locus-tag	class	description
ACEE_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACEE_00010	COG0592	DNA-directed DNA polymerase activity
ACEE_00025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACEE_00035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACEE_00040	COG0616	signal peptide processing
ACEE_00050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACEE_00055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACEE_00060	COG0494	nUDIX hydrolase
ACEE_00065	COG1218	3'(2'),5'-bisphosphate nucleotidase
ACEE_00070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACEE_00075	COG0363	glucosamine-6-phosphate deaminase activity
ACEE_00080	COG2814	Major facilitator Superfamily
ACEE_00085	COG1794	racemase activity, acting on amino acids and derivatives
ACEE_00090	COG3594	Acyltransferase
ACEE_00095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACEE_00110	COG3115	cell septum assembly
ACEE_00115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACEE_00130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACEE_00165	COG2814	Major facilitator Superfamily
ACEE_00195	COG1090	epimerase
ACEE_00200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACEE_00205	COG1127	ABC transporter
ACEE_00210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACEE_00215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACEE_00220	COG2854	intermembrane phospholipid transfer
ACEE_00230	COG5007	Belongs to the BolA IbaG family
ACEE_00235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACEE_00250	COG0488	(ABC) transporter
ACEE_00275	COG2166	iron-sulfur cluster assembly
ACEE_00280	COG0740	serine-type endopeptidase activity
ACEE_00285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACEE_00290	COG1663	tetraacyldisaccharide 4'-kinase activity
ACEE_00295	COG2835	tetraacyldisaccharide 4'-kinase activity
ACEE_00335	COG3063	Type IV pilus biogenesis stability protein PilW
ACEE_00340	COG2183	response to ionizing radiation
ACEE_00345	COG1252	NADH dehydrogenase
ACEE_00355	COG3719	Belongs to the RNase T2 family
ACEE_00360	COG0616	signal peptide processing
ACEE_00365	COG0778	Nitroreductase
ACEE_00370	COG0300	oxidoreductase activity
ACEE_00380	COG2217	Heavy metal translocating P-type atpase
ACEE_00385	COG0789	Transcriptional regulator
ACEE_00415	COG0745	RESPONSE REGULATOR receiver
ACEE_00420	COG5002	protein histidine kinase activity
ACEE_00425	COG0187	DNA topoisomerase II activity
ACEE_00430	COG0471	metal ion transport
ACEE_00435	COG0471	metal ion transport
ACEE_00440	COG0471	metal ion transport
ACEE_00445	COG0126	phosphoglycerate kinase activity
ACEE_00450	COG0191	fructose-bisphosphate aldolase activity
ACEE_00455	COG4172	Belongs to the ABC transporter superfamily
ACEE_00470	COG0778	Nitroreductase
ACEE_00480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACEE_00490	COG0084	hydrolase, TatD family'
ACEE_00495	COG1966	Carbon starvation protein
ACEE_00500	COG1640	4-alpha-glucanotransferase
ACEE_00505	COG3833	ABC-type maltose transport systems, permease component
ACEE_00520	COG3842	ATPase activity
ACEE_00525	COG4580	involved in the transport of maltose and maltodextrins
ACEE_00535	COG2909	trisaccharide binding
ACEE_00540	COG0058	SHG alpha-glucan phosphorylase activity
ACEE_00555	COG0560	Phosphoserine phosphatase
ACEE_00565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACEE_00570	COG2081	HI0933 family
ACEE_00575	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACEE_00580	COG2252	PERMEase
ACEE_00585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACEE_00590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACEE_00600	COG0716	FMN binding
ACEE_00605	COG0735	belongs to the Fur family
ACEE_00610	COG3008	intermembrane lipid transfer
ACEE_00615	COG1854	S-ribosylhomocysteine lyase activity
ACEE_00620	COG1132	(ABC) transporter
ACEE_00625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACEE_00635	COG3318	Belongs to the UPF0149 family
ACEE_00635	COG3012	SEC-C Motif Domain Protein
ACEE_00640	COG0673	inositol 2-dehydrogenase activity
ACEE_00645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACEE_00660	COG1426	Protein conserved in bacteria
ACEE_00665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACEE_00675	COG2976	Protein conserved in bacteria
ACEE_00680	COG3201	nicotinamide mononucleotide transporter
ACEE_00695	COG2965	DNA replication, synthesis of RNA primer
ACEE_00710	COG2841	Protein conserved in bacteria
ACEE_00715	COG2268	Band 7 protein
ACEE_00720	COG1609	Transcriptional regulator
ACEE_00725	COG2226	methyltransferase
ACEE_00735	COG0512	Glutamine amidotransferase of anthranilate synthase
ACEE_00740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACEE_00745	COG2837	iron assimilation
ACEE_00750	COG0009	L-threonylcarbamoyladenylate synthase
ACEE_00755	COG1187	pseudouridine synthase activity
ACEE_00765	COG0583	DNA-binding transcription factor activity
ACEE_00800	COG0612	Peptidase, M16
ACEE_00805	COG4178	(ABC) transporter
ACEE_00810	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACEE_00820	COG0217	transcriptional regulatory protein
ACEE_00825	COG0494	nUDIX hydrolase
ACEE_00845	COG0402	S-adenosylhomocysteine deaminase activity
ACEE_00850	COG4143	(ABC) transporter
ACEE_00855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACEE_00860	COG0617	tRNA 3'-terminal CCA addition
ACEE_00865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACEE_00875	COG2911	Protein conserved in bacteria
ACEE_00885	COG0346	lactoylglutathione lyase activity
ACEE_00890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACEE_00900	COG0477	Major facilitator Superfamily
ACEE_00910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACEE_00920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACEE_00920	COG0475	glutathione-regulated potassium exporter activity
ACEE_00925	COG1138	Cytochrome C-type biogenesis protein
ACEE_00930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACEE_00935	COG4235	cytochrome complex assembly
ACEE_00935	COG3088	subunit of a heme lyase
ACEE_00940	COG4235	cytochrome complex assembly
ACEE_00950	COG0748	coenzyme F420 binding
ACEE_00955	COG4771	TonB-dependent receptor
ACEE_00955	COG1629	transport
ACEE_00960	COG0077	Prephenate dehydratase
ACEE_00960	COG1605	Chorismate mutase
ACEE_00965	COG0339	signal peptide processing
ACEE_00975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ACEE_00980	COG1882	Formate acetyltransferase
ACEE_00985	COG2116	formate transmembrane transporter activity
ACEE_00990	COG1238	metal cluster binding
ACEE_00995	COG0501	Belongs to the peptidase M48B family
ACEE_01005	COG2431	L-lysine efflux transmembrane transporter activity
ACEE_01015	COG0436	Aminotransferase
ACEE_01025	COG2962	Rard protein
ACEE_01030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACEE_01035	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ACEE_01045	COG2089	acid synthase
ACEE_01070	COG3306	glycosyltransferase involved in LPS biosynthesis
ACEE_01080	COG1216	Glycosyl transferase, family 2
ACEE_01085	COG1216	Glycosyl transferase, family 2
ACEE_01090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACEE_01090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACEE_01100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACEE_01110	COG0813	purine-nucleoside phosphorylase activity
ACEE_01115	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACEE_01125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACEE_01135	COG4771	TonB-dependent receptor
ACEE_01135	COG1629	transport
ACEE_01140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACEE_01145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACEE_01150	COG0083	homoserine kinase activity
ACEE_01155	COG0527	aspartate kinase activity
ACEE_01155	COG0460	homoserine dehydrogenase
ACEE_01170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACEE_01175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACEE_01205	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACEE_01210	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ACEE_01215	COG0194	GDP metabolic process
ACEE_01220	COG1538	Outer membrane efflux protein
ACEE_01225	COG2914	Belongs to the UPF0125 (RnfH) family
ACEE_01230	COG2867	negative regulation of translational initiation
ACEE_01235	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACEE_01240	COG4149	molybdate abc transporter
ACEE_01245	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACEE_01250	COG0842	Transport permease protein
ACEE_01255	COG1131	(ABC) transporter
ACEE_01260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACEE_01265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACEE_01275	COG0251	oxidation-reduction process
ACEE_01280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACEE_01285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACEE_01290	COG1121	(ABC) transporter
ACEE_01300	COG2920	part of a sulfur-relay system
ACEE_01305	COG0670	Belongs to the BI1 family
ACEE_01310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACEE_01335	COG3118	belongs to the thioredoxin family
ACEE_01340	COG0330	HflC and HflK could
ACEE_01345	COG0330	HflC and HflK could
ACEE_01355	COG0301	tRNA thio-modification
ACEE_01355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACEE_01360	COG1902	pentaerythritol trinitrate reductase activity
ACEE_01375	COG1373	ATPase (AAA superfamily
ACEE_01410	COG0424	maF-like protein
ACEE_01415	COG2252	PERMEase
ACEE_01420	COG1528	Iron-storage protein
ACEE_01425	COG1528	Iron-storage protein
