DSA:3.40.50.2000 9 96 7.5E-8 T 12-10-2018 UA74_08545 c33117fc2f874435a1d3c24ef189fb74 221 Gene3D G3DSA:1.10.150.240 21 87 1.3E-20 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_08545 c33117fc2f874435a1d3c24ef189fb74 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 187 2.1E-11 T 12-10-2018 UA74_08545 c33117fc2f874435a1d3c24ef189fb74 221 SUPERFAMILY SSF56784 8 214 1.63E-30 T 12-10-2018 IPR036412 HAD-like superfamily UA74_08545 c33117fc2f874435a1d3c24ef189fb74 221 Gene3D G3DSA:3.40.50.1000 9 202 1.3E-20 T 12-10-2018 IPR023214 HAD superfamily UA74_22260 dcf92b5b5a8264072d655b5393f1c26c 181 Gene3D G3DSA:2.60.120.10 4 130 2.3E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_22260 dcf92b5b5a8264072d655b5393f1c26c 181 Pfam PF07883 Cupin domain 38 90 6.0E-9 T 12-10-2018 IPR013096 Cupin 2, conserved barrel UA74_22260 dcf92b5b5a8264072d655b5393f1c26c 181 SUPERFAMILY SSF51182 6 105 1.56E-11 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_11770 451e6e7b92f27521a98140d88d29127f 239 PIRSF PIRSF008292 1 235 1.0E-89 T 12-10-2018 IPR016538 Uncharacterised conserved protein UCP008292 UA74_11770 451e6e7b92f27521a98140d88d29127f 239 Gene3D G3DSA:3.60.21.10 1 238 1.1E-18 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_11770 451e6e7b92f27521a98140d88d29127f 239 Pfam PF00149 Calcineurin-like phosphoesterase 2 204 1.9E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UA74_11770 451e6e7b92f27521a98140d88d29127f 239 SUPERFAMILY SSF56300 2 224 9.77E-31 T 12-10-2018 UA74_06315 789fdd65132a527f35929f531e31da82 130 Gene3D G3DSA:3.40.250.10 1 123 1.6E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_06315 789fdd65132a527f35929f531e31da82 130 SUPERFAMILY SSF52821 8 126 2.36E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_06315 789fdd65132a527f35929f531e31da82 130 Pfam PF00581 Rhodanese-like domain 19 116 4.2E-10 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_06315 789fdd65132a527f35929f531e31da82 130 SMART SM00450 16 120 1.2E-15 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_10450 338e703a11d75af78d8fa8f8c1addc38 220 Gene3D G3DSA:3.10.490.10 13 207 1.8E-13 T 12-10-2018 UA74_18630 fa48a20faf9c294b2e89d557f6edf902 383 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 76 118 2.1E-8 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UA74_18630 fa48a20faf9c294b2e89d557f6edf902 383 Gene3D G3DSA:1.20.1290.10 18 128 2.7E-13 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_18630 fa48a20faf9c294b2e89d557f6edf902 383 Pfam PF02627 Carboxymuconolactone decarboxylase family 61 120 3.8E-7 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UA74_18630 fa48a20faf9c294b2e89d557f6edf902 383 SUPERFAMILY SSF69118 14 179 2.75E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 UA74_17850 460287a429b443860613bb5ec154258d 690 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 39 566 4.0E-123 T 12-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 UA74_17850 460287a429b443860613bb5ec154258d 690 SUPERFAMILY SSF48208 93 393 4.17E-20 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_27475 a5e5ab25475c35c0d604c225bd91fcf7 430 Pfam PF02653 Branched-chain amino acid transport system / permease component 65 355 1.1E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_04470 2eb03f80088a4b254b0e17ff36e26d43 119 Gene3D G3DSA:1.10.10.10 7 111 7.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04470 2eb03f80088a4b254b0e17ff36e26d43 119 SUPERFAMILY SSF46785 10 112 3.64E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04470 2eb03f80088a4b254b0e17ff36e26d43 119 Pfam PF03551 Transcriptional regulator PadR-like family 21 93 6.5E-21 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_28820 297a324f9a48190d34144b404f59d2c7 345 Gene3D G3DSA:3.40.50.720 1 306 3.2E-50 T 12-10-2018 UA74_28820 297a324f9a48190d34144b404f59d2c7 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 235 6.7E-41 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_28820 297a324f9a48190d34144b404f59d2c7 345 SUPERFAMILY SSF51735 1 317 7.08E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18985 9b7232daa209700ab5520da7a7acef29 264 SUPERFAMILY SSF52540 3 224 2.24E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_18985 9b7232daa209700ab5520da7a7acef29 264 SMART SM00382 27 211 8.9E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_18985 9b7232daa209700ab5520da7a7acef29 264 Pfam PF00005 ABC transporter 20 167 7.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_18985 9b7232daa209700ab5520da7a7acef29 264 Gene3D G3DSA:3.40.50.300 2 250 9.5E-66 T 12-10-2018 UA74_09210 cfb1f30d386689a50d59954a966a3e5f 343 Gene3D G3DSA:3.40.640.10 25 269 4.2E-42 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_09210 cfb1f30d386689a50d59954a966a3e5f 343 Gene3D G3DSA:3.90.1150.10 15 337 4.2E-42 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_09210 cfb1f30d386689a50d59954a966a3e5f 343 Pfam PF00266 Aminotransferase class-V 20 290 7.7E-8 T 12-10-2018 IPR000192 Aminotransferase class V domain UA74_09210 cfb1f30d386689a50d59954a966a3e5f 343 SUPERFAMILY SSF53383 14 342 1.21E-39 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_28115 de48f5863877e40ab4df1b4fb3993f52 226 SMART SM00756 39 180 5.4E-51 T 12-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 UA74_28115 de48f5863877e40ab4df1b4fb3993f52 226 Gene3D G3DSA:1.20.1440.130 29 205 2.1E-19 T 12-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 UA74_28115 de48f5863877e40ab4df1b4fb3993f52 226 Pfam PF07884 Vitamin K epoxide reductase family 45 176 1.3E-30 T 12-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 UA74_11585 1dd6b4169a1e51d05a634f3172efe4ce 479 Pfam PF00171 Aldehyde dehydrogenase family 18 472 6.6E-130 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_11585 1dd6b4169a1e51d05a634f3172efe4ce 479 SUPERFAMILY SSF53720 7 475 1.7E-128 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_11585 1dd6b4169a1e51d05a634f3172efe4ce 479 Gene3D G3DSA:3.40.309.10 254 442 1.2E-135 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_11585 1dd6b4169a1e51d05a634f3172efe4ce 479 Gene3D G3DSA:3.40.605.10 11 470 1.2E-135 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_18360 0b976ded56a5daaf9f32d7ee5737fa25 289 SUPERFAMILY SSF51430 17 284 2.88E-75 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_18360 0b976ded56a5daaf9f32d7ee5737fa25 289 Gene3D G3DSA:3.20.20.100 17 289 1.5E-81 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_18360 0b976ded56a5daaf9f32d7ee5737fa25 289 PRINTS PR00069 Aldo-keto reductase signature 119 137 1.3E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_18360 0b976ded56a5daaf9f32d7ee5737fa25 289 PRINTS PR00069 Aldo-keto reductase signature 150 167 1.3E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_18360 0b976ded56a5daaf9f32d7ee5737fa25 289 PRINTS PR00069 Aldo-keto reductase signature 221 245 1.3E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_18360 0b976ded56a5daaf9f32d7ee5737fa25 289 PRINTS PR00069 Aldo-keto reductase signature 54 78 1.3E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_18360 0b976ded56a5daaf9f32d7ee5737fa25 289 Pfam PF00248 Aldo/keto reductase family 24 284 8.7E-61 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_13290 f464ac5a2059b5ef37a84f170e21925f 128 SUPERFAMILY SSF46785 24 115 3.87E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_13290 f464ac5a2059b5ef37a84f170e21925f 128 Pfam PF12840 Helix-turn-helix domain 37 93 6.3E-7 T 12-10-2018 UA74_13290 f464ac5a2059b5ef37a84f170e21925f 128 SMART SM00418 35 113 3.8E-18 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_13290 f464ac5a2059b5ef37a84f170e21925f 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 6.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_13290 f464ac5a2059b5ef37a84f170e21925f 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 6.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_13290 f464ac5a2059b5ef37a84f170e21925f 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 6.1E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_13290 f464ac5a2059b5ef37a84f170e21925f 128 Gene3D G3DSA:1.10.10.10 16 119 3.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_28310 3f061aff0b63406b67d52d8ac2cb757e 498 PIRSF PIRSF012666 1 498 7.3E-211 T 12-10-2018 IPR016602 Uncharacterised conserved protein UCP012666 UA74_28310 3f061aff0b63406b67d52d8ac2cb757e 498 Gene3D G3DSA:3.30.590.20 37 473 1.8E-56 T 12-10-2018 UA74_28310 3f061aff0b63406b67d52d8ac2cb757e 498 SUPERFAMILY SSF55931 40 463 3.04E-50 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UA74_13750 e5bec095d6c7dbe169e843d00271d545 211 SUPERFAMILY SSF55144 29 203 1.19E-17 T 12-10-2018 IPR009097 Cyclic phosphodiesterase UA74_13750 e5bec095d6c7dbe169e843d00271d545 211 Pfam PF13563 2'-5' RNA ligase superfamily 53 187 3.7E-15 T 12-10-2018 UA74_13750 e5bec095d6c7dbe169e843d00271d545 211 Gene3D G3DSA:3.90.1140.10 18 210 1.5E-18 T 12-10-2018 UA74_27160 32a3792a8e609de172fc19dde496b7c7 169 Pfam PF03703 Bacterial PH domain 76 154 8.4E-15 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_29945 e20889a83530b77014460a61e6ac1193 710 SUPERFAMILY SSF63829 354 621 9.16E-6 T 12-10-2018 UA74_29945 e20889a83530b77014460a61e6ac1193 710 Pfam PF05787 Bacterial protein of unknown function (DUF839) 116 666 1.6E-171 T 12-10-2018 IPR008557 Protein of unknown function DUF839 UA74_04710 0244f4acf2b191c621d958dfacaaddfe 228 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 21 200 1.7E-81 T 12-10-2018 UA74_04710 0244f4acf2b191c621d958dfacaaddfe 228 SUPERFAMILY SSF47240 23 169 1.53E-7 T 12-10-2018 IPR009078 Ferritin-like superfamily UA74_04710 0244f4acf2b191c621d958dfacaaddfe 228 Gene3D G3DSA:1.20.1260.10 12 228 4.5E-76 T 12-10-2018 IPR012347 Ferritin-like UA74_07600 a7d5fa6b4e6d412bdda546183bcaca6a 107 Gene3D G3DSA:3.30.750.24 9 107 1.8E-18 T 12-10-2018 IPR036513 STAS domain superfamily UA74_07600 a7d5fa6b4e6d412bdda546183bcaca6a 107 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 102 1.3E-15 T 12-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 UA74_07600 a7d5fa6b4e6d412bdda546183bcaca6a 107 SUPERFAMILY SSF52091 10 101 1.24E-14 T 12-10-2018 IPR036513 STAS domain superfamily UA74_07600 a7d5fa6b4e6d412bdda546183bcaca6a 107 Pfam PF01740 STAS domain 19 101 1.4E-10 T 12-10-2018 IPR002645 STAS domain UA74_06360 f2ba88f797d94e185862dccd8b5fa4af 313 Gene3D G3DSA:3.40.50.300 40 308 3.9E-54 T 12-10-2018 UA74_06360 f2ba88f797d94e185862dccd8b5fa4af 313 SUPERFAMILY SSF52540 50 288 1.91E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_06360 f2ba88f797d94e185862dccd8b5fa4af 313 Pfam PF00005 ABC transporter 71 221 2.2E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_06360 f2ba88f797d94e185862dccd8b5fa4af 313 SMART SM00382 79 262 4.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_20630 1356bdf399ccc5f35d1fbd0ae5c1fb8c 440 Gene3D G3DSA:3.20.20.70 10 352 1.2E-127 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_20630 1356bdf399ccc5f35d1fbd0ae5c1fb8c 440 SUPERFAMILY SSF51011 354 436 4.14E-7 T 12-10-2018 UA74_20630 1356bdf399ccc5f35d1fbd0ae5c1fb8c 440 Gene3D G3DSA:2.60.40.1180 354 439 6.4E-14 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta UA74_20630 1356bdf399ccc5f35d1fbd0ae5c1fb8c 440 Pfam PF16499 Alpha galactosidase A 172 351 1.2E-18 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_20630 1356bdf399ccc5f35d1fbd0ae5c1fb8c 440 SUPERFAMILY SSF51445 19 351 4.74E-66 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_20630 1356bdf399ccc5f35d1fbd0ae5c1fb8c 440 PRINTS PR00740 Glycosyl hydrolase family 27 signature 207 225 1.4E-12 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_20630 1356bdf399ccc5f35d1fbd0ae5c1fb8c 440 PRINTS PR00740 Glycosyl hydrolase family 27 signature 307 328 1.4E-12 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_20630 1356bdf399ccc5f35d1fbd0ae5c1fb8c 440 PRINTS PR00740 Glycosyl hydrolase family 27 signature 54 69 1.4E-12 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_20630 1356bdf399ccc5f35d1fbd0ae5c1fb8c 440 PRINTS PR00740 Glycosyl hydrolase family 27 signature 19 38 1.4E-12 T 12-10-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 UA74_28300 ad45293fcf6a93ed2fc5bff8b2637a82 206 Pfam PF10801 Protein of unknown function (DUF2537) 120 199 2.8E-22 T 12-10-2018 IPR024244 Protein of unknown function DUF2537 UA74_28245 9e6955f3ba4256d4db7bd37a57013483 308 SUPERFAMILY SSF74650 12 305 2.64E-57 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 UA74_28245 9e6955f3ba4256d4db7bd37a57013483 308 Pfam PF01263 Aldose 1-epimerase 15 302 2.1E-40 T 12-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 UA74_28245 9e6955f3ba4256d4db7bd37a57013483 308 Gene3D G3DSA:2.70.98.10 13 307 6.1E-74 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 UA74_01885 648533e15d72273a651892b5153ac376 98 Pfam PF11662 Protein of unknown function (DUF3263) 16 88 2.5E-33 T 12-10-2018 IPR021678 Protein of unknown function DUF3263 UA74_22965 d4fe028df7cf978505264492d5cee73c 200 Gene3D G3DSA:3.40.50.300 15 196 1.1E-15 T 12-10-2018 UA74_22965 d4fe028df7cf978505264492d5cee73c 200 SUPERFAMILY SSF52540 19 191 5.34E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22965 d4fe028df7cf978505264492d5cee73c 200 Pfam PF03029 Conserved hypothetical ATP binding protein 23 190 9.0E-24 T 12-10-2018 IPR004130 GPN-loop GTPase UA74_23200 dfd424bec700f73543c74b7c9e71214d 312 SUPERFAMILY SSF55486 99 304 3.04E-9 T 12-10-2018 UA74_09350 0bee78598f51f15844fd4d408b2d66d9 158 Gene3D G3DSA:1.10.260.40 4 96 4.8E-6 T 12-10-2018 UA74_09350 0bee78598f51f15844fd4d408b2d66d9 158 SUPERFAMILY SSF47413 21 59 3.26E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_07450 1c59a7c1634bae644e78a9381db1b9b9 270 Pfam PF00583 Acetyltransferase (GNAT) family 176 257 4.6E-6 T 12-10-2018 IPR000182 GNAT domain UA74_07450 1c59a7c1634bae644e78a9381db1b9b9 270 Gene3D G3DSA:3.40.630.30 2 270 4.2E-22 T 12-10-2018 UA74_07450 1c59a7c1634bae644e78a9381db1b9b9 270 SUPERFAMILY SSF55729 101 264 2.16E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_15310 97f6e0f791c1e5ea729f3cdcacb3c864 200 Pfam PF01872 RibD C-terminal domain 2 187 7.8E-10 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_15310 97f6e0f791c1e5ea729f3cdcacb3c864 200 SUPERFAMILY SSF53597 2 196 1.07E-26 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_15310 97f6e0f791c1e5ea729f3cdcacb3c864 200 Gene3D G3DSA:3.40.430.10 2 193 7.8E-32 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_27695 1506e8f84ddb92a51c0b1ccafbb94e57 271 Gene3D G3DSA:2.70.70.10 112 267 2.6E-43 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_27695 1506e8f84ddb92a51c0b1ccafbb94e57 271 SUPERFAMILY SSF51261 136 264 4.03E-47 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_27695 1506e8f84ddb92a51c0b1ccafbb94e57 271 Pfam PF01551 Peptidase family M23 164 260 5.9E-31 T 12-10-2018 IPR016047 Peptidase M23 UA74_24115 13d4759067a4d7f0d4f74989792725cd 306 SMART SM01130 5 304 4.6E-62 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_24115 13d4759067a4d7f0d4f74989792725cd 306 Gene3D G3DSA:3.20.20.70 3 305 5.5E-64 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_24115 13d4759067a4d7f0d4f74989792725cd 306 Pfam PF00701 Dihydrodipicolinate synthetase family 6 302 5.0E-35 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_24115 13d4759067a4d7f0d4f74989792725cd 306 PIRSF PIRSF001365 1 305 1.7E-58 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_24115 13d4759067a4d7f0d4f74989792725cd 306 SUPERFAMILY SSF51569 3 305 7.01E-63 T 12-10-2018 UA74_24115 13d4759067a4d7f0d4f74989792725cd 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 6.9E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_24115 13d4759067a4d7f0d4f74989792725cd 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 6.9E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_24115 13d4759067a4d7f0d4f74989792725cd 306 PRINTS PR00146 Dihydrodipicolinate synthase signature 136 153 6.9E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 UA74_15945 200dc0decebcf821611752072a7ba45d 189 SUPERFAMILY SSF51197 6 177 3.57E-43 T 12-10-2018 UA74_15945 200dc0decebcf821611752072a7ba45d 189 Gene3D G3DSA:2.60.120.330 5 186 1.5E-43 T 12-10-2018 IPR027443 Isopenicillin N synthase-like UA74_15945 200dc0decebcf821611752072a7ba45d 189 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 54 149 4.0E-17 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 SUPERFAMILY SSF52172 16 151 5.98E-20 T 12-10-2018 IPR011006 CheY-like superfamily UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 Pfam PF00196 Bacterial regulatory proteins, luxR family 167 212 6.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 210 9.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 198 9.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 182 9.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 Gene3D G3DSA:3.40.50.2300 18 116 8.9E-14 T 12-10-2018 UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 SMART SM00448 18 137 1.5E-10 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 Gene3D G3DSA:1.10.10.10 120 234 6.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 Pfam PF00072 Response regulator receiver domain 20 116 1.5E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 SUPERFAMILY SSF46894 149 215 3.4E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_04265 76755846fa984f3e4e6e70c4eb4ca0f2 236 SMART SM00421 165 227 8.2E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_02890 131d7fe9830aabaf2a03911668a970b3 323 Gene3D G3DSA:3.40.50.300 19 253 5.8E-61 T 12-10-2018 UA74_02890 131d7fe9830aabaf2a03911668a970b3 323 SMART SM00382 52 230 6.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_02890 131d7fe9830aabaf2a03911668a970b3 323 SUPERFAMILY SSF52540 26 251 7.44E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_02890 131d7fe9830aabaf2a03911668a970b3 323 Pfam PF00005 ABC transporter 44 181 5.3E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_02890 131d7fe9830aabaf2a03911668a970b3 323 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 270 300 0.0085 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 605 637 8.3E-7 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 Pfam PF00005 ABC transporter 398 553 1.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 Gene3D G3DSA:3.40.50.300 367 652 3.7E-84 T 12-10-2018 UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 Gene3D G3DSA:3.40.50.300 30 350 2.5E-76 T 12-10-2018 UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 ProSitePatterns PS00211 ABC transporters family signature. 526 540 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 SMART SM00382 406 603 1.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 SMART SM00382 61 268 2.4E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 SUPERFAMILY SSF52540 32 290 1.17E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 ProSitePatterns PS00211 ABC transporters family signature. 191 205 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 Pfam PF00005 ABC transporter 53 218 3.7E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_22130 149651ebc22e7acf90253411b7b38cf4 654 SUPERFAMILY SSF52540 390 625 9.27E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_15060 df559ddff29b087fc066d21514a657f9 267 Gene3D G3DSA:3.90.25.10 121 250 6.3E-56 T 12-10-2018 UA74_15060 df559ddff29b087fc066d21514a657f9 267 Pfam PF13460 NAD(P)H-binding 7 168 1.0E-13 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_15060 df559ddff29b087fc066d21514a657f9 267 Gene3D G3DSA:3.40.50.720 4 248 6.3E-56 T 12-10-2018 UA74_15060 df559ddff29b087fc066d21514a657f9 267 SUPERFAMILY SSF51735 2 224 2.67E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12605 8ab5bb9117ff5c589d483c87ec6c87b6 214 Gene3D G3DSA:3.40.50.150 57 190 5.5E-7 T 12-10-2018 UA74_12605 8ab5bb9117ff5c589d483c87ec6c87b6 214 SUPERFAMILY SSF53335 74 198 5.71E-7 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_12605 8ab5bb9117ff5c589d483c87ec6c87b6 214 Gene3D G3DSA:2.20.130.10 117 177 5.5E-7 T 12-10-2018 UA74_14405 2366040bac25aaa44fe4337a9ae22a38 631 SUPERFAMILY SSF53649 23 458 3.32E-84 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UA74_14405 2366040bac25aaa44fe4337a9ae22a38 631 SMART SM00098 38 459 1.2E-13 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_14405 2366040bac25aaa44fe4337a9ae22a38 631 Pfam PF00245 Alkaline phosphatase 38 379 2.4E-54 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_14405 2366040bac25aaa44fe4337a9ae22a38 631 Gene3D G3DSA:3.40.720.10 22 456 3.0E-98 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UA74_14405 2366040bac25aaa44fe4337a9ae22a38 631 PRINTS PR00113 Alkaline phosphatase signature 302 331 1.8E-17 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_14405 2366040bac25aaa44fe4337a9ae22a38 631 PRINTS PR00113 Alkaline phosphatase signature 37 57 1.8E-17 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_14405 2366040bac25aaa44fe4337a9ae22a38 631 PRINTS PR00113 Alkaline phosphatase signature 205 215 1.8E-17 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UA74_21885 af276f96df52394aff2678024b63ec38 287 SUPERFAMILY SSF51735 3 245 1.1E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_21885 af276f96df52394aff2678024b63ec38 287 Gene3D G3DSA:3.40.50.720 1 273 1.3E-46 T 12-10-2018 UA74_21885 af276f96df52394aff2678024b63ec38 287 Pfam PF00106 short chain dehydrogenase 7 210 2.7E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21885 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 5.6E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21885 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 210 5.6E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21885 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 191 5.6E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21885 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.6E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_21885 af276f96df52394aff2678024b63ec38 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 5.6E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22425 76651e7228757894a44185c4a6b92b5b 436 Gene3D G3DSA:3.30.50.30 3 47 4.0E-14 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily UA74_22425 76651e7228757894a44185c4a6b92b5b 436 Pfam PF07724 AAA domain (Cdc48 subfamily) 127 318 2.5E-40 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UA74_22425 76651e7228757894a44185c4a6b92b5b 436 Gene3D G3DSA:1.10.8.60 324 426 1.1E-31 T 12-10-2018 UA74_22425 76651e7228757894a44185c4a6b92b5b 436 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 325 402 3.7E-13 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_22425 76651e7228757894a44185c4a6b92b5b 436 SMART SM00994 7 47 9.5E-17 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UA74_22425 76651e7228757894a44185c4a6b92b5b 436 Gene3D G3DSA:3.40.50.300 68 322 2.3E-90 T 12-10-2018 UA74_22425 76651e7228757894a44185c4a6b92b5b 436 SUPERFAMILY SSF57716 8 44 1.18E-7 T 12-10-2018 UA74_22425 76651e7228757894a44185c4a6b92b5b 436 SMART SM00382 126 279 2.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_22425 76651e7228757894a44185c4a6b92b5b 436 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 8 419 3.0E-154 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UA74_22425 76651e7228757894a44185c4a6b92b5b 436 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 5 423 45.211 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UA74_22425 76651e7228757894a44185c4a6b92b5b 436 SUPERFAMILY SSF52540 71 411 3.02E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22425 76651e7228757894a44185c4a6b92b5b 436 SMART SM01086 325 419 6.8E-27 T 12-10-2018 IPR019489 Clp ATPase, C-terminal UA74_22425 76651e7228757894a44185c4a6b92b5b 436 Pfam PF06689 ClpX C4-type zinc finger 9 45 1.0E-15 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UA74_21530 cd10e5a192103eafa86b828d13c1c128 344 Pfam PF11382 Copper transport outer membrane protein, MctB 2 308 6.9E-84 T 12-10-2018 IPR021522 Copper transporter MctB GO:0016020|GO:0055070 UA74_22805 b0a68b40b99c71cad7bf4af50cdb485f 197 Gene3D G3DSA:3.40.1410.10 25 191 7.4E-43 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_22805 b0a68b40b99c71cad7bf4af50cdb485f 197 SMART SM00866 48 188 2.2E-23 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_22805 b0a68b40b99c71cad7bf4af50cdb485f 197 SUPERFAMILY SSF64288 57 193 2.75E-33 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_22805 b0a68b40b99c71cad7bf4af50cdb485f 197 Pfam PF07702 UTRA domain 59 187 1.3E-29 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UA74_11375 7cd45e94e209b6f448b7e065970990bb 224 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 79 101 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_11375 7cd45e94e209b6f448b7e065970990bb 224 PIRSF PIRSF000847 32 218 3.0E-43 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 UA74_11375 7cd45e94e209b6f448b7e065970990bb 224 Pfam PF01066 CDP-alcohol phosphatidyltransferase 37 101 4.4E-15 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_11375 7cd45e94e209b6f448b7e065970990bb 224 Gene3D G3DSA:1.20.120.1760 33 181 8.5E-12 T 12-10-2018 UA74_06730 9171466cb115b0603e77eee3a06094f4 493 Pfam PF08309 LVIVD repeat 92 122 0.023 T 12-10-2018 IPR013211 LVIVD UA74_06730 9171466cb115b0603e77eee3a06094f4 493 SUPERFAMILY SSF75011 170 459 1.03E-8 T 12-10-2018 UA74_05370 f3c55bbfb6fc68c9a4c8e06cb6ac6a3f 296 Gene3D G3DSA:3.40.50.720 7 295 6.6E-66 T 12-10-2018 UA74_05370 f3c55bbfb6fc68c9a4c8e06cb6ac6a3f 296 Pfam PF05368 NmrA-like family 7 243 4.6E-41 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 UA74_05370 f3c55bbfb6fc68c9a4c8e06cb6ac6a3f 296 SUPERFAMILY SSF51735 5 291 1.23E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_08800 482c560639f460a99d6f9c463275ce4c 1082 Pfam PF13569 Domain of unknown function (DUF4132) 837 970 5.6E-31 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 UA74_23290 a92c9da9e5bf577a94184a510672fa3e 258 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 1 201 6.9E-38 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UA74_14290 c0c33500f6ca69194895e911d203a482 334 SUPERFAMILY SSF53335 22 215 4.14E-13 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_14290 c0c33500f6ca69194895e911d203a482 334 Gene3D G3DSA:3.40.50.150 16 216 9.8E-11 T 12-10-2018 UA74_14290 c0c33500f6ca69194895e911d203a482 334 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 50 324 1.6E-83 T 12-10-2018 IPR015324 Ribosomal protein Rsm22-like GO:0006412|GO:0008168 UA74_08185 6341da0a8ef8575a69de64ce1c42a21a 222 Gene3D G3DSA:3.40.50.300 17 198 1.7E-11 T 12-10-2018 UA74_08185 6341da0a8ef8575a69de64ce1c42a21a 222 SUPERFAMILY SSF52540 63 196 5.96E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_02580 bd77ee003798a5edbed023e48c1e6401 265 SUPERFAMILY SSF52833 40 199 3.47E-43 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_02580 bd77ee003798a5edbed023e48c1e6401 265 PIRSF PIRSF000216 20 250 3.4E-61 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02580 bd77ee003798a5edbed023e48c1e6401 265 Gene3D G3DSA:3.40.30.10 106 210 1.7E-20 T 12-10-2018 UA74_02580 bd77ee003798a5edbed023e48c1e6401 265 Gene3D G3DSA:1.10.10.1590 35 105 1.6E-20 T 12-10-2018 UA74_02580 bd77ee003798a5edbed023e48c1e6401 265 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 46 191 1.6E-44 T 12-10-2018 UA74_30135 cf0c12c7f028cc0ae81b2af72961cc12 190 Pfam PF08044 Domain of unknown function (DUF1707) 15 67 1.4E-17 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 UA74_14515 ccb8744e98a8d1bb8f42d54c69fdfc8e 361 Gene3D G3DSA:3.40.50.1970 1 159 2.1E-45 T 12-10-2018 UA74_14515 ccb8744e98a8d1bb8f42d54c69fdfc8e 361 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 335 9.9E-76 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 UA74_14515 ccb8744e98a8d1bb8f42d54c69fdfc8e 361 SUPERFAMILY SSF56796 7 349 2.22E-86 T 12-10-2018 UA74_14515 ccb8744e98a8d1bb8f42d54c69fdfc8e 361 Gene3D G3DSA:1.20.1090.10 160 351 4.5E-55 T 12-10-2018 UA74_02645 49e292ae12fafdc6c966f4d26e142e21 353 Gene3D G3DSA:3.40.50.970 95 234 2.1E-27 T 12-10-2018 UA74_02645 49e292ae12fafdc6c966f4d26e142e21 353 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 70 217 4.2E-30 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UA74_02645 49e292ae12fafdc6c966f4d26e142e21 353 SUPERFAMILY SSF52518 28 350 5.16E-84 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_07750 c4bd8be9555823f4c2f2be94941ec2bd 349 Gene3D G3DSA:2.40.110.10 100 182 9.7E-10 T 12-10-2018 UA74_07750 c4bd8be9555823f4c2f2be94941ec2bd 349 SUPERFAMILY SSF56645 31 187 1.55E-14 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UA74_07750 c4bd8be9555823f4c2f2be94941ec2bd 349 SUPERFAMILY SSF47203 187 328 2.44E-9 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UA74_07750 c4bd8be9555823f4c2f2be94941ec2bd 349 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 187 324 1.1E-6 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UA74_07750 c4bd8be9555823f4c2f2be94941ec2bd 349 Gene3D G3DSA:1.20.140.10 183 348 8.3E-9 T 12-10-2018 UA74_23760 1963804f9f8028dd3ea5f2cdd1ac0afe 147 Gene3D G3DSA:3.30.70.2010 18 138 1.9E-5 T 12-10-2018 UA74_18900 5a2ae20ae79fac278a04e5efe25c14a3 122 Pfam PF12680 SnoaL-like domain 9 110 1.0E-12 T 12-10-2018 IPR037401 SnoaL-like domain UA74_18900 5a2ae20ae79fac278a04e5efe25c14a3 122 Gene3D G3DSA:3.10.450.50 2 120 1.1E-40 T 12-10-2018 UA74_18900 5a2ae20ae79fac278a04e5efe25c14a3 122 SUPERFAMILY SSF54427 1 117 2.1E-34 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_19490 b7bca7b148ed83ea9f794e17be4cbe62 429 SUPERFAMILY SSF103473 30 418 9.29E-49 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_19490 b7bca7b148ed83ea9f794e17be4cbe62 429 Pfam PF07690 Major Facilitator Superfamily 50 327 3.5E-23 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_19490 b7bca7b148ed83ea9f794e17be4cbe62 429 Gene3D G3DSA:1.20.1250.20 38 414 6.5E-39 T 12-10-2018 UA74_18185 eef2cd3aed22132d70d5230c2f56a265 528 Pfam PF01391 Collagen triple helix repeat (20 copies) 387 445 1.2E-8 T 12-10-2018 IPR008160 Collagen triple helix repeat UA74_18185 eef2cd3aed22132d70d5230c2f56a265 528 Gene3D G3DSA:1.50.10.20 193 336 7.8E-13 T 12-10-2018 UA74_18185 eef2cd3aed22132d70d5230c2f56a265 528 SUPERFAMILY SSF48239 137 322 1.69E-17 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UA74_12150 587bb062b43ced7d8ea60b2d847b4f8e 300 SUPERFAMILY SSF54593 167 296 1.69E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_12150 587bb062b43ced7d8ea60b2d847b4f8e 300 Gene3D G3DSA:3.10.180.10 164 293 1.2E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_12150 587bb062b43ced7d8ea60b2d847b4f8e 300 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 171 273 1.9E-8 T 12-10-2018 UA74_12150 587bb062b43ced7d8ea60b2d847b4f8e 300 Pfam PF13302 Acetyltransferase (GNAT) domain 8 145 2.0E-16 T 12-10-2018 IPR000182 GNAT domain UA74_12150 587bb062b43ced7d8ea60b2d847b4f8e 300 SUPERFAMILY SSF55729 1 150 1.79E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_12150 587bb062b43ced7d8ea60b2d847b4f8e 300 Gene3D G3DSA:3.40.630.30 1 156 1.8E-29 T 12-10-2018 UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 Gene3D G3DSA:3.30.300.50 121 194 1.6E-7 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 Gene3D G3DSA:3.30.300.50 38 115 1.4E-9 T 12-10-2018 IPR035070 Streptogrisin prodomain UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 Pfam PF02983 Alpha-lytic protease prodomain 123 179 3.2E-12 T 12-10-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 SUPERFAMILY SSF54806 140 189 4.97E-5 T 12-10-2018 IPR037295 Alpha-lytic protease prodomain UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 Gene3D G3DSA:2.40.10.10 203 380 3.4E-72 T 12-10-2018 UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 Gene3D G3DSA:2.40.10.10 271 369 3.4E-72 T 12-10-2018 UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 SUPERFAMILY SSF50494 207 375 9.24E-33 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 PIRSF PIRSF001134 2 384 1.3E-125 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 304 321 1.2E-42 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 323 346 1.2E-42 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 223 237 1.2E-42 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 347 361 1.2E-42 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01960 ba95b8c8f00505d29e5ae8c77f1421d1 384 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 283 303 1.2E-42 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_24385 d2b53995df4097aeffe78793784bb95a 241 SUPERFAMILY SSF63817 84 236 1.29E-10 T 12-10-2018 IPR023365 Sortase domain superfamily UA74_24385 d2b53995df4097aeffe78793784bb95a 241 Gene3D G3DSA:2.40.260.10 64 240 3.1E-14 T 12-10-2018 IPR023365 Sortase domain superfamily UA74_24385 d2b53995df4097aeffe78793784bb95a 241 Pfam PF04203 Sortase family 136 234 8.0E-9 T 12-10-2018 IPR005754 Sortase family UA74_11145 56e275fe5e51760f76ea8247979ff129 439 Pfam PF01494 FAD binding domain 109 335 4.0E-5 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_11145 56e275fe5e51760f76ea8247979ff129 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.5E-5 T 12-10-2018 UA74_11145 56e275fe5e51760f76ea8247979ff129 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 1.5E-5 T 12-10-2018 UA74_11145 56e275fe5e51760f76ea8247979ff129 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 318 1.5E-5 T 12-10-2018 UA74_11145 56e275fe5e51760f76ea8247979ff129 439 SUPERFAMILY SSF51905 3 370 1.15E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_11145 56e275fe5e51760f76ea8247979ff129 439 Gene3D G3DSA:3.50.50.60 3 378 2.8E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_08155 4dc7d98a3a9eb42166a9a376d999985b 284 Pfam PF01061 ABC-2 type transporter 38 246 1.4E-19 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_08155 4dc7d98a3a9eb42166a9a376d999985b 284 PIRSF PIRSF006648 10 282 4.3E-24 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_08155 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 226 245 4.6E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_08155 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 133 158 4.6E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_08155 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 170 194 4.6E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_08155 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 4.6E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_08155 4dc7d98a3a9eb42166a9a376d999985b 284 PRINTS PR00164 ABC-2 type transport system membrane protein signature 53 74 4.6E-18 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_27195 a802668acac3429576bbe1fae0eae7d8 181 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 37 158 1.5E-28 T 12-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein UA74_04305 a33d66a648a9df23ff1950ab3591b32d 147 SUPERFAMILY SSF55811 3 134 2.3E-11 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_04305 a33d66a648a9df23ff1950ab3591b32d 147 Gene3D G3DSA:3.90.79.10 1 104 2.2E-8 T 12-10-2018 UA74_04305 a33d66a648a9df23ff1950ab3591b32d 147 Pfam PF00293 NUDIX domain 4 87 4.3E-6 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_06950 a4b8ce25430e95147b4dd901f18fd5a6 295 Pfam PF03713 Domain of unknown function (DUF305) 121 283 2.0E-46 T 12-10-2018 IPR005183 Domain of unknown function DUF305 UA74_06950 a4b8ce25430e95147b4dd901f18fd5a6 295 Gene3D G3DSA:1.20.1260.10 114 287 4.9E-59 T 12-10-2018 IPR012347 Ferritin-like UA74_26400 a40a2d655ffcfaab945b65312e717dcc 302 Gene3D G3DSA:3.40.50.1820 40 290 1.8E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26400 a40a2d655ffcfaab945b65312e717dcc 302 Pfam PF07859 alpha/beta hydrolase fold 81 198 1.2E-14 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 UA74_26400 a40a2d655ffcfaab945b65312e717dcc 302 SUPERFAMILY SSF53474 31 275 4.33E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20310 5c8a3a6a7a836f9046aac4b0a9b5154a 495 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 367 376 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_20310 5c8a3a6a7a836f9046aac4b0a9b5154a 495 PRINTS PR00359 B-class P450 signature 365 374 3.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20310 5c8a3a6a7a836f9046aac4b0a9b5154a 495 PRINTS PR00359 B-class P450 signature 173 189 3.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20310 5c8a3a6a7a836f9046aac4b0a9b5154a 495 PRINTS PR00359 B-class P450 signature 127 138 3.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20310 5c8a3a6a7a836f9046aac4b0a9b5154a 495 PRINTS PR00359 B-class P450 signature 374 385 3.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20310 5c8a3a6a7a836f9046aac4b0a9b5154a 495 PRINTS PR00359 B-class P450 signature 224 246 3.3E-9 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20310 5c8a3a6a7a836f9046aac4b0a9b5154a 495 Gene3D G3DSA:1.10.630.10 35 432 3.9E-79 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20310 5c8a3a6a7a836f9046aac4b0a9b5154a 495 SUPERFAMILY SSF48264 45 427 2.49E-58 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_24560 a70670a77787aedc89adc7f37c16bf94 304 SUPERFAMILY SSF161098 96 284 6.67E-30 T 12-10-2018 IPR035906 MetI-like superfamily UA74_24560 a70670a77787aedc89adc7f37c16bf94 304 Gene3D G3DSA:1.10.3720.10 97 294 5.3E-27 T 12-10-2018 IPR035906 MetI-like superfamily UA74_24560 a70670a77787aedc89adc7f37c16bf94 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 286 3.0E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_20240 1b86593495defa39347eb0e36c79fc86 293 Pfam PF13460 NAD(P)H-binding 10 189 3.1E-30 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_20240 1b86593495defa39347eb0e36c79fc86 293 SUPERFAMILY SSF51735 6 244 3.17E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_20240 1b86593495defa39347eb0e36c79fc86 293 Gene3D G3DSA:3.90.25.10 141 273 6.2E-72 T 12-10-2018 UA74_20240 1b86593495defa39347eb0e36c79fc86 293 Gene3D G3DSA:3.40.50.720 7 271 6.2E-72 T 12-10-2018 UA74_07265 fda68c14be5dba5fbb98007ec3472a03 209 Gene3D G3DSA:3.40.50.720 1 207 7.9E-48 T 12-10-2018 UA74_07265 fda68c14be5dba5fbb98007ec3472a03 209 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 97 1.0E-12 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UA74_07265 fda68c14be5dba5fbb98007ec3472a03 209 SUPERFAMILY SSF51735 1 202 1.62E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12505 7b7312c2ef03f2b483dd1d15fd900f13 328 Gene3D G3DSA:3.40.50.300 11 254 7.5E-63 T 12-10-2018 UA74_12505 7b7312c2ef03f2b483dd1d15fd900f13 328 Pfam PF00005 ABC transporter 44 182 2.4E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_12505 7b7312c2ef03f2b483dd1d15fd900f13 328 SUPERFAMILY SSF52540 17 245 6.95E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_12505 7b7312c2ef03f2b483dd1d15fd900f13 328 SMART SM00382 52 230 4.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_12505 7b7312c2ef03f2b483dd1d15fd900f13 328 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_15355 de90433aee24b2741ade64150158d40f 408 Gene3D G3DSA:1.20.1250.20 207 399 1.8E-14 T 12-10-2018 UA74_15355 de90433aee24b2741ade64150158d40f 408 Pfam PF07690 Major Facilitator Superfamily 9 329 1.7E-36 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_15355 de90433aee24b2741ade64150158d40f 408 Gene3D G3DSA:1.20.1250.20 3 184 1.7E-26 T 12-10-2018 UA74_15355 de90433aee24b2741ade64150158d40f 408 SUPERFAMILY SSF103473 3 395 3.66E-51 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_03370 4cd215e2bf322fa42c9ffeda0592d1ee 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.5E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03370 4cd215e2bf322fa42c9ffeda0592d1ee 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03370 4cd215e2bf322fa42c9ffeda0592d1ee 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.9E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03370 4cd215e2bf322fa42c9ffeda0592d1ee 201 Gene3D G3DSA:1.10.357.10 6 193 4.3E-35 T 12-10-2018 UA74_03370 4cd215e2bf322fa42c9ffeda0592d1ee 201 SUPERFAMILY SSF46689 8 76 1.2E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_05960 7d15322ca89274c02a9ead5c8db19159 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 3.4E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_19775 1d5374fc4beeee4a2780ab0094fc36b9 173 Pfam PF04542 Sigma-70 region 2 16 80 1.7E-7 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_19775 1d5374fc4beeee4a2780ab0094fc36b9 173 SUPERFAMILY SSF88946 6 91 1.41E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_19775 1d5374fc4beeee4a2780ab0094fc36b9 173 Gene3D G3DSA:1.10.1740.10 3 82 5.8E-7 T 12-10-2018 UA74_19775 1d5374fc4beeee4a2780ab0094fc36b9 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 168 4.5E-15 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UA74_19775 1d5374fc4beeee4a2780ab0094fc36b9 173 Gene3D G3DSA:1.10.10.10 96 170 4.1E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_19775 1d5374fc4beeee4a2780ab0094fc36b9 173 SUPERFAMILY SSF88659 106 168 2.06E-8 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UA74_28050 b252947da6430db7af4bc2b24e9aa753 105 Gene3D G3DSA:1.10.287.1060 7 104 6.4E-17 T 12-10-2018 UA74_28050 b252947da6430db7af4bc2b24e9aa753 105 SUPERFAMILY SSF140453 7 98 7.06E-17 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_28050 b252947da6430db7af4bc2b24e9aa753 105 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 7 92 1.3E-16 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like UA74_28050 b252947da6430db7af4bc2b24e9aa753 105 Pfam PF06013 Proteins of 100 residues with WXG 7 88 2.8E-13 T 12-10-2018 IPR010310 Type VII secretion system ESAT-6-like UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 Pfam PF00931 NB-ARC domain 314 492 1.1E-8 T 12-10-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207|Reactome: R-HSA-8953750 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 PRINTS PR00364 Disease resistance protein signature 316 331 9.9E-10 T 12-10-2018 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 PRINTS PR00364 Disease resistance protein signature 477 491 9.9E-10 T 12-10-2018 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 PRINTS PR00364 Disease resistance protein signature 392 406 9.9E-10 T 12-10-2018 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 SUPERFAMILY SSF48452 101 264 8.53E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 SUPERFAMILY SSF46894 4 95 8.79E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 SUPERFAMILY SSF52540 280 493 5.35E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 Gene3D G3DSA:1.25.40.10 101 269 7.6E-45 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 Pfam PF03704 Bacterial transcriptional activator domain 103 248 5.1E-43 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 Gene3D G3DSA:3.40.50.300 272 433 7.2E-27 T 12-10-2018 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 Gene3D G3DSA:1.10.10.10 1 99 3.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 82 3.5E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 SMART SM00862 17 96 1.1E-6 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UA74_10840 189695b3c2c51378afd34b2eb94e74ac 669 SMART SM01043 103 248 1.3E-46 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain UA74_19280 50681e3993e3cee15b01e77d674e3b21 334 Gene3D G3DSA:3.40.50.1820 26 331 4.5E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19280 50681e3993e3cee15b01e77d674e3b21 334 Pfam PF00756 Putative esterase 73 330 1.6E-55 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 UA74_19280 50681e3993e3cee15b01e77d674e3b21 334 SUPERFAMILY SSF53474 60 327 9.7E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15495 4761e623a8ad026d27a72dfc7e451e76 383 SUPERFAMILY SSF56601 17 328 5.05E-55 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_15495 4761e623a8ad026d27a72dfc7e451e76 383 Pfam PF00144 Beta-lactamase 29 325 1.4E-49 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_15495 4761e623a8ad026d27a72dfc7e451e76 383 Gene3D G3DSA:3.40.710.10 6 346 4.9E-65 T 12-10-2018 UA74_15185 ca15c5ff4d60ab353bca3a0b5478151c 496 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 166 181 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site UA74_15185 ca15c5ff4d60ab353bca3a0b5478151c 496 SUPERFAMILY SSF53474 4 488 4.47E-96 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15185 ca15c5ff4d60ab353bca3a0b5478151c 496 Pfam PF00135 Carboxylesterase family 4 451 4.3E-77 T 12-10-2018 IPR002018 Carboxylesterase, type B UA74_15185 ca15c5ff4d60ab353bca3a0b5478151c 496 Gene3D G3DSA:3.40.50.1820 3 488 4.7E-115 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15765 fcb322de7ebedbc2037884c30196c646 303 SUPERFAMILY SSF51735 4 290 3.13E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_15765 fcb322de7ebedbc2037884c30196c646 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 218 1.4E-40 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_15765 fcb322de7ebedbc2037884c30196c646 303 Gene3D G3DSA:3.40.50.720 4 278 1.6E-64 T 12-10-2018 UA74_15765 fcb322de7ebedbc2037884c30196c646 303 Gene3D G3DSA:3.90.25.10 163 288 1.6E-64 T 12-10-2018 UA74_06670 2a24f9661056ecd981a066493f3f3134 217 SMART SM00479 4 179 1.3E-30 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_06670 2a24f9661056ecd981a066493f3f3134 217 Hamap MF_00045 Oligoribonuclease [orn]. 1 180 38.926 T 12-10-2018 IPR022894 Oligoribonuclease GO:0000175 UA74_06670 2a24f9661056ecd981a066493f3f3134 217 SUPERFAMILY SSF53098 3 178 5.88E-45 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_06670 2a24f9661056ecd981a066493f3f3134 217 Gene3D G3DSA:3.30.420.10 1 182 2.2E-71 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_06670 2a24f9661056ecd981a066493f3f3134 217 Pfam PF00929 Exonuclease 6 169 3.0E-30 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UA74_00640 d19f11897a5b48a11d4c791fcfd1da87 315 Pfam PF08282 haloacid dehalogenase-like hydrolase 52 311 1.2E-50 T 12-10-2018 UA74_00640 d19f11897a5b48a11d4c791fcfd1da87 315 Gene3D G3DSA:3.40.50.1000 50 312 2.3E-55 T 12-10-2018 IPR023214 HAD superfamily UA74_00640 d19f11897a5b48a11d4c791fcfd1da87 315 Gene3D G3DSA:3.30.1240.10 130 240 2.3E-55 T 12-10-2018 UA74_00640 d19f11897a5b48a11d4c791fcfd1da87 315 SUPERFAMILY SSF56784 48 315 3.74E-59 T 12-10-2018 IPR036412 HAD-like superfamily UA74_14945 78f20a25920d37d4dd0f5e5fa24954ae 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 3.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14945 78f20a25920d37d4dd0f5e5fa24954ae 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 3.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14945 78f20a25920d37d4dd0f5e5fa24954ae 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 3.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14945 78f20a25920d37d4dd0f5e5fa24954ae 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 3.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14945 78f20a25920d37d4dd0f5e5fa24954ae 152 SUPERFAMILY SSF46785 12 138 1.92E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14945 78f20a25920d37d4dd0f5e5fa24954ae 152 Gene3D G3DSA:1.10.10.10 1 141 3.5E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14945 78f20a25920d37d4dd0f5e5fa24954ae 152 SMART SM00347 27 126 2.0E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14945 78f20a25920d37d4dd0f5e5fa24954ae 152 Pfam PF13463 Winged helix DNA-binding domain 34 99 3.2E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_09125 7b61e904d0ecd3c07cceda7b41963f4d 369 SMART SM00020 86 301 2.1E-8 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_09125 7b61e904d0ecd3c07cceda7b41963f4d 369 Gene3D G3DSA:2.40.10.10 95 297 2.5E-35 T 12-10-2018 UA74_09125 7b61e904d0ecd3c07cceda7b41963f4d 369 Pfam PF00089 Trypsin 93 300 1.2E-24 T 12-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UA74_09125 7b61e904d0ecd3c07cceda7b41963f4d 369 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 251 263 5.1E-8 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_09125 7b61e904d0ecd3c07cceda7b41963f4d 369 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 110 125 5.1E-8 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_09125 7b61e904d0ecd3c07cceda7b41963f4d 369 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 167 181 5.1E-8 T 12-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 UA74_09125 7b61e904d0ecd3c07cceda7b41963f4d 369 Gene3D G3DSA:2.40.10.10 93 295 2.5E-35 T 12-10-2018 UA74_09125 7b61e904d0ecd3c07cceda7b41963f4d 369 SUPERFAMILY SSF50494 93 305 2.26E-36 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_23190 3eff044b5a058bdc73084c7790fa041c 255 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 223 9.5E-47 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_23190 3eff044b5a058bdc73084c7790fa041c 255 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 225 9.5E-55 T 12-10-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 UA74_23190 3eff044b5a058bdc73084c7790fa041c 255 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 42 7.9E-11 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_23990 1ddee2dbbdc8f82b277ee3cbb64be431 262 SUPERFAMILY SSF53167 23 249 5.5E-42 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 UA74_23990 1ddee2dbbdc8f82b277ee3cbb64be431 262 Pfam PF01048 Phosphorylase superfamily 28 232 4.4E-24 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UA74_23990 1ddee2dbbdc8f82b277ee3cbb64be431 262 Gene3D G3DSA:3.40.50.1580 10 258 5.7E-52 T 12-10-2018 UA74_19735 f796a0f4db1b1d1bc386c4b2dcfb231f 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 2.2E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_27290 3da5acee58b059bc134055e9791c90fe 295 SMART SM00530 24 79 5.5E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_27290 3da5acee58b059bc134055e9791c90fe 295 Pfam PF13560 Helix-turn-helix domain 20 71 3.0E-12 T 12-10-2018 UA74_27290 3da5acee58b059bc134055e9791c90fe 295 Gene3D G3DSA:1.10.260.40 5 85 8.6E-12 T 12-10-2018 UA74_27290 3da5acee58b059bc134055e9791c90fe 295 SUPERFAMILY SSF47413 15 71 2.42E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_15645 7a894a6cc547ae5b7437040bac9ea870 117 SUPERFAMILY SSF51182 16 116 2.51E-10 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_15645 7a894a6cc547ae5b7437040bac9ea870 117 Gene3D G3DSA:2.60.120.10 26 112 1.2E-7 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_01160 0da301d2706505874ba9eb4f5b0d64b4 320 Gene3D G3DSA:3.60.21.10 46 257 6.2E-13 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like UA74_01160 0da301d2706505874ba9eb4f5b0d64b4 320 SUPERFAMILY SSF56300 43 284 3.07E-25 T 12-10-2018 UA74_01160 0da301d2706505874ba9eb4f5b0d64b4 320 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 48 234 4.3E-9 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 UA74_27775 dd5cf2aa1424ca78915b207c486bfff8 233 Gene3D G3DSA:3.40.50.10320 1 231 3.8E-67 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_27775 dd5cf2aa1424ca78915b207c486bfff8 233 Pfam PF02585 GlcNAc-PI de-N-acetylase 1 129 8.5E-32 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UA74_27775 dd5cf2aa1424ca78915b207c486bfff8 233 SUPERFAMILY SSF102588 1 228 9.02E-48 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UA74_05735 33430b2029bd533e5ad3abd65c801b17 242 SUPERFAMILY SSF55469 10 241 4.23E-29 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_05735 33430b2029bd533e5ad3abd65c801b17 242 Gene3D G3DSA:3.40.109.10 6 231 1.3E-34 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UA74_05735 33430b2029bd533e5ad3abd65c801b17 242 Pfam PF00881 Nitroreductase family 18 217 1.8E-19 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UA74_20360 0d712bb519d6f7d47af1de47c77ba7f0 497 Gene3D G3DSA:1.20.1250.20 43 435 9.3E-42 T 12-10-2018 UA74_20360 0d712bb519d6f7d47af1de47c77ba7f0 497 SUPERFAMILY SSF103473 47 438 7.46E-46 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_20360 0d712bb519d6f7d47af1de47c77ba7f0 497 Pfam PF05977 Transmembrane secretion effector 49 430 1.4E-39 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_06745 d59983b326001b39dbbdcde61bbc5830 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 322 8.0E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_06745 d59983b326001b39dbbdcde61bbc5830 326 Gene3D G3DSA:1.10.3720.10 77 326 3.0E-71 T 12-10-2018 IPR035906 MetI-like superfamily UA74_06745 d59983b326001b39dbbdcde61bbc5830 326 SUPERFAMILY SSF161098 81 313 2.62E-61 T 12-10-2018 IPR035906 MetI-like superfamily UA74_06740 87e23c87069bc0fa340389c24351c9dc 425 Pfam PF13416 Bacterial extracellular solute-binding protein 52 355 5.8E-27 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_06740 87e23c87069bc0fa340389c24351c9dc 425 Gene3D G3DSA:3.40.190.10 147 413 8.4E-64 T 12-10-2018 UA74_06740 87e23c87069bc0fa340389c24351c9dc 425 Gene3D G3DSA:3.40.190.10 52 353 8.4E-64 T 12-10-2018 UA74_06740 87e23c87069bc0fa340389c24351c9dc 425 SUPERFAMILY SSF53850 33 422 1.76E-48 T 12-10-2018 UA74_03285 49f0c5457a7f3e7658b886ca948fd0a3 213 SUPERFAMILY SSF55729 21 191 3.81E-37 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_03285 49f0c5457a7f3e7658b886ca948fd0a3 213 Pfam PF13302 Acetyltransferase (GNAT) domain 24 168 3.0E-13 T 12-10-2018 IPR000182 GNAT domain UA74_03285 49f0c5457a7f3e7658b886ca948fd0a3 213 Gene3D G3DSA:3.40.630.30 20 196 7.4E-40 T 12-10-2018 UA74_00895 c623aa34033f21a8f7bc84362f70005c 130 SUPERFAMILY SSF55729 20 110 3.09E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_00895 c623aa34033f21a8f7bc84362f70005c 130 Gene3D G3DSA:3.40.630.30 13 118 6.3E-20 T 12-10-2018 UA74_00895 c623aa34033f21a8f7bc84362f70005c 130 Pfam PF00583 Acetyltransferase (GNAT) family 26 106 9.8E-14 T 12-10-2018 IPR000182 GNAT domain UA74_14370 db757939d0f829ea01e6f419fdfc5332 1313 SUPERFAMILY SSF54909 43 379 8.76E-31 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_14370 db757939d0f829ea01e6f419fdfc5332 1313 SUPERFAMILY SSF51998 536 1305 1.05E-100 T 12-10-2018 UA74_14370 db757939d0f829ea01e6f419fdfc5332 1313 Pfam PF02901 Pyruvate formate lyase-like 571 1122 6.2E-126 T 12-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 UA74_14370 db757939d0f829ea01e6f419fdfc5332 1313 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 44 379 2.2E-31 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 UA74_14370 db757939d0f829ea01e6f419fdfc5332 1313 Gene3D G3DSA:3.20.70.20 556 1306 7.0E-190 T 12-10-2018 UA74_14370 db757939d0f829ea01e6f419fdfc5332 1313 Pfam PF04261 Dyp-type peroxidase family 142 377 1.3E-11 T 12-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 UA74_00595 14c878ada1c147459abbfac72b6b5236 116 SUPERFAMILY SSF55486 3 115 8.61E-40 T 12-10-2018 UA74_00595 14c878ada1c147459abbfac72b6b5236 116 Gene3D G3DSA:3.30.2010.20 1 115 1.4E-42 T 12-10-2018 IPR038555 Zincin-like metallopeptidase superfamily UA74_00595 14c878ada1c147459abbfac72b6b5236 116 Pfam PF06262 Zincin-like metallopeptidase 29 115 8.5E-34 T 12-10-2018 IPR010428 Zincin-like metallopeptidase UA74_02250 5651ce0d65e23cfda01d9697ba7098d0 300 SUPERFAMILY SSF51658 21 292 1.02E-40 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_02250 5651ce0d65e23cfda01d9697ba7098d0 300 Gene3D G3DSA:3.20.20.150 17 293 2.2E-40 T 12-10-2018 UA74_02250 5651ce0d65e23cfda01d9697ba7098d0 300 Pfam PF01261 Xylose isomerase-like TIM barrel 37 244 3.3E-12 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_21095 77b11d61ad7f1f608fac1532ea1736d4 247 Pfam PF01553 Acyltransferase 23 149 5.8E-29 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_21095 77b11d61ad7f1f608fac1532ea1736d4 247 SUPERFAMILY SSF69593 14 205 1.83E-35 T 12-10-2018 UA74_21095 77b11d61ad7f1f608fac1532ea1736d4 247 SMART SM00563 38 152 1.5E-33 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UA74_26060 f83b3ec5a578b17a69b4ae80c0168fe1 372 PIRSF PIRSF034888 1 371 4.7E-48 T 12-10-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 UA74_26060 f83b3ec5a578b17a69b4ae80c0168fe1 372 SUPERFAMILY SSF52540 1 312 3.43E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_26060 f83b3ec5a578b17a69b4ae80c0168fe1 372 Pfam PF12476 Protein of unknown function (DUF3696) 325 370 1.7E-13 T 12-10-2018 IPR022532 Domain of unknown function DUF3696, C-terminal UA74_26060 f83b3ec5a578b17a69b4ae80c0168fe1 372 Pfam PF13175 AAA ATPase domain 244 309 3.2E-12 T 12-10-2018 UA74_26060 f83b3ec5a578b17a69b4ae80c0168fe1 372 Gene3D G3DSA:3.40.50.300 1 120 1.0E-8 T 12-10-2018 UA74_19575 486ad0d98df600857628f429e227002c 119 SUPERFAMILY SSF54593 1 115 5.92E-12 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_19575 486ad0d98df600857628f429e227002c 119 Gene3D G3DSA:3.10.180.10 1 118 2.7E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_03640 48e319ded2060c9a0c4077917721f528 579 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 403 560 3.5E-39 T 12-10-2018 IPR000160 GGDEF domain UA74_03640 48e319ded2060c9a0c4077917721f528 579 Gene3D G3DSA:3.30.70.270 392 561 5.1E-48 T 12-10-2018 UA74_03640 48e319ded2060c9a0c4077917721f528 579 Pfam PF00990 Diguanylate cyclase, GGDEF domain 406 556 4.0E-38 T 12-10-2018 IPR000160 GGDEF domain UA74_03640 48e319ded2060c9a0c4077917721f528 579 SUPERFAMILY SSF55073 411 559 1.94E-40 T 12-10-2018 IPR029787 Nucleotide cyclase UA74_03640 48e319ded2060c9a0c4077917721f528 579 SMART SM00267 395 561 8.5E-47 T 12-10-2018 IPR000160 GGDEF domain UA74_05340 14f62fb873112097b33827c745451790 314 SUPERFAMILY SSF51735 13 221 9.41E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_05340 14f62fb873112097b33827c745451790 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 3.