locus-tag	class	description
PE794_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PE794_00010	COG0592	DNA-directed DNA polymerase activity
PE794_00025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PE794_00040	COG0616	signal peptide processing
PE794_00055	COG3116	cell division
PE794_00060	COG0768	penicillin binding
PE794_00065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PE794_00070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PE794_00080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PE794_00085	COG0772	Belongs to the SEDS family
PE794_00095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PE794_00100	COG1181	Belongs to the D-alanine--D-alanine ligase family
PE794_00110	COG0849	cell division
PE794_00115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PE794_00120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PE794_00125	COG0497	DNA recombination
PE794_00130	COG4172	Belongs to the ABC transporter superfamily
PE794_00135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE794_00140	COG0601	transmembrane transport
PE794_00165	COG0193	aminoacyl-tRNA hydrolase activity
PE794_00170	COG0012	GTP binding
PE794_00175	COG2020	methyltransferase activity
PE794_00185	COG3133	Outer membrane lipoprotein
PE794_00190	COG3102	Protein conserved in bacteria
PE794_00195	COG0018	arginyl-trna synthetase
PE794_00210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PE794_00215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PE794_00220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PE794_00225	COG0196	riboflavin kinase activity
PE794_00230	COG3172	ATPase kinase involved in NAD metabolism
PE794_00235	COG2129	metallophosphoesterase
PE794_00240	COG0745	RESPONSE REGULATOR receiver
PE794_00250	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PE794_00255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PE794_00270	COG1217	gtp-binding protein TYPA
PE794_00275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PE794_00285	COG1561	YicC-like family, N-terminal region
PE794_00290	COG0354	folic acid binding
PE794_00295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PE794_00300	COG2197	response regulator
PE794_00310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PE794_00345	COG0747	negative chemotaxis
PE794_00350	COG0747	negative chemotaxis
PE794_00355	COG0601	transmembrane transport
PE794_00360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PE794_00365	COG0444	Belongs to the ABC transporter superfamily
PE794_00370	COG4608	Belongs to the ABC transporter superfamily
PE794_00385	COG0251	oxidation-reduction process
PE794_00390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PE794_00395	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PE794_00400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PE794_00405	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PE794_00410	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PE794_00415	COG0848	biopolymer transport protein
PE794_00420	COG0811	peptide transport
PE794_00425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PE794_00430	COG3118	belongs to the thioredoxin family
PE794_00435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PE794_00435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PE794_00435	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
PE794_00440	COG1461	Dihydroxyacetone kinase
PE794_00445	COG2376	Dihydroxyacetone kinase
PE794_00450	COG0492	ferredoxin-NADP+ reductase activity
PE794_00455	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PE794_00460	COG3753	Protein conserved in bacteria
PE794_00480	COG3030	protein affecting phage T7 exclusion by the F plasmid
PE794_00485	COG0006	proline dipeptidase activity
PE794_00495	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
PE794_00515	COG0129	dihydroxy-acid dehydratase activity
PE794_00520	COG3978	acetolactate synthase activity
PE794_00535	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
PE794_00540	COG0437	4 iron, 4 sulfur cluster binding
PE794_00545	COG3301	Polysulphide reductase, NrfD
PE794_00555	COG5295	Hep Hag repeat protein
PE794_00555	COG5295	Hep Hag repeat protein
PE794_00555	COG5295	Hep Hag repeat protein
PE794_00570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PE794_00575	COG1414	Transcriptional regulator
PE794_00580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PE794_00590	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PE794_00600	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PE794_00605	COG3068	Protein conserved in bacteria
PE794_00630	COG1278	Cold shock
PE794_00635	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
PE794_00640	COG0793	Belongs to the peptidase S41A family
PE794_00645	COG2989	Protein conserved in bacteria
PE794_00650	COG3108	Peptidase M15
PE794_00655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PE794_00670	COG0537	adenosine 5'-monophosphoramidase activity
PE794_00675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PE794_00680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PE794_00685	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PE794_00690	COG1162	GTPase activity
PE794_00695	COG0583	DNA-binding transcription factor activity
PE794_00700	COG1011	Hydrolase
PE794_00705	COG0583	DNA-binding transcription factor activity
PE794_00715	COG0252	asparaginase activity
PE794_00725	COG5413	integral membrane protein
PE794_00740	COG3835	regulator
PE794_00745	COG2610	gluconate transmembrane transporter activity
PE794_00750	COG1929	Belongs to the glycerate kinase type-1 family
PE794_00755	COG1254	Belongs to the acylphosphatase family
PE794_00760	COG3593	DNA synthesis involved in DNA repair
PE794_00765	COG1611	Belongs to the LOG family
PE794_00770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PE794_00780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PE794_00785	COG0316	Belongs to the HesB IscA family
PE794_00785	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PE794_00790	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PE794_00795	COG1805	sodium ion transport
PE794_00800	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PE794_00805	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PE794_00810	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PE794_00815	COG2871	sodium ion transport
PE794_00820	COG1477	protein flavinylation
PE794_00825	COG2991	Protein conserved in bacteria
PE794_00835	COG2814	Major facilitator Superfamily
PE794_00840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PE794_00850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PE794_00865	COG4657	Part of a membrane complex involved in electron transport
PE794_00870	COG2878	Part of a membrane complex involved in electron transport
PE794_00875	COG4656	Part of a membrane complex involved in electron transport
PE794_00885	COG4658	electron transport chain
PE794_00900	COG1560	Kdo2-lipid A biosynthetic process
PE794_00905	COG0402	S-adenosylhomocysteine deaminase activity
PE794_00910	COG4143	(ABC) transporter
PE794_00915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PE794_00920	COG0617	tRNA 3'-terminal CCA addition
PE794_00925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PE794_00935	COG2911	Protein conserved in bacteria
PE794_00945	COG0346	lactoylglutathione lyase activity
PE794_00950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PE794_00960	COG1605	Chorismate mutase
PE794_00960	COG0287	Prephenate dehydrogenase
PE794_00965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PE794_00970	COG0859	PFAM glycosyl transferase family 9
PE794_00975	COG0469	pyruvate kinase activity
PE794_00980	COG2062	phosphohistidine phosphatase, SixA
PE794_00985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PE794_00990	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PE794_00995	COG0733	neurotransmitter:sodium symporter activity
PE794_01000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PE794_01005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PE794_01010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PE794_01015	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PE794_01020	COG4972	Pilus assembly protein
PE794_01040	COG4796	Type ii and iii secretion system protein
PE794_01045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PE794_01050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PE794_01055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PE794_01060	COG1280	lysine exporter protein (LysE YggA)
PE794_01065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PE794_01075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PE794_01090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PE794_01150	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PE794_01155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PE794_01160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PE794_01180	COG1253	flavin adenine dinucleotide binding
PE794_01185	COG0564	pseudouridine synthase activity
PE794_01190	COG0588	phosphoglycerate mutase activity
PE794_01195	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PE794_01200	COG1678	Uncharacterized ACR, COG1678
PE794_01205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PE794_01215	COG0271	Belongs to the BolA IbaG family
PE794_01240	COG0653	protein targeting
PE794_01250	COG0494	nUDIX hydrolase