ACEE_01430	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACEE_01435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACEE_01445	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ACEE_01455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACEE_01475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACEE_01480	COG1454	alcohol dehydrogenase
ACEE_01480	COG1012	belongs to the aldehyde dehydrogenase family
ACEE_01485	COG0181	hydroxymethylbilane synthase activity
ACEE_01490	COG1587	Uroporphyrinogen-III synthase
ACEE_01495	COG2959	enzyme of heme biosynthesis
ACEE_01500	COG3071	HemY protein
ACEE_01505	COG2354	Protein conserved in bacteria
ACEE_01510	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACEE_01520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACEE_01525	COG2095	MarC family integral membrane protein
ACEE_01530	COG4166	transmembrane transport
ACEE_01535	COG0489	protein tyrosine kinase activity
ACEE_01595	COG2017	converts alpha-aldose to the beta-anomer
ACEE_01600	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACEE_01605	COG1085	galactose-1-phosphate uridylyltransferase
ACEE_01615	COG0642	Histidine kinase
ACEE_01620	COG0745	RESPONSE REGULATOR receiver
ACEE_01630	COG3111	PFAM Bacterial OB fold (BOF) protein
ACEE_01645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACEE_01700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACEE_01705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACEE_01710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACEE_01725	COG1253	flavin adenine dinucleotide binding
ACEE_01730	COG0564	pseudouridine synthase activity
ACEE_01735	COG0588	phosphoglycerate mutase activity
ACEE_01740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACEE_01745	COG1678	Uncharacterized ACR, COG1678
ACEE_01750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACEE_01760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACEE_01765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACEE_01770	COG1408	metallophosphoesterase
ACEE_01775	COG0753	catalase activity
ACEE_01785	COG0626	cystathionine gamma-synthase activity
ACEE_01790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ACEE_01805	COG1702	phosphate starvation-inducible protein PhoH
ACEE_01810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACEE_01815	COG0254	rRNA binding
ACEE_01825	COG0583	DNA-binding transcription factor activity
ACEE_01830	COG0708	Exodeoxyribonuclease III
ACEE_01835	COG2056	Na+-H+ antiporter family
ACEE_01845	COG0037	tRNA processing
ACEE_01850	COG3092	negative regulation of chromosome organization
ACEE_01865	COG1607	acyl-coa hydrolase
ACEE_01870	COG2350	Protein conserved in bacteria
ACEE_01885	COG0786	glutamate:sodium symporter activity
ACEE_01905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACEE_01910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ACEE_01915	COG2831	hemolysin activation secretion protein
ACEE_01920	COG3210	domain, Protein
ACEE_01955	COG0138	bifunctional purine biosynthesis protein purh
ACEE_01965	COG2027	D-alanyl-D-alanine carboxypeptidase
ACEE_01970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACEE_01980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACEE_01985	COG0156	8-amino-7-oxononanoate synthase activity
ACEE_01990	COG2830	Protein of unknown function (DUF452)
ACEE_01995	COG2226	methyltransferase
ACEE_02000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACEE_02005	COG2840	Smr protein MutS2
ACEE_02010	COG0697	spore germination
ACEE_02015	COG0784	Response regulator, receiver
ACEE_02015	COG2198	Histidine kinase
ACEE_02015	COG5002	protein histidine kinase activity
ACEE_02020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACEE_02030	COG1959	2 iron, 2 sulfur cluster binding
ACEE_02035	COG1104	cysteine desulfurase activity
ACEE_02040	COG0822	iron-sulfur transferase activity
ACEE_02050	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACEE_02070	COG0633	Ferredoxin
ACEE_02075	COG2975	iron-sulfur cluster assembly
ACEE_02085	COG0617	tRNA 3'-terminal CCA addition
ACEE_02090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACEE_02095	COG0215	cysteine-tRNA ligase activity
ACEE_02100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACEE_02125	COG0583	DNA-binding transcription factor activity
ACEE_02135	COG0110	maltose O-acetyltransferase activity
ACEE_02145	COG3642	lipopolysaccharide core region biosynthetic process
ACEE_02150	COG0302	gtp cyclohydrolase
ACEE_02160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACEE_02165	COG1560	Kdo2-lipid A biosynthetic process
ACEE_02170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACEE_02180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACEE_02195	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACEE_02205	COG1704	LemA family
ACEE_02210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACEE_02210	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ACEE_02210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACEE_02215	COG1105	Belongs to the carbohydrate kinase PfkB family
ACEE_02220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACEE_02220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACEE_02230	COG1523	belongs to the glycosyl hydrolase 13 family
ACEE_02240	COG0297	glycogen (starch) synthase activity
ACEE_02245	COG0058	SHG alpha-glucan phosphorylase activity
ACEE_02250	COG0105	UTP biosynthetic process
ACEE_02265	COG1441	menaquinone biosynthetic process
ACEE_02275	COG2814	Major facilitator Superfamily
ACEE_02285	COG3381	protein complex oligomerization
ACEE_02295	COG0791	NLP P60 protein
ACEE_02300	COG2932	Transcriptional regulator
ACEE_02305	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ACEE_02310	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACEE_02320	COG1643	Atp-dependent helicase
ACEE_02325	COG2707	UPF0756 membrane protein
ACEE_02330	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACEE_02335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACEE_02340	COG0534	Mate efflux family protein
ACEE_02345	COG1074	ATP-dependent DNA helicase activity
ACEE_02350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACEE_02355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ACEE_02360	COG1328	CTP reductase activity
ACEE_02365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACEE_02380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACEE_02385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACEE_02395	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACEE_02400	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACEE_02415	COG0750	zinc metalloprotease
ACEE_02420	COG0575	Belongs to the CDS family
ACEE_02425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACEE_02430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACEE_02440	COG0671	phosphoesterase, PA-phosphatase related
ACEE_02445	COG1534	Rna-binding protein
ACEE_02450	COG0463	Glycosyl transferase, family 2
ACEE_02455	COG1686	Belongs to the peptidase S11 family
ACEE_02460	COG0859	PFAM glycosyl transferase family 9
ACEE_02470	COG0328	RNA-DNA hybrid ribonuclease activity
ACEE_02475	COG1286	toxin biosynthetic process
ACEE_02490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACEE_02495	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACEE_02505	COG0251	oxidation-reduction process
ACEE_02520	COG0582	viral genome integration into host DNA
ACEE_02590	COG5645	(Lipo)protein
ACEE_02605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACEE_02615	COG1792	Involved in formation and maintenance of cell shape
ACEE_02620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACEE_02625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACEE_02630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACEE_02635	COG0121	glutamine amidotransferase
ACEE_02650	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACEE_02655	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACEE_02660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACEE_02665	COG0045	succinate-CoA ligase (ADP-forming) activity
ACEE_02670	COG2990	Protein conserved in bacteria
ACEE_02675	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACEE_02680	COG0567	Dehydrogenase, E1 component
ACEE_02685	COG1121	(ABC) transporter
ACEE_02690	COG0739	heme binding
ACEE_02695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACEE_02700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACEE_02710	COG0561	phosphatase activity
ACEE_02715	COG3850	Histidine kinase
ACEE_02720	COG1247	-acetyltransferase
ACEE_02725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACEE_02730	COG0393	Putative heavy-metal-binding
ACEE_02735	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ACEE_02740	COG2983	Belongs to the UPF0260 family
ACEE_02745	COG4221	oxidoreductase activity
ACEE_02765	COG1199	ATP-dependent helicase activity
ACEE_02770	COG1380	Effector of murein hydrolase LrgA
ACEE_02775	COG1346	cytolysis
ACEE_02780	COG1132	(ABC) transporter
ACEE_02785	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACEE_02790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACEE_02795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACEE_02800	COG0167	dihydroorotate dehydrogenase activity
ACEE_02805	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACEE_02810	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACEE_02815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACEE_02830	COG0582	viral genome integration into host DNA
ACEE_02860	COG0629	single-stranded DNA binding