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05340 14f62fb873112097b33827c745451790 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 3.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05340 14f62fb873112097b33827c745451790 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 3.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05340 14f62fb873112097b33827c745451790 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 3.9E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05340 14f62fb873112097b33827c745451790 314 Gene3D G3DSA:3.40.50.720 7 313 3.1E-65 T 12-10-2018 UA74_05340 14f62fb873112097b33827c745451790 314 Pfam PF00106 short chain dehydrogenase 16 217 7.1E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_04970 b1358bf6ad32e232488a713d1dfbeb18 71 Gene3D G3DSA:1.10.10.10 11 71 3.5E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_14015 4a7bf2cd7a81d39e4350beaa6e909be8 265 SUPERFAMILY SSF53335 12 248 1.21E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_14015 4a7bf2cd7a81d39e4350beaa6e909be8 265 PIRSF PIRSF017393 1 264 2.7E-92 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_14015 4a7bf2cd7a81d39e4350beaa6e909be8 265 Gene3D G3DSA:3.40.50.150 2 263 2.6E-101 T 12-10-2018 UA74_14015 4a7bf2cd7a81d39e4350beaa6e909be8 265 Pfam PF04672 S-adenosyl methyltransferase 8 263 1.3E-87 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_07350 348bc7a33fef2a3fb8ba46f4adcf5b08 361 Gene3D G3DSA:3.20.20.210 8 359 5.8E-74 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_07350 348bc7a33fef2a3fb8ba46f4adcf5b08 361 SUPERFAMILY SSF51726 9 354 1.2E-49 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UA74_07350 348bc7a33fef2a3fb8ba46f4adcf5b08 361 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 10 328 3.8E-13 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UA74_08090 faf73ee67873224111e64db8588c2fdf 201 Pfam PF06821 Serine hydrolase 6 184 6.6E-26 T 12-10-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 UA74_08090 faf73ee67873224111e64db8588c2fdf 201 SUPERFAMILY SSF53474 5 186 2.48E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_08090 faf73ee67873224111e64db8588c2fdf 201 Gene3D G3DSA:3.40.50.1820 1 187 1.8E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22860 605b6e1ea52e43c0788236e2e44209d6 600 SUPERFAMILY SSF52266 177 345 4.37E-19 T 12-10-2018 UA74_22860 605b6e1ea52e43c0788236e2e44209d6 600 Gene3D G3DSA:3.40.50.1110 169 349 2.7E-15 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_22860 605b6e1ea52e43c0788236e2e44209d6 600 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 179 335 3.3E-13 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain UA74_14655 37b98b324c66628d98f60b334ca5574d 211 Gene3D G3DSA:3.40.430.10 1 197 3.2E-40 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_14655 37b98b324c66628d98f60b334ca5574d 211 Pfam PF01872 RibD C-terminal domain 4 191 8.0E-21 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_14655 37b98b324c66628d98f60b334ca5574d 211 SUPERFAMILY SSF53597 2 197 6.17E-25 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_01515 17dde9aa7624c1c0ff34c6d629514dc3 353 Gene3D G3DSA:1.20.150.30 14 135 1.1E-21 T 12-10-2018 UA74_01515 17dde9aa7624c1c0ff34c6d629514dc3 353 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 14 352 7.3E-119 T 12-10-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated UA74_01515 17dde9aa7624c1c0ff34c6d629514dc3 353 Pfam PF10103 Zincin-like metallopeptidase 14 348 3.1E-103 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 UA74_01515 17dde9aa7624c1c0ff34c6d629514dc3 353 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 14 352 5.9E-99 T 12-10-2018 IPR018766 Zinicin-like metallopeptidase type 2 UA74_01515 17dde9aa7624c1c0ff34c6d629514dc3 353 SUPERFAMILY SSF55486 13 351 3.66E-93 T 12-10-2018 UA74_00495 b162595d86a25ec5f3171d1a813e52b8 491 Pfam PF13245 AAA domain 23 271 3.0E-9 T 12-10-2018 UA74_00495 b162595d86a25ec5f3171d1a813e52b8 491 SUPERFAMILY SSF52540 15 470 2.17E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00495 b162595d86a25ec5f3171d1a813e52b8 491 Gene3D G3DSA:3.40.50.300 291 485 8.7E-22 T 12-10-2018 UA74_02205 dc579eae624552e8761b3c517e67fd19 312 Gene3D G3DSA:3.40.50.720 67 310 4.3E-59 T 12-10-2018 UA74_02205 dc579eae624552e8761b3c517e67fd19 312 SUPERFAMILY SSF51735 71 299 8.15E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_02205 dc579eae624552e8761b3c517e67fd19 312 Pfam PF00106 short chain dehydrogenase 73 249 2.8E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_02205 dc579eae624552e8761b3c517e67fd19 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 202 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_02205 dc579eae624552e8761b3c517e67fd19 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 231 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_02205 dc579eae624552e8761b3c517e67fd19 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 250 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_02205 dc579eae624552e8761b3c517e67fd19 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 90 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_02205 dc579eae624552e8761b3c517e67fd19 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 149 3.8E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_22105 c5968951917a06b1fb4642af4a3b0435 156 Gene3D G3DSA:1.20.1260.50 1 154 2.0E-49 T 12-10-2018 UA74_18010 32d4eea3278fcab9d27cd53bfdc5f431 317 SUPERFAMILY SSF53474 9 300 6.84E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18010 32d4eea3278fcab9d27cd53bfdc5f431 317 Pfam PF00561 alpha/beta hydrolase fold 30 138 2.6E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_18010 32d4eea3278fcab9d27cd53bfdc5f431 317 Gene3D G3DSA:3.40.50.1820 8 302 2.3E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16770 ebc08c8f49fee2f67ca8d22200fb5d12 233 SUPERFAMILY SSF140453 89 170 2.22E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_16770 ebc08c8f49fee2f67ca8d22200fb5d12 233 Gene3D G3DSA:1.10.287.1060 79 173 7.0E-6 T 12-10-2018 UA74_10715 f6dda3108ef39093bc881ff46f7a00dc 329 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 319 4.8E-116 T 12-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 UA74_10715 f6dda3108ef39093bc881ff46f7a00dc 329 Pfam PF03741 Integral membrane protein TerC family 70 273 1.2E-50 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 SUPERFAMILY SSF46894 148 215 5.78E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 210 2.3E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 Pfam PF00072 Response regulator receiver domain 8 119 4.9E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 2.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 2.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 2.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 SUPERFAMILY SSF52172 6 123 6.97E-29 T 12-10-2018 IPR011006 CheY-like superfamily UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 SMART SM00421 153 210 1.6E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 Gene3D G3DSA:3.40.50.12740 6 215 8.6E-58 T 12-10-2018 UA74_30130 3c700907305bc63e1d59e3f4c787f031 218 SMART SM00448 6 118 5.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_21115 bdf3f4ece6eaf0eefb95c924e8096acd 279 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 4 279 50.168 T 12-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UA74_21115 bdf3f4ece6eaf0eefb95c924e8096acd 279 PIRSF PIRSF006625 4 279 4.9E-114 T 12-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UA74_21115 bdf3f4ece6eaf0eefb95c924e8096acd 279 Gene3D G3DSA:2.60.120.520 33 145 1.8E-110 T 12-10-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UA74_21115 bdf3f4ece6eaf0eefb95c924e8096acd 279 Gene3D G3DSA:2.60.120.10 13 264 1.8E-110 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_21115 bdf3f4ece6eaf0eefb95c924e8096acd 279 SUPERFAMILY SSF51182 4 263 2.67E-91 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_21115 bdf3f4ece6eaf0eefb95c924e8096acd 279 Pfam PF04962 KduI/IolB family 40 273 2.4E-29 T 12-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UA74_20015 f9f3e0f4b5f5b58cf8e0a739e5c27b89 289 Pfam PF05448 Acetyl xylan esterase (AXE1) 3 233 1.6E-16 T 12-10-2018 IPR008391 Acetyl xylan esterase UA74_20015 f9f3e0f4b5f5b58cf8e0a739e5c27b89 289 Gene3D G3DSA:3.40.50.1820 1 269 1.8E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20015 f9f3e0f4b5f5b58cf8e0a739e5c27b89 289 SUPERFAMILY SSF53474 20 276 4.25E-14 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_29135 cd89874c3677c058f01ac7e3b65f632a 159 SUPERFAMILY SSF52833 50 152 9.72E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_29135 cd89874c3677c058f01ac7e3b65f632a 159 Pfam PF00085 Thioredoxin 67 148 1.0E-6 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 UA74_29135 cd89874c3677c058f01ac7e3b65f632a 159 Gene3D G3DSA:3.40.30.10 46 152 1.5E-9 T 12-10-2018 UA74_18325 043bae096304272077346d7506d9e6c3 361 Gene3D G3DSA:3.40.50.2300 76 333 1.2E-82 T 12-10-2018 UA74_18325 043bae096304272077346d7506d9e6c3 361 Gene3D G3DSA:3.40.50.2300 179 317 1.2E-82 T 12-10-2018 UA74_18325 043bae096304272077346d7506d9e6c3 361 SUPERFAMILY SSF53822 73 354 3.61E-68 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_18325 043bae096304272077346d7506d9e6c3 361 Pfam PF13407 Periplasmic binding protein domain 75 335 3.0E-53 T 12-10-2018 IPR025997 Periplasmic binding protein UA74_22715 aa10fcd6a5f600a5e34be1085594d90e 136 Gene3D G3DSA:3.30.1330.40 9 136 1.8E-40 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_22715 aa10fcd6a5f600a5e34be1085594d90e 136 SUPERFAMILY SSF55298 5 135 4.71E-37 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_22715 aa10fcd6a5f600a5e34be1085594d90e 136 Pfam PF01042 Endoribonuclease L-PSP 11 133 2.2E-30 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UA74_01710 083e52de6b8431e2581d4d9938e9214d 65 SUPERFAMILY SSF46955 9 57 5.37E-9 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_01710 083e52de6b8431e2581d4d9938e9214d 65 Pfam PF12728 Helix-turn-helix domain 10 55 3.5E-11 T 12-10-2018 UA74_10045 bc79acadab170e151b60b9b625ec58a8 417 Gene3D G3DSA:3.40.50.1100 28 224 2.7E-185 T 12-10-2018 UA74_10045 bc79acadab170e151b60b9b625ec58a8 417 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 20 409 52.745 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_10045 bc79acadab170e151b60b9b625ec58a8 417 Gene3D G3DSA:3.40.50.1100 72 402 2.7E-185 T 12-10-2018 UA74_10045 bc79acadab170e151b60b9b625ec58a8 417 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 72 395 2.0E-50 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_10045 bc79acadab170e151b60b9b625ec58a8 417 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 25 406 3.6E-183 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_10045 bc79acadab170e151b60b9b625ec58a8 417 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 99 113 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_10045 bc79acadab170e151b60b9b625ec58a8 417 SUPERFAMILY SSF53686 21 408 4.06E-147 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_10045 bc79acadab170e151b60b9b625ec58a8 417 PIRSF PIRSF001413 11 414 5.7E-160 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UA74_26915 c9ac52b4acc335ba199eb51d826deda6 364 Gene3D G3DSA:3.10.310.10 157 337 4.8E-102 T 12-10-2018 UA74_26915 c9ac52b4acc335ba199eb51d826deda6 364 Gene3D G3DSA:3.10.310.10 1 348 4.8E-102 T 12-10-2018 UA74_26915 c9ac52b4acc335ba199eb51d826deda6 364 SUPERFAMILY SSF54506 1 158 4.0E-48 T 12-10-2018 UA74_26915 c9ac52b4acc335ba199eb51d826deda6 364 SUPERFAMILY SSF54506 162 354 3.3E-43 T 12-10-2018 UA74_26915 c9ac52b4acc335ba199eb51d826deda6 364 Pfam PF04303 PrpF protein 1 350 2.0E-94 T 12-10-2018 IPR007400 PrpF protein UA74_26375 a5e080e376e62cd1c8de6f72f537eb60 555 SUPERFAMILY SSF53335 177 301 4.31E-14 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_26375 a5e080e376e62cd1c8de6f72f537eb60 555 Pfam PF01861 Protein of unknown function DUF43 132 304 4.5E-29 T 12-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal UA74_26375 a5e080e376e62cd1c8de6f72f537eb60 555 Gene3D G3DSA:3.40.50.150 119 326 4.4E-56 T 12-10-2018 UA74_26375 a5e080e376e62cd1c8de6f72f537eb60 555 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 235 241 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_02135 47632de0b9d425c33e18061926fa712d 390 SUPERFAMILY SSF102114 28 140 7.06E-6 T 12-10-2018 UA74_14005 a5aadaa8d766e248c576e23d334e898d 131 Pfam PF00583 Acetyltransferase (GNAT) family 24 121 3.8E-10 T 12-10-2018 IPR000182 GNAT domain UA74_14005 a5aadaa8d766e248c576e23d334e898d 131 Gene3D G3DSA:3.40.630.30 7 130 3.1E-18 T 12-10-2018 UA74_14005 a5aadaa8d766e248c576e23d334e898d 131 SUPERFAMILY SSF55729 13 125 1.18E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_08330 e1d1ca361214dbe64087bdb17d0026ce 127 SUPERFAMILY SSF54593 14 116 7.52E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_08330 e1d1ca361214dbe64087bdb17d0026ce 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 108 1.7E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_08330 e1d1ca361214dbe64087bdb17d0026ce 127 Gene3D G3DSA:3.10.180.10 8 115 2.5E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_23630 81a9a4083d0575159bbc3c60b0f77501 356 Gene3D G3DSA:3.40.50.300 16 203 4.0E-16 T 12-10-2018 UA74_23630 81a9a4083d0575159bbc3c60b0f77501 356 Pfam PF03969 AFG1-like ATPase 36 226 1.2E-39 T 12-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 UA74_23630 81a9a4083d0575159bbc3c60b0f77501 356 Pfam PF03969 AFG1-like ATPase 235 336 3.4E-15 T 12-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 UA74_23630 81a9a4083d0575159bbc3c60b0f77501 356 SUPERFAMILY SSF52540 61 244 5.58E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_04060 8890b6a9d56165ee6020108983642813 119 Gene3D G3DSA:3.20.20.30 1 119 1.2E-7 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_04060 8890b6a9d56165ee6020108983642813 119 SUPERFAMILY SSF51679 2 118 1.58E-9 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_12975 c3be373616a6c83b1f4c3a00a67e4967 216 Pfam PF08241 Methyltransferase domain 32 125 1.3E-16 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_12975 c3be373616a6c83b1f4c3a00a67e4967 216 Gene3D G3DSA:3.40.50.150 11 136 1.1E-27 T 12-10-2018 UA74_12975 c3be373616a6c83b1f4c3a00a67e4967 216 SUPERFAMILY SSF53335 10 133 1.99E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_08540 e302a95580238b1afe5593f3e0a5a338 189 Pfam PF02631 RecX family 53 172 1.8E-28 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 UA74_08540 e302a95580238b1afe5593f3e0a5a338 189 Hamap MF_01114 Regulatory protein RecX [recX]. 11 177 15.859 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 UA74_08540 e302a95580238b1afe5593f3e0a5a338 189 Gene3D G3DSA:1.10.10.10 76 121 1.1E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_08540 e302a95580238b1afe5593f3e0a5a338 189 Gene3D G3DSA:1.10.10.2800 23 75 2.1E-6 T 12-10-2018 UA74_08070 028f9e9239d02c4cc4697aca17289331 210 Gene3D G3DSA:3.90.226.10 3 200 6.8E-72 T 12-10-2018 UA74_08070 028f9e9239d02c4cc4697aca17289331 210 SUPERFAMILY SSF52096 24 199 6.93E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UA74_08070 028f9e9239d02c4cc4697aca17289331 210 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 117 130 - T 12-10-2018 IPR033135 ClpP, histidine active site UA74_08070 028f9e9239d02c4cc4697aca17289331 210 Pfam PF00574 Clp protease 23 197 1.1E-77 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA UA74_08070 028f9e9239d02c4cc4697aca17289331 210 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 6 198 39.751 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08070 028f9e9239d02c4cc4697aca17289331 210 PRINTS PR00127 Clp protease catalytic subunit P signature 173 192 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08070 028f9e9239d02c4cc4697aca17289331 210 PRINTS PR00127 Clp protease catalytic subunit P signature 24 39 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08070 028f9e9239d02c4cc4697aca17289331 210 PRINTS PR00127 Clp protease catalytic subunit P signature 64 84 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08070 028f9e9239d02c4cc4697aca17289331 210 PRINTS PR00127 Clp protease catalytic subunit P signature 95 112 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_08070 028f9e9239d02c4cc4697aca17289331 210 PRINTS PR00127 Clp protease catalytic subunit P signature 116 135 1.3E-46 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UA74_27070 e1868b7f7fc3e23da31481e202a8c48e 290 Pfam PF01040 UbiA prenyltransferase family 30 170 1.0E-16 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 UA74_27070 e1868b7f7fc3e23da31481e202a8c48e 290 Gene3D G3DSA:1.10.357.140 14 161 1.8E-11 T 12-10-2018 UA74_11735 8452bead4c671e29101f357951d72d98 212 Gene3D G3DSA:3.30.530.20 2 140 1.2E-35 T 12-10-2018 IPR023393 START-like domain superfamily UA74_11735 8452bead4c671e29101f357951d72d98 212 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 123 2.8E-17 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 UA74_11735 8452bead4c671e29101f357951d72d98 212 SUPERFAMILY SSF55961 3 142 5.5E-26 T 12-10-2018 UA74_14700 c8df0fe64fdc4eb8da909c1f7a4e148e 266 Pfam PF00535 Glycosyl transferase family 2 20 188 4.2E-33 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UA74_14700 c8df0fe64fdc4eb8da909c1f7a4e148e 266 SUPERFAMILY SSF53448 15 236 2.05E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_14700 c8df0fe64fdc4eb8da909c1f7a4e148e 266 Gene3D G3DSA:3.90.550.10 3 259 2.1E-54 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_07250 641f34bcdb26622d0f2c358195294645 492 Pfam PF04228 Putative neutral zinc metallopeptidase 136 271 2.7E-6 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative UA74_05850 3a254f236165ce82d2bc2c777b023fc7 170 Gene3D G3DSA:3.40.50.720 22 118 8.3E-27 T 12-10-2018 UA74_05850 3a254f236165ce82d2bc2c777b023fc7 170 Gene3D G3DSA:3.90.25.10 4 119 8.3E-27 T 12-10-2018 UA74_05850 3a254f236165ce82d2bc2c777b023fc7 170 SUPERFAMILY SSF51735 14 123 1.83E-13 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_05810 507946ba6de6b60d5ba98631b19cba03 225 Gene3D G3DSA:3.40.50.150 1 216 4.8E-59 T 12-10-2018 UA74_05810 507946ba6de6b60d5ba98631b19cba03 225 SUPERFAMILY SSF53335 23 143 5.93E-13 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_05810 507946ba6de6b60d5ba98631b19cba03 225 Pfam PF13649 Methyltransferase domain 28 102 3.1E-6 T 12-10-2018 UA74_02485 f638f4abf98a7627becc219cc72010a0 404 ProSitePatterns PS00455 Putative AMP-binding domain signature. 67 78 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_02485 f638f4abf98a7627becc219cc72010a0 404 Pfam PF13193 AMP-binding enzyme C-terminal domain 307 382 1.4E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_02485 f638f4abf98a7627becc219cc72010a0 404 Gene3D G3DSA:3.40.50.12780 20 290 8.3E-52 T 12-10-2018 UA74_02485 f638f4abf98a7627becc219cc72010a0 404 Pfam PF00501 AMP-binding enzyme 48 297 8.1E-38 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_02485 f638f4abf98a7627becc219cc72010a0 404 Gene3D G3DSA:3.30.300.30 291 397 5.1E-20 T 12-10-2018 UA74_02485 f638f4abf98a7627becc219cc72010a0 404 SUPERFAMILY SSF56801 36 395 6.28E-76 T 12-10-2018 UA74_07620 ec749d3e303b98961fb53aa67dcc7aa7 132 Gene3D G3DSA:1.10.287.1080 1 108 2.3E-32 T 12-10-2018 UA74_07620 ec749d3e303b98961fb53aa67dcc7aa7 132 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 103 2.4E-7 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core UA74_07620 ec749d3e303b98961fb53aa67dcc7aa7 132 SUPERFAMILY SSF101386 10 116 4.3E-28 T 12-10-2018 UA74_07620 ec749d3e303b98961fb53aa67dcc7aa7 132 PIRSF PIRSF029826 1 121 7.4E-35 T 12-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 UA74_06615 b5eb6eccb18471eac27ab093fcfc379f 271 Gene3D G3DSA:3.40.50.1820 14 238 5.3E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06615 b5eb6eccb18471eac27ab093fcfc379f 271 SUPERFAMILY SSF53474 12 222 2.13E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_06615 b5eb6eccb18471eac27ab093fcfc379f 271 Pfam PF01764 Lipase (class 3) 75 208 2.1E-30 T 12-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 UA74_13045 a96dd8bd716c80d2d45507f30f99ecad 241 SUPERFAMILY SSF52266 29 233 4.93E-35 T 12-10-2018 UA74_13045 a96dd8bd716c80d2d45507f30f99ecad 241 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 42 223 9.8E-18 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain UA74_13045 a96dd8bd716c80d2d45507f30f99ecad 241 Gene3D G3DSA:3.40.50.1110 37 241 9.2E-67 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_11050 59cad30e897425ba5cc1883e5c481d63 476 Pfam PF00289 Biotin carboxylase, N-terminal domain 15 122 1.7E-41 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_11050 59cad30e897425ba5cc1883e5c481d63 476 SUPERFAMILY SSF52440 9 125 6.76E-45 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UA74_11050 59cad30e897425ba5cc1883e5c481d63 476 Pfam PF02785 Biotin carboxylase C-terminal domain 348 457 1.1E-36 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_11050 59cad30e897425ba5cc1883e5c481d63 476 SUPERFAMILY SSF51246 343 458 5.76E-38 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UA74_11050 59cad30e897425ba5cc1883e5c481d63 476 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.3E-70 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UA74_11050 59cad30e897425ba5cc1883e5c481d63 476 Gene3D G3DSA:3.30.470.130 5 462 1.1E-181 T 12-10-2018 UA74_11050 59cad30e897425ba5cc1883e5c481d63 476 SMART SM00878 348 456 1.3E-58 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UA74_11050 59cad30e897425ba5cc1883e5c481d63 476 SUPERFAMILY SSF56059 96 362 4.42E-67 T 12-10-2018 UA74_18795 2bef0bc086c27d12e8c99ea5abd16fb9 205 SUPERFAMILY SSF46785 4 173 1.51E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18795 2bef0bc086c27d12e8c99ea5abd16fb9 205 Pfam PF03551 Transcriptional regulator PadR-like family 8 80 7.9E-8 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_18795 2bef0bc086c27d12e8c99ea5abd16fb9 205 Gene3D G3DSA:1.10.10.10 1 100 1.5E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17040 0ac371cb3ad3cdab974adcbd257f73f7 305 SUPERFAMILY SSF161098 96 287 4.06E-26 T 12-10-2018 IPR035906 MetI-like superfamily UA74_17040 0ac371cb3ad3cdab974adcbd257f73f7 305 Gene3D G3DSA:1.10.3720.10 91 305 2.1E-22 T 12-10-2018 IPR035906 MetI-like superfamily UA74_17040 0ac371cb3ad3cdab974adcbd257f73f7 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 303 1.9E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_06265 eb777ab31a84b8ead70f17810363eefd 161 PIRSF PIRSF000239 2 155 3.4E-19 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_06265 eb777ab31a84b8ead70f17810363eefd 161 Gene3D G3DSA:3.40.30.10 7 156 3.9E-46 T 12-10-2018 UA74_06265 eb777ab31a84b8ead70f17810363eefd 161 Pfam PF00578 AhpC/TSA family 10 137 9.5E-36 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UA74_06265 eb777ab31a84b8ead70f17810363eefd 161 SUPERFAMILY SSF52833 6 155 1.98E-46 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_27000 9713f08653c8897acff0e86a61386a4c 292 Pfam PF13560 Helix-turn-helix domain 14 75 3.2E-12 T 12-10-2018 UA74_27000 9713f08653c8897acff0e86a61386a4c 292 SMART SM00530 18 72 4.0E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_27000 9713f08653c8897acff0e86a61386a4c 292 SUPERFAMILY SSF47413 11 70 2.76E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_27000 9713f08653c8897acff0e86a61386a4c 292 Gene3D G3DSA:1.10.260.40 4 74 1.1E-11 T 12-10-2018 UA74_20545 0991a662b4f27eb2c58ad8432c24a5fc 697 SUPERFAMILY SSF52540 238 693 9.56E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_20545 0991a662b4f27eb2c58ad8432c24a5fc 697 Pfam PF13245 AAA domain 255 483 6.9E-18 T 12-10-2018 UA74_20545 0991a662b4f27eb2c58ad8432c24a5fc 697 Gene3D G3DSA:3.40.50.300 504 697 2.3E-33 T 12-10-2018 UA74_20545 0991a662b4f27eb2c58ad8432c24a5fc 697 Pfam PF13361 UvrD-like helicase C-terminal domain 615 686 2.4E-12 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UA74_04825 4d926d72158a5da0f11679355cc1922c 353 Pfam PF04235 Protein of unknown function (DUF418) 194 343 6.4E-30 T 12-10-2018 IPR007349 Domain of unknown function DUF418 UA74_19955 c6aa7cdd48549c330fa327c958541635 143 SUPERFAMILY SSF54593 5 142 4.95E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_19955 c6aa7cdd48549c330fa327c958541635 143 Gene3D G3DSA:3.10.180.10 2 143 3.5E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_12520 92670f7cbc4785798391a66c1c60a5be 489 SUPERFAMILY SSF101960 55 486 3.27E-140 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily UA74_12520 92670f7cbc4785798391a66c1c60a5be 489 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 33 480 5.2E-219 T 12-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 UA74_12520 92670f7cbc4785798391a66c1c60a5be 489 Pfam PF01458 Uncharacterized protein family (UPF0051) 235 460 1.7E-76 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 UA74_23325 00747eda9c044848eb0899bf71be62e2 651 Gene3D G3DSA:2.60.40.10 49 140 2.9E-24 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_23325 00747eda9c044848eb0899bf71be62e2 651 SUPERFAMILY SSF69318 152 422 1.44E-12 T 12-10-2018 UA74_11405 d7ad733a4054b31fc38703dbbcffc6cc 973 Gene3D G3DSA:3.40.640.10 538 761 1.8E-59 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_11405 d7ad733a4054b31fc38703dbbcffc6cc 973 Gene3D G3DSA:3.40.640.10 110 370 4.3E-101 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_11405 d7ad733a4054b31fc38703dbbcffc6cc 973 Gene3D G3DSA:3.90.1150.10 781 920 8.9E-37 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_11405 d7ad733a4054b31fc38703dbbcffc6cc 973 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 22 971 24.955 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UA74_11405 d7ad733a4054b31fc38703dbbcffc6cc 973 Pfam PF02347 Glycine cleavage system P-protein 461 750 5.8E-13 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UA74_11405 d7ad733a4054b31fc38703dbbcffc6cc 973 Pfam PF02347 Glycine cleavage system P-protein 30 456 3.2E-169 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UA74_11405 d7ad733a4054b31fc38703dbbcffc6cc 973 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 31 965 0.0 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UA74_11405 d7ad733a4054b31fc38703dbbcffc6cc 973 SUPERFAMILY SSF53383 476 967 8.11E-97 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_11405 d7ad733a4054b31fc38703dbbcffc6cc 973 SUPERFAMILY SSF53383 31 456 3.97E-99 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_19555 ca7866de7aee69ad391a0fe962d5280a 344 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 264 277 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_19555 ca7866de7aee69ad391a0fe962d5280a 344 Gene3D G3DSA:3.40.1190.20 15 325 2.6E-67 T 12-10-2018 IPR029056 Ribokinase-like UA74_19555 ca7866de7aee69ad391a0fe962d5280a 344 Pfam PF00294 pfkB family carbohydrate kinase 16 311 6.8E-44 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_19555 ca7866de7aee69ad391a0fe962d5280a 344 SUPERFAMILY SSF53613 15 315 2.03E-63 T 12-10-2018 IPR029056 Ribokinase-like UA74_25990 50d9f918d84714a9a112f6ce60b0e569 184 Pfam PF07681 DoxX 29 110 5.8E-16 T 12-10-2018 IPR032808 DoxX family UA74_18205 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 Gene3D G3DSA:3.50.50.60 4 322 8.6E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_18205 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 7.3E-12 T 12-10-2018 UA74_18205 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 135 150 7.3E-12 T 12-10-2018 UA74_18205 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 252 267 7.3E-12 T 12-10-2018 UA74_18205 c14aa71297ff9c2dc7eb5ffa0a909dd6 345 SUPERFAMILY SSF51905 5 311 1.61E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_16345 c5c89fcafbf02701e3cfe9fcd43507ca 155 Pfam PF08388 Group II intron, maturase-specific domain 56 131 2.1E-12 T 12-10-2018 IPR013597 Group II intron, maturase-specific UA74_12025 12ee9cf17f18f80ebdac41b67332d0ed 602 Gene3D G3DSA:1.10.510.40 378 561 1.1E-10 T 12-10-2018 UA74_12025 12ee9cf17f18f80ebdac41b67332d0ed 602 Pfam PF06276 Ferric iron reductase FhuF-like transporter 413 574 1.6E-29 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain UA74_12025 12ee9cf17f18f80ebdac41b67332d0ed 602 Pfam PF04183 IucA / IucC family 155 385 5.0E-56 T 12-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 UA74_18065 9eb6a9b22a18229b9f290c269129cb5c 364 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 16 336 7.5E-68 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 UA74_18065 9eb6a9b22a18229b9f290c269129cb5c 364 Gene3D G3DSA:3.20.20.70 4 364 4.0E-115 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_18065 9eb6a9b22a18229b9f290c269129cb5c 364 SUPERFAMILY SSF51395 1 358 8.9E-102 T 12-10-2018 UA74_26505 75b4f18161e562f35582b7f4057a8d25 141 Gene3D G3DSA:3.40.50.1000 3 134 2.5E-29 T 12-10-2018 IPR023214 HAD superfamily UA74_26505 75b4f18161e562f35582b7f4057a8d25 141 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 37 107 9.3E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_26505 75b4f18161e562f35582b7f4057a8d25 141 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 18 116 7.4E-17 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UA74_26505 75b4f18161e562f35582b7f4057a8d25 141 Pfam PF13419 Haloacid dehalogenase-like hydrolase 56 112 1.9E-8 T 12-10-2018 UA74_26505 75b4f18161e562f35582b7f4057a8d25 141 SUPERFAMILY SSF56784 6 126 1.36E-23 T 12-10-2018 IPR036412 HAD-like superfamily UA74_05720 1cf9dd572458f2eebcc54ca22fc9cd66 182 Gene3D G3DSA:3.10.129.10 31 172 2.6E-44 T 12-10-2018 UA74_05720 1cf9dd572458f2eebcc54ca22fc9cd66 182 SUPERFAMILY SSF54637 40 169 2.19E-34 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_05720 1cf9dd572458f2eebcc54ca22fc9cd66 182 Pfam PF07977 FabA-like domain 46 165 3.2E-21 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 UA74_17435 ec169935a7557319d19cf5009d348638 358 Gene3D G3DSA:1.10.10.10 35 102 4.0E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17435 ec169935a7557319d19cf5009d348638 358 SUPERFAMILY SSF46894 300 358 2.01E-10 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UA74_17435 ec169935a7557319d19cf5009d348638 358 SMART SM00421 294 352 3.4E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17435 ec169935a7557319d19cf5009d348638 358 Gene3D G3DSA:1.10.10.10 296 358 9.2E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17435 ec169935a7557319d19cf5009d348638 358 Pfam PF00196 Bacterial regulatory proteins, luxR family 300 348 4.1E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UA74_17435 ec169935a7557319d19cf5009d348638 358 SUPERFAMILY SSF46785 41 96 3.73E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_15595 c9e645a6bdfc6a91bc7dc466145bea9c 353 Gene3D G3DSA:2.130.10.10 201 352 2.2E-10 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_15595 c9e645a6bdfc6a91bc7dc466145bea9c 353 SUPERFAMILY SSF101898 77 352 2.56E-15 T 12-10-2018 UA74_14160 b4ae87b929966fd6a45fbfdbcf800441 180 SUPERFAMILY SSF46785 2 95 1.03E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14160 b4ae87b929966fd6a45fbfdbcf800441 180 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 45 4.6E-5 T 12-10-2018 UA74_14160 b4ae87b929966fd6a45fbfdbcf800441 180 Gene3D G3DSA:1.10.10.10 1 71 1.1E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_07950 071c54adf9827ecf454f3ee887a0e371 209 SUPERFAMILY SSF52833 11 169 2.49E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily UA74_07950 071c54adf9827ecf454f3ee887a0e371 209 Gene3D G3DSA:3.40.30.10 5 209 1.2E-73 T 12-10-2018 UA74_07950 071c54adf9827ecf454f3ee887a0e371 209 Pfam PF01323 DSBA-like thioredoxin domain 13 167 2.2E-7 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 UA74_13420 05018d119404b09180e447f7ebd08263 297 Pfam PF00753 Metallo-beta-lactamase superfamily 34 228 6.7E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_13420 05018d119404b09180e447f7ebd08263 297 SMART SM00849 35 228 1.1E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_13420 05018d119404b09180e447f7ebd08263 297 SUPERFAMILY SSF56281 12 269 6.3E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_13420 05018d119404b09180e447f7ebd08263 297 Gene3D G3DSA:3.60.15.10 10 251 5.4E-39 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_12735 c66ff7b75d66886bae86813b8cde726e 301 PIRSF PIRSF005355 8 301 2.0E-36 T 12-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 UA74_12735 c66ff7b75d66886bae86813b8cde726e 301 Pfam PF01040 UbiA prenyltransferase family 40 270 1.3E-16 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 UA74_10040 a3f91b908e098a16b16809e39d6e17c4 270 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 258 32.419 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 UA74_10040 a3f91b908e098a16b16809e39d6e17c4 270 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 256 8.6E-77 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 UA74_10040 a3f91b908e098a16b16809e39d6e17c4 270 Gene3D G3DSA:3.20.20.70 1 270 1.4E-106 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_10040 a3f91b908e098a16b16809e39d6e17c4 270 SUPERFAMILY SSF51366 13 258 5.49E-76 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UA74_10040 a3f91b908e098a16b16809e39d6e17c4 270 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 52 69 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 UA74_27810 8c536dcb2aece5651bea3ca7919c8c51 455 SUPERFAMILY SSF55874 331 450 1.26E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_27810 8c536dcb2aece5651bea3ca7919c8c51 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 451 3.9E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_27810 8c536dcb2aece5651bea3ca7919c8c51 455 Gene3D G3DSA:3.30.565.10 323 454 3.7E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_27810 8c536dcb2aece5651bea3ca7919c8c51 455 Pfam PF04024 PspC domain 39 93 2.4E-14 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal UA74_24610 559fefa87600de5fa6d0d91fc9707bda 365 Gene3D G3DSA:3.20.20.70 21 364 5.4E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_24610 559fefa87600de5fa6d0d91fc9707bda 365 SUPERFAMILY SSF51412 27 355 1.68E-48 T 12-10-2018 UA74_24610 559fefa87600de5fa6d0d91fc9707bda 365 Pfam PF03060 Nitronate monooxygenase 31 355 1.1E-75 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 UA74_01950 59c0484659de385b5105ba5bdf89a15e 228 SUPERFAMILY SSF50494 95 219 2.02E-10 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_01950 59c0484659de385b5105ba5bdf89a15e 228 Gene3D G3DSA:2.40.10.10 57 224 1.4E-40 T 12-10-2018 UA74_01950 59c0484659de385b5105ba5bdf89a15e 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 147 164 1.8E-20 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01950 59c0484659de385b5105ba5bdf89a15e 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 191 205 1.8E-20 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01950 59c0484659de385b5105ba5bdf89a15e 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 126 146 1.8E-20 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01950 59c0484659de385b5105ba5bdf89a15e 228 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 166 189 1.8E-20 T 12-10-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 UA74_01950 59c0484659de385b5105ba5bdf89a15e 228 Gene3D G3DSA:2.40.10.10 114 213 1.4E-40 T 12-10-2018 UA74_22610 f30b5800e8cb5f694a86e13dc59b7134 309 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 139 275 1.1E-8 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase UA74_22610 f30b5800e8cb5f694a86e13dc59b7134 309 SUPERFAMILY SSF56219 3 282 1.11E-17 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_02740 68970003ea877a212a25b1ff287d6eea 361 SUPERFAMILY SSF101478 23 350 6.93E-41 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily UA74_02740 68970003ea877a212a25b1ff287d6eea 361 Gene3D G3DSA:1.10.4080.10 26 361 3.2E-53 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily UA74_02740 68970003ea877a212a25b1ff287d6eea 361 Pfam PF03747 ADP-ribosylglycohydrolase 30 337 3.7E-48 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 UA74_01275 03279be5d168d70f71c524fe2eba93f9 394 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 4.6E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_01275 03279be5d168d70f71c524fe2eba93f9 394 PRINTS PR00834 HtrA/DegQ protease family signature 225 237 4.6E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_01275 03279be5d168d70f71c524fe2eba93f9 394 PRINTS PR00834 HtrA/DegQ protease family signature 284 308 4.6E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_01275 03279be5d168d70f71c524fe2eba93f9 394 PRINTS PR00834 HtrA/DegQ protease family signature 324 341 4.6E-7 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UA74_01275 03279be5d168d70f71c524fe2eba93f9 394 Pfam PF13365 Trypsin-like peptidase domain 217 353 1.4E-21 T 12-10-2018 UA74_01275 03279be5d168d70f71c524fe2eba93f9 394 Pfam PF02674 Colicin V production protein 4 146 2.9E-15 T 12-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 UA74_01275 03279be5d168d70f71c524fe2eba93f9 394 Gene3D G3DSA:2.40.10.10 184 270 7.9E-23 T 12-10-2018 UA74_01275 03279be5d168d70f71c524fe2eba93f9 394 SUPERFAMILY SSF50494 191 372 2.07E-33 T 12-10-2018 IPR009003 Peptidase S1, PA clan UA74_01275 03279be5d168d70f71c524fe2eba93f9 394 Gene3D G3DSA:2.40.10.10 277 379 5.1E-18 T 12-10-2018 UA74_26495 639c635354a01fec28a2322203292f09 505 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 289 7.9E-75 T 12-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 UA74_26495 639c635354a01fec28a2322203292f09 505 SUPERFAMILY SSF52777 53 164 1.56E-6 T 12-10-2018 UA74_26495 639c635354a01fec28a2322203292f09 505 Pfam PF06974 Protein of unknown function (DUF1298) 356 501 2.9E-25 T 12-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 UA74_26495 639c635354a01fec28a2322203292f09 505 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 5 503 2.5E-133 T 12-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 UA74_07335 7f90c77a3802edfe24f0107e6fe492a7 550 SUPERFAMILY SSF53850 33 547 2.64E-54 T 12-10-2018 UA74_07335 7f90c77a3802edfe24f0107e6fe492a7 550 Gene3D G3DSA:3.40.190.10 93 519 5.6E-32 T 12-10-2018 UA74_07335 7f90c77a3802edfe24f0107e6fe492a7 550 Pfam PF01547 Bacterial extracellular solute-binding protein 126 366 1.5E-15 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_00285 a7548df9c8977cf38fbd35599cfb686c 320 Gene3D G3DSA:3.20.20.100 1 318 1.8E-106 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_00285 a7548df9c8977cf38fbd35599cfb686c 320 Pfam PF00248 Aldo/keto reductase family 16 314 1.1E-64 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_00285 a7548df9c8977cf38fbd35599cfb686c 320 SUPERFAMILY SSF51430 2 316 7.6E-89 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_02785 1e7947e0d2c380a7930338cfd514f8e6 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 24.943 T 12-10-2018 IPR007551 Protein of unknown function DUF520 UA74_02785 1e7947e0d2c380a7930338cfd514f8e6 163 Gene3D G3DSA:3.30.70.860 5 163 5.7E-60 T 12-10-2018 IPR035571 UPF0234-like, C-terminal UA74_02785 1e7947e0d2c380a7930338cfd514f8e6 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 2.5E-60 T 12-10-2018 IPR007551 Protein of unknown function DUF520 UA74_02785 1e7947e0d2c380a7930338cfd514f8e6 163 SUPERFAMILY SSF89963 5 87 3.66E-26 T 12-10-2018 IPR036183 YajQ-like superfamily UA74_02785 1e7947e0d2c380a7930338cfd514f8e6 163 SUPERFAMILY SSF89963 92 163 1.18E-23 T 12-10-2018 IPR036183 YajQ-like superfamily UA74_02785 1e7947e0d2c380a7930338cfd514f8e6 163 Gene3D G3DSA:3.30.70.990 11 100 5.7E-60 T 12-10-2018 IPR035570 UPF0234, N-terminal UA74_21685 42cf46d2b74aab9e858683aea15efeb3 235 Pfam PF00588 SpoU rRNA Methylase family 83 227 2.5E-34 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UA74_21685 42cf46d2b74aab9e858683aea15efeb3 235 SUPERFAMILY SSF75217 60 234 7.85E-39 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases UA74_21685 42cf46d2b74aab9e858683aea15efeb3 235 SUPERFAMILY SSF55315 3 68 3.3E-6 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like UA74_21685 42cf46d2b74aab9e858683aea15efeb3 235 Gene3D G3DSA:3.40.1280.10 73 235 3.3E-49 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UA74_21685 42cf46d2b74aab9e858683aea15efeb3 235 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 1 66 3.0E-5 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UA74_27470 be184f3998748ddb25baaa5d5ff6cade 137 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 62 102 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UA74_27470 be184f3998748ddb25baaa5d5ff6cade 137 SUPERFAMILY SSF53927 11 134 7.74E-37 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UA74_27470 be184f3998748ddb25baaa5d5ff6cade 137 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 17 107 2.5E-9 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain UA74_27470 be184f3998748ddb25baaa5d5ff6cade 137 Gene3D G3DSA:3.40.140.10 4 136 3.6E-44 T 12-10-2018 UA74_15830 ef0e67b0126185b3b61c379d69dc263a 326 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 10 320 1.4E-72 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_15830 ef0e67b0126185b3b61c379d69dc263a 326 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 5 311 22.167 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_15830 ef0e67b0126185b3b61c379d69dc263a 326 Gene3D G3DSA:3.100.10.20 2 84 1.9E-20 T 12-10-2018 UA74_15830 ef0e67b0126185b3b61c379d69dc263a 326 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 6 326 9.1E-97 T 12-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 UA74_15830 ef0e67b0126185b3b61c379d69dc263a 326 Pfam PF01867 CRISPR associated protein Cas1 10 278 3.0E-67 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 UA74_15830 ef0e67b0126185b3b61c379d69dc263a 326 Gene3D G3DSA:1.20.120.920 86 326 1.4E-55 T 12-10-2018 UA74_22020 9b44eb72376d633479803b65dadb3034 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 7.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22020 9b44eb72376d633479803b65dadb3034 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 7.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22020 9b44eb72376d633479803b65dadb3034 208 Gene3D G3DSA:1.10.357.10 10 199 7.8E-54 T 12-10-2018 UA74_22020 9b44eb72376d633479803b65dadb3034 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 1.1E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_22020 9b44eb72376d633479803b65dadb3034 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UA74_22020 9b44eb72376d633479803b65dadb3034 208 SUPERFAMILY SSF46689 8 90 3.64E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_05505 bf5b72398a18b56bef0faab5ac4c3cf9 196 Pfam PF13302 Acetyltransferase (GNAT) domain 19 156 2.2E-17 T 12-10-2018 IPR000182 GNAT domain UA74_05505 bf5b72398a18b56bef0faab5ac4c3cf9 196 SUPERFAMILY SSF55729 18 180 1.98E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_05505 bf5b72398a18b56bef0faab5ac4c3cf9 196 Gene3D G3DSA:3.40.630.30 16 181 2.9E-32 T 12-10-2018 UA74_14115 37f93e3b5bf97c058ad72d31eee6c75e 301 PIRSF PIRSF028754 4 296 2.6E-104 T 12-10-2018 IPR008492 Protein of unknown function DUF774 UA74_14115 37f93e3b5bf97c058ad72d31eee6c75e 301 Gene3D G3DSA:3.40.50.10900 21 225 2.5E-89 T 12-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily UA74_14115 37f93e3b5bf97c058ad72d31eee6c75e 301 Gene3D G3DSA:1.10.287.100 226 264 2.5E-89 T 12-10-2018 UA74_14115 37f93e3b5bf97c058ad72d31eee6c75e 301 Pfam PF09754 PAC2 family 27 245 4.0E-48 T 12-10-2018 IPR019151 Proteasome assembly chaperone 2 UA74_14115 37f93e3b5bf97c058ad72d31eee6c75e 301 SUPERFAMILY SSF159659 14 267 2.35E-86 T 12-10-2018 UA74_20765 dc284d12ec3a35312d2b2bc0a7af385c 141 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 7 139 1.6E-25 T 12-10-2018 IPR011747 Conserved hypothetical protein CHP02241 UA74_20765 dc284d12ec3a35312d2b2bc0a7af385c 141 Pfam PF06841 T4-like virus tail tube protein gp19 9 138 1.6E-30 T 12-10-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 UA74_08745 32906828b748e19b615631e993281569 243 Pfam PF12079 Protein of unknown function (DUF3558) 48 236 4.6E-8 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_10250 31117d1ce4cefca5db0692c6a3e0fab2 715 Pfam PF10592 AIPR protein 252 535 1.2E-38 T 12-10-2018 IPR018891 Abortive bacteriophage infection, resistance UA74_08580 01004302377d00c46dd98e75c1d39ff4 297 Gene3D G3DSA:3.40.190.10 59 279 1.3E-62 T 12-10-2018 UA74_08580 01004302377d00c46dd98e75c1d39ff4 297 Gene3D G3DSA:3.40.190.10 147 247 1.3E-62 T 12-10-2018 UA74_08580 01004302377d00c46dd98e75c1d39ff4 297 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 59 279 3.5E-48 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_08580 01004302377d00c46dd98e75c1d39ff4 297 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 82 95 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site UA74_08580 01004302377d00c46dd98e75c1d39ff4 297 SUPERFAMILY SSF53850 1 279 7.69E-53 T 12-10-2018 UA74_08580 01004302377d00c46dd98e75c1d39ff4 297 SMART SM00062 58 285 2.2E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_27745 09b1156ae5a1184ac039b2651618e0c9 206 Pfam PF13707 RloB-like protein 25 194 3.9E-26 T 12-10-2018 IPR025591 RloB-like protein UA74_27745 09b1156ae5a1184ac039b2651618e0c9 206 SUPERFAMILY SSF48256 88 178 5.76E-5 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 UA74_21525 9d79b24edc7f121f0612acfba7a533d4 569 SUPERFAMILY SSF52540 8 276 2.62E-117 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_21525 9d79b24edc7f121f0612acfba7a533d4 569 Pfam PF06418 CTP synthase N-terminus 8 276 4.3E-121 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 UA74_21525 9d79b24edc7f121f0612acfba7a533d4 569 Pfam PF00117 Glutamine amidotransferase class-I 311 542 1.1E-47 T 12-10-2018 IPR017926 Glutamine amidotransferase UA74_21525 9d79b24edc7f121f0612acfba7a533d4 569 TIGRFAM TIGR00337 PyrG: CTP synthase 6 543 1.3E-225 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 UA74_21525 9d79b24edc7f121f0612acfba7a533d4 569 Hamap MF_01227 CTP synthase [pyrG]. 7 548 49.926 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 UA74_21525 9d79b24edc7f121f0612acfba7a533d4 569 Gene3D G3DSA:3.40.50.880 296 551 1.2E-98 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_21525 9d79b24edc7f121f0612acfba7a533d4 569 SUPERFAMILY SSF52317 299 549 6.48E-74 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_21525 9d79b24edc7f121f0612acfba7a533d4 569 Gene3D G3DSA:3.40.50.300 2 295 3.3E-131 T 12-10-2018 UA74_17860 610ef07c8a5504f957719eb51722f572 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 295 1.9E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_17860 610ef07c8a5504f957719eb51722f572 306 SUPERFAMILY SSF161098 66 291 7.33E-55 T 12-10-2018 IPR035906 MetI-like superfamily UA74_17860 610ef07c8a5504f957719eb51722f572 306 Gene3D G3DSA:1.10.3720.10 62 303 2.7E-62 T 12-10-2018 IPR035906 MetI-like superfamily UA74_14175 8157d694a315c0e47051f98e4a46738e 518 SUPERFAMILY SSF103473 7 496 1.29E-54 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_14175 8157d694a315c0e47051f98e4a46738e 518 Gene3D G3DSA:1.20.1720.10 16 224 3.9E-38 T 12-10-2018 UA74_14175 8157d694a315c0e47051f98e4a46738e 518 Pfam PF07690 Major Facilitator Superfamily 23 409 4.9E-39 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_14175 8157d694a315c0e47051f98e4a46738e 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 1.3E-6 T 12-10-2018 UA74_14175 8157d694a315c0e47051f98e4a46738e 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 78 100 1.3E-6 T 12-10-2018 UA74_14175 8157d694a315c0e47051f98e4a46738e 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 356 376 1.3E-6 T 12-10-2018 UA74_14175 8157d694a315c0e47051f98e4a46738e 518 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 1.3E-6 T 12-10-2018 UA74_04565 c1e51f455cc90bf9e15180738bda86a6 380 Gene3D G3DSA:3.40.50.2000 3 374 1.3E-78 T 12-10-2018 UA74_04565 c1e51f455cc90bf9e15180738bda86a6 380 Pfam PF13439 Glycosyltransferase Family 4 10 171 3.2E-31 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_04565 c1e51f455cc90bf9e15180738bda86a6 380 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 1 376 3.0E-177 T 12-10-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 KEGG: 00500+2.4.1.342|MetaCyc: PWY-7900 UA74_04565 c1e51f455cc90bf9e15180738bda86a6 380 Gene3D G3DSA:3.40.50.2000 168 357 1.3E-78 T 12-10-2018 UA74_04565 c1e51f455cc90bf9e15180738bda86a6 380 Pfam PF00534 Glycosyl transferases group 1 186 356 6.1E-31 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_04565 c1e51f455cc90bf9e15180738bda86a6 380 SUPERFAMILY SSF53756 5 378 1.15E-84 T 12-10-2018 UA74_00305 83d0e1bdbb997144b9845e2563f4aa4b 433 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 149 307 2.2E-15 T 12-10-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain UA74_05335 988bbef928a71b3a4f318850e61b68a6 178 Gene3D G3DSA:2.30.110.10 37 170 5.0E-13 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_05335 988bbef928a71b3a4f318850e61b68a6 178 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 49 117 6.5E-5 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_05335 988bbef928a71b3a4f318850e61b68a6 178 SUPERFAMILY SSF50475 39 161 6.24E-14 T 12-10-2018 UA74_20645 32afc3662685d8939940e757762c2178 240 Pfam PF02754 Cysteine-rich domain 3 83 8.1E-15 T 12-10-2018 IPR004017 Cysteine-rich domain UA74_20645 32afc3662685d8939940e757762c2178 240 Pfam PF02754 Cysteine-rich domain 124 208 1.9E-15 T 12-10-2018 IPR004017 Cysteine-rich domain UA74_12255 b69fb137d45c0dd98edf72b41a3fa5c8 65 Gene3D G3DSA:3.30.70.20 1 64 8.5E-21 T 12-10-2018 UA74_12255 b69fb137d45c0dd98edf72b41a3fa5c8 65 SUPERFAMILY SSF54862 3 62 2.89E-16 T 12-10-2018 UA74_12255 b69fb137d45c0dd98edf72b41a3fa5c8 65 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 1.6E-14 T 12-10-2018 UA74_12255 b69fb137d45c0dd98edf72b41a3fa5c8 65 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 1.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_12255 b69fb137d45c0dd98edf72b41a3fa5c8 65 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 1.