locus-tag	class	description
EXH44_00045	ENOG41076HS	cation diffusion facilitator family transporter
EXH44_00055	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EXH44_00060	ENOG4105C5S	asparaginyl-tRNA synthetase
EXH44_00065	ENOG4105C9X	ppx gppa phosphatase
EXH44_00105	ENOG4108R66	Conserved Protein
EXH44_00110	ENOG4105QEK	Transcriptional regulator
EXH44_00115	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EXH44_00120	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EXH44_00125	ENOG4105HDK	L-asparaginase
EXH44_00130	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
EXH44_00135	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EXH44_00140	ENOG4107QSN	dihydrolipoamide acetyltransferase
EXH44_00145	ENOG4107QN2	dihydrolipoyl dehydrogenase
EXH44_00155	ENOG4105CGF	Aromatic amino acid aminotransferase
EXH44_00165	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EXH44_00175	ENOG4105EKX	Restriction modification system DNA (Specificity
EXH44_00185	ENOG4105DZR	Type I site-specific deoxyribonuclease
EXH44_00190	ENOG4105E2R	ROK family
EXH44_00195	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
EXH44_00200	ENOG4105D8V	Glucose sorbosone dehydrogenase
EXH44_00205	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EXH44_00210	ENOG4108DNC	Involved in acetate metabolism (By similarity)
EXH44_00215	ENOG4108ZJT	translation initiation factor, Sui1
EXH44_00220	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
EXH44_00225	ENOG4105CFV	Tetratricopeptide repeat protein
EXH44_00230	ENOG4105Q4A	inner membrane protein yciS
EXH44_00235	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EXH44_00240	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EXH44_00245	ENOG4105CAT	Cytidine monophosphate kinase
EXH44_00250	ENOG4105C0H	protease
EXH44_00255	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
EXH44_00260	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
EXH44_00265	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EXH44_00280	ENOG4105M08	Membrane
EXH44_00290	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EXH44_00295	ENOG4105M00	molybdopterin converting factor, subunit 1
EXH44_00300	ENOG4108ZAF	Molybdopterin
EXH44_00305	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EXH44_00315	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
EXH44_00320	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
EXH44_00325	ENOG4105C2J	ABC transporter
EXH44_00330	ENOG4108HWV	)-transporter
EXH44_00340	ENOG4105CBT	Fructose-1,6-bisphosphatase
EXH44_00355	ENOG4105DBE	peroxidase
EXH44_00360	ENOG410650H	(LipO)protein
EXH44_00375	ENOG4108MG3	formate dehydrogenase
EXH44_00380	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
EXH44_00385	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
EXH44_00390	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
EXH44_00395	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EXH44_00400	ENOG4105BZN	citrate synthase
EXH44_00405	ENOG4107QIJ	Aconitate hydratase 2
EXH44_00410	ENOG4108HMX	isocitrate dehydrogenase (NADP)
EXH44_00415	ENOG4105SYT	Methylenetetrahydrofolate reductase
EXH44_00430	ENOG4108IYH	Dna topoisomerase
EXH44_00435	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
EXH44_00440	ENOG4105CFH	Aspartokinase
EXH44_00445	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EXH44_00450	ENOG4105CRK	lysyL-tRNA synthetase
EXH44_00455	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EXH44_00460	ENOG4105EGS	Mechanosensitive ion channel
EXH44_00465	ENOG4105CEY	Amp-dependent synthetase and ligase
EXH44_00470	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
EXH44_00475	ENOG4105EV9	Alpha Beta Hydrolase
EXH44_00480	ENOG4105KB2	stringent starvation protein b
EXH44_00485	ENOG4107MKT	Stringent starvation protein a
EXH44_00490	ENOG41090HJ	UPF0265 protein
EXH44_00500	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
EXH44_00505	ENOG4107RAQ	aminopeptidase
EXH44_00510	ENOG4105DXN	mazG family
EXH44_00515	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EXH44_00520	ENOG4105E0F	Histidine kinase
EXH44_00525	ENOG4105C94	Transporter
EXH44_00530	ENOG4105C94	Transporter
EXH44_00535	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EXH44_00540	ENOG4107QNR	UPF0135 protein
EXH44_00545	ENOG4105C4Y	ABC transporter
EXH44_00550	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
EXH44_00555	ENOG4105KWI	UPF0339 protein
EXH44_00570	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EXH44_00575	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
EXH44_00585	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EXH44_00595	ENOG4107104	thymidine kinase
EXH44_00600	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EXH44_00605	ENOG4105E0M	Sulfatase
EXH44_00610	ENOG4105QVC	MOSC domain-containing protein
EXH44_00620	ENOG4105CTB	Polyprenyl synthetase
EXH44_00625	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EXH44_00630	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EXH44_00635	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
EXH44_00640	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
EXH44_00645	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
EXH44_00655	ENOG4105EIF	outer membrane protein W
EXH44_00660	ENOG4108W1A	pseudouridine synthase
EXH44_00665	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EXH44_00670	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXH44_00675	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
EXH44_00680	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EXH44_00685	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
EXH44_00695	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EXH44_00705	ENOG4108K4B	hydrolase
EXH44_00715	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EXH44_00720	ENOG4105T95	Thiol disulfide interChange protein
EXH44_00725	ENOG4105DR5	peptidase
EXH44_00730	ENOG4105FDK	ABC transporter
EXH44_00735	ENOG4105FAV	ABC, transporter
EXH44_00740	ENOG4105E7A	Glutamine amidotransferase
EXH44_00745	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EXH44_00755	ENOG4107QTF	adenylosuccinate lyase
EXH44_00760	ENOG4105E98	transcriptional regulator DeoR family
EXH44_00845	ENOG4108ZHR	arsR family transcriptional regulator
EXH44_00860	ENOG4105F9F	transposase
EXH44_00865	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EXH44_00900	ENOG4108R0M	Aminoglycoside
EXH44_00940	ENOG4105F9F	transposase
EXH44_00965	ENOG4105F9F	transposase
EXH44_00995	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
EXH44_01000	ENOG4105C29	acyl-CoA thioesterase
EXH44_01020	ENOG4108Z6B	deaminase
EXH44_01025	ENOG4105C1J	atp-dependent rna helicase
EXH44_01030	ENOG4105RT1	May be involved in cell division (By similarity)
EXH44_01035	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EXH44_01040	ENOG4108J59	Extracellular solute-binding protein, family 5
EXH44_01045	ENOG4105D2M	Aldolase
EXH44_01065	ENOG4105F3R	pts system mannose fructose sorbose family iid
EXH44_01070	ENOG4105ETZ	PTS System
EXH44_01075	ENOG4108UZY	PTS System
EXH44_01080	ENOG4105E70	isomerase
EXH44_01085	ENOG4105E98	transcriptional regulator DeoR family
EXH44_01090	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
EXH44_01095	ENOG4105N42	UPF0307 protein
EXH44_01105	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
EXH44_01110	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
EXH44_01120	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
EXH44_01130	ENOG4105DVA	methyltransferase
EXH44_01140	ENOG4105CHW	UPF0052 protein
EXH44_01145	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
EXH44_01150	ENOG4105YES	addiction module antidote protein
EXH44_01155	ENOG4105VUH	addiction module killer protein
EXH44_01160	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
EXH44_01165	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
EXH44_01170	ENOG41080IJ	Diacylglycerol kinase
EXH44_01180	ENOG4105CGH	5'-nucleotidase
EXH44_01195	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
EXH44_01200	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EXH44_01205	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EXH44_01210	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
EXH44_01215	ENOG4107QR9	Iron-sulfur cluster binding protein
EXH44_01220	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
EXH44_01225	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
EXH44_01230	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
EXH44_01235	ENOG4105EJ9	Membrane
EXH44_01240	ENOG4105CSM	endonuclease III
EXH44_01245	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
EXH44_01250	ENOG4105CC0	LysR family Transcriptional regulator
EXH44_01255	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
EXH44_01260	ENOG4108EU3	peptide transport system, permease
EXH44_01270	ENOG4108EVY	peptide transport periplasmic protein
EXH44_01280	ENOG41061WM	D-Alanyl-D-Alanine
EXH44_01285	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EXH44_01290	ENOG4108I6E	Sulfatase
EXH44_01295	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EXH44_01305	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
EXH44_01310	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXH44_01315	ENOG4105CSA	Coproporphyrinogen iii oxidase
EXH44_01320	ENOG4105EJQ	L-serine dehydratase
EXH44_01325	ENOG4105C44	Serine transporter
EXH44_01330	ENOG4105C8N	cysteinyl-tRNA synthetase
EXH44_01335	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EXH44_01340	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
EXH44_01345	ENOG4105D82	Glutamate dehydrogenase
EXH44_01360	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EXH44_01365	ENOG4108JJ8	(ABC) transporter
EXH44_01370	ENOG4108JJ9	ABC, transporter
EXH44_01375	ENOG4105MA0	exported protein
EXH44_01380	ENOG4105CFU	surface antigen
EXH44_01385	ENOG4105PXI	polysaccharide deacetylase
EXH44_01390	ENOG41063SB	peptidase
EXH44_01395	ENOG4105CEY	Amp-dependent synthetase and ligase
EXH44_01400	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
EXH44_01405	ENOG4105VQK	sigma E regulatory protein, MucB RseB
EXH44_01415	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
EXH44_01420	ENOG4105K9H	YciI-like protein
EXH44_01425	ENOG4105NAU	thioesterase Superfamily protein
EXH44_01430	ENOG4107835	probably involved in intracellular septation (By similarity)
EXH44_01440	ENOG4105PQ6	UPF0208 membrane protein
EXH44_01445	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EXH44_01460	ENOG4105E0X	reductase
EXH44_01465	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EXH44_01480	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EXH44_01485	ENOG4105VNG	YcgL domain-containing protein
EXH44_01490	ENOG4105CDU	Replicative dna helicase
EXH44_01495	ENOG4105DB7	PHP domain protein
EXH44_01505	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
EXH44_01510	ENOG4105CJB	Exodeoxyribonuclease I
EXH44_01515	ENOG4105E3A	(ABC) transporter
EXH44_01520	ENOG4105DA5	(ABC) transporter
EXH44_01525	ENOG4107QMP	dna polymerase iii subunits gamma and tau
EXH44_01530	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EXH44_01535	ENOG4105D8G	Major Facilitator superfamily
EXH44_01540	ENOG4105II7	pyrroline-5-carboxylate reductase
EXH44_01550	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EXH44_01555	ENOG4105WVQ	Fe-S assembly protein IscX
EXH44_01560	ENOG4108ZIT	Ferredoxin, 2FE-2S
EXH44_01570	ENOG4108RF1	Protein of unknown function DUF2625
EXH44_01580	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
EXH44_01585	ENOG4108Z4V	iron-sulfur cluster assembly
EXH44_01590	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
EXH44_01595	ENOG4105C3J	Cysteine desulfurase
EXH44_01600	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EXH44_01605	ENOG4105KZW	UPF0381 protein
EXH44_01610	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
EXH44_01615	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EXH44_01620	ENOG4105C28	cystathionine
EXH44_01625	ENOG4105C7N	Xanthine uracil vitamin C permease
EXH44_01635	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EXH44_01640	ENOG4105EMU	Dehydrogenase
EXH44_01645	ENOG4108ZZ3	UPF0260 protein
EXH44_01650	ENOG4105K8R	UPF0145 protein
EXH44_01655	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EXH44_01660	ENOG4105D1S	lipid A biosynthesis
EXH44_01670	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
EXH44_01680	ENOG4105EUJ	GTP cyclohydrolase i
EXH44_01685	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
EXH44_01690	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EXH44_01695	ENOG4108UMI	ABC transporter, permease
EXH44_01700	ENOG4105D01	(LipO)protein
EXH44_01710	ENOG4105D01	(LipO)protein
EXH44_01715	ENOG4105D01	(LipO)protein
EXH44_01735	ENOG4105E9M	CRISPR-associated protein, Csn1 family
EXH44_01740	ENOG4105D1H	recombination factor protein RarA
EXH44_01750	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
EXH44_01755	ENOG4105DFF	Rod shape-determining protein mreb
EXH44_01760	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EXH44_01765	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EXH44_01775	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
EXH44_01780	ENOG4105EUB	pirin domain protein
EXH44_01790	ENOG4105F9F	transposase
EXH44_01795	ENOG4108BY2	phosphohistidine phosphatase
EXH44_01800	ENOG4105CA9	Pyruvate kinase
EXH44_01805	ENOG4107QYX	exodeoxyribonuclease v alpha
EXH44_01810	ENOG4105CHH	sulfate transporter
EXH44_01815	ENOG4105CPW	cytochrome b561
EXH44_01825	ENOG4105CH2	amidohydrolase
EXH44_01830	ENOG4108PGP	mmge prpd family protein
EXH44_01840	ENOG4108HW4	amino acid AbC transporter
EXH44_01845	ENOG4105EAB	amino acid AbC transporter
EXH44_01850	ENOG4108XSB	acetyltransferase, (GNAT) family
EXH44_01855	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
EXH44_01865	ENOG4107R11	Transcriptional regulator
EXH44_01870	ENOG4105PAD	Hydrolase
EXH44_01875	ENOG4105ETT	transcriptional Regulator, LysR family
EXH44_01880	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EXH44_01885	ENOG4105M4H	endoribonuclease L-psp
EXH44_01895	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EXH44_01915	ENOG4105CDY	transcriptional regulatory protein
EXH44_01920	ENOG4108TIT	dATP pyrophosphohydrolase
EXH44_01930	ENOG4105C9M	aspartyl-trna synthetase
EXH44_01935	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EXH44_01945	ENOG4108VMM	UPF0756 membrane protein
EXH44_01950	ENOG4105CQ7	ATP-dependent helicase
EXH44_01955	ENOG4105BZU	Histidine kinase
EXH44_01960	ENOG4108TZV	Membrane
EXH44_01965	ENOG4108DG9	Smr protein MutS2
EXH44_01970	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
EXH44_01975	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
EXH44_01980	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
EXH44_01990	ENOG4107QHF	type ii secretion system protein e
EXH44_01995	ENOG4105D7Q	type ii secretion system
EXH44_02005	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EXH44_02010	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
EXH44_02015	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EXH44_02020	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EXH44_02025	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EXH44_02035	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EXH44_02040	ENOG4105DZP	Membrane-associated zinc metalloprotease
EXH44_02045	ENOG4105KNE	Phosphatidate cytidylyltransferase
EXH44_02050	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EXH44_02055	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EXH44_02060	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
EXH44_02065	ENOG4105EYK	Phosphatidylglycerophosphatase B
EXH44_02070	ENOG4105HBR	Rna-binding protein
EXH44_02075	ENOG4106WTF	Glycosyl transferase, family 2
EXH44_02080	ENOG4105M5K	heptosyltransferase
EXH44_02085	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EXH44_02090	ENOG4105VFB	Binds the 23S rRNA (By similarity)
EXH44_02095	ENOG4105W1T	Glycosyl Transferase
EXH44_02105	ENOG4108XNZ	glycosyl transferase
EXH44_02110	ENOG4105EMY	transcriptional regulator
EXH44_02115	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EXH44_02130	ENOG4108V0P	LemA family
EXH44_02135	ENOG4106K28	UPF0283 membrane protein
EXH44_02140	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
EXH44_02150	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
EXH44_02155	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EXH44_02160	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
EXH44_02175	ENOG4105E02	MotA TolQ exbB proton channel
EXH44_02180	ENOG4107YD3	Thioesterase
EXH44_02195	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EXH44_02200	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EXH44_02210	ENOG410601J	HemY protein
EXH44_02215	ENOG4105ECF	c-methyltransferase
EXH44_02220	ENOG41076E6	Uroporphyrinogen-III Synthase
EXH44_02225	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EXH44_02230	ENOG4105BZG	amino acid carrier protein
EXH44_02235	ENOG4108JQ7	(ABC) transporter
EXH44_02240	ENOG4105C3U	ABC transporter
EXH44_02245	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EXH44_02250	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EXH44_02255	ENOG4108J59	Extracellular solute-binding protein, family 5
EXH44_02270	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EXH44_02275	ENOG4105D38	putrescine abc transporter
EXH44_02280	ENOG4105F38	ABC transporter, permease
EXH44_02285	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXH44_02290	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
EXH44_02295	ENOG4108UYE	Lactoylglutathione lyase
EXH44_02300	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
EXH44_02320	ENOG4107H52	Dicarboxylate transport
EXH44_02330	ENOG41090HT	Inherit from COG: transposase
EXH44_02350	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
EXH44_02355	ENOG4105BZM	domain protein
EXH44_02360	ENOG4108P11	EamA-like transporter family
EXH44_02365	ENOG4105CBX	hi0933 family
EXH44_02370	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EXH44_02375	ENOG4105M6F	mutator MutT protein
EXH44_02380	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EXH44_02405	ENOG4105M85	Bola protein
EXH44_02410	ENOG4105IEY	(LipO)protein
EXH44_02415	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
EXH44_02420	ENOG4108UJU	UPF0301 protein
EXH44_02425	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EXH44_02430	ENOG4108UUE	Transcriptional regulator
EXH44_02435	ENOG4105VIE	preprotein translocase, subunit YajC
EXH44_02440	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EXH44_02445	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EXH44_02480	ENOG4105EUB	pirin domain protein
EXH44_02485	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EXH44_02490	ENOG4105DC8	reductase
EXH44_02495	ENOG4108TEB	UPF0114 protein
EXH44_02500	ENOG4108535	NAD dependent epimerase/dehydratase family
EXH44_02505	ENOG4108TVJ	Nitroreductase
EXH44_02515	ENOG4105D2N	Aldolase
EXH44_02520	ENOG4105BZA	Phosphoglycerate kinase
EXH44_02525	ENOG4105C8P	)-transporter
EXH44_02530	ENOG4105F9F	transposase
EXH44_02535	ENOG4105X3C	heme exporter protein
EXH44_02540	ENOG41060IM	Heme exporter protein
EXH44_02545	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
EXH44_02550	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
EXH44_02555	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
EXH44_02565	ENOG4105N21	Membrane
EXH44_02570	ENOG4105CUT	histidyl-tRNA synthetase
EXH44_02575	ENOG4105C5I	Dehydrogenase
EXH44_02580	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
EXH44_02585	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
EXH44_02590	ENOG4105D07	Signal peptide peptidase, SppA
EXH44_02595	ENOG41069NU	Nitroreductase
EXH44_02600	ENOG4108BPE	-transporting atpase
EXH44_02605	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EXH44_02610	ENOG410903C	(LipO)protein
EXH44_02615	ENOG4105C5X	domain protein
EXH44_02620	ENOG4105EAQ	(twin-arginine translocation) pathway signal
EXH44_02625	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
EXH44_02630	ENOG4105CN1	protease
EXH44_02635	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
EXH44_02640	ENOG4105VEQ	Cold shock protein
EXH44_02645	ENOG4105C3M	thioredoxin reductase
EXH44_02650	ENOG4107QR8	Thioredoxin
EXH44_02660	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EXH44_02665	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
EXH44_02670	ENOG4105ECP	epimerase
EXH44_02675	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EXH44_02680	ENOG4105DZ2	Transcriptional regulator
EXH44_02685	ENOG4108ZPB	UPF0306 protein
EXH44_02690	ENOG4105C8J	)-transporter
EXH44_02695	ENOG4105DFE	Dna adenine methylase
EXH44_02700	ENOG4105D49	3-dehydroquinate synthase
EXH44_02705	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EXH44_02710	ENOG4108JQC	penicillin-binding protein 1A
EXH44_02735	ENOG4105E4G	Type IV pilus