ACEE_02915	COG3392	D12 class N6 adenine-specific DNA methyltransferase
ACEE_03010	COG4397	Mu-like prophage major head subunit gpT
ACEE_03015	COG4388	Caudovirus prohead serine protease
ACEE_03020	COG5005	Phage virion morphogenesis
ACEE_03025	COG2369	cell adhesion
ACEE_03030	COG4383	Mu-like prophage protein gp29
ACEE_03075	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACEE_03125	COG4396	Host-nuclease inhibitor protein Gam
ACEE_03150	COG2842	Transposition protein
ACEE_03160	COG3423	Transcriptional regulator
ACEE_03165	COG2932	Transcriptional regulator
ACEE_03175	COG4695	Portal protein
ACEE_03190	COG0737	Belongs to the 5'-nucleotidase family
ACEE_03195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACEE_03200	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ACEE_03205	COG0658	competence protein
ACEE_03205	COG2333	competence protein COMEC
ACEE_03225	COG2226	methyltransferase
ACEE_03230	COG3036	rescue of stalled ribosome
ACEE_03240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACEE_03245	COG1346	cytolysis
ACEE_03250	COG1380	Effector of murein hydrolase LrgA
ACEE_03270	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACEE_03275	COG2226	methyltransferase
ACEE_03280	COG0596	Alpha beta hydrolase
ACEE_03285	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ACEE_03290	COG0318	PFAM AMP-dependent synthetase and ligase
ACEE_03295	COG3264	Mechanosensitive ion channel
ACEE_03295	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ACEE_03300	COG3264	Mechanosensitive ion channel
ACEE_03300	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ACEE_03310	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ACEE_03315	COG1785	Belongs to the alkaline phosphatase family
ACEE_03325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACEE_03340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACEE_03345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACEE_03350	COG0539	negative regulation of cytoplasmic translation
ACEE_03355	COG0776	regulation of translation
ACEE_03360	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ACEE_03365	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ACEE_03370	COG0284	orotidine-5'-phosphate decarboxylase activity
ACEE_03375	COG0023	Translation Initiation Factor
ACEE_03380	COG3787	Belongs to the UPF0306 family
ACEE_03385	COG1811	Na channel or pump
ACEE_03395	COG3094	Invasion gene expression up-regulator, SirB
ACEE_03400	COG3028	Belongs to the UPF0307 family
ACEE_03405	COG0312	modulator of DNA gyrase
ACEE_03410	COG0440	acetolactate synthase activity
ACEE_03415	COG0028	Belongs to the TPP enzyme family
ACEE_03420	COG0288	reversible hydration of carbon dioxide
ACEE_03425	COG1278	Cold shock
ACEE_03440	COG0343	queuine tRNA-ribosyltransferase activity
ACEE_03445	COG3945	hemerythrin HHE cation binding domain
ACEE_03450	COG4991	sh3 domain protein
ACEE_03455	COG0306	phosphate transporter
ACEE_03460	COG1392	Phosphate transport regulator
ACEE_03465	COG4604	ABC transporter, ATP-binding protein
ACEE_03470	COG4605	iron ion homeostasis
ACEE_03475	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACEE_03480	COG4607	ABC-type enterochelin transport system periplasmic component
ACEE_03485	COG0305	Participates in initiation and elongation during chromosome replication
ACEE_03490	COG3100	YcgL domain-containing protein
ACEE_03495	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACEE_03500	COG0527	aspartate kinase activity
ACEE_03510	COG0248	Ppx GppA phosphatase
ACEE_03515	COG2731	YhcH YjgK YiaL family protein
ACEE_03520	COG1737	Transcriptional regulator
ACEE_03525	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACEE_03535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACEE_03540	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ACEE_03540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACEE_03545	COG0583	DNA-binding transcription factor activity
ACEE_03555	COG1444	tRNA N-acetyltransferase activity
ACEE_03560	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACEE_03565	COG0314	molybdopterin synthase activity
ACEE_03570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACEE_03575	COG0315	cyclic pyranopterin monophosphate synthase activity
ACEE_03585	COG3005	denitrification pathway
ACEE_03590	COG0243	molybdopterin cofactor binding
ACEE_03595	COG2363	Small membrane protein
ACEE_03610	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACEE_03615	COG0626	cystathionine gamma-synthase activity
ACEE_03620	COG1216	Glycosyl transferase, family 2
ACEE_03620	COG1442	glycosyl transferase family 8
ACEE_03625	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ACEE_03630	COG0741	lytic transglycosylase activity
ACEE_03650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACEE_03655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACEE_03665	COG1509	lysine 2,3-aminomutase activity
ACEE_03670	COG0017	Asparaginyl-tRNA synthetase
ACEE_03675	COG2925	Exonuclease
ACEE_03685	COG0613	PHP domain protein
ACEE_03695	COG2837	iron assimilation
ACEE_03705	COG0556	nucleotide-excision repair
ACEE_03715	COG0006	proline dipeptidase activity
ACEE_03720	COG1448	Aminotransferase
ACEE_03725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACEE_03735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACEE_03740	COG0625	glutathione transferase activity
ACEE_03745	COG2969	positive regulation of protein catabolic process
ACEE_03755	COG0589	response to stress
ACEE_03765	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACEE_03770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACEE_03915	COG0737	Belongs to the 5'-nucleotidase family
ACEE_03925	COG0280	phosphate acetyltransferase
ACEE_03925	COG0857	belongs to the CobB CobQ family
ACEE_03935	COG0277	FAD linked oxidase domain protein
ACEE_03940	COG2951	lytic endotransglycosylase activity
ACEE_03945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACEE_03950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACEE_03955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACEE_03960	COG0195	Participates in both transcription termination and antitermination
ACEE_03965	COG0779	Required for maturation of 30S ribosomal subunits
ACEE_03975	COG0285	dihydrofolate synthase activity
ACEE_03990	COG3956	TIGRFAM MazG family protein
ACEE_03995	COG0745	RESPONSE REGULATOR receiver
ACEE_04000	COG2205	protein histidine kinase activity
ACEE_04005	COG0577	efflux transmembrane transporter activity
ACEE_04005	COG1136	(ABC) transporter
ACEE_04010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACEE_04015	COG1494	fructose-1,6-bisphosphatase
ACEE_04020	COG3074	FtsZ-dependent cytokinesis
ACEE_04025	COG1435	thymidine kinase activity
ACEE_04030	COG1214	PFAM Peptidase M22, glycoprotease
ACEE_04035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACEE_04040	COG2321	neutral zinc metallopeptidase
ACEE_04045	COG1674	ftsk spoiiie
ACEE_04050	COG1522	sequence-specific DNA binding
ACEE_04055	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ACEE_04060	COG1846	Transcriptional regulator
ACEE_04060	COG1940	carbohydrate kinase activity
ACEE_04065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACEE_04070	COG0791	NLP P60 protein
ACEE_04075	COG0776	regulation of translation
ACEE_04080	COG0072	phenylalanine-tRNA ligase activity
ACEE_04085	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACEE_04090	COG0778	Nitroreductase
ACEE_04095	COG1823	symporter activity
ACEE_04100	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ACEE_04130	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACEE_04135	COG3105	Protein conserved in bacteria
ACEE_04145	COG0814	amino acid
ACEE_04150	COG0814	amino acid
ACEE_04155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACEE_04160	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACEE_04165	COG0517	IMP dehydrogenase activity
ACEE_04165	COG0516	GMP reductase activity
ACEE_04180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACEE_04185	COG3955	Domain of unknown function (DUF1919)
ACEE_04200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACEE_04205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACEE_04210	COG1309	transcriptional regulator
ACEE_04220	COG3083	sulfuric ester hydrolase activity
ACEE_04225	COG2828	Protein conserved in bacteria
ACEE_04230	COG0471	metal ion transport
ACEE_04235	COG2188	Transcriptional regulator
ACEE_04245	COG2814	Major facilitator Superfamily
ACEE_04255	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ACEE_04265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACEE_04270	COG1185	polyribonucleotide nucleotidyltransferase activity
ACEE_04275	COG4785	May be involved in cell division
ACEE_04280	COG0513	Belongs to the DEAD box helicase family
ACEE_04285	COG0590	tRNA wobble adenosine to inosine editing
ACEE_04295	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ACEE_04300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACEE_04305	COG0233	cytoplasmic translational termination
ACEE_04310	COG0528	UMP kinase activity
ACEE_04315	COG2194	sulfuric ester hydrolase activity
ACEE_04335	COG4178	(ABC) transporter
ACEE_04340	COG4774	siderophore transport
ACEE_04350	COG1840	ABC-type Fe3 transport system, periplasmic component
ACEE_04355	COG0433	COG0433 Predicted ATPase
ACEE_04390	COG4964	Belongs to the GSP D family
ACEE_04445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACEE_04450	COG0571	ribonuclease III activity
ACEE_04455	COG0681	Belongs to the peptidase S26 family
ACEE_04460	COG0481	GTPase activity
ACEE_04470	COG0351	phosphomethylpyrimidine kinase
