locus-tag	class	description
DRF63_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
DRF63_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DRF63_00020	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DRF63_00025	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
DRF63_00040	ENOG4105ERU	peptidase
DRF63_00060	ENOG4105CJN	penicillin-binding protein
DRF63_00065	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
DRF63_00070	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
DRF63_00080	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
DRF63_00085	ENOG4105CNI	cell division protein FtsW
DRF63_00095	ENOG4105DFU	Cell wall formation (By similarity)
DRF63_00100	ENOG4105CPF	Cell wall formation (By similarity)
DRF63_00110	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
DRF63_00115	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DRF63_00120	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DRF63_00125	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DRF63_00130	ENOG4108JQ5	ABC transporter
DRF63_00135	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DRF63_00140	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DRF63_00165	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
DRF63_00170	ENOG4105C3G	gtp-binding protein
DRF63_00185	ENOG4108XTF	Outer Membrane Lipoprotein
DRF63_00190	ENOG4105NBI	YecM protein
DRF63_00195	ENOG4105C75	arginyL-tRNA synthetase
DRF63_00205	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
DRF63_00210	ENOG4105C2N	RNA methyltransferase TrmH family group 3
DRF63_00215	ENOG4105JIM	Phosphatidylserine synthase
DRF63_00220	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DRF63_00225	ENOG4105DTN	riboflavin biosynthesis protein ribF
DRF63_00230	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
DRF63_00235	ENOG4108VVQ	metallophosphoesterase
DRF63_00240	ENOG41065U4	response regulator
DRF63_00250	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
DRF63_00255	ENOG4105DFA	alanine racemase domain protein
DRF63_00265	ENOG4105CI3	gtp-binding protein typa
DRF63_00270	ENOG41090BQ	Glutaredoxin
DRF63_00280	ENOG4105DSJ	YicC domain protein
DRF63_00285	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
DRF63_00290	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
DRF63_00295	ENOG4105WH1	Two component transcriptional regulator luxr family
DRF63_00305	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
DRF63_00340	ENOG4105DEF	Extracellular solute-binding protein, family 5
DRF63_00345	ENOG4105DEF	Extracellular solute-binding protein, family 5
DRF63_00350	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DRF63_00355	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DRF63_00360	ENOG4105C3U	ABC transporter
DRF63_00365	ENOG4108JQ7	(ABC) transporter
DRF63_00380	ENOG4105M4H	endoribonuclease L-psp
DRF63_00385	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DRF63_00390	ENOG4105M2J	Glutaredoxin
DRF63_00395	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
DRF63_00400	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
DRF63_00410	ENOG4105M15	transport protein ExbD
DRF63_00415	ENOG4105M8K	biopolymer transport protein
DRF63_00420	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
DRF63_00425	ENOG4107QR8	Thioredoxin
DRF63_00430	ENOG4105VDH	Dihydroxyacetone kinase
DRF63_00435	ENOG4108UTZ	Dihydroxyacetone kinase
DRF63_00440	ENOG4105CMT	Dihydroxyacetone kinase
DRF63_00445	ENOG4105C3M	thioredoxin reductase
DRF63_00450	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
DRF63_00455	ENOG4105VP5	Bacterial protein of unknown function (DUF937)
DRF63_00465	ENOG4108R99	pseudouridine synthase
DRF63_00475	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
DRF63_00480	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
DRF63_00495	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
DRF63_00510	ENOG4105C01	Dihydroxy-acid dehydratase
DRF63_00515	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
DRF63_00525	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
DRF63_00530	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
DRF63_00535	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DRF63_00540	ENOG4105DVI	reductase, NrfD
DRF63_00555	ENOG4105C2W	permease
DRF63_00565	ENOG4105CK7	Sodium proline symporter
DRF63_00570	ENOG41069M3	Transcriptional regulator
DRF63_00575	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
DRF63_00590	ENOG4105E07	UPF0149 protein
DRF63_00595	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
DRF63_00600	ENOG4105R2J	Conserved Protein
DRF63_00605	ENOG4105K70	DNA-binding protein
DRF63_00610	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
DRF63_00625	ENOG4105VEQ	Cold shock protein
DRF63_00630	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
DRF63_00635	ENOG4105CN1	protease
DRF63_00640	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
DRF63_00645	ENOG4105EAQ	(twin-arginine translocation) pathway signal
DRF63_00650	ENOG4105C5X	domain protein
DRF63_00665	ENOG4105K59	histidine triad (HIT) protein
DRF63_00670	ENOG4105CC5	ABC transporter
DRF63_00675	ENOG4105CC5	ABC transporter
DRF63_00680	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DRF63_00685	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DRF63_00690	ENOG4105ETT	transcriptional Regulator, LysR family
DRF63_00695	ENOG4105PAD	Hydrolase
DRF63_00700	ENOG4107R11	Transcriptional regulator
DRF63_00710	ENOG4105HDK	L-asparaginase
DRF63_00735	ENOG4107VHA	regulatoR
DRF63_00740	ENOG4107QQ0	gntp family
DRF63_00745	ENOG4105BZW	Glycerate kinase
DRF63_00750	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
DRF63_00755	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
DRF63_00760	ENOG4105EWT	decarboxylase family
DRF63_00765	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
DRF63_00775	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DRF63_00780	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
DRF63_00785	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DRF63_00790	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DRF63_00795	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DRF63_00800	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DRF63_00805	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DRF63_00810	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
DRF63_00815	ENOG4105CJ2	(LipO)protein
DRF63_00830	ENOG4105D8G	Major Facilitator superfamily
DRF63_00835	ENOG4105II7	pyrroline-5-carboxylate reductase
DRF63_00845	ENOG4107VXZ	Hydrolase
DRF63_00860	ENOG4105DGN	Electron transport complex
DRF63_00865	ENOG4108R3D	Electron transport complex
DRF63_00870	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
DRF63_00875	ENOG4105EN6	Membrane
DRF63_00880	ENOG4105D6A	Electron transport complex
DRF63_00895	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
DRF63_00905	ENOG4105DP9	ABC transporter
DRF63_00910	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DRF63_00915	ENOG4105DJ0	Poly(A) Polymerase
DRF63_00920	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DRF63_00930	ENOG4107H52	Dicarboxylate transport
DRF63_00940	ENOG4108UYE	Lactoylglutathione lyase
DRF63_00945	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
DRF63_00950	ENOG4105K3M	)-transporter
DRF63_00955	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
DRF63_00960	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DRF63_00965	ENOG4105DKP	glycosyl transferase, family 9
DRF63_00970	ENOG4105CA9	Pyruvate kinase
DRF63_00975	ENOG4108BY2	phosphohistidine phosphatase
DRF63_00980	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
DRF63_00985	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
DRF63_00990	ENOG4105C8J	)-transporter
DRF63_00995	ENOG4105DFE	Dna adenine methylase
DRF63_01000	ENOG4105D49	3-dehydroquinate synthase
DRF63_01005	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
DRF63_01010	ENOG4108JQC	penicillin-binding protein 1A
DRF63_01035	ENOG4105E4G	Type IV pilus
DRF63_01040	ENOG4107YIM	Involved in the transcription termination process (By similarity)
DRF63_01045	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
DRF63_01050	ENOG4108ZAI	phosphatidylglycerophosphatase a
DRF63_01055	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
DRF63_01060	ENOG4105EIB	trna rrna methyltransferase
DRF63_01065	ENOG4105ECY	inositol monophosphatase
DRF63_01070	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DRF63_01085	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DRF63_01135	ENOG4106B0W	Curli production assembly transport component CsgG
DRF63_01145	ENOG4107Y60	(LipO)protein
DRF63_01150	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
DRF63_01155	ENOG41082NX	50s ribosomal protein l35
DRF63_01160	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
DRF63_01165	ENOG4108QD6	
DRF63_01180	ENOG4105C37	(CBS) domain
DRF63_01185	ENOG4108W1A	pseudouridine synthase
DRF63_01190	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DRF63_01195	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
DRF63_01200	ENOG4108UJU	UPF0301 protein
DRF63_01205	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
DRF63_01215	ENOG4105M85	Bola protein
DRF63_01240	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DRF63_01250	ENOG4105M6F	mutator MutT protein
DRF63_01255	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DRF63_01265	ENOG4105C8Y	Acetylornithine aminotransferase
DRF63_01275	ENOG4108MVK	Receptor
DRF63_01280	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
DRF63_01285	ENOG4105C6T	cysteine synthase
DRF63_01290	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DRF63_01295	ENOG4105CFH	Aspartokinase