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_12255 b69fb137d45c0dd98edf72b41a3fa5c8 65 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 1.1E-8 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_06140 07042834121f8ec7926c8e379acf0de9 123 Pfam PF04672 S-adenosyl methyltransferase 1 122 2.3E-33 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_06140 07042834121f8ec7926c8e379acf0de9 123 SUPERFAMILY SSF53335 2 103 2.9E-15 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_06140 07042834121f8ec7926c8e379acf0de9 123 Gene3D G3DSA:3.40.50.150 1 123 8.5E-41 T 12-10-2018 UA74_23455 e14fd1e875eb456000fa8c33d8545820 281 SUPERFAMILY SSF46785 49 159 7.1E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_23455 e14fd1e875eb456000fa8c33d8545820 281 Gene3D G3DSA:1.10.10.10 24 156 1.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_23455 e14fd1e875eb456000fa8c33d8545820 281 ProSitePatterns PS01117 MarR-type HTH domain signature. 82 116 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UA74_23455 e14fd1e875eb456000fa8c33d8545820 281 SMART SM00347 43 143 2.3E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_23455 e14fd1e875eb456000fa8c33d8545820 281 Pfam PF01047 MarR family 51 108 2.6E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28090 522cf5a5abcfed784eaa2f05b8e3fa85 537 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 6 494 1.4E-88 T 12-10-2018 IPR007795 Type VII secretion system EccB UA74_28090 522cf5a5abcfed784eaa2f05b8e3fa85 537 Gene3D G3DSA:2.40.50.900 72 154 2.4E-12 T 12-10-2018 UA74_28090 522cf5a5abcfed784eaa2f05b8e3fa85 537 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 4 507 5.5E-113 T 12-10-2018 IPR007795 Type VII secretion system EccB UA74_28090 522cf5a5abcfed784eaa2f05b8e3fa85 537 Gene3D G3DSA:2.40.50.910 269 354 1.7E-10 T 12-10-2018 UA74_00395 940d3cb534b270eef803d86ba4a2bfd3 107 SMART SM00450 1 95 6.5E-24 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_00395 940d3cb534b270eef803d86ba4a2bfd3 107 Gene3D G3DSA:3.40.250.10 6 100 3.0E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_00395 940d3cb534b270eef803d86ba4a2bfd3 107 Pfam PF00581 Rhodanese-like domain 11 91 3.0E-15 T 12-10-2018 IPR001763 Rhodanese-like domain UA74_00395 940d3cb534b270eef803d86ba4a2bfd3 107 SUPERFAMILY SSF52821 10 98 6.02E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily UA74_29205 86df1aa0cc155e7ef9f161613da07cc3 274 Pfam PF14011 EspG family 25 264 7.0E-49 T 12-10-2018 IPR025734 EspG family UA74_08175 d2c214e70e2bef5196678ef971e5f3ce 321 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 1 128 3.0E-28 T 12-10-2018 IPR018768 Domain of unknown function DUF2344 UA74_08175 d2c214e70e2bef5196678ef971e5f3ce 321 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 1 139 2.4E-33 T 12-10-2018 IPR018768 Domain of unknown function DUF2344 UA74_12475 6a1a6e09013db153540bc67151f4168a 544 Pfam PF05960 Bacterial protein of unknown function (DUF885) 25 538 1.7E-106 T 12-10-2018 IPR010281 Protein of unknown function DUF885 UA74_17050 cec2e5558cbb848a0613a05d68027484 653 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 43 556 5.8E-126 T 12-10-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 UA74_17050 cec2e5558cbb848a0613a05d68027484 653 SUPERFAMILY SSF48208 151 372 2.84E-24 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_15815 e0253b8b18633c15b38a3271b3271e5f 224 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 6 135 6.9E-12 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 UA74_15815 e0253b8b18633c15b38a3271b3271e5f 224 Gene3D G3DSA:3.30.70.2660 4 133 2.0E-7 T 12-10-2018 UA74_15815 e0253b8b18633c15b38a3271b3271e5f 224 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 5 46 1.4E-8 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal UA74_14495 32b664dee68b7fdf35c83b3b7daccb34 395 Gene3D G3DSA:3.20.20.30 1 343 1.2E-62 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_14495 32b664dee68b7fdf35c83b3b7daccb34 395 Pfam PF00296 Luciferase-like monooxygenase 1 264 6.4E-51 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_14495 32b664dee68b7fdf35c83b3b7daccb34 395 SUPERFAMILY SSF51679 1 332 1.13E-63 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_14495 32b664dee68b7fdf35c83b3b7daccb34 395 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 353 2.5E-185 T 12-10-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative UA74_13065 3ae18e363fdac874c6287af1c82dac68 287 Pfam PF12822 ECF transporter, substrate-specific component 91 259 3.4E-16 T 12-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 UA74_13065 3ae18e363fdac874c6287af1c82dac68 287 Gene3D G3DSA:1.10.1760.20 81 279 1.7E-8 T 12-10-2018 UA74_13065 3ae18e363fdac874c6287af1c82dac68 287 PIRSF PIRSF037395 20 281 8.8E-92 T 12-10-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 UA74_28870 b7f9294eb6f173d3865a2e3aa496a607 320 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 82 225 8.2E-45 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_28870 b7f9294eb6f173d3865a2e3aa496a607 320 Gene3D G3DSA:1.10.260.150 44 315 6.0E-70 T 12-10-2018 UA74_28870 b7f9294eb6f173d3865a2e3aa496a607 320 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 82 225 6.1E-41 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_14670 b618265b9c01c29a4cca0df3f4eef96d 205 Pfam PF00072 Response regulator receiver domain 25 81 6.0E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UA74_14670 b618265b9c01c29a4cca0df3f4eef96d 205 Gene3D G3DSA:3.40.50.12740 20 176 2.2E-7 T 12-10-2018 UA74_14670 b618265b9c01c29a4cca0df3f4eef96d 205 SUPERFAMILY SSF52172 26 84 1.25E-8 T 12-10-2018 IPR011006 CheY-like superfamily UA74_08620 fb19c4b279cb241b4b4ffc9e741e0822 425 SUPERFAMILY SSF103473 2 391 1.83E-37 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_08620 fb19c4b279cb241b4b4ffc9e741e0822 425 Pfam PF05977 Transmembrane secretion effector 1 392 2.9E-22 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_08620 fb19c4b279cb241b4b4ffc9e741e0822 425 Gene3D G3DSA:1.20.1250.20 1 385 1.8E-32 T 12-10-2018 UA74_27880 9a09ee20b61e444c92da8767a40a7206 132 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 9 122 1.0E-27 T 12-10-2018 IPR035165 Protein of unknown function DUF5319 UA74_27880 9a09ee20b61e444c92da8767a40a7206 132 Pfam PF17252 Family of unknown function (DUF5319) 6 124 1.7E-48 T 12-10-2018 IPR035165 Protein of unknown function DUF5319 UA74_06415 fd457f984ee0ee30e31b451bf4174f1c 306 SUPERFAMILY SSF51735 32 246 3.15E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_06415 fd457f984ee0ee30e31b451bf4174f1c 306 Gene3D G3DSA:3.40.50.720 27 306 5.7E-36 T 12-10-2018 UA74_06415 fd457f984ee0ee30e31b451bf4174f1c 306 Pfam PF00106 short chain dehydrogenase 33 171 5.9E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_05450 dd87d1752a84d0fc3e43d76dc3faa996 252 SUPERFAMILY SSF46689 34 96 5.49E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_05450 dd87d1752a84d0fc3e43d76dc3faa996 252 Gene3D G3DSA:1.10.10.60 30 81 4.7E-15 T 12-10-2018 UA74_05450 dd87d1752a84d0fc3e43d76dc3faa996 252 SUPERFAMILY SSF48498 108 214 1.11E-18 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_05450 dd87d1752a84d0fc3e43d76dc3faa996 252 Pfam PF00440 Bacterial regulatory proteins, tetR family 46 90 2.8E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05450 dd87d1752a84d0fc3e43d76dc3faa996 252 Pfam PF16859 Bacterial transcriptional repressor C-terminal 100 209 1.7E-23 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UA74_05450 dd87d1752a84d0fc3e43d76dc3faa996 252 Gene3D G3DSA:1.10.357.10 83 220 1.6E-25 T 12-10-2018 UA74_05450 dd87d1752a84d0fc3e43d76dc3faa996 252 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 57 3.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05450 dd87d1752a84d0fc3e43d76dc3faa996 252 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 3.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03340 3f2a171ddc45acf3f5f271bd68dcf63a 342 Gene3D G3DSA:1.10.10.10 3 75 5.7E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_03340 3f2a171ddc45acf3f5f271bd68dcf63a 342 Pfam PF13280 WYL domain 151 321 1.3E-34 T 12-10-2018 IPR026881 WYL domain UA74_03340 3f2a171ddc45acf3f5f271bd68dcf63a 342 Pfam PF08279 HTH domain 17 72 8.9E-12 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 UA74_03340 3f2a171ddc45acf3f5f271bd68dcf63a 342 SUPERFAMILY SSF46785 15 72 2.17E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_03340 3f2a171ddc45acf3f5f271bd68dcf63a 342 PIRSF PIRSF016838 9 66 1.0E-4 T 12-10-2018 IPR028349 Protein PafC UA74_03340 3f2a171ddc45acf3f5f271bd68dcf63a 342 PIRSF PIRSF016838 75 325 1.1E-26 T 12-10-2018 IPR028349 Protein PafC UA74_19100 faf07751241f7cff5229a3a075e6dd8e 2235 SMART SM00490 1038 1123 5.0E-14 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_19100 faf07751241f7cff5229a3a075e6dd8e 2235 Pfam PF00271 Helicase conserved C-terminal domain 1049 1121 2.8E-9 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_19100 faf07751241f7cff5229a3a075e6dd8e 2235 Pfam PF00270 DEAD/DEAH box helicase 80 272 3.2E-16 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UA74_19100 faf07751241f7cff5229a3a075e6dd8e 2235 Gene3D G3DSA:3.40.50.300 1028 1146 1.4E-16 T 12-10-2018 UA74_19100 faf07751241f7cff5229a3a075e6dd8e 2235 SUPERFAMILY SSF52540 98 1149 5.63E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19100 faf07751241f7cff5229a3a075e6dd8e 2235 SMART SM00487 73 315 7.5E-15 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UA74_19100 faf07751241f7cff5229a3a075e6dd8e 2235 SUPERFAMILY SSF52540 65 284 2.94E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_19100 faf07751241f7cff5229a3a075e6dd8e 2235 Pfam PF09369 Domain of unknown function (DUF1998) 1624 1711 4.8E-8 T 12-10-2018 IPR018973 DEAD/DEAH-box helicase, putative UA74_19100 faf07751241f7cff5229a3a075e6dd8e 2235 Gene3D G3DSA:3.40.50.300 64 290 3.6E-35 T 12-10-2018 UA74_11060 98b6a2cf1e94610fb5003f19fa3212d3 387 SUPERFAMILY SSF51905 2 362 1.65E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_11060 98b6a2cf1e94610fb5003f19fa3212d3 387 Pfam PF01494 FAD binding domain 1 335 3.0E-28 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 UA74_11060 98b6a2cf1e94610fb5003f19fa3212d3 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 137 152 3.3E-13 T 12-10-2018 UA74_11060 98b6a2cf1e94610fb5003f19fa3212d3 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 288 3.3E-13 T 12-10-2018 UA74_11060 98b6a2cf1e94610fb5003f19fa3212d3 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 304 3.3E-13 T 12-10-2018 UA74_11060 98b6a2cf1e94610fb5003f19fa3212d3 387 Gene3D G3DSA:3.50.50.60 1 347 1.1E-82 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_13580 594be087fb23053d34d9575e8c5d369a 192 Pfam PF03079 ARD/ARD' family 15 169 4.9E-29 T 12-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 UA74_13580 594be087fb23053d34d9575e8c5d369a 192 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 177 34.599 T 12-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 UA74_13580 594be087fb23053d34d9575e8c5d369a 192 Gene3D G3DSA:2.60.120.10 2 162 3.7E-45 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_13580 594be087fb23053d34d9575e8c5d369a 192 SUPERFAMILY SSF51182 5 183 1.71E-30 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_21895 34741835ce1270c25efa7d80b507bdb0 326 SUPERFAMILY SSF51679 1 322 2.06E-61 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_21895 34741835ce1270c25efa7d80b507bdb0 326 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 322 1.9E-139 T 12-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related UA74_21895 34741835ce1270c25efa7d80b507bdb0 326 Gene3D G3DSA:3.20.20.30 2 323 8.1E-63 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_21895 34741835ce1270c25efa7d80b507bdb0 326 Pfam PF00296 Luciferase-like monooxygenase 3 294 3.9E-50 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_02115 f709905b42318aa9060cd2639b3acaf6 258 Pfam PF00483 Nucleotidyl transferase 8 246 1.9E-14 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UA74_02115 f709905b42318aa9060cd2639b3acaf6 258 Gene3D G3DSA:3.90.550.10 5 257 2.2E-40 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_02115 f709905b42318aa9060cd2639b3acaf6 258 SUPERFAMILY SSF53448 5 249 7.43E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_30235 0661d79d27684e028930730be6e36c1b 538 SUPERFAMILY SSF56112 33 254 6.83E-11 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_30235 0661d79d27684e028930730be6e36c1b 538 Gene3D G3DSA:1.10.510.10 130 286 1.0E-37 T 12-10-2018 UA74_30235 0661d79d27684e028930730be6e36c1b 538 Gene3D G3DSA:3.30.200.20 25 129 1.2E-21 T 12-10-2018 UA74_03990 77ebfdf851f155f1bfbb78b4c8524c2d 99 Gene3D G3DSA:1.10.287.1060 1 96 1.1E-6 T 12-10-2018 UA74_09660 b49e3365665bea81cdc7d9963adef5d5 338 SUPERFAMILY SSF51679 1 330 4.45E-75 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_09660 b49e3365665bea81cdc7d9963adef5d5 338 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 2 330 6.3E-140 T 12-10-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase UA74_09660 b49e3365665bea81cdc7d9963adef5d5 338 Gene3D G3DSA:3.20.20.30 1 333 1.5E-97 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_09660 b49e3365665bea81cdc7d9963adef5d5 338 Pfam PF00296 Luciferase-like monooxygenase 9 304 1.8E-62 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_09660 b49e3365665bea81cdc7d9963adef5d5 338 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 4 331 3.9E-82 T 12-10-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related UA74_15425 f4b43c5bf1e8337f6a230170e9c3fb40 218 SUPERFAMILY SSF48498 114 217 1.41E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_15425 f4b43c5bf1e8337f6a230170e9c3fb40 218 Gene3D G3DSA:1.10.357.10 30 218 5.0E-47 T 12-10-2018 UA74_15425 f4b43c5bf1e8337f6a230170e9c3fb40 218 SUPERFAMILY SSF46689 35 115 1.45E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_15425 f4b43c5bf1e8337f6a230170e9c3fb40 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 3.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15425 f4b43c5bf1e8337f6a230170e9c3fb40 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 3.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_15425 f4b43c5bf1e8337f6a230170e9c3fb40 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 93 2.2E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_27515 81b7c6d85161e47a1c5c6d2dd104587e 463 Gene3D G3DSA:3.40.710.10 74 376 5.7E-69 T 12-10-2018 UA74_27515 81b7c6d85161e47a1c5c6d2dd104587e 463 SUPERFAMILY SSF56601 98 342 1.11E-46 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_27515 81b7c6d85161e47a1c5c6d2dd104587e 463 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 209 222 2.1E-7 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UA74_27515 81b7c6d85161e47a1c5c6d2dd104587e 463 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 183 200 2.1E-7 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UA74_27515 81b7c6d85161e47a1c5c6d2dd104587e 463 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 146 2.1E-7 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UA74_27515 81b7c6d85161e47a1c5c6d2dd104587e 463 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 99 322 5.7E-28 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 UA74_23475 260b97468e35a3b87ada788c21728cc9 209 Gene3D G3DSA:3.30.530.20 2 146 3.9E-21 T 12-10-2018 IPR023393 START-like domain superfamily UA74_23475 260b97468e35a3b87ada788c21728cc9 209 SUPERFAMILY SSF55961 4 141 3.6E-14 T 12-10-2018 UA74_23475 260b97468e35a3b87ada788c21728cc9 209 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 141 7.8E-9 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase UA74_03090 55c21ad89995b6aaf3e3605acd7d23fb 287 SUPERFAMILY SSF53335 75 266 3.66E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_03090 55c21ad89995b6aaf3e3605acd7d23fb 287 Gene3D G3DSA:3.40.50.150 74 279 9.3E-51 T 12-10-2018 UA74_03090 55c21ad89995b6aaf3e3605acd7d23fb 287 Pfam PF13649 Methyltransferase domain 122 212 2.9E-17 T 12-10-2018 UA74_02805 bd9bde2b3237f8ed432d36a20c3fe2cd 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 2.2E-20 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02805 bd9bde2b3237f8ed432d36a20c3fe2cd 54 SUPERFAMILY SSF57829 4 54 3.6E-18 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 UA74_02805 bd9bde2b3237f8ed432d36a20c3fe2cd 54 Gene3D G3DSA:2.20.28.120 2 54 3.9E-23 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02805 bd9bde2b3237f8ed432d36a20c3fe2cd 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 18.93 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_02805 bd9bde2b3237f8ed432d36a20c3fe2cd 54 Pfam PF00471 Ribosomal protein L33 9 54 2.9E-21 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_14320 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SUPERFAMILY SSF51126 89 408 7.6E-14 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor UA74_14320 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SMART SM00710 158 180 1000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_14320 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SMART SM00710 368 397 1100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_14320 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SMART SM00710 211 233 2600.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_14320 d24863e3cf8741acbdf0bdbecd7d3a0d 408 SMART SM00710 316 338 220.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat UA74_14320 d24863e3cf8741acbdf0bdbecd7d3a0d 408 Gene3D G3DSA:2.160.20.10 87 347 2.5E-10 T 12-10-2018 IPR012334 Pectin lyase fold UA74_23330 f000a5a8ff3a6c027ecd709272cd4133 378 Gene3D G3DSA:3.40.50.150 146 367 4.3E-68 T 12-10-2018 UA74_23330 f000a5a8ff3a6c027ecd709272cd4133 378 SUPERFAMILY SSF53335 149 308 8.68E-15 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_14620 ffb9b8ef2af490b2830c4f626054a2b9 267 SUPERFAMILY SSF56112 16 197 9.48E-23 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_14620 ffb9b8ef2af490b2830c4f626054a2b9 267 Pfam PF01636 Phosphotransferase enzyme family 112 184 4.4E-8 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_14620 ffb9b8ef2af490b2830c4f626054a2b9 267 Gene3D G3DSA:3.90.1200.10 81 192 7.3E-10 T 12-10-2018 UA74_29100 cca7b548ee063fb4fe8a5d8af2a574d1 304 SUPERFAMILY SSF161098 35 291 6.17E-38 T 12-10-2018 IPR035906 MetI-like superfamily UA74_29100 cca7b548ee063fb4fe8a5d8af2a574d1 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 299 1.7E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_29100 cca7b548ee063fb4fe8a5d8af2a574d1 304 Gene3D G3DSA:1.10.3720.10 84 303 1.1E-31 T 12-10-2018 IPR035906 MetI-like superfamily UA74_29100 cca7b548ee063fb4fe8a5d8af2a574d1 304 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 31 297 3.3E-78 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 UA74_13060 83f3d1677c9670311c290a3620e232f0 236 Pfam PF05331 Protein of unknown function (DUF742) 126 236 1.6E-28 T 12-10-2018 IPR007995 Protein of unknown function DUF742 UA74_14010 6cb0f07c75fdf20100589b32db211539 192 SUPERFAMILY SSF53927 48 174 5.69E-22 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UA74_14010 6cb0f07c75fdf20100589b32db211539 192 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 47 149 1.7E-14 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain UA74_14010 6cb0f07c75fdf20100589b32db211539 192 Gene3D G3DSA:3.40.140.10 42 184 1.3E-26 T 12-10-2018 UA74_19705 7f64a4dc1ad045f1b495f1a8cef60dfe 371 SUPERFAMILY SSF56601 43 360 2.65E-68 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_19705 7f64a4dc1ad045f1b495f1a8cef60dfe 371 Gene3D G3DSA:3.40.710.10 28 370 9.5E-78 T 12-10-2018 UA74_19705 7f64a4dc1ad045f1b495f1a8cef60dfe 371 Pfam PF00144 Beta-lactamase 49 368 1.2E-50 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_11695 e9b62b466ff12b521fb68f541af7cea5 560 PRINTS PR00868 DNA-polymerase family A (pol I) signature 333 356 5.7E-5 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_11695 e9b62b466ff12b521fb68f541af7cea5 560 PRINTS PR00868 DNA-polymerase family A (pol I) signature 502 515 5.7E-5 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_11695 e9b62b466ff12b521fb68f541af7cea5 560 PRINTS PR00868 DNA-polymerase family A (pol I) signature 473 489 5.7E-5 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_11695 e9b62b466ff12b521fb68f541af7cea5 560 Gene3D G3DSA:3.30.70.370 304 537 4.2E-27 T 12-10-2018 UA74_11695 e9b62b466ff12b521fb68f541af7cea5 560 SMART SM00482 319 519 1.9E-11 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_11695 e9b62b466ff12b521fb68f541af7cea5 560 Pfam PF00476 DNA polymerase family A 217 537 3.0E-28 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UA74_11695 e9b62b466ff12b521fb68f541af7cea5 560 SUPERFAMILY SSF56672 163 559 1.89E-61 T 12-10-2018 UA74_11695 e9b62b466ff12b521fb68f541af7cea5 560 Gene3D G3DSA:1.10.150.20 342 480 4.2E-27 T 12-10-2018 UA74_25275 da6f56972da539bdc49519c78deebb12 193 SUPERFAMILY SSF143990 29 190 1.14E-43 T 12-10-2018 IPR037238 YbiA-like superfamily UA74_25275 da6f56972da539bdc49519c78deebb12 193 Gene3D G3DSA:1.10.357.40 35 193 1.0E-38 T 12-10-2018 IPR037238 YbiA-like superfamily UA74_25275 da6f56972da539bdc49519c78deebb12 193 Pfam PF08719 Domain of unknown function (DUF1768) 41 188 4.2E-49 T 12-10-2018 IPR012816 NADAR UA74_25275 da6f56972da539bdc49519c78deebb12 193 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 37 188 1.2E-46 T 12-10-2018 IPR012816 NADAR UA74_04055 0152dbf454982b175dd24f79583decee 270 Gene3D G3DSA:3.40.50.150 2 260 2.9E-71 T 12-10-2018 UA74_04055 0152dbf454982b175dd24f79583decee 270 SUPERFAMILY SSF53335 15 223 2.75E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_27710 cad62c5d7dd2a5a56037c4c5210aa575 377 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 168 183 - T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 UA74_27710 cad62c5d7dd2a5a56037c4c5210aa575 377 Gene3D G3DSA:3.40.50.150 14 244 1.0E-53 T 12-10-2018 UA74_27710 cad62c5d7dd2a5a56037c4c5210aa575 377 SUPERFAMILY SSF53335 17 212 1.49E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_27710 cad62c5d7dd2a5a56037c4c5210aa575 377 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 19 212 1.1E-30 T 12-10-2018 UA74_24490 a66f7dc0787fbee23cf3b1b6a0656cfd 198 Pfam PF02130 Uncharacterized protein family UPF0054 22 150 5.0E-36 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 UA74_24490 a66f7dc0787fbee23cf3b1b6a0656cfd 198 Gene3D G3DSA:3.40.390.30 2 155 8.1E-37 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 UA74_24490 a66f7dc0787fbee23cf3b1b6a0656cfd 198 SUPERFAMILY SSF55486 10 153 1.12E-37 T 12-10-2018 UA74_24490 a66f7dc0787fbee23cf3b1b6a0656cfd 198 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 3 179 21.185 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 UA74_24490 a66f7dc0787fbee23cf3b1b6a0656cfd 198 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 151 3.0E-31 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 UA74_24490 a66f7dc0787fbee23cf3b1b6a0656cfd 198 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 121 131 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site UA74_28370 0f4ad6ddb0845ca3c1c8f52d1330e6bd 131 Pfam PF00313 'Cold-shock' DNA-binding domain 7 66 4.8E-16 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_28370 0f4ad6ddb0845ca3c1c8f52d1330e6bd 131 SUPERFAMILY SSF50249 4 71 5.63E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_28370 0f4ad6ddb0845ca3c1c8f52d1330e6bd 131 PRINTS PR00050 Cold shock protein signature 27 36 3.0E-12 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_28370 0f4ad6ddb0845ca3c1c8f52d1330e6bd 131 PRINTS PR00050 Cold shock protein signature 7 22 3.0E-12 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_28370 0f4ad6ddb0845ca3c1c8f52d1330e6bd 131 PRINTS PR00050 Cold shock protein signature 41 59 3.0E-12 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UA74_28370 0f4ad6ddb0845ca3c1c8f52d1330e6bd 131 Gene3D G3DSA:2.40.50.140 6 67 6.2E-20 T 12-10-2018 UA74_28370 0f4ad6ddb0845ca3c1c8f52d1330e6bd 131 SMART SM00357 6 68 2.5E-22 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 UA74_28640 475e13a6ce058ad965962cf8dd258666 170 SUPERFAMILY SSF46785 7 137 2.33E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_28640 475e13a6ce058ad965962cf8dd258666 170 Gene3D G3DSA:1.10.10.10 1 141 1.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_21490 01693be96fe2ea8fdd7a124e9ddcc4f1 198 Pfam PF08044 Domain of unknown function (DUF1707) 10 62 1.9E-20 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 UA74_21490 01693be96fe2ea8fdd7a124e9ddcc4f1 198 Pfam PF05154 TM2 domain 134 182 4.9E-9 T 12-10-2018 IPR007829 TM2 domain UA74_18150 cb9fd2188efba1b05ea72eb57a814cbf 294 SUPERFAMILY SSF161098 55 281 9.94E-58 T 12-10-2018 IPR035906 MetI-like superfamily UA74_18150 cb9fd2188efba1b05ea72eb57a814cbf 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 284 2.1E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_18150 cb9fd2188efba1b05ea72eb57a814cbf 294 Gene3D G3DSA:1.10.3720.10 50 291 2.4E-65 T 12-10-2018 IPR035906 MetI-like superfamily UA74_08135 877a2c55b3c1cfa62d25a5d68e6ae016 162 Pfam PF14017 Protein of unknown function (DUF4233) 48 150 1.2E-22 T 12-10-2018 IPR025327 Protein of unknown function DUF4233 UA74_19935 16e3cc5ae6fe6a9935a477985ff247b6 310 Gene3D G3DSA:1.10.357.10 109 301 1.4E-15 T 12-10-2018 UA74_19935 16e3cc5ae6fe6a9935a477985ff247b6 310 Pfam PF00440 Bacterial regulatory proteins, tetR family 124 166 1.0E-4 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_19935 16e3cc5ae6fe6a9935a477985ff247b6 310 SUPERFAMILY SSF46689 116 172 6.16E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_29725 906186fc37afbee2320a058b21ebdc1e 267 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_29725 906186fc37afbee2320a058b21ebdc1e 267 SUPERFAMILY SSF52540 8 238 3.97E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29725 906186fc37afbee2320a058b21ebdc1e 267 SMART SM00382 39 224 2.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_29725 906186fc37afbee2320a058b21ebdc1e 267 Gene3D G3DSA:3.40.50.300 8 264 1.1E-65 T 12-10-2018 UA74_29725 906186fc37afbee2320a058b21ebdc1e 267 Pfam PF00005 ABC transporter 30 177 3.8E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_23975 c30483ed7f6d5e9b6ab0a63663749736 346 Gene3D G3DSA:3.40.190.10 52 320 6.3E-58 T 12-10-2018 UA74_23975 c30483ed7f6d5e9b6ab0a63663749736 346 Gene3D G3DSA:3.40.190.10 125 226 6.3E-58 T 12-10-2018 UA74_23975 c30483ed7f6d5e9b6ab0a63663749736 346 Pfam PF09084 NMT1/THI5 like 55 263 4.3E-37 T 12-10-2018 IPR015168 SsuA/THI5-like UA74_23975 c30483ed7f6d5e9b6ab0a63663749736 346 SMART SM00062 46 269 0.0098 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UA74_23975 c30483ed7f6d5e9b6ab0a63663749736 346 SUPERFAMILY SSF53850 45 275 2.23E-37 T 12-10-2018 UA74_08370 2c923849be40b4fa48e69b9ac4aa0df4 273 Pfam PF07070 SpoOM protein 2 222 5.4E-53 T 12-10-2018 IPR009776 Sporulation stage 0, protein M UA74_29375 497f64625b913674122122a44ccc52b5 204 Gene3D G3DSA:1.10.10.10 69 204 3.0E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_29375 497f64625b913674122122a44ccc52b5 204 SUPERFAMILY SSF46785 73 203 2.26E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_25075 7e2969e972ce734586b76b94f68ef246 304 SUPERFAMILY SSF51735 9 262 3.33E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_25075 7e2969e972ce734586b76b94f68ef246 304 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 11 297 6.7E-91 T 12-10-2018 IPR010099 Epimerase family protein SDR39U1 UA74_25075 7e2969e972ce734586b76b94f68ef246 304 Gene3D G3DSA:3.40.50.720 4 292 7.3E-71 T 12-10-2018 UA74_25075 7e2969e972ce734586b76b94f68ef246 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 127 2.4E-7 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_25075 7e2969e972ce734586b76b94f68ef246 304 Pfam PF08338 Domain of unknown function (DUF1731) 254 298 4.4E-15 T 12-10-2018 IPR013549 Domain of unknown function DUF1731 UA74_28830 e32818015ce580b5fc224c1b395e417f 283 Gene3D G3DSA:3.90.550.10 1 256 2.7E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_28830 e32818015ce580b5fc224c1b395e417f 283 SUPERFAMILY SSF53448 1 255 1.82E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_29195 1167f096c8c467643e7950cc1bd1c410 232 Pfam PF12079 Protein of unknown function (DUF3558) 50 210 5.0E-14 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_09355 d7d8eaa65bacb0c7ac838e89f43b6347 178 Pfam PF13563 2'-5' RNA ligase superfamily 43 153 6.8E-9 T 12-10-2018 UA74_09355 d7d8eaa65bacb0c7ac838e89f43b6347 178 SUPERFAMILY SSF55144 2 176 5.23E-18 T 12-10-2018 IPR009097 Cyclic phosphodiesterase UA74_09355 d7d8eaa65bacb0c7ac838e89f43b6347 178 Gene3D G3DSA:3.90.1140.10 1 177 3.8E-22 T 12-10-2018 UA74_26945 6f8c7c2ede2b882e351517ab4b60a0db 150 Pfam PF08044 Domain of unknown function (DUF1707) 27 79 7.8E-20 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 UA74_07370 2a196e7ceceb9ff544ffb5ac1d5e532a 315 Gene3D G3DSA:3.30.470.20 204 311 6.7E-17 T 12-10-2018 UA74_07370 2a196e7ceceb9ff544ffb5ac1d5e532a 315 TIGRFAM TIGR04187 GRASP_SAV_5884: ATP-grasp ribosomal peptide maturase, SAV_5884 family 2 310 5.4E-116 T 12-10-2018 IPR026449 ATP-grasp ribosomal peptide maturase, SAV-5884 family UA74_07370 2a196e7ceceb9ff544ffb5ac1d5e532a 315 SUPERFAMILY SSF56059 128 309 3.91E-21 T 12-10-2018 UA74_01850 6d33218b82df153126c1ec91bacb323e 365 Pfam PF03747 ADP-ribosylglycohydrolase 14 329 1.9E-54 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 UA74_01850 6d33218b82df153126c1ec91bacb323e 365 SUPERFAMILY SSF101478 6 348 5.23E-47 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily UA74_01850 6d33218b82df153126c1ec91bacb323e 365 Gene3D G3DSA:1.10.4080.10 9 357 1.7E-54 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily UA74_18110 0a1c221839ff0786982dbbf6ef1375ae 261 Pfam PF12730 ABC-2 family transporter protein 16 194 2.0E-9 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UA74_06930 bb3b40fdedee3b57f229e4bfc7de7646 310 SUPERFAMILY SSF160240 221 297 1.44E-8 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 UA74_06930 bb3b40fdedee3b57f229e4bfc7de7646 310 Gene3D G3DSA:1.20.1510.10 19 217 7.2E-35 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily UA74_06930 bb3b40fdedee3b57f229e4bfc7de7646 310 Pfam PF01545 Cation efflux family 23 217 8.3E-37 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UA74_06930 bb3b40fdedee3b57f229e4bfc7de7646 310 SUPERFAMILY SSF161111 18 218 3.01E-46 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily UA74_06930 bb3b40fdedee3b57f229e4bfc7de7646 310 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 299 6.0E-73 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UA74_21450 fe415f290f48ca89cf58470838d48976 264 SUPERFAMILY SSF55174 24 78 1.24E-13 T 12-10-2018 UA74_21450 fe415f290f48ca89cf58470838d48976 264 Gene3D G3DSA:3.30.70.580 91 248 1.1E-51 T 12-10-2018 UA74_21450 fe415f290f48ca89cf58470838d48976 264 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 126 140 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 UA74_21450 fe415f290f48ca89cf58470838d48976 264 Gene3D G3DSA:3.30.70.1560 150 240 1.1E-51 T 12-10-2018 UA74_21450 fe415f290f48ca89cf58470838d48976 264 SMART SM00363 27 88 2.6E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_21450 fe415f290f48ca89cf58470838d48976 264 SUPERFAMILY SSF55120 79 262 5.58E-45 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_21450 fe415f290f48ca89cf58470838d48976 264 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 93 251 5.0E-45 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 UA74_21450 fe415f290f48ca89cf58470838d48976 264 Pfam PF01479 S4 domain 28 69 2.4E-13 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_21450 fe415f290f48ca89cf58470838d48976 264 Gene3D G3DSA:3.10.290.10 22 85 1.4E-21 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UA74_21450 fe415f290f48ca89cf58470838d48976 264 Pfam PF00849 RNA pseudouridylate synthase 88 220 1.8E-22 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UA74_13250 fad727e7ccac2f8438feec502c1a2560 419 Gene3D G3DSA:1.20.1250.20 11 393 1.3E-31 T 12-10-2018 UA74_13250 fad727e7ccac2f8438feec502c1a2560 419 SUPERFAMILY SSF103473 13 406 8.89E-36 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_13250 fad727e7ccac2f8438feec502c1a2560 419 ProSitePatterns PS00216 Sugar transport proteins signature 1. 67 84 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UA74_13250 fad727e7ccac2f8438feec502c1a2560 419 Pfam PF07690 Major Facilitator Superfamily 20 225 3.0E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_11670 3b995735661c44199c92fd8de40a62d3 384 SMART SM00332 87 373 9.7E-6 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_11670 3b995735661c44199c92fd8de40a62d3 384 Pfam PF13672 Protein phosphatase 2C 108 330 1.5E-13 T 12-10-2018 UA74_11670 3b995735661c44199c92fd8de40a62d3 384 SUPERFAMILY SSF81606 97 375 3.14E-35 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UA74_12140 e8fc4a59f998aef238a802b9dd20201e 369 SUPERFAMILY SSF56796 10 353 1.01E-101 T 12-10-2018 UA74_12140 e8fc4a59f998aef238a802b9dd20201e 369 Gene3D G3DSA:3.40.50.1970 1 171 1.9E-59 T 12-10-2018 UA74_12140 e8fc4a59f998aef238a802b9dd20201e 369 Pfam PF01761 3-dehydroquinate synthase 66 322 2.0E-93 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_12140 e8fc4a59f998aef238a802b9dd20201e 369 Gene3D G3DSA:1.20.1090.10 172 359 5.9E-68 T 12-10-2018 UA74_12140 e8fc4a59f998aef238a802b9dd20201e 369 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 338 3.6E-108 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_12140 e8fc4a59f998aef238a802b9dd20201e 369 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 4 358 62.678 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_12140 e8fc4a59f998aef238a802b9dd20201e 369 PIRSF PIRSF001455 4 351 1.3E-99 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UA74_09695 3c374a94d98b0c07500f381ece9b1162 236 Gene3D G3DSA:3.60.140.10 1 234 2.2E-76 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily UA74_09695 3c374a94d98b0c07500f381ece9b1162 236 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 8 231 3.5E-72 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase UA74_09695 3c374a94d98b0c07500f381ece9b1162 236 SUPERFAMILY SSF64438 3 233 3.3E-72 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic UA74_09695 3c374a94d98b0c07500f381ece9b1162 236 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 13 232 1.1E-52 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase UA74_12880 8e037ff30e0f42bb553e35684c390896 65 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 65 16.883 T 12-10-2018 IPR008515 Ubiquitin-like, Pup UA74_12880 8e037ff30e0f42bb553e35684c390896 65 Pfam PF05639 Pup-like protein 3 65 4.6E-22 T 12-10-2018 IPR008515 Ubiquitin-like, Pup UA74_12880 8e037ff30e0f42bb553e35684c390896 65 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 34 65 1.6E-20 T 12-10-2018 IPR008515 Ubiquitin-like, Pup UA74_11335 998a78768a509dfb66146e3a7d940f33 381 SUPERFAMILY SSF51905 4 378 1.68E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_11335 998a78768a509dfb66146e3a7d940f33 381 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 UA74_11335 998a78768a509dfb66146e3a7d940f33 381 Pfam PF01266 FAD dependent oxidoreductase 5 359 3.3E-53 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_11335 998a78768a509dfb66146e3a7d940f33 381 SUPERFAMILY SSF54373 215 320 7.45E-20 T 12-10-2018 UA74_11335 998a78768a509dfb66146e3a7d940f33 381 Gene3D G3DSA:3.30.9.10 60 320 4.4E-122 T 12-10-2018 UA74_11335 998a78768a509dfb66146e3a7d940f33 381 Gene3D G3DSA:3.50.50.60 5 365 4.4E-122 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_24100 1accd9201b549fd6631929897d0d3fae 438 Pfam PF00144 Beta-lactamase 54 431 4.9E-68 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_24100 1accd9201b549fd6631929897d0d3fae 438 SUPERFAMILY SSF56601 45 433 3.99E-85 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_24100 1accd9201b549fd6631929897d0d3fae 438 Gene3D G3DSA:3.40.710.10 34 438 3.3E-125 T 12-10-2018 UA74_06540 5f9e0e22b33b3edd87be1f6857b1f5c5 69 Pfam PF04149 Domain of unknown function (DUF397) 11 64 2.3E-19 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_04860 c01a31f5b89c126923f550f6647562a4 196 Pfam PF00583 Acetyltransferase (GNAT) family 46 169 8.7E-8 T 12-10-2018 IPR000182 GNAT domain UA74_04860 c01a31f5b89c126923f550f6647562a4 196 SUPERFAMILY SSF55729 13 192 1.92E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_04860 c01a31f5b89c126923f550f6647562a4 196 Gene3D G3DSA:3.40.630.30 11 185 1.1E-19 T 12-10-2018 UA74_05475 4df6288e7d03d7dcd757d8896c47fecb 313 SUPERFAMILY SSF53850 91 295 4.11E-33 T 12-10-2018 UA74_05475 4df6288e7d03d7dcd757d8896c47fecb 313 SUPERFAMILY SSF46785 7 111 9.58E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_05475 4df6288e7d03d7dcd757d8896c47fecb 313 Gene3D G3DSA:1.10.10.10 4 92 8.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_05475 4df6288e7d03d7dcd757d8896c47fecb 313 Gene3D G3DSA:3.40.190.10 171 270 4.1E-37 T 12-10-2018 UA74_05475 4df6288e7d03d7dcd757d8896c47fecb 313 Pfam PF03466 LysR substrate binding domain 90 295 6.7E-38 T 12-10-2018 IPR005119 LysR, substrate-binding UA74_05475 4df6288e7d03d7dcd757d8896c47fecb 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 5.7E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UA74_05475 4df6288e7d03d7dcd757d8896c47fecb 313 Gene3D G3DSA:3.40.190.10 94 284 4.1E-37 T 12-10-2018 UA74_28380 8317b46e64313315d602d3e8ebc2fb7c 209 Gene3D G3DSA:1.10.150.240 16 76 3.0E-6 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UA74_28380 8317b46e64313315d602d3e8ebc2fb7c 209 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 157 1.7E-12 T 12-10-2018 UA74_28380 8317b46e64313315d602d3e8ebc2fb7c 209 SUPERFAMILY SSF56784 5 200 3.45E-35 T 12-10-2018 IPR036412 HAD-like superfamily UA74_28380 8317b46e64313315d602d3e8ebc2fb7c 209 Gene3D G3DSA:3.40.50.1000 77 203 9.9E-18 T 12-10-2018 IPR023214 HAD superfamily UA74_24425 31c920e7335631ce8cb9590d1fc7ec4f 289 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 261 3.4E-74 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_24425 31c920e7335631ce8cb9590d1fc7ec4f 289 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 262 37.963 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_24425 31c920e7335631ce8cb9590d1fc7ec4f 289 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 261 1.2E-73 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UA74_24425 31c920e7335631ce8cb9590d1fc7ec4f 289 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 UA74_24425 31c920e7335631ce8cb9590d1fc7ec4f 289 Gene3D G3DSA:3.40.1180.10 4 256 1.5E-95 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 UA74_24425 31c920e7335631ce8cb9590d1fc7ec4f 289 SUPERFAMILY SSF64005 34 257 1.7E-83 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 UA74_23860 da75ca22e3dda2233645b3a7b5cb2a0a 107 Gene3D G3DSA:3.30.70.100 1 95 3.7E-30 T 12-10-2018 UA74_23860 da75ca22e3dda2233645b3a7b5cb2a0a 107 SUPERFAMILY SSF54909 3 107 6.43E-30 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_23860 da75ca22e3dda2233645b3a7b5cb2a0a 107 Pfam PF05336 L-rhamnose mutarotase 4 106 2.1E-28 T 12-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 UA74_20910 484c37d6accb84b0d4e122a3f976d5a8 275 SUPERFAMILY SSF56112 16 228 3.83E-16 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_06290 524f6bf2df61d95b74b3d4707b28973f 398 Pfam PF13560 Helix-turn-helix domain 3 60 1.8E-13 T 12-10-2018 UA74_06290 524f6bf2df61d95b74b3d4707b28973f 398 SMART SM00530 7 62 1.7E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_06290 524f6bf2df61d95b74b3d4707b28973f 398 Gene3D G3DSA:1.10.260.40 1 60 1.1E-12 T 12-10-2018 UA74_06290 524f6bf2df61d95b74b3d4707b28973f 398 SUPERFAMILY SSF47413 1 55 1.1E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_26235 80f5ed81a9b42838e60d4544344cfd6c 292 PRINTS PR00412 Epoxide hydrolase signature 36 54 2.1E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_26235 80f5ed81a9b42838e60d4544344cfd6c 292 PRINTS PR00412 Epoxide hydrolase signature 267 289 2.1E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_26235 80f5ed81a9b42838e60d4544344cfd6c 292 PRINTS PR00412 Epoxide hydrolase signature 117 130 2.1E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_26235 80f5ed81a9b42838e60d4544344cfd6c 292 PRINTS PR00412 Epoxide hydrolase signature 103 116 2.1E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_26235 80f5ed81a9b42838e60d4544344cfd6c 292 SUPERFAMILY SSF53474 5 292 4.8E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26235 80f5ed81a9b42838e60d4544344cfd6c 292 Gene3D G3DSA:3.40.50.1820 2 292 4.1E-75 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_26235 80f5ed81a9b42838e60d4544344cfd6c 292 Pfam PF00561 alpha/beta hydrolase fold 31 138 9.4E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_04750 e3f7362c46890a46b4d05e7c7ad8705c 297 Gene3D G3DSA:3.40.50.10090 59 196 4.0E-62 T 12-10-2018 UA74_04750 e3f7362c46890a46b4d05e7c7ad8705c 297 SUPERFAMILY SSF69618 28 290 4.19E-52 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_04750 e3f7362c46890a46b4d05e7c7ad8705c 297 Pfam PF02602 Uroporphyrinogen-III synthase HemD 41 281 5.4E-36 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UA74_04750 e3f7362c46890a46b4d05e7c7ad8705c 297 Gene3D G3DSA:3.40.50.10090 33 280 4.0E-62 T 12-10-2018 UA74_24480 9e8719a638ebcb5d38cebcd1ff02e36d 128 SUPERFAMILY SSF53927 26 98 1.43E-9 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UA74_24480 9e8719a638ebcb5d38cebcd1ff02e36d 128 Gene3D G3DSA:3.40.140.10 19 115 3.0E-7 T 12-10-2018 UA74_13650 a79b8379dde82c198c10d26f6f5ccbf1 190 SUPERFAMILY SSF48498 81 188 1.26E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_13650 a79b8379dde82c198c10d26f6f5ccbf1 190 Gene3D G3DSA:1.10.357.10 2 189 1.0E-53 T 12-10-2018 UA74_13650 a79b8379dde82c198c10d26f6f5ccbf1 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 2.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_13650 a79b8379dde82c198c10d26f6f5ccbf1 190 SUPERFAMILY SSF46689 8 86 3.69E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_21260 7bfbaa3e911cf7f2de86ef4e1c306757 352 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 349 7.5E-153 T 12-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 UA74_21260 7bfbaa3e911cf7f2de86ef4e1c306757 352 SMART SM01329 4 346 9.8E-158 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_21260 7bfbaa3e911cf7f2de86ef4e1c306757 352 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 344 2.1E-85 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UA74_21260 7bfbaa3e911cf7f2de86ef4e1c306757 352 Gene3D G3DSA:3.40.718.10 1 351 2.0E-118 T 12-10-2018 UA74_21260 7bfbaa3e911cf7f2de86ef4e1c306757 352 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 UA74_21260 7bfbaa3e911cf7f2de86ef4e1c306757 352 SUPERFAMILY SSF53659 1 349 9.54E-109 T 12-10-2018 UA74_18735 eb3f3bc9e9522c828ab61f631bf4a7b0 340 SUPERFAMILY SSF51735 31 281 1.23E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_18735 eb3f3bc9e9522c828ab61f631bf4a7b0 340 Gene3D G3DSA:3.40.50.720 28 320 3.9E-19 T 12-10-2018 UA74_18035 615fea1fb9369e511ed4a1dce4c2ec42 223 Gene3D G3DSA:2.70.50.50 37 222 1.2E-68 T 12-10-2018 UA74_18035 615fea1fb9369e511ed4a1dce4c2ec42 223 SUPERFAMILY SSF81296 37 222 5.6E-33 T 12-10-2018 IPR014756 Immunoglobulin E-set UA74_18035 615fea1fb9369e511ed4a1dce4c2ec42 223 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 37 219 1.4E-32 T 12-10-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal UA74_08785 ee26001ba2ba95a11b833cd02a27da4b 473 Pfam PF02447 GntP family permease 31 472 1.3E-138 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_08785 ee26001ba2ba95a11b833cd02a27da4b 473 PIRSF PIRSF002746 25 473 1.8E-139 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_08785 ee26001ba2ba95a11b833cd02a27da4b 473 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 34 473 2.4E-129 T 12-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UA74_00715 b511e9e10779ea97658a53cae70814bb 399 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 395 6.8E-123 T 12-10-2018 IPR011340 Cysteine desulfurase-related UA74_00715 b511e9e10779ea97658a53cae70814bb 399 Pfam PF00266 Aminotransferase class-V 21 234 2.1E-31 T 12-10-2018 IPR000192 Aminotransferase class V domain UA74_00715 b511e9e10779ea97658a53cae70814bb 399 Pfam PF00266 Aminotransferase class-V 295 391 1.3E-7 T 12-10-2018 IPR000192 Aminotransferase class V domain UA74_00715 b511e9e10779ea97658a53cae70814bb 399 Gene3D G3DSA:3.40.640.10 28 284 6.3E-122 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_00715 b511e9e10779ea97658a53cae70814bb 399 SUPERFAMILY SSF53383 3 398 6.19E-66 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_00715 b511e9e10779ea97658a53cae70814bb 399 Gene3D G3DSA:3.90.1150.10 18 395 6.3E-122 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_14560 765d7248b9b8986744e5df85712139e6 281 Gene3D G3DSA:3.40.50.11590 150 262 3.4E-7 T 12-10-2018 UA74_14560 765d7248b9b8986744e5df85712139e6 281 SUPERFAMILY SSF159713 85 260 1.57E-19 T 12-10-2018 UA74_14560 765d7248b9b8986744e5df85712139e6 281 Pfam PF04016 Putative heavy-metal chelation 152 233 1.2E-10 T 12-10-2018 IPR007161 Putative heavy-metal chelation domain UA74_05865 3fab9c4f49766ca1998100a584bed50a 93 Pfam PF02583 Metal-sensitive transcriptional repressor 8 88 6.8E-31 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 UA74_05865 3fab9c4f49766ca1998100a584bed50a 93 Gene3D G3DSA:1.20.58.1000 4 93 2.5E-34 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily UA74_25190 c9b6d1ac11b85a8031614956964b9a01 555 SUPERFAMILY SSF50249 13 409 8.0E-88 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold UA74_25190 c9b6d1ac11b85a8031614956964b9a01 555 SMART SM00955 49 367 4.7E-60 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 UA74_25190 c9b6d1ac11b85a8031614956964b9a01 555 Pfam PF00773 RNB domain 49 354 5.9E-44 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 UA74_11675 bc5004248537075ae69a7675df17058d 440 Pfam PF13768 von Willebrand factor type A domain 51 208 1.2E-13 T 12-10-2018 IPR002035 von Willebrand factor, type A UA74_11675 bc5004248537075ae69a7675df17058d 440 SMART SM00327 48 219 3.3E-13 T 12-10-2018 IPR002035 von Willebrand factor, type A UA74_11675 bc5004248537075ae69a7675df17058d 440 SUPERFAMILY SSF53300 49 226 3.5E-22 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_11675 bc5004248537075ae69a7675df17058d 440 Gene3D G3DSA:1.20.120.1690 332 433 3.0E-36 T 12-10-2018 UA74_11675 bc5004248537075ae69a7675df17058d 440 Gene3D G3DSA:2.60.40.3670 6 328 3.5E-129 T 12-10-2018 UA74_11675 bc5004248537075ae69a7675df17058d 440 Gene3D G3DSA:3.40.50.410 47 230 3.5E-129 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_28515 a53f6f354a0042d220164e568d374240 51 Pfam PF04024 PspC domain 1 49 1.5E-13 T 12-10-2018 IPR007168 Phage shock protein, PspC, N-terminal UA74_11005 930ee880c9a3db9c073157fbeb1ec0df 413 SUPERFAMILY SSF53901 11 254 3.67E-57 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11005 930ee880c9a3db9c073157fbeb1ec0df 413 Gene3D G3DSA:3.40.47.10 263 411 1.8E-38 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11005 930ee880c9a3db9c073157fbeb1ec0df 413 Gene3D G3DSA:3.40.47.10 2 257 1.7E-55 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11005 930ee880c9a3db9c073157fbeb1ec0df 413 SUPERFAMILY SSF53901 217 408 1.1E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 UA74_11005 930ee880c9a3db9c073157fbeb1ec0df 413 SMART SM00825 Beta-ketoacyl synthase 10 412 5.2E-4 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UA74_11005 930ee880c9a3db9c073157fbeb1ec0df 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 11 246 3.6E-31 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UA74_11005 930ee880c9a3db9c073157fbeb1ec0df 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 277 365 9.8E-19 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UA74_15480 2dd40af6ded555384d6f53b142799c22 277 SUPERFAMILY SSF53335 47 239 3.29E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_15480 2dd40af6ded555384d6f53b142799c22 277 Gene3D G3DSA:1.10.8.10 3 68 2.3E-5 T 12-10-2018 UA74_15480 2dd40af6ded555384d6f53b142799c22 277 Gene3D G3DSA:3.40.50.150 69 272 1.6E-46 T 12-10-2018 UA74_15480 2dd40af6ded555384d6f53b142799c22 277 Pfam PF05175 Methyltransferase small domain 108 188 3.4E-11 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 UA74_15480 2dd40af6ded555384d6f53b142799c22 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 38 265 1.2E-43 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 UA74_15480 2dd40af6ded555384d6f53b142799c22 277 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 11 272 1.1E-121 T 12-10-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase UA74_27960 64e38885ec285fdecd2416551b6fc2a9 276 Pfam PF01614 Bacterial transcriptional regulator 142 263 2.2E-30 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_27960 64e38885ec285fdecd2416551b6fc2a9 276 SUPERFAMILY SSF46785 27 97 6.36E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_27960 64e38885ec285fdecd2416551b6fc2a9 276 Gene3D G3DSA:3.30.450.40 100 271 2.9E-52 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_27960 64e38885ec285fdecd2416551b6fc2a9 276 Gene3D G3DSA:1.10.10.10 26 99 7.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27960 64e38885ec285fdecd2416551b6fc2a9 276 Pfam PF09339 IclR helix-turn-helix domain 29 80 8.1E-20 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_27960 64e38885ec285fdecd2416551b6fc2a9 276 SUPERFAMILY SSF55781 84 267 1.44E-45 T 12-10-2018 UA74_27960 64e38885ec285fdecd2416551b6fc2a9 276 SMART SM00346 27 114 2.0E-24 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UA74_20295 e8671306538886ad09150413c764746c 199 Pfam PF03029 Conserved hypothetical ATP binding protein 24 191 2.1E-22 T 12-10-2018 IPR004130 GPN-loop GTPase UA74_20295 e8671306538886ad09150413c764746c 199 Gene3D G3DSA:3.40.50.300 17 193 2.1E-15 T 12-10-2018 UA74_20295 e8671306538886ad09150413c764746c 199 SUPERFAMILY SSF52540 18 194 1.08E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_10160 20616eaa6c17c6146fc67f6e4ff579b0 494 Pfam PF01757 Acyltransferase family 71 445 3.5E-14 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_26595 f5d465e0b216dcf4a6525a1e927de3b0 123 Pfam PF12005 Protein of unknown function (DUF3499) 8 105 1.4E-45 T 12-10-2018 IPR021888 Protein of unknown function DUF3499 UA74_17250 43cd948aebad2444b9f44b6509b1d303 422 Pfam PF06722 Protein of unknown function (DUF1205) 203 303 5.5E-24 T 12-10-2018 IPR010610 Domain of unknown function DUF1205 UA74_17250 43cd948aebad2444b9f44b6509b1d303 422 Gene3D G3DSA:3.40.50.2000 225 401 1.2E-151 T 12-10-2018 UA74_17250 43cd948aebad2444b9f44b6509b1d303 422 SUPERFAMILY SSF53756 1 414 1.02E-86 T 12-10-2018 UA74_17250 43cd948aebad2444b9f44b6509b1d303 422 TIGRFAM TIGR04516 glycosyl_450act: glycosyltransferase, activator-dependent family 1 418 1.9E-162 T 12-10-2018 IPR030953 Glycosyltransferase, activator-dependent family GO:0016757 UA74_17250 43cd948aebad2444b9f44b6509b1d303 422 Gene3D G3DSA:3.40.50.11450 1 413 1.2E-151 T 12-10-2018 UA74_01420 d66a190475ec6cc2b17b649c3716ef85 122 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 15 61 1.5E-7 T 12-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal UA74_01420 d66a190475ec6cc2b17b649c3716ef85 122 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 13 120 3.7E-26 T 12-10-2018 IPR021202 Apoptosis inhibitor Rv3654c-like UA74_02635 75f24cea64f25271ad46a1136ffe7d9c 328 SUPERFAMILY SSF103481 57 159 1.09E-11 T 12-10-2018 UA74_02635 75f24cea64f25271ad46a1136ffe7d9c 328 TIGRFAM TIGR00688 rarD: protein RarD 24 272 9.9E-56 T 12-10-2018 IPR004626 RarD protein GO:0005887 UA74_02635 75f24cea64f25271ad46a1136ffe7d9c 328 SUPERFAMILY SSF103481 221 298 1.07E-7 T 12-10-2018 UA74_02635 75f24cea64f25271ad46a1136ffe7d9c 328 Pfam PF00892 EamA-like transporter family 23 157 2.2E-9 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_05240 ac1471723bee3f400c60ff788aa4b4c7 254 Pfam PF01061 ABC-2 type transporter 7 203 3.1E-23 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_05240 ac1471723bee3f400c60ff788aa4b4c7 254 PIRSF PIRSF006648 3 254 5.6E-15 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_13915 397991b63fd2109ac0a63902e0f1bace 222 Pfam PF13250 Domain of unknown function (DUF4041) 133 187 1.1E-5 T 12-10-2018 IPR025280 Domain of unknown function DUF4041 UA74_03265 5e712649752df5cc8fb4a8ad0e90e79c 128 SMART SM00834 2 41 1.5E-14 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain UA74_03265 5e712649752df5cc8fb4a8ad0e90e79c 128 Pfam PF09723 Zinc ribbon domain 2 40 2.8E-14 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain UA74_03265 5e712649752df5cc8fb4a8ad0e90e79c 128 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 1.5E-20 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain UA74_28770 72f4431ea853c075b043d594b692283e 396 Pfam PF13692 Glycosyl transferases group 1 241 368 2.8E-10 T 12-10-2018 UA74_28770 72f4431ea853c075b043d594b692283e 396 SUPERFAMILY SSF53756 2 371 3.24E-12 T 12-10-2018 UA74_28770 72f4431ea853c075b043d594b692283e 396 Pfam PF13579 Glycosyl transferase 4-like domain 17 224 6.5E-9 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_14075 236c37993f77687e1176832a24e4548a 575 Gene3D G3DSA:1.20.1720.10 30 268 1.4E-51 T 12-10-2018 UA74_14075 236c37993f77687e1176832a24e4548a 575 SUPERFAMILY SSF103473 10 508 2.09E-73 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_14075 236c37993f77687e1176832a24e4548a 575 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 31 445 6.4E-78 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UA74_14075 236c37993f77687e1176832a24e4548a 575 PRINTS PR01036 Tetracycline resistance protein TetB signature 217 235 6.2E-9 T 12-10-2018 UA74_14075 236c37993f77687e1176832a24e4548a 575 PRINTS PR01036 Tetracycline resistance protein TetB signature 32 56 6.2E-9 T 12-10-2018 UA74_14075 236c37993f77687e1176832a24e4548a 575 PRINTS PR01036 Tetracycline resistance protein TetB signature 152 176 6.2E-9 T 12-10-2018 UA74_14075 236c37993f77687e1176832a24e4548a 575 PRINTS PR01036 Tetracycline resistance protein TetB signature 416 435 6.2E-9 T 12-10-2018 UA74_14075 236c37993f77687e1176832a24e4548a 575 PRINTS PR01036 Tetracycline resistance protein TetB signature 122 142 6.2E-9 T 12-10-2018 UA74_14075 236c37993f77687e1176832a24e4548a 575 Pfam PF07690 Major Facilitator Superfamily 34 425 1.5E-54 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_20880 c5b4f3a285b26db1942de88d98f02adc 169 SUPERFAMILY SSF46785 3 149 1.78E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20880 c5b4f3a285b26db1942de88d98f02adc 169 Gene3D G3DSA:1.10.10.10 1 78 3.