ACEE_04475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACEE_04480	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACEE_04485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACEE_04490	COG2022	thiamine diphosphate biosynthetic process
ACEE_04500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACEE_04505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACEE_04510	COG1116	anion transmembrane transporter activity
ACEE_04520	COG1115	amino acid carrier protein
ACEE_04525	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ACEE_04530	COG3683	transport system, periplasmic component
ACEE_04535	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACEE_04540	COG0280	phosphate acetyltransferase
ACEE_04540	COG0281	malic enzyme
ACEE_04545	COG0471	metal ion transport
ACEE_04550	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ACEE_04550	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ACEE_04555	COG3051	citrate lyase alpha subunit
ACEE_04560	COG2301	Belongs to the HpcH HpaI aldolase family
ACEE_04565	COG3052	prosthetic group binding
ACEE_04570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACEE_04575	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ACEE_04580	COG0189	ligase activity
ACEE_04590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACEE_04600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACEE_04605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACEE_04605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACEE_04620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACEE_04625	COG0629	single-stranded DNA binding
ACEE_04645	COG1368	sulfuric ester hydrolase activity
ACEE_04650	COG3217	Mosc domain protein beta barrel domain protein
ACEE_04650	COG0633	Ferredoxin
ACEE_04655	COG1722	exodeoxyribonuclease VII activity
ACEE_04660	COG0142	geranyltranstransferase activity
ACEE_04670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACEE_04675	COG1530	ribonuclease E activity
ACEE_04680	COG1944	ATP diphosphatase activity
ACEE_04685	COG0500	methyltransferase
ACEE_04695	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ACEE_04720	COG0305	Participates in initiation and elongation during chromosome replication
ACEE_04755	COG0629	single-stranded DNA binding
ACEE_04770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACEE_04985	COG4172	Belongs to the ABC transporter superfamily
ACEE_04990	COG4171	peptide transport system, permease
ACEE_04995	COG4168	peptide transport system, permease
ACEE_05000	COG4166	transmembrane transport
ACEE_05005	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ACEE_05010	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACEE_05015	COG1879	ABC-type sugar transport system periplasmic component
ACEE_05020	COG1757	Na H antiporter
ACEE_05025	COG2916	Histone family protein nucleoid-structuring protein H-NS
ACEE_05030	COG1620	l-lactate permease
ACEE_05035	COG0247	lactate metabolic process
ACEE_05040	COG1139	Iron-sulfur cluster binding protein
ACEE_05045	COG1556	Lactate utilization protein
ACEE_05050	COG2949	membrane
ACEE_05055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACEE_05070	COG0586	Pfam SNARE associated Golgi protein
ACEE_05075	COG0187	DNA topoisomerase II activity
ACEE_05080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACEE_05085	COG1349	DNA-binding transcription factor activity
ACEE_05090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACEE_05095	COG2915	High frequency lysogenization protein hflD homolog
ACEE_05105	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACEE_05110	COG4988	ABC transporter
ACEE_05115	COG2911	Protein conserved in bacteria
ACEE_05120	COG0729	surface antigen
ACEE_05125	COG2861	carbohydrate metabolic process
ACEE_05130	COG4942	peptidase
ACEE_05135	COG0588	phosphoglycerate mutase activity
ACEE_05140	COG1279	arginine transmembrane transporter activity
ACEE_05145	COG0572	uridine kinase
ACEE_05150	COG0717	Belongs to the dCTP deaminase family
ACEE_05155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ACEE_05160	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ACEE_05165	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ACEE_05175	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACEE_05180	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACEE_05185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACEE_05190	COG4166	transmembrane transport
ACEE_05200	COG0444	Belongs to the ABC transporter superfamily
ACEE_05205	COG4608	Belongs to the ABC transporter superfamily
ACEE_05215	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACEE_05220	COG0747	negative chemotaxis
ACEE_05225	COG0814	amino acid
ACEE_05230	COG1760	l-serine dehydratase
ACEE_05245	COG0134	indole-3-glycerol-phosphate synthase activity
ACEE_05245	COG0135	phosphoribosylanthranilate isomerase activity
ACEE_05250	COG3098	single-species biofilm formation
ACEE_05255	COG0564	pseudouridine synthase activity
ACEE_05270	COG3025	triphosphatase activity
ACEE_05275	COG3106	COG3106 Predicted ATPase
ACEE_05280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACEE_05290	COG3069	C4-dicarboxylate transmembrane transporter activity
ACEE_05295	COG3340	Belongs to the peptidase S51 family
ACEE_05305	COG0495	leucyl-tRNA aminoacylation
ACEE_05310	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ACEE_05315	COG1466	dna polymerase III delta subunit
ACEE_05320	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACEE_05325	COG0237	dephospho-CoA kinase activity
ACEE_05335	COG1459	type II secretion system
ACEE_05340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACEE_05345	COG4969	Belongs to the N-Me-Phe pilin family
ACEE_05350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACEE_05360	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACEE_05360	COG0517	IMP dehydrogenase activity
ACEE_05395	COG0247	lactate metabolic process
ACEE_05400	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ACEE_05405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACEE_05410	COG0584	glycerophosphoryl diester phosphodiesterase
ACEE_05415	COG2271	Major facilitator Superfamily
ACEE_05425	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACEE_05435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACEE_05445	COG1160	GTP binding
ACEE_05450	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACEE_05450	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACEE_05455	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACEE_05460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACEE_05465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACEE_05470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACEE_05475	COG0318	PFAM AMP-dependent synthetase and ligase
ACEE_05485	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ACEE_05490	COG1595	DNA-templated transcription, initiation
ACEE_05505	COG0561	phosphatase activity
ACEE_05510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACEE_05515	COG0385	Bile acid
ACEE_05520	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ACEE_05530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACEE_05535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACEE_05540	COG0730	response to heat
ACEE_05545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACEE_05560	COG5339	Protein conserved in bacteria
ACEE_05570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACEE_05575	COG3383	formate dehydrogenase (NAD+) activity
ACEE_05575	COG0243	molybdopterin cofactor binding
ACEE_05580	COG3383	formate dehydrogenase (NAD+) activity
ACEE_05580	COG0243	molybdopterin cofactor binding
ACEE_05585	COG0437	4 iron, 4 sulfur cluster binding
ACEE_05590	COG2864	formate dehydrogenase
ACEE_05595	COG3058	Necessary for formate dehydrogenase activity
ACEE_05600	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ACEE_05605	COG3117	lipopolysaccharide transmembrane transporter activity
ACEE_05610	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACEE_05615	COG1137	ATPase activity
ACEE_05620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACEE_05625	COG1660	Displays ATPase and GTPase activities
ACEE_05630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACEE_05650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACEE_05660	COG0709	Synthesizes selenophosphate from selenide and ATP
ACEE_05675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACEE_05680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACEE_05685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACEE_05690	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACEE_05695	COG0564	pseudouridine synthase activity
ACEE_05710	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACEE_05715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACEE_05725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACEE_05730	COG0303	'Molybdopterin
ACEE_05735	COG2095	MarC family integral membrane protein
ACEE_05750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACEE_05760	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACEE_05770	COG0823	Involved in the tonB-independent uptake of proteins
ACEE_05775	COG3064	Membrane
ACEE_05780	COG0848	biopolymer transport protein
ACEE_05785	COG0811	peptide transport
ACEE_05790	COG0824	Thioesterase
ACEE_05805	COG1294	oxidase, subunit
ACEE_05810	COG1271	oxidase subunit
ACEE_05830	COG0494	nUDIX hydrolase
ACEE_05870	COG0271	Belongs to the BolA IbaG family
ACEE_05895	COG4172	Belongs to the ABC transporter superfamily