DRF63_01300	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DRF63_01305	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DRF63_01310	ENOG4107QYX	exodeoxyribonuclease v alpha
DRF63_01340	ENOG4105CIN	aminoacyl-histidine dipeptidase
DRF63_01345	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
DRF63_01350	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
DRF63_01355	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DRF63_01365	ENOG4108Z1B	Cyclase dehydrase
DRF63_01370	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
DRF63_01375	ENOG4105E0C	molybdate abc transporter
DRF63_01380	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
DRF63_01385	ENOG4105E3A	(ABC) transporter
DRF63_01390	ENOG4105DA5	(ABC) transporter
DRF63_01395	ENOG4107QMP	dna polymerase iii subunits gamma and tau
DRF63_01400	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
DRF63_01410	ENOG4105KME	endoribonuclease L-psp
DRF63_01415	ENOG4105C6T	cysteine synthase
DRF63_01420	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
DRF63_01425	ENOG4105DIK	(ABC) transporter
DRF63_01435	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
DRF63_01440	ENOG4108MN8	Membrane
DRF63_01445	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
DRF63_01455	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DRF63_01460	ENOG4108RE7	deoxyribonuclease
DRF63_01465	ENOG4105C4R	Atp-dependent dna helicase
DRF63_01470	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DRF63_01475	ENOG4105F38	ABC transporter, permease
DRF63_01480	ENOG4105D38	putrescine abc transporter
DRF63_01500	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DRF63_01530	ENOG4105C5H	ABC transporter
DRF63_01535	ENOG4105CUZ	uba thif-type nad fad binding protein
DRF63_01545	ENOG4105C4M	(Ubiquinol oxidase) subunit I
DRF63_01550	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
DRF63_01565	ENOG4107YD3	Thioesterase
DRF63_01570	ENOG4105E02	MotA TolQ exbB proton channel
DRF63_01585	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
DRF63_01590	ENOG4105KCK	Peptidoglycan-associated lipoprotein
DRF63_01600	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
DRF63_01605	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
DRF63_01610	ENOG4106K28	UPF0283 membrane protein
DRF63_01615	ENOG4105C5H	ABC transporter
DRF63_01625	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DRF63_01630	ENOG4105D06	uba thif-type nad fad binding protein
DRF63_01640	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DRF63_01645	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
DRF63_01655	ENOG4105D3G	Pseudouridine synthase
DRF63_01660	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
DRF63_01665	ENOG4105D6S	protein involved in catabolism of external DNA
DRF63_01670	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DRF63_01680	ENOG4105C28	cystathionine
DRF63_01685	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
DRF63_01700	ENOG4105C9A	Phoh family
DRF63_01735	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
DRF63_01765	ENOG4105D0A	hydroxylase
DRF63_01785	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
DRF63_01795	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
DRF63_01800	ENOG4108IUZ	ABC transporter
DRF63_01805	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
DRF63_01815	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
DRF63_01820	ENOG4108WV1	Pfam:DUF477
DRF63_01830	ENOG4108V0P	LemA family
DRF63_01840	ENOG4105DM4	PTS System
DRF63_01845	ENOG4105DE4	1-phosphofructokinase
DRF63_01850	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
DRF63_01860	ENOG4108ESZ	Glycogen debranching enzyme
DRF63_01865	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DRF63_01870	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
DRF63_01875	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
DRF63_01890	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DRF63_01905	ENOG4105I08	Pseudouridine synthase
DRF63_01910	ENOG4105C2C	drug resistance transporter, Bcr CflA
DRF63_01920	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
DRF63_01930	ENOG4107TT5	NLP P60 protein
DRF63_01940	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
DRF63_01945	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
DRF63_01950	ENOG4108MJ5	VirK protein
DRF63_01960	ENOG4105CQ7	ATP-dependent helicase
DRF63_01965	ENOG4108VMM	UPF0756 membrane protein
DRF63_01975	ENOG4107RUE	extracellular solute-binding protein family 1
DRF63_01980	ENOG4107QI1	Mate efflux family protein
DRF63_01985	ENOG4107QKA	exodeoxyribonuclease V beta
DRF63_01990	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
DRF63_01995	ENOG4108JU5	Magnesium and cobalt efflux protein
DRF63_02000	ENOG4108Q67	UPF0319 protein
DRF63_02005	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DRF63_02010	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DRF63_02015	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
DRF63_02020	ENOG4105CXY	transporter
DRF63_02025	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
DRF63_02030	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
DRF63_02035	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
DRF63_02040	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
DRF63_02045	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
DRF63_02050	ENOG4108R6K	riboflavin synthase, subunit alpha
DRF63_02065	ENOG4108RRZ	Transcription elongation factor GreB
DRF63_02070	ENOG4105C2X	Arabinose 5-phosphate isomerase
DRF63_02080	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
DRF63_02085	ENOG4105C09	Bile acid
DRF63_02090	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
DRF63_02095	ENOG4105DQF	Hydrolase
DRF63_02100	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DRF63_02105	ENOG4105EMN	RNA polymerase sigma factor
DRF63_02110	ENOG41069PW	sigma-e factor negative regulatory protein
DRF63_02120	ENOG4105CEY	Amp-dependent synthetase and ligase
DRF63_02125	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
DRF63_02130	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
DRF63_02135	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
DRF63_02140	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
DRF63_02145	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
DRF63_02160	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
DRF63_02170	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DRF63_02185	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
DRF63_02190	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DRF63_02200	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DRF63_02205	ENOG4105DZP	Membrane-associated zinc metalloprotease
DRF63_02210	ENOG4105KNE	Phosphatidate cytidylyltransferase
DRF63_02215	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DRF63_02220	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DRF63_02230	ENOG4105EYK	Phosphatidylglycerophosphatase B
DRF63_02235	ENOG4105HBR	Rna-binding protein
DRF63_02240	ENOG4106WTF	Glycosyl transferase, family 2
DRF63_02245	ENOG41061WM	D-Alanyl-D-Alanine
DRF63_02250	ENOG4105M5K	heptosyltransferase
DRF63_02260	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DRF63_02265	ENOG4105E96	Colicin v production protein
DRF63_02270	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
DRF63_02280	ENOG4105D82	Glutamate dehydrogenase
DRF63_02285	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
DRF63_02295	ENOG4105KME	endoribonuclease L-psp
DRF63_02300	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
DRF63_02320	ENOG4105E0X	reductase
DRF63_02325	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DRF63_02330	ENOG4105DFF	Rod shape-determining protein mreb
DRF63_02335	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
DRF63_02345	ENOG4105D1H	recombination factor protein RarA
DRF63_02350	ENOG4105FAV	ABC, transporter
DRF63_02355	ENOG4105E7A	Glutamine amidotransferase
DRF63_02360	ENOG4105DWV	Homoserine O-trans-acetylase
DRF63_02365	ENOG4107GZ4	SanA protein
DRF63_02380	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
DRF63_02385	ENOG4107QR9	Iron-sulfur cluster binding protein
DRF63_02390	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
DRF63_02395	ENOG4105DAA	L-lactate
DRF63_02400	ENOG4108SAU	DNA-binding protein H-ns
DRF63_02405	ENOG4107S6Z	Na H antiporter
DRF63_02410	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
DRF63_02415	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
DRF63_02425	ENOG4108MJ5	VirK protein
DRF63_02430	ENOG4105C7S	Dehydrogenase
DRF63_02435	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
DRF63_02440	ENOG4105FDK	ABC transporter
DRF63_02445	ENOG4105DR5	peptidase
DRF63_02450	ENOG4105T95	Thiol disulfide interChange protein
DRF63_02455	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
DRF63_02465	ENOG4108K4B	hydrolase
DRF63_02470	ENOG4105BZU	Histidine kinase
DRF63_02480	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DRF63_02490	ENOG4105CKU	formyltetrahydrofolate synthetase
DRF63_02495	ENOG4108ZZ3	UPF0260 protein
DRF63_02500	ENOG4105EMU	Dehydrogenase
DRF63_02505	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DRF63_02515	ENOG4105X5T	
DRF63_02525	ENOG4105C2M	dna polymerase I
DRF63_02530	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
DRF63_02535	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
DRF63_02540	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
DRF63_02570	ENOG41080HT	Transcriptional regulator, arsr family
DRF63_02585	ENOG41080C8	DUF218 domain
DRF63_02590	ENOG4105C6K	Malic enzyme
DRF63_02595	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