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_20880 c5b4f3a285b26db1942de88d98f02adc 169 SMART SM00418 5 86 0.0018 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_20880 c5b4f3a285b26db1942de88d98f02adc 169 Pfam PF12840 Helix-turn-helix domain 7 63 2.4E-11 T 12-10-2018 UA74_12740 a1fdb5dbd6575c61ef049468f931c591 259 Gene3D G3DSA:3.40.50.150 13 206 6.0E-36 T 12-10-2018 UA74_12740 a1fdb5dbd6575c61ef049468f931c591 259 SUPERFAMILY SSF53335 14 197 5.41E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_12740 a1fdb5dbd6575c61ef049468f931c591 259 Pfam PF08241 Methyltransferase domain 55 145 6.0E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_04965 e7f925c350a3395bdfe1c274c49c46e0 252 Pfam PF09335 SNARE associated Golgi protein 47 174 1.2E-23 T 12-10-2018 IPR032816 SNARE associated Golgi protein UA74_04140 be52273f370ecdb3584c971a0a9f530c 203 Pfam PF14030 Protein of unknown function (DUF4245) 19 194 4.9E-41 T 12-10-2018 IPR025339 Protein of unknown function DUF4245 UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 SUPERFAMILY SSF51735 3 230 1.34E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 1.9E-6 T 12-10-2018 UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 9.8E-61 T 12-10-2018 UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.3E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.3E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.3E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.3E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.3E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.3E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 7.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 7.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 7.3E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 Gene3D G3DSA:3.40.50.720 2 234 1.0E-81 T 12-10-2018 UA74_11525 45a11c60ec52ebaa90fe17fda8099369 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UA74_26015 1bd3d099423c0d984b14002bbcfe7867 207 Gene3D G3DSA:1.10.357.10 3 199 7.3E-35 T 12-10-2018 UA74_26015 1bd3d099423c0d984b14002bbcfe7867 207 SUPERFAMILY SSF48498 91 192 6.16E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_26015 1bd3d099423c0d984b14002bbcfe7867 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 3.7E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_26015 1bd3d099423c0d984b14002bbcfe7867 207 SUPERFAMILY SSF46689 9 91 9.22E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_12820 3cb3ff66e82411ba610ead3b0756e6c3 661 Gene3D G3DSA:1.10.510.10 344 411 3.5E-6 T 12-10-2018 UA74_12820 3cb3ff66e82411ba610ead3b0756e6c3 661 Gene3D G3DSA:3.30.200.20 325 343 3.5E-6 T 12-10-2018 UA74_12820 3cb3ff66e82411ba610ead3b0756e6c3 661 Pfam PF03109 ABC1 family 207 310 1.2E-29 T 12-10-2018 IPR004147 UbiB domain UA74_12820 3cb3ff66e82411ba610ead3b0756e6c3 661 SUPERFAMILY SSF56112 189 408 1.37E-25 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_26765 46ef6fff87a8766d10f05419e4f08190 396 Pfam PF01139 tRNA-splicing ligase RtcB 28 396 5.3E-124 T 12-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 UA74_26765 46ef6fff87a8766d10f05419e4f08190 396 Gene3D G3DSA:3.90.1860.10 3 396 1.1E-108 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 UA74_26765 46ef6fff87a8766d10f05419e4f08190 396 SUPERFAMILY SSF103365 9 396 5.23E-125 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 UA74_01365 f520224c7279b7a4f825d5222b446968 425 Gene3D G3DSA:3.40.710.10 47 406 9.5E-88 T 12-10-2018 UA74_01365 f520224c7279b7a4f825d5222b446968 425 Pfam PF00144 Beta-lactamase 78 410 2.7E-72 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_01365 f520224c7279b7a4f825d5222b446968 425 SUPERFAMILY SSF56601 74 412 3.24E-85 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_02045 9df65c11be4e6cd74d179aaa115ed7bb 255 Gene3D G3DSA:1.10.10.10 121 255 4.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02045 9df65c11be4e6cd74d179aaa115ed7bb 255 SUPERFAMILY SSF46785 124 254 2.39E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_15975 bc29db39bb4ce48e315b4313ebb8086c 402 SUPERFAMILY SSF47413 2 70 2.82E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_15975 bc29db39bb4ce48e315b4313ebb8086c 402 Pfam PF13560 Helix-turn-helix domain 10 68 4.2E-12 T 12-10-2018 UA74_15975 bc29db39bb4ce48e315b4313ebb8086c 402 Gene3D G3DSA:1.10.260.40 2 71 9.8E-12 T 12-10-2018 UA74_15975 bc29db39bb4ce48e315b4313ebb8086c 402 SMART SM00530 12 68 2.9E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_27035 6bbd5ef74cbbe32d88d8e5a3e78b91f2 334 Pfam PF01261 Xylose isomerase-like TIM barrel 22 274 1.5E-36 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_27035 6bbd5ef74cbbe32d88d8e5a3e78b91f2 334 SUPERFAMILY SSF51658 8 318 2.75E-57 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_27035 6bbd5ef74cbbe32d88d8e5a3e78b91f2 334 Pfam PF07582 AP endonuclease family 2 C terminus 275 329 1.8E-23 T 12-10-2018 IPR011418 AP endonuclease, family 2, C-terminal UA74_27035 6bbd5ef74cbbe32d88d8e5a3e78b91f2 334 Gene3D G3DSA:3.20.20.150 2 323 2.1E-97 T 12-10-2018 UA74_22185 8e60c2824fee23bfeab4f660a878fafa 265 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 20 239 1.5E-19 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 UA74_22185 8e60c2824fee23bfeab4f660a878fafa 265 SUPERFAMILY SSF100950 15 255 1.79E-54 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_22185 8e60c2824fee23bfeab4f660a878fafa 265 Gene3D G3DSA:3.40.50.1360 18 254 8.0E-64 T 12-10-2018 UA74_21350 200c56f2ed0aac2ad61593522d1e2ac3 450 Pfam PF01032 FecCD transport family 129 445 3.6E-84 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_21350 200c56f2ed0aac2ad61593522d1e2ac3 450 SUPERFAMILY SSF81345 114 445 8.63E-75 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_21350 200c56f2ed0aac2ad61593522d1e2ac3 450 Gene3D G3DSA:1.10.3470.10 116 450 8.5E-91 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_11765 1d0c2e8c5fe2e1ccb8c8575853ef0e4c 96 Pfam PF04972 BON domain 22 84 1.8E-8 T 12-10-2018 IPR007055 BON domain UA74_28910 0ef42225d69c0599bcb53d63d0a25b23 128 SUPERFAMILY SSF54593 15 121 1.93E-15 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_28910 0ef42225d69c0599bcb53d63d0a25b23 128 Gene3D G3DSA:3.10.180.10 12 127 1.7E-10 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_00520 236bcb0e4a0fd1edf98b0e1bf0982452 274 Pfam PF02517 CAAX protease self-immunity 170 257 2.2E-14 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 UA74_11785 b000df0b9931e7f428ca3a87ace7a662 181 Pfam PF14325 Domain of unknown function (DUF4383) 20 143 3.5E-42 T 12-10-2018 IPR025492 Protein of unknown function DUF4383 UA74_01190 d8f59c8862821d72491bc6c531d15ffa 334 SUPERFAMILY SSF52540 19 238 1.18E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01190 d8f59c8862821d72491bc6c531d15ffa 334 Pfam PF02374 Anion-transporting ATPase 19 176 4.6E-17 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 UA74_08475 ed941bbeaea302793ce0c9bc044caacf 126 PIRSF PIRSF006910 1 125 5.2E-50 T 12-10-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted UA74_22335 8d298436550b9c50360db22118515599 440 Pfam PF07690 Major Facilitator Superfamily 28 382 5.2E-57 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_22335 8d298436550b9c50360db22118515599 440 SUPERFAMILY SSF103473 14 417 3.27E-77 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_22335 8d298436550b9c50360db22118515599 440 PIRSF PIRSF002808 1 429 3.7E-34 T 12-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 UA74_22335 8d298436550b9c50360db22118515599 440 Gene3D G3DSA:1.20.1250.20 10 421 1.2E-72 T 12-10-2018 UA74_04790 de99de55d01f30d1fcc1c61acd52d740 358 Gene3D G3DSA:1.10.287.70 35 138 3.2E-14 T 12-10-2018 UA74_04790 de99de55d01f30d1fcc1c61acd52d740 358 SUPERFAMILY SSF81324 42 163 1.44E-19 T 12-10-2018 UA74_04790 de99de55d01f30d1fcc1c61acd52d740 358 SUPERFAMILY SSF51735 142 286 3.59E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_04790 de99de55d01f30d1fcc1c61acd52d740 358 Pfam PF07885 Ion channel 47 126 6.9E-13 T 12-10-2018 IPR013099 Potassium channel domain UA74_04790 de99de55d01f30d1fcc1c61acd52d740 358 Gene3D G3DSA:3.40.50.720 139 279 3.2E-39 T 12-10-2018 UA74_04790 de99de55d01f30d1fcc1c61acd52d740 358 Pfam PF02254 TrkA-N domain 146 263 6.6E-26 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UA74_21805 3925a8226cb0fa4f33bf2cdd8b75b033 193 Pfam PF13302 Acetyltransferase (GNAT) domain 9 146 7.5E-26 T 12-10-2018 IPR000182 GNAT domain UA74_21805 3925a8226cb0fa4f33bf2cdd8b75b033 193 SUPERFAMILY SSF55729 3 170 9.33E-42 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_21805 3925a8226cb0fa4f33bf2cdd8b75b033 193 Gene3D G3DSA:3.40.630.30 1 185 9.4E-43 T 12-10-2018 UA74_03210 b8cf1e7247749b3dc6e4b26e964b948a 110 SUPERFAMILY SSF54909 1 101 4.45E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_03210 b8cf1e7247749b3dc6e4b26e964b948a 110 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 100 2.7E-14 T 12-10-2018 IPR009799 EthD domain UA74_03210 b8cf1e7247749b3dc6e4b26e964b948a 110 Gene3D G3DSA:3.30.70.100 1 103 2.3E-23 T 12-10-2018 UA74_03210 b8cf1e7247749b3dc6e4b26e964b948a 110 Pfam PF07110 EthD domain 16 82 3.5E-8 T 12-10-2018 IPR009799 EthD domain UA74_03820 f220dd39d8e5c7d2ed2031a344b1e0c0 555 Pfam PF09594 Glycosyltransferase family 87 85 318 9.8E-52 T 12-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 UA74_10820 e920b639217def9a87b9beb3c12da7a2 102 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 4 97 1.6E-13 T 12-10-2018 IPR008407 Branched-chain amino acid transport, AzlD UA74_10760 30a6c6cafe0ea910c8788dd3321dd26f 181 SUPERFAMILY SSF54197 17 169 1.55E-40 T 12-10-2018 IPR036265 HIT-like superfamily UA74_10760 30a6c6cafe0ea910c8788dd3321dd26f 181 Gene3D G3DSA:3.30.428.10 5 180 1.1E-56 T 12-10-2018 IPR036265 HIT-like superfamily UA74_10760 30a6c6cafe0ea910c8788dd3321dd26f 181 Pfam PF01230 HIT domain 53 145 6.7E-13 T 12-10-2018 IPR001310 Histidine triad (HIT) protein UA74_25365 85b88096b7b5bb38db6c1720ce2fa247 185 Pfam PF14016 Protein of unknown function (DUF4232) 45 164 7.8E-14 T 12-10-2018 IPR025326 Protein of unknown function DUF4232 UA74_23345 927db3e318a4b77aba3356d218801288 273 SUPERFAMILY SSF53474 8 267 2.63E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23345 927db3e318a4b77aba3356d218801288 273 Pfam PF12146 Serine aminopeptidase, S33 28 223 7.1E-20 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 UA74_23345 927db3e318a4b77aba3356d218801288 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 1.0E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_23345 927db3e318a4b77aba3356d218801288 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 1.0E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_23345 927db3e318a4b77aba3356d218801288 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.0E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_23345 927db3e318a4b77aba3356d218801288 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 1.0E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_23345 927db3e318a4b77aba3356d218801288 273 Gene3D G3DSA:3.40.50.1820 14 268 6.9E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_23345 927db3e318a4b77aba3356d218801288 273 PRINTS PR00412 Epoxide hydrolase signature 53 68 1.5E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_23345 927db3e318a4b77aba3356d218801288 273 PRINTS PR00412 Epoxide hydrolase signature 33 51 1.5E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_23345 927db3e318a4b77aba3356d218801288 273 PRINTS PR00412 Epoxide hydrolase signature 243 265 1.5E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_23345 927db3e318a4b77aba3356d218801288 273 PRINTS PR00412 Epoxide hydrolase signature 110 123 1.5E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_07740 1faad53b27dc86730453ada73518d682 265 Pfam PF13641 Glycosyltransferase like family 2 5 217 8.6E-8 T 12-10-2018 UA74_07740 1faad53b27dc86730453ada73518d682 265 Gene3D G3DSA:3.90.550.10 1 220 9.0E-17 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_07740 1faad53b27dc86730453ada73518d682 265 SUPERFAMILY SSF53448 5 223 4.22E-22 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_21765 64cbb3919883be15c2f0c272810b321e 393 SUPERFAMILY SSF54060 175 386 3.88E-55 T 12-10-2018 UA74_21765 64cbb3919883be15c2f0c272810b321e 393 Pfam PF04231 Endonuclease I 178 386 2.2E-40 T 12-10-2018 IPR007346 Endonuclease I GO:0004518 UA74_08450 e31ddd3d00d3b98b66c52c2b901968fe 236 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 91 181 4.1E-10 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain UA74_24415 140d311860565e53998939a389d05ebe 360 Pfam PF03773 Predicted permease 77 353 1.9E-49 T 12-10-2018 IPR005524 Predicted permease DUF318 UA74_13075 21f959dcfa1f056a483eb6b0f51ec45e 365 Pfam PF02361 Cobalt transport protein 16 227 7.5E-9 T 12-10-2018 IPR003339 ABC/ECF transporter, transmembrane component UA74_14625 480e6a9016ee5580bd3d08fb3300a05a 323 Pfam PF13569 Domain of unknown function (DUF4132) 87 240 7.3E-12 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 UA74_29025 b9c6945e1ba410bd6f671aefe7a01012 433 Gene3D G3DSA:1.10.443.10 217 422 2.8E-26 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_29025 b9c6945e1ba410bd6f671aefe7a01012 433 Gene3D G3DSA:1.10.150.130 64 205 1.6E-18 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_29025 b9c6945e1ba410bd6f671aefe7a01012 433 Pfam PF00589 Phage integrase family 230 406 3.0E-12 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_29025 b9c6945e1ba410bd6f671aefe7a01012 433 SUPERFAMILY SSF56349 70 411 3.24E-41 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_03435 c3d3900204f7d6dbc9defc1302136db9 286 SUPERFAMILY SSF51556 19 273 3.41E-78 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_03435 c3d3900204f7d6dbc9defc1302136db9 286 PIRSF PIRSF005902 5 276 1.4E-72 T 12-10-2018 IPR001130 TatD family GO:0016788 UA74_03435 c3d3900204f7d6dbc9defc1302136db9 286 Gene3D G3DSA:3.20.20.140 16 274 4.8E-82 T 12-10-2018 UA74_03435 c3d3900204f7d6dbc9defc1302136db9 286 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 21 272 4.1E-79 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 UA74_03435 c3d3900204f7d6dbc9defc1302136db9 286 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 208 224 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 UA74_03435 c3d3900204f7d6dbc9defc1302136db9 286 Pfam PF01026 TatD related DNase 21 271 1.1E-71 T 12-10-2018 IPR001130 TatD family GO:0016788 UA74_21200 96dfd8dd2704874e545ba5f351e9674e 117 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 24 107 2.5E-29 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane UA74_21200 96dfd8dd2704874e545ba5f351e9674e 117 Pfam PF12823 Domain of unknown function (DUF3817) 22 109 4.1E-27 T 12-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane UA74_03325 dd6aeee70fa2bf19b2ba484247b71dbb 311 Gene3D G3DSA:3.20.20.100 1 311 1.0E-80 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_03325 dd6aeee70fa2bf19b2ba484247b71dbb 311 Pfam PF00248 Aldo/keto reductase family 15 302 5.4E-52 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_03325 dd6aeee70fa2bf19b2ba484247b71dbb 311 SUPERFAMILY SSF51430 2 305 6.81E-69 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_01170 ab2a70edf973cf637ec926dc7337c681 253 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 16 232 6.9E-26 T 12-10-2018 UA74_25685 fc5c7ec9fda590a55efe468fb8354d08 293 Pfam PF00892 EamA-like transporter family 6 140 1.5E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_25685 fc5c7ec9fda590a55efe468fb8354d08 293 Pfam PF00892 EamA-like transporter family 151 285 5.3E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_25685 fc5c7ec9fda590a55efe468fb8354d08 293 SUPERFAMILY SSF103481 41 143 2.88E-10 T 12-10-2018 UA74_25685 fc5c7ec9fda590a55efe468fb8354d08 293 SUPERFAMILY SSF103481 213 289 5.36E-10 T 12-10-2018 UA74_28460 af833869d60bff0ee8660aa02ea50c8a 208 Pfam PF05331 Protein of unknown function (DUF742) 97 208 2.6E-32 T 12-10-2018 IPR007995 Protein of unknown function DUF742 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 SUPERFAMILY SSF48613 10 217 1.67E-54 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 Pfam PF01126 Heme oxygenase 11 210 1.5E-49 T 12-10-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 PIRSF PIRSF000343 1 220 1.4E-58 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 Gene3D G3DSA:1.20.910.10 9 220 2.0E-60 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 10 35 7.2E-24 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 45 70 7.2E-24 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 123 144 7.2E-24 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 165 186 7.2E-24 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 197 215 7.2E-24 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_29745 2f69e7553a8cabbce57115a8aa386414 234 PRINTS PR00088 Haem oxygenase signature 70 95 7.2E-24 T 12-10-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 UA74_06795 b5b50ec3dbdfa6029ce93bf3f62ca1aa 119 Gene3D G3DSA:3.40.1660.10 12 69 9.9E-13 T 12-10-2018 UA74_06795 b5b50ec3dbdfa6029ce93bf3f62ca1aa 119 SUPERFAMILY SSF159501 12 67 5.23E-14 T 12-10-2018 UA74_09220 0749cb95b394479465718afc7a40f25d 182 SUPERFAMILY SSF47240 39 176 9.19E-34 T 12-10-2018 IPR009078 Ferritin-like superfamily UA74_09220 0749cb95b394479465718afc7a40f25d 182 Pfam PF14530 Domain of unknown function (DUF4439) 43 179 1.5E-34 T 12-10-2018 IPR029447 Domain of unknown function DUF4439 UA74_09220 0749cb95b394479465718afc7a40f25d 182 Gene3D G3DSA:1.20.1260.10 37 168 3.7E-37 T 12-10-2018 IPR012347 Ferritin-like UA74_26795 3f171b9f1f37d76e53a58bcb37e98206 172 Pfam PF04138 GtrA-like protein 27 158 1.1E-20 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 UA74_19660 963a7db0523a6dbb9306e12ecb2a16e6 258 Gene3D G3DSA:3.40.50.1820 1 256 3.1E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19660 963a7db0523a6dbb9306e12ecb2a16e6 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 2.6E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19660 963a7db0523a6dbb9306e12ecb2a16e6 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.6E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19660 963a7db0523a6dbb9306e12ecb2a16e6 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.6E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19660 963a7db0523a6dbb9306e12ecb2a16e6 258 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 2.6E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_19660 963a7db0523a6dbb9306e12ecb2a16e6 258 SUPERFAMILY SSF53474 7 257 1.76E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_19660 963a7db0523a6dbb9306e12ecb2a16e6 258 Pfam PF00561 alpha/beta hydrolase fold 21 122 1.0E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_04700 7a3399207e0126c50d828e587dbcc169 391 Gene3D G3DSA:2.130.10.10 233 390 8.4E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_04700 7a3399207e0126c50d828e587dbcc169 391 Pfam PF13360 PQQ-like domain 279 363 2.2E-4 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat UA74_04700 7a3399207e0126c50d828e587dbcc169 391 Gene3D G3DSA:2.130.10.10 11 208 1.7E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_04700 7a3399207e0126c50d828e587dbcc169 391 SUPERFAMILY SSF50998 47 361 1.96E-6 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily UA74_26530 1ccb3beeff84feac75bfce245ea36cae 586 SUPERFAMILY SSF69322 346 572 1.24E-5 T 12-10-2018 UA74_26530 1ccb3beeff84feac75bfce245ea36cae 586 Pfam PF10646 Sporulation and spore germination 182 291 8.5E-9 T 12-10-2018 IPR019606 GerMN domain UA74_26530 1ccb3beeff84feac75bfce245ea36cae 586 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 334 585 3.9E-41 T 12-10-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal UA74_26530 1ccb3beeff84feac75bfce245ea36cae 586 SMART SM00909 209 297 2.5E-8 T 12-10-2018 IPR019606 GerMN domain UA74_20625 582b5298fc1f920e715e81763931c7fc 429 Gene3D G3DSA:3.40.190.10 151 421 7.5E-113 T 12-10-2018 UA74_20625 582b5298fc1f920e715e81763931c7fc 429 Pfam PF13416 Bacterial extracellular solute-binding protein 59 355 8.2E-28 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_20625 582b5298fc1f920e715e81763931c7fc 429 Gene3D G3DSA:3.40.190.10 42 372 7.5E-113 T 12-10-2018 UA74_20625 582b5298fc1f920e715e81763931c7fc 429 SUPERFAMILY SSF53850 28 427 5.43E-59 T 12-10-2018 UA74_13220 b67abf6a1c63ca6b5ef2880082dd42e4 339 Pfam PF01497 Periplasmic binding protein 71 303 7.1E-16 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_13220 b67abf6a1c63ca6b5ef2880082dd42e4 339 Gene3D G3DSA:3.40.50.1980 42 182 2.3E-38 T 12-10-2018 UA74_13220 b67abf6a1c63ca6b5ef2880082dd42e4 339 Gene3D G3DSA:3.40.50.1980 185 339 1.0E-38 T 12-10-2018 UA74_13220 b67abf6a1c63ca6b5ef2880082dd42e4 339 SUPERFAMILY SSF53807 49 313 1.14E-46 T 12-10-2018 UA74_18605 1c5cb26e5295d3f901eace3289312215 653 Pfam PF07593 ASPIC and UnbV 573 631 1.1E-7 T 12-10-2018 IPR011519 ASPIC/UnbV UA74_18605 1c5cb26e5295d3f901eace3289312215 653 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 294 368 5.9E-7 T 12-10-2018 UA74_18605 1c5cb26e5295d3f901eace3289312215 653 SUPERFAMILY SSF69318 70 539 1.57E-50 T 12-10-2018 UA74_00550 d46490acb2753a71d0025ae8466c08b9 521 PIRSF PIRSF006446 1 489 5.2E-132 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UA74_00550 d46490acb2753a71d0025ae8466c08b9 521 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 475 9.9E-165 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UA74_20110 087ab5372c3f4ef8b7d8543da770dffb 237 Pfam PF06912 Protein of unknown function (DUF1275) 2 214 5.8E-35 T 12-10-2018 IPR010699 Protein of unknown function DUF1275 UA74_12485 3d6b309de66c8e688b529c3c988a6363 295 SUPERFAMILY SSF56059 118 269 3.06E-10 T 12-10-2018 UA74_29820 01245171c2231b614a4ee34a9365be65 613 Pfam PF00350 Dynamin family 50 203 1.2E-13 T 12-10-2018 IPR022812 Dynamin superfamily UA74_29820 01245171c2231b614a4ee34a9365be65 613 SUPERFAMILY SSF52540 44 279 9.19E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29820 01245171c2231b614a4ee34a9365be65 613 Gene3D G3DSA:3.40.50.300 50 284 1.2E-25 T 12-10-2018 UA74_24095 d517f9b4d5294102e0c0c1659d33a8a8 200 SUPERFAMILY SSF46689 3 80 7.7E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_24095 d517f9b4d5294102e0c0c1659d33a8a8 200 Gene3D G3DSA:1.10.357.10 11 199 5.4E-45 T 12-10-2018 UA74_26560 3eb2569ec08ad46c4fe68a58bdd55792 925 SUPERFAMILY SSF53474 594 658 1.87E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_12155 30168d6ed2d8c8f0b0e29f19bbba28be 571 Gene3D G3DSA:2.115.10.20 83 189 3.0E-10 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_12155 30168d6ed2d8c8f0b0e29f19bbba28be 571 Gene3D G3DSA:2.115.10.20 190 317 6.1E-7 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_12155 30168d6ed2d8c8f0b0e29f19bbba28be 571 SUPERFAMILY SSF75005 165 354 1.04E-16 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UA74_18815 c2fb228f9cbbe988e63aa0525c5c02e4 373 SUPERFAMILY SSF103481 220 296 1.16E-9 T 12-10-2018 UA74_18815 c2fb228f9cbbe988e63aa0525c5c02e4 373 SUPERFAMILY SSF103481 45 141 8.37E-15 T 12-10-2018 UA74_18815 c2fb228f9cbbe988e63aa0525c5c02e4 373 Pfam PF00892 EamA-like transporter family 152 293 4.0E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_18815 c2fb228f9cbbe988e63aa0525c5c02e4 373 Pfam PF00892 EamA-like transporter family 11 141 1.2E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_23175 1aead46eb5193e7d87152c1ba091be1e 513 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 9 491 4.4E-60 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 UA74_23175 1aead46eb5193e7d87152c1ba091be1e 513 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 9 472 4.1E-78 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 UA74_09520 e5af5a860a8467571e0f6fe1868dcd1b 165 Pfam PF00583 Acetyltransferase (GNAT) family 39 116 3.0E-12 T 12-10-2018 IPR000182 GNAT domain UA74_09520 e5af5a860a8467571e0f6fe1868dcd1b 165 SUPERFAMILY SSF55729 2 123 6.0E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_09520 e5af5a860a8467571e0f6fe1868dcd1b 165 Gene3D G3DSA:3.40.630.30 3 139 1.5E-27 T 12-10-2018 UA74_08645 e678806d1c72d7444b038a435f4d194b 160 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 2 144 6.2E-50 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 UA74_08645 e678806d1c72d7444b038a435f4d194b 160 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 78.377 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 UA74_08645 e678806d1c72d7444b038a435f4d194b 160 Pfam PF03477 ATP cone domain 47 132 1.2E-14 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 UA74_14605 7872cf11187714a6455c2431add089b1 144 TIGRFAM TIGR04023 PPOX_MSMEG_5819: PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family 4 131 8.4E-32 T 12-10-2018 IPR024031 PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family KEGG: 00253+1.3.98.4|MetaCyc: PWY-7812 UA74_14605 7872cf11187714a6455c2431add089b1 144 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 100 3.2E-14 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_14605 7872cf11187714a6455c2431add089b1 144 Gene3D G3DSA:2.30.110.10 4 130 1.1E-20 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_14605 7872cf11187714a6455c2431add089b1 144 SUPERFAMILY SSF50475 6 138 3.74E-23 T 12-10-2018 UA74_09140 0b22c91f2cc3e4b1f796bc30b947e0a7 98 Gene3D G3DSA:3.30.70.100 1 98 1.1E-15 T 12-10-2018 UA74_09140 0b22c91f2cc3e4b1f796bc30b947e0a7 98 SUPERFAMILY SSF54909 1 93 2.61E-13 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_09140 0b22c91f2cc3e4b1f796bc30b947e0a7 98 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 2.2E-12 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_20980 1d562d86165ceb2268b265fc17f9ff1c 283 Pfam PF13560 Helix-turn-helix domain 11 72 1.8E-10 T 12-10-2018 UA74_20980 1d562d86165ceb2268b265fc17f9ff1c 283 Gene3D G3DSA:1.10.260.40 7 83 1.1E-6 T 12-10-2018 UA74_20980 1d562d86165ceb2268b265fc17f9ff1c 283 SUPERFAMILY SSF47413 11 68 1.3E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_20980 1d562d86165ceb2268b265fc17f9ff1c 283 SMART SM00530 15 70 0.0034 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_05690 bc830c275a9a79cc3db9909e5a73f6f3 176 Pfam PF00293 NUDIX domain 25 138 3.7E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_05690 bc830c275a9a79cc3db9909e5a73f6f3 176 Gene3D G3DSA:3.90.79.10 16 161 2.8E-20 T 12-10-2018 UA74_05690 bc830c275a9a79cc3db9909e5a73f6f3 176 SUPERFAMILY SSF55811 25 147 5.01E-22 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_05690 bc830c275a9a79cc3db9909e5a73f6f3 176 ProSitePatterns PS00893 Nudix box signature. 56 77 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_00530 555cea3383ed0f582bd2226081370552 394 Gene3D G3DSA:2.60.120.10 87 174 1.4E-6 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_00530 555cea3383ed0f582bd2226081370552 394 Pfam PF04209 homogentisate 1,2-dioxygenase 15 385 6.5E-17 T 12-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 UA74_00530 555cea3383ed0f582bd2226081370552 394 Gene3D G3DSA:2.60.120.10 269 364 7.1E-6 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_00530 555cea3383ed0f582bd2226081370552 394 SUPERFAMILY SSF51182 6 386 3.73E-89 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_23570 3551e0da460c9d17a3a53dfe0e23801e 113 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 111 2.0E-22 T 12-10-2018 IPR024412 Lsr2 UA74_23570 3551e0da460c9d17a3a53dfe0e23801e 113 Gene3D G3DSA:3.30.60.230 1 60 9.9E-25 T 12-10-2018 UA74_23570 3551e0da460c9d17a3a53dfe0e23801e 113 Gene3D G3DSA:1.20.890.50 79 113 2.3E-15 T 12-10-2018 UA74_23570 3551e0da460c9d17a3a53dfe0e23801e 113 Pfam PF11774 Lsr2 2 111 4.2E-40 T 12-10-2018 IPR024412 Lsr2 UA74_29995 5d41a68e209d8694e261ac61d37abb7c 463 Pfam PF05007 Mannosyltransferase (PIG-M) 189 379 4.3E-6 T 12-10-2018 IPR007704 GPI mannosyltransferase 1 GO:0006506|GO:0016021|GO:0016758 Reactome: R-HSA-162710 UA74_29995 5d41a68e209d8694e261ac61d37abb7c 463 PIRSF PIRSF010361 3 461 9.3E-75 T 12-10-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane UA74_25400 6e3d5d64c4bc2994e4ff544b188fa4ba 216 Pfam PF04973 Nicotinamide mononucleotide transporter 17 196 2.5E-44 T 12-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 UA74_25400 6e3d5d64c4bc2994e4ff544b188fa4ba 216 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 17 199 1.8E-13 T 12-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 UA74_21080 1451828620986dbdaf3284df4a399f1a 338 SUPERFAMILY SSF161098 90 323 9.03E-59 T 12-10-2018 IPR035906 MetI-like superfamily UA74_21080 1451828620986dbdaf3284df4a399f1a 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 331 2.2E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_21080 1451828620986dbdaf3284df4a399f1a 338 Gene3D G3DSA:1.10.3720.10 86 335 4.3E-68 T 12-10-2018 IPR035906 MetI-like superfamily UA74_02035 47a0af54d65ef2b048e3283af8bd5c37 256 SUPERFAMILY SSF58113 56 190 3.92E-6 T 12-10-2018 UA74_02035 47a0af54d65ef2b048e3283af8bd5c37 256 Gene3D G3DSA:1.10.287.700 127 228 3.0E-5 T 12-10-2018 UA74_02035 47a0af54d65ef2b048e3283af8bd5c37 256 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 71 168 2.0E-10 T 12-10-2018 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 UA74_18980 b2380bc52a6aa5b5497bd303812e1b8d 332 Gene3D G3DSA:3.40.50.1980 34 155 5.1E-16 T 12-10-2018 UA74_18980 b2380bc52a6aa5b5497bd303812e1b8d 332 SUPERFAMILY SSF53807 52 327 2.0E-39 T 12-10-2018 UA74_18980 b2380bc52a6aa5b5497bd303812e1b8d 332 Gene3D G3DSA:3.40.50.1980 161 331 3.2E-57 T 12-10-2018 UA74_18980 b2380bc52a6aa5b5497bd303812e1b8d 332 Pfam PF01497 Periplasmic binding protein 56 306 9.8E-22 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_10970 44b3dced95dbddfc2cbb45860fb52762 614 Pfam PF00733 Asparagine synthase 241 606 6.7E-80 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 UA74_10970 44b3dced95dbddfc2cbb45860fb52762 614 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 538 6.6E-150 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UA74_10970 44b3dced95dbddfc2cbb45860fb52762 614 SUPERFAMILY SSF52402 220 580 1.07E-61 T 12-10-2018 UA74_10970 44b3dced95dbddfc2cbb45860fb52762 614 Pfam PF13537 Glutamine amidotransferase domain 49 170 3.0E-43 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain UA74_10970 44b3dced95dbddfc2cbb45860fb52762 614 SUPERFAMILY SSF56235 1 225 5.4E-61 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_10970 44b3dced95dbddfc2cbb45860fb52762 614 Gene3D G3DSA:3.60.20.10 2 185 3.7E-62 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UA74_10970 44b3dced95dbddfc2cbb45860fb52762 614 PIRSF PIRSF001589 1 613 8.4E-149 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UA74_24940 d9f14863b7cbaf9d7268468184323e80 132 Pfam PF12270 Cytochrome c oxidase subunit IV 1 129 2.3E-51 T 12-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 UA74_24940 d9f14863b7cbaf9d7268468184323e80 132 PIRSF PIRSF017385 1 132 6.9E-49 T 12-10-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 UA74_10800 17ae7c3b027d35995da60c1b2292bfa0 134 SUPERFAMILY SSF88723 5 126 5.89E-14 T 12-10-2018 IPR029060 PIN-like domain superfamily UA74_10800 17ae7c3b027d35995da60c1b2292bfa0 134 Gene3D G3DSA:3.40.50.1010 3 125 1.9E-20 T 12-10-2018 UA74_10800 17ae7c3b027d35995da60c1b2292bfa0 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 129 9.857 T 12-10-2018 IPR022907 VapC family GO:0004540 UA74_10800 17ae7c3b027d35995da60c1b2292bfa0 134 Pfam PF01850 PIN domain 6 120 1.8E-9 T 12-10-2018 IPR002716 PIN domain UA74_27865 c8039dcf80a28168f1c4618d0ed9a204 187 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 126 181 6.4E-11 T 12-10-2018 UA74_27200 bbd7150f784e24cfbbf379efbdc8172e 844 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 58 99 1.2E-6 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_27200 bbd7150f784e24cfbbf379efbdc8172e 844 Pfam PF00361 Proton-conducting membrane transporter 125 416 1.4E-67 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_27200 bbd7150f784e24cfbbf379efbdc8172e 844 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 102 122 4.8E-34 T 12-10-2018 UA74_27200 bbd7150f784e24cfbbf379efbdc8172e 844 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 302 314 4.8E-34 T 12-10-2018 UA74_27200 bbd7150f784e24cfbbf379efbdc8172e 844 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 212 233 4.8E-34 T 12-10-2018 UA74_27200 bbd7150f784e24cfbbf379efbdc8172e 844 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 4.8E-34 T 12-10-2018 UA74_27200 bbd7150f784e24cfbbf379efbdc8172e 844 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 234 260 4.8E-34 T 12-10-2018 UA74_27200 bbd7150f784e24cfbbf379efbdc8172e 844 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 409 428 4.8E-34 T 12-10-2018 UA74_27200 bbd7150f784e24cfbbf379efbdc8172e 844 Pfam PF13244 Domain of unknown function (DUF4040) 600 664 8.4E-16 T 12-10-2018 IPR025383 Domain of unknown function DUF4040 UA74_09320 55283e674660864ae75b89f0f6905a62 87 Pfam PF16827 zinc-finger 20 75 7.0E-6 T 12-10-2018 IPR031795 Putative zinc-finger containing protein UA74_20785 9c0b2f0f0ae3ef4a55be14a55533a198 146 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 6 146 1.3E-25 T 12-10-2018 IPR011747 Conserved hypothetical protein CHP02241 UA74_20785 9c0b2f0f0ae3ef4a55be14a55533a198 146 Pfam PF06841 T4-like virus tail tube protein gp19 11 143 2.5E-26 T 12-10-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 UA74_22070 cd4622415c663ce6c753200f08655fa2 124 SUPERFAMILY SSF50475 6 68 8.18E-5 T 12-10-2018 UA74_22070 cd4622415c663ce6c753200f08655fa2 124 Pfam PF10012 Uncharacterized protein conserved in bacteria (DUF2255) 8 121 2.7E-38 T 12-10-2018 IPR016888 Uncharacterised conserved protein UCP028498 UA74_04380 4ccc88f195a47199f606dcb4fd8c0f7d 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 305 5.0E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_04380 4ccc88f195a47199f606dcb4fd8c0f7d 309 Gene3D G3DSA:1.10.3720.10 93 300 1.3E-21 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04380 4ccc88f195a47199f606dcb4fd8c0f7d 309 SUPERFAMILY SSF161098 100 286 8.5E-28 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04380 4ccc88f195a47199f606dcb4fd8c0f7d 309 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 70 2.1E-14 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UA74_01750 e03cd0a22cf9997f50d163f641ff5f68 455 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 169 316 3.4E-22 T 12-10-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain UA74_21155 5c5f03587b6061695dd5f249397fc9d3 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 54 14.25 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21155 5c5f03587b6061695dd5f249397fc9d3 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 54 8.0E-23 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21155 5c5f03587b6061695dd5f249397fc9d3 54 Pfam PF00471 Ribosomal protein L33 9 54 3.9E-16 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21155 5c5f03587b6061695dd5f249397fc9d3 54 SUPERFAMILY SSF57829 4 54 2.81E-17 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 UA74_21155 5c5f03587b6061695dd5f249397fc9d3 54 Gene3D G3DSA:2.20.28.120 1 54 1.5E-24 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_29425 dfcce5f14f92b0c9afa55f7fada3efc5 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 6.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_29425 dfcce5f14f92b0c9afa55f7fada3efc5 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 6.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_29425 dfcce5f14f92b0c9afa55f7fada3efc5 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 2.0E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_29425 dfcce5f14f92b0c9afa55f7fada3efc5 180 SUPERFAMILY SSF48498 79 178 1.11E-13 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_29425 dfcce5f14f92b0c9afa55f7fada3efc5 180 SUPERFAMILY SSF46689 4 73 1.49E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_29425 dfcce5f14f92b0c9afa55f7fada3efc5 180 Gene3D G3DSA:1.10.357.10 1 180 8.5E-51 T 12-10-2018 UA74_28080 f3421b91e8d49e76e06549fd7279f965 423 Gene3D G3DSA:1.10.287.1060 109 193 1.5E-7 T 12-10-2018 UA74_28080 f3421b91e8d49e76e06549fd7279f965 423 SUPERFAMILY SSF140453 111 187 3.53E-6 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_04930 3a1c4cc10efa9a19a3a9fee4c50a633c 300 Gene3D G3DSA:3.30.70.3040 43 160 1.2E-33 T 12-10-2018 UA74_04930 3a1c4cc10efa9a19a3a9fee4c50a633c 300 PIRSF PIRSF003097 1 300 1.7E-69 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 UA74_06470 3912d00f8795b5fb3f9ba2ac12c8734e 86 Gene3D G3DSA:1.10.1200.10 3 75 4.9E-8 T 12-10-2018 IPR036736 ACP-like superfamily UA74_06470 3912d00f8795b5fb3f9ba2ac12c8734e 86 SUPERFAMILY SSF47336 6 74 9.93E-9 T 12-10-2018 IPR036736 ACP-like superfamily UA74_09485 3021c07af8afe3aecb5956132242fe86 252 Pfam PF02511 Thymidylate synthase complementing protein 33 227 1.9E-53 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 UA74_09485 3021c07af8afe3aecb5956132242fe86 252 Gene3D G3DSA:3.30.70.3180 158 252 4.5E-34 T 12-10-2018 UA74_09485 3021c07af8afe3aecb5956132242fe86 252 SUPERFAMILY SSF69796 34 236 4.58E-60 T 12-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 UA74_09485 3021c07af8afe3aecb5956132242fe86 252 Gene3D G3DSA:3.30.70.3180 61 157 2.7E-23 T 12-10-2018 UA74_09485 3021c07af8afe3aecb5956132242fe86 252 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 9 240 25.963 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 UA74_09485 3021c07af8afe3aecb5956132242fe86 252 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 10 232 4.3E-59 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 UA74_24365 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 SUPERFAMILY SSF109604 30 238 1.51E-55 T 12-10-2018 UA74_24365 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 Pfam PF01966 HD domain 68 213 3.7E-19 T 12-10-2018 IPR006674 HD domain UA74_24365 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 Gene3D G3DSA:1.10.3210.10 10 416 3.6E-88 T 12-10-2018 UA74_24365 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 Pfam PF13286 Phosphohydrolase-associated domain 322 413 5.4E-22 T 12-10-2018 IPR026875 Phosphohydrolase-associated domain UA74_24365 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 31 415 1.9E-79 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 UA74_24365 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 SMART SM00471 64 223 4.5E-12 T 12-10-2018 IPR003607 HD/PDEase domain UA74_24365 d2ca3743e0f758f4dd8f15e1cd1fd83b 423 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 5 415 31.265 T 12-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 UA74_18890 31a8e876177ebcb2b2c2a22bd6428a3c 466 Gene3D G3DSA:3.40.50.360 269 464 2.5E-44 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_18890 31a8e876177ebcb2b2c2a22bd6428a3c 466 SUPERFAMILY SSF52218 279 449 1.31E-34 T 12-10-2018 IPR029039 Flavoprotein-like superfamily UA74_18890 31a8e876177ebcb2b2c2a22bd6428a3c 466 Pfam PF03358 NADPH-dependent FMN reductase 280 420 1.2E-28 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UA74_00850 fb0b73fd73ee4654e886ce2d7d8cb0cd 328 SUPERFAMILY SSF48179 175 272 4.76E-20 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UA74_00850 fb0b73fd73ee4654e886ce2d7d8cb0cd 328 Gene3D G3DSA:1.10.3660.10 175 277 6.5E-85 T 12-10-2018 UA74_00850 fb0b73fd73ee4654e886ce2d7d8cb0cd 328 SUPERFAMILY SSF51735 7 171 3.95E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_00850 fb0b73fd73ee4654e886ce2d7d8cb0cd 328 Pfam PF02153 Prephenate dehydrogenase 31 246 2.0E-39 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 UA74_00850 fb0b73fd73ee4654e886ce2d7d8cb0cd 328 Gene3D G3DSA:3.40.50.720 7 174 6.5E-85 T 12-10-2018 UA74_13080 054bf498abf5f83a214845203d88ad8c 406 SUPERFAMILY SSF56059 115 310 5.83E-23 T 12-10-2018 UA74_13080 054bf498abf5f83a214845203d88ad8c 406 Gene3D G3DSA:3.30.1490.20 111 189 2.5E-7 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UA74_13080 054bf498abf5f83a214845203d88ad8c 406 Gene3D G3DSA:3.30.470.20 223 330 3.5E-7 T 12-10-2018 UA74_27405 3922eb6e05049cd2317b4369098e7e15 297 SUPERFAMILY SSF53720 15 263 1.44E-45 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_27405 3922eb6e05049cd2317b4369098e7e15 297 Gene3D G3DSA:3.40.605.10 10 297 6.8E-54 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_27405 3922eb6e05049cd2317b4369098e7e15 297 Pfam PF00171 Aldehyde dehydrogenase family 33 264 7.2E-40 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_00180 1400f90496b056599031943afd1c3f4f 219 Gene3D G3DSA:3.40.50.720 5 219 7.1E-46 T 12-10-2018 UA74_00180 1400f90496b056599031943afd1c3f4f 219 Pfam PF13460 NAD(P)H-binding 10 196 1.1E-41 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_00180 1400f90496b056599031943afd1c3f4f 219 SUPERFAMILY SSF51735 5 207 1.1E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_23355 5a4096e3c327840038081d7c6e49fbba 146 Pfam PF13463 Winged helix DNA-binding domain 50 106 7.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_23355 5a4096e3c327840038081d7c6e49fbba 146 SUPERFAMILY SSF46785 21 144 1.74E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_23355 5a4096e3c327840038081d7c6e49fbba 146 SMART SM00347 34 133 2.0E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_23355 5a4096e3c327840038081d7c6e49fbba 146 Gene3D G3DSA:1.10.10.10 13 146 5.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18620 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Pfam PF00732 GMC oxidoreductase 8 258 2.2E-16 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 UA74_18620 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Gene3D G3DSA:3.50.50.60 158 298 4.8E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_18620 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Gene3D G3DSA:3.50.50.60 5 138 5.2E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_18620 f5df5d7d94eeaa782d32b7f8e76dcc58 563 SUPERFAMILY SSF51905 4 515 1.3E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_18620 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Pfam PF05199 GMC oxidoreductase 451 509 1.0E-15 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 UA74_18620 f5df5d7d94eeaa782d32b7f8e76dcc58 563 Gene3D G3DSA:3.50.50.60 418 517 6.7E-19 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_29225 c9dd70767164b444a371910a05040993 125 SUPERFAMILY SSF55718 67 124 8.95E-5 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily UA74_29225 c9dd70767164b444a371910a05040993 125 Gene3D G3DSA:3.30.1050.40 1 125 1.8E-53 T 12-10-2018 UA74_05780 7767465e745ef1da0e4c616a6f647c0e 312 SUPERFAMILY SSF52540 3 227 1.7E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_05780 7767465e745ef1da0e4c616a6f647c0e 312 Pfam PF00005 ABC transporter 21 163 1.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_05780 7767465e745ef1da0e4c616a6f647c0e 312 Gene3D G3DSA:3.40.50.300 1 236 2.8E-71 T 12-10-2018 UA74_05780 7767465e745ef1da0e4c616a6f647c0e 312 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_05780 7767465e745ef1da0e4c616a6f647c0e 312 SMART SM00382 29 239 3.0E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_05415 3270a9f6453f48397c12beacb719b97f 240 Pfam PF01061 ABC-2 type transporter 3 161 2.4E-6 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_22235 0b2bd6ddf7a2a046c8f9df35f567666b 364 Pfam PF01032 FecCD transport family 39 359 2.5E-90 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_22235 0b2bd6ddf7a2a046c8f9df35f567666b 364 Gene3D G3DSA:1.10.3470.10 26 364 1.1E-96 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_22235 0b2bd6ddf7a2a046c8f9df35f567666b 364 SUPERFAMILY SSF81345 22 359 2.75E-77 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_27860 4425a390cbd06ed1688b713ccdc14122 155 SUPERFAMILY SSF54593 4 146 3.32E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_27860 4425a390cbd06ed1688b713ccdc14122 155 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 144 3.2E-5 T 12-10-2018 IPR028973 PhnB-like UA74_27860 4425a390cbd06ed1688b713ccdc14122 155 Gene3D G3DSA:3.10.180.10 9 155 6.5E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_23165 29b455bdfc264d4b7b1211d36ac9c1d2 270 PIRSF PIRSF017393 1 269 8.7E-86 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_23165 29b455bdfc264d4b7b1211d36ac9c1d2 270 Pfam PF04672 S-adenosyl methyltransferase 10 268 1.2E-79 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_23165 29b455bdfc264d4b7b1211d36ac9c1d2 270 SUPERFAMILY SSF53335 13 252 2.15E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_23165 29b455bdfc264d4b7b1211d36ac9c1d2 270 Gene3D G3DSA:3.40.50.150 1 268 4.9E-94 T 12-10-2018 UA74_24820 93ed64080c0e5758b40a27f46cced500 174 Pfam PF16473 3' exoribonuclease, RNase T-like 2 155 2.2E-18 T 12-10-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain UA74_24820 93ed64080c0e5758b40a27f46cced500 174 SUPERFAMILY SSF53098 4 154 2.88E-6 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_24820 93ed64080c0e5758b40a27f46cced500 174 Gene3D G3DSA:3.30.420.10 1 167 3.6E-64 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_24820 93ed64080c0e5758b40a27f46cced500 174 Hamap MF_00977 3'-5' exoribonuclease. 1 159 42.873 T 12-10-2018 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 UA74_27480 e4096753d53073c46fc4bcc3b0f7f3e4 448 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 327 6.1E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_19905 acd7126f11ba09a18bde3d02924034d4 380 SMART SM00327 216 378 2.6E-7 T 12-10-2018 IPR002035 von Willebrand factor, type A UA74_19905 acd7126f11ba09a18bde3d02924034d4 380 SUPERFAMILY SSF53300 217 358 7.19E-18 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_19905 acd7126f11ba09a18bde3d02924034d4 380 Pfam PF05762 VWA domain containing CoxE-like protein 154 371 1.5E-53 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like UA74_19905 acd7126f11ba09a18bde3d02924034d4 380 Gene3D G3DSA:3.40.50.410 215 378 1.3E-10 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_28630 67a3d637ce6712d195855cb473fb2b06 373 SUPERFAMILY SSF53383 7 372 1.71E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_28630 67a3d637ce6712d195855cb473fb2b06 373 Gene3D G3DSA:3.90.1150.10 1 370 6.9E-143 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_28630 67a3d637ce6712d195855cb473fb2b06 373 Pfam PF00155 Aminotransferase class I and II 10 370 1.3E-63 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UA74_28630 67a3d637ce6712d195855cb473fb2b06 373 Gene3D G3DSA:3.40.640.10 23 270 6.9E-143 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_13975 eac4336f8429fef5b4b5de077db0ac47 225 SUPERFAMILY SSF53335 50 193 7.91E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_13975 eac4336f8429fef5b4b5de077db0ac47 225 Gene3D G3DSA:3.40.50.150 33 222 4.4E-21 T 12-10-2018 UA74_13975 eac4336f8429fef5b4b5de077db0ac47 225 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 80 133 2.9E-10 T 12-10-2018 UA74_02570 95dc045518d409ee197c3c8bca1265a0 257 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 115 236 2.2E-44 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02570 95dc045518d409ee197c3c8bca1265a0 257 Gene3D G3DSA:3.30.460.80 69 217 1.1E-47 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02570 95dc045518d409ee197c3c8bca1265a0 257 SUPERFAMILY SSF143243 101 253 1.31E-49 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02570 95dc045518d409ee197c3c8bca1265a0 257 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 116 237 1.2E-44 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02570 95dc045518d409ee197c3c8bca1265a0 257 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 85 245 29.709 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_02570 95dc045518d409ee197c3c8bca1265a0 257 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 165 226 4.0E-21 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_17490 1f2afa04fcee6708bea96cbef66bfc67 248 SUPERFAMILY SSF48371 15 228 2.7E-41 T 12-10-2018 IPR016024 Armadillo-type fold UA74_17490 1f2afa04fcee6708bea96cbef66bfc67 248 Pfam PF08713 DNA alkylation repair enzyme 12 227 6.3E-61 T 12-10-2018 IPR014825 DNA alkylation repair enzyme UA74_17490 1f2afa04fcee6708bea96cbef66bfc67 248 Gene3D G3DSA:1.25.10.90 2 239 7.7E-44 T 12-10-2018 UA74_25240 3af251cb1e9f1e871dfadd9afe26e7e7 81 Pfam PF10944 Protein of unknown function (DUF2630) 3 81 9.2E-26 T 12-10-2018 IPR020311 Uncharacterised protein family, Rv0898c UA74_25240 3af251cb1e9f1e871dfadd9afe26e7e7 81 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 19 81 9.0E-9 T 12-10-2018 IPR020311 Uncharacterised protein family, Rv0898c UA74_28355 aca1206755dd14163eb5890505e735be 165 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 34 139 2.0E-6 T 12-10-2018 IPR024495 Protein of unknown function DUF2771 UA74_28355 aca1206755dd14163eb5890505e735be 165 Pfam PF10969 Protein of unknown function (DUF2771) 27 145 2.3E-20 T 12-10-2018 IPR024495 Protein of unknown function DUF2771 UA74_12490 a30ceb21806af55beb0599b4444f27b9 159 SUPERFAMILY SSF46785 33 145 1.27E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_12490 a30ceb21806af55beb0599b4444f27b9 159 Pfam PF12802 MarR family 26 79 1.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_12490 a30ceb21806af55beb0599b4444f27b9 159 SMART SM00418 30 104 0.0082 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_12490 a30ceb21806af55beb0599b4444f27b9 159 Gene3D G3DSA:1.10.10.10 2 91 1.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04295 291a9be48156d7fb7e564726d21bf5f0 238 SUPERFAMILY SSF47413 32 84 1.21E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_25010 2e44703aadaa5e775b9f1d3bb8a4137c 242 Pfam PF11241 Protein of unknown function (DUF3043) 63 231 3.0E-60 T 12-10-2018 IPR021403 Protein of unknown function DUF3043 UA74_03215 2b4f3629059e79f60cd2d365074efbc1 202 Pfam PF03458 UPF0126 domain 90 159 9.8E-17 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 UA74_03215 2b4f3629059e79f60cd2d365074efbc1 202 Pfam PF03458 UPF0126 domain 4 78 3.1E-22 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 UA74_22565 94063f038b0920e598e4460b39c2399b 250 SUPERFAMILY SSF51735 2 192 3.57E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_22565 94063f038b0920e598e4460b39c2399b 250 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 169 7.3E-22 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_22565 94063f038b0920e598e4460b39c2399b 250 Gene3D G3DSA:3.40.50.720 2 223 3.1E-52 T 12-10-2018 UA74_13030 e812fbfdf95eee2a0384a848bf81360f 241 Pfam PF13490 Putative zinc-finger 3 37 8.1E-6 T 12-10-2018 IPR027383 Putative zinc-finger UA74_16655 94d31def9bced8f247da32cd70baf296 155 Gene3D G3DSA:1.10.10.10 2 84 1.