ACEE_05900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACEE_05905	COG0601	transmembrane transport
ACEE_05910	COG2255	four-way junction helicase activity
ACEE_05920	COG1177	transmembrane transport
ACEE_05925	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACEE_05930	COG3842	ATPase activity
ACEE_05935	COG0210	DNA helicase
ACEE_05940	COG0084	hydrolase, TatD family'
ACEE_05955	COG0531	amino acid
ACEE_05960	COG0531	amino acid
ACEE_05975	COG3047	cAMP biosynthetic process
ACEE_05980	COG0542	response to heat
ACEE_05985	COG1027	Aspartate ammonia-lyase
ACEE_05995	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACEE_06000	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACEE_06000	COG3583	domain protein
ACEE_06000	COG3064	Membrane
ACEE_06010	COG0720	synthase
ACEE_06015	COG0602	queuosine metabolic process
ACEE_06020	COG2271	Major facilitator Superfamily
ACEE_06025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACEE_06035	COG0795	lipopolysaccharide-transporting ATPase activity
ACEE_06040	COG0795	lipopolysaccharide-transporting ATPase activity
ACEE_06065	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ACEE_06075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACEE_06085	COG0861	Integral membrane protein TerC family
ACEE_06095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACEE_06100	COG0148	phosphopyruvate hydratase activity
ACEE_06105	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
ACEE_06120	COG1965	Belongs to the frataxin family
ACEE_06130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACEE_06135	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACEE_06140	COG0564	pseudouridine synthase activity
ACEE_06150	COG0205	6-phosphofructokinase activity
ACEE_06155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACEE_06165	COG1115	amino acid carrier protein
ACEE_06170	COG0628	permease
ACEE_06185	COG3307	-O-antigen
ACEE_06190	COG1519	Transferase
ACEE_06200	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACEE_06210	COG0802	atpase or kinase
ACEE_06215	COG1388	LysM domain
ACEE_06215	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACEE_06225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACEE_06230	COG2062	phosphohistidine phosphatase, SixA
ACEE_06235	COG0469	pyruvate kinase activity
ACEE_06240	COG0859	PFAM glycosyl transferase family 9
ACEE_06245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACEE_06250	COG0287	Prephenate dehydrogenase
ACEE_06250	COG1605	Chorismate mutase
ACEE_06255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACEE_06265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACEE_06270	COG1280	lysine exporter protein (LysE YggA)
ACEE_06275	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACEE_06280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACEE_06285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACEE_06290	COG4796	Type ii and iii secretion system protein
ACEE_06310	COG4972	Pilus assembly protein
ACEE_06315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACEE_06320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACEE_06325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACEE_06330	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ACEE_06335	COG0733	neurotransmitter:sodium symporter activity
ACEE_06340	COG0166	Belongs to the GPI family
ACEE_06370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACEE_06380	COG0551	DNA topoisomerase type I activity
ACEE_06390	COG2137	regulation of response to DNA damage stimulus
ACEE_06395	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACEE_06400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACEE_06410	COG1322	Protein conserved in bacteria
ACEE_06415	COG0512	Glutamine amidotransferase of anthranilate synthase
ACEE_06425	COG1560	Kdo2-lipid A biosynthetic process
ACEE_06440	COG4658	electron transport chain
ACEE_06450	COG4656	Part of a membrane complex involved in electron transport
ACEE_06455	COG2878	Part of a membrane complex involved in electron transport
ACEE_06460	COG4657	Part of a membrane complex involved in electron transport
ACEE_06470	COG2274	protein secretion by the type I secretion system
ACEE_06490	COG0583	DNA-binding transcription factor activity
ACEE_06500	COG2910	NAD(P)H-binding
ACEE_06505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACEE_06515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACEE_06520	COG2814	Major facilitator Superfamily
ACEE_06525	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ACEE_06535	COG2991	Protein conserved in bacteria
ACEE_06540	COG1477	protein flavinylation
ACEE_06545	COG2871	sodium ion transport
ACEE_06550	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACEE_06555	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACEE_06560	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACEE_06565	COG1805	sodium ion transport
ACEE_06570	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACEE_06575	COG0316	Belongs to the HesB IscA family
ACEE_06575	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACEE_06580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACEE_06585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACEE_06600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACEE_06605	COG1611	Belongs to the LOG family
ACEE_06610	COG3593	DNA synthesis involved in DNA repair
ACEE_06615	COG1254	Belongs to the acylphosphatase family
ACEE_06620	COG1929	Belongs to the glycerate kinase type-1 family
ACEE_06625	COG2610	gluconate transmembrane transporter activity
ACEE_06630	COG3835	regulator
ACEE_06635	COG4166	transmembrane transport
ACEE_06655	COG5413	integral membrane protein
ACEE_06665	COG0252	asparaginase activity
ACEE_06675	COG0583	DNA-binding transcription factor activity
ACEE_06680	COG1011	Hydrolase
ACEE_06685	COG0583	DNA-binding transcription factor activity
ACEE_06690	COG1162	GTPase activity
ACEE_06700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACEE_06705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACEE_06710	COG0537	adenosine 5'-monophosphoramidase activity
ACEE_06725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACEE_06730	COG3108	Peptidase M15
ACEE_06735	COG2989	Protein conserved in bacteria
ACEE_06740	COG0793	Belongs to the peptidase S41A family
ACEE_06745	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ACEE_06750	COG1278	Cold shock
ACEE_06755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACEE_06775	COG3068	Protein conserved in bacteria
ACEE_06790	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ACEE_06795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACEE_06800	COG1414	Transcriptional regulator
ACEE_06805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACEE_06905	COG3210	domain, Protein
ACEE_06910	COG2831	hemolysin activation secretion protein
ACEE_06920	COG3301	Polysulphide reductase, NrfD
ACEE_06925	COG0437	4 iron, 4 sulfur cluster binding
ACEE_06930	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ACEE_06940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACEE_06950	COG3978	acetolactate synthase activity
ACEE_06955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACEE_06960	COG0129	dihydroxy-acid dehydratase activity
ACEE_06980	COG3306	glycosyltransferase involved in LPS biosynthesis
ACEE_06985	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ACEE_06995	COG0006	proline dipeptidase activity
ACEE_07000	COG3030	protein affecting phage T7 exclusion by the F plasmid
ACEE_07020	COG3753	Protein conserved in bacteria
ACEE_07025	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ACEE_07030	COG0492	ferredoxin-NADP+ reductase activity
ACEE_07035	COG2376	Dihydroxyacetone kinase
ACEE_07040	COG1461	Dihydroxyacetone kinase
ACEE_07045	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ACEE_07045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACEE_07045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACEE_07050	COG3118	belongs to the thioredoxin family
ACEE_07060	COG0811	peptide transport
ACEE_07065	COG0848	biopolymer transport protein
ACEE_07070	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ACEE_07075	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACEE_07080	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACEE_07085	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACEE_07090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACEE_07095	COG0251	oxidation-reduction process
ACEE_07105	COG4608	Belongs to the ABC transporter superfamily
ACEE_07110	COG0444	Belongs to the ABC transporter superfamily
ACEE_07115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACEE_07120	COG0601	transmembrane transport
ACEE_07125	COG0747	negative chemotaxis
ACEE_07130	COG0747	negative chemotaxis
ACEE_07160	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACEE_07170	COG2197	response regulator
ACEE_07175	COG0366	Alpha amylase catalytic
ACEE_07180	COG1263	PTS System
ACEE_07180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACEE_07185	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACEE_07190	COG0354	folic acid binding
ACEE_07195	COG1561	YicC-like family, N-terminal region
ACEE_07205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACEE_07220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACEE_07225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACEE_07235	COG0745	RESPONSE REGULATOR receiver
ACEE_07240	COG2129	metallophosphoesterase
ACEE_07245	COG3172	ATPase kinase involved in NAD metabolism
ACEE_07250	COG0196	riboflavin kinase activity
ACEE_07255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACEE_07260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACEE_07265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACEE_07280	COG0018	arginyl-trna synthetase
ACEE_07285	COG3102	Protein conserved in bacteria
ACEE_07290	COG3133	Outer membrane lipoprotein
ACEE_07310	COG0193	aminoacyl-tRNA hydrolase activity
ACEE_07335	COG0747	negative chemotaxis
ACEE_07340	COG0601	transmembrane transport
ACEE_07345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACEE_07350	COG4172	Belongs to the ABC transporter superfamily
ACEE_07355	COG0497	DNA recombination
ACEE_07360	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACEE_07365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACEE_07370	COG0849	cell division
ACEE_07380	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACEE_07390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACEE_07395	COG0772	Belongs to the SEDS family
ACEE_07400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACEE_07410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACEE_07415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACEE_07420	COG0768	penicillin binding
ACEE_07425	COG3116	cell division
ACEE_07430	COG0275	rRNA processing
ACEE_07440	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ACEE_07445	COG3700	Belongs to the class B bacterial acid phosphatase family
ACEE_07455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACEE_07460	COG0549	Belongs to the carbamate kinase family
ACEE_07470	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ACEE_07475	COG1178	ABC-type Fe3 transport system permease component
ACEE_07480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACEE_07485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACEE_07490	COG2190	(PTS) system
ACEE_07495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACEE_07500	COG3059	membrane
ACEE_07510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACEE_07515	COG1621	beta-fructofuranosidase activity
ACEE_07560	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACEE_07570	COG0308	aminopeptidase N
ACEE_07575	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACEE_07580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACEE_07585	COG0295	cytidine deaminase activity
ACEE_07590	COG0697	spore germination
ACEE_07595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACEE_07600	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACEE_07605	COG2259	Doxx family
ACEE_07610	COG0431	NADPH-dependent FMN reductase
ACEE_07615	COG0142	geranyltranstransferase activity
ACEE_07620	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACEE_07625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACEE_07630	COG1028	Short-chain dehydrogenase reductase Sdr
ACEE_07635	COG1114	Component of the transport system for branched-chain amino acids
ACEE_07655	COG0805	protein transport
ACEE_07660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACEE_07665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACEE_07670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACEE_07680	COG2226	methyltransferase
ACEE_07685	COG0598	Magnesium transport protein CorA
ACEE_07705	COG3085	chromosome segregation
ACEE_07710	COG0076	glutamate decarboxylase activity
ACEE_07715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACEE_07725	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACEE_07730	COG2003	Belongs to the UPF0758 family
ACEE_07735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACEE_07745	COG1309	transcriptional regulator
ACEE_07760	COG1694	Mazg nucleotide pyrophosphohydrolase
ACEE_07765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACEE_07770	COG1923	regulation of RNA biosynthetic process
ACEE_07810	COG1490	D-aminoacyl-tRNA deacylase activity
ACEE_07820	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACEE_07840	COG0494	nUDIX hydrolase
ACEE_07845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACEE_07850	COG0174	glutamine synthetase
ACEE_07860	COG0594	ribonuclease P activity
ACEE_07865	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACEE_07875	COG3366	ferrous iron transmembrane transporter activity
ACEE_07880	COG0700	Nucleoside recognition
ACEE_07890	COG2818	Glycosylase
ACEE_07900	COG4942	peptidase
ACEE_07900	COG1388	LysM domain
ACEE_07915	COG1238	metal cluster binding
ACEE_07920	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACEE_07930	COG0149	triose-phosphate isomerase activity
ACEE_07945	COG1215	transferase activity, transferring glycosyl groups
ACEE_07950	COG1649	PFAM Uncharacterised BCR, COG1649
ACEE_07950	COG0726	polysaccharide deacetylase
ACEE_07960	COG1022	Amp-dependent synthetase and ligase
ACEE_07970	COG0676	glucose-6-phosphate 1-epimerase activity
ACEE_07975	COG2853	Lipoprotein
ACEE_07980	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ACEE_07985	COG3924	membrane
ACEE_07990	COG4145	pantothenate transmembrane transporter activity
ACEE_08015	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACEE_08025	COG4208	sulfate ABC transporter
ACEE_08030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACEE_08045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACEE_08050	COG2995	paraquat-inducible protein a
ACEE_08055	COG1305	Transglutaminase-like
ACEE_08065	COG2608	mercury ion transmembrane transporter activity
ACEE_08070	COG1012	belongs to the aldehyde dehydrogenase family
ACEE_08085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACEE_08090	COG1373	ATPase (AAA superfamily
ACEE_08160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACEE_08175	COG0477	Major facilitator Superfamily
ACEE_08195	COG1764	response to oxidative stress
ACEE_08200	COG1902	pentaerythritol trinitrate reductase activity
ACEE_08215	COG1764	response to oxidative stress
ACEE_08240	COG2207	Transcriptional regulator
ACEE_08245	COG0778	Nitroreductase
ACEE_08260	COG2610	gluconate transmembrane transporter activity
ACEE_08265	COG1028	Short-chain dehydrogenase reductase Sdr
ACEE_08270	COG0183	Belongs to the thiolase family
ACEE_08275	COG2031	fatty acid transporter
ACEE_08280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACEE_08285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACEE_08290	COG0583	DNA-binding transcription factor activity
ACEE_08295	COG0583	DNA-binding transcription factor activity
ACEE_08300	COG1902	pentaerythritol trinitrate reductase activity
ACEE_08305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACEE_08310	COG2171	N-acyltransferase activity
ACEE_08315	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACEE_08320	COG1368	sulfuric ester hydrolase activity
ACEE_08325	COG0511	ligase activity, forming carbon-carbon bonds
ACEE_08330	COG0439	Biotin carboxylase
ACEE_08335	COG1763	Mo-molybdopterin cofactor biosynthetic process
ACEE_08340	COG3084	Protein conserved in bacteria
ACEE_08345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACEE_08355	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACEE_08355	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACEE_08360	COG0742	ribosomal rna small subunit methyltransferase
ACEE_08365	COG1876	peptidase activity
ACEE_08375	COG1393	Belongs to the ArsC family
ACEE_08385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACEE_08400	COG0564	pseudouridine synthase activity
ACEE_08405	COG0668	transmembrane transport
ACEE_08410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACEE_08425	COG2116	formate transmembrane transporter activity
ACEE_08430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACEE_08450	COG0730	response to heat
ACEE_08480	COG0180	Tryptophanyl-tRNA synthetase
ACEE_08490	COG3120	sequence-specific DNA binding
ACEE_08495	COG1067	ATP-dependent peptidase activity
ACEE_08500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACEE_08510	COG4795	General secretion pathway protein
ACEE_08525	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACEE_08540	COG0443	Heat shock 70 kDa protein
ACEE_08545	COG1070	Carbohydrate kinase
ACEE_08550	COG2115	Belongs to the xylose isomerase family
ACEE_08555	COG4213	ABC transporter substrate-binding protein
ACEE_08560	COG1129	ABC transporter
ACEE_08565	COG4214	carbohydrate transport
ACEE_08570	COG2211	Major facilitator Superfamily
ACEE_08575	COG3507	Belongs to the glycosyl hydrolase 43 family
ACEE_08580	COG2207	Transcriptional regulator
ACEE_08580	COG1609	Transcriptional regulator
ACEE_08585	COG3590	peptidase
ACEE_08605	COG1442	glycosyl transferase family 8
ACEE_08635	COG3338	carbonate dehydratase activity
ACEE_08640	COG3161	chorismate lyase activity
ACEE_08645	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ACEE_08650	COG1522	sequence-specific DNA binding
ACEE_08655	COG2502	aspartate--ammonia ligase
ACEE_08665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACEE_08670	COG1595	DNA-templated transcription, initiation
ACEE_08680	COG0442	prolyl-tRNA aminoacylation
ACEE_08685	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACEE_08700	COG5295	Hep Hag repeat protein
ACEE_08700	COG5295	Hep Hag repeat protein
ACEE_08715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACEE_08720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ACEE_08725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACEE_08730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACEE_08735	COG0254	rRNA binding
ACEE_08740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACEE_08745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACEE_08765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACEE_08770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACEE_08775	COG0470	DNA polymerase III
ACEE_08780	COG0084	hydrolase, TatD family'
ACEE_08790	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACEE_08795	COG1215	transferase activity, transferring glycosyl groups
ACEE_08800	COG2832	Protein of unknown function (DUF454)
ACEE_08875	COG4139	cobalamin transport
ACEE_08885	COG2850	peptidyl-arginine hydroxylation
ACEE_08890	COG0335	large ribosomal subunit rRNA binding
ACEE_08895	COG0336	Belongs to the RNA methyltransferase TrmD family
ACEE_08900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACEE_08905	COG0228	four-way junction DNA binding
ACEE_08915	COG0202	RNA polymerase activity
ACEE_08920	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACEE_08925	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACEE_08930	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACEE_08940	COG0201	protein transport
ACEE_08945	COG0200	Binds to the 23S rRNA
ACEE_08950	COG1841	ribosomal large subunit assembly
ACEE_08955	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACEE_08960	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACEE_08965	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACEE_08970	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACEE_08975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACEE_08980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACEE_08985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACEE_08995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACEE_09000	COG0255	Belongs to the universal ribosomal protein uL29 family
ACEE_09005	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACEE_09010	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACEE_09015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACEE_09020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACEE_09025	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACEE_09030	COG0089	rRNA binding
ACEE_09035	COG0088	Forms part of the polypeptide exit tunnel
ACEE_09040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACEE_09045	COG0051	transcription antitermination factor activity, RNA binding
ACEE_09050	COG3070	regulator of competence-specific genes
ACEE_09055	COG0268	Binds directly to 16S ribosomal RNA
ACEE_09060	COG0728	peptidoglycan biosynthetic process
ACEE_09080	COG3276	selenocysteine insertion sequence binding
ACEE_09085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACEE_09090	COG0569	domain protein
ACEE_09100	COG2264	protein methyltransferase activity
ACEE_09110	COG0037	tRNA processing
ACEE_09120	COG4974	Belongs to the 'phage' integrase family
ACEE_09180	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ACEE_09195	COG1151	hydroxylamine reductase activity
ACEE_09200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACEE_09205	COG2244	polysaccharide biosynthetic process
ACEE_09210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACEE_09220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACEE_09225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACEE_09230	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ACEE_09255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACEE_09265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACEE_09270	COG0363	glucosamine-6-phosphate deaminase activity
ACEE_09275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACEE_09285	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ACEE_09295	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ACEE_09300	COG2267	carboxylic ester hydrolase activity
ACEE_09310	COG0606	chelatase, subunit chli
ACEE_09315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACEE_09320	COG0737	Belongs to the 5'-nucleotidase family
ACEE_09340	COG0222	ribosome binding
ACEE_09345	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACEE_09350	COG0081	regulation of translation
ACEE_09355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACEE_09365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACEE_09380	COG1297	OPT oligopeptide transporter protein
ACEE_09385	COG0758	DNA mediated transformation
ACEE_09395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACEE_09400	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
ACEE_09410	COG3691	Protein conserved in bacteria
ACEE_09425	COG0829	nickel cation binding
ACEE_09430	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACEE_09460	COG0831	urea catabolic process
ACEE_09470	COG1122	ATPase activity
ACEE_09475	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACEE_09480	COG0310	cobalt ion transport
ACEE_09485	COG0310	cobalt ion transport
ACEE_09490	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
ACEE_09495	COG0583	DNA-binding transcription factor activity
ACEE_09505	COG0490	domain, Protein
ACEE_09505	COG0471	metal ion transport
ACEE_09510	COG0471	metal ion transport
ACEE_09510	COG0490	domain, Protein
ACEE_09530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACEE_09535	COG1349	DNA-binding transcription factor activity
ACEE_09545	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ACEE_09550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACEE_09555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACEE_09560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACEE_09565	COG2900	Belongs to the SlyX family
ACEE_09570	COG0545	Peptidyl-prolyl cis-trans isomerase
ACEE_09575	COG2964	Protein conserved in bacteria
ACEE_09580	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACEE_09585	COG2923	Belongs to the DsrF TusC family
ACEE_09590	COG2168	tRNA wobble position uridine thiolation
ACEE_09595	COG1442	glycosyl transferase family 8
ACEE_09625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACEE_09630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACEE_09635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACEE_09640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACEE_09665	COG0357	Ribosomal RNA small subunit methyltransferase G
ACEE_09670	COG0445	tRNA wobble uridine modification
ACEE_09675	COG0561	phosphatase activity
ACEE_09685	COG3716	PTS system mannose fructose sorbose family IID component
ACEE_09690	COG3715	PTS system
ACEE_09695	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACEE_09695	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACEE_09700	COG2610	gluconate transmembrane transporter activity
ACEE_09705	COG3265	gluconokinase activity
ACEE_09710	COG1609	Transcriptional regulator
ACEE_09715	COG1609	Transcriptional regulator
ACEE_09720	COG1869	D-ribose catabolic process
ACEE_09730	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACEE_09735	COG1879	ABC-type sugar transport system periplasmic component
ACEE_09740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACEE_09750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACEE_09755	COG0765	amino acid transport
ACEE_09760	COG1126	abc transporter atp-binding protein
ACEE_09770	COG0799	negative regulation of ribosome biogenesis
ACEE_09775	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACEE_09780	COG0768	penicillin binding
ACEE_09785	COG0772	Belongs to the SEDS family
ACEE_09790	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACEE_09795	COG1686	Belongs to the peptidase S11 family
ACEE_09800	COG2921	Belongs to the UPF0250 family
ACEE_09805	COG0321	lipoyl(octanoyl) transferase activity
ACEE_09810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACEE_09825	COG4989	oxidoreductase activity
ACEE_09830	COG0783	Belongs to the Dps family
ACEE_09855	COG3681	Belongs to the UPF0597 family
ACEE_09870	COG0545	Peptidyl-prolyl cis-trans isomerase
ACEE_09875	COG2391	methyltransferase activity
ACEE_09880	COG0425	Belongs to the sulfur carrier protein TusA family
ACEE_09885	COG0235	Class ii aldolase
ACEE_09890	COG3623	hexulose-6-phosphate isomerase
ACEE_09915	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ACEE_09935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACEE_09940	COG1126	abc transporter atp-binding protein
ACEE_09955	COG3477	response to acidic pH
ACEE_09965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACEE_09970	COG4558	Periplasmic binding protein
ACEE_09975	COG4206	TonB-dependent receptor
ACEE_09975	COG1629	transport
ACEE_09995	COG2271	Major facilitator Superfamily
ACEE_10000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACEE_10005	COG1289	transmembrane transporter activity
ACEE_10025	COG0579	oxidoreductase
ACEE_10030	COG1304	FMN binding
ACEE_10045	COG1942	4-Oxalocrotonate Tautomerase
ACEE_10060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACEE_10065	COG4211	Belongs to the binding-protein-dependent transport system permease family
ACEE_10075	COG1879	ABC-type sugar transport system periplasmic component
ACEE_10085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACEE_10090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACEE_10090	COG0475	glutathione-regulated potassium exporter activity
ACEE_10105	COG1064	alcohol dehydrogenase
ACEE_10110	COG0778	Nitroreductase
ACEE_10140	COG1476	TRANSCRIPTIONal
ACEE_10150	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACEE_10160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACEE_10170	COG1442	glycosyl transferase family 8
ACEE_10175	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACEE_10195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACEE_10200	COG1072	(Pantothenic acid kinase))
ACEE_10225	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACEE_10245	COG0825	malonyl-CoA metabolic process
ACEE_10255	COG0204	Acyl-transferase
ACEE_10260	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ACEE_10275	COG0247	lactate metabolic process
ACEE_10275	COG0277	FAD linked oxidase domain protein
ACEE_10280	COG2050	protein possibly involved in aromatic compounds catabolism
ACEE_10300	COG0716	FMN binding
ACEE_10310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ACEE_10315	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ACEE_10320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ACEE_10325	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ACEE_10330	COG2731	YhcH YjgK YiaL family protein
ACEE_10335	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ACEE_10340	COG3545	Serine hydrolase
ACEE_10355	COG0625	glutathione transferase activity
ACEE_10360	COG0019	diaminopimelate decarboxylase activity
ACEE_10375	COG1119	ATPase activity
ACEE_10390	COG1739	Uncharacterized protein family UPF0029
ACEE_10395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACEE_10405	COG1970	mechanosensitive ion channel activity
ACEE_10425	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACEE_10435	COG0346	lactoylglutathione lyase activity
ACEE_10440	COG1194	a g-specific adenine glycosylase
ACEE_10445	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ACEE_10450	COG0741	lytic transglycosylase activity
ACEE_10475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACEE_10480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACEE_10485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACEE_10495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACEE_10500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ACEE_10510	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACEE_10515	COG1053	succinate dehydrogenase
ACEE_10520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACEE_10525	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ACEE_10530	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ACEE_10535	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACEE_10540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACEE_10545	COG3062	negative regulation of establishment of protein localization
ACEE_10550	COG0243	molybdopterin cofactor binding
ACEE_10555	COG0437	4 iron, 4 sulfur cluster binding
ACEE_10560	COG0348	domain, Protein
ACEE_10565	COG3043	anaerobic respiration
ACEE_10570	COG3005	denitrification pathway
ACEE_10575	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACEE_10585	COG3691	Protein conserved in bacteria
ACEE_10590	COG0814	amino acid
ACEE_10600	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACEE_10600	COG2918	glutathione biosynthetic process
ACEE_10605	COG0688	phosphatidylethanolamine metabolic process
ACEE_10610	COG1555	photosystem II stabilization
ACEE_10615	COG3061	Opacity-associated protein A
ACEE_10615	COG3266	domain, Protein
ACEE_10625	COG0859	PFAM glycosyl transferase family 9
ACEE_10630	COG0859	PFAM glycosyl transferase family 9
ACEE_10635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACEE_10640	COG0049	tRNA binding
ACEE_10645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACEE_10650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACEE_10655	COG1575	Belongs to the MenA family. Type 1 subfamily
ACEE_10660	COG1720	tRNA m6t6A37 methyltransferase activity
ACEE_10670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACEE_10690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACEE_10695	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACEE_10700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACEE_10705	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ACEE_10710	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACEE_10715	COG1755	Isoprenylcysteine carboxyl methyltransferase
ACEE_10725	COG1530	ribonuclease E activity
ACEE_10745	COG2153	protein acetylation
ACEE_10750	COG2927	DNA polymerase III (CHI subunit)
ACEE_10755	COG1652	LysM domain
ACEE_10760	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACEE_10765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACEE_10770	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACEE_10775	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACEE_10780	COG1045	serine acetyltransferase
ACEE_10785	COG0316	Belongs to the HesB IscA family
ACEE_10790	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ACEE_10800	COG2244	polysaccharide biosynthetic process
ACEE_10805	COG0562	UDP-galactopyranose mutase
ACEE_10815	COG3475	LICD family
ACEE_10820	COG0438	transferase activity, transferring glycosyl groups
ACEE_10825	COG1215	transferase activity, transferring glycosyl groups
ACEE_10830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACEE_10835	COG1063	alcohol dehydrogenase
ACEE_10845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACEE_10855	COG1088	dTDP-glucose 4,6-dehydratase activity
ACEE_10865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACEE_10875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACEE_10880	COG2824	Alkylphosphonate utilization operon protein PhnA
ACEE_10885	COG1858	cytochrome C peroxidase
ACEE_10895	COG0762	integral membrane protein
ACEE_10900	COG3171	Protein conserved in bacteria
ACEE_10905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACEE_10910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACEE_10915	COG0416	fatty acid biosynthetic process
ACEE_10920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACEE_10925	COG1399	metal-binding, possibly nucleic acid-binding protein
ACEE_10930	COG4137	Cytochrome C assembly protein
ACEE_10935	COG4536	flavin adenine dinucleotide binding
ACEE_10940	COG0733	neurotransmitter:sodium symporter activity
ACEE_10950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACEE_10950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACEE_10955	COG3715	PTS system
ACEE_10960	COG3716	PTS system mannose fructose sorbose family IID component
ACEE_10970	COG1482	cell wall glycoprotein biosynthetic process
ACEE_10980	COG1840	ABC-type Fe3 transport system, periplasmic component
ACEE_11000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACEE_11010	COG0557	exoribonuclease II activity
ACEE_11015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACEE_11020	COG1309	transcriptional regulator
ACEE_11025	COG0583	DNA-binding transcription factor activity
ACEE_11030	COG0678	peroxiredoxin activity
ACEE_11030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACEE_11040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACEE_11050	COG0625	glutathione transferase activity
ACEE_11060	COG2084	Dehydrogenase
ACEE_11065	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ACEE_11075	COG0732	type I restriction modification DNA specificity domain
ACEE_11085	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ACEE_11095	COG3630	sodium ion export across plasma membrane
ACEE_11100	COG1793	dna ligase
ACEE_11135	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACEE_11140	COG4133	protoheme IX ABC transporter activity
ACEE_11145	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACEE_11150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACEE_11155	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACEE_11165	COG1138	Cytochrome C-type biogenesis protein
ACEE_11185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACEE_11205	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACEE_11210	COG0792	nuclease activity
ACEE_11215	COG3107	peptidoglycan biosynthetic process
ACEE_11225	COG3101	peptidyl-lysine hydroxylation
ACEE_11230	COG4232	protein-disulfide reductase activity
ACEE_11240	COG3620	sequence-specific DNA binding
ACEE_11250	COG1881	PFAM PEBP family protein
ACEE_11255	COG1126	abc transporter atp-binding protein
ACEE_11260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACEE_11265	COG4215	(ABC) transporter
ACEE_11270	COG4160	amino acid transport
ACEE_11285	COG3099	Belongs to the UPF0263 family
ACEE_11290	COG0742	ribosomal rna small subunit methyltransferase
ACEE_11295	COG0552	protein localization to endoplasmic reticulum
ACEE_11300	COG2884	Cell division ATP-binding protein ftsE
ACEE_11305	COG2177	Part of the ABC transporter FtsEX involved in
ACEE_11325	COG1040	competence protein
ACEE_11330	COG0583	DNA-binding transcription factor activity
ACEE_11335	COG2813	Specifically methylates the guanine in position
ACEE_11345	COG0456	acetyltransferase
ACEE_11350	COG0513	Belongs to the DEAD box helicase family
ACEE_11360	COG0747	negative chemotaxis
ACEE_11365	COG1584	GPR1 FUN34 yaaH family protein
ACEE_11370	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACEE_11375	COG1120	ATPase activity
ACEE_11385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACEE_11400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACEE_11405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACEE_11410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACEE_11415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACEE_11420	COG1943	Transposase
ACEE_11435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACEE_11455	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACEE_11455	COG0140	phosphoribosyl-ATP diphosphatase activity
ACEE_11460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACEE_11465	COG0024	Methionine aminopeptidase
ACEE_11470	COG0210	DNA helicase
ACEE_11480	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACEE_11485	COG1136	(ABC) transporter
ACEE_11490	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACEE_11495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family