DRF63_02690	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DRF63_02695	ENOG4105RDA	repressor
DRF63_02725	ENOG4108MXB	Protein of unknown function (DUF968)
DRF63_02805	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DRF63_02885	ENOG41065CD	Exported protein
DRF63_02890	ENOG4105D7X	high-affinity nickel-transporter
DRF63_02895	ENOG4105BZG	amino acid carrier protein
DRF63_02900	ENOG4108YI8	ABC transporter
DRF63_02905	ENOG4108YI8	ABC transporter
DRF63_02915	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
DRF63_02920	ENOG4105D06	uba thif-type nad fad binding protein
DRF63_02925	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DRF63_02930	ENOG4105D41	biosynthesis protein thiH
DRF63_02935	ENOG4105ETU	transcriptional activator (TenA
DRF63_02940	ENOG4107Z6I	Thiamine biosynthesis protein
DRF63_02955	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
DRF63_02960	ENOG4105C3F	Signal peptidase i
DRF63_02965	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
DRF63_02970	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
DRF63_02975	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
DRF63_03050	ENOG4105C1J	atp-dependent rna helicase
DRF63_03060	ENOG4105D7A	ATP-binding protein
DRF63_03065	ENOG4105C4Y	ABC transporter
DRF63_03070	ENOG4107RCV	ABC transporter, permease
DRF63_03095	ENOG4108I6E	Sulfatase
DRF63_03100	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DRF63_03105	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
DRF63_03110	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DRF63_03125	ENOG4108Z6B	deaminase
DRF63_03130	ENOG4105C1J	atp-dependent rna helicase
DRF63_03135	ENOG4105RT1	May be involved in cell division (By similarity)
DRF63_03140	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DRF63_03145	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DRF63_03160	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
DRF63_03175	ENOG4105E68	Sulfatase
DRF63_03180	ENOG4105YDX	UPF0352 protein
DRF63_03185	ENOG4105Y7M	Transcriptional regulator, TetR family
DRF63_03190	ENOG410624X	efflux transporter, rnd family, mfp subunit
DRF63_03195	ENOG4105BZS	acriflavin resistance protein
DRF63_03210	ENOG4105TWJ	Domain of unknown function (DUF1919)
DRF63_03215	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
DRF63_03230	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DRF63_03235	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
DRF63_03240	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DRF63_03245	ENOG4105E0U	tyrosine-specific transport protein
DRF63_03250	ENOG4105E0U	tyrosine-specific transport protein
DRF63_03260	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
DRF63_03265	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DRF63_03275	ENOG4105D1Q	UPF0246 protein
DRF63_03285	ENOG41076HS	cation diffusion facilitator family transporter
DRF63_03290	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
DRF63_03295	ENOG4107R6U	sodium dicarboxylate symporter
DRF63_03300	ENOG4108RCM	Nitroreductase
DRF63_03305	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
DRF63_03310	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
DRF63_03315	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
DRF63_03320	ENOG4108QBX	(LipO)protein
DRF63_03330	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
DRF63_03335	ENOG4105E2R	ROK family
DRF63_03340	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
DRF63_03345	ENOG4105EW9	transcriptional regulator AsnC family
DRF63_03350	ENOG4105CNU	cell division protein FtsK
DRF63_03355	ENOG4105CGZ	zinc metallopeptidase
DRF63_03360	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DRF63_03365	ENOG41072GX	Peptidase M22 Glycoprotease
DRF63_03370	ENOG4107104	thymidine kinase
DRF63_03375	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
DRF63_03380	ENOG4105CBT	Fructose-1,6-bisphosphatase
DRF63_03385	ENOG4107QNR	UPF0135 protein
DRF63_03390	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DRF63_03395	ENOG4105E0F	Histidine kinase
DRF63_03400	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
DRF63_03405	ENOG4105DXN	mazG family
DRF63_03415	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DRF63_03425	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
DRF63_03430	ENOG4105CHV	Transcription elongation factor NusA
DRF63_03435	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DRF63_03440	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
DRF63_03445	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DRF63_03450	ENOG4105CVE	Lytic murein transglycosylase
DRF63_03455	ENOG4107EPN	Domain of unknown function (DUF1508)
DRF63_03460	ENOG4108DNC	Involved in acetate metabolism (By similarity)
DRF63_03470	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
DRF63_03490	ENOG4108J3C	UTP-glucose-1-phosphate uridylyltransferase
DRF63_03500	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
DRF63_03515	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
DRF63_03520	ENOG4105KB2	stringent starvation protein b
DRF63_03525	ENOG4107MKT	Stringent starvation protein a
DRF63_03530	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
DRF63_03535	ENOG4105HDK	L-asparaginase
DRF63_03540	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
DRF63_03545	ENOG4105CGF	Aromatic amino acid aminotransferase
DRF63_03550	ENOG4107RAQ	aminopeptidase
DRF63_03560	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
DRF63_03565	ENOG410650H	(LipO)protein
DRF63_03570	ENOG4105DBE	peroxidase
DRF63_03580	ENOG4105DB7	PHP domain protein
DRF63_03590	ENOG4105CJB	Exodeoxyribonuclease I
DRF63_03600	ENOG4105C5S	asparaginyl-tRNA synthetase
DRF63_03605	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
DRF63_03615	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DRF63_03620	ENOG4105CX6	glutaminyL-tRNA synthetase
DRF63_03630	ENOG4107SC1	transglycosylase
DRF63_03635	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
DRF63_03640	ENOG4105C28	cystathionine
DRF63_03645	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
DRF63_03650	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
DRF63_03655	ENOG4105M08	Membrane
DRF63_03660	ENOG4105CXG	d-lactate dehydrogenase
DRF63_03665	ENOG4107QY8	reductase
DRF63_03670	ENOG4105CUW	cytochrome C-TYPE protein
DRF63_03680	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DRF63_03685	ENOG4105M00	molybdopterin converting factor, subunit 1
DRF63_03690	ENOG4108ZAF	Molybdopterin
DRF63_03695	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
DRF63_03700	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
DRF63_03705	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DRF63_03710	ENOG4105CC0	LysR family Transcriptional regulator
DRF63_03720	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
DRF63_03735	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
DRF63_03740	ENOG4105C0D	helicase
DRF63_03760	ENOG4105QEK	Transcriptional regulator
DRF63_03765	ENOG4108R66	Conserved Protein
DRF63_03770	ENOG4105C9X	ppx gppa phosphatase
DRF63_03780	ENOG4105CFH	Aspartokinase
DRF63_03785	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
DRF63_03790	ENOG4105VNG	YcgL domain-containing protein
DRF63_03795	ENOG4105CDU	Replicative dna helicase
DRF63_03805	ENOG4105DHS	permease protein
DRF63_03810	ENOG4105CM4	permease protein
DRF63_03815	ENOG4108IPW	abc transporter atp-binding protein
DRF63_03820	ENOG4107IX6	phosphate transport regulator
DRF63_03825	ENOG4105CJ3	phosphate transporter
DRF63_03840	ENOG4105NSG	hemerythrin hhe cation binding domain protein
DRF63_03845	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
DRF63_03855	ENOG4105VEQ	Cold shock protein
DRF63_03860	ENOG41077A9	carbonic anhydrase
DRF63_03865	ENOG4105C7K	acetolactate synthase
DRF63_03870	ENOG4108ZP8	Acetolactate synthase small subunit
DRF63_03875	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
DRF63_03880	ENOG4105N42	UPF0307 protein
DRF63_03890	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
DRF63_03895	ENOG4108UQV	Membrane
DRF63_03900	ENOG4108ZPB	UPF0306 protein
DRF63_03905	ENOG4108ZJT	translation initiation factor, Sui1
DRF63_03910	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
DRF63_03915	ENOG4105CFV	Tetratricopeptide repeat protein
DRF63_03920	ENOG4105Q4A	inner membrane protein yciS
DRF63_03925	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
DRF63_03930	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DRF63_03935	ENOG4105CAT	Cytidine monophosphate kinase
DRF63_03940	ENOG4105C0H	protease
DRF63_03955	ENOG4108IYH	Dna topoisomerase
DRF63_03960	ENOG4105G6Z	alkaline phosphatase
DRF63_03965	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
DRF63_03975	ENOG4105EGS	Mechanosensitive ion channel
DRF63_03980	ENOG4105EGS	Mechanosensitive ion channel
DRF63_03985	ENOG4105CEY	Amp-dependent synthetase and ligase
DRF63_03990	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
DRF63_03995	ENOG4105EV9	Alpha Beta Hydrolase
DRF63_04000	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
DRF63_04005	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
DRF63_04020	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
DRF63_04025	ENOG4105VAW	lrga family
DRF63_04030	ENOG41067MG	lrgb family
DRF63_04035	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
DRF63_04050	ENOG4105DVA	methyltransferase
DRF63_04060	ENOG4105CHW	UPF0052 protein
DRF63_04070	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
DRF63_04075	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
DRF63_04085	ENOG41080IJ	Diacylglycerol kinase
DRF63_04090	ENOG4105CGH	5'-nucleotidase
DRF63_04115	ENOG4107QN2	dihydrolipoyl dehydrogenase