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16655 94d31def9bced8f247da32cd70baf296 155 SUPERFAMILY SSF46785 12 93 1.03E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_16655 94d31def9bced8f247da32cd70baf296 155 Pfam PF12802 MarR family 19 78 1.8E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_28180 a0778050bdbe74a7978157302355247c 948 Gene3D G3DSA:3.40.50.300 137 353 1.5E-6 T 12-10-2018 UA74_28180 a0778050bdbe74a7978157302355247c 948 SUPERFAMILY SSF52540 378 597 1.57E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_28180 a0778050bdbe74a7978157302355247c 948 Gene3D G3DSA:3.40.50.300 361 656 1.2E-53 T 12-10-2018 UA74_28180 a0778050bdbe74a7978157302355247c 948 Pfam PF01580 FtsK/SpoIIIE family 392 594 1.0E-20 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UA74_03155 290b62a8827c5266f43d3532133c9802 327 PRINTS PR00075 Fatty acid desaturase family 1 signature 68 90 3.5E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_03155 290b62a8827c5266f43d3532133c9802 327 PRINTS PR00075 Fatty acid desaturase family 1 signature 91 111 3.5E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_03155 290b62a8827c5266f43d3532133c9802 327 PRINTS PR00075 Fatty acid desaturase family 1 signature 271 285 3.5E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_03155 290b62a8827c5266f43d3532133c9802 327 PRINTS PR00075 Fatty acid desaturase family 1 signature 228 249 3.5E-19 T 12-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 UA74_03155 290b62a8827c5266f43d3532133c9802 327 Pfam PF00487 Fatty acid desaturase 68 286 9.8E-19 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_18935 acd309d048830ec6fc7270ab66867e63 172 Pfam PF14015 Protein of unknown function (DUF4231) 38 123 5.7E-8 T 12-10-2018 IPR025325 Protein of unknown function DUF4231 UA74_06800 09979b9ce7245877a3e91736ba76bb6c 91 SMART SM00530 10 65 2.2E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_06800 09979b9ce7245877a3e91736ba76bb6c 91 Gene3D G3DSA:1.10.260.40 3 84 1.3E-12 T 12-10-2018 UA74_06800 09979b9ce7245877a3e91736ba76bb6c 91 Pfam PF13560 Helix-turn-helix domain 7 66 1.8E-12 T 12-10-2018 UA74_06800 09979b9ce7245877a3e91736ba76bb6c 91 SUPERFAMILY SSF47413 5 64 3.38E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_20145 23bcf165669b6b1f38648e55c4a1f9e8 377 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 92 319 2.6E-31 T 12-10-2018 IPR018713 Domain of unknown function DUF2236 UA74_27175 0faf159b92ff326083ecd0ef7fc876d8 88 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 81 1.2E-6 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 UA74_02625 d47cf8d0f02c9ce49e02e938a8b4c7e0 545 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 19 535 17.454 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 UA74_02625 d47cf8d0f02c9ce49e02e938a8b4c7e0 545 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 167 533 5.1E-113 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 UA74_02625 d47cf8d0f02c9ce49e02e938a8b4c7e0 545 Pfam PF00361 Proton-conducting membrane transporter 187 480 1.2E-75 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_01705 f91873fca1e6b4b8d2a90abf5c7dd1ff 430 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 84 135 1.0E-6 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UA74_01705 f91873fca1e6b4b8d2a90abf5c7dd1ff 430 SUPERFAMILY SSF56349 84 388 2.09E-51 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_01705 f91873fca1e6b4b8d2a90abf5c7dd1ff 430 Gene3D G3DSA:1.10.150.130 80 188 4.4E-21 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_01705 f91873fca1e6b4b8d2a90abf5c7dd1ff 430 Pfam PF00589 Phage integrase family 206 382 4.0E-15 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_01705 f91873fca1e6b4b8d2a90abf5c7dd1ff 430 Gene3D G3DSA:1.10.443.10 191 395 4.7E-36 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_26950 ca1a0ce55ccc6f2280fda707174b7bae 203 Pfam PF12079 Protein of unknown function (DUF3558) 21 197 9.6E-28 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_22035 67d8ed8e06bf0773f1b1917a96ae5a96 228 Gene3D G3DSA:1.10.3630.10 1 216 1.6E-20 T 12-10-2018 IPR038261 Golgi phosphoprotein 3-like domain superfamily UA74_22035 67d8ed8e06bf0773f1b1917a96ae5a96 228 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 9 205 9.2E-42 T 12-10-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 UA74_04355 b7bd637890a313548922b7cfcd955738 370 Gene3D G3DSA:3.90.79.10 150 251 1.3E-18 T 12-10-2018 UA74_04355 b7bd637890a313548922b7cfcd955738 370 Pfam PF00293 NUDIX domain 154 236 2.4E-12 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_04355 b7bd637890a313548922b7cfcd955738 370 SUPERFAMILY SSF55811 152 355 5.38E-22 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_04355 b7bd637890a313548922b7cfcd955738 370 PRINTS PR00502 NUDIX hydrolase family signature 181 195 4.1E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_04355 b7bd637890a313548922b7cfcd955738 370 PRINTS PR00502 NUDIX hydrolase family signature 195 210 4.1E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_19225 e5fe567f688fa7a4ea2d536c5bb93a7e 302 Pfam PF13803 Domain of unknown function (DUF4184) 2 135 6.4E-30 T 12-10-2018 IPR025238 Protein of unknown function DUF4184 UA74_14215 524c5e905e4b8e4017973761a397233d 460 Gene3D G3DSA:3.40.50.720 11 165 2.3E-10 T 12-10-2018 UA74_14215 524c5e905e4b8e4017973761a397233d 460 SUPERFAMILY SSF51735 73 152 6.63E-7 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_23805 e6464b22de130b5eafb60d9a804a9024 383 SUPERFAMILY SSF51735 4 155 1.48E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_23805 e6464b22de130b5eafb60d9a804a9024 383 SUPERFAMILY SSF55347 137 287 3.05E-12 T 12-10-2018 UA74_23805 e6464b22de130b5eafb60d9a804a9024 383 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 127 2.4E-17 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UA74_23805 e6464b22de130b5eafb60d9a804a9024 383 Gene3D G3DSA:3.30.360.10 141 285 3.2E-20 T 12-10-2018 UA74_23805 e6464b22de130b5eafb60d9a804a9024 383 Gene3D G3DSA:3.40.50.720 2 140 1.2E-29 T 12-10-2018 UA74_21785 ced3bd1e9210e34c6ec40c57eabb2fc7 264 Pfam PF14011 EspG family 9 250 5.6E-59 T 12-10-2018 IPR025734 EspG family UA74_23025 ac1c4983beb6a6b179fe97d6ba18bd77 62 Pfam PF04149 Domain of unknown function (DUF397) 8 60 1.1E-20 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_16085 02271d9f17a3b169f2a073fce6c350cd 214 Pfam PF01478 Type IV leader peptidase family 71 184 3.2E-12 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 UA74_10700 c4a1e12e051a27b9d010c6526224aa84 143 Gene3D G3DSA:3.10.180.10 3 143 1.9E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_10700 c4a1e12e051a27b9d010c6526224aa84 143 SUPERFAMILY SSF54593 3 142 2.56E-7 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_20615 c671c799b862ab172bd2b0e19e8f222e 286 Pfam PF13460 NAD(P)H-binding 11 185 5.4E-22 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_20615 c671c799b862ab172bd2b0e19e8f222e 286 Gene3D G3DSA:3.90.25.10 138 269 8.7E-62 T 12-10-2018 UA74_20615 c671c799b862ab172bd2b0e19e8f222e 286 SUPERFAMILY SSF51735 6 246 6.32E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_20615 c671c799b862ab172bd2b0e19e8f222e 286 Gene3D G3DSA:3.40.50.720 8 267 8.7E-62 T 12-10-2018 UA74_05035 abcbe11a3ef3ba7c754fa50a1cc96802 527 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 87 93 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UA74_05035 abcbe11a3ef3ba7c754fa50a1cc96802 527 Pfam PF01555 DNA methylase 84 379 4.1E-46 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 UA74_05035 abcbe11a3ef3ba7c754fa50a1cc96802 527 SUPERFAMILY SSF53335 52 387 2.02E-68 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_05035 abcbe11a3ef3ba7c754fa50a1cc96802 527 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 84 96 3.7E-20 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 UA74_05035 abcbe11a3ef3ba7c754fa50a1cc96802 527 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 322 344 3.7E-20 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 UA74_05035 abcbe11a3ef3ba7c754fa50a1cc96802 527 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 118 137 3.7E-20 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 UA74_05035 abcbe11a3ef3ba7c754fa50a1cc96802 527 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 345 359 3.7E-20 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 UA74_00900 094e7f0501d6a2d398726bf1f3bcda34 910 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 868 901 2.7E-4 T 12-10-2018 UA74_00900 094e7f0501d6a2d398726bf1f3bcda34 910 Pfam PF00932 Lamin Tail Domain 36 170 8.6E-8 T 12-10-2018 IPR001322 Lamin tail domain UA74_00900 094e7f0501d6a2d398726bf1f3bcda34 910 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 509 802 1.1E-5 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase UA74_00900 094e7f0501d6a2d398726bf1f3bcda34 910 Gene3D G3DSA:3.60.10.10 506 809 4.5E-33 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_00900 094e7f0501d6a2d398726bf1f3bcda34 910 SUPERFAMILY SSF56219 507 809 3.02E-29 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_21535 9e8f3443a045218e70bf76decdbd9f80 394 SUPERFAMILY SSF63999 179 302 3.27E-10 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 UA74_14525 a5c39f8e372134494052c190e1df3e31 356 Gene3D G3DSA:3.10.180.10 7 307 2.3E-114 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_14525 a5c39f8e372134494052c190e1df3e31 356 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 154 270 5.7E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_14525 a5c39f8e372134494052c190e1df3e31 356 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 127 1.9E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_14525 a5c39f8e372134494052c190e1df3e31 356 SUPERFAMILY SSF54593 5 282 2.9E-49 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_14525 a5c39f8e372134494052c190e1df3e31 356 Gene3D G3DSA:3.10.180.10 67 214 2.3E-114 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_20005 9967c32ab3dc7e56ca34cfb2865a0c6f 126 Pfam PF01042 Endoribonuclease L-PSP 12 123 4.3E-24 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UA74_20005 9967c32ab3dc7e56ca34cfb2865a0c6f 126 SUPERFAMILY SSF55298 2 124 5.18E-32 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_20005 9967c32ab3dc7e56ca34cfb2865a0c6f 126 Gene3D G3DSA:3.30.1330.40 6 126 3.0E-34 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UA74_00630 7f5724038f9aad5a564752eaebafbcac 295 SUPERFAMILY SSF51679 19 292 1.96E-52 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_00630 7f5724038f9aad5a564752eaebafbcac 295 Gene3D G3DSA:3.20.20.30 1 292 2.8E-55 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_00630 7f5724038f9aad5a564752eaebafbcac 295 Pfam PF00296 Luciferase-like monooxygenase 21 232 6.8E-43 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_12990 57f1ec2b93ad8b25e75a49066993f466 238 SMART SM00382 45 229 5.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_12990 57f1ec2b93ad8b25e75a49066993f466 238 Gene3D G3DSA:3.40.50.300 13 237 8.1E-58 T 12-10-2018 UA74_12990 57f1ec2b93ad8b25e75a49066993f466 238 Pfam PF00005 ABC transporter 37 182 5.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_12990 57f1ec2b93ad8b25e75a49066993f466 238 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_12990 57f1ec2b93ad8b25e75a49066993f466 238 SUPERFAMILY SSF52540 16 231 2.15E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_00525 1a04776c56c5bd50a15a1f25d37cd28a 256 Pfam PF10615 Protein of unknown function (DUF2470) 172 243 4.1E-7 T 12-10-2018 IPR019595 Domain of unknown function DUF2470 UA74_00525 1a04776c56c5bd50a15a1f25d37cd28a 256 SUPERFAMILY SSF50475 14 252 7.45E-20 T 12-10-2018 UA74_00525 1a04776c56c5bd50a15a1f25d37cd28a 256 Gene3D G3DSA:3.20.180.10 161 249 6.6E-15 T 12-10-2018 IPR037119 Haem oxygenase HugZ-like superfamily UA74_13355 dec9631991eabd9efe736e3ba90057ab 314 SUPERFAMILY SSF53613 1 302 5.61E-72 T 12-10-2018 IPR029056 Ribokinase-like UA74_13355 dec9631991eabd9efe736e3ba90057ab 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UA74_13355 dec9631991eabd9efe736e3ba90057ab 314 Gene3D G3DSA:3.40.1190.20 1 308 4.1E-84 T 12-10-2018 IPR029056 Ribokinase-like UA74_13355 dec9631991eabd9efe736e3ba90057ab 314 Pfam PF00294 pfkB family carbohydrate kinase 18 298 1.2E-47 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB UA74_13540 56046b288d48ed6aad5ba1065bbb889e 201 Pfam PF01575 MaoC like domain 70 160 5.1E-17 T 12-10-2018 IPR002539 MaoC-like dehydratase domain UA74_13540 56046b288d48ed6aad5ba1065bbb889e 201 Gene3D G3DSA:3.10.129.10 49 198 1.2E-42 T 12-10-2018 UA74_13540 56046b288d48ed6aad5ba1065bbb889e 201 SUPERFAMILY SSF54637 54 195 2.87E-32 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_30125 45a1b100da811219657601317b2bee46 399 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 297 389 1.6E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_30125 45a1b100da811219657601317b2bee46 399 SUPERFAMILY SSF55874 282 390 4.45E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_30125 45a1b100da811219657601317b2bee46 399 Gene3D G3DSA:3.30.565.10 270 389 5.9E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_11020 2ab967bf889bf784a80b5c14d280e99c 153 Pfam PF08592 Domain of unknown function (DUF1772) 18 146 3.5E-14 T 12-10-2018 UA74_13175 4c6dff5f3e531593ea4f8d726c8888bb 349 Gene3D G3DSA:1.20.1530.20 4 311 2.6E-106 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily UA74_13175 4c6dff5f3e531593ea4f8d726c8888bb 349 Pfam PF01758 Sodium Bile acid symporter family 45 222 2.3E-42 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 UA74_11070 792e09a0b25029a800eb175b7edc2064 124 Gene3D G3DSA:3.10.180.10 1 118 3.1E-33 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_11070 792e09a0b25029a800eb175b7edc2064 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 114 1.0E-9 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_11070 792e09a0b25029a800eb175b7edc2064 124 SUPERFAMILY SSF54593 1 122 1.02E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_09135 541d28d86898f645a4e81ee94dc08943 164 Pfam PF13673 Acetyltransferase (GNAT) domain 73 158 1.7E-14 T 12-10-2018 IPR000182 GNAT domain UA74_09135 541d28d86898f645a4e81ee94dc08943 164 Gene3D G3DSA:3.40.630.30 16 158 3.2E-34 T 12-10-2018 UA74_09135 541d28d86898f645a4e81ee94dc08943 164 SUPERFAMILY SSF55729 25 159 1.12E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_05020 6e3fa591c8c8d29829e516266ac68e65 474 Gene3D G3DSA:3.40.50.300 271 466 2.2E-14 T 12-10-2018 UA74_24855 53d2cfe6dfac961a5c7e3c0a1af15381 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 145 2.3E-12 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase UA74_24855 53d2cfe6dfac961a5c7e3c0a1af15381 154 Gene3D G3DSA:3.30.530.20 3 146 3.2E-34 T 12-10-2018 IPR023393 START-like domain superfamily UA74_24855 53d2cfe6dfac961a5c7e3c0a1af15381 154 SUPERFAMILY SSF55961 4 146 1.48E-27 T 12-10-2018 UA74_07590 e9b1a310a02233281bad4002025b70da 609 SUPERFAMILY SSF48208 106 525 2.11E-55 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_07590 e9b1a310a02233281bad4002025b70da 609 Gene3D G3DSA:1.50.10.10 104 530 2.4E-42 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_07590 e9b1a310a02233281bad4002025b70da 609 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 154 495 4.0E-19 T 12-10-2018 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 Gene3D G3DSA:4.10.640.10 2 83 6.7E-26 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 TIGRFAM TIGR00165 S18: ribosomal protein bS18 14 77 6.5E-24 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 SUPERFAMILY SSF46911 7 80 2.09E-25 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 5.5E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 5.5E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 5.5E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 5.5E-18 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 Pfam PF01084 Ribosomal protein S18 26 75 1.2E-23 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 11 80 19.63 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21165 0fb803d9bfb7093501153241fd5f472b 83 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 77 5.0E-17 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_18465 505232ea6428d8d9f36fa329afef1b6e 302 Gene3D G3DSA:1.10.260.40 8 84 7.1E-8 T 12-10-2018 UA74_18465 505232ea6428d8d9f36fa329afef1b6e 302 Pfam PF13560 Helix-turn-helix domain 26 85 9.7E-10 T 12-10-2018 UA74_18465 505232ea6428d8d9f36fa329afef1b6e 302 SUPERFAMILY SSF47413 20 81 2.82E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_18465 505232ea6428d8d9f36fa329afef1b6e 302 SMART SM00530 28 83 1.8E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_24740 78eb41733ae09a2fcb8d91d443a7e5d2 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 3.6E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_11645 e3a611505a09c22b95be4ed2c3c32b75 417 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_11645 e3a611505a09c22b95be4ed2c3c32b75 417 PIRSF PIRSF000521 10 117 1.5E-9 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_11645 e3a611505a09c22b95be4ed2c3c32b75 417 PIRSF PIRSF000521 108 414 1.8E-43 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_11645 e3a611505a09c22b95be4ed2c3c32b75 417 Pfam PF00202 Aminotransferase class-III 12 412 5.5E-124 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_11645 e3a611505a09c22b95be4ed2c3c32b75 417 Gene3D G3DSA:3.40.640.10 48 311 1.2E-155 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_11645 e3a611505a09c22b95be4ed2c3c32b75 417 SUPERFAMILY SSF53383 11 412 4.03E-134 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_11645 e3a611505a09c22b95be4ed2c3c32b75 417 Gene3D G3DSA:3.90.1150.10 8 407 1.2E-155 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_27760 328e899e074e9dc2a1109cb6a604c9d9 215 Pfam PF09335 SNARE associated Golgi protein 40 162 1.1E-15 T 12-10-2018 IPR032816 SNARE associated Golgi protein UA74_03110 605041461c755ac84047d554f05970a0 145 Pfam PF08044 Domain of unknown function (DUF1707) 10 62 2.2E-19 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 UA74_13385 e64f8538f75c112b7a2ba42eda3575da 75 Pfam PF04149 Domain of unknown function (DUF397) 11 67 3.5E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_10445 2498c49436d80836ddfe3df5a4693fc4 150 SUPERFAMILY SSF52799 54 142 4.24E-17 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like UA74_10445 2498c49436d80836ddfe3df5a4693fc4 150 Gene3D G3DSA:3.90.190.10 52 148 7.8E-16 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like UA74_10220 973aa52dff47a3561fb56ee33ba46eb0 571 TIGRFAM TIGR04141 TIGR04141: sporadically distributed protein, TIGR04141 family 25 561 1.3E-96 T 12-10-2018 IPR026487 Sporadically distributed protein CHP04141 UA74_25985 b133b9cbbb685d93d5dd6b8ca700d63e 310 Pfam PF07681 DoxX 155 239 5.2E-19 T 12-10-2018 IPR032808 DoxX family UA74_23120 8c8c19ff9e48847ab27c369c38b09a06 634 SUPERFAMILY SSF69318 151 579 4.71E-14 T 12-10-2018 UA74_23120 8c8c19ff9e48847ab27c369c38b09a06 634 Gene3D G3DSA:2.60.40.10 53 142 5.6E-30 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_03065 3fa65aa9a5718601db0985d77891d286 65 Pfam PF04149 Domain of unknown function (DUF397) 7 58 1.5E-14 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_27620 9e58355eda0b32fb3d5d1e72c085c8c4 201 Pfam PF00805 Pentapeptide repeats (8 copies) 131 167 7.8E-12 T 12-10-2018 IPR001646 Pentapeptide repeat UA74_27620 9e58355eda0b32fb3d5d1e72c085c8c4 201 Gene3D G3DSA:2.160.20.100 21 201 8.6E-57 T 12-10-2018 UA74_27620 9e58355eda0b32fb3d5d1e72c085c8c4 201 SUPERFAMILY SSF141571 22 199 2.35E-44 T 12-10-2018 UA74_27620 9e58355eda0b32fb3d5d1e72c085c8c4 201 Pfam PF13599 Pentapeptide repeats (9 copies) 31 104 3.0E-9 T 12-10-2018 IPR001646 Pentapeptide repeat UA74_07735 ccfe90e5b85b9510a69d28626ad900d5 154 Gene3D G3DSA:3.30.530.20 1 139 2.8E-36 T 12-10-2018 IPR023393 START-like domain superfamily UA74_07735 ccfe90e5b85b9510a69d28626ad900d5 154 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 128 7.3E-17 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 UA74_07735 ccfe90e5b85b9510a69d28626ad900d5 154 SUPERFAMILY SSF55961 2 139 5.94E-25 T 12-10-2018 UA74_30035 cbcc1526fa770d8790fac02d9e0f1c89 281 Pfam PF13349 Putative adhesin 20 278 1.3E-12 T 12-10-2018 IPR025164 Putative adhesin UA74_13510 ec3e2674020e78d997cc24d97bc9393d 253 Pfam PF13458 Periplasmic binding protein 16 223 5.9E-28 T 12-10-2018 IPR028081 Leucine-binding protein domain UA74_13510 ec3e2674020e78d997cc24d97bc9393d 253 Gene3D G3DSA:3.40.50.2300 1 151 1.3E-32 T 12-10-2018 UA74_13510 ec3e2674020e78d997cc24d97bc9393d 253 SUPERFAMILY SSF53822 18 249 7.06E-27 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_03810 480042686fa8c3f93de48183545eba3d 382 SUPERFAMILY SSF56059 254 358 1.39E-9 T 12-10-2018 UA74_03810 480042686fa8c3f93de48183545eba3d 382 Gene3D G3DSA:3.30.470.20 266 373 4.2E-10 T 12-10-2018 UA74_28165 281f4cc50b3b325d790ceb85f4ee4926 594 SUPERFAMILY SSF53187 130 476 3.97E-62 T 12-10-2018 UA74_28165 281f4cc50b3b325d790ceb85f4ee4926 594 Gene3D G3DSA:3.40.630.10 128 486 6.8E-76 T 12-10-2018 UA74_28165 281f4cc50b3b325d790ceb85f4ee4926 594 SMART SM00631 135 467 3.9E-42 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_28165 281f4cc50b3b325d790ceb85f4ee4926 594 Pfam PF00246 Zinc carboxypeptidase 143 444 1.8E-46 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_28165 281f4cc50b3b325d790ceb85f4ee4926 594 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 368 381 5.4E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_28165 281f4cc50b3b325d790ceb85f4ee4926 594 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 300 308 5.4E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_28165 281f4cc50b3b325d790ceb85f4ee4926 594 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 199 213 5.4E-5 T 12-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UA74_09185 be9cfda4eabb99774706dacbbde4aebc 397 SUPERFAMILY SSF56112 121 343 5.74E-20 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_25680 908379a7e8e6a6d5631ffce5f2bb5796 65 Pfam PF04149 Domain of unknown function (DUF397) 8 60 1.5E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_07580 6f6d9539b3bfccf0275b1ba2f0debb94 154 SUPERFAMILY SSF54427 8 144 5.48E-6 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_01470 18aa02beba4ef2f5874a5a9cff2090c3 203 Gene3D G3DSA:3.40.630.30 29 200 1.5E-38 T 12-10-2018 UA74_01470 18aa02beba4ef2f5874a5a9cff2090c3 203 Pfam PF13302 Acetyltransferase (GNAT) domain 36 175 2.1E-23 T 12-10-2018 IPR000182 GNAT domain UA74_01470 18aa02beba4ef2f5874a5a9cff2090c3 203 SUPERFAMILY SSF55729 30 198 8.07E-39 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_21445 b0fb14928f02d79a5c3998684cb05a59 181 Gene3D G3DSA:3.40.630.30 2 165 1.3E-29 T 12-10-2018 UA74_21445 b0fb14928f02d79a5c3998684cb05a59 181 Pfam PF13302 Acetyltransferase (GNAT) domain 10 150 9.9E-21 T 12-10-2018 IPR000182 GNAT domain UA74_21445 b0fb14928f02d79a5c3998684cb05a59 181 SUPERFAMILY SSF55729 6 157 5.97E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_05170 db22e8a238cde72c873385bbff8ecdc4 527 Gene3D G3DSA:3.30.300.30 407 526 8.5E-29 T 12-10-2018 UA74_05170 db22e8a238cde72c873385bbff8ecdc4 527 Gene3D G3DSA:3.40.50.12780 1 406 1.2E-121 T 12-10-2018 UA74_05170 db22e8a238cde72c873385bbff8ecdc4 527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 12-10-2018 IPR020845 AMP-binding, conserved site UA74_05170 db22e8a238cde72c873385bbff8ecdc4 527 SUPERFAMILY SSF56801 6 521 4.06E-129 T 12-10-2018 UA74_05170 db22e8a238cde72c873385bbff8ecdc4 527 Pfam PF00501 AMP-binding enzyme 11 413 1.2E-89 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UA74_05170 db22e8a238cde72c873385bbff8ecdc4 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 512 6.0E-8 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UA74_05170 db22e8a238cde72c873385bbff8ecdc4 527 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 32 437 2.4E-113 T 12-10-2018 IPR010071 Amino acid adenylation domain UA74_25510 66fdafe96740f3ff9c26296468571628 106 Gene3D G3DSA:3.40.630.30 14 105 6.7E-25 T 12-10-2018 UA74_25510 66fdafe96740f3ff9c26296468571628 106 Pfam PF14542 GCN5-related N-acetyl-transferase 22 99 1.4E-23 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase UA74_25510 66fdafe96740f3ff9c26296468571628 106 SUPERFAMILY SSF55729 14 101 2.48E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_01560 22833ddde7b22c6559cddc5ff467adca 127 TIGRFAM TIGR00526 folB_dom: FolB domain 3 120 1.5E-33 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_01560 22833ddde7b22c6559cddc5ff467adca 127 SUPERFAMILY SSF55620 3 119 7.78E-36 T 12-10-2018 UA74_01560 22833ddde7b22c6559cddc5ff467adca 127 Pfam PF02152 Dihydroneopterin aldolase 5 115 8.2E-34 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_01560 22833ddde7b22c6559cddc5ff467adca 127 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 6.6E-38 T 12-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_01560 22833ddde7b22c6559cddc5ff467adca 127 SMART SM00905 5 117 1.3E-46 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UA74_01560 22833ddde7b22c6559cddc5ff467adca 127 Gene3D G3DSA:3.30.1130.10 1 119 2.2E-44 T 12-10-2018 UA74_10705 df7f5c6d18cbb5ab8f64341e59040b65 320 Pfam PF12679 ABC-2 family transporter protein 66 318 2.2E-14 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UA74_15255 3a08c29b1b6d71e1a24a234654cf5e73 384 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 297 379 1.9E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_15255 3a08c29b1b6d71e1a24a234654cf5e73 384 Pfam PF07730 Histidine kinase 184 245 6.7E-11 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_15255 3a08c29b1b6d71e1a24a234654cf5e73 384 SMART SM00387 291 382 4.4E-4 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_15255 3a08c29b1b6d71e1a24a234654cf5e73 384 Gene3D G3DSA:3.30.565.10 258 380 1.8E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_15255 3a08c29b1b6d71e1a24a234654cf5e73 384 SUPERFAMILY SSF55874 286 379 2.15E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_01295 862252ecd577edff5ba164a9d0de3edc 270 Pfam PF01925 Sulfite exporter TauE/SafE 150 261 8.8E-20 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_01295 862252ecd577edff5ba164a9d0de3edc 270 Pfam PF01925 Sulfite exporter TauE/SafE 11 128 4.1E-28 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_14245 46df8bd0287442e941beaa185047ab9e 153 Pfam PF12802 MarR family 39 98 2.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14245 46df8bd0287442e941beaa185047ab9e 153 SMART SM00347 33 136 6.5E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UA74_14245 46df8bd0287442e941beaa185047ab9e 153 SUPERFAMILY SSF46785 6 147 3.52E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_14245 46df8bd0287442e941beaa185047ab9e 153 Gene3D G3DSA:1.10.10.10 7 150 3.3E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_02955 086dd6f7527d8963946f09e21b60b382 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 6 96 21.369 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 UA74_02955 086dd6f7527d8963946f09e21b60b382 99 Pfam PF00276 Ribosomal protein L23 7 89 1.0E-31 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 UA74_02955 086dd6f7527d8963946f09e21b60b382 99 Gene3D G3DSA:3.30.70.330 5 96 3.8E-31 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily UA74_02955 086dd6f7527d8963946f09e21b60b382 99 SUPERFAMILY SSF54189 4 92 2.99E-31 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_08825 64118c4d0d27c58d58878912e7c85d28 150 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.514 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08825 64118c4d0d27c58d58878912e7c85d28 150 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 2.0E-29 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08825 64118c4d0d27c58d58878912e7c85d28 150 Gene3D G3DSA:3.30.1320.10 1 149 8.2E-29 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08825 64118c4d0d27c58d58878912e7c85d28 150 Pfam PF00886 Ribosomal protein S16 9 67 1.3E-22 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_08825 64118c4d0d27c58d58878912e7c85d28 150 SUPERFAMILY SSF54565 2 90 1.96E-31 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_03625 ed84bc69983836cb4be7751029dd9453 404 Pfam PF01566 Natural resistance-associated macrophage protein 14 369 4.5E-29 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UA74_10120 b7e91c7848ae4b4eb1c81104ef3dabaf 227 PIRSF PIRSF006324 3 226 4.2E-47 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 UA74_10120 b7e91c7848ae4b4eb1c81104ef3dabaf 227 Pfam PF01810 LysE type translocator 14 224 5.9E-30 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 UA74_02470 59c87a3be8596ff0c7de19c3a91c503b 453 Gene3D G3DSA:1.10.287.700 303 447 4.1E-7 T 12-10-2018 UA74_02470 59c87a3be8596ff0c7de19c3a91c503b 453 SUPERFAMILY SSF58104 174 340 7.46E-5 T 12-10-2018 UA74_00705 71bfaa86f3546fc1eb312c7ff28c3c1f 303 Pfam PF01061 ABC-2 type transporter 55 264 1.4E-24 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_08705 dca849d86073f8457c0c974f5b50573b 332 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 35 317 8.0E-74 T 12-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 UA74_08705 dca849d86073f8457c0c974f5b50573b 332 Pfam PF03812 2-keto-3-deoxygluconate permease 14 316 2.0E-107 T 12-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 UA74_14550 cac9f2989f23f94a9fc00b883a6e9dc3 256 Gene3D G3DSA:3.40.50.150 48 232 2.0E-14 T 12-10-2018 UA74_14550 cac9f2989f23f94a9fc00b883a6e9dc3 256 SUPERFAMILY SSF53335 51 232 1.5E-15 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_14550 cac9f2989f23f94a9fc00b883a6e9dc3 256 Pfam PF05175 Methyltransferase small domain 74 169 1.8E-5 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 UA74_29185 0326220208af595a3cb336de09430fd7 61 Pfam PF11273 Protein of unknown function (DUF3073) 2 60 1.5E-23 T 12-10-2018 IPR021426 Protein of unknown function DUF3073 UA74_06790 307fa61250f1ee41f640561d42c3f2ee 191 Gene3D G3DSA:1.10.10.60 1 48 6.8E-17 T 12-10-2018 UA74_06790 307fa61250f1ee41f640561d42c3f2ee 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 5.7E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06790 307fa61250f1ee41f640561d42c3f2ee 191 SUPERFAMILY SSF48498 71 187 3.37E-6 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_06790 307fa61250f1ee41f640561d42c3f2ee 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 2.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06790 307fa61250f1ee41f640561d42c3f2ee 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 2.1E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_06790 307fa61250f1ee41f640561d42c3f2ee 191 Gene3D G3DSA:1.10.357.10 49 191 4.9E-9 T 12-10-2018 UA74_06790 307fa61250f1ee41f640561d42c3f2ee 191 SUPERFAMILY SSF46689 2 58 8.03E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_03575 2a75103212937a77944346af5b616220 417 PRINTS PR01988 Putative bacilysin exporter bacE signature 269 286 6.7E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UA74_03575 2a75103212937a77944346af5b616220 417 PRINTS PR01988 Putative bacilysin exporter bacE signature 21 43 6.7E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UA74_03575 2a75103212937a77944346af5b616220 417 PRINTS PR01988 Putative bacilysin exporter bacE signature 177 194 6.7E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UA74_03575 2a75103212937a77944346af5b616220 417 PRINTS PR01988 Putative bacilysin exporter bacE signature 84 102 6.7E-5 T 12-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UA74_03575 2a75103212937a77944346af5b616220 417 SUPERFAMILY SSF103473 15 406 1.28E-42 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_03575 2a75103212937a77944346af5b616220 417 Pfam PF05977 Transmembrane secretion effector 15 399 3.9E-29 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_03575 2a75103212937a77944346af5b616220 417 Gene3D G3DSA:1.20.1250.20 12 404 7.3E-37 T 12-10-2018 UA74_20325 fdb06c6b98c9c96281fe91984fcaff08 402 Pfam PF01032 FecCD transport family 81 395 8.7E-76 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UA74_20325 fdb06c6b98c9c96281fe91984fcaff08 402 Gene3D G3DSA:1.10.3470.10 68 401 1.2E-84 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_20325 fdb06c6b98c9c96281fe91984fcaff08 402 SUPERFAMILY SSF81345 65 395 3.4E-65 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_15385 8ddda60fe5a12b5226a5fe12a02b2a1e 354 SUPERFAMILY SSF53474 44 262 7.56E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15385 8ddda60fe5a12b5226a5fe12a02b2a1e 354 Gene3D G3DSA:3.40.50.1820 30 342 2.7E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_15385 8ddda60fe5a12b5226a5fe12a02b2a1e 354 Pfam PF07224 Chlorophyllase 70 186 5.2E-5 T 12-10-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 UA74_27855 28ffd9d5c47709d1eb341e9d920a19ed 364 Gene3D G3DSA:1.10.10.10 39 100 6.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_27855 28ffd9d5c47709d1eb341e9d920a19ed 364 ProSitePatterns PS00894 DeoR-type HTH domain signature. 42 76 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_27855 28ffd9d5c47709d1eb341e9d920a19ed 364 Pfam PF13280 WYL domain 177 354 6.1E-26 T 12-10-2018 IPR026881 WYL domain UA74_27855 28ffd9d5c47709d1eb341e9d920a19ed 364 PIRSF PIRSF016838 33 360 5.4E-18 T 12-10-2018 IPR028349 Protein PafC UA74_27855 28ffd9d5c47709d1eb341e9d920a19ed 364 SUPERFAMILY SSF46785 39 98 1.45E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_27855 28ffd9d5c47709d1eb341e9d920a19ed 364 Pfam PF08279 HTH domain 42 97 5.3E-16 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 UA74_17705 614649165a97765f2ba65d26607710e3 395 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 6 340 7.0E-93 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 UA74_17705 614649165a97765f2ba65d26607710e3 395 Pfam PF09344 CT1975-like protein 7 355 1.9E-100 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 UA74_23725 dd1ed4547b4777bb952f353921dea2a8 181 Pfam PF11452 Protein of unknown function (DUF3000) 5 175 2.4E-69 T 12-10-2018 IPR021555 Protein of unknown function DUF3000 UA74_03270 beef9855ecdfa2a27605a522a272370c 220 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 23 202 3.1E-31 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase UA74_03270 beef9855ecdfa2a27605a522a272370c 220 SUPERFAMILY SSF100950 22 207 1.95E-36 T 12-10-2018 IPR037171 NagB/RpiA transferase-like UA74_03270 beef9855ecdfa2a27605a522a272370c 220 PIRSF PIRSF006806 19 205 3.9E-31 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase UA74_03270 beef9855ecdfa2a27605a522a272370c 220 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 23 202 1.2E-36 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase UA74_03270 beef9855ecdfa2a27605a522a272370c 220 Gene3D G3DSA:3.40.50.10420 21 214 4.4E-36 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily UA74_01530 fb891c6a3d362362a233b5458bcb3a03 61 Pfam PF04149 Domain of unknown function (DUF397) 7 59 9.2E-19 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_24055 cc9efa0424893fca52efecc76d971f75 286 Gene3D G3DSA:3.40.50.720 3 278 9.3E-33 T 12-10-2018 UA74_24055 cc9efa0424893fca52efecc76d971f75 286 SUPERFAMILY SSF51735 5 212 4.28E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_24055 cc9efa0424893fca52efecc76d971f75 286 Pfam PF00106 short chain dehydrogenase 7 142 3.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_28545 9594645188c02748c733e5f17c261338 935 SUPERFAMILY SSF48452 118 299 8.1E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_28545 9594645188c02748c733e5f17c261338 935 Gene3D G3DSA:1.25.40.10 86 298 1.9E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_28545 9594645188c02748c733e5f17c261338 935 Pfam PF12770 CHAT domain 633 918 2.6E-31 T 12-10-2018 IPR024983 CHAT domain UA74_28545 9594645188c02748c733e5f17c261338 935 SMART SM00028 158 191 0.11 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_28545 9594645188c02748c733e5f17c261338 935 SMART SM00028 198 231 40.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_26715 927c14de5e28bef9e7aa3c7f6a22c435 330 Gene3D G3DSA:3.40.50.300 38 293 6.7E-59 T 12-10-2018 UA74_26715 927c14de5e28bef9e7aa3c7f6a22c435 330 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_26715 927c14de5e28bef9e7aa3c7f6a22c435 330 Pfam PF00005 ABC transporter 57 195 2.9E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_26715 927c14de5e28bef9e7aa3c7f6a22c435 330 SMART SM00382 65 243 2.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_26715 927c14de5e28bef9e7aa3c7f6a22c435 330 SUPERFAMILY SSF52540 30 261 1.46E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_11260 f62f6797bbad976aef725f1e28dcb074 362 Gene3D G3DSA:1.10.620.20 21 355 3.5E-107 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 UA74_11260 f62f6797bbad976aef725f1e28dcb074 362 PIRSF PIRSF000355 15 362 4.1E-127 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11260 f62f6797bbad976aef725f1e28dcb074 362 Pfam PF00268 Ribonucleotide reductase, small chain 42 329 2.1E-85 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UA74_11260 f62f6797bbad976aef725f1e28dcb074 362 SUPERFAMILY SSF47240 26 333 5.8E-96 T 12-10-2018 IPR009078 Ferritin-like superfamily UA74_27590 ea910c380e2a0c587916bcc5ba2ba9b0 96 Pfam PF11222 Protein of unknown function (DUF3017) 16 89 6.3E-20 T 12-10-2018 IPR021385 Protein of unknown function DUF3017 UA74_12770 1078251a0cb25d147281a9eb0b6e0dd1 433 SUPERFAMILY SSF55874 293 416 4.98E-13 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_12770 1078251a0cb25d147281a9eb0b6e0dd1 433 Gene3D G3DSA:3.30.565.10 288 414 9.1E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_14340 42ed946d0c2856827089e519b929463d 182 SUPERFAMILY SSF46689 5 65 2.0E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_14340 42ed946d0c2856827089e519b929463d 182 SUPERFAMILY SSF48498 78 174 2.52E-5 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_14340 42ed946d0c2856827089e519b929463d 182 Gene3D G3DSA:1.10.357.10 2 182 5.2E-32 T 12-10-2018 UA74_14340 42ed946d0c2856827089e519b929463d 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 4.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_03245 ea6e1450683d90d846e68740e70c8094 74 Pfam PF14013 MT0933-like antitoxin protein 5 62 3.3E-9 T 12-10-2018 IPR028037 Antitoxin Rv0909/MT0933 UA74_02065 31ae67cffce45354ceacc0855521e2e3 64 Pfam PF04149 Domain of unknown function (DUF397) 8 59 6.3E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_26960 465a35666fb046714de1cb130b5c91cd 366 SUPERFAMILY SSF140459 9 174 1.73E-14 T 12-10-2018 UA74_26960 465a35666fb046714de1cb130b5c91cd 366 Pfam PF00823 PPE family 19 160 7.7E-10 T 12-10-2018 IPR000030 PPE family UA74_26960 465a35666fb046714de1cb130b5c91cd 366 Gene3D G3DSA:1.20.1260.20 15 176 3.7E-15 T 12-10-2018 IPR038332 PPE superfamily UA74_00375 e039131581f98c6cabc3d896c0d439bd 155 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 29 150 8.6E-36 T 12-10-2018 IPR019920 F420-binding domain, putative UA74_00375 e039131581f98c6cabc3d896c0d439bd 155 Gene3D G3DSA:2.30.110.10 19 152 1.2E-37 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_00375 e039131581f98c6cabc3d896c0d439bd 155 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 26 105 2.6E-15 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_00375 e039131581f98c6cabc3d896c0d439bd 155 SUPERFAMILY SSF50475 25 149 2.9E-31 T 12-10-2018 UA74_17805 5de5ec24c51416bca48d8c8da992c672 482 SUPERFAMILY SSF55874 273 347 2.48E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_17805 5de5ec24c51416bca48d8c8da992c672 482 Pfam PF07730 Histidine kinase 193 258 8.5E-16 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_10480 dc1c4e045c61d300ab0406677b625be4 148 SUPERFAMILY SSF55961 2 145 4.32E-33 T 12-10-2018 UA74_10480 dc1c4e045c61d300ab0406677b625be4 148 Gene3D G3DSA:3.30.530.20 3 147 1.4E-34 T 12-10-2018 IPR023393 START-like domain superfamily UA74_10480 dc1c4e045c61d300ab0406677b625be4 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 143 2.0E-20 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_23495 7614849bee53bbb4746d1f13233eed98 405 Pfam PF01594 AI-2E family transporter 34 355 1.9E-59 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like UA74_05605 402009abb129c7863d0aa47132cbd21c 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 1.4E-128 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane UA74_12245 88a6ef20bf881062dd6f2bf2a1190ecc 176 Gene3D G3DSA:1.10.10.10 12 103 4.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12245 88a6ef20bf881062dd6f2bf2a1190ecc 176 SUPERFAMILY SSF46785 51 127 2.04E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_28330 00745dbd0ad97add9fe66feeb4b65cf0 66 Pfam PF10745 Protein of unknown function (DUF2530) 1 65 2.3E-17 T 12-10-2018 IPR019681 Protein of unknown function DUF2530 UA74_21860 9d93f802f45422402049d83f84d9834f 421 Pfam PF01547 Bacterial extracellular solute-binding protein 49 331 4.8E-24 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_21860 9d93f802f45422402049d83f84d9834f 421 SUPERFAMILY SSF53850 25 419 4.61E-56 T 12-10-2018 UA74_21860 9d93f802f45422402049d83f84d9834f 421 Gene3D G3DSA:3.40.190.10 146 415 2.4E-105 T 12-10-2018 UA74_21860 9d93f802f45422402049d83f84d9834f 421 Gene3D G3DSA:3.40.190.10 37 367 2.4E-105 T 12-10-2018 UA74_09415 171c35acaa321401d7dbe49a2237e532 146 Gene3D G3DSA:1.25.40.10 91 146 2.6E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_25170 53fcd7733d708f9900f84d511fe190c4 172 Pfam PF04978 Protein of unknown function (DUF664) 18 168 2.1E-42 T 12-10-2018 IPR007061 Protein of unknown function DUF664 UA74_25170 53fcd7733d708f9900f84d511fe190c4 172 SUPERFAMILY SSF109854 3 167 5.04E-40 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_25170 53fcd7733d708f9900f84d511fe190c4 172 Gene3D G3DSA:1.20.120.450 3 171 8.1E-36 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_18930 99be310c6aebed77a396b0a9fefa9e96 120 Gene3D G3DSA:1.10.10.10 1 106 4.4E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18930 99be310c6aebed77a396b0a9fefa9e96 120 SUPERFAMILY SSF46785 3 101 3.91E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18930 99be310c6aebed77a396b0a9fefa9e96 120 SMART SM00418 2 84 2.3E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_18930 99be310c6aebed77a396b0a9fefa9e96 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 3.6E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_18930 99be310c6aebed77a396b0a9fefa9e96 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 3.6E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_18930 99be310c6aebed77a396b0a9fefa9e96 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 3.6E-10 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_18930 99be310c6aebed77a396b0a9fefa9e96 120 Pfam PF12840 Helix-turn-helix domain 4 63 4.9E-12 T 12-10-2018 UA74_05440 a92f0eab7f94131501dbb8b84059c57a 521 SUPERFAMILY SSF103473 1 516 1.96E-57 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_05440 a92f0eab7f94131501dbb8b84059c57a 521 Pfam PF07690 Major Facilitator Superfamily 37 428 4.9E-41 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_05440 a92f0eab7f94131501dbb8b84059c57a 521 Gene3D G3DSA:1.20.1250.20 283 516 8.7E-10 T 12-10-2018 UA74_05440 a92f0eab7f94131501dbb8b84059c57a 521 Gene3D G3DSA:1.20.1720.10 27 238 6.3E-37 T 12-10-2018 UA74_09420 a86714f3ab86dd0d3ab364ba3a7a304d 161 Pfam PF09335 SNARE associated Golgi protein 35 151 5.7E-8 T 12-10-2018 IPR032816 SNARE associated Golgi protein UA74_24840 4d3f5ec25af10f48da5a8cf77bd3231b 311 Gene3D G3DSA:3.30.420.40 116 287 2.1E-96 T 12-10-2018 UA74_24840 4d3f5ec25af10f48da5a8cf77bd3231b 311 Pfam PF00480 ROK family 2 305 4.6E-72 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_24840 4d3f5ec25af10f48da5a8cf77bd3231b 311 Gene3D G3DSA:3.30.420.40 1 300 2.1E-96 T 12-10-2018 UA74_24840 4d3f5ec25af10f48da5a8cf77bd3231b 311 SUPERFAMILY SSF53067 2 308 3.0E-63 T 12-10-2018 UA74_24840 4d3f5ec25af10f48da5a8cf77bd3231b 311 ProSitePatterns PS01125 ROK family signature. 124 151 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UA74_23405 d956dacb220fe93d810d81de2e30792c 290 Gene3D G3DSA:3.40.50.410 6 215 6.6E-13 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_23405 d956dacb220fe93d810d81de2e30792c 290 SUPERFAMILY SSF53300 13 185 8.38E-10 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_11960 df4c42c8e9eccf066bfd59f91d693b1e 403 Gene3D G3DSA:1.20.1250.20 215 392 4.0E-18 T 12-10-2018 UA74_11960 df4c42c8e9eccf066bfd59f91d693b1e 403 Gene3D G3DSA:1.20.1250.20 13 196 1.1E-16 T 12-10-2018 UA74_11960 df4c42c8e9eccf066bfd59f91d693b1e 403 Pfam PF07690 Major Facilitator Superfamily 17 223 3.2E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_11960 df4c42c8e9eccf066bfd59f91d693b1e 403 Pfam PF07690 Major Facilitator Superfamily 238 394 2.1E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_11960 df4c42c8e9eccf066bfd59f91d693b1e 403 SUPERFAMILY SSF103473 10 399 3.92E-36 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_28150 7314c84a3024f6ecb20f2a07253eaf9f 212 Pfam PF01596 O-methyltransferase 18 207 7.9E-37 T 12-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 UA74_28150 7314c84a3024f6ecb20f2a07253eaf9f 212 SUPERFAMILY SSF53335 33 211 1.21E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_28150 7314c84a3024f6ecb20f2a07253eaf9f 212 Gene3D G3DSA:3.40.50.150 8 211 1.5E-62 T 12-10-2018 UA74_26840 f8eb58db1f0937ea30741aa67cf1b7d9 231 Pfam PF01955 Adenosylcobinamide amidohydrolase 20 199 2.2E-48 T 12-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ UA74_08960 f439d27d46d382870f776d8fc3b992f6 308 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 262 288 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 UA74_08960 f439d27d46d382870f776d8fc3b992f6 308 Pfam PF01148 Cytidylyltransferase family 49 303 5.5E-55 T 12-10-2018 UA74_07900 11177131b9c99afea30d3fce20033204 259 Pfam PF14011 EspG family 10 252 1.1E-60 T 12-10-2018 IPR025734 EspG family UA74_20315 30a27d78891cd121600d1b546b47f3eb 477 PRINTS PR00359 B-class P450 signature 164 180 1.0E-6 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20315 30a27d78891cd121600d1b546b47f3eb 477 PRINTS PR00359 B-class P450 signature 118 129 1.0E-6 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20315 30a27d78891cd121600d1b546b47f3eb 477 PRINTS PR00359 B-class P450 signature 216 238 1.0E-6 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20315 30a27d78891cd121600d1b546b47f3eb 477 PRINTS PR00359 B-class P450 signature 357 366 1.0E-6 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20315 30a27d78891cd121600d1b546b47f3eb 477 SUPERFAMILY SSF48264 22 417 1.57E-58 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20315 30a27d78891cd121600d1b546b47f3eb 477 Gene3D G3DSA:1.10.630.10 29 427 8.0E-80 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_28895 764b6490509215f63647dba14cb99882 275 Pfam PF03301 Tryptophan 2,3-dioxygenase 16 273 9.9E-56 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 UA74_28895 764b6490509215f63647dba14cb99882 275 Gene3D G3DSA:1.20.58.480 19 275 3.9E-69 T 12-10-2018 UA74_28895 764b6490509215f63647dba14cb99882 275 SUPERFAMILY SSF140959 20 272 1.96E-73 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 UA74_28895 764b6490509215f63647dba14cb99882 275 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 14 275 34.902 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 PRINTS PR01576 Peptide deformylase signature 128 157 5.0E-32 T 12-10-2018 IPR023635 Peptide deformylase UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 PRINTS PR01576 Peptide deformylase signature 33 62 5.0E-32 T 12-10-2018 IPR023635 Peptide deformylase UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 PRINTS PR01576 Peptide deformylase signature 97 108 5.0E-32 T 12-10-2018 IPR023635 Peptide deformylase UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 PRINTS PR01576 Peptide deformylase signature 109 127 5.0E-32 T 12-10-2018 IPR023635 Peptide deformylase UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 Pfam PF01327 Polypeptide deformylase 4 158 2.0E-43 T 12-10-2018 IPR023635 Peptide deformylase UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 Hamap MF_00163 Peptide deformylase [def]. 