EXH44_02740	ENOG4107YIM	Involved in the transcription termination process (By similarity)
EXH44_02745	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
EXH44_02750	ENOG4108ZAI	phosphatidylglycerophosphatase a
EXH44_02755	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
EXH44_02760	ENOG4105D4X	repressor
EXH44_02765	ENOG4105RHG	
EXH44_02770	ENOG4105Z2P	Protein of unknown function (DUF465)
EXH44_02780	ENOG4105C4R	Atp-dependent dna helicase
EXH44_02785	ENOG4105C12	Phosphoribosylglycinamide synthetase
EXH44_02790	ENOG4105E09	nadh pyrophosphatase
EXH44_02795	ENOG4105DMR	ABC, transporter
EXH44_02800	ENOG4105GBT	ABC transporter
EXH44_02805	ENOG4106PMH	Extracellular solute-binding protein family 3
EXH44_02810	ENOG4105E5Z	arginine transporter ATP-binding subunit
EXH44_02815	ENOG4108JQ7	(ABC) transporter
EXH44_02820	ENOG4105C3U	ABC transporter
EXH44_02825	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EXH44_02830	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EXH44_02835	ENOG4105DEF	Extracellular solute-binding protein, family 5
EXH44_02840	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EXH44_02845	ENOG4108VBH	Uncharacterized protein conserved in bacteria (DUF2251)
EXH44_02850	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EXH44_02870	ENOG4105D60	lipoprotein releasing system transmembrane protein
EXH44_02880	ENOG4105C5F	glutamine synthetase
EXH44_02885	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
EXH44_02890	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
EXH44_02905	ENOG4105CG3	alpha amylase, catalytic region
EXH44_02910	ENOG4105C5Y	PTS System
EXH44_02915	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EXH44_02920	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EXH44_02935	ENOG4105C01	Dihydroxy-acid dehydratase
EXH44_02940	ENOG4105C4R	Atp-dependent dna helicase
EXH44_02945	ENOG4107QKA	exodeoxyribonuclease V beta
EXH44_02950	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
EXH44_02955	ENOG4105EG2	ABC transporter, permease
EXH44_02960	ENOG4105D56	permease protein
EXH44_02965	ENOG4107FKK	extracellular solute-binding protein family 1
EXH44_02970	ENOG4108IJ9	(ABC) transporter
EXH44_02975	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
EXH44_02980	ENOG4107W52	maltose operon periplasmic protein
EXH44_02985	ENOG4107T9C	Alpha amylase catalytic region
EXH44_02990	ENOG41090BQ	Glutaredoxin
EXH44_02995	ENOG4105CI3	gtp-binding protein typa
EXH44_03000	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
EXH44_03005	ENOG4105BZ1	(ABC) transporter
EXH44_03025	ENOG4105K59	histidine triad (HIT) protein
EXH44_03035	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EXH44_03040	ENOG41063JG	Transcriptional regulator
EXH44_03045	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EXH44_03050	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EXH44_03055	ENOG4105K70	DNA-binding protein
EXH44_03060	ENOG4105R2J	Conserved Protein
EXH44_03065	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EXH44_03070	ENOG4105DSB	aldose 1-epimerase
EXH44_03075	ENOG4105CH7	arginosuccinase
EXH44_03080	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
EXH44_03085	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
EXH44_03095	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EXH44_03105	ENOG4105CD8	aminopeptidase N
EXH44_03110	ENOG4105DFA	alanine racemase domain protein
EXH44_03115	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
EXH44_03120	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EXH44_03125	ENOG4108Z6Z	Transcriptional regulator
EXH44_03135	ENOG4105C59	p-type ATPase
EXH44_03140	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EXH44_03145	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EXH44_03150	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EXH44_03160	ENOG4105CPF	Cell wall formation (By similarity)
EXH44_03165	ENOG4105DFU	Cell wall formation (By similarity)
EXH44_03170	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EXH44_03175	ENOG4105CNI	cell division protein FtsW
EXH44_03180	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EXH44_03185	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EXH44_03190	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
EXH44_03205	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EXH44_03210	ENOG4105CJN	penicillin-binding protein
EXH44_03220	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EXH44_03225	ENOG4108V6E	Cell division protein mraZ
EXH44_03240	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
EXH44_03245	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EXH44_03250	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EXH44_03255	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
EXH44_03260	ENOG4105DE4	1-phosphofructokinase
EXH44_03265	ENOG4105DM4	PTS System
EXH44_03270	ENOG4105C2X	Arabinose 5-phosphate isomerase
EXH44_03275	ENOG4108RRZ	Transcription elongation factor GreB
EXH44_03280	ENOG4105DY2	Paraquat-inducible protein b
EXH44_03285	ENOG41090R7	Ferric uptake
EXH44_03290	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
EXH44_03295	ENOG4105NNH	LexA regulated protein
EXH44_03305	ENOG4105MJ2	Competence protein
EXH44_03310	ENOG4105EYA	deoxyribonuclease
EXH44_03325	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EXH44_03330	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EXH44_03335	ENOG4105C0H	protease
EXH44_03340	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EXH44_03345	ENOG4105FE9	pseudouridine synthase
EXH44_03350	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
EXH44_03355	ENOG4105CRQ	synthase (Component I)
EXH44_03360	ENOG4105DDQ	anthranilate synthase
EXH44_03375	ENOG4105CKW	Inner membrane protein yedI
EXH44_03395	ENOG4105CJP	fad dependent oxidoreductase
EXH44_03400	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EXH44_03405	ENOG4105VFK	BolA family
EXH44_03415	ENOG4105E3I	toluene tolerance
EXH44_03420	ENOG4107PE3	Mammalian cell entry related domain protein
EXH44_03425	ENOG4105CY3	ABC transporter, permease
EXH44_03430	ENOG4105DHJ	ABC, transporter
EXH44_03435	ENOG4105W4M	Transport-associated protein
EXH44_03440	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
EXH44_03445	ENOG41082RQ	UPF0102 protein
EXH44_03455	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EXH44_03460	ENOG4108RMU	ferritin dps family protein
EXH44_03465	ENOG4105JIM	Phosphatidylserine synthase
EXH44_03470	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EXH44_03475	ENOG4105DTN	riboflavin biosynthesis protein ribF
EXH44_03515	ENOG4106AFN	Lyase and sodium transporter (By similarity)
EXH44_03520	ENOG4107QSA	Oxaloacetate decarboxylase
EXH44_03525	ENOG4105D9Q	decarboxylase (Beta subunit)
EXH44_03530	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EXH44_03545	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
EXH44_03550	ENOG4105VEJ	Heat shock protein
EXH44_03560	ENOG4107RZZ	dna polymerase iii epsilon subunit
EXH44_03570	ENOG4105DVI	reductase, NrfD
EXH44_03575	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
EXH44_03580	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
EXH44_03585	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
EXH44_03620	ENOG4108JA2	transcriptioN-repair coupling factor
EXH44_03635	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
EXH44_03645	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EXH44_03650	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EXH44_03655	ENOG4108VPT	UPF0234 protein
EXH44_03660	ENOG4105EAC	phosphoserine phosphatase
EXH44_03665	ENOG41062Z9	Membrane
EXH44_03675	ENOG4108JQ1	Dehydrogenase
EXH44_03680	ENOG4105E66	phosphoriboisomerase A
EXH44_03685	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EXH44_03690	ENOG4105C7B	Threonine dehydratase
EXH44_03695	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EXH44_03700	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
EXH44_03710	ENOG4108R96	Methyltransferase, YaeB family
EXH44_03715	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
EXH44_03720	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EXH44_03725	ENOG4105MFV	ABC-2 type transporter
EXH44_03765	ENOG4105D3Q	Sugar transferase
EXH44_03770	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
EXH44_03775	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
EXH44_03785	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EXH44_03790	ENOG4105PF3	O-Antigen polymerase
EXH44_03800	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EXH44_03805	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EXH44_03810	ENOG4106HK8	GPR1 FUN34 yaaH family protein
EXH44_03815	ENOG4107RUE	extracellular solute-binding protein family 1
EXH44_03820	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EXH44_03830	ENOG4105C26	Dehydrogenase
EXH44_03835	ENOG4105CK7	Sodium proline symporter
EXH44_03840	ENOG4108IPT	Naphthoate synthase
EXH44_03850	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EXH44_03855	ENOG4108IQE	Amp-dependent synthetase and ligase
EXH44_03865	ENOG4105EIP	mannose-6-phosphate isomerase
EXH44_03870	ENOG4108NK4	UPF0266 membrane protein
EXH44_03875	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EXH44_03880	ENOG4105C5Y	PTS System
EXH44_03885	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
EXH44_03890	ENOG4105KZ7	phosphocarrier protein hpr
EXH44_03895	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EXH44_03905	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EXH44_03910	ENOG4105NXV	High-affinity zinc uptake system protein
EXH44_03915	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
EXH44_03920	ENOG4105EM2	membrane
EXH44_03930	ENOG4108XTF	Outer Membrane Lipoprotein
EXH44_03935	ENOG4105NBI	YecM protein
EXH44_03940	ENOG4105C75	arginyL-tRNA synthetase
EXH44_03945	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EXH44_03955	ENOG4105EZE	Cupin 4 family protein
EXH44_03960	ENOG4105CFC	Transporter
EXH44_03965	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
EXH44_03970	ENOG4108RXX	maleylacetoacetate isomerase
EXH44_03975	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
EXH44_04005	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
EXH44_04020	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
EXH44_04025	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
EXH44_04030	ENOG4108VVQ	metallophosphoesterase
EXH44_04035	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
EXH44_04040	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EXH44_04055	ENOG4105EAB	amino acid AbC transporter
EXH44_04060	ENOG4105E5Q	amino acid AbC transporter
EXH44_04065	ENOG4105CDA	abc transporter atp-binding protein
EXH44_04070	ENOG4105EHV	domain protein
EXH44_04075	ENOG4105C5Q	Transcriptional regulator
EXH44_04095	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXH44_04100	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
EXH44_04105	ENOG4105JC1	sterol-binding domain protein
EXH44_04110	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EXH44_04115	ENOG4108RR8	protoporphyrinogen oxidase
EXH44_04120	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
EXH44_04130	ENOG4105C6T	cysteine synthase
EXH44_04135	ENOG41083KI	ribonuclease, T2
EXH44_04140	ENOG4105GPY	SprT protein
EXH44_04150	ENOG4105E0A	ABC, transporter
EXH44_04155	ENOG4105J76	Periplasmic binding protein
EXH44_04160	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
EXH44_04165	ENOG4105E0K	tonB-dependent siderophore receptor
EXH44_04170	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
EXH44_04180	ENOG4108Z33	Thiol disulfide Interchange Protein
EXH44_04200	ENOG4105CJR	Integral membrane protein (MviN
EXH44_04205	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
EXH44_04215	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EXH44_04220	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EXH44_04225	ENOG4105HF0	Membrane
EXH44_04230	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EXH44_04240	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EXH44_04245	ENOG4105DHQ	Histidine kinase
EXH44_04250	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
EXH44_04255	ENOG4105DSJ	YicC domain protein
EXH44_04260	ENOG4105D4A	Cell wall formation (By similarity)
EXH44_04265	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
EXH44_04270	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EXH44_04275	ENOG4105F0N	pyrophosphate phospho-hydrolase
EXH44_04280	ENOG4105D0M	Protease HtpX homolog
EXH44_04285	ENOG4107QWE	)-transporter
EXH44_04315	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
EXH44_04335	ENOG4107XU6	Glycosyl transferase (Group 1
EXH44_04345	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EXH44_04355	ENOG4105CFG	Acts as a chaperone (By similarity)
EXH44_04360	ENOG4105VEQ	Cold shock protein
EXH44_04365	ENOG4105C31	Tryptophanyl-tRNA synthetase
EXH44_04370	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EXH44_04375	ENOG4105BZ4	penicillin-binding protein
EXH44_04380	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
EXH44_04395	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
EXH44_04400	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXH44_04405	ENOG4105QYV	Membrane
EXH44_04410	ENOG4105QYV	Membrane
EXH44_04415	ENOG4105K46	50S ribosomal protein l27
EXH44_04420	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EXH44_04425	ENOG4105CE4	GlcNAc 6-P deacetylase
EXH44_04430	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
EXH44_04435	ENOG4106H78	methyltransferase
EXH44_04440	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EXH44_04445	ENOG4105CAK	Cell division ATP-binding protein ftsE
EXH44_04450	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
EXH44_04455	ENOG4107QUT	magnesium and cobalt transport protein CorA
EXH44_04465	ENOG41063M6	Cell Division Protein
EXH44_04470	ENOG4107T0D	ABC, transporter
EXH44_04480	ENOG4108RCM	Nitroreductase
EXH44_04485	ENOG4105KZW	UPF0381 protein
EXH44_04490	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
EXH44_04500	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EXH44_04505	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
EXH44_04510	ENOG4107S2Z	UPF0761 membrane protein
EXH44_04515	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
EXH44_04520	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EXH44_04530	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EXH44_04575	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
EXH44_04580	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
EXH44_04590	ENOG4105CB5	ATP-dependent DNA helicase recG
EXH44_04595	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EXH44_04600	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
EXH44_04615	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EXH44_04620	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
EXH44_04635	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EXH44_04650	ENOG4108UW5	maltose o-acetyltransferase
EXH44_04670	ENOG4105JQN	Transcriptional regulator
EXH44_04680	ENOG4105EW9	transcriptional regulator AsnC family
EXH44_04685	ENOG410829K	Lysine exporter protein (Lyse ygga)
EXH44_04690	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EXH44_04705	ENOG4108RYK	Nad-dependent epimerase dehydratase
EXH44_04710	ENOG4105KVH	Transcriptional regulator
EXH44_04720	ENOG4105H4F	exported protein
EXH44_04730	ENOG4105CU9	asparagine synthetase A
EXH44_04735	ENOG4108VVK	transcriptional Regulator, AsnC
EXH44_04740	ENOG4108I5U	Uridine phosphorylase
EXH44_04745	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EXH44_04750	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EXH44_04755	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EXH44_04760	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EXH44_04765	ENOG4105C0P	Mg chelatase subunit ChlI
EXH44_04770	ENOG4107QRG	dna polymerase iii
EXH44_04785	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EXH44_04790	ENOG4105HHA	aminodeoxychorismate lyase
EXH44_04815	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
EXH44_04820	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
EXH44_04825	ENOG4108UM1	dedA family
EXH44_04835	ENOG4108K5P	(LipO)protein
EXH44_04845	ENOG4108R3E	Dna-3-methyladenine glycosylase i
EXH44_04855	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
EXH44_04860	ENOG41087AY	ADP-Ribose pyrophosphatase
EXH44_04885	ENOG4105F9E	Shikimate 5-dehydrogenase
EXH44_04890	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EXH44_04895	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EXH44_04900	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EXH44_04905	ENOG4105K5M	30s ribosomal protein S16
EXH44_04910	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
EXH44_04920	ENOG4108ZT0	50S ribosomal protein l17
EXH44_04925	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EXH44_04930	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EXH44_04935	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EXH44_04940	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXH44_04950	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EXH44_04955	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EXH44_04960	ENOG4105VPB	50S ribosomal protein L30
EXH44_04965	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EXH44_04970	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EXH44_04975	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EXH44_04980	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EXH44_04985	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EXH44_04990	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXH44_04995	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EXH44_05000	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EXH44_05010	ENOG4105EYW	Ion transport protein
EXH44_05015	ENOG4108W2W	
EXH44_05025	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EXH44_05030	ENOG41083MP	50s ribosomal protein l29
EXH44_05035	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EXH44_05040	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EXH44_05045	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EXH44_05050	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EXH44_05055	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXH44_05060	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EXH44_05065	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EXH44_05070	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EXH44_05085	ENOG4105C9Q	fumarate hydratase class II
EXH44_05090	ENOG4105C79	DNA protecting protein DprA
EXH44_05095	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EXH44_05100	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
EXH44_05105	ENOG4105C2J	ABC transporter
EXH44_05110	ENOG4107SDZ	Galactoside transport system permease protein mglC
EXH44_05125	ENOG4105C6Z	Gluconate
EXH44_05130	ENOG4105EXW	epimerase dehydratase
EXH44_05135	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
EXH44_05140	ENOG4105FB2	class II Aldolase
EXH44_05145	ENOG4105G63	Type III effector Hrp-dependent
EXH44_05150	ENOG4105ZXK	Dehydrogenase
EXH44_05155	ENOG4105MVE	transcriptional regulator
EXH44_05165	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
EXH44_05170	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
EXH44_05185	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
EXH44_05190	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
EXH44_05195	ENOG4105CEN	a g-specific adenine glycosylase
EXH44_05200	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
EXH44_05210	ENOG4105CI1	PTS System
EXH44_05215	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
EXH44_05220	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
EXH44_05240	ENOG4108K3A	Glutathione S-transferase
EXH44_05245	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EXH44_05255	ENOG4106YJS	accessory processing protein
EXH44_05265	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
EXH44_05275	ENOG4105VRX	Protein slyX homolog
EXH44_05280	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EXH44_05285	ENOG4105WWK	YheO domain protein
EXH44_05290	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
EXH44_05295	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
EXH44_05315	ENOG4105F9F	transposase
EXH44_05340	ENOG4108RVA	ribokinase
EXH44_05345	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EXH44_05350	ENOG4105CNN	ABC, transporter
EXH44_05355	ENOG4105C2J	ABC transporter
EXH44_05360	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
EXH44_05365	ENOG4105ETE	Transcriptional regulator (LacI family
EXH44_05380	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EXH44_05385	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EXH44_05390	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EXH44_05395	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EXH44_05400	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EXH44_05405	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EXH44_05410	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
EXH44_05420	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
EXH44_05430	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EXH44_05435	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
EXH44_05440	ENOG4107EDW	L-fucose operon activator
EXH44_05445	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
EXH44_05450	ENOG4105CMG	Carbohydrate kinase
EXH44_05455	ENOG4105NWF	RbsD or FucU transport
EXH44_05460	ENOG4107W7X	Aldolase
EXH44_05465	ENOG4105C2J	ABC transporter
EXH44_05470	ENOG4105CNN	ABC, transporter
EXH44_05475	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EXH44_05480	ENOG4105EDR	glucose galactose transporter
EXH44_05485	ENOG4105C0A	alcohol dehydrogenase
EXH44_05490	ENOG4105C26	Dehydrogenase
EXH44_05495	ENOG4105C26	Dehydrogenase
EXH44_05500	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
EXH44_05505	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
EXH44_05510	ENOG41077RS	Phosphatase
EXH44_05525	ENOG4108HPI	phosphatidate Cytidylyltransferase
EXH44_05530	ENOG4105DQ6	Transposase
EXH44_05535	ENOG4105IYK	transposase
EXH44_05540	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
EXH44_05545	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
EXH44_05550	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
EXH44_05555	ENOG4105CXY	transporter
EXH44_05560	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
EXH44_05565	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EXH44_05570	ENOG4105N1P	Ferredoxin-type protein
EXH44_05575	ENOG4108NEM	leader-binding protein dmsD
EXH44_05580	ENOG4107KGK	dmso reductase anchor subunit
EXH44_05585	ENOG4105QAX	Iron-sulfur
EXH44_05590	ENOG4107QY8	reductase
EXH44_05595	ENOG4105CIC	tryptophan-specific transport protein
EXH44_05600	ENOG4105C0F	tryptophanase EC 4.1.99.1
EXH44_05625	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
EXH44_05630	ENOG4105QTB	Flavodoxin
EXH44_05675	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXH44_05690	ENOG4105D16	lipopolysaccharide heptosyltransferase i
EXH44_05695	ENOG4105XA0	heptosyltransferase ii
EXH44_05705	ENOG4108UBT	opacity-associated protein
EXH44_05710	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
EXH44_05715	ENOG4105DJ4	phosphatidylserine decarboxylase
EXH44_05720	ENOG4107QX9	Thiol disulfide interChange protein
EXH44_05725	ENOG4108M1T	Cytochrome c-type biogenesis protein
EXH44_05730	ENOG4108M1T	Cytochrome c-type biogenesis protein
EXH44_05735	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
EXH44_05740	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
EXH44_05745	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
EXH44_05750	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EXH44_05760	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
EXH44_05770	ENOG4107RUZ	Sss sodium solute transporter superfamily
EXH44_05785	ENOG4105C4X	radical SAM domain protein
EXH44_05790	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EXH44_05795	ENOG410863D	Flavinator of succinate dehydrogenase
EXH44_05800	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
EXH44_05805	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EXH44_05810	ENOG4108YZA	Nitrogen regulatory protein pii
EXH44_05815	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EXH44_05820	ENOG4105WD1	Membrane
EXH44_05825	ENOG4105K64	Glycosyl transferase, family 2
EXH44_05830	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
EXH44_05835	ENOG4105RX8	Protein of unknown function (DUF1523)
EXH44_05840	ENOG4105F8V	Hydrolase, tatD family
EXH44_05845	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
EXH44_05850	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EXH44_05855	ENOG4105DCF	alanine dehydrogenase
EXH44_05860	ENOG4105C8J	)-transporter
EXH44_05870	ENOG4105PM1	preprotein translocase subunit SecE
EXH44_05875	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
EXH44_05880	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EXH44_05885	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EXH44_05890	ENOG4108VZM	50s ribosomal protein L10
EXH44_05895	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EXH44_05900	ENOG4105XMH	SpoVT AbrB domain protein
EXH44_05905	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
EXH44_05920	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EXH44_05930	ENOG4105KA0	thioesterase Superfamily protein
EXH44_05935	ENOG4105CQB	FAD linked oxidase domain protein
EXH44_05940	ENOG4105W44	ompa motb domain protein
EXH44_05950	ENOG4105W44	ompa motb domain protein
EXH44_05955	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
EXH44_05960	ENOG4105DAN	ATP-dependent protease
EXH44_05965	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
EXH44_05990	ENOG4105DSY	exodeoxyribonuclease V, gamma
EXH44_05995	ENOG4107QXK	peptidase
EXH44_06005	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
EXH44_06020	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EXH44_06030	ENOG4105VG0	50S ribosomal protein l34
EXH44_06035	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EXH44_06040	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
EXH44_06045	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
EXH44_06065	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EXH44_06070	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EXH44_06075	ENOG4105C1A	potassium transporter peripheral membrane
EXH44_06080	ENOG4105DJV	ribulose-phosphate 3-epimerase
EXH44_06085	ENOG4105NRA	50s ribosomal protein l31 type b
EXH44_06090	ENOG4105YK5	50S ribosomal protein L36
EXH44_06105	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
EXH44_06110	ENOG4108BGM	Quinol dehydrogenase periplasmic component
EXH44_06115	ENOG4105GXZ	Ferredoxin-type protein NapH
EXH44_06120	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
EXH44_06125	ENOG4105CUW	cytochrome C-TYPE protein
EXH44_06130	ENOG4105DIQ	Transcriptional regulator
EXH44_06135	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
EXH44_06140	ENOG4105C6Z	Gluconate
EXH44_06145	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
EXH44_06150	ENOG4108URH	decarboxylase
EXH44_06160	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
EXH44_06165	ENOG4105D98	threonine synthase
EXH44_06170	ENOG410667J	hydrolase
EXH44_06175	ENOG4105CXY	transporter
EXH44_06205	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
EXH44_06220	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
EXH44_06225	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
EXH44_06255	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EXH44_06260	ENOG4105EM7	Selenocysteine-specific translation elongation factor
EXH44_06265	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
EXH44_06275	ENOG4105DFP	Integrase
EXH44_06360	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
EXH44_06365	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EXH44_06370	ENOG4105CJN	penicillin-binding protein
EXH44_06375	ENOG4105CNI	cell division protein FtsW
EXH44_06380	ENOG4105K6T	rare lipoprotein A
EXH44_06385	ENOG4105DZ1	carboxypeptidase
EXH44_06405	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EXH44_06410	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EXH44_06415	ENOG41076CZ	activating enzyme
EXH44_06420	ENOG4105G0K	glycine radical enzyme YjjI family
EXH44_06430	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EXH44_06435	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EXH44_06440	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EXH44_06450	ENOG4107RM6	sulfurtransferase
EXH44_06455	ENOG4107RM6	sulfurtransferase
EXH44_06460	ENOG4105CUC	YeeE YedE family protein
EXH44_06465	ENOG4105EKQ	RNA-directed DNA polymerase
EXH44_06470	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EXH44_06475	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EXH44_06480	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EXH44_06485	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EXH44_06495	ENOG4108YZA	Nitrogen regulatory protein pii
EXH44_06500	ENOG4105BZU	Histidine kinase
EXH44_06505	ENOG4105C9K	Endothelin-converting enzyme 1
EXH44_06520	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
EXH44_06525	ENOG4108WFC	UPF0438 protein yifE
EXH44_06530	ENOG4108EKI	Dehydrogenase
EXH44_06535	ENOG4105W0E	50S ribosomal protein L33
EXH44_06545	ENOG4105W5Q	DNA repair protein (RadC
EXH44_06550	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EXH44_06570	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
EXH44_06575	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
EXH44_06580	ENOG4105YP7	UPF0270 protein
EXH44_06585	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
EXH44_06590	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EXH44_06595	ENOG4105C37	(CBS) domain
EXH44_06600	ENOG4105HYY	HAD superfamily (Subfamily IF) hydrolase, YfhB
EXH44_06605	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
EXH44_06615	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EXH44_06625	ENOG4105C2D	reductase
EXH44_06630	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EXH44_06640	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EXH44_06655	ENOG41090HT	Inherit from COG: transposase
EXH44_06660	ENOG4105CJ1	ABC, transporter
EXH44_06665	ENOG4108KYE	ABC-2 type transporter
EXH44_06715	ENOG41090VV	Protein of unknown function (DUF2846)
EXH44_06760	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
EXH44_06775	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
EXH44_06785	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
EXH44_06790	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EXH44_06795	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EXH44_06800	ENOG41090ED	Protein with unknown function (DUF469)
EXH44_06805	ENOG4108VIA	integral membrane protein
EXH44_06810	ENOG4105VZ9	UPF0235 protein
EXH44_06815	ENOG4106KVJ	cytochrome C assembly protein
EXH44_06820	ENOG4108JU6	CBS domain protein
EXH44_06825	ENOG4105EAH	synthase
EXH44_06830	ENOG4105WPN	DNA integration recombination invertion protein
EXH44_06840	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EXH44_06845	ENOG4105CHR	reductase
EXH44_06850	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
EXH44_06855	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EXH44_06860	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
EXH44_06865	ENOG4105C8U	phosphate abc transporter
EXH44_06870	ENOG4105E2Z	phosphate ABC transporter (Permease
EXH44_06875	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EXH44_06915	ENOG4105EMU	Dehydrogenase
EXH44_06930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EXH44_06935	ENOG4105BZU	Histidine kinase
EXH44_06940	ENOG4108EQA	pts system
EXH44_06945	ENOG4105ETZ	PTS System
EXH44_06950	ENOG4105F3R	pts system mannose fructose sorbose family iid
EXH44_06960	ENOG4108ETH	Formylglycinamide ribotide synthetase
EXH44_06965	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
EXH44_06970	ENOG4107RUE	extracellular solute-binding protein family 1
EXH44_06990	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
EXH44_06995	ENOG4105E33	succinate dehydrogenase
EXH44_07000	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
EXH44_07005	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
EXH44_07010	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EXH44_07015	ENOG4107YB6	acetyltransferase, (GNAT) family
EXH44_07025	ENOG4105MYG	DNA polymerase iii, chi subunit
EXH44_07030	ENOG4106678	morphogenetic protein associated with SpoVID
EXH44_07035	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EXH44_07040	ENOG4107YZP	Rhodanese domain protein
EXH44_07045	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
EXH44_07050	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EXH44_07055	ENOG4105D7W	serine acetyltransferase
EXH44_07080	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EXH44_07085	ENOG4105ESV	Glycosyl transferase, family 4
EXH44_07095	ENOG4108WJ1	acetyltransferase
EXH44_07100	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EXH44_07115	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
EXH44_07165	ENOG4105DEF	Extracellular solute-binding protein, family 5
EXH44_07175	ENOG4105DFU	Cell wall formation (By similarity)
EXH44_07185	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
EXH44_07195	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EXH44_07205	ENOG4105KUZ	arsenate reductase
EXH44_07210	ENOG4105CAH	Chromate
EXH44_07215	ENOG4105EEI	dihydropteroate synthase
EXH44_07225	ENOG4105EI2	Pseudouridine synthase
EXH44_07235	ENOG4105C03	ribonuclease
EXH44_07250	ENOG4105D7K	pfkb domain protein
EXH44_07260	ENOG4105WBN	Transcriptional regulator (LacI family
EXH44_07265	ENOG4105C8J	)-transporter
EXH44_07275	ENOG4105K5B	UPF0225 protein
EXH44_07280	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EXH44_07285	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
EXH44_07290	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
EXH44_07295	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
EXH44_07300	ENOG4105D52	delta-aminolevulinic acid dehydratase
EXH44_07305	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EXH44_07310	ENOG410804X	Transcriptional regulator
EXH44_07315	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EXH44_07320	ENOG4105KQC	Competence protein
EXH44_07325	ENOG4108IA2	Sodium pantothenate symporter
EXH44_07330	ENOG4105RG0	Membrane
EXH44_07335	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
EXH44_07340	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EXH44_07345	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EXH44_07350	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EXH44_07355	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EXH44_07360	ENOG4105CEM	UPF0597 protein
EXH44_07375	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
EXH44_07385	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
EXH44_07405	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
EXH44_07420	ENOG4107RK2	ADP-ribose diphosphatase NudE
EXH44_07425	ENOG4105W39	Membrane
EXH44_07430	ENOG4105TMB	Formate nitrite transporter
EXH44_07435	ENOG4105C6N	Formate acetyltransferase
EXH44_07440	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EXH44_07445	ENOG4105F1A	Pyruvate formate-lyase
EXH44_07455	ENOG4107TT5	NLP P60 protein
EXH44_07460	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
EXH44_07465	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
EXH44_07470	ENOG4105CBC	glutamate synthase
EXH44_07475	ENOG4105BZ8	glutamate synthase
EXH44_07480	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EXH44_07485	ENOG4105C2I	pirin domain protein
EXH44_07490	ENOG4105EX9	Membrane
EXH44_07495	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EXH44_07505	ENOG41065U4	response regulator
EXH44_07510	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
EXH44_07515	ENOG4108IPJ	Membrane
EXH44_07520	ENOG4107ZVW	dihydroneopterin aldolase
EXH44_07525	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EXH44_07530	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
EXH44_07535	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
EXH44_07540	ENOG4105D9N	nucleoside
EXH44_07545	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
EXH44_07555	ENOG41061ZR	Transcriptional regulator
EXH44_07560	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EXH44_07590	ENOG4107T0K	Adenylate cyclase
EXH44_07595	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
EXH44_07600	ENOG4105DA4	cytochrome c-type biogenesis protein
EXH44_07605	ENOG4107QX9	Thiol disulfide interChange protein
EXH44_07610	ENOG4108DMF	Cytochrome C biogenesis protein
EXH44_07615	ENOG4108DMF	Cytochrome C biogenesis protein
EXH44_07625	ENOG4107UWN	reductase
EXH44_07630	ENOG4105XW2	UPF0263 protein
EXH44_07640	ENOG41090EX	DsrE family
EXH44_07645	ENOG4105W49	UPF0434 protein
EXH44_07650	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
EXH44_07655	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EXH44_07660	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EXH44_07665	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
EXH44_07670	ENOG41090FY	type IV pilus biogenesis stability protein PilW
EXH44_07710	ENOG4108ST3	glycosyltransferase
EXH44_07720	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EXH44_07725	ENOG4105KPV	Transcriptional regulator
EXH44_07730	ENOG4105CGY	Dna recombination protein
EXH44_07735	ENOG4105DDQ	anthranilate synthase
EXH44_07745	ENOG4105PGM	cation diffusion facilitator family transporter
EXH44_07750	ENOG4105PGM	cation diffusion facilitator family transporter
EXH44_07755	ENOG4105CRQ	synthase (Component I)
EXH44_07765	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EXH44_07770	ENOG4105Y3E	Modulates RecA activity (By similarity)
EXH44_07775	ENOG41060QA	UPF0267 protein
EXH44_07780	ENOG4108WI1	Dna topoisomerase
EXH44_07790	ENOG4105E2X	shikimate dehydrogenase
EXH44_07815	ENOG4105W0Z	cytoplasmic protein
EXH44_07820	ENOG4107QP8	phosphohexose isomerase
EXH44_07830	ENOG4105C8V	SAICAR synthetase
EXH44_07840	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
EXH44_07845	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EXH44_07855	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EXH44_07860	ENOG4105NX3	Membrane
EXH44_07875	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EXH44_07880	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
EXH44_07885	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EXH44_07890	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EXH44_07895	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EXH44_07905	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EXH44_07910	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EXH44_07915	ENOG4105DA4	cytochrome c-type biogenesis protein
EXH44_07920	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
EXH44_07925	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
EXH44_07930	ENOG4105CNT	hydrolase family 2
EXH44_07935	ENOG4106NDP	Transcriptional regulator
EXH44_07940	ENOG4105CR8	Transcriptional regulator
EXH44_07945	ENOG4105MGM	doxx family
EXH44_07960	ENOG4105D6J	arsenicaL-resistance protein
EXH44_07965	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EXH44_07975	ENOG4105F9F	transposase
EXH44_07980	ENOG4105DIK	(ABC) transporter
EXH44_07985	ENOG4105CC5	ABC transporter
EXH44_07990	ENOG4105CC5	ABC transporter
EXH44_07995	ENOG4107QI1	Mate efflux family protein
EXH44_08000	ENOG4105D3G	Pseudouridine synthase
EXH44_08005	ENOG4107T9Q	phosphonate abc transporter
EXH44_08015	ENOG4105D5T	phosphonate abc transporter
EXH44_08025	ENOG4105S7S	phosphonate abc transporter
EXH44_08045	ENOG4105E07	UPF0149 protein
EXH44_08060	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EXH44_08065	ENOG4105C5I	Dehydrogenase
EXH44_08070	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EXH44_08075	ENOG4105D60	lipoprotein releasing system transmembrane protein
EXH44_08080	ENOG4108VW9	Membrane
EXH44_08085	ENOG4105E0X	reductase
EXH44_08090	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
EXH44_08095	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EXH44_08100	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EXH44_08105	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EXH44_08110	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EXH44_08115	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EXH44_08120	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
EXH44_08125	ENOG4105CJ2	(LipO)protein
EXH44_08135	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EXH44_08140	ENOG4105CTQ	phosphohexokinase
EXH44_08145	ENOG4105C9B	Cysteine desulfurase
EXH44_08155	ENOG4105K3M	)-transporter
EXH44_08160	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
EXH44_08165	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
EXH44_08175	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EXH44_08180	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
EXH44_08185	ENOG4105C5Y	PTS System
EXH44_08190	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
EXH44_08195	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
EXH44_08200	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EXH44_08205	ENOG4105EEQ	Na H antiporter
EXH44_08210	ENOG4105EIN	peptidylprolyl cis-trans isomerase
EXH44_08215	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EXH44_08220	ENOG4108R6K	riboflavin synthase, subunit alpha
EXH44_08230	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EXH44_08235	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
EXH44_08240	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EXH44_08245	ENOG4105DQF	Hydrolase
EXH44_08250	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
EXH44_08255	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EXH44_08260	ENOG4105XQ6	frataxin-like protein
EXH44_08265	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EXH44_08270	ENOG4109045	doxx family
EXH44_08280	ENOG4105E18	UPF0276 protein
EXH44_08285	ENOG4105F9F	transposase
EXH44_08295	ENOG4105F9F	transposase
EXH44_08310	ENOG4108WQI	RNA Polymerase
EXH44_08320	ENOG4105E55	glycerol-3-phosphate acyltransferase
EXH44_08325	ENOG4105C09	Bile acid
EXH44_08335	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
EXH44_08360	ENOG4105DP9	ABC transporter
EXH44_08365	ENOG4105C9A	Phoh family
EXH44_08370	ENOG4105D9R	oxidoreductase
EXH44_08375	ENOG4105C2W	permease
EXH44_08385	ENOG4105C7N	Xanthine uracil vitamin C permease
EXH44_08390	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EXH44_08395	ENOG4108Z66	YbaK ebsC protein
EXH44_08405	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EXH44_08410	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
EXH44_08420	ENOG4105DGW	oligopeptidase A
EXH44_08430	ENOG4105CQC	Prephenate dehydratase
EXH44_08435	ENOG4108R99	pseudouridine synthase
EXH44_08440	ENOG4105CMR	udp-glucose 4-epimerase
EXH44_08445	ENOG4105EYM	Major Facilitator superfamily
EXH44_08450	ENOG4105C1J	atp-dependent rna helicase
EXH44_08455	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
EXH44_08470	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EXH44_08475	ENOG4105C3G	gtp-binding protein
EXH44_08500	ENOG4105UGU	tonB-dependent Receptor
EXH44_08505	ENOG4107RN3	metallophosphoesterase
EXH44_08510	ENOG4105CH6	catalase
EXH44_08530	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EXH44_08535	ENOG4108IJ9	(ABC) transporter
EXH44_08550	ENOG4106N3A	copper homeostasis protein cutc
EXH44_08555	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
EXH44_08560	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
EXH44_08565	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
EXH44_08570	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EXH44_08575	ENOG4107QX8	SPFH domain, Band 7 family protein
EXH44_08595	ENOG4105C25	Primosomal protein n'
EXH44_08600	ENOG4108NIW	Leucine export protein LeuE
EXH44_08605	ENOG4105DTR	rard protein
EXH44_08610	ENOG4105DTR	rard protein
EXH44_08615	ENOG4105CHM	Aminotransferase
EXH44_08620	ENOG4105E4F	Isochorismate synthase
EXH44_08625	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
EXH44_08630	ENOG4105E1F	short-chain dehydrogenase reductase
EXH44_08635	ENOG4105DWU	Membrane
EXH44_08640	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EXH44_08645	ENOG4105D0M	Protease HtpX homolog
EXH44_08650	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
EXH44_08660	ENOG4105CH2	amidohydrolase
EXH44_08670	ENOG4105EX9	Membrane
EXH44_08675	ENOG4105DSF	transport protein
EXH44_08685	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EXH44_08690	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EXH44_08695	ENOG4105EPW	hflc protein
EXH44_08700	ENOG4107QJR	hflk protein
EXH44_08715	ENOG4105K63	Thioredoxin
EXH44_08720	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EXH44_08725	ENOG4105C8P	)-transporter
EXH44_08730	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
EXH44_08735	ENOG4105K8N	protein family UPF0079, ATPase
EXH44_08740	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
EXH44_08745	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EXH44_08750	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
EXH44_08755	ENOG4105C0B	DNA polymerase III (alpha subunit)
EXH44_08760	ENOG4108K5H	permease YjgP YjgQ family protein
EXH44_08765	ENOG4108M8S	permease YjgP YjgQ family protein
EXH44_08770	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EXH44_08775	ENOG4105CFP	Peptidase U32
EXH44_08780	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXH44_08790	ENOG4107QKW	extracellular solute-binding protein family 1
EXH44_08795	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EXH44_08810	ENOG4105PGM	cation diffusion facilitator family transporter
EXH44_08815	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
EXH44_08820	ENOG4105DGN	Electron transport complex
EXH44_08825	ENOG4108R3D	Electron transport complex
EXH44_08830	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
EXH44_08835	ENOG4105EN6	Membrane
EXH44_08840	ENOG4105D6A	Electron transport complex
EXH44_08855	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
EXH44_08860	ENOG4105DMQ	Methyltransferase
EXH44_08865	ENOG4105CEP	NADH dehydrogenase
EXH44_08870	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EXH44_08875	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EXH44_08880	ENOG41082NX	50s ribosomal protein l35
EXH44_08885	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EXH44_08895	ENOG4105CIN	aminoacyl-histidine dipeptidase
EXH44_08900	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
EXH44_08905	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EXH44_08910	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EXH44_08915	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
EXH44_08920	ENOG41080C8	DUF218 domain
EXH44_08925	ENOG4108ZPC	Polysaccharide pyruvyl transferase
EXH44_08930	ENOG4105F0R	Cytidylyltransferase
EXH44_08935	ENOG4108MY6	biosynthesis protein
EXH44_08940	ENOG4105P7J	Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide
EXH44_08945	ENOG41068D6	Glycosyltransferase
EXH44_08955	ENOG4108RJ9	Glycosyl transferase, family 2
EXH44_08960	ENOG4108RYC	glycosyltransferase
EXH44_08965	ENOG4108Z03	MAF-like protein
EXH44_08970	ENOG4105DJF	DNA polymerase III, delta' subunit
EXH44_08980	ENOG4105C8T	Leucyl-tRNA synthetase
EXH44_08990	ENOG4105CUC	YeeE YedE family protein
EXH44_08995	ENOG4105C22	threonyL-tRNA synthetase
EXH44_09005	ENOG4105M2J	Glutaredoxin
EXH44_09010	ENOG4105C5H	ABC transporter
EXH44_09015	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EXH44_09020	ENOG4105C34	Pseudouridine synthase
EXH44_09025	ENOG4108VTV	Inherit from NOG: Membrane
EXH44_09030	ENOG4108JQ5	ABC transporter
EXH44_09035	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EXH44_09040	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EXH44_09045	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
EXH44_09050	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
EXH44_09060	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
EXH44_09070	ENOG4105E9S	glutaredoxin 2
EXH44_09080	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
EXH44_09090	ENOG4105M15	transport protein ExbD
EXH44_09095	ENOG4105M8K	biopolymer transport protein
EXH44_09100	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
EXH44_09105	ENOG4105ERU	peptidase
EXH44_09110	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EXH44_09115	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
EXH44_09125	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
EXH44_09130	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
EXH44_09135	ENOG4105EE5	Membrane protein terC
EXH44_09145	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
EXH44_09150	ENOG4108IJ0	Aspartate ammonia-lyase
EXH44_09155	ENOG4105WXI	Bacterial OB fold (BOF) protein
EXH44_09160	ENOG4105WXI	Bacterial OB fold (BOF) protein
EXH44_09165	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EXH44_09170	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EXH44_09175	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
EXH44_09180	ENOG4105DJ0	Poly(A) Polymerase
EXH44_09185	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXH44_09190	ENOG4105C5H	ABC transporter
EXH44_09195	ENOG4105CUZ	uba thif-type nad fad binding protein
EXH44_09205	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
EXH44_09210	ENOG4105D6S	protein involved in catabolism of external DNA
EXH44_09215	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EXH44_09220	ENOG4105BZW	Glycerate kinase
EXH44_09225	ENOG4108JJB	ABC transporter
EXH44_09230	ENOG4105C7J	ABC transporter, permease
EXH44_09240	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EXH44_09250	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EXH44_09255	ENOG4108Q67	UPF0319 protein
EXH44_09260	ENOG4108JU5	Magnesium and cobalt efflux protein
EXH44_09265	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
EXH44_09270	ENOG4105EMN	RNA polymerase sigma factor
EXH44_09275	ENOG41069PW	sigma-e factor negative regulatory protein
EXH44_09280	ENOG4105I7R	Adenylate cyclase
EXH44_09300	ENOG4105DR9	pseudouridine synthase
EXH44_09305	ENOG4105WP7	tRNA pseudouridine synthase C
EXH44_09310	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EXH44_09315	ENOG4105DVT	helicase
EXH44_09320	ENOG4105VAW	lrga family
EXH44_09325	ENOG41067MG	lrgb family
EXH44_09335	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EXH44_09340	ENOG4105ECY	inositol monophosphatase
EXH44_09345	ENOG4105EIB	trna rrna methyltransferase
EXH44_09370	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
EXH44_09375	ENOG4105E0C	molybdate abc transporter
EXH44_09380	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
EXH44_09385	ENOG4105F4R	Transcriptional regulator mode
EXH44_09390	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EXH44_09420	ENOG41090HT	Inherit from COG: transposase
EXH44_09425	ENOG4105C3R	Methionine synthase
EXH44_09460	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EXH44_09465	ENOG4105C3F	Signal peptidase i
EXH44_09470	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EXH44_09475	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
EXH44_09485	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
EXH44_09490	ENOG4105DWV	Homoserine O-trans-acetylase
EXH44_09495	ENOG4105E7U	AraC family transcriptional regulator
EXH44_09500	ENOG4107KGK	dmso reductase anchor subunit
EXH44_09505	ENOG4105QAX	Iron-sulfur
EXH44_09510	ENOG4107QY8	reductase
EXH44_09515	ENOG4108SXK	Transporter Drug Metabolite Exporter family
EXH44_09520	ENOG4107GZ4	SanA protein
EXH44_09525	ENOG4107S6Z	Na H antiporter
EXH44_09535	ENOG4108SAU	DNA-binding protein H-ns
EXH44_09540	ENOG4105CIY	formyltetrahydrofolate deformylase
EXH44_09545	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EXH44_09550	ENOG4105DEF	Extracellular solute-binding protein, family 5
EXH44_09565	ENOG4108JQ7	(ABC) transporter
EXH44_09570	ENOG4108IYU	L-aspartate oxidase
EXH44_09575	ENOG4105E96	Colicin v production protein
EXH44_09580	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EXH44_09590	ENOG4105CHU	acetyl-coa acetyltransferase
EXH44_09605	ENOG4105DDY	UPF0142 protein ycaO
EXH44_09610	ENOG4105C03	ribonuclease
EXH44_09615	ENOG4107RUE	extracellular solute-binding protein family 1
EXH44_09625	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
EXH44_09630	ENOG4108IUZ	ABC transporter
EXH44_09635	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
EXH44_09640	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
EXH44_09645	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EXH44_09660	ENOG4105XCT	Protein of unknown function (DUF2489)
EXH44_09665	ENOG4105D4P	Coproporphyrinogen iii oxidase
EXH44_09670	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
EXH44_09675	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
EXH44_09680	ENOG4105CFH	Aspartokinase
EXH44_09685	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EXH44_09690	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
EXH44_09695	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EXH44_09700	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
EXH44_09735	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EXH44_09760	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EXH44_09765	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EXH44_09780	ENOG4108QD6	
EXH44_09795	ENOG41065CD	Exported protein
EXH44_09800	ENOG4105D7X	high-affinity nickel-transporter
EXH44_09805	ENOG4105BZG	amino acid carrier protein
EXH44_09810	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EXH44_09820	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
EXH44_09830	ENOG4105CM6	amino acid regulated cytosolic protein
EXH44_09835	ENOG4105D0A	hydroxylase
EXH44_09840	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
EXH44_09845	ENOG4108Z1B	Cyclase dehydrase
EXH44_09855	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EXH44_09860	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EXH44_09865	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EXH44_09870	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EXH44_09880	ENOG4105D06	uba thif-type nad fad binding protein
EXH44_09885	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EXH44_09890	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
EXH44_09895	ENOG4105C5H	ABC transporter
EXH44_09910	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
EXH44_09915	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
EXH44_09920	ENOG4105KME	endoribonuclease L-psp
EXH44_09925	ENOG4106V8H	Nucleoid-associated protein
EXH44_09930	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EXH44_09935	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
EXH44_09940	ENOG4108IJ1	Dehydrogenase
EXH44_09945	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EXH44_09950	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
EXH44_09955	ENOG4107SC1	transglycosylase
EXH44_09960	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
EXH44_09975	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EXH44_09980	ENOG4105D6U	Sodium Glutamate Symporter
EXH44_09985	ENOG4105D0C	transport protein
EXH44_09995	ENOG4105CWC	Acetylornithine deacetylase
EXH44_10005	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EXH44_10010	ENOG4108RE7	deoxyribonuclease
EXH44_10015	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EXH44_10025	ENOG4105E4P	ATPase (AAA
EXH44_10035	ENOG4105F5P	DNA-damage-inducible protein d
EXH44_10060	ENOG4105DZR	Type I site-specific deoxyribonuclease
EXH44_10070	ENOG4105E4P	ATPase (AAA
EXH44_10085	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
EXH44_10100	ENOG4105E9K	Isocitrate dehydrogenase
EXH44_10105	ENOG4108MN8	Membrane
EXH44_10110	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
EXH44_10115	ENOG4105DKP	glycosyl transferase, family 9
EXH44_10120	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EXH44_10125	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
EXH44_10130	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EXH44_10135	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EXH44_10140	ENOG4105C2C	drug resistance transporter, Bcr CflA
EXH44_10145	ENOG4105I08	Pseudouridine synthase
EXH44_10150	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
EXH44_10155	ENOG4107TSG	Extracellular solute-binding protein, family 5
EXH44_10160	ENOG4105D1F	ATP-binding protein
EXH44_10165	ENOG4108ZPB	UPF0306 protein
EXH44_10170	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EXH44_10175	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
EXH44_10180	ENOG4105D3Y	Na H antiporter
EXH44_10185	ENOG4105CGK	Exodeoxyribonuclease III
EXH44_10190	ENOG4105E0U	tyrosine-specific transport protein
EXH44_10195	ENOG4105EW9	transcriptional regulator AsnC family
EXH44_10200	ENOG4105CNU	cell division protein FtsK
EXH44_10205	ENOG4105CGZ	zinc metallopeptidase
EXH44_10210	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EXH44_10215	ENOG41072GX	Peptidase M22 Glycoprotease
EXH44_10220	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EXH44_10225	ENOG4105CE9	30S ribosomal protein S2
EXH44_10230	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EXH44_10235	ENOG4105BZS	acriflavin resistance protein
EXH44_10240	ENOG410624X	efflux transporter, rnd family, mfp subunit
EXH44_10245	ENOG4105Y7M	Transcriptional regulator, TetR family
EXH44_10250	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EXH44_10275	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EXH44_10280	ENOG4108UUM	single-stranded DNA-binding protein
EXH44_10315	ENOG4105W1Y	Transcriptional regulator
EXH44_10325	ENOG4108Z6Z	Transcriptional regulator
EXH44_10350	ENOG4107STQ	Multicopper oxidase
EXH44_10375	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EXH44_10380	ENOG4105GR3	Histidine kinase
EXH44_10425	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EXH44_10430	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
EXH44_10435	ENOG41077A9	carbonic anhydrase
EXH44_10440	ENOG4105VEQ	Cold shock protein
EXH44_10450	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
EXH44_10455	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
EXH44_10460	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
EXH44_10475	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
EXH44_10480	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
EXH44_10485	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
EXH44_10490	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EXH44_10495	ENOG4105C28	cystathionine
EXH44_10500	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EXH44_10505	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EXH44_10510	ENOG4105C7S	Dehydrogenase
EXH44_10515	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EXH44_10520	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
EXH44_10525	ENOG4105DBI	uridine monophosphokinase
EXH44_10530	ENOG4105DHP	deoxycytidine triphosphate deaminase
EXH44_10535	ENOG4105E0U	tyrosine-specific transport protein
EXH44_10560	ENOG4105CJ3	phosphate transporter
EXH44_10565	ENOG4107IX6	phosphate transport regulator
EXH44_10575	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EXH44_10580	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EXH44_10585	ENOG4108QBX	(LipO)protein
EXH44_10590	ENOG4108VD1	dedA family
EXH44_10595	ENOG4105ETE	Transcriptional regulator (LacI family
EXH44_10600	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
EXH44_10605	ENOG4105CA3	membrane-bound lytic murein transglycosylase
EXH44_10620	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EXH44_10625	ENOG4105DBV	ornithine carbamoyltransferase
EXH44_10630	ENOG4105C1J	atp-dependent rna helicase
EXH44_10635	ENOG4105D7A	ATP-binding protein
EXH44_10640	ENOG4105C4Y	ABC transporter
EXH44_10645	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
EXH44_10650	ENOG4108QD1	Membrane
EXH44_10660	ENOG4108QD1	Membrane
EXH44_10665	ENOG4105E68	Sulfatase
EXH44_10670	ENOG4105PAN	UPF0352 protein
EXH44_10675	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
EXH44_10680	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EXH44_10690	ENOG4105NSG	hemerythrin hhe cation binding domain protein
EXH44_10695	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EXH44_10705	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EXH44_10710	ENOG4107RCV	ABC transporter, permease
EXH44_10715	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EXH44_10720	ENOG4105TWJ	Domain of unknown function (DUF1919)
EXH44_10730	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EXH44_10735	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
EXH44_10740	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
EXH44_10745	ENOG4108ESZ	Glycogen debranching enzyme
EXH44_10755	ENOG4105C8Y	Acetylornithine aminotransferase
EXH44_10770	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EXH44_10785	ENOG4105C2M	dna polymerase I
EXH44_10790	ENOG4108ZP8	Acetolactate synthase small subunit
EXH44_10795	ENOG4105C7K	acetolactate synthase
EXH44_10800	ENOG4105C6K	Malic enzyme
EXH44_10820	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EXH44_10835	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
EXH44_10840	ENOG4105CHV	Transcription elongation factor NusA
EXH44_10845	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EXH44_10850	ENOG4105FP6	Protein of unknown function (DUF3302)
EXH44_10855	ENOG4105EFX	secretion protein, HlyD family
EXH44_10860	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
EXH44_10865	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EXH44_10870	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EXH44_10875	ENOG4105CVE	Lytic murein transglycosylase
EXH44_10880	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
EXH44_10885	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
EXH44_10890	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EXH44_10895	ENOG4108UJD	30S ribosomal protein S9
EXH44_10900	ENOG4105EKQ	RNA-directed DNA polymerase
EXH44_10905	ENOG4105D1Q	UPF0246 protein
EXH44_10915	ENOG41076HS	cation diffusion facilitator family transporter
EXH44_10920	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
EXH44_10925	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EXH44_10930	ENOG4105C5S	asparaginyl-tRNA synthetase
EXH44_10935	ENOG4105C9X	ppx gppa phosphatase
EXH44_10980	ENOG4108R66	Conserved Protein
EXH44_10985	ENOG4105QEK	Transcriptional regulator
EXH44_10990	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)