DRF63_04120	ENOG4107QSN	dihydrolipoamide acetyltransferase
DRF63_04125	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
DRF63_04130	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
DRF63_04135	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DRF63_04150	ENOG4105BZ1	(ABC) transporter
DRF63_04155	ENOG41067MG	lrgb family
DRF63_04165	ENOG4105DVT	helicase
DRF63_04175	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DRF63_04180	ENOG4108UUM	single-stranded DNA-binding protein
DRF63_04210	ENOG4105EA8	2-Nitropropane dioxygenase
DRF63_04220	ENOG4105UNS	Pfam:DUF419
DRF63_04225	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
DRF63_04230	ENOG4108EU3	peptide transport system, permease
DRF63_04240	ENOG4108EVY	peptide transport periplasmic protein
DRF63_04245	ENOG4108JU8	Transcriptional regulator
DRF63_04250	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
DRF63_04255	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
DRF63_04260	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
DRF63_04280	ENOG4105E0M	Sulfatase
DRF63_04285	ENOG4105QVC	MOSC domain-containing protein
DRF63_04295	ENOG4105CTB	Polyprenyl synthetase
DRF63_04305	ENOG4105CRK	lysyL-tRNA synthetase
DRF63_04310	ENOG4105C03	ribonuclease
DRF63_04315	ENOG4105DDY	UPF0142 protein ycaO
DRF63_04325	ENOG4107QMH	DNA methylase
DRF63_04330	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
DRF63_04340	ENOG4105CA3	membrane-bound lytic murein transglycosylase
DRF63_04360	ENOG4105VT2	5-hydroxyisourate hydrolase
DRF63_04370	ENOG4108VD1	dedA family
DRF63_04375	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DRF63_04385	ENOG4105E98	transcriptional regulator DeoR family
DRF63_04390	ENOG4107QTF	adenylosuccinate lyase
DRF63_04395	ENOG41075W9	High frequency lysogenization protein HflD homolog
DRF63_04400	ENOG4108JJ8	(ABC) transporter
DRF63_04405	ENOG4108JJ9	ABC, transporter
DRF63_04410	ENOG4105MA0	exported protein
DRF63_04415	ENOG4105CFU	surface antigen
DRF63_04420	ENOG4105PXI	polysaccharide deacetylase
DRF63_04425	ENOG41063SB	peptidase
DRF63_04430	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DRF63_04440	ENOG4105DBI	uridine monophosphokinase
DRF63_04445	ENOG4105DHP	deoxycytidine triphosphate deaminase
DRF63_04455	ENOG4105D0S	secretion protein (HlyD
DRF63_04460	ENOG4105CJ1	ABC, transporter
DRF63_04465	ENOG4105CMI	transporter
DRF63_04475	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
DRF63_04480	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
DRF63_04485	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
DRF63_04495	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
DRF63_04500	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DRF63_04505	ENOG4105CSA	Coproporphyrinogen iii oxidase
DRF63_04510	ENOG4107QSI	ABC, transporter
DRF63_04525	ENOG4108JQ7	(ABC) transporter
DRF63_04540	ENOG4105SYT	Methylenetetrahydrofolate reductase
DRF63_04545	ENOG4105DEF	Extracellular solute-binding protein, family 5
DRF63_04550	ENOG4105C44	Serine transporter
DRF63_04555	ENOG4105EJQ	L-serine dehydratase
DRF63_04565	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DRF63_04575	ENOG4105WP7	tRNA pseudouridine synthase C
DRF63_04580	ENOG4105DR9	pseudouridine synthase
DRF63_04595	ENOG4105I7R	Adenylate cyclase
DRF63_04600	ENOG4105CM6	amino acid regulated cytosolic protein
DRF63_04605	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
DRF63_04615	ENOG4105CH2	amidohydrolase
DRF63_04630	ENOG4105C8T	Leucyl-tRNA synthetase
DRF63_04640	ENOG4105DJF	DNA polymerase III, delta' subunit
DRF63_04645	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
DRF63_04650	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
DRF63_04660	ENOG4105D7Q	type ii secretion system
DRF63_04665	ENOG4107QHF	type ii secretion system protein e
DRF63_04675	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
DRF63_04685	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
DRF63_04690	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
DRF63_04695	ENOG4105EJ9	Membrane
DRF63_04700	ENOG4105CSM	endonuclease III
DRF63_04725	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
DRF63_04730	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DRF63_04735	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DRF63_04740	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DRF63_04745	ENOG4108MG3	formate dehydrogenase
DRF63_04750	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
DRF63_04780	ENOG4105D1S	lipid A biosynthesis
DRF63_04785	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
DRF63_04795	ENOG4105EUJ	GTP cyclohydrolase i
DRF63_04800	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
DRF63_04810	ENOG4108UW5	maltose o-acetyltransferase
DRF63_04825	ENOG4105ZIA	Phage protein gp16
DRF63_04835	ENOG41065S5	
DRF63_04845	ENOG4105IKI	host-nuclease inhibitor protein
DRF63_04940	ENOG4105CF2	Mu-like prophage FluMu protein GP28
DRF63_05045	ENOG4107H6E	
DRF63_05050	ENOG4105ENX	hydrolase
DRF63_05055	ENOG4105EQ2	LysR family Transcriptional regulator
DRF63_05060	ENOG4105D01	(LipO)protein
DRF63_05065	ENOG4105D01	(LipO)protein
DRF63_05070	ENOG4108UMI	ABC transporter, permease
DRF63_05075	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
DRF63_05090	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
DRF63_05095	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DRF63_05105	ENOG4105UGU	tonB-dependent Receptor
DRF63_05130	ENOG4105WVQ	Fe-S assembly protein IscX
DRF63_05135	ENOG4108ZIT	Ferredoxin, 2FE-2S
DRF63_05145	ENOG4108RF1	Protein of unknown function DUF2625
DRF63_05155	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
DRF63_05160	ENOG4108Z4V	iron-sulfur cluster assembly
DRF63_05165	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
DRF63_05170	ENOG4105C3J	Cysteine desulfurase
DRF63_05175	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
DRF63_05180	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
DRF63_05185	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DRF63_05190	ENOG4105BZU	Histidine kinase
DRF63_05195	ENOG4108TZV	Membrane
DRF63_05200	ENOG4108DG9	Smr protein MutS2
DRF63_05205	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
DRF63_05210	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
DRF63_05215	ENOG4105HSA	Protein of unknown function (DUF452)
DRF63_05220	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DRF63_05225	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DRF63_05230	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
DRF63_05235	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
DRF63_05240	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
DRF63_05275	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
DRF63_05280	ENOG4105DC1	bifunctional purine biosynthesis protein purh
DRF63_05290	ENOG4105CKT	filamentous hemagglutinin
DRF63_05310	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
DRF63_05315	ENOG4105D4P	Coproporphyrinogen iii oxidase
DRF63_05330	ENOG4105D0C	transport protein
DRF63_05335	ENOG4105D6U	Sodium Glutamate Symporter
DRF63_05345	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
DRF63_05350	ENOG4105K9H	YciI-like protein
DRF63_05355	ENOG4105NAU	thioesterase Superfamily protein
DRF63_05370	ENOG4105PQ6	UPF0208 membrane protein
DRF63_05380	ENOG4105D3Y	Na H antiporter
DRF63_05385	ENOG4105CGK	Exodeoxyribonuclease III
DRF63_05390	ENOG4105EMY	transcriptional regulator
DRF63_05400	ENOG4105W1T	Glycosyl Transferase
DRF63_05415	ENOG4105VFB	Binds the 23S rRNA (By similarity)
DRF63_05420	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DRF63_05430	ENOG4105CH6	catalase
DRF63_05440	ENOG4107RN3	metallophosphoesterase
DRF63_05445	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DRF63_05450	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DRF63_05455	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
DRF63_05465	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
DRF63_05470	ENOG4105CNT	hydrolase family 2
DRF63_05485	ENOG4105D1F	ATP-binding protein
DRF63_05495	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
DRF63_05500	ENOG4105EIN	peptidylprolyl cis-trans isomerase
DRF63_05505	ENOG4105EEQ	Na H antiporter
DRF63_05510	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
DRF63_05515	ENOG4105CKW	Inner membrane protein yedI
DRF63_05520	ENOG410601J	HemY protein
DRF63_05525	ENOG4105ECF	c-methyltransferase
DRF63_05530	ENOG41076E6	Uroporphyrinogen-III Synthase
DRF63_05535	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
DRF63_05540	ENOG4108EKI	Dehydrogenase
DRF63_05555	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DRF63_05560	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
DRF63_05565	ENOG4105D9N	nucleoside
DRF63_05570	ENOG4108VW9	Membrane
DRF63_05575	ENOG4108UHU	Aldolase
DRF63_05580	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
DRF63_05585	ENOG4105D2H	Uronic isomerase
DRF63_05595	ENOG4107YCY	Transcriptional regulator
DRF63_05605	ENOG4105E0X	reductase
DRF63_05610	ENOG4108RYC	glycosyltransferase
DRF63_05615	ENOG4108RJ9	Glycosyl transferase, family 2
DRF63_05625	ENOG41068D6	Glycosyltransferase
DRF63_05635	ENOG4108ZPC	Polysaccharide pyruvyl transferase
DRF63_05640	ENOG41080C8	DUF218 domain
DRF63_05645	ENOG4105C25	Primosomal protein n'
DRF63_05650	ENOG4105CQC	Prephenate dehydratase
DRF63_05655	ENOG4105DGW	oligopeptidase A
DRF63_05660	ENOG4105F1A	Pyruvate formate-lyase
DRF63_05665	ENOG4105C6N	Formate acetyltransferase
DRF63_05670	ENOG4105TMB	Formate nitrite transporter
DRF63_05675	ENOG4105W39	Membrane
DRF63_05680	ENOG4105D0M	Protease HtpX homolog
DRF63_05690	ENOG4105DWU	Membrane
DRF63_05695	ENOG4105E4F	Isochorismate synthase