2 170 28.36 T 12-10-2018 IPR023635 Peptide deformylase UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 10 164 2.5E-38 T 12-10-2018 IPR023635 Peptide deformylase UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 SUPERFAMILY SSF56420 1 164 7.2E-54 T 12-10-2018 IPR036821 Peptide deformylase superfamily UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 PIRSF PIRSF004749 1 178 1.9E-43 T 12-10-2018 IPR023635 Peptide deformylase UA74_01890 c37b593a6d05bef258fce3ed1f3ab9cd 193 Gene3D G3DSA:3.90.45.10 1 190 7.5E-64 T 12-10-2018 IPR036821 Peptide deformylase superfamily UA74_05955 a929a4f8e216f60c6e1152ab0e24834c 250 Pfam PF01061 ABC-2 type transporter 10 215 1.2E-31 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_05955 a929a4f8e216f60c6e1152ab0e24834c 250 PIRSF PIRSF006648 1 250 4.6E-50 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_27670 d437bcdf98d73cff2ed919df70a4118a 238 Pfam PF17270 Family of unknown function (DUF5336) 5 149 1.6E-23 T 12-10-2018 IPR035166 Protein of unknown function DUF5336 UA74_25895 5065b178493c961985a5d26c0ffdec2f 731 Gene3D G3DSA:1.10.287.1060 9 101 7.5E-5 T 12-10-2018 UA74_26435 3674e8b082569c018a27c95002c2bbf7 122 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 11 85 5.3E-28 T 12-10-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA UA74_26435 3674e8b082569c018a27c95002c2bbf7 122 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 5 82 5.1E-25 T 12-10-2018 IPR014295 Anti-sigma factor UA74_21150 3c7b7cf9ee57854f13fd581c4b76ca9c 78 Gene3D G3DSA:2.30.170.40 2 78 1.4E-25 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21150 3c7b7cf9ee57854f13fd581c4b76ca9c 78 Pfam PF00830 Ribosomal L28 family 4 61 2.1E-22 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_21150 3c7b7cf9ee57854f13fd581c4b76ca9c 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 1.6E-24 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21150 3c7b7cf9ee57854f13fd581c4b76ca9c 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 19.259 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_21150 3c7b7cf9ee57854f13fd581c4b76ca9c 78 SUPERFAMILY SSF143800 2 75 2.94E-25 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UA74_01185 456cf10389ebd451068ccc17a64eb7be 392 SUPERFAMILY SSF52540 27 329 1.11E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01185 456cf10389ebd451068ccc17a64eb7be 392 Pfam PF02374 Anion-transporting ATPase 31 302 2.7E-23 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 UA74_01185 456cf10389ebd451068ccc17a64eb7be 392 Gene3D G3DSA:3.40.50.300 18 391 1.4E-78 T 12-10-2018 UA74_11810 c7f4f3ffbff2731ce43c5d56cf0eabc5 501 Gene3D G3DSA:3.20.20.80 9 492 1.9E-157 T 12-10-2018 UA74_11810 c7f4f3ffbff2731ce43c5d56cf0eabc5 501 SUPERFAMILY SSF51445 15 489 3.32E-144 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily UA74_11810 c7f4f3ffbff2731ce43c5d56cf0eabc5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 298 312 2.3E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_11810 c7f4f3ffbff2731ce43c5d56cf0eabc5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 2.3E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_11810 c7f4f3ffbff2731ce43c5d56cf0eabc5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 452 2.3E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_11810 c7f4f3ffbff2731ce43c5d56cf0eabc5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 459 471 2.3E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_11810 c7f4f3ffbff2731ce43c5d56cf0eabc5 501 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 425 2.3E-21 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_11810 c7f4f3ffbff2731ce43c5d56cf0eabc5 501 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 20 34 - T 12-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UA74_11810 c7f4f3ffbff2731ce43c5d56cf0eabc5 501 Pfam PF00232 Glycosyl hydrolase family 1 15 488 9.7E-136 T 12-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UA74_00220 4f6ceb11ca01f17f2e730bb426f0d273 304 Pfam PF01636 Phosphotransferase enzyme family 46 243 1.3E-18 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_00220 4f6ceb11ca01f17f2e730bb426f0d273 304 Gene3D G3DSA:1.10.510.10 169 249 5.0E-9 T 12-10-2018 UA74_00220 4f6ceb11ca01f17f2e730bb426f0d273 304 SUPERFAMILY SSF56112 22 271 3.79E-32 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_20535 bacfb3034b4e4d022c87497aa6dd58ab 377 Gene3D G3DSA:3.20.20.190 65 377 3.9E-117 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_20535 bacfb3034b4e4d022c87497aa6dd58ab 377 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 139 232 3.8E-8 T 12-10-2018 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent UA74_20535 bacfb3034b4e4d022c87497aa6dd58ab 377 SUPERFAMILY SSF51695 71 258 6.8E-9 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_07910 2d2dbda81da93523f8d86ff4a470234e 209 Pfam PF12079 Protein of unknown function (DUF3558) 17 204 5.9E-25 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_18420 5f6b906df8d70c61e621392182860f22 375 SUPERFAMILY SSF53335 74 202 1.69E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_18420 5f6b906df8d70c61e621392182860f22 375 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 72 199 1.4E-30 T 12-10-2018 UA74_19160 83cb362910a4571e9ab9ad8e48f334c4 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 3 92 4.8E-21 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like UA74_29045 178fef3b3a2e860063c44309eed283ec 304 SUPERFAMILY SSF103481 191 294 4.05E-11 T 12-10-2018 UA74_29045 178fef3b3a2e860063c44309eed283ec 304 Pfam PF00892 EamA-like transporter family 14 144 2.8E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_29045 178fef3b3a2e860063c44309eed283ec 304 Pfam PF00892 EamA-like transporter family 159 288 5.2E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_29045 178fef3b3a2e860063c44309eed283ec 304 SUPERFAMILY SSF103481 48 147 8.89E-9 T 12-10-2018 UA74_22355 8deae861a4d7651987ea3f1034883d25 423 Gene3D G3DSA:3.30.1870.10 69 142 1.5E-53 T 12-10-2018 UA74_22355 8deae861a4d7651987ea3f1034883d25 423 Pfam PF05139 Erythromycin esterase 67 409 1.1E-37 T 12-10-2018 IPR007815 Erythromycin esterase GO:0046677 UA74_22355 8deae861a4d7651987ea3f1034883d25 423 SUPERFAMILY SSF159501 4 417 1.15E-63 T 12-10-2018 UA74_22355 8deae861a4d7651987ea3f1034883d25 423 Gene3D G3DSA:3.40.1660.10 10 387 1.5E-53 T 12-10-2018 UA74_22355 8deae861a4d7651987ea3f1034883d25 423 Gene3D G3DSA:1.20.1440.30 143 282 1.5E-53 T 12-10-2018 UA74_17935 181688964cf4c8e1fdf6e0e8d169ece5 429 Pfam PF04143 Sulphur transport 81 409 1.0E-62 T 12-10-2018 IPR007272 Sulphur transport domain UA74_16310 4fa7c445db0d2b60b0b2b90e1e3090ac 237 Pfam PF07508 Recombinase 27 136 3.7E-16 T 12-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 UA74_16310 4fa7c445db0d2b60b0b2b90e1e3090ac 237 Gene3D G3DSA:1.10.10.2600 14 111 5.1E-6 T 12-10-2018 IPR038109 DNA-binding recombinase domain superfamily UA74_03895 41cbd63768b75f4936a1398b85423f41 309 SUPERFAMILY SSF161098 41 305 6.8E-72 T 12-10-2018 IPR035906 MetI-like superfamily UA74_03895 41cbd63768b75f4936a1398b85423f41 309 Gene3D G3DSA:1.10.3720.10 31 299 1.4E-66 T 12-10-2018 IPR035906 MetI-like superfamily UA74_03895 41cbd63768b75f4936a1398b85423f41 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 300 7.0E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_01620 07dace2440e7bc68ffb2ac9e56e34c79 290 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 255 276 8.3E-7 T 12-10-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 UA74_25015 68df42cbb2e97a448b1cb2222e74fb3a 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 109 119 9.0E-6 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UA74_25015 68df42cbb2e97a448b1cb2222e74fb3a 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 256 268 9.0E-6 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UA74_25015 68df42cbb2e97a448b1cb2222e74fb3a 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 269 282 9.0E-6 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UA74_25015 68df42cbb2e97a448b1cb2222e74fb3a 327 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 203 209 9.0E-6 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UA74_25015 68df42cbb2e97a448b1cb2222e74fb3a 327 Pfam PF00248 Aldo/keto reductase family 15 312 7.1E-76 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_25015 68df42cbb2e97a448b1cb2222e74fb3a 327 SUPERFAMILY SSF51430 1 313 4.19E-97 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_25015 68df42cbb2e97a448b1cb2222e74fb3a 327 Gene3D G3DSA:3.20.20.100 1 321 1.4E-113 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_10685 bead94f6c3a20938515837898cafc71e 131 SUPERFAMILY SSF159234 13 129 1.14E-20 T 12-10-2018 IPR035930 FomD-like superfamily UA74_10685 bead94f6c3a20938515837898cafc71e 131 Gene3D G3DSA:2.40.380.10 1 124 1.8E-27 T 12-10-2018 IPR035930 FomD-like superfamily UA74_00255 df7395d3f20806c05549ea2783f09231 400 SMART SM00382 50 246 3.1E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_00255 df7395d3f20806c05549ea2783f09231 400 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_00255 df7395d3f20806c05549ea2783f09231 400 Pfam PF00005 ABC transporter 42 187 7.1E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_00255 df7395d3f20806c05549ea2783f09231 400 Gene3D G3DSA:3.40.50.300 23 305 3.1E-74 T 12-10-2018 UA74_00255 df7395d3f20806c05549ea2783f09231 400 SUPERFAMILY SSF54631 273 387 1.52E-5 T 12-10-2018 UA74_00255 df7395d3f20806c05549ea2783f09231 400 SUPERFAMILY SSF52540 24 263 4.62E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_22280 a1f9c492a01577fe23137fe8e2caf963 317 Gene3D G3DSA:1.10.3720.10 72 311 3.2E-70 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22280 a1f9c492a01577fe23137fe8e2caf963 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 304 5.6E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_22280 a1f9c492a01577fe23137fe8e2caf963 317 SUPERFAMILY SSF161098 76 303 2.22E-62 T 12-10-2018 IPR035906 MetI-like superfamily UA74_30060 e88262b3ee8b14b66dca701c81dacab0 317 Pfam PF00106 short chain dehydrogenase 31 225 9.5E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_30060 e88262b3ee8b14b66dca701c81dacab0 317 SUPERFAMILY SSF51735 27 277 4.39E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_30060 e88262b3ee8b14b66dca701c81dacab0 317 Gene3D G3DSA:3.40.50.720 23 315 7.4E-72 T 12-10-2018 UA74_30060 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 31 48 5.0E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_30060 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 221 5.0E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_30060 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 5.0E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_30060 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 5.0E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_30060 e88262b3ee8b14b66dca701c81dacab0 317 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 101 112 5.0E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UA74_28280 26bda330724643f5285ff987f562c7ef 339 Pfam PF00691 OmpA family 252 317 3.1E-5 T 12-10-2018 IPR006665 OmpA-like domain UA74_28280 26bda330724643f5285ff987f562c7ef 339 SUPERFAMILY SSF103088 243 320 1.12E-7 T 12-10-2018 IPR036737 OmpA-like domain superfamily UA74_28280 26bda330724643f5285ff987f562c7ef 339 Gene3D G3DSA:3.30.1330.60 227 326 2.0E-5 T 12-10-2018 IPR036737 OmpA-like domain superfamily UA74_28280 26bda330724643f5285ff987f562c7ef 339 Gene3D G3DSA:3.40.1520.20 107 219 1.6E-5 T 12-10-2018 UA74_16820 45c13c4e23e20f8d4346ecb0b3e2e6a4 314 SUPERFAMILY SSF53474 25 288 5.77E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_16820 45c13c4e23e20f8d4346ecb0b3e2e6a4 314 Gene3D G3DSA:3.40.50.1820 12 313 3.8E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24370 5463f280befb5c61d655a039892ef6e0 218 Pfam PF02698 DUF218 domain 52 198 7.5E-24 T 12-10-2018 IPR003848 Domain of unknown function DUF218 UA74_25475 fd5c8092a34b277c0d8bccd33ed57721 346 Pfam PF05239 PRC-barrel domain 8 76 2.6E-8 T 12-10-2018 IPR027275 PRC-barrel domain UA74_25475 fd5c8092a34b277c0d8bccd33ed57721 346 Pfam PF09557 Domain of unknown function (DUF2382) 215 326 5.7E-26 T 12-10-2018 IPR019060 Domain of unknown function DUF2382 UA74_25475 fd5c8092a34b277c0d8bccd33ed57721 346 SUPERFAMILY SSF50346 7 110 9.81E-20 T 12-10-2018 IPR011033 PRC-barrel-like superfamily UA74_25475 fd5c8092a34b277c0d8bccd33ed57721 346 Gene3D G3DSA:3.90.50.10 4 112 2.8E-8 T 12-10-2018 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 UA74_01925 0602342893eac828e5364e41ffdb41ff 452 Gene3D G3DSA:3.50.50.60 1 178 1.4E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_01925 0602342893eac828e5364e41ffdb41ff 452 Gene3D G3DSA:3.50.50.60 243 414 5.6E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_01925 0602342893eac828e5364e41ffdb41ff 452 Pfam PF01266 FAD dependent oxidoreductase 1 411 2.2E-59 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UA74_01925 0602342893eac828e5364e41ffdb41ff 452 SUPERFAMILY SSF51971 1 416 1.65E-34 T 12-10-2018 UA74_01925 0602342893eac828e5364e41ffdb41ff 452 Gene3D G3DSA:3.30.9.10 285 378 5.6E-29 T 12-10-2018 UA74_01925 0602342893eac828e5364e41ffdb41ff 452 SUPERFAMILY SSF54373 281 374 9.55E-17 T 12-10-2018 UA74_01925 0602342893eac828e5364e41ffdb41ff 452 Gene3D G3DSA:3.30.9.10 84 141 1.4E-32 T 12-10-2018 UA74_04610 22a45e3028eb7fd0e3cd4094a2afc019 318 Gene3D G3DSA:3.20.20.60 2 313 7.3E-93 T 12-10-2018 UA74_04610 22a45e3028eb7fd0e3cd4094a2afc019 318 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 240 6.4E-42 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 UA74_04610 22a45e3028eb7fd0e3cd4094a2afc019 318 SUPERFAMILY SSF51621 5 251 3.01E-65 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UA74_04610 22a45e3028eb7fd0e3cd4094a2afc019 318 PIRSF PIRSF015582 2 313 9.5E-86 T 12-10-2018 IPR011206 Citrate lyase beta subunit-like UA74_09265 cef57d81d8ade1480b32c0117faaad57 443 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 413 8.8E-91 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_09265 cef57d81d8ade1480b32c0117faaad57 443 Pfam PF01554 MatE 26 186 6.1E-27 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_09265 cef57d81d8ade1480b32c0117faaad57 443 Pfam PF01554 MatE 244 395 9.6E-11 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_09265 cef57d81d8ade1480b32c0117faaad57 443 PIRSF PIRSF006603 11 443 2.3E-50 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_30055 a394c524239c8296e0b58555d3e27136 348 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 2.3E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_30055 a394c524239c8296e0b58555d3e27136 348 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 2.3E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_30055 a394c524239c8296e0b58555d3e27136 348 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 2.3E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_30055 a394c524239c8296e0b58555d3e27136 348 SUPERFAMILY SSF46955 10 113 4.76E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily UA74_30055 a394c524239c8296e0b58555d3e27136 348 Pfam PF13411 MerR HTH family regulatory protein 10 78 2.0E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_30055 a394c524239c8296e0b58555d3e27136 348 Gene3D G3DSA:1.10.1660.10 3 123 3.2E-26 T 12-10-2018 UA74_30055 a394c524239c8296e0b58555d3e27136 348 SMART SM00422 10 79 1.5E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UA74_00985 d647b10549dee3b9ce9821b138446253 450 PRINTS PR01228 Eggshell protein signature 332 342 5.8E-5 T 12-10-2018 UA74_00985 d647b10549dee3b9ce9821b138446253 450 PRINTS PR01228 Eggshell protein signature 224 235 5.8E-5 T 12-10-2018 UA74_00985 d647b10549dee3b9ce9821b138446253 450 PRINTS PR01228 Eggshell protein signature 366 384 5.8E-5 T 12-10-2018 UA74_00985 d647b10549dee3b9ce9821b138446253 450 PRINTS PR01228 Eggshell protein signature 304 319 5.8E-5 T 12-10-2018 UA74_00985 d647b10549dee3b9ce9821b138446253 450 SUPERFAMILY SSF140459 18 173 2.62E-6 T 12-10-2018 UA74_26690 75842381499121d97bd0537f37a980a6 533 Gene3D G3DSA:1.10.260.150 84 401 2.2E-63 T 12-10-2018 UA74_26690 75842381499121d97bd0537f37a980a6 533 Gene3D G3DSA:3.30.70.2390 406 487 2.0E-6 T 12-10-2018 UA74_26690 75842381499121d97bd0537f37a980a6 533 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 408 491 1.9E-15 T 12-10-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain UA74_26690 75842381499121d97bd0537f37a980a6 533 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 134 302 2.3E-37 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_26690 75842381499121d97bd0537f37a980a6 533 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 134 303 8.5E-33 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UA74_28780 cced8dcb1ec1b29bc8cc97ee01153bf7 666 Pfam PF13440 Polysaccharide biosynthesis protein 213 457 5.6E-47 T 12-10-2018 UA74_09575 e811b21074fa09f93d4c29fd96f6be70 263 Gene3D G3DSA:3.40.50.150 1 253 5.7E-46 T 12-10-2018 UA74_09575 e811b21074fa09f93d4c29fd96f6be70 263 Pfam PF13489 Methyltransferase domain 13 196 1.4E-18 T 12-10-2018 UA74_09575 e811b21074fa09f93d4c29fd96f6be70 263 SUPERFAMILY SSF53335 23 203 1.27E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_07305 1a04521f409a71b0f7eef030357643a1 129 SUPERFAMILY SSF55811 10 108 8.53E-17 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_07305 1a04521f409a71b0f7eef030357643a1 129 Gene3D G3DSA:3.90.79.10 2 126 2.4E-18 T 12-10-2018 UA74_07305 1a04521f409a71b0f7eef030357643a1 129 Pfam PF00293 NUDIX domain 14 107 6.2E-9 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_15825 0dd300ac620b62ad77343affdab1dca2 165 Pfam PF01930 Domain of unknown function DUF83 9 164 4.8E-35 T 12-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 UA74_23250 6ce91dde07fe9236d4112a3513f3a4dc 305 Gene3D G3DSA:2.130.10.10 103 302 4.5E-73 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_23250 6ce91dde07fe9236d4112a3513f3a4dc 305 Hamap MF_01282 Virginiamycin B lyase [vgb]. 14 301 43.436 T 12-10-2018 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 UA74_23250 6ce91dde07fe9236d4112a3513f3a4dc 305 SUPERFAMILY SSF63829 13 223 4.38E-28 T 12-10-2018 UA74_23250 6ce91dde07fe9236d4112a3513f3a4dc 305 SUPERFAMILY SSF63829 187 301 2.13E-12 T 12-10-2018 UA74_23250 6ce91dde07fe9236d4112a3513f3a4dc 305 PIRSF PIRSF026412 3 302 5.5E-100 T 12-10-2018 IPR011217 Streptogramin lyase GO:0000287|GO:0016835|GO:0017001|GO:0046677 UA74_01035 90663280308c2bd788e4123a1d604b8a 223 SUPERFAMILY SSF52540 41 204 2.04E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_01035 90663280308c2bd788e4123a1d604b8a 223 Gene3D G3DSA:3.40.50.300 24 208 1.2E-21 T 12-10-2018 UA74_14630 c99490eeb8efeffc479a4ce38dfd730e 185 SUPERFAMILY SSF160904 7 178 1.26E-31 T 12-10-2018 UA74_14630 c99490eeb8efeffc479a4ce38dfd730e 185 Gene3D G3DSA:1.10.3300.10 17 180 6.5E-21 T 12-10-2018 IPR023286 ABATE domain superfamily UA74_14630 c99490eeb8efeffc479a4ce38dfd730e 185 Pfam PF11706 CGNR zinc finger 136 179 3.0E-17 T 12-10-2018 IPR021005 Zinc finger, CGNR UA74_12440 2d093a38e5506da05b5ad4c05d39f91c 668 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 91 382 1.5E-35 T 12-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 UA74_12440 2d093a38e5506da05b5ad4c05d39f91c 668 SUPERFAMILY SSF55486 265 339 5.13E-6 T 12-10-2018 UA74_12940 e235196239b438c00eb1ee647c81cc52 212 Pfam PF14230 Domain of unknown function (DUF4333) 127 204 1.3E-24 T 12-10-2018 IPR025637 Domain of unknown function DUF4333 UA74_18225 e588e2cadf055ae1fb184873c22c822b 398 Gene3D G3DSA:1.10.260.40 5 92 1.7E-11 T 12-10-2018 UA74_18225 e588e2cadf055ae1fb184873c22c822b 398 SMART SM00530 11 66 9.8E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_18225 e588e2cadf055ae1fb184873c22c822b 398 SUPERFAMILY SSF47413 3 69 6.48E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_08200 b61151a4e33899c0aec26b56fee56db6 469 Gene3D G3DSA:1.25.40.10 268 412 7.3E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_08200 b61151a4e33899c0aec26b56fee56db6 469 SUPERFAMILY SSF48452 280 408 1.98E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_13000 dd5ccdf99be52417af23ada9dcd2ca9a 191 Pfam PF04186 FxsA cytoplasmic membrane protein 3 106 9.0E-25 T 12-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 UA74_04020 5e59e381f9354d14eed26e28d63a2630 159 Pfam PF14155 Domain of unknown function (DUF4307) 27 135 1.8E-31 T 12-10-2018 IPR025443 Protein of unknown function DUF4307 UA74_10900 dbd9510b16a3262185129bf1294c37b7 287 SUPERFAMILY SSF51679 1 285 5.23E-53 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_10900 dbd9510b16a3262185129bf1294c37b7 287 Gene3D G3DSA:3.20.20.30 5 287 1.4E-53 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UA74_10900 dbd9510b16a3262185129bf1294c37b7 287 Pfam PF00296 Luciferase-like monooxygenase 5 261 1.5E-37 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UA74_05465 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 335 347 4.0E-15 T 12-10-2018 UA74_05465 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 434 459 4.0E-15 T 12-10-2018 UA74_05465 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 366 387 4.0E-15 T 12-10-2018 UA74_05465 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 477 489 4.0E-15 T 12-10-2018 UA74_05465 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 387 403 4.0E-15 T 12-10-2018 UA74_05465 361efcb8cae45c15a44bf944637adf53 539 PRINTS PR01217 Proline rich extensin signature 416 433 4.0E-15 T 12-10-2018 UA74_02605 8ea4d00f14bc724eef0ab60d91ee4537 381 Gene3D G3DSA:1.20.120.1200 38 201 2.2E-42 T 12-10-2018 UA74_02605 8ea4d00f14bc724eef0ab60d91ee4537 381 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 50 197 1.1E-33 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UA74_20055 0bfb721ef01a8815946fd19e92351348 91 Gene3D G3DSA:3.30.1310.10 7 91 3.3E-6 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_20055 0bfb721ef01a8815946fd19e92351348 91 SUPERFAMILY SSF82607 19 90 4.19E-5 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UA74_20055 0bfb721ef01a8815946fd19e92351348 91 Pfam PF02575 YbaB/EbfC DNA-binding family 25 90 4.6E-6 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UA74_16150 c471350686649cbaddff6ac07a80fefd 144 Gene3D G3DSA:1.10.10.10 10 131 3.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_16150 c471350686649cbaddff6ac07a80fefd 144 Pfam PF01638 HxlR-like helix-turn-helix 18 117 2.7E-8 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type UA74_16150 c471350686649cbaddff6ac07a80fefd 144 SUPERFAMILY SSF46785 13 119 4.43E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_18895 a3516425a9de0734509b9424ef95e860 158 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 91 1.1E-10 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 UA74_18895 a3516425a9de0734509b9424ef95e860 158 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 14 144 2.7E-34 T 12-10-2018 IPR019920 F420-binding domain, putative UA74_18895 a3516425a9de0734509b9424ef95e860 158 Gene3D G3DSA:2.30.110.10 12 149 6.8E-38 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_18895 a3516425a9de0734509b9424ef95e860 158 SUPERFAMILY SSF50475 14 146 1.53E-31 T 12-10-2018 UA74_29465 cac518467bd67983810025772c4795bb 326 Pfam PF06197 Protein of unknown function (DUF998) 35 228 2.1E-16 T 12-10-2018 IPR009339 Protein of unknown function DUF998 UA74_28980 26e13986b682ca009c2fb2f2e6156b1e 124 Pfam PF02467 Transcription factor WhiB 57 103 4.2E-11 T 12-10-2018 IPR034768 WhiB-like iron-sulfur binding domain UA74_08600 0450a92f6bf5309012d561779486733c 444 Pfam PF03993 Domain of Unknown Function (DUF349) 209 281 3.0E-19 T 12-10-2018 IPR007139 Protein of unknown function DUF349 UA74_08600 0450a92f6bf5309012d561779486733c 444 Pfam PF03993 Domain of Unknown Function (DUF349) 133 205 4.5E-13 T 12-10-2018 IPR007139 Protein of unknown function DUF349 UA74_08600 0450a92f6bf5309012d561779486733c 444 Pfam PF03993 Domain of Unknown Function (DUF349) 287 359 1.2E-20 T 12-10-2018 IPR007139 Protein of unknown function DUF349 UA74_26900 f8c1ada59e148c1b2630ea00ebee4cdd 369 SUPERFAMILY SSF53850 64 361 3.2E-50 T 12-10-2018 UA74_26900 f8c1ada59e148c1b2630ea00ebee4cdd 369 Gene3D G3DSA:3.40.190.10 82 335 5.3E-49 T 12-10-2018 UA74_26900 f8c1ada59e148c1b2630ea00ebee4cdd 369 Gene3D G3DSA:3.40.190.10 163 352 5.3E-49 T 12-10-2018 UA74_26900 f8c1ada59e148c1b2630ea00ebee4cdd 369 Pfam PF13343 Bacterial extracellular solute-binding protein 116 330 3.8E-22 T 12-10-2018 UA74_14835 3f113ec9cf37095e377b682e8b72920d 299 Gene3D G3DSA:3.40.50.720 19 273 9.6E-54 T 12-10-2018 UA74_14835 3f113ec9cf37095e377b682e8b72920d 299 Pfam PF13460 NAD(P)H-binding 22 187 2.0E-15 T 12-10-2018 IPR016040 NAD(P)-binding domain UA74_14835 3f113ec9cf37095e377b682e8b72920d 299 SUPERFAMILY SSF51735 17 288 1.37E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_14835 3f113ec9cf37095e377b682e8b72920d 299 Gene3D G3DSA:3.90.25.10 140 275 9.6E-54 T 12-10-2018 UA74_02815 75c03193d9b4e738ffe02643a0444e85 141 SUPERFAMILY SSF54637 7 131 4.66E-28 T 12-10-2018 IPR029069 HotDog domain superfamily UA74_02815 75c03193d9b4e738ffe02643a0444e85 141 PRINTS PR01483 Fatty acid synthase signature 24 46 6.8E-6 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 UA74_02815 75c03193d9b4e738ffe02643a0444e85 141 PRINTS PR01483 Fatty acid synthase signature 46 67 6.8E-6 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 UA74_02815 75c03193d9b4e738ffe02643a0444e85 141 Pfam PF01575 MaoC like domain 16 121 2.3E-25 T 12-10-2018 IPR002539 MaoC-like dehydratase domain UA74_02815 75c03193d9b4e738ffe02643a0444e85 141 Gene3D G3DSA:3.10.129.10 1 141 1.2E-44 T 12-10-2018 UA74_20515 7abbf66e69647fc67e05229c2c2a9104 273 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 46 170 2.1E-25 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ UA74_14375 3286560d6dfabfd99ad4b327788c87ce 72 Pfam PF11160 Protein of unknown function (DUF2945) 9 68 1.1E-24 T 12-10-2018 IPR021331 Protein of unknown function DUF2945 UA74_26700 24ab991efe24e9ccc0799d80b5d0aab9 260 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 7 251 1.2E-55 T 12-10-2018 IPR017523 Conserved hypothetical protein CHP03089 UA74_26700 24ab991efe24e9ccc0799d80b5d0aab9 260 Gene3D G3DSA:3.40.50.12780 18 257 5.2E-6 T 12-10-2018 UA74_26700 24ab991efe24e9ccc0799d80b5d0aab9 260 SUPERFAMILY SSF56801 8 254 1.96E-16 T 12-10-2018 UA74_08550 998b7ec26c53c900b30847a0501c7501 211 Gene3D G3DSA:3.20.20.70 2 210 2.4E-70 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_08550 998b7ec26c53c900b30847a0501c7501 211 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 12-10-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_08550 998b7ec26c53c900b30847a0501c7501 211 Pfam PF01081 KDPG and KHG aldolase 11 201 4.2E-67 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_08550 998b7ec26c53c900b30847a0501c7501 211 SUPERFAMILY SSF51569 6 208 1.7E-64 T 12-10-2018 UA74_08550 998b7ec26c53c900b30847a0501c7501 211 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 12-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_08550 998b7ec26c53c900b30847a0501c7501 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 207 3.7E-75 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UA74_00600 90675e93c2d337e5348a51a38cd7d273 438 Pfam PF13845 Septum formation 82 128 5.2E-9 T 12-10-2018 IPR026004 Septum formation-related domain UA74_00600 90675e93c2d337e5348a51a38cd7d273 438 Pfam PF13845 Septum formation 161 340 1.8E-51 T 12-10-2018 IPR026004 Septum formation-related domain UA74_23620 a36cfa1e0e88ddc0e43b94e68856ba20 275 Gene3D G3DSA:3.40.50.1110 35 262 8.7E-76 T 12-10-2018 IPR036514 SGNH hydrolase superfamily UA74_23620 a36cfa1e0e88ddc0e43b94e68856ba20 275 SUPERFAMILY SSF52266 34 254 2.83E-63 T 12-10-2018 UA74_23620 a36cfa1e0e88ddc0e43b94e68856ba20 275 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 39 254 2.7E-23 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain UA74_23260 b25ebe8ad1088705f2ade3330ceaadd6 224 Gene3D G3DSA:3.30.70.100 10 117 1.1E-17 T 12-10-2018 UA74_23260 b25ebe8ad1088705f2ade3330ceaadd6 224 Gene3D G3DSA:3.30.70.100 118 219 1.5E-12 T 12-10-2018 UA74_08490 4a5650e47333bb10dda5e0d2326611c8 221 Pfam PF02080 TrkA-C domain 147 208 8.8E-8 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UA74_08490 4a5650e47333bb10dda5e0d2326611c8 221 Gene3D G3DSA:3.30.70.1450 142 213 3.7E-7 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UA74_08490 4a5650e47333bb10dda5e0d2326611c8 221 SUPERFAMILY SSF116726 130 208 2.49E-6 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UA74_08490 4a5650e47333bb10dda5e0d2326611c8 221 Gene3D G3DSA:3.40.50.720 1 131 6.3E-29 T 12-10-2018 UA74_08490 4a5650e47333bb10dda5e0d2326611c8 221 Pfam PF02254 TrkA-N domain 3 117 1.3E-22 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UA74_08490 4a5650e47333bb10dda5e0d2326611c8 221 SUPERFAMILY SSF51735 2 140 7.48E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_12615 d6df5a0a97768f0f02349cbfee0d67f6 186 Gene3D G3DSA:3.40.50.1820 1 93 1.4E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_18020 d270ea4fd4a97c9a5c74cdf5f7a3b399 294 SUPERFAMILY SSF50934 132 258 9.94E-15 T 12-10-2018 IPR036813 Tachylectin 2 superfamily UA74_18020 d270ea4fd4a97c9a5c74cdf5f7a3b399 294 Pfam PF14517 Tachylectin 53 255 7.8E-21 T 12-10-2018 IPR023294 Tachylectin 2 UA74_18020 d270ea4fd4a97c9a5c74cdf5f7a3b399 294 Gene3D G3DSA:2.20.25.650 177 281 3.9E-13 T 12-10-2018 UA74_18020 d270ea4fd4a97c9a5c74cdf5f7a3b399 294 Gene3D G3DSA:2.115.10.10 39 173 3.5E-14 T 12-10-2018 UA74_19090 fb34e19fdd1eb0d282154c494bf96038 98 SUPERFAMILY SSF140453 4 94 3.66E-6 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_19090 fb34e19fdd1eb0d282154c494bf96038 98 Gene3D G3DSA:1.10.287.1060 1 93 1.2E-6 T 12-10-2018 UA74_17070 b39997b50c92dd77dbaba7f063ef6368 245 Gene3D G3DSA:3.90.79.10 13 152 2.8E-39 T 12-10-2018 UA74_17070 b39997b50c92dd77dbaba7f063ef6368 245 Pfam PF00293 NUDIX domain 18 142 2.0E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_17070 b39997b50c92dd77dbaba7f063ef6368 245 SUPERFAMILY SSF46785 158 229 9.11E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_17070 b39997b50c92dd77dbaba7f063ef6368 245 Gene3D G3DSA:1.10.10.10 153 226 1.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17070 b39997b50c92dd77dbaba7f063ef6368 245 SUPERFAMILY SSF55811 5 154 9.07E-28 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_15475 28ec2bb91a101919470c25e9a76dac7d 189 SUPERFAMILY SSF53597 1 185 1.22E-34 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_15475 28ec2bb91a101919470c25e9a76dac7d 189 Gene3D G3DSA:3.40.430.10 2 183 2.8E-47 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UA74_15475 28ec2bb91a101919470c25e9a76dac7d 189 Pfam PF01872 RibD C-terminal domain 4 180 7.5E-25 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UA74_23095 8c173f514016536694799160b6f2fb8c 542 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 4 488 2.6E-96 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 UA74_23095 8c173f514016536694799160b6f2fb8c 542 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 4 339 2.4E-47 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 UA74_08810 f45708b7ed63022904cacb51ea0ab935 379 Gene3D G3DSA:3.20.20.140 51 327 3.4E-50 T 12-10-2018 UA74_08810 f45708b7ed63022904cacb51ea0ab935 379 Pfam PF01979 Amidohydrolase family 167 356 4.5E-10 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_08810 f45708b7ed63022904cacb51ea0ab935 379 Gene3D G3DSA:2.30.40.10 41 361 3.4E-50 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_08810 f45708b7ed63022904cacb51ea0ab935 379 SUPERFAMILY SSF51556 49 328 7.66E-60 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_07695 c54c63e0a08fa67eaf618668d1bd03b7 137 Pfam PF13471 Transglutaminase-like superfamily 23 132 4.2E-26 T 12-10-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal UA74_10320 de7898b2591a1a816f850725732e91bb 206 Pfam PF01810 LysE type translocator 15 201 1.7E-24 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 UA74_04680 1ec7db657e16ac7b7adbc7bd1d8e71db 289 SMART SM00481 3 67 9.3E-17 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal UA74_04680 1ec7db657e16ac7b7adbc7bd1d8e71db 289 SUPERFAMILY SSF89550 2 271 5.89E-40 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UA74_04680 1ec7db657e16ac7b7adbc7bd1d8e71db 289 Gene3D G3DSA:3.20.20.140 3 253 8.3E-71 T 12-10-2018 UA74_04680 1ec7db657e16ac7b7adbc7bd1d8e71db 289 Gene3D G3DSA:1.10.150.650 100 172 8.3E-71 T 12-10-2018 UA74_04680 1ec7db657e16ac7b7adbc7bd1d8e71db 289 Pfam PF02811 PHP domain 4 81 8.0E-7 T 12-10-2018 IPR004013 PHP domain GO:0003824 UA74_23460 ebd8d6b0e3cfd830900542f408339e92 239 Pfam PF04343 Protein of unknown function, DUF488 78 197 3.2E-25 T 12-10-2018 IPR007438 Protein of unknown function DUF488 UA74_23460 ebd8d6b0e3cfd830900542f408339e92 239 PIRSF PIRSF024492 61 238 2.9E-42 T 12-10-2018 IPR014519 Uncharacterised conserved protein UCP024492 UA74_27685 b37599f45f0c9b52a9f34a0f976eb930 135 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 4 132 2.2E-50 T 12-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_27685 b37599f45f0c9b52a9f34a0f976eb930 135 SUPERFAMILY SSF52242 3 131 1.44E-49 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_27685 b37599f45f0c9b52a9f34a0f976eb930 135 Pfam PF02310 B12 binding domain 5 115 3.1E-23 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UA74_27685 b37599f45f0c9b52a9f34a0f976eb930 135 Gene3D G3DSA:3.40.50.280 2 134 1.0E-58 T 12-10-2018 UA74_12910 156b1914761cb7461fcfa82bcd110f1a 316 Pfam PF13280 WYL domain 138 309 1.0E-26 T 12-10-2018 IPR026881 WYL domain UA74_04270 70fee588caca1ce341cda7837e231ece 99 SUPERFAMILY SSF55248 1 94 1.44E-27 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 UA74_04270 70fee588caca1ce341cda7837e231ece 99 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 91 4.0E-26 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 UA74_04270 70fee588caca1ce341cda7837e231ece 99 Gene3D G3DSA:3.30.1360.20 4 99 1.8E-27 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 UA74_04270 70fee588caca1ce341cda7837e231ece 99 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 2 93 20.448 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 UA74_00785 0b7659b5b01ef7f48014dce40b411e73 74 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 7 65 1.6E-12 T 12-10-2018 IPR018691 Protein of unknown function DUF2188 UA74_10605 79c3b83c0200e320da1368ba98787f6f 402 Pfam PF13458 Periplasmic binding protein 66 393 4.6E-43 T 12-10-2018 IPR028081 Leucine-binding protein domain UA74_10605 79c3b83c0200e320da1368ba98787f6f 402 SUPERFAMILY SSF53822 66 396 2.76E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_10605 79c3b83c0200e320da1368ba98787f6f 402 Gene3D G3DSA:3.40.50.2300 181 306 2.3E-74 T 12-10-2018 UA74_10605 79c3b83c0200e320da1368ba98787f6f 402 Gene3D G3DSA:3.40.50.2300 66 376 2.3E-74 T 12-10-2018 UA74_02440 f2d279a7510f0c94276511fabf0061ee 295 Gene3D G3DSA:1.10.287.1060 56 145 3.7E-6 T 12-10-2018 UA74_02440 f2d279a7510f0c94276511fabf0061ee 295 SUPERFAMILY SSF140453 58 108 6.15E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_20840 cf66b5836fa96233e77f0307381b72e8 241 Pfam PF14065 Protein of unknown function (DUF4255) 4 179 4.0E-43 T 12-10-2018 IPR025351 Protein of unknown function DUF4255 UA74_28760 5742de6509c5602ee9eeb14dfa3571b2 449 Gene3D G3DSA:3.90.1150.10 18 413 6.5E-112 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_28760 5742de6509c5602ee9eeb14dfa3571b2 449 SUPERFAMILY SSF53383 11 417 3.86E-77 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_28760 5742de6509c5602ee9eeb14dfa3571b2 449 Gene3D G3DSA:3.40.640.10 80 320 6.5E-112 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_28760 5742de6509c5602ee9eeb14dfa3571b2 449 Pfam PF00202 Aminotransferase class-III 45 390 1.7E-35 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UA74_22815 8accf49ff85bb31d83266e31bcae1c6a 287 SUPERFAMILY SSF47413 12 76 4.93E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_22815 8accf49ff85bb31d83266e31bcae1c6a 287 Gene3D G3DSA:1.10.260.40 12 79 8.7E-7 T 12-10-2018 UA74_22815 8accf49ff85bb31d83266e31bcae1c6a 287 Pfam PF13560 Helix-turn-helix domain 20 80 1.3E-10 T 12-10-2018 UA74_04110 bc5ed67bcf110becf56f4cc9494e7bd2 335 Pfam PF00892 EamA-like transporter family 96 178 5.8E-9 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_04110 bc5ed67bcf110becf56f4cc9494e7bd2 335 Pfam PF00892 EamA-like transporter family 187 320 4.5E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_04110 bc5ed67bcf110becf56f4cc9494e7bd2 335 SUPERFAMILY SSF103481 233 321 2.75E-7 T 12-10-2018 UA74_04110 bc5ed67bcf110becf56f4cc9494e7bd2 335 SUPERFAMILY SSF103481 54 182 7.59E-12 T 12-10-2018 UA74_23905 e038051979bcf8131f2500665f19eb95 106 Gene3D G3DSA:1.10.287.1060 1 99 2.7E-6 T 12-10-2018 UA74_23905 e038051979bcf8131f2500665f19eb95 106 SUPERFAMILY SSF140453 4 99 6.15E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_14040 de418336ac87b26fa238da95ba797417 669 SUPERFAMILY SSF53300 482 652 3.12E-16 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_14040 de418336ac87b26fa238da95ba797417 669 Gene3D G3DSA:3.40.50.410 476 657 2.4E-16 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_14040 de418336ac87b26fa238da95ba797417 669 SMART SM00327 480 662 7.3E-12 T 12-10-2018 IPR002035 von Willebrand factor, type A UA74_24045 a1f1a99b87de6fd8bdf072d994328127 1569 Pfam PF13087 AAA domain 1124 1307 7.0E-15 T 12-10-2018 UA74_24045 a1f1a99b87de6fd8bdf072d994328127 1569 Gene3D G3DSA:3.40.960.10 1352 1452 3.3E-14 T 12-10-2018 UA74_24045 a1f1a99b87de6fd8bdf072d994328127 1569 Gene3D G3DSA:3.40.50.300 1143 1341 1.6E-25 T 12-10-2018 UA74_24045 a1f1a99b87de6fd8bdf072d994328127 1569 Pfam PF13086 AAA domain 363 426 2.0E-8 T 12-10-2018 UA74_24045 a1f1a99b87de6fd8bdf072d994328127 1569 Gene3D G3DSA:3.40.50.300 827 1112 3.9E-8 T 12-10-2018 UA74_24045 a1f1a99b87de6fd8bdf072d994328127 1569 Gene3D G3DSA:3.40.50.300 308 510 8.9E-19 T 12-10-2018 UA74_24045 a1f1a99b87de6fd8bdf072d994328127 1569 SUPERFAMILY SSF52540 360 1312 3.54E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24045 a1f1a99b87de6fd8bdf072d994328127 1569 SUPERFAMILY SSF52980 1347 1451 5.9E-8 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_26005 492e714f4517d432eb5ef95e4f47de2b 400 SUPERFAMILY SSF63829 89 398 2.09E-12 T 12-10-2018 UA74_26005 492e714f4517d432eb5ef95e4f47de2b 400 Pfam PF07995 Glucose / Sorbosone dehydrogenase 101 297 9.4E-20 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase UA74_26005 492e714f4517d432eb5ef95e4f47de2b 400 Gene3D G3DSA:2.120.10.30 67 390 9.2E-49 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_22505 21c0f8591c5badc4183c93285717e23c 274 Pfam PF07920 Protein of unknown function (DUF1684) 124 264 3.0E-35 T 12-10-2018 IPR012467 Protein of unknown function DUF1684 UA74_12530 846543aa0e46c7250c9b1fb70ae4dc86 111 Gene3D G3DSA:2.102.10.10 1 108 1.5E-29 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_12530 846543aa0e46c7250c9b1fb70ae4dc86 111 Pfam PF00355 Rieske [2Fe-2S] domain 4 93 5.8E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UA74_12530 846543aa0e46c7250c9b1fb70ae4dc86 111 SUPERFAMILY SSF50022 1 105 4.84E-27 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UA74_15285 718855060ffef4fc229a8c20637039a8 125 SUPERFAMILY SSF54909 14 114 1.07E-20 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_15285 718855060ffef4fc229a8c20637039a8 125 Pfam PF03795 YCII-related domain 1 113 1.0E-10 T 12-10-2018 IPR005545 YCII-related UA74_15285 718855060ffef4fc229a8c20637039a8 125 Gene3D G3DSA:3.30.70.1060 1 117 1.3E-32 T 12-10-2018 UA74_20790 d8549fa1d1f777ae90f13a8c736dfa45 503 Gene3D G3DSA:3.40.50.11780 220 350 7.9E-10 T 12-10-2018 UA74_20790 d8549fa1d1f777ae90f13a8c736dfa45 503 Pfam PF17482 Phage tail sheath C-terminal domain 386 492 2.3E-20 T 12-10-2018 IPR020287 Tail sheath protein, C-terminal domain UA74_20790 d8549fa1d1f777ae90f13a8c736dfa45 503 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 225 385 2.9E-34 T 12-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain UA74_11555 a94f17414b5e6ec7b7fb4a61fc0e16f4 258 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 1 249 6.0E-17 T 12-10-2018 UA74_07465 9ed8c1aec270326d32246fdedc19459c 305 SUPERFAMILY SSF53474 57 299 2.79E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07465 9ed8c1aec270326d32246fdedc19459c 305 Gene3D G3DSA:3.40.50.1820 25 301 1.5E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_07465 9ed8c1aec270326d32246fdedc19459c 305 Pfam PF00561 alpha/beta hydrolase fold 79 189 9.5E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_10420 551f097604d3102780b7be4b45a1631b 187 Gene3D G3DSA:3.40.50.10490 1 185 2.9E-61 T 12-10-2018 UA74_10420 551f097604d3102780b7be4b45a1631b 187 SUPERFAMILY SSF53697 2 184 4.65E-45 T 12-10-2018 UA74_10420 551f097604d3102780b7be4b45a1631b 187 Pfam PF13580 SIS domain 19 140 1.9E-25 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UA74_18480 4514b1ed44397b51e9ee90bccb3368f6 62 Pfam PF04149 Domain of unknown function (DUF397) 7 57 8.4E-19 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_04870 6bd1316357e1340161c50fadac963b52 376 SUPERFAMILY SSF69572 128 344 7.19E-9 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 UA74_04870 6bd1316357e1340161c50fadac963b52 376 Pfam PF00899 ThiF family 127 340 1.3E-7 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 UA74_04870 6bd1316357e1340161c50fadac963b52 376 Gene3D G3DSA:3.40.50.720 170 344 4.3E-22 T 12-10-2018 UA74_01425 43707936c7e581d64393a46e4cd80758 213 SMART SM00943 19 181 5.5E-11 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal UA74_11415 8355091b93de0f3c0eea8dcd3753bbc5 400 Pfam PF13531 Bacterial extracellular solute-binding protein 60 356 3.4E-22 T 12-10-2018 UA74_11415 8355091b93de0f3c0eea8dcd3753bbc5 400 SUPERFAMILY SSF53850 57 356 3.98E-6 T 12-10-2018 UA74_20820 f58fedbe438d5ab6ddffe8c956a22189 204 Pfam PF01810 LysE type translocator 15 202 4.4E-45 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 UA74_17400 6d87fb5281c15c8d1e092d0800bd1c14 66 SUPERFAMILY SSF54862 2 61 4.41E-14 T 12-10-2018 UA74_17400 6d87fb5281c15c8d1e092d0800bd1c14 66 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 61 3.0E-13 T 12-10-2018 UA74_17400 6d87fb5281c15c8d1e092d0800bd1c14 66 Gene3D G3DSA:3.30.70.20 1 63 1.3E-19 T 12-10-2018 UA74_17400 6d87fb5281c15c8d1e092d0800bd1c14 66 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 2.7E-7 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_17400 6d87fb5281c15c8d1e092d0800bd1c14 66 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.7E-7 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_17400 6d87fb5281c15c8d1e092d0800bd1c14 66 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.7E-7 T 12-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UA74_26875 c320bd5823fb5b4a08dd5c2429ff9e66 130 Gene3D G3DSA:3.10.180.10 1 128 3.5E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_26875 c320bd5823fb5b4a08dd5c2429ff9e66 130 SUPERFAMILY SSF54593 3 127 1.34E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_26875 c320bd5823fb5b4a08dd5c2429ff9e66 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 125 5.0E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_01980 1a7aa36912d3e706c7bfb6385c7f6157 309 SUPERFAMILY SSF161098 65 293 1.31E-52 T 12-10-2018 IPR035906 MetI-like superfamily UA74_01980 1a7aa36912d3e706c7bfb6385c7f6157 309 Gene3D G3DSA:1.10.3720.10 61 305 3.2E-56 T 12-10-2018 IPR035906 MetI-like superfamily UA74_01980 1a7aa36912d3e706c7bfb6385c7f6157 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 297 5.0E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_16045 a7380d371452fc1952c72ab20b02ce65 213 SUPERFAMILY SSF53167 51 179 4.19E-8 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 UA74_23915 bfa5485b1f37b32804cb97176627b679 265 Pfam PF03211 Pectate lyase 44 237 3.5E-73 T 12-10-2018 IPR004898 Pectate lyase PlyH/PlyE-like GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 UA74_23915 bfa5485b1f37b32804cb97176627b679 265 SUPERFAMILY SSF51126 48 220 2.28E-51 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor UA74_23915 bfa5485b1f37b32804cb97176627b679 265 Gene3D G3DSA:2.160.20.10 48 265 8.6E-73 T 12-10-2018 IPR012334 Pectin lyase fold UA74_00710 2c1463f1a8fca9abf5a60438d010c2c0 195 Pfam PF10759 Protein of unknown function (DUF2587) 47 182 9.6E-77 T 12-10-2018 IPR019695 Bacterial proteasome activator GO:0061136 UA74_24640 08fda7561f2615e90751fc5bdb9a6700 259 Pfam PF07398 MDMPI C-terminal domain 152 248 1.2E-8 T 12-10-2018 IPR010872 MDMPI C-terminal UA74_24640 08fda7561f2615e90751fc5bdb9a6700 259 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 33 138 1.5E-9 T 12-10-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 UA74_08410 605fb9274439723f2db27d03cf690528 259 Gene3D G3DSA:3.40.50.300 5 246 2.4E-61 T 12-10-2018 UA74_08410 605fb9274439723f2db27d03cf690528 259 SUPERFAMILY SSF52540 5 234 9.53E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_08410 605fb9274439723f2db27d03cf690528 259 Pfam PF00005 ABC transporter 23 174 8.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_08410 605fb9274439723f2db27d03cf690528 259 SMART SM00382 32 230 3.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_05190 08885d28cf00aead37ff81e0a04eef0e 279 SUPERFAMILY SSF53335 24 226 3.05E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_05190 08885d28cf00aead37ff81e0a04eef0e 279 Pfam PF08241 Methyltransferase domain 53 150 1.1E-17 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UA74_05190 08885d28cf00aead37ff81e0a04eef0e 279 Gene3D G3DSA:3.40.50.150 7 231 9.4E-37 T 12-10-2018 UA74_03005 a7d09a24a5e1e09a76c09ea30bd222ec 191 Gene3D G3DSA:3.30.1440.10 6 186 4.2E-73 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03005 a7d09a24a5e1e09a76c09ea30bd222ec 191 PIRSF PIRSF002161 5 191 5.1E-60 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03005 a7d09a24a5e1e09a76c09ea30bd222ec 191 SUPERFAMILY SSF55282 10 185 2.12E-70 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03005 a7d09a24a5e1e09a76c09ea30bd222ec 191 Pfam PF00673 ribosomal L5P family C-terminus 91 184 7.5E-37 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_03005 a7d09a24a5e1e09a76c09ea30bd222ec 191 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 42.015 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UA74_03005 a7d09a24a5e1e09a76c09ea30bd222ec 191 Pfam PF00281 Ribosomal protein L5 31 87 1.9E-25 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UA74_22200 005c46b8d4e359020953d89c9fa7e9b6 217 SUPERFAMILY SSF53335 3 208 2.43E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_22200 005c46b8d4e359020953d89c9fa7e9b6 217 Gene3D G3DSA:3.40.50.150 6 215 9.0E-37 T 12-10-2018 UA74_22200 005c46b8d4e359020953d89c9fa7e9b6 217 Pfam PF13649 Methyltransferase domain 39 128 2.6E-14 T 12-10-2018 UA74_17335 c92a564b389189b975efb66f81458e14 323 Pfam PF11512 Agrobacterium tumefaciens protein Atu4866 249 321 5.2E-34 T 12-10-2018 IPR020955 Uncharacterised protein family Atu4866 UA74_17335 c92a564b389189b975efb66f81458e14 323 Pfam PF11512 Agrobacterium tumefaciens protein Atu4866 4 77 1.0E-35 T 12-10-2018 IPR020955 Uncharacterised protein family Atu4866 UA74_17335 c92a564b389189b975efb66f81458e14 323 Gene3D G3DSA:2.30.40.10 100 187 2.2E-6 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_17335 c92a564b389189b975efb66f81458e14 323 SUPERFAMILY SSF51338 95 214 4.9E-10 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UA74_17335 c92a564b389189b975efb66f81458e14 323 Gene3D G3DSA:2.40.128.290 3 78 1.1E-34 T 12-10-2018 IPR038646 Atu4866-like superfamily UA74_17335 c92a564b389189b975efb66f81458e14 323 Gene3D G3DSA:2.40.128.290 247 322 2.0E-32 T 12-10-2018 IPR038646 Atu4866-like superfamily UA74_05575 1ccdadd697754feeeac86574106b1a95 405 Gene3D G3DSA:2.60.120.650 24 233 9.0E-41 T 12-10-2018 UA74_05575 1ccdadd697754feeeac86574106b1a95 405 Pfam PF08007 Cupin superfamily protein 128 274 1.3E-27 T 12-10-2018 IPR003347 JmjC domain UA74_05575 1ccdadd697754feeeac86574106b1a95 405 SUPERFAMILY SSF51197 72 269 2.47E-31 T 12-10-2018 UA74_27140 abb3bf247471f58df3ec778b3193a2ab 255 Pfam PF01061 ABC-2 type transporter 15 222 3.6E-18 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_27140 abb3bf247471f58df3ec778b3193a2ab 255 PIRSF PIRSF006648 1 254 7.3E-20 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_04480 d4c45844230938275bf7e768bc480fc6 212 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 57 86 1.6E-9 T 12-10-2018 IPR019933 DivIVA domain UA74_08405 6bfedad0204ba59845831f99b707e9ee 373 Gene3D G3DSA:3.40.50.2300 149 346 6.9E-92 T 12-10-2018 UA74_08405 6bfedad0204ba59845831f99b707e9ee 373 SUPERFAMILY SSF53822 44 347 2.51E-59 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_08405 6bfedad0204ba59845831f99b707e9ee 373 Pfam PF13407 Periplasmic binding protein domain 47 307 1.1E-56 T 12-10-2018 IPR025997 Periplasmic binding protein UA74_08405 6bfedad0204ba59845831f99b707e9ee 373 Gene3D G3DSA:3.40.50.2300 47 334 6.9E-92 T 12-10-2018 UA74_28765 a2419a6075206ebf9635f53eca105ab3 302 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 63 230 2.5E-54 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 UA74_28765 a2419a6075206ebf9635f53eca105ab3 302 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 59 234 1.7E-36 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 UA74_15010 f269155892cbcb86e39606f3fabc116b 596 SUPERFAMILY SSF140453 83 170 1.14E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_15010 f269155892cbcb86e39606f3fabc116b 596 Gene3D G3DSA:1.10.287.1060 78 169 1.6E-6 T 12-10-2018 UA74_07710 aed127feca4b5399a5eb5f0f1ba75bb8 301 PRINTS PR00164 ABC-2 type transport system membrane protein signature 70 91 1.2E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_07710 aed127feca4b5399a5eb5f0f1ba75bb8 301 PRINTS PR00164 ABC-2 type transport system membrane protein signature 150 175 1.2E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_07710 aed127feca4b5399a5eb5f0f1ba75bb8 301 PRINTS PR00164 ABC-2 type transport system membrane protein signature 224 243 1.2E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_07710 aed127feca4b5399a5eb5f0f1ba75bb8 301 PRINTS PR00164 ABC-2 type transport system membrane protein signature 244 263 1.2E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_07710 aed127feca4b5399a5eb5f0f1ba75bb8 301 Pfam PF01061 ABC-2 type transporter 51 265 4.0E-33 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_07710 aed127feca4b5399a5eb5f0f1ba75bb8 301 PIRSF PIRSF006648 31 301 9.6E-64 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_27260 7c3fc1c555271ff6042c4ba0ebd428ce 338 SUPERFAMILY SSF48452 99 296 1.63E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_27260 7c3fc1c555271ff6042c4ba0ebd428ce 338 Gene3D G3DSA:1.25.40.10 88 227 6.8E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_27260 7c3fc1c555271ff6042c4ba0ebd428ce 338 Gene3D G3DSA:1.25.40.10 228 314 7.4E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_27835 d307d7eb80666ce124113c6471e0f44a 485 Gene3D G3DSA:3.40.309.10 258 447 1.0E-94 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_27835 d307d7eb80666ce124113c6471e0f44a 485 Gene3D G3DSA:3.40.605.10 42 257 1.0E-94 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_27835 d307d7eb80666ce124113c6471e0f44a 485 Pfam PF00171 Aldehyde dehydrogenase family 32 449 7.4E-88 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_27835 d307d7eb80666ce124113c6471e0f44a 485 SUPERFAMILY SSF53720 16 447 1.96E-91 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_12525 7ac7203b6cba9ceab6029b45a8633405 398 Pfam PF01458 Uncharacterized protein family (UPF0051) 148 368 1.8E-70 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 UA74_12525 7ac7203b6cba9ceab6029b45a8633405 398 SUPERFAMILY SSF101960 41 393 1.2E-87 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily UA74_12525 7ac7203b6cba9ceab6029b45a8633405 398 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 115 385 3.5E-74 T 12-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 UA74_20105 ed297c6485e7b5abd0c7d25291b61cab 549 Pfam PF03929 PepSY-associated TM region 65 429 5.5E-63 T 12-10-2018 IPR005625 PepSY-associated TM protein UA74_26480 02bb045b0cd6ab2cdffb9705705d7295 272 SUPERFAMILY SSF89392 92 257 8.63E-9 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX UA74_15735 3cbe7f6bbca8d98e0c0ab626f3b56bff 179 Gene3D G3DSA:3.40.630.30 10 163 8.1E-35 T 12-10-2018 UA74_15735 3cbe7f6bbca8d98e0c0ab626f3b56bff 179 Pfam PF00583 Acetyltransferase (GNAT) family 31 140 9.6E-15 T 12-10-2018 IPR000182 GNAT domain UA74_15735 3cbe7f6bbca8d98e0c0ab626f3b56bff 179 SUPERFAMILY SSF55729 16 146 9.43E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_24220 f61dab20eeb9361858487fd012989fee 309 Gene3D G3DSA:1.10.3720.10 27 299 3.6E-52 T 12-10-2018 IPR035906 MetI-like superfamily UA74_24220 f61dab20eeb9361858487fd012989fee 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 293 6.2E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_24220 f61dab20eeb9361858487fd012989fee 309 SUPERFAMILY SSF161098 30 308 1.01E-54 T 12-10-2018 IPR035906 MetI-like superfamily UA74_17725 a291095e9319ce0c3977278a674a8ba0 221 Pfam PF08044 Domain of unknown function (DUF1707) 8 60 2.1E-16 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 UA74_10735 5fc0b7c18f7719b5316e7dd30e2f2430 215 SUPERFAMILY SSF55729 8 197 3.14E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_10735 5fc0b7c18f7719b5316e7dd30e2f2430 215 Gene3D G3DSA:3.40.630.30 8 199 3.4E-27 T 12-10-2018 UA74_10735 5fc0b7c18f7719b5316e7dd30e2f2430 215 Pfam PF00583 Acetyltransferase (GNAT) family 79 172 1.1E-6 T 12-10-2018 IPR000182 GNAT domain UA74_29230 db9cdd14b2b2a0d66b6f1cd128757ede 653 Gene3D G3DSA:1.50.10.10 249 628 1.4E-79 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_29230 db9cdd14b2b2a0d66b6f1cd128757ede 653 Pfam PF00723 Glycosyl hydrolases family 15 252 613 6.3E-52 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 UA74_29230 db9cdd14b2b2a0d66b6f1cd128757ede 653 SUPERFAMILY SSF48208 234 617 1.49E-97 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_29405 d2e26625745a8080ed8cdc952f9ec205 62 Pfam PF04149 Domain of unknown function (DUF397) 10 60 4.4E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_00060 9a798d8a2000177c66f36269f365906e 279 Gene3D G3DSA:3.40.50.150 51 245 5.6E-29 T 12-10-2018 UA74_00060 9a798d8a2000177c66f36269f365906e 279 Pfam PF13649 Methyltransferase domain 66 160 1.3E-11 T 12-10-2018 UA74_00060 9a798d8a2000177c66f36269f365906e 279 SUPERFAMILY SSF53335 28 278 9.07E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_03745 3767d3d407757cac54f875f540af6d6d 522 SUPERFAMILY SSF53955 140 308 1.15E-37 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_03745 3767d3d407757cac54f875f540af6d6d 522 Gene3D G3DSA:1.10.530.10 154 319 6.0E-8 T 12-10-2018 UA74_03745 3767d3d407757cac54f875f540af6d6d 522 Pfam PF13406 Transglycosylase SLT domain 225 274 1.1E-6 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 UA74_09960 732344b9f20d4d0ce80ed3882cb776f9 450 Pfam PF01757 Acyltransferase family 89 425 1.5E-13 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_22065 ba639bde2c36be66779f245b65c6b008 325 SUPERFAMILY SSF51430 8 308 7.07E-101 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_22065 ba639bde2c36be66779f245b65c6b008 325 Gene3D G3DSA:3.20.20.100 6 324 1.2E-116 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_22065 ba639bde2c36be66779f245b65c6b008 325 PRINTS PR00069 Aldo-keto reductase signature 241 265 1.0E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_22065 ba639bde2c36be66779f245b65c6b008 325 PRINTS PR00069 Aldo-keto reductase signature 42 66 1.0E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_22065 ba639bde2c36be66779f245b65c6b008 325 PRINTS PR00069 Aldo-keto reductase signature 108 126 1.0E-5 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UA74_22065 ba639bde2c36be66779f245b65c6b008 325 Pfam PF00248 Aldo/keto reductase family 13 307 5.0E-77 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 Gene3D G3DSA:2.120.10.30 547 666 7.4E-10 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 Gene3D G3DSA:2.120.10.30 381 545 4.3E-19 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 SUPERFAMILY SSF82171 75 428 6.28E-24 T 12-10-2018 UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 Pfam PF07676 WD40-like Beta Propeller Repeat 437 458 0.019 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 Pfam PF07676 WD40-like Beta Propeller Repeat 552 570 0.014 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 Pfam PF07676 WD40-like Beta Propeller Repeat 149 181 3.2E-8 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 Pfam PF07676 WD40-like Beta Propeller Repeat 490 509 2.0E-5 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 Pfam PF07676 WD40-like Beta Propeller Repeat 610 632 0.22 T 12-10-2018 IPR011659 WD40-like Beta Propeller UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 SUPERFAMILY SSF69304 380 661 1.31E-26 T 12-10-2018 UA74_20845 f87645fc7893992b33b1e7222b72991d 1038 Gene3D G3DSA:2.120.10.30 30 275 6.6E-32 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_15635 3e3ce4e7ec1244ee501c2191516ebd63 128 SUPERFAMILY SSF47413 8 68 4.3E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_15635 3e3ce4e7ec1244ee501c2191516ebd63 128 Gene3D G3DSA:1.10.260.40 7 70 5.5E-6 T 12-10-2018 UA74_18125 ebb9c3315c884b3f4691a7ce9ef5be9b 418 Gene3D G3DSA:3.30.565.10 288 414 7.4E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_18125 ebb9c3315c884b3f4691a7ce9ef5be9b 418 Pfam PF07730 Histidine kinase 212 277 6.2E-17 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UA74_18125 ebb9c3315c884b3f4691a7ce9ef5be9b 418 SUPERFAMILY SSF55874 294 413 7.74E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_14000 73d846c602965abbfc81c5345abc39f0 266 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 14 266 1.3E-114 T 12-10-2018 IPR022292 Conserved hypothetical protein CHP03843 UA74_00415 3e74e4dc1205fdfaa3d5ab6319c741c2 539 Pfam PF00474 Sodium:solute symporter family 48 457 1.0E-93 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UA74_00415 3e74e4dc1205fdfaa3d5ab6319c741c2 539 Gene3D G3DSA:1.20.1730.10 35 487 3.7E-55 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily UA74_00415 3e74e4dc1205fdfaa3d5ab6319c741c2 539 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 48 457 4.1E-58 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UA74_15730 c2abb92be6ab2484737e91e525dd9668 161 Pfam PF02698 DUF218 domain 1 87 1.1E-15 T 12-10-2018 IPR003848 Domain of unknown function DUF218 UA74_15730 c2abb92be6ab2484737e91e525dd9668 161 Gene3D G3DSA:3.40.50.620 8 98 5.2E-17 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UA74_05925 76e544ed4e7022242e1886f0057b0f88 48 Gene3D G3DSA:2.60.110.10 1 48 1.1E-15 T 12-10-2018 IPR037176 Osmotin/thaumatin-like superfamily UA74_05925 76e544ed4e7022242e1886f0057b0f88 48 Pfam PF16483 Beta-1,3-glucanase 2 45 4.8E-15 T 12-10-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 UA74_02455 93d030a20312756e4ff793082ebb565d 367 Gene3D G3DSA:3.40.50.1100 58 164 4.7E-66 T 12-10-2018 UA74_02455 93d030a20312756e4ff793082ebb565d 367 SUPERFAMILY SSF53686 30 342 6.16E-70 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UA74_02455 93d030a20312756e4ff793082ebb565d 367 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 32 322 9.3E-47 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UA74_02455 93d030a20312756e4ff793082ebb565d 367 Gene3D G3DSA:3.40.50.1100 41 330 4.7E-66 T 12-10-2018 UA74_19570 eb0f4091b7eb89afec4efd181989e9ec 368 Gene3D G3DSA:1.25.40.290 122 240 1.2E-30 T 12-10-2018 UA74_19570 eb0f4091b7eb89afec4efd181989e9ec 368 SUPERFAMILY SSF48371 40 241 3.06E-30 T 12-10-2018 IPR016024 Armadillo-type fold UA74_04495 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 189 201 7.9E-9 T 12-10-2018 UA74_04495 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 227 239 7.9E-9 T 12-10-2018 UA74_04495 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 262 278 7.9E-9 T 12-10-2018 UA74_04495 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 288 305 7.9E-9 T 12-10-2018 UA74_04495 d10a279024ced7a6f9aef130ed1bc95b 450 PRINTS PR01217 Proline rich extensin signature 239 260 7.9E-9 T 12-10-2018 UA74_03890 0d34c216afb96d392663747ce2a69a44 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 297 2.3E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_03890 0d34c216afb96d392663747ce2a69a44 313 SUPERFAMILY SSF161098 72 299 1.57E-62 T 12-10-2018 IPR035906 MetI-like superfamily UA74_03890 0d34c216afb96d392663747ce2a69a44 313 Gene3D G3DSA:1.10.3720.10 68 310 6.2E-73 T 12-10-2018 IPR035906 MetI-like superfamily UA74_05065 b1febe63ba018d4d07afc82d4cf46c5e 334 Gene3D G3DSA:3.40.50.300 106 176 1.3E-5 T 12-10-2018 UA74_05065 b1febe63ba018d4d07afc82d4cf46c5e 334 SUPERFAMILY SSF53795 108 168 4.27E-8 T 12-10-2018 UA74_09725 9cd03a3a74dd44769443877e43ad1559 212 Gene3D G3DSA:3.40.50.1240 1 176 6.8E-32 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_09725 9cd03a3a74dd44769443877e43ad1559 212 SUPERFAMILY SSF53254 5 174 4.71E-32 T 12-10-2018 IPR029033 Histidine phosphatase superfamily UA74_09725 9cd03a3a74dd44769443877e43ad1559 212 SMART SM00855 4 149 9.8E-7 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_09725 9cd03a3a74dd44769443877e43ad1559 212 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 155 8.2E-29 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UA74_11285 01d895538ba6b974f128df1fdfc0a759 293 SUPERFAMILY SSF81345 9 273 1.7E-17 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_11285 01d895538ba6b974f128df1fdfc0a759 293 Pfam PF00950 ABC 3 transport family 9 274 2.9E-41 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UA74_24175 6169445075a2d2aa057df23883c8fb7a 441 Gene3D G3DSA:3.40.190.10 58 356 5.4E-102 T 12-10-2018 UA74_24175 6169445075a2d2aa057df23883c8fb7a 441 Gene3D G3DSA:3.40.190.10 151 417 5.4E-102 T 12-10-2018 UA74_24175 6169445075a2d2aa057df23883c8fb7a 441 Pfam PF13416 Bacterial extracellular solute-binding protein 57 334 3.7E-28 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_24175 6169445075a2d2aa057df23883c8fb7a 441 SUPERFAMILY SSF53850 43 423 1.58E-60 T 12-10-2018 UA74_18145 2868920dd7233ee779d86297cb031326 425 Pfam PF13416 Bacterial extracellular solute-binding protein 71 369 1.5E-34 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_18145 2868920dd7233ee779d86297cb031326 425 Gene3D G3DSA:3.40.190.10 167 404 5.0E-69 T 12-10-2018 UA74_18145 2868920dd7233ee779d86297cb031326 425 Gene3D G3DSA:3.40.190.10 71 382 5.0E-69 T 12-10-2018 UA74_18145 2868920dd7233ee779d86297cb031326 425 SUPERFAMILY SSF53850 53 405 1.32E-62 T 12-10-2018 UA74_14185 b6452d6003c4df060e03c85464f38fb7 735 Gene3D G3DSA:1.50.10.10 367 582 1.5E-7 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_14185 b6452d6003c4df060e03c85464f38fb7 735 SUPERFAMILY SSF48208 330 730 8.67E-50 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_07385 df994854cfbe98ae453ea6676e23aa47 169 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 30 146 7.5E-15 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_07385 df994854cfbe98ae453ea6676e23aa47 169 SUPERFAMILY SSF55961 16 167 4.66E-31 T 12-10-2018 UA74_07385 df994854cfbe98ae453ea6676e23aa47 169 Gene3D G3DSA:3.30.530.20 3 169 2.5E-33 T 12-10-2018 IPR023393 START-like domain superfamily UA74_20575 1c6e26d9edfe8ec3ac675658cd74a9df 1297 Pfam PF00271 Helicase conserved C-terminal domain 1020 1072 9.5E-6 T 12-10-2018 IPR001650 Helicase, C-terminal UA74_20575 1c6e26d9edfe8ec3ac675658cd74a9df 1297 Gene3D G3DSA:3.40.50.300 995 1109 1.3E-9 T 12-10-2018 UA74_20575 1c6e26d9edfe8ec3ac675658cd74a9df 1297 SUPERFAMILY SSF52540 512 1116 5.74E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_06305 cdb3545627a851d2af6c79acde0f098d 198 Gene3D G3DSA:1.10.10.10 63 198 3.