PE794_01255	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PE794_01265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PE794_01275	COG1629	transport
PE794_01275	COG4771	TonB-dependent receptor
PE794_01280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PE794_01285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PE794_01290	COG0083	homoserine kinase activity
PE794_01295	COG0460	homoserine dehydrogenase
PE794_01295	COG0527	aspartate kinase activity
PE794_01300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PE794_01305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PE794_01310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PE794_01340	COG2195	Cleaves the N-terminal amino acid of tripeptides
PE794_01345	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PE794_01350	COG0194	GDP metabolic process
PE794_01355	COG1538	Outer membrane efflux protein
PE794_01360	COG2914	Belongs to the UPF0125 (RnfH) family
PE794_01365	COG2867	negative regulation of translational initiation
PE794_01370	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PE794_01375	COG4149	molybdate abc transporter
PE794_01380	COG0725	ABC transporter, periplasmic molybdate-binding protein
PE794_01385	COG0842	Transport permease protein
PE794_01390	COG1131	(ABC) transporter
PE794_01395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PE794_01400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PE794_01410	COG0251	oxidation-reduction process
PE794_01415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PE794_01420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PE794_01425	COG1121	(ABC) transporter
PE794_01435	COG2920	part of a sulfur-relay system
PE794_01440	COG0670	Belongs to the BI1 family
PE794_01445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PE794_01455	COG0322	excinuclease ABC activity
PE794_01460	COG0084	hydrolase, TatD family'
PE794_01465	COG0210	DNA helicase
PE794_01470	COG3842	ATPase activity
PE794_01475	COG1176	ABC-type spermidine putrescine transport system, permease component I
PE794_01480	COG1177	transmembrane transport
PE794_01490	COG2255	four-way junction helicase activity
PE794_01500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PE794_01535	COG0488	(ABC) transporter
PE794_01540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PE794_01550	COG1271	oxidase subunit
PE794_01555	COG1294	oxidase, subunit
PE794_01570	COG0824	Thioesterase
PE794_01575	COG0811	peptide transport
PE794_01580	COG0848	biopolymer transport protein
PE794_01585	COG3064	Membrane
PE794_01585	COG3064	Membrane
PE794_01590	COG0823	Involved in the tonB-independent uptake of proteins
PE794_01605	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PE794_01610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PE794_01620	COG0488	(ABC) transporter
PE794_01635	COG0303	'Molybdopterin
PE794_01640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PE794_01650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PE794_01655	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PE794_01665	COG0564	pseudouridine synthase activity
PE794_01670	COG3023	N-Acetylmuramoyl-L-alanine amidase
PE794_01675	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PE794_01680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PE794_01685	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PE794_01690	COG0626	cystathionine gamma-synthase activity
PE794_01695	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PE794_01710	COG1702	phosphate starvation-inducible protein PhoH
PE794_01775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PE794_01795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PE794_01805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PE794_01810	COG1137	ATPase activity
PE794_01815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PE794_01825	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PE794_01830	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PE794_01840	COG1704	LemA family
PE794_01850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PE794_01850	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PE794_01850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PE794_01855	COG1105	Belongs to the carbohydrate kinase PfkB family
PE794_01860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PE794_01860	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PE794_01870	COG1523	belongs to the glycosyl hydrolase 13 family
PE794_01875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PE794_01880	COG0297	glycogen (starch) synthase activity
PE794_01885	COG0058	SHG alpha-glucan phosphorylase activity
PE794_01900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PE794_01900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PE794_01915	COG1187	pseudouridine synthase activity
PE794_01920	COG2814	Major facilitator Superfamily
PE794_01930	COG3381	protein complex oligomerization
PE794_01940	COG0791	NLP P60 protein
PE794_01945	COG2932	Transcriptional regulator
PE794_01950	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
PE794_01955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PE794_01960	COG2990	Protein conserved in bacteria
PE794_01970	COG1643	Atp-dependent helicase
PE794_01975	COG2707	UPF0756 membrane protein
PE794_01985	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PE794_01990	COG0534	Mate efflux family protein
PE794_01995	COG1074	ATP-dependent DNA helicase activity
PE794_02000	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PE794_02005	COG4535	Mg2 and Co2 transporter CorC
PE794_02015	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PE794_02020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PE794_02025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PE794_02030	COG2271	Major facilitator Superfamily
PE794_02035	COG0584	glycerophosphoryl diester phosphodiesterase
PE794_02040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PE794_02045	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
PE794_02050	COG0247	lactate metabolic process
PE794_02080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PE794_02080	COG0517	IMP dehydrogenase activity
PE794_02090	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
PE794_02095	COG0385	Bile acid
PE794_02100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE794_02105	COG0561	phosphatase activity
PE794_02115	COG1595	DNA-templated transcription, initiation
PE794_02120	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
PE794_02130	COG0318	PFAM AMP-dependent synthetase and ligase
PE794_02135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PE794_02140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PE794_02145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PE794_02150	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PE794_02170	COG1160	GTP binding
PE794_02180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PE794_02195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PE794_02200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PE794_02215	COG0750	zinc metalloprotease
PE794_02220	COG0575	Belongs to the CDS family
PE794_02225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PE794_02230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PE794_02240	COG0671	phosphoesterase, PA-phosphatase related
PE794_02245	COG1534	Rna-binding protein
PE794_02250	COG0463	Glycosyl transferase, family 2
PE794_02255	COG1686	Belongs to the peptidase S11 family
PE794_02260	COG0859	PFAM glycosyl transferase family 9
PE794_02270	COG0328	RNA-DNA hybrid ribonuclease activity
PE794_02275	COG1286	toxin biosynthetic process
PE794_02280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PE794_02290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PE794_02295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PE794_02305	COG0251	oxidation-reduction process
PE794_02310	COG1496	oxidoreductase activity
PE794_02320	COG5645	(Lipo)protein
PE794_02335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PE794_02345	COG1792	Involved in formation and maintenance of cell shape
PE794_02350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PE794_02355	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PE794_02360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PE794_02365	COG0121	glutamine amidotransferase
PE794_02370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PE794_02375	COG2949	membrane
PE794_02395	COG1556	Lactate utilization protein
PE794_02400	COG1139	Iron-sulfur cluster binding protein
PE794_02405	COG0247	lactate metabolic process
PE794_02410	COG1620	l-lactate permease
PE794_02415	COG2916	Histone family protein nucleoid-structuring protein H-NS
PE794_02420	COG1757	Na H antiporter
PE794_02425	COG1879	ABC-type sugar transport system periplasmic component
PE794_02430	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PE794_02440	COG2990	Protein conserved in bacteria
PE794_02445	COG0508	dehydrogenase complex catalyzes the overall conversion of
PE794_02450	COG0567	Dehydrogenase, E1 component
PE794_02455	COG1121	(ABC) transporter
PE794_02460	COG0739	heme binding
PE794_02465	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PE794_02470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PE794_02480	COG0561	phosphatase activity
PE794_02485	COG3850	Histidine kinase
PE794_02495	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PE794_02505	COG2759	Belongs to the formate--tetrahydrofolate ligase family
PE794_02515	COG4221	oxidoreductase activity
PE794_02520	COG0133	tryptophan synthase activity
PE794_02540	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PE794_02540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PE794_02545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PE794_02555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PE794_02560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PE794_02590	COG0640	Transcriptional regulator
PE794_02600	COG0189	ligase activity
PE794_02605	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PE794_02610	COG0280	phosphate acetyltransferase
PE794_02610	COG0281	malic enzyme
PE794_02615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PE794_02715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PE794_02720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PE794_02750	COG1403	HNH endonuclease
PE794_02825	COG0740	serine-type endopeptidase activity
PE794_02905	COG3683	transport system, periplasmic component
PE794_02910	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
PE794_02915	COG1115	amino acid carrier protein
PE794_02920	COG1116	anion transmembrane transporter activity
PE794_02925	COG1116	anion transmembrane transporter activity
PE794_02930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PE794_02935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PE794_02940	COG2022	thiamine diphosphate biosynthetic process
PE794_02945	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PE794_02950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PE794_02955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PE794_02970	COG0481	GTPase activity
PE794_02975	COG0681	Belongs to the peptidase S26 family
PE794_02980	COG0571	ribonuclease III activity
PE794_02985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PE794_02990	COG1381	Involved in DNA repair and RecF pathway recombination
PE794_03075	COG0433	COG0433 Predicted ATPase
PE794_03080	COG1840	ABC-type Fe3 transport system, periplasmic component
PE794_03100	COG4178	(ABC) transporter
PE794_03115	COG2194	sulfuric ester hydrolase activity
PE794_03120	COG0528	UMP kinase activity
PE794_03125	COG0233	cytoplasmic translational termination
PE794_03130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PE794_03145	COG0590	tRNA wobble adenosine to inosine editing
PE794_03150	COG0513	Belongs to the DEAD box helicase family
PE794_03155	COG4785	May be involved in cell division
PE794_03160	COG1185	polyribonucleotide nucleotidyltransferase activity
PE794_03165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PE794_03175	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
PE794_03190	COG3083	sulfuric ester hydrolase activity
PE794_03195	COG3082	Protein of unknown function (DUF1414)
PE794_03200	COG1309	transcriptional regulator
PE794_03205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE794_03210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PE794_03225	COG3955	Domain of unknown function (DUF1919)
PE794_03230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PE794_03245	COG0517	IMP dehydrogenase activity
PE794_03245	COG0516	GMP reductase activity
PE794_03250	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PE794_03255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PE794_03260	COG0814	amino acid
PE794_03265	COG0814	amino acid
PE794_03275	COG3105	Protein conserved in bacteria
PE794_03280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PE794_03290	COG3022	response to hydroperoxide
PE794_03305	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
PE794_03310	COG1823	symporter activity
PE794_03315	COG0778	Nitroreductase
PE794_03320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PE794_03325	COG0072	phenylalanine-tRNA ligase activity
PE794_03330	COG0776	regulation of translation
PE794_03335	COG0791	NLP P60 protein
PE794_03345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PE794_03350	COG1846	Transcriptional regulator
PE794_03350	COG1940	carbohydrate kinase activity
PE794_03355	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PE794_03360	COG1522	sequence-specific DNA binding
PE794_03365	COG1674	ftsk spoiiie
PE794_03370	COG2321	neutral zinc metallopeptidase
PE794_03375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PE794_03380	COG1214	PFAM Peptidase M22, glycoprotease
PE794_03385	COG1435	thymidine kinase activity
PE794_03390	COG3074	FtsZ-dependent cytokinesis
PE794_03395	COG1494	fructose-1,6-bisphosphatase
PE794_03400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PE794_03405	COG0577	efflux transmembrane transporter activity
PE794_03405	COG1136	(ABC) transporter
PE794_03410	COG2205	protein histidine kinase activity
PE794_03415	COG0745	RESPONSE REGULATOR receiver
PE794_03420	COG3956	TIGRFAM MazG family protein
PE794_03430	COG0285	dihydrofolate synthase activity
PE794_03440	COG0779	Required for maturation of 30S ribosomal subunits
PE794_03445	COG0195	Participates in both transcription termination and antitermination
PE794_03450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PE794_03455	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PE794_03460	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PE794_03465	COG2951	lytic endotransglycosylase activity
PE794_03475	COG0280	phosphate acetyltransferase
PE794_03475	COG0857	belongs to the CobB CobQ family
PE794_03485	COG0737	Belongs to the 5'-nucleotidase family
PE794_03505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PE794_03515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PE794_03525	COG0589	response to stress
PE794_03535	COG2969	positive regulation of protein catabolic process
PE794_03540	COG0625	glutathione transferase activity
PE794_03545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PE794_03555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PE794_03560	COG1448	Aminotransferase
PE794_03565	COG0006	proline dipeptidase activity
PE794_03575	COG0556	nucleotide-excision repair
PE794_03580	COG2822	iron ion transport
PE794_03585	COG2837	iron assimilation
PE794_03595	COG0613	PHP domain protein
PE794_03605	COG2925	Exonuclease
PE794_03610	COG0038	chloride channel
PE794_03615	COG0017	Asparaginyl-tRNA synthetase
PE794_03620	COG1509	lysine 2,3-aminomutase activity
PE794_03630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PE794_03635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PE794_03645	COG0741	lytic transglycosylase activity
PE794_03650	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PE794_03655	COG0626	cystathionine gamma-synthase activity
PE794_03660	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PE794_03665	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PE794_03670	COG2363	Small membrane protein
PE794_03675	COG0277	FAD linked oxidase domain protein
PE794_03680	COG0243	molybdopterin cofactor binding
PE794_03685	COG3005	denitrification pathway
PE794_03695	COG0315	cyclic pyranopterin monophosphate synthase activity
PE794_03700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PE794_03705	COG0314	molybdopterin synthase activity
PE794_03710	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PE794_03715	COG1444	tRNA N-acetyltransferase activity
PE794_03725	COG0583	DNA-binding transcription factor activity
PE794_03735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PE794_03750	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PE794_03755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PE794_03770	COG1737	Transcriptional regulator
PE794_03775	COG2731	YhcH YjgK YiaL family protein
PE794_03780	COG0248	Ppx GppA phosphatase
PE794_03790	COG0527	aspartate kinase activity
PE794_03795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PE794_03800	COG3100	YcgL domain-containing protein
PE794_03805	COG0305	Participates in initiation and elongation during chromosome replication
PE794_03810	COG4607	ABC-type enterochelin transport system periplasmic component
PE794_03815	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PE794_03820	COG4605	iron ion homeostasis
PE794_03825	COG4604	ABC transporter, ATP-binding protein
PE794_03830	COG1392	Phosphate transport regulator
PE794_03835	COG0306	phosphate transporter
PE794_03840	COG4991	sh3 domain protein
PE794_03850	COG3945	hemerythrin HHE cation binding domain
PE794_03855	COG0343	queuine tRNA-ribosyltransferase activity
PE794_03870	COG1278	Cold shock
PE794_03875	COG0288	reversible hydration of carbon dioxide
PE794_03880	COG0028	Belongs to the TPP enzyme family
PE794_03885	COG0440	acetolactate synthase activity
PE794_03890	COG0312	modulator of DNA gyrase
PE794_03895	COG3028	Belongs to the UPF0307 family
PE794_03900	COG3094	Invasion gene expression up-regulator, SirB
PE794_03910	COG1811	Na channel or pump
PE794_03915	COG3787	Belongs to the UPF0306 family
PE794_03920	COG0023	Translation Initiation Factor
PE794_03925	COG0284	orotidine-5'-phosphate decarboxylase activity
PE794_03930	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PE794_03935	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
PE794_03940	COG0776	regulation of translation
PE794_03945	COG0539	negative regulation of cytoplasmic translation
PE794_03955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PE794_03965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PE794_03975	COG1785	Belongs to the alkaline phosphatase family
PE794_03980	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
PE794_03990	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PE794_03990	COG3264	Mechanosensitive ion channel
PE794_03995	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PE794_03995	COG3264	Mechanosensitive ion channel
PE794_04000	COG0318	PFAM AMP-dependent synthetase and ligase
PE794_04005	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PE794_04010	COG0596	Alpha beta hydrolase
PE794_04015	COG2226	methyltransferase
PE794_04020	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PE794_04035	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
PE794_04040	COG1380	Effector of murein hydrolase LrgA
PE794_04045	COG1346	cytolysis
PE794_04050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PE794_04060	COG3036	rescue of stalled ribosome
PE794_04065	COG2226	methyltransferase
PE794_04085	COG2333	competence protein COMEC
PE794_04085	COG0658	competence protein
PE794_04090	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PE794_04095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PE794_04100	COG0737	Belongs to the 5'-nucleotidase family
PE794_04125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PE794_04130	COG0508	dehydrogenase complex catalyzes the overall conversion of
PE794_04135	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PE794_04140	COG0167	dihydroorotate dehydrogenase activity
PE794_04145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PE794_04160	COG1132	(ABC) transporter
PE794_04165	COG1346	cytolysis
PE794_04175	COG1199	ATP-dependent helicase activity
PE794_04185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PE794_04190	COG0629	single-stranded DNA binding
PE794_04220	COG2070	2-Nitropropane dioxygenase
PE794_04230	COG2814	Major facilitator Superfamily
PE794_04235	COG2315	Protein conserved in bacteria
PE794_04240	COG4172	Belongs to the ABC transporter superfamily
PE794_04245	COG4171	peptide transport system, permease
PE794_04250	COG4168	peptide transport system, permease
PE794_04255	COG4166	transmembrane transport
PE794_04260	COG3283	Transcriptional regulator of aromatic amino acids metabolism
PE794_04265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PE794_04270	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PE794_04275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PE794_04295	COG1368	sulfuric ester hydrolase activity
PE794_04300	COG3217	Mosc domain protein beta barrel domain protein
PE794_04300	COG0633	Ferredoxin
PE794_04305	COG1722	exodeoxyribonuclease VII activity
PE794_04310	COG0142	geranyltranstransferase activity
PE794_04320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PE794_04325	COG1530	ribonuclease E activity
PE794_04330	COG1944	ATP diphosphatase activity
PE794_04345	COG0500	methyltransferase
PE794_04355	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PE794_04375	COG2351	hydroxyisourate hydrolase activity
PE794_04385	COG0586	Pfam SNARE associated Golgi protein
PE794_04390	COG0187	DNA topoisomerase II activity
PE794_04400	COG1349	DNA-binding transcription factor activity
PE794_04405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PE794_04410	COG2915	High frequency lysogenization protein hflD homolog
PE794_04415	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PE794_04420	COG4988	ABC transporter
PE794_04425	COG2911	Protein conserved in bacteria
PE794_04430	COG0729	surface antigen
PE794_04435	COG2861	carbohydrate metabolic process
PE794_04440	COG4942	peptidase
PE794_04445	COG0588	phosphoglycerate mutase activity
PE794_04455	COG0572	uridine kinase
PE794_04460	COG0717	Belongs to the dCTP deaminase family
PE794_04465	COG1309	transcriptional regulator
PE794_04470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE794_04475	COG0842	Transport permease protein
PE794_04475	COG1129	ABC transporter
PE794_04480	COG0842	Transport permease protein
PE794_04490	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PE794_04495	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PE794_04500	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PE794_04510	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PE794_04515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PE794_04520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PE794_04525	COG4166	transmembrane transport
PE794_04535	COG0444	Belongs to the ABC transporter superfamily
PE794_04540	COG4608	Belongs to the ABC transporter superfamily
PE794_04550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PE794_04560	COG0747	negative chemotaxis
PE794_04570	COG0814	amino acid
PE794_04575	COG1760	l-serine dehydratase
PE794_04585	COG0135	phosphoribosylanthranilate isomerase activity
PE794_04585	COG0134	indole-3-glycerol-phosphate synthase activity
PE794_04590	COG3177	Filamentation induced by cAMP protein fic
PE794_04595	COG3098	single-species biofilm formation
PE794_04600	COG0564	pseudouridine synthase activity
PE794_04605	COG3140	Belongs to the UPF0181 family
PE794_04615	COG3025	triphosphatase activity
PE794_04620	COG3106	COG3106 Predicted ATPase
PE794_04625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PE794_04635	COG1473	amidohydrolase
PE794_04640	COG3069	C4-dicarboxylate transmembrane transporter activity
PE794_04650	COG0495	leucyl-tRNA aminoacylation
PE794_04655	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
PE794_04660	COG1466	dna polymerase III delta subunit
PE794_04665	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PE794_04670	COG0237	dephospho-CoA kinase activity
PE794_04680	COG1459	type II secretion system
PE794_04685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PE794_04690	COG4969	Belongs to the N-Me-Phe pilin family
PE794_04695	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PE794_04705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PE794_04710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PE794_04715	COG0730	response to heat
PE794_04720	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PE794_04730	COG1024	Enoyl-CoA hydratase
PE794_04730	COG1250	3-hydroxyacyl-CoA dehydrogenase
PE794_04745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PE794_04755	COG0437	4 iron, 4 sulfur cluster binding
PE794_04760	COG2864	formate dehydrogenase
PE794_04765	COG3058	Necessary for formate dehydrogenase activity
PE794_04795	COG1560	Kdo2-lipid A biosynthetic process
PE794_04800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PE794_04810	COG0302	gtp cyclohydrolase
PE794_04815	COG3642	lipopolysaccharide core region biosynthetic process
PE794_04825	COG0110	maltose O-acetyltransferase activity
PE794_04840	COG4382	Mu-like prophage protein Gp16
PE794_04865	COG4396	Host-nuclease inhibitor protein Gam
PE794_04875	COG3267	Type II secretory pathway component ExeA
PE794_04875	COG3409	Peptidoglycan-binding domain 1 protein
PE794_04965	COG4373	Mu-like prophage FluMu protein gp28
PE794_05070	COG3392	D12 class N6 adenine-specific DNA methyltransferase
PE794_05080	COG0583	DNA-binding transcription factor activity
PE794_05100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PE794_05110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PE794_05115	COG0617	tRNA 3'-terminal CCA addition
PE794_05140	COG2975	iron-sulfur cluster assembly
PE794_05145	COG0633	Ferredoxin
PE794_05165	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PE794_05175	COG0822	iron-sulfur transferase activity
PE794_05180	COG1104	cysteine desulfurase activity
PE794_05185	COG1959	2 iron, 2 sulfur cluster binding
PE794_05195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PE794_05200	COG0784	Response regulator, receiver
PE794_05200	COG5002	protein histidine kinase activity
PE794_05200	COG2198	Histidine kinase
PE794_05205	COG0697	spore germination
PE794_05210	COG2840	Smr protein MutS2
PE794_05215	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PE794_05220	COG2226	methyltransferase
PE794_05225	COG2830	Protein of unknown function (DUF452)
PE794_05230	COG0156	8-amino-7-oxononanoate synthase activity
PE794_05235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PE794_05245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PE794_05250	COG2027	D-alanyl-D-alanine carboxypeptidase
PE794_05285	COG1444	tRNA N-acetyltransferase activity
PE794_05290	COG0138	bifunctional purine biosynthesis protein purh
PE794_05300	COG3210	domain, Protein
PE794_05320	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PE794_05325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PE794_05340	COG2985	domain, Protein
PE794_05340	COG0569	domain protein
PE794_05345	COG0786	glutamate:sodium symporter activity
PE794_05360	COG2350	Protein conserved in bacteria
PE794_05365	COG1607	acyl-coa hydrolase
PE794_05380	COG3092	negative regulation of chromosome organization
PE794_05390	COG2056	Na+-H+ antiporter family
PE794_05395	COG0708	Exodeoxyribonuclease III
PE794_05400	COG0583	DNA-binding transcription factor activity
PE794_05410	COG3306	glycosyltransferase involved in LPS biosynthesis
PE794_05425	COG0254	rRNA binding
PE794_05440	COG0753	catalase activity
PE794_05445	COG2963	transposase activity
PE794_05455	COG1408	metallophosphoesterase
PE794_05460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PE794_05465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PE794_05470	COG1085	galactose-1-phosphate uridylyltransferase
PE794_05480	COG2017	converts alpha-aldose to the beta-anomer
PE794_05500	COG0489	protein tyrosine kinase activity
PE794_05510	COG2095	MarC family integral membrane protein
PE794_05515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PE794_05525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PE794_05530	COG2354	Protein conserved in bacteria
PE794_05535	COG3071	HemY protein
PE794_05540	COG2959	enzyme of heme biosynthesis
PE794_05550	COG0181	hydroxymethylbilane synthase activity
PE794_05555	COG1454	alcohol dehydrogenase
PE794_05555	COG1012	belongs to the aldehyde dehydrogenase family
PE794_05570	COG0813	purine-nucleoside phosphorylase activity
PE794_05575	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PE794_05580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PE794_05585	COG2364	Membrane
PE794_05590	COG0800	Aldolase
PE794_05595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PE794_05600	COG1904	glucuronate isomerase
PE794_05610	COG2186	Transcriptional regulator
PE794_05620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PE794_05620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PE794_05625	COG1216	Glycosyl transferase, family 2
PE794_05630	COG1216	Glycosyl transferase, family 2
PE794_05640	COG3306	glycosyltransferase involved in LPS biosynthesis
PE794_05650	COG5039	Polysaccharide pyruvyl transferase
PE794_05655	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PE794_05660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PE794_05665	COG1605	Chorismate mutase
PE794_05665	COG0077	Prephenate dehydratase
PE794_05670	COG0339	signal peptide processing
PE794_05675	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PE794_05680	COG1882	Formate acetyltransferase
PE794_05685	COG2116	formate transmembrane transporter activity
PE794_05690	COG1238	metal cluster binding
PE794_05695	COG0501	Belongs to the peptidase M48B family
PE794_05705	COG2431	L-lysine efflux transmembrane transporter activity
PE794_05710	COG1169	isochorismate synthase
PE794_05715	COG0436	Aminotransferase
PE794_05725	COG2962	Rard protein
PE794_05730	COG1280	lysine exporter protein (LysE YggA)
PE794_05735	COG1629	transport
PE794_05735	COG4771	TonB-dependent receptor
PE794_05740	COG0748	coenzyme F420 binding
PE794_05750	COG4235	cytochrome complex assembly
PE794_05750	COG3088	subunit of a heme lyase
PE794_05755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PE794_05760	COG1138	Cytochrome C-type biogenesis protein
PE794_05765	COG0475	glutathione-regulated potassium exporter activity
PE794_05765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PE794_05775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PE794_05790	COG3111	PFAM Bacterial OB fold (BOF) protein
PE794_05805	COG0745	RESPONSE REGULATOR receiver
PE794_05810	COG0642	Histidine kinase
PE794_05815	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
PE794_05820	COG1862	Preprotein translocase
PE794_05825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PE794_05830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PE794_05835	COG1528	Iron-storage protein
PE794_05840	COG1528	Iron-storage protein
PE794_05845	COG2252	PERMEase
PE794_05850	COG0424	maF-like protein
PE794_05865	COG0583	DNA-binding transcription factor activity
PE794_05885	COG1373	ATPase (AAA superfamily
PE794_05900	COG1902	pentaerythritol trinitrate reductase activity
PE794_05905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PE794_05905	COG0301	tRNA thio-modification
PE794_05910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PE794_05915	COG0330	HflC and HflK could
PE794_05920	COG0330	HflC and HflK could
PE794_05925	COG3118	belongs to the thioredoxin family
PE794_05945	COG0531	amino acid
PE794_05950	COG0531	amino acid
PE794_05965	COG3047	cAMP biosynthetic process
PE794_05970	COG0542	response to heat
PE794_05975	COG0798	PFAM Bile acid sodium symporter
PE794_05980	COG1393	Belongs to the ArsC family
PE794_05990	COG1027	Aspartate ammonia-lyase
PE794_06000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PE794_06005	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PE794_06005	COG3064	Membrane
PE794_06005	COG3583	domain protein
PE794_06015	COG0720	synthase
PE794_06020	COG0602	queuosine metabolic process
PE794_06045	COG0795	lipopolysaccharide-transporting ATPase activity
PE794_06050	COG0795	lipopolysaccharide-transporting ATPase activity
PE794_06060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PE794_06065	COG2937	Belongs to the GPAT DAPAT family
PE794_06070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PE794_06075	COG3066	DNA modification
PE794_06080	COG0861	Integral membrane protein TerC family
PE794_06085	COG1472	Belongs to the glycosyl hydrolase 3 family
PE794_06090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PE794_06095	COG0148	phosphopyruvate hydratase activity
PE794_06100	COG1051	belongs to the nudix hydrolase family
PE794_06105	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
PE794_06115	COG1965	Belongs to the frataxin family
PE794_06125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PE794_06130	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PE794_06135	COG0564	pseudouridine synthase activity
PE794_06145	COG0205	6-phosphofructokinase activity
PE794_06150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PE794_06155	COG1525	nuclease
PE794_06160	COG1115	amino acid carrier protein
PE794_06165	COG0628	permease
PE794_06175	COG0826	peptidase U32
PE794_06180	COG3307	-O-antigen
PE794_06185	COG1519	Transferase
PE794_06195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PE794_06200	COG0802	atpase or kinase
PE794_06205	COG0860	N-Acetylmuramoyl-L-alanine amidase
PE794_06205	COG1388	LysM domain
PE794_06210	COG0166	Belongs to the GPI family
PE794_06215	COG2960	long-chain fatty acid transporting porin activity
PE794_06235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PE794_06245	COG0551	DNA topoisomerase type I activity
PE794_06255	COG2137	regulation of response to DNA damage stimulus
PE794_06260	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PE794_06265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PE794_06275	COG1322	Protein conserved in bacteria
PE794_06280	COG0512	Glutamine amidotransferase of anthranilate synthase
PE794_06290	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PE794_06295	COG0494	nUDIX hydrolase
PE794_06310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PE794_06315	COG0612	Peptidase, M16
PE794_06325	COG0471	metal ion transport
PE794_06330	COG0583	DNA-binding transcription factor activity
PE794_06335	COG3266	domain, Protein
PE794_06340	COG1187	pseudouridine synthase activity
PE794_06345	COG0009	L-threonylcarbamoyladenylate synthase
PE794_06355	COG2837	iron assimilation
PE794_06360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PE794_06365	COG0512	Glutamine amidotransferase of anthranilate synthase
PE794_06375	COG2226	methyltransferase
PE794_06380	COG2268	Band 7 protein
PE794_06385	COG2841	Protein conserved in bacteria
PE794_06400	COG2965	DNA replication, synthesis of RNA primer
PE794_06415	COG3201	nicotinamide mononucleotide transporter
PE794_06420	COG2976	Protein conserved in bacteria
PE794_06430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PE794_06435	COG1426	Protein conserved in bacteria
PE794_06440	COG0659	secondary active sulfate transmembrane transporter activity
PE794_06450	COG0673	inositol 2-dehydrogenase activity
PE794_06455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PE794_06455	COG0475	glutathione-regulated potassium exporter activity
PE794_06500	COG1764	response to oxidative stress
PE794_06530	COG2207	Transcriptional regulator
PE794_06540	COG1902	pentaerythritol trinitrate reductase activity
PE794_06545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PE794_06550	COG2084	Dehydrogenase
PE794_06555	COG0778	Nitroreductase
PE794_06560	COG2095	MarC family integral membrane protein
PE794_06575	COG0625	glutathione transferase activity
PE794_06590	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PE794_06595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PE794_06610	COG1275	C4-dicarboxylate transporter malic acid transport protein
PE794_06615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PE794_06630	COG1132	(ABC) transporter
PE794_06635	COG1854	S-ribosylhomocysteine lyase activity
PE794_06640	COG3008	intermembrane lipid transfer
PE794_06645	COG0735	belongs to the Fur family
PE794_06650	COG0716	FMN binding
PE794_06660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PE794_06665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PE794_06670	COG2252	PERMEase
PE794_06675	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PE794_06680	COG2081	HI0933 family
PE794_06685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PE794_06695	COG0560	Phosphoserine phosphatase
PE794_06710	COG0058	SHG alpha-glucan phosphorylase activity
PE794_06715	COG2909	trisaccharide binding
PE794_06725	COG4580	involved in the transport of maltose and maltodextrins
PE794_06730	COG3842	ATPase activity
PE794_06745	COG3833	ABC-type maltose transport systems, permease component
PE794_06750	COG1640	4-alpha-glucanotransferase
PE794_06755	COG1966	Carbon starvation protein
PE794_06760	COG0084	hydrolase, TatD family'
PE794_06765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PE794_06775	COG0778	Nitroreductase
PE794_06790	COG4172	Belongs to the ABC transporter superfamily
PE794_06795	COG0191	fructose-bisphosphate aldolase activity
PE794_06800	COG0126	phosphoglycerate kinase activity
PE794_06805	COG0471	metal ion transport
PE794_06810	COG0471	metal ion transport
PE794_06815	COG0471	metal ion transport
PE794_06820	COG0187	DNA topoisomerase II activity
PE794_06825	COG5002	protein histidine kinase activity
PE794_06830	COG0745	RESPONSE REGULATOR receiver
PE794_06855	COG0789	Transcriptional regulator
PE794_06875	COG0300	oxidoreductase activity
PE794_06880	COG0778	Nitroreductase
PE794_06885	COG0616	signal peptide processing
PE794_06890	COG3719	Belongs to the RNase T2 family
PE794_06900	COG1252	NADH dehydrogenase
PE794_06905	COG2183	response to ionizing radiation
PE794_06910	COG3063	Type IV pilus biogenesis stability protein PilW
PE794_06915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PE794_06950	COG2161	toxin-antitoxin pair type II binding
PE794_06955	COG4115	mRNA cleavage
PE794_06960	COG2835	tetraacyldisaccharide 4'-kinase activity
PE794_06970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PE794_06975	COG0740	serine-type endopeptidase activity
PE794_06980	COG2166	iron-sulfur cluster assembly
PE794_07000	COG0488	(ABC) transporter
PE794_07005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PE794_07020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PE794_07025	COG5007	Belongs to the BolA IbaG family
PE794_07035	COG2854	intermembrane phospholipid transfer
PE794_07040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PE794_07045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PE794_07050	COG1127	ABC transporter
PE794_07055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PE794_07060	COG1090	epimerase
PE794_07080	COG0563	adenylate kinase activity
PE794_07090	COG2814	Major facilitator Superfamily
PE794_07120	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PE794_07140	COG2814	Major facilitator Superfamily
PE794_07145	COG0363	glucosamine-6-phosphate deaminase activity
PE794_07150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PE794_07155	COG1218	3'(2'),5'-bisphosphate nucleotidase
PE794_07160	COG0494	nUDIX hydrolase
PE794_07165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PE794_07175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PE794_07180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PE794_07195	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PE794_07200	COG1178	ABC-type Fe3 transport system permease component
PE794_07205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PE794_07210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PE794_07215	COG2190	(PTS) system
PE794_07225	COG0210	DNA helicase
PE794_07230	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PE794_07235	COG0409	Hydrogenase expression formation protein
PE794_07240	COG0309	Hydrogenase expression formation protein (HypE)
PE794_07245	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PE794_07250	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
PE794_07255	COG0437	4 iron, 4 sulfur cluster binding
PE794_07260	COG5557	Pfam Polysulphide reductase, NrfD
PE794_07265	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
PE794_07270	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PE794_07275	COG1773	rubredoxin
PE794_07280	COG0298	carbon dioxide binding
PE794_07285	COG0375	protein maturation
PE794_07320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PE794_07325	COG0308	aminopeptidase N
PE794_07330	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PE794_07335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PE794_07340	COG0295	cytidine deaminase activity
PE794_07345	COG2177	Part of the ABC transporter FtsEX involved in
PE794_07350	COG2884	Cell division ATP-binding protein ftsE
PE794_07355	COG0552	protein localization to endoplasmic reticulum
PE794_07360	COG0742	ribosomal rna small subunit methyltransferase
PE794_07365	COG3099	Belongs to the UPF0263 family
PE794_07370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PE794_07380	COG4160	amino acid transport
PE794_07385	COG4215	(ABC) transporter
PE794_07390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE794_07395	COG1126	abc transporter atp-binding protein
PE794_07400	COG1881	PFAM PEBP family protein
PE794_07410	COG3620	sequence-specific DNA binding
PE794_07420	COG4232	protein-disulfide reductase activity
PE794_07425	COG3101	peptidyl-lysine hydroxylation
PE794_07435	COG3107	peptidoglycan biosynthetic process
PE794_07440	COG0792	nuclease activity
PE794_07445	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PE794_07480	COG1138	Cytochrome C-type biogenesis protein
PE794_07490	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PE794_07495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PE794_07500	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PE794_07505	COG4133	protoheme IX ABC transporter activity
PE794_07510	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PE794_07545	COG3630	sodium ion export across plasma membrane
PE794_07555	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
PE794_07560	COG2824	Alkylphosphonate utilization operon protein PhnA
PE794_07565	COG1858	cytochrome C peroxidase
PE794_07570	COG1872	DUF167
PE794_07575	COG0762	integral membrane protein
PE794_07580	COG3171	Protein conserved in bacteria
PE794_07585	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PE794_07590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PE794_07595	COG0416	fatty acid biosynthetic process
PE794_07600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PE794_07605	COG1399	metal-binding, possibly nucleic acid-binding protein
PE794_07610	COG4137	Cytochrome C assembly protein
PE794_07615	COG4536	flavin adenine dinucleotide binding
PE794_07620	COG0733	neurotransmitter:sodium symporter activity
PE794_07630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PE794_07630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PE794_07635	COG3715	PTS system
PE794_07640	COG3716	PTS system mannose fructose sorbose family IID component
PE794_07680	COG1840	ABC-type Fe3 transport system, periplasmic component
PE794_07695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PE794_07710	COG0678	peroxiredoxin activity
PE794_07710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PE794_07715	COG0583	DNA-binding transcription factor activity
PE794_07720	COG1309	transcriptional regulator
PE794_07725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PE794_07730	COG0557	exoribonuclease II activity
PE794_07740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PE794_07745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PE794_07755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PE794_07760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PE794_07825	COG0316	Belongs to the HesB IscA family
PE794_07830	COG1575	Belongs to the MenA family. Type 1 subfamily
PE794_07835	COG1720	tRNA m6t6A37 methyltransferase activity
PE794_07845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PE794_07865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PE794_07870	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PE794_07875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PE794_07885	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PE794_07895	COG1755	Isoprenylcysteine carboxyl methyltransferase
PE794_07905	COG1530	ribonuclease E activity
PE794_07920	COG2249	NAD(P)H dehydrogenase (quinone) activity
PE794_07925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PE794_07935	COG0243	molybdopterin cofactor binding
PE794_07940	COG0437	4 iron, 4 sulfur cluster binding
PE794_07945	COG0348	domain, Protein
PE794_07950	COG3043	anaerobic respiration
PE794_07955	COG3005	denitrification pathway
PE794_07965	COG2050	protein possibly involved in aromatic compounds catabolism
PE794_07970	COG0247	lactate metabolic process
PE794_07970	COG0277	FAD linked oxidase domain protein
PE794_07975	COG2885	chlorophyll binding
PE794_07975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PE794_07980	COG1879	ABC-type sugar transport system periplasmic component
PE794_07985	COG1129	ABC transporter
PE794_07990	COG4211	Belongs to the binding-protein-dependent transport system permease family
PE794_08015	COG1022	Amp-dependent synthetase and ligase
PE794_08020	COG4989	oxidoreductase activity
PE794_08025	COG3691	Protein conserved in bacteria
PE794_08030	COG0814	amino acid
PE794_08050	COG4974	Belongs to the 'phage' integrase family
PE794_08055	COG0732	type I restriction modification DNA specificity domain
PE794_08080	COG1555	photosystem II stabilization
PE794_08085	COG3266	domain, Protein
PE794_08085	COG3061	Opacity-associated protein A
PE794_08095	COG0859	PFAM glycosyl transferase family 9
PE794_08100	COG0859	PFAM glycosyl transferase family 9
PE794_08105	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PE794_08110	COG0049	tRNA binding
PE794_08115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PE794_08120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PE794_08145	COG0825	malonyl-CoA metabolic process
PE794_08155	COG0204	Acyl-transferase
PE794_08160	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PE794_08185	COG0783	Belongs to the Dps family
PE794_08200	COG1289	transmembrane transporter activity
PE794_08205	COG1803	Methylglyoxal synthase
PE794_08210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PE794_08220	COG0525	valine-tRNA ligase activity
PE794_08235	COG2153	protein acetylation
PE794_08240	COG2927	DNA polymerase III (CHI subunit)
PE794_08245	COG1652	LysM domain
PE794_08255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PE794_08260	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PE794_08265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PE794_08270	COG1045	serine acetyltransferase
PE794_08275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PE794_08300	COG1072	(Pantothenic acid kinase))
PE794_08305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PE794_08320	COG0521	Mo-molybdopterin cofactor biosynthetic process
PE794_08330	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PE794_08335	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PE794_08340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PE794_08355	COG0625	glutathione transferase activity
PE794_08360	COG0019	diaminopimelate decarboxylase activity
PE794_08370	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PE794_08375	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
PE794_08380	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PE794_08385	COG1053	succinate dehydrogenase
PE794_08390	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PE794_08395	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PE794_08400	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PE794_08405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PE794_08415	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PE794_08420	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PE794_08425	COG2264	protein methyltransferase activity
PE794_08445	COG0037	tRNA processing
PE794_08455	COG4974	Belongs to the 'phage' integrase family
PE794_08515	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PE794_08530	COG1151	hydroxylamine reductase activity
PE794_08535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PE794_08540	COG2244	polysaccharide biosynthetic process
PE794_08545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PE794_08555	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PE794_08560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PE794_08565	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
PE794_08585	COG0728	peptidoglycan biosynthetic process
PE794_08590	COG0268	Binds directly to 16S ribosomal RNA
PE794_08595	COG0569	domain protein
PE794_08600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PE794_08605	COG3276	selenocysteine insertion sequence binding
PE794_08620	COG0716	FMN binding
PE794_08640	COG4771	TonB-dependent receptor
PE794_08640	COG1629	transport
PE794_08670	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PE794_08675	COG3545	Serine hydrolase
PE794_08710	COG1215	transferase activity, transferring glycosyl groups
PE794_08710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PE794_08740	COG1119	ATPase activity
PE794_08755	COG1739	Uncharacterized protein family UPF0029
PE794_08760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PE794_08765	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
PE794_08770	COG1970	mechanosensitive ion channel activity
PE794_08775	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PE794_08780	COG0321	lipoyl(octanoyl) transferase activity
PE794_08785	COG2921	Belongs to the UPF0250 family
PE794_08790	COG1686	Belongs to the peptidase S11 family
PE794_08795	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PE794_08800	COG0772	Belongs to the SEDS family
PE794_08805	COG0768	penicillin binding
PE794_08810	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PE794_08815	COG0799	negative regulation of ribosome biogenesis
PE794_08830	COG0765	amino acid transport
PE794_08835	COG3681	Belongs to the UPF0597 family
PE794_08840	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PE794_08850	COG3691	Protein conserved in bacteria
PE794_08900	COG0831	urea catabolic process
PE794_08910	COG1122	ATPase activity
PE794_08915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PE794_08920	COG0310	cobalt ion transport
PE794_08925	COG0310	cobalt ion transport
PE794_08930	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
PE794_08935	COG0583	DNA-binding transcription factor activity
PE794_08945	COG0471	metal ion transport
PE794_08945	COG0490	domain, Protein
PE794_08950	COG3722	fumarate hydratase activity
PE794_08965	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PE794_08970	COG1349	DNA-binding transcription factor activity
PE794_08985	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
PE794_08995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PE794_09000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PE794_09005	COG2900	Belongs to the SlyX family
PE794_09010	COG0545	Peptidyl-prolyl cis-trans isomerase
PE794_09015	COG2964	Protein conserved in bacteria
PE794_09020	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PE794_09030	COG2168	tRNA wobble position uridine thiolation
PE794_09060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PE794_09065	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PE794_09070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PE794_09075	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PE794_09100	COG0357	Ribosomal RNA small subunit methyltransferase G
PE794_09105	COG0445	tRNA wobble uridine modification
PE794_09110	COG0561	phosphatase activity
PE794_09115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE794_09120	COG3012	SEC-C Motif Domain Protein
PE794_09130	COG3716	PTS system mannose fructose sorbose family IID component
PE794_09135	COG3715	PTS system
PE794_09140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
PE794_09140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PE794_09145	COG2610	gluconate transmembrane transporter activity
PE794_09150	COG3265	gluconokinase activity
PE794_09155	COG1609	Transcriptional regulator
PE794_09160	COG1609	Transcriptional regulator
PE794_09175	COG1172	Belongs to the binding-protein-dependent transport system permease family
PE794_09180	COG1879	ABC-type sugar transport system periplasmic component
PE794_09185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PE794_09190	COG0243	molybdopterin cofactor binding
PE794_09195	COG0437	4 iron, 4 sulfur cluster binding
PE794_09200	COG3302	dmso reductase anchor subunit
PE794_09205	COG3381	protein complex oligomerization
PE794_09210	COG2221	Nitrite and sulphite reductase 4Fe-4S
PE794_09210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PE794_09235	COG1349	DNA-binding transcription factor activity
PE794_09240	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
PE794_09245	COG1070	Carbohydrate kinase
PE794_09250	COG4154	Belongs to the RbsD FucU family
PE794_09255	COG0235	Class ii aldolase
PE794_09260	COG0738	Major facilitator superfamily
PE794_09265	COG1454	alcohol dehydrogenase
PE794_09270	COG3477	response to acidic pH
PE794_09275	COG0765	amino acid transport
PE794_09285	COG1126	abc transporter atp-binding protein
PE794_09290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PE794_09310	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
PE794_09335	COG3623	hexulose-6-phosphate isomerase
PE794_09340	COG0235	Class ii aldolase
PE794_09345	COG0545	Peptidyl-prolyl cis-trans isomerase
PE794_09370	COG4783	chaperone-mediated protein folding
PE794_09375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PE794_09385	COG0758	DNA mediated transformation
PE794_09390	COG1297	OPT oligopeptide transporter protein
PE794_09405	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PE794_09415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PE794_09420	COG0081	regulation of translation
PE794_09425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PE794_09430	COG0222	ribosome binding
PE794_09500	COG1487	ribonuclease activity
PE794_09515	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PE794_09520	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PE794_09530	COG0346	lactoylglutathione lyase activity
PE794_09535	COG1194	a g-specific adenine glycosylase
PE794_09540	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PE794_09545	COG0741	lytic transglycosylase activity
PE794_09570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PE794_09575	COG0737	Belongs to the 5'-nucleotidase family
PE794_09580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PE794_09585	COG0606	chelatase, subunit chli
PE794_09595	COG2267	carboxylic ester hydrolase activity
PE794_09600	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PE794_09610	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PE794_09620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PE794_09625	COG0363	glucosamine-6-phosphate deaminase activity
PE794_09630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PE794_09645	COG0051	transcription antitermination factor activity, RNA binding
PE794_09650	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PE794_09655	COG0088	Forms part of the polypeptide exit tunnel
PE794_09660	COG0089	rRNA binding
PE794_09665	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PE794_09670	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PE794_09675	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PE794_09680	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PE794_09685	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PE794_09690	COG0255	Belongs to the universal ribosomal protein uL29 family
PE794_09695	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PE794_09705	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PE794_09710	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PE794_09715	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PE794_09720	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PE794_09725	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PE794_09730	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PE794_09735	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PE794_09740	COG1841	ribosomal large subunit assembly
PE794_09745	COG0200	Binds to the 23S rRNA
PE794_09750	COG0201	protein transport
PE794_09760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PE794_09765	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PE794_09770	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PE794_09775	COG0202	RNA polymerase activity
PE794_09785	COG0228	four-way junction DNA binding
PE794_09790	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PE794_09795	COG0336	Belongs to the RNA methyltransferase TrmD family
PE794_09800	COG0335	large ribosomal subunit rRNA binding
PE794_09805	COG2850	peptidyl-arginine hydroxylation
PE794_09810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PE794_09815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PE794_09820	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PE794_09860	COG2852	Protein conserved in bacteria
PE794_09885	COG2832	Protein of unknown function (DUF454)
PE794_09890	COG1215	transferase activity, transferring glycosyl groups
PE794_09895	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PE794_09905	COG0084	hydrolase, TatD family'
PE794_09920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PE794_09930	COG0470	DNA polymerase III
PE794_09935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PE794_09940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PE794_09960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PE794_09965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PE794_09970	COG0254	rRNA binding
PE794_09975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PE794_09980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PE794_09985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PE794_09990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PE794_10000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PE794_10015	COG0442	prolyl-tRNA aminoacylation
PE794_10025	COG1595	DNA-templated transcription, initiation
PE794_10030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PE794_10040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PE794_10065	COG2502	aspartate--ammonia ligase
PE794_10070	COG1522	sequence-specific DNA binding
PE794_10075	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
PE794_10080	COG3161	chorismate lyase activity
PE794_10140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PE794_10150	COG4208	sulfate ABC transporter
PE794_10155	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PE794_10165	COG1304	FMN binding
PE794_10175	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PE794_10185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PE794_10190	COG2995	paraquat-inducible protein a
PE794_10195	COG1305	Transglutaminase-like
PE794_10205	COG2608	mercury ion transmembrane transporter activity
PE794_10210	COG1979	alcohol dehydrogenase
PE794_10215	COG0583	DNA-binding transcription factor activity
PE794_10220	COG2171	N-acyltransferase activity
PE794_10225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PE794_10235	COG0511	ligase activity, forming carbon-carbon bonds
PE794_10240	COG0439	Biotin carboxylase
PE794_10245	COG1763	Mo-molybdopterin cofactor biosynthetic process
PE794_10250	COG3084	Protein conserved in bacteria
PE794_10255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PE794_10265	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PE794_10265	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PE794_10275	COG1876	peptidase activity
PE794_10280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PE794_10285	COG1393	Belongs to the ArsC family
PE794_10295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PE794_10300	COG0564	pseudouridine synthase activity
PE794_10310	COG0668	transmembrane transport
PE794_10315	COG0439	Biotin carboxylase
PE794_10325	COG1025	Belongs to the peptidase M16 family
PE794_10330	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PE794_10355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PE794_10360	COG1067	ATP-dependent peptidase activity
PE794_10365	COG3120	sequence-specific DNA binding
PE794_10370	COG0180	Tryptophanyl-tRNA synthetase
PE794_10390	COG0730	response to heat
PE794_10405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PE794_10415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PE794_10420	COG2116	formate transmembrane transporter activity
PE794_10445	COG0443	Heat shock 70 kDa protein
PE794_10450	COG1070	Carbohydrate kinase
PE794_10455	COG2115	Belongs to the xylose isomerase family
PE794_10460	COG4213	ABC transporter substrate-binding protein
PE794_10465	COG1129	ABC transporter
PE794_10470	COG4214	carbohydrate transport
PE794_10475	COG1609	Transcriptional regulator
PE794_10475	COG2207	Transcriptional regulator
PE794_10480	COG3590	peptidase
PE794_10490	COG4145	pantothenate transmembrane transporter activity
PE794_10495	COG3924	membrane
PE794_10500	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
PE794_10505	COG2853	Lipoprotein
PE794_10510	COG0676	glucose-6-phosphate 1-epimerase activity
PE794_10525	COG0726	polysaccharide deacetylase
PE794_10525	COG1649	PFAM Uncharacterised BCR, COG1649
PE794_10530	COG1215	transferase activity, transferring glycosyl groups
PE794_10540	COG0149	triose-phosphate isomerase activity
PE794_10550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PE794_10555	COG1238	metal cluster binding
PE794_10570	COG1388	LysM domain
PE794_10570	COG4942	peptidase
PE794_10575	COG2818	Glycosylase
PE794_10585	COG0700	Nucleoside recognition
PE794_10590	COG3366	ferrous iron transmembrane transporter activity
PE794_10595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PE794_10600	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PE794_10605	COG0594	ribonuclease P activity
PE794_10610	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PE794_10615	COG0174	glutamine synthetase
PE794_10620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PE794_10625	COG0494	nUDIX hydrolase
PE794_10655	COG1490	D-aminoacyl-tRNA deacylase activity
PE794_10660	COG1295	ribonuclease BN
PE794_10665	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PE794_10670	COG1629	transport
PE794_10670	COG4771	TonB-dependent receptor
PE794_10680	COG1629	transport
PE794_10680	COG4771	TonB-dependent receptor
PE794_10700	COG1064	alcohol dehydrogenase
PE794_10710	COG1923	regulation of RNA biosynthetic process
PE794_10715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PE794_10725	COG1694	Mazg nucleotide pyrophosphohydrolase
PE794_10740	COG1309	transcriptional regulator
PE794_10750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PE794_10755	COG2003	Belongs to the UPF0758 family
PE794_10760	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PE794_10765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PE794_10780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PE794_10785	COG0076	glutamate decarboxylase activity
PE794_10790	COG0425	Belongs to the sulfur carrier protein TusA family
PE794_10795	COG2391	methyltransferase activity
PE794_10800	COG3085	chromosome segregation
PE794_10820	COG0598	Magnesium transport protein CorA
PE794_10825	COG2226	methyltransferase
PE794_10835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PE794_10840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PE794_10845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PE794_10850	COG0805	protein transport
PE794_10870	COG1114	Component of the transport system for branched-chain amino acids
PE794_10875	COG1028	Short-chain dehydrogenase reductase Sdr
PE794_10880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PE794_10885	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PE794_10890	COG0142	geranyltranstransferase activity
PE794_10900	COG0431	NADPH-dependent FMN reductase
PE794_10905	COG2259	Doxx family
PE794_10910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PE794_10915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PE794_10920	COG0697	spore germination
PE794_10925	COG4783	chaperone-mediated protein folding
PE794_10935	COG1040	competence protein
PE794_10950	COG0456	acetyltransferase
PE794_10955	COG0513	Belongs to the DEAD box helicase family
PE794_10965	COG0747	negative chemotaxis
PE794_10975	COG1584	GPR1 FUN34 yaaH family protein
PE794_10980	COG1120	ATPase activity
PE794_11015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PE794_11020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PE794_11040	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PE794_11055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PE794_11055	COG0140	phosphoribosyl-ATP diphosphatase activity
PE794_11060	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PE794_11065	COG0024	Methionine aminopeptidase
PE794_11080	COG1621	beta-fructofuranosidase activity
PE794_11085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PE794_11095	COG4591	ABC-type transport system involved in lipoprotein release permease component
PE794_11100	COG1136	(ABC) transporter
PE794_11105	COG4591	ABC-type transport system involved in lipoprotein release permease component
PE794_11110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family