DRF63_05700	ENOG4105CHM	Aminotransferase
DRF63_05705	ENOG4105DTR	rard protein
DRF63_05710	ENOG4105DTR	rard protein
DRF63_05725	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
DRF63_05735	ENOG4108DMF	Cytochrome C biogenesis protein
DRF63_05740	ENOG4107QX9	Thiol disulfide interChange protein
DRF63_05745	ENOG4105DA4	cytochrome c-type biogenesis protein
DRF63_05750	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
DRF63_05755	ENOG4107T0K	Adenylate cyclase
DRF63_05760	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DRF63_05775	ENOG4105WXI	Bacterial OB fold (BOF) protein
DRF63_05790	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
DRF63_05795	ENOG4105DHQ	Histidine kinase
DRF63_05800	ENOG4108UUE	Transcriptional regulator
DRF63_05805	ENOG4105VIE	preprotein translocase, subunit YajC
DRF63_05810	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DRF63_05815	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DRF63_05820	ENOG41090A1	ferritin
DRF63_05825	ENOG41090A1	ferritin
DRF63_05830	ENOG4105C7N	Xanthine uracil vitamin C permease
DRF63_05835	ENOG4108Z03	MAF-like protein
DRF63_05850	ENOG4105HEI	LysR family (Transcriptional regulator
DRF63_05865	ENOG4105E4P	ATPase (AAA
DRF63_05880	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DRF63_05885	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
DRF63_05890	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DRF63_05900	ENOG4105EPW	hflc protein
DRF63_05905	ENOG4107QJR	hflk protein
DRF63_05910	ENOG4105K63	Thioredoxin
DRF63_05930	ENOG4105D5Q	Arginine ornithine antiporter
DRF63_05935	ENOG4105D5Q	Arginine ornithine antiporter
DRF63_05945	ENOG4105CWC	Acetylornithine deacetylase
DRF63_05950	ENOG4105EIF	outer membrane protein W
DRF63_05955	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DRF63_05960	ENOG4105D6J	arsenicaL-resistance protein
DRF63_05965	ENOG4105K89	arsenate reductase
DRF63_05975	ENOG4108IJ0	Aspartate ammonia-lyase
DRF63_05985	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
DRF63_05990	ENOG41069UX	Beta-N-acetyl-hexosaminidase
DRF63_06000	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
DRF63_06005	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
DRF63_06030	ENOG4108M8S	permease YjgP YjgQ family protein
DRF63_06035	ENOG4108K5H	permease YjgP YjgQ family protein
DRF63_06040	ENOG4105C0B	DNA polymerase III (alpha subunit)
DRF63_06045	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
DRF63_06050	ENOG4105E55	glycerol-3-phosphate acyltransferase
DRF63_06055	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
DRF63_06060	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
DRF63_06065	ENOG4105EE5	Membrane protein terC
DRF63_06070	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
DRF63_06075	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
DRF63_06080	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DRF63_06090	ENOG4108VBH	Uncharacterized protein conserved in bacteria (DUF2251)
DRF63_06095	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DRF63_06100	ENOG4105XQ6	frataxin-like protein
DRF63_06105	ENOG4107J0A	lipopolysaccharide biosynthetic process
DRF63_06110	ENOG4107J0A	lipopolysaccharide biosynthetic process
DRF63_06115	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DRF63_06120	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DRF63_06125	ENOG4105C34	Pseudouridine synthase
DRF63_06130	ENOG4108VTV	Inherit from NOG: Membrane
DRF63_06135	ENOG4105CTQ	phosphohexokinase
DRF63_06140	ENOG4105C9B	Cysteine desulfurase
DRF63_06145	ENOG4105KK6	nuclease
DRF63_06150	ENOG4105BZG	amino acid carrier protein
DRF63_06155	ENOG4105DSF	transport protein
DRF63_06165	ENOG4105CFP	Peptidase U32
DRF63_06170	ENOG4105PF3	O-Antigen polymerase
DRF63_06175	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
DRF63_06185	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
DRF63_06190	ENOG4105K8N	protein family UPF0079, ATPase
DRF63_06195	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
DRF63_06200	ENOG4107QP8	phosphohexose isomerase
DRF63_06205	ENOG4105W0Z	cytoplasmic protein
DRF63_06225	ENOG4105E2X	shikimate dehydrogenase
DRF63_06235	ENOG4108WI1	Dna topoisomerase
DRF63_06240	ENOG41060QA	UPF0267 protein
DRF63_06245	ENOG4105Y3E	Modulates RecA activity (By similarity)
DRF63_06250	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
DRF63_06260	ENOG4105CRQ	synthase (Component I)
DRF63_06265	ENOG4105CGY	Dna recombination protein
DRF63_06270	ENOG4105DDQ	anthranilate synthase
DRF63_06280	ENOG4105C9M	aspartyl-trna synthetase
DRF63_06285	ENOG4108TIT	dATP pyrophosphohydrolase
DRF63_06300	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
DRF63_06305	ENOG4107RAN	Peptidase, M16
DRF63_06315	ENOG4107QPK	)-transporter
DRF63_06320	ENOG4105DZ2	Transcriptional regulator
DRF63_06325	ENOG4106ZV1	Transferrin binding protein-like solute binding protein
DRF63_06330	ENOG4105FE9	pseudouridine synthase
DRF63_06335	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
DRF63_06345	ENOG4105EZR	dyp-type peroxidase family protein
DRF63_06350	ENOG4105CRQ	synthase (Component I)
DRF63_06355	ENOG4105DDQ	anthranilate synthase
DRF63_06365	ENOG4105DMQ	Methyltransferase
DRF63_06370	ENOG4105RHG	
DRF63_06375	ENOG4105Z2P	Protein of unknown function (DUF465)
DRF63_06390	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
DRF63_06400	ENOG4105C12	Phosphoribosylglycinamide synthetase
DRF63_06410	ENOG4105N21	Membrane
DRF63_06420	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
DRF63_06425	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
DRF63_06430	ENOG4105CHH	sulfate transporter
DRF63_06440	ENOG4105D9R	oxidoreductase
DRF63_06445	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
DRF63_06460	ENOG4105EXG	Transcriptional regulator
DRF63_06490	ENOG4108ZHJ	Organic hydroperoxide resistance protein
DRF63_06520	ENOG4105CF7	AraC family transcriptional regulator
DRF63_06530	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DRF63_06535	ENOG4105DEN	Luciferase family
DRF63_06540	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DRF63_06545	ENOG4108RCM	Nitroreductase
DRF63_06550	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
DRF63_06560	ENOG4105C4W	S-formylglutathione hydrolase
DRF63_06585	ENOG4105C94	Transporter
DRF63_06600	ENOG4108NKP	c4-dicarboxylate transporter malic acid transport protein
DRF63_06605	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
DRF63_06620	ENOG4105BZ1	(ABC) transporter
DRF63_06625	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
DRF63_06630	ENOG4105DY2	Paraquat-inducible protein b
DRF63_06635	ENOG41090R7	Ferric uptake
DRF63_06640	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
DRF63_06645	ENOG4105NNH	LexA regulated protein
DRF63_06650	ENOG4108Z66	YbaK ebsC protein
DRF63_06655	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
DRF63_06660	ENOG4105C7N	Xanthine uracil vitamin C permease
DRF63_06665	ENOG41090EX	DsrE family
DRF63_06670	ENOG4105CBX	hi0933 family
DRF63_06675	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
DRF63_06680	ENOG41062Z9	Membrane
DRF63_06685	ENOG4105EAC	phosphoserine phosphatase
DRF63_06700	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
DRF63_06705	ENOG41061ZR	Transcriptional regulator
DRF63_06710	ENOG4107W52	maltose operon periplasmic protein
DRF63_06715	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
DRF63_06720	ENOG4108IJ9	(ABC) transporter
DRF63_06725	ENOG4107FKK	extracellular solute-binding protein family 1
DRF63_06730	ENOG4105D56	permease protein
DRF63_06735	ENOG4105EG2	ABC transporter, permease
DRF63_06740	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
DRF63_06750	ENOG4105EYA	deoxyribonuclease
DRF63_06755	ENOG4105DC8	reductase
DRF63_06760	ENOG4108TEB	UPF0114 protein
DRF63_06765	ENOG4108TVJ	Nitroreductase
DRF63_06785	ENOG4105D2N	Aldolase
DRF63_06790	ENOG4105BZA	Phosphoglycerate kinase
DRF63_06795	ENOG4105C8P	)-transporter
DRF63_06800	ENOG4105C8P	)-transporter
DRF63_06805	ENOG4105C8P	)-transporter
DRF63_06810	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DRF63_06815	ENOG4105BZU	Histidine kinase
DRF63_06820	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DRF63_06825	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DRF63_06835	ENOG4105C8U	phosphate abc transporter
DRF63_06840	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
DRF63_06845	ENOG4108Z6Z	Transcriptional regulator
DRF63_06860	ENOG4105C59	p-type ATPase
DRF63_06865	ENOG4105E1F	short-chain dehydrogenase reductase
DRF63_06870	ENOG41069NU	Nitroreductase
DRF63_06875	ENOG4105D07	Signal peptide peptidase, SppA
DRF63_06880	ENOG41083KI	ribonuclease, T2
DRF63_06885	ENOG4105GPY	SprT protein
DRF63_06890	ENOG4105CEP	NADH dehydrogenase
DRF63_06895	ENOG4105BZM	domain protein
DRF63_06900	ENOG41090FY	type IV pilus biogenesis stability protein PilW
DRF63_06905	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DRF63_06940	ENOG4105VTW	prevent-host-death family
DRF63_06945	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
DRF63_06950	ENOG4105W49	UPF0434 protein
DRF63_06960	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
DRF63_06965	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DRF63_06970	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
DRF63_06985	ENOG4108JDX	DNA polymerase iii, epsilon subunit
DRF63_06990	ENOG4105C5H	ABC transporter
DRF63_07010	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DRF63_07015	ENOG4105VFK	BolA family
DRF63_07025	ENOG4105E3I	toluene tolerance
DRF63_07030	ENOG4107PE3	Mammalian cell entry related domain protein
DRF63_07035	ENOG4105CY3	ABC transporter, permease
DRF63_07040	ENOG4105DHJ	ABC, transporter
DRF63_07045	ENOG4105C0H	protease
DRF63_07050	ENOG4105ECP	epimerase
DRF63_07070	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DRF63_07080	ENOG4105EYM	Major Facilitator superfamily
DRF63_07085	ENOG4105CMR	udp-glucose 4-epimerase
DRF63_07110	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
DRF63_07125	ENOG4105D2S	major facilitator superfamily
DRF63_07130	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
DRF63_07135	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
DRF63_07140	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
DRF63_07145	ENOG4107RK2	ADP-ribose diphosphatase NudE
DRF63_07150	ENOG4105VEJ	Heat shock protein
DRF63_07160	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
DRF63_07165	ENOG4105DBV	ornithine carbamoyltransferase
DRF63_07170	ENOG4105C5B	carbamate kinase
DRF63_07175	ENOG4105C5Y	PTS System
DRF63_07180	ENOG4107T0D	ABC, transporter
DRF63_07185	ENOG4106SMU	thiamine transporter membrane protein
DRF63_07190	ENOG4105KZ7	phosphocarrier protein hpr
DRF63_07195	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
DRF63_07200	ENOG4105C5Y	PTS System
DRF63_07210	ENOG4105C4R	Atp-dependent dna helicase
DRF63_07215	ENOG4107RSS	Hydrogenase accessory protein HypB
DRF63_07220	ENOG4105CQS	hydrogenase expression formation protein HypD
DRF63_07225	ENOG4105C45	hydrogenase expression formation protein (HypE)
DRF63_07230	ENOG4105C8H	hydrogenase maturation protein Hypf
DRF63_07235	ENOG4105E3S	small subunit
DRF63_07240	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DRF63_07245	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
DRF63_07250	ENOG4105DPX	Hydrogenase, large subunit
DRF63_07255	ENOG4108USZ	hydrogenase
DRF63_07260	ENOG4108WGS	hydrogenase 2-specific chaperone
DRF63_07305	ENOG4108JA2	transcriptioN-repair coupling factor
DRF63_07310	ENOG4105CD8	aminopeptidase N
DRF63_07315	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
DRF63_07320	ENOG4107ZVW	dihydroneopterin aldolase
DRF63_07325	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
DRF63_07330	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
DRF63_07335	ENOG4105CAK	Cell division ATP-binding protein ftsE
DRF63_07340	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DRF63_07345	ENOG4106H78	methyltransferase
DRF63_07350	ENOG4105XW2	UPF0263 protein
DRF63_07355	ENOG4107UWN	reductase
DRF63_07365	ENOG4105DMR	ABC, transporter
DRF63_07370	ENOG4105GBT	ABC transporter
DRF63_07375	ENOG4106PMH	Extracellular solute-binding protein family 3
DRF63_07380	ENOG4105E5Z	arginine transporter ATP-binding subunit
DRF63_07385	ENOG4108V1U	phospholipid-binding protein
DRF63_07395	ENOG4105KDP	XRE family
DRF63_07405	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
DRF63_07410	ENOG4108BPE	-transporting atpase
DRF63_07415	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
DRF63_07420	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
DRF63_07425	ENOG41082RQ	UPF0102 protein
DRF63_07430	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
DRF63_07435	ENOG4105W4M	Transport-associated protein
DRF63_07460	ENOG4105DA4	cytochrome c-type biogenesis protein
DRF63_07470	ENOG4105X3C	heme exporter protein
DRF63_07475	ENOG41060IM	Heme exporter protein
DRF63_07480	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
DRF63_07485	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
DRF63_07490	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
DRF63_07530	ENOG4107QSA	Oxaloacetate decarboxylase
DRF63_07535	ENOG4105D9Q	decarboxylase (Beta subunit)
DRF63_07540	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
DRF63_07545	ENOG4105CA0	peroxidase
DRF63_07550	ENOG4105VZ9	UPF0235 protein
DRF63_07555	ENOG4108VIA	integral membrane protein
DRF63_07560	ENOG41090ED	Protein with unknown function (DUF469)
DRF63_07565	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
DRF63_07570	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DRF63_07575	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
DRF63_07580	ENOG4105VGS	50s ribosomal protein l32
DRF63_07585	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
DRF63_07590	ENOG4106KVJ	cytochrome C assembly protein
DRF63_07595	ENOG4108JU6	CBS domain protein
DRF63_07600	ENOG4105C8J	)-transporter
DRF63_07610	ENOG4108EQA	pts system
DRF63_07615	ENOG4105ETZ	PTS System
DRF63_07620	ENOG4105F3R	pts system mannose fructose sorbose family iid
DRF63_07625	ENOG4108NK4	UPF0266 membrane protein
DRF63_07630	ENOG4105EIP	mannose-6-phosphate isomerase
DRF63_07640	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
DRF63_07645	ENOG4108JJA	ABC, transporter
DRF63_07650	ENOG4107V48	Hemolysin-type calcium-binding
DRF63_07655	ENOG41090Q8	at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP
DRF63_07660	ENOG4105C4Y	ABC transporter
DRF63_07670	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DRF63_07675	ENOG4105DFU	Cell wall formation (By similarity)
DRF63_07690	ENOG4105EHV	domain protein
DRF63_07695	ENOG4105C5Q	Transcriptional regulator
DRF63_07700	ENOG4105EJ2	Transcriptional regulator
DRF63_07705	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DRF63_07710	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
DRF63_07720	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DRF63_07725	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DRF63_07730	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
DRF63_07735	ENOG4105VCC	30S ribosomal protein S21
DRF63_07740	ENOG4105D3Q	Sugar transferase
DRF63_07745	ENOG4108KBE	Glycosyl transferase, family 2
DRF63_07750	ENOG4105H63	Glycosyl transferase, family 2
DRF63_07775	ENOG4105EY8	ABC transporter
DRF63_07780	ENOG4105MFV	ABC-2 type transporter
DRF63_07785	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
DRF63_07795	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
DRF63_07800	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
DRF63_07805	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
DRF63_07810	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
DRF63_07815	ENOG4108R96	Methyltransferase, YaeB family
DRF63_07825	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DRF63_07830	ENOG4108YZY	peptidylprolyl cis-trans isomerase
DRF63_07835	ENOG4105C7B	Threonine dehydratase
DRF63_07840	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DRF63_07845	ENOG4105E66	phosphoriboisomerase A
DRF63_07850	ENOG4108JQ1	Dehydrogenase
DRF63_07860	ENOG4105NXV	High-affinity zinc uptake system protein
DRF63_07870	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
DRF63_07880	ENOG4105C03	ribonuclease
DRF63_07895	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
DRF63_07910	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DRF63_07915	ENOG4108BGM	Quinol dehydrogenase periplasmic component
DRF63_07920	ENOG4105GXZ	Ferredoxin-type protein NapH
DRF63_07925	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
DRF63_07930	ENOG4105CUW	cytochrome C-TYPE protein
DRF63_07940	ENOG4105KA0	thioesterase Superfamily protein
DRF63_07945	ENOG4105CQB	FAD linked oxidase domain protein
DRF63_07950	ENOG4105W44	ompa motb domain protein
DRF63_07955	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
DRF63_07960	ENOG4105C2J	ABC transporter
DRF63_07965	ENOG4108HWV	)-transporter
DRF63_07990	ENOG4108IQE	Amp-dependent synthetase and ligase
DRF63_07995	ENOG4107QM2	Aldo Keto reductase
DRF63_08000	ENOG4105KZW	UPF0381 protein
DRF63_08005	ENOG4105CIC	tryptophan-specific transport protein
DRF63_08015	ENOG4105D9M	gamma-glutamylcysteine synthetase
DRF63_08025	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DRF63_08030	ENOG4107QTH	restriction modification system DNA specificity domain
DRF63_08055	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
DRF63_08060	ENOG4108UBT	opacity-associated protein
DRF63_08070	ENOG4105XA0	heptosyltransferase ii
DRF63_08075	ENOG4105D16	lipopolysaccharide heptosyltransferase i
DRF63_08080	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
DRF63_08085	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DRF63_08090	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DRF63_08095	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DRF63_08120	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
DRF63_08130	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
DRF63_08135	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
DRF63_08150	ENOG4105VUC	UPF0237 protein
DRF63_08155	ENOG4105C2I	pirin domain protein
DRF63_08160	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
DRF63_08175	ENOG4105EM2	membrane
DRF63_08180	ENOG4108Z5K	methylglyoxal synthase
DRF63_08185	ENOG4105D98	threonine synthase
DRF63_08195	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DRF63_08205	ENOG4107YB6	acetyltransferase, (GNAT) family
DRF63_08210	ENOG4105MYG	DNA polymerase iii, chi subunit
DRF63_08215	ENOG4108WZM	domain protein
DRF63_08225	ENOG4107YZP	Rhodanese domain protein
DRF63_08230	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
DRF63_08235	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DRF63_08240	ENOG4105D7W	serine acetyltransferase
DRF63_08245	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DRF63_08270	ENOG4105CS9	pantothenic acid kinase
DRF63_08275	ENOG4107QX9	Thiol disulfide interChange protein
DRF63_08280	ENOG4108M1T	Cytochrome c-type biogenesis protein
DRF63_08285	ENOG4108M1T	Cytochrome c-type biogenesis protein
DRF63_08290	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
DRF63_08295	ENOG4108YZA	Nitrogen regulatory protein pii
DRF63_08300	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
DRF63_08305	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
DRF63_08310	ENOG410863D	Flavinator of succinate dehydrogenase
DRF63_08320	ENOG4105D4P	Coproporphyrinogen iii oxidase
DRF63_08325	ENOG4108K3A	Glutathione S-transferase
DRF63_08330	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DRF63_08340	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
DRF63_08345	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
DRF63_08350	ENOG4105E33	succinate dehydrogenase
DRF63_08355	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
DRF63_08360	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
DRF63_08365	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
DRF63_08370	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
DRF63_08385	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
DRF63_08390	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DRF63_08395	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DRF63_08410	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
DRF63_08415	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DRF63_08425	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DRF63_08485	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
DRF63_08490	ENOG4105DAD	Could be involved in ECA polysaccharide chain elongation (By similarity)
DRF63_08500	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
DRF63_08505	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
DRF63_08510	ENOG4105EGZ	biosynthesis protein
DRF63_08515	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DRF63_08525	ENOG4108IJ1	Dehydrogenase
DRF63_08530	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
DRF63_08540	ENOG4105ESV	Glycosyl transferase, family 4
DRF63_08555	ENOG4105CJR	Integral membrane protein (MviN
DRF63_08560	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
DRF63_08565	ENOG4105C1A	potassium transporter peripheral membrane
DRF63_08570	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DRF63_08575	ENOG4105EM7	Selenocysteine-specific translation elongation factor
DRF63_08590	ENOG4105QTB	Flavodoxin
DRF63_08600	ENOG4105CMG	Carbohydrate kinase
DRF63_08615	ENOG4108MVK	Receptor
DRF63_08625	ENOG4105M8F	Biopolymer transport protein exbD tolR
DRF63_08640	ENOG4105DWU	Membrane
DRF63_08650	ENOG4105DG4	malate L-lactate dehydrogenase
DRF63_08655	ENOG4105MJ9	esterase
DRF63_08690	ENOG4107VDP	teichoic acid biosynthesis
DRF63_08720	ENOG4105DKW	ABC transporter
DRF63_08735	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
DRF63_08740	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
DRF63_08745	ENOG4108RR8	protoporphyrinogen oxidase
DRF63_08750	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
DRF63_08755	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
DRF63_08760	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
DRF63_08770	ENOG4105DZ1	carboxypeptidase
DRF63_08780	ENOG4105CNI	cell division protein FtsW
DRF63_08785	ENOG4105CJN	penicillin-binding protein
DRF63_08790	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
DRF63_08795	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
DRF63_08810	ENOG4105E5Q	amino acid AbC transporter
DRF63_08815	ENOG4105CEM	UPF0597 protein
DRF63_08820	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
DRF63_08825	ENOG410814C	multidrug resistance protein
DRF63_08830	ENOG4105KZW	UPF0381 protein
DRF63_08850	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
DRF63_08855	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
DRF63_08860	ENOG4105HFU	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
DRF63_08870	ENOG4105CQM	Urea amidohydrolase subunit alpha
DRF63_08880	ENOG4108YZ9	Urea amidohydrolase subunit gamma
DRF63_08890	ENOG4108JJB	ABC transporter
DRF63_08900	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
DRF63_08905	ENOG4108A51	
DRF63_08910	ENOG4105UZ0	ABC-type Co2 transport system, periplasmic component
DRF63_08915	ENOG4108M0I	Transcriptional regulator
DRF63_08925	ENOG4107QWE	)-transporter
DRF63_08930	ENOG4105E61	Mannitol repressor protein
DRF63_08940	ENOG4105CTS	PTS system mannitol-specific
DRF63_08945	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DRF63_08950	ENOG410804X	Transcriptional regulator
DRF63_08965	ENOG4106YJS	accessory processing protein
DRF63_08975	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
DRF63_08985	ENOG4105VRX	Protein slyX homolog
DRF63_08990	ENOG4108V1T	peptidylprolyl cis-trans isomerase
DRF63_08995	ENOG4105WWK	YheO domain protein
DRF63_09000	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
DRF63_09005	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
DRF63_09040	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
DRF63_09045	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
DRF63_09050	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
DRF63_09055	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DRF63_09065	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DRF63_09080	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
DRF63_09085	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
DRF63_09090	ENOG410667J	hydrolase
DRF63_09095	ENOG4105EAB	amino acid AbC transporter
DRF63_09100	ENOG4105K5B	UPF0225 protein
DRF63_09110	ENOG4105F3R	pts system mannose fructose sorbose family iid
DRF63_09115	ENOG4105ETZ	PTS System
DRF63_09120	ENOG4108EQA	pts system
DRF63_09125	ENOG4105C6Z	Gluconate
DRF63_09130	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
DRF63_09135	ENOG4105DIQ	Transcriptional regulator
DRF63_09140	ENOG4105ETE	Transcriptional regulator (LacI family
DRF63_09155	ENOG4105CNN	ABC, transporter
DRF63_09160	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
DRF63_09165	ENOG4108RVA	ribokinase
DRF63_09170	ENOG4107QY8	reductase
DRF63_09175	ENOG4105QAX	Iron-sulfur
DRF63_09180	ENOG4107KGK	dmso reductase anchor subunit
DRF63_09185	ENOG4108NEM	leader-binding protein dmsD
DRF63_09190	ENOG4105N1P	Ferredoxin-type protein
DRF63_09210	ENOG4108ETH	Formylglycinamide ribotide synthetase
DRF63_09215	ENOG4107EDW	L-fucose operon activator
DRF63_09220	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
DRF63_09225	ENOG4105CMG	Carbohydrate kinase
DRF63_09230	ENOG4105NWF	RbsD or FucU transport
DRF63_09235	ENOG4107W7X	Aldolase
DRF63_09240	ENOG4105EDR	glucose galactose transporter
DRF63_09245	ENOG4105C0A	alcohol dehydrogenase
DRF63_09250	ENOG4105R3P	Inner membrane protein yagU
DRF63_09255	ENOG4105E5Q	amino acid AbC transporter
DRF63_09265	ENOG4105CDA	abc transporter atp-binding protein
DRF63_09270	ENOG4105CT1	(ABC) transporter
DRF63_09275	ENOG4105E12	capsule polysaccharide
DRF63_09315	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
DRF63_09320	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
DRF63_09325	ENOG4108V1T	peptidylprolyl cis-trans isomerase
DRF63_09350	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
DRF63_09360	ENOG4105C79	DNA protecting protein DprA
DRF63_09365	ENOG4105EPD	Oligopeptide transporter, Opt family
DRF63_09380	ENOG4105PM1	preprotein translocase subunit SecE
DRF63_09385	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
DRF63_09390	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DRF63_09395	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
DRF63_09400	ENOG4108VZM	50s ribosomal protein L10
DRF63_09405	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
DRF63_09485	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
DRF63_09490	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
DRF63_09500	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
DRF63_09505	ENOG4105CEN	a g-specific adenine glycosylase
DRF63_09510	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
DRF63_09515	ENOG4105E4C	Lytic transglycosylase catalytic
DRF63_09540	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DRF63_09545	ENOG4105CGH	5'-nucleotidase
DRF63_09550	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
DRF63_09555	ENOG4105C0P	Mg chelatase subunit ChlI
DRF63_09560	ENOG4106IIQ	Outer membrane lipoprotein
DRF63_09565	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
DRF63_09570	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
DRF63_09580	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
DRF63_09585	ENOG4105EVU	fructokinase
DRF63_09590	ENOG4108MB0	N-acetylneuraminate lyase
DRF63_09595	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
DRF63_09600	ENOG4105CE4	GlcNAc 6-P deacetylase
DRF63_09605	ENOG4105C9Q	fumarate hydratase class II
DRF63_09620	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DRF63_09625	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DRF63_09630	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DRF63_09635	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DRF63_09640	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DRF63_09645	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DRF63_09650	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
DRF63_09655	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
DRF63_09660	ENOG41083MP	50s ribosomal protein l29
DRF63_09665	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DRF63_09675	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
DRF63_09680	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DRF63_09685	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
DRF63_09690	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DRF63_09695	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DRF63_09700	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
DRF63_09705	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DRF63_09710	ENOG4105VPB	50S ribosomal protein L30
DRF63_09715	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DRF63_09720	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
DRF63_09730	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DRF63_09735	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
DRF63_09740	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DRF63_09745	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DRF63_09755	ENOG4105K5M	30s ribosomal protein S16
DRF63_09760	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
DRF63_09765	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
DRF63_09770	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
DRF63_09775	ENOG4105EZE	Cupin 4 family protein
DRF63_09780	ENOG4105S10	periplasmic binding protein
DRF63_09785	ENOG4105EHG	Permease protein
DRF63_09790	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
DRF63_09815	ENOG4108J2R	molybdopterin oxidoreductase
DRF63_09830	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
DRF63_09855	ENOG4105WD1	Membrane
DRF63_09860	ENOG4105K64	Glycosyl transferase, family 2
DRF63_09865	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
DRF63_09870	ENOG4105RX8	Protein of unknown function (DUF1523)
DRF63_09875	ENOG4105F8V	Hydrolase, tatD family
DRF63_09885	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DRF63_09890	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
DRF63_09895	ENOG4107ZJM	MltA-interacting protein MipA
DRF63_09900	ENOG4107QRG	dna polymerase iii
DRF63_09905	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DRF63_09910	ENOG4105HHA	aminodeoxychorismate lyase
DRF63_09930	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DRF63_09935	ENOG4105DJV	ribulose-phosphate 3-epimerase
DRF63_09940	ENOG4105NRA	50s ribosomal protein l31 type b
DRF63_09945	ENOG4105YK5	50S ribosomal protein L36
DRF63_09950	ENOG4105BZ4	penicillin-binding protein
DRF63_09955	ENOG4108IPT	Naphthoate synthase
DRF63_09960	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DRF63_09970	ENOG4105CB5	ATP-dependent DNA helicase recG
DRF63_09985	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DRF63_09995	ENOG4108WQI	RNA Polymerase
DRF63_10000	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
DRF63_10005	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
DRF63_10010	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DRF63_10015	ENOG4105CXY	transporter
DRF63_10035	ENOG4105CU9	asparagine synthetase A
DRF63_10040	ENOG4108VVK	transcriptional Regulator, AsnC
DRF63_10045	ENOG4108I5U	Uridine phosphorylase
DRF63_10050	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
DRF63_10080	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
DRF63_10085	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
DRF63_10110	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
DRF63_10115	ENOG4108I5D	sulfate abc transporter
DRF63_10120	ENOG4105ECW	sulfate abc transporter
DRF63_10125	ENOG4108IJ6	ABC transporter
DRF63_10135	ENOG4105DMF	Dehydrogenase
DRF63_10140	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
DRF63_10145	ENOG4105D4A	Cell wall formation (By similarity)
DRF63_10155	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DRF63_10160	ENOG4105H2K	paraquat-inducible protein a
DRF63_10165	ENOG4108KS2	transglutaminase domain protein
DRF63_10175	ENOG410681U	heavy metal transport detoxification protein
DRF63_10180	ENOG4107QW4	alcohol dehydrogenase
DRF63_10185	ENOG4105EMY	transcriptional regulator
DRF63_10190	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
DRF63_10195	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
DRF63_10200	ENOG4108ST3	glycosyltransferase
DRF63_10205	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
DRF63_10210	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DRF63_10215	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
DRF63_10225	ENOG4108Z33	Thiol disulfide Interchange Protein
DRF63_10235	ENOG41063M6	Cell Division Protein
DRF63_10235	ENOG41063M6	Cell Division Protein
DRF63_10250	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DRF63_10255	ENOG4105KUZ	arsenate reductase
DRF63_10265	ENOG4105EEI	dihydropteroate synthase
DRF63_10270	ENOG4105EI2	Pseudouridine synthase
DRF63_10285	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DRF63_10295	ENOG4107QXK	peptidase
DRF63_10300	ENOG4105DSY	exodeoxyribonuclease V, gamma
DRF63_10325	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
DRF63_10330	ENOG4105DAN	ATP-dependent protease
DRF63_10335	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
DRF63_10340	ENOG4105C31	Tryptophanyl-tRNA synthetase
DRF63_10360	ENOG4105HF0	Membrane
DRF63_10375	ENOG4105F0N	pyrophosphate phospho-hydrolase
DRF63_10385	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
DRF63_10390	ENOG4105TMB	Formate nitrite transporter
DRF63_10415	ENOG4105CFG	Acts as a chaperone (By similarity)
DRF63_10420	ENOG4105CMG	Carbohydrate kinase
DRF63_10425	ENOG4105C93	Xylose Isomerase
DRF63_10430	ENOG4105DFW	ABC transporter
DRF63_10435	ENOG4105C2J	ABC transporter
DRF63_10440	ENOG4108HWW	ABC transporter
DRF63_10445	ENOG4105T16	Transcriptional regulator (AraC family)
DRF63_10450	ENOG4105C9K	Endothelin-converting enzyme 1
DRF63_10460	ENOG4108IA2	Sodium pantothenate symporter
DRF63_10465	ENOG4105RG0	Membrane
DRF63_10470	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
DRF63_10475	ENOG410903C	(LipO)protein
DRF63_10480	ENOG4105DSB	aldose 1-epimerase
DRF63_10495	ENOG4107BJW	polysaccharide deacetylase
DRF63_10500	ENOG4105CND	Glycosyl transferase, family 2
DRF63_10510	ENOG4105CP7	Triose-phosphate isomerase
DRF63_10515	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
DRF63_10520	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
DRF63_10525	ENOG4108UM1	dedA family
DRF63_10540	ENOG4108K5P	(LipO)protein
DRF63_10545	ENOG4108R3E	Dna-3-methyladenine glycosylase i
DRF63_10555	ENOG4108P2H	Inner membrane protein YjiG
DRF63_10560	ENOG41074DU	domain protein
DRF63_10565	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
DRF63_10570	ENOG4105VG0	50S ribosomal protein l34
DRF63_10575	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
DRF63_10580	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
DRF63_10585	ENOG4105C5F	glutamine synthetase
DRF63_10590	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
DRF63_10595	ENOG41087AY	ADP-Ribose pyrophosphatase
DRF63_10600	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
DRF63_10605	ENOG4105W8Z	4'-phosphopantetheinyl transferase
DRF63_10625	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
DRF63_10630	ENOG4107S2Z	UPF0761 membrane protein
DRF63_10635	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
DRF63_10670	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
DRF63_10675	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DRF63_10680	ENOG4108URH	decarboxylase
DRF63_10685	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
DRF63_10690	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
DRF63_10695	ENOG4105YP7	UPF0270 protein
DRF63_10700	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
DRF63_10710	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DRF63_10715	ENOG4105W5Q	DNA repair protein (RadC
DRF63_10720	ENOG4105KDC	50s ribosomal protein l28
DRF63_10725	ENOG4105W0E	50S ribosomal protein L33
DRF63_10735	ENOG4108JPW	Aminotransferase
DRF63_10740	ENOG4105DY8	decarboxylase
DRF63_10745	ENOG4105KSU	Redox protein
DRF63_10750	ENOG41066VF	YeeE YedE family protein
DRF63_10755	ENOG4108WFC	UPF0438 protein yifE
DRF63_10775	ENOG4107QUT	magnesium and cobalt transport protein CorA
DRF63_10780	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DRF63_10790	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
DRF63_10795	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
DRF63_10800	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
DRF63_10805	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
DRF63_10810	ENOG4105D52	delta-aminolevulinic acid dehydratase
DRF63_10825	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
DRF63_10830	ENOG4105CHR	reductase
DRF63_10835	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
DRF63_10840	ENOG4105WPN	DNA integration recombination invertion protein
DRF63_10845	ENOG4105EAH	synthase
DRF63_10855	ENOG4108YYH	Nadph-dependent fmn reductase
DRF63_10860	ENOG4105MGM	doxx family
DRF63_10865	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
DRF63_10870	ENOG4105K46	50S ribosomal protein l27
DRF63_10875	ENOG4105QYV	Membrane
DRF63_10890	ENOG4105MJ2	Competence protein
DRF63_10905	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
DRF63_10910	ENOG4105C1J	atp-dependent rna helicase
DRF63_10920	ENOG4105DEF	Extracellular solute-binding protein, family 5
DRF63_10930	ENOG4106HK8	GPR1 FUN34 yaaH family protein
DRF63_10935	ENOG4105E0A	ABC, transporter
DRF63_10945	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
DRF63_10970	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DRF63_10975	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DRF63_10995	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
DRF63_11010	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
DRF63_11015	ENOG4105EX9	Membrane
DRF63_11020	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
DRF63_11030	ENOG4105WBN	Transcriptional regulator (LacI family
DRF63_11040	ENOG4105D7K	pfkb domain protein
DRF63_11045	ENOG4105CEI	nitrite reductase
DRF63_11050	ENOG4105D60	lipoprotein releasing system transmembrane protein
DRF63_11055	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DRF63_11060	ENOG4105D60	lipoprotein releasing system transmembrane protein
DRF63_11065	ENOG4105C5I	Dehydrogenase
DRF63_11075	ENOG41063JG	Transcriptional regulator
DRF63_11080	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)