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_06305 cdb3545627a851d2af6c79acde0f098d 198 SUPERFAMILY SSF46785 68 197 2.14E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_22945 efed824d723cd9cb2822a211db18914f 339 Pfam PF00248 Aldo/keto reductase family 25 336 7.7E-39 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain UA74_22945 efed824d723cd9cb2822a211db18914f 339 Gene3D G3DSA:3.20.20.100 18 339 1.1E-64 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_22945 efed824d723cd9cb2822a211db18914f 339 SUPERFAMILY SSF51430 26 337 1.31E-52 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UA74_22915 46e56cf8d99dcbdad75db6b6dc549ac6 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 301 4.4E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_22915 46e56cf8d99dcbdad75db6b6dc549ac6 314 SUPERFAMILY SSF161098 74 298 8.5E-57 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22915 46e56cf8d99dcbdad75db6b6dc549ac6 314 Gene3D G3DSA:1.10.3720.10 70 309 4.2E-61 T 12-10-2018 IPR035906 MetI-like superfamily UA74_13450 7cf60454a06ab93bd4d085ae4da5155f 478 Gene3D G3DSA:3.40.309.10 230 410 3.5E-180 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UA74_13450 7cf60454a06ab93bd4d085ae4da5155f 478 Gene3D G3DSA:3.40.605.10 9 475 3.5E-180 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UA74_13450 7cf60454a06ab93bd4d085ae4da5155f 478 SUPERFAMILY SSF53720 7 460 7.46E-77 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UA74_13450 7cf60454a06ab93bd4d085ae4da5155f 478 Pfam PF00171 Aldehyde dehydrogenase family 8 421 6.3E-33 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UA74_24985 c94d4a8f236c55503d76359ade3f96e9 264 Pfam PF14011 EspG family 15 256 1.4E-48 T 12-10-2018 IPR025734 EspG family UA74_17800 acc6a80b290e468695dc1066f624d5d1 377 SUPERFAMILY SSF52540 2 217 9.52E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_17800 acc6a80b290e468695dc1066f624d5d1 377 SMART SM00382 26 204 1.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_17800 acc6a80b290e468695dc1066f624d5d1 377 Gene3D G3DSA:3.40.50.300 1 227 1.7E-54 T 12-10-2018 UA74_17800 acc6a80b290e468695dc1066f624d5d1 377 Pfam PF00005 ABC transporter 18 156 2.2E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_14345 7c2013ed22dbb2915b11ce07e18afbae 471 Pfam PF00656 Caspase domain 57 223 2.6E-7 T 12-10-2018 UA74_14345 7c2013ed22dbb2915b11ce07e18afbae 471 SUPERFAMILY SSF52129 79 207 1.15E-8 T 12-10-2018 IPR029030 Caspase-like domain superfamily UA74_14345 7c2013ed22dbb2915b11ce07e18afbae 471 Gene3D G3DSA:3.40.50.1460 16 227 7.4E-10 T 12-10-2018 UA74_10210 0fcf4cdb00a58c5e572171cc895ad212 347 Pfam PF01794 Ferric reductase like transmembrane component 75 211 4.1E-12 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain UA74_07145 077bc252a50308a764c30260c8cf407a 342 Pfam PF12079 Protein of unknown function (DUF3558) 21 198 3.5E-8 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_13210 1941d125c44a71e0e192e45e1117401a 457 Pfam PF03601 Conserved hypothetical protein 698 141 438 5.4E-68 T 12-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 UA74_02690 a79716351ea12789b1104ca3d552fe69 397 Pfam PF02687 FtsX-like permease family 303 391 2.3E-12 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_02690 a79716351ea12789b1104ca3d552fe69 397 Pfam PF12704 MacB-like periplasmic core domain 31 194 1.9E-17 T 12-10-2018 IPR025857 MacB-like periplasmic core domain UA74_05650 bb32cf9fb91ed28b2adf526c8699dada 365 SUPERFAMILY SSF140453 25 98 4.45E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_05650 bb32cf9fb91ed28b2adf526c8699dada 365 Gene3D G3DSA:1.10.287.1060 23 109 8.4E-7 T 12-10-2018 UA74_10055 2f4f8518ceedfaa555cf398a94502061 185 Gene3D G3DSA:3.90.1570.10 11 175 5.8E-17 T 12-10-2018 UA74_10055 2f4f8518ceedfaa555cf398a94502061 185 Pfam PF05685 Putative restriction endonuclease 23 183 2.8E-20 T 12-10-2018 IPR008538 Domain of unknown function DUF820 UA74_10055 2f4f8518ceedfaa555cf398a94502061 185 SUPERFAMILY SSF52980 14 151 1.5E-18 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_04915 fa1c7c113eb79ff55f7307840322e461 164 SUPERFAMILY SSF46785 5 156 4.68E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_04915 fa1c7c113eb79ff55f7307840322e461 164 Gene3D G3DSA:1.10.10.10 3 85 1.9E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_04915 fa1c7c113eb79ff55f7307840322e461 164 Pfam PF03551 Transcriptional regulator PadR-like family 8 78 2.4E-7 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal UA74_07425 4e79bde52746e563afbdb1beaa75d8de 63 Pfam PF04149 Domain of unknown function (DUF397) 7 58 2.0E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_28715 0df9448dbac523ea3e597991e10e1797 163 SUPERFAMILY SSF55961 3 147 7.74E-34 T 12-10-2018 UA74_28715 0df9448dbac523ea3e597991e10e1797 163 Gene3D G3DSA:3.30.530.20 2 163 6.1E-38 T 12-10-2018 IPR023393 START-like domain superfamily UA74_28715 0df9448dbac523ea3e597991e10e1797 163 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 141 3.0E-15 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like UA74_11030 ebfbf9cd561584285b6cfde4e3d5835f 116 Pfam PF03992 Antibiotic biosynthesis monooxygenase 7 78 1.4E-8 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UA74_11030 ebfbf9cd561584285b6cfde4e3d5835f 116 SUPERFAMILY SSF54909 7 97 2.23E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_11030 ebfbf9cd561584285b6cfde4e3d5835f 116 Gene3D G3DSA:3.30.70.100 7 111 4.0E-12 T 12-10-2018 UA74_16955 38941fa0b09676d81e1346b7b6fc1794 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 5 432 2.5E-10 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit UA74_09555 e78a6ac639e577b62e641c6cefe3fe9b 272 Pfam PF04012 PspA/IM30 family 3 240 2.5E-50 T 12-10-2018 IPR007157 PspA/IM30 UA74_03365 7a1884af1c349520c3e4c855df029337 132 SUPERFAMILY SSF55961 3 130 6.05E-12 T 12-10-2018 UA74_03365 7a1884af1c349520c3e4c855df029337 132 Gene3D G3DSA:3.30.530.20 12 131 6.3E-11 T 12-10-2018 IPR023393 START-like domain superfamily UA74_00470 3f65266c6b6c2bf378e30dbf78f926e3 271 Pfam PF14011 EspG family 14 259 9.9E-44 T 12-10-2018 IPR025734 EspG family UA74_29330 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 Gene3D G3DSA:3.40.640.10 3 254 2.2E-74 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_29330 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 PIRSF PIRSF017617 1 337 2.9E-105 T 12-10-2018 IPR023603 Threonine aldolase UA74_29330 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 SUPERFAMILY SSF53383 7 336 3.35E-90 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_29330 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 Gene3D G3DSA:3.90.1150.10 255 337 3.9E-18 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UA74_29330 1d6d7a31fe90d4fe7a58f2c13190bc3a 337 Pfam PF01212 Beta-eliminating lyase 8 292 5.4E-72 T 12-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 UA74_00390 3f0e8b05856c0c2014950671ed6cdda1 294 Pfam PF14219 Domain of unknown function (DUF4328) 101 257 1.4E-35 T 12-10-2018 IPR025565 Domain of unknown function DUF4328 UA74_20355 32e68d7266a62c41d87f2bc2c4ba06e1 202 Gene3D G3DSA:1.10.357.10 57 196 3.5E-28 T 12-10-2018 UA74_20355 32e68d7266a62c41d87f2bc2c4ba06e1 202 SUPERFAMILY SSF46689 3 76 2.74E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_20355 32e68d7266a62c41d87f2bc2c4ba06e1 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 3.2E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_20355 32e68d7266a62c41d87f2bc2c4ba06e1 202 SUPERFAMILY SSF48498 79 193 2.86E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UA74_20355 32e68d7266a62c41d87f2bc2c4ba06e1 202 Gene3D G3DSA:1.10.10.60 6 56 5.7E-12 T 12-10-2018 UA74_03830 6313d300007c76f28c16f5dc576258f6 499 Gene3D G3DSA:2.60.40.10 326 440 1.1E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_24325 175fcd623fd58c14de5adc78af34c39a 320 SUPERFAMILY SSF46785 5 62 3.95E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_24325 175fcd623fd58c14de5adc78af34c39a 320 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UA74_24325 175fcd623fd58c14de5adc78af34c39a 320 Gene3D G3DSA:1.10.10.10 4 64 2.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_24325 175fcd623fd58c14de5adc78af34c39a 320 Pfam PF13280 WYL domain 141 312 3.1E-26 T 12-10-2018 IPR026881 WYL domain UA74_24325 175fcd623fd58c14de5adc78af34c39a 320 Pfam PF08279 HTH domain 7 61 1.3E-18 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 UA74_19285 6f342ea4fb0b25aeef6c2faeedad6a2f 306 Pfam PF09362 Domain of unknown function (DUF1996) 54 261 1.0E-48 T 12-10-2018 IPR018535 Domain of unknown function DUF1996 UA74_26730 162876aa5b37d51c83de1acb0dc22ca4 347 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 310 4.5E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_29930 6bf38be5fffdd4b0a8e08e90cc980299 187 Pfam PF04402 Protein of unknown function (DUF541) 2 173 7.0E-22 T 12-10-2018 IPR007497 Protein of unknown function DUF541 UA74_29930 6bf38be5fffdd4b0a8e08e90cc980299 187 Gene3D G3DSA:3.30.110.170 70 165 6.0E-9 T 12-10-2018 UA74_11395 3ed9cfcf029df85fa073b2ddd1f7021f 158 SUPERFAMILY SSF103256 3 137 1.44E-46 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 UA74_11395 3ed9cfcf029df85fa073b2ddd1f7021f 158 Pfam PF02577 Bifunctional nuclease 7 128 7.0E-45 T 12-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 UA74_11395 3ed9cfcf029df85fa073b2ddd1f7021f 158 Gene3D G3DSA:3.10.690.10 1 141 2.5E-46 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 UA74_15100 157febc082565c35ca30ff1beb73a52d 243 SUPERFAMILY SSF51261 101 235 2.2E-47 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_15100 157febc082565c35ca30ff1beb73a52d 243 Gene3D G3DSA:2.70.70.10 90 238 5.9E-44 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_15100 157febc082565c35ca30ff1beb73a52d 243 Pfam PF01551 Peptidase family M23 137 231 9.8E-31 T 12-10-2018 IPR016047 Peptidase M23 UA74_26225 8e44047f2e96de2c11a15fbcd53a6405 110 Pfam PF02656 Domain of unknown function (DUF202) 12 73 5.1E-12 T 12-10-2018 IPR003807 Domain of unknown function DUF202 UA74_17595 cba9779bc76d0173d768000a16591045 97 SUPERFAMILY SSF47336 12 80 9.95E-13 T 12-10-2018 IPR036736 ACP-like superfamily UA74_17595 cba9779bc76d0173d768000a16591045 97 Pfam PF00550 Phosphopantetheine attachment site 16 80 1.1E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain UA74_17595 cba9779bc76d0173d768000a16591045 97 Gene3D G3DSA:1.10.1200.10 12 90 8.0E-16 T 12-10-2018 IPR036736 ACP-like superfamily UA74_16215 38b45ad8b883390aac2cb641f3010a47 109 SUPERFAMILY SSF53098 35 99 3.79E-8 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_16215 38b45ad8b883390aac2cb641f3010a47 109 ProSitePatterns PS01043 Transposases, IS30 family, signature. 44 60 - T 12-10-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 UA74_18755 9737651f3d07c3ae6a47a1a0df37781b 308 Gene3D G3DSA:3.30.450.40 141 308 1.7E-46 T 12-10-2018 IPR029016 GAF-like domain superfamily UA74_18755 9737651f3d07c3ae6a47a1a0df37781b 308 SUPERFAMILY SSF55781 144 307 3.14E-39 T 12-10-2018 UA74_18755 9737651f3d07c3ae6a47a1a0df37781b 308 Pfam PF01614 Bacterial transcriptional regulator 187 305 3.7E-25 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal UA74_06230 5f812ccdf3149e410c22981559a47b67 317 Gene3D G3DSA:2.120.10.30 5 316 1.1E-57 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UA74_06230 5f812ccdf3149e410c22981559a47b67 317 SUPERFAMILY SSF63829 15 305 2.13E-41 T 12-10-2018 UA74_06230 5f812ccdf3149e410c22981559a47b67 317 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 18 287 3.3E-52 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region UA74_06230 5f812ccdf3149e410c22981559a47b67 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 268 286 3.8E-17 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_06230 5f812ccdf3149e410c22981559a47b67 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 226 243 3.8E-17 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_06230 5f812ccdf3149e410c22981559a47b67 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 18 35 3.8E-17 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_06230 5f812ccdf3149e410c22981559a47b67 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 186 206 3.8E-17 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) UA74_12580 584fbe817e6ca45532e6ea388749946a 832 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 22 280 7.7E-15 T 12-10-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51|MetaCyc: PWY-6807 UA74_12580 584fbe817e6ca45532e6ea388749946a 832 Gene3D G3DSA:2.70.98.50 29 324 6.4E-78 T 12-10-2018 UA74_12580 584fbe817e6ca45532e6ea388749946a 832 Gene3D G3DSA:1.50.10.10 25 767 6.4E-78 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UA74_12580 584fbe817e6ca45532e6ea388749946a 832 SUPERFAMILY SSF48208 305 771 5.83E-47 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UA74_13940 92ddfb1a675c0c301bfb9ec77096b285 351 Gene3D G3DSA:1.10.3720.10 111 345 1.7E-20 T 12-10-2018 IPR035906 MetI-like superfamily UA74_13940 92ddfb1a675c0c301bfb9ec77096b285 351 SUPERFAMILY SSF161098 116 337 1.44E-14 T 12-10-2018 IPR035906 MetI-like superfamily UA74_13940 92ddfb1a675c0c301bfb9ec77096b285 351 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 140 349 6.2E-40 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_14975 6139ae0fc4e3982e70bee7da0022e977 147 SUPERFAMILY SSF54427 5 132 3.25E-33 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_14975 6139ae0fc4e3982e70bee7da0022e977 147 Gene3D G3DSA:3.10.450.50 3 134 8.1E-37 T 12-10-2018 UA74_14975 6139ae0fc4e3982e70bee7da0022e977 147 Pfam PF12680 SnoaL-like domain 9 117 1.5E-15 T 12-10-2018 IPR037401 SnoaL-like domain UA74_06955 1f1c8a0b00c47876ca0ea284c588d3a6 309 Pfam PF11303 Protein of unknown function (DUF3105) 84 210 1.3E-41 T 12-10-2018 IPR021454 Protein of unknown function DUF3105 UA74_21675 b138a5de9512b4c8a58935f839d5dd4b 562 Pfam PF03235 Protein of unknown function DUF262 22 212 4.1E-26 T 12-10-2018 IPR004919 Domain of unknown function DUF262 UA74_00425 737c3f0aca10c73918e5d34abcbb6503 605 Pfam PF00474 Sodium:solute symporter family 308 499 9.3E-15 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UA74_00425 737c3f0aca10c73918e5d34abcbb6503 605 Pfam PF00474 Sodium:solute symporter family 35 203 4.9E-28 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UA74_00425 737c3f0aca10c73918e5d34abcbb6503 605 Gene3D G3DSA:1.20.1730.10 23 268 2.0E-28 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily UA74_00425 737c3f0aca10c73918e5d34abcbb6503 605 Gene3D G3DSA:1.20.1730.10 277 564 2.4E-16 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily UA74_24195 dbd925f7f489ea82dc4720b29e7cd55d 680 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 16 363 3.9E-103 T 12-10-2018 IPR016624 Uncharacterised conserved protein UCP014753 UA74_04625 3e12285a4ce3a9c614eb599614bd3114 322 SUPERFAMILY SSF161098 37 311 4.58E-48 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04625 3e12285a4ce3a9c614eb599614bd3114 322 Gene3D G3DSA:1.10.3720.10 31 309 1.3E-52 T 12-10-2018 IPR035906 MetI-like superfamily UA74_04625 3e12285a4ce3a9c614eb599614bd3114 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 309 4.8E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_20435 532240eacf27c68e4b52d14772450707 235 Pfam PF11139 Sap, sulfolipid-1-addressing protein 9 229 4.3E-31 T 12-10-2018 IPR021315 Glycolipid exporter Gap/Sap UA74_08470 48ffcee7291449aa0d28f6f2565fbd47 231 Pfam PF12502 Protein of unknown function (DUF3710) 30 195 2.9E-60 T 12-10-2018 IPR022183 Protein of unknown function DUF3710 UA74_17960 716875f0f8ae71aa5bae628d805e84f8 92 Pfam PF09851 Short C-terminal domain 60 81 9.8E-7 T 12-10-2018 IPR018649 SHOCT domain UA74_25405 6f2b7cae7c053f55e3b808559624d67d 272 Pfam PF05552 Conserved TM helix 11 55 1.5E-12 T 12-10-2018 IPR008910 Conserved TM helix UA74_25405 6f2b7cae7c053f55e3b808559624d67d 272 Pfam PF05552 Conserved TM helix 103 145 1.4E-7 T 12-10-2018 IPR008910 Conserved TM helix UA74_11940 50d0bf2eb43bf57dcc6aec70ec36d4f0 401 Pfam PF13556 PucR C-terminal helix-turn-helix domain 334 392 1.2E-16 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UA74_11940 50d0bf2eb43bf57dcc6aec70ec36d4f0 401 Gene3D G3DSA:1.10.10.2840 266 398 8.6E-21 T 12-10-2018 UA74_09180 1dbe72d8d0d966dcead63ba0d040837f 278 Pfam PF03883 Peroxide stress protein YaaA 26 236 1.2E-32 T 12-10-2018 IPR005583 Peroxide stress protein YaaA UA74_11505 6ecfa426b156343d6a06d3a97d7ec2be 248 SUPERFAMILY SSF53448 14 232 2.09E-20 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UA74_11505 6ecfa426b156343d6a06d3a97d7ec2be 248 Pfam PF12804 MobA-like NTP transferase domain 18 210 1.3E-23 T 12-10-2018 IPR025877 MobA-like NTP transferase UA74_07130 6c5713049c8be7e126e1673daa075b92 219 Gene3D G3DSA:2.70.180.20 1 89 3.1E-19 T 12-10-2018 UA74_07130 6c5713049c8be7e126e1673daa075b92 219 Hamap MF_00722 Endonuclease NucS [nucS]. 1 211 31.168 T 12-10-2018 IPR002793 Endonuclease NucS GO:0004519 UA74_07130 6c5713049c8be7e126e1673daa075b92 219 Gene3D G3DSA:3.40.1350.10 94 205 6.7E-25 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 UA74_07130 6c5713049c8be7e126e1673daa075b92 219 Pfam PF01939 Endonuclease NucS 1 219 8.4E-82 T 12-10-2018 IPR002793 Endonuclease NucS GO:0004519 UA74_26220 8912d24fe99bfcdf9706dea44f4988fd 124 Pfam PF02656 Domain of unknown function (DUF202) 25 88 2.2E-14 T 12-10-2018 IPR003807 Domain of unknown function DUF202 UA74_00145 65c486422df058515158722dd50de7dd 481 Pfam PF01098 Cell cycle protein 89 453 6.0E-85 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UA74_20300 b820403acd8e3f99017c3c277744570f 463 PRINTS PR00359 B-class P450 signature 172 187 1.3E-13 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20300 b820403acd8e3f99017c3c277744570f 463 PRINTS PR00359 B-class P450 signature 205 227 1.3E-13 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20300 b820403acd8e3f99017c3c277744570f 463 PRINTS PR00359 B-class P450 signature 155 171 1.3E-13 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20300 b820403acd8e3f99017c3c277744570f 463 PRINTS PR00359 B-class P450 signature 345 354 1.3E-13 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20300 b820403acd8e3f99017c3c277744570f 463 PRINTS PR00359 B-class P450 signature 109 120 1.3E-13 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_20300 b820403acd8e3f99017c3c277744570f 463 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_20300 b820403acd8e3f99017c3c277744570f 463 Gene3D G3DSA:1.10.630.10 20 414 1.1E-86 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_20300 b820403acd8e3f99017c3c277744570f 463 SUPERFAMILY SSF48264 12 405 5.11E-61 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_11855 6ce46b4ca40d8ae14f81a987176b70f1 637 Gene3D G3DSA:2.60.40.10 49 141 3.6E-19 T 12-10-2018 IPR013783 Immunoglobulin-like fold UA74_11855 6ce46b4ca40d8ae14f81a987176b70f1 637 SUPERFAMILY SSF69318 163 591 1.13E-16 T 12-10-2018 UA74_24725 62b33864d6e6b7aee59303bcee58ad14 291 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 44 282 9.8E-46 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UA74_24725 62b33864d6e6b7aee59303bcee58ad14 291 SUPERFAMILY SSF51695 38 288 4.71E-72 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_24725 62b33864d6e6b7aee59303bcee58ad14 291 Gene3D G3DSA:3.20.20.190 24 291 2.2E-75 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UA74_26725 73c28437f71604cf8f7bed1d53987d3e 361 Pfam PF13407 Periplasmic binding protein domain 62 318 7.8E-54 T 12-10-2018 IPR025997 Periplasmic binding protein UA74_26725 73c28437f71604cf8f7bed1d53987d3e 361 SUPERFAMILY SSF53822 60 361 2.57E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_26725 73c28437f71604cf8f7bed1d53987d3e 361 Gene3D G3DSA:3.40.50.2300 162 361 2.8E-119 T 12-10-2018 UA74_26725 73c28437f71604cf8f7bed1d53987d3e 361 Gene3D G3DSA:3.40.50.2300 62 345 2.8E-119 T 12-10-2018 UA74_26725 73c28437f71604cf8f7bed1d53987d3e 361 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 62 361 4.1E-114 T 12-10-2018 IPR013459 Rhamnose ABC transporter, substrate-binding protein RhaS GO:0015762 UA74_16630 c9c57d072bbe6f661bc7a70e6c2d7608 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 260 2.9E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_16630 c9c57d072bbe6f661bc7a70e6c2d7608 270 SUPERFAMILY SSF161098 68 246 1.2E-11 T 12-10-2018 IPR035906 MetI-like superfamily UA74_27190 41614781eba1303676f32f95d7362e6e 143 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 109 1.9E-25 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like UA74_12745 1861e56ececa1578165b13a13ba7cdb0 183 Gene3D G3DSA:2.30.110.10 48 169 1.2E-11 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UA74_12745 1861e56ececa1578165b13a13ba7cdb0 183 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 52 170 1.7E-32 T 12-10-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative UA74_12745 1861e56ececa1578165b13a13ba7cdb0 183 SUPERFAMILY SSF50475 55 146 3.54E-10 T 12-10-2018 UA74_25730 242ea2f2c2040f93d9b1c3715d58c140 247 Pfam PF10067 Predicted membrane protein (DUF2306) 59 208 4.3E-39 T 12-10-2018 IPR018750 Protein of unknown function DUF2306, membrane UA74_19530 40a6039c2bb5f9a790e3aa1d8dbc4503 419 Gene3D G3DSA:3.40.190.10 28 415 1.7E-62 T 12-10-2018 UA74_19530 40a6039c2bb5f9a790e3aa1d8dbc4503 419 Pfam PF01547 Bacterial extracellular solute-binding protein 48 329 3.9E-28 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_19530 40a6039c2bb5f9a790e3aa1d8dbc4503 419 SUPERFAMILY SSF53850 21 416 1.03E-61 T 12-10-2018 UA74_01285 2b36870a9c475202cae0bb78459d6e4f 188 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 41 155 6.2E-28 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III UA74_24730 cbe09a0b77a3151659e2eb8c64f3d3bd 367 Gene3D G3DSA:3.40.80.10 168 362 4.1E-48 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_24730 cbe09a0b77a3151659e2eb8c64f3d3bd 367 SMART SM00701 168 326 1.5E-8 T 12-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_24730 cbe09a0b77a3151659e2eb8c64f3d3bd 367 SUPERFAMILY SSF55846 170 362 8.49E-39 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_24730 cbe09a0b77a3151659e2eb8c64f3d3bd 367 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 190 348 4.6E-17 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UA74_17190 012e88fcae9444f2c023ecac22781b28 644 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 362 607 3.1E-82 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related UA74_17190 012e88fcae9444f2c023ecac22781b28 644 Pfam PF05425 Copper resistance protein D 215 310 4.4E-11 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 UA74_07295 6ae5dbbf23d497d66b549ef0b7e5a366 96 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 47 6.6E-6 T 12-10-2018 UA74_09300 191f4509fe7afd368911b708faddbd65 67 Pfam PF04149 Domain of unknown function (DUF397) 11 62 5.3E-15 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_04190 2eac7d8e3c4151026acb337d4169bd77 327 Pfam PF02646 RmuC family 61 264 5.3E-38 T 12-10-2018 IPR003798 DNA recombination RmuC UA74_22440 07cbf5d7c4df5628b1adbff04fdcaa1e 132 SUPERFAMILY SSF142906 1 118 2.22E-33 T 12-10-2018 IPR038056 YjbR-like superfamily UA74_22440 07cbf5d7c4df5628b1adbff04fdcaa1e 132 Gene3D G3DSA:3.90.1150.30 1 125 8.3E-38 T 12-10-2018 IPR038056 YjbR-like superfamily UA74_22440 07cbf5d7c4df5628b1adbff04fdcaa1e 132 Pfam PF04237 YjbR 11 103 1.8E-25 T 12-10-2018 IPR007351 Uncharacterised protein YjbR UA74_03660 119be9c21ef5fade5f4c174cd3f6dc56 200 Gene3D G3DSA:3.90.1570.10 5 146 9.2E-19 T 12-10-2018 UA74_03660 119be9c21ef5fade5f4c174cd3f6dc56 200 Pfam PF05685 Putative restriction endonuclease 20 168 7.6E-23 T 12-10-2018 IPR008538 Domain of unknown function DUF820 UA74_03660 119be9c21ef5fade5f4c174cd3f6dc56 200 SUPERFAMILY SSF52980 10 144 4.45E-20 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_10765 23c2020280b8543dc9633b2f6ed13e44 203 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 1.3E-10 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_10765 23c2020280b8543dc9633b2f6ed13e44 203 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UA74_10765 23c2020280b8543dc9633b2f6ed13e44 203 Gene3D G3DSA:1.20.120.1760 7 203 2.0E-58 T 12-10-2018 UA74_13610 13268867d06d59285bcaa1504601e1ff 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 284 9.5E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_14325 078bca0197efb716eb2ff5858021be6b 175 Gene3D G3DSA:1.20.120.450 4 168 4.6E-5 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_14325 078bca0197efb716eb2ff5858021be6b 175 Pfam PF12867 DinB superfamily 12 162 4.1E-21 T 12-10-2018 IPR024775 DinB-like domain UA74_14325 078bca0197efb716eb2ff5858021be6b 175 SUPERFAMILY SSF109854 6 156 2.93E-6 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_24110 73bf37a2866c76cf2bc5bccee0191cc0 417 Pfam PF01566 Natural resistance-associated macrophage protein 48 391 3.9E-73 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UA74_11745 175c89172fe8c11344783ca1f562a250 150 Gene3D G3DSA:3.30.565.10 22 144 6.0E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_11745 175c89172fe8c11344783ca1f562a250 150 Pfam PF13581 Histidine kinase-like ATPase domain 29 96 2.6E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UA74_19795 27d3adf79088d390b10f995e9593e959 114 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 39 77 2.7E-6 T 12-10-2018 IPR026496 Putative ATP-grasp target RiPP UA74_28340 119802e9add65ac379a925b23440660d 483 Pfam PF11228 Protein of unknown function (DUF3027) 76 266 5.7E-80 T 12-10-2018 IPR021391 Protein of unknown function DUF3027 UA74_06485 208c41ee0221217198283fd22d37a18b 268 SUPERFAMILY SSF64288 85 237 3.26E-18 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_06485 208c41ee0221217198283fd22d37a18b 268 Gene3D G3DSA:3.40.1410.10 82 241 1.2E-29 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UA74_00070 52d7145c0ff46f117a389d3f2be18ffd 385 Pfam PF04235 Protein of unknown function (DUF418) 225 379 6.8E-38 T 12-10-2018 IPR007349 Domain of unknown function DUF418 UA74_21545 73547ad1265771677232ca550d731439 297 SUPERFAMILY SSF111331 4 292 4.45E-75 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily UA74_21545 73547ad1265771677232ca550d731439 297 Pfam PF01513 ATP-NAD kinase 59 270 8.2E-59 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 UA74_21545 73547ad1265771677232ca550d731439 297 Hamap MF_00361 NAD kinase [nadK]. 3 286 27.823 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 UA74_21545 73547ad1265771677232ca550d731439 297 Gene3D G3DSA:3.40.50.10330 58 284 9.1E-88 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 UA74_21545 73547ad1265771677232ca550d731439 297 Gene3D G3DSA:2.60.200.30 127 263 9.1E-88 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 UA74_04975 0600df9cca125253c7a3c6ee30aa1ded 653 Gene3D G3DSA:2.130.10.10 3 298 1.5E-10 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_04975 0600df9cca125253c7a3c6ee30aa1ded 653 SUPERFAMILY SSF51004 65 308 6.8E-14 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily UA74_29865 359c3427c465b1dc7dfd5c9aea4f14c2 555 Gene3D G3DSA:1.20.1730.10 31 479 9.0E-31 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily UA74_24660 fba0e36ed2d3386b40831dab630eafc0 567 Pfam PF05960 Bacterial protein of unknown function (DUF885) 27 564 3.7E-161 T 12-10-2018 IPR010281 Protein of unknown function DUF885 UA74_30230 f445def35fbe90cda793a57523a0c549 574 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 47 562 1.9E-78 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_30230 f445def35fbe90cda793a57523a0c549 574 Pfam PF03023 MviN-like protein 74 517 2.6E-89 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_30230 f445def35fbe90cda793a57523a0c549 574 PRINTS PR01806 Virulence factor MviN signature 200 221 5.5E-23 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_30230 f445def35fbe90cda793a57523a0c549 574 PRINTS PR01806 Virulence factor MviN signature 78 97 5.5E-23 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_30230 f445def35fbe90cda793a57523a0c549 574 PRINTS PR01806 Virulence factor MviN signature 311 337 5.5E-23 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_30230 f445def35fbe90cda793a57523a0c549 574 PRINTS PR01806 Virulence factor MviN signature 408 427 5.5E-23 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_30230 f445def35fbe90cda793a57523a0c549 574 PRINTS PR01806 Virulence factor MviN signature 97 113 5.5E-23 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_30230 f445def35fbe90cda793a57523a0c549 574 PRINTS PR01806 Virulence factor MviN signature 176 200 5.5E-23 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ UA74_09120 a27f69ebb7f918717d0e68ce14730a13 311 SUPERFAMILY SSF55166 154 308 1.96E-23 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_09120 a27f69ebb7f918717d0e68ce14730a13 311 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 228 307 1.5E-18 T 12-10-2018 IPR039561 Peptidase M15C GO:0008233 UA74_09120 a27f69ebb7f918717d0e68ce14730a13 311 Gene3D G3DSA:3.30.1380.10 168 307 1.1E-12 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UA74_11130 934cf0fd7d1e39294403ad7fbe4fead3 397 Pfam PF01757 Acyltransferase family 28 368 3.9E-17 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_21875 075c4233183abef61a9f317d54b5113f 263 SUPERFAMILY SSF51182 19 120 1.89E-13 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily UA74_21875 075c4233183abef61a9f317d54b5113f 263 Gene3D G3DSA:2.60.120.10 6 147 1.3E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold UA74_21875 075c4233183abef61a9f317d54b5113f 263 Pfam PF00190 Cupin 40 105 7.4E-6 T 12-10-2018 IPR006045 Cupin 1 GO:0045735 UA74_27355 b83aeaab5def9295312111c32a2e3e87 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 4.2E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_13925 35a5826b2c6ae0d252ee0ee197eab299 530 Pfam PF07690 Major Facilitator Superfamily 21 418 3.8E-52 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_13925 35a5826b2c6ae0d252ee0ee197eab299 530 Gene3D G3DSA:1.20.1720.10 18 227 1.4E-48 T 12-10-2018 UA74_13925 35a5826b2c6ae0d252ee0ee197eab299 530 SUPERFAMILY SSF103473 7 527 3.79E-65 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_13925 35a5826b2c6ae0d252ee0ee197eab299 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 7.2E-7 T 12-10-2018 UA74_13925 35a5826b2c6ae0d252ee0ee197eab299 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 409 428 7.2E-7 T 12-10-2018 UA74_13925 35a5826b2c6ae0d252ee0ee197eab299 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 7.2E-7 T 12-10-2018 UA74_13925 35a5826b2c6ae0d252ee0ee197eab299 530 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 7.2E-7 T 12-10-2018 UA74_13925 35a5826b2c6ae0d252ee0ee197eab299 530 Gene3D G3DSA:1.20.1250.20 266 442 1.8E-20 T 12-10-2018 UA74_13925 35a5826b2c6ae0d252ee0ee197eab299 530 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 427 2.6E-76 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UA74_09895 4bc733940a91077426cb571c0928f758 193 Pfam PF04978 Protein of unknown function (DUF664) 34 189 5.0E-40 T 12-10-2018 IPR007061 Protein of unknown function DUF664 UA74_09895 4bc733940a91077426cb571c0928f758 193 SUPERFAMILY SSF109854 19 188 6.87E-35 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_09895 4bc733940a91077426cb571c0928f758 193 Gene3D G3DSA:1.20.120.450 15 190 9.2E-29 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UA74_19820 9a1625efbebb231e6524149d2dc3b53c 279 PIRSF PIRSF001359 1 277 1.9E-76 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_19820 9a1625efbebb231e6524149d2dc3b53c 279 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 270 3.8E-69 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_19820 9a1625efbebb231e6524149d2dc3b53c 279 SUPERFAMILY SSF51569 2 273 4.4E-82 T 12-10-2018 UA74_19820 9a1625efbebb231e6524149d2dc3b53c 279 Gene3D G3DSA:3.20.20.70 1 277 5.5E-91 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UA74_19820 9a1625efbebb231e6524149d2dc3b53c 279 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 274 3.7E-84 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UA74_17420 437eab18955b67514edce4d9cc5c0aa2 302 Pfam PF12697 Alpha/beta hydrolase family 28 295 4.2E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_17420 437eab18955b67514edce4d9cc5c0aa2 302 SUPERFAMILY SSF53474 26 298 1.4E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_17420 437eab18955b67514edce4d9cc5c0aa2 302 Gene3D G3DSA:3.40.50.1820 25 300 6.7E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_01630 ce12fed056197d26c50d5b7dea8b24c7 340 SUPERFAMILY SSF56219 121 336 1.27E-27 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_01630 ce12fed056197d26c50d5b7dea8b24c7 340 Gene3D G3DSA:3.60.10.10 119 339 3.1E-32 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily UA74_01630 ce12fed056197d26c50d5b7dea8b24c7 340 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 132 329 6.6E-16 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase UA74_09955 2f9f8b93e6fb4ad2815ae0a709754a04 249 Pfam PF02517 CAAX protease self-immunity 119 230 2.4E-14 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 UA74_09955 2f9f8b93e6fb4ad2815ae0a709754a04 249 PIRSF PIRSF026622 4 44 2.9 T 12-10-2018 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type UA74_09955 2f9f8b93e6fb4ad2815ae0a709754a04 249 PIRSF PIRSF026622 43 244 1.2E-25 T 12-10-2018 IPR015837 Uncharacterised conserved protein UCP026622, CAAX protease-type UA74_27610 392a504d5e88413f7bcf1a6f08910af3 162 SUPERFAMILY SSF160424 14 151 1.27E-22 T 12-10-2018 IPR036170 Probable antitoxin YezG superfamily UA74_09450 565e309b6833c6c20ab1a77b0f2cbaec 74 TIGRFAM TIGR03898 lanti_MRSA_kill: type 2 lantibiotic, mersacidin/lichenicidin family 2 35 3.8E-9 T 12-10-2018 IPR027635 Type 2 lantibiotic, leader peptide domain GO:0042742 UA74_25535 d24a76824f092ca1db8d2132e3cd3c81 262 Pfam PF12483 E3 Ubiquitin ligase 95 252 6.4E-26 T 12-10-2018 IPR022170 E3 Ubiquitin ligase, GIDE-type GO:0004842|GO:0006996|GO:0016567 MetaCyc: PWY-7511|Reactome: R-HSA-5689880 UA74_19230 fd4cbb332192d823aecb253425f0fc95 419 Pfam PF05977 Transmembrane secretion effector 23 414 2.0E-20 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_19230 fd4cbb332192d823aecb253425f0fc95 419 Gene3D G3DSA:1.20.1250.20 26 410 1.1E-28 T 12-10-2018 UA74_19230 fd4cbb332192d823aecb253425f0fc95 419 SUPERFAMILY SSF103473 23 415 1.44E-32 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_08460 0aa689777d5c27848eeb9a8ca071813d 196 Pfam PF11292 Protein of unknown function (DUF3093) 26 165 5.6E-49 T 12-10-2018 IPR021443 Protein of unknown function DUF3093 UA74_23785 0c7b33cc50e636fdd66b0ffb9f81f594 432 Pfam PF01547 Bacterial extracellular solute-binding protein 55 340 5.2E-25 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_23785 0c7b33cc50e636fdd66b0ffb9f81f594 432 Gene3D G3DSA:3.40.190.10 151 424 2.4E-118 T 12-10-2018 UA74_23785 0c7b33cc50e636fdd66b0ffb9f81f594 432 SUPERFAMILY SSF53850 38 431 1.19E-56 T 12-10-2018 UA74_23785 0c7b33cc50e636fdd66b0ffb9f81f594 432 Gene3D G3DSA:3.40.190.10 41 379 2.4E-118 T 12-10-2018 UA74_05075 df83ca60867c4656c0ca80119b7d907c 283 SUPERFAMILY SSF56112 14 215 5.47E-20 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_21565 c0a093f43ad10ba4bea25f0f7a429f0e 401 Gene3D G3DSA:1.25.40.10 62 208 1.5E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_12035 51bbcf105a5b491d6b862b621a6613b5 141 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 8.6E-22 T 12-10-2018 IPR009293 Uncharacterised protein family UPF0478 UA74_23060 b706a9c293d42867ebb21d6b28837e8a 411 SUPERFAMILY SSF53756 147 318 5.02E-9 T 12-10-2018 UA74_08390 4212c664e7d2c5043ced7b762ef183c4 448 Pfam PF03631 Virulence factor BrkB 36 296 3.9E-43 T 12-10-2018 IPR017039 Virulence factor BrkB UA74_13375 0c3d6722effe883f210c3b332f733784 213 Pfam PF13649 Methyltransferase domain 44 135 2.3E-16 T 12-10-2018 UA74_13375 0c3d6722effe883f210c3b332f733784 213 Gene3D G3DSA:3.40.50.150 10 204 7.4E-37 T 12-10-2018 UA74_13375 0c3d6722effe883f210c3b332f733784 213 SUPERFAMILY SSF53335 9 183 1.38E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_10905 e3e8d2ab533c30a24c76a743416e994c 151 Pfam PF08592 Domain of unknown function (DUF1772) 19 147 7.3E-16 T 12-10-2018 UA74_15640 50c78dfbfcea185a634d88e09c29a38f 533 Gene3D G3DSA:1.10.260.40 14 73 1.1E-5 T 12-10-2018 UA74_05040 49ace632fd864e66d1634742014e15a8 159 SUPERFAMILY SSF102405 2 155 2.93E-11 T 12-10-2018 UA74_11100 a15b583026fe84c274eb9db693a0c80b 270 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 116 267 6.4E-26 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UA74_11100 a15b583026fe84c274eb9db693a0c80b 270 Gene3D G3DSA:2.40.100.10 111 269 8.2E-44 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily UA74_11100 a15b583026fe84c274eb9db693a0c80b 270 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 128 143 1.4E-5 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UA74_11100 a15b583026fe84c274eb9db693a0c80b 270 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 197 212 1.4E-5 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UA74_11100 a15b583026fe84c274eb9db693a0c80b 270 SUPERFAMILY SSF50891 115 269 1.61E-36 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily UA74_05270 3b314496c5d3802fbc66f9837307afa4 278 Pfam PF02517 CAAX protease self-immunity 119 210 4.4E-17 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 UA74_12115 82eaf36844b7d521e1483ea5261905ad 233 Pfam PF01478 Type IV leader peptidase family 96 203 7.1E-8 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 UA74_25130 73eff81367b7f6cfea30918999e0cba9 252 Gene3D G3DSA:3.40.50.880 1 232 7.9E-51 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_25130 73eff81367b7f6cfea30918999e0cba9 252 SUPERFAMILY SSF52317 4 201 3.7E-39 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_25130 73eff81367b7f6cfea30918999e0cba9 252 Pfam PF00117 Glutamine amidotransferase class-I 22 186 2.1E-18 T 12-10-2018 IPR017926 Glutamine amidotransferase UA74_18005 85ef2461436fcce992a4a2e930aa9fdd 327 Pfam PF04116 Fatty acid hydroxylase superfamily 133 264 2.9E-25 T 12-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 UA74_07570 888c3fec0bef668457609e71e8215802 275 Gene3D G3DSA:3.40.50.880 1 268 1.2E-48 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_07570 888c3fec0bef668457609e71e8215802 275 SUPERFAMILY SSF52317 1 266 1.09E-39 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like UA74_07570 888c3fec0bef668457609e71e8215802 275 Pfam PF17124 ThiJ/PfpI family-like 9 174 2.0E-17 T 12-10-2018 IPR032633 ThiJ/PfpI family-like UA74_28345 ccd789a05678179f94f46ec5a0cc3714 271 Gene3D G3DSA:2.130.10.10 34 246 8.8E-7 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UA74_28345 ccd789a05678179f94f46ec5a0cc3714 271 SUPERFAMILY SSF50969 80 261 8.63E-11 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like UA74_28345 ccd789a05678179f94f46ec5a0cc3714 271 Pfam PF05096 Glutamine cyclotransferase 34 267 5.8E-96 T 12-10-2018 IPR007788 Glutaminyl-peptide cyclotransferase GO:0016603|GO:0017186 MetaCyc: PWY-7942 UA74_16775 4e9b6b7c15d0694b416cca3666fe1f91 252 Pfam PF14436 Bacterial EndoU nuclease 103 199 2.3E-7 T 12-10-2018 IPR029501 Bacterial EndoU nuclease UA74_12850 e16a91d307db99e38bac9c427e90515c 238 Pfam PF12870 Domain of unknown function (DUF4878) 112 199 3.2E-6 T 12-10-2018 IPR024267 Domain of unknown function (DUF4878) UA74_12850 e16a91d307db99e38bac9c427e90515c 238 SUPERFAMILY SSF81995 4 74 1.36E-6 T 12-10-2018 UA74_04340 4df64846e586bfaeea5b700c1dd1e1fd 381 SUPERFAMILY SSF89392 101 265 1.92E-8 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX UA74_04340 4df64846e586bfaeea5b700c1dd1e1fd 381 Gene3D G3DSA:2.50.20.10 80 264 2.5E-17 T 12-10-2018 UA74_24035 d58a05b6394d81cd6e2ab8ca6248f478 228 Pfam PF12079 Protein of unknown function (DUF3558) 39 223 3.5E-23 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_02395 c7d550f3dad9e5195de73781084de512 286 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 20 46 1.7E-6 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 UA74_02395 c7d550f3dad9e5195de73781084de512 286 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 85 265 2.0E-30 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 UA74_15940 ba7ecd4832f796ad96910cc70d078852 589 Gene3D G3DSA:1.10.150.130 55 162 6.7E-20 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal UA74_15940 ba7ecd4832f796ad96910cc70d078852 589 SUPERFAMILY SSF56349 60 367 6.73E-46 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UA74_15940 ba7ecd4832f796ad96910cc70d078852 589 Gene3D G3DSA:1.10.443.10 177 373 7.2E-32 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UA74_15940 ba7ecd4832f796ad96910cc70d078852 589 Pfam PF00589 Phage integrase family 171 360 9.1E-15 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UA74_02020 1cc82a197183cd89ffbdeccf3607b359 118 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 110 2.5E-19 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_02020 1cc82a197183cd89ffbdeccf3607b359 118 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 115 15.548 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UA74_30115 6a7fe7aa9326637692a70fdc5f931898 383 Pfam PF01594 AI-2E family transporter 3 328 5.3E-64 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like UA74_22155 7479bab8c12ee07497e4eafdc15034b6 261 Gene3D G3DSA:3.20.20.150 2 246 9.6E-43 T 12-10-2018 UA74_22155 7479bab8c12ee07497e4eafdc15034b6 261 Pfam PF01261 Xylose isomerase-like TIM barrel 78 211 1.5E-18 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_22155 7479bab8c12ee07497e4eafdc15034b6 261 SUPERFAMILY SSF51658 11 221 1.43E-27 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_12860 d1abe6ea3e14e3bea9b199230b8d0d6d 177 Pfam PF12079 Protein of unknown function (DUF3558) 20 176 1.5E-10 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_13145 1e1749666bc6875cda7bec6e50d2a605 196 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 7 165 8.9E-58 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain UA74_13145 1e1749666bc6875cda7bec6e50d2a605 196 Pfam PF13298 DNA polymerase Ligase (LigD) 36 147 6.2E-39 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain UA74_15040 05e73d37654650f1cdfff49822724066 391 Gene3D G3DSA:3.40.630.30 22 217 4.8E-12 T 12-10-2018 UA74_24145 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 1.5E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_24145 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 1.5E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_24145 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 1.5E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_24145 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 1.5E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_24145 cac9372dd8033ac558dfa92900805faf 296 Gene3D G3DSA:3.40.50.1820 7 290 1.5E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24145 cac9372dd8033ac558dfa92900805faf 296 SUPERFAMILY SSF53474 4 285 1.63E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_24145 cac9372dd8033ac558dfa92900805faf 296 Pfam PF00561 alpha/beta hydrolase fold 30 269 2.9E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_24145 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00412 Epoxide hydrolase signature 38 56 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_24145 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00412 Epoxide hydrolase signature 115 128 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_24145 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00412 Epoxide hydrolase signature 261 283 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_24145 cac9372dd8033ac558dfa92900805faf 296 PRINTS PR00412 Epoxide hydrolase signature 228 244 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UA74_18440 143458b0cdab699ee391a8acf66a5391 360 SUPERFAMILY SSF53098 139 281 9.61E-10 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily UA74_18440 143458b0cdab699ee391a8acf66a5391 360 Gene3D G3DSA:3.30.420.10 138 290 5.0E-11 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UA74_05755 127e94e865d6762d326ddfc3fd82d650 181 Gene3D G3DSA:3.90.470.20 48 170 1.9E-12 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UA74_13865 d0c2b132a0ab0f14c8e11dc3af87576d 340 Pfam PF09084 NMT1/THI5 like 50 255 7.8E-42 T 12-10-2018 IPR015168 SsuA/THI5-like UA74_13865 d0c2b132a0ab0f14c8e11dc3af87576d 340 Gene3D G3DSA:3.40.190.10 41 315 2.4E-65 T 12-10-2018 UA74_13865 d0c2b132a0ab0f14c8e11dc3af87576d 340 Gene3D G3DSA:3.40.190.10 120 223 2.4E-65 T 12-10-2018 UA74_13865 d0c2b132a0ab0f14c8e11dc3af87576d 340 SUPERFAMILY SSF53850 38 262 1.72E-34 T 12-10-2018 UA74_11065 701f8a617b9d7a8122298b45cef3cfe3 180 SUPERFAMILY SSF54593 51 179 1.29E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_11065 701f8a617b9d7a8122298b45cef3cfe3 180 Gene3D G3DSA:3.10.180.10 50 180 1.0E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_16175 9aa21a21d8ccc3d5828e052144ecfed8 596 SUPERFAMILY SSF53300 427 580 2.78E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UA74_21040 0f39ed16595afed469dcd81806735600 280 Gene3D G3DSA:3.20.20.150 4 241 6.9E-27 T 12-10-2018 UA74_21040 0f39ed16595afed469dcd81806735600 280 Pfam PF01261 Xylose isomerase-like TIM barrel 29 202 5.4E-17 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UA74_21040 0f39ed16595afed469dcd81806735600 280 SUPERFAMILY SSF51658 24 217 6.77E-23 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily UA74_15375 84f80664fa108d45a8d0a156cf08c8fb 352 SUPERFAMILY SSF51735 6 349 1.6E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily UA74_15375 84f80664fa108d45a8d0a156cf08c8fb 352 Gene3D G3DSA:3.40.50.720 1 352 1.0E-109 T 12-10-2018 UA74_15375 84f80664fa108d45a8d0a156cf08c8fb 352 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 103 2.3E-8 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UA74_24260 c976b824075f299f2ffd05c3e4205ae3 405 Pfam PF04235 Protein of unknown function (DUF418) 232 394 5.5E-39 T 12-10-2018 IPR007349 Domain of unknown function DUF418 UA74_16205 b5e26bf2833bcc0751b72468eeb49395 152 SUPERFAMILY SSF46785 10 104 1.53E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_16205 b5e26bf2833bcc0751b72468eeb49395 152 Gene3D G3DSA:1.10.10.10 2 82 2.3E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 158 174 3.1E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 339 354 3.1E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 175 190 3.1E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 311 338 3.1E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 294 305 3.1E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 111 122 3.1E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 360 369 3.1E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 PRINTS PR00359 B-class P450 signature 369 380 3.1E-37 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 Pfam PF00067 Cytochrome P450 198 389 2.1E-12 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 SUPERFAMILY SSF48264 18 420 5.76E-77 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 Gene3D G3DSA:1.10.630.10 17 420 1.4E-98 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UA74_17480 7c5dfa4b21636af145589c4204e4b3c2 420 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 362 371 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UA74_04560 11fb0e668915f5ccd523c3f652fdc814 424 SUPERFAMILY SSF103473 7 397 1.12E-51 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_04560 11fb0e668915f5ccd523c3f652fdc814 424 Gene3D G3DSA:1.20.1250.20 5 393 9.0E-45 T 12-10-2018 UA74_04560 11fb0e668915f5ccd523c3f652fdc814 424 Pfam PF07690 Major Facilitator Superfamily 250 402 1.3E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_04560 11fb0e668915f5ccd523c3f652fdc814 424 Pfam PF07690 Major Facilitator Superfamily 19 249 1.5E-24 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UA74_04500 70a491944642053a4b8280c831c64ce1 195 Pfam PF12079 Protein of unknown function (DUF3558) 19 186 4.0E-18 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_22525 1e3f5b58c1b50a387a2868e611cf663a 382 Gene3D G3DSA:3.40.50.150 15 251 1.4E-48 T 12-10-2018 UA74_22525 1e3f5b58c1b50a387a2868e611cf663a 382 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 167 182 - T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 UA74_22525 1e3f5b58c1b50a387a2868e611cf663a 382 SUPERFAMILY SSF53335 82 209 8.02E-22 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_22525 1e3f5b58c1b50a387a2868e611cf663a 382 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 73 211 1.9E-26 T 12-10-2018 UA74_19945 037b2bb58505b0ae18839df04ffb5557 446 Pfam PF01757 Acyltransferase family 98 421 2.0E-27 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_13660 94833cf0714d05ff324e09c6907e6f59 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.1E-5 T 12-10-2018 UA74_13660 94833cf0714d05ff324e09c6907e6f59 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 1.1E-5 T 12-10-2018 UA74_13660 94833cf0714d05ff324e09c6907e6f59 413 Gene3D G3DSA:3.50.50.60 4 324 4.2E-133 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_13660 94833cf0714d05ff324e09c6907e6f59 413 Gene3D G3DSA:3.30.9.40 65 273 4.2E-133 T 12-10-2018 UA74_13660 94833cf0714d05ff324e09c6907e6f59 413 SUPERFAMILY SSF51905 2 357 1.42E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_00365 46472d9c69f3994b837517b63c00b326 372 Pfam PF01757 Acyltransferase family 17 336 2.0E-19 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_29040 c1bebe024800aead0121277e692d87e3 415 Gene3D G3DSA:1.20.1250.20 13 400 1.6E-33 T 12-10-2018 UA74_29040 c1bebe024800aead0121277e692d87e3 415 Pfam PF05977 Transmembrane secretion effector 11 396 7.3E-39 T 12-10-2018 IPR010290 Transmembrane secretion effector UA74_29040 c1bebe024800aead0121277e692d87e3 415 SUPERFAMILY SSF103473 17 405 4.19E-38 T 12-10-2018 IPR036259 MFS transporter superfamily UA74_29735 bda12f00a88577f54ecf3d902c3ae54a 338 Gene3D G3DSA:3.40.50.1980 75 197 6.4E-34 T 12-10-2018 UA74_29735 bda12f00a88577f54ecf3d902c3ae54a 338 Pfam PF01497 Periplasmic binding protein 85 310 1.1E-32 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain UA74_29735 bda12f00a88577f54ecf3d902c3ae54a 338 Gene3D G3DSA:3.40.50.1980 198 337 5.6E-43 T 12-10-2018 UA74_29735 bda12f00a88577f54ecf3d902c3ae54a 338 SUPERFAMILY SSF53807 83 334 1.33E-41 T 12-10-2018 UA74_19880 65099a495028774995cb98689ef030f5 1126 Pfam PF13569 Domain of unknown function (DUF4132) 853 1035 4.4E-55 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 UA74_01410 eebd03cb6fdefc5feea976a1b28375e5 123 Pfam PF14029 Protein of unknown function (DUF4244) 68 120 2.4E-23 T 12-10-2018 IPR025338 Protein of unknown function DUF4244 UA74_11835 74b4b82e3f049305be4ae3d4a7650525 168 Gene3D G3DSA:1.10.260.40 86 154 4.5E-30 T 12-10-2018 UA74_11835 74b4b82e3f049305be4ae3d4a7650525 168 Pfam PF13560 Helix-turn-helix domain 94 153 1.2E-9 T 12-10-2018 UA74_11835 74b4b82e3f049305be4ae3d4a7650525 168 SUPERFAMILY SSF47413 92 152 1.27E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_11835 74b4b82e3f049305be4ae3d4a7650525 168 SMART SM00530 98 152 2.3E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UA74_21320 8c5b850a42a071c697cedfa2493ca869 192 Pfam PF04892 VanZ like family 81 149 3.0E-7 T 12-10-2018 IPR006976 VanZ-like UA74_00835 f5024f7145a9de390a9ab15247c6a6ca 225 SUPERFAMILY SSF159275 30 225 2.62E-41 T 12-10-2018 UA74_00835 f5024f7145a9de390a9ab15247c6a6ca 225 Pfam PF06475 Putative glycolipid-binding 32 224 1.8E-43 T 12-10-2018 IPR009467 Putative glycolipid-binding protein UA74_17495 2e307a41fb596459d94f963c488e56fc 137 SUPERFAMILY SSF54593 6 133 4.83E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_17495 2e307a41fb596459d94f963c488e56fc 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 129 5.5E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_17495 2e307a41fb596459d94f963c488e56fc 137 Gene3D G3DSA:3.10.180.10 3 132 6.6E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_24665 52900cf52f67b7b62d1f93e844169212 225 Pfam PF11353 Protein of unknown function (DUF3153) 126 212 1.9E-8 T 12-10-2018 IPR021499 Protein of unknown function DUF3153 UA74_01355 fb8306167af3d74bd72f7125558c8ff5 457 SUPERFAMILY SSF140459 32 179 8.37E-7 T 12-10-2018 UA74_24390 fea657a0c38a004e35d7b995773e9cf5 132 Gene3D G3DSA:3.30.70.100 1 107 6.8E-8 T 12-10-2018 UA74_24390 fea657a0c38a004e35d7b995773e9cf5 132 SUPERFAMILY SSF54909 4 68 3.09E-7 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_12320 111f53ae155800225cc4fb31ce3237dd 156 Pfam PF10756 Bacterial PH domain 76 146 3.0E-20 T 12-10-2018 IPR019692 Protein of unknown function DUF2581 UA74_10415 16e3bbe467d0d515ebd178bf37925094 356 SUPERFAMILY SSF53756 4 338 2.04E-66 T 12-10-2018 UA74_10415 16e3bbe467d0d515ebd178bf37925094 356 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 75 316 2.6E-23 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 UA74_10415 16e3bbe467d0d515ebd178bf37925094 356 Gene3D G3DSA:3.40.50.2000 171 341 6.2E-41 T 12-10-2018 UA74_10415 16e3bbe467d0d515ebd178bf37925094 356 Gene3D G3DSA:3.40.50.2000 4 154 6.2E-8 T 12-10-2018 UA74_18710 503fecbf05f3c2cc8c40acbcce9e7374 324 SUPERFAMILY SSF51556 33 248 4.23E-25 T 12-10-2018 IPR032466 Metal-dependent hydrolase UA74_18710 503fecbf05f3c2cc8c40acbcce9e7374 324 Gene3D G3DSA:3.20.20.140 21 248 1.9E-24 T 12-10-2018 UA74_18710 503fecbf05f3c2cc8c40acbcce9e7374 324 Pfam PF04909 Amidohydrolase 191 248 1.9E-6 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UA74_30190 ccefa5d47cea3c8dc48f41140d5bd11d 70 Gene3D G3DSA:1.10.150.20 14 69 1.5E-6 T 12-10-2018 UA74_11210 7c4e10b6efd3787dfa04f671cc52a7fe 59 Pfam PF04149 Domain of unknown function (DUF397) 6 55 3.0E-20 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_12930 0e902c547ec263e3145967b3d2fd14f8 70 Gene3D G3DSA:2.30.30.990 1 53 7.4E-6 T 12-10-2018 UA74_12930 0e902c547ec263e3145967b3d2fd14f8 70 Pfam PF16827 zinc-finger 4 58 1.6E-8 T 12-10-2018 IPR031795 Putative zinc-finger containing protein UA74_00650 79a331bfa79ee45a1d399cb9bc591154 122 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 2 106 1.4E-23 T 12-10-2018 IPR019277 Protein of unknown function DUF2304 UA74_20090 a752a5a69762bf936a88ea4ef47f8a7b 130 Gene3D G3DSA:3.30.720.120 8 53 5.6E-8 T 12-10-2018 UA74_20090 a752a5a69762bf936a88ea4ef47f8a7b 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 120 1.2E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UA74_20090 a752a5a69762bf936a88ea4ef47f8a7b 130 Gene3D G3DSA:3.30.720.110 70 123 3.7E-19 T 12-10-2018 UA74_20090 a752a5a69762bf936a88ea4ef47f8a7b 130 SUPERFAMILY SSF54593 7 123 2.15E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UA74_01585 e9092a38837c4f42debfab30ae61c89c 609 Pfam PF13367 Protease prsW family 54 249 9.3E-52 T 12-10-2018 IPR026898 Protease PrsW GO:0008233 UA74_11975 5d953bbb1cda96e94d44b3cbd36c76d7 149 Pfam PF07681 DoxX 12 94 1.0E-19 T 12-10-2018 IPR032808 DoxX family UA74_20230 302188a43473550878d3f43f9bdc5b23 398 SUPERFAMILY SSF46785 268 397 7.88E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_20230 302188a43473550878d3f43f9bdc5b23 398 Gene3D G3DSA:1.10.10.10 263 398 1.3E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_18375 a6288301191296a2e447d92a5c32419d 456 Pfam PF12770 CHAT domain 124 383 7.4E-7 T 12-10-2018 IPR024983 CHAT domain UA74_08385 1e97f0fddaef8168286ee720e437a9ae 87 Pfam PF11238 Protein of unknown function (DUF3039) 26 81 6.7E-28 T 12-10-2018 IPR021400 Protein of unknown function DUF3039 UA74_26790 ea78b8235dcb77b626e28080bba52b05 159 Pfam PF04138 GtrA-like protein 2 132 2.1E-22 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 UA74_16400 e735806941bad03e0451e5821a675461 433 Gene3D G3DSA:3.40.710.10 59 408 7.9E-88 T 12-10-2018 UA74_16400 e735806941bad03e0451e5821a675461 433 Pfam PF00144 Beta-lactamase 103 406 4.2E-54 T 12-10-2018 IPR001466 Beta-lactamase-related UA74_16400 e735806941bad03e0451e5821a675461 433 SUPERFAMILY SSF56601 61 402 1.13E-66 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UA74_06205 e0b455f07853cffad7c9b474fdcaef23 187 Pfam PF09438 Domain of unknown function (DUF2017) 6 184 1.0E-59 T 12-10-2018 IPR018561 Domain of unknown function DUF2017 UA74_12515 43af2e803f52ee9367e7ee437a689cd7 361 Pfam PF01022 Bacterial regulatory protein, arsR family 125 157 7.4E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UA74_12515 43af2e803f52ee9367e7ee437a689cd7 361 Gene3D G3DSA:1.10.10.10 103 230 3.1E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UA74_12515 43af2e803f52ee9367e7ee437a689cd7 361 SUPERFAMILY SSF46785 116 301 5.01E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UA74_19560 1dcce80afcdd66b56a48d91d2625d7ff 158 Pfam PF03995 Peptidase inhibitor family I36 55 128 1.7E-7 T 12-10-2018 UA74_16230 70094c4051c109e0f8d8c9a63a67aec2 349 Pfam PF13814 Replication-relaxation 44 227 4.3E-50 T 12-10-2018 IPR025855 Plasmid replication-relaxation UA74_19710 c8bce06a5c125252cef4c132ad6e4898 148 PRINTS PR00502 NUDIX hydrolase family signature 48 62 2.3E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_19710 c8bce06a5c125252cef4c132ad6e4898 148 PRINTS PR00502 NUDIX hydrolase family signature 62 77 2.3E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UA74_19710 c8bce06a5c125252cef4c132ad6e4898 148 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UA74_19710 c8bce06a5c125252cef4c132ad6e4898 148 Gene3D G3DSA:3.90.79.10 19 145 6.7E-25 T 12-10-2018 UA74_19710 c8bce06a5c125252cef4c132ad6e4898 148 Pfam PF00293 NUDIX domain 22 124 8.4E-16 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UA74_19710 c8bce06a5c125252cef4c132ad6e4898 148 SUPERFAMILY SSF55811 23 127 2.71E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_29955 a9baccc8dd22166bf5ce4e506ebfda50 170 Pfam PF06803 Protein of unknown function (DUF1232) 93 127 1.2E-13 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 UA74_20870 45fff93c9873ea80b67ea976d4a85a9f 62 Pfam PF04149 Domain of unknown function (DUF397) 7 57 2.7E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_27180 7c39a259b4196ba9abc4885d91855a7a 206 Pfam PF01899 Na+/H+ ion antiporter subunit 19 162 3.9E-26 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 UA74_01230 e699c4a9a2ca915295f3e4079797010d 292 SUPERFAMILY SSF55811 19 226 7.04E-15 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UA74_01230 e699c4a9a2ca915295f3e4079797010d 292 Gene3D G3DSA:3.90.79.10 22 255 2.1E-68 T 12-10-2018 UA74_10355 591c552f68ca7dc6ffef6f7015ac606c 430 Gene3D G3DSA:1.25.40.10 195 278 1.3E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_10355 591c552f68ca7dc6ffef6f7015ac606c 430 SMART SM00028 382 415 190.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_10355 591c552f68ca7dc6ffef6f7015ac606c 430 SMART SM00028 302 335 42.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_10355 591c552f68ca7dc6ffef6f7015ac606c 430 SMART SM00028 215 248 40.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_10355 591c552f68ca7dc6ffef6f7015ac606c 430 SMART SM00028 342 375 23.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UA74_10355 591c552f68ca7dc6ffef6f7015ac606c 430 Gene3D G3DSA:1.25.40.10 279 414 1.2E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_10355 591c552f68ca7dc6ffef6f7015ac606c 430 SUPERFAMILY SSF48452 208 412 7.11E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_04675 8d7cec6638bdf446ade69f3f53dc72e6 189 Pfam PF03703 Bacterial PH domain 81 137 8.2E-12 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_04735 3eebae877346abdf798d14d6984d045d 298 Pfam PF11350 Protein of unknown function (DUF3152) 89 298 1.7E-63 T 12-10-2018 IPR022603 Domain of unknown function DUF3152 UA74_04735 3eebae877346abdf798d14d6984d045d 298 SUPERFAMILY SSF55486 167 275 2.4E-11 T 12-10-2018 UA74_05580 9d88b46783122f04774650fe5df5421b 272 SUPERFAMILY SSF56112 95 238 1.0E-6 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_27205 bcc6da6c1b66a7fb834f838668bb0bbe 530 Gene3D G3DSA:3.20.20.240 3 530 5.2E-231 T 12-10-2018 UA74_27205 bcc6da6c1b66a7fb834f838668bb0bbe 530 SUPERFAMILY SSF51703 9 524 2.88E-201 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_27205 bcc6da6c1b66a7fb834f838668bb0bbe 530 Pfam PF01642 Methylmalonyl-CoA mutase 9 522 5.2E-218 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_27205 bcc6da6c1b66a7fb834f838668bb0bbe 530 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 9 526 3.6E-229 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 UA74_09030 504d48192128d7cd74f9db81408427c6 121 Pfam PF11255 Protein of unknown function (DUF3054) 12 112 3.5E-25 T 12-10-2018 IPR021414 Protein of unknown function DUF3054 UA74_17225 bfa4b7fd386f8445f67b1bba80b67254 421 SUPERFAMILY SSF69318 79 371 1.88E-7 T 12-10-2018 UA74_23610 38bf5c50bebdc89b45f82b23206153dc 264 Pfam PF04248 Domain of unknown function (DUF427) 41 131 7.6E-29 T 12-10-2018 IPR007361 Domain of unknown function DUF427 UA74_23610 38bf5c50bebdc89b45f82b23206153dc 264 Pfam PF04248 Domain of unknown function (DUF427) 164 254 9.3E-28 T 12-10-2018 IPR007361 Domain of unknown function DUF427 UA74_23610 38bf5c50bebdc89b45f82b23206153dc 264 Gene3D G3DSA:2.170.150.40 150 262 2.2E-32 T 12-10-2018 UA74_23610 38bf5c50bebdc89b45f82b23206153dc 264 Gene3D G3DSA:2.170.150.40 27 136 4.0E-32 T 12-10-2018 UA74_09005 a6f1fd49e1e6b8011675ba818c8f8f95 92 Pfam PF04226 Transglycosylase associated protein 33 82 1.7E-13 T 12-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 UA74_25600 43c5caa2e836e457535d8d2758e2c48a 203 Pfam PF02620 Uncharacterized ACR, COG1399 75 185 2.0E-27 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD UA74_28020 365e00859d505df1f1d88f1e9276e797 930 Gene3D G3DSA:1.10.287.1060 180 270 8.8E-6 T 12-10-2018 UA74_28020 365e00859d505df1f1d88f1e9276e797 930 SUPERFAMILY SSF140453 189 266 5.36E-7 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_14100 880b1d2b085eccf415a34db649ed6a0a 238 Pfam PF02698 DUF218 domain 44 166 1.2E-24 T 12-10-2018 IPR003848 Domain of unknown function DUF218 UA74_11995 72608bead5ef792469976146d6c3e4cb 405 SUPERFAMILY SSF56112 40 325 4.52E-21 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily UA74_11995 72608bead5ef792469976146d6c3e4cb 405 Pfam PF01636 Phosphotransferase enzyme family 73 272 5.4E-7 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase UA74_18660 ab7416770fa5da2b8129c7ecc38f9e4f 233 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 27 224 3.2E-28 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UA74_18660 ab7416770fa5da2b8129c7ecc38f9e4f 233 SUPERFAMILY SSF52518 27 227 9.09E-50 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold UA74_18660 ab7416770fa5da2b8129c7ecc38f9e4f 233 Gene3D G3DSA:3.40.50.970 16 231 2.1E-52 T 12-10-2018 UA74_26265 cb13c0913afebdb569e8da49b5240b19 295 Pfam PF12679 ABC-2 family transporter protein 71 294 1.3E-9 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UA74_07245 17daa490cb483fda3b73e516229fa328 487 SUPERFAMILY SSF55486 47 216 1.67E-14 T 12-10-2018 UA74_07245 17daa490cb483fda3b73e516229fa328 487 Pfam PF04228 Putative neutral zinc metallopeptidase 41 209 7.4E-7 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative UA74_18260 606ee5c2dd1452b7bfa4ec3b97e1c9eb 770 Pfam PF13699 Domain of unknown function (DUF4157) 81 152 1.1E-24 T 12-10-2018 IPR025295 Domain of unknown function DUF4157 UA74_29860 3fbf9e080f8f7a7717d2f79f0fc33316 91 Pfam PF11755 Protein of unknown function (DUF3311) 20 70 3.5E-12 T 12-10-2018 IPR021741 Protein of unknown function DUF3311 UA74_13615 6d80ab1b72aa563e598eb16a661de304 341 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 327 9.5E-25 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_06690 c2b927b1d030b14f456cf18137198fad 179 Pfam PF00583 Acetyltransferase (GNAT) family 58 156 2.0E-7 T 12-10-2018 IPR000182 GNAT domain UA74_06690 c2b927b1d030b14f456cf18137198fad 179 SUPERFAMILY SSF55729 13 165 2.79E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_06690 c2b927b1d030b14f456cf18137198fad 179 Gene3D G3DSA:3.40.630.30 9 167 6.4E-25 T 12-10-2018 UA74_23690 dd36dd1226c1425d2ecf8d3ad412d47c 342 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 18 263 1.0E-64 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain UA74_23690 dd36dd1226c1425d2ecf8d3ad412d47c 342 Gene3D G3DSA:3.90.920.30 25 303 7.9E-87 T 12-10-2018 UA74_27240 8af5b1d0911b1ec0f8222cef9684d692 66 SUPERFAMILY SSF47598 2 58 4.18E-6 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 UA74_27240 8af5b1d0911b1ec0f8222cef9684d692 66 Pfam PF01402 Ribbon-helix-helix protein, copG family 2 34 1.1E-5 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 UA74_02070 34a971accde28df56d24cf1dd06a81e8 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 7.2E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_22670 112255aba45eed87cf59dd0151b1ce7d 238 Pfam PF01925 Sulfite exporter TauE/SafE 9 230 1.9E-20 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_20705 27a3d4ee9d3b26efdfb1cbdd950aab36 395 Gene3D G3DSA:3.40.50.2300 201 373 7.6E-23 T 12-10-2018 UA74_20705 27a3d4ee9d3b26efdfb1cbdd950aab36 395 Pfam PF13407 Periplasmic binding protein domain 126 347 8.5E-27 T 12-10-2018 IPR025997 Periplasmic binding protein UA74_20705 27a3d4ee9d3b26efdfb1cbdd950aab36 395 SUPERFAMILY SSF53822 95 369 1.4E-38 T 12-10-2018 IPR028082 Periplasmic binding protein-like I UA74_20705 27a3d4ee9d3b26efdfb1cbdd950aab36 395 Gene3D G3DSA:3.40.50.2300 88 200 4.2E-14 T 12-10-2018 UA74_20010 3bd2d7a1b0ddbd3f15069423d01c2fb2 411 Gene3D G3DSA:3.40.640.10 56 304 1.0E-49 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UA74_20010 3bd2d7a1b0ddbd3f15069423d01c2fb2 411 SUPERFAMILY SSF53383 61 369 9.5E-26 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UA74_10590 e9c0f390dcc04abf4db200448cd9b9eb 586 Pfam PF13699 Domain of unknown function (DUF4157) 86 155 2.5E-24 T 12-10-2018 IPR025295 Domain of unknown function DUF4157 UA74_19105 f5face286ed835146108c2f47b92c05f 1813 SUPERFAMILY SSF53335 326 1267 5.72E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_19105 f5face286ed835146108c2f47b92c05f 1813 Gene3D G3DSA:3.40.50.150 578 752 7.5E-18 T 12-10-2018 UA74_02195 bc5bb74ad2461e84637dde182a3918a3 438 Pfam PF06114 IrrE N-terminal-like domain 249 348 6.6E-17 T 12-10-2018 IPR010359 IrrE N-terminal-like domain UA74_02195 bc5bb74ad2461e84637dde182a3918a3 438 SUPERFAMILY SSF47413 55 113 2.93E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_06680 d4be6963af29a98441aeb69822d5773f 187 Pfam PF03703 Bacterial PH domain 97 170 4.2E-14 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_23510 97f38a253bc557d4c37d89fcf72b53b6 140 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 20 135 7.5E-33 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III UA74_15245 7044bcc1d22871e593ed8efbc93efbc9 305 SUPERFAMILY SSF103481 55 145 6.15E-9 T 12-10-2018 UA74_15245 7044bcc1d22871e593ed8efbc93efbc9 305 Pfam PF00892 EamA-like transporter family 153 285 1.5E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_15245 7044bcc1d22871e593ed8efbc93efbc9 305 Pfam PF00892 EamA-like transporter family 14 142 1.1E-9 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UA74_15245 7044bcc1d22871e593ed8efbc93efbc9 305 SUPERFAMILY SSF103481 188 289 1.7E-14 T 12-10-2018 UA74_05255 9e4faeeaedb89b2521f304a92f009927 221 Gene3D G3DSA:3.40.50.850 10 202 1.2E-42 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_05255 9e4faeeaedb89b2521f304a92f009927 221 Pfam PF00857 Isochorismatase family 18 168 7.5E-27 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 UA74_05255 9e4faeeaedb89b2521f304a92f009927 221 SUPERFAMILY SSF52499 11 192 5.23E-44 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UA74_13960 7d46ff8cfa2ba877b2a427022251e5df 212 Gene3D G3DSA:3.40.960.10 91 211 5.6E-41 T 12-10-2018 UA74_13960 7d46ff8cfa2ba877b2a427022251e5df 212 Pfam PF03852 DNA mismatch endonuclease Vsr 83 143 3.2E-17 T 12-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 UA74_13960 7d46ff8cfa2ba877b2a427022251e5df 212 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 81 190 7.9E-37 T 12-10-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 UA74_13960 7d46ff8cfa2ba877b2a427022251e5df 212 SUPERFAMILY SSF52980 78 201 1.61E-36 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UA74_20815 64b4eb8d0335982bea02ea1d8f69acf0 356 Gene3D G3DSA:2.40.420.20 254 329 2.3E-11 T 12-10-2018 UA74_14635 702d84df00dfafb47da46abee8a407af 271 SUPERFAMILY SSF53474 10 270 3.11E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_14635 702d84df00dfafb47da46abee8a407af 271 Gene3D G3DSA:3.40.50.1820 5 271 2.4E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_14635 702d84df00dfafb47da46abee8a407af 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 1.6E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_14635 702d84df00dfafb47da46abee8a407af 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 215 229 1.6E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_14635 702d84df00dfafb47da46abee8a407af 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.6E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_14635 702d84df00dfafb47da46abee8a407af 271 Pfam PF00561 alpha/beta hydrolase fold 25 258 2.5E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_12095 9776db555a16d23d29236911485a4df5 445 Pfam PF02378 Phosphotransferase system, EIIC 25 336 1.2E-70 T 12-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UA74_10170 e3d0086f461c9819564cced4adeb3756 287 Gene3D G3DSA:3.90.850.10 69 286 2.2E-79 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 UA74_10170 e3d0086f461c9819564cced4adeb3756 287 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 279 1.5E-66 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 UA74_10170 e3d0086f461c9819564cced4adeb3756 287 SUPERFAMILY SSF56529 64 281 1.2E-72 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 UA74_02430 8f78254e82944b96f4afd236ff9afe9e 96 Pfam PF14012 Protein of unknown function (DUF4229) 16 77 3.3E-12 T 12-10-2018 IPR025323 Protein of unknown function DUF4229 UA74_16605 744fa72bc7a6cdc96fd35a955ceb3337 252 Gene3D G3DSA:3.40.50.150 35 192 3.2E-15 T 12-10-2018 UA74_16605 744fa72bc7a6cdc96fd35a955ceb3337 252 SUPERFAMILY SSF53335 8 158 2.07E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_24285 cacb914904958c4353988a9b14f8aecb 246 Pfam PF01061 ABC-2 type transporter 6 212 1.2E-23 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UA74_24285 cacb914904958c4353988a9b14f8aecb 246 PIRSF PIRSF006648 5 245 1.2E-16 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 UA74_16105 e7fb993f16c7fb0d778276a65c536cfb 284 Gene3D G3DSA:3.40.50.300 2 236 1.7E-19 T 12-10-2018 UA74_16105 e7fb993f16c7fb0d778276a65c536cfb 284 SUPERFAMILY SSF52540 2 235 9.11E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_29265 49dc74fbff4170578e8af3185e60fd1f 541 SUPERFAMILY SSF140459 25 171 5.75E-5 T 12-10-2018 UA74_16360 df04ce25b6d947c81d84f1b3f5e8b5f8 143 Pfam PF13276 HTH-like domain 62 117 3.0E-18 T 12-10-2018 IPR025948 HTH-like domain UA74_10375 10bd27ecb2695a28c0865e3d7f5b5da3 112 Gene3D G3DSA:3.40.50.1820 8 108 1.9E-12 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_10375 10bd27ecb2695a28c0865e3d7f5b5da3 112 SUPERFAMILY SSF53474 18 109 6.53E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_20740 01317c2a61451d0f0b1e6c8d5a6d5758 150 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 7 135 4.8E-50 T 12-10-2018 IPR011749 Conserved hypothetical protein CHP02243 UA74_25035 759a97ecb2e9ed3e51b8c795247a3b1c 249 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 249 42.041 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 UA74_25035 759a97ecb2e9ed3e51b8c795247a3b1c 249 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 1 244 9.5E-34 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 UA74_25035 759a97ecb2e9ed3e51b8c795247a3b1c 249 Pfam PF02654 Cobalamin-5-phosphate synthase 8 243 4.0E-46 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 UA74_19150 53e2f0e31593aff6be27568d204f7222 131 Pfam PF01899 Na+/H+ ion antiporter subunit 5 108 9.9E-27 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 UA74_07315 1b07f8da8f7bf8c5137619be64cf167d 303 Pfam PF14100 Methane oxygenase PmoA 22 295 7.1E-65 T 12-10-2018 IPR029475 Methane oxygenase PmoA UA74_13900 213f1e4892d44c7693f648e64b29d79d 270 PIRSF PIRSF017393 3 270 1.5E-80 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_13900 213f1e4892d44c7693f648e64b29d79d 270 SUPERFAMILY SSF53335 23 262 7.88E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_13900 213f1e4892d44c7693f648e64b29d79d 270 Gene3D G3DSA:3.40.50.150 5 269 3.6E-86 T 12-10-2018 UA74_13900 213f1e4892d44c7693f648e64b29d79d 270 Pfam PF04672 S-adenosyl methyltransferase 14 256 9.4E-77 T 12-10-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type UA74_10890 2d71390f60bf3621179dbbafc2241a79 126 Pfam PF04486 SchA/CurD like domain 1 119 4.6E-49 T 12-10-2018 IPR007575 SchA/CurD-like domain UA74_21835 157763d98a36d1a054ac81838cf27e88 294 Pfam PF00561 alpha/beta hydrolase fold 26 150 3.8E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_21835 157763d98a36d1a054ac81838cf27e88 294 Gene3D G3DSA:3.40.50.1820 6 283 2.6E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_21835 157763d98a36d1a054ac81838cf27e88 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_21835 157763d98a36d1a054ac81838cf27e88 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_21835 157763d98a36d1a054ac81838cf27e88 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_21835 157763d98a36d1a054ac81838cf27e88 294 SUPERFAMILY SSF53474 21 258 3.48E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_22140 55e2648db9307057414e93ac63e01072 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 326 2.1E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_22140 55e2648db9307057414e93ac63e01072 330 Gene3D G3DSA:1.10.3720.10 92 322 2.7E-14 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22140 55e2648db9307057414e93ac63e01072 330 SUPERFAMILY SSF161098 98 314 1.09E-11 T 12-10-2018 IPR035906 MetI-like superfamily UA74_10805 90b7ecab820ac7c81bf7c5d02337f331 81 SUPERFAMILY SSF47598 4 58 1.22E-8 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 UA74_29020 2d9ea4448d3b988ae255ef1262edb275 399 Gene3D G3DSA:1.25.40.10 144 286 1.7E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_29020 2d9ea4448d3b988ae255ef1262edb275 399 SUPERFAMILY SSF48452 177 285 4.01E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_16120 383231774eae2e81e3b7e1a2ce95a944 297 Pfam PF00482 Type II secretion system (T2SS), protein F 161 288 4.0E-9 T 12-10-2018 IPR018076 Type II secretion system F domain UA74_10035 abbdd7781ca4a9bf9c8c3c6c45eb121e 248 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 69 244 1.1E-30 T 12-10-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp UA74_08495 f6dfba8316990d6f0a694fa0a1cfc237 669 Pfam PF13520 Amino acid permease 57 458 1.8E-24 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UA74_13410 d4da8b8f8f2bb1230e68dfd6625d778a 384 SUPERFAMILY SSF53335 82 199 5.79E-31 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UA74_13410 d4da8b8f8f2bb1230e68dfd6625d778a 384 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 79 200 1.2E-28 T 12-10-2018 UA74_08640 68fbe7b79bdd51559bc81e83915b3ee8 174 Gene3D G3DSA:3.10.350.10 116 167 4.6E-7 T 12-10-2018 IPR036779 LysM domain superfamily UA74_08640 68fbe7b79bdd51559bc81e83915b3ee8 174 Pfam PF01476 LysM domain 119 166 3.7E-4 T 12-10-2018 IPR018392 LysM domain UA74_22845 08ff72fc30d09d8584f12b3bc01fecfa 273 Pfam PF03756 A-factor biosynthesis hotdog domain 102 234 9.1E-21 T 12-10-2018 IPR005509 A-factor biosynthesis hotdog domain UA74_08415 f15b72cdb3fed14713a2e369ad9e2a7f 479 Pfam PF02653 Branched-chain amino acid transport system / permease component 77 463 4.5E-30 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_08365 9a423e5854d3db35546bc29b10e3aab2 115 Pfam PF11298 Protein of unknown function (DUF3099) 21 89 5.3E-28 T 12-10-2018 IPR021449 Protein of unknown function DUF3099 UA74_18310 db45cd5b82134ee9887f1f145e13d426 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 322 8.3E-45 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_23020 3548b8c97e40d90becc75fd52c5f8d03 64 Pfam PF04149 Domain of unknown function (DUF397) 11 62 2.0E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_14590 e93ad37e8f0cbbac189dea923be6a5e0 507 Pfam PF01554 MatE 304 458 8.2E-10 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UA74_07865 c1c51a8870baa631a9705fb0214814e2 1786 Gene3D G3DSA:1.25.40.10 147 375 2.8E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UA74_03115 ead23e4ae4accbc12c89becb9c9e2dca 187 Pfam PF08044 Domain of unknown function (DUF1707) 19 71 1.4E-22 T 12-10-2018 IPR012551 Protein of unknown function DUF1707 UA74_03790 38d78f587f6ac1a0bee2f7d209e7434c 483 Pfam PF01882 Protein of unknown function DUF58 235 339 1.4E-16 T 12-10-2018 IPR002881 Domain of unknown function DUF58 UA74_03720 3fe549d0fb68a58d391b43cd17fe9568 322 Pfam PF13406 Transglycosylase SLT domain 236 279 5.4E-8 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 UA74_03720 3fe549d0fb68a58d391b43cd17fe9568 322 SUPERFAMILY SSF53955 151 317 4.16E-34 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_20540 3d2c7dad9d4c01ed9fc51f8c6087eaed 749 Pfam PF03235 Protein of unknown function DUF262 4 208 2.7E-25 T 12-10-2018 IPR004919 Domain of unknown function DUF262 UA74_10670 89aa86bbb55de6e391602bb642069e82 698 Pfam PF01757 Acyltransferase family 40 371 7.2E-20 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_10300 de3b616dea0202b61aa1a4fefcf3cc99 284 Gene3D G3DSA:2.70.70.10 28 155 7.7E-34 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_10300 de3b616dea0202b61aa1a4fefcf3cc99 284 SUPERFAMILY SSF51261 55 150 9.42E-30 T 12-10-2018 IPR011055 Duplicated hybrid motif UA74_10300 de3b616dea0202b61aa1a4fefcf3cc99 284 Pfam PF01551 Peptidase family M23 55 150 2.3E-25 T 12-10-2018 IPR016047 Peptidase M23 UA74_27725 24786af8ebcebadcb1202f04e90cd2a9 73 TIGRFAM TIGR04186 GRASP_targ: putative ATP-grasp target RiPP 6 70 2.0E-8 T 12-10-2018 IPR026496 Putative ATP-grasp target RiPP UA74_29645 a03fa698257013519c3fdc5bd15d4db7 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 2.8E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_24875 c6dcd73fd0663d5d3561f954498d5dd5 372 SUPERFAMILY SSF53756 2 370 1.57E-76 T 12-10-2018 UA74_24875 c6dcd73fd0663d5d3561f954498d5dd5 372 Gene3D G3DSA:3.40.50.2000 166 359 7.3E-124 T 12-10-2018 UA74_24875 c6dcd73fd0663d5d3561f954498d5dd5 372 Pfam PF00534 Glycosyl transferases group 1 179 352 2.4E-42 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 UA74_24875 c6dcd73fd0663d5d3561f954498d5dd5 372 Gene3D G3DSA:3.40.50.2000 1 165 7.3E-124 T 12-10-2018 UA74_24875 c6dcd73fd0663d5d3561f954498d5dd5 372 Pfam PF13439 Glycosyltransferase Family 4 9 168 7.4E-13 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UA74_15340 a6cc0e76cfef70522b13b7a180762b01 138 SUPERFAMILY SSF88946 5 68 3.81E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UA74_15340 a6cc0e76cfef70522b13b7a180762b01 138 Gene3D G3DSA:1.10.1740.10 2 70 7.0E-7 T 12-10-2018 UA74_15340 a6cc0e76cfef70522b13b7a180762b01 138 Pfam PF04542 Sigma-70 region 2 6 70 4.3E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UA74_24735 dd71ad0f03046053fc11515ec4865f61 948 Pfam PF03639 Glycosyl hydrolase family 81 57 689 1.8E-63 T 12-10-2018 IPR005200 Endo-1,3(4)-beta-glucanase GO:0052861 UA74_19420 337280d60a7b3c1db7a941f600e08797 287 Pfam PF13569 Domain of unknown function (DUF4132) 27 207 1.5E-30 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 UA74_26050 d61ed28c2b248629d7c178315caee81d 251 SUPERFAMILY SSF55021 37 102 2.91E-6 T 12-10-2018 UA74_24030 96ba390938e12c9eab96be1eda067a72 462 SUPERFAMILY SSF140459 41 180 3.92E-6 T 12-10-2018 UA74_05460 4e1f2a4e375a5b4fd2605a9d2a790dbb 107 Gene3D G3DSA:1.10.287.1060 2 102 7.3E-9 T 12-10-2018 UA74_05460 4e1f2a4e375a5b4fd2605a9d2a790dbb 107 SUPERFAMILY SSF140453 5 98 6.15E-5 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_26155 6b340ca3f63dab823253f9e651d230bd 231 Pfam PF12079 Protein of unknown function (DUF3558) 31 222 7.8E-9 T 12-10-2018 IPR024520 Protein of unknown function DUF3558 UA74_02170 937d7d80a05f06bcddb1e20686f7d076 170 Pfam PF10698 Protein of unknown function (DUF2505) 14 162 8.6E-36 T 12-10-2018 IPR019639 Protein of unknown function DUF2505 UA74_10835 1f5c2e38554532cf9d20a81b2e92c4d0 165 Pfam PF14081 Domain of unknown function (DUF4262) 16 138 1.2E-37 T 12-10-2018 IPR025358 Protein of unknown function DUF4262 UA74_30200 48514c16e66de9b694f7b28374fda6a8 169 Pfam PF13630 SdpI/YhfL protein family 64 128 2.5E-10 T 12-10-2018 IPR025962 SdpI/YhfL protein family UA74_28450 70d67e8efbe5a4af9a5691a9dfb8d201 763 Pfam PF13625 Helicase conserved C-terminal domain 468 590 1.3E-39 T 12-10-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 UA74_03710 5be8dd31cdb11a4b056d80588d0665df 281 Pfam PF13406 Transglycosylase SLT domain 193 237 9.0E-8 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 UA74_03710 5be8dd31cdb11a4b056d80588d0665df 281 SUPERFAMILY SSF53955 104 270 1.97E-35 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily UA74_10255 25c7e377ff0328402943a1c1d3549631 142 Gene3D G3DSA:3.30.70.1060 1 117 2.0E-36 T 12-10-2018 UA74_10255 25c7e377ff0328402943a1c1d3549631 142 SUPERFAMILY SSF54909 1 118 7.51E-36 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel UA74_10255 25c7e377ff0328402943a1c1d3549631 142 Pfam PF03795 YCII-related domain 1 114 8.4E-25 T 12-10-2018 IPR005545 YCII-related UA74_01150 cfde996ad4d8ce5bb760a6f738365041 500 SUPERFAMILY SSF53474 58 470 8.03E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold UA74_01150 cfde996ad4d8ce5bb760a6f738365041 500 Pfam PF00561 alpha/beta hydrolase fold 81 472 1.4E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UA74_22490 9e529f3e503201d3d8d58ddfea06a2b4 297 SUPERFAMILY SSF161098 90 277 1.03E-21 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22490 9e529f3e503201d3d8d58ddfea06a2b4 297 Gene3D G3DSA:1.10.3720.10 86 290 1.8E-18 T 12-10-2018 IPR035906 MetI-like superfamily UA74_22490 9e529f3e503201d3d8d58ddfea06a2b4 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 296 3.3E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UA74_08305 24cdad2f58921c7a37c0aace412fc3b5 268 Pfam PF01925 Sulfite exporter TauE/SafE 22 259 4.5E-35 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 UA74_28975 1db1cf31cf5fd9b5b079df01abc2078c 104 Pfam PF12728 Helix-turn-helix domain 25 73 8.8E-11 T 12-10-2018 UA74_28975 1db1cf31cf5fd9b5b079df01abc2078c 104 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 25 72 4.5E-9 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 UA74_10960 ef0d5ffe1342e6a55a62d4f7aea0cc6b 129 Pfam PF04486 SchA/CurD like domain 1 119 4.0E-49 T 12-10-2018 IPR007575 SchA/CurD-like domain UA74_21400 23ceced77c75cb41b7c3a493247a817d 326 SUPERFAMILY SSF56281 52 290 4.98E-38 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_21400 23ceced77c75cb41b7c3a493247a817d 326 Gene3D G3DSA:3.60.15.10 58 319 5.4E-80 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UA74_21400 23ceced77c75cb41b7c3a493247a817d 326 Pfam PF12706 Beta-lactamase superfamily domain 85 275 5.5E-48 T 12-10-2018 IPR001279 Metallo-beta-lactamase UA74_21400 23ceced77c75cb41b7c3a493247a817d 326 PIRSF PIRSF038896 42 320 6.0E-101 T 12-10-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 UA74_12670 f476a5112148fd1d269cce166585b64f 199 Gene3D G3DSA:1.10.357.10 6 180 1.8E-39 T 12-10-2018 UA74_12670 f476a5112148fd1d269cce166585b64f 199 SUPERFAMILY SSF46689 2 74 3.59E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_13425 4f00692a3cabe1522988c1773443f483 296 Pfam PF03747 ADP-ribosylglycohydrolase 12 270 4.0E-47 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 UA74_13425 4f00692a3cabe1522988c1773443f483 296 Gene3D G3DSA:1.10.4080.10 5 290 3.5E-59 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily UA74_13425 4f00692a3cabe1522988c1773443f483 296 SUPERFAMILY SSF101478 3 271 8.24E-53 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily UA74_18475 a0b5359de15f07fbc4cb533f4d6b1b30 62 Pfam PF04149 Domain of unknown function (DUF397) 6 57 2.2E-18 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_04800 dbe0fa72a628f86cb2c11be6513482ba 371 Pfam PF04228 Putative neutral zinc metallopeptidase 174 362 1.7E-18 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative UA74_12400 64f2bb2a4ae42088d63edc09729060a2 406 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 52 297 8.3E-88 T 12-10-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA UA74_12400 64f2bb2a4ae42088d63edc09729060a2 406 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 2 304 1.4E-79 T 12-10-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA UA74_26850 60a464265ac1d39f269ce4da116a3de6 178 Pfam PF03703 Bacterial PH domain 78 149 2.5E-18 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_17605 db92c05275a54e489287bdde38c751d9 467 Pfam PF00890 FAD binding domain 74 199 5.1E-5 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UA74_17605 db92c05275a54e489287bdde38c751d9 467 SUPERFAMILY SSF51905 8 378 1.36E-23 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_17605 db92c05275a54e489287bdde38c751d9 467 Gene3D G3DSA:3.50.50.60 8 415 2.7E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UA74_04250 acdc6029a9474d83127b809ce5f783e1 648 Pfam PF02687 FtsX-like permease family 549 639 3.5E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_04250 acdc6029a9474d83127b809ce5f783e1 648 Pfam PF02687 FtsX-like permease family 89 179 1.4E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_26870 bfc1589ca77e61a7d923fd245ec8cd46 74 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 12 69 3.4E-20 T 12-10-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit UA74_26205 a2f36cfbe43e3c2359823fa1128cfbf7 134 SUPERFAMILY SSF54913 31 131 1.07E-34 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta UA74_26205 a2f36cfbe43e3c2359823fa1128cfbf7 134 Gene3D G3DSA:3.30.70.120 20 131 1.1E-36 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UA74_26205 a2f36cfbe43e3c2359823fa1128cfbf7 134 Pfam PF03091 CutA1 divalent ion tolerance protein 33 129 1.5E-33 T 12-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 UA74_13390 01806b3c3ffd0d6e3443c09f93b1f896 71 Pfam PF04149 Domain of unknown function (DUF397) 6 63 5.4E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_10615 8a12609d2e90632a1418d706e9266e74 381 Pfam PF02653 Branched-chain amino acid transport system / permease component 65 334 1.3E-47 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_26070 84fa6e99b2bf641a00dd0f62f4e1e61f 76 Gene3D G3DSA:3.40.50.1010 1 75 8.0E-15 T 12-10-2018 UA74_26070 84fa6e99b2bf641a00dd0f62f4e1e61f 76 SUPERFAMILY SSF88723 4 65 1.85E-8 T 12-10-2018 IPR029060 PIN-like domain superfamily UA74_07830 2366d1fd09f35bac8dc2aeaa0810d89c 156 Pfam PF00487 Fatty acid desaturase 11 126 3.2E-19 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 UA74_11705 42b14c4ab1feb5492ed0d9bd617630ce 303 Pfam PF03741 Integral membrane protein TerC family 15 201 5.0E-47 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 UA74_24775 c063a8d6a50337ad078f85f93d084a85 581 Gene3D G3DSA:1.10.287.1060 78 169 1.3E-6 T 12-10-2018 UA74_24775 c063a8d6a50337ad078f85f93d084a85 581 SUPERFAMILY SSF140453 82 170 9.81E-8 T 12-10-2018 IPR036689 ESAT-6-like superfamily UA74_22275 32960a31ff5da611406c122951c18dd9 442 Gene3D G3DSA:3.40.190.10 158 429 3.0E-46 T 12-10-2018 UA74_22275 32960a31ff5da611406c122951c18dd9 442 Pfam PF13416 Bacterial extracellular solute-binding protein 74 371 2.4E-22 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein UA74_22275 32960a31ff5da611406c122951c18dd9 442 Gene3D G3DSA:3.40.190.10 89 369 3.0E-46 T 12-10-2018 UA74_22275 32960a31ff5da611406c122951c18dd9 442 SUPERFAMILY SSF53850 89 432 2.05E-42 T 12-10-2018 UA74_13670 6f190eb0c70c742d848b0cd724d6f151 118 Pfam PF05331 Protein of unknown function (DUF742) 7 116 1.5E-29 T 12-10-2018 IPR007995 Protein of unknown function DUF742 UA74_09710 8b2955be6ed03b67bff7f9740d70a545 94 Pfam PF02325 YGGT family 10 91 1.7E-13 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 UA74_12610 e7813988e2169f06621aed8672bdbd33 239 Gene3D G3DSA:3.30.420.60 96 217 8.3E-14 T 12-10-2018 UA74_12610 e7813988e2169f06621aed8672bdbd33 239 SUPERFAMILY SSF53137 95 222 5.36E-21 T 12-10-2018 UA74_11280 d6b8efa24aec35897da92a04fafecd9f 340 Pfam PF00950 ABC 3 transport family 16 272 2.8E-54 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UA74_11280 d6b8efa24aec35897da92a04fafecd9f 340 SUPERFAMILY SSF81345 19 265 4.05E-22 T 12-10-2018 IPR037294 ABC transporter, BtuC-like UA74_24290 1539c04bd873c2137c50e363d0d25aed 302 Pfam PF00005 ABC transporter 20 157 1.8E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UA74_24290 1539c04bd873c2137c50e363d0d25aed 302 Gene3D G3DSA:3.40.50.300 1 228 1.3E-61 T 12-10-2018 UA74_24290 1539c04bd873c2137c50e363d0d25aed 302 SUPERFAMILY SSF52540 3 236 3.25E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_24290 1539c04bd873c2137c50e363d0d25aed 302 SMART SM00382 28 205 2.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain UA74_24290 1539c04bd873c2137c50e363d0d25aed 302 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UA74_12555 7cccb046668c905fdad961b63c5c043e 69 Pfam PF04149 Domain of unknown function (DUF397) 10 61 1.1E-14 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_19890 e14fefc9f42664ee493bda172ebc8890 1183 Pfam PF13569 Domain of unknown function (DUF4132) 889 1096 1.8E-45 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 UA74_24620 9b40bc5d910ca532a7c369d4df0e0227 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 5.3E-30 T 12-10-2018 IPR021408 Protein of unknown function DUF3046 UA74_04585 c1d4b563bc76b0ee6a92bc6027b3f745 289 Pfam PF13490 Putative zinc-finger 15 45 2.7E-5 T 12-10-2018 IPR027383 Putative zinc-finger UA74_06720 e7f2e485962383997bd8f7ef34e55872 166 Gene3D G3DSA:3.40.630.30 5 149 8.7E-21 T 12-10-2018 UA74_06720 e7f2e485962383997bd8f7ef34e55872 166 Pfam PF00583 Acetyltransferase (GNAT) family 59 129 6.5E-11 T 12-10-2018 IPR000182 GNAT domain UA74_06720 e7f2e485962383997bd8f7ef34e55872 166 SUPERFAMILY SSF55729 6 136 4.9E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase UA74_00040 757e050446ed33dcb2ae145f79ae86a4 361 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 245 359 3.2E-44 T 12-10-2018 IPR021949 Domain of unknown function DUF3566. transmembrane UA74_28970 43eba8497b9ebc091c4fa28f041742ba 131 Gene3D G3DSA:1.10.260.40 7 70 3.7E-5 T 12-10-2018 UA74_22580 94abbf2a80b3885d3b1763d1488359bf 68 Pfam PF04149 Domain of unknown function (DUF397) 10 63 1.3E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_18650 9f8695d820e8a3ad45edd1098d474351 83 Gene3D G3DSA:3.30.10.20 8 77 3.9E-6 T 12-10-2018 UA74_02435 db454c4d2f15b27e91b16544d8dcb004 110 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 96 5.1E-5 T 12-10-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 UA74_28875 90af348d589cc1fabed2d38835ab5d38 129 Pfam PF12986 Domain of unknown function (DUF3870) 24 112 1.4E-21 T 12-10-2018 IPR024617 Domain of unknown function DUF3870 UA74_25225 5fc66ab185af3cf4b1e39c94555e6823 991 Pfam PF12846 AAA-like domain 500 885 1.3E-21 T 12-10-2018 UA74_25225 5fc66ab185af3cf4b1e39c94555e6823 991 SUPERFAMILY SSF52540 474 836 2.02E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UA74_17165 fac2d21840b03a5df99600e403c151b1 248 Pfam PF13490 Putative zinc-finger 3 37 1.5E-4 T 12-10-2018 IPR027383 Putative zinc-finger UA74_01860 6aff81b529c6fffd47580c801bee0e96 318 Pfam PF11361 Protein of unknown function (DUF3159) 28 212 4.7E-51 T 12-10-2018 IPR016566 Uncharacterised conserved protein UCP010219 UA74_06545 8605490f12564f1bf9a489807c21449d 284 Gene3D G3DSA:1.10.260.40 10 84 2.3E-7 T 12-10-2018 UA74_06545 8605490f12564f1bf9a489807c21449d 284 SUPERFAMILY SSF47413 10 69 1.04E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UA74_06545 8605490f12564f1bf9a489807c21449d 284 Pfam PF13560 Helix-turn-helix domain 13 75 3.7E-11 T 12-10-2018 UA74_21460 c16dc35650e0069a0f7e5398ca964807 352 Pfam PF02616 Segregation and condensation protein ScpA 107 327 1.3E-60 T 12-10-2018 IPR003768 Segregation and condensation protein A UA74_21215 fe8695a508ba3b13012da350c8415743 256 Pfam PF07103 Protein of unknown function (DUF1365) 20 246 3.6E-58 T 12-10-2018 IPR010775 Protein of unknown function DUF1365 UA74_09565 75ee5b989e648d5c0a9543d89d347975 422 Pfam PF00860 Permease family 31 386 4.9E-74 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 UA74_03680 5c6a8887656b159b0990b8e0687286dc 315 Pfam PF13624 SurA N-terminal domain 10 114 1.5E-6 T 12-10-2018 UA74_03680 5c6a8887656b159b0990b8e0687286dc 315 Gene3D G3DSA:1.10.4030.30 34 190 1.4E-6 T 12-10-2018 UA74_03680 5c6a8887656b159b0990b8e0687286dc 315 SUPERFAMILY SSF109998 35 154 1.44E-7 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily UA74_17780 1630dddfe42e013d32dbcd6ede5ff86e 273 Pfam PF13471 Transglutaminase-like superfamily 138 239 3.5E-20 T 12-10-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal UA74_22960 13826cf1c4e9a84bb07a634d463037fd 125 Pfam PF05331 Protein of unknown function (DUF742) 13 125 7.2E-29 T 12-10-2018 IPR007995 Protein of unknown function DUF742 UA74_08860 1728e01a1a63305258f4ce6824d99d82 108 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 2.7E-53 T 12-10-2018 IPR019592 Protein of unknown function DUF2469 UA74_09465 9d58bd86631d38673a3ff427dd5f394e 402 Pfam PF06224 Winged helix DNA-binding domain 34 380 1.4E-77 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 UA74_03385 45f64f0da3dc85c9de84654643a790fd 174 Gene3D G3DSA:1.10.1040.10 42 170 5.4E-36 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UA74_09590 0d656a8dbf40aee1f7399bea549e22e4 425 Pfam PF01882 Protein of unknown function DUF58 197 280 2.8E-20 T 12-10-2018 IPR002881 Domain of unknown function DUF58 UA74_25970 1c4d3ca9b589113b88c612d27ebc9f7d 67 Pfam PF04149 Domain of unknown function (DUF397) 13 65 1.8E-20 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_09815 a5e1a1881663e81c142aafacb8ebf618 258 Pfam PF10821 Protein of unknown function (DUF2567) 110 203 5.4E-9 T 12-10-2018 IPR021213 Protein of unknown function DUF2567 UA74_26750 f94b2a108077f4ffcb4775e6aae06ad9 204 Pfam PF13707 RloB-like protein 25 161 2.5E-29 T 12-10-2018 IPR025591 RloB-like protein UA74_04685 e81b51797a5c60f91ec7c81ec84f0d09 275 Pfam PF12705 PD-(D/E)XK nuclease superfamily 15 257 5.4E-30 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type UA74_23265 dd2834cd9e089973f1c7209a6530ef92 122 Pfam PF13788 Domain of unknown function (DUF4180) 9 118 6.1E-40 T 12-10-2018 IPR025438 Domain of unknown function DUF4180 UA74_14305 8520b80763289fedd113cd48e8321ac9 309 Pfam PF03547 Membrane transport protein 13 146 1.4E-7 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 UA74_14305 8520b80763289fedd113cd48e8321ac9 309 Pfam PF03547 Membrane transport protein 163 303 9.0E-10 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 UA74_10815 422876c90f3c14deb853becf27cdafed 302 Pfam PF03591 AzlC protein 20 155 3.0E-33 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease UA74_21010 2bfdb547075ed215277a57c06e32d06f 257 Pfam PF13349 Putative adhesin 121 252 1.5E-12 T 12-10-2018 IPR025164 Putative adhesin UA74_00480 b88dfe8b1aed345e72330e098af9628e 269 Pfam PF14011 EspG family 10 259 8.5E-48 T 12-10-2018 IPR025734 EspG family UA74_11690 a0e6a27651f5471b5bd8840daf2ebe4e 209 Gene3D G3DSA:3.40.50.300 42 196 4.9E-11 T 12-10-2018 UA74_27235 e67c3c73d5e10a49a761d05bc11493cd 131 Gene3D G3DSA:1.20.120.1870 4 127 6.2E-16 T 12-10-2018 UA74_00975 4b6c4a21fd8853c7d4124bcd9d076146 468 Pfam PF01566 Natural resistance-associated macrophage protein 57 399 3.3E-18 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UA74_04525 fd517653988e351d6944750987fca859 259 Pfam PF14011 EspG family 14 253 6.0E-50 T 12-10-2018 IPR025734 EspG family UA74_27120 86ed784b1c62ecdf7838ad367aff3782 195 Gene3D G3DSA:1.10.357.10 2 191 5.5E-28 T 12-10-2018 UA74_27120 86ed784b1c62ecdf7838ad367aff3782 195 SUPERFAMILY SSF46689 6 78 1.3E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UA74_27120 86ed784b1c62ecdf7838ad367aff3782 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 5.5E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UA74_05105 9dc84e452dcdb07fb6c370c42925d650 133 Gene3D G3DSA:3.10.450.50 2 132 1.0E-9 T 12-10-2018 UA74_05105 9dc84e452dcdb07fb6c370c42925d650 133 SUPERFAMILY SSF54427 15 132 4.13E-9 T 12-10-2018 IPR032710 NTF2-like domain superfamily UA74_02040 3eff05e40d9743cb01e40f14ed49287e 102 Pfam PF10724 Protein of unknown function (DUF2516) 9 99 2.5E-29 T 12-10-2018 IPR019662 Protein of unknown function DUF2516 UA74_10345 a0fb3b24bef47f7ada1743c527f1b6e3 107 Pfam PF13453 Transcription factor zinc-finger 1 32 3.4E-12 T 12-10-2018 IPR027392 Transcription factor zinc-finger UA74_29175 b54055343639e4b444efa3f71ed37356 323 Pfam PF06089 L-asparaginase II 6 310 6.3E-112 T 12-10-2018 IPR010349 L-asparaginase II UA74_02770 a3b7e86e1e979633bb847e30d508a915 169 Pfam PF08592 Domain of unknown function (DUF1772) 22 158 4.5E-17 T 12-10-2018 UA74_22810 fa925a38d09e2e33ec47fee18f40cb90 81 Pfam PF04149 Domain of unknown function (DUF397) 18 73 3.7E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_00995 77051d6af5bcff114074c864b83f144a 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 63 328 1.3E-48 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_09525 f3f6316b33bf33b1b5a5a9f1f343d349 104 Pfam PF13707 RloB-like protein 23 101 4.4E-11 T 12-10-2018 IPR025591 RloB-like protein UA74_04665 487b356ddff6c21d74c53dd82fb66b6c 371 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 10 368 2.5E-91 T 12-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 UA74_23505 b9c172e8f9e972758d3be156f58bd631 144 Pfam PF12277 Protein of unknown function (DUF3618) 38 69 3.9E-9 T 12-10-2018 IPR022062 Protein of unknown function DUF3618 UA74_09755 2d5276c220eb77447a0cd8e80b0a3a58 182 Pfam PF03703 Bacterial PH domain 92 151 1.9E-15 T 12-10-2018 IPR005182 Domain of unknown function DUF304 UA74_07270 3f51a4fc6986dfc2a7c1eaedb4ff19c4 470 Pfam PF01757 Acyltransferase family 27 341 3.4E-15 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UA74_21270 a9abc974dbc404f887800943b724e267 290 Pfam PF09335 SNARE associated Golgi protein 46 163 5.8E-20 T 12-10-2018 IPR032816 SNARE associated Golgi protein UA74_11480 0d98a2a29bd000e599b4cff7da76841d 490 SUPERFAMILY SSF81995 10 87 9.15E-6 T 12-10-2018 UA74_19370 0e0050d3a0bd5feb218137cd4836557a 283 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 246 267 1.2E-7 T 12-10-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 UA74_23500 069bf03ff27fbb15cdc353c05ce0c289 95 Pfam PF14019 Protein of unknown function (DUF4235) 7 83 4.3E-25 T 12-10-2018 IPR025329 Protein of unknown function DUF4235 UA74_29275 9ee223e5b1bf8162020e262b83a47f6b 266 Pfam PF14011 EspG family 20 257 3.2E-51 T 12-10-2018 IPR025734 EspG family UA74_11715 d2826c40b5ede55af0293646172bafbc 239 Gene3D G3DSA:3.30.565.10 17 135 2.5E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_26735 da10b34961179157d14d1875a9f879ba 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 67 335 6.0E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UA74_01405 2a8f83fbcf89184d24d146c2e9d8ef1b 239 Pfam PF00482 Type II secretion system (T2SS), protein F 104 221 8.6E-14 T 12-10-2018 IPR018076 Type II secretion system F domain UA74_18470 09d2c81f77732fe297357883487454ae 63 Pfam PF04149 Domain of unknown function (DUF397) 7 58 2.6E-17 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_03400 9c1b3cf249abef4061391944ad5f842d 407 Pfam PF04235 Protein of unknown function (DUF418) 240 405 1.7E-29 T 12-10-2018 IPR007349 Domain of unknown function DUF418 UA74_18195 209d422691110f694c3a320affb21208 284 Pfam PF01040 UbiA prenyltransferase family 31 257 3.0E-20 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 UA74_17760 52f9a287c013973c2600c518f1b2c118 65 Pfam PF04149 Domain of unknown function (DUF397) 9 60 4.2E-16 T 12-10-2018 IPR007278 Domain of unknown function DUF397 UA74_08715 b236da35140b76288a115a164c3bc0a5 368 Pfam PF13830 Domain of unknown function (DUF4192) 30 342 5.0E-76 T 12-10-2018 IPR025447 Protein of unknown function DUF4192 UA74_00420 3524cb49760e345f6be1dd04c4e8e1bc 116 Pfam PF04341 Protein of unknown function, DUF485 22 109 1.5E-35 T 12-10-2018 IPR007436 Protein of unknown function DUF485 UA74_23965 074d3c4f02322f2e2cdf3f535c48835d 353 Pfam PF04235 Protein of unknown function (DUF418) 197 329 1.4E-28 T 12-10-2018 IPR007349 Domain of unknown function DUF418 UA74_00230 d0637741c899bb31fdad4d34d1bac8ec 338 Pfam PF05425 Copper resistance protein D 237 335 8.0E-19 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 UA74_25755 5a86f6551373c6d6a64698bec6143de2 190 Pfam PF12028 Protein of unknown function (DUF3515) 22 185 1.1E-47 T 12-10-2018 IPR021903 Protein of unknown function DUF3515 UA74_12010 f8a54ead79d237a099e6dd63168bc795 259 Pfam PF05988 Bacterial protein of unknown function (DUF899) 13 197 2.1E-19 T 12-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like UA74_16130 f70b55f85fbd076da6d589013fd1aec8 127 Pfam PF07811 TadE-like protein 1 39 1.8E-7 T 12-10-2018 IPR012495 TadE-like UA74_04545 4a4dd401185b4c1d4fecfe1d457362f8 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 52 2.4E-29 T 12-10-2018 IPR021465 Protein of unknown function DUF3117 UA74_05560 1d4a6c4db769aee87b1e701cac13d482 218 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 84 215 4.0E-19 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 UA74_03260 1478adf7e3174e42920c4ff0d4f285f8 219 SMART SM00858 58 120 4.4E-7 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UA74_00510 54c1afa96b562b6b30d8c876d22fe628 204 Pfam PF10517 Electron transfer DM13 99 201 1.7E-24 T 12-10-2018 IPR019545 DM13 domain UA74_28220 bce1cf6770630dfbc56aa8bb41080d30 406 Pfam PF12698 ABC-2 family transporter protein 33 382 2.6E-45 T 12-10-2018 UA74_26055 3e6bc74a0b27fd0c5acbccd52d8e04e0 392 Pfam PF03235 Protein of unknown function DUF262 58 129 4.0E-14 T 12-10-2018 IPR004919 Domain of unknown function DUF262 UA74_20565 19e98c7fad357c15c396371ae4f4f043 630 Pfam PF09369 Domain of unknown function (DUF1998) 494 596 4.8E-9 T 12-10-2018 IPR018973 DEAD/DEAH-box helicase, putative UA74_28335 9786917f2f40f0b3fee6c9165a9d005d 1034 SUPERFAMILY SSF55874 53 142 4.52E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UA74_18105 9dd125a2501f3e83255a4c3ce46c9fea 255 Pfam PF12730 ABC-2 family transporter protein 5 176 3.0E-21 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UA74_01570 c3f955ca3dc7e05d19b17472fe2846cc 161 Pfam PF11377 Protein of unknown function (DUF3180) 9 143 2.9E-34 T 12-10-2018 IPR021517 Protein of unknown function DUF3180 UA74_03160 f2ce62c7a0bfcecc15b5ebb702892be6 557 Pfam PF05960 Bacterial protein of unknown function (DUF885) 20 546 6.5E-154 T 12-10-2018 IPR010281 Protein of unknown function DUF885 UA74_20805 2eaccbe0158b154b0b34dbab823b77aa 435 Pfam PF02687 FtsX-like permease family 336 427 3.4E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UA74_09580 51ebef95ab602bb3846bf37695952831 137 Pfam PF11239 Protein of unknown function (DUF3040) 1 85 9.1E-30 T 12-10-2018 IPR021401 Protein of unknown function DUF3040 UA74_29970 1b7326a46d14c6eba48f49e085076ed4 176 Pfam PF17249 Family of unknown function (DUF5318) 43 171 2.5E-69 T 12-10-2018 IPR035169 Protein of unknown function DUF5318 UA74_11115 b43b10c1e0069242c69ad0919e8216db 629 Pfam PF07907 YibE/F-like protein 204 442 2.9E-71 T 12-10-2018 IPR012507 YibE/F-like UA74_14905 ecad227bfb8e682b1b4903501ee3fe32 190 Pfam PF04434 SWIM zinc finger 125 144 2.2E-4 T 12-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 UA74_08795 c36f367f94beb0df2cf95b455f4ebccc 717 Pfam PF03235 Protein of unknown function DUF262 14 232 1.0E-27 T 12-10-2018 IPR004919 Domain of unknown function DUF262 UA74_01110 721caa1f55943aa60065758d1524e075 67 Gene3D G3DSA:2.10.230.20 14 65 4.8E-5 T 12-10-2018 UA74_23655 703fce8476f54cb165c487050144b6ee 168 Pfam PF03780 Asp23 family, cell envelope-related function 105 159 7.2E-7 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 UA74_05940 316ecf0c5d59738b493a62f19c1416aa 166 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 160 6.2E-59 